Aging genes 40-49

HP[править]

Astaxanthin Counteracts Vascular Calcification In Vitro Through an Early Up-Regulation of SOD2 Based on a Transcriptomic Approach. / 12.11.2020 / PubMed / Full text
A narrative review of highly processed food addiction across the lifespan. / 28.10.2020 / PubMed / Full text
Beta Human Papillomavirus 8E6 Attenuates LATS Phosphorylation after Failed Cytokinesis. / 01.06.2020 / PubMed / Full text
Cardiac baroreflex hysteresis is one of the determinants of the heart period variability asymmetry. / 01.10.2019 / PubMed / Full text
Aged rats with different performances at environmental enrichment onset display different modulation of habituation and aversive memory. / 05.2019 / PubMed / Full text
Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation. / 04.2019 / PubMed / Full text
Comparison between probabilistic and Wiener-Granger causality in assessing modifications of the cardiac baroreflex control with age. / 22.10.2018 / PubMed / Full text
CXCR3 CD8 T cells with naïve phenotype and high capacity for IFN-γ production are generated during homeostatic T-cell proliferation. / 10.2018 / PubMed / Full text
Mapping the Proxies of Memory and Learning Function in Senior Adults with High-performing, Normal Aging and Neurocognitive Disorders. / 2018 / PubMed / Full text
Role of Oral Nutritional Supplements Enriched with β-Hydroxy-β-Methylbutyrate in Maintaining Muscle Function and Improving Clinical Outcomes in Various Clinical Settings. / 2018 / PubMed / Full text
Effect of protein intake beyond habitual intakes following resistance training on cardiometabolic risk disease parameters in pre-conditioned older women. / 09.2018 / PubMed / Full text
Health care providers' perceptions of family caregivers' involvement in consultations within a geriatric hospital setting. / 07-08.2018 / PubMed / Full text
Influence of age and gender on the phase and strength of the relation between heart period and systolic blood pressure spontaneous fluctuations. / 01.03.2018 / PubMed / Full text
Species-specific role of gene-adjacent retroelements in human and mouse gastric carcinogenesis. / 15.04.2018 / PubMed / Full text
Associations of Helicobacter pylori infection and chronic atrophic gastritis with accelerated epigenetic ageing in older adults. / 10.10.2017 / PubMed / Full text
Aging Does Not Affect Axon Initial Segment Structure and Somatic Localization of Tau Protein in Hippocampal Neurons of Fischer 344 Rats. / 07-08.2017 / PubMed / Full text
Knee extensor power asymmetry is unrelated to functional mobility of older adults. / 11.2017 / PubMed / Full text
Reduced parahippocampal theta activity during spatial navigation in low, but not in high elderly performers. / 01.2018 / PubMed / Full text
The behavioral deficits and cognitive impairment are correlated with decreased IGF-II and ERK in depressed mice induced by chronic unpredictable stress. / 12.2017 / PubMed / Full text
The aminoestrogen prolame increases recognition memory and hippocampal neuronal spine density in aged mice. / 10.2017 / PubMed / Full text
The In Vitro Influence of a Genetic Superoxide-Hydrogen Peroxide Imbalance on Immunosenescence. / 08.2017 / PubMed / Full text
Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old. / 28.03.2017 / PubMed / Full text
Assessing the evolution of redundancy/synergy of spontaneous variability regulation with age. / 05.2017 / PubMed / Full text
Spatially dependent biotic and abiotic factors drive survivorship and physical structure of green roof vegetation. / 01.2017 / PubMed / Full text
Leucine supplementation enhances integrative myofibrillar protein synthesis in free-living older men consuming lower- and higher-protein diets: a parallel-group crossover study. / 12.2016 / PubMed / Full text
Copper accumulation in rodent brain astrocytes: A species difference. / 01.2017 / PubMed / Full text
Age-related individual variability in memory performance is associated with amygdala-hippocampal circuit function and emotional pattern separation. / 01.2017 / PubMed / Full text
Professionals' perspectives towards health promotion in residential aged care: an explorative study in Austria. / 01.04.2018 / PubMed / Full text
Energetics, Biomechanics, and Performance in Masters' Swimmers: A Systematic Review. / 07.2016 / PubMed / Full text
Estrogen-induced neuroprotective and anti-inflammatory effects are dependent on the brain areas of middle-aged female rats. / 06.2016 / PubMed / Full text
Transgenerational programming of longevity and reproduction by post-eclosion dietary manipulation in Drosophila. / 05.2016 / PubMed / Full text
[ENDOSCOPIC ANATOMY AND MORPHOLOGICAL CHANGES OF THE GASTRODUODENAL JUNCTION IN ULCER OF THE DUODENUM]. / 2015 / PubMed
1,3-Dinitrobenzene neurotoxicity - Passage effect in immortalized astrocytes. / 03.2016 / PubMed / Full text
The neural mechanisms underlying the aging-related enhancement of positive affects: electrophysiological evidences. / 2015 / PubMed / Full text
Flavonoid Chrysin prevents age-related cognitive decline via attenuation of oxidative stress and modulation of BDNF levels in aged mouse brain. / 07.2015 / PubMed / Full text
Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. / 06.2015 / PubMed / Full text
Hexosamine pathway and (ER) protein quality control. / 04.2015 / PubMed / Full text
Antioxidant activity, delayed aging, and reduced amyloid-β toxicity of methanol extracts of tea seed pomace from Camellia tenuifolia. / 05.11.2014 / PubMed / Full text
The Effects of Linguistic Context on Word Recognition in Noise by Elderly Listeners Using Spanish Sentence Lists (SSL). / 12.2015 / PubMed / Full text
Genetic relationships among traits related to reproduction and growth of Nelore females. / 15.09.2014 / PubMed / Full text
Aging Influence on Gray Matter Structural Associations within the Default Mode Network Utilizing Bayesian Network Modeling. / 2014 / PubMed / Full text
Promoting health in Georgia. / 03.2014 / PubMed / Full text
Predicting functional decline in older patients undergoing cardiac surgery. / 03.2014 / PubMed / Full text
Age influence on hypersensitivity pneumonitis induced in mice by exposure to Pantoea agglomerans. / 09.2013 / PubMed / Full text
Prognosis of hospitalised older people with different levels of functioning: a prospective cohort study. / 11.2013 / PubMed / Full text
Antiaging effects of astaxanthin-rich alga Haematococcus pluvialis on fruit flies under oxidative stress. / 14.08.2013 / PubMed / Full text
[Role of GDNF in the behavior and cognitive impairment of mice induced by chronic stress and aging]. / 01.2013 / PubMed
Identification of bovine hibernation-specific protein complex and evidence of its regulation in fasting and aging. / 05.2013 / PubMed / Full text
Consumer preferences for health and nonhealth outcomes of health promotion: results from a discrete choice experiment. / 01-02.2013 / PubMed / Full text

PCNA[править]

[Aryl hydrocarbon receptor interacting protein (AIP) in human dermis during aging.] / 2020 / PubMed
Impairment of Pol β-related DNA Base-excision Repair Leads to Ovarian Aging in Mice. / 20.11.2020 / PubMed / Full text
[Arylhydrocarbon receptor nuclear translocator (ARNT) in human skin during aging.] / 2020 / PubMed
Bone marrow mesenchymal stem cells improve thymus and spleen function of aging rats through affecting P21/PCNA and suppressing oxidative stress. / 19.06.2020 / PubMed / Full text
Regenerative and protective effects of dMSC-sEVs on high-glucose-induced senescent fibroblasts by suppressing RAGE pathway and activating Smad pathway. / 29.04.2020 / PubMed / Full text
[Heat shock protein 90 (HSP90) in age-dependent changes in the number of fibroblasts in human skin.] / 2020 / PubMed
A Higher Frequency Administration of the Nontoxic Cycloartane-Type Triterpene Argentatin A Improved Its Anti-Tumor Activity. / 14.04.2020 / PubMed / Full text
[Mechanosensitive protein of Hippo regulatory pathway - transcription coactivator with PZD-binding motif (TAZ) in human skin during aging.] / 2019 / PubMed
Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes. / 15.01.2020 / PubMed / Full text
[Mechanosensitive Yes-associated protein in human skin during aging.] / 2019 / PubMed
[Role of mechanosensitive protein Piezo1 in human age-dependent changes in the number of fibroblasts and blood vessels in human skin.] / 2019 / PubMed
Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells. / 11.2019 / PubMed / Full text
Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice. / 25.06.2019 / PubMed / Full text
[Transforming growth factor-β (TGF-β) in human skin in the process of aging.] / 2019 / PubMed
Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients. / 06.06.2019 / PubMed / Full text
High maternal milk intake in the postnatal life reduces the incidence of breast cancer during adulthood in rats. / 08.2019 / PubMed / Full text
Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice. / 15.04.2019 / PubMed / Full text
Age Influences Microglial Activation After Cuprizone-Induced Demyelination. / 2018 / PubMed / Full text
Genome Instability Is Promoted by the Chromatin-Binding Protein Spn1 in [i]Saccharomyces cerevisiae[/i]. / 12.2018 / PubMed / Full text
MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1. / 12.2018 / PubMed / Full text
Conditioned medium from stimulated macrophages inhibits growth but induces an inflammatory phenotype in breast cancer cells. / 10.2018 / PubMed / Full text
[Thyroid hormone receptors in human skin during aging.] / 2018 / PubMed
Xanthohumol exerts protective effects in liver alterations associated with aging. / 03.2019 / PubMed / Full text
Comparison of naturally aging and D-galactose induced aging model in beagle dogs. / 12.2017 / PubMed / Full text
An Extract from the Plant [i]Deschampsia antarctica[/i] Protects Fibroblasts from Senescence Induced by Hydrogen Peroxide. / 2017 / PubMed / Full text
[Age-related changes in the expression of lamin B receptors in fibroblasts of human dermis]. / 2017 / PubMed
Morphological alterations in the jejunal mucosa of aged rats and the possible protective role of green tea. / 2017 / PubMed / Full text
DNA damage tolerance in hematopoietic stem and progenitor cells in mice. / 15.08.2017 / PubMed / Full text
Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells. / 01.2018 / PubMed / Full text
Role of p38-MAPK pathway in the effects of high-magnitude compression on nucleus pulposus cell senescence in a disc perfusion culture. / 31.10.2017 / PubMed / Full text
Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson-Gilford Progeria Syndrome. / 15.07.2017 / PubMed / Full text
Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling. / 2015 / PubMed / Full text
Pubertal exposure to ethinylestradiol promotes different effects on the morphology of the prostate of the male and female gerbil during aging. / 02.2017 / PubMed / Full text
Argentatin B Inhibits Proliferation of Prostate and Colon Cancer Cells by Inducing Cell Senescence. / 27.11.2015 / PubMed / Full text
Microneedle fractional radiofrequency increases epidermal hyaluronan and reverses age-related epidermal dysfunction. / 02.2016 / PubMed / Full text
[POLYPEPTIDES INFLUENCE ON TISSUE CELL CULTURES REGENERATION OF VARIOUS AGE RATS]. / 2015 / PubMed
[Age-related peculiarities of the hypothalamo-hypophyseo-adrenal system in chronic heterotypic stress]. / 2015 / PubMed
Depletion of SIRT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes. / 08.2015 / PubMed / Full text
Possible intracellular regulators of female sexual maturation. / 2015 / PubMed / Full text
Profile of microRNAs associated with aging in rat liver. / 10.2014 / PubMed / Full text
Inhibition of stress induced premature senescence in presenilin-1 mutated cells with water soluble Coenzyme Q10. / 07.2014 / PubMed / Full text
Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis. / 09.2014 / PubMed / Full text
Low-power laser irradiation fails to improve liver regeneration in elderly rats at 48 h after 70 % resection. / 09.2015 / PubMed / Full text
Age-related changes in angiogenesis in human dermis. / 07.2014 / PubMed / Full text
No evidence for neo-oogenesis may link to ovarian senescence in adult monkey. / 11.2013 / PubMed / Full text
The role of small proliferative adipocytes in the development of obesity: comparison between Otsuka Long-Evans Tokushima Fatty (OLETF) rats and non-obese Long-Evans Tokushima Otsuka (LETO) rats. / 2013 / PubMed / Full text
Preventive effects of Monascus on androgen-related diseases: androgenetic alopecia, benign prostatic hyperplasia, and prostate cancer. / 08.05.2013 / PubMed / Full text
Changes of number of cells expressing proliferation and progenitor cell markers with age in rabbit intervertebral discs. / 05.2013 / PubMed / Full text

TF[править]

A preliminary investigation of the contribution of different tenderness factors to beef loin, tri-tip and heel tenderness. / 12.2020 / PubMed / Full text
The transcription factor ZmNAC126 accelerates leaf senescence downstream of the ethylene signalling pathway in maize. / 09.2020 / PubMed / Full text
Extensive transcriptome changes during seasonal leaf senescence in field-grown black cottonwood (Populus trichocarpa Nisqually-1). / 20.04.2020 / PubMed / Full text
Redox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A. / 05.2020 / PubMed / Full text
Expression of Transferrin and Albumin in the Sperm-Storage Tubules of Japanese Quail and their Possible Involvement in Long-Term Sperm Storage. / 25.01.2020 / PubMed / Full text
Atrial Fibrillation Progression Is Associated with Cell Senescence Burden as Determined by p53 and p16 Expression. / 23.12.2019 / PubMed / Full text
OsWRKY5 Promotes Rice Leaf Senescence via Senescence-Associated NAC and Abscisic Acid Biosynthesis Pathway. / 09.09.2019 / PubMed / Full text
BrTCP7 Transcription Factor Is Associated with MeJA-Promoted Leaf Senescence by Activating the Expression of [i]BrOPR3[/i] and [i]BrRCCR[/i]. / 14.08.2019 / PubMed / Full text
Activation of the Transcription of [i]BrGA20ox3[/i] by a BrTCP21 Transcription Factor Is Associated with Gibberellin-Delayed Leaf Senescence in Chinese Flowering Cabbage during Storage. / 08.08.2019 / PubMed / Full text
Anti-aging effects of long-term space missions, estimated by heart rate variability. / 20.06.2019 / PubMed / Full text
Transgenic expression of rice MYB102 (OsMYB102) delays leaf senescence and decreases abiotic stress tolerance in Arabidopsis thaliana. / 11.2019 / PubMed / Full text
Tomato fruit ripening factor NOR controls leaf senescence. / 09.05.2019 / PubMed / Full text
The WRKY transcription factor GhWRKY27 coordinates the senescence regulatory pathway in upland cotton (Gossypium hirsutum L.). / 29.03.2019 / PubMed / Full text
Effects of cerium oxide nanoparticles on hemostasis: Coagulation, platelets, and vascular endothelial cells. / 07.2019 / PubMed / Full text
Rice transcription factor OsMYB102 delays leaf senescence by down-regulating abscisic acid accumulation and signaling. / 09.05.2019 / PubMed / Full text
Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
Bioinformatic Analysis Reveals Key Genes and Pathways in Aging Brain of Senescence-accelerated Mouse P8 (SAMP8). / 2018 / PubMed / Full text
Cardiac regenerative capacity is age- and disease-dependent in childhood heart disease. / 2018 / PubMed / Full text
Comparing palm oil tocotrienol rich fraction with α-tocopherol supplementation on oxidative stress in healthy older adults. / 10.2017 / PubMed / Full text
The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice. / 12.06.2018 / PubMed / Full text
Comparing Palm Oil, Tocotrienol-Rich Fraction and α-Tocopherol Supplementation on the Antioxidant Levels of Older Adults. / 28.05.2018 / PubMed / Full text
Improved synaptic and cognitive function in aged 3 × Tg-AD mice with reduced amyloid-β after immunotherapy with a novel recombinant 6Aβ15-TF chimeric vaccine. / 08.2018 / PubMed / Full text
Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury. / 01.2019 / PubMed / Full text
Molecular and functional characterization of ShNAC1, an NAC transcription factor from Solanum habrochaites. / 06.2018 / PubMed / Full text
Characterization of a Transcriptional Regulator, BrWRKY6, Associated with Gibberellin-Suppressed Leaf Senescence of Chinese Flowering Cabbage. / 28.02.2018 / PubMed / Full text
Global mapping of transcription factor motifs in human aging. / 2018 / PubMed / Full text
MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors. / 2017 / PubMed / Full text
Cell reprogramming: Therapeutic potential and the promise of rejuvenation for the aging brain. / 11.2017 / PubMed / Full text
BrWRKY65, a WRKY Transcription Factor, Is Involved in Regulating Three Leaf Senescence-Associated Genes in Chinese Flowering Cabbage. / 08.06.2017 / PubMed / Full text
Replicative senescence promotes prothrombotic responses in endothelial cells: Role of NADPH oxidase- and cyclooxygenase-derived oxidative stress. / 07.2017 / PubMed / Full text
Senescence of Pancreas in Middle-Aged Rats with Normal Vascular Function. / 31.03.2017 / PubMed / Full text
Distinct Cell Stress Responses Induced by ATP Restriction in Quiescent Human Fibroblasts. / 2016 / PubMed / Full text
Age-Related Changes in Segmental Body Composition by Ethnicity and History of Weight Change across the Adult Lifespan. / 13.08.2016 / PubMed / Full text
Activation of Nrf2 contributes to the protective effect of Exendin-4 against angiotensin II-induced vascular smooth muscle cell senescence. / 01.10.2016 / PubMed / Full text
Network and biosignature analysis for the integration of transcriptomic and metabolomic data to characterize leaf senescence process in sunflower. / 06.06.2016 / PubMed / Full text
Severity and pattern of bone mineral loss in endocrine causes of osteoporosis as compared to age-related bone mineral loss. / 07-09.2016 / PubMed / Full text
Nitrogen remobilization and conservation, and underlying senescence-associated gene expression in the perennial switchgrass Panicum virgatum. / 07.2016 / PubMed / Full text
Rice ONAC106 Inhibits Leaf Senescence and Increases Salt Tolerance and Tiller Angle. / 12.2015 / PubMed / Full text
Age-related morphologic changes of the vertebral artery in the transverse process. Analysis by multidetector computed tomography angiography. / 01.09.2015 / PubMed / Full text
Regenerative Medicine for the Aging Brain. / 2014 / PubMed / Full text
Ultrafine carbon particle mediated cardiovascular impairment of aged spontaneously hypertensive rats. / 17.09.2014 / PubMed / Full text
RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells. / 21.11.2014 / PubMed / Full text
Epigenetic regulation of tissue factor inducibility in endothelial cell senescence. / 09.2014 / PubMed / Full text
The prognosis of dysphagia patients over 100 years old. / 09-10.2014 / PubMed / Full text
Gene regulatory cascade of senescence-associated NAC transcription factors activated by ETHYLENE-INSENSITIVE2-mediated leaf senescence signalling in Arabidopsis. / 07.2014 / PubMed / Full text
Patient needs and research priorities in the enteral nutrition market - a quantitative prioritization analysis. / 10.2014 / PubMed / Full text
Mutation of the Arabidopsis NAC016 transcription factor delays leaf senescence. / 10.2013 / PubMed / Full text

ABR[править]

[Hidden hearing loss and early identification]. / 07.2020 / PubMed / Full text
The effect and mechanism of 19S proteasome PSMD11/Rpn6 subunit in D-Galactose induced mimetic aging models. / 01.09.2020 / PubMed / Full text
Aging But Not Age-Related Hearing Loss Dominates the Decrease of Parvalbumin Immunoreactivity in the Primary Auditory Cortex of Mice. / 05-06.2020 / PubMed / Full text
Hearing loss through apoptosis of the spiral ganglion neurons in apolipoprotein E knockout mice fed with a western diet. / 12.03.2020 / PubMed / Full text
Effects of enriched endogenous omega-3 fatty acids on age-related hearing loss in mice. / 26.11.2019 / PubMed / Full text
Hearing impairment and associated morphological changes in pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice. / 10.10.2019 / PubMed / Full text
Global nurse/midwife workforce and reproductive health through social ecology lens. / 09.2019 / PubMed / Full text
Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise-induced threshold shift. / 08.2019 / PubMed / Full text
Age‑associated variation in the expression and function of TMEM16A calcium‑activated chloride channels in the cochlear stria vascularis of guinea pigs. / 08.2019 / PubMed / Full text
Hormone replacement therapy attenuates hearing loss: Mechanisms involving estrogen and the IGF-1 pathway. / 06.2019 / PubMed / Full text
Evidence for age-related cochlear synaptopathy in humans unconnected to speech-in-noise intelligibility deficits. / 15.03.2019 / PubMed / Full text
Masking Differentially Affects Envelope-following Responses in Young and Aged Animals. / 21.08.2018 / PubMed / Full text
Effects of Age on Speech-in-Noise Identification: Subjective Ratings of Hearing Difficulties and Encoding of Fundamental Frequency in Older Adults. / 06.2018 / PubMed / Full text
Age-Related Differences in Hearing Function and Cochlear Morphology between Male and Female Fischer 344 Rats. / 2017 / PubMed / Full text
The FBN rat model of aging: investigation of ABR waveforms and ribbon synapse changes. / 02.2018 / PubMed / Full text
Senescence-accelerated mouse prone 8 (SAMP8) as a model of age-related hearing loss. / 24.08.2017 / PubMed / Full text
Otoprotective effects of ethosuximide in NOD/LtJ mice with age-related hearing loss. / 07.2017 / PubMed / Full text
Involvement of p53 and Bcl-2 in sensory cell degeneration in aging rat cochleae. / 06.2017 / PubMed / Full text
Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations. / 01.2017 / PubMed / Full text
Reading ability reflects individual differences in auditory brainstem function, even into adulthood. / 01.2017 / PubMed / Full text
The effects of aging and sex on detection of ultrasonic vocalizations by adult CBA/CaJ mice (Mus musculus). / 11.2016 / PubMed / Full text
Effects of aging on peripheral and central auditory processing in rats. / 08.2016 / PubMed / Full text
Aging effects on the binaural interaction component of the auditory brainstem response in the Mongolian gerbil: Effects of interaural time and level differences. / 07.2016 / PubMed / Full text
The LEA protein, ABR, is regulated by ABI5 and involved in dark-induced leaf senescence in Arabidopsis thaliana. / 06.2016 / PubMed / Full text
Dietary intake of heat-killed Lactococcus lactis H61 delays age-related hearing loss in C57BL/6J mice. / 22.03.2016 / PubMed / Full text
Age-Related Changes in Binaural Interaction at Brainstem Level. / 07-08.2016 / PubMed / Full text
[Expression of Dynamin in the cochlea of mice of different ages]. / 07.2015 / PubMed
Hyperinsulinemia/diabetes, hearing, and aging in the University of Wisconsin calorie restriction monkeys. / 10.2015 / PubMed / Full text
Age-related changes of auditory brainstem responses in nonhuman primates. / 07.2015 / PubMed / Full text
Aging after noise exposure: acceleration of cochlear synaptopathy in "recovered" ears. / 13.05.2015 / PubMed / Full text
Prophylaxis in older Canadian adults with hemophilia A: lessons and more questions. / 2015 / PubMed / Full text
Age-related changes in auditory nerve-inner hair cell connections, hair cell numbers, auditory brain stem response and gap detection in UM-HET4 mice. / 30.04.2015 / PubMed / Full text
Accuracy of auditory steady state and auditory brainstem responses to detect the preventive effect of polyphenols on age-related hearing loss in Sprague-Dawley rats. / 02.2016 / PubMed / Full text
Auditory brainstem gap responses start to decline in mice in middle age: a novel physiological biomarker for age-related hearing loss. / 07.2015 / PubMed / Full text
Age-related neurochemical changes in the rhesus macaque superior olivary complex. / 20.12.2013 / PubMed / Full text
Age-related changes in the relationship between auditory brainstem responses and envelope-following responses. / 08.2014 / PubMed / Full text
Age-related neurochemical changes in the rhesus macaque inferior colliculus. / 2014 / PubMed / Full text
Stability and plasticity of auditory brainstem function across the lifespan. / 06.2015 / PubMed / Full text
Age-related hearing loss: GABA, nicotinic acetylcholine and NMDA receptor expression changes in spiral ganglion neurons of the mouse. / 14.02.2014 / PubMed / Full text
Ups and downs of Viagra: revisiting ototoxicity in the mouse model. / 2013 / PubMed / Full text
Compound heterozygosity of the functionally null Cdh23(v-ngt) and hypomorphic Cdh23(ahl) alleles leads to early-onset progressive hearing loss in mice. / 2013 / PubMed / Full text
Age-related neurochemical changes in the rhesus macaque cochlear nucleus. / 01.05.2014 / PubMed / Full text
Hair cell overexpression of Islet1 reduces age-related and noise-induced hearing loss. / 18.09.2013 / PubMed / Full text
Age-related hearing loss in Mn-SOD heterozygous knockout mice. / 2013 / PubMed / Full text
Prolactin expression in the cochlea of aged BALB/c mice is gender biased and correlates to loss of bone mineral density and hearing loss. / 2013 / PubMed / Full text
Age-related hearing loss in rhesus monkeys is correlated with cochlear histopathologies. / 2013 / PubMed / Full text

CD34[править]

Comparing the Effect of TGF-β Receptor Inhibition on Human Perivascular Mesenchymal Stromal Cells Derived from Endometrium, Bone Marrow and Adipose Tissues. / 01.12.2020 / PubMed / Full text
ACE2/ACE imbalance and impaired vasoreparative functions of stem/progenitor cells in aging. / 27.11.2020 / PubMed / Full text
Innovative Mind-Body Intervention Day Easy Exercise Increases Peripheral Blood CD34 Cells in Adults. / 01-12.2020 / PubMed / Full text
Human Thymic Involution and Aging in Humanized Mice. / 2020 / PubMed / Full text
Coinhibition of activated p38 MAPKα and mTORC1 potentiates stemness maintenance of HSCs from SR1-expanded human cord blood CD34 cells via inhibition of senescence. / 12.2020 / PubMed / Full text
Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype. / 09.2020 / PubMed / Full text
Phenotypic Analysis of the Mouse Hematopoietic Hierarchy Using Spectral Cytometry: From Stem Cell Subsets to Early Progenitor Compartments. / 10.2020 / PubMed / Full text
Mesenchymal stem cells repair bone marrow damage of aging rats and regulate autophagy and aging genes. / 08.2020 / PubMed / Full text
Effects of continuous exposure to low concentration of ClO gas on the growth, viability, and maintenance of undifferentiated MSCs in long-term cultures. / 06.2020 / PubMed / Full text
Immune cell extracellular vesicles and their mitochondrial content decline with ageing. / 2020 / PubMed / Full text
Young and elderly oral squamous cell carcinoma patients present similar angiogenic profile and predominance of M2 macrophages: Comparative immunohistochemical study. / 12.2019 / PubMed / Full text
HIV-mediated immune aging in young adults infected perinatally or during childhood. / 01.09.2019 / PubMed / Full text
Immunophenotypic characterization, multi-lineage differentiation and aging of zebrafish heart and liver tissue-derived mesenchymal stem cells as a novel approach in stem cell-based therapy. / 04.2019 / PubMed / Full text
Cardio-ankle vascular index and circulating CD34-positive cell levels as indicators of endothelial repair activity in older Japanese men. / 06.2019 / PubMed / Full text
Role of apoptotic, autophagic and senescence pathways in minor salivary gland adenoid cystic carcinoma. / 08.02.2019 / PubMed / Full text
Dynamic regulation of NOTCH1 activation and Notch ligand expression in human thymus development. / 13.08.2018 / PubMed / Full text
Therapeutic efficacy of olfactory stem cells in rotenone induced Parkinsonism in adult male albino rats. / 07.2018 / PubMed / Full text
Gender and age-related cell compositional differences in C57BL/6 murine adipose tissue stromal vascular fraction. / 2018 / PubMed / Full text
Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence. / 09.2018 / PubMed / Full text
Precise Intradermal Injection of Nanofat-Derived Stromal Cells Combined with Platelet-Rich Fibrin Improves the Efficacy of Facial Skin Rejuvenation. / 2018 / PubMed / Full text
Human nail stem cells are retained but hypofunctional during aging. / 06.2018 / PubMed / Full text
Hair Follicle Stem Cell Faith Is Dependent on Chromatin Remodeling Capacity Following Low-Dose Radiation. / 04.2018 / PubMed / Full text
Developmental differences between neonatal and adult human erythropoiesis. / 08.2018 / PubMed / Full text
Normal variation of bone marrow B-cell precursors according to age - reference ranges for studies in myelodysplastic syndromes in Brazil. / 09.2018 / PubMed / Full text
Aging process, adherence to Mediterranean diet and nutritional status in a large cohort of nonagenarians: Effects on endothelial progenitor cells. / 01.2018 / PubMed / Full text
Lower resting and exercise-induced circulating angiogenic progenitors and angiogenic T cells in older men. / 01.03.2018 / PubMed / Full text
HIV-1 p55-gag protein induces senescence of human bone marrow mesenchymal stem cells and reduces their capacity to support expansion of hematopoietic stem cells in vitro. / 09.2017 / PubMed / Full text
SOX17 Regulates Conversion of Human Fibroblasts Into Endothelial Cells and Erythroblasts by Dedifferentiation Into CD34 Progenitor Cells. / 20.06.2017 / PubMed / Full text
Platelets and circulating CD34-positive cells as an indicator of the activity of the vicious cycle between hypertension and endothelial dysfunction in elderly Japanese men. / 04.2017 / PubMed / Full text
Factors that may influence polymorphous low-grade adenocarcinoma growth. / 04.2017 / PubMed / Full text
Age-dependent cellular reactions of the human immune system of humanized NOD scid gamma mice on LPS stimulus. / 04.2017 / PubMed / Full text
Telomere Shortening, Regenerative Capacity, and Cardiovascular Outcomes. / 31.03.2017 / PubMed / Full text
Exercise restores muscle stem cell mobilization, regenerative capacity and muscle metabolic alterations via adiponectin/AdipoR1 activation in SAMP10 mice. / 06.2017 / PubMed / Full text
Expression Analysis of the Stem Cell Marker Pw1/Peg3 Reveals a CD34 Negative Progenitor Population in the Hair Follicle. / 04.2017 / PubMed / Full text
Age-Related Renal Microvascular Changes: Evaluation by Three-Dimensional Digital Imaging of the Human Renal Microcirculation Using Virtual Microscopy. / 02.11.2016 / PubMed / Full text
Constitutive Expression of Inducible Cyclic Adenosine Monophosphate Early Repressor (ICER) in Cycling Quiescent Hematopoietic Cells: Implications for Aging Hematopoietic Stem Cells. / 02.2017 / PubMed / Full text
Age and Human Regenerative Capacity Impact of Cardiovascular Risk Factors. / 16.09.2016 / PubMed / Full text
Endothelial Progenitor Cell Levels Predict Future Physical Function: An Exploratory Analysis From the VA Enhanced Fitness Study. / 03.2016 / PubMed / Full text
Renal resistive index correlates with peritubular capillary loss and arteriosclerosis in biopsy tissues from patients with chronic kidney disease. / 12.2015 / PubMed / Full text
The Mechanism of Ligamentum Flavum Hypertrophy: Introducing Angiogenesis as a Critical Link That Couples Mechanical Stress and Hypertrophy. / 08.2015 / PubMed / Full text
Quantification of nucleated cells, CD34-positive cells and CFU-GM colonies in single bone marrow samples and bone marrow harvests derived from healthy children. / 05.2014 / PubMed / Full text
Loss of CD34 expression in aging human choriocapillaris endothelial cells. / 2014 / PubMed / Full text
Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing. / 01.2014 / PubMed / Full text
Age-related changes in the features of porcine adult stem cells isolated from adipose tissue and skeletal muscle. / 01.10.2013 / PubMed / Full text
Lower levels of circulating progenitor cells are associated with low physical function and performance in elderly men with impaired glucose tolerance: a pilot substudy from the VA Enhanced Fitness trial. / 12.2013 / PubMed / Full text
Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: a possible marker of hair follicle development. / 02.2013 / PubMed / Full text

EGF[править]

Acute, exercise-induced alterations in cytokines and chemokines in the blood distinguish physically active and sedentary aging. / 08.12.2020 / PubMed / Full text
Proinflammation, profibrosis, and arterial aging. / 09.2020 / PubMed / Full text
Hinokitiol induces cell death and inhibits epidermal growth factor-induced cell migration and signaling pathways in human cervical adenocarcinoma. / 09.2020 / PubMed / Full text
Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor. / 10.2020 / PubMed / Full text
Activation of epidermal growth factor receptor signaling mediates cellular senescence induced by certain pro-inflammatory cytokines. / 05.2020 / PubMed / Full text
Insulin Signaling in Intestinal Stem and Progenitor Cells as an Important Determinant of Physiological and Metabolic Traits in [i]Drosophila[/i]. / 26.03.2020 / PubMed / Full text
Different cellular properties and loss of nuclear signalling of porcine epidermal growth factor receptor with aging. / 01.05.2020 / PubMed / Full text
Isoform-selective as opposed to complete depletion of fibroblast growth factor 2 (FGF-2) has no major impact on survival and gene expression in SOD1 amyotrophic lateral sclerosis mice. / 09.2019 / PubMed / Full text
A novel age-related venous amyloidosis derived from EGF-containing fibulin-like extracellular matrix protein 1. / 04.2019 / PubMed / Full text
EGF/EGFR upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence. / 04.12.2018 / PubMed / Full text
Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults. / 09.2018 / PubMed / Full text
The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma. / 2019 / PubMed / Full text
Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling. / 02.11.2018 / PubMed / Full text
Burn wounds in the young versus the aged patient display differential immunological responses. / 09.2018 / PubMed / Full text
Precise Intradermal Injection of Nanofat-Derived Stromal Cells Combined with Platelet-Rich Fibrin Improves the Efficacy of Facial Skin Rejuvenation. / 2018 / PubMed / Full text
RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells. / 13.03.2018 / PubMed / Full text
Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor. / 09.03.2018 / PubMed / Full text
VEGF Signaling in Neurological Disorders. / 17.01.2018 / PubMed / Full text
Global analysis of gene expression profiles in the submandibular salivary gland of klotho knockout mice. / 04.2018 / PubMed / Full text
Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans. / 29.08.2017 / PubMed / Full text
Skin-resident stem cells and wound healing. / 2017 / PubMed / Full text
[Signal molecules of endometrium: gerontological and general pathhological aspects]. / 2015 / PubMed
Neuron-specific knockdown of the Drosophila fat induces reduction of life span, deficient locomotive ability, shortening of motoneuron terminal branches and defects in axonal targeting. / 07.2017 / PubMed / Full text
Decline in Proliferation and Immature Neuron Markers in the Human Subependymal Zone during Aging: Relationship to EGF- and FGF-Related Transcripts. / 2016 / PubMed / Full text
Phosphorylation of MITF by AKT affects its downstream targets and causes TP53-dependent cell senescence. / 11.2016 / PubMed / Full text
Regeneration and Carcinogenesis. / 2015 / PubMed
Loss of Maspardin Attenuates the Growth and Maturation of Mouse Cortical Neurons. / 2016 / PubMed / Full text
Whole-transcriptome analysis of mouse adipose tissue in response to short-term caloric restriction. / 04.2016 / PubMed / Full text
Biomarkers related to immunosenescence: relationships with therapy and survival in lung cancer patients. / 01.2016 / PubMed / Full text
Selective coexpression of VEGF receptor 2 in EGFRvIII-positive glioblastoma cells prevents cellular senescence and contributes to their aggressive nature. / 05.2016 / PubMed / Full text
Interleukin-6 as a first-rated serum inflammatory marker to predict mortality and hospitalization in the oldest old: A regression and CART approach in the BELFRAIL study. / 09.2015 / PubMed / Full text
Age-dependent Müller glia neurogenic competence in the mouse retina. / 10.2015 / PubMed / Full text
Development of a chemically defined in vitro culture system to effectively stimulate the proliferation of adult human dermal fibroblasts. / 07.2015 / PubMed / Full text
Comparison of the effect of multicomponent and resistance training programs on metabolic health parameters in the elderly. / 05-06.2015 / PubMed / Full text
Effect of aging and cardiovascular risk factors on receptor Tie1 expression in human erectile tissue. / 04.2015 / PubMed / Full text
Royalactin extends lifespan of Caenorhabditis elegans through epidermal growth factor signaling. / 12.2014 / PubMed / Full text
The expression of epidermal growth factor (EGF) and its receptor (EGFR) during post-natal testes development in the yak. / 12.2014 / PubMed / Full text
The role of growth factors in maintenance of stemness in bone marrow-derived mesenchymal stem cells. / 28.02.2014 / PubMed / Full text
Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7. / 20.12.2013 / PubMed / Full text
Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR). / 01.11.2013 / PubMed / Full text
Clinical significance of proliferation, apoptosis and senescence of nasopharyngeal cells by the simultaneously blocking EGF, IGF-1 receptors and Bcl-xl genes. / 01.11.2013 / PubMed / Full text
Molecular diversity subdivides the adult forebrain neural stem cell population. / 01.2014 / PubMed / Full text
Can proteomics yield insight into aging aorta? / 08.2013 / PubMed / Full text
The mitogen-inducible gene-6 is involved in regulation of cellular senescence in normal diploid fibroblasts. / 10.2013 / PubMed / Full text
Targeted endometrial cancer therapy as a future prospect. / 03.2013 / PubMed / Full text
Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. / 04-05.2013 / PubMed / Full text

CD44[править]

Hyaluronan goes to great length. / 17.07.2020 / PubMed / Full text
Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties. / 12.05.2020 / PubMed / Full text
Maturity-dependent cartilage cell plasticity and sensitivity to external perturbation. / 06.2020 / PubMed / Full text
Aged Mice Exhibit Severe Exacerbations of Dry Eye Disease with an Amplified Memory Th17 Cell Response. / 07.2020 / PubMed / Full text
Effects of continuous exposure to low concentration of ClO gas on the growth, viability, and maintenance of undifferentiated MSCs in long-term cultures. / 06.2020 / PubMed / Full text
Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice. / 13.02.2020 / PubMed / Full text
Characterization of human telomerase reverse transcriptase immortalized anterior cruciate ligament cell lines. / 12.2019 / PubMed / Full text
Effect of Allogenic Bone Marrow Mesenchymal Stem Cell Transplantation on T Cells of Old Mice. / 02.2020 / PubMed / Full text
The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPR . / 27.11.2019 / PubMed / Full text
Defective induction of the proteasome associated with T-cell receptor signaling underlies T-cell senescence. / 12.2019 / PubMed / Full text
CD44v8-10 and CD44s Are Age-dependently Expressed in Primary Cultured Papillary Thyroid Carcinoma Cells and Are Associated with Cell Proliferation. / 25.04.2019 / PubMed / Full text
Immunophenotypic characterization, multi-lineage differentiation and aging of zebrafish heart and liver tissue-derived mesenchymal stem cells as a novel approach in stem cell-based therapy. / 04.2019 / PubMed / Full text
CD8 , but not CD4 effector/memory T cells, express the [[CD44]] CD45RB phenotype with aging, which displays reduced expression levels of P2X receptor and ATP-induced cellular responses. / 03.2019 / PubMed / Full text
Regenerative potential of human nucleus pulposus resident stem/progenitor cells declines with ageing and intervertebral disc degeneration. / 10.2018 / PubMed / Full text
Multi-color flow cytometry for evaluating age-related changes in memory lymphocyte subsets in dogs. / 10.2018 / PubMed / Full text
Therapeutic efficacy of olfactory stem cells in rotenone induced Parkinsonism in adult male albino rats. / 07.2018 / PubMed / Full text
Precise Intradermal Injection of Nanofat-Derived Stromal Cells Combined with Platelet-Rich Fibrin Improves the Efficacy of Facial Skin Rejuvenation. / 2018 / PubMed / Full text
Some chemotherapeutics-treated colon cancer cells display a specific phenotype being a combination of stem-like and senescent cell features. / 02.01.2018 / PubMed / Full text
A Trickster in Disguise: Hyaluronan's Ambivalent Roles in the Matrix. / 2017 / PubMed / Full text
Longevity effect of a polysaccharide from Chlorophytum borivilianum on Caenorhabditis elegans and Saccharomyces cerevisiae. / 2017 / PubMed / Full text
Physiologic Thymic Involution Underlies Age-Dependent Accumulation of Senescence-Associated CD4 T Cells. / 01.07.2017 / PubMed / Full text
CD44 alveolar type II cells show stem cell properties during steady-state alveolar homeostasis. / 01.07.2017 / PubMed / Full text
Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line. / 04.05.2017 / PubMed / Full text
Sialylation regulates myofibroblast differentiation of human skin fibroblasts. / 18.04.2017 / PubMed / Full text
Calorie Restriction Attenuates Terminal Differentiation of Immune Cells. / 2016 / PubMed / Full text
Identification and characterization of adult mouse meniscus stem/progenitor cells. / 05-07.2017 / PubMed / Full text
Development and mechanistic insight into enhanced cytotoxic potential of hyaluronic acid conjugated nanoparticles in CD44 overexpressing cancer cells. / 15.01.2017 / PubMed / Full text
Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role. / 06.2017 / PubMed / Full text
Disentangling the aneuploidy and senescence paradoxes: a study of triploid breast cancers non-responsive to neoadjuvant therapy. / 04.2016 / PubMed / Full text
Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8 T cells in aged mice. / 02.02.2016 / PubMed / Full text
Characterization of age-associated exhausted CD8⁺ T cells defined by increased expression of Tim-3 and PD-1. / 04.2016 / PubMed / Full text
miR-34a inhibits differentiation of human adipose tissue-derived stem cells by regulating cell cycle and senescence induction. / 11-12.2015 / PubMed / Full text
Microneedle fractional radiofrequency increases epidermal hyaluronan and reverses age-related epidermal dysfunction. / 02.2016 / PubMed / Full text
Age-independent effects of hyaluronan amide derivative and growth hormone on human osteoarthritic chondrocytes. / 11.2015 / PubMed / Full text
Changes in glomerular parietal epithelial cells in mouse kidneys with advanced age. / 15.07.2015 / PubMed / Full text
In vitro 3-D model based on extending time of culture for studying chronological epidermis aging. / 09.2015 / PubMed / Full text
Premature aging induced by radiation exhibits pro-atherosclerotic effects mediated by epigenetic activation of CD44 expression. / 10.2014 / PubMed / Full text
Hyaluronan enhances wound repair and increases collagen III in aged dermal wounds. / 07-08.2014 / PubMed / Full text
Metzincins and related genes in experimental renal ageing: towards a unifying fibrosis classifier across species. / 06.2014 / PubMed / Full text
Immunohistochemical patterns in the interfollicular Caucasian scalps: influences of age, gender, and alopecia. / 2013 / PubMed / Full text
Human leukemic cell lines synthesize hyaluronan to avoid senescence and resist chemotherapy. / 12.2013 / PubMed / Full text
Mice with heterozygous deficiency of manganese superoxide dismutase (SOD2) have a skin immune system with features of "inflamm-aging". / 03.2014 / PubMed / Full text
Selective matrix (hyaluronan) interaction with CD44 and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction. / 10.2013 / PubMed / Full text
Intrinsic defects in CD8 T cells with aging contribute to impaired primary antiviral responses. / 06.2013 / PubMed / Full text
Rejuvenation of aged pig facial skin by transplanting allogeneic granulocyte colony-stimulating factor-induced peripheral blood stem cells from a young pig. / 2013 / PubMed / Full text

NGF[править]

Dietary fish hydrolysate supplementation containing n-3 LC-PUFAs and peptides prevents short-term memory and stress response deficits in aged mice. / 23.09.2020 / PubMed / Full text
Imbalance of nerve growth factor metabolism in aging women with overactive bladder syndrome. / 01.09.2020 / PubMed / Full text
Parity Attenuates Intraepithelial Corneal Sensory Nerve Loss in Female Mice. / 21.07.2020 / PubMed / Full text
Cholinergic System and NGF Receptors: Insights from the Brain of the Short-Lived Fish [i]Nothobranchius furzeri[/i]. / 20.06.2020 / PubMed / Full text
Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice. / 08.04.2020 / PubMed / Full text
Retrograde axonal transport of BDNF and proNGF diminishes with age in basal forebrain cholinergic neurons. / 12.2019 / PubMed / Full text
C-SH2 point mutation converts p85β regulatory subunit of phosphoinositide 3-kinase to an anti-aging gene. / 03.09.2019 / PubMed / Full text
[i]Hericium erinaceus[/i] Mycelium and Its Isolated Compound, Erinacine A, Ameliorate High-Fat High-Sucrose Diet-Induced Metabolic Dysfunction and Spatial Learning Deficits in Aging Mice. / 05.2019 / PubMed / Full text
Morphological and immunohistochemical characteristics of the equine corneal epithelium. / 11.2019 / PubMed / Full text
Ectopic nerve growth factor prevents proliferation in glioma cells by senescence induction. / 05.2019 / PubMed / Full text
Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway. / 10.10.2018 / PubMed / Full text
Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling. / 02.11.2018 / PubMed / Full text
Nasal delivery of nerve growth factor rescue hypogonadism by up-regulating GnRH and testosterone in aging male mice. / 09.2018 / PubMed / Full text
Evidence for changing nerve growth factor signalling mechanisms during development, maturation and ageing in the rat molar pulp. / 02.2019 / PubMed / Full text
Reduced NGF in Gastric Endothelial Cells Is One of the Main Causes of Impaired Angiogenesis in Aging Gastric Mucosa. / 2018 / PubMed / Full text
Anti-nerve growth factor does not change physical activity in normal young or aging mice but does increase activity in mice with skeletal pain. / 11.2018 / PubMed / Full text
Effects of cerebrolysin on nerve growth factor system in the aging rat brain. / 2017 / PubMed / Full text
Immunohistochemical localization of nerve growth factor, tropomyosin receptor kinase A, and p75 in the bone and articular cartilage of the mouse femur. / 01-12.2017 / PubMed / Full text
Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease. / 12.2017 / PubMed / Full text
Noni (Morinda citrifolia L.) fruit juice reverses age-related decline in neural-immune interactions in the spleens of old F344 rats. / 23.02.2017 / PubMed / Full text
Morphine exposure during early life alters thermal and mechanical thresholds in rats. / 08.2017 / PubMed / Full text
Age-Related (Aged vs. Adult) Comparison of the Effect of Two Mild Stressors on the Nerve Growth Factor (NGF) in the Rat Hypothalamic Supraoptic Nucleus (SON) - Immunohistochemical Study. / 2016 / PubMed
The effects of short-term JNK inhibition on the survival and growth of aged sympathetic neurons. / 10.2016 / PubMed / Full text
Estrogen-induced neuroprotective and anti-inflammatory effects are dependent on the brain areas of middle-aged female rats. / 06.2016 / PubMed / Full text
Increased ZAP70 Is Involved in Dry Skin Pruritus in Aged Mice. / 2016 / PubMed / Full text
The impact of two mild stressors on the nerve growth factor (NGF) immunoreactivity in the amygdala in aged rats compared to adult ones. / 04.2016 / PubMed / Full text
Prolonged metformin treatment leads to reduced transcription of Nrf2 and neurotrophic factors without cognitive impairment in older C57BL/6J mice. / 15.03.2016 / PubMed / Full text
High-pressure physiological saline isotonic solution administration enhances brain NGF and NGF-receptors expression. / 10.2015 / PubMed
The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease. / 09.2015 / PubMed / Full text
The Relationship Between Variation in Size of the Primordial Follicle Pool and Age at Natural Menopause. / 06.2015 / PubMed / Full text
Time dynamics of protein complexes in the AD11 transgenic mouse model for Alzheimer's disease like pathology. / 29.04.2015 / PubMed / Full text
The effect of mild stress stimulation on the nerve growth factor (NGF) and tyrosine kinase receptor A (TrkA) immunoreactivity in the paraventricular nucleus (PVN) of the hypothalamus and hippocampus in aged vs. adult rats. / 02.04.2015 / PubMed / Full text
Nerve growth factor in the adult brain of a teleostean model for aging research: Nothobranchius furzeri. / 07.2014 / PubMed / Full text
Age-dependent effects of valproic acid in Alzheimer's disease (AD) mice are associated with nerve growth factor (NGF) regulation. / 25.04.2014 / PubMed / Full text
Validation of the power model of ovarian nongrowing follicle depletion associated with aging in women. / 03.2014 / PubMed / Full text
Association of inflammaging (inflammation aging) with higher prevalence of OAB in elderly population. / 05.2014 / PubMed / Full text
Transplantation of human adipose tissue-derived stem cells delays clinical onset and prolongs life span in ALS mouse model. / 2014 / PubMed / Full text
The proform of glia cell line-derived neurotrophic factor: a potentially biologically active protein. / 02.2014 / PubMed / Full text
Improvement of cognitive function and physical activity of aging mice by human neural stem cells over-expressing choline acetyltransferase. / 11.2013 / PubMed / Full text
Reduced serum nerve growth factor in patients with late-life depression. / 05.2013 / PubMed / Full text
Sciatic nerve regeneration is not inhibited by anti-NGF antibody treatment in the adult rat. / 25.06.2013 / PubMed / Full text
Menstrual cycle and reproductive aging alters immune reactivity, NGF expression, antioxidant enzyme activities, and intracellular signaling pathways in the peripheral blood mononuclear cells of healthy women. / 08.2013 / PubMed / Full text
ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice. / 08.2013 / PubMed / Full text
BDNF transcripts, proBDNF and proNGF, in the cortex and hippocampus throughout the life span of the rat. / 12.2013 / PubMed / Full text
Diminished trkA receptor signaling reveals cholinergic-attentional vulnerability of aging. / 01.2013 / PubMed / Full text

PINK1[править]

Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in [i]C. elegans[/i]. / 09.09.2020 / PubMed / Full text
Female mice are resilient to age-related decline of substantia nigra dopamine neuron firing parameters. / 11.2020 / PubMed / Full text
Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration. / 09.2020 / PubMed / Full text
SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy. / 18.07.2020 / PubMed / Full text
Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster. / 23.09.2020 / PubMed / Full text
Compression-induced senescence of nucleus pulposus cells by promoting mitophagy activation via the PINK1/PARKIN pathway. / 05.2020 / PubMed / Full text
Doxorubicin-induced normal breast epithelial cellular aging and its related breast cancer growth through mitochondrial autophagy and oxidative stress mitigated by ginsenoside Rh2. / 07.2020 / PubMed / Full text
miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1. / 12.03.2020 / PubMed / Full text
Mitochondrial DNA heteroplasmy rises in substantial nigra of aged PINK1 KO mice. / 22.01.2020 / PubMed / Full text
Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice. / 15.12.2019 / PubMed / Full text
[i]Malassezia[/i] and Parkinson's Disease. / 2019 / PubMed / Full text
Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. / 01.10.2019 / PubMed / Full text
SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
Neuronal Mitophagy: Lessons from a Pathway Linked to Parkinson's Disease. / 08.2019 / PubMed / Full text
Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction. / 04.2019 / PubMed / Full text
Oligonol Alleviates Sarcopenia by Regulation of Signaling Pathways Involved in Protein Turnover and Mitochondrial Quality. / 05.2019 / PubMed / Full text
AMP Kinase Activation is Selectively Disrupted in the Ventral Midbrain of Mice Deficient in Parkin or PINK1 Expression. / 03.2019 / PubMed / Full text
Intensified mitophagy in skeletal muscle with aging is downregulated by PGC-1alpha overexpression in vivo. / 01.2019 / PubMed / Full text
Melatonin protects chronic kidney disease mesenchymal stem cells against senescence via PrP -dependent enhancement of the mitochondrial function. / 01.2019 / PubMed / Full text
PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. / 03.2019 / PubMed / Full text
Grape skin extract improves muscle function and extends lifespan of a Drosophila model of Parkinson's disease through activation of mitophagy. / 11.2018 / PubMed / Full text
Imaging mitophagy in the fruit fly. / 2018 / PubMed / Full text
Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease. / 2018 / PubMed / Full text
PINK1 protects against oxidative stress induced senescence of human nucleus pulposus cells via regulating mitophagy. / 02.10.2018 / PubMed / Full text
Deficiency of parkin and PINK1 impairs age-dependent mitophagy in [i]Drosophila[/i]. / 29.05.2018 / PubMed / Full text
ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. / 04.2018 / PubMed / Full text
In vivo imaging reveals mitophagy independence in the maintenance of axonal mitochondria during normal aging. / 10.2017 / PubMed / Full text
Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. / 02.08.2017 / PubMed / Full text
The age-associated loss of ischemic preconditioning in the kidney is accompanied by mitochondrial dysfunction, increased protein acetylation and decreased autophagy. / 15.03.2017 / PubMed / Full text
Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging. / 26.02.2017 / PubMed / Full text
PINK1 signaling in mitochondrial homeostasis and in aging (Review). / 01.2017 / PubMed / Full text
Involvement of PINK1/Parkin-mediated mitophagy in AGE-induced cardiomyocyte aging. / 15.01.2017 / PubMed / Full text
Identifying potential PARIS homologs in D. melanogaster. / 03.11.2016 / PubMed / Full text
Restoring Pharmacologic Preconditioning in the Aging Heart: Role of Mitophagy/Autophagy. / 01.04.2017 / PubMed / Full text
HSP27 Alleviates Cardiac Aging in Mice via a Mechanism Involving Antioxidation and Mitophagy Activation. / 2016 / PubMed / Full text
Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan. / 12.04.2016 / PubMed / Full text
Interfacing mitochondrial biogenesis and elimination to enhance host pathogen defense and longevity. / 07-09.2015 / PubMed / Full text
Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1. / 10.2015 / PubMed / Full text
Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain. / 27.05.2015 / PubMed / Full text
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis. / 02.2015 / PubMed / Full text
The degeneration and replacement of dopamine cells in Parkinson's disease: the role of aging. / 2014 / PubMed / Full text
Defective mitophagy in XPA via PARP-1 hyperactivation and NAD( )/SIRT1 reduction. / 08.05.2014 / PubMed / Full text
Antiaging properties of a grape-derived antioxidant are regulated by mitochondrial balance of fusion and fission leading to mitophagy triggered by a signaling network of Sirt1-Sirt3-Foxo3-PINK1-PARKIN. / 2014 / PubMed / Full text
Impaired sense of smell in a Drosophila Parkinson's model. / 2013 / PubMed / Full text
Mitochondrial autophagy involving renal injury and aging is modulated by caloric intake in aged rat kidneys. / 2013 / PubMed / Full text

CD27[править]

Immunosenescence: a key player in cancer development. / 10.11.2020 / PubMed / Full text
T Lymphocytes in Patients With Nijmegen Breakage Syndrome Demonstrate Features of Exhaustion and Senescence in Flow Cytometric Evaluation of Maturation Pathway. / 2020 / PubMed / Full text
The aging common marmoset's immune system: From junior to senior. / 06.2020 / PubMed / Full text
Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection. / 07.2020 / PubMed / Full text
The Interplay between CD27 and CD27 B Cells Ensures the Flexibility, Stability, and Resilience of Human B Cell Memory. / 03.03.2020 / PubMed / Full text
CMV-independent increase in CD27-CD28 CD8 EMRA T cells is inversely related to mortality in octogenarians. / 2020 / PubMed / Full text
Compartmentalized cytotoxic immune response leads to distinct pathogenic roles of natural killer and senescent CD8 T cells in human cutaneous leishmaniasis. / 04.2020 / PubMed / Full text
CD27- IgD- B cell memory subset associates with inflammation and frailty in elderly individuals but only in males. / 2019 / PubMed / Full text
T Cell Transcriptional Profiling and Immunophenotyping Uncover LAG3 as a Potential Significant Target of Immune Modulation in Multiple Myeloma. / 01.2020 / PubMed / Full text
Are skin senescence and immunosenescence linked within individuals? / 08.2019 / PubMed / Full text
Circulating Senescent T Cells Are Linked to Systemic Inflammation and Lesion Size During Human Cutaneous Leishmaniasis. / 2018 / PubMed / Full text
Low IL-2 Expressing T Cells in Thalassemia Major Patients: Is It Immune Aging. / 10.2018 / PubMed / Full text
Senescence markers: Predictive for response to checkpoint inhibitors. / 01.03.2019 / PubMed / Full text
Features of Immunosenescence in Women Newly Diagnosed With Breast Cancer. / 2018 / PubMed / Full text
Age, calorie restriction, and age of calorie restriction onset reduce maturation of natural killer cells in C57Bl/6 mice. / 07.2018 / PubMed / Full text
CD57 identifies T cells with functional senescence before terminal differentiation and relative telomere shortening in patients with activated PI3 kinase delta syndrome. / 11.2018 / PubMed / Full text
An immunological age index in bipolar disorder: A confirmatory factor analysis of putative immunosenescence markers and associations with clinical characteristics. / 12.2018 / PubMed / Full text
Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood. / 06.2018 / PubMed / Full text
Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low PAX5. / 08.2018 / PubMed / Full text
Dynamics of CD4 and CD8 T-Cell Subsets and Inflammatory Biomarkers during Early and Chronic HIV Infection in Mozambican Adults. / 2017 / PubMed / Full text
Genetic influence on splenic natural killer cell frequencies and maturation among aged mice. / 04.2018 / PubMed / Full text
Increased senescent CD8 T cells in the peripheral blood mononuclear cells of Behçet's disease patients. / 03.2018 / PubMed / Full text
T-cell differentiation and CD56 levels in polypoidal choroidal vasculopathy and neovascular age-related macular degeneration. / 20.11.2017 / PubMed / Full text
Human CD8 EMRA T cells display a senescence-associated secretory phenotype regulated by p38 MAPK. / 02.2018 / PubMed / Full text
Human IgG2- and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age. / 10.2017 / PubMed / Full text
Impact of age and cytomegalovirus on CD8 T-cell compartment remodeling after solid organ transplantation: A one-year follow-up study. / 09.2017 / PubMed / Full text
Lymph node and circulating T cell characteristics are strongly correlated in end-stage renal disease patients, but highly differentiated T cells reside within the circulation. / 05.2017 / PubMed / Full text
Calorie Restriction Attenuates Terminal Differentiation of Immune Cells. / 2016 / PubMed / Full text
Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia. / 05.01.2017 / PubMed / Full text
Phenotypic characteristics of aged CD4 CD28 T lymphocytes are determined by changes in the whole-genome DNA methylation pattern. / 04.2017 / PubMed / Full text
Age-Associated B Cells with Proinflammatory Characteristics Are Expanded in a Proportion of Multiple Sclerosis Patients. / 15.12.2016 / PubMed / Full text
Specific phenotype and function of CD56-expressing innate immune cell subsets in human thymus. / 12.2016 / PubMed / Full text
Inflammatory and immune markers associated with physical frailty syndrome: findings from Singapore longitudinal aging studies. / 17.05.2016 / PubMed / Full text
Alteration of T Cell Subtypes in Beta-Thalassaemia Major: Impact of Ferritin Level. / 02.2016 / PubMed / Full text
Genetic Influence on the Peripheral Blood CD4 T-cell Differentiation Status in CMV Infection. / 12.2016 / PubMed / Full text
Age-related profiling of DNA methylation in CD8 T cells reveals changes in immune response and transcriptional regulator genes. / 19.08.2015 / PubMed / Full text
Senescent profile of angiogenic T cells from systemic lupus erythematosus patients. / 03.2016 / PubMed / Full text
Age-related aspects of human IgM( ) B cell heterogeneity. / 12.2015 / PubMed / Full text
Multifunctional cytomegalovirus (CMV)-specific CD8( ) T cells are not restricted by telomere-related senescence in young or old adults. / 04.2015 / PubMed / Full text
The CD27 memory B cells display changes in the gene expression pattern in elderly individuals. / 06.09.2014 / PubMed / Full text
γ/δ T cell subsets in human aging using the classical α/β T cell model. / 10.2014 / PubMed / Full text
Double negative (CD19 IgG IgD-CD27-) B lymphocytes: a new insight from telomerase in healthy elderly, in centenarian offspring and in Alzheimer's disease patients. / 11.2014 / PubMed / Full text
Impact of HIV on CD8 T cell CD57 expression is distinct from that of CMV and aging. / 2014 / PubMed / Full text
Decreased proportion of cytomegalovirus specific CD8 T-cells but no signs of general immunosenescence in Alzheimer's disease. / 2013 / PubMed / Full text

FEV[править]

Prediction of Lung Function in Adolescence Using Epigenetic Aging: A Machine Learning Approach. / 09.11.2020 / PubMed / Full text
Effect of Age on the Efficacy and Safety of Once-Daily Single-Inhaler Triple Therapy Fluticasone Furoate/Umeclidinium/Vilanterol in Patients With Chronic Obstructive Pulmonary Disease: A Post Hoc Analysis of the IMPACT Trial. / 05.10.2020 / PubMed / Full text
A comprehensive analysis of factors related to lung function in older adults: Cross-sectional findings from the Canadian Longitudinal Study on Aging. / 11.2020 / PubMed / Full text
Cigarette smoke induction of S100A9 contributes to chronic obstructive pulmonary disease. / 23.09.2020 / PubMed / Full text
Risk factors associated with the detection of pulmonary emphysema in older asymptomatic respiratory subjects. / 09.06.2020 / PubMed / Full text
Tiotropium Respimat Efficacy and Safety in Asthma: Relationship to Age. / 09.2020 / PubMed / Full text
Current Bronchodilator Responsiveness Criteria Underestimate Asthma in Older Adults. / 08.2020 / PubMed / Full text
Physical performances show conflicting associations in aged manual workers. / 10.02.2020 / PubMed / Full text
FEV as a Standalone Spirometric Predictor and the Attributable Fraction for Death in Older Persons. / 02.2020 / PubMed / Full text
An Individualized Prediction Model for Long-term Lung Function Trajectory and Risk of COPD in the General Population. / 03.2020 / PubMed / Full text
Telomere length and lung function in a population-based cohort of children and mid-life adults. / 12.2019 / PubMed / Full text
Rate of normal lung function decline in ageing adults: a systematic review of prospective cohort studies. / 27.06.2019 / PubMed / Full text
The moderating effect of childhood disadvantage on the associations between smoking and occupational exposure and lung function; a cross sectional analysis of the UK Household Longitudinal Study (UKHLS). / 04.06.2019 / PubMed / Full text
Occupational exposure to solvents and lung function decline: A population based study. / 07.2019 / PubMed / Full text
Disease-Specific Comorbidity Clusters in COPD and Accelerated Aging. / 14.04.2019 / PubMed / Full text
The Effect of the Stretch-Shortening Cycle in the Force-Velocity Relationship and Its Association With Physical Function in Older Adults With COPD. / 2019 / PubMed / Full text
Socioeconomic status and pulmonary function, transition from childhood to adulthood: cross-sectional results from the polish part of the HAPIEE study. / 09.01.2019 / PubMed / Full text
Benefits of improved air quality on ageing lungs: impacts of genetics and obesity. / 04.2019 / PubMed / Full text
The Effects of Aging on Exhaled Nitric Oxide (FeNO) in a North African Population. / 02.2019 / PubMed / Full text
Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS). / 02.2019 / PubMed / Full text
Metastable DNA methylation sites associated with longitudinal lung function decline and aging in humans: an epigenome-wide study in the NAS and KORA cohorts. / 2018 / PubMed / Full text
Contribution of peripheral airway function to changes in FEV /FVC and RV/TLC with aging. / 01.11.2018 / PubMed / Full text
Movement behaviours are associated with lung function in middle-aged and older adults: a cross-sectional analysis of the Canadian longitudinal study on aging. / 03.07.2018 / PubMed / Full text
Relationship between pulmonary function and peripheral vascular function in older Chinese: Guangzhou biobank cohort study-CVD. / 21.05.2018 / PubMed / Full text
The role of air pollution and lung function in cognitive impairment. / 02.2018 / PubMed / Full text
Heterogeneous pattern of differences in respiratory parameters between elderly with either good or poor FEV . / 06.02.2018 / PubMed / Full text
Longitudinal assessment of lung function in extremely prematurely born children. / 03.2018 / PubMed / Full text
Older women exhibit greater airway 8-isoprostane responses to strenuous exercise compared with older men and younger controls. / 05.2018 / PubMed / Full text
The association between leisure-time physical activity and lung function in older adults: The English longitudinal study of ageing. / 01.2018 / PubMed / Full text
Spirometry reference values for an andean high-altitude population. / 01.2018 / PubMed / Full text
Consumption of fruit and vegetables might mitigate the adverse effects of ambient PM on lung function among adults. / 01.2018 / PubMed / Full text
Comparative Clinical, Physiological, and Inflammatory Characteristics of Elderly Subjects With or Without Asthma and Young Subjects With Asthma. / 12.2017 / PubMed / Full text
"Spirometric" lung age reference equations: A narrative review. / 01.2018 / PubMed / Full text
Aging and extrapulmonary effects of chronic obstructive pulmonary disease. / 2017 / PubMed / Full text
Prognostic value of short-term decline of forced expiratory volume in 1 s over height cubed (FEV /Ht ) in a cohort of adults aged 80 and over. / 05.2018 / PubMed / Full text
Relationship between lung function and grip strength in older hospitalized patients: a pilot study. / 2017 / PubMed / Full text
[The role of spirometry in encouraging smoking cessation in general practice. A pilot study using "lung age"]. / 09.2017 / PubMed / Full text
Development, Validity and Reliability of the Londrina Activities of Daily Living Protocol for Subjects With COPD. / 03.2017 / PubMed / Full text
Airway wall thickness on HRCT scans decreases with age and increases with smoking. / 01.02.2017 / PubMed / Full text
Menopause Is Associated with Accelerated Lung Function Decline. / 15.04.2017 / PubMed / Full text
Predictive Value of Different Expressions of Forced Expiratory Volume in 1 Second (FEV1) for Adverse Outcomes in a Cohort of Adults Aged 80 and Older. / 01.02.2017 / PubMed / Full text
Effect of aging on sputum inflammation and asthma control. / 06.2017 / PubMed / Full text
Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS. / 15.02.2017 / PubMed / Full text
Dyspnea in Community-Dwelling Older Persons: A Multifactorial Geriatric Health Condition. / 10.2016 / PubMed / Full text

MIP[править]

Inspiratory muscle training improves cerebrovascular and postural control responses during orthostatic stress in older women. / 10.2020 / PubMed / Full text
A novel multi-marker discovery approach identifies new serum biomarkers for Parkinson's disease in older people: an EXosomes in PArkiNson Disease (EXPAND) ancillary study. / 10.2020 / PubMed / Full text
Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning. / 08.2020 / PubMed / Full text
Activation of epidermal growth factor receptor signaling mediates cellular senescence induced by certain pro-inflammatory cytokines. / 05.2020 / PubMed / Full text
Comparison of balance changes after inspiratory muscle or Otago exercise training. / 2020 / PubMed / Full text
[i]Lactobacillus acidophilus[/i] DDS-1 Modulates Intestinal-Specific Microbiota, Short-Chain Fatty Acid and Immunological Profiles in Aging Mice. / 07.06.2019 / PubMed / Full text
Systemic inflammation contributes to impairment of quality of life in chronic pancreatitis. / 13.05.2019 / PubMed / Full text
Open Mouth-Maximal Isometric Press: Development and Norms for Clinical Swallowing Evaluations and Treatment. / 21.02.2019 / PubMed / Full text
A New Understanding of the Role of IL-1 in Age-Related Intervertebral Disc Degeneration in a Murine Model. / 08.2019 / PubMed / Full text
Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis. / 27.02.2019 / PubMed / Full text
Inflammation and Monocyte Recruitment due to Aging and Mechanical Stretch in Alveolar Epithelium are Inhibited by the Molecular Chaperone 4-phenylbutyrate. / 12.2018 / PubMed / Full text
Prophylactic Palmitoylethanolamide Prolongs Survival and Decreases Detrimental Inflammation in Aged Mice With Bacterial Meningitis. / 2018 / PubMed / Full text
Establishment of a lethal aged mouse model of human respiratory syncytial virus infection. / 01.2019 / PubMed / Full text
Mitochondrial DNA variants and pulmonary function in older persons. / 01.2019 / PubMed / Full text
Respiratory Muscle Strength as a Discriminator of Sarcopenia in Community-Dwelling Elderly: A Cross-Sectional Study. / 2018 / PubMed / Full text
The Role of Pulmonary and Systemic Immunosenescence in Acute Lung Injury. / 08.2018 / PubMed / Full text
Cortical and hippocampal expression of inflammatory and intracellular signaling proteins in aged rats submitted to aerobic and resistance physical training. / 09.2018 / PubMed / Full text
Age-Related Changes to Human Tear Composition. / 01.04.2018 / PubMed / Full text
Sex Differences in Adipose Tissue CD8 T Cells and Regulatory T Cells in Middle-Aged Mice. / 2018 / PubMed / Full text
Reaction time in healthy elderly is associated with chronic low-grade inflammation and advanced glycation end product. / 15.07.2018 / PubMed / Full text
Inspiratory muscle training improves physical performance and cardiac autonomic modulation in older women. / 06.2018 / PubMed / Full text
Cerebrospinal Fluid and Plasma Levels of Inflammation Differentially Relate to CNS Markers of Alzheimer's Disease Pathology and Neuronal Damage. / 2018 / PubMed / Full text
Skeletal Muscle Injury Biomarkers: Assay Qualification Efforts and Translation to the Clinic. / 10.2017 / PubMed / Full text
Brainstem cytokine changes in healthy ageing and Motor Neurone Disease. / 15.10.2017 / PubMed / Full text
Validity of maximum isometric tongue pressure as a screening test for physical frailty: Cross-sectional study of Japanese community-dwelling older adults. / 02.2018 / PubMed / Full text
Middle age exacerbates acute respiratory distress syndrome in a double hit murine model. / 01.10.2017 / PubMed / Full text
Evaluation of Respiratory Muscle Strength in the Acute Phase of Stroke: The Role of Aging and Anthropometric Variables. / 10.2017 / PubMed / Full text
Epstein-Barr virus latent membrane protein-1 up-regulates cytokines and correlates with older age and poorer prognosis in Hodgkin lymphoma. / 02.2017 / PubMed / Full text
The effect of sex on immune cells in healthy aging: Elderly women have more robust natural killer lymphocytes than do elderly men. / 06.2016 / PubMed / Full text
Skewing of peritoneal resident macrophages toward M1-like is involved in enhancement of inflammatory responses induced by secondary necrotic neutrophils in aged mice. / 06-07.2016 / PubMed / Full text
Acute effects of different inspiratory efforts on ventilatory pattern and chest wall compartmental distribution in elderly women. / 15.06.2016 / PubMed / Full text
Cholecystokinin expression in the β-cell leads to increased β-cell area in aged mice and protects from streptozotocin-induced diabetes and apoptosis. / 15.11.2015 / PubMed / Full text
Association of systemic inflammation with epicardial fat and coronary artery calcification. / 05.2015 / PubMed / Full text
Ovariectomy shortens the life span of female mice. / 10.05.2015 / PubMed / Full text
Postural vital capacity difference with aging in duchenne muscular dystrophy. / 11.2015 / PubMed / Full text
Attenuated phagocytosis of secondary necrotic neutrophils by macrophages in aged and SMP30 knockout mice. / 01.2016 / PubMed / Full text
Distinct age-matched serum biomarker profiles in patients with cutaneous T-cell lymphoma. / 08.2014 / PubMed / Full text
Relationship between respiratory muscle strength and physical performance in elderly hospitalized patients. / 08.2014 / PubMed / Full text
Neutrophil depletion in the early inflammatory phase delayed cutaneous wound healing in older rats: improvements due to the use of un-denatured camel whey protein. / 04.03.2014 / PubMed / Full text
Strength training and testosterone treatment have opposing effects on migration inhibitor factor levels in ageing men. / 2013 / PubMed / Full text
Age-related differences in tongue-palate pressures for strength and swallowing tasks. / 12.2013 / PubMed / Full text
Bioluminescence imaging reveals dynamics of beta cell loss in the non-obese diabetic (NOD) mouse model. / 2013 / PubMed / Full text
Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound infection with advanced age. / 15.02.2013 / PubMed / Full text
Relationship between age/gender-induced survival changes and the magnitude of inflammatory activation and organ dysfunction in post-traumatic sepsis. / 2012 / PubMed / Full text

MET[править]

Self-rated health in relation to fruit and vegetable consumption and physical activity among older cancer survivors. / 26.09.2020 / PubMed / Full text
Catalog of Lung Cancer Gene Mutations Among Chinese Patients. / 2020 / PubMed / Full text
Leisure-time physical activity volume, intensity, and duration from mid- to late-life in U.S. subpopulations by race and sex. The Atherosclerosis Risk In Communities (ARIC) Study. / 13.03.2020 / PubMed / Full text
Repressive H3K9me2 protects lifespan against the transgenerational burden of COMPASS activity in [i]C. elegans[/i]. / 09.12.2019 / PubMed / Full text
Light-Intensity Physical Activity in a Large Prospective Cohort of Older US Adults: A 21-Year Follow-Up of Mortality. / 2020 / PubMed / Full text
Influence of Anthropometrics on Step-Rate Thresholds for Moderate and Vigorous Physical Activity in Older Adults: Scientific Modeling Study. / 13.12.2018 / PubMed / Full text
Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study. / 12.06.2019 / PubMed / Full text
Metformin prevents murine ovarian aging. / 10.06.2019 / PubMed / Full text
Afterword: Oral Methioninase-Answer to Cancer and Fountain of Youth? / 2019 / PubMed / Full text
Leveraging Household Structure for Increasing Adult Physical Activity in a Low-Income, African American Community. / 07.2020 / PubMed / Full text
Appropriate Amount of Regular Exercise Is Associated with a Reduced Mortality Risk. / 12.2018 / PubMed / Full text
The Relationship between Cardiorespiratory Fitness and Montreal Cognitive Assessment Scores in Older Adults. / 2018 / PubMed / Full text
Metabolic adaptation of short-living growth hormone transgenic mice to methionine restriction and supplementation. / 04.2018 / PubMed / Full text
Does the use of outdoor fitness equipment by older adults qualify as moderate to vigorous physical activity? / 2018 / PubMed / Full text
Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text
The metabolic equivalents of one-mile walking by older adults; implications for health promotion. / 2017 / PubMed / Full text
The effect of age on fitness among female firefighters. / 01.10.2017 / PubMed / Full text
Physical Activity in Midlife is not Associated with Cognitive Health in Later Life Among Cognitively Normal Older Adults. / 2017 / PubMed / Full text
Associations Between Self-Reported Physical Activity and Physical Performance Measures Over Time in Postmenopausal Women: The Women's Health Initiative. / 10.2017 / PubMed / Full text
Anti-aging pharmacology in cutaneous wound healing: effects of metformin, resveratrol, and rapamycin by local application. / 10.2017 / PubMed / Full text
Optical properties of the human lens constituents. / 08.2017 / PubMed / Full text
High intensity interval training (HIIT) improves resting blood pressure, metabolic (MET) capacity and heart rate reserve without compromising cardiac function in sedentary aging men. / 08.2018 / PubMed / Full text
Relationship Between Lifelong Exercise Volume and Coronary Atherosclerosis in Athletes. / 11.07.2017 / PubMed / Full text
Physical activity and telomere length in U.S. men and women: An NHANES investigation. / 07.2017 / PubMed / Full text
Glycation inhibitors extend yeast chronological lifespan by reducing advanced glycation end products and by back regulation of proteins involved in mitochondrial respiration. / 06.03.2017 / PubMed / Full text
Testing a Matching Hypothesis for Emerging Adults in Project MATCH: During-Treatment and One-Year Outcomes. / 01.2017 / PubMed / Full text
Non-sedentary Lifestyle Can Reduce Hip Fracture Risk among Older Caucasians Adults: The Adventist Health Study-2. / 2015 / PubMed / Full text
Performance of Older Persons in a Simulated Shopping Task Is Influenced by Priming with Age Stereotypes. / 2016 / PubMed / Full text
Metabolic Equivalent in Adolescents, Active Adults and Pregnant Women. / 20.07.2016 / PubMed / Full text
Motor effort training with low exercise intensity improves muscle strength and descending command in aging. / 06.2016 / PubMed / Full text
Changes in Neural Connectivity and Memory Following a Yoga Intervention for Older Adults: A Pilot Study. / 2016 / PubMed / Full text
Changes in physical activity during transition to retirement: a cohort study. / 16.04.2016 / PubMed / Full text
Accuracy of Direct Observation to Assess Physical Activity in Older Adults. / 10.2016 / PubMed / Full text
Multimorbidity, cognitive function, and physical activity. / 02.2016 / PubMed / Full text
Age-dependent prognostic value of exercise capacity and derivation of fitness-associated biologic age. / 03.2016 / PubMed / Full text
Elderly men with moderate and intense training lifestyle present sustained higher antibody responses to influenza vaccine. / 12.2015 / PubMed / Full text
Altered dietary methionine differentially impacts glutathione and methionine metabolism in long-living growth hormone-deficient Ames dwarf and wild-type mice. / 2014 / PubMed / Full text
Diabetes-related distress, insulin dose, and age contribute to insulin-associated weight gain in patients with type 2 diabetes: results of a prospective study. / 10.2014 / PubMed / Full text
A prospective epigenetic paradigm between cellular senescence and epithelial-mesenchymal transition in organismal development and aging. / 01.2015 / PubMed / Full text
Associations of physical exercise as a lifestyle habit with lean and fat body mass and handgrip strength and age in Asian men. / 09.2014 / PubMed / Full text
Exercise capacity and all-cause mortality in male veterans with hypertension aged ≥70 years. / 07.2014 / PubMed / Full text
Physical activity and mortality in a prospective cohort of middle-aged and elderly men - a time perspective. / 08.08.2013 / PubMed / Full text
Years of life gained due to leisure-time physical activity in the U.S. / 01.2013 / PubMed / Full text

FGF21[править]

Differential effects of sulfur amino acid-restricted and low-calorie diets on gut microbiome profile and bile acid composition in male C57BL6/J mice. / 27.10.2020 / PubMed / Full text
Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging. / 31.10.2020 / PubMed / Full text
Alignment of Alzheimer's disease amyloid β-peptide and klotho. / 11-12.2020 / PubMed / Full text
Relationship between physical activity and circulating fibroblast growth factor 21 in middle-aged and older adults. / 11.2020 / PubMed / Full text
Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy. / 09.2020 / PubMed / Full text
Mitochondria, immunosenescence and inflammaging: a role for mitokines? / 10.2020 / PubMed / Full text
Age-at-onset-dependent effects of sulfur amino acid restriction on markers of growth and stress in male F344 rats. / 07.2020 / PubMed / Full text
Fibroblast growth factor 21 prolongs lifespan and improves stress tolerance in the silkworm, [i]Bombyx mori[/i]. / 03.2020 / PubMed / Full text
Myokines as biomarkers of frailty and cardiovascular disease risk in females. / 05.2020 / PubMed / Full text
Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice. / 13.11.2019 / PubMed / Full text
Fibroblast Growth Factor 21 Mediates the Associations between Exercise, Aging, and Glucose Regulation. / 02.2020 / PubMed / Full text
Effects of Moderate Chronic Food Restriction on the Development of Postprandial Dyslipidemia with Ageing. / 10.08.2019 / PubMed / Full text
Inhibition of the Fission Machinery Mitigates OPA1 Impairment in Adult Skeletal Muscles. / 15.06.2019 / PubMed / Full text
Higher serum levels of fibroblast growth factor 21 in old patients with cachexia. / 07-08.2019 / PubMed / Full text
Impact of aging and caloric restriction on fibroblast growth factor 21 signaling in rat white adipose tissue. / 04.2019 / PubMed / Full text
Kotho and aging. / 09.2016 / PubMed
The Klotho proteins in health and disease. / 01.2019 / PubMed / Full text
Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue. / 10.2018 / PubMed / Full text
Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. / 12.2019 / PubMed / Full text
Human Aging and Longevity Are Characterized by High Levels of Mitokines. / 23.04.2019 / PubMed / Full text
[Fibroblast growth factor-21 as a marker of premature aging in young and middled-aged men with type 2 diabetes]. / 03.2018 / PubMed
Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through SIRT1. / 2017 / PubMed / Full text
Integrated stress response stimulates FGF21 expression: Systemic enhancer of longevity. / 12.2017 / PubMed / Full text
Fibroblast growth factor 21: a regulator of metabolic disease and health span. / 01.09.2017 / PubMed / Full text
Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence. / 06.06.2017 / PubMed / Full text
Regulation of longevity by FGF21: Interaction between energy metabolism and stress responses. / 08.2017 / PubMed / Full text
FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process. / 02.2017 / PubMed / Full text
Methionine restriction improves renal insulin signalling in aged kidneys. / 07.2016 / PubMed / Full text
FGF21 represses cerebrovascular aging via improving mitochondrial biogenesis and inhibiting p53 signaling pathway in an AMPK-dependent manner. / 15.08.2016 / PubMed / Full text
Role of mitochondrial function in cell death and body metabolism. / 01.06.2016 / PubMed / Full text
Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution. / 26.01.2016 / PubMed / Full text
Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice. / 15.01.2016 / PubMed / Full text
Effect of mitochondrial stress on systemic metabolism. / 09.2015 / PubMed / Full text
Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity. / 03.08.2015 / PubMed / Full text
Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individuals. / 01.06.2015 / PubMed / Full text
A preliminary candidate approach identifies the combination of chemerin, fetuin-A, and fibroblast growth factors 19 and 21 as a potential biomarker panel of successful aging. / 06.2015 / PubMed / Full text
Fibroblast growth factor 21 protects mouse brain against D-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation. / 06.2015 / PubMed / Full text
Cardiorespiratory fitness and visceral fat are key determinants of serum fibroblast growth factor 21 concentration in Japanese men. / 10.2014 / PubMed / Full text
Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21. / 10.2014 / PubMed / Full text
High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: involvement of peroxisome proliferator-activated receptor γ signaling. / 11.2013 / PubMed / Full text

PSD[править]

Cotinine ameliorates memory and learning impairment in senescent mice. / 11.2020 / PubMed / Full text
Quantitative Immunoblotting Analyses Reveal that the Abundance of Actin, Tubulin, Synaptophysin and EEA1 Proteins is Altered in the Brains of Aged Mice. / 21.08.2020 / PubMed / Full text
Exercise Attenuates Brain Aging by Rescuing Down-Regulated Wnt/β-Catenin Signaling in Aged Rats. / 2020 / PubMed / Full text
Concurrent nicotine exposure to prenatal alcohol consumption alters the hippocampal and cortical neurotoxicity. / 01.2020 / PubMed / Full text
The Experience of Family Physicians and Home Health Staff Involved in an Intervention to Increase Patient-Related Collaboration. / 12.2019 / PubMed / Full text
Pterostilbene Improves Cognitive Performance in Aged Rats: An in Vivo Study. / 2019 / PubMed / Full text
Higher Levels of Protein Palmitoylation in the Frontal Cortex across Aging Were Associated with Reference Memory and Executive Function Declines. / 01-02.2019 / PubMed / Full text
A single cocaine administration alters dendritic spine morphology and impairs glutamate receptor synaptic retention in the medial prefrontal cortex of adolescent rats. / 15.09.2018 / PubMed / Full text
Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning. / 02.2019 / PubMed / Full text
Dynamic SAP102 expression in the hippocampal subregions of rats and APP/PS1 mice of various ages. / 06.2018 / PubMed / Full text
Downregulated Nuclear Factor E2-Related Factor 2 (Nrf2) Aggravates Cognitive Impairments via Neuroinflammation and Synaptic Plasticity in the Senescence-Accelerated Mouse Prone 8 (SAMP8) Mouse: A Model of Accelerated Senescence. / 23.02.2018 / PubMed / Full text
Development of Glutamatergic Proteins in Human Visual Cortex across the Lifespan. / 21.06.2017 / PubMed / Full text
Spinal and corticospinal pathways are differently modulated when standing at the bottom and the top of a three-step staircase in young and older adults. / 06.2017 / PubMed / Full text
Aging alters the molecular dynamics of synapses in a sexually dimorphic pattern in zebrafish (Danio rerio). / 06.2017 / PubMed / Full text
Subacute ibuprofen treatment rescues the synaptic and cognitive deficits in advanced-aged mice. / 05.2017 / PubMed / Full text
Strength and Aerobic Exercises Improve Spatial Memory in Aging Rats Through Stimulating Distinct Neuroplasticity Mechanisms. / 12.2017 / PubMed / Full text
Age-Associated Changes in the Spectral and Statistical Parameters of Surface Electromyogram of Tibialis Anterior. / 2016 / PubMed / Full text
Diverse Synaptic Distributions of G Protein-coupled Estrogen Receptor 1 in Monkey Prefrontal Cortex with Aging and Menopause. / 01.03.2017 / PubMed / Full text
BDNF pathway is involved in the protective effects of SS-31 on isoflurane-induced cognitive deficits in aging mice. / 15.05.2016 / PubMed / Full text
Multiplex analyte assays to characterize different dementias: brain inflammatory cytokines in poststroke and other dementias. / 02.2016 / PubMed / Full text
Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression. / 12.01.2016 / PubMed / Full text
Adaptive Plasticity in the Hippocampus of Young Mice Intermittently Exposed to MDMA Could Be the Origin of Memory Deficits. / 12.2016 / PubMed / Full text
Lactational exposure of mice to low levels of non-dioxin-like polychlorinated biphenyls increases susceptibility to neuronal stress at a mature age. / 03.2016 / PubMed / Full text
Selective Brain-Targeted Antagonism of p38 MAPKα Reduces Hippocampal IL-1β Levels and Improves Morris Water Maze Performance in Aged Rats. / 2015 / PubMed / Full text
Partial sleep deprivation activates the DNA damage response (DDR) and the senescence-associated secretory phenotype (SASP) in aged adult humans. / 01.2016 / PubMed / Full text
Paradoxical sleep deprivation impairs mouse survival after infection with malaria parasites. / 28.04.2015 / PubMed / Full text
Adolescent intermittent alcohol exposure: persistence of structural and functional hippocampal abnormalities into adulthood. / 06.2015 / PubMed / Full text
Minocycline enhances hippocampal memory, neuroplasticity and synapse-associated proteins in aged C57 BL/6 mice. / 05.2015 / PubMed / Full text
Cardiac autonomic changes in middle-aged women: identification based on principal component analysis. / 07.2016 / PubMed / Full text
Tau-mediated NMDA receptor impairment underlies dysfunction of a selectively vulnerable network in a mouse model of frontotemporal dementia. / 03.12.2014 / PubMed / Full text
Post-stroke depression and the aging brain. / 2013 / PubMed / Full text
A framework to understand the variations of PSD-95 expression in brain aging and in Alzheimer's disease. / 11.2014 / PubMed / Full text
The effects of aging on the BTBR mouse model of autism spectrum disorder. / 2014 / PubMed / Full text
Repetitive transcranial magnetic stimulation (rTMS) influences spatial cognition and modulates hippocampal structural synaptic plasticity in aging mice. / 10.2014 / PubMed / Full text
Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease. / 01.09.2014 / PubMed / Full text
Neuron volumes in hippocampal subfields in delayed poststroke and aging-related dementias. / 04.2014 / PubMed / Full text
Communicative responses to the painful self-disclosures of familial and non-familial older adults. / 2013 / PubMed / Full text
An increase in the association of GluN2B containing NMDA receptors with membrane scaffolding proteins was related to memory declines during aging. / 24.07.2013 / PubMed / Full text
The influence of aging on poststroke depression using a rat model via middle cerebral artery occlusion. / 12.2013 / PubMed / Full text
Calcium channel-dependent molecular maturation of photoreceptor synapses. / 2013 / PubMed / Full text
Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice. / 26.12.2012 / PubMed / Full text

Aging genes 40-49

HP[править]

PCNA[править]

TF[править]

ABR[править]

CD34[править]

EGF[править]

CD44[править]

NGF[править]

PINK1[править]

CD27[править]

FEV[править]

MIP[править]

MET[править]

FGF21[править]

PSD[править]

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