Aging genes 1-2

• Genes with 300 and more publications
• Genes with 200-299 publications
• Genes with 100-199 publications
• Genes with 90-99 publications
• Genes with 80-89 publications
• Genes with 70-79 publications
• Genes with 60-69 publications
• Genes with 50-59 publications
• Genes with 40-49 publications
• Genes with 30-39 publications
• Genes with 20-29 publications
• Genes with 10-19 publications
• Genes with 5-9 publications
• Genes with 3-4 publications
• Genes with 1-2 publications
• Aging_genes_A-Z_table

AACS

• Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study. / 07.11.2020 / PubMed / Full text
• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

ABCC2

• Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life. / 07.2016 / PubMed / Full text
• Developmental characteristics of urinary coproporphyrin I/(I III) ratio. / 10.2016 / PubMed / Full text

ABCG1

• Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. / 08.2018 / PubMed / Full text
• Elevated COX2 expression and PGE2 production by downregulation of RXRα in senescent macrophages. / 11.10.2013 / PubMed / Full text

ABCG5

• 2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. / 01.04.2019 / PubMed / Full text
• Genetic determinants of macular pigments in women of the Carotenoids in Age-Related Eye Disease Study. / 28.03.2013 / PubMed / Full text

ABI3

• Arabidopsis seed-specific vacuolar aquaporins are involved in maintaining seed longevity under the control of ABSCISIC ACID INSENSITIVE 3. / 08.2015 / PubMed / Full text
• A forward genetic approach in Arabidopsis thaliana identifies a RING-type ubiquitin ligase as a novel determinant of seed longevity. / 02.2014 / PubMed / Full text

ACACA

• Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
• GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling. / 07.2018 / PubMed / Full text

ACAT2

• Cholesterol Homeostasis: An In Silico Investigation into How Aging Disrupts Its Key Hepatic Regulatory Mechanisms. / 30.09.2020 / PubMed / Full text
• Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. / 15.12.2017 / PubMed / Full text

ACTA1

• Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. / 15.05.2019 / PubMed / Full text
• Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. / 15.12.2017 / PubMed / Full text

ACTB

• Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text
• WNT-activated bone grafts repair osteonecrotic lesions in aged animals. / 27.10.2017 / PubMed / Full text

ACVR1

• Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome. / 2019 / PubMed / Full text
• BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence. / 15.11.2016 / PubMed / Full text

ADAMTS4

• Influences of circulatory factors on intervertebral disc aging phenotype. / 11.06.2020 / PubMed / Full text
• Genotoxic stress accelerates age-associated degenerative changes in intervertebral discs. / 01-02.2013 / PubMed / Full text

ADH5

• Can Serum Nitrosoproteome Predict Longevity of Aged Women? / 27.11.2020 / PubMed / Full text
• Denitrosylate and live longer: how ADH5/GSNOR links mitophagy to aging. / 2018 / PubMed / Full text

ADIPOR1

• A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. / 2018 / PubMed / Full text
• Contribution of adiponectin and its type 1 receptor to age-related hearing impairment. / 06.2015 / PubMed / Full text

ADNP

• ADNP differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. / 06.2019 / PubMed / Full text
• ADNP: A major autism mutated gene is differentially distributed (age and gender) in the songbird brain. / 10.2015 / PubMed / Full text

ADRA2B

• Aging and the Combined effects of ADRA2B and CB1 deletions on Affective Working Memory. / 11.03.2019 / PubMed / Full text
• Aging and the genetic road towards the positivity effect in memory. / 09.2016 / PubMed / Full text

ADRB2

• Interactions between social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China. / 09.09.2013 / PubMed / Full text
• ADRB2, brain white matter integrity and cognitive ageing in the Lothian Birth Cohort 1936. / 01.2013 / PubMed / Full text

AGO2

• Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. / 06.2018 / PubMed / Full text
• miRNA processing gene polymorphisms, blood DNA methylation age and long-term ambient PM exposure in elderly men. / 12.2017 / PubMed / Full text

AHCY

• Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
• Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila. / 15.06.2016 / PubMed / Full text

AIDA

• Identification of Postharvest Senescence Regulators Through Map-Based Cloning Using Detached Arabidopsis Inflorescences as a Model Tissue. / 2018 / PubMed / Full text
• Interaction of DHPG-LTD and synaptic-LTD at senescent CA3-CA1 hippocampal synapses. / 04.2014 / PubMed / Full text

AKT2

• A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster. / 08.2019 / PubMed / Full text
• Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

AKT3

• Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma. / 10.2018 / PubMed / Full text
• MicroRNA-22 induces endothelial progenitor cell senescence by targeting AKT3. / 2014 / PubMed / Full text

AKTIP

• Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits. / 08.2018 / PubMed / Full text
• The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence. / 08.2016 / PubMed / Full text

ALDOA

• Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text
• An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. / 06.2019 / PubMed / Full text

ALKBH8

• Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming . / 01.2020 / PubMed / Full text
• ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed

ALOX5

• Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis. / 19.12.2019 / PubMed / Full text
• Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme. / 01.01.2020 / PubMed / Full text

ANK1

• Alzheimer's Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in [i]Drosophila[/i]. / 2019 / PubMed / Full text
• DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

ANK3

• Age-related atrophy of cortical thickness and genetic effect of ANK3 gene in first episode MDD patients. / 26.08.2020 / PubMed / Full text
• Mood, stress and longevity: convergence on ANK3. / 08.2016 / PubMed / Full text

AP2B1

• Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice. / 20.12.2019 / PubMed / Full text
• Investigating the specific core genetic-and-epigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells. / 23.02.2016 / PubMed / Full text

APOD

• Identification of reference genes for RT-qPCR data normalisation in aging studies. / 27.09.2019 / PubMed / Full text
• Apolipoprotein D takes center stage in the stress response of the aging and degenerative brain. / 07.2014 / PubMed / Full text

APOL1

• APOL1 Risk Alleles Are Associated with Exaggerated Age-Related Changes in Glomerular Number and Volume in African-American Adults: An Autopsy Study. / 12.2015 / PubMed / Full text
• Apolipoprotein L1, income and early kidney damage. / 10.02.2015 / PubMed / Full text

APPL2

• The reversal effect of physical exercise on aging-related increases in APPL2 content in skeletal muscle. / 01.10.2018 / PubMed / Full text
• Adaptor Protein APPL2 Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor. / 07.2018 / PubMed / Full text

AQP2

• A bell-shaped pattern of urinary aquaporin-2-bearing extracellular vesicle release in an experimental model of nephronophthisis. / 05.2019 / PubMed / Full text
• Nitric oxide and AQP2 in hypothyroid rats: a link between aging and water homeostasis. / 09.2013 / PubMed / Full text

AQP3

• Transbuccal platform for delivery of lipogenic actives to facial skin: Because fat matters. / 08.2020 / PubMed / Full text
• [Age-related changes of water transport by corneal endothelial cells in rats.] / 2017 / PubMed

ARID1B

• A 69-year-old woman with Coffin-Siris syndrome. / 08.2018 / PubMed / Full text
• SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer. / 01.10.2016 / PubMed / Full text

ARX

• Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx. / 07.03.2017 / PubMed / Full text
• Acacetin 7-O-α-l-rhamnopyranosyl (1-2) β-D-xylopyranoside Elicits Life-span Extension and Stress Resistance in Caenorhabditis elegans. / 09.2016 / PubMed / Full text

ASXL2

• Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. / 10.2016 / PubMed / Full text
• The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. / 27.11.2015 / PubMed / Full text

ATF2

• Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium. / 01.04.2018 / PubMed / Full text
• Prmt7 Deficiency Causes Reduced Skeletal Muscle Oxidative Metabolism and Age-Related Obesity. / 07.2016 / PubMed / Full text

ATF7

• Stress-induced and ATF7-dependent epigenetic change influences cellular senescence. / 09.2019 / PubMed / Full text
• Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species. / 2017 / PubMed / Full text

ATG9A

• SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy. / 08.2019 / PubMed / Full text
• Activation of miR-34a impairs autophagic flux and promotes cochlear cell death via repressing ATG9A: implications for age-related hearing loss. / 05.10.2017 / PubMed / Full text

ATOH1

• In Vivo Interplay between p27 , GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice. / 11.04.2017 / PubMed / Full text
• A new mutation of the Atoh1 gene in mice with normal life span allows analysis of inner ear and cerebellar phenotype in aging. / 2013 / PubMed / Full text

ATP1A2

• SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
• The Influence of Na( ), K( )-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. / 2016 / PubMed / Full text

ATP6V1E1

• Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text
• Chemical screening identifies ATM as a target for alleviating senescence. / 06.2017 / PubMed / Full text

ATP7A

• Adipocyte-specific disruption of ATPase copper transporting α in mice accelerates lipoatrophy. / 12.2019 / PubMed / Full text
• TAp73 regulates ATP7A: possible implications for ageing-related diseases. / 08.12.2018 / PubMed / Full text

ATXN3

• Rescue of ATXN3 neuronal toxicity in [i]Caenorhabditis[/i][i]elegans[/i] by chemical modification of endoplasmic reticulum stress. / 19.12.2017 / PubMed / Full text
• Sodium valproate alleviates neurodegeneration in SCA3/MJD via suppressing apoptosis and rescuing the hypoacetylation levels of histone H3 and H4. / 2013 / PubMed / Full text

AXL

• Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells. / 01.2020 / PubMed / Full text
• CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN. / 04.2017 / PubMed / Full text

B4GALT1

• Expression of β-1,4-galactosyltransferases during Aging in Caenorhabditis elegans. / 2020 / PubMed / Full text
• Glycobiology of Aging. / 2018 / PubMed / Full text

BACH2

• Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients. / 17.01.2019 / PubMed / Full text
• BACH2: a marker of DNA damage and ageing. / 11.2013 / PubMed / Full text

BAG3

• Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner. / 03.2018 / PubMed / Full text
• Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans. / 06.10.2015 / PubMed / Full text

BANF1

• An additional case of Néstor-Guillermo progeria syndrome diagnosed in early childhood. / 10.2020 / PubMed / Full text
• Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation. / 12.12.2014 / PubMed / Full text

BARD1

• BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in [i]Caenorhabditis elegans[/i]. / 12.2018 / PubMed / Full text
• The Histone Variant MacroH2A1 Is a BRCA1 Ubiquitin Ligase Substrate. / 30.05.2017 / PubMed / Full text

BCL11B

• Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells. / 05.2018 / PubMed / Full text
• Age-related profiling of DNA methylation in CD8 T cells reveals changes in immune response and transcriptional regulator genes. / 19.08.2015 / PubMed / Full text

BCL2L1

• The transcription factor ETS1 promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1. / 06.12.2019 / PubMed / Full text
• SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

BMPR1B

• Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes. / 12.2018 / PubMed / Full text
• Dysregulation of granulosal bone morphogenetic protein receptor 1B density is associated with reduced ovarian reserve and the age-related decline in human fertility. / 15.04.2016 / PubMed / Full text

BMX

• Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation. / 11.2017 / PubMed / Full text
• Enhanced activity of an angiotensin-(1-7) neuropeptidase in glucocorticoid-induced fetal programming. / 02.2014 / PubMed / Full text

BRD2

• Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice. / 2020 / PubMed / Full text
• Genetic architecture differences between pediatric and adult-onset inflammatory bowel diseases in the Polish population. / 23.12.2016 / PubMed / Full text

BTC

• Behavioral tagging and capture: long-term memory decline in middle-aged rats. / 07.2018 / PubMed / Full text
• Estimates of genetic parameters for content of boar taint compounds in adipose tissue of intact males at 160 and 220 days of age. / 09.2015 / PubMed / Full text

BTG1

• Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells. / 09.2020 / PubMed / Full text
• Tumor cell escape from therapy-induced senescence. / 04.2019 / PubMed / Full text

BTK

• Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition. / 01.2020 / PubMed / Full text
• BTK suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling. / 22.08.2017 / PubMed / Full text

BTLA

• Combinatorial approach to cancer immunotherapy: strength in numbers. / 08.2016 / PubMed / Full text
• BTLA expression declines on B cells of the aged and is associated with low responsiveness to the trivalent influenza vaccine. / 14.08.2015 / PubMed / Full text

CA12

• Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text
• Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration. / 04.05.2017 / PubMed / Full text

CACNA1C

• Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk. / 04.2020 / PubMed / Full text
• Epigenetic regulation of L-type voltage-gated Ca channels in mesenteric arteries of aging hypertensive rats. / 05.2017 / PubMed / Full text

CALR

• Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes. / 15.01.2020 / PubMed / Full text
• Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender. / 10.2017 / PubMed / Full text

CASK

• Integrated study on comparative transcriptome and skeletal muscle function in aged rats. / 01.2018 / PubMed / Full text
• Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex. / 01.01.2017 / PubMed / Full text

CASP1

• White Matter Abnormalities Linked to Interferon, Stress Response, and Energy Metabolism Gene Expression Changes in Older HIV-Positive Patients on Antiretroviral Therapy. / 02.2020 / PubMed / Full text
• Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age. / 2015 / PubMed / Full text

CASP7

• Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence. / 2015 / PubMed / Full text
• Dual role of the caspase enzymes in satellite cells from aged and young subjects. / 12.12.2013 / PubMed / Full text

CASP8

• Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. / 05.2020 / PubMed / Full text
• [Association of polymorphic markers of CASP8, BCL2 and BAX genes with aging and longevity]. / 2012 / PubMed

CASQ2

• Single delivery of an adeno-associated viral construct to transfer the CASQ2 gene to knock-in mice affected by catecholaminergic polymorphic ventricular tachycardia is able to cure the disease from birth to advanced age. / 24.06.2014 / PubMed / Full text
• The role of mutant protein level in autosomal recessive catecholamine dependent polymorphic ventricular tachycardia (CPVT2). / 01.12.2013 / PubMed / Full text

CAST

• Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance. / 05.11.2018 / PubMed / Full text
• Short Telomeres Induce p53 and Autophagy and Modulate Age-Associated Changes in Cardiac Progenitor Cell Fate. / 06.2018 / PubMed / Full text

CAV1

• Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. / 03.2020 / PubMed / Full text
• Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine. / 24.04.2019 / PubMed / Full text

CBX4

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text
• Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis. / 26.03.2019 / PubMed / Full text

CBX8

• PIM1-catalyzed CBX8 phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast. / 27.06.2018 / PubMed / Full text
• CBX8 antagonizes the effect of Sirtinol on premature senescence through the AKT-RB-E2F1 pathway in K562 leukemia cells. / 22.01.2016 / PubMed / Full text

CCL13

• Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text
• Differential Gene Expression Profiles Reflecting Macrophage Polarization in Aging and Periodontitis Gingival Tissues. / 2015 / PubMed / Full text

CCL17

• Aging and chronic high-fat feeding negatively affects kidney size, function, and gene expression in CTRP1-deficient mice. / 21.10.2020 / PubMed / Full text
• Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. / 21.05.2019 / PubMed / Full text

CCL24

• Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text
• Anserine/Carnosine Supplementation Suppresses the Expression of the Inflammatory Chemokine CCL24 in Peripheral Blood Mononuclear Cells from Elderly People. / 31.10.2017 / PubMed / Full text

CCL7

• Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis. / 01.2020 / PubMed / Full text
• Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension. / 02.2017 / PubMed / Full text

CCNG2

• A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. / 2018 / PubMed / Full text
• Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text

CCR4

• mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and PAPPA-KO mice. / 02.2017 / PubMed / Full text
• Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects. / 10.2016 / PubMed / Full text

CD209

• Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity. / 2020 / PubMed / Full text
• Comparative analysis of microbial sensing molecules in mucosal tissues with aging. / 03.2018 / PubMed / Full text

CD46

• Soluble forms of CD46 are detected in Bos taurus plasma and neutralize BVDV, the bovine pestivirus. / 12.2016 / PubMed / Full text
• Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating CD200-CD200R interaction involve the cannabinoid system. / 2014 / PubMed / Full text

CD70

• CD70 contributes to age-associated T cell defects and overwhelming inflammatory responses. / 19.06.2020 / PubMed / Full text
• Molecular mechanisms involved in the aging of the T-cell immune response. / 12.2012 / PubMed / Full text

CDH1

• Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation. / 15.09.2020 / PubMed / Full text
• A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer. / 04.2017 / PubMed / Full text

CDKN1B

• A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. / 2018 / PubMed / Full text
• RNA methyltransferase NSUN2 promotes stress-induced HUVEC senescence. / 12.04.2016 / PubMed / Full text

CDKN1C

• Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text
• Expansion of adipose tissue-derived stromal cells at "physiologic" hypoxia attenuates replicative senescence. / 06.2017 / PubMed / Full text

CDR1

• Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires. / 2018 / PubMed / Full text
• Neuro-degeneration profile of Alzheimer's patients: A brain morphometry study. / 2017 / PubMed / Full text

CDX2

• Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. / 08.07.2019 / PubMed / Full text
• Autophagic homeostasis is required for the pluripotency of cancer stem cells. / 02.2017 / PubMed / Full text

CEBPB

• Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text
• The microRNA miR-17-3p inhibits mouse cardiac fibroblast senescence by targeting Par4. / 15.01.2015 / PubMed / Full text

CELF1

• Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
• Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. / 04.2016 / PubMed / Full text

CHEK1

• Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. / 03.2020 / PubMed / Full text
• The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence. / 03.03.2017 / PubMed / Full text

CHEK2

• Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes. / 15.01.2020 / PubMed / Full text
• A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text

CHI3L1

• Postsynaptic damage and microglial activation in AD patients could be linked CXCR4/CXCL12 expression levels. / 15.12.2020 / PubMed / Full text
• Sex difference in CHI3L1 expression levels in human brain aging and in Alzheimer's disease. / 01.10.2019 / PubMed / Full text

CHIA

• Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets. / 26.11.2018 / PubMed / Full text
• Chia Oil-Enriched Restructured Pork Effects on Oxidative and Inflammatory Status of Aged Rats Fed High Cholesterol/High Fat Diets. / 05.2017 / PubMed / Full text

CHL1

• Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B. / 07.08.2019 / PubMed / Full text
• Age-dependent loss of parvalbumin-expressing hippocampal interneurons in mice deficient in CHL1, a mental retardation and schizophrenia susceptibility gene. / 11.2015 / PubMed / Full text

CHM

• [Molecular regulative mechanisms of aging and interventional effects of Chinese herbal medicine]. / 08.2017 / PubMed / Full text
• [Molecular mechanisms of autophagy in regulating renal aging and interventional effects of Chinese herbal medicine]. / 11.2016 / PubMed / Full text

CIDEA

• Growth hormone receptor expression in human gluteal versus abdominal subcutaneous adipose tissue: Association with body shape. / 05.2016 / PubMed / Full text
• The developmental transition of ovine adipose tissue through early life. / 01.2014 / PubMed / Full text

CIP2A

• Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy. / 12.02.2020 / PubMed / Full text
• Inhibition of CIP2A attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma. / 08.01.2018 / PubMed / Full text

CLC

• Impact of Intervention to Improve Nursing Home Resident-Staff Interactions and Engagement. / 13.07.2018 / PubMed / Full text
• Effect of cholesterol loaded cyclodextrin on semen cryopreservation of Aksaray Malakli shepherd dogs of different ages. / 06.2018 / PubMed / Full text

CLEC3B

• CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging. / 16.09.2020 / PubMed / Full text
• Exome-wide Association Study Identifies CLEC3B Missense Variant p.S106G as Being Associated With Extreme Longevity in East Asian Populations. / 01.03.2017 / PubMed / Full text

CLPP

• Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging. / 02.2019 / PubMed / Full text
• Mitochondrial unfolded protein response gene Clpp is required to maintain ovarian follicular reserve during aging, for oocyte competence, and development of pre-implantation embryos. / 08.2018 / PubMed / Full text

CLSTN2

• Investigating the influence of KIBRA and CLSTN2 genetic polymorphisms on cross-sectional and longitudinal measures of memory performance and hippocampal volume in older individuals. / 11.2015 / PubMed / Full text
• Genetic effects on old-age cognitive functioning: a population-based study. / 03.2013 / PubMed / Full text

CNP

• Environmental Enrichment Elicits a Transient Rise of Bioactive C-Type Natriuretic Peptide in Young but Not Aged Rats. / 2018 / PubMed / Full text
• In aging, the vulnerability of rat brain mitochondria is enhanced due to reduced level of 2',3'-cyclic nucleotide-3'-phosphodiesterase (CNP) and subsequently increased permeability transition in brain mitochondria in old animals. / 01.2015 / PubMed / Full text

CNTF

• Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha. / 01.10.2019 / PubMed / Full text
• Maintenance of membrane organization in the aging mouse brain as the determining factor for preventing receptor dysfunction and for improving response to anti-Alzheimer treatments. / 06.2017 / PubMed / Full text

CNTNAP2

• Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text
• A common copy number variation polymorphism in the CNTNAP2 gene: sexual dimorphism in association with healthy aging and disease. / 2015 / PubMed / Full text

COPE

• Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the COPE-study. / 09.04.2020 / PubMed / Full text
• Falls self-efficacy and falls incidence in community-dwelling older people: the mediating role of coping. / 05.2018 / PubMed / Full text

COQ7

• Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text
• Gene expression differences in relation to age and social environment in queen and worker bumble bees. / 05.2016 / PubMed / Full text

COX5B

• Role of Mitochondrial Complex IV in Age-Dependent Obesity. / 13.09.2016 / PubMed / Full text
• Loss of COX5B inhibits proliferation and promotes senescence via mitochondrial dysfunction in breast cancer. / 22.12.2015 / PubMed / Full text

CPNE1

• Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence. / 04.12.2020 / PubMed / Full text
• Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2. / 05.12.2019 / PubMed / Full text

CPQ

• A Spanish Adaptation of the Computer and Mobile Device Proficiency Questionnaires (CPQ and MDPQ) for Older Adults. / 2019 / PubMed / Full text
• Protective Effect of Semisynthetic and Natural Flavonoid on Aged Rat Microglia-enriched Cultures. / 11.2019 / PubMed / Full text

CPT1B

• Effects of carnitine palmitoyltransferases on cancer cellular senescence. / 02.2019 / PubMed / Full text
• Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone. / 07.2014 / PubMed / Full text

CPT2

• The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats. / 09.2020 / PubMed / Full text
• Glial β-oxidation regulates Drosophila energy metabolism. / 15.01.2015 / PubMed / Full text

CRABP2

• Preconception resveratrol intake against infertility: Friend or foe? / 04.2020 / PubMed / Full text
• Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females. / 31.10.2017 / PubMed / Full text

CREB5

• Cellular senescence induces replication stress with almost no affect on DNA replication timing. / 2018 / PubMed / Full text
• Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90 study. / 08.2015 / PubMed / Full text

CREBBP

• Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. / 22.07.2019 / PubMed / Full text
• Genetic variants in a 'cAMP element binding protein' (CREB)-dependent histone acetylation pathway influence memory performance in cognitively healthy elderly individuals. / 12.2014 / PubMed / Full text

CRYAB

• Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells. / 28.12.2018 / PubMed / Full text
• Quantitative proteomics analysis by iTRAQ in human nuclear cataracts of different ages and normal lens nuclei. / 08.2015 / PubMed / Full text

CSRP1

• FOXO3, a Molecular Search for the Fountain of Youth. / 07.03.2019 / PubMed / Full text
• FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. / 07.03.2019 / PubMed / Full text

CYB5A

• 11-Oxygenated C19 Steroids Do Not Decline With Age in Women. / 01.07.2019 / PubMed / Full text
• 3βHSD and CYB5A double positive adrenocortical cells during adrenal development/aging. / 2015 / PubMed / Full text

CYP11B2

• Expression of aldosterone synthase CYP11B2 was inversely correlated with longevity. / 07.2019 / PubMed / Full text
• Age-Related Autonomous Aldosteronism. / 25.07.2017 / PubMed / Full text

CYP27A1

• Prenatal betaine exposure alleviates corticosterone-induced inhibition of CYP27A1 expression in the liver of juvenile chickens associated with its promoter DNA methylation. / 15.05.2017 / PubMed / Full text
• Synergic hypocholesterolaemic effect of n-3 PUFA and oestrogen by modulation of hepatic cholesterol metabolism in female rats. / 14.12.2015 / PubMed / Full text

CYP2A6

• Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits. / 06.2017 / PubMed / Full text
• Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes. / 02.2017 / PubMed / Full text

CYP2C8

• Paclitaxel-induced sensory peripheral neuropathy is associated with an ABCB1 single nucleotide polymorphism and older age in Japanese. / 06.2017 / PubMed / Full text
• Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages. / 05.2017 / PubMed / Full text

CYP3A7

• Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers. / 07.2016 / PubMed / Full text
• Predicting the "First dose in children" of CYP3A-metabolized drugs: Evaluation of scaling approaches and insights into the CYP3A7-CYP3A4 switch at young ages. / 09.2014 / PubMed / Full text

DAO

• Age- and gender-dependent D-amino acid oxidase activity in mouse brain and peripheral tissues: implication for aging and neurodegeneration. / 01.08.2019 / PubMed / Full text
• Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging. / 01.11.2017 / PubMed / Full text

DAPK1

• SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
• Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging. / 05.2019 / PubMed / Full text

DAZL

• DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions. / 30.10.2018 / PubMed / Full text
• No evidence for neo-oogenesis may link to ovarian senescence in adult monkey. / 11.2013 / PubMed / Full text

DBT

• Diurnal rhythms of heart and respiratory rates in donkeys of different age groups during the cold-dry and hot-dry seasons in a tropical savannah. / 09.2018 / PubMed / Full text
• Anodal Transcranial Direct Current Stimulation Does Not Facilitate Dynamic Balance Task Learning in Healthy Old Adults. / 2017 / PubMed / Full text

DCTN3

• Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text
• Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis. / 2016 / PubMed / Full text

DDAH1

• Dimethylarginine Dimethylaminohydrolase 1 Deficiency Induces the Epithelial to Mesenchymal Transition in Renal Proximal Tubular Epithelial Cells and Exacerbates Kidney Damage in Aged and Diabetic Mice. / 01.12.2017 / PubMed / Full text
• Epigallocatechin-3-gallate ameliorates erectile function in aged rats via regulation of PRMT1/DDAH/ADMA/NOS metabolism pathway. / 05-06.2017 / PubMed / Full text

DDAH2

• Epigallocatechin-3-gallate ameliorates erectile function in aged rats via regulation of PRMT1/DDAH/ADMA/NOS metabolism pathway. / 05-06.2017 / PubMed / Full text
• Regulation of endothelial progenitor cell differentiation and function by dimethylarginine dimethylaminohydrolase 2 in an asymmetric dimethylarginine-independent manner. / 09.2014 / PubMed / Full text

DDB1

• DCAF1 regulates Treg senescence via the ROS axis during immunological aging. / 02.11.2020 / PubMed / Full text
• Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. / 15.06.2018 / PubMed / Full text

DDR2

• Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging. / 03.2018 / PubMed / Full text
• Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression. / 03.05.2016 / PubMed / Full text

DDX41

• Salidroside influences the cellular cross-talk of human fetal lung diploid fibroblasts: A proteomic approach. / 03.2018 / PubMed / Full text
• Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text

DEGS1

• [Frailty: Prevalence in the Resident Population of Germany 70 - 79 Years of Age - a Population-Based Approach]. / 11.2017 / PubMed / Full text
• Physical exercise and cognitive function across the life span: Results of a nationwide population-based study. / 05.2018 / PubMed / Full text

DHFR

• Excessive folic acid intake and relation to adverse health outcome. / 07.2016 / PubMed / Full text
• Increase in tetrahydrobiopterin concentration with aging in the cerebral cortex of the senescence-accelerated mouse prone 10 strain caused by abnormal regulation of tetrahydrobiopterin biosynthesis. / 10.2013 / PubMed / Full text

DHX9

• The biology of DHX9 and its potential as a therapeutic target. / 05.07.2016 / PubMed / Full text
• Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner. / 15.08.2014 / PubMed / Full text

DIAPH1

• Diaphanous 1 (DIAPH1) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease. / 2018 / PubMed / Full text
• The multiple faces of RAGE--opportunities for therapeutic intervention in aging and chronic disease. / 2016 / PubMed / Full text

DIRAS3

• Silencing of the small GTPase DIRAS3 induces cellular senescence in human white adipose stromal/progenitor cells. / 17.03.2017 / PubMed / Full text
• Weight Loss Upregulates the Small GTPase DIRAS3 in Human White Adipose Progenitor Cells, Which Negatively Regulates Adipogenesis and Activates Autophagy via Akt-mTOR Inhibition. / 04.2016 / PubMed / Full text

DKK2

• Low Serum Levels of DKK2 Predict Incident Low-Impact Fracture in Older Women. / 07.2019 / PubMed / Full text
• Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text

DLC1

• Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells. / 15.09.2018 / PubMed / Full text
• Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence. / 09.2013 / PubMed / Full text

DLX5

• Inhibition of microRNA-27b-3p relieves osteoarthritis pain via regulation of KDM4B-dependent DLX5. / 09.2020 / PubMed / Full text
• Detection and evaluation of DNA methylation markers found at SCGN and KLF14 loci to estimate human age. / 11.2017 / PubMed / Full text

DNA2

• 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. / 02.01.2020 / PubMed / Full text
• Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing. / 08.10.2019 / PubMed / Full text

DNAJC5

• Gene Therapy of Adult Neuronal Ceroid Lipofuscinoses with CRISPR/Cas9 in Zebrafish. / 07.2017 / PubMed / Full text
• Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol. / 15.11.2014 / PubMed / Full text

DOCK11

• [Immunosenescence: The Forefront of Infection and Trophic Control]. / 2020 / PubMed / Full text
• Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle. / 29.06.2017 / PubMed / Full text

DOT1L

• Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. / 04.2018 / PubMed / Full text
• NF-κB activation impairs somatic cell reprogramming in ageing. / 08.2015 / PubMed / Full text

DRAM1

• Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. / 12.2019 / PubMed / Full text
• Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium. / 27.11.2015 / PubMed / Full text

DRD1

• Impact of dopamine-related genetic variants on physical activity in old age - a cohort study. / 24.05.2020 / PubMed / Full text
• Maternal deprivation enhances behavioral vulnerability to stress associated with miR-504 expression in nucleus accumbens of rats. / 2013 / PubMed / Full text

DROSHA

• Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. / 06.2018 / PubMed / Full text
• Centenarians maintain miRNA biogenesis pathway while it is impaired in octogenarians. / 12.2017 / PubMed / Full text

DSCAM

• Age- and speed-dependent modulation of gaits in DSCAM mutant mice. / 01.02.2018 / PubMed / Full text
• Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. / 2014 / PubMed / Full text

DSG2

• Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
• Age-dependent clinical and genetic characteristics in Japanese patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia. / 2013 / PubMed / Full text

DSPP

• Effects of [i]p[/i]-Cresol on Senescence, Survival, Inflammation, and Odontoblast Differentiation in Canine Dental Pulp Stem Cells. / 21.09.2020 / PubMed / Full text
• GREM1 inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. / 09.03.2020 / PubMed / Full text

DUSP2

• The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort. / 2020 / PubMed / Full text
• Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism. / 2019 / PubMed / Full text

E2F2

• MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment. / 08.2018 / PubMed / Full text
• In situ regeneration of retinal pigment epithelium by gene transfer of E2F2: a potential strategy for treatment of macular degenerations. / 12.2017 / PubMed / Full text

EBF1

• Genome-wide Association Study of Parental Life Span. / 01.10.2017 / PubMed / Full text
• Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice. / 2015 / PubMed / Full text

ECM1

• Novel role of extracellular matrix protein 1 (ECM1) in cardiac aging and myocardial infarction. / 2019 / PubMed / Full text
• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

EDNRB

• Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. / 03.03.2016 / PubMed / Full text
• Variation in genes in the endothelin pathway and endothelium-dependent and endothelium-independent vasodilation in an elderly population. / 05.2013 / PubMed / Full text

EED

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text
• Economic evaluations of eHealth technologies: A systematic review. / 2018 / PubMed / Full text

EIF2B1

• Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
• Infantile onset Vanishing White Matter disease associated with a novel EIF2B5 variant, remarkably long life span, severe epilepsy, and hypopituitarism. / 04.2015 / PubMed / Full text

EIF2B5

• Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
• Infantile onset Vanishing White Matter disease associated with a novel EIF2B5 variant, remarkably long life span, severe epilepsy, and hypopituitarism. / 04.2015 / PubMed / Full text

EIF5A

• The curious case of polyamines: spermidine drives reversal of B cell senescence. / 03.2020 / PubMed / Full text
• Polyamines reverse immune senescence via the translational control of autophagy. / 01.2020 / PubMed / Full text

EN1

• Electrochemically detecting DNA methylation in the EN1 gene promoter: implications for understanding ageing and disease. / 27.11.2020 / PubMed / Full text
• The role of DNA methylation in ageing and cancer. / 11.2018 / PubMed / Full text

ENC1

• Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text
• Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data. / 04.2017 / PubMed / Full text

ENTPD7

• Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 (ENTPD7). / 23.08.2019 / PubMed / Full text
• SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer. / 01.10.2016 / PubMed / Full text

EOMES

• Association of Epigenetic Age and p16INK4a With Markers of T-Cell Composition in a Healthy Cohort. / 13.11.2020 / PubMed / Full text
• Eomesodermin Expression in CD4 T Cells Restricts Peripheral Foxp3 Induction. / 15.11.2015 / PubMed / Full text

EPHA2

• Germ-line and somatic EPHA2 coding variants in lens aging and cataract. / 2017 / PubMed / Full text
• EPHA2 Polymorphisms in Estonian Patients with Age-Related Cataract. / 2016 / PubMed / Full text

EPM2A

• Inflammation in Lafora Disease: Evolution with Disease Progression in Laforin and Malin Knock-out Mouse Models. / 07.2017 / PubMed / Full text
• Loss of GABAergic cortical neurons underlies the neuropathology of Lafora disease. / 28.01.2014 / PubMed / Full text

ERBB2

• The biological age linked to oxidative stress modifies breast cancer aggressiveness. / 20.05.2018 / PubMed / Full text
• Identification of human age-associated gene co-expressions in functional modules using liquid association. / 02.01.2018 / PubMed / Full text

ERCC6

• Two Cockayne Syndrome patients with a novel splice site mutation - clinical and metabolic analyses. / 10.2018 / PubMed / Full text
• The associations between single nucleotide polymorphisms of DNA repair genes, DNA damage, and age-related cataract: Jiangsu Eye Study. / 01.02.2013 / PubMed / Full text

ETS2

• FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16 increase. / 11.2020 / PubMed / Full text
• The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators. / 29.09.2020 / PubMed / Full text

EWSR1

• EWSR1, a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways. / 01.07.2019 / PubMed / Full text
• EWSR1/ELF5 induces acute myeloid leukemia by inhibiting p53/p21 pathway. / 12.2016 / PubMed / Full text

EZR

• Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model. / 03.2018 / PubMed / Full text
• Genetic variations and polymorphisms in the ezrin gene are associated with age-related cataract. / 2013 / PubMed / Full text

F8

• The Pattern of Mu Rhythm Modulation During Emotional Destination Memory: Comparison Between Mild Cognitive Impairment Patients and Healthy Controls. / 2019 / PubMed / Full text
• Correlations between the signal complexity of cerebral and cardiac electrical activity: a multiscale entropy analysis. / 2014 / PubMed / Full text

F9

• Hypermaintenance and hypofunction of aged spermatogonia: insight from age-related increase of Plzf expression. / 30.06.2015 / PubMed / Full text
• eHealth literacy and Web 2.0 health information seeking behaviors among baby boomers and older adults. / 17.03.2015 / PubMed / Full text

FABP1

• The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats. / 09.2020 / PubMed / Full text
• Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken. / 01.09.2019 / PubMed / Full text

FADS1

• Aging and FADS1 polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U- C]linoleic acid. / 09.2019 / PubMed / Full text
• Genetic determinants of macular pigments in women of the Carotenoids in Age-Related Eye Disease Study. / 28.03.2013 / PubMed / Full text

FAHD1

• Oxaloacetate decarboxylase FAHD1 - a new regulator of mitochondrial function and senescence. / 01.2019 / PubMed / Full text
• Depletion of oxaloacetate decarboxylase FAHD1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells. / 06.2017 / PubMed / Full text

FANCD2

• TFG-maintaining stability of overlooked FANCD2 confers early DNA-damage response. / 24.10.2020 / PubMed / Full text
• FANCD2 and DNA Damage. / 19.08.2017 / PubMed / Full text

FAR2

• FAR2 is associated with kidney disease in mice and humans. / 01.08.2018 / PubMed / Full text
• Genetic analysis of mesangial matrix expansion in aging mice and identification of Far2 as a candidate gene. / 12.2013 / PubMed / Full text

FBN1

• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text
• Muscle and Bone Impairment in Children With Marfan Syndrome: Correlation With Age and FBN1 Genotype. / 08.2015 / PubMed / Full text

FBN2

• Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging. / 26.10.2018 / PubMed / Full text
• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

FBXO31

• The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence. / 19.10.2018 / PubMed / Full text
• Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis. / 19.07.2015 / PubMed / Full text

FGF6

• Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. / 06.02.2019 / PubMed / Full text
• Regulation of skeletal muscle stem cells by fibroblast growth factors. / 05.2017 / PubMed / Full text

FGG

• Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults. / 10.2014 / PubMed / Full text
• A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. / 07.2013 / PubMed / Full text

FHL1

• The forkhead-like transcription factor (Fhl1p) maintains yeast replicative lifespan by regulating ribonucleotide reductase 1 (RNR1) gene transcription. / 17.06.2017 / PubMed / Full text
• Transcription factor genes essential for cell proliferation and replicative lifespan in budding yeast. / 31.07.2015 / PubMed / Full text

FLT1

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
• Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. / 08.10.2018 / PubMed / Full text

FOXA2

• Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. / 01.09.2017 / PubMed / Full text
• Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. / 03.2015 / PubMed / Full text

FOXC1

• Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
• FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential. / 15.03.2016 / PubMed / Full text

FOXF1

• Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence. / 17.08.2018 / PubMed / Full text
• Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text

FOXP2

• Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization. / 06.11.2018 / PubMed / Full text
• Human skin keratinocytes can be reprogrammed to express neuronal genes and proteins after a single treatment with decitabine. / 06.2013 / PubMed / Full text

FSTL1

• Blocking the FSTL1-DIP2A Axis Improves Anti-tumor Immunity. / 14.08.2018 / PubMed / Full text
• Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. / 25.11.2013 / PubMed / Full text

FXN

• Two different pathogenic mechanisms, dying-back axonal neuropathy and pancreatic senescence, are present in the YG8R mouse model of Friedreich's ataxia. / 01.06.2016 / PubMed / Full text
• Mitochondrial dysfunction induced by frataxin deficiency is associated with cellular senescence and abnormal calcium metabolism. / 2014 / PubMed / Full text

GABARAP

• Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. / 18.08.2020 / PubMed / Full text
• Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH. / 11.2020 / PubMed / Full text

GAK

• Auxilin Underlies Progressive Locomotor Deficits and Dopaminergic Neuron Loss in a Drosophila Model of Parkinson's Disease. / 31.01.2017 / PubMed / Full text
• Disruption of clathrin-mediated trafficking causes centrosome overduplication and senescence. / 01.2014 / PubMed / Full text

GAS6

• Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text
• Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. / 2017 / PubMed / Full text

GATA2

• GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice. / 04.2019 / PubMed / Full text
• Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text

GCAT

• Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis. / 03.04.2018 / PubMed / Full text
• Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects. / 22.05.2015 / PubMed / Full text

GDF3

• In vivo GDF3 administration abrogates aging related muscle regeneration delay following acute sterile injury. / 10.2018 / PubMed / Full text
• Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. / 05.10.2017 / PubMed / Full text

GIT1

• GIT2-A keystone in ageing and age-related disease. / 05.2018 / PubMed / Full text
• GluN3A promotes dendritic spine pruning and destabilization during postnatal development. / 09.07.2014 / PubMed / Full text

GLI1

• Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text
• GLI1 progenitor cells in the adrenal capsule of the adult mouse give rise to heterotopic gonadal-like tissue. / 05.02.2017 / PubMed / Full text

GLRX

• Gender- and region-dependent changes of redox biomarkers in the brain of successfully aging LOU/C rats. / 07.2015 / PubMed / Full text
• Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. / 04.2014 / PubMed / Full text

GNAQ

• Active notch protects MAPK activated melanoma cell lines from MEK inhibitor cobimetinib. / 14.11.2020 / PubMed / Full text
• GNAQ expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system. / 01.2020 / PubMed / Full text

GNAS

• Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼. / 11.2020 / PubMed / Full text
• Clinical characterization and molecular classification of 12 Korean patients with pseudohypoparathyroidism and pseudopseudohypoparathyroidism. / 10.2013 / PubMed / Full text

GNG3

• Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text
• Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text

GNRH1

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
• Elucidating the genetic architecture of reproductive ageing in the Japanese population. / 17.05.2018 / PubMed / Full text

GP6

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
• Estimation of human age using N-glycan profiles from bloodstains. / 09.2015 / PubMed / Full text

GPER1

• 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Nongenomic effects via the mineralocorticoid receptor. / 07.2017 / PubMed / Full text
• Diverse Synaptic Distributions of G Protein-coupled Estrogen Receptor 1 in Monkey Prefrontal Cortex with Aging and Menopause. / 01.03.2017 / PubMed / Full text

GPR158

• Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip. / 10.2019 / PubMed / Full text
• RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss. / 23.10.2018 / PubMed / Full text

GPR17

• Pharmaceutical Rejuvenation of Age-Associated Decline in Spatial Memory. / 12.2016 / PubMed / Full text
• Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug. / 27.10.2015 / PubMed / Full text

GPR3

• Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue. / 12.10.2015 / PubMed / Full text
• Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. / 07.2015 / PubMed / Full text

GPR39

• Zinc-mediated Neurotransmission in Alzheimer's Disease: A Potential Role of the GPR39 in Dementia. / 2020 / PubMed / Full text
• GPR39 agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence. / 12.2019 / PubMed / Full text

GRB10

• De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver. / 05.2018 / PubMed / Full text
• Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis. / 12.2015 / PubMed / Full text

GRB2

• Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via IRS1/GRB2/ SOS1, GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice. / 21.01.2019 / PubMed / Full text
• The different expression profiles of microRNAs in elderly and young human dental pulp and the role of miR-433 in human dental pulp cells. / 03.2015 / PubMed / Full text

GRIA2

• The EpiTect Methyl qPCR Assay as novel age estimation method in forensic biology. / 07.2016 / PubMed / Full text
• Evaluation of DNA methylation markers and their potential to predict human aging. / 08.2015 / PubMed / Full text

GRIK2

• Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2. / 11-12.2020 / PubMed / Full text
• Isoforms of Ionotropic Glutamate Receptor GRIK2 Induce Senescence of Carcinoma Cells. / 01-02.2019 / PubMed / Full text

GRIN2B

• Medial temporal lobe atrophy relates more strongly to sleep-wake rhythm fragmentation than to age or any other known risk. / 04.2019 / PubMed / Full text
• Gene Expression Switching of Receptor Subunits in Human Brain Development. / 12.2015 / PubMed / Full text

GRM3

• Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk. / 04.2020 / PubMed / Full text
• Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models. / 30.03.2017 / PubMed / Full text

GRSF1

• GRSF1 is an age-related regulator of senescence. / 03.04.2019 / PubMed / Full text
• GRSF1 suppresses cell senescence. / 07.08.2018 / PubMed / Full text

GSTA2

• The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats. / 09.2020 / PubMed / Full text
• The age-related change of glutathione antioxidant system in mice liver. / 07.2013 / PubMed / Full text

GSTA4

• Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue. / 02.2019 / PubMed / Full text
• Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GSTK1

• Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
• Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice. / 10.2014 / PubMed / Full text

GSTM3

• Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
• Relationship Between the Altered Expression and Epigenetics of GSTM3 and Age-Related Cataract. / 01.09.2016 / PubMed / Full text

GSTZ1

• Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
• Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice. / 2014 / PubMed / Full text

HAPLN1

• Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility. / 01.2019 / PubMed / Full text
• Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis. / 01.2019 / PubMed / Full text

HAS1

• A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text
• Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. / 01.2018 / PubMed / Full text

HAS3

• Microneedle fractional radiofrequency increases epidermal hyaluronan and reverses age-related epidermal dysfunction. / 02.2016 / PubMed / Full text
• Age-associated changes in gene expression of goat oocytes. / 01.09.2013 / PubMed / Full text

HAT1

• Activation of p53 by spermine mediates induction of autophagy in HT1080 cells. / 02.2014 / PubMed / Full text
• Age-associated changes in gene expression of goat oocytes. / 01.09.2013 / PubMed / Full text

HBD

• Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection. / 2019 / PubMed / Full text
• Differences in Cytokine Production during Aging and Its Relationship with Antimicrobial Peptides Production. / 01.2017 / PubMed / Full text

HCN3

• Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes. / 11.11.2015 / PubMed / Full text
• Integromics network meta-analysis on cardiac aging offers robust multi-layer modular signatures and reveals micronome synergism. / 04.03.2015 / PubMed / Full text

HCRT

• Age-related central regulation of orexin and NPY in the short-lived African killifish Nothobranchius furzeri. / 15.05.2019 / PubMed / Full text
• Sleep and cardiovascular phenotype in middle-aged hypocretin-deficient narcoleptic mice. / 02.2014 / PubMed / Full text

HELLS

• The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence. / 03.03.2017 / PubMed / Full text
• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

HGD

• High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans. / 2019 / PubMed / Full text
• A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of [i]C. elegans[/i]. / 05.10.2018 / PubMed / Full text

HIF1A

• Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text
• Role of Mitochondrial Complex IV in Age-Dependent Obesity. / 13.09.2016 / PubMed / Full text

HK2

• Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury. / 11.01.2018 / PubMed / Full text
• Differentially expressed microRNAs in bone marrow mesenchymal stem cell-derived microvesicles in young and older rats and their effect on tumor growth factor-β1-mediated epithelial-mesenchymal transition in HK2 cells. / 28.09.2015 / PubMed / Full text

HLA-A

• Reduced expression of the lncRNA NRON is a potential hallmark of the CMV-amplified CD8 T cell accumulations commonly seen in older humans. / 01.2019 / PubMed / Full text
• Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. / 2017 / PubMed / Full text

HLA-B

• Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
• Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. / 2017 / PubMed / Full text

HLA-C

• Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
• Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. / 2017 / PubMed / Full text

HLA-DPB1

• 17th IHIW component "Immunogenetics of Ageing" - New NGS data. / 09.2019 / PubMed / Full text
• Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

HLA-DQA1

• 17th IHIW component "Immunogenetics of Ageing" - New NGS data. / 09.2019 / PubMed / Full text
• [Clinical and genetic characteristics of long-livers in Moscow region]. / 2013 / PubMed

HLA-DQB1

• Identification of new genetic variants of HLA-DQB1 associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population. / 10.11.2017 / PubMed / Full text
• [Clinical and genetic characteristics of long-livers in Moscow region]. / 2013 / PubMed

HMGCS1

• The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain. / 15.10.2018 / PubMed / Full text
• Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging. / 16.09.2014 / PubMed / Full text

HNF4A

• The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing. / 12.2019 / PubMed / Full text
• Hepatocyte Nuclear Factor-4α P2 Promoter Variants Are Associated With the Risk of Metabolic Syndrome and Testosterone Deficiency in Aging Taiwanese Men. / 11.2018 / PubMed / Full text

HNRNPA1

• HNRNPA1-mediated 3' UTR length changes of [i]HN1[/i] contributes to cancer- and senescence-associated phenotypes. / 30.06.2019 / PubMed / Full text
• Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans. / 10.2016 / PubMed / Full text

HOPX

• Combinations of differentiation markers distinguish subpopulations of alveolar epithelial cells in adult lung. / 15.01.2016 / PubMed / Full text
• HOPX is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer. / 02.2015 / PubMed / Full text

HOXC4

• Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text
• Differential DNA Methylation in Relation to Age and Health Risks of Obesity. / 24.07.2015 / PubMed / Full text

HPD

• Protein-Amino Acid Metabolism Disarrangements: The Hidden Enemy of Chronic Age-Related Conditions. / 22.03.2018 / PubMed / Full text
• Post-weaning parental care increases fitness but is not heritable in North American red squirrels. / 06.2015 / PubMed / Full text

HRG

• Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice. / 10.2017 / PubMed / Full text
• Heregulin, a new regulator of telomere length in human cells. / 24.11.2015 / PubMed / Full text

HSD3B2

• 11-Oxygenated C19 Steroids Do Not Decline With Age in Women. / 01.07.2019 / PubMed / Full text
• Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs. / 01.03.2017 / PubMed / Full text

HSF4

• Effect of HSF4b on age related cataract may through its novel downstream target Hif1α. / 24.10.2014 / PubMed / Full text
• Copy number variations of DNA repair genes and the age-related cataract: Jiangsu Eye Study. / 01.02.2013 / PubMed / Full text

HSP90AA1

• SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
• Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo. / 31.07.2015 / PubMed / Full text

HSPB1

• The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity. / 06.2019 / PubMed / Full text
• Chicken heat shock protein HSPB1 increases and interacts with αB-crystallin in aged skeletal muscle. / 2015 / PubMed / Full text

HSPB6

• Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
• Apoptosis in muscle-to-meat aging process: The omic witness. / 01.07.2015 / PubMed / Full text

HUS1

• Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes. / 19.10.2015 / PubMed / Full text
• [Role of DNA repair genes in radiation-induced changes of lifespan of Drosophila melanogaster]. / 09-10.2014 / PubMed

IAPP

• Protein aggregates and proteostasis in aging: Amylin and β-cell function. / 01.2019 / PubMed / Full text
• Causative factors for formation of toxic islet amyloid polypeptide oligomer in type 2 diabetes mellitus. / 2015 / PubMed / Full text

ID2

• Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
• Ablation of the ID2 gene results in altered circadian feeding behavior, and sex-specific enhancement of insulin sensitivity and elevated glucose uptake in skeletal muscle and brown adipose tissue. / 2013 / PubMed / Full text

ID3

• Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text
• Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

IDO1

• Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. / 21.12.2019 / PubMed / Full text
• Advanced age negatively impacts survival in an experimental brain tumor model. / 06.09.2016 / PubMed / Full text

IFIT1

• Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text
• Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. / 02.08.2017 / PubMed / Full text

IFIT3

• Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. / 02.08.2017 / PubMed / Full text
• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

IFITM1

• White Matter Abnormalities Linked to Interferon, Stress Response, and Energy Metabolism Gene Expression Changes in Older HIV-Positive Patients on Antiretroviral Therapy. / 02.2020 / PubMed / Full text
• Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection. / 10.11.2018 / PubMed / Full text

IFITM3

• Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals. / 22.07.2020 / PubMed / Full text
• Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3. / 25.06.2019 / PubMed / Full text

IFNAR1

• Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression. / 05.04.2016 / PubMed / Full text
• Type 1 interferons contribute to the clearance of senescent cell. / 2015 / PubMed / Full text

IGFBP4

• Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey. / 11.10.2019 / PubMed / Full text
• Age-Related Insulin-Like Growth Factor Binding Protein-4 Overexpression Inhibits Osteogenic Differentiation of Rat Mesenchymal Stem Cells. / 2017 / PubMed / Full text

IGHD

• Growth Hormone Deficiency: Health and Longevity. / 01.04.2019 / PubMed / Full text
• Lifetime, untreated isolated GH deficiency due to a GH-releasing hormone receptor mutation has beneficial consequences on bone status in older individuals, and does not influence their abdominal aorta calcification. / 09.2014 / PubMed / Full text

IGSF1

• Age-related gene and miRNA expression changes in airways of healthy individuals. / 06.03.2019 / PubMed / Full text
• The IGSF1 deficiency syndrome: characteristics of male and female patients. / 12.2013 / PubMed / Full text

IHH

• Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway. / 01.04.2020 / PubMed / Full text
• Transfection of the IHH gene into rabbit BMSCs in a simulated microgravity environment promotes chondrogenic differentiation and inhibits cartilage aging. / 27.09.2016 / PubMed / Full text

IL18

• p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. / 06.2020 / PubMed / Full text
• Aging and the Inflammasomes. / 2018 / PubMed / Full text

IL9

• A novel multi-marker discovery approach identifies new serum biomarkers for Parkinson's disease in older people: an EXosomes in PArkiNson Disease (EXPAND) ancillary study. / 10.2020 / PubMed / Full text
• Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text

ILDR1

• Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment. / 23.10.2019 / PubMed / Full text
• A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records. / 10.2016 / PubMed / Full text

ING1

• Impaired DNA demethylation of C/EBP sites causes premature aging. / 01.06.2018 / PubMed / Full text
• The tumor suppressor ING1b is a novel corepressor for the androgen receptor and induces cellular senescence in prostate cancer cells. / 06.2016 / PubMed / Full text

INPP5A

• DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

INSR

• Proteomics of Long-Lived Mammals. / 03.2020 / PubMed / Full text
• The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover. / 20.04.2017 / PubMed / Full text

IRF4

• Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text
• Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice. / 11.2017 / PubMed / Full text

IRGM

• SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
• Bt Cry1Ie Toxin Does Not Impact the Survival and Pollen Consumption of Chinese Honey Bees, Apis cerana cerana (Hymenoptera, Apidae). / 01.12.2016 / PubMed / Full text

ISG15

• White Matter Abnormalities Linked to Interferon, Stress Response, and Energy Metabolism Gene Expression Changes in Older HIV-Positive Patients on Antiretroviral Therapy. / 02.2020 / PubMed / Full text
• Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood. / 14.01.2019 / PubMed / Full text

ISL1

• Aging-relevant human basal forebrain cholinergic neurons as a cell model for Alzheimer's disease. / 21.10.2020 / PubMed / Full text
• Deterioration of the Medial Olivocochlear Efferent System Accelerates Age-Related Hearing Loss in Pax2-Isl1 Transgenic Mice. / 05.2016 / PubMed / Full text

ITGAM

• Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging. / 2019 / PubMed / Full text
• Transcriptomic analysis of purified human cortical microglia reveals age-associated changes. / 08.2017 / PubMed / Full text

ITGB2

• Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging. / 2019 / PubMed / Full text
• A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. / 2019 / PubMed / Full text

ITK

• Does Tetralogy of Fallot affect brain aging? A proof-of-concept study. / 2018 / PubMed / Full text
• Phenotypic characteristics of aged CD4 CD28 T lymphocytes are determined by changes in the whole-genome DNA methylation pattern. / 04.2017 / PubMed / Full text

JAK3

• Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. / 04.2018 / PubMed / Full text
• IL-15 enhances the antitumor effect of human antigen-specific CD8 T cells by cellular senescence delay. / 2016 / PubMed / Full text

KDM2B

• Identification of Structural Elements of the Lysine Specific Demethylase 2B CxxC Domain Associated with Replicative Senescence Bypass in Primary Mouse Cells. / 06.2020 / PubMed / Full text
• Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases. / 03.2016 / PubMed / Full text

KDM4B

• Inhibition of microRNA-27b-3p relieves osteoarthritis pain via regulation of KDM4B-dependent DLX5. / 09.2020 / PubMed / Full text
• Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases. / 03.2016 / PubMed / Full text

KDM4C

• KDM3A and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization. / 22.11.2019 / PubMed / Full text
• Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases. / 03.2016 / PubMed / Full text

KDM6B

• Histone demethylase KDM6B regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells. / 08.2019 / PubMed / Full text
• Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases. / 03.2016 / PubMed / Full text

KIFC3

• Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging. / 08.2018 / PubMed / Full text
• Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis. / 2016 / PubMed / Full text

KIR2DS5

• [The relationship between the polymorphism of immunity genes and both aging and age-related diseases]. / 07.2013 / PubMed / Full text
• 16(th) IHIW: immunogenetics of aging. / 02.2013 / PubMed / Full text

KISS1R

• Kisspeptin across the human lifespan:evidence from animal studies and beyond. / 06.2016 / PubMed / Full text
• Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. / 2015 / PubMed / Full text

KPNA2

• Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice. / 2019 / PubMed / Full text
• Upregulated Expression of Karyopherin α2 is Involved in Neuronal Apoptosis Following Intracerebral Hemorrhage in Adult Rats. / 07.2016 / PubMed / Full text

LAMA5

• The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. / 05.06.2018 / PubMed / Full text
• Association of the Laminin, Alpha 5 (LAMA5) rs4925386 with height and longevity in an elderly population from Southern Italy. / 04.2016 / PubMed / Full text

LAMC1

• Relation of size of seminal vesicles on ultrasound to premature ejaculation. / 09-10.2017 / PubMed / Full text
• Discovery and characterization of miRNA during cellular senescence in bone marrow-derived human mesenchymal stem cells. / 10.2014 / PubMed / Full text

LAT

• Is the combined auriculotherapy approach superior to magneto-auriculotherapy alone in aging males with lower urinary tract symptoms? A randomized controlled trial. / 16.01.2019 / PubMed / Full text
• Intra-couple Caregiving of Older Adults Living Apart Together: Commitment and Independence. / 09.2015 / PubMed / Full text

LATS2

• [Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. / 25.06.2019 / PubMed
• YAP1-LATS2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis. / 03.2019 / PubMed / Full text

LDHA

• Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16 inactivation. / 26.02.2018 / PubMed / Full text
• Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming. / 05.2018 / PubMed / Full text

LDLR

• Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice. / 08.2018 / PubMed / Full text
• Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice. / 15.01.2016 / PubMed / Full text

LEPR

• Age-related changes of leptin and leptin receptor variants in healthy elderly and long-lived adults. / 03.2015 / PubMed / Full text
• Functional polymorphisms of the leptin and leptin receptor genes are associated with longevity and with the risk of myocardial infarction and of type 2 diabetes mellitus. / 2014 / PubMed / Full text

LGI1

• Antibody-associated CNS syndromes without signs of inflammation in the elderly. / 03.10.2017 / PubMed / Full text
• Expression of NgR1-antagonizing proteins decreases with aging and cognitive decline in rat hippocampus. / 05.2013 / PubMed / Full text

LGR5

• Thyroid hormone activates Wnt/β-catenin signaling involved in adult epithelial development during intestinal remodeling in Xenopus laevis. / 08.2016 / PubMed / Full text
• Cancer stem cells in Helicobacter pylori infection and aging: Implications for gastric carcinogenesis. / 15.08.2014 / PubMed / Full text

LHCGR

• Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats. / 11.10.2020 / PubMed / Full text
• Association between the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) rs4073366 polymorphism and ovarian hyperstimulation syndrome during controlled ovarian hyperstimulation. / 25.07.2013 / PubMed / Full text

LIFR

• Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. / 15.03.2019 / PubMed / Full text
• Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction. / 12.2014 / PubMed / Full text

LIPA

• Modeling the cardiometabolic benefits of sleep in older women: exploring the 24-hour day. / 13.01.2020 / PubMed / Full text
• Influence of Habitual Physical Behavior - Sleeping, Sedentarism, Physical Activity - On Bone Health in Community-Dwelling Older People. / 2019 / PubMed / Full text

LOXL1

• A blackberry-dill extract combination synergistically increases skin elasticity. / 10.2020 / PubMed / Full text
• Methylation of LOXL1 Promoter by DNMT3A in Aged Human Skin Fibroblasts. / 04.2017 / PubMed / Full text

LRP4

• Multiple MuSK signaling pathways and the aging neuromuscular junction. / 13.07.2020 / PubMed / Full text
• Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4. / 10.10.2018 / PubMed / Full text

LRPPRC

• The loss of LRPPRC function induces the mitochondrial unfolded protein response. / 09.2015 / PubMed / Full text
• Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. / 16.12.2014 / PubMed / Full text

LRRN3

• Accelerated aging in HIV/AIDS: novel biomarkers of senescent human CD8 T cells. / 2013 / PubMed / Full text
• Transcriptomics of cortical gray matter thickness decline during normal aging. / 15.11.2013 / PubMed / Full text

LTB

• Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA DHA. / 06.2019 / PubMed / Full text
• Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis. / 11.2017 / PubMed / Full text

LTF

• Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text
• Effect of age on long-term facilitation and chemosensitivity during NREM sleep. / 15.11.2015 / PubMed / Full text

MALT1

• MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. / 29.04.2020 / PubMed / Full text
• MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging. / 2019 / PubMed / Full text

MAP1A

• SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
• Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging. / 21.05.2014 / PubMed / Full text

MAP1LC3B

• The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells. / 01.09.2018 / PubMed / Full text
• Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text

MAVS

• Spontaneous activation of a MAVS-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes. / 10.2017 / PubMed / Full text
• Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. / 02.08.2017 / PubMed / Full text

MBNL1

• Compound loss of muscleblind-like function in myotonic dystrophy. / 12.2013 / PubMed / Full text
• Dysfunction of protein homeostasis in myotonic dystrophies. / 09.2013 / PubMed / Full text

MC4R

• Melanocortin-4 receptor rs17782313 polymorphisms are associated with serum triglycerides in older Chinese women. / 2016 / PubMed / Full text
• Polymorphic variants of neurotransmitter receptor genes may affect sexual function in aging males: data from the HALS study. / 2013 / PubMed / Full text

MCM3

• Changes in MCM2-7 proteins at senescence. / 27.07.2019 / PubMed / Full text
• Up-regulation of MCM3 Relates to Neuronal Apoptosis After Traumatic Brain Injury in Adult Rats. / 05.2017 / PubMed / Full text

MCM4

• Hepatoprotective effects of hydroxysafflor yellow A in D-galactose-treated aging mice. / 15.08.2020 / PubMed / Full text
• Changes in MCM2-7 proteins at senescence. / 27.07.2019 / PubMed / Full text

MCM8

• Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. / 2017 / PubMed / Full text
• MCM8 and MCM9 Nucleotide Variants in Women With Primary Ovarian Insufficiency. / 01.02.2017 / PubMed / Full text

MCM9

• MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors. / 10.09.2019 / PubMed / Full text
• MCM8 and MCM9 Nucleotide Variants in Women With Primary Ovarian Insufficiency. / 01.02.2017 / PubMed / Full text

MDH1

• Oxidative Damage to the TCA Cycle Enzyme MDH1 Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. / 03.04.2020 / PubMed / Full text
• Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro. / 08.2019 / PubMed / Full text

MDM4

• In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text
• Germline genetics of the p53 pathway affect longevity in a gender specific manner. / 2014 / PubMed / Full text

ME1

• NADP-MALIC ENZYME 1 Affects Germination after Seed Storage in Arabidopsis thaliana. / 01.02.2019 / PubMed / Full text
• Down-regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy-induced senescence. / 04.2016 / PubMed / Full text

ME2

• A small-molecule inhibitor suppresses the tumor-associated mitochondrial NAD(P) -dependent malic enzyme (ME2) and induces cellular senescence. / 21.08.2015 / PubMed / Full text
• Down-regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy-induced senescence. / 04.2016 / PubMed / Full text

MEF2D

• Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency. / 01.07.2017 / PubMed / Full text
• Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem. / 2014 / PubMed / Full text

MEFV

• The grandfather's fever. / 02.2020 / PubMed / Full text
• E148Q MEFV mutation carriage and longevity in individuals of Ashkenazi origin. / 07.2013 / PubMed / Full text

MEIS1

• Down-regulation of MEIS1 promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes. / 06.2019 / PubMed / Full text
• Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

MELK

• MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells. / 02.10.2015 / PubMed / Full text
• Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells. / 16.08.2013 / PubMed / Full text

MEOX2

• Reduced expression of microRNA-130a promotes endothelial cell senescence and age-dependent impairment of neovascularization. / 26.05.2020 / PubMed / Full text
• Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease. / 06.2016 / PubMed / Full text

MGAT1

• Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence. / 28.12.2016 / PubMed / Full text
• Transcriptional and biochemical responses of monoacylglycerol acyltransferase-mediated oil synthesis and associated senescence-like responses in Nicotiana benthamiana. / 2014 / PubMed / Full text

MIB1

• MIB1-mediated degradation of WRN promotes cellular senescence in response to camptothecin treatment. / 09.2020 / PubMed / Full text
• Immunohistochemical detection of senescence markers in human sarcomas. / 02.2020 / PubMed / Full text

MICA

• Derivation and Validation of a Geriatric-Sensitive Perioperative Cardiac Risk Index. / 16.11.2017 / PubMed / Full text
• NKG2D ligands mediate immunosurveillance of senescent cells. / 02.2016 / PubMed / Full text

MLH1

• The somatic mutation landscape of the human body. / 24.12.2019 / PubMed / Full text
• RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text

MMP10

• Astrocyte senescence may drive alterations in GFAPα, [[CDKN2A]] p14 , and TAU3 transcript expression and contribute to cognitive decline. / 10.2019 / PubMed / Full text
• Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates. / 05.2016 / PubMed / Full text

MMP14

• Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells. / 12.2017 / PubMed / Full text
• Enhanced tissue regeneration potential of juvenile articular cartilage. / 11.2013 / PubMed / Full text

MMP8

• [Investigation of signal molecules in saliva: prospects of application for diagnostics of myocardial infarction and the aging rate of different age people.] / 2019 / PubMed
• Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates. / 05.2016 / PubMed / Full text

MS4A6E

• Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
• Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. / 04.2016 / PubMed / Full text

MSH6

• RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text
• DNA mismatch repair system: repercussions in cellular homeostasis and relationship with aging. / 2012 / PubMed / Full text

MT2A

• Metallothionein Prevents Age-Associated Cardiomyopathy via Inhibiting NF-κB Pathway Activation and Associated Nitrative Damage to 2-OGD. / 10.12.2016 / PubMed / Full text
• Metallothioneins and renal ageing. / 09.2016 / PubMed / Full text

MTM1

• Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice. / 20.03.2019 / PubMed / Full text
• Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy. / 19.11.2018 / PubMed / Full text

MTRR

• One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults. / 12.2019 / PubMed / Full text
• [Clinical and genetic characteristics of long-livers in Moscow region]. / 2013 / PubMed

MUC1

• Sensitivity of neoplastic cells to senescence unveiled under standard cell culture conditions. / 05.2015 / PubMed
• Serum KL-6 concentrations are associated with molecular sizes and efflux behavior of KL-6/MUC1 in healthy subjects. / 23.09.2013 / PubMed / Full text

MUC2

• KLF4 deletion alters gastric cell lineage and induces MUC2 expression. / 09.06.2016 / PubMed / Full text
• Early intestinal development and mucin transcription in the young poult with probiotic and mannan oligosaccharide prebiotic supplementation. / 05.2016 / PubMed / Full text

MX1

• White Matter Abnormalities Linked to Interferon, Stress Response, and Energy Metabolism Gene Expression Changes in Older HIV-Positive Patients on Antiretroviral Therapy. / 02.2020 / PubMed / Full text
• Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection. / 10.11.2018 / PubMed / Full text

MYBL2

• A multidimensional systems biology analysis of cellular senescence in aging and disease. / 07.04.2020 / PubMed / Full text
• Molecular mechanism of G arrest and cellular senescence induced by LEE011, a novel CDK4/CDK6 inhibitor, in leukemia cells. / 2017 / PubMed / Full text

MYBPC3

• Compound heterozygosity deteriorates phenotypes of hypertrophic cardiomyopathy with founder MYBPC3 mutation: evidence from patients and zebrafish models. / 01.12.2014 / PubMed / Full text
• Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text

MYOCD

• Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a. / 01.11.2016 / PubMed / Full text
• Transplantation of mesenchymal cells rejuvenated by the overexpression of telomerase and myocardin promotes revascularization and tissue repair in a murine model of hindlimb ischemia. / 13.09.2013 / PubMed / Full text

MYOD1

• Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice. / 08.2016 / PubMed / Full text
• Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model. / 03.2016 / PubMed / Full text

NAT2

• Lifestyle and clinical determinants of skin autofluorescence in a population-based cohort study. / 05.2016 / PubMed / Full text
• The ultra-slow NAT2*6A haplotype is associated with reduced higher cognitive functions in an elderly study group. / 12.2015 / PubMed / Full text

NAV2

• Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text
• Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text

NCAM1

• Resistance Training Enhances Skeletal Muscle Innervation Without Modifying the Number of Satellite Cells or their Myofiber Association in Obese Older Adults. / 10.2016 / PubMed / Full text
• Human skin keratinocytes can be reprogrammed to express neuronal genes and proteins after a single treatment with decitabine. / 06.2013 / PubMed / Full text

NDNF

• Effect of neuron-derived neurotrophic factor on rejuvenation of human adipose-derived stem cells for cardiac repair after myocardial infarction. / 09.2019 / PubMed / Full text
• Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury. / 12.2017 / PubMed / Full text

NDUFS1

• Mapping the protein phosphorylation sites in human mitochondrial complex I (NADH: Ubiquinone oxidoreductase): A bioinformatics study with implications for brain aging and neurodegeneration. / 01.2019 / PubMed / Full text
• Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. / 04.2014 / PubMed / Full text

NECTIN2

• Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text
• Apolipoprotein E region molecular signatures of Alzheimer's disease. / 08.2018 / PubMed / Full text

NEDD4

• Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis. / 25.08.2020 / PubMed / Full text
• Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate. / 09.05.2017 / PubMed / Full text

NEFM

• Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age. / 06.2019 / PubMed / Full text
• The Alzheimer's disease transcriptome mimics the neuroprotective signature of IGF-1 receptor-deficient neurons. / 01.07.2017 / PubMed / Full text

NEIL1

• NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress. / 09.2019 / PubMed / Full text
• Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation. / 09.10.2015 / PubMed / Full text

NEIL2

• Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals. / 04.2020 / PubMed / Full text
• Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation. / 09.10.2015 / PubMed / Full text

NEK2

• A multidimensional systems biology analysis of cellular senescence in aging and disease. / 07.04.2020 / PubMed / Full text
• Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma. / 21.11.2018 / PubMed / Full text

NEO1

• Neogenin-1 distinguishes between myeloid-biased and balanced [i]Hoxb5[/i] mouse long-term hematopoietic stem cells. / 10.12.2019 / PubMed / Full text
• Ionizing radiation reduces ADAM10 expression in brain microvascular endothelial cells undergoing stress-induced senescence. / 04.2017 / PubMed / Full text

NFATC1

• Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. / 02.10.2017 / PubMed / Full text
• Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS. / 25.05.2017 / PubMed / Full text

NFIB

• Cell-type-specific expression of NFIX in the developing and adult cerebellum. / 07.2017 / PubMed / Full text
• Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/NFIB. / 03.11.2016 / PubMed / Full text

NHLRC1

• DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing. / 05.2017 / PubMed / Full text
• Loss of GABAergic cortical neurons underlies the neuropathology of Lafora disease. / 28.01.2014 / PubMed / Full text

NLRP1

• NADPH oxidase 2-mediated NLRP1 inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro. / 04.2019 / PubMed / Full text
• Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol. / 2014 / PubMed / Full text

NLRP12

• Persistent DNA damage-induced NLRP12 improves hematopoietic stem cell function. / 21.05.2020 / PubMed / Full text
• Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa. / 02.2016 / PubMed / Full text

NLRX1

• NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells. / 26.02.2018 / PubMed / Full text
• The expression of NLRX1 in C57BL/6 mice cochlear hair cells: Possible relation to aging- and neomycin-induced deafness. / 11.03.2016 / PubMed / Full text

NMB

• Deceased donor kidney allocation: an economic evaluation of contemporary longevity matching practices. / 09.10.2020 / PubMed / Full text
• Asleep versus awake: does it matter?: Pediatric regional block complications by patient state: a report from the Pediatric Regional Anesthesia Network. / 07-08.2014 / PubMed / Full text

NME8

• Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
• Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. / 04.2016 / PubMed / Full text

NMNAT1

• ADNP differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. / 06.2019 / PubMed / Full text
• Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

NMNAT2

• NMNAT2-mediated NAD generation is essential for quality control of aged oocytes. / 06.2019 / PubMed / Full text
• Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy. / 03.10.2017 / PubMed / Full text

NMS

• Uncontrolled Diabetes as an Associated Factor with Dynapenia in Adults Aged 50 Years or Older: Sex Differences. / 22.05.2020 / PubMed / Full text
• Neonatal stress affects the aging trajectory of female rats on the endocrine, temperature, and ventilatory responses to hypoxia. / 01.04.2015 / PubMed / Full text

NNMT

• Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle. / 05.2019 / PubMed / Full text
• Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy. / 09.2018 / PubMed / Full text

NONO

• Physiological levels of thrombospondin-1 decrease NO-dependent vasodilation in coronary microvessels from aged rats. / 01.06.2016 / PubMed / Full text
• The effects of aging on the functional and structural properties of the rat basilar artery. / 01.06.2014 / PubMed / Full text

NOP10

• Pseudouridylation defect due to [i]DKC1[/i] and [i]NOP10[/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. / 30.06.2020 / PubMed / Full text
• Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. / 04.2018 / PubMed / Full text

NPTX2

• Evaluation of DNA methylation markers and their potential to predict human aging. / 08.2015 / PubMed / Full text
• Developing a DNA methylation assay for human age prediction in blood and bloodstain. / 07.2015 / PubMed / Full text

NPW

• Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study. / 09.2020 / PubMed / Full text
• Neuropeptide W modulation of gastric vagal afferent mechanosensitivity: Impact of age and sex. / 09.2015 / PubMed / Full text

NPY1R

• NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? / 2015 / PubMed / Full text
• Vulnerability imposed by diet and brain trauma for anxiety-like phenotype: implications for post-traumatic stress disorders. / 2013 / PubMed / Full text

NPY5R

• Effects of age on feeding response: Focus on the rostral C1 neuron and its glucoregulatory proteins. / 01.2020 / PubMed / Full text
• NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? / 2015 / PubMed / Full text

NR3C1

• Glucocorticoid receptor (NR3C1) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians. / 02.2019 / PubMed / Full text
• Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain. / 01.04.2018 / PubMed / Full text

NRL

• Development of a cyclophosphamide stress test to predict resilience to aging in mice. / 12.2020 / PubMed / Full text
• A Spontaneous Aggressive ERα Mammary Tumor Model Is Driven by Kras Activation. / 06.08.2019 / PubMed / Full text

NRM

• Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation. / 12.2019 / PubMed / Full text
• Who is the better donor for older hematopoietic transplant recipients: an older-aged sibling or a young, matched unrelated volunteer? / 28.03.2013 / PubMed / Full text

NRP1

• APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease. / 03.2020 / PubMed / Full text
• Neuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged mice. / 2015 / PubMed / Full text

NRXN1

• Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex. / 01.01.2017 / PubMed / Full text
• Neurexin 1 ([[NRXN1]]) splice isoform expression during human neocortical development and aging. / 05.2016 / PubMed / Full text

NRXN3

• Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text
• Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex. / 01.01.2017 / PubMed / Full text

NTF4

• Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles. / 13.06.2017 / PubMed / Full text
• Enhancement of aging rat laryngeal muscles with endogenous growth factor treatment. / 05.2016 / PubMed / Full text

NTRK2

• The Role of BDNF in Age-Dependent Changes of Excitatory and Inhibitory Synaptic Markers in the Human Prefrontal Cortex. / 12.2016 / PubMed / Full text
• Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer's disease animal model. / 2013 / PubMed / Full text

OAT

• Opioid agonist treatment reduces losses in quality of life and quality-adjusted life expectancy in heroin users: Evidence from real world data. / 01.08.2019 / PubMed / Full text
• Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats. / 02.2019 / PubMed / Full text

OMD

• Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. / 06.02.2019 / PubMed / Full text
• Digestive capacity in weanling and mature horses. / 05.2013 / PubMed / Full text

OPTN

• Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3. / 04.11.2020 / PubMed / Full text
• Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. / 24.02.2016 / PubMed / Full text

ORAI1

• Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis. / 02.2020 / PubMed / Full text
• Calcium Dynamics of Ex Vivo Long-Term Cultured CD8 T Cells Are Regulated by Changes in Redox Metabolism. / 2016 / PubMed / Full text

P2RX7

• The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text
• A rare functional haplotype of the P2RX4 and P2RX7 genes leads to loss of innate phagocytosis and confers increased risk of age-related macular degeneration. / 04.2013 / PubMed / Full text

PALB2

• 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. / 02.01.2020 / PubMed / Full text
• A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer. / 04.2017 / PubMed / Full text

PAX5

• Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low PAX5. / 08.2018 / PubMed / Full text
• Developmental expression of B cell molecules in equine lymphoid tissues. / 01.2017 / PubMed / Full text

PAX6

• Pbx1 is required for adult subventricular zone neurogenesis. / 01.07.2016 / PubMed / Full text
• Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. / 03.2015 / PubMed / Full text

PBX1

• Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence. / 10.2020 / PubMed / Full text
• Pbx1 is required for adult subventricular zone neurogenesis. / 01.07.2016 / PubMed / Full text

PCDH10

• Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. / 12.2017 / PubMed / Full text
• PCDH10, a novel p53 transcriptional target in regulating cell migration. / 2015 / PubMed / Full text

PDCD4

• Petal abscission in roses is associated with the activation of a truncated version of the animal PDCD4 homologue, RbPCD1. / 11.2019 / PubMed / Full text
• PDCD4 Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression. / 2018 / PubMed / Full text

PDE2A

• TAK-915, a phosphodiesterase 2A inhibitor, ameliorates the cognitive impairment associated with aging in rodent models. / 30.12.2019 / PubMed / Full text
• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDE3A

• Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. / 07.2015 / PubMed / Full text
• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDE5A

• Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass. / 23.06.2020 / PubMed / Full text
• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDE9A

• Identification of new PDE9A isoforms and how their expression and subcellular compartmentalization in the brain change across the life span. / 05.2018 / PubMed / Full text
• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDGFB

• Skin-resident stem cells and wound healing. / 2017 / PubMed / Full text
• The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease. / 10.2015 / PubMed / Full text

PDHB

• Oxidative Damage to the TCA Cycle Enzyme MDH1 Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. / 03.04.2020 / PubMed / Full text
• Neuron-specific knockdown of Drosophila PDHB induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting. / 15.05.2018 / PubMed / Full text

PDK2

• Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training. / 01.07.2016 / PubMed / Full text
• Effects of Exercise Training on Regulation of Skeletal Muscle Glucose Metabolism in Elderly Men. / 07.2015 / PubMed / Full text

PDK4

• Putrescine delays postovulatory aging of mouse oocytes by upregulating PDK4 expression and improving mitochondrial activity. / 16.12.2018 / PubMed / Full text
• Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training. / 01.07.2016 / PubMed / Full text

PENK

• Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study. / 09.02.2016 / PubMed / Full text
• Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs. / 06.2014 / PubMed / Full text

PES1

• Transcription factor RD26 is a key regulator of metabolic reprogramming during dark-induced senescence. / 06.2018 / PubMed / Full text
• The Plastoglobule-Localized Metallopeptidase PGM48 Is a Positive Regulator of Senescence in Arabidopsis thaliana. / 12.2016 / PubMed / Full text

PFKFB3

• DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system. / 05.2018 / PubMed / Full text
• Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity. / 15.05.2015 / PubMed / Full text

PGAM1

• Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text
• The aged testis. A good model to find proteins involved in age-related changes of testis by proteomic analysis. / 01-02.2014 / PubMed

PGR

• Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain. / 01.04.2018 / PubMed / Full text
• Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. / 2015 / PubMed / Full text

PHB2

• Prohibitin-2 is a novel regulator of p21 induced by depletion of γ-glutamylcyclotransferase. / 29.01.2018 / PubMed / Full text
• Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. / 12.01.2017 / PubMed / Full text

PI4KB

• Differential DNA Methylation in Relation to Age and Health Risks of Obesity. / 24.07.2015 / PubMed / Full text
• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

PIEZO1

• Niche stiffness underlies the ageing of central nervous system progenitor cells. / 09.2019 / PubMed / Full text
• On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, PIEZO1, and Gardos Channels. / 2017 / PubMed / Full text

PIK3R2

• The senescent status of endothelial cells affects proliferation, inflammatory profile and SOX2 expression in bone marrow-derived mesenchymal stem cells. / 06.2019 / PubMed / Full text
• Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. / 01.2016 / PubMed / Full text

PKP2

• Molecular disturbance underlies to arrhythmogenic cardiomyopathy induced by transgene content, age and exercise in a truncated PKP2 mouse model. / 01.09.2016 / PubMed / Full text
• Age-dependent clinical and genetic characteristics in Japanese patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia. / 2013 / PubMed / Full text

PLA2G6

• Mutations in the Drosophila homolog of human PLA2G6 give rise to age-dependent loss of psychomotor activity and neurodegeneration. / 13.02.2018 / PubMed / Full text
• iPLA2β knockout mouse, a genetic model for progressive human motor disorders, develops age-related neuropathology. / 08.2014 / PubMed / Full text

PLD3

• Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text
• Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text

PLK1

• Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text
• Downregulation of Polo-like kinase 1 induces cellular senescence in human primary cells through a p53-dependent pathway. / 10.2013 / PubMed / Full text

PLK4

• A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence. / 05.2020 / PubMed / Full text
• Differential expression of AURKA/PLK4 in quiescence and senescence of osteosarcoma U2OS cells. / 04.2020 / PubMed / Full text

PMP22

• Role of microRNAs in senescence and its contribution to peripheral neuropathy in the arsenic exposed population of West Bengal, India. / 02.2018 / PubMed / Full text
• A molecular signature predictive of indolent prostate cancer. / 11.09.2013 / PubMed / Full text

POLD3

• POLD3 Is Haploinsufficient for DNA Replication in Mice. / 01.09.2016 / PubMed / Full text
• POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies. / 15.09.2016 / PubMed / Full text

POLG2

• An N-Ethyl-N-Nitrosourea (ENU)-Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice. / 03.2019 / PubMed / Full text
• Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text

PPARD

• PPARD 294C overrepresentation in general and long-lived population in China Bama longevity area and unique relationships between PPARD 294T/C polymorphism and serum lipid profiles. / 07.03.2015 / PubMed / Full text
• [Genotype and allele frequencies of UCP and PPAR gene families in residents of besieged Leningrad and in the control group]. / 2014 / PubMed

PPM1D

• Detectible mosaic truncating PPM1D mutations, age and breast cancer risk. / 06.2019 / PubMed / Full text
• Age-related remodelling of oesophageal epithelia by mutated cancer drivers. / 01.2019 / PubMed / Full text

PPP3CB

• The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text
• Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text

PPY

• Delta Cell Hyperplasia in Adult Goto-Kakizaki (GK/MolTac) Diabetic Rats. / 2015 / PubMed / Full text
• Blood Protein Markers of Neocortical Amyloid-β Burden: A Candidate Study Using SOMAscan Technology. / 2015 / PubMed / Full text

PRF1

• Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. / 01.2016 / PubMed / Full text
• Gene expression markers of age-related inflammation in two human cohorts. / 10.2015 / PubMed / Full text

PRG4

• Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis. / 08.02.2018 / PubMed / Full text
• Age-related changes in structure and extracellular matrix protein expression levels in rat tendons. / 12.2013 / PubMed / Full text

PRKAA2

• Study on the effect of CaMKKβ-mediated AMPK activation on the glycolysis and the quality of different altitude postmortem bovines longissimus muscle. / 11.2019 / PubMed / Full text
• Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone. / 07.2014 / PubMed / Full text

PRMT7

• Regenerating muscle with arginine methylation. / 27.05.2017 / PubMed / Full text
• PRMT7 Preserves Satellite Cell Regenerative Capacity. / 16.02.2016 / PubMed / Full text

PRMT8

• Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons. / 29.08.2018 / PubMed / Full text
• Novel Protein Arginine Methyltransferase 8 Isoform Is Essential for Cell Proliferation. / 09.2016 / PubMed / Full text

PROX1

• Molecular control of two novel migratory paths for CGE-derived interneurons in the developing mouse brain. / 15.05.2016 / PubMed / Full text
• PROX1: a lineage tracer for cortical interneurons originating in the lateral/caudal ganglionic eminence and preoptic area. / 2013 / PubMed / Full text

PSMB8

• [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text
• Assessment of the risk of blastomere biopsy during preimplantation genetic diagnosis in a mouse model: reducing female ovary function with an increase in age by proteomics method. / 06.12.2013 / PubMed / Full text

PTH1R

• Bone-remodeling transcript levels are independent of perching in end-of-lay white leghorn chickens. / 23.01.2015 / PubMed / Full text
• Variation in the [[PTH2R]] gene is associated with age-related degenerative changes in the lumbar spine. / 01.2015 / PubMed / Full text

PTK7

• Innate and adaptive immune dysregulation in critically ill ICU patients. / 05.07.2018 / PubMed / Full text
• Heterogeneity in thymic emigrants: implications for thymectomy and immunosenescence. / 2013 / PubMed / Full text

PTPN1

• The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text
• Leptin and leptin-related gene polymorphisms, obesity, and influenza A/H1N1 vaccine-induced immune responses in older individuals. / 07.02.2014 / PubMed / Full text

PTTG1

• [Down-regulated PTTG1 expression promotes the senescence of human prostate cancer LNCaP-AI]. / 03.2019 / PubMed
• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

PUM2

• PUMILIO hyperactivity drives premature aging of [i]Norad[/i]-deficient mice. / 08.02.2019 / PubMed / Full text
• The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging. / 21.02.2019 / PubMed / Full text

PYCR1

• A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals POSTN As a New Element in Proline Metabolic Disorder. / 12.2018 / PubMed / Full text
• Sublethal endoplasmic reticulum stress caused by the mutation of immunoglobulin heavy chain-binding protein induces the synthesis of a mitochondrial protein, pyrroline-5-carboxylate reductase 1. / 01.2017 / PubMed / Full text

RAD51B

• Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human RAD52 gene in a cardiovascular cohort. / 10.2017 / PubMed / Full text
• [What's new in dermatological research?]. / 12.2012 / PubMed / Full text

RAG1

• T cell senescence accelerates Angiotensin II-induced target organ damage. / 12.02.2020 / PubMed / Full text
• Aged murine hematopoietic stem cells drive aging-associated immune remodeling. / 09.08.2018 / PubMed / Full text

RAG2

• Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation. / 2020 / PubMed / Full text
• Both retention and recirculation contribute to long-lived regulatory T-cell accumulation in the thymus. / 09.2014 / PubMed / Full text

RASGRP1

• Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. / 12.2017 / PubMed / Full text
• PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling. / 13.11.2014 / PubMed / Full text

RECQL5

• RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins. / 01.2016 / PubMed / Full text
• Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice. / 15.05.2014 / PubMed / Full text

RNF168

• 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. / 02.01.2020 / PubMed / Full text
• PML nuclear bodies are recruited to persistent DNA damage lesions in an RNF168-53BP1 dependent manner and contribute to DNA repair. / 06.2019 / PubMed / Full text

RPIA

• Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming. / 20.08.2019 / PubMed / Full text
• Ribose-5-phosphate isomerase A regulates hepatocarcinogenesis via PP2A and ERK signaling. / 01.07.2015 / PubMed / Full text

RRM1

• α-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1. / 08.2019 / PubMed / Full text
• GBM-associated mutations and altered protein expression are more common in young patients. / 25.10.2016 / PubMed / Full text

RXRG

• Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. / 2017 / PubMed / Full text
• Genome wide association study of age at menarche in the Japanese population. / 2013 / PubMed / Full text

S100A12

• Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model. / 06.07.2018 / PubMed / Full text
• Evaluation of serum biochemical marker concentrations and survival time in dogs with protein-losing enteropathy. / 01.01.2015 / PubMed / Full text

S100A6

• Sex differences in distribution of cannabinoid receptors (CB1 and CB2), S100A6 and CacyBP/SIP in human ageing hearts. / 27.11.2018 / PubMed / Full text
• S100A6 (calcyclin) is a novel marker of neural stem cells and astrocyte precursors in the subgranular zone of the adult mouse hippocampus. / 01.2014 / PubMed / Full text

S1PR3

• Sexual dimorphism of metabolic and vascular dysfunction in aged mice and those lacking the sphingosine 1-phosphate receptor 3. / 01.12.2017 / PubMed / Full text
• Impact of Age and Polytherapy on Fingolimod Induced Bradycardia: a Preclinical Study. / 03.2017 / PubMed / Full text

SAA1

• Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells. / 2018 / PubMed / Full text
• Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients. / 2017 / PubMed / Full text

SALL1

• SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex. / 06.04.2018 / PubMed / Full text
• Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. / 12.2017 / PubMed / Full text

SCGN

• Detection and evaluation of DNA methylation markers found at SCGN and KLF14 loci to estimate human age. / 11.2017 / PubMed / Full text
• DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing. / 05.2017 / PubMed / Full text

SCN2B

• MicroRNA‑449a regulates the progression of brain aging by targeting SCN2B in SAMP8 mice. / 04.2020 / PubMed / Full text
• Sodium Channel Voltage-Gated Beta 2 Plays a Vital Role in Brain Aging Associated with Synaptic Plasticity and Expression of COX5A and FGF-2. / 03.2016 / PubMed / Full text

SCN5A

• [Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug]. / 2018 / PubMed / Full text
• Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. / 06.2014 / PubMed / Full text

SCO2

• Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients. / 03.09.2019 / PubMed / Full text
• Role of SCOX in determination of Drosophila melanogaster lifespan. / 2014 / PubMed / Full text

SDC4

• Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. / 01.10.2017 / PubMed / Full text
• Metabolism and successful aging: Polymorphic variation of syndecan-4 (SDC4) gene associate with longevity and lipid profile in healthy elderly Italian subjects. / 09.2015 / PubMed / Full text

SDHC

• Endogenous reactive oxygen species cause astrocyte defects and neuronal dysfunctions in the hippocampus: a new model for aging brain. / 02.2017 / PubMed / Full text
• Long-term prognosis of patients with pediatric pheochromocytoma. / 02.2014 / PubMed / Full text

SERPINB2

• Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes. / 15.01.2020 / PubMed / Full text
• An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through SERPINB2. / 03.07.2019 / PubMed / Full text

SESN2

• Copy Number Alterations in Papillary Thyroid Carcinomas: Does Loss of [i]SESN2[/i] Have a Role in Age-related Different Prognoses? / 09-10.2020 / PubMed / Full text
• Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea. / 11.10.2017 / PubMed / Full text

SESN3

• Autophagy mediators (FOXO1, SESN3 and TSC2) in Lewy body disease and aging. / 25.09.2018 / PubMed / Full text
• Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration. / 12.2017 / PubMed / Full text

SFRP2

• [Role and alterations of DNA methylation during the aging and cancer]. / 01.2018 / PubMed / Full text
• Thyroid hormone activates Wnt/β-catenin signaling involved in adult epithelial development during intestinal remodeling in Xenopus laevis. / 08.2016 / PubMed / Full text

SGK1

• Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells. / 05.2020 / PubMed / Full text
• The cell survival kinase SGK1 and its targets FOXO3a and NDRG1 in aged human brain. / 10.2013 / PubMed / Full text

SIX3

• CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type. / 30.11.2018 / PubMed / Full text
• Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function. / 10.05.2016 / PubMed / Full text

SLC13A5

• INDY-A New Link to Metabolic Regulation in Animals and Humans. / 2017 / PubMed / Full text
• The role of INDY in metabolism, health and longevity. / 2015 / PubMed / Full text

SLC16A7

• Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach. / 23.10.2020 / PubMed / Full text
• The SLC16 gene family - structure, role and regulation in health and disease. / 04-06.2013 / PubMed / Full text

SLC19A1

• Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer. / 30.03.2018 / PubMed / Full text
• Association of MTHFR, SLC19A1 Genetic Polymorphism, Serum Folate, Vitamin B and Hcy Status with Cognitive Functions in Chinese Adults. / 24.10.2016 / PubMed / Full text

SLC24A4

• Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
• Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. / 04.2016 / PubMed / Full text

SLC25A24

• De Novo Mutations in SLC25A24 Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise. / 02.11.2017 / PubMed / Full text
• De Novo Mutations in SLC25A24 Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction. / 02.11.2017 / PubMed / Full text

SLC26A2

• Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis. / 01.2020 / PubMed / Full text
• Alteration of proteoglycan sulfation affects bone growth and remodeling. / 05.2013 / PubMed / Full text

SLC2A4

• Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity. / 02.08.2020 / PubMed / Full text
• Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

SLC2A9

• ABCG2 rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population. / 17.03.2020 / PubMed / Full text
• MicroRNA-Based Linkage between Aging and Cancer: from Epigenetics View Point. / 07-09.2016 / PubMed / Full text

SLC6A3

• A variable number of tandem repeats in the 3'-untranslated region of the dopamine transporter modulates striatal function during working memory updating across the adult age span. / 08.2015 / PubMed / Full text
• Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. / 2015 / PubMed / Full text

SLC7A11

• SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes. / 28.10.2017 / PubMed / Full text
• Comprehensive Analysis of Interaction Networks of Telomerase Reverse Transcriptase with Multiple Bioinformatic Approaches: Deep Mining the Potential Functions of Telomere and Telomerase. / 08.2017 / PubMed / Full text

SLN

• Completion Lymph Node Dissection or Observation for Melanoma Sentinel Lymph Node Metastases: A Decision Analysis. / 09.2016 / PubMed / Full text
• Age differences in brain activity related to unsuccessful declarative memory retrieval. / 01.07.2015 / PubMed / Full text

SMAD1

• TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands. / 26.11.2019 / PubMed / Full text
• BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence. / 15.11.2016 / PubMed / Full text

SMAD7

• Forkhead Box Protein 1 (FoxO1) Inhibits Accelerated β Cell Aging in Pancreas-specific SMAD7 Mutant Mice. / 24.02.2017 / PubMed / Full text
• Granulosa cell function and oocyte competence: Super-follicles, super-moms and super-stimulation in cattle. / 09.2014 / PubMed / Full text

SMARCA4

• Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration. / 09.2020 / PubMed / Full text
• GBM-associated mutations and altered protein expression are more common in young patients. / 25.10.2016 / PubMed / Full text

SMO

• Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text
• Silybum marianum oil attenuates oxidative stress and ameliorates mitochondrial dysfunction in mice treated with D-galactose. / 01.2014 / PubMed / Full text

SMOX

• Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine. / 14.02.2018 / PubMed / Full text
• Haemocytes control stem cell activity in the Drosophila intestine. / 06.2015 / PubMed / Full text

SMPD1

• Alterations in Lipid Profile of the Aging Kidney Identified by MALDI Imaging Mass Spectrometry. / 05.07.2019 / PubMed / Full text
• Rare lysosomal enzyme gene SMPD1 variant (p.R591C) associates with Parkinson's disease. / 12.2013 / PubMed / Full text

SNCB

• Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. / 08.2019 / PubMed / Full text
• Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro. / 05.2018 / PubMed / Full text

SOCS2

• Suppressor of Cytokine Signalling 2 (SOCS2) Regulates Numbers of Mature Newborn Adult Hippocampal Neurons and Their Dendritic Spine Maturation. / 07.2017 / PubMed / Full text
• Age-independent effects of hyaluronan amide derivative and growth hormone on human osteoarthritic chondrocytes. / 11.2015 / PubMed / Full text

SPARCL1

• Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment. / 18.06.2019 / PubMed / Full text
• SPARCL1 Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging. / 2018 / PubMed / Full text

SPN

• Parkinson's disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging. / 19.02.2020 / PubMed / Full text
• [Identification of single nucleotide polymorphisms in centenarians]. / 05-06.2016 / PubMed / Full text

SPON1

• APOE influences working memory in non-demented elderly through an interaction with SPON1 rs2618516. / 07.2018 / PubMed / Full text
• HYDRA: Revealing heterogeneity of imaging and genetic patterns through a multiple max-margin discriminative analysis framework. / 15.01.2017 / PubMed / Full text

SREBF2

• The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators. / 29.09.2020 / PubMed / Full text
• White Matter Abnormalities Linked to Interferon, Stress Response, and Energy Metabolism Gene Expression Changes in Older HIV-Positive Patients on Antiretroviral Therapy. / 02.2020 / PubMed / Full text

SRR

• Mediterranean diet and its components in relation to all-cause mortality: meta-analysis. / 11.2018 / PubMed / Full text
• Genetic Biomarkers on Age-Related Cognitive Decline. / 2017 / PubMed / Full text

SSTR1

• Expression and localization of somatostatin receptor types 3, 4 and 5 in the wild-type, SSTR1 and SSTR1/SSTR2 knockout mouse cochlea. / 12.2014 / PubMed / Full text
• Upregulated expression of SSTR1 is involved in neuronal apoptosis and is coupled to the reduction of bcl-2 following intracerebral hemorrhage in adult rats. / 10.2014 / PubMed / Full text

ST6GAL1

• Glycobiology of Aging. / 2018 / PubMed / Full text
• Identification of novel plasma glycosylation-associated markers of aging. / 16.02.2016 / PubMed / Full text

STAR

• Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs. / 01.03.2017 / PubMed / Full text
• Role of the steroidogenic acute regulatory protein in health and disease. / 01.2016 / PubMed / Full text

STAT4

• Neonatal T Follicular Helper Cells Are Lodged in a Pre-T Follicular Helper Stage Favoring Innate Over Adaptive Germinal Center Responses. / 2019 / PubMed / Full text
• RNA-Seq analysis reveals new evidence for inflammation-related changes in aged kidney. / 24.05.2016 / PubMed / Full text

STAT5A

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
• SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes. / 28.10.2017 / PubMed / Full text

STK3

• Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. / 11.12.2018 / PubMed / Full text
• Organ-specific alteration in caspase expression and STK3 proteolysis during the aging process. / 11.2016 / PubMed / Full text

SURF1

• Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice. / 08.2018 / PubMed / Full text
• Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses. / 01.09.2014 / PubMed / Full text

SV2A

• Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging. / 01.10.2018 / PubMed / Full text
• Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. / 10.2018 / PubMed / Full text

SYNC

• Alpha-synuclein expression patterns in the colonic submucosal plexus of the aging Fischer 344 rat: implications for biopsies in aging and neurodegenerative disorders? / 09.2013 / PubMed / Full text
• Macrophages are unsuccessful in clearing aggregated alpha-synuclein from the gastrointestinal tract of healthy aged Fischer 344 rats. / 04.2013 / PubMed / Full text

SYNJ1

• Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer's Disease. / 05.06.2018 / PubMed / Full text
• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

TACR3

• Association of a neurokinin 3 receptor polymorphism with the anterior basal forebrain. / 06.2015 / PubMed / Full text
• Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism. / 10.09.2013 / PubMed / Full text

TAS2R16

• Taste receptor polymorphisms and longevity: a systematic review and meta-analysis. / 10.11.2020 / PubMed / Full text
• Taste receptors, innate immunity and longevity: the case of TAS2R16 gene. / 2019 / PubMed / Full text

TBC1D4

• Effects of Exercise Training on Regulation of Skeletal Muscle Glucose Metabolism in Elderly Men. / 07.2015 / PubMed / Full text
• AMPK and insulin action--responses to ageing and high fat diet. / 2013 / PubMed / Full text

TBC1D5

• TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry. / 09.06.2020 / PubMed / Full text
• Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling. / 02.09.2019 / PubMed / Full text

TBX21

• Association of Epigenetic Age and p16INK4a With Markers of T-Cell Composition in a Healthy Cohort. / 13.11.2020 / PubMed / Full text
• [Study of gene expression of transcription factors T cells during aging]. / 2015 / PubMed

TCF7

• Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice. / 04.2018 / PubMed / Full text
• Age-related profiling of DNA methylation in CD8 T cells reveals changes in immune response and transcriptional regulator genes. / 19.08.2015 / PubMed / Full text

TDP1

• UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis. / 12.06.2018 / PubMed / Full text
• Neuroprotection and repair of 3'-blocking DNA ends by glaikit (gkt) encoding Drosophila tyrosyl-DNA phosphodiesterase 1 (TDP1). / 04.11.2014 / PubMed / Full text

TDRD7

• Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice. / 01.2020 / PubMed / Full text
• RNA granule component TDRD7 gene polymorphisms in a Han Chinese population with age-related cataract. / 02.2014 / PubMed / Full text

TEAD1

• [Role of PLAT, PKHD1L1, STK38L and TEAD1 genes Alu-polymorphism for longevity]. / 2016 / PubMed
• Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth. / 21.11.2016 / PubMed / Full text

TEF

• Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response. / 10.2020 / PubMed / Full text
• Relationship Between the Dose Administered, Target Tissue Dose, and Toxicity Level After Acute Oral Exposure to Bifenthrin and Tefluthrin in Young Adult Rats. / 01.12.2019 / PubMed / Full text

TEN1

• Stimulation of cell proliferation by glutathione monoethyl ester in aged bone marrow stromal cells is associated with the assistance of TERT gene expression and telomerase activity. / 08.2016 / PubMed / Full text
• Functional characterization of human CTC1 mutations reveals novel mechanisms responsible for the pathogenesis of the telomere disease Coats plus. / 12.2013 / PubMed / Full text

TERF1

• Telomere protein RAP1 levels are affected by cellular aging and oxidative stress. / 08.2016 / PubMed / Full text
• Population-specific association of genes for telomere-associated proteins with longevity in an Italian population. / 06.2015 / PubMed / Full text

TERF2

• Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text
• Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. / 11.2019 / PubMed / Full text

TES

• The Effects of Electrical Stimulation Pulse Duration on Lingual Palatal Pressure Measures During Swallowing in Healthy Older Adults. / 08.2019 / PubMed / Full text
• Comparison of different extenders on the recovery and longevity of epididymal sperm from Spix's yellow-toothed cavies (Galea spixii Wagler, 1831). / 04.2017 / PubMed / Full text

TFRC

• Identification of reference genes for RT-qPCR data normalisation in aging studies. / 27.09.2019 / PubMed / Full text
• SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence. / 06.2020 / PubMed / Full text

TGFBR2

• TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis. / 08.05.2019 / PubMed / Full text
• Serum levels of matrix metalloproteinases 2 and 9 and TGFBR2 gene screening in patients with ascending aortic dilatation. / 2013 / PubMed

TMEM119

• Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text
• Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis. / 01.07.2017 / PubMed / Full text

TMEM18

• Sequence variation in TMEM18 in association with body mass index: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text
• The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study. / 05.2013 / PubMed / Full text

TNFSF10

• Role of mitochondrial function in cell death and body metabolism. / 01.06.2016 / PubMed / Full text
• Sporadic colorectal cancer development shows rejuvenescence regarding epithelial proliferation and apoptosis. / 2013 / PubMed / Full text

TNNT1

• Improved knee extensor strength with resistance training associates with muscle specific miRNAs in older adults. / 02.2015 / PubMed / Full text
• Human slow troponin T (TNNT1) pre-mRNA alternative splicing is an indicator of skeletal muscle response to resistance exercise in older adults. / 12.2014 / PubMed / Full text

TNR

• Estimation of effectiveness of three methods of feral cat population control by use of a simulation model. / 15.08.2013 / PubMed / Full text
• The extracellular matrix glycoprotein tenascin-R affects adult but not developmental neurogenesis in the olfactory bulb. / 19.06.2013 / PubMed / Full text

TOMM20

• Effect of aging on mitochondria and metabolism of bovine granulosa cells. / 13.09.2020 / PubMed / Full text
• PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis. / 2015 / PubMed / Full text

TOP1

• UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis. / 12.06.2018 / PubMed / Full text
• mir-24 activity propagates stress-induced senescence by down regulating DNA topoisomerase 1. / 03.2016 / PubMed / Full text

TOP2A

• Proteomics of Long-Lived Mammals. / 03.2020 / PubMed / Full text
• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

TOX

• Temporal Cognitive Decline Associated With Exposure to Infectious Agents in a Population-based, Aging Cohort. / 07-09.2016 / PubMed / Full text
• Incidence rate of modifying or discontinuing first combined antiretroviral therapy regimen due to toxicity during the first year of treatment stratified by age. / 01-02.2014 / PubMed / Full text

TPX2

• Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells. / 2018 / PubMed / Full text
• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

TREX1

• Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. / 2019 / PubMed / Full text
• Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

TRIM21

• TRIM21 overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma. / 2020 / PubMed / Full text
• PRMT5-TRIM21 interaction regulates the senescence of osteosarcoma cells by targeting the TXNIP/p21 axis. / 05.02.2020 / PubMed / Full text

TRIM28

• Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau. / 04.06.2018 / PubMed / Full text
• Polyphenic trait promotes liver cancer in a model of epigenetic instability in mice. / 07.2017 / PubMed / Full text

TRIP13

• BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome. / 02.01.2020 / PubMed / Full text
• PCH-2 regulates Caenorhabditis elegans lifespan. / 01.2015 / PubMed / Full text

TRPC3

• Age-dependent alpha-synuclein accumulation is correlated with elevation of mitochondrial TRPC3 in the brains of monkeys and mice. / 04.2017 / PubMed / Full text
• TRPC3 channels critically regulate hippocampal excitability and contextual fear memory. / 15.03.2015 / PubMed / Full text

TRPC5

• TRPC5 channel modulates endothelial cells senescence. / 05.05.2017 / PubMed / Full text
• Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way. / 02.2017 / PubMed / Full text

TRPC6

• Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype. / 11.2020 / PubMed / Full text
• TRPC6 in simulated microgravity of intervertebral disc cells. / 10.2018 / PubMed / Full text

TRPM6

• Role of kinase-coupled TRP channels in mineral homeostasis. / 04.2018 / PubMed / Full text
• Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. / 19.12.2016 / PubMed / Full text

TRPM7

• mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development. / 10.2018 / PubMed / Full text
• Role of kinase-coupled TRP channels in mineral homeostasis. / 04.2018 / PubMed / Full text

TRPV6

• Changes in expression of klotho affect physiological processes, diseases, and cancer. / 01.2018 / PubMed / Full text
• Molecular aspects of intestinal calcium absorption. / 21.06.2015 / PubMed / Full text

TSHB

• Adipose TSHB in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence. / 2018 / PubMed / Full text
• Loss of basal and TRH-stimulated Tshb expression in dispersed pituitary cells. / 01.2015 / PubMed / Full text

TSLP

• Cloning and expression of recombinant equine interleukin-3 and its effect on sulfidoleukotriene and cytokine production by equine peripheral blood leukocytes. / 15.02.2015 / PubMed / Full text
• Accumulation of prelamin A compromises NF-κB-regulated B-lymphopoiesis in a progeria mouse model. / 2013 / PubMed / Full text

TTN

• LncRNA TTN-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis. / 10.10.2019 / PubMed / Full text
• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

UBB

• Different Expression Levels of Human Mutant Ubiquitin B (UBB ) Can Modify Chronological Lifespan or Stress Resistance of [i]Saccharomyces cerevisiae[/i]. / 2018 / PubMed / Full text
• Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast. / 20.03.2015 / PubMed / Full text

UGT1A1

• Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain. / 07.2015 / PubMed / Full text
• Age-related changes in mRNA levels of hepatic transporters, cytochrome P450 and UDP-glucuronosyltransferase in female rats. / 06.2015 / PubMed / Full text

ULBP2

• NKG2D ligands mediate immunosurveillance of senescent cells. / 02.2016 / PubMed / Full text
• Type 1 interferons contribute to the clearance of senescent cell. / 2015 / PubMed / Full text

UMOD

• The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. / 03.2019 / PubMed / Full text
• A roadmap for the genetic analysis of renal aging. / 10.2015 / PubMed / Full text

UNG

• UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans. / 01.05.2018 / PubMed / Full text
• Caenorhabditis elegans EXO-3 contributes to longevity and reproduction: differential roles in somatic cells and germ cells. / 02.2015 / PubMed / Full text

USP10

• The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan. / 09.2020 / PubMed / Full text
• Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c-kit( ) cardiac progenitor cells by promoting miR-675. / 08.2016 / PubMed / Full text

USP14

• Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text
• Compensatory increase in USP14 activity accompanies impaired proteasomal proteolysis during aging. / 01-02.2013 / PubMed / Full text

VASH1

• Double-Face of Vasohibin-1 for the Maintenance of Vascular Homeostasis and Healthy Longevity. / 01.06.2018 / PubMed / Full text
• Age-associated downregulation of vasohibin-1 in vascular endothelial cells. / 10.2016 / PubMed / Full text

VASP

• Reversal of Aging-Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein-Protein Interfaces. / 18.07.2018 / PubMed / Full text
• In vitro anti-platelet potency of ticagrelor in blood samples from infants and children. / 09.2015 / PubMed / Full text

VCAN

• Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis. / 07.06.2019 / PubMed / Full text
• Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells. / 2019 / PubMed / Full text

VGF

• Voluntary Running Triggers VGF-Mediated Oligodendrogenesis to Prolong the Lifespan of Snf2h-Null Ataxic Mice. / 11.10.2016 / PubMed / Full text
• Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans. / 06.10.2015 / PubMed / Full text

VGLL3

• The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon (Salmo salar L.) Males. / 11.2015 / PubMed / Full text
• Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon. / 17.12.2015 / PubMed / Full text

VGLL4

• The lncRNA MEG3/miR-16-5p/VGLL4 regulatory axis is involved in etoposide-induced senescence of tumor cells. / 03.11.2020 / PubMed / Full text
• Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth. / 21.11.2016 / PubMed / Full text

VIPR2

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
• Chromatin remodeling of human subtelomeres and TERRA promoters upon cellular senescence: commonalities and differences between chromosomes. / 05.2013 / PubMed / Full text

VPS29

• Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development. / 16.01.2019 / PubMed / Full text
• The retromer complex system in a transgenic mouse model of AD: influence of age. / 04.2017 / PubMed / Full text

VPS35

• Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development. / 16.01.2019 / PubMed / Full text
• Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis. / 11.02.2014 / PubMed / Full text

WFIKKN1

• Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults. / 01.01.2019 / PubMed / Full text
• A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes. / 08.2017 / PubMed / Full text

WFIKKN2

• Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults. / 01.01.2019 / PubMed / Full text
• A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes. / 08.2017 / PubMed / Full text

WFS1

• Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila. / 01.2018 / PubMed / Full text
• A nonsynonymous mutation in the WFS1 gene in a Finnish family with age-related hearing impairment. / 11.2017 / PubMed / Full text

WIPI2

• Neuronal autophagy declines substantially with age and is rescued by overexpression of WIPI2. / 02.2020 / PubMed / Full text
• The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. / 04.2019 / PubMed / Full text

WWP1

• The ubiquitin ligase WWP1 contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart. / 01.10.2020 / PubMed / Full text
• Overexpression of miR-584-5p inhibits proliferation and induces apoptosis by targeting WW domain-containing E3 ubiquitin protein ligase 1 in gastric cancer. / 21.04.2017 / PubMed / Full text

YY1

• Distinct Age-Related Epigenetic Signatures in CD4 and CD8 T Cells. / 2020 / PubMed / Full text
• Low mitochondrial DNA content associates with familial longevity: the Leiden Longevity Study. / 06.2014 / PubMed / Full text

ZC3H12A

• Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation. / 12.2019 / PubMed / Full text
• Prediction and characterization of human ageing-related proteins by using machine learning. / 06.03.2018 / PubMed / Full text

ZEB2

• miR-200b regulates cellular senescence and inflammatory responses by targeting ZEB2 in pulmonary emphysema. / 12.2020 / PubMed / Full text
• MicroRNA-145 induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by ZEB2. / 05.2019 / PubMed / Full text

ZFX

• ZFX knockdown inhibits growth and migration of non-small cell lung carcinoma cell line H1299. / 2013 / PubMed / Full text
• ZFX regulates glioma cell proliferation and survival in vitro and in vivo. / 03.2013 / PubMed / Full text

ZNF521

• Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells. / 21.06.2019 / PubMed / Full text
• Zinc finger factor 521 enhances adipogenic differentiation of mouse multipotent cells and human bone marrow mesenchymal stem cells. / 20.06.2015 / PubMed / Full text

ZP2

• Coenzyme Q10 ameliorates the quality of postovulatory aged oocytes by suppressing DNA damage and apoptosis. / 01.11.2019 / PubMed / Full text
• Melatonin improves the fertilization ability of post-ovulatory aged mouse oocytes by stabilizing ovastacin and Juno to promote sperm binding and fusion. / 01.03.2017 / PubMed / Full text

ZSCAN10

• RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells. / 10.10.2017 / PubMed / Full text
• ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors. / 09.2017 / PubMed / Full text

ABCC1

• Dual pathways mediate β-amyloid stimulated glutathione release from astrocytes. / 12.2015 / PubMed / Full text

ABCC3

• Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life. / 07.2016 / PubMed / Full text

ABCC8

• A mouse model of human hyperinsulinism produced by the E1506K mutation in the sulphonylurea receptor SUR1. / 11.2013 / PubMed / Full text

ABCE1

• Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain. / 27.11.2018 / PubMed / Full text

ABHD12

• Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype. / 2019 / PubMed / Full text

ABI3BP

• Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing ABI3BP in gallbladder cancer cells. / 07.06.2019 / PubMed / Full text

ABL1

• European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia. / 04.2020 / PubMed / Full text

ABLIM3

• Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization. / 05.2018 / PubMed / Full text

ABRA

• LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys. / 11.2013 / PubMed / Full text

ACAA2

• p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria. / 10.06.2016 / PubMed / Full text

ACAD9

• Identification of a novel mitochondrial complex I assembly factor ACDH-12 in Caenorhabditis elegans. / 05.2019 / PubMed / Full text

ACADM

• High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats. / 07.2018 / PubMed / Full text

ACER2

• Alkaline ceramidase family: The first two decades. / 01.12.2020 / PubMed / Full text

ACKR2

• Atypical chemokine receptor ACKR2 mediates chemokine scavenging by primary human trophoblasts and can regulate fetal growth, placental structure, and neonatal mortality in mice. / 15.11.2014 / PubMed / Full text

ACMSD

• De novo NAD synthesis enhances mitochondrial function and improves health. / 11.2018 / PubMed / Full text

ACO2

• Thioredoxin protects mitochondrial structure, function and biogenesis in myocardial ischemia-reperfusion via redox-dependent activation of AKT-CREB- PGC1α pathway in aged mice. / 13.10.2020 / PubMed / Full text

ACP2

• Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text

ACSL1

• The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats. / 09.2020 / PubMed / Full text

ACSL5

• Ageing sensitized by iPLA β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids. / 12.2017 / PubMed / Full text

ACTA2

• Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. / 2018 / PubMed / Full text

ACTL7B

• Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. / 12.2017 / PubMed / Full text

ACTR3B

• Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text

ADA2

• Manganese(II) Chloride Alters Nucleotide and Nucleoside Catabolism in Zebrafish (Danio rerio) Adult Brain. / 05.2018 / PubMed / Full text

ADAM19

• ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text

ADAM22

• Expression of NgR1-antagonizing proteins decreases with aging and cognitive decline in rat hippocampus. / 05.2013 / PubMed / Full text

ADAM9

• [The effect of PNS on the content and activity of alpha-secretase in the brains of SAMP8 mice with alzheimer's disease]. / 11.2012 / PubMed

ADAMTS1

• Increased ADAMTS1 mediates SPARC-dependent collagen deposition in the aging myocardium. / 01.06.2016 / PubMed / Full text

ADAMTS10

• Influence of Age on Ocular Biomechanical Properties in a Canine Glaucoma Model with ADAMTS10 Mutation. / 2016 / PubMed / Full text

ADAMTS3

• Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text

ADAMTS5

• Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritis chondrocytes. / 16.09.2017 / PubMed / Full text

ADAMTS7

• Identification of cardiovascular health gene variants related to longevity in a Chinese population. / 07.09.2020 / PubMed / Full text

ADAR

• Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. / 09.2018 / PubMed / Full text

ADCK1

• Functional analysis of Aarf domain-containing kinase 1 in Drosophila melanogaster. / 09.2019 / PubMed / Full text

ADD2

• SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

ADK

• Deletion of pancreatic β-cell adenosine kinase improves glucose homeostasis in young mice and ameliorates streptozotocin-induced hyperglycaemia. / 07.2019 / PubMed / Full text

ADNP2

• ADNP differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. / 06.2019 / PubMed / Full text

ADORA2B

• Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss. / 12.2020 / PubMed / Full text

ADRA2A

• α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway. / 2020 / PubMed / Full text

ADRM1

• Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. / 01.08.2018 / PubMed / Full text

AGAP2

• Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2. / 05.08.2019 / PubMed / Full text

AGO1

• A transcriptome-wide study on the microRNA- and the Argonaute 1-enriched small RNA-mediated regulatory networks involved in plant leaf senescence. / 03.2016 / PubMed / Full text

AGRP

• Influence of Aging and Gender Differences on Feeding Behavior and Ghrelin-Related Factors during Social Isolation in Mice. / 2015 / PubMed / Full text

AHNAK

• A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging. / 2015 / PubMed / Full text

AHSP

• Relationship between Sensory Perception and Frailty in a Community-Dwelling Elderly Population. / 2017 / PubMed / Full text

AIF1

• Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text

AK1

• Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text

AKAP11

• Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II). / 2016 / PubMed / Full text

AKAP12

• A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter. / 05.2018 / PubMed / Full text

AKAP17A

• The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. / 10.2019 / PubMed / Full text

AKIP1

• Expression of potato RNA-binding proteins StUBA2a/b and StUBA2c induces hypersensitive-like cell death and early leaf senescence in Arabidopsis. / 07.2015 / PubMed / Full text

AKR1B1

• Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells. / 01.04.2016 / PubMed / Full text

AKR1C2

• Identification of a gene signature of a pre-transformation process by senescence evasion in normal human epidermal keratinocytes. / 14.06.2014 / PubMed / Full text

AKR1C3

• Identification of a gene signature of a pre-transformation process by senescence evasion in normal human epidermal keratinocytes. / 14.06.2014 / PubMed / Full text

AKR7A3

• The aged testis. A good model to find proteins involved in age-related changes of testis by proteomic analysis. / 01-02.2014 / PubMed

ALAD

• Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. / 2016 / PubMed / Full text

ALAS1

• Heterozygous disruption of ALAS1 in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver. / 08.12.2020 / PubMed / Full text

ALAS2

• Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. / 01.2016 / PubMed / Full text

ALCAM

• Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging. / 10.2020 / PubMed / Full text

ALDH1L1

• Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role. / 06.2017 / PubMed / Full text

ALDH3A1

• Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs). / 13.02.2019 / PubMed / Full text

ALDH4A1

• An integrated metabolomic and gene expression analysis identifies heat and calcium metabolic networks underlying postharvest sweet cherry fruit senescence. / 12.2019 / PubMed / Full text

ALKBH1

• ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed

ALKBH2

• ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed

ALOX12

• Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer. / 15.05.2020 / PubMed / Full text

ALOX15B

• Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism. / 04.2020 / PubMed / Full text

ALPL

• Physiological blood-brain transport is impaired with age by a shift in transcytosis. / 07.2020 / PubMed / Full text

ALS2

• Age-dependent deterioration of locomotion in Drosophila melanogaster deficient in the homologue of amyotrophic lateral sclerosis 2. / 06.2014 / PubMed / Full text

ALX4

• Age-associated genes in human mammary gland drive human breast cancer progression. / 15.06.2020 / PubMed / Full text

AMBRA1

• MiR-23a-depressed autophagy is a participant in PUVA- and UVB-induced premature senescence. / 21.06.2016 / PubMed / Full text

AMFR

• Mice heterozygous for the Cdh23/Ahl1 mutation show age-related deficits in auditory temporal processing. / 09.2019 / PubMed / Full text

ANGPT1

• Altered microRNA expression in bovine skeletal muscle with age. / 06.2015 / PubMed / Full text

ANGPT2

• Systemic analysis of gene expression profiles in porcine granulosa cells during aging. / 14.11.2017 / PubMed / Full text

ANGPTL4

• Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. / 05.2019 / PubMed / Full text

ANGPTL8

• Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice. / 07.2015 / PubMed / Full text

ANK2

• SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

ANKS1B

• Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text

ANPEP

• Aminopeptidase N expression in the endometrium could affect endometrial receptivity. / 25.06.2019 / PubMed / Full text

ANXA1

• Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging. / 26.10.2018 / PubMed / Full text

ANXA2

• Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers. / 08.10.2013 / PubMed / Full text

AOC1

• Identification and functional characterization of a rice NAC gene involved in the regulation of leaf senescence. / 12.09.2013 / PubMed / Full text

AOX1

• N1-Methylnicotinamide: An Anti-Ovarian Aging Hormetin? / 09.2020 / PubMed / Full text

APAF1

• Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. / 10.2016 / PubMed / Full text

APBB2

• GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension. / 10.2015 / PubMed / Full text

APLN

• Relationship of age and body mass index to the expression of obesity and osteoarthritis-related genes in human meniscus. / 09.2013 / PubMed / Full text

APLNR

• Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects. / 13.09.2017 / PubMed / Full text

APOA4

• No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes. / 06.2016 / PubMed / Full text

APOBEC1

• Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology. / 12.12.2017 / PubMed / Full text

APOC1

• Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text

APOC2

• Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia. / 01.08.2015 / PubMed / Full text

APOH

• Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults. / 31.03.2016 / PubMed / Full text

APPL1

• Insulin and adipokine signaling and their cross-regulation in postmortem human brain. / 12.2019 / PubMed / Full text

AQP9

• Seasonal and Ageing-Depending Changes of Aquaporins 1 and 9 Expression in the Genital Tract of Buffalo Bulls (Bubalus bubalis). / 08.2016 / PubMed / Full text

AQR

• Synergism between soluble guanylate cyclase signaling and neuropeptides extends lifespan in the nematode Caenorhabditis elegans. / 04.2017 / PubMed / Full text

ARG1

• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

ARG2

• Arginase-2, a miR-1299 target, enhances pigmentation in melasma by reducing melanosome degradation via senescence-induced autophagy inhibition. / 01.2017 / PubMed / Full text

ARHGAP1

• Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. / 01.12.2016 / PubMed / Full text

ARID5A

• Differentially regulated gene expression in quiescence versus senescence and identification of ARID5A as a quiescence associated marker. / 05.2018 / PubMed / Full text

ARID5B

• Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism. / 04.2020 / PubMed / Full text

ARIH2

• A novel feed-forward loop between ARIH2 E3-ligase and PABPN1 regulates aging-associated muscle degeneration. / 04.2014 / PubMed / Full text

ARL13B

• ARL13B, a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments. / 20.02.2019 / PubMed / Full text

ARL4C

• LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys. / 11.2013 / PubMed / Full text

ARNTL2

• Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text

ARRB2

• Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity. / 12.2019 / PubMed / Full text

ARSA

• Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

ASB3

• Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype. / 02.2019 / PubMed / Full text

ASB7

• ASB7 Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation. / 2020 / PubMed / Full text

ASF1A

• Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging. / 04.2014 / PubMed / Full text

ASIC2

• Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration. / 04.2013 / PubMed / Full text

ASIP

• Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation. / 10.2018 / PubMed / Full text

ASMT

• The influence of ageing on the extrapineal melatonin synthetic pathway. / 09.2018 / PubMed / Full text

ASPN

• The association between higher social support and lower depressive symptoms among aging services clients is attenuated at higher levels of functional impairment. / 10.2015 / PubMed / Full text

ATG10

• Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

ATG13

• Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autophagy, in the liver of middle-aged mice. / 10.2016 / PubMed / Full text

ATG16L1

• The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. / 04.2019 / PubMed / Full text

ATG16L2

• Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats. / 06.2017 / PubMed / Full text

ATG4B

• Impaired autophagic activity and ATG4B deficiency are associated with increased endoplasmic reticulum stress-induced lung injury. / 27.08.2018 / PubMed / Full text

ATG4D

• Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats. / 17.07.2019 / PubMed / Full text

ATMIN

• Perturbed hematopoiesis in mice lacking ATMIN. / 20.10.2016 / PubMed / Full text

ATP13A2

• Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits. / 15.05.2013 / PubMed / Full text

ATP1A3

• The Influence of Na( ), K( )-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence. / 2016 / PubMed / Full text

ATP2B1

• Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries. / 10.2017 / PubMed / Full text

ATP6V0C

• A pH probe inhibits senescence in mesenchymal stem cells. / 07.12.2018 / PubMed / Full text

ATP6V1G1

• Chemical screening identifies ATM as a target for alleviating senescence. / 06.2017 / PubMed / Full text

ATP7B

• [Copper intoxication decreases lifespan and induces neurologic alterations in Drosophila melanogaster]. / 03.2013 / PubMed

ATXN1

• Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text

AURKB

• Aurora kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction. / 06.2020 / PubMed / Full text

AURKC

• Aurora kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction. / 06.2020 / PubMed / Full text

AVPR1A

• Introduction of the human AVPR1A gene substantially alters brain receptor expression patterns and enhances aspects of social behavior in transgenic mice. / 08.2014 / PubMed / Full text

BAALC

• Relation of BAALC and ERG Gene Expression with Overall Survival in Acute Myeloid Leukemia Cases. / 2015 / PubMed / Full text

BAAT

• Prevalence and associated metabolic factors of fatty liver disease in the elderly. / 08.2013 / PubMed / Full text

BACE2

• Lessons from a BACE1 inhibitor trial: off-site but not off base. / 10.2014 / PubMed / Full text

BAG2

• BAG2 Interferes with CHIP-Mediated Ubiquitination of HSP72. / 30.12.2016 / PubMed / Full text

BAG5

• miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1. / 12.03.2020 / PubMed / Full text

BAP1

• The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. / 27.11.2015 / PubMed / Full text

BAZ1A

• Chromatin remodeling factor BAZ1A regulates cellular senescence in both cancer and normal cells. / 15.07.2019 / PubMed / Full text

BAZ2B

• Two conserved epigenetic regulators prevent healthy ageing. / 03.2020 / PubMed / Full text

BBC3

• The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators. / 29.09.2020 / PubMed / Full text

BBS5

• Progressive Characterization of Visual Phenotype in Bardet-Biedl Syndrome Mutant Mice. / 01.03.2019 / PubMed / Full text

BCAS1

• Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs). / 13.02.2019 / PubMed / Full text

BCL2L11

• miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence. / 01.2020 / PubMed / Full text

BCORL1

• Age-related mutations associated with clonal hematopoietic expansion and malignancies. / 12.2014 / PubMed / Full text

BFSP1

• The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling. / 04.2017 / PubMed / Full text

BHLHE40

• Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1. / 07.2020 / PubMed / Full text

BICD1

• Kidney Allograft Telomere Length Is Not Associated with Sex, Recipient Comorbid Conditions, Post-Transplant Infections, or CMV Reactivation. / 28.06.2016 / PubMed / Full text

BIRC5

• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

BLVRA

• Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration. / 09.2020 / PubMed / Full text

BMP5

• BMP5 expression in the adult rat brain. / 22.01.2015 / PubMed / Full text

BNC1

• Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. / 22.01.2020 / PubMed / Full text

BNC2

• Genetic variants associated with skin aging in the Chinese Han population. / 04.2017 / PubMed / Full text

BOC

• Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations. / 01.05.2020 / PubMed / Full text

BOK

• Comparative proteomic analysis of primordial follicles from ovaries of immature and aged rats. / 2015 / PubMed / Full text

BRD3

• Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. / 07.2019 / PubMed / Full text

BRD7

• XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence. / 02.02.2016 / PubMed / Full text

BRINP1

• Absence of BRINP1 in mice causes increase of hippocampal neurogenesis and behavioral alterations relevant to human psychiatric disorders. / 14.02.2014 / PubMed / Full text

BSG

• Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients. / 03.09.2019 / PubMed / Full text

BTG3

• Investigating the specific core genetic-and-epigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells. / 23.02.2016 / PubMed / Full text

BTG4

• Age-related decrease of IF5/BTG4 in oral and respiratory cavities in mice. / 2015 / PubMed / Full text

BUB1

• Links between nucleolar activity, rDNA stability, aneuploidy and chronological aging in the yeast Saccharomyces cerevisiae. / 06.2014 / PubMed / Full text

C1QA

• APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction. / 10.2015 / PubMed / Full text

C2CD2

• Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort. / 20.11.2017 / PubMed / Full text

C4A

• Investigation of complement component C4 copy number variation in human longevity. / 2014 / PubMed / Full text

C4B

• Investigation of complement component C4 copy number variation in human longevity. / 2014 / PubMed / Full text

C8orf48

• Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model. / 07.2014 / PubMed / Full text

CA10

• Genome wide association study of age at menarche in the Japanese population. / 2013 / PubMed / Full text

CABLES1

• CABLES1 Deficiency Impairs Quiescence and Stress Responses of Hematopoietic Stem Cells in Intrinsic and Extrinsic Manners. / 13.08.2019 / PubMed / Full text

CACNA1B

• Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

CACNA1F

• Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics. / 08.06.2016 / PubMed / Full text

CACNA1S

• Increased calcium channel in the lamina propria of aging rat. / 31.10.2019 / PubMed / Full text

CACNA2D1

• Pregabalin can prevent, but not treat, cognitive dysfunction following abdominal surgery in aged rats. / 01.03.2016 / PubMed / Full text

CADM2

• GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. / 01.2015 / PubMed / Full text

CALHM1

• CALHM1 Deletion in Mice Affects Glossopharyngeal Taste Responses, Food Intake, Body Weight, and Life Span. / 07.2015 / PubMed / Full text

CAMK2A

• Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer's disease animal model. / 2013 / PubMed / Full text

CAMKK2

• The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan. / 09.2020 / PubMed / Full text

CAMP

• [Study on effect of astragali radix polysaccharides in improving learning and memory functions in aged rats and its mechanism]. / 06.2014 / PubMed

CAMSAP1

• Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text

CAP1

• Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text

CAP2

• Targeting MRTF/SRF in CAP2-dependent dilated cardiomyopathy delays disease onset. / 21.03.2019 / PubMed / Full text

CAPN1

• Defects in the CAPN1 Gene Result in Alterations in Cerebellar Development and Cerebellar Ataxia in Mice and Humans. / 28.06.2016 / PubMed / Full text

CAPRIN1

• Reduced Levels of the Synaptic Functional Regulator FMRP in Dentate Gyrus of the Aging Sprague-Dawley Rat. / 2017 / PubMed / Full text

CARD14

• Elderly-Onset Generalized Pustular Psoriasis without a Previous History of Psoriasis Vulgaris. / 05-08.2015 / PubMed / Full text

CARMIL1

• Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text

CASP2

• Dual role of the caspase enzymes in satellite cells from aged and young subjects. / 12.12.2013 / PubMed / Full text

CASP5

• Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age. / 2015 / PubMed / Full text

CASP6

• Dual role of the caspase enzymes in satellite cells from aged and young subjects. / 12.12.2013 / PubMed / Full text

CASP9

• Dual role of the caspase enzymes in satellite cells from aged and young subjects. / 12.12.2013 / PubMed / Full text

CBR1

• Age-related changes in hepatic activity and expression of detoxification enzymes in male rats. / 2013 / PubMed / Full text

CBSL

• Effect of a Community-Based Service Learning Experience in Geriatrics on Internal Medicine Residents and Community Participants. / 09.2017 / PubMed / Full text

CBX1

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text

CBX2

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text

CBX3

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text

CBX5

• The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence. / 03.03.2017 / PubMed / Full text

CBX6

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text

CCAR2

• CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans. / 10.2018 / PubMed / Full text

CCDC102B

• Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system. / 09.2016 / PubMed / Full text

CCDC17

• Aberrant DNA Methylation in Keratoacanthoma. / 2016 / PubMed / Full text

CCDC71L

• Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text

CCDC85A

• Genome wide association study of age at menarche in the Japanese population. / 2013 / PubMed / Full text

CCDC88A

• Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

CCL18

• Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text

CCL23

• Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy. / 2019 / PubMed / Full text

CCL25

• Age-related chemokine alterations affect IgA secretion and gut immunity in female mice. / 10.2020 / PubMed / Full text

CCL26

• Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state. / 11.2014 / PubMed / Full text

CCL28

• Age-related chemokine alterations affect IgA secretion and gut immunity in female mice. / 10.2020 / PubMed / Full text

CCL8

• Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists. / 15.08.2017 / PubMed / Full text

CCM2

• Vascular permeability in cerebral cavernous malformations. / 10.2015 / PubMed / Full text

CCN4

• CCN proteins as potential actionable targets in scleroderma. / 01.2019 / PubMed / Full text

CCNA1

• Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. / 02.10.2017 / PubMed / Full text

CCNB2

• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

CCND2

• Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma. / 10.2018 / PubMed / Full text

CCND3

• The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text

CCNE1

• Hepatoprotective effects of hydroxysafflor yellow A in D-galactose-treated aging mice. / 15.08.2020 / PubMed / Full text

CCNE2

• Circular RNA CircCCNB1 sponges micro RNA-449a to inhibit cellular senescence by targeting CCNE2. / 25.11.2019 / PubMed / Full text

CCNI

• Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. / 15.08.2013 / PubMed / Full text

CCNI2

• Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. / 15.08.2013 / PubMed / Full text

CCR1

• Myocardial Infarction Superimposed on Aging: MMP-9 Deletion Promotes M2 Macrophage Polarization. / 04.2016 / PubMed / Full text

CCR10

• Cardiac aging is initiated by matrix metalloproteinase-9-mediated endothelial dysfunction. / 15.05.2014 / PubMed / Full text

CCR9

• Attenuation of migration properties of CD4 T cells from aged mice correlates with decrease in chemokine receptor expression, response to retinoic acid, and RALDH expression compared to young mice. / 2014 / PubMed / Full text

CCT8

• Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan. / 28.11.2016 / PubMed / Full text

CD207

• Neurogenic factor-induced Langerhans cell activation in diabetic mice with mechanical allodynia. / 14.05.2013 / PubMed / Full text

CD226

• T-cell Immunoglobulin and ITIM Domain Contributes to CD8 T-cell Immunosenescence. / 04.2018 / PubMed / Full text

CD244

• Association of Epigenetic Age and p16INK4a With Markers of T-Cell Composition in a Healthy Cohort. / 13.11.2020 / PubMed / Full text

CD3G

• Phenotypic characteristics of aged CD4 CD28 T lymphocytes are determined by changes in the whole-genome DNA methylation pattern. / 04.2017 / PubMed / Full text

CD48

• Genetic overexpression of COMP-Ang1 impairs BM microenvironment and induces senescence of BM HSCs. / 15.05.2018 / PubMed / Full text

CD55

• Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia. / 15.11.2018 / PubMed / Full text

CD59

• Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria. / 2019 / PubMed / Full text

CD6

• Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures. / 05.2016 / PubMed / Full text

CD72

• Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation. / 2019 / PubMed / Full text

CD82

• Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis. / 01.11.2018 / PubMed / Full text

CD83

• Human mesothelioma induces defects in dendritic cell numbers and antigen-processing function which predict survival outcomes. / 02.2016 / PubMed / Full text

CD8A

• Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy. / 2019 / PubMed / Full text

CD8B

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

CDC20

• Premature aging syndrome showing random chromosome number instabilities with CDC20 mutation. / 11.2020 / PubMed / Full text

CDC5L

• Comparative transcriptome analysis of Parkinson's disease and Hutchinson-Gilford progeria syndrome reveals shared susceptible cellular network processes. / 18.08.2020 / PubMed / Full text

CDC6

• A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence. / 10.01.2018 / PubMed / Full text

CDC7

• CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR-7 activity via sponge decoy vectors. / 03.2014 / PubMed / Full text

CDC73

• Down-regulation of cancer-associated gene CDC73 contributes to cellular senescence. / 23.05.2018 / PubMed / Full text

CDCA3

• Expression of CDCA3 Is a Prognostic Biomarker and Potential Therapeutic Target in Non-Small Cell Lung Cancer. / 07.2017 / PubMed / Full text

CDCA4

• A multidimensional systems biology analysis of cellular senescence in aging and disease. / 07.04.2020 / PubMed / Full text

CDH2

• CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type. / 30.11.2018 / PubMed / Full text

CDH23

• Compound heterozygosity of the functionally null Cdh23(v-ngt) and hypomorphic Cdh23(ahl) alleles leads to early-onset progressive hearing loss in mice. / 2013 / PubMed / Full text

CDK16

• Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. / 15.08.2013 / PubMed / Full text

CDK18

• Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. / 15.08.2013 / PubMed / Full text

CDK3

• Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. / 15.08.2013 / PubMed / Full text

CDK8

• Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. / 15.08.2013 / PubMed / Full text

CDK9

• Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. / 15.08.2013 / PubMed / Full text

CDKN2C

• Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes. / 15.01.2020 / PubMed / Full text

CDO1

• The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway. / 19.09.2018 / PubMed / Full text

CDR2

• Neuro-degeneration profile of Alzheimer's patients: A brain morphometry study. / 2017 / PubMed / Full text

CEACAM1

• Aging-related carcinoembryonic antigen-related cell adhesion molecule 1 signaling promotes vascular dysfunction. / 12.2019 / PubMed / Full text

CEBPA

• Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity. / 02.08.2020 / PubMed / Full text

CEBPD

• Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

CEBPE

• Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants. / 09.2020 / PubMed / Full text

CELSR2

• Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. / 10.2016 / PubMed / Full text

CEP55

• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

CEP57

• BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome. / 02.01.2020 / PubMed / Full text

CEP95

• Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text

CERK

• MicroRNA-34a causes ceramide accumulation and effects insulin signaling pathway by targeting ceramide kinase (CERK) in aging skeletal muscle. / 06.2020 / PubMed / Full text

CFL2

• Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text

CFLAR

• Senescence-secreted factors activate Myc and sensitize pretransformed cells to TRAIL-induced apoptosis. / 06.2014 / PubMed / Full text

CH25H

• Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculature. / 21.03.2014 / PubMed / Full text

CHMP1B

• Overexpression of CHMP7 from rapeseed and Arabidopsis causes dwarfism and premature senescence in Arabidopsis. / 01.10.2016 / PubMed / Full text

CHMP2B

• Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. / 24.02.2016 / PubMed / Full text

CHMP4C

• Silencing of human papillomavirus (HPV) E6/E7 oncogene expression affects both the contents and the amounts of extracellular microvesicles released from HPV-positive cancer cells. / 01.10.2013 / PubMed / Full text

CHMP7

• Overexpression of CHMP7 from rapeseed and Arabidopsis causes dwarfism and premature senescence in Arabidopsis. / 01.10.2016 / PubMed / Full text

CHRDL1

• Identification of Human Juvenile Chondrocyte-Specific Factors that Stimulate Stem Cell Growth. / 04.2016 / PubMed / Full text

CHRFAM7A

• Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders. / 03.10.2019 / PubMed / Full text

CHRM2

• Aging-related changes in the gene expression profile of human lungs. / 09.11.2020 / PubMed / Full text

CHRM4

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

CHRNA7

• Associations between genetic variations and global motion perception. / 10.2019 / PubMed / Full text

CHRNE

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

CHSY1

• Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in [i]skt[/i] Mice. / 01.2020 / PubMed / Full text

CIC

• Cell-in-cell structures are more potent predictors of outcome than senescence or apoptosis in head and neck squamous cell carcinomas. / 18.01.2017 / PubMed / Full text

CILP

• Fibrotic-like changes in degenerate human intervertebral discs revealed by quantitative proteomic analysis. / 03.2016 / PubMed / Full text

CILP2

• Fibrotic-like changes in degenerate human intervertebral discs revealed by quantitative proteomic analysis. / 03.2016 / PubMed / Full text

CINP

• Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging. / 01-03.2019 / PubMed / Full text

CITED2

• Downregulation of CITED2 contributes to TGFβ-mediated senescence of tendon-derived stem cells. / 04.2017 / PubMed / Full text

CIZ1

• DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice. / 02.2018 / PubMed / Full text

CKAP2

• A multidimensional systems biology analysis of cellular senescence in aging and disease. / 07.04.2020 / PubMed / Full text

CLCN6

• DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy. / 02.2016 / PubMed / Full text

CLEC4E

• Comparative analysis of microbial sensing molecules in mucosal tissues with aging. / 03.2018 / PubMed / Full text

CLPTM1

• Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer. / 01.2020 / PubMed / Full text

CMA1

• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

CMKLR1

• Chemerin facilitates intervertebral disc degeneration via TLR4 and CMKLR1 and activation of NF-kB signaling pathway. / 11.06.2020 / PubMed / Full text

CNGA3

• DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers. / 07.2017 / PubMed / Full text

CNKSR3

• Differentially methylated gene patterns between age-matched sarcopenic and non-sarcopenic women. / 12.2019 / PubMed / Full text

CNOT6

• miR-29c-3p promotes senescence of human mesenchymal stem cells by targeting CNOT6 through p53-p21 and p16-pRB pathways. / 04.2016 / PubMed / Full text

CNTNAP4

• A common copy number variation (CNV) polymorphism in the CNTNAP4 gene: association with aging in females. / 2013 / PubMed / Full text

CNTRL

• Antioxidant status, lipid and color stability of aged beef from grazing steers supplemented with corn grain and increasing levels of flaxseed. / 01.2016 / PubMed / Full text

COG1

• PRX2 and PRX25, peroxidases regulated by COG1, are involved in seed longevity in Arabidopsis. / 02.2020 / PubMed / Full text

COL12A1

• Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

COL13A1

• [Alu insertion-deletion polymorphism of COL13A1 and LAMA2 genes: The analysis of association with longevity]. / 10.2016 / PubMed

COL15A1

• Smooth muscle cell-specific deletion of [i]Col15a1[/i] unexpectedly leads to impaired development of advanced atherosclerotic lesions. / 01.05.2017 / PubMed / Full text

COL17A1

• Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis. / 05.02.2016 / PubMed / Full text

COL4A3

• Frequency of COL4A3/COL4A4 mutations amongst families segregating glomerular microscopic hematuria and evidence for activation of the unfolded protein response. Focal and segmental glomerulosclerosis is a frequent development during ageing. / 2014 / PubMed / Full text

COL7A1

• Biological Effects Induced by Specific Advanced Glycation End Products in the Reconstructed Skin Model of Aging. / 2015 / PubMed / Full text

COL9A1

• Enhanced tissue regeneration potential of juvenile articular cartilage. / 11.2013 / PubMed / Full text

COQ5

• Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text

COQ6

• Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text

COQ9

• Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text

COX5A

• COX5A Plays a Vital Role in Memory Impairment Associated With Brain Aging [i]via[/i] the BDNF/ERK1/2 Signaling Pathway. / 2020 / PubMed / Full text

COX7A2

• Proteomics Analysis to Identify and Characterize the Biomarkers and Physical Activities of Non-Frail and Frail Older Adults. / 2017 / PubMed / Full text

CPA3

• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

CPB2

• Characterization of Clostridium perfringens in the feces of adult horses and foals with acute enterocolitis. / 01.2014 / PubMed / Full text

CPSF1

• Genome-wide association study for lactation persistency, female fertility, longevity, and lifetime profit index traits in Holstein dairy cattle. / 02.2017 / PubMed / Full text

CPT1A

• Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells. / 03.01.2020 / PubMed / Full text

CR2

• Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text

CRB1

• MPP3 regulates levels of PALS1 and adhesion between photoreceptors and Müller cells. / 10.2013 / PubMed / Full text

CRBN

• Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity. / 24.04.2020 / PubMed / Full text

CREB1

• Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons. / 29.08.2018 / PubMed / Full text

CREBL2

• Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence. / 2015 / PubMed / Full text

CREG1

• CREG1 ameliorates myocardial fibrosis associated with autophagy activation and Rab7 expression. / 02.2015 / PubMed / Full text

CRIP2

• Transcriptomics of cortical gray matter thickness decline during normal aging. / 15.11.2013 / PubMed / Full text

CRISPLD2

• A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text

CRK

• Crack-cocaine dependence and aging: effects on working memory. / 03.2016 / PubMed / Full text

CRTC1

• TRPV1 pain receptors regulate longevity and metabolism by neuropeptide signaling. / 22.05.2014 / PubMed / Full text

CRTC3

• A nutrigenomics approach for the study of anti-aging interventions: olive oil phenols and the modulation of gene and microRNA expression profiles in mouse brain. / 03.2017 / PubMed / Full text

CRX

• Transcription coactivators p300 and CBP are necessary for photoreceptor-specific chromatin organization and gene expression. / 2013 / PubMed / Full text

CRYAA

• Polymorphism rs7278468 is associated with Age-related cataract through decreasing transcriptional activity of the CRYAA promoter. / 17.03.2016 / PubMed / Full text

CRYL1

• Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old. / 28.03.2017 / PubMed / Full text

CSAD

• The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway. / 19.09.2018 / PubMed / Full text

CSF1

• Pleiotropic effects of extended blockade of CSF1R signaling in adult mice. / 08.2014 / PubMed / Full text

CSF3R

• Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text

CSGALNACT1

• Alterations in the chondroitin sulfate chain in human osteoarthritic cartilage of the knee. / 02.2014 / PubMed / Full text

CSN2

• Autophagic homeostasis is required for the pluripotency of cancer stem cells. / 02.2017 / PubMed / Full text

CSNK1D

• DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing. / 05.2017 / PubMed / Full text

CSNK1G2

• Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. / 18.11.2020 / PubMed / Full text

CST3

• Improved lipids, diastolic pressure and kidney function are potential contributors to familial longevity: a study on 60 Chinese centenarian families. / 25.02.2016 / PubMed / Full text

CST5

• Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy. / 2019 / PubMed / Full text

CSTF2T

• Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text

CTNS

• Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading. / 05.2020 / PubMed / Full text

CTSA

• A CTSA-based consultation service to advance research on special and underserved populations. / 16.01.2020 / PubMed / Full text

CTSC

• Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. / 24.02.2016 / PubMed / Full text

CTSK

• Transcriptome Analysis of B Cell Immune Functions in Periodontitis: Mucosal Tissue Responses to the Oral Microbiome in Aging. / 2016 / PubMed / Full text

CTSS

• SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

CTU2

• Chromosomal alterations among age-related haematopoietic clones in Japan. / 08.2020 / PubMed / Full text

CTXND1

• Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. / 03.2020 / PubMed / Full text

CUBN

• A roadmap for the genetic analysis of renal aging. / 10.2015 / PubMed / Full text

CUL3

• KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text

CUL4B

• CUL4B impedes stress-induced cellular senescence by dampening a p53-reactive oxygen species positive feedback loop. / 02.2015 / PubMed / Full text

CUX1

• Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text

CXCL14

• Identification of genes associated with endometrial cell aging. / 01.12.2020 / PubMed / Full text

CXCL17

• [Age-related aspects of the involvement of heat shock proteins in the pathogenesis of osteoarthritis]. / 2017 / PubMed

CXCR6

• CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4 T-Cell-Dependent Control of Senescence. / 05.2019 / PubMed / Full text

CXXC1

• The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators. / 29.09.2020 / PubMed / Full text

CXXC5

• Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny. / 13.10.2015 / PubMed / Full text

CYB5R3

• Overexpression of CYB5R3 and NQO1, two NAD -producing enzymes, mimics aspects of caloric restriction. / 08.2018 / PubMed / Full text

CYBA

• [Association between 242C > T polymorphism of NADPH oxidase p22phox gene (CYBA) and longevity in Russian population]. / 03.2013 / PubMed / Full text

CYCS

• The Impact of Age and Sex in DLBCL: Systems Biology Analyses Identify Distinct Molecular Changes and Signaling Networks. / 2015 / PubMed / Full text

CYP11B1

• Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼. / 11.2020 / PubMed / Full text

CYP26A1

• Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text

CYP26B1

• Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia. / 20.05.2020 / PubMed / Full text

CYP2B6

• Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation. / 07.2016 / PubMed / Full text

CYP2U1

• Genetic variants associated with lung function: the long life family study. / 01.11.2014 / PubMed / Full text

CYP4X1

• Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes. / 02.2017 / PubMed / Full text

CYP8B1

• Synergic hypocholesterolaemic effect of n-3 PUFA and oestrogen by modulation of hepatic cholesterol metabolism in female rats. / 14.12.2015 / PubMed / Full text

CYSLTR2

• Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. / 03.2020 / PubMed / Full text

DAPK2

• SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

DCAF17

• Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. / 15.06.2018 / PubMed / Full text

DCAF7

• Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text

DCHS1

• The atypical cadherin Dachsous1 localizes to the base of the ciliary apparatus in airway epithelia. / 13.05.2016 / PubMed / Full text

DCLRE1C

• Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population. / 06.2019 / PubMed / Full text

DCTN1

• Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis. / 2016 / PubMed / Full text

DCTN2

• Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text

DCTN6

• Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text

DCXR

• Dicarbonyl/l-xylulose reductase (DCXR): The multifunctional pentosuria enzyme. / 11.2013 / PubMed / Full text

DDI2

• Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. / 01.08.2018 / PubMed / Full text

DDIT3

• Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text

DDR1

• Age-related modifications of type I collagen impair DDR1-induced apoptosis in non-invasive breast carcinoma cells. / 2018 / PubMed / Full text

DDX25

• Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice. / 01.2020 / PubMed / Full text

DEFB1

• Association of Polymorphisms in Innate Immunity Genes TLR9 and DEFB1 with Human Longevity. / 05.2015 / PubMed / Full text

DEFB4B

• Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. / 21.12.2019 / PubMed / Full text

DEK

• Altered miRNA and mRNA Expression in Sika Deer Skeletal Muscle with Age. / 06.02.2020 / PubMed / Full text

DEPDC1

• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

DEPDC5

• KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text

DEPTOR

• DEPTOR at the Nexus of Cancer, Metabolism, and Immunity. / 01.07.2018 / PubMed / Full text

DGAT2

• Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text

DHCR7

• Environmental and genetic determinants of vitamin D status among older adults in London, UK. / 11.2016 / PubMed / Full text

DHRS2

• Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts. / 08.05.2018 / PubMed / Full text

DHX57

• Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum. / 02.02.2016 / PubMed / Full text

DIP2A

• Blocking the FSTL1-DIP2A Axis Improves Anti-tumor Immunity. / 14.08.2018 / PubMed / Full text

DKK3

• Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging. / 07.2014 / PubMed / Full text

DLAT

• Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

DLG1

• Altered expression of genes for Kir ion channels in dilated cardiomyopathy. / 08.2013 / PubMed / Full text

DLGAP2

• Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. / 01.09.2020 / PubMed / Full text

DLK1

• Dual role of delta-like 1 homolog (DLK1) in skeletal muscle development and adult muscle regeneration. / 09.2013 / PubMed / Full text

DLL1

• MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting DLL1 and Regulating PI3K/AKT Pathway. / 2018 / PubMed / Full text

DLL4

• Dynamic regulation of NOTCH1 activation and Notch ligand expression in human thymus development. / 13.08.2018 / PubMed / Full text

DLX2

• A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM-p53 signaling. / 01.02.2016 / PubMed / Full text

DMPK

• Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans. / 19.04.2019 / PubMed / Full text

DMRT1

• The Jak-STAT target Chinmo prevents sex transformation of adult stem cells in the Drosophila testis niche. / 24.11.2014 / PubMed / Full text

DNAJB9

• DNAJB9 Inhibits p53-Dependent Oncogene-Induced Senescence and Induces Cell Transformation. / 30.04.2020 / PubMed / Full text

DNAJC2

• ZRF1 is a novel S6 kinase substrate that drives the senescence programme. / 15.03.2017 / PubMed / Full text

DNM1

• Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice. / 2018 / PubMed / Full text

DNM1L

• Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2 mice. / 10.12.2020 / PubMed / Full text

DNM2

• Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy. / 19.11.2018 / PubMed / Full text

DNMT3L

• Transient DNMT3L Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast. / 2020 / PubMed / Full text

DOCK7

• Altered thermogenesis and impaired bone remodeling in Misty mice. / 09.2013 / PubMed / Full text

DPP6

• A novel structure associated with aging is augmented in the DPP6-KO mouse brain. / 23.11.2020 / PubMed / Full text

DPYSL2

• Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text

DRAM2

• SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

DSC1

• HDLs and the pathogenesis of atherosclerosis. / 05.2018 / PubMed / Full text

DSC2

• Age-dependent clinical and genetic characteristics in Japanese patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia. / 2013 / PubMed / Full text

DSG1

• Genetic effects on information processing speed are moderated by age--converging results from three samples. / 06.2014 / PubMed / Full text

DTL

• Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells. / 2018 / PubMed / Full text

DTNBP1

• Genetic Biomarkers on Age-Related Cognitive Decline. / 2017 / PubMed / Full text

DTX1

• Analysis of diarrhetic shellfish poisoning toxins and pectenotoxin-2 in the bottlenose dolphin (Tursiops truncatus) by liquid chromatography-tandem mass spectrometry. / 16.10.2015 / PubMed / Full text

DTX2

• Analysis of diarrhetic shellfish poisoning toxins and pectenotoxin-2 in the bottlenose dolphin (Tursiops truncatus) by liquid chromatography-tandem mass spectrometry. / 16.10.2015 / PubMed / Full text

DUOX1

• Lifespan extension by peroxidase and dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in [i]C. elegans[/i]. / 01.08.2017 / PubMed / Full text

DUOX2

• Lifespan extension by peroxidase and dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in [i]C. elegans[/i]. / 01.08.2017 / PubMed / Full text

DUSP1

• miR-1468-3p Promotes Aging-Related Cardiac Fibrosis. / 05.06.2020 / PubMed / Full text

DUSP6

• Protection of CD4 T cells from hepatitis C virus infection-associated senescence via ΔNp63-miR-181a-Sirt1 pathway. / 11.2016 / PubMed / Full text

DUSP8

• MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats. / 12.2019 / PubMed / Full text

DUT

• Simultaneous liquefaction, saccharification, and fermentation of L-lactic acid using aging paddy rice with hull by an isolated thermotolerant Enterococcus faecalis DUT1805. / 09.2020 / PubMed / Full text

DVL1

• DNA methylation patterns associated with oxidative stress in an ageing population. / 25.11.2016 / PubMed / Full text

DYNC1H1

• Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age. / 10.2013 / PubMed / Full text

DYNC2H1

• Role for intraflagellar transport in building a functional transition zone. / 12.2018 / PubMed / Full text

DYNLT3

• Age-associated genes in human mammary gland drive human breast cancer progression. / 15.06.2020 / PubMed / Full text

ECE1

• Ferulic Acid Suppresses Amyloid [i]β[/i] Production in the Human Lens Epithelial Cell Stimulated with Hydrogen Peroxide. / 2017 / PubMed / Full text

ECRG4

• ECRG4: a new potential target in precision medicine. / 10.2019 / PubMed / Full text

ECSIT

• Longevity-related molecular pathways are subject to midlife "switch" in humans. / 08.2019 / PubMed / Full text

EDAR

• Pharmacological stimulation of Edar signaling in the adult enhances sebaceous gland size and function. / 02.2015 / PubMed / Full text

EDEM1

• Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text

EDF1

• Silencing of FOREVER YOUNG FLOWER Like Genes from Phalaenopsis Orchids Promotes Flower Senescence and Abscission. / 25.11.2020 / PubMed / Full text

EDNRA

• Variation in genes in the endothelin pathway and endothelium-dependent and endothelium-independent vasodilation in an elderly population. / 05.2013 / PubMed / Full text

EEA1

• Quantitative Immunoblotting Analyses Reveal that the Abundance of Actin, Tubulin, Synaptophysin and EEA1 Proteins is Altered in the Brains of Aged Mice. / 21.08.2020 / PubMed / Full text

EEF1A1

• Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells. / 01.04.2016 / PubMed / Full text

EEF2

• Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells. / 01.04.2016 / PubMed / Full text

EFCAB5

• Genetic architecture of epigenetic and neuronal ageing rates in human brain regions. / 18.05.2017 / PubMed / Full text

EFNB1

• Activation of EphA4 and EphB2 Reverse Signaling Restores the Age-Associated Reduction of Self-Renewal, Migration, and Actin Turnover in Human Tendon Stem/Progenitor Cells. / 2015 / PubMed / Full text

EFNB2

• Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo. / 15.03.2016 / PubMed / Full text

EGFEM1P

• Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip. / 10.2019 / PubMed / Full text

EGR2

• Age-related impairment of bones' adaptive response to loading in mice is associated with sex-related deficiencies in osteoblasts but no change in osteocytes. / 08.2014 / PubMed / Full text

EHMT1

• Two conserved epigenetic regulators prevent healthy ageing. / 03.2020 / PubMed / Full text

EID3

• Upregulation of EID3 sensitizes breast cancer cells to ionizing radiation-induced cellular senescence. / 11.2018 / PubMed / Full text

EIF2AK3

• The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease. / 06.07.2013 / PubMed / Full text

EIF2B2

• Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

EIF2B3

• Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

EIF2B4

• Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

EIF4E

• Transcriptomic evidence that insulin signalling pathway regulates the ageing of subterranean termite castes. / 18.05.2020 / PubMed / Full text

EIF4EBP1

• Peripheral Circulating Exosomal miRNAs Potentially Contribute to the Regulation of Molecular Signaling Networks in Aging. / 11.03.2020 / PubMed / Full text

ELANE

• Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text

ELK1

• Tocotrienol-rich fraction prevents cellular aging by modulating cell proliferation signaling pathways. / 2015 / PubMed / Full text

ELL

• Exceptional Longevity and Polygenic Risk for Cardiovascular Health. / 18.03.2019 / PubMed / Full text

ELN

• Curcumin enhances the production of major structural components of elastic fibers, elastin, and fibrillin-1, in normal human fibroblast cells. / 2015 / PubMed / Full text

ELOVL6

• An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. / 06.2019 / PubMed / Full text

EMILIN2

• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

EML6

• Cell fate regulation by reticulon-4 in human prostate cancers. / 07.2019 / PubMed / Full text

ENPEP

• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

ENTPD1

• Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation. / 01.07.2020 / PubMed / Full text

EPG5

• Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom. / 05.2018 / PubMed / Full text

EPHA3

• A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3. / 15.02.2013 / PubMed / Full text

EPHA7

• Impact of host ageing on the metastatic phenotype. / 03.2013 / PubMed / Full text

ERAP1

• Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

ERBB3

• [The expression of differential and matrix remodelling factors in human buccal epithelium in aging]. / 2013 / PubMed

ERBB4

• Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways. / 03.2019 / PubMed / Full text

ERCC2

• The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text

ERCC5

• Identification of a ERCC5 c.2333T>C (L778P) Variant in Two Tunisian Siblings With Mild Xeroderma Pigmentosum Phenotype. / 2019 / PubMed / Full text

ERCC8

• Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts. / 12.2019 / PubMed / Full text

EREG

• Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. / 07.2015 / PubMed / Full text

ERVK-7

• Effect of aging on the transcriptomic changes associated with the expression of the HERV-K (HML-2) provirus at 1q22. / 2020 / PubMed / Full text

ESCO1

• Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence. / 2015 / PubMed / Full text

ESPL1

• Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants. / 09.2020 / PubMed / Full text

ESRG

• MYC Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition. / 10.04.2018 / PubMed / Full text

ETFA

• Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone. / 07.2014 / PubMed / Full text

ETNK2

• In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text

ETV1

• Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects. / 09.2020 / PubMed / Full text

ETV5

• miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. / 06.2018 / PubMed / Full text

ETV6

• FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence. / 01.2019 / PubMed / Full text

EVC

• Decreased centrality of subcortical regions during the transition to adolescence: a functional connectivity study. / 01.01.2015 / PubMed / Full text

EVL

• Health Years in Total: A New Health Objective Function for Cost-Effectiveness Analysis. / 01.2020 / PubMed / Full text

EXD2

• EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. / 02.2018 / PubMed / Full text

EXOC3L2

• Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. / 04.2016 / PubMed / Full text

EXOC7

• PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. / 09.07.2018 / PubMed / Full text

EYA4

• A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records. / 10.2016 / PubMed / Full text

EYS

• Ablation of EYS in zebrafish causes mislocalisation of outer segment proteins, F-actin disruption and cone-rod dystrophy. / 05.04.2017 / PubMed / Full text

EZH1

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text

F10

• Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-F10 cells by inducing senescence. / 15.07.2018 / PubMed / Full text

F11

• A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. / 07.2013 / PubMed / Full text

F11R

• [Adhesion molecule JAM-A, its function and mechanism of epigenetic regulation]. / 2015 / PubMed

F12

• Multigenerational effects of carbendazim in Daphnia magna: From a subcellular to a population level. / 02.2019 / PubMed / Full text

FA2H

• C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production. / 2018 / PubMed / Full text

FADS2

• Genetic determinants of P wave duration and PR segment. / 08.2014 / PubMed / Full text

FAM13A

• Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. / 05.2018 / PubMed / Full text

FANCC

• Fanconi Anemia complementation group C protein in metabolic disorders. / 21.06.2018 / PubMed / Full text

FAT4

• Neuron-specific knockdown of the Drosophila fat induces reduction of life span, deficient locomotive ability, shortening of motoneuron terminal branches and defects in axonal targeting. / 07.2017 / PubMed / Full text

FBXO28

• MYC Modulation around the CDK2/p27/SKP2 Axis. / 30.06.2017 / PubMed / Full text

FBXO32

• Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System. / 18.10.2016 / PubMed / Full text

FBXO33

• Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids. / 25.09.2020 / PubMed / Full text

FBXO46

• The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence. / 19.10.2018 / PubMed / Full text

FBXO7

• The FBXO7 homologue nutcracker and binding partner PI31 in Drosophila melanogaster models of Parkinson's disease. / 01.2017 / PubMed / Full text

FBXW7

• MYC Modulation around the CDK2/p27/SKP2 Axis. / 30.06.2017 / PubMed / Full text

FCER1G

• A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. / 2019 / PubMed / Full text

FCGR2A

• Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells. / 03.08.2019 / PubMed / Full text

FCGR3A

• Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium. / 06.2015 / PubMed / Full text

FDPS

• Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes. / 12.2018 / PubMed / Full text

FDXR

• The aged testis. A good model to find proteins involved in age-related changes of testis by proteomic analysis. / 01-02.2014 / PubMed

FER

• Tracking the recognition of static and dynamic facial expressions of emotion across the life span. / 04.09.2018 / PubMed / Full text

FER1L6

• Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

FEZ1

• Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice. / 19.09.2017 / PubMed / Full text

FGB

• [Clinical and genetic characteristics of long-livers in Moscow region]. / 2013 / PubMed

FGF14

• Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus. / 12.2016 / PubMed / Full text

FGF7

• Prostatic microenvironment in senescence: fibroblastic growth factors × hormonal imbalance. / 05.2014 / PubMed / Full text

FGF8

• Prostatic microenvironment in senescence: fibroblastic growth factors × hormonal imbalance. / 05.2014 / PubMed / Full text

FGFBP1

• Muscle Fibers Secrete FGFBP1 to Slow Degeneration of Neuromuscular Synapses during Aging and Progression of ALS. / 04.01.2017 / PubMed / Full text

FGFR3

• New evidence for positive selection helps explain the paternal age effect observed in achondroplasia. / 15.10.2013 / PubMed / Full text

FGL2

• Developmental expression of B cell molecules in equine lymphoid tissues. / 01.2017 / PubMed / Full text

FICD

• Defining the limits of normal conjunctival fornix anatomy in a healthy South Asian population. / 02.2014 / PubMed / Full text

FIG4

• Knockdown of the Drosophila FIG4 induces deficient locomotive behavior, shortening of motor neuron, axonal targeting aberration, reduction of life span and defects in eye development. / 03.2016 / PubMed / Full text

FIGNL1

• Comparative proteomic analysis of primordial follicles from ovaries of immature and aged rats. / 2015 / PubMed / Full text

FKBP1A

• The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text

FKBP1B

• The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text

FKRP

• Progressive Dystrophic Pathology in Diaphragm and Impairment of Cardiac Function in FKRP P448L Mutant Mice. / 2016 / PubMed / Full text

FLCN

• Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner. / 08.2013 / PubMed / Full text

FLNA

• SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. / 02.10.2016 / PubMed / Full text

FLT3

• Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text

FLT4

• Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus. / 2020 / PubMed / Full text

FMN2

• Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium. / 06.2015 / PubMed / Full text

FMO1

• Functional analysis and transcriptional output of the Göttingen minipig genome. / 14.11.2015 / PubMed / Full text

FMO3

• Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver. / 11.2017 / PubMed / Full text

FNTA

• The Hip Morphology Changes with Ageing in Asian Population. / 2018 / PubMed / Full text

FOSL1

• RNA-Seq analysis reveals new evidence for inflammation-related changes in aged kidney. / 24.05.2016 / PubMed / Full text

FOSL2

• LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis. / 03.04.2020 / PubMed / Full text

FOXA3

• Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/SIRT1-FOXA3-Beclin1 pathway. / 01.10.2020 / PubMed / Full text

FOXD1

• MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1. / 12.2018 / PubMed / Full text

FOXP4

• Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization. / 06.11.2018 / PubMed / Full text

FRAS1

• FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk. / 2015 / PubMed / Full text

FREM3

• FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk. / 2015 / PubMed / Full text

FRG1

• Intergenerational response of steroidogenesis-related genes to maternal malnutrition. / 10.2019 / PubMed / Full text

FRG2

• Intergenerational response of steroidogenesis-related genes to maternal malnutrition. / 10.2019 / PubMed / Full text

FSHB

• Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. / 29.09.2015 / PubMed / Full text

FSTL5

• Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. / 12.2017 / PubMed / Full text

FTL

• Noncoding variation of the gene for ferritin light chain in hereditary and age-related cataract. / 2013 / PubMed / Full text

FZD1

• Frizzled-1 receptor regulates adult hippocampal neurogenesis. / 15.03.2016 / PubMed / Full text

FZD4

• MiR-1292 Targets FZD4 to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway. / 12.2018 / PubMed / Full text

G0S2

• Investigating the specific core genetic-and-epigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells. / 23.02.2016 / PubMed / Full text

G3BP1

• Dissecting the molecular mechanisms that impair stress granule formation in aging cells. / 03.2017 / PubMed / Full text

G6PC

• Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of TP53. / 11.2018 / PubMed / Full text

G6PC2

• Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS). / 04.2014 / PubMed / Full text

G6PC3

• Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text

GAB2

• Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936. / 01.12.2017 / PubMed / Full text

GABRR3

• Discovery of novel non-synonymous SNP variants in 988 candidate genes from 6 centenarians by target capture and next-generation sequencing. / 10.2013 / PubMed / Full text

GADD45B

• Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging? / 2019 / PubMed / Full text

GADD45G

• SIP1 is a downstream effector of GADD45G in senescence induction and growth inhibition of liver tumor cells. / 20.10.2015 / PubMed / Full text

GADD45GIP1

• Nucleus accumbens-1/GADD45GIP1 axis mediates cisplatin resistance through cellular senescence in ovarian cancer. / 06.2017 / PubMed / Full text

GAGE10

• An epigenome-wide association study of sex-specific chronological ageing. / 31.12.2019 / PubMed / Full text

GALNT18

• Genome-wide association study identifies [i]SIAH3[/i] locus influencing the rate of ventricular enlargement in non-demented elders. / 11.11.2019 / PubMed / Full text

GAR1

• Pseudouridylation defect due to [i]DKC1[/i] and [i]NOP10[/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. / 30.06.2020 / PubMed / Full text

GART

• Maintaining the continuity of HIV-care records for patients transferring care between centers: challenges, workloads, needs and risks. / 08.2016 / PubMed / Full text

GAS2

• Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53-mediated apoptosis. / 09.2015 / PubMed / Full text

GAST

• The effects of age and muscle contraction on AMPK activity and heterotrimer composition. / 07.2014 / PubMed / Full text

GATA1

• Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass. / 10.2019 / PubMed / Full text

GBA2

• Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease. / 08.11.2019 / PubMed / Full text

GBF1

• Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor GBF1. / 16.09.2015 / PubMed / Full text

GCGR

• Population pharmacokinetics and pharmacodynamics of IONIS-GCGR , an antisense oligonucleotide for type 2 diabetes mellitus: a red blood cell lifespan model. / 06.2017 / PubMed / Full text

GCH1

• Aging modifies the effect of GCH1 RS11158026 on DAT uptake and Parkinson's disease clinical severity. / 02.2017 / PubMed / Full text

GCNT2

• Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text

GDA

• Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces. / 03.2019 / PubMed / Full text

GDF5

• An embryonic CaVβ1 isoform promotes muscle mass maintenance via GDF5 signaling in adult mouse. / 06.11.2019 / PubMed / Full text

GEN1

• US acculturation and poor sleep among an intergenerational cohort of adult Latinos in Sacramento, California. / 01.03.2019 / PubMed / Full text

GFRA1

• Determination phase at transition of gonocytes to spermatogonial stem cells improves establishment efficiency of spermatogonial stem cells in domestic cats. / 2015 / PubMed / Full text

GFRAL

• Growth differentiation factor 15 (GDF15): A survival protein with therapeutic potential in metabolic diseases. / 06.2019 / PubMed / Full text

GGA3

• The pathological roles of NDRG2 in Alzheimer's disease, a study using animal models and APPwt-overexpressed cells. / 08.2017 / PubMed / Full text

GGCX

• Multiple Modes of Vitamin K Actions in Aging-Related Musculoskeletal Disorders. / 11.06.2019 / PubMed / Full text

GGT1

• Relation of size of seminal vesicles on ultrasound to premature ejaculation. / 09-10.2017 / PubMed / Full text

GIGYF1

• Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis. / 2015 / PubMed / Full text

GIGYF2

• Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis. / 2015 / PubMed / Full text

GJA3

• Down-regulation of GJA3 is associated with lens epithelial cell apoptosis and age-related cataract. / 26.02.2017 / PubMed / Full text

GJA8

• The impact of GJA8 SNPs on susceptibility to age-related cataract. / 12.2018 / PubMed / Full text

GJB2

• Reduced expression of Connexin26 and its DNA promoter hypermethylation in the inner ear of mimetic aging rats induced by d-galactose. / 26.09.2014 / PubMed / Full text

GJC2

• Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging. / 10.2020 / PubMed / Full text

GLP1R

• A nutrigenomics approach for the study of anti-aging interventions: olive oil phenols and the modulation of gene and microRNA expression profiles in mouse brain. / 03.2017 / PubMed / Full text

GLRA1

• Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model. / 03.2016 / PubMed / Full text

GLRA2

• Gene Expression Switching of Receptor Subunits in Human Brain Development. / 12.2015 / PubMed / Full text

GLRA3

• Gene Expression Switching of Receptor Subunits in Human Brain Development. / 12.2015 / PubMed / Full text

GMDS

• Validity and clinical utilization of the Chinese version of the Gotland Male Depression Scale at a men's health polyclinic. / 2014 / PubMed / Full text

GML

• Age independently affects myelin integrity as detected by magnetization transfer magnetic resonance imaging in multiple sclerosis. / 2014 / PubMed / Full text

GNA11

• GNAQ expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system. / 01.2020 / PubMed / Full text

GNA14

• Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle. / 29.06.2017 / PubMed / Full text

GNG11

• GNG11 (G-protein subunit γ 11) suppresses cell growth with induction of reactive oxygen species and abnormal nuclear morphology in human SUSM-1 cells. / 08.2017 / PubMed / Full text

GNG4

• Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes. / 05.2018 / PubMed / Full text

GNPAT

• Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells. / 05.2019 / PubMed / Full text

GNPDA2

• The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study. / 05.2013 / PubMed / Full text

GNRH2

• Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. / 2015 / PubMed / Full text

GORAB

• Examining tissue composition, whole-bone morphology and mechanical behavior of Gorab mice tibiae: A mouse model of premature aging. / 08.12.2017 / PubMed / Full text

GOT1

• Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text

GOT2

• An integrated metabolomic and gene expression analysis identifies heat and calcium metabolic networks underlying postharvest sweet cherry fruit senescence. / 12.2019 / PubMed / Full text

GP1BA

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

GP9

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

GPBAR1

• Activation of the bile acid receptor GPBAR1 (TGR5) ameliorates interleukin-1β (IL-1β)- induced chondrocytes senescence. / 10.2018 / PubMed / Full text

GPC1

• Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing. / 15.10.2019 / PubMed / Full text

GPD1

• The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. / 01.08.2015 / PubMed / Full text

GPD2

• Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. / 06.2018 / PubMed / Full text

GPR1

• The Arabidopsis GPR1 Gene Negatively Affects Pollen Germination, Pollen Tube Growth, and Gametophyte Senescence. / 21.06.2017 / PubMed / Full text

GPR101

• Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent. / 2017 / PubMed / Full text

GPR173

• Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent. / 2017 / PubMed / Full text

GPR19

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

GPR37

• Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. / 08.2018 / PubMed / Full text

GPR37L1

• Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. / 08.2018 / PubMed / Full text

GPR4

• The proton-activated receptor GPR4 modulates glucose homeostasis by increasing insulin sensitivity. / 2013 / PubMed / Full text

GPR6

• Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy. / 22.09.2020 / PubMed / Full text

GPR78

• A meta-analysis of genome-wide association studies identifies multiple longevity genes. / 14.08.2019 / PubMed / Full text

GPRC5C

• Anti-diabetic action of all-trans retinoic acid and the orphan G protein coupled receptor GPRC5C in pancreatic β-cells. / 31.03.2017 / PubMed / Full text

GPX3

• Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract. / 2019 / PubMed / Full text

GPX7

• Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7. / 08.2018 / PubMed / Full text

GREM1

• GREM1 inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. / 09.03.2020 / PubMed / Full text

GREM2

• Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis. / 12.2019 / PubMed / Full text

GRIA1

• Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models. / 30.03.2017 / PubMed / Full text

GRID1

• Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. / 03.2020 / PubMed / Full text

GRIN2A

• Gene Expression Switching of Receptor Subunits in Human Brain Development. / 12.2015 / PubMed / Full text

GRINA

• Genome-wide association study for lactation persistency, female fertility, longevity, and lifetime profit index traits in Holstein dairy cattle. / 02.2017 / PubMed / Full text

GRK4

• G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text

GRK6

• Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity. / 12.2019 / PubMed / Full text

GRM2

• Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

GRM6

• Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics. / 08.06.2016 / PubMed / Full text

GRP

• A new approach to quantifying the EEG during walking: Initial evidence of gait related potentials and their changes with aging and dual tasking. / 15.10.2019 / PubMed / Full text

GRPR

• Gastrin-Releasing Peptide Receptor Knockdown Induces Senescence in Glioblastoma Cells. / 03.2017 / PubMed / Full text

GSN

• Oral administration of alcalase potato protein hydrolysate-APPH attenuates high fat diet-induced cardiac complications via TGF-β/GSN axis in aging rats. / 01.2019 / PubMed / Full text

GSTA3

• Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice. / 2014 / PubMed / Full text

GSTM2

• Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage. / 07.07.2020 / PubMed / Full text

GSTO1

• Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GSTT2

• Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GTF3C4

• A multidimensional systems biology analysis of cellular senescence in aging and disease. / 07.04.2020 / PubMed / Full text

GTSF1

• Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes. / 01.2016 / PubMed / Full text

GUK1

• Characterization of the impact of GMP/GDP synthesis inhibition on replicative lifespan extension in yeast. / 08.2020 / PubMed / Full text

GUSB

• Identification of reference genes for RT-qPCR data normalisation in aging studies. / 27.09.2019 / PubMed / Full text

GYS2

• In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers. / 04.2018 / PubMed / Full text

GZMH

• Age-related profiling of DNA methylation in CD8 T cells reveals changes in immune response and transcriptional regulator genes. / 19.08.2015 / PubMed / Full text

GZMK

• Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK CD8 T Cells as Conserved Hallmark of Inflammaging. / 21.11.2020 / PubMed / Full text

HABP4

• Microneedle fractional radiofrequency increases epidermal hyaluronan and reverses age-related epidermal dysfunction. / 02.2016 / PubMed / Full text

HACE1

• HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response. / 25.02.2014 / PubMed / Full text

HADH

• Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone. / 07.2014 / PubMed / Full text

HADHA

• Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells. / 2019 / PubMed / Full text

HAMP

• A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity. / 04.2018 / PubMed / Full text

HAP1

• The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer. / 20.06.2018 / PubMed / Full text

HAUS4

• A multidimensional systems biology analysis of cellular senescence in aging and disease. / 07.04.2020 / PubMed / Full text

HAX1

• Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text

HBM

• The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis. / 25.09.2019 / PubMed / Full text

HBZ

• HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and HBZ. / 16.06.2016 / PubMed / Full text

HDAC10

• Middle-aged female rats lack changes in histone H3 acetylation in the anterior hypothalamus observed in young females on the day of a luteinizing hormone surge. / 17.09.2019 / PubMed / Full text

HDAC11

• Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice. / 19.09.2017 / PubMed / Full text

HDAC8

• Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri. / 09.2018 / PubMed / Full text

HDC

• Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells. / 07.05.2020 / PubMed / Full text

HDX

• Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence. / 28.12.2016 / PubMed / Full text

HEPN1

• Functional analysis and transcriptional output of the Göttingen minipig genome. / 14.11.2015 / PubMed / Full text

HERC2

• Endothelial SIRT1 prevents adverse arterial remodeling by facilitating HERC2-mediated degradation of acetylated LKB1. / 28.06.2016 / PubMed / Full text

HGSNAT

• Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC. / 01.09.2016 / PubMed / Full text

HHIP

• Hhip haploinsufficiency sensitizes mice to age-related emphysema. / 09.08.2016 / PubMed / Full text

HHLA2

• Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma. / 05.2019 / PubMed / Full text

HIF3A

• Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text

HIP1

• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

HIPK2

• Nore1a drives Ras to flick the P53 senescence switch. / 05.2016 / PubMed / Full text

HJURP

• HJURP regulates cellular senescence in human fibroblasts and endothelial cells via a p53-dependent pathway. / 08.2013 / PubMed / Full text

HJV

• Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting. / 06.2019 / PubMed / Full text

HLA-DMA

• Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

HLA-DPA1

• 17th IHIW component "Immunogenetics of Ageing" - New NGS data. / 09.2019 / PubMed / Full text

HLA-DRA

• Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. / 24.02.2016 / PubMed / Full text

HLA-DRB4

• Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text

HLA-DRB5

• Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study. / 2017 / PubMed / Full text

HLA-E

• Senescent cells evade immune clearance via HLA-E-mediated NK and CD8 T cell inhibition. / 03.06.2019 / PubMed / Full text

HLA-F

• Extended lifespan and reduced adiposity in mice lacking the FAT10 gene. / 08.04.2014 / PubMed / Full text

HLF

• Healthy lifestyle and normal waist circumference are associated with a lower 5-year risk of type 2 diabetes in middle-aged and elderly individuals: Results from the healthy aging longitudinal study in Taiwan (HALST). / 02.2017 / PubMed / Full text

HMGCS2

• The aged testis. A good model to find proteins involved in age-related changes of testis by proteomic analysis. / 01-02.2014 / PubMed

HMGN2

• FAM96B inhibits the senescence of dental pulp stem cells. / 05.2020 / PubMed / Full text

HMMR

• The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations. / 15.12.2014 / PubMed / Full text

HMX1

• Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence. / 28.12.2016 / PubMed / Full text

HNF1A

• The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing. / 12.2019 / PubMed / Full text

HNMT

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

HNRNPA0

• The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. / 10.2019 / PubMed / Full text

HNRNPA2B1

• Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans. / 10.2016 / PubMed / Full text

HNRNPF

• Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text

HNRNPM

• The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. / 10.2019 / PubMed / Full text

HOXA3

• DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

HOXA4

• Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes. / 10.2019 / PubMed / Full text

HOXA9

• Co-regulation of senescence-associated genes by oncogenic homeobox proteins and polycomb repressive complexes. / 15.07.2013 / PubMed / Full text

HOXB7

• Impact of HOXB7 overexpression on human adipose-derived mesenchymal progenitors. / 19.03.2019 / PubMed / Full text

HOXC13

• Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence. / 28.12.2016 / PubMed / Full text

HOXD8

• Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts. / 2020 / PubMed / Full text

HP1BP3

• Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging. / 10.2016 / PubMed / Full text

HPDL

• Characterization and cytological effects of a novel glycated gelatine substrate. / 04.2014 / PubMed / Full text

HPSE

• Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin. / 07.2020 / PubMed / Full text

HRC

• Differences in false recollection according to the cognitive reserve of healthy older people. / 09.2016 / PubMed / Full text

HRH4

• Histamime Receptor H4 as a New Therapeutic Target for Age-related Macular Degeneration. / 11.2016 / PubMed

HS2ST1

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

HSD17B1

• Genetic Basis of the Relationship Between Reproduction and Longevity: A Study on Common Variants of Three Genes in Steroid Hormone Metabolism--CYP17, HSD17B1, and COMT. / 10.2015 / PubMed / Full text

HSD17B14

• Bisphenol A induces DSB-ATM-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts. / 04.2018 / PubMed / Full text

HSD17B4

• Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein-2 deficiency. / 09.2018 / PubMed / Full text

HSPA13

• Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

HSPA1L

• Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L-mitophagy pathway. / 03.2020 / PubMed / Full text

HSPA4

• Assessment of the risk of blastomere biopsy during preimplantation genetic diagnosis in a mouse model: reducing female ovary function with an increase in age by proteomics method. / 06.12.2013 / PubMed / Full text

HSPA5

• Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text

HSPBP1

• BAG2 Interferes with CHIP-Mediated Ubiquitination of HSP72. / 30.12.2016 / PubMed / Full text

HSPG2

• Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

HTR1A

• Gene Expression Switching of Receptor Subunits in Human Brain Development. / 12.2015 / PubMed / Full text

HTR1B

• Polymorphic variants of neurotransmitter receptor genes may affect sexual function in aging males: data from the HALS study. / 2013 / PubMed / Full text

HTR2A

• Region-specific regulation of the serotonin 2A receptor expression in development and ageing in post mortem human brain. / 06.2015 / PubMed / Full text

HTR2B

• Up-regulation of serotonin receptor 2B mRNA and protein in the peri-infarcted area of aged rats and stroke patients. / 05.04.2016 / PubMed / Full text

HTR4

• ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text

HTR5A

• Gene Expression Switching of Receptor Subunits in Human Brain Development. / 12.2015 / PubMed / Full text

HTRA2

• A novel role for the mitochondrial HTRA2/OMI protease in aging. / 03.2013 / PubMed / Full text

HYOU1

• Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text

IBSP

• P4 medicine and osteoporosis: a systematic review. / 12.2016 / PubMed / Full text

ICAM5

• A reverse genetics cell-based evaluation of genes linked to healthy human tissue age. / 01.2017 / PubMed / Full text

ICE1

• ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1. / 19.02.2020 / PubMed / Full text

IFI27

• Ultraviolet B irradiation-induced keratinocyte senescence and impaired development of 3D epidermal reconstruct. / 01.06.2021 / PubMed / Full text

IFIH1

• Comparative analysis of microbial sensing molecules in mucosal tissues with aging. / 03.2018 / PubMed / Full text

IFNAR2

• Type I interferon receptors in goose: molecular cloning, structural identification, evolutionary analysis and age-related tissue expression profile. / 25.04.2015 / PubMed / Full text

IFNB1

• Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa. / 02.2016 / PubMed / Full text

IFNGR2

• Lifespan of mice and primates correlates with immunoproteasome expression. / 05.2015 / PubMed / Full text

IFT140

• The Role of IFT140 in Osteogenesis of Adult Mice Long Bone. / 08.2019 / PubMed / Full text

IGF2BP2

• Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. / 01.2016 / PubMed / Full text

IGF2BP3

• Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth. / 01.05.2019 / PubMed / Full text

IGFBP6

• Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

IGHG2

• Human IgG2- and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age. / 10.2017 / PubMed / Full text

IGHM

• Developmental expression of B cell molecules in equine lymphoid tissues. / 01.2017 / PubMed / Full text

IGLL5

• Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution. / 07.12.2015 / PubMed / Full text

IKBKB

• Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

IL10RA

• Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease. / 11.2015 / PubMed / Full text

IL11

• Myocardial Infarction Superimposed on Aging: MMP-9 Deletion Promotes M2 Macrophage Polarization. / 04.2016 / PubMed / Full text

IL12B

• Association and Interaction Effects of Interleukin-12 Related Genes and Physical Activity on Cognitive Aging in Old Adults in the Taiwanese Population. / 2019 / PubMed / Full text

IL13RA1

• Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle. / 29.06.2017 / PubMed / Full text

IL17C

• Age-dependent changes in inflammation and extracellular matrix in bovine oviduct epithelial cells during the post-ovulatory phase. / 09.2016 / PubMed / Full text

IL17D

• Genetic determinants of P wave duration and PR segment. / 08.2014 / PubMed / Full text

IL17RA

• Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon. / 2017 / PubMed / Full text

IL17RB

• Identification of genes associated with endometrial cell aging. / 01.12.2020 / PubMed / Full text

IL17RC

• Overstimulation can create health problems due to increases in PI3K/Akt/GSK3 insensitivity and GSK3 activity. / 2014 / PubMed / Full text

IL18RAP

• Age and pro-inflammatory gene polymorphisms influence adjacent segment disc degeneration more than fusion does in patients treated for chronic low back pain. / 01.2016 / PubMed / Full text

IL1R2

• Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin. / 01.2018 / PubMed / Full text

IL1RN

• Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90 study. / 08.2015 / PubMed / Full text

IL21

• The expression of IL6 and 21 in crossbred calves upregulated by inactivated trivalent FMD vaccine. / 03.04.2014 / PubMed / Full text

IL22

• Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text

IL2RA

• Dynamic demethylation of the IL2RA promoter during in vitro CD4 T cell activation in association with IL2RA expression. / 2018 / PubMed / Full text

IL2RG

• Generation of a Nonhuman Primate Model of Severe Combined Immunodeficiency Using Highly Efficient Genome Editing. / 07.07.2016 / PubMed / Full text

IL33

• Interleukin33 deficiency causes tau abnormality and neurodegeneration with Alzheimer-like symptoms in aged mice. / 04.07.2017 / PubMed / Full text

IL36RN

• Elderly-Onset Generalized Pustular Psoriasis without a Previous History of Psoriasis Vulgaris. / 05-08.2015 / PubMed / Full text

IL5

• Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro. / 04.02.2020 / PubMed / Full text

IL6ST

• The senescent status of endothelial cells affects proliferation, inflammatory profile and SOX2 expression in bone marrow-derived mesenchymal stem cells. / 06.2019 / PubMed / Full text

IMMP2L

• Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. / 06.2018 / PubMed / Full text

IMMT

• A multidimensional systems biology analysis of cellular senescence in aging and disease. / 07.04.2020 / PubMed / Full text

IMPA1

• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

IMPA2

• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

INHBA

• Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

INHBE

• Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text

INO80D

• Whole exome sequencing implicates an INO80D mutation in a syndrome of aortic hypoplasia, premature atherosclerosis, and arterial stiffness. / 10.2014 / PubMed / Full text

INPP4B

• [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text

INPPL1

• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

IP6K1

• The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle. / 2019 / PubMed / Full text

IP6K3

• Inositol Hexakisphosphate Kinase 3 Regulates Metabolism and Lifespan in Mice. / 31.08.2016 / PubMed / Full text

IPMK

• Inositol Polyphosphate Multikinase ([i]IPMK[/i]), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity. / 08.02.2019 / PubMed / Full text

IRAK1

• Age-associated changes in microRNA expression in bone marrow derived dendritic cells. / 2013 / PubMed / Full text

IRAK4

• The Expression Changes of Inflammasomes in the Aging Rat Kidneys. / 06.2016 / PubMed / Full text

IRF1

• Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text

IRF5

• Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice. / 11.2017 / PubMed / Full text

IRF9

• Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2. / 2020 / PubMed / Full text

IRX2

• Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence. / 28.12.2016 / PubMed / Full text

ISG20

• A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records. / 10.2016 / PubMed / Full text

ISYNA1

• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

ITCH

• Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing. / 11.2015 / PubMed / Full text

ITGA2

• [Clinical and genetic characteristics of long-livers in Moscow region]. / 2013 / PubMed

ITGA3

• A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells. / 17.08.2020 / PubMed / Full text

ITGA5

• Kaempferol alleviates the reduction of developmental competence during aging of porcine oocytes. / 11.2019 / PubMed / Full text

ITGA6

• Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text

ITGA8

• Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging. / 2019 / PubMed / Full text

ITGB1

• Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report. / 05.2018 / PubMed / Full text

ITGB4

• ITGB4 deficiency induces senescence of airway epithelial cells through p53 activation. / 03.2019 / PubMed / Full text

ITGB5

• Differential DNA Methylation in Relation to Age and Health Risks of Obesity. / 24.07.2015 / PubMed / Full text

ITM2B

• Intramembrane proteolysis within lysosomes. / 12.2016 / PubMed / Full text

ITPKB

• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

ITPR1

• Age-associated repression of type 1 inositol 1, 4, 5-triphosphate receptor impairs muscle regeneration. / 21.09.2016 / PubMed / Full text

ITPR2

• The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling. / 12.2018 / PubMed / Full text

JAG1

• Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. / 01.12.2016 / PubMed / Full text

JAGN1

• Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text

JAM3

• Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text

JARID2

• Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

JDP2

• Jun dimerization protein 2 controls hypoxia-induced replicative senescence via both the p16 -pRb and Arf-p53 pathways. / 11.2017 / PubMed / Full text

JHY

• Disruption of the mouse Jhy gene causes abnormal ciliary microtubule patterning and juvenile hydrocephalus. / 01.10.2013 / PubMed / Full text

JMJD1C

• JMJD1C, a JmjC domain-containing protein, is required for long-term maintenance of male germ cells in mice. / 10.2013 / PubMed / Full text

JUNB

• Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of JUNB. / 19.02.2020 / PubMed / Full text

JUP

• From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration. / 22.11.2016 / PubMed / Full text

KALRN

• Age-dependent increase in Kalirin-9 and Kalirin-12 transcripts in human orbitofrontal cortex. / 10.2016 / PubMed / Full text

KANSL1

• Koolen-de Vries Syndrome: Clinical Report of an Adult and Literature Review. / 2016 / PubMed / Full text

KAT6B

• Aging-associated decrease in the histone acetyltransferase KAT6B is linked to altered hematopoietic stem cell differentiation. / 02.2020 / PubMed / Full text

KCNAB3

• Tracking age-correlated DNA methylation markers in the young. / 09.2018 / PubMed / Full text

KCNC3

• DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird. / 2017 / PubMed / Full text

KCNC4

• Targeted deletion of [i]Kcne3[/i] impairs skeletal muscle function in mice. / 07.2017 / PubMed / Full text

KCND3

• Genetic determinants of P wave duration and PR segment. / 08.2014 / PubMed / Full text

KCNE1

• Delayed pharyngeal repolarization promotes abnormal calcium buildup in aging muscle. / 12.04.2013 / PubMed / Full text

KCNE3

• Targeted deletion of [i]Kcne3[/i] impairs skeletal muscle function in mice. / 07.2017 / PubMed / Full text

KCNE4

• Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice. / 29.05.2018 / PubMed / Full text

KCNH2

• Targeted deletion of [i]Kcne3[/i] impairs skeletal muscle function in mice. / 07.2017 / PubMed / Full text

KCNJ10

• Compromised potassium recycling in the cochlea contributes to conservation of endocochlear potential in a mouse model of age-related hearing loss. / 25.10.2013 / PubMed / Full text

KCNJ11

• A mouse model of human hyperinsulinism produced by the E1506K mutation in the sulphonylurea receptor SUR1. / 11.2013 / PubMed / Full text

KCNJ12

• Altered expression of genes for Kir ion channels in dilated cardiomyopathy. / 08.2013 / PubMed / Full text

KCNJ14

• Altered expression of genes for Kir ion channels in dilated cardiomyopathy. / 08.2013 / PubMed / Full text

KCNJ2

• Altered expression of genes for Kir ion channels in dilated cardiomyopathy. / 08.2013 / PubMed / Full text

KCNJ4

• Altered expression of genes for Kir ion channels in dilated cardiomyopathy. / 08.2013 / PubMed / Full text

KCNJ6

• Genetic correlates of the development of theta event related oscillations in adolescents and young adults. / 05.2017 / PubMed / Full text

KCNK2

• Brain age prediction using deep learning uncovers associated sequence variants. / 27.11.2019 / PubMed / Full text

KCNK4

• Targeted deletion of [i]Kcne3[/i] impairs skeletal muscle function in mice. / 07.2017 / PubMed / Full text

KCNQ1

• Compromised potassium recycling in the cochlea contributes to conservation of endocochlear potential in a mouse model of age-related hearing loss. / 25.10.2013 / PubMed / Full text

KCNQ1DN

• The EpiTect Methyl qPCR Assay as novel age estimation method in forensic biology. / 07.2016 / PubMed / Full text

KCNQ2

• Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes. / 05.2018 / PubMed / Full text

KCNQ4

• Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss. / 2020 / PubMed / Full text

KCNS3

• Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. / 25.11.2013 / PubMed / Full text

KCP

• The kielin/chordin-like protein KCP attenuates nonalcoholic fatty liver disease in mice. / 01.10.2016 / PubMed / Full text

KCTD12

• The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort. / 2020 / PubMed / Full text

KDF1

• The histological characteristics, age-related thickness change of skin, and expression of the HSPs in the skin during hair cycle in yak (Bos grunniens). / 2017 / PubMed / Full text

KDM1A

• Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations. / 2020 / PubMed / Full text

KDM2A

• SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. / 25.06.2020 / PubMed / Full text

KDM4A

• Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines. / 15.01.2019 / PubMed / Full text

KDM5A

• Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines. / 15.01.2019 / PubMed / Full text

KDM5B

• Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases. / 03.2016 / PubMed / Full text

KDR

• Regulation of endothelial progenitor cell differentiation and function by dimethylarginine dimethylaminohydrolase 2 in an asymmetric dimethylarginine-independent manner. / 09.2014 / PubMed / Full text

KIAA0319

• The Dyslexia-susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling. / 01.03.2017 / PubMed / Full text

KIAA0930

• Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach. / 23.10.2020 / PubMed / Full text

KIAA1755

• Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip. / 10.2019 / PubMed / Full text

KIF11

• Bmk-1 regulates lifespan in Caenorhabditis elegans by activating hsp-16. / 07.08.2015 / PubMed / Full text

KIF1A

• SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

KIF3A

• Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease. / 01.09.2014 / PubMed / Full text

KIF4A

• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

KIF5C

• Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis. / 2016 / PubMed / Full text

KIF6

• Gene variants at FTO, 9p21, and 2q36.3 are age-independently associated with myocardial infarction in Czech men. / 15.02.2016 / PubMed / Full text

KIR3DL2

• Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply. / 04.2014 / PubMed / Full text

KLB

• Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. / 2018 / PubMed / Full text

KLF1

• Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis. / 24.08.2018 / PubMed / Full text

KLF10

• Polymorphism rs7278468 is associated with Age-related cataract through decreasing transcriptional activity of the CRYAA promoter. / 17.03.2016 / PubMed / Full text

KLF2

• KLF2 induces the senescence of pancreatic cancer cells by cooperating with FOXO4 to upregulate p21. / 01.03.2020 / PubMed / Full text

KLHL13

• Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle. / 29.06.2017 / PubMed / Full text

KLHL22

• KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text

KPNA5

• Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence. / 2015 / PubMed / Full text

KRR1

• Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. / 29.09.2015 / PubMed / Full text

KRT15

• Extracellular proteoglycan decorin maintains human hair follicle stem cells. / 12.2018 / PubMed / Full text

KRT18

• Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text

KRT19

• Characterization of Krt19 allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc. / 01.2020 / PubMed / Full text

KRT5

• Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells. / 04.2017 / PubMed / Full text

KTN1

• Common genetic variants influence human subcortical brain structures. / 09.04.2015 / PubMed / Full text

KY

• Combination of acupuncture and Chinese herbal formula for elderly adults with mild cognitive impairment: protocol for a randomized controlled trial. / 11.02.2019 / PubMed / Full text

L3MBTL1

• Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis. / 12.2015 / PubMed / Full text

LAGE3

• Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text

LAMA1

• Laminin α1 regulates age-related mesangial cell proliferation and mesangial matrix accumulation through the TGF-β pathway. / 06.2014 / PubMed / Full text

LAMA2

• [Alu insertion-deletion polymorphism of COL13A1 and LAMA2 genes: The analysis of association with longevity]. / 10.2016 / PubMed

LATS1

• Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2. / 01.2017 / PubMed / Full text

LDB2

• Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

LDHC

• The aged testis. A good model to find proteins involved in age-related changes of testis by proteomic analysis. / 01-02.2014 / PubMed

LDLRAD4

• Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients. / 10.2020 / PubMed / Full text

LEF1

• LncRNA H19 targets miR-22 to modulate H O -induced deregulation in nucleus pulposus cell senescence, proliferation, and ECM synthesis through Wnt signaling. / 06.2018 / PubMed / Full text

LGALS1

• Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers. / 08.10.2013 / PubMed / Full text

LGALS3

• Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. / 2018 / PubMed / Full text

LGR6

• Effect of defensins-containing eye cream on periocular rhytids and skin quality. / 08.2020 / PubMed / Full text

LIMK2

• Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1. / 01-02.2017 / PubMed / Full text

LINC00862

• Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. / 12.2017 / PubMed / Full text

LIPC

• Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids. / 25.09.2020 / PubMed / Full text

LIPG

• Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids. / 25.09.2020 / PubMed / Full text

LMNB2

• Physiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear Edge. / 2016 / PubMed / Full text

LMO2

• Aging-dependent DNA hypermethylation and gene expression of GSTM1 involved in T cell differentiation. / 25.07.2017 / PubMed / Full text

LMX1A

• Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain. / 13.11.2018 / PubMed / Full text

LMX1B

• LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys. / 11.2013 / PubMed / Full text

LOXL4

• Blood Vessel Basement Membrane Alterations in Human Retinal Microaneurysms During Aging. / 01.02.2017 / PubMed / Full text

LPAR3

• Upregulated microRNA-15b alleviates ovarian cancer through inhitbition of the PI3K/Akt pathway by targeting LPAR3. / 12.2019 / PubMed / Full text

LRAT

• Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells. / 04.2014 / PubMed / Full text

LRCH1

• Genetic determinants of P wave duration and PR segment. / 08.2014 / PubMed / Full text

LRP2

• Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis. / 27.11.2018 / PubMed / Full text

LRP8

• SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE. / 02.07.2019 / PubMed / Full text

LRRC23

• Common genetic variants in ARNTL and NPAS2 and at chromosome 12p13 are associated with objectively measured sleep traits in the elderly. / 01.03.2013 / PubMed / Full text

LRRC34

• The polygenic nature of telomere length and the anti-ageing properties of lithium. / 03.2019 / PubMed / Full text

LRRC8B

• DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

LRRK1

• Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice. / 15.11.2017 / PubMed / Full text

LTBP4

• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

LY6D

• LY6D-induced macropinocytosis as a survival mechanism of senescent cells. / 09.11.2020 / PubMed / Full text

LY86

• Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. / 09.2019 / PubMed / Full text

LYG1

• Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text

LYST

• Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text

MACROD2

• Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects. / 09.2020 / PubMed / Full text

MADD

• Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text

MAFB

• Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy. / 01.04.2019 / PubMed / Full text

MAGOHB

• Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescence. / 14.10.2015 / PubMed / Full text

MAK

• Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH. / 11.2020 / PubMed / Full text

MANBA

• A meta-analysis of genome-wide association studies of epigenetic age acceleration. / 11.2019 / PubMed / Full text

MANF

• Age-dependent decrease in chaperone activity impairs MANF expression, leading to Purkinje cell degeneration in inducible SCA17 mice. / 22.01.2014 / PubMed / Full text

MAOB

• Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations. / 2020 / PubMed / Full text

MAP2K3

• Associations of [i]MAP2K3[/i] Gene Variants With Superior Memory in SuperAgers. / 2018 / PubMed / Full text

MAP3K11

• Aberrant DNA Methylation in Keratoacanthoma. / 2016 / PubMed / Full text

MAP3K5

• Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. / 08.10.2018 / PubMed / Full text

MAP4K3

• MAP4K3/GLK in autoimmune disease, cancer and aging. / 22.10.2019 / PubMed / Full text

MAPK10

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

MAPK11

• lncRNA ENSMUST00000134285 Increases MAPK11 Activity, Regulating Aging-Related Myocardial Apoptosis. / 09.07.2018 / PubMed / Full text

MAPK13

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

MAPK8

• Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

MARCKSL1

• MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors. / 04.2018 / PubMed / Full text

MARK1

• SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

MARK4

• Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer. / 01.2020 / PubMed / Full text

MAS1

• AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation. / 17.04.2018 / PubMed / Full text

MASP1

• Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44. / 2013 / PubMed / Full text

MATN2

• Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis. / 19.01.2020 / PubMed / Full text

MATN3

• Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis. / 19.01.2020 / PubMed / Full text

MATN4

• Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis. / 19.01.2020 / PubMed / Full text

MATR3

• Heterogeneity of Matrin 3 in the developing and aging murine central nervous system. / 01.10.2016 / PubMed / Full text

MBD2

• Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords. / 02.2019 / PubMed / Full text

MBOAT2

• Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. / 03.2020 / PubMed / Full text

MBTD1

• LncRNA TTN-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis. / 10.10.2019 / PubMed / Full text

MCF2L

• DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

MCM3AP

• Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer's disease animal model. / 2013 / PubMed / Full text

MCM5

• Changes in MCM2-7 proteins at senescence. / 27.07.2019 / PubMed / Full text

MCM6

• Changes in MCM2-7 proteins at senescence. / 27.07.2019 / PubMed / Full text

MCUR1

• Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. / 09.2019 / PubMed / Full text

MDK

• A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text

MDN1

• Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text

ME3

• Acceleration of age-associated methylation patterns in HIV-1-infected adults. / 2015 / PubMed / Full text

MECOM

• Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease. / 11.2018 / PubMed / Full text

MED25

• The [i]HAC1[/i] histone acetyltransferase promotes leaf senescence and regulates the expression of [i]ERF022[/i]. / 08.2019 / PubMed / Full text

MED28

• Redox regulation of the MED28 and MED32 mediator subunits is important for development and senescence. / 05.2016 / PubMed / Full text

MEIS2

• Pbx1 is required for adult subventricular zone neurogenesis. / 01.07.2016 / PubMed / Full text

MEPE

• Remodeling process in bone of aged rats in response to resistance training. / 01.09.2020 / PubMed / Full text

MERTK

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

MESP1

• Simulated Microgravity Exerts an Age-Dependent Effect on the Differentiation of Cardiovascular Progenitors Isolated from the Human Heart. / 2015 / PubMed / Full text

MEST

• Improving specific autobiographical memory in older adults: impacts on mood, social problem solving, and functional limitations. / 09.2018 / PubMed / Full text

MFAP4

• The role of microfibrillar-associated protein 4 (MFAP4) in the formation and function of splenic compartments during embryonic and adult life. / 07.2016 / PubMed / Full text

MFSD2A

• Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease. / 20.12.2019 / PubMed / Full text

MICB

• Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

MICU1

• Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. / 09.2019 / PubMed / Full text

MIPEP

• [Metabolic Alteration in Aging Process: Metabolic Remodeling in White Adipose Tissue by Caloric Restriction]. / 2020 / PubMed / Full text

MKRN1

• Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. / 11.2019 / PubMed / Full text

MLH3

• Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes. / 19.10.2017 / PubMed / Full text

MLST8

• Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum. / 02.02.2016 / PubMed / Full text

MMP20

• Identification of the effects of aging-related gene-matrix metalloproteinase on allograft outcomes in kidney transplantation. / 07-08.2013 / PubMed / Full text

MOB1B

• Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text

MOG

• Efficacy of vitamin D in treating multiple sclerosis-like neuroinflammation depends on developmental stage. / 11.2013 / PubMed / Full text

MORF4L1

• A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text

MPC1

• Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training. / 01.07.2016 / PubMed / Full text

MPG

• Menoprogen, a TCM Herbal Formula for Menopause, Increases Endogenous E2 in an Aged Rat Model of Menopause by Reducing Ovarian Granulosa Cell Apoptosis. / 2016 / PubMed / Full text

MPHOSPH6

• Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text

MPL

• Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender. / 10.2017 / PubMed / Full text

MPP3

• MPP3 regulates levels of PALS1 and adhesion between photoreceptors and Müller cells. / 10.2013 / PubMed / Full text

MPP4

• DNA damage tolerance in hematopoietic stem and progenitor cells in mice. / 15.08.2017 / PubMed / Full text

MPST

• Methionine restriction leads to hyperhomocysteinemia and alters hepatic H S production capacity in Fischer-344 rats. / 12.2018 / PubMed / Full text

MPV17

• The Human Mitochondrial DNA Depletion Syndrome Gene MPV17 Encodes a Non-selective Channel That Modulates Membrane Potential. / 29.05.2015 / PubMed / Full text

MR1

• Human blood MAIT cell subsets defined using MR1 tetramers. / 05.2018 / PubMed / Full text

MRC1

• Myocardial Infarction Superimposed on Aging: MMP-9 Deletion Promotes M2 Macrophage Polarization. / 04.2016 / PubMed / Full text

MRO

• [Effects of different intensities exercise combined with resveratrol on RBP4 in aged obese rats]. / 08.05.2017 / PubMed / Full text

MRTFA

• Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse. / 01.02.2019 / PubMed / Full text

MS4A1

• Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text

MS4A4A

• Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text

MS4A6A

• Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text

MSH3

• RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text

MSH5

• Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease. / 11.2015 / PubMed / Full text

MSN

• The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease. / 01.2017 / PubMed / Full text

MSR1

• Role of TGFβ signaling in the pathogenesis of Alzheimer's disease. / 2015 / PubMed / Full text

MSRA

• Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis. / 02.2019 / PubMed / Full text

MT1B

• Pharmacological advantages of melatonin in immunosenescence by improving activity of T lymphocytes. / 07.2016 / PubMed / Full text

MT1M

• A novel strain of Lactobacillus mucosae isolated from a Gaotian villager improves in vitro and in vivo antioxidant as well as biological properties in D-galactose-induced aging mice. / 02.2016 / PubMed / Full text

MT3

• Age-related changes of metallothionein 1/2 and metallothionein 3 expression in rat brain. / 01.2017 / PubMed / Full text

MTBP

• Multiomics Approach to Novel Therapeutic Targets for Cancer and Aging-Related Diseases: Role of Sld7 in Yeast Aging Network. / 02.2017 / PubMed / Full text

MTCH2

• The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study. / 05.2013 / PubMed / Full text

MTHFD2

• A multidimensional systems biology analysis of cellular senescence in aging and disease. / 07.04.2020 / PubMed / Full text

MTNR1A

• Influence of melatonin receptor 1A gene polymorphisms on seasonal reproduction in Sarda ewes with different body condition scores and ages. / 10.2014 / PubMed / Full text

MTTP

• Active vitamin D supplementation alleviates initiation and progression of nonalcoholic fatty liver disease by repressing the p53 pathway. / 15.01.2020 / PubMed / Full text

MUC7

• Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model. / 24.09.2019 / PubMed / Full text

MUL1

• Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models. / 28.05.2019 / PubMed / Full text

MUTYH

• Cholangiocyte senescence caused by lysophosphatidylcholine as a potential implication in carcinogenesis. / 09.2015 / PubMed / Full text

MVP

• Reexamining the minimum viable population concept for long-lived species. / 06.2013 / PubMed / Full text

MYBBP1A

• The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging. / 12.2016 / PubMed / Full text

MYBPC1

• Myosin Binding Protein-C Slow Phosphorylation is Altered in Duchenne Dystrophy and Arthrogryposis Myopathy in Fast-Twitch Skeletal Muscles. / 19.08.2015 / PubMed / Full text

MYCN

• Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells. / 2020 / PubMed / Full text

MYCNOS

• Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis. / 26.01.2017 / PubMed / Full text

MYH10

• Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

MYH9

• Estimated glomerular filtration rate (eGFR), 25(OH) D3, chronic kidney disease (CKD), the MYH9 (myosin heavy chain 9) gene in old and very elderly people. / 08.2015 / PubMed / Full text

MYLPF

• Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. / 15.05.2019 / PubMed / Full text

MYNN

• Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text

MYO18B

• A common variant in myosin-18B contributes to mathematical abilities in children with dyslexia and intraparietal sulcus variability in adults. / 19.02.2013 / PubMed / Full text

MYO1F

• A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. / 2019 / PubMed / Full text

MYO5B

• Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. / 12.2017 / PubMed / Full text

MYOC

• Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells. / 28.12.2018 / PubMed / Full text

MYOF

• Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text

MYOG

• Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice. / 08.2016 / PubMed / Full text

MYSM1

• MYSM1 Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan. / 11.2020 / PubMed / Full text

MYT1

• ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the MYT1-Egln3-Sirt1 Axis. / 01.10.2020 / PubMed / Full text

NACA

• Age and Sex Are Strongly Correlated to the Rate and Type of Mountain Injuries Requiring Search and Rescue Missions. / 12.2019 / PubMed / Full text

NAF1

• Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants. / 12.2019 / PubMed / Full text

NAIP

• Protective effect of xanthohumol against age-related brain damage. / 11.2017 / PubMed / Full text

NBPF6

• Genomewide Association Scan of a Mortality Associated Endophenotype for a Long and Healthy Life in the Long Life Family Study. / 01.10.2017 / PubMed / Full text

NCAPD2

• KDM3A and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization. / 22.11.2019 / PubMed / Full text

NCAPG2

• KDM3A and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization. / 22.11.2019 / PubMed / Full text

NCK2

• Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

NCOR2

• DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

NCSTN

• The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text

NDN

• The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging. / 2018 / PubMed / Full text

NDP

• Association between Cognitive Status before Surgery and Outcomes in Elderly Patients with Hip Fracture in a Dedicated Orthogeriatric Care Pathway. / 2017 / PubMed / Full text

NDUFA8

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

NDUFA9

• Preservation of skeletal muscle mitochondrial content in older adults: relationship between mitochondria, fibre type and high-intensity exercise training. / 01.06.2017 / PubMed / Full text

NDUFAB1

• Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

NDUFS4

• Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian longevity. / 07.2020 / PubMed / Full text

NDUFS7

• Nod-like receptor pyrin containing 3 (NLRP3) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation. / 01.2016 / PubMed / Full text

NDUFS8

• Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity. / 01.10.2020 / PubMed / Full text

NDUFV1

• Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. / 04.2014 / PubMed / Full text

NEBL

• Isolation and characterization of the human immature osteoblast culture system from the alveolar bones of aged donors for bone regeneration therapy. / 12.2014 / PubMed / Full text

NEDD4L

• DP1 Activation Reverses Age-Related Hypertension Via NEDD4L-Mediated T-Bet Degradation in T Cells. / 25.02.2020 / PubMed / Full text

NEGR1

• The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study. / 05.2013 / PubMed / Full text

NEIL3

• Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin. / 2019 / PubMed / Full text

NEK9

• Effect of sex, age and genetics on crossover interference in cattle. / 28.11.2016 / PubMed / Full text

NELL1

• Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. / 04.2018 / PubMed / Full text

NEU1

• Sialylation regulates myofibroblast differentiation of human skin fibroblasts. / 18.04.2017 / PubMed / Full text

NF2

• Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression. / 21.11.2016 / PubMed / Full text

NFIA

• Cell-type-specific expression of NFIX in the developing and adult cerebellum. / 07.2017 / PubMed / Full text

NFIL3

• [Identification of single nucleotide polymorphisms in centenarians]. / 05-06.2016 / PubMed / Full text

NFIX

• Cell-type-specific expression of NFIX in the developing and adult cerebellum. / 07.2017 / PubMed / Full text

NFKB2

• Partial sleep deprivation activates the DNA damage response (DDR) and the senescence-associated secretory phenotype (SASP) in aged adult humans. / 01.2016 / PubMed / Full text

NFKBIA

• Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging. / 28.12.2016 / PubMed / Full text

NHP2

• Pseudouridylation defect due to [i]DKC1[/i] and [i]NOP10[/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. / 30.06.2020 / PubMed / Full text

NIN

• Increased macromolecular damage due to oxidative stress in the neocortex and hippocampus of WNIN/Ob, a novel rat model of premature aging. / 06.06.2014 / PubMed / Full text

NIPA2

• A multidimensional systems biology analysis of cellular senescence in aging and disease. / 07.04.2020 / PubMed / Full text

NKAP

• NKAP Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors. / 2019 / PubMed / Full text

NKIRAS2

• Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

NKX2-1

• Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. / 03.2015 / PubMed / Full text

NKX2-5

• Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart. / 07.01.2019 / PubMed / Full text

NKX6-1

• The dynamic methylome of islets in health and disease. / 09.2019 / PubMed / Full text

NLRP5

• Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa. / 02.2016 / PubMed / Full text

NLRP6

• LRP6 targeting suppresses gastric tumorigenesis via P14 -Mdm2-P53-dependent cellular senescence. / 19.12.2017 / PubMed / Full text

NMI

• Age-Dependent Control of Shoulder Muscles During a Reach-and-Lift Task. / 10.12.2019 / PubMed / Full text

NMNAT3

• Restoration of Mitochondrial NAD Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells. / 12.2016 / PubMed / Full text

NMRK2

• Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training. / 2018 / PubMed / Full text

NMU

• [Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules]. / 2019 / PubMed / Full text

NMUR1

• [Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules]. / 2019 / PubMed / Full text

NMUR2

• [Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules]. / 2019 / PubMed / Full text

NOBOX

• Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. / 18.10.2017 / PubMed / Full text

NOD2

• Molecular modeling in the age of clinical genomics, the enterprise of the next generation. / 03.2017 / PubMed / Full text

NOL12

• NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging. / 15.06.2019 / PubMed / Full text

NOLC1

• Enhanced NOLC1 promotes cell senescence and represses hepatocellular carcinoma cell proliferation by disturbing the organization of nucleolus. / 08.2017 / PubMed / Full text

NOTCH4

• Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH. / 11.2020 / PubMed / Full text

NPB

• The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle. / 2019 / PubMed / Full text

NPBWR1

• Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

NPFFR2

• Genome-wide association study for longevity with whole-genome sequencing in 3 cattle breeds. / 09.2016 / PubMed / Full text

NPPB

• Chloride channels are involved in sperm motility and are downregulated in spermatozoa from patients with asthenozoospermia. / 07-08.2017 / PubMed / Full text

NPRL2

• KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text

NPRL3

• KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text

NPSR1

• Variants of asthma and chronic obstructive pulmonary disease genes and lung function decline in aging. / 07.2014 / PubMed / Full text

NPY2R

• Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. / 2015 / PubMed / Full text

NQO2

• The ontogeny and population variability of human hepatic dihydronicotinamide riboside:quinone oxidoreductase (NQO2). / 08.2017 / PubMed / Full text

NR1D1

• Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells. / 02.2020 / PubMed / Full text

NR1H3

• Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text

NR2C2

• Minireview: Pathophysiological roles of the TR4 nuclear receptor: lessons learned from mice lacking TR4. / 06.2014 / PubMed / Full text

NR2F2

• Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array. / 01.10.2020 / PubMed / Full text

NR5A2

• Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. / 12.2017 / PubMed / Full text

NRARP

• Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing NRARP. / 10.11.2018 / PubMed / Full text

NRSN2

• Down-Regulated NRSN2 Promotes Cell Proliferation and Survival Through PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma. / 10.2015 / PubMed / Full text

NRXN2

• Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex. / 01.01.2017 / PubMed / Full text

NSD1

• Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1. / 14.08.2019 / PubMed / Full text

NSF

• Effects of air pollution on children from a socioecological perspective. / 15.11.2019 / PubMed / Full text

NSMCE2

• NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity. / 03.11.2015 / PubMed / Full text

NSUN2

• RNA methyltransferase NSUN2 promotes stress-induced HUVEC senescence. / 12.04.2016 / PubMed / Full text

NSUN5

• Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan. / 30.01.2015 / PubMed / Full text

NT5E

• The NT5E gene variant strongly affects the degradation rate of inosine 5'-monophosphate under postmortem conditions in Japanese Black beef. / 12.2019 / PubMed / Full text

NTHL1

• Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals. / 04.2020 / PubMed / Full text

NTM

• Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections. / 01.11.2016 / PubMed / Full text

NTN4

• EGF/EGFR upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence. / 04.12.2018 / PubMed / Full text

NTNG2

• Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. / 03.2020 / PubMed / Full text

NUBP2

• Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. / 10.2016 / PubMed / Full text

NUCB2

• Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise Killifish. / 31.12.2019 / PubMed / Full text

NUDT12

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

NUPR1

• NUPR1 maintains autolysosomal efflux by activating SNAP25 transcription in cancer cells. / 2018 / PubMed / Full text

NUSAP1

• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

NVL

• [The effectiveness of non-invasive lung ventilation in lateral amyotrophic sclerosis]. / 2014 / PubMed

NXF1

• WRN modulates translation by influencing nuclear mRNA export in HeLa cancer cells. / 14.10.2020 / PubMed / Full text

OAS1

• Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array. / 01.10.2020 / PubMed / Full text

OASL

• Effect of age on the pathogenesis of DHV-1 in Pekin ducks and on the innate immune responses of ducks to infection. / 05.2014 / PubMed / Full text

OAZ1

• Identification of reference genes for RT-qPCR data normalisation in aging studies. / 27.09.2019 / PubMed / Full text

OCLN

• Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats. / 17.07.2019 / PubMed / Full text

OCRL

• Decreased urinary excretion of the ectodomain form of megalin (A-megalin) in children with OCRL gene mutations. / 04.2017 / PubMed / Full text

ODC1

• The curious case of polyamines: spermidine drives reversal of B cell senescence. / 03.2020 / PubMed / Full text

OGDH

• An integrated metabolomic and gene expression analysis identifies heat and calcium metabolic networks underlying postharvest sweet cherry fruit senescence. / 12.2019 / PubMed / Full text

OGFOD1

• 2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process. / 10.2015 / PubMed / Full text

OLFML3

• Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text

OMA1

• 'Mitotherapy' for Heart Failure. / 04.2016 / PubMed / Full text

ONECUT1

• Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects. / 09.2020 / PubMed / Full text

OOEP

• Maternal gene [i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes. / 18.11.2018 / PubMed / Full text

OPLAH

• An integrated metabolomic and gene expression analysis identifies heat and calcium metabolic networks underlying postharvest sweet cherry fruit senescence. / 12.2019 / PubMed / Full text

OPRD1

• A commonly carried genetic variant in the delta opioid receptor gene, OPRD1, is associated with smaller regional brain volumes: replication in elderly and young populations. / 04.2014 / PubMed / Full text

OR2AG1

• The activation of OR51E1 causes growth suppression of human prostate cancer cells. / 26.07.2016 / PubMed / Full text

OR51E1

• The activation of OR51E1 causes growth suppression of human prostate cancer cells. / 26.07.2016 / PubMed / Full text

OR51E2

• The activation of OR51E1 causes growth suppression of human prostate cancer cells. / 26.07.2016 / PubMed / Full text

ORC1

• The hyperornithinemia-hyperammonemia-homocitrullinuria syndrome. / 11.03.2015 / PubMed / Full text

ORMDL3

• Differentially methylated gene patterns between age-matched sarcopenic and non-sarcopenic women. / 12.2019 / PubMed / Full text

OSCAR

• Awareness tool for safe and responsible driving (OSCAR): a potential educational intervention for increasing interest, openness and knowledge about the abilities required and compensatory strategies among older drivers. / 2015 / PubMed / Full text

OSGEP

• Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text

OTUD7A

• A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. / 07.2013 / PubMed / Full text

OXT

• Medial amygdala lesions modify aggressive behavior and immediate early gene expression in oxytocin and vasopressin neurons during intermale exposure. / 15.05.2013 / PubMed / Full text

P2RX3

• Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array. / 01.10.2020 / PubMed / Full text

P2RX4

• A rare functional haplotype of the P2RX4 and P2RX7 genes leads to loss of innate phagocytosis and confers increased risk of age-related macular degeneration. / 04.2013 / PubMed / Full text

P2RY10

• Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury. / 12.06.2019 / PubMed / Full text

P4HA2

• Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients. / 03.09.2019 / PubMed / Full text

P4HA3

• Age-associated genes in human mammary gland drive human breast cancer progression. / 15.06.2020 / PubMed / Full text

PABPC1

• Comprehensive Analysis of Interaction Networks of Telomerase Reverse Transcriptase with Multiple Bioinformatic Approaches: Deep Mining the Potential Functions of Telomere and Telomerase. / 08.2017 / PubMed / Full text

PACSIN1

• GluN3A promotes dendritic spine pruning and destabilization during postnatal development. / 09.07.2014 / PubMed / Full text

PAFAH2

• Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs. / 03.2019 / PubMed / Full text

PAK2

• Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts. / 11-12.2015 / PubMed / Full text

PALM

• Signatures of malaria vaccine efficacy in ageing murine immune memory. / 05.2014 / PubMed / Full text

PAPSS1

• Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text

PARN

• CD8 T-cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with PARN and DKC1 mutations. / 09.2020 / PubMed / Full text

PARP2

• Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. / 2017 / PubMed / Full text

PATE1

• Aged men share the sperm protein PATE1 defect with young asthenozoospermia patients. / 04.2015 / PubMed / Full text

PAX1

• Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text

PAX4

• Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. / 03.2015 / PubMed / Full text

PAX7

• Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits. / 10.2018 / PubMed / Full text

PAX8

• Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging. / 13.09.2019 / PubMed / Full text

PBX4

• Differentially methylated gene patterns between age-matched sarcopenic and non-sarcopenic women. / 12.2019 / PubMed / Full text

PCBP2

• RNA-binding Protein PCBP2 Regulates p73 Expression and p73-dependent Antioxidant Defense. / 29.04.2016 / PubMed / Full text

PCCA

• Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism. / 03.2018 / PubMed / Full text

PCCB

• Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism. / 03.2018 / PubMed / Full text

PCDH9

• A reverse genetics cell-based evaluation of genes linked to healthy human tissue age. / 01.2017 / PubMed / Full text

PCDHGA3

• DNA methylation associated with healthy aging of elderly twins. / 12.2018 / PubMed / Full text

PCGF2

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text

PCGF3

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text

PCGF5

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text

PCK1

• PCK1 is negatively regulated by bta-miR-26a, and a single-nucleotide polymorphism in the 3' untranslated region is involved in semen quality and longevity of Holstein bulls. / 03.2016 / PubMed / Full text

PCMTD1

• Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

PCP4

• Specific age-related molecular alterations in the cerebellum of Down syndrome mouse models. / 01.09.2016 / PubMed / Full text

PDE11A

• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDE1B

• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDE3B

• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDE4A

• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDE7A

• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDE7B

• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDE8A

• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDE8B

• Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text

PDGFRA

• GBM-associated mutations and altered protein expression are more common in young patients. / 25.10.2016 / PubMed / Full text

PDP1

• Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training. / 01.07.2016 / PubMed / Full text

PDP2

• Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training. / 01.07.2016 / PubMed / Full text

PEBP1

• [i]Drosophila[/i] PEBP1 inhibits intestinal stem cell aging via suppression of ERK pathway. / 06.04.2018 / PubMed / Full text

PER3

• Effects of PER3 clock gene polymorphisms on aging-related changes of the cerebral cortex. / 03.2018 / PubMed / Full text

PEX1

• Transcription factor PEX1 modulates extracellular matrix turnover through regulation of MMP-9 expression. / 02.2017 / PubMed / Full text

PEX19

• A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells. / 02.2020 / PubMed / Full text

PEX5

• Aging lowers PEX5 levels in cortical neurons in male and female mouse brains. / 09.2020 / PubMed / Full text

PF4V1

• Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. / 05.2019 / PubMed / Full text

PFKL

• Developmental changes in hepatic glucose metabolism in a newborn piglet model: A comparative analysis for suckling period and early weaning period. / 19.02.2016 / PubMed / Full text

PGAP1

• Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text

PGK2

• Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice. / 01.2020 / PubMed / Full text

PGLS

• 547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates. / 28.11.2019 / PubMed / Full text

PGLYRP1

• PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan. / 16.01.2014 / PubMed / Full text

PGLYRP2

• Innate immune response to LPS in airway epithelium is dependent on chronological age and antecedent exposures. / 11.2013 / PubMed / Full text

PGM1

• Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. / 15.05.2019 / PubMed / Full text

PHAX

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

PHF19

• A reverse genetics cell-based evaluation of genes linked to healthy human tissue age. / 01.2017 / PubMed / Full text

PHF6

• miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. / 03.01.2015 / PubMed / Full text

PHGDH

• Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase. / 01.08.2019 / PubMed / Full text

PHLPP1

• Defects in the CAPN1 Gene Result in Alterations in Cerebellar Development and Cerebellar Ataxia in Mice and Humans. / 28.06.2016 / PubMed / Full text

PHOSPHO1

• Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing. / 12.2015 / PubMed / Full text

PI4KA

• Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease. / 10.2015 / PubMed / Full text

PIAS1

• Age-Dependent and -Independent Effects of Perivascular Adipose Tissue and Its Paracrine Activities during Neointima Formation. / 31.12.2019 / PubMed / Full text

PICK1

• Development- and age-related alterations in the expression of AMPA receptor subunit GluR2 and its trafficking proteins in the hippocampus of male mouse brain. / 06.2015 / PubMed / Full text

PIGR

• Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

PIK3C2A

• Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text

PIK3C2B

• In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text

PIK3C3

• Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo. / 03.08.2015 / PubMed / Full text

PIK3CB

• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

PIK3R1

• Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. / 08.10.2018 / PubMed / Full text

PIK3R3

• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

PIM1

• PIM1-catalyzed CBX8 phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast. / 27.06.2018 / PubMed / Full text

PIP5K1C

• [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text

PIPOX

• Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma. / 21.12.2016 / PubMed / Full text

PKD1

• The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response. / 16.03.2018 / PubMed / Full text

PKHD1L1

• [Role of PLAT, PKHD1L1, STK38L and TEAD1 genes Alu-polymorphism for longevity]. / 2016 / PubMed

PKLR

• Developmental changes in hepatic glucose metabolism in a newborn piglet model: A comparative analysis for suckling period and early weaning period. / 19.02.2016 / PubMed / Full text

PKNOX1

• The effects of environmental stressors on candidate aging associated genes. / 08.2020 / PubMed / Full text

PLA2G4A

• Coordination of gene expression of arachidonic and docosahexaenoic acid cascade enzymes during human brain development and aging. / 2014 / PubMed / Full text

PLA2G4B

• Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism. / 04.2020 / PubMed / Full text

PLA2G7

• Elevated PLA2G7 gene promoter methylation as a gender-specific marker of aging increases the risk of coronary heart disease in females. / 2013 / PubMed / Full text

PLAGL1

• Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis. / 12.2015 / PubMed / Full text

PLAT

• [Role of PLAT, PKHD1L1, STK38L and TEAD1 genes Alu-polymorphism for longevity]. / 2016 / PubMed

PLCB1

• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

PLCD1

• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

PLCG2

• A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. / 08.2019 / PubMed / Full text

PLEC

• Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model. / 07.2014 / PubMed / Full text

PLEKHA6

• In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text

PLEKHO1

• Increased PLEKHO1 within osteoblasts suppresses Smad-dependent BMP signaling to inhibit bone formation during aging. / 04.2017 / PubMed / Full text

PLIN1

• Determination of the Mechanisms that Cause Sarcopenia through cDNA Microarray. / 2017 / PubMed / Full text

PLK2

• Age- and brain region-dependent α-synuclein oligomerization is attributed to alterations in intrinsic enzymes regulating α-synuclein phosphorylation in aging monkey brains. / 23.02.2016 / PubMed / Full text

PLP1

• Age-related changes in a patient with Pelizaeus-Merzbacher disease determined by repeated 1H-magnetic resonance spectroscopy. / 02.2014 / PubMed / Full text

PLTP

• PLTP deficiency impairs learning and memory capabilities partially due to alteration of amyloid-β metabolism in old mice. / 2014 / PubMed / Full text

PLXNA4

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

PMM2

• Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model. / 01.05.2016 / PubMed / Full text

PMS1

• RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text

PNPLA6

• Delayed Induction of Human NTE (PNPLA6) Rescues Neurodegeneration and Mobility Defects of Drosophila swiss cheese (sws) Mutants. / 2015 / PubMed / Full text

PODXL

• Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. / 01.09.2017 / PubMed / Full text

POLDIP2

• Essential role of POLDIP2 in Tau aggregation and neurotoxicity via autophagy/proteasome inhibition. / 26.06.2015 / PubMed / Full text

POLL

• Temporal trends in loss of life expectancy after a cancer diagnosis among the Australian population. / 04.2020 / PubMed / Full text

POLN

• Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance. / 06.2017 / PubMed / Full text

POLR3A

• Nucleolar disruption, activation of P53 and premature senescence in POLR3A-mutated Wiedemann-Rautenstrauch syndrome fibroblasts. / 12.2020 / PubMed / Full text

POU2F1

• Methyl CpG level at distal part of heat-shock protein promoter HSP70 exhibits epigenetic memory for heat stress by modulating recruitment of POU2F1-associated nucleosome-remodeling deacetylase (NuRD) complex. / 05.2017 / PubMed / Full text

POU3F2

• POU3F2 participates in cognitive function and adult hippocampal neurogenesis via mammalian-characteristic amino acid repeats. / 02.2018 / PubMed / Full text

POU4F3

• In Vivo Interplay between p27 , GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice. / 11.04.2017 / PubMed / Full text

PPA2

• Characterization of long living yeast deletion mutants that lack mitochondrial metabolism genes DSS1, PPA2 and AFG3. / 20.07.2019 / PubMed / Full text

PPARA

• [Genotype and allele frequencies of UCP and PPAR gene families in residents of besieged Leningrad and in the control group]. / 2014 / PubMed

PPCDC

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

PPFIA1

• Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text

PPM1A

• The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1. / 03.08.2019 / PubMed / Full text

PPM1B

• PPM1B depletion induces premature senescence in human IMR-90 fibroblasts. / 06.2014 / PubMed / Full text

PPP1R12B

• BDA-410 Treatment Reduces Body Weight and Fat Content by Enhancing Lipolysis in Sedentary Senescent Mice. / 01.08.2017 / PubMed / Full text

PPP1R15B

• In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text

PPP1R1B

• Effects of PPP1R1B (DARPP-32) Polymorphism on Feedback-Related Brain Potentials Across the Life Span. / 2013 / PubMed / Full text

PPP1R3C

• Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text

PPP2R1A

• Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text

PPP2R2B

• Germline genetics of the p53 pathway affect longevity in a gender specific manner. / 2014 / PubMed / Full text

PPP2R3C

• The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver. / 04.2019 / PubMed / Full text

PPT1

• Neuroprotection and lifespan extension in Ppt1(-/-) mice by NtBuHA: therapeutic implications for INCL. / 11.2013 / PubMed / Full text

PRDM1

• Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients. / 17.01.2019 / PubMed / Full text

PRDM8

• PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation. / 20.08.2020 / PubMed / Full text

PRDX2

• Regulation of PRDX1 peroxidase activity by Pin1. / 15.03.2013 / PubMed / Full text

PRDX5

• The antioxidant icariin protects porcine oocytes from age-related damage in vitro. / 12.05.2020 / PubMed / Full text

PRG2

• Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells. / 2016 / PubMed / Full text

PRKAA1

• Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

PRKACA

• Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼. / 11.2020 / PubMed / Full text

PRKCB

• MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells. / 18.03.2019 / PubMed / Full text

PRKCD

• Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text

PRKCH

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

PRKDC

• DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis. / 29.08.2019 / PubMed / Full text

PRKN

• PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. / 03.2019 / PubMed / Full text

PRLR

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

PRM1

• Cytological and molecular aspects of the ageing sperm. / 01.02.2019 / PubMed / Full text

PRM2

• Cytological and molecular aspects of the ageing sperm. / 01.02.2019 / PubMed / Full text

PRODH

• Proline dehydrogenase promotes senescence through the generation of reactive oxygen species. / 15.04.2017 / PubMed / Full text

PRR9

• Circadian control of [i]ORE1[/i] by PRR9 positively regulates leaf senescence in [i]Arabidopsis[/i]. / 14.08.2018 / PubMed / Full text

PRRC2A

• Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text

PRRX1

• A SIRT1-centered circuitry regulates breast cancer stemness and metastasis. / 12.2018 / PubMed / Full text

PRSS16

• The complex genetics of gait speed: genome-wide meta-analysis approach. / 10.01.2017 / PubMed / Full text

PSAP

• Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. / 08.2018 / PubMed / Full text

PSMA7

• Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence. / 2017 / PubMed / Full text

PSMB10

• Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome. / 06.2017 / PubMed / Full text

PSMB5

• Ameliorating replicative senescence of human bone marrow stromal cells by PSMB5 overexpression. / 24.01.2014 / PubMed / Full text

PSMB9

• Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome. / 06.2017 / PubMed / Full text

PSMD11

• The effect and mechanism of 19S proteasome PSMD11/Rpn6 subunit in D-Galactose induced mimetic aging models. / 01.09.2020 / PubMed / Full text

PSMD13

• Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

PSMD14

• Upregulation of deubiquitinase PSMD14 in lung adenocarcinoma (LUAD) and its prognostic significance. / 2020 / PubMed / Full text

PSMG1

• Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. / 03.2018 / PubMed / Full text

PSTK

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

PTCH1

• Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text

PTGDR

• Does prostaglandin D2 hold the cure to male pattern baldness? / 04.2014 / PubMed / Full text

PTGDS

• Does prostaglandin D2 hold the cure to male pattern baldness? / 04.2014 / PubMed / Full text

PTGER2

• Molecular cloning and expression analysis of prostaglandin E receptor 2 gene in cashmere goat (Capra hircus) skin during hair follicle development. / 03.04.2014 / PubMed / Full text

PTH2R

• Variation in the [[PTH2R]] gene is associated with age-related degenerative changes in the lumbar spine. / 01.2015 / PubMed / Full text

PTHLH

• Variation in the [[PTH2R]] gene is associated with age-related degenerative changes in the lumbar spine. / 01.2015 / PubMed / Full text

PTK2

• PTK2 rs7460 and rs7843014 polymorphisms and exceptional longevity: a functional replication study. / 10.2014 / PubMed / Full text

PTP4A3

• Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease. / 05.2020 / PubMed / Full text

PTPN7

• DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers. / 07.2017 / PubMed / Full text

PTPRC

• Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text

PTPRD

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

PTPRR

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

PTPRT

• The complex genetics of gait speed: genome-wide meta-analysis approach. / 10.01.2017 / PubMed / Full text

PUM1

• Identification of reference genes for RT-qPCR data normalisation in aging studies. / 27.09.2019 / PubMed / Full text

PXN

• pxn-1 and pxn-2 May Interact Negatively during Neuronal Development and Aging in C. elegans. / 08.2015 / PubMed / Full text

QRFPR

• Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text

RAB10

• Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2 mice. / 10.12.2020 / PubMed / Full text

RAB1B

• Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

RAB27A

• Reduced expression level of the cyclic adenosine monophosphate response element-binding protein contributes to lung aging. / 01.2014 / PubMed / Full text

RAC3

• RAC3 more than a nuclear receptor coactivator: a key inhibitor of senescence that is downregulated in aging. / 15.10.2015 / PubMed / Full text

RAD21

• Suppression of RAD21 Induces Senescence of MDA-MB-231 Human Breast Cancer Cells Through RB1 Pathway Activation Via c-Myc Downregulation. / 06.2016 / PubMed / Full text

RAD23A

• Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

RAD51C

• Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population. / 06.2019 / PubMed / Full text

RAD9A

• Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

RAI1

• DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

RAMP1

• Depressed perivascular sensory innervation of mouse mesenteric arteries with advanced age. / 15.04.2016 / PubMed / Full text

RAMP2

• Vascular endothelial adrenomedullin-RAMP2 system is essential for vascular integrity and organ homeostasis. / 19.02.2013 / PubMed / Full text

RAPGEF2

• Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans. / 12.2017 / PubMed / Full text

RARB

• Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. / 12.2019 / PubMed / Full text

RASEF

• Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma. / 07.2014 / PubMed / Full text

RASGEF1A

• Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text

RASGRF2

• A single nucleotide polymorphism associated with reduced alcohol intake in the RASGRF2 gene predicts larger cortical volumes but faster longitudinal ventricular expansion in the elderly. / 2013 / PubMed / Full text

RB1CC1

• Tumor-suppressive functions of 15-Lipoxygenase-2 and RB1CC1 in prostate cancer. / 2014 / PubMed / Full text

RBBP4

• Retinoblastoma-binding Protein 4-regulated Classical Nuclear Transport Is Involved in Cellular Senescence. / 04.12.2015 / PubMed / Full text

RBFOX1

• Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology. / 05.08.2020 / PubMed / Full text

RBL1

• Deregulation of hsa-miR-20b expression in TNF-α-induced premature senescence of human pulmonary microvascular endothelial cells. / 11.2017 / PubMed / Full text

RBM25

• HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif. / 29.04.2019 / PubMed / Full text

RBM3

• Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. / 2018 / PubMed / Full text

RBM34

• The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort. / 2020 / PubMed / Full text

RBM38

• Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating PTEN. / 15.03.2018 / PubMed / Full text

RBM6

• Bayesian association scan reveals loci associated with human lifespan and linked biomarkers. / 27.07.2017 / PubMed / Full text

RBMXL1

• Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text

RBP1

• The SR proteins SF2 and RBP1 regulate triglyceride storage in the fat body of Drosophila. / 27.08.2019 / PubMed / Full text

RC3H2

• The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text

RDX

• Toxicity of the conventional energetics TNT and RDX relative to new insensitive munitions constituents DNAN and NTO in Rana pipiens tadpoles. / 04.2015 / PubMed / Full text

REEP4

• Chromosome Missegregation in Single Human Oocytes Is Related to the Age and Gene Expression Profile. / 12.03.2020 / PubMed / Full text

REL

• Impact of loss of NF-κB1, NF-κB2 or c-REL on SLE-like autoimmune disease and lymphadenopathy in Fas(lpr/lpr) mutant mice. / 01.2016 / PubMed / Full text

RELB

• New control of the senescence barrier in breast cancer. / 2020 / PubMed / Full text

REV1

• REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. / 17.11.2020 / PubMed / Full text

RFWD3

• Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text

RGL1

• Arabidopsis WRKY45 Interacts with the DELLA Protein RGL1 to Positively Regulate Age-Triggered Leaf Senescence. / 12.09.2017 / PubMed / Full text

RGS10

• Age-related changes in regulator of G-protein signaling (RGS)-10 expression in peripheral and central immune cells may influence the risk for age-related degeneration. / 05.2015 / PubMed / Full text

RGS14

• Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. / 08.2018 / PubMed / Full text

RGS3

• The roles of ribosomal protein S19 C-terminus in a shortened neutrophil lifespan through delta lactoferrin. / 09.2015 / PubMed / Full text

RHCG

• Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma. / 06.06.2019 / PubMed / Full text

RHD

• Suppression and narrative time shifts in adults with right-hemisphere brain damage. / 05.2013 / PubMed / Full text

RHEBL1

• Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. / 03.2018 / PubMed / Full text

RHOB

• Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes. / 13.06.2019 / PubMed / Full text

RIC3

• Genetic modifiers of cognitive maintenance among older adults. / 09.2014 / PubMed / Full text

RIF1

• 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. / 02.01.2020 / PubMed / Full text

RIMS2

• Age-related gene and miRNA expression changes in airways of healthy individuals. / 06.03.2019 / PubMed / Full text

RIN3

• Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text

RNASEL

• Age-related methylation profiles of equine blood leukocytes in the RNASEL locus. / 08.2016 / PubMed / Full text

RNF10

• Reduced RING finger protein 10 expression in macrophages is associated with aging-related inflammation. / 28.11.2020 / PubMed / Full text

RNF111

• Global-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo Modifiers. / 2016 / PubMed / Full text

RNF13

• The effects of environmental stressors on candidate aging associated genes. / 08.2020 / PubMed / Full text

RNF144A

• Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. / 09.2019 / PubMed / Full text

RORB

• Effects of circadian clock genes and environmental factors on cognitive aging in old adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text

ROS1

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

RPA1

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

RPA2

• Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

RPL13

• Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text

RPL18

• Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts. / 2015 / PubMed / Full text

RPL30

• Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text

RPL31

• Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text

RPL36

• Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

RPL37

• Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text

RPL4

• Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

RPS11

• Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts. / 2015 / PubMed / Full text

RPS19BP1

• Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence. / 10.2020 / PubMed / Full text

RPS6KA1

• Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry. / 02.2015 / PubMed / Full text

RPS6KB1

• Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text

RPS7

• Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts. / 2015 / PubMed / Full text

RRAD

• Pan-senescence transcriptome analysis identified RRAD as a marker and negative regulator of cellular senescence. / 01.2019 / PubMed / Full text

RRM2B

• Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs. / 15.07.2018 / PubMed / Full text

RS1

• Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h-/- mouse. / 06.2014 / PubMed / Full text

RSAD2

• Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. / 02.08.2017 / PubMed / Full text

RSF1

• The SR proteins SF2 and RBP1 regulate triglyceride storage in the fat body of Drosophila. / 27.08.2019 / PubMed / Full text

RSL1D1

• Ribosomal L1 domain and lysine-rich region are essential for CSIG/ RSL1D1 to regulate proliferation and senescence. / 15.01.2016 / PubMed / Full text

RTN3

• Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. / 09.2016 / PubMed / Full text

RTN4

• Cell fate regulation by reticulon-4 in human prostate cancers. / 07.2019 / PubMed / Full text

RUNX3

• circLARP4 induces cellular senescence through regulating miR-761/RUNX3/p53/p21 signaling in hepatocellular carcinoma. / 02.2019 / PubMed / Full text

RUVBL2

• Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue. / 09.2015 / PubMed / Full text

RXFP1

• Sex- and age-specific differences in relaxin family peptide receptor expression within the hippocampus and amygdala in rats. / 22.01.2015 / PubMed / Full text

RXFP3

• The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage. / 03.12.2019 / PubMed / Full text

RXRA

• The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling. / 12.2018 / PubMed / Full text

RYR3

• Association of the RYR3 gene polymorphisms with atherosclerosis in elderly Japanese population. / 14.01.2014 / PubMed / Full text

S100A10

• Age-related and depot-specific changes in white adipose tissue of growth hormone receptor-null mice. / 01.2014 / PubMed / Full text

S100A13

• S100A13 promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α. / 23.01.2019 / PubMed / Full text

S100A7

• The secreted protein S100A7 (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulators. / 2014 / PubMed / Full text

S100P

• Cancer-associated S100P protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance. / 19.04.2016 / PubMed / Full text

SAA2

• Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells. / 2018 / PubMed / Full text

SACM1L

• Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text

SAMD10

• Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

SAMD12

• Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom. / 05.2018 / PubMed / Full text

SAMHD1

• Gut microbiota lipopolysaccharide accelerates inflamm-aging in mice. / 16.01.2016 / PubMed / Full text

SARM1

• Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy. / 03.10.2017 / PubMed / Full text

SAT1

• Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action. / 08.2020 / PubMed / Full text

SCAMP1

• Secretory Carrier Membrane Protein (SCAMP) deficiency influences behavior of adult flies. / 2014 / PubMed / Full text

SCAMP4

• SCAMP4 enhances the senescent cell secretome. / 01.07.2018 / PubMed / Full text

SCD5

• Bovine brain region-specific stearoyl-CoA desaturase expression and fatty acid composition. / 06.2015 / PubMed / Full text

SCGB1A1

• Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. / 03.2015 / PubMed / Full text

SCGB2A2

• Sensitivity of neoplastic cells to senescence unveiled under standard cell culture conditions. / 05.2015 / PubMed

SCGB3A2

• Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. / 03.2015 / PubMed / Full text

SCN1A

• Effects of normal aging and SCN1A risk-gene expression on brain metabolites: evidence for an association between SCN1A and myo-inositol. / 02.2014 / PubMed / Full text

SCN2A

• Na 1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age. / 09.09.2019 / PubMed / Full text

SCN9A

• The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway. / 06.2018 / PubMed / Full text

SCNN1B

• Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. / 18.10.2018 / PubMed / Full text

SCO1

• Real-Time PCR Analysis of Metabolism-Related Genes in a Long-Lived Model of C. elegans. / 2020 / PubMed / Full text

SCPEP1

• Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A. / 07.2020 / PubMed / Full text

SCRIB

• Scribble is required for pregnancy-induced alveologenesis in the adult mammary gland. / 15.06.2016 / PubMed / Full text

SCX

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

SDC2

• Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. / 01.10.2017 / PubMed / Full text

SDC3

• Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. / 01.10.2017 / PubMed / Full text

SDHAF2

• Long-term prognosis of patients with pediatric pheochromocytoma. / 02.2014 / PubMed / Full text

SDHD

• Long-term prognosis of patients with pediatric pheochromocytoma. / 02.2014 / PubMed / Full text

SEC23A

• Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice. / 14.06.2016 / PubMed / Full text

SEC23B

• Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice. / 14.06.2016 / PubMed / Full text

SELENBP1

• A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity. / 01.2020 / PubMed / Full text

SELENOH

• The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text

SELENOK

• Dietary selenium deficiency and supplementation differentially modulate the expression of two ER-resident selenoproteins (selenoprotein K and selenoprotein M) in the ovaries of aged mice: Preliminary data. / 09.2020 / PubMed / Full text

SELENOP

• Analyses of Selenotranscriptomes and Selenium Concentrations in Response to Dietary Selenium Deficiency and Age Reveal Common and Distinct Patterns by Tissue and Sex in Telomere-Dysfunctional Mice. / 10.2017 / PubMed / Full text

SELENOT

• The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text

SELENOV

• The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text

SELENOW

• The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text

SELP

• Effect of age on expression of spermatogonial markers in bovine testis and isolated cells. / 07.2016 / PubMed / Full text

SEMA3A

• Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging. / 05.03.2019 / PubMed / Full text

SEMA6C

• Suppression of SEMA6C promotes preantral follicles atresia with decreased cell junctions in mice ovaries. / 04.2019 / PubMed / Full text

SENP1

• Aging-related SUMOylation pattern in the cortex and blood plasma of wild type mice. / 06.03.2018 / PubMed / Full text

SENP6

• Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses. / 10.2020 / PubMed / Full text

SENP7

• Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text

SERPINA1

• Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

SERPINB3

• SERPINB3 is associated with longer survival in transgenic mice. / 28.10.2013 / PubMed / Full text

SESN1

• Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis. / 09.2018 / PubMed / Full text

SETX

• Sen1, the homolog of human Senataxin, is critical for cell survival through regulation of redox homeostasis, mitochondrial function, and the TOR pathway in Saccharomyces cerevisiae. / 11.2016 / PubMed / Full text

SFPQ

• Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis. / 08.04.2020 / PubMed / Full text

SFRP5

• SFRP5 serves a beneficial role in arterial aging by inhibiting the proliferation, migration and inflammation of smooth muscle cells. / 11.2018 / PubMed / Full text

SFTPA1

• Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. / 03.2015 / PubMed / Full text

SGCE

• Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis. / 12.2015 / PubMed / Full text

SGPP2

• Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. / 25.11.2013 / PubMed / Full text

SGSH

• MPS-IIIA mice acquire autistic behaviours with age. / 07.2018 / PubMed / Full text

SH2B1

• The Dyslexia-susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling. / 01.03.2017 / PubMed / Full text

SH2B3

• Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. / 13.10.2017 / PubMed / Full text

SHC1

• Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence. / 01.2016 / PubMed / Full text

SHCBP1

• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

SHD

• Does self-reported hearing difficulty decrease older adults' cognitive and physical functioning? The mediating role of social isolation. / 11.2020 / PubMed / Full text

SHMT2

• Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects. / 22.05.2015 / PubMed / Full text

SHOX2

• Role of SHOX2 in the development of intervertebral disc degeneration. / 05.2017 / PubMed / Full text

SHROOM3

• A roadmap for the genetic analysis of renal aging. / 10.2015 / PubMed / Full text

SIGIRR

• Anti-Inflamm-Aging Effects of Long-Term Caloric Restriction via Overexpression of SIGIRR to Inhibit NF-κB Signaling Pathway. / 2015 / PubMed / Full text

SIK3

• Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids. / 25.09.2020 / PubMed / Full text

SIL1

• SIL1, the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology. / 10.05.2018 / PubMed / Full text

SIX1

• Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice. / 08.2016 / PubMed / Full text

SIX2

• Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function. / 10.05.2016 / PubMed / Full text

SIX4

• Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice. / 08.2016 / PubMed / Full text

SIX5

• Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice. / 08.2016 / PubMed / Full text

SKAP2

• Longevity-related molecular pathways are subject to midlife "switch" in humans. / 08.2019 / PubMed / Full text

SKI

• Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells. / 04.2019 / PubMed / Full text

SKP1

• Transcriptome profiling of postharvest strawberry fruit in response to exogenous auxin and abscisic acid. / 01.2016 / PubMed / Full text

SLAMF1

• Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy. / 2019 / PubMed / Full text

SLAMF7

• Age-related differences in neuroinflammatory responses associated with a distinct profile of regulatory markers on neonatal microglia. / 04.04.2014 / PubMed / Full text

SLC11A1

• The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text

SLC12A5

• DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers. / 07.2017 / PubMed / Full text

SLC12A8

• Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip. / 10.2019 / PubMed / Full text

SLC15A1

• Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing. / 02.2019 / PubMed / Full text

SLC15A2

• Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing. / 02.2019 / PubMed / Full text

SLC16A10

• The SLC16 gene family - structure, role and regulation in health and disease. / 04-06.2013 / PubMed / Full text

SLC16A2

• The SLC16 gene family - structure, role and regulation in health and disease. / 04-06.2013 / PubMed / Full text

SLC16A3

• The SLC16 gene family - structure, role and regulation in health and disease. / 04-06.2013 / PubMed / Full text

SLC17A3

• Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text

SLC17A4

• Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text

SLC1A5

• SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice. / 06.2019 / PubMed / Full text

SLC22A12

• ABCG2 rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population. / 17.03.2020 / PubMed / Full text

SLC22A14

• Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text

SLC22A23

• Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease. / 11.2018 / PubMed / Full text

SLC24A5

• [A question of colour]. / 01.2018 / PubMed / Full text

SLC25A15

• The hyperornithinemia-hyperammonemia-homocitrullinuria syndrome. / 11.03.2015 / PubMed / Full text

SLC27A1

• EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice. / 16.02.2017 / PubMed / Full text

SLC2A4RG

• Genome-wide association study for lactation persistency, female fertility, longevity, and lifetime profit index traits in Holstein dairy cattle. / 02.2017 / PubMed / Full text

SLC30A1

• Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text

SLC30A10

• Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text

SLC30A3

• SLC30A3 and SEP15 gene polymorphisms influence the serum concentrations of zinc and selenium in mature adults. / 09.2014 / PubMed / Full text

SLC30A5

• Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text

SLC36A4

• The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling. / 04.2017 / PubMed / Full text

SLC39A5

• Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients. / 03.09.2019 / PubMed / Full text

SLC39A6

• Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text

SLC41A1

• Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis. / 08.05.2019 / PubMed / Full text

SLC4A7

• Multivariate genomic scan implicates novel loci and haem metabolism in human ageing. / 16.07.2020 / PubMed / Full text

SLC52A2

• Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. / 01.11.2017 / PubMed / Full text

SLC52A3

• Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. / 01.11.2017 / PubMed / Full text

SLCO1B1

• The SLCO1B1 c.521T>C polymorphism is associated with dose decrease or switching during statin therapy in the Rotterdam Study. / 01.2014 / PubMed / Full text

SLCO1B3

• Paclitaxel-induced sensory peripheral neuropathy is associated with an ABCB1 single nucleotide polymorphism and older age in Japanese. / 06.2017 / PubMed / Full text

SLCO1C1

• Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging. / 12.2016 / PubMed / Full text

SLIT2

• Analysis of gene expression during aging of CGNs in culture: implication of SLIT2 and NPY in senescence. / 06.2015 / PubMed / Full text

SLPI

• Human buccal epithelium acquires microbial hyporesponsiveness at birth, a role for secretory leukocyte protease inhibitor. / 06.2015 / PubMed / Full text

SMAP

• DNA integrity-protecting and survival-promoting activity of serotonergic system in sturgeon juveniles and sazans. / 08.2017 / PubMed / Full text

SMARCA5

• The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability. / 13.07.2018 / PubMed / Full text

SMARCB1

• High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer. / 17.10.2017 / PubMed / Full text

SMARCD1

• Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells. / 12.2018 / PubMed / Full text

SMC1A

• Age-related decrease of meiotic cohesins in human oocytes. / 2014 / PubMed / Full text

SMC1B

• Age-related decrease of meiotic cohesins in human oocytes. / 2014 / PubMed / Full text

SMC2

• The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence. / 10.11.2018 / PubMed / Full text

SMC4

• The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence. / 10.11.2018 / PubMed / Full text

SMC5

• SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes. / 01.05.2017 / PubMed / Full text

SMG1

• SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress. / 12.2019 / PubMed / Full text

SMG6

• Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II). / 2016 / PubMed / Full text

SMPD3

• Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78-Loaded Extracellular Vesicles. / 10.12.2020 / PubMed / Full text

SMURF2

• Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text

SMYD2

• Collaboration of MYC and RUNX2 in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity. / 10.2019 / PubMed / Full text

SNAI2

• Reawakening of dormant estrogen-dependent human breast cancer cells by bone marrow stroma secretory senescence. / 17.08.2018 / PubMed / Full text

SNAP23

• Effects of immobilization and aerobic training on proteins related to intramuscular substrate storage and metabolism in young and older men. / 03.2016 / PubMed / Full text

SND1

• [Downregulation of SND1 Expression Accelerates Cell Senescence of Human Diploid Fibroblasts 2BS via Modulating the SASP]. / 05.2020 / PubMed / Full text

SNN

• Evolving Spiking Neural Networks for Recognition of Aged Voices. / 01.2017 / PubMed / Full text

SNRPE

• In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text

SNRPN

• Age-associated changes in gene expression of goat oocytes. / 01.09.2013 / PubMed / Full text

SNX15

• SNX15 Regulates Cell Surface Recycling of APP and Aβ Generation. / 08.2016 / PubMed / Full text

SOBP

• Lifetime increased cancer risk in mice following exposure to clinical proton beam-generated neutrons. / 01.05.2014 / PubMed / Full text

SORCS2

• Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. / 10.2016 / PubMed / Full text

SORT1

• Soluble sortilin is present in excess and positively correlates with progranulin in CSF of aging individuals. / 11.2016 / PubMed / Full text

SOS1

• Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via IRS1/GRB2/ SOS1, GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice. / 21.01.2019 / PubMed / Full text

SOX1

• The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans. / 20.11.2020 / PubMed / Full text

SOX10

• SOX10 Distinguishes Pilocytic and Pilomyxoid Astrocytomas From Ependymomas but Shows No Differences in Expression Level in Ependymomas From Infants Versus Older Children or Among Molecular Subgroups. / 04.2016 / PubMed / Full text

SOX11

• A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress. / 10.08.2017 / PubMed / Full text

SOX13

• In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text

SOX17

• SOX17 Regulates Conversion of Human Fibroblasts Into Endothelial Cells and Erythroblasts by Dedifferentiation Into CD34 Progenitor Cells. / 20.06.2017 / PubMed / Full text

SOX6

• Gene expression markers in horse articular chondrocytes: Chondrogenic differentiaton IN VITRO depends on the proliferative potential and ageing. Implication for tissue engineering of cartilage. / 02.2020 / PubMed / Full text

SP2

• Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography. / 12.2017 / PubMed / Full text

SP7

• microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia. / 06.2019 / PubMed / Full text

SP8

• Molecular control of two novel migratory paths for CGE-derived interneurons in the developing mouse brain. / 15.05.2016 / PubMed / Full text

SPAG9

• Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. / 10.2016 / PubMed / Full text

SPATS2L

• Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype. / 02.2019 / PubMed / Full text

SPG11

• [i]Malassezia[/i] and Parkinson's Disease. / 2019 / PubMed / Full text

SPG21

• Loss of Maspardin Attenuates the Growth and Maturation of Mouse Cortical Neurons. / 2016 / PubMed / Full text

SPG7

• Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration. / 21.02.2018 / PubMed / Full text

SPHK1

• Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina. / 10.2019 / PubMed / Full text

SPHK2

• Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. / 04.2019 / PubMed / Full text

SPI1

• Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text

SPO11

• "Mitotic Slippage" and Extranuclear DNA in Cancer Chemoresistance: A Focus on Telomeres. / 16.04.2020 / PubMed / Full text

SPX

• Phosphorus remobilization from rice flag leaves during grain filling: an RNA-seq study. / 01.2017 / PubMed / Full text

SREBF1

• The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators. / 29.09.2020 / PubMed / Full text

SRI

• The Role of Aging, Drug Dependence, and Hepatitis C Comorbidity in Alcoholism Cortical Compromise. / 01.05.2018 / PubMed / Full text

SRL

• Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment. / 04-06.2020 / PubMed / Full text

SRPK1

• [Age-related changes in the content of serine-arginine protein kinase 1 (SRPK1) in human dermis.] / 2017 / PubMed

SRSF1

• Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome. / 09.2018 / PubMed / Full text

SRSF10

• Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes. / 02.2015 / PubMed / Full text

SRSF2

• Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy. / 10.2016 / PubMed / Full text

SRSF3

• Alternative polyadenylation dependent function of splicing factor SRSF3 contributes to cellular senescence. / 04.03.2019 / PubMed / Full text

SSBP2

• Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

SSTR3

• Type 3 Adenylyl Cyclase and Somatostatin Receptor 3 Expression Persists in Aged Rat Neocortical and Hippocampal Neuronal Cilia. / 2016 / PubMed / Full text

SSX2

• Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability. / 02.2015 / PubMed / Full text

ST18

• [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text

STAT5B

• Reductions in serum IGF-1 during aging impair health span. / 06.2014 / PubMed / Full text

STC1

• Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

STC2

• Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2. / 05.12.2019 / PubMed / Full text

STIP1

• The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1. / 03.04.2020 / PubMed / Full text

STK11

• A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer. / 04.2017 / PubMed / Full text

STK32C

• DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

STK38L

• [Role of PLAT, PKHD1L1, STK38L and TEAD1 genes Alu-polymorphism for longevity]. / 2016 / PubMed

STOML2

• Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease. / 2017 / PubMed / Full text

STRA6

• Transport of vitamin A across blood-tissue barriers is facilitated by STRA6. / 08.2016 / PubMed / Full text

STX16

• Clinical characterization and molecular classification of 12 Korean patients with pseudohypoparathyroidism and pseudopseudohypoparathyroidism. / 10.2013 / PubMed / Full text

STX17

• Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and XIAP. / 01.10.2019 / PubMed / Full text

SUCLA2

• An integrated metabolomic and gene expression analysis identifies heat and calcium metabolic networks underlying postharvest sweet cherry fruit senescence. / 12.2019 / PubMed / Full text

SUCNR1

• [The effect of Mexidol on cerebral mitochondriogenesis at a young age and during aging]. / 2020 / PubMed / Full text

SUGCT

• Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype. / 09.2020 / PubMed / Full text

SULT1A1

• Bayesian association scan reveals loci associated with human lifespan and linked biomarkers. / 27.07.2017 / PubMed / Full text

SULT1E1

• Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes. / 02.2017 / PubMed / Full text

SULT2A1

• Sex-, age-, and race/ethnicity-dependent variations in drug-processing and NRF2-regulated genes in human livers. / 08.11.2020 / PubMed / Full text

SUMO1

• SUMO1-conjugation is altered during normal aging but not by increased amyloid burden. / 08.2018 / PubMed / Full text

SUMO2

• KSHV latent protein LANA2 inhibits sumo2 modification of p53. / 2015 / PubMed / Full text

SUN1

• Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging. / 26.02.2019 / PubMed / Full text

SUN2

• Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging. / 26.02.2019 / PubMed / Full text

SUSD1

• A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. / 07.2013 / PubMed / Full text

SUSD2

• Comparing the Effect of TGF-β Receptor Inhibition on Human Perivascular Mesenchymal Stromal Cells Derived from Endometrium, Bone Marrow and Adipose Tissues. / 01.12.2020 / PubMed / Full text

SV2B

• Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. / 10.2018 / PubMed / Full text

SV2C

• Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. / 10.2018 / PubMed / Full text

SYCP2

• Accelerated reproductive aging in females lacking a novel centromere protein [[SYCP2L]]. / 15.11.2015 / PubMed / Full text

SYCP2L

• Accelerated reproductive aging in females lacking a novel centromere protein [[SYCP2L]]. / 15.11.2015 / PubMed / Full text

SYCP3

• Effects of Saikokaryukotsuboreito on Spermatogenesis and Fertility in Aging Male Mice. / 05.04.2016 / PubMed / Full text

SYNE1

• Nesprin-1 impact on tumorigenic cell phenotypes. / 02.2020 / PubMed / Full text

SYNE2

• Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. / 03.2020 / PubMed / Full text

SYNJ2

• DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

SYT1

• Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins. / 2018 / PubMed / Full text

SYT4

• Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans. / 06.10.2015 / PubMed / Full text

SYT7

• Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells. / 28.02.2019 / PubMed / Full text

TAAR1

• Minimal Age-Related Alterations in Behavioral and Hematological Parameters in Trace Amine-Associated Receptor 1 (TAAR1) Knockout Mice. / 03.2020 / PubMed / Full text

TAC3

• Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. / 2015 / PubMed / Full text

TAF15

• FET proteins regulate lifespan and neuronal integrity. / 27.04.2016 / PubMed / Full text

TAF7

• Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. / 22.01.2020 / PubMed / Full text

TAF7L

• Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. / 22.01.2020 / PubMed / Full text

TANK

• Aging aggravated liver ischemia and reperfusion injury by promoting STING-mediated NLRP3 activation in macrophages. / 08.2020 / PubMed / Full text

TAP1

• Age-associated methylation change of TAP1 promoter in piglet. / 15.11.2015 / PubMed / Full text

TAP2

• Lifespan of mice and primates correlates with immunoproteasome expression. / 05.2015 / PubMed / Full text

TAS1R2

• Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. / 18.10.2018 / PubMed / Full text

TBC1D2

• Genome-wide association study identifies [i]SIAH3[/i] locus influencing the rate of ventricular enlargement in non-demented elders. / 11.11.2019 / PubMed / Full text

TBR1

• DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers. / 07.2017 / PubMed / Full text

TBX3

• Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex. / 29.05.2014 / PubMed / Full text

TCERG1

• The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity. / 17.07.2019 / PubMed / Full text

TCF15

• Loss of Neurogenesis in Aging Hydra. / 05.2019 / PubMed / Full text

TCF21

• Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3. / 22.06.2018 / PubMed / Full text

TCF7L1

• TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2. / 03.05.2017 / PubMed / Full text

TCP1

• Proteometabolomic characterization of apical bud maturation in Pinus pinaster. / 01.09.2020 / PubMed / Full text

TCTA

• Exciplex-Forming Cohost for High Efficiency and High Stability Phosphorescent Organic Light-Emitting Diodes. / 17.01.2018 / PubMed / Full text

TDRD1

• Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice. / 01.2020 / PubMed / Full text

TDRD6

• Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice. / 01.2020 / PubMed / Full text

TEAD4

• Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study. / 10.2013 / PubMed / Full text

TECPR2

• Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging. / 01-03.2019 / PubMed / Full text

TEP1

• [Influence of Age on the Susceptibility of Anopheles stephensi to Plasmodium berghei Infection]. / 12.2016 / PubMed

TERF2IP

• Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. / 11.2019 / PubMed / Full text

TESC

• Clonogenic Culture of Mouse Thymic Epithelial Cells. / 2019 / PubMed / Full text

TFAP2A

• Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites. / 2015 / PubMed / Full text

TFE3

• Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes. / 21.01.2020 / PubMed / Full text

TFG

• TFG-maintaining stability of overlooked FANCD2 confers early DNA-damage response. / 24.10.2020 / PubMed / Full text

TFPI

• Identification of cardiovascular health gene variants related to longevity in a Chinese population. / 07.09.2020 / PubMed / Full text

TGDS

• The evaluation and design of a short depression screening tool in Turkish older adults. / 10.2018 / PubMed / Full text

TGFB2

• Seminal plasma transforming growth factor-β, activin A and follistatin fluctuate within men over time. / 10.2016 / PubMed / Full text

TGFBR1

• Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text

TGM2

• Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text

THADA

• Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. / 29.09.2015 / PubMed / Full text

THBS1

• G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text

THBS4

• Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment. / 18.06.2019 / PubMed / Full text

THEMIS

• Lifetime benefits of early detection and treatment of diabetic kidney disease. / 2019 / PubMed / Full text

THPO

• Thrombopoietin is associated with δ's intercept, and only in Non-Hispanic Whites. / 2016 / PubMed / Full text

TIE1

• Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. / 2020 / PubMed / Full text

TIMP3

• Enhanced tissue regeneration potential of juvenile articular cartilage. / 11.2013 / PubMed / Full text

TINF2

• Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. / 04.2018 / PubMed / Full text

TJP1

• Morphological and immunohistochemical characteristics of the equine corneal epithelium. / 11.2019 / PubMed / Full text

TLR10

• Innate immune response to LPS in airway epithelium is dependent on chronological age and antecedent exposures. / 11.2013 / PubMed / Full text

TM9SF1

• Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats. / 06.2017 / PubMed / Full text

TMEM127

• Long-term prognosis of patients with pediatric pheochromocytoma. / 02.2014 / PubMed / Full text

TMEM135

• Mouse [i]Tmem135[/i] mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. / 15.11.2016 / PubMed / Full text

TMEM38B

• Genome wide association study of age at menarche in the Japanese population. / 2013 / PubMed / Full text

TMEM51

• Genome-wide analysis of DNA methylation profiles in a senescence-accelerated mouse prone 8 brain using whole-genome bisulfite sequencing. / 01.06.2017 / PubMed / Full text

TNFAIP3

• TNFAIP3 Plays a Role in Aging of the Hematopoietic System. / 2020 / PubMed / Full text

TNFRSF11B

• Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II). / 2016 / PubMed / Full text

TNFRSF1A

• Consumption of protein-enriched milk has minor effects on inflammation in older adults-A 12-week double-blind randomized controlled trial. / 03.2017 / PubMed / Full text

TNFSF13

• Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS. / 25.05.2017 / PubMed / Full text

TNFSF15

• Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens. / 11.2018 / PubMed / Full text

TNK1

• Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer's Disease. / 05.2018 / PubMed / Full text

TNKS2

• Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides. / 06.2020 / PubMed / Full text

TNNI1

• Regular aerobic exercise-ameliorated troponin I carbonylation to mitigate aged rat soleus muscle functional recession. / 05.2019 / PubMed / Full text

TNP1

• Cytological and molecular aspects of the ageing sperm. / 01.02.2019 / PubMed / Full text

TNP2

• Cytological and molecular aspects of the ageing sperm. / 01.02.2019 / PubMed / Full text

TNPO3

• Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

TNS3

• Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. / 10.2016 / PubMed / Full text

TOP3A

• Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing. / 08.10.2019 / PubMed / Full text

TOR2A

• The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. / 05.06.2018 / PubMed / Full text

TP53BP1

• Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus. / 18.05.2016 / PubMed / Full text

TP53INP1

• TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling. / 02.01.2019 / PubMed / Full text

TP53RK

• Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text

TP73

• G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text

TPCN1

• Effect of aging on calcium signaling in C57Bl6J mouse cerebral arteries. / 06.2013 / PubMed / Full text

TPP2

• Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency. / 29.01.2015 / PubMed / Full text

TPRKB

• Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text

TRAV1-2

• Human blood MAIT cell subsets defined using MR1 tetramers. / 05.2018 / PubMed / Full text

TRAV27

• Perturbed CD8 T cell immunity across universal influenza epitopes in the elderly. / 02.2018 / PubMed / Full text

TRBV19

• Perturbed CD8 T cell immunity across universal influenza epitopes in the elderly. / 02.2018 / PubMed / Full text

TREM1

• A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology. / 03.2015 / PubMed / Full text

TRHR

• Association between polymorphisms in the TRHR gene, fat-free mass, and muscle strength in older women. / 12.2013 / PubMed / Full text

TRIB2

• TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling. / 12.12.2018 / PubMed / Full text

TRIB3

• Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text

TRIM27

• TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination. / 04.12.2020 / PubMed / Full text

TRIOBP

• A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records. / 10.2016 / PubMed / Full text

TRPC1

• Ca entry via TRPC1 is essential for cellular differentiation and modulates secretion via the SNARE complex. / 01.07.2019 / PubMed / Full text

TRPC7

• Nociceptive transient receptor potential canonical 7 (TRPC7) mediates aging-associated tumorigenesis induced by ultraviolet B. / 01.2020 / PubMed / Full text

TRPM5

• Genetic strategies to analyze primary TRP channel-expressing cells in mice. / 11.2017 / PubMed / Full text

TRPS1

• miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence. / 01.2020 / PubMed / Full text

TRPV2

• The role of transient receptor potential vanilloid 2 channel in cardiac aging. / 10.2017 / PubMed / Full text

TSG101

• Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging. / 01.09.2019 / PubMed / Full text

TSHR

• TSH-independent release of thyroid hormones through cold exposure in aging rats. / 27.10.2017 / PubMed / Full text

TSPYL5

• Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text

TSSK6

• DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers. / 07.2017 / PubMed / Full text

TTF1

• Senescence and autophagy in usual interstitial pneumonia of different etiology. / 27.08.2020 / PubMed / Full text

TUBA1A

• Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text

TUBAL3

• Identification of biomarkers of human skin ageing in both genders. Wnt signalling - a label of skin ageing? / 2012 / PubMed / Full text

TWIST2

• DNA methylation abnormalities at gene promoters are extensive and variable in the elderly and phenocopy cancer cells. / 07.2014 / PubMed / Full text

TXK

• Phenotypic characteristics of aged CD4 CD28 T lymphocytes are determined by changes in the whole-genome DNA methylation pattern. / 04.2017 / PubMed / Full text

TXN

• Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice. / 15.11.2017 / PubMed / Full text

TXNDC5

• Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

TXNRD3

• Mitochondrial thioredoxin reductase 2 is elevated in long-lived primate as well as rodent species and extends fly mean lifespan. / 08.2017 / PubMed / Full text

TYK2

• Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. / 04.2018 / PubMed / Full text

TYMS

• C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins. / 03.2016 / PubMed / Full text

TYRO3

• The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia ([i]anx[/i]) mutation. / 01.05.2017 / PubMed / Full text

TYRP1

• Thymocid , a Standardized Black Cumin ([i]Nigella sativa[/i]) Seed Extract, Modulates Collagen Cross-Linking, Collagenase and Elastase Activities, and Melanogenesis in Murine B16F10 Melanoma Cells. / 19.07.2020 / PubMed / Full text

UACA

• Knockdown of [i]UACA[/i] inhibitsproliferation and invasion and promotes senescence of hepatocellular carcinoma cells. / 2018 / PubMed / Full text

UAP1

• Functional inactivation of UDP-N-acetylglucosamine pyrophosphorylase 1 (UAP1) induces early leaf senescence and defence responses in rice. / 02.2015 / PubMed / Full text

UBC

• Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text

UBE2C

• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

UBE2D2

• Stable reference genes in granulosa cells of bovine dominant follicles during follicular growth, FSH stimulation and maternal aging. / 04.2016 / PubMed / Full text

UBE2E3

• Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence. / 07.2018 / PubMed / Full text

UBE2N

• Aged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin. / 01.03.2015 / PubMed / Full text

UBE2T

• Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text

UBE4B

• CircRNAs in the tree shrew ([i]Tupaia belangeri[/i]) brain during postnatal development and aging. / 30.04.2018 / PubMed / Full text

UBN1

• O-linked N-acetylglucosamine transferase (OGT) interacts with the histone chaperone HIRA complex and regulates nucleosome assembly and cellular senescence. / 07.06.2016 / PubMed / Full text

UBP1

• Expression of potato RNA-binding proteins StUBA2a/b and StUBA2c induces hypersensitive-like cell death and early leaf senescence in Arabidopsis. / 07.2015 / PubMed / Full text

UBQLN2

• Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. / 24.02.2016 / PubMed / Full text

UBTD1

• UBTD1 induces cellular senescence through an UBTD1-Mdm2/p53 positive feedback loop. / 03.2015 / PubMed / Full text

UBTF

• Age-associated dysregulation of protein metabolism in the mammalian oocyte. / 12.2017 / PubMed / Full text

UBXN2B

• Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study. / 10.2013 / PubMed / Full text

UCHL3

• UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis. / 12.06.2018 / PubMed / Full text

UCHL5

• Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system. / 07.2016 / PubMed / Full text

UCN

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

UCN3

• Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise-induced threshold shift. / 08.2019 / PubMed / Full text

UGT1A6

• Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain. / 07.2015 / PubMed / Full text

UGT2B28

• Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a UGT2B28 genomic variation. / 05.12.2019 / PubMed / Full text

UGT2B7

• Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. / 05.2019 / PubMed / Full text

ULK2

• miR-26a suppresses autophagy in swine Sertoli cells by targeting ULK2. / 08.2018 / PubMed / Full text

UNC5C

• Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data. / 04.2017 / PubMed / Full text

UPF1

• Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity. / 21.08.2017 / PubMed / Full text

UPRT

• UPRT, a suicide-gene therapy candidate in higher eukaryotes, is required for Drosophila larval growth and normal adult lifespan. / 14.08.2015 / PubMed / Full text

UQCRC1

• Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone. / 07.2014 / PubMed / Full text

UQCRFS1

• Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. / 04.2014 / PubMed / Full text

USF1

• The rs2516839 variation of USF1 gene is associated with 4-year mortality of nonagenarian women: The Vitality 90 study. / 01.2019 / PubMed / Full text

USF2

• Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice. / 15.10.2018 / PubMed / Full text

USP15

• Deficiency of parkin and PINK1 impairs age-dependent mitophagy in [i]Drosophila[/i]. / 29.05.2018 / PubMed / Full text

USP28

• Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program. / 01.10.2017 / PubMed / Full text

USP30

• Deficiency of parkin and PINK1 impairs age-dependent mitophagy in [i]Drosophila[/i]. / 29.05.2018 / PubMed / Full text

USP4

• Increased Expression of Ubiquitin-Specific Protease 4 Participates in Neuronal Apoptosis After Intracerebral Hemorrhage in Adult Rats. / 04.2017 / PubMed / Full text

USP8

• Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction. / 04.2019 / PubMed / Full text

UTF1

• miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1. / 09.03.2017 / PubMed / Full text

UVRAG

• Essential role for UVRAG in autophagy and maintenance of cardiac function. / 01.01.2014 / PubMed / Full text

UVSSA

• A C. elegans homolog for the UV-hypersensitivity syndrome disease gene UVSSA. / 05.2016 / PubMed / Full text

VAMP2

• Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission. / 01.08.2018 / PubMed / Full text

VAMP8

• NUPR1 maintains autolysosomal efflux by activating SNAP25 transcription in cancer cells. / 2018 / PubMed / Full text

VAPB

• Transforming Cytosolic Proteins into "Insoluble" and Membrane-toxic Forms Triggering Diseases/Aging by Genetic, Pathological or Environmental Factors. / 2017 / PubMed / Full text

VAV3

• Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans. / 06.10.2015 / PubMed / Full text

VCL

• The effects of different preservation methods on ide (Leuciscus idus) sperm and the longevity of sperm movement. / 04.2018 / PubMed / Full text

VCPIP1

• Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging. / 03.09.2020 / PubMed / Full text

VDAC3

• VDAC3 As a Potential Marker of Mitochondrial Status Is Involved in Cancer and Pathology. / 2016 / PubMed / Full text

VEGFC

• Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

VEGFD

• Single-Arm Resistance Training Study to Determine the Relationship between Training Outcomes and Muscle Growth Factor mRNAs in Older Adults Consuming Numerous Medications and Supplements. / 2018 / PubMed / Full text

VHLL

• The Monetary Valuation of Lifetime Health Improvement and Life Expectancy Gains in Turkey. / 29.09.2017 / PubMed / Full text

VIT

• Autophagy-mediated longevity is modulated by lipoprotein biogenesis. / 2016 / PubMed / Full text

VPREB3

• Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text

VPS13C

• SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

VPS13D

• SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

VPS26A

• Characterization of novel markers of senescence and their prognostic potential in cancer. / 20.11.2014 / PubMed / Full text

VPS37B

• Identification of HIV infection-related DNA methylation sites and advanced epigenetic aging in HIV-positive, treatment-naive U.S. veterans. / 20.02.2017 / PubMed / Full text

VPS4A

• The expression changes of vacuolar protein sorting 4B (VPS4B) following middle cerebral artery occlusion (MCAO) in adult rats brain hippocampus. / 01.2014 / PubMed / Full text

VPS4B

• The expression changes of vacuolar protein sorting 4B (VPS4B) following middle cerebral artery occlusion (MCAO) in adult rats brain hippocampus. / 01.2014 / PubMed / Full text

VRK2

• Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy. / 22.09.2020 / PubMed / Full text

VSIG4

• Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue. / 10.2020 / PubMed / Full text

VSX1

• Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics. / 08.06.2016 / PubMed / Full text

WAC

• Implementation of Writing Across the Curriculum (WAC) learning approaches in social work and sociology gerontology courses. / 2013 / PubMed / Full text

WASL

• Loss of Wasl improves pancreatic cancer outcome. / 21.05.2020 / PubMed / Full text

WBP11

• Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs. / 05.03.2020 / PubMed / Full text

WDR48

• Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. / 15.04.2015 / PubMed / Full text

WDR5

• Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16 . / 11.2019 / PubMed / Full text

WDR73

• Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text

WDSUB1

• The complex genetics of gait speed: genome-wide meta-analysis approach. / 10.01.2017 / PubMed / Full text

WFDC2

• Differences in biomarkers and molecular pathways according to age for patients with HFrEF. / 01.10.2020 / PubMed / Full text

WIF1

• Identification of the mechanisms by which age alters the mechanosensitivity of mesenchymal stromal cells on substrates of differing stiffness: Implications for osteogenesis and angiogenesis. / 15.04.2017 / PubMed / Full text

WNK1

• Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2. / 10.2018 / PubMed / Full text

WNK4

• Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2. / 10.2018 / PubMed / Full text

WNT10A

• Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development. / 01.04.2020 / PubMed / Full text

WNT3

• Role of CD133 Molecule in Wnt Response and Renal Repair. / 03.2018 / PubMed / Full text

WNT5B

• Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development. / 01.04.2020 / PubMed / Full text

WNT7A

• Exogenous Expression of WNT7A in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents. / 2020 / PubMed / Full text

WWC1

• WWC1 genotype modulates age-related decline in episodic memory function across the adult life span. / 01.05.2014 / PubMed / Full text

XAF1

• XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence. / 02.02.2016 / PubMed / Full text

XG

• The effect of administration media on palatability and ease of swallowing of multiparticulate formulations. / 15.11.2018 / PubMed / Full text

XK

• Neurodegeneration in the elderly - When the blood type matters: An overview of the McLeod syndrome with focus on hematological features. / 06.2015 / PubMed / Full text

XPO1

• Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan. / 15.05.2018 / PubMed / Full text

XRCC2

• Copy neutral loss of heterozygosity is more frequent in older ovarian cancer patients. / 09.2013 / PubMed / Full text

XRCC5

• Repairing DNA damage by XRCC6/KU70 reverses TLR4-deficiency-worsened HCC development via restoring senescence and autophagic flux. / 01.06.2013 / PubMed / Full text

YBX2

• Preovulatory Aging In Vivo and In Vitro Affects Maturation Rates, Abundance of Selected Proteins, Histone Methylation Pattern and Spindle Integrity in Murine Oocytes. / 2016 / PubMed / Full text

YES1

• Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies. / 20.10.2018 / PubMed / Full text

ZAP70

• Increased ZAP70 Is Involved in Dry Skin Pruritus in Aged Mice. / 2016 / PubMed / Full text

ZBED6

• Correlation between ZBED6 Gene Upstream CpG Island methylation and mRNA expression in cattle. / 03.04.2017 / PubMed / Full text

ZBTB7A

• The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators. / 29.09.2020 / PubMed / Full text

ZC3H11A

• In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text

ZFHX3

• Shift work, DNA methylation and epigenetic age. / 01.10.2019 / PubMed / Full text

ZFP36L1

• Zinc finger protein ZFP36L1 promotes osteoblastic differentiation but represses adipogenic differentiation of mouse multipotent cells. / 28.03.2017 / PubMed / Full text

ZFPM2

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

ZIC1

• The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators. / 29.09.2020 / PubMed / Full text

ZNF14

• Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model. / 07.2014 / PubMed / Full text

ZNF207

• Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

ZNF211

• Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach. / 23.10.2020 / PubMed / Full text

ZNF367

• RNA-seq of the aging brain in the short-lived fish N. furzeri - conserved pathways and novel genes associated with neurogenesis. / 12.2014 / PubMed / Full text

ZNF396

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

ZNF467

• Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

ZNF483

• Genome wide association study of age at menarche in the Japanese population. / 2013 / PubMed / Full text

ZNF518B

• The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators. / 29.09.2020 / PubMed / Full text

ZNF616

• Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence. / 2015 / PubMed / Full text

ZNF619

• Differentially methylated gene patterns between age-matched sarcopenic and non-sarcopenic women. / 12.2019 / PubMed / Full text

ZNF644

• Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients. / 03.09.2019 / PubMed / Full text

ZNF704

• Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index. / 08.2015 / PubMed / Full text

ZPBP2

• Sex- and age-dependent DNA methylation at the 17q12-q21 locus associated with childhood asthma. / 07.2013 / PubMed / Full text

ZRSR2

• Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy. / 10.2016 / PubMed / Full text

ZSCAN4

• Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach. / 23.10.2020 / PubMed / Full text

ZW10

• Multivariate genomic scan implicates novel loci and haem metabolism in human ageing. / 16.07.2020 / PubMed / Full text