Публикации о генах и старении (freqs-titles)

CD4

• Identification of Key Genes and Potential New Biomarkers for Ovarian Aging: A Study Based on RNA-Sequencing Data. / 2020 / PubMed / Full text
• Distinct Age-Related Epigenetic Signatures in CD4 and CD8 T Cells. / 2020 / PubMed / Full text
• IL-1β-MyD88-mTOR Axis Promotes Immune-Protective IL-17A Foxp3 Cells During Mucosal Infection and Is Dysregulated With Aging. / 2020 / PubMed / Full text
• Thymus involution sets the clock of declined immunity and repair with aging. / 25.11.2020 / PubMed / Full text
• Food insecurity and T-cell dysregulation in women living with HIV on antiretroviral therapy. / 28.11.2020 / PubMed / Full text
• Rapamycin Eyedrops Increased CD4 Foxp3 Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface. / 24.11.2020 / PubMed / Full text
• Antioxidants N-Acetylcysteine and Vitamin C Improve T Cell Commitment to Memory and Long-Term Maintenance of Immunological Memory in Old Mice. / 19.11.2020 / PubMed / Full text
• Evolution of comorbidities in people living with HIV between 2004 and 2014: cross-sectional analyses from ANRS CO3 Aquitaine cohort. / 16.11.2020 / PubMed / Full text
• Impact of age on CD4 recovery and viral suppression over time among adults living with HIV who initiated antiretroviral therapy in the African Cohort Study. / 12.11.2020 / PubMed / Full text
• hPMSCs protects against D-galactose-induced oxidative damage of CD4 T cells through activating Akt-mediated Nrf2 antioxidant signaling. / 04.11.2020 / PubMed / Full text
• Substantial gap in primary care: older adults with HIV presenting late to care. / 31.10.2020 / PubMed / Full text
• Quantitative Digitography Measures Fine Motor Disturbances in Chronically Treated HIV Similar to Parkinson's Disease. / 2020 / PubMed / Full text
• Monocyte and T Cell Immune Phenotypic Profiles Associated With Age Advancement Differ Between People With HIV, Lifestyle-Comparable Controls and Blood Donors. / 2020 / PubMed / Full text
• HIV and three dimensions of Wisdom: Association with cognitive function and physical and mental well-being: For: Psychiatry Research. / 12.2020 / PubMed / Full text
• CD8 T cells are present at low levels in the white matter with physiological and pathological aging. / 13.10.2020 / PubMed / Full text
• Immunotherapy in older patients with cancer. / 26.07.2020 / PubMed / Full text
• Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence. / 11.2020 / PubMed / Full text
• Conventional Treatment for Multiple Myeloma Drives Premature Aging Phenotypes and Metabolic Dysfunction in T Cells. / 2020 / PubMed / Full text
• Immunosenescence: the role of age in multiple sclerosis. / 19.09.2020 / PubMed / Full text
• Umbilical cord mesenchymal stem cells protect thymus structure and function in aged C57 mice by downregulating aging-related genes and upregulating autophagy- and anti-oxidative stress-related genes. / 14.09.2020 / PubMed / Full text
• Impaired Cytotoxic CD8 T Cell Response in Elderly COVID-19 Patients. / 18.09.2020 / PubMed / Full text
• What are the roles of antibodies versus a durable, high quality T-cell response in protective immunity against SARS-CoV-2? / 11.12.2020 / PubMed / Full text
• Per2 Upregulation in Circulating Hematopoietic Progenitor Cells During Chronic HIV Infection. / 2020 / PubMed / Full text
• COVID-19: age, Interleukin-6, C-reactive protein, and lymphocytes as key clues from a multicentre retrospective study. / 2020 / PubMed / Full text
• Immunosenescence profiles are not associated with muscle strength, physical performance and sarcopenia risk in very old adults: The Newcastle 85+ Study. / 09.2020 / PubMed / Full text
• Homeostasis and the functional roles of CD4 Treg cells in aging. / 10.2020 / PubMed / Full text
• A Comprehensive Evaluation of the Impact of Bovine Milk Containing Different Beta-Casein Profiles on Gut Health of Ageing Mice. / 19.07.2020 / PubMed / Full text
• Premature aging of circulating T cells predicts all-cause mortality in hemodialysis patients. / 13.07.2020 / PubMed / Full text
• In-depth immune cellular profiling reveals sex-specific associations with frailty. / 2020 / PubMed / Full text
• CD70 contributes to age-associated T cell defects and overwhelming inflammatory responses. / 19.06.2020 / PubMed / Full text
• Comparison of Overall and Comorbidity-Free Life Expectancy Between Insured Adults With and Without HIV Infection, 2000-2016. / 01.06.2020 / PubMed / Full text
• Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model. / 11.06.2020 / PubMed / Full text
• Thymus aging in mice deficient in either EphB2 or EphB3, two master regulators of thymic epithelium development. / 10.2020 / PubMed / Full text
• CD8 T-cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with PARN and DKC1 mutations. / 09.2020 / PubMed / Full text
• Short-Term Environmental Enrichment is a Stronger Modulator of Brain Glial Cells and Cervical Lymph Node T Cell Subtypes than Exercise or Combined Exercise and Enrichment. / 25.05.2020 / PubMed / Full text
• Viral and host factors related to the clinical outcome of COVID-19. / 07.2020 / PubMed / Full text
• Use of comedications and potential drug-drug interactions in people living with HIV in China. / 07.2020 / PubMed / Full text
• CD4 T helper 17 cell response of aged mice promotes prostate cancer cell migration and invasion. / 07.2020 / PubMed / Full text
• The Rules of Human T Cell Fate [i]in vivo[/i]. / 2020 / PubMed / Full text
• CD4/CD8 ratio, comorbidities, and aging in treated HIV infected individuals on viral suppression. / 21.04.2020 / PubMed / Full text
• The effects of advanced maternal age on T-cell subsets at the maternal-fetal interface prior to term labor and in the offspring: a mouse study. / 07.2020 / PubMed / Full text
• Structural and Functional Changes in the Mesenteric Lymph Nodes in Humans during Aging. / 03.2020 / PubMed / Full text
• Neurocognitive Functioning is Associated with Self-Reported and Performance-Based Treatment Management Abilities in People Living with HIV with Low Health Literacy. / 24.07.2020 / PubMed / Full text
• Blockade of Stat3 oncogene addiction induces cellular senescence and reveals a cell-nonautonomous activity suitable for cancer immunotherapy. / 2020 / PubMed / Full text
• Age-related changes in T lymphocytes of patients with head and neck squamous cell carcinoma. / 2020 / PubMed / Full text
• Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway. / 10.02.2020 / PubMed / Full text
• Estimating HIV Management and Comorbidity Costs Among Aging HIV Patients in the United States: A Systematic Review. / 02.2020 / PubMed / Full text
• Sex Differences in People Aging With HIV. / 01.03.2020 / PubMed / Full text
• Identification of Differentially Expressed miRNAs in the Response of Spleen CD4 T Cells to Electroacupuncture in Senescence-Accelerated Mice. / 03.2020 / PubMed / Full text
• Thymus Involution and Intravenous Drug Abuse. / 03.2020 / PubMed / Full text
• Depletion of CD4 T cells provides therapeutic benefits in aged mice after ischemic stroke. / 04.2020 / PubMed / Full text
• Immunological and Virological Responses in Older HIV-Infected Adults Receiving Antiretroviral Therapy: An Evidence-Based Meta-Analysis. / 01.04.2020 / PubMed / Full text
• African Mitochondrial DNA Haplogroup L2 Is Associated With Slower Decline of β-cell Function and Lower Incidence of Diabetes Mellitus in Non-Hispanic, Black Women Living With Human Immunodeficiency Virus. / 05.11.2020 / PubMed / Full text
• DP1 Activation Reverses Age-Related Hypertension Via NEDD4L-Mediated T-Bet Degradation in T Cells. / 25.02.2020 / PubMed / Full text
• An Emerging Concern-High Rates of Frailty among Middle-aged and Older Individuals Living with HIV. / 12.2019 / PubMed / Full text
• Higher Acuity Resource Utilization With Older Age and Poorer HIV Control in Adolescents and Young Adults in the HIV Research Network. / 01.04.2020 / PubMed / Full text
• Mitochondrial DNA Haplogroups and Frailty in Adults Living with HIV. / 03.2020 / PubMed / Full text
• Gallic acid attenuates thymic involution in the d-galactose induced accelerated aging mice. / 01.2020 / PubMed / Full text
• Mitochondrial mass governs the extent of human T cell senescence. / 02.2020 / PubMed / Full text
• T cells and immune functions of plasma extracellular vesicles are differentially modulated from adults to centenarians. / 27.11.2019 / PubMed / Full text
• Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency. / 19.11.2019 / PubMed / Full text
• Increased Prevalence of Neurocognitive Impairment in Aging People Living With Human Immunodeficiency Virus: The ANRS EP58 HAND 55-70 Study. / 10.06.2020 / PubMed / Full text
• Age-associated changes in human CD4 T cells point to mitochondrial dysfunction consequent to impaired autophagy. / 09.11.2019 / PubMed / Full text
• Sex Differences in the Blood Transcriptome Identify Robust Changes in Immune Cell Proportions with Aging and Influenza Infection. / 12.11.2019 / PubMed / Full text
• Going Beyond Giving Antiretroviral Therapy: Multimorbidity in Older People Aging with HIV in Nigeria. / 03.2020 / PubMed / Full text
• Alterations in composition of immune cells and impairment of anti-tumor immune response in aged oral cancer-bearing mice. / 12.2019 / PubMed / Full text
• LTA1 is a safe, intranasal enterotoxin-based adjuvant that improves vaccine protection against influenza in young, old and B-cell-depleted (μMT) mice. / 22.10.2019 / PubMed / Full text
• Thymus Imaging Detection and Size Is Inversely Associated With Metabolic Syndrome and Frailty in People With HIV. / 10.2019 / PubMed / Full text
• Alterations in peripheral T cell and B cell subsets in patients with osteoarthritis. / 02.2020 / PubMed / Full text
• Short Communication: Carotid Intima-Media Thickness Is Not Associated with Neurocognitive Impairment Among People Older than 50 Years With and Without HIV Infection from Thailand. / 11-12.2019 / PubMed / Full text
• Implications of Immune Checkpoint Expression During Aging in HIV-Infected People on Antiretroviral Therapy. / 11-12.2019 / PubMed / Full text
• Age-related alterations in human gut CD4 T cell phenotype, T helper cell frequencies, and functional responses to enteric bacteria. / 01.2020 / PubMed / Full text
• Determinants of blood telomere length in antiretroviral treatment-naïve HIV-positive participants enrolled in the NEAT 001/ANRS 143 clinical trial. / 11.2019 / PubMed / Full text
• Human T Cell Differentiation Negatively Regulates Telomerase Expression Resulting in Reduced Activation-Induced Proliferation and Survival. / 2019 / PubMed / Full text
• Short Communication: Getting Older with HIV: Increasing Frequency of Comorbidities and Polypharmacy in Brazilian HIV Patients. / 11-12.2019 / PubMed / Full text
• Gait Speed Decline Is Associated with Hemoglobin A1C, Neurocognitive Impairment, and Black Race in Persons with HIV. / 11-12.2019 / PubMed / Full text
• Noncommunicable Diseases Burden and Risk Factors in a Cohort of HIV+ Elderly Patients in Malawi. / 11-12.2019 / PubMed / Full text
• Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes. / 08.2019 / PubMed / Full text
• Prevalence of hypertension and cardiovascular risk factors among long-term AIDS survivors: A report from the field. / 10.2019 / PubMed / Full text

TNF

• Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe mice: role of SIRT1. / 18.11.2020 / PubMed / Full text
• Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism. / 06.11.2020 / PubMed / Full text
• Anti-aging effect of DL-β-hydroxybutyrate against hepatic cellular senescence induced by D-galactose or γ-irradiation via autophagic flux stimulation in male rats. / 01-02.2021 / PubMed / Full text
• Exploring the extensive crosstalk between the antagonistic cytokines- TGF-β and TNF-α in regulating cancer pathogenesis. / 03.11.2020 / PubMed / Full text
• Long non-coding RNA SNHG29 regulates cell senescence via p53/p21 signaling in spontaneous preterm birth. / 15.10.2020 / PubMed / Full text
• Cognition Is Associated With Peripheral Immune Molecules in Healthy Older Adults: A Cross-Sectional Study. / 2020 / PubMed / Full text
• Anti-aging effects of [i]Ribes meyeri[/i] anthocyanins on neural stem cells and aging mice. / 12.09.2020 / PubMed / Full text
• Effects of a four week detraining period on physical, metabolic, and inflammatory profiles of elderly women who regularly participate in a program of strength training. / 2020 / PubMed / Full text
• Contribution of Porphyromonas gingivalis lipopolysaccharide to experimental periodontitis in relation to aging. / 26.08.2020 / PubMed / Full text
• New MoDC-Targeting TNF Fusion Proteins Enhance Cyclic Di-GMP Vaccine Adjuvanticity in Middle-Aged and Aged Mice. / 2020 / PubMed / Full text
• Cognitive impairment in elderly patients with rheumatic disease and the effect of disease-modifying anti-rheumatic drugs. / 30.08.2020 / PubMed / Full text
• Cotinine ameliorates memory and learning impairment in senescent mice. / 11.2020 / PubMed / Full text
• Kynurenines link chronic inflammation to functional decline and physical frailty. / 20.08.2020 / PubMed / Full text
• Voluntary exercise training attenuated the middle-aged maturity-induced cardiac apoptosis. / 15.10.2020 / PubMed / Full text
• Preclinical Evaluation of a Food-Derived Functional Ingredient to Address Skeletal Muscle Atrophy. / 29.07.2020 / PubMed / Full text
• Childhood survivors of high-risk neuroblastoma show signs of immune recovery and not immunosenescence. / 12.2020 / PubMed / Full text
• FK506 induces lung lymphatic endothelial cell senescence and downregulates LYVE-1 expression, with associated decreased hyaluronan uptake. / 31.07.2020 / PubMed / Full text
• Late-onset hypogonadism: Reductio ad absurdum of the cardiovascular risk-benefit of testosterone replacement therapy. / 11.2020 / PubMed / Full text
• Doxorubicin generates senescent microglia that exhibit altered proteomes, higher levels of cytokine secretion, and a decreased ability to internalize amyloid β. / 15.10.2020 / PubMed / Full text
• Time restricted feeding provides a viable alternative to alternate day fasting when evaluated in terms of redox homeostasis in rats. / 16.07.2020 / PubMed / Full text
• Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy. / 2020 / PubMed / Full text
• Chrysin Impact on Oxidative and Inflammation Damages in the Liver of Aged Male Rats. / 17.07.2020 / PubMed / Full text
• Correction of immunosuppression in aged septic rats by human ghrelin and growth hormone through the vagus nerve-dependent inhibition of TGF-β production. / 16.07.2020 / PubMed / Full text
• Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients. / 10.2020 / PubMed / Full text
• [i]Andrographis paniculata[/i] and Its Bioactive Diterpenoids Against Inflammation and Oxidative Stress in Keratinocytes. / 17.06.2020 / PubMed / Full text
• Etanercept improves aging-induced cognitive deficits by reducing inflammation and vascular dysfunction in rats. / 01.10.2020 / PubMed / Full text
• Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients. / 09.2020 / PubMed / Full text
• Bone marrow mesenchymal stem cells improve thymus and spleen function of aging rats through affecting P21/PCNA and suppressing oxidative stress. / 19.06.2020 / PubMed / Full text
• Glycolic acid adjusted to pH 4 stimulates collagen production and epidermal renewal without affecting levels of proinflammatory TNF-alpha in human skin explants. / 24.06.2020 / PubMed / Full text
• A20 of nucleus pulposus cells plays a self-protection role via the nuclear factor-kappa B pathway in the inflammatory microenvironment. / 05.2020 / PubMed / Full text
• Age-associated decline in neural, endocrine, and immune responses in men and women: Involvement of intracellular signaling pathways. / 15.08.2020 / PubMed / Full text
• Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults. / 2020 / PubMed / Full text
• Activation of FoxO1/SIRT1/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis. / 12.06.2020 / PubMed / Full text
• The senescence-associated secretome as an indicator of age and medical risk. / 18.06.2020 / PubMed / Full text
• Exercise Partially Rejuvenates Muscle Stem Cells. / 06.2020 / PubMed / Full text
• Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress. / 08.2020 / PubMed / Full text
• Potential therapeutic effects of endothelial cells trans-differentiated from Wharton's Jelly-derived mesenchymal stem cells on altered vascular functions in aged diabetic rat model. / 2020 / PubMed / Full text
• [Effect of fragmented sleep on postoperative cognitive function and central neuroinflammation]. / 05.05.2020 / PubMed / Full text
• Can blocking inflammation enhance immunity during aging? / 05.2020 / PubMed / Full text
• [FAS- and TNF-dependent ways participation in apoptosis mechanisms in hypotalumus in physiological and pathological aging.] / 2020 / PubMed
• Ultrasound-guided continuous thoracic paravertebral block alleviates postoperative delirium in elderly patients undergoing esophagectomy: A randomized controlled trial. / 04.2020 / PubMed / Full text
• 17β-Estradiol improves insulin signalling and insulin resistance in the aged female hearts: Role of inflammatory and anti-inflammatory cytokines. / 15.07.2020 / PubMed / Full text
• Synergistic Antitumor Efficacy of Magnetohyperthermia and Poly(lactic-co-glycolic acid)-Encapsulated Selol in Ehrlich Breast Adenocarcinoma Treatment in Elderly Swiss Mice. / 01.02.2020 / PubMed / Full text
• Pinitol suppresses TNF-α-induced chondrocyte senescence. / 19.03.2020 / PubMed / Full text
• [Aging of skin fibroblasts: genetic and epigenetic factors.] / 2019 / PubMed
• Functional and traditional training improve muscle power and reduce proinflammatory cytokines in older women: A randomized controlled trial. / 01.07.2020 / PubMed / Full text
• Associations of TNF-α -308 G>A and TNF-β 252 A>G with Physical Function and BNP-Rugao Longevity and Ageing Study. / 2020 / PubMed / Full text
• 3D TECA hydrogel reduces cellular senescence and enhances fibroblasts migration in wound healing. / 07.2018 / PubMed / Full text
• Regulatory Effect of Anwulignan on the Immune Function Through Its Antioxidation and Anti-Apoptosis in D-Galactose-Induced Aging Mice. / 2020 / PubMed / Full text
• Pretreatment Frailty Is Independently Associated With Increased Risk of Infections After Immunosuppression in Patients With Inflammatory Bowel Diseases. / 06.2020 / PubMed / Full text
• The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1. / 2020 / PubMed / Full text
• In the Absence of a TCR Signal IL-2/IL-12/18-Stimulated γδ T Cells Demonstrate Potent Anti-Tumoral Function Through Direct Killing and Senescence Induction in Cancer Cells. / 04.01.2020 / PubMed / Full text
• Aging is associated with loss of beneficial effects of estrogen on leptin responsiveness in mice fed high fat diet: Role of estrogen receptor α and cytokines. / 03.2020 / PubMed / Full text
• Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease? / 2019 / PubMed / Full text
• Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents. / 01.02.2020 / PubMed / Full text
• Oral Administration of Okara Soybean By-Product Attenuates Cognitive Impairment in a Mouse Model of Accelerated Aging. / 03.12.2019 / PubMed / Full text
• Electric vagal nerve stimulation inhibits inflammation and improves early postoperation cognitive dysfunction in aged rats. / 23.11.2019 / PubMed / Full text
• Metformin decreases LPS-induced inflammatory response in rabbit annulus fibrosus stem/progenitor cells by blocking HMGB1 release. / 26.11.2019 / PubMed / Full text
• The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro. / 11.12.2019 / PubMed / Full text
• Arsenic induces human chondrocyte senescence and accelerates rat articular cartilage aging. / 01.2020 / PubMed / Full text
• Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content. / 08.11.2019 / PubMed / Full text
• Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161-expressing cells. / 12.2019 / PubMed / Full text
• Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians. / 26.11.2019 / PubMed / Full text
• Gut microbiota combined with metabolomics reveals the metabolic profile of the normal aging process and the anti-aging effect of FuFang Zhenshu TiaoZhi(FTZ) in mice. / 01.2020 / PubMed / Full text
• Intervertebral disc ageing and degeneration: The antiapoptotic effect of oestrogen. / 01.2020 / PubMed / Full text
• MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages. / 30.01.2020 / PubMed / Full text
• Aerobic exercise modulates cytokine profile and sleep quality in elderly. / 06.2019 / PubMed / Full text
• Trehalose targets Nrf2 signal to alleviate d-galactose induced aging and improve behavioral ability. / 01.01.2020 / PubMed / Full text
• Anti-Inflammatory and Anti-Aging Evaluation of Pigment-Protein Complex Extracted from [i]Chlorella Pyrenoidosa[/i]. / 16.10.2019 / PubMed / Full text
• Inflammatory mediators and the risk of falls among older women with acute low back pain: data from Back Complaints in the Elders (BACE)-Brazil. / 03.2020 / PubMed / Full text
• Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders. / 03.10.2019 / PubMed / Full text
• Study on Metabolic Trajectory of Liver Aging and the Effect of Fufang Zhenzhu Tiaozhi on Aging Mice. / 2019 / PubMed / Full text
• Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults. / 13.07.2020 / PubMed / Full text
• Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia. / 14.09.2019 / PubMed / Full text
• Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice. / 14.08.2019 / PubMed / Full text
• Moderate hyperoxia induces senescence in developing human lung fibroblasts. / 01.11.2019 / PubMed / Full text
• Aging-related carcinoembryonic antigen-related cell adhesion molecule 1 signaling promotes vascular dysfunction. / 12.2019 / PubMed / Full text
• Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APP /PS1 Transgenic Mice. / 2019 / PubMed / Full text
• Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. / 09.2019 / PubMed / Full text

HR

• Patients with hip fracture and total hip arthroplasty surgery differ in anthropometric, but not cardiovascular screening abnormalities. / 02.12.2020 / PubMed / Full text
• Clinical Role of Lung Ultrasound for the Diagnosis and Prognosis of Coronavirus Disease Pneumonia in Elderly Patients: A Pivotal Study. / 03.12.2020 / PubMed / Full text
• The Relationship of Accelerometer-Assessed Standing Time With and Without Ambulation and Mortality: The WHI OPACH Study. / 12.10.2020 / PubMed / Full text
• Age-related myofiber atrophy in old mice is reversed by ten weeks voluntary high-resistance wheel running. / 09.11.2020 / PubMed / Full text
• Predicted Skeletal Muscle Mass and 4-Year Cardiovascular Disease Incidence in Middle-Aged and Elderly Participants of IKARIA Prospective Epidemiological Study: The Mediating Effect of Sex and Cardiometabolic Factors. / 27.10.2020 / PubMed / Full text
• Obesity is associated with early hip fracture risk in postmenopausal women: a 25-year follow-up. / 23.10.2020 / PubMed / Full text
• ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells. / 09.2020 / PubMed / Full text
• Effectiveness of adjuvant FOLFOX vs 5FU/LV in adults over age 65 with stage II and III colon cancer using a novel hybrid approach. / 12.2020 / PubMed / Full text
• Age, Frailty, and Comorbidity as Prognostic Factors for Short-Term Outcomes in Patients With Coronavirus Disease 2019 in Geriatric Care. / 11.2020 / PubMed / Full text
• Clinical and demographic parameters predict the progression from mild cognitive impairment to dementia in elderly patients. / 12.09.2020 / PubMed / Full text
• Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women. / 01.12.2020 / PubMed / Full text
• High intensity interval training combined with L-citrulline supplementation: Effects on physical performance in healthy older adults. / 15.10.2020 / PubMed / Full text
• Associations of blood pressure with risk of injurious falls in old age vary by functional status: A cohort study. / 15.10.2020 / PubMed / Full text
• Epigenetic age acceleration and clinical outcomes in gliomas. / 2020 / PubMed / Full text
• Do Stairs Inhibit Seniors Who Live on Upper Floors From Going Out? / 10.2020 / PubMed / Full text
• Age-specific acute changes in carotid-femoral pulse wave velocity with head-up tilt. / 07.07.2020 / PubMed / Full text
• Pre-frailty status increases the risk of rehospitalization in patients after elective cardiac surgery without complication. / 06.2020 / PubMed / Full text
• Comparative Performance of Creatinine-Based GFR Estimation Equations in Exceptional Longevity: The Rugao Longevity and Ageing Study. / 2020 / PubMed / Full text
• Sex-and race-specific associations of protein intake with change in muscle mass and physical function in older adults: the Health, Aging, and Body Composition (Health ABC) Study. / 01.07.2020 / PubMed / Full text
• Deterioration of bone microstructure by aging and menopause in Japanese healthy women: analysis by HR-pQCT. / 11.2020 / PubMed / Full text
• Association between Low Protein Intake and Mortality in Patients with Type 2 Diabetes. / 01.06.2020 / PubMed / Full text
• CAUSES, mortality rates and risk factors of death in community-dwelling Europeans aged 50 years and over: Results from the Survey of Health, Ageing and Retirement in Europe 2013-2015. / 07-08.2020 / PubMed / Full text
• Estimation of Wave Condition Number From Pressure Waveform Alone and Its Changes With Advancing Age in Healthy Women and Men. / 2020 / PubMed / Full text
• Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition. / 07.2020 / PubMed / Full text
• Effect of artificial dawn light on cardiovascular function, alertness, and balance in middle-aged and older adults. / 13.10.2020 / PubMed / Full text
• Heart Rate Performance Curve Is Dependent on Age, Sex, and Performance. / 2020 / PubMed / Full text
• Physical activity trajectories, mortality, hospitalization, and disability in the Toledo Study of Healthy Aging. / 08.2020 / PubMed / Full text
• U-Shaped Association of Plasma Testosterone, and no Association of Plasma Estradiol, with Incidence of Fractures in Men. / 01.05.2020 / PubMed / Full text
• Pregnancy-Related Bone Mineral and Microarchitecture Changes in Women Aged 30 to 45 Years. / 07.2020 / PubMed / Full text
• Analysis of the world record time for combined father and son marathon. / 01.02.2020 / PubMed / Full text
• Age-related reductions in heart rate variability do not worsen during exposure to humid compared to dry heat: A secondary analysis. / 2019 / PubMed / Full text
• Efficacy and Safety of Dapagliflozin in the Elderly: Analysis From the DECLARE-TIMI 58 Study. / 02.2020 / PubMed / Full text
• Validity of Prediction Equations of Maximal Heart Rate in Physically Active Female Adolescents and the Role of Maturation. / 13.11.2019 / PubMed / Full text
• Base excision repair but not DNA double-strand break repair is impaired in aged human adipose-derived stem cells. / 02.2020 / PubMed / Full text
• Urban-Rural Differences in Hip Fracture Mortality: A Nationwide NOREPOS Study. / 11.2019 / PubMed / Full text
• Malnutrition as a Strong Predictor of the Onset of Sarcopenia. / 27.11.2019 / PubMed / Full text
• Acclimation to a thermoneutral environment abolishes age-associated alterations in heart rate and heart rate variability in conscious, unrestrained mice. / 02.2020 / PubMed / Full text
• Long-term dementia risk prediction by the LIBRA score: A 30-year follow-up of the CAIDE study. / 02.2020 / PubMed / Full text
• Kidney function and its association to imminent, short- and long-term fracture risk-a longitudinal study in older women. / 01.2020 / PubMed / Full text
• Oxidatively Damaged DNA/RNA and 8-Isoprostane Levels Are Associated With the Development of Type 2 Diabetes at Older Age: Results From a Large Cohort Study. / 01.2020 / PubMed / Full text
• Associations of vigorous physical activity with all-cause, cardiovascular and cancer mortality among 64 913 adults. / 2019 / PubMed / Full text
• Reduced cerebrovascular and cardioventilatory responses to intermittent hypoxia in elderly. / 01.2020 / PubMed / Full text
• Vestibulo-sympathetic reflex in patients with bilateral vestibular loss. / 01.11.2019 / PubMed / Full text
• Heart rate and blood pressure in male Ts65Dn mice: a model to investigate cardiovascular responses in Down syndrome. / 09.2019 / PubMed / Full text
• Body weight at 10 years of age and change in body composition between 8 and 10 years of age were related to survival in a longitudinal study of 39 Labrador retriever dogs. / 09.09.2019 / PubMed / Full text
• Dietary diversity offsets the adverse mortality risk among older indigenous Taiwanese. / 2019 / PubMed / Full text
• Independent and joint effects of vascular and cardiometabolic risk factor pairs for risk of all-cause dementia: a prospective population-based study. / 10.2019 / PubMed / Full text
• Work Ability and Job Survival: Four-Year Follow-Up. / 28.08.2019 / PubMed / Full text
• Predictivity of bioimpedance phase angle for incident disability in older adults. / 02.2020 / PubMed / Full text

APOE

• Polygenic risk score of longevity predicts longer survival across an age-continuum. / 20.11.2020 / PubMed / Full text
• Association Between APOE Alleles and Change of Neuropsychological Tests in the Long Life Family Study. / 17.11.2020 / PubMed / Full text
• The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans. / 20.11.2020 / PubMed / Full text
• Homozygosity in the [i]APOE[/i] 3 Polymorphism Is Associated With Less Depression and Higher Serum Low-Density Lipoprotein in Chinese Elderly Schizophrenics. / 2020 / PubMed / Full text
• Effect of apolipoprotein E polymorphism on cognition and brain in the Cambridge Centre for Ageing and Neuroscience cohort. / 01-12.2020 / PubMed / Full text
• Cardiovascular risk factors and APOE-ε4 status affect memory functioning in aging via changes to temporal stem diffusion. / 18.10.2020 / PubMed / Full text
• APOE [i]ε[/i]4 and resting-state functional connectivity in racially/ethnically diverse older adults. / 2020 / PubMed / Full text
• Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study. / 13.11.2020 / PubMed / Full text
• When Culture Influences Genes: Positive Age Beliefs Amplify the Cognitive-Aging Benefit of APOE ε2. / 14.09.2020 / PubMed / Full text
• Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study. / 08.2020 / PubMed / Full text
• Estimating the potential for dementia prevention through modifiable risk factors elimination in the real-world setting: a population-based study. / 07.08.2020 / PubMed / Full text
• Machine learning-based estimation of cognitive performance using regional brain MRI markers: the Northern Manhattan Study. / 01.08.2020 / PubMed / Full text
• Effects of an APOE Promoter Polymorphism on Fronto-Parietal Functional Connectivity During Nondemented Aging. / 2020 / PubMed / Full text
• The relationship of parental longevity with the aging brain-results from UK Biobank. / 10.2020 / PubMed / Full text
• Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation. / 30.06.2020 / PubMed / Full text
• Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease. / 2020 / PubMed / Full text
• Effects of sex, age, and apolipoprotein E genotype on hippocampal parenchymal fraction in cognitively normal older adults. / 30.07.2020 / PubMed / Full text
• Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO). / 05.05.2020 / PubMed / Full text
• Apolipoprotein E and Health in Older Men: The Concord Health and Ageing in Men Project. / 25.09.2020 / PubMed / Full text
• CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease. / 07.2020 / PubMed / Full text
• Association of Cardiovascular Risk Factors with Cerebral Perfusion in Whites and African Americans. / 2020 / PubMed / Full text
• Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways. / 03.06.2020 / PubMed / Full text
• Less agreeable, better preserved? A PET amyloid and MRI study in a community-based cohort. / 05.2020 / PubMed / Full text
• Physical Activity as Moderator of the Association Between APOE and Cognitive Decline in Older Adults: Results from Three Longitudinal Cohort Studies. / 25.09.2020 / PubMed / Full text
• Longitudinal Maintenance of Cognitive Health in Centenarians in the 100-plus Study. / 05.02.2020 / PubMed / Full text
• Interaction of APOE, cerebral blood flow, and cortical thickness in the entorhinal cortex predicts memory decline. / 04.2020 / PubMed / Full text
• Determinants of mesial temporal lobe volume loss in older individuals with preserved cognition: a longitudinal PET amyloid study. / 03.2020 / PubMed / Full text
• Long-term exposure to ambient air pollution, APOE-ε4 status, and cognitive decline in a cohort of older adults in northern Manhattan. / 03.2020 / PubMed / Full text
• Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice. / 2020 / PubMed / Full text
• APOE region molecular signatures of Alzheimer's disease across races/ethnicities. / 03.2020 / PubMed / Full text
• Varying Effects of APOE Alleles on Extreme Longevity in European Ethnicities. / 13.11.2019 / PubMed / Full text
• Prospective Evaluation of Cognitive Health and Related Factors in Elderly at Risk for Developing Alzheimer's Dementia: A Longitudinal Cohort Study. / 2019 / PubMed / Full text
• Association of Cardiovascular and Alzheimer's Disease Risk Factors with Intracranial Arterial Blood Flow in Whites and African Americans. / 2019 / PubMed / Full text
• Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease? / 17.04.2020 / PubMed / Full text
• Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study. / 02.2020 / PubMed / Full text
• Prospective Memory: Age related change is influenced by APOE genotype. / 09.2020 / PubMed / Full text
• Education Moderates the Relation Between APOE ɛ4 and Memory in Nondemented Non-Hispanic Black Older Adults. / 2019 / PubMed / Full text
• Apolipoprotein E ε4 allele effects on longitudinal cognitive trajectories are sex and age dependent. / 12.2019 / PubMed / Full text
• Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects. / 2019 / PubMed / Full text
• APOE modifies the interaction of entorhinal cerebral blood flow and cortical thickness on memory function in cognitively normal older adults. / 15.11.2019 / PubMed / Full text
• When time's arrow doesn't bend: APOE-ε4 influences episodic memory before old age. / 10.2019 / PubMed / Full text
• Cognitive-Motor Integration Performance Is Affected by Sex, APOE Status, and Family History of Dementia. / 2019 / PubMed / Full text
• Associations among amyloid status, age, and longitudinal regional brain atrophy in cognitively unimpaired older adults. / 10.2019 / PubMed / Full text
• Cognitive function and neuropathological outcomes: a forward-looking approach. / 12.2019 / PubMed / Full text
• APOE gene-dependent BOLD responses to a breath-hold across the adult lifespan. / 2019 / PubMed / Full text

MSC

• Rejuvenation of Senescent Endothelial Progenitor Cells by Extracellular Vesicles Derived From Mesenchymal Stromal Cells. / 11.2020 / PubMed / Full text
• Extracellular vesicles derived from bone marrow mesenchymal stem cells enhance myelin maintenance after cortical injury in aged rhesus monkeys. / 29.11.2020 / PubMed / Full text
• TPP1 Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the MRE11/AKT Pathway. / 2020 / PubMed / Full text
• Aging-Affected MSC Functions and Severity of Periodontal Tissue Destruction in a Ligature-Induced Mouse Periodontitis Model. / 30.10.2020 / PubMed / Full text
• Human placenta-derived mesenchymal stem cells stimulate ovarian function via miR-145 and bone morphogenetic protein signaling in aged rats. / 05.11.2020 / PubMed / Full text
• Mesenchymal Stromal Cells as Critical Contributors to Tissue Regeneration. / 2020 / PubMed / Full text
• The biology of human hair greying. / 23.09.2020 / PubMed / Full text
• [i]Tsc1[/i] Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells. / 10.09.2020 / PubMed / Full text
• The role of mitochondrial dysfunction in mesenchymal stem cell senescence. / 12.2020 / PubMed / Full text
• Metabolic syndrome increases senescence-associated micro-RNAs in extracellular vesicles derived from swine and human mesenchymal stem/stromal cells. / 12.08.2020 / PubMed / Full text
• Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses. / 22.07.2020 / PubMed / Full text
• Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organization in stress-induced senescence of MSCs. / 13.07.2020 / PubMed / Full text
• Increased cellular senescence in the murine and human stenotic kidney: Effect of mesenchymal stem cells. / 02.2021 / PubMed / Full text
• Intrinsic Type 1 Interferon (IFN1) Profile of Uncultured Human Bone Marrow CD45 CD271 Multipotential Stromal Cells (BM-MSCs): The Impact of Donor Age, Culture Expansion and IFNα and IFNβ Stimulation. / 15.07.2020 / PubMed / Full text
• Facial rejuvenation using stem cell conditioned media combined with skin needling: A split-face comparative study. / 09.2020 / PubMed / Full text
• Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges. / 2020 / PubMed / Full text
• The changing epigenetic landscape of Mesenchymal Stem/Stromal Cells during aging. / 08.2020 / PubMed / Full text
• Dual Role of Autophagy in Regulation of Mesenchymal Stem Cell Senescence. / 2020 / PubMed / Full text
• Molecular Aspects of Adipose-Derived Stromal Cell Senescence in a Long-Term Culture: A Potential Role of Inflammatory Pathways. / 01-12.2020 / PubMed / Full text
• Human Obesity Induces Dysfunction and Early Senescence in Adipose Tissue-Derived Mesenchymal Stromal/Stem Cells. / 2020 / PubMed / Full text
• miR-155-5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction. / 04.2020 / PubMed / Full text
• Mesenchymal Stem Cell Derived Extracellular Vesicles in Aging. / 2020 / PubMed / Full text
• Molecular Mechanisms Contributing to Mesenchymal Stromal Cell Aging. / 21.02.2020 / PubMed / Full text
• Inhibition of DNA Methyltransferase by RG108 Promotes Pluripotency-Related Character of Porcine Bone Marrow Mesenchymal Stem Cells. / 04.2020 / PubMed / Full text
• Extracellular Vesicles of Stem Cells to Prevent BRONJ. / 05.2020 / PubMed / Full text
• Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells. / 2019 / PubMed / Full text
• The Importance of Stem Cell Senescence in Regenerative Medicine. / 2020 / PubMed / Full text
• Control of mesenchymal stem cell biology by histone modifications. / 2020 / PubMed / Full text
• Impact of mesenchymal stem cell senescence on inflammaging. / 02.2020 / PubMed / Full text
• Late Rescue Therapy with Cord-Derived Mesenchymal Stromal Cells for Established Lung Injury in Experimental Bronchopulmonary Dysplasia. / 15.03.2020 / PubMed / Full text
• Low-Level Radiofrequency Exposure Does Not Induce Changes in MSC Biology: An in vitro Study for the Prevention of NIR-Related Damage. / 2019 / PubMed / Full text
• Macrophage migration inhibitory factor rejuvenates aged human mesenchymal stem cells and improves myocardial repair. / 27.12.2019 / PubMed / Full text
• Influence of olive oil and its components on mesenchymal stem cell biology. / 26.12.2019 / PubMed / Full text
• Epigenetic Regulation of Mesenchymal Stem Cell Homeostasis. / 02.2020 / PubMed / Full text
• Mesenchymal Stem Cells: Allogeneic MSC May Be Immunosuppressive but Autologous MSC Are Dysfunctional in Lupus Patients. / 2019 / PubMed / Full text
• Effects of high glucose conditions on the expansion and differentiation capabilities of mesenchymal stromal cells derived from rat endosteal niche. / 21.11.2019 / PubMed / Full text
• Autophagy inhibits the mesenchymal stem cell aging induced by D-galactose through ROS/JNK/p38 signalling. / 03.2020 / PubMed / Full text
• Enhancing survival, engraftment, and osteogenic potential of mesenchymal stem cells. / 26.10.2019 / PubMed / Full text
• Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development. / 22.10.2019 / PubMed / Full text
• Embryonic stem cell-derived extracellular vesicles enhance the therapeutic effect of mesenchymal stem cells. / 2019 / PubMed / Full text
• Survival of aging CD264 and CD264 populations of human bone marrow mesenchymal stem cells is independent of colony-forming efficiency. / 01.2020 / PubMed / Full text
• Differential effects of extracellular vesicles from aging and young mesenchymal stem cells in acute lung injury. / 29.09.2019 / PubMed / Full text
• Connexin43 is Dispensable for Early Stage Human Mesenchymal Stem Cell Adipogenic Differentiation But is Protective against Cell Senescence. / 11.09.2019 / PubMed / Full text
• Maintained Properties of Aged Dental Pulp Stem Cells for Superior Periodontal Tissue Regeneration. / 08.2019 / PubMed / Full text

SIRT1

• Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats. / 03.12.2020 / PubMed / Full text
• Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective. / 05.12.2020 / PubMed / Full text
• Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells. / 10.2020 / PubMed / Full text
• SIRT1 Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence. / 04.11.2020 / PubMed / Full text
• Histone Deacetylase SIRT1, Smooth Muscle Cell Function, and Vascular Diseases. / 2020 / PubMed / Full text
• 6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing SIRT1 and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation. / 27.10.2020 / PubMed / Full text
• Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through SIRT1 activation and AKT/mTOR pathway inhibition. / 30.09.2020 / PubMed / Full text
• SIRT1 Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence. / 2020 / PubMed / Full text
• The Role of Sirtuins in Kidney Diseases. / 12.09.2020 / PubMed / Full text
• The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. / 11.2020 / PubMed / Full text
• Virus-Induced Asthma Exacerbations: SIRT1 Targeted Approach. / 13.08.2020 / PubMed / Full text
• Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts. / 12.2020 / PubMed / Full text
• Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/SIRT1-FOXA3-Beclin1 pathway. / 01.10.2020 / PubMed / Full text
• Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence. / 08.2020 / PubMed / Full text
• Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of SIRT1 in Human Dermal Fibroblasts. / 01.07.2020 / PubMed / Full text
• SRT1720-induced activation of SIRT1 alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485. / 07.2020 / PubMed / Full text
• miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss. / 2020 / PubMed / Full text
• Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes. / 01-12.2020 / PubMed / Full text
• Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats. / 10.2020 / PubMed / Full text
• The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis. / 2020 / PubMed / Full text
• Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells. / 2020 / PubMed / Full text
• Spatiotemporal gating of SIRT1 functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia. / 24.03.2020 / PubMed / Full text
• Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of SIRT1. / 2020 / PubMed / Full text
• SIRT1 and aging related signaling pathways. / 04.2020 / PubMed / Full text
• Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of SIRT1 signaling. / 01.05.2020 / PubMed / Full text
• Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. / 04.2020 / PubMed / Full text
• Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells. / 01.05.2020 / PubMed / Full text
• Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal SIRT1 Levels Improving Cognition in Aged Rats. / 26.01.2020 / PubMed / Full text
• Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating SIRT1. / 01.2020 / PubMed / Full text
• Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence. / 06-07.2020 / PubMed / Full text
• Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1. / 23.12.2019 / PubMed / Full text
• The protective role of omentin-1 in IL-1β-induced chondrocyte senescence. / 12.2020 / PubMed / Full text
• The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD Level Is Lower than the Sirtuin-Saturating Concentrations. / 24.12.2019 / PubMed / Full text
• Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells. / 06.2020 / PubMed / Full text
• Central nervous system SIRT1 expression is required for cued and contextual fear conditioning memory responses in aging mice. / 23.09.2019 / PubMed / Full text
• Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education. / 10.2019 / PubMed
• CO ameliorates endothelial senescence induced by 5-fluorouracil through SIRT1 activation. / 30.11.2019 / PubMed / Full text
• Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating SIRT1 expression. / 20.10.2019 / PubMed / Full text
• The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging. / 2019 / PubMed / Full text
• Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. / 03.2020 / PubMed / Full text
• Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure. / 13.02.2020 / PubMed / Full text
• Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of SIRT1. / 2019 / PubMed / Full text
• Activation of the miR-34a-Mediated SIRT1/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice. / 10.2019 / PubMed / Full text

RPE

• Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time. / 08.12.2020 / PubMed / Full text
• Relationship between Oxygen Uptake, Heart Rate, and Perceived Effort in an Aquatic Incremental Test in Older Women. / 11.11.2020 / PubMed / Full text
• Photoreceptor Degeneration in Homozygous Male Per2 Mice During Aging. / 02.11.2020 / PubMed / Full text
• An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into RPE Stress Associated with Retinopathy. / 11.09.2020 / PubMed / Full text
• Short-Term Effect of Self-Selected Training Intensity on Ambulatory Blood Pressure in Hypertensive Older Women: A Randomized Controlled Trial. / 2020 / PubMed / Full text
• Correlation between brain volume and retinal photoreceptor outer segment volume in normal aging and neurodegenerative diseases. / 2020 / PubMed / Full text
• Oxidative stress in the retina and retinal pigment epithelium (RPE): Role of aging, and DJ-1. / 17.07.2020 / PubMed / Full text
• Direct-Coupled Electroretinogram (DC-ERG) for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium. / 14.07.2020 / PubMed / Full text
• High-density lipoproteins are a potential therapeutic target for age-related macular degeneration. / 25.09.2020 / PubMed / Full text
• MTOR-initiated metabolic switch and degeneration in the retinal pigment epithelium. / 09.2020 / PubMed / Full text
• [i]Lactobacillus paracasei[/i] KW3110 Suppresses Inflammatory Stress-Induced Premature Cellular Senescence of Human Retinal Pigment Epithelium Cells and Reduces Ocular Disorders in Healthy Humans. / 18.07.2020 / PubMed / Full text
• Retinal pigment epithelium transcriptome analysis in chronic smoking reveals a suppressed innate immune response and activation of differentiation pathways. / 20.08.2020 / PubMed / Full text
• Differences in Intraretinal Pigment Migration Across Inherited Retinal Dystrophies. / 09.2020 / PubMed / Full text
• Exosomal MiRNA Transfer between Retinal Microglia and RPE. / 17.05.2020 / PubMed / Full text
• Functionally validated imaging endpoints in the Alabama study on early age-related macular degeneration 2 (ALSTAR2): design and methods. / 19.05.2020 / PubMed / Full text
• Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration. / 13.04.2020 / PubMed / Full text
• CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization. / 01.04.2020 / PubMed / Full text
• Extracellular microparticles exacerbate oxidative damage to retinal pigment epithelial cells. / 01.05.2020 / PubMed / Full text
• Water-based continuous and interval training in older women: Cardiorespiratory and neuromuscular outcomes (WATER study). / 05.03.2020 / PubMed / Full text
• Retrieval Practice Improves Recollection-Based Memory Over a Seven-Day Period in Younger and Older Adults. / 2019 / PubMed / Full text
• A Comparison of Heart Rate Training Load and Perceptual Effort Between Masters and Young Cyclists / 01.05.2020 / PubMed / Full text
• Retinal Pigment Epithelial Cells: The Unveiled Component in the Etiology of Prpf Splicing Factor-Associated Retinitis Pigmentosa. / 2019 / PubMed / Full text
• AMPK May Play an Important Role in the Retinal Metabolic Ecosystem. / 2019 / PubMed / Full text
• Stem cell-derived retinal pigment epithelium from patients with age-related macular degeneration exhibit reduced metabolism and matrix interactions. / 03.2020 / PubMed / Full text
• Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptors. / 26.11.2019 / PubMed / Full text
• Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina. / 19.11.2019 / PubMed / Full text
• Age, lipofuscin and melanin oxidation affect fundus near-infrared autofluorescence. / 10.2019 / PubMed / Full text
• Relevance of working memory for reinforcement learning in older adults varies with timescale of learning. / 09.2020 / PubMed / Full text
• Expression and Function of Mas-Related G Protein-Coupled Receptor D and Its Ligand Alamandine in Retina. / 01.2020 / PubMed / Full text

CRP

• Omega-3 supplementation improves isometric strength but not muscle anabolic and catabolic signaling in response to resistance exercise in healthy older adults. / 07.12.2020 / PubMed / Full text
• Circulating angiopoietin-like protein 2 levels and arterial stiffness in patients receiving maintenance hemodialysis: A cross-sectional study. / 02.11.2020 / PubMed / Full text
• Cardiovascular rehabilitation in patients aged 70-year-old or older: benefits on functional capacity, physical activity and metabolic profile in younger [i]vs[/i]. older patients. / 28.09.2020 / PubMed / Full text
• rRT-PCR Results of a Covid-19 Diagnosed Geriatric Patient. / 17.10.2020 / PubMed / Full text
• The Association of Aging Biomarkers, Interstitial Lung Abnormalities, and Mortality. / 20.10.2020 / PubMed / Full text
• A Novel Fortified Dairy Product and Sarcopenia Measures in Sarcopenic Older Adults: A Double-Blind Randomized Controlled Trial. / 13.10.2020 / PubMed / Full text
• Age-Related Colonic Mucosal Microbiome Community Shifts in Monkeys. / 06.10.2020 / PubMed / Full text
• The relationship between frailty and serum alpha klotho levels in geriatric patients. / 08.08.2020 / PubMed / Full text
• ZMPSTE24 Is Associated with Elevated Inflammation and Progerin mRNA. / 28.08.2020 / PubMed / Full text
• Cultural and life style practices associated with low inflammatory physiology in Japanese adults. / 11.2020 / PubMed / Full text
• Moderate- to high intensity aerobic and resistance exercise reduces peripheral blood regulatory cell populations in older adults with rheumatoid arthritis. / 2020 / PubMed / Full text
• PTSD and the klotho longevity gene: Evaluation of longitudinal effects on inflammation via DNA methylation. / 07.2020 / PubMed / Full text
• Bereavement is associated with reduced systemic inflammation: C-reactive protein before and after widowhood. / 08.2020 / PubMed / Full text
• The Impact of Age on the Prevalence of Sarcopenic Obesity in Bariatric Surgery Candidates. / 06.2020 / PubMed / Full text
• Intake of dietary advanced glycation end products influences inflammatory markers, immune phenotypes, and antiradical capacity of healthy elderly in a little-studied population. / 02.2020 / PubMed / Full text
• Intentional Switching Between Bimanual Coordination Patterns in Older Adults: Is It Mediated by Inhibition Processes? / 2020 / PubMed / Full text
• Shorter Telomere Length in Peripheral Blood Leukocytes Is Associated with Post-Traumatic Chronic Osteomyelitis. / 11.2020 / PubMed / Full text
• Risk Factors of Progression to Frailty: Findings from the Singapore Longitudinal Ageing Study. / 2020 / PubMed / Full text
• Physical Function and Strength in Relation to Inflammation in Older Adults with Obesity and Increased Cardiometabolic Risk. / 2019 / PubMed / Full text
• Key diagnostic characteristics of fever of unknown origin in Japanese patients: a prospective multicentre study. / 19.11.2019 / PubMed / Full text
• Decrease in Serum Vitamin D Level of Older Patients with Fatigue. / 20.10.2019 / PubMed / Full text
• The Association between Frailty Indicators and Blood-Based Biomarkers in Early-Old Community Dwellers of Thailand. / 17.09.2019 / PubMed / Full text
• Associations of C-reactive protein and homocysteine concentrations with the impairment of intrinsic capacity domains over a 5-year follow-up among community-dwelling older adults at risk of cognitive decline (MAPT Study). / 11.2019 / PubMed / Full text
• Longitudinal analysis of loneliness and inflammation at older ages: English longitudinal study of ageing. / 12.2019 / PubMed / Full text
• The cortisol burden in elderly subjects with metabolic syndrome and its association with low-grade inflammation. / 07.2020 / PubMed / Full text
• Recurrent circadian fasting (RCF) improves blood pressure, biomarkers of cardiometabolic risk and regulates inflammation in men. / 19.08.2019 / PubMed / Full text
• Characteristics of patients with rheumatoid arthritis undergoing primary total joint replacement: A 14-year trend analysis (2004-2017). / 07.2020 / PubMed / Full text

CA1

• The relation between tau pathology and granulovacuolar degeneration of neurons. / 01.2021 / PubMed / Full text
• Memory and dendritic spines loss, and dynamic dendritic spines changes are age-dependent in the rat. / 12.2020 / PubMed / Full text
• Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis. / 04.09.2020 / PubMed / Full text
• COX5A Plays a Vital Role in Memory Impairment Associated With Brain Aging [i]via[/i] the BDNF/ERK1/2 Signaling Pathway. / 2020 / PubMed / Full text
• Changes of fat-mass and obesity-associated protein expression in the hippocampus in animal models of high-fat diet-induced obesity and D-galactose-induced aging. / 2020 / PubMed / Full text
• Phenylbutyrate ameliorates prefrontal cortex, hippocampus, and nucleus accumbens neural atrophy as well as synaptophysin and GFAP stress in aging mice. / 11.2020 / PubMed / Full text
• Heterogeneity in brain distribution of activated microglia and astrocytes in a rat ischemic model of Alzheimer's disease after 2 years of survival. / 05.06.2020 / PubMed / Full text
• Hippocampal Subregion Transcriptomic Profiles Reflect Strategy Selection during Cognitive Aging. / 17.06.2020 / PubMed / Full text
• Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan: A 7 T imaging study. / 05.05.2020 / PubMed / Full text
• Laminarin Pretreatment Provides Neuroprotection against Forebrain Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Neuroinflammation in Aged Gerbils. / 15.04.2020 / PubMed / Full text
• Age-dependent Alteration in Mitochondrial Dynamics and Autophagy in Hippocampal Neuron of Cannabinoid CB1 Receptor-deficient Mice. / 07.2020 / PubMed / Full text
• Functional Connectivity of Hippocampal CA3 Predicts Neurocognitive Aging via CA1-Frontal Circuit. / 30.06.2020 / PubMed / Full text
• Integration of qRT-PCR and Immunohistochemical Techniques for mRNA Expression and Localization of m1AChR in the Brain of Aging Rat. / 2020 / PubMed / Full text
• Role of Eclipta prostrata extract in improving spatial learning and memory deficits in D-galactose-induced aging in rats. / 10.2019 / PubMed
• Differential annualized rates of hippocampal subfields atrophy in aging and future Alzheimer's clinical syndrome. / 06.2020 / PubMed / Full text
• Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1 stem cells from young donors. / 07.02.2020 / PubMed / Full text
• Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life. / 09.01.2020 / PubMed / Full text
• Memory Performance Correlates of Hippocampal Subfield Volume in Mild Cognitive Impairment Subtype. / 2019 / PubMed / Full text
• Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses. / 23.12.2019 / PubMed / Full text
• Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice. / 16.12.2019 / PubMed / Full text
• Long-term Memory Upscales Volume of Postsynaptic Densities in the Process that Requires Autophosphorylation of αCaMKII. / 14.04.2020 / PubMed / Full text
• PACAP27 mitigates an age-dependent hippocampal vulnerability to PGJ2-induced spatial learning deficits and neuroinflammation in mice. / 01.2020 / PubMed / Full text
• Inhibition of oxidative stress by testosterone improves synaptic plasticity in senescence accelerated mice. / 2019 / PubMed / Full text
• Restored presynaptic synaptophysin and cholinergic inputs contribute to the protective effects of physical running on spatial memory in aged mice. / 12.2019 / PubMed / Full text
• Senescent neurophysiology: Ca signaling from the membrane to the nucleus. / 10.2019 / PubMed / Full text

GC

• Body Size and Cuticular Hydrocarbons as Larval Age Indicators in the Forensic Blow Fly, Chrysomya albiceps (Diptera: Calliphoridae). / 04.12.2020 / PubMed / Full text
• Composition of peony petal fatty acids and flavonoids and their effect on Caenorhabditis elegans lifespan. / 10.2020 / PubMed / Full text
• Photo aging and fragmentation of polypropylene food packaging materials in artificial seawater. / 01.01.2021 / PubMed / Full text
• Secretory galectin-3 induced by glucocorticoid stress triggers stemness exhaustion of hepatic progenitor cells. / 04.12.2020 / PubMed / Full text
• Optimization of Ethanol Detection by Automatic Headspace Method for Cellulose Insulation Aging of Oil-immersed Transformers. / 15.07.2020 / PubMed / Full text
• Sensory, olfactometric and chemical characterization of the aroma potential of Garnacha and Tempranillo winemaking grapes. / 30.11.2020 / PubMed / Full text
• Accelerated Cognitive Ageing in epilepsy: exploring the effective connectivity between resting-state networks and its relation to cognitive decline. / 06.2020 / PubMed / Full text
• Characterization of Jinhua ham aroma profiles in specific to aging time by gas chromatography-ion mobility spectrometry (GC-IMS). / 10.2020 / PubMed / Full text
• Quantitative Profiling of Lipid Species in Caenorhabditis elegans with Gas Chromatography-Mass Spectrometry. / 2020 / PubMed / Full text
• Physicochemical characterization of a polysaccharide from Agrocybe aegirita and its anti-ageing activity. / 15.05.2020 / PubMed / Full text
• Structural characteristics, antioxidant properties and antiaging activities of galactan produced by Mentha haplocalyx Briq. / 15.04.2020 / PubMed / Full text
• Contribution of Volatile Odorous Terpenoid Compounds to Aged Cognac Spirits Aroma in a Context of Multicomponent Odor Mixtures. / 25.11.2020 / PubMed / Full text
• Plasma Formate Is Greater in Fetal and Neonatal Rats Compared with Their Mothers. / 01.05.2020 / PubMed / Full text
• Development of a new strategy for studying the aroma potential of winemaking grapes through the accelerated hydrolysis of phenolic and aromatic fractions (PAFs). / 01.2020 / PubMed / Full text
• Compromised steady-state germinal center activity with age in nonhuman primates. / 02.2020 / PubMed / Full text
• Endogenous Glucocorticoid Signaling in the Regulation of Bone and Marrow Adiposity: Lessons from Metabolism and Cross Talk in Other Tissues. / 12.2019 / PubMed / Full text
• 4,5-Diphenyl-2-methyl picolinate induces cellular senescence by accumulating DNA damage and activating associated signaling pathways in gastric cancer. / 01.12.2019 / PubMed / Full text
• Relationship Between the Dose Administered, Target Tissue Dose, and Toxicity Level After Acute Oral Exposure to Bifenthrin and Tefluthrin in Young Adult Rats. / 01.12.2019 / PubMed / Full text
• Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly. / 12.09.2019 / PubMed / Full text
• Identification and analysis of new α- and β-hydroxy ketones related to the formation of 3-methyl-2,4-nonanedione in musts and red wines. / 01.02.2020 / PubMed / Full text
• Neonatal T Follicular Helper Cells Are Lodged in a Pre-T Follicular Helper Stage Favoring Innate Over Adaptive Germinal Center Responses. / 2019 / PubMed / Full text
• Identification of Dialkylpyrazines Off-Flavors in Oak Wood. / 11.09.2019 / PubMed / Full text
• Metabolomics Coupled with Transcriptomics Approach Deciphering Age Relevance in Sepsis. / 08.2019 / PubMed / Full text

NLRP3

• Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience. / 12.2020 / PubMed / Full text
• TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity. / 27.10.2020 / PubMed / Full text
• Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and NLRP3 inflammasome. / 01.01.2021 / PubMed / Full text
• A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma. / 13.10.2020 / PubMed / Full text
• Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress. / 2020 / PubMed / Full text
• Mechanisms of NLRP3 priming in inflammaging and age related diseases. / 10.2020 / PubMed / Full text
• Lamivudine Inhibits [i]Alu[/i] RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities. / 07.2020 / PubMed / Full text
• The NLRP3 Inflammasome: Metabolic Regulation and Contribution to Inflammaging. / 30.07.2020 / PubMed / Full text
• Aging aggravated liver ischemia and reperfusion injury by promoting STING-mediated NLRP3 activation in macrophages. / 08.2020 / PubMed / Full text
• Targeting NLRP3 Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss. / 10.2020 / PubMed / Full text
• Korean Red Ginseng Suppresses the Expression of Oxidative Stress Response and NLRP3 Inflammasome Genes in Aged C57BL/6 Mouse Ovaries. / 22.04.2020 / PubMed / Full text
• Cepharanthine promotes the effect of dexmedetomidine on the deposition of β-amyloid in the old age of the senile dementia rat model by regulating inflammasome expression. / 2019 / PubMed / Full text
• Ginsenoside Rg1 ameliorates glomerular fibrosis during kidney aging by inhibiting NOX4 and NLRP3 inflammasome activation in SAMP8 mice. / 27.02.2020 / PubMed / Full text
• Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice. / 04.2020 / PubMed / Full text
• Autophagy and NLRP3 inflammasome crosstalk in neuroinflammation in aged bovine brains. / 06.2020 / PubMed / Full text
• NLRP3 Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity. / 13.07.2020 / PubMed / Full text
• NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice. / 01.2020 / PubMed / Full text
• Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging. / 08.09.2019 / PubMed / Full text
• Effect of Aging on Taurine Transporter (TauT) Expression in the Mouse Brain Cortex. / 2019 / PubMed / Full text

SCD

• Cognitive training and brain stimulation in prodromal Alzheimer's disease (AD-Stim)-study protocol for a double-blind randomized controlled phase IIb (monocenter) trial. / 07.11.2020 / PubMed / Full text
• Blood Pressure in Different Dementia Disorders, Mild Cognitive Impairment, and Subjective Cognitive Decline. / 2020 / PubMed / Full text
• Known-Groups and Convergent Validity of the Telephone Rey Auditory Verbal Learning Test total Learning Scores for Distinguishing Between Older Adults With Amnestic Cognitive Impairment and Subjective Cognitive Decline. / 17.10.2020 / PubMed / Full text
• Subjective cognitive decline as a predictor of future cognitive decline: a systematic review. / 07-09.2020 / PubMed / Full text
• Geriatric assessment for older adults with sickle cell disease: protocol for a prospective cohort pilot study. / 2020 / PubMed / Full text
• Prevalence and psychosocial correlates of subjectively perceived decline in five cognitive domains: Results from a population-based cohort study in Germany. / 08.06.2020 / PubMed / Full text
• SC411 treatment can enhance survival in a mouse model of sickle cell disease. / 07.2020 / PubMed / Full text
• DNA fragmentation of human spermatozoa: Simple assessment of single- and double-strand DNA breaks and their respective dynamic behavioral response. / 09.2020 / PubMed / Full text
• Psychometric Cognitive Decline Precedes the Advent of Subjective Cognitive Decline in the Evolution of Alzheimer's Disease. / 2020 / PubMed / Full text
• Serum alkaline phosphatase is elevated and inversely correlated with cognitive functions in subjective cognitive decline: results from the ReGAl 2.0 project. / 03.05.2020 / PubMed / Full text
• Changes in Activity Participation Among Older Adults With Subjective Cognitive Decline or Objective Cognitive Deficits. / 2019 / PubMed / Full text
• Age, gender and drug therapy influences on Tpeak-tend interval and on electrical risk score. / 03-04.2020 / PubMed / Full text
• Comorbid Chronic Conditions Among Older Adults with Subjective Cognitive Decline, United States, 2015-2017. / 2020 / PubMed / Full text
• Resting State BOLD Variability Is Linked to White Matter Vascular Burden in Healthy Aging but Not in Older Adults With Subjective Cognitive Decline. / 2019 / PubMed / Full text
• Estimated Life Expectancy and Income of Patients With Sickle Cell Disease Compared With Those Without Sickle Cell Disease. / 01.11.2019 / PubMed / Full text
• Does Empirically Derived Classification of Individuals with Subjective Cognitive Complaints Predict Dementia? / 07.11.2019 / PubMed / Full text
• Spatiotemporal Oscillatory Patterns During Working Memory Maintenance in Mild Cognitive Impairment and Subjective Cognitive Decline. / 01.2020 / PubMed / Full text
• Microstructural Correlates and Laterality Effect of Prospective Memory in Non-Demented Adults with Memory Complaints. / 2019 / PubMed / Full text

BDNF

• Influence of [i]BDNF[/i] Genetic Polymorphisms in the Pathophysiology of Aging-related Diseases. / 12.2020 / PubMed / Full text
• Moderators of the Impact of (Poly)Phenols Interventions on Psychomotor Functions and BDNF: Insights from Subgroup Analysis and Meta-Regression. / 19.09.2020 / PubMed / Full text
• Astroglia-Derived BDNF and MSK-1 Mediate Experience- and Diet-Dependent Synaptic Plasticity. / 18.07.2020 / PubMed / Full text
• BDNF reverses aging-related microglial activation. / 14.07.2020 / PubMed / Full text
• High Supervised Resistance Training in Elderly Women: The Role of Supervision Ratio. / 2020 / PubMed / Full text
• Metformin regulates astrocyte reactivity in Parkinson's disease and normal aging. / 15.09.2020 / PubMed / Full text
• Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction. / 05.2020 / PubMed / Full text
• The Role of BDNF on Aging-Modulation Markers. / 09.05.2020 / PubMed / Full text
• Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice. / 08.04.2020 / PubMed / Full text
• Microglia senescence occurs in both substantia nigra and ventral tegmental area. / 11.2020 / PubMed / Full text
• Towards an understanding of the physical activity-BDNF-cognition triumvirate: A review of associations and dosage. / 07.2020 / PubMed / Full text
• Impact of BDNF and sex on maintaining intact memory function in early midlife. / 04.2020 / PubMed / Full text
• Testosterone replacement causes dose-dependent improvements in spatial memory among aged male rats. / 03.2020 / PubMed / Full text
• The effects of aerobic exercise intensity on memory in older adults. / 06.2020 / PubMed / Full text
• Protective effects of vitamin D on neurophysiologic alterations in brain aging: role of brain-derived neurotrophic factor (BDNF). / 16.09.2019 / PubMed / Full text
• Differential Effects of Physical Exercise, Cognitive Training, and Mindfulness Practice on Serum BDNF Levels in Healthy Older Adults: A Randomized Controlled Intervention Study. / 2019 / PubMed / Full text
• Dietary Supplementation with Fish Oil or Conjugated Linoleic Acid Relieves Depression Markers in Mice by Modulation of the Nrf2 Pathway. / 11.2019 / PubMed / Full text

TERT

• Telomeres and telomerase in risk assessment of cardiovascular diseases. / 15.12.2020 / PubMed / Full text
• A 4-Base-Pair Core-Enclosing Helix in Telomerase RNA Is Essential for Activity and for Binding to the Telomerase Reverse Transcriptase Catalytic Protein Subunit. / 20.11.2020 / PubMed / Full text
• Angiotensin inhibition and cellular senescence in the developing rat kidney. / 12.2020 / PubMed / Full text
• Decreased expression of TERT and telomeric proteins as human ovaries age may cause telomere shortening. / 27.08.2020 / PubMed / Full text
• The secrets of telomerase: Retrospective analysis and future prospects. / 15.09.2020 / PubMed / Full text
• Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides. / 06.2020 / PubMed / Full text
• Unravelling Cellular Mechanisms of Stem Cell Senescence: An Aid from Natural Bioactive Molecules. / 20.03.2020 / PubMed / Full text
• Expression of telomerase reverse transcriptase positively correlates with duration of lithium treatment in bipolar disorder. / 04.2020 / PubMed / Full text
• FAM96B inhibits the senescence of dental pulp stem cells. / 05.2020 / PubMed / Full text
• Aging and biomarkers: Transcriptional levels evaluation of Osteopontin/miRNA-181a axis in hepatic tissue of rats in different age ranges. / 05.2020 / PubMed / Full text
• Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells. / 04.2020 / PubMed / Full text
• Characterization of human telomerase reverse transcriptase immortalized anterior cruciate ligament cell lines. / 12.2019 / PubMed / Full text
• Mitochondria, Telomeres and Telomerase Subunits. / 2019 / PubMed / Full text
• Towards Therapeutic Alternatives for Mercury Neurotoxicity in the Amazon: Unraveling the Pre-Clinical Effects of the Superfruit Açaí ([i]Euterpe oleracea[/i], Mart.) as Juice for Human Consumption. / 26.10.2019 / PubMed / Full text
• Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing. / 08.10.2019 / PubMed / Full text
• Telomerase Biology Associations Offer Keys to Cancer and Aging Therapeutics. / 2020 / PubMed / Full text
• Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts. / 17.09.2019 / PubMed / Full text

PGC

• The Aging Stress Response and Its Implication for AMD Pathogenesis. / 22.11.2020 / PubMed / Full text
• Constitutive PGC-1α Overexpression in Skeletal Muscle Does Not Contribute to Exercise-Induced Neurogenesis. / 16.11.2020 / PubMed / Full text
• Dysregulated Autophagy Mediates Sarcopenic Obesity and Its Complications via AMPK and PGC1α Signaling Pathways: Potential Involvement of Gut Dysbiosis as a Pathological Link. / 19.09.2020 / PubMed / Full text
• Resemblance and differences in dietary restriction nephroprotective mechanisms in young and old rats. / 24.09.2020 / PubMed / Full text
• Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. / 08.2020 / PubMed / Full text
• PGC-1α-mediated regulation of mitochondrial function and physiological implications. / 09.2020 / PubMed / Full text
• Targeting Mitochondrial Network Architecture in Down Syndrome and Aging. / 29.04.2020 / PubMed / Full text
• Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner. / 06.2020 / PubMed / Full text
• A novel dipeptide from potato protein hydrolysate augments the effects of exercise training against high-fat diet-induced damages in senescence-accelerated mouse-prone 8 by boosting pAMPK / SIRT1/ PGC-1α/ pFOXO3 pathway. / 26.04.2020 / PubMed / Full text
• Mitochondrial nucleoid remodeling and biogenesis are regulated by the p53-p21 -PKCζ pathway in p16 -silenced cells. / 24.04.2020 / PubMed / Full text
• [Metabolic Alteration in Aging Process: Metabolic Remodeling in White Adipose Tissue by Caloric Restriction]. / 2020 / PubMed / Full text
• Kynurenine aminotransferase isoforms display fiber-type specific expression in young and old human skeletal muscle. / 15.02.2020 / PubMed / Full text
• Ubiquinol-10 delays postovulatory oocyte aging by improving mitochondrial renewal in pigs. / 20.01.2020 / PubMed / Full text
• Mitochondrial oxidative capacity and NAD biosynthesis are reduced in human sarcopenia across ethnicities. / 20.12.2019 / PubMed / Full text
• MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities. / 22.08.2019 / PubMed / Full text
• Constitutive PGC-1α overexpression in skeletal muscle does not protect from age-dependent decline in neurogenesis. / 23.08.2019 / PubMed / Full text

CD28

• Premature CD4 T Cells Senescence Induced by Chronic Infection in Patients with Acute Coronary Syndrome. / 12.2020 / PubMed / Full text
• The IMMENSE Study: The Interplay Between iMMune and ENdothelial Cells in Mediating Cardiovascular Risk in Systemic Lupus Erythematosus. / 2020 / PubMed / Full text
• Emergence of T cell immunosenescence in diabetic chronic kidney disease. / 2020 / PubMed / Full text
• The relationship between Chlamydia pneumoniae infection and CD4/CD8 ratio, lymphocyte subsets in middle-aged and elderly individuals. / 12.2020 / PubMed / Full text
• Next steps in mechanisms of inflammaging. / 22.09.2020 / PubMed / Full text
• A randomized pilot trial to evaluate the benefit of the concomitant use of atorvastatin and Raltegravir on immunological markers in protease-inhibitor-treated subjects living with HIV. / 2020 / PubMed / Full text
• Aging affects responsiveness of peripheral blood mononuclear cells to immunosuppression of periodontal ligament stem cells. / 07.2020 / PubMed / Full text
• Comparison of Donepezil, Memantine, Melatonin, and Liuwei Dihuang Decoction on Behavioral and Immune Endocrine Responses of Aged Senescence-Accelerated Mouse Resistant 1 Mice. / 2020 / PubMed / Full text
• Immunosenescent characteristics of T cells in young patients following haploidentical haematopoietic stem cell transplantation from parental donors. / 04.2020 / PubMed / Full text
• Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection. / 07.2020 / PubMed / Full text
• Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression. / 2020 / PubMed / Full text
• Accelerated immune aging was correlated with lupus-associated brain fog in reproductive-age systemic lupus erythematosus patients. / 05.2020 / PubMed / Full text
• T cells, aging and senescence. / 22.02.2020 / PubMed / Full text
• Liver fibrosis and accelerated immune dysfunction (immunosenescence) among HIV-infected Russians with heavy alcohol consumption - an observational cross-sectional study. / 31.12.2019 / PubMed / Full text
• Effect of Allogenic Bone Marrow Mesenchymal Stem Cell Transplantation on T Cells of Old Mice. / 02.2020 / PubMed / Full text
• Peripheral antibody concentrations are associated with highly differentiated T cells and inflammatory processes in the human bone marrow. / 2019 / PubMed / Full text

HGS

• Handgrip strength asymmetry is associated with future falls in older Americans. / 27.11.2020 / PubMed / Full text
• Examining Additional Aspects of Muscle Function with a Digital Handgrip Dynamometer and Accelerometer in Older Adults: A Pilot Study. / 31.10.2020 / PubMed / Full text
• The Relationship between Muscular Strength and Depression in Older Adults with Chronic Disease Comorbidity. / 18.09.2020 / PubMed / Full text
• Handgrip Strength in the Korean Population: Normative Data and Cutoff Values. / 12.2019 / PubMed / Full text
• Handgrip Strength Asymmetry and Weakness Are Associated with Lower Cognitive Function: A Panel Study. / 09.2020 / PubMed / Full text
• Handgrip Strength Asymmetry and Weakness are Differentially Associated with Functional Limitations in Older Americans. / 06.05.2020 / PubMed / Full text
• Absolute and Body Mass Index Normalized Handgrip Strength Percentiles by Gender, Ethnicity, and Hand Dominance in Americans. / 2020 / PubMed / Full text
• Hand grip strength variability during serial testing as an entropic biomarker of aging: a Poincaré plot analysis. / 13.01.2020 / PubMed / Full text
• Physical Activity and Fitness in White- and Blue-Collar Retired Men. / 11-12.2019 / PubMed / Full text
• Association between Hand Grip Strength and Self-Rated Health in Middle- and Old-Aged Korean Citizens. / 01.2020 / PubMed / Full text
• Weakness May Have a Causal Association With Early Mortality in Older Americans: A Matched Cohort Analysis. / 05.2020 / PubMed / Full text
• Associations Between Dietary Patterns and Handgrip Strength: The Korea National Health and Nutrition Examination Survey 2014-2016. / 08.2020 / PubMed / Full text
• Effect of relative handgrip strength on cardiovascular disease among Korean adults aged 45 years and older: Results from the Korean Longitudinal Study of Aging (2006-2016). / 01-02.2020 / PubMed / Full text
• Weakness and cognitive impairment are independently and jointly associated with functional decline in aging Americans. / 09.2020 / PubMed / Full text
• Association of phase angle with sarcopenia and its components in physically active older women. / 08.2020 / PubMed / Full text

CS

• Acute effect of bodyweight-based strength training on blood pressure of hypertensive older adults: A randomized crossover clinical trial. / 16.11.2020 / PubMed / Full text
• Particle growth with photochemical age from new particle formation to haze in the winter of Beijing, China. / 20.01.2021 / PubMed / Full text
• Effect of aging on stabilization of Cd and Ni by biochars and enzyme activities in a historically contaminated alkaline agricultural soil simulated with wet-dry and freeze-thaw cycling. / 27.10.2020 / PubMed / Full text
• Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD signaling. / 09.11.2020 / PubMed / Full text
• Vision Impairment and Participation in Cognitively Stimulating Activities: The Health ABC Study. / 25.07.2020 / PubMed / Full text
• Suspension training vs. traditional resistance training: effects on muscle mass, strength and functional performance in older adults. / 10.2020 / PubMed / Full text
• Generational Differences in the 10-year Incidence of Impaired Contrast Sensitivity. / 21.07.2020 / PubMed / Full text
• Inducible aging in Hydra oligactis implicates sexual reproduction, loss of stem cells, and genome maintenance as major pathways. / 08.2020 / PubMed / Full text
• Noradrenergic Responsiveness Supports Selective Attention across the Adult Lifespan. / 27.05.2020 / PubMed / Full text
• Cellular senescence: from anti-cancer weapon to anti-aging target. / 03.2020 / PubMed / Full text
• Extra-mitochondrial citrate synthase initiates calcium oscillation and suppresses age-dependent sperm dysfunction. / 04.2020 / PubMed / Full text
• Pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoke. / 10.2019 / PubMed / Full text
• Possible Role of Amyloid Cross-Seeding in Evolvability and Neurodegenerative Disease. / 2019 / PubMed / Full text
• Targeting p16-induced senescence prevents cigarette smoke-induced emphysema by promoting IGF1/Akt1 signaling in mice. / 2019 / PubMed / Full text

ACE2

• How Does SARS-CoV-2 Affect the Central Nervous System? A Working Hypothesis. / 2020 / PubMed / Full text
• Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2. / 2020 / PubMed / Full text
• A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. / 10.2020 / PubMed / Full text
• COVID-19 and Senotherapeutics: Any Role for the Naturally-occurring Dipeptide Carnosine? / 07.2020 / PubMed / Full text
• The dual impact of ACE2 in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions. / 15.09.2020 / PubMed / Full text
• The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of "inflame-aging". / 09.2020 / PubMed / Full text
• Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis. / 01.08.2020 / PubMed / Full text
• A Mouse Model of SARS-CoV-2 Infection and Pathogenesis. / 08.07.2020 / PubMed / Full text
• COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches. / 08.2020 / PubMed / Full text
• Gut microbiota and Covid-19- possible link and implications. / 08.2020 / PubMed / Full text
• Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes. / 06.2020 / PubMed / Full text
• Restoration of the Renin-Angiotensin System Balance Is a Part of the Effect of Fasting on Cardiovascular Rejuvenation: Role of Age and Fasting Models. / 08.2020 / PubMed / Full text
• Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in ACE2-knockout mice. / 30.09.2019 / PubMed / Full text

STAT3

• Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice. / 09.2020 / PubMed / Full text
• Skeletal glucocorticoid signalling determines leptin resistance and obesity in aging mice. / 12.2020 / PubMed / Full text
• AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF-κB/STAT3 axis-mediated positive feedback loop. / 10.2020 / PubMed / Full text
• Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation. / 08.09.2020 / PubMed / Full text
• Cell Death by Gallotannin Is Associated with Inhibition of the JAK/STAT Pathway in Human Colon Cancer Cells. / 2020 / PubMed / Full text
• The effect of interleukin 6 deficiency on myocardial signal transduction pathways activation induced by bacterial lipopolysaccharide in young and old mice. / 09.2020 / PubMed / Full text
• Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients. / 07.06.2020 / PubMed / Full text
• Implication of JAK1/STAT3/SOCS3 Pathway in Aging of Cerebellum of Male Rat: Histological and Molecular study. / 01.06.2020 / PubMed / Full text
• Atorvastatin-induced senescence of hepatocellular carcinoma is mediated by downregulation of hTERT through the suppression of the IL-6/STAT3 pathway. / 2020 / PubMed / Full text
• Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells. / 27.01.2020 / PubMed / Full text
• Persistent Activation of STAT3 Pathway in the Retina Induced Vision Impairment and Retinal Degenerative Changes in Ageing Mice. / 2019 / PubMed / Full text
• Interleukin-10 induces senescence of activated hepatic stellate cells via STAT3-p53 pathway to attenuate liver fibrosis. / 02.2020 / PubMed / Full text

CP

• A Life Course Perspective on Growing Older With Cerebral Palsy. / 19.11.2020 / PubMed / Full text
• The molecular anatomy and functions of the choroid plexus in healthy and diseased brain. / 01.11.2020 / PubMed / Full text
• The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation. / 09.2020 / PubMed / Full text
• Model based strategies towards protein A resin lifetime optimization and supervision. / 16.08.2020 / PubMed / Full text
• The influence of age and environmental conditions on supplement intake by beef cattle winter grazing northern mixed-grass rangelands. / 01.07.2020 / PubMed / Full text
• Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in mice. / 15.06.2020 / PubMed / Full text
• Asymptomatic [i]Clostridium perfringens[/i] Inhabitation in Intestine Can Cause Inflammation, Apoptosis, and Disorders in Brain. / 01.2020 / PubMed / Full text
• The Role of the Clinical Pharmacist in the Management of People Living with HIV in the Modern Antiretroviral Era. / 2019 / PubMed / Full text
• A clinically feasible method for the assessment and characterization of pain in patients with chronic pancreatitis. / 01.2020 / PubMed / Full text
• Differences in geometric strength at the contralateral hip between men with hip fracture and non-fractured comparators. / 03.2020 / PubMed / Full text
• Factors associated with the number of clinical pharmacy recommendations: findings from an observational study in geriatric inpatients. / 23.10.2019 / PubMed / Full text
• Protection against oxidative stress and anti-aging effect in Drosophila of royal jelly-collagen peptide. / 01.2020 / PubMed / Full text

APP

• Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging. / 11.09.2020 / PubMed / Full text
• Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD. / 09.07.2020 / PubMed / Full text
• An agnostic reevaluation of the amyloid cascade hypothesis of Alzheimer's disease pathogenesis: The role of APP homeostasis. / 11.2020 / PubMed / Full text
• Transcriptomic profiling of microglia and astrocytes throughout aging. / 01.04.2020 / PubMed / Full text
• Platelets in Amyloidogenic Mice Are Activated and Invade the Brain. / 2020 / PubMed / Full text
• CHIP modulates APP-induced autophagy-dependent pathological symptoms in Drosophila. / 02.2020 / PubMed / Full text
• Studies on APP metabolism related to age-associated mitochondrial dysfunction in APP/PS1 transgenic mice. / 19.11.2019 / PubMed / Full text
• Intermittent Hypoxia-Hyperoxia Training Improves Cognitive Function and Decreases Circulating Biomarkers of Alzheimer's Disease in Patients with Mild Cognitive Impairment: A Pilot Study. / 30.10.2019 / PubMed / Full text
• The Implication of Androgens in the Presence of Protein Kinase C to Repair Alzheimer’s Disease-Induced Cognitive Dysfunction / 03.2020 / PubMed / Full text
• Modulation of Neural and Muscular Adaptation Processes During Resistance Training by Fish Protein Ingestions in Older Adults. / 17.04.2020 / PubMed / Full text
• Antipsychotic Polypharmacy in Older Adult Asian Patients With Schizophrenia: Research on Asian Psychotropic Prescription Pattern. / 11.2019 / PubMed / Full text
• A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in the brain of Down syndrome patients. / 12.2019 / PubMed / Full text

ATM

• SATMF Suppresses the Premature Senescence Phenotype of the ATM Loss-of-Function Mutant and Improves Its Fertility in [i]Arabidopsis[/i]. / 30.10.2020 / PubMed / Full text
• ATM mediated-p53 signaling pathway forms a novel axis for senescence control. / 11.2020 / PubMed / Full text
• Non-canonical ATM/MRN activities temporally define the senescence secretory program. / 05.10.2020 / PubMed / Full text
• ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging. / 22.03.2020 / PubMed / Full text
• ATM suppresses leaf senescence triggered by DNA double-strand break through epigenetic control of senescence-associated genes in Arabidopsis. / 07.2020 / PubMed / Full text
• Glioblastoma Cells Do Not Affect Axitinib-Dependent Senescence of HUVECs in a Transwell Coculture Model. / 21.02.2020 / PubMed / Full text
• Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate. / 03.2020 / PubMed / Full text
• BRCA-related ATM-mediated DNA double-strand break repair and ovarian aging. / 01.01.2020 / PubMed / Full text
• ATM Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy. / 2019 / PubMed / Full text
• SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress. / 12.2019 / PubMed / Full text
• LncRNA RP11-670E13.6, interacted with hnRNPH, delays cellular senescence by sponging microRNA-663a in UVB damaged dermal fibroblasts. / 23.08.2019 / PubMed / Full text
• Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase. / 10.2019 / PubMed / Full text

GFAP

• Immunohistological Detection of Active Satellite Cellsin Rat Dorsal Root Ganglia after Parenteral Administration of Lipopolysaccharide and during Aging. / 09.2020 / PubMed / Full text
• Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease. / 23.09.2020 / PubMed / Full text
• ApoE Genotype-Dependent Response to Antioxidant and Exercise Interventions on Brain Function. / 25.06.2020 / PubMed / Full text
• Age-Dependent Heterogeneity of Murine Olfactory Bulb Astrocytes. / 2020 / PubMed / Full text
• Neuroinflammation in Aged Brain: Impact of the Oral Administration of Ellagic Acid Microdispersion. / 21.05.2020 / PubMed / Full text
• Long-term treatment with spermidine increases health span of middle-aged Sprague-Dawley male rats. / 06.2020 / PubMed / Full text
• Meta-analysis of human prefrontal cortex reveals activation of GFAP and decline of synaptic transmission in the aging brain. / 05.03.2020 / PubMed / Full text
• Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA-mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain. / 09.2020 / PubMed / Full text
• Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy. / 12.02.2020 / PubMed / Full text
• Lipopolysaccharide exposure during late embryogenesis triggers and drives Alzheimer-like behavioral and neuropathological changes in CD-1 mice. / 03.2020 / PubMed / Full text
• Increased levels of Aβ42 decrease the lifespan of ob/ob mice with dysregulation of microglia and astrocytes. / 02.2020 / PubMed / Full text
• Selective brain neuronal and glial losses without changes in GFAP immunoreactivity: Young versus mature adult Wistar rats. / 09.2019 / PubMed / Full text

CGA

• Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric assessment: A planned interim analysis of a multicenter, phase II trial. / 04.11.2020 / PubMed / Full text
• The Protective Effect of Chlorogenic Acid on Vascular Senescence via the Nrf2/HO-1 Pathway. / 25.06.2020 / PubMed / Full text
• Association between comprehensive geriatric assessment and short-term outcomes among older adult patients with stroke: A nationwide retrospective cohort study using propensity score and instrumental variable methods. / 06.2020 / PubMed / Full text
• Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis. / 12.2020 / PubMed / Full text
• A Computerized Frailty Assessment Tool at Points-of-Care: Development of a Standalone Electronic Comprehensive Geriatric Assessment/Frailty Index (eFI-CGA). / 2020 / PubMed / Full text
• Allocating patients to geriatric medicine wards in a tertiary university hospital in England: A service evaluation of the Specialist Advice for the Frail Elderly (SAFE) team. / 09.2018 / PubMed / Full text
• Role of Frailty on Risk Stratification in Cardiac Surgery and Procedures. / 2020 / PubMed / Full text
• Developing an objective structured clinical examination in comprehensive geriatric assessment - A pilot study. / 05-08.2019 / PubMed / Full text
• How do doctors choose treatment for older gynecological cancer patients? A Japanese Gynecologic Oncology Group survey of gynecologic oncologists. / 04.2020 / PubMed / Full text
• Validation of the Pictorial Fit-Frail Scale in a memory clinic setting. / 09.2020 / PubMed / Full text
• Impact of Resolution of Hyponatremia on Neurocognitive and Motor Performance in Geriatric Patients. / 29.08.2019 / PubMed / Full text
• Health outcome of older hospitalized patients in internal medicine environments evaluated by Identification of Seniors at Risk (ISAR) screening and geriatric assessment. / 14.08.2019 / PubMed / Full text

TH

• Thyroid hormone signaling is associated with physical performance, muscle mass, and strength in a cohort of oldest-old: results from the Mugello study. / 21.11.2020 / PubMed / Full text
• Social Environment Ameliorates Behavioral and Immune Impairments in Tyrosine Hydroxylase Haploinsufficient Female Mice. / 09.08.2020 / PubMed / Full text
• Mechanism of thyroid hormone signaling in skeletal muscle of aging mice. / 27.07.2020 / PubMed / Full text
• Longitudinal changes in bone mineral density and trabecular bone score in Korean adults: a community-based prospective study. / 03.07.2020 / PubMed / Full text
• Quantitative proteomic profiling of the rat substantia nigra places glial fibrillary acidic protein at the hub of proteins dysregulated during aging: Implications for idiopathic Parkinson's disease. / 07.2020 / PubMed / Full text
• Withaferin-A Protects the Nigral Dopamine Neuron and Recovers Motor Activity in Aged Rats. / 2019 / PubMed / Full text
• Effects of physical activity on bone mineral density in older adults: Korea National Health and Nutrition Examination Survey, 2008-2011. / 26.10.2019 / PubMed / Full text
• Age-Related Resistance to Thyroid Hormone Action. / 11.2019 / PubMed / Full text
• Age-Dependent Changes in Glucose Homeostasis in Male Deiodinase Type 2 Knockout Zebrafish. / 01.11.2019 / PubMed / Full text
• Age effect on thyroid hormone brain response in male mice. / 12.2019 / PubMed / Full text
• Aging Is Associated with Low Thyroid State and Organ-Specific Sensitivity to Thyroxine. / 12.2019 / PubMed / Full text

SOD2

• Astaxanthin Counteracts Vascular Calcification In Vitro Through an Early Up-Regulation of SOD2 Based on a Transcriptomic Approach. / 12.11.2020 / PubMed / Full text
• Alginate Oligosaccharide Prevents against D-galactose-mediated Cataract in C57BL/6J Mice via Regulating Oxidative Stress and Antioxidant System. / 06.11.2020 / PubMed / Full text
• Protoflavones in melanoma therapy: Prooxidant and pro-senescence effect of protoapigenone and its synthetic alkyl derivative in A375 cells. / 01.11.2020 / PubMed / Full text
• Ginsenoside Rg1 protects against Sca-1 HSC/HPC cell aging by regulating the SIRT1-FOXO3 and SIRT3-SOD2 signaling pathways in a γ-ray irradiation-induced aging mice model. / 08.2020 / PubMed / Full text
• Almond Skin Extracts and Chlorogenic Acid Delay Chronological Aging and Enhanced Oxidative Stress Response in Yeast. / 28.05.2020 / PubMed / Full text
• Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish. / 19.05.2020 / PubMed / Full text
• Bioactive peptides derived from crimson snapper and in vivo anti-aging effects on fat diet-induced high fat Drosophila melanogaster. / 29.01.2020 / PubMed / Full text
• Ellagic acid prolongs the lifespan of Drosophila melanogaster. / 02.2020 / PubMed / Full text
• Chlorella vulgaris modulates the expression of senescence-associated genes in replicative senescence of human diploid fibroblasts. / 01.2020 / PubMed / Full text
• Age-Associated Changes in Antioxidants and Redox Proteins of Rat Heart. / 30.12.2019 / PubMed / Full text
• Impact of curcumin on replicative and chronological aging in the Saccharomyces cerevisiae yeast. / 02.2020 / PubMed / Full text

MB

• Probing menstrual bloodstain aging with fluorescence spectroscopy. / 13.11.2020 / PubMed / Full text
• Effect of physical exercise and medication on enhancing cognitive function in older adults with vascular risk. / 11.2020 / PubMed / Full text
• A novel indenone derivative selectively induces senescence in MDA-MB-231 (breast adenocarcinoma) cells. / 01.11.2020 / PubMed / Full text
• Improved Autophagic Flux in Escapers from Doxorubicin-Induced Senescence/Polyploidy of Breast Cancer Cells. / 24.08.2020 / PubMed / Full text
• Lifespan regulation in α/β posterior neurons of the fly mushroom bodies by Rab27. / 08.2020 / PubMed / Full text
• Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells. / 29.05.2020 / PubMed / Full text
• "Mitotic Slippage" and Extranuclear DNA in Cancer Chemoresistance: A Focus on Telomeres. / 16.04.2020 / PubMed / Full text
• Diversity of the Senescence Phenotype of Cancer Cells Treated with Chemotherapeutic Agents. / 23.11.2019 / PubMed / Full text
• Downregulation of the inflammatory network in senescent fibroblasts and aging tissues of the long-lived and cancer-resistant subterranean wild rodent, Spalax. / 01.2020 / PubMed / Full text
• Quantification of the health-status of the Dutch Labrador retriever population. / 01.11.2019 / PubMed / Full text
• Conjugated Physiological Resveratrol Metabolites Induce Senescence in Breast Cancer Cells: Role of p53/p21 and p16/Rb Pathways, and ABC Transporters. / 11.2019 / PubMed / Full text

PC

• Blended home-based exercise and dietary protein in community-dwelling older adults: a cluster randomized controlled trial. / 26.10.2020 / PubMed / Full text
• Right ventricular diastolic function in aging: a head-to-head comparison between phase-contrast MRI and Doppler echocardiography. / 27.09.2020 / PubMed / Full text
• Pulse Width and Implantable Pulse Generator Longevity in Pallidal Deep Brain Stimulation for Dystonia: A Population-Based Comparative Effectiveness Study. / 2020 / PubMed / Full text
• Gemcitabine plus nab-paclitaxel with initial dose reduction for older patients with advanced pancreatic cancer. / 20.06.2020 / PubMed / Full text
• Protective effects of 17-β-oestradiol and phytoestrogen on age-induced oxidative stress and inhibition of surfactant synthesis in rat type II pneumocytes. / 02.2021 / PubMed / Full text
• Pacing During 200-m Competitive Masters Swimming. / 07.2020 / PubMed / Full text
• Prostate cancer in Pennsylvania: The role of older age at diagnosis, aggressiveness, and environmental risk factors on treatment and mortality using data from the Pennsylvania Cancer Registry. / 05.2020 / PubMed / Full text
• Extracranial versus intracranial hydro-hemodynamics during aging: a PC-MRI pilot cross-sectional study. / 14.01.2020 / PubMed / Full text
• Age-specific health-related quality of life in disease-free long-term prostate cancer survivors versus male population controls-results from a population-based study. / 06.2020 / PubMed / Full text
• Cross-Linked Polyphenol-Based Drug Nano-Self-Assemblies Engineered to Blockade Prostate Cancer Senescence. / 23.10.2019 / PubMed / Full text
• An Immersive Virtual Reality Platform for Assessing Spatial Navigation Memory in Predementia Screening: Feasibility and Usability Study. / 03.09.2019 / PubMed / Full text

TLR4

• Age-Dependent Changes of Adipokine and Cytokine Secretion From Rat Adipose Tissue by Endogenous and Exogenous Toll-Like Receptor Agonists. / 2020 / PubMed / Full text
• Role of Toll Like Receptor 4 in Alzheimer's Disease. / 2020 / PubMed / Full text
• Commentary on Some Recent Theses Relevant to Combating Aging: August 2020. / 08.2020 / PubMed / Full text
• Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration. / 2020 / PubMed / Full text
• Chemerin facilitates intervertebral disc degeneration via TLR4 and CMKLR1 and activation of NF-kB signaling pathway. / 11.06.2020 / PubMed / Full text
• Toll-like receptor 4 differentially regulates adult hippocampal neurogenesis in an age- and sex-dependent manner. / 09.2020 / PubMed / Full text
• Aging-associated immunosenescence via alterations in splenic immune cell populations in rat. / 15.01.2020 / PubMed / Full text
• Leptin induces immunosenescence in human B cells. / 02.2020 / PubMed / Full text
• Genetic Variation in the Magnitude and Longevity of the IgG Subclass Response to a Diphtheria-Tetanus-Acellular Pertussis (DTaP) Vaccine in Mice. / 20.09.2019 / PubMed / Full text
• Rapamycin improves sevoflurane‑induced cognitive dysfunction in aged rats by mediating autophagy through the TLR4/MyD88/NF‑κB signaling pathway. / 10.2019 / PubMed / Full text

FEV

• Prediction of Lung Function in Adolescence Using Epigenetic Aging: A Machine Learning Approach. / 09.11.2020 / PubMed / Full text
• Effect of Age on the Efficacy and Safety of Once-Daily Single-Inhaler Triple Therapy Fluticasone Furoate/Umeclidinium/Vilanterol in Patients With Chronic Obstructive Pulmonary Disease: A Post Hoc Analysis of the IMPACT Trial. / 05.10.2020 / PubMed / Full text
• A comprehensive analysis of factors related to lung function in older adults: Cross-sectional findings from the Canadian Longitudinal Study on Aging. / 11.2020 / PubMed / Full text
• Risk factors associated with the detection of pulmonary emphysema in older asymptomatic respiratory subjects. / 09.06.2020 / PubMed / Full text
• Tiotropium Respimat Efficacy and Safety in Asthma: Relationship to Age. / 09.2020 / PubMed / Full text
• Current Bronchodilator Responsiveness Criteria Underestimate Asthma in Older Adults. / 08.2020 / PubMed / Full text
• Physical performances show conflicting associations in aged manual workers. / 10.02.2020 / PubMed / Full text
• FEV as a Standalone Spirometric Predictor and the Attributable Fraction for Death in Older Persons. / 02.2020 / PubMed / Full text
• An Individualized Prediction Model for Long-term Lung Function Trajectory and Risk of COPD in the General Population. / 03.2020 / PubMed / Full text
• Telomere length and lung function in a population-based cohort of children and mid-life adults. / 12.2019 / PubMed / Full text

LPA

• Ginseng gintonin, aging societies, and geriatric brain diseases. / 03.2021 / PubMed / Full text
• Late-life related subtypes of depression - a data-driven approach on cognitive domains and physical frailty. / 22.05.2020 / PubMed / Full text
• Does sedentary time increase in older adults in the days following participation in intense exercise? / 12.2020 / PubMed / Full text
• Association of Long-term Exposure to Elevated Lipoprotein(a) Levels With Parental Life Span, Chronic Disease-Free Survival, and Mortality Risk: A Mendelian Randomization Analysis. / 05.02.2020 / PubMed / Full text
• Elevated Autotaxin and LPA Levels During Chronic Viral Hepatitis and Hepatocellular Carcinoma Associate with Systemic Immune Activation. / 25.11.2019 / PubMed / Full text
• Lysophosphatidic acid receptor LPA prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome. / 01.2020 / PubMed / Full text
• Associations of Sedentary and Physically-Active Behaviors With Cognitive-Function Decline in Community-Dwelling Older Adults: Compositional Data Analysis From the NEIGE Study. / 05.11.2020 / PubMed / Full text
• Validation and comparison of two automated methods for quantifying brain white matter hyperintensities of presumed vascular origin. / 02.2020 / PubMed / Full text
• The Sedentary Time and Physical Activity Levels on Physical Fitness in the Elderly: A Comparative Cross Sectional Study. / 01.10.2019 / PubMed / Full text
• Light-Intensity Physical Activity in a Large Prospective Cohort of Older US Adults: A 21-Year Follow-Up of Mortality. / 2020 / PubMed / Full text

SIRT6

• Association between SIRT6 Methylation and Human Longevity in a Chinese Population. / 25.11.2020 / PubMed / Full text
• The SIRT6 activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells. / 08.2020 / PubMed / Full text
• Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva. / 10.2020 / PubMed / Full text
• Age-related epigenetic drift deregulates [i]SIRT6[/i] expression and affects its downstream genes in human peripheral blood mononuclear cells. / 12.2020 / PubMed / Full text
• Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators. / 07.08.2020 / PubMed / Full text
• Age-dependent role of SIRT6 in jawbone via regulating senescence and autophagy of bone marrow stromal cells. / 02.2020 / PubMed / Full text
• Mechanism of activation for the sirtuin 6 protein deacylase. / 31.01.2020 / PubMed / Full text
• Proteomics of Long-Lived Mammals. / 03.2020 / PubMed / Full text
• Sirtuins and SIRT6 in Carcinogenesis and in Diet. / 07.10.2019 / PubMed / Full text
• SIRT6-mediated transcriptional suppression of MALAT1 is a key mechanism for endothelial to mesenchymal transition. / 15.11.2019 / PubMed / Full text

AMH

• Beyond premature ovarian insufficiency: Staging reproductive aging in adolescent and young adult cancer survivors. / 03.11.2020 / PubMed / Full text
• Correlates and Timing of Reproductive Aging Transitions in a Global Cohort of Midlife Women With Human Immunodeficiency Virus: Insights From the REPRIEVE Trial. / 09.07.2020 / PubMed / Full text
• Epigenetic clock measuring age acceleration via DNA methylation levels in blood is associated with decreased oocyte yield. / 05.2020 / PubMed / Full text
• Modeling Variation in the Reproductive Lifespan of Female Adolescent and Young Adult Cancer Survivors Using AMH. / 01.08.2020 / PubMed / Full text
• Improving Prediction of Age at Menopause Using Multiple Anti-Müllerian Hormone Measurements: the Tehran Lipid-Glucose Study. / 01.05.2020 / PubMed / Full text
• Antimullerian Hormone and Impending Menopause in Late Reproductive Age: The Study of Women's Health Across the Nation. / 01.04.2020 / PubMed / Full text
• Basal characterization and in vitro differentiation of putative stem cells derived from the adult mouse ovary. / 01.2020 / PubMed / Full text
• Serum anti-Müllerian hormone concentration and follicle density throughout reproductive life and in different diseases-implications in fertility preservation. / 01.12.2019 / PubMed / Full text
• Associations Between Anti-Mullerian Hormone and Cardiometabolic Health in Reproductive Age Women Are Explained by Body Mass Index. / 01.01.2020 / PubMed / Full text
• Relationships between antral follicle count, blood serum concentration of anti-Müllerian hormone and fertility in mares. / 10.2019 / PubMed / Full text

ATR

• Bloodstain age estimation through infrared spectroscopy and Chemometric models. / 11.2020 / PubMed / Full text
• Artificial Intelligence and fourier-transform infrared spectroscopy for evaluating water-mediated degradation of lubricant oils. / 01.11.2020 / PubMed / Full text
• Senescence Induction by Combined Ionizing Radiation and DNA Damage Response Inhibitors in Head and Neck Squamous Cell Carcinoma Cells. / 01.09.2020 / PubMed / Full text
• Kinetics of thermal degradation and lifetime study of poly(vinylidene fluoride) (PVDF) subjected to bioethanol fuel accelerated aging. / 07.2020 / PubMed / Full text
• Supraphysiological protection from replication stress does not extend mammalian lifespan. / 06.04.2020 / PubMed / Full text
• Assessing the Retest Reliability of Prefrontal EEG Markers of Brain Rhythm Slowing in the Eyes-Closed Resting State. / 09.2020 / PubMed / Full text
• Effects of Hydrogen Peroxide and Sodium Hypochlorite Aging on Properties and Performance of Polyethersulfone Ultrafiltration Membrane. / 18.10.2019 / PubMed / Full text
• NF-κB signaling in skin aging. / 12.2019 / PubMed / Full text
• Development of a w/o emulsion using ionic liquid strategy for transdermal delivery of anti - aging component α - lipoic acid: Mechanism of different ionic liquids on skin retention and efficacy evaluation. / 01.01.2020 / PubMed / Full text
• Effect of Nitrogen-Doped Graphene Oxide on the Aging Behavior of Nitrile-Butadiene Rubber. / 10.10.2019 / PubMed / Full text

PTEN

• Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis. / 26.10.2020 / PubMed / Full text
• Alterations in Mitochondrial Dynamic-related Genes in the Peripheral Blood of Alzheimer's Disease Patients. / 2020 / PubMed / Full text
• Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells. / 10.08.2020 / PubMed / Full text
• The precursor of PI(3,4,5)P alleviates aging by activating daf-18(Pten) and independent of daf-16. / 08.09.2020 / PubMed / Full text
• Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis. / 15.09.2020 / PubMed / Full text
• Downregulation of PTEN mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy. / 05.2020 / PubMed / Full text
• miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1. / 12.03.2020 / PubMed / Full text
• Environmental Exposures and Asthma Development: Autophagy, Mitophagy, and Cellular Senescence. / 2019 / PubMed / Full text
• PTEN loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation. / 17.09.2019 / PubMed / Full text

CCK

• Senolytic agent Quercetin ameliorates intervertebral disc degeneration via the Nrf2/NF-κB axis. / 23.11.2020 / PubMed / Full text
• Astragalus improve aging bone marrow mesenchymal stem cells (BMSCs) vitality and osteogenesis through VD-FGF23-Klotho axis. / 2020 / PubMed / Full text
• Effects of Age on Acute Appetite-Related Responses to Whey-Protein Drinks, Including Energy Intake, Gastric Emptying, Blood Glucose, and Plasma Gut Hormone Concentrations-A Randomized Controlled Trial. / 06.04.2020 / PubMed / Full text
• Lactose induced redox-dependent senescence and activated Nrf2 pathway. / 2019 / PubMed / Full text
• Quercetin Suppresses the Progression of Atherosclerosis by Regulating MST1-Mediated Autophagy in ox-LDL-Induced RAW264.7 Macrophage Foam Cells. / 03.12.2019 / PubMed / Full text
• LncRNA AW112010 Promotes Mitochondrial Biogenesis and Hair Cell Survival: Implications for Age-Related Hearing Loss. / 2019 / PubMed / Full text
• Effects of age on feeding response: Focus on the rostral C1 neuron and its glucoregulatory proteins. / 01.2020 / PubMed / Full text
• Ser-Tyr and Asn-Ala, vasorelaxing dipeptides found by comprehensive screening, reduce blood pressure via different age-dependent mechanisms. / 04.11.2019 / PubMed / Full text
• Fisetin, via CKIP-1/REGγ, limits oxidized LDL-induced lipid accumulation and senescence in RAW264.7 macrophage-derived foam cells. / 15.12.2019 / PubMed / Full text

FGF21

• Differential effects of sulfur amino acid-restricted and low-calorie diets on gut microbiome profile and bile acid composition in male C57BL6/J mice. / 27.10.2020 / PubMed / Full text
• Relationship between physical activity and circulating fibroblast growth factor 21 in middle-aged and older adults. / 11.2020 / PubMed / Full text
• Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy. / 09.2020 / PubMed / Full text
• Mitochondria, immunosenescence and inflammaging: a role for mitokines? / 10.2020 / PubMed / Full text
• Age-at-onset-dependent effects of sulfur amino acid restriction on markers of growth and stress in male F344 rats. / 07.2020 / PubMed / Full text
• Fibroblast growth factor 21 prolongs lifespan and improves stress tolerance in the silkworm, [i]Bombyx mori[/i]. / 03.2020 / PubMed / Full text
• Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice. / 13.11.2019 / PubMed / Full text
• Fibroblast Growth Factor 21 Mediates the Associations between Exercise, Aging, and Glucose Regulation. / 02.2020 / PubMed / Full text
• Effects of Moderate Chronic Food Restriction on the Development of Postprandial Dyslipidemia with Ageing. / 10.08.2019 / PubMed / Full text

TG

• Inhibition of the alternative lengthening of telomeres pathway by subtelomeric sequences in Saccharomyces cerevisiae. / 12.2020 / PubMed / Full text
• E4orf1, an Adeno-viral protein, attenuates renal lipid accumulation in high fat fed mice: A novel approach to reduce a key risk factor for chronic kidney disease. / 10.2020 / PubMed / Full text
• Resistance exercise attenuates postprandial metabolic responses to a high-fat meal similarly in younger and older men. / 11.2020 / PubMed / Full text
• Aging-induced aberrant RAGE/PPARα axis promotes hepatic steatosis via dysfunctional mitochondrial β oxidation. / 10.2020 / PubMed / Full text
• Fenofibrate impairs liver function and structure more pronounced in old than young rats. / 27.08.2020 / PubMed / Full text
• Awareness of major cardiovascular risk factors and its relationship with markers of vascular aging: Data from the Brisighella Heart Study. / 09.06.2020 / PubMed / Full text
• Characterisation of the dynamic nature of lipids throughout the lifespan of genetically identical female and male Daphnia magna. / 27.03.2020 / PubMed / Full text
• Effects of laboratory biotic aging on the characteristics of biochar and its water-soluble organic products. / 15.01.2020 / PubMed / Full text
• Using Caenorhabditis elegans for Studying Trans- and Multi-Generational Effects of Toxicants. / 29.07.2019 / PubMed / Full text

CD34

• Comparing the Effect of TGF-β Receptor Inhibition on Human Perivascular Mesenchymal Stromal Cells Derived from Endometrium, Bone Marrow and Adipose Tissues. / 01.12.2020 / PubMed / Full text
• ACE2/ACE imbalance and impaired vasoreparative functions of stem/progenitor cells in aging. / 27.11.2020 / PubMed / Full text
• Innovative Mind-Body Intervention Day Easy Exercise Increases Peripheral Blood CD34 Cells in Adults. / 01-12.2020 / PubMed / Full text
• Human Thymic Involution and Aging in Humanized Mice. / 2020 / PubMed / Full text
• Coinhibition of activated p38 MAPKα and mTORC1 potentiates stemness maintenance of HSCs from SR1-expanded human cord blood CD34 cells via inhibition of senescence. / 12.2020 / PubMed / Full text
• Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype. / 09.2020 / PubMed / Full text
• Mesenchymal stem cells repair bone marrow damage of aging rats and regulate autophagy and aging genes. / 08.2020 / PubMed / Full text
• Immune cell extracellular vesicles and their mitochondrial content decline with ageing. / 2020 / PubMed / Full text
• Young and elderly oral squamous cell carcinoma patients present similar angiogenic profile and predominance of M2 macrophages: Comparative immunohistochemical study. / 12.2019 / PubMed / Full text

ACE

• Elite swimmers possess shorter telomeres than recreationally active controls. / 15.10.2020 / PubMed / Full text
• Coronavirus Disease-2019 Conundrum: RAS Blockade and Geriatric-Associated Neuropsychiatric Disorders. / 2020 / PubMed / Full text
• Pregnancy Protects Hyperandrogenemic Female Rats From Postmenopausal Hypertension. / 09.2020 / PubMed / Full text
• Heart failure is associated with accelerated age related metabolic bone disease. / 05.06.2020 / PubMed / Full text
• Management of heart failure: an Italian national survey on fellows/specialists in geriatrics. / 10.2020 / PubMed / Full text
• Angiotensin-Converting Enzyme (ACE) genetic variation and longevity in Peruvian older people: a cross-sectional study. / 05.2020 / PubMed / Full text
• COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection? / 30.03.2020 / PubMed / Full text
• [i]A[/i]ngiotensin Converting Enzyme Inhibitors [i]C[/i]ombined with [i]E[/i]xercise for Hypertensive [i]S[/i]eniors (The ACES Trial): Study Protocol of a Randomized Controlled Trial. / 2019 / PubMed / Full text
• Vascular age. / Winter.2020 / PubMed

DBP

• Do baseline blood pressure and type of exercise influence level of reduction induced by training in hypertensive older adults? A meta-analysis of controlled trials. / 15.10.2020 / PubMed / Full text
• Attenuated aortic blood pressure responses to metaboreflex activation in older adults with dynapenia. / 09.2020 / PubMed / Full text
• The Effect of Blood Pressure on Cognitive Performance. An 8-Year Follow-Up of the Tromsø Study, Comprising People Aged 45-74 Years. / 2020 / PubMed / Full text
• Low Diastolic Blood Pressure and Cognitive Decline in Korean Elderly People: The Korean Longitudinal Study on Cognitive Aging and Dementia. / 01.2020 / PubMed / Full text
• Diastolic Blood Pressure Is Associated With Regional White Matter Lesion Load: The Northern Manhattan Study. / 02.2020 / PubMed / Full text
• Orthostatic Hypotension and Novel Blood Pressure Associated Gene Variants in Older Adults: Data From the TILDA Study. / 15.10.2020 / PubMed / Full text
• Blood pressure and hypertension prevalence among oldest-old in China for 16 year: based on CLHLS. / 09.09.2019 / PubMed / Full text
• The age-related blood pressure trajectories from young-old adults to centenarians: A cohort study. / 01.12.2019 / PubMed / Full text

CAT

• Training improves the handling of inhaler devices and reduces the severity of symptoms in geriatric patients suffering from chronic-obstructive pulmonary disease. / 09.10.2020 / PubMed / Full text
• 7-chloro-4-(phenylselanyl) quinoline co-treatment prevent oxidative stress in diabetic-like phenotype induced by hyperglycidic diet in Drosophila melanogaster. / 01.2021 / PubMed / Full text
• Aging influences in the blood-brain barrier permeability and cerebral oxidative stress in sepsis. / 15.10.2020 / PubMed / Full text
• 2 -Deoxy - d-glucose at chronic low dose acts as a caloric restriction mimetic through a mitohormetic induction of ROS in the brain of accelerated senescence model of rat. / 09-10.2020 / PubMed / Full text
• Ceftriaxone improves senile neurocognition damages induced by D-galactose in mice. / 03.2020 / PubMed / Full text
• Ginsenoside Rg1 protects against d-galactose induced fatty liver disease in a mouse model via FOXO1 transcriptional factor. / 01.08.2020 / PubMed / Full text
• Effects of long-term intermittent versus chronic calorie restriction on oxidative stress in a mouse cancer model. / 12.2019 / PubMed / Full text
• The Toxicity of Nonaged and Aged Coated Silver Nanoparticles to Freshwater Alga Raphidocelis subcapitata. / 11.2019 / PubMed / Full text

AFM

• Photocatalytic aging process of Nano-TiO coated polypropylene microplastics: Combining atomic force microscopy and infrared spectroscopy (AFM-IR) for nanoscale chemical characterization. / 15.02.2021 / PubMed / Full text
• Nanoscale infrared, thermal and mechanical properties of aged microplastics revealed by an atomic force microscopy coupled with infrared spectroscopy (AFM-IR) technique. / 20.11.2020 / PubMed / Full text
• Detecting zeta potential of polydimethylsiloxane (PDMS) in electrolyte solutions with atomic force microscope. / 15.10.2020 / PubMed / Full text
• Recent Applications of Advanced Atomic Force Microscopy in Polymer Science: A Review. / 17.05.2020 / PubMed / Full text
• Active fractions of mannoproteins derived from yeast cell wall stimulate innate and acquired immunity of adult and elderly dogs. / 03.2020 / PubMed / Full text
• The Effect of Waste Engine Oil and Waste Polyethylene on UV Aging Resistance of Asphalt. / 06.03.2020 / PubMed / Full text
• Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans. / 25.02.2020 / PubMed / Full text
• Nanomechanical insights: Amyloid beta oligomer-induced senescent brain endothelial cells. / 01.12.2019 / PubMed / Full text

SIRT3

• SIRT3 protects endothelial cells from high glucose-induced senescence and dysfunction via the p53 pathway. / 05.11.2020 / PubMed / Full text
• Melatonin and Sirtuins in Buccal Epithelium: Potential Biomarkers of Aging and Age-Related Pathologies. / 30.10.2020 / PubMed / Full text
• [i]SIRT3[/i] Transfection of Aged Human Bone Marrow-Derived Mesenchymal Stem Cells Improves Cell Therapy-Mediated Myocardial Repair. / 28.04.2020 / PubMed / Full text
• 17β-estradiol inhibits H O -induced senescence in HUVEC cells through upregulating SIRT3 expression and promoting autophagy. / 10.2020 / PubMed / Full text
• CR6 interacting factor 1 deficiency induces premature senescence via SIRT3 inhibition in endothelial cells. / 04.2020 / PubMed / Full text
• Mitochondrial function in skeletal myofibers is controlled by a TRF2-SIRT3 axis over lifetime. / 03.2020 / PubMed / Full text
• Context-Dependent Roles for SIRT2 and SIRT3 in Tumor Development Upon Calorie Restriction or High Fat Diet. / 2019 / PubMed / Full text
• The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders. / 01.2020 / PubMed / Full text

PINK1

• Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in [i]C. elegans[/i]. / 09.09.2020 / PubMed / Full text
• Female mice are resilient to age-related decline of substantia nigra dopamine neuron firing parameters. / 11.2020 / PubMed / Full text
• Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration. / 09.2020 / PubMed / Full text
• SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy. / 18.07.2020 / PubMed / Full text
• Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster. / 23.09.2020 / PubMed / Full text
• Compression-induced senescence of nucleus pulposus cells by promoting mitophagy activation via the PINK1/PARKIN pathway. / 05.2020 / PubMed / Full text
• Doxorubicin-induced normal breast epithelial cellular aging and its related breast cancer growth through mitochondrial autophagy and oxidative stress mitigated by ginsenoside Rh2. / 07.2020 / PubMed / Full text
• Mitochondrial DNA heteroplasmy rises in substantial nigra of aged PINK1 KO mice. / 22.01.2020 / PubMed / Full text

AR

• Mechanisms of Androgen Receptor Agonist- and Antagonist-Mediated Cellular Senescence in Prostate Cancer. / 08.07.2020 / PubMed / Full text
• Interleukin-23 Represses the Level of Cell Senescence Induced by the Androgen Receptor Antagonists Enzalutamide and Darolutamide in Castration-Resistant Prostate Cancer Cells. / 08.2020 / PubMed / Full text
• A Landscape of Murine Long Non-Coding RNAs Reveals the Leading Transcriptome Alterations in Adipose Tissue during Aging. / 26.05.2020 / PubMed / Full text
• Senolytic compounds control a distinct fate of androgen receptor agonist- and antagonist-induced cellular senescent LNCaP prostate cancer cells. / 2020 / PubMed / Full text
• Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice. / 01.04.2020 / PubMed / Full text
• A jaboticaba extract prevents prostatic damage associated with aging and high-fat diet intake. / 26.02.2020 / PubMed / Full text
• Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip. / 10.2019 / PubMed / Full text

IL6

• Basic immunology may lead to translational therapeutic rationale: SARS-CoV-2 and rheumatic diseases. / 09.2020 / PubMed / Full text
• ATM-deficient neural precursors develop senescence phenotype with disturbances in autophagy. / 09.2020 / PubMed / Full text
• The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification. / 23.06.2020 / PubMed / Full text
• Impact of Influenza on Pneumococcal Vaccine Effectiveness during [i]Streptococcus pneumoniae[/i] Infection in Aged Murine Lung. / 11.06.2020 / PubMed / Full text
• Patterns of multi-domain cognitive aging in participants of the Long Life Family Study. / 10.2020 / PubMed / Full text
• Cholest-4,6-Dien-3-One Promote Epithelial-To-Mesenchymal Transition (EMT) in Biliary Tree Stem/Progenitor Cell Cultures In Vitro. / 15.11.2019 / PubMed / Full text
• Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival. / 12.2019 / PubMed / Full text

NHS

• Telomerase Activation to Reverse Immunosenescence in Elderly Patients With Acute Coronary Syndrome: Protocol for a Randomized Pilot Trial. / 23.09.2020 / PubMed / Full text
• Factors associated with COVID-19-related death using OpenSAFELY. / 08.2020 / PubMed / Full text
• Advanced ophthalmic nurse practitioners: the potential to improve outcomes for older people with cataracts. / 17.06.2020 / PubMed / Full text
• Patient Satisfaction in the Spanish National Health Service: Partial Least Squares Structural Equation Modeling. / 04.12.2019 / PubMed / Full text
• Heart failure with preserved ejection fraction (HFpEF) pathophysiology study (IDENTIFY-HF): does increased arterial stiffness associate with HFpEF, in addition to ageing and vascular effects of comorbidities? Rationale and design. / 19.11.2019 / PubMed / Full text
• Challenges to concordance: theories that explain variations in patient responses. / 02.10.2019 / PubMed / Full text
• Optimism is associated with exceptional longevity in 2 epidemiologic cohorts of men and women. / 10.09.2019 / PubMed / Full text

CAD

• Serum soluble Klotho is inversely related to coronary artery calcification assessed by intravascular ultrasound in patients with stable coronary artery disease. / 07.12.2020 / PubMed / Full text
• Shear bond strengths of aged and non-aged CAD/CAM materials after different surface treatments. / 10.2020 / PubMed / Full text
• Prediction of Early Postoperative Major Cardiac Events and In-Hospital Mortality in Elderly Hip Fracture Patients: The Role of Different Types of Preoperative Cardiac Abnormalities on Echocardiography Report. / 2020 / PubMed / Full text
• [Polymorbidity in elderly patients needing myocardial revascularization (a review article).] / 2019 / PubMed
• Fracture force of CAD/CAM resin composite crowns after in vitro aging. / 07.2020 / PubMed / Full text
• Clinical performance of chairside monolithic lithium disilicate glass-ceramic CAD-CAM crowns. / 11.2019 / PubMed / Full text
• Acute resveratrol supplementation in coronary artery disease: towards patient stratification. / 02.2020 / PubMed / Full text

SI

• Microarray Profiling Reveals Distinct Circulating miRNAs in Aged Male and Female Mice Subjected to Post-stroke Social Isolation. / 19.10.2020 / PubMed / Full text
• Is Heart Rate a Confounding Factor for Photoplethysmography Markers? A Systematic Review. / 10.04.2020 / PubMed / Full text
• Survival time after marked reduction in oral intake in terminally ill noncancer patients: A retrospective study. / 03.2020 / PubMed / Full text
• Adherence to Mediterranean diet moderates the association between multimorbidity and depressive symptoms in older adults. / 05-06.2020 / PubMed / Full text
• Loneliness, Social Isolation, and Objectively Measured Physical Activity in Rural-Living Older Adults. / 19.12.2019 / PubMed / Full text
• The associations between social support and negative social interaction with suicidal ideation in US Chinese older adults. / 25.10.2019 / PubMed / Full text
• Cell Senescence and Cerebral Small Vessel Disease in the Brains of People Aged 80 Years and Older. / 01.11.2019 / PubMed / Full text

TF

• A preliminary investigation of the contribution of different tenderness factors to beef loin, tri-tip and heel tenderness. / 12.2020 / PubMed / Full text
• The transcription factor ZmNAC126 accelerates leaf senescence downstream of the ethylene signalling pathway in maize. / 09.2020 / PubMed / Full text
• Extensive transcriptome changes during seasonal leaf senescence in field-grown black cottonwood (Populus trichocarpa Nisqually-1). / 20.04.2020 / PubMed / Full text
• Expression of Transferrin and Albumin in the Sperm-Storage Tubules of Japanese Quail and their Possible Involvement in Long-Term Sperm Storage. / 25.01.2020 / PubMed / Full text
• OsWRKY5 Promotes Rice Leaf Senescence via Senescence-Associated NAC and Abscisic Acid Biosynthesis Pathway. / 09.09.2019 / PubMed / Full text
• BrTCP7 Transcription Factor Is Associated with MeJA-Promoted Leaf Senescence by Activating the Expression of [i]BrOPR3[/i] and [i]BrRCCR[/i]. / 14.08.2019 / PubMed / Full text
• Activation of the Transcription of [i]BrGA20ox3[/i] by a BrTCP21 Transcription Factor Is Associated with Gibberellin-Delayed Leaf Senescence in Chinese Flowering Cabbage during Storage. / 08.08.2019 / PubMed / Full text

GDF11

• Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice. / 04.05.2020 / PubMed / Full text
• Anti-Aging Effects of GDF11 on Skin. / 09.04.2020 / PubMed / Full text
• Targeted Approach to Distinguish and Determine Absolute Levels of GDF8 and GDF11 in Mouse Serum. / 06.2020 / PubMed / Full text
• Growth differentiation factor 11 impairs titanium implant healing in the femur and leads to mandibular bone loss. / 09.2020 / PubMed / Full text
• Systemic GDF11 stimulates the secretion of adiponectin and induces a calorie restriction-like phenotype in aged mice. / 01.2020 / PubMed / Full text
• Circulating factors in young blood as potential therapeutic agents for age-related neurodegenerative and neurovascular diseases. / 11.2019 / PubMed / Full text
• Effects of Exercise Training on Growth and Differentiation Factor 11 Expression in Aged Mice. / 2019 / PubMed / Full text

SDS

• Semiautomatic morphometric analysis of skeletal muscle obtained by needle biopsy in older adults. / 12.2020 / PubMed / Full text
• Effects of late-onset dietary intake of salidroside on insulin/insulin-like growth factor-1 (IGF-1) signaling pathway of the annual fish Nothobranchius guentheri. / 17.08.2020 / PubMed / Full text
• Quantification of Insoluble Protein Aggregation in Caenorhabditis elegans during Aging with a Novel Data-Independent Acquisition Workflow. / 07.08.2020 / PubMed / Full text
• Skeletal Muscle Myofibrillar Protein Abundance Is Higher in Resistance-Trained Men, and Aging in the Absence of Training May Have an Opposite Effect. / 10.01.2020 / PubMed / Full text
• Characterization, evaluation of nutritional parameters of Radix isatidis protein and its antioxidant activity in D-galactose induced ageing mice. / 06.11.2019 / PubMed / Full text
• [Effects of silver nanoparticles on pupation, eclosion, life span, apoptosis and protein expression in Drosophila melanogaster]. / 10.2019 / PubMed / Full text
• Does an Age-Specific Treatment Program Augment the Efficacy of a Cognitive-Behavioral Weight Loss Program in Adolescence and Young Adulthood? Results from a Controlled Study. / 02.09.2019 / PubMed / Full text

DDT

• Prognostic Value of a Test of Central Auditory Function in Conversion from Mild Cognitive Impairment to Dementia. / 2020 / PubMed / Full text
• Uptake kinetics of four hydrophobic organic pollutants in the earthworm Eisenia andrei in aged laboratory-contaminated natural soils. / 01.04.2020 / PubMed / Full text
• Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish. / 03-04.2020 / PubMed / Full text
• Second generation effects of larval metal pollutant exposure on reproduction, longevity and insecticide tolerance in the major malaria vector Anopheles arabiensis (Diptera: Culicidae). / 07.01.2020 / PubMed / Full text
• Protective effect of Pedro-Ximénez must against p,p'-DDE-induced liver damages in aged Mus spretus mice. / 02.2020 / PubMed / Full text
• Low-dose endosulfan inhibits proliferation and induces senescence and pro-inflammatory cytokine production in human lymphocytes, preferentially impacting cytotoxic cells. / 12.2019 / PubMed / Full text

GDF15

• Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging. / 31.10.2020 / PubMed / Full text
• Growth differentiation factor 15 protects against the aging-mediated systemic inflammatory response in humans and mice. / 08.2020 / PubMed / Full text
• Analysis of Epigenetic Age Predictors in Pain-Related Conditions. / 2020 / PubMed / Full text
• GDF15 Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness. / 2020 / PubMed / Full text
• GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis. / 01.10.2019 / PubMed / Full text
• Senescence-associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15. / 12.2019 / PubMed / Full text

CD44

• Hyaluronan goes to great length. / 17.07.2020 / PubMed / Full text
• Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties. / 12.05.2020 / PubMed / Full text
• Maturity-dependent cartilage cell plasticity and sensitivity to external perturbation. / 06.2020 / PubMed / Full text
• Aged Mice Exhibit Severe Exacerbations of Dry Eye Disease with an Amplified Memory Th17 Cell Response. / 07.2020 / PubMed / Full text
• Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice. / 13.02.2020 / PubMed / Full text
• Defective induction of the proteasome associated with T-cell receptor signaling underlies T-cell senescence. / 12.2019 / PubMed / Full text

APC

• Differences between blacks and whites in well-being, beliefs, emotional states, behaviors and survival, 1978-2014. / 2020 / PubMed / Full text
• Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging. / 07.08.2020 / PubMed / Full text
• Burden of musculoskeletal disorders in Iran during 1990-2017: estimates from the Global Burden of Disease Study 2017. / 10.07.2020 / PubMed / Full text
• Fall-related mortality trends in older Japanese adults aged ≥65 years: a nationwide observational study. / 11.12.2019 / PubMed / Full text
• Stroke Mortality Rates and Trends in Romania, 1994-2017. / 12.2019 / PubMed / Full text
• A new approach to quantifying the EEG during walking: Initial evidence of gait related potentials and their changes with aging and dual tasking. / 15.10.2019 / PubMed / Full text

CCR2

• Hip Fracture Leads to Transitory Immune Imprint in Older Patients. / 2020 / PubMed / Full text
• The CC-chemokine receptor 2 is involved in the control of ovarian folliculogenesis and fertility lifespan in mice. / 09.2020 / PubMed / Full text
• Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity. / 08.2020 / PubMed / Full text
• Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction. / 26.03.2020 / PubMed / Full text
• Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by CCR2. / 02.2020 / PubMed / Full text
• Klotho-mediated targeting of CCL2 suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments. / 11.2019 / PubMed / Full text

PCNA

• Impairment of Pol β-related DNA Base-excision Repair Leads to Ovarian Aging in Mice. / 20.11.2020 / PubMed / Full text
• [Heat shock protein 90 (HSP90) in age-dependent changes in the number of fibroblasts in human skin.] / 2020 / PubMed
• A Higher Frequency Administration of the Nontoxic Cycloartane-Type Triterpene Argentatin A Improved Its Anti-Tumor Activity. / 14.04.2020 / PubMed / Full text
• [Mechanosensitive protein of Hippo regulatory pathway - transcription coactivator with PZD-binding motif (TAZ) in human skin during aging.] / 2019 / PubMed
• [Mechanosensitive Yes-associated protein in human skin during aging.] / 2019 / PubMed
• [Role of mechanosensitive protein Piezo1 in human age-dependent changes in the number of fibroblasts and blood vessels in human skin.] / 2019 / PubMed

EGF

• Acute, exercise-induced alterations in cytokines and chemokines in the blood distinguish physically active and sedentary aging. / 08.12.2020 / PubMed / Full text
• Proinflammation, profibrosis, and arterial aging. / 09.2020 / PubMed / Full text
• Hinokitiol induces cell death and inhibits epidermal growth factor-induced cell migration and signaling pathways in human cervical adenocarcinoma. / 09.2020 / PubMed / Full text
• Activation of epidermal growth factor receptor signaling mediates cellular senescence induced by certain pro-inflammatory cytokines. / 05.2020 / PubMed / Full text
• Insulin Signaling in Intestinal Stem and Progenitor Cells as an Important Determinant of Physiological and Metabolic Traits in [i]Drosophila[/i]. / 26.03.2020 / PubMed / Full text
• Different cellular properties and loss of nuclear signalling of porcine epidermal growth factor receptor with aging. / 01.05.2020 / PubMed / Full text

FOXO3

• The DNA methylation of FOXO3 and TP53 as a blood biomarker of late-onset asthma. / 09.12.2020 / PubMed / Full text
• FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16 increase. / 11.2020 / PubMed / Full text
• Astaxanthin as a Putative Geroprotector: Molecular Basis and Focus on Brain Aging. / 05.07.2020 / PubMed / Full text
• Inflamma-miR-21 Negatively Regulates Myogenesis during Ageing. / 23.04.2020 / PubMed / Full text
• Variable DNA methylation of aging-related genes is associated with male COPD. / 04.11.2019 / PubMed / Full text
• A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster. / 08.2019 / PubMed / Full text

ABR

• [Hidden hearing loss and early identification]. / 07.2020 / PubMed / Full text
• Aging But Not Age-Related Hearing Loss Dominates the Decrease of Parvalbumin Immunoreactivity in the Primary Auditory Cortex of Mice. / 05-06.2020 / PubMed / Full text
• Hearing loss through apoptosis of the spiral ganglion neurons in apolipoprotein E knockout mice fed with a western diet. / 12.03.2020 / PubMed / Full text
• Effects of enriched endogenous omega-3 fatty acids on age-related hearing loss in mice. / 26.11.2019 / PubMed / Full text
• Hearing impairment and associated morphological changes in pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice. / 10.10.2019 / PubMed / Full text
• Global nurse/midwife workforce and reproductive health through social ecology lens. / 09.2019 / PubMed / Full text

NGF

• Dietary fish hydrolysate supplementation containing n-3 LC-PUFAs and peptides prevents short-term memory and stress response deficits in aged mice. / 23.09.2020 / PubMed / Full text
• Imbalance of nerve growth factor metabolism in aging women with overactive bladder syndrome. / 01.09.2020 / PubMed / Full text
• Parity Attenuates Intraepithelial Corneal Sensory Nerve Loss in Female Mice. / 21.07.2020 / PubMed / Full text
• Cholinergic System and NGF Receptors: Insights from the Brain of the Short-Lived Fish [i]Nothobranchius furzeri[/i]. / 20.06.2020 / PubMed / Full text
• Retrograde axonal transport of BDNF and proNGF diminishes with age in basal forebrain cholinergic neurons. / 12.2019 / PubMed / Full text
• C-SH2 point mutation converts p85β regulatory subunit of phosphoinositide 3-kinase to an anti-aging gene. / 03.09.2019 / PubMed / Full text

CD38

• Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction. / 02.11.2020 / PubMed / Full text
• TNFRSF12A and CD38 Contribute to a Vicious Circle for Chronic Obstructive Pulmonary Disease by Engaging Senescence Pathways. / 2020 / PubMed / Full text
• Aging alters acetylation status in skeletal and cardiac muscles. / 06.2020 / PubMed / Full text
• CD38 in Neurodegeneration and Neuroinflammation. / 18.02.2020 / PubMed / Full text
• CD38, a Receptor with Multifunctional Activities: From Modulatory Functions on Regulatory Cell Subsets and Extracellular Vesicles, to a Target for Therapeutic Strategies. / 27.11.2019 / PubMed / Full text
• CD38 Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD /Sirt1 Signaling Pathway. / 2019 / PubMed / Full text

LMNA

• Metformin alters peripheral blood mononuclear cells (PBMC) senescence biomarkers gene expression in type 2 diabetic patients. / 01.2021 / PubMed / Full text
• Protein structural and mechanistic basis of progeroid laminopathies. / 16.08.2020 / PubMed / Full text
• Progerin Expression Induces Inflammation, Oxidative Stress and Senescence in Human Coronary Endothelial Cells. / 12.05.2020 / PubMed / Full text
• The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes. / 04.2020 / PubMed / Full text
• Pharmacotherapy to gene editing: potential therapeutic approaches for Hutchinson-Gilford progeria syndrome. / 04.2020 / PubMed / Full text
• Long term breeding of the Lmna G609G progeric mouse: Characterization of homozygous and heterozygous models. / 02.2020 / PubMed / Full text

IVD

• MicroRNAs in Intervertebral Disc Degeneration, Apoptosis, Inflammation, and Mechanobiology. / 20.05.2020 / PubMed / Full text
• A step-by-step protocol for isolation of murine nucleus pulposus cells. / 12.2019 / PubMed / Full text
• Caspase-3 knockout inhibits intervertebral disc degeneration related to injury but accelerates degeneration related to aging. / 18.12.2019 / PubMed / Full text
• Finite element and deformation analyses predict pattern of bone failure in loaded zebrafish spines. / 29.11.2019 / PubMed / Full text
• Improvement in determining the risk of damage to the human lumbar functional spinal unit considering age, height, weight and sex using a combination of FEM and RSM. / 02.2020 / PubMed / Full text
• In vivo contrast-enhanced microCT for the monitoring of mouse thoracic, lumbar, and coccygeal intervertebral discs. / 06.2019 / PubMed / Full text

H2AX

• Evaluation of GammaH2AX in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer's Disease in the AIBL Study of Ageing. / 06.08.2020 / PubMed / Full text
• Cisplatin-induced peripheral neuropathy is associated to neuronal senescence-like response. / 29.06.2020 / PubMed / Full text
• Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites. / 06.04.2020 / PubMed / Full text
• Do BRCA1 and BRCA2 gene mutation carriers have a reduced ovarian reserve? Protocol for a prospective observational study. / 25.11.2019 / PubMed / Full text
• Slower rates of accumulation of DNA damage in leukocytes correlate with longer lifespans across several species of birds and mammals. / 15.11.2019 / PubMed / Full text
• Phosphoproteomic analysis reveals plant DNA damage signalling pathways with a functional role for histone H2AX phosphorylation in plant growth under genotoxic stress. / 12.2019 / PubMed / Full text

MAPT

• Association of relative brain age with tobacco smoking, alcohol consumption, and genetic variants. / 30.01.2020 / PubMed / Full text
• A blood-based nutritional risk index explains cognitive enhancement and decline in the multidomain Alzheimer prevention trial. / 2019 / PubMed / Full text
• Longitudinal associations of physical activity levels with morphological and functional changes related with aging: The MAPT study. / 12.2019 / PubMed / Full text
• Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease. / 31.10.2019 / PubMed / Full text
• Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective. / 01.2020 / PubMed / Full text

WRN

• The Impact of Vitamin C on Different System Models of Werner Syndrome. / 17.11.2020 / PubMed / Full text
• WRN modulates translation by influencing nuclear mRNA export in HeLa cancer cells. / 14.10.2020 / PubMed / Full text
• MIB1-mediated degradation of WRN promotes cellular senescence in response to camptothecin treatment. / 09.2020 / PubMed / Full text
• A Case Report of Werner's Syndrome With a Novel Mutation From India. / 08.05.2020 / PubMed / Full text
• Evidence for premature aging in a Drosophila model of Werner syndrome. / 11.2019 / PubMed / Full text

TFEB

• A Novel Lipofuscin-detecting Marker of Senescence Relates With Hypoxia, Dysregulated Autophagy and With Poor Prognosis in Non-small-cell-lung Cancer. / 11-12.2020 / PubMed / Full text
• ESC-sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia. / 05.2020 / PubMed / Full text
• Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging. / 2020 / PubMed / Full text
• Polyamines reverse immune senescence via the translational control of autophagy. / 01.2020 / PubMed / Full text
• Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. / 03.10.2019 / PubMed / Full text

LBP

• Lipopolysaccharide binding protein is associated with CVD risk in older adults. / 08.09.2020 / PubMed / Full text
• Aging-related liver degeneration is associated with increased bacterial endotoxin and lipopolysaccharide binding protein levels. / 01.04.2020 / PubMed / Full text
• Biomarkers of leaky gut are related to inflammation and reduced physical function in older adults with cardiometabolic disease and mobility limitations. / 12.2019 / PubMed / Full text
• Needle-shaped amyloid deposition in rat mammary gland: evidence of a novel amyloid fibril protein. / 03.2020 / PubMed / Full text
• Effects of Lycium barbarum Polysaccharides on Health and Aging of [i]C. elegans[/i] Depend on [i]daf-12/daf-16[/i]. / 2019 / PubMed / Full text

FES

• An outpatient Tai Chi program: Effects on veterans' functional outcomes. / 26.11.2020 / PubMed / Full text
• Gait Function in Adults Aged 50 Years and Older With Spina Bifida. / 07.11.2020 / PubMed / Full text
• A Single Question as a Screening Tool to Assess Fear of Falling in Young-Old Community-Dwelling Persons. / 09.2020 / PubMed / Full text
• Fall-related efficacy is a useful and independent index to detect fall risk in Japanese community-dwelling older people: a 1-year longitudinal study. / 29.10.2019 / PubMed / Full text
• Investigating Changes in Real-time Conscious Postural Processing by Older Adults during Different Stance Positions Using Electroencephalography Coherence. / 10-12.2019 / PubMed / Full text

CORT

• Sex differences in body composition, metabolism-related hormones, and energy homeostasis during aging in Wistar rats. / 10.2020 / PubMed / Full text
• Effects of age and social isolation on murine hippocampal biochemistry and behavior. / 10.2020 / PubMed / Full text
• Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice. / 10.2020 / PubMed / Full text
• Sex- and age-dependent differences in the hormone and drinking responses to water deprivation. / 01.03.2020 / PubMed / Full text
• Ontogeny of the adrenocortical response in an extremely altricial bird. / 12.2019 / PubMed / Full text

CCS

• Frailty Significantly Associated with a Risk for Mid-term Outcomes in Elderly Chronic Coronary Syndrome Patients: a Prospective Study. / 01.12.2020 / PubMed / Full text
• Microbleeds and Medial Temporal Atrophy Determine Cognitive Trajectories in Normal Aging: A Longitudinal PET-MRI Study. / 2020 / PubMed / Full text
• Hippocampal Volume Loss, Brain Amyloid Accumulation, and APOE Status in Cognitively Intact Elderly Subjects. / 2019 / PubMed / Full text
• Amyloid Load, Hippocampal Volume Loss, and Diffusion Tensor Imaging Changes in Early Phases of Brain Aging. / 2019 / PubMed / Full text
• Lower bone mass is associated with subclinical atherosclerosis, endothelial dysfunction and carotid thickness in the very elderly. / 01.2020 / PubMed / Full text

FGF23

• Phosphate as a Pathogen of Arteriosclerosis and Aging. / 08.10.2020 / PubMed / Full text
• Plasma Soluble αKlotho, Serum Fibroblast Growth Factor 23, and Mobility Disability in Community-Dwelling Older Adults. / 01.05.2020 / PubMed / Full text
• Protective effect of Polygonatum sibiricum Polysaccharide on D-galactose-induced aging rats model. / 10.02.2020 / PubMed / Full text
• FGF23 expression is stimulated in transgenic α-Klotho longevity mouse model. / 05.12.2019 / PubMed / Full text
• Fibroblast growth factor 23 and symmetric dimethylarginine concentrations in geriatric cats. / 11.2019 / PubMed / Full text

CFI

• Psychosocial Resources for Hedonic Balance, Life Satisfaction and Happiness in the Elderly: A Path Analysis. / 06.08.2020 / PubMed / Full text
• Validity and Reliability of the Flourishing Scale in a Sample of Older Adults in Iran. / 2020 / PubMed / Full text
• The decision about retirement: A scale to describe representations and practices of medical doctors and nurses. / 07-08.2016 / PubMed / Full text
• Family versus intimate partners: Estimating who matters more for health in a 20-year longitudinal study. / 03.2020 / PubMed / Full text
• Adapting and validating the Rosenberg Self-Esteem Scale for elderly Spanish population. / 02.2020 / PubMed / Full text

TEC

• Vestibular function and cortical and sub-cortical alterations in an aging population. / 08.2020 / PubMed / Full text
• Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration. / 2020 / PubMed / Full text
• Postnatal Involution and Counter-Involution of the Thymus. / 2020 / PubMed / Full text
• Gender Disparity Impacts on Thymus Aging and LHRH Receptor Antagonist-Induced Thymic Reconstitution Following Chemotherapeutic Damage. / 2020 / PubMed / Full text
• Clonogenic Culture of Mouse Thymic Epithelial Cells. / 2019 / PubMed / Full text

EGFR

• Type I Collagen Aging Increases Expression and Activation of EGFR and Induces Resistance to Erlotinib in Lung Carcinoma in 3D Matrix Model. / 2020 / PubMed / Full text
• Comparative effectiveness and cost-effectiveness of three first-line EGFR-tyrosine kinase inhibitors: Analysis of real-world data in a tertiary hospital in Taiwan. / 2020 / PubMed / Full text
• An Optogenetic Method to Study Signal Transduction in Intestinal Stem Cell Homeostasis. / 01.05.2020 / PubMed / Full text
• Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. / 13.01.2020 / PubMed / Full text
• Association between EGFR mutation and ageing, history of pneumonia and gastroesophageal reflux disease among patients with advanced lung cancer. / 11.2019 / PubMed / Full text

F3

• A Comprehensive Analysis of Age and Gender Effects in European Portuguese Oral Vowels. / 05.12.2020 / PubMed / Full text
• Prenatal exposure to an environmentally relevant phthalate mixture accelerates biomarkers of reproductive aging in a multiple and transgenerational manner in female mice. / 28.10.2020 / PubMed / Full text
• Combining Frontal Transcranial Direct Current Stimulation With Walking Rehabilitation to Enhance Mobility and Executive Function: A Pilot Clinical Trial. / 18.08.2020 / PubMed / Full text
• Multigenerational exposure to TiO nanoparticles in soil stimulates stress resistance and longevity of survived C. elegans via activating insulin/IGF-like signaling. / 08.2020 / PubMed / Full text
• Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice. / 12.09.2019 / PubMed / Full text

ATG7

• Age-related impairment of autophagy in cervical motor neurons. / 05.12.2020 / PubMed / Full text
• Comprehensive Bioinformatics Identifies Key microRNA Players in ATG7-Deficient Lung Fibroblasts. / 09.06.2020 / PubMed / Full text
• Regulation of autophagy by DNA G-quadruplexes. / 18.05.2020 / PubMed / Full text
• ATG7 is essential for secretion of iron from ameloblasts and normal growth of murine incisors during aging. / 10.2020 / PubMed / Full text
• Enhancing Autophagy Diminishes Aberrant Ca Homeostasis and Arrhythmogenesis in Aging Rabbit Hearts. / 2019 / PubMed / Full text

F2

• Environmental risk assessment of glufosinate-resistant soybean by pollen-mediated gene flow under field conditions in the region of the genetic origin. / 17.10.2020 / PubMed / Full text
• Gestational arsenite exposure augments hepatic tumors of C3H mice by promoting senescence in F1 and F2 offspring via different pathways. / 01.12.2020 / PubMed / Full text
• Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone. / 01.07.2020 / PubMed / Full text
• Conclusions from a behavioral aging study on male and female F2 hybrid mice on age-related behavior, buoyancy in water-based tests, and an ethical method to assess lifespan. / 11.09.2019 / PubMed / Full text
• In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. / 2019 / PubMed / Full text

UCP1

• Muscle-dependent regulation of adipose tissue function in long-lived growth hormone-mutant mice. / 28.05.2020 / PubMed / Full text
• Lack of UCP1 stimulates fatty liver but mediates UCP1-independent action of beige fat to improve hyperlipidemia in Apoe knockout mice. / 01.07.2020 / PubMed / Full text
• Postnatal leptin surge is critical for the transient induction of the developmental beige adipocytes in mice. / 01.04.2020 / PubMed / Full text
• Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice. / 05.12.2019 / PubMed / Full text
• An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise. / 19.08.2019 / PubMed / Full text

CD68

• Insulin activates microglia and increases COX-2/IL-1β expression in young but not in aged hippocampus. / 15.08.2020 / PubMed / Full text
• Epigenetic modulation of macrophage polarization prevents lumbar disc degeneration. / 20.04.2020 / PubMed / Full text
• Cellular senescence in recurrent tonsillitis and tonsillar hypertrophy in children. / 06.2020 / PubMed / Full text
• Ginsenoside Rg1 supplementation clears senescence-associated β-galactosidase in exercising human skeletal muscle. / 10.2019 / PubMed / Full text
• Histopathological, immunohistochemical, and molecular studies for determination of wound age and vitality in rats. / 12.2019 / PubMed / Full text

DBI

• Quantifying cumulative anticholinergic and sedative drug load among US Medicare Beneficiaries. / 01.10.2020 / PubMed / Full text
• Drug Burden Index and Cognitive and Physical Function in Aged Care Residents: A Longitudinal Study. / 08.2020 / PubMed / Full text
• Using the Drug Burden Index to identify older adults at highest risk for medication-related falls. / 12.06.2020 / PubMed / Full text
• Impact of STEADI-Rx: A Community Pharmacy-Based Fall Prevention Intervention. / 08.2020 / PubMed / Full text

MOS

• Effect of mannan oligosaccharides on the microbiota and productivity parameters of Litopenaeus vannamei shrimp under intensive cultivation in Ecuador. / 17.02.2020 / PubMed / Full text
• Predictors of health-related quality of life among older adults living with HIV in Thailand: results from the baseline and follow-up surveys. / 23.12.2019 / PubMed / Full text
• Comparison of health-related quality of life between the Han and Yi ethnicity elderly in the Yi autonomous areas of Yunnan Province. / 25.11.2019 / PubMed / Full text
• Mannan oligosaccharide increases the growth performance, immunity and resistance capability against Vibro Parahemolyticus in juvenile abalone Haliotis discus hannai Ino. / 11.2019 / PubMed / Full text

RET

• Effects of resistance exercise training on redox homeostasis in older adults. A systematic review and meta-analysis. / 09.2020 / PubMed / Full text
• Effects of an 8-week resistance training intervention on plantar flexor muscle quality and functional capacity in older women: A randomised controlled trial. / 09.2020 / PubMed / Full text
• Resistance exercise training promotes fiber type-specific myonuclear adaptations in older adults. / 01.04.2020 / PubMed / Full text
• Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults. / 11.2019 / PubMed / Full text

MET

• Self-rated health in relation to fruit and vegetable consumption and physical activity among older cancer survivors. / 26.09.2020 / PubMed / Full text
• Leisure-time physical activity volume, intensity, and duration from mid- to late-life in U.S. subpopulations by race and sex. The Atherosclerosis Risk In Communities (ARIC) Study. / 13.03.2020 / PubMed / Full text
• Repressive H3K9me2 protects lifespan against the transgenerational burden of COMPASS activity in [i]C. elegans[/i]. / 09.12.2019 / PubMed / Full text
• Influence of Anthropometrics on Step-Rate Thresholds for Moderate and Vigorous Physical Activity in Older Adults: Scientific Modeling Study. / 13.12.2018 / PubMed / Full text

SFN

• The phytoprotective agent sulforaphane prevents inflammatory degenerative diseases and age-related pathologies via Nrf2-mediated hormesis. / 04.11.2020 / PubMed / Full text
• Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice. / 29.09.2020 / PubMed / Full text
• Sulforaphane controls the release of paracrine factors by keratinocytes and thus mitigates particulate matter-induced premature skin aging by suppressing melanogenesis and maintaining collagen homeostasis. / 10.2020 / PubMed / Full text
• Sulforaphane Inhibits Autophagy and Induces Exosome-Mediated Paracrine Senescence via Regulating mTOR/TFE3. / 07.2020 / PubMed / Full text

MFI

• The Influence of the Accelerated Aging Conditions on the Properties of Polyolefin Geogrids Used for Landfill Slope Reinforcement. / 20.08.2020 / PubMed / Full text
• Changes in Physical Meat Traits, Protein Solubility, and the Microstructure of Different Beef Muscles during Post-Mortem Aging. / 19.06.2020 / PubMed / Full text
• Effect of a low-voltage electrical stimulation on yak meat tenderness during postmortem aging. / 01-12.2020 / PubMed / Full text
• Comparative effects of dry-aging and wet-aging on physicochemical properties and digestibility of Hanwoo beef. / 03.2020 / PubMed / Full text

CD27

• The Interplay between CD27 and CD27 B Cells Ensures the Flexibility, Stability, and Resilience of Human B Cell Memory. / 03.03.2020 / PubMed / Full text
• CMV-independent increase in CD27-CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians. / 2020 / PubMed / Full text
• Compartmentalized cytotoxic immune response leads to distinct pathogenic roles of natural killer and senescent CD8 T cells in human cutaneous leishmaniasis. / 04.2020 / PubMed / Full text
• CD27- IgD- B cell memory subset associates with inflammation and frailty in elderly individuals but only in males. / 2019 / PubMed / Full text

TP53

• p53 inhibits the osteogenic differentiation but does not induce senescence in human dental follicle cells. / 07-08.2020 / PubMed / Full text
• Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals. / 02.04.2020 / PubMed / Full text
• TP53/miR-34a-associated signaling targets [i]SERPINE1[/i] expression in human pancreatic cancer. / 27.01.2020 / PubMed / Full text
• Expression of p16 in nodular fasciitis: an implication for self-limited and inflammatory nature of the lesion. / 2019 / PubMed / Full text

EZH2

• Linking gene expression and phenotypic changes in the developmental and evolutionary origins of osteosclerosis in the ribs of bowhead whales (Balaena mysticetus). / 09.2020 / PubMed / Full text
• EZH2 is involved in vulnerability to neuroinflammation and depression-like behaviors induced by chronic stress in different aged mice. / 01.07.2020 / PubMed / Full text
• A positive feedback loop between EZH2 and NOX4 regulates nucleus pulposus cell senescence in age-related intervertebral disc degeneration. / 2020 / PubMed / Full text
• Perinatal exposure to bisphenol A impacts in the mammary gland morphology of adult Mongolian gerbils. / 04.2020 / PubMed / Full text

TET2

• Non-coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases. / 07.05.2020 / PubMed / Full text
• 60 Years of clonal hematopoiesis research: From X-chromosome inactivation studies to the identification of driver mutations. / 03.2020 / PubMed / Full text
• DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways. / 16.12.2019 / PubMed / Full text
• Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease. / 03.2020 / PubMed / Full text

JAK2

• Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity. / 2020 / PubMed / Full text
• Quercetin Directly Targets JAK2 and PKCδ and Prevents UV-Induced Photoaging in Human Skin. / 23.10.2019 / PubMed / Full text
• [Red blood cell lifespan detected by endogenous carbon monoxide breath test in patients with polycythemia vera]. / 01.10.2019 / PubMed / Full text
• Roles of JAK2 in Aging, Inflammation, Hematopoiesis and Malignant Transformation. / 08.08.2019 / PubMed / Full text

CD14

• Human innate immune cell crosstalk induces melanoma cell senescence. / 30.08.2020 / PubMed / Full text
• Fusion Potential of Human Osteoclasts In Vitro Reflects Age, Menopause, and In Vivo Bone Resorption Levels of Their Donors-A Possible Involvement of DC-STAMP. / 02.09.2020 / PubMed / Full text
• Association of CD14 with incident dementia and markers of brain aging and injury. / 21.01.2020 / PubMed / Full text
• Compromised Bone Healing in Aged Rats Is Associated With Impaired M2 Macrophage Function. / 2019 / PubMed / Full text

SHBG

• Endogenous Testosterone Levels and the Risk of Incident Cardiovascular Events in Elderly Men: The MrOS Prospective Study. / 01.05.2020 / PubMed / Full text
• Associations of Endogenous Sex Hormones with Carotid Plaque Burden and Characteristics in Midlife Women. / 01.04.2020 / PubMed / Full text
• Analysis of the Relationship between the Levels of Androgens and Biochemical Bone Markers in Men Aged 60-75 Years. / 22.12.2019 / PubMed / Full text
• Testosterone and Estrone Increase From the Age of 70 Years: Findings From the Sex Hormones in Older Women Study. / 01.12.2019 / PubMed / Full text

TST

• H S Donors Reverse Age-Related Gastric Malfunction Impaired Due to Fructose-Induced Injury [i]via[/i] CBS, CSE, and TST Expression. / 2020 / PubMed / Full text
• Adaptations in mechanical muscle function, muscle morphology, and aerobic power to high-intensity endurance training combined with either traditional or power strength training in older adults: a randomized clinical trial. / 05.2020 / PubMed / Full text
• Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging. / 2019 / PubMed / Full text
• Objective Sleep Duration in Older Adults: Results From The Irish Longitudinal Study on Ageing. / 01.2020 / PubMed / Full text

MIP

• Inspiratory muscle training improves cerebrovascular and postural control responses during orthostatic stress in older women. / 10.2020 / PubMed / Full text
• A novel multi-marker discovery approach identifies new serum biomarkers for Parkinson's disease in older people: an EXosomes in PArkiNson Disease (EXPAND) ancillary study. / 10.2020 / PubMed / Full text
• Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning. / 08.2020 / PubMed / Full text
• Comparison of balance changes after inspiratory muscle or Otago exercise training. / 2020 / PubMed / Full text

ATF6

• Cellular proteostasis decline in human senescence. / 30.11.2020 / PubMed / Full text
• Impact of endoplasmic reticulum stress on oocyte aging mechanisms. / 01.08.2020 / PubMed / Full text
• ER stress activates immunosuppressive network: implications for aging and Alzheimer's disease. / 05.2020 / PubMed / Full text
• Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes. / 21.01.2020 / PubMed / Full text

S100A9

• Cigarette smoke induction of S100A9 contributes to chronic obstructive pulmonary disease. / 23.09.2020 / PubMed / Full text
• Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations. / 2020 / PubMed / Full text
• Cellular senescence induced by S100A9 in mesenchymal stromal cells through NLRP3 inflammasome activation. / 14.11.2019 / PubMed / Full text
• S100A9 extends lifespan in insulin deficiency. / 07.08.2019 / PubMed / Full text

TXNIP

• Panax notoginseng saponins attenuate neuroinflammation through TXNIP-mediated NLRP3 inflammasome activation in aging rats. / 10.11.2020 / PubMed / Full text
• Redox homeostasis and cell cycle activation mediate beta-cell mass expansion in aged, diabetes-prone mice under metabolic stress conditions: Role of thioredoxin-interacting protein (TXNIP). / 07.10.2020 / PubMed / Full text
• [Effect of diabetic induced thioredoxin interacting protein (TXNIP) on islet cell senescence]. / 03.2020 / PubMed / Full text
• PRMT5-TRIM21 interaction regulates the senescence of osteosarcoma cells by targeting the TXNIP/p21 axis. / 05.02.2020 / PubMed / Full text

LBR

• Lamin B receptor: role on chromatin structure, cellular senescence and possibly aging. / 31.07.2020 / PubMed / Full text
• The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers. / 03.2020 / PubMed / Full text
• The role of lamin B receptor in the regulation of senescence-associated secretory phenotype (SASP). / 01.05.2020 / PubMed / Full text
• Lamin B receptor plays a key role in cellular senescence induced by inhibition of the proteasome. / 11.12.2019 / PubMed / Full text

C3

• Inverse association between periumbilical fat and longevity mediated by complement C3 and cardiac structure. / 18.11.2020 / PubMed / Full text
• Complement C3 deficiency ameliorates aging related changes in the kidney. / 01.11.2020 / PubMed / Full text
• Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice. / 04.2020 / PubMed / Full text
• [Comparative analysis of experimental data about the effects of various polyphenols on lifespan and aging.] / 2019 / PubMed

LRRK2

• Accelerated telomere shortening independent of LRRK2 variants in Chinese patients with Parkinson's disease. / 29.10.2020 / PubMed / Full text
• The effect of LRRK2 loss-of-function variants in humans. / 06.2020 / PubMed / Full text
• Parkinson's disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging. / 19.02.2020 / PubMed / Full text
• Autophagy and LRRK2 in the Aging Brain. / 2019 / PubMed / Full text

HGF

• Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4 T cell subsets. / 19.11.2020 / PubMed / Full text
• Hepatocyte growth factor (HGF) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling pathways. / 31.07.2020 / PubMed / Full text
• Phenytoin sodium-ameliorated gingival fibroblast aging is associated with autophagy. / 10.2020 / PubMed / Full text
• Impaired integrin α /β -mediated hepatocyte growth factor release by stellate cells of the aged liver. / 04.2020 / PubMed / Full text

STS

• Delayed Impairment of Postural, Physical, and Muscular Functions Following Downhill Compared to Level Walking in Older People. / 2020 / PubMed / Full text
• Autophagy displays divergent roles during intermittent amino acid starvation and toxic stress-induced senescence in cultured skeletal muscle cells. / 06.10.2020 / PubMed / Full text
• The WRKY53 transcription factor enhances stilbene synthesis and disease resistance by interacting with MYB14 and MYB15 in Chinese wild grape. / 30.05.2020 / PubMed / Full text
• On the role of ageing and musculoskeletal pain on dynamic balance in manual workers. / 02.2020 / PubMed / Full text

CDK6

• Saturated Fatty Acids Promote Hepatocytic Senecence through Regulation of miR-34a/Cyclin-Dependent Kinase 6. / 24.09.2020 / PubMed / Full text
• Hepatoprotective effects of hydroxysafflor yellow A in D-galactose-treated aging mice. / 15.08.2020 / PubMed / Full text
• Anti-cell growth and anti-cancer stem cell activity of the CDK4/6 inhibitor palbociclib in breast cancer cells. / 05.2020 / PubMed / Full text
• Compromising the constitutive p16 expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence. / 04.2020 / PubMed / Full text

IGF1

• Genetic differences and longevity-related phenotypes influence lifespan and lifespan variation in a sex-specific manner in mice. / 11.2020 / PubMed / Full text
• 17α-estradiol modulates IGF1 and hepatic gene expression in a sex-specific manner. / 28.08.2020 / PubMed / Full text
• Pan-mammalian analysis of molecular constraints underlying extended lifespan. / 11.02.2020 / PubMed / Full text
• 17α-Estradiol promotes ovarian aging in growth hormone receptor knockout mice, but not wild-type littermates. / 01.2020 / PubMed / Full text

ERCC1

• Chronic Sildenafil Treatment Improves Vasomotor Function in a Mouse Model of Accelerated Aging. / 30.06.2020 / PubMed / Full text
• Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction. / 17.04.2020 / PubMed / Full text
• Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice. / 03.2020 / PubMed / Full text
• Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin. / 03.2020 / PubMed / Full text

FH

• Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study. / 2020 / PubMed / Full text
• Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia. / 07.2020 / PubMed / Full text
• Macroscopic hematuria as a risk factor for hypertension in ageing people with hemophilia and a family history of hypertension. / 02.2020 / PubMed / Full text
• LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis. / 2020 / PubMed / Full text

BRAF

• Conditional reprograming culture conditions facilitate growth of lower grade glioma models. / 01.12.2020 / PubMed / Full text
• Active notch protects MAPK activated melanoma cell lines from MEK inhibitor cobimetinib. / 14.11.2020 / PubMed / Full text
• Mitochondrial metabolic reprograming via BRAF inhibition ameliorates senescence. / 15.10.2019 / PubMed / Full text

ARC

• The Polymorphism rs2968 of [i]LSS[/i] Gene Confers Susceptibility to Age-Related Cataract. / 11.2020 / PubMed / Full text
• Decreased Anti-Müllerian hormone and Anti-Müllerian hormone receptor type 2 in hypothalami of old Japanese Black cows. / 19.08.2020 / PubMed / Full text
• Resveratrol delay the cataract formation against naphthalene-induced experimental cataract in the albino rats. / 01.2020 / PubMed / Full text

CPM

• Test-Retest Instability of Temporal Summation and Conditioned Pain Modulation Measures in Older Adults. / 21.10.2020 / PubMed / Full text
• Age does not affect sex effect of conditioned pain modulation of pressure and thermal pain across 2 conditioning stimuli. / 01-02.2020 / PubMed / Full text
• The Decline of Endogenous Pain Modulation With Aging: A Meta-Analysis of Temporal Summation and Conditioned Pain Modulation. / 05-06.2020 / PubMed / Full text

PAH

• Changes in light absorption by brown carbon in soot particles due to heterogeneous ozone aging in a smog chamber. / 11.2020 / PubMed / Full text
• Factors associated with pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc). / 09.2020 / PubMed / Full text
• Potentially Avoidable Hospitalization among Long-Term Care Insurance Beneficiaries with Dementia. / 09.2020 / PubMed / Full text

DNMT3A

• Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells. / 09.09.2020 / PubMed / Full text
• Collagens and DNA methyltransferases in mare endometrosis. / 09.2019 / PubMed / Full text
• Age-related clonal haemopoiesis is associated with increased epigenetic age. / 19.08.2019 / PubMed / Full text

TNC

• Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging. / 18.11.2020 / PubMed / Full text
• Tenascin-C expression controls the maturation of articular cartilage in mice. / 17.02.2020 / PubMed / Full text
• Effects of hydrothermal aging, thermal cycling, and water storage on the mechanical properties of a machinable resin-based composite containing nano-zirconia fillers. / 02.2020 / PubMed / Full text

NRAS

• Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor. / 10.2020 / PubMed / Full text
• STAT3 Relays a Differential Response to Melanoma-Associated [i]NRAS[/i] Mutations. / 02.01.2020 / PubMed / Full text
• Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study. / 08.11.2019 / PubMed / Full text

FABP3

• FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging. / 09.11.2020 / PubMed / Full text
• Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3. / 04.11.2020 / PubMed / Full text
• Myokines as biomarkers of frailty and cardiovascular disease risk in females. / 05.2020 / PubMed / Full text

IL10

• The beneficial effect of physical exercise on inflammatory makers in older individuals. / 06.06.2020 / PubMed / Full text
• Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14 , and TAU3 transcript expression and contribute to cognitive decline. / 10.2019 / PubMed / Full text
• Dietary Spray-Dried Porcine Plasma Prevents Cognitive Decline in Senescent Mice and Reduces Neuroinflammation and Oxidative Stress. / 01.02.2020 / PubMed / Full text

CD47

• Aging-associated changes in CD47 arrangement and interaction with thrombospondin-1 on red blood cells visualized by super-resolution imaging. / 10.2020 / PubMed / Full text
• CD47 Promotes Age-Associated Deterioration in Angiogenesis, Blood Flow and Glucose Homeostasis. / 15.07.2020 / PubMed / Full text
• Unique Spatial Immune Profiling in Pancreatic Ductal Adenocarcinoma with Enrichment of Exhausted and Senescent T Cells and Diffused CD47-SIRPα Expression. / 07.07.2020 / PubMed / Full text

IMPACT

• Load-dependent modulation of alpha oscillations during working memory encoding and retention in young and older adults. / 03.11.2020 / PubMed / Full text
• Using Video Telehealth to Deliver Patient-Centered Collaborative Care: The G-IMPACT Pilot. / 31.03.2020 / PubMed / Full text
• AGING, HEART RATE VARIABILITY AND METABOLIC IMPACT OF OBESITY. / 09.2019 / PubMed / Full text

STAT1

• STAT1-p53-p21axis-dependent stress-induced progression of chronic nephrosis in adriamycin-induced mouse model. / 08.2020 / PubMed / Full text
• Age-Dependent and -Independent Effects of Perivascular Adipose Tissue and Its Paracrine Activities during Neointima Formation. / 31.12.2019 / PubMed / Full text
• Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activation. / 01.03.2020 / PubMed / Full text

VDR

• 25-Hydroxyvitamin D positively regulates periodontal inflammaging via SOCS3/STAT signaling in diabetic mice. / 04.2020 / PubMed / Full text
• 1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel VDR-Ezh2-p16 signal axis. / 02.2020 / PubMed / Full text
• Active vitamin D impedes the progression of non-alcoholic fatty liver disease by inhibiting cell senescence in a rat model. / 09.2020 / PubMed / Full text

CA3

• Features of Postnatal Hippocampal Development in a Rat Model of Sporadic Alzheimer's Disease. / 2020 / PubMed / Full text
• Age-Related Changes in Synaptic Plasticity Associated with Mossy Fiber Terminal Integration during Adult Neurogenesis. / 05-06.2020 / PubMed / Full text
• Metabotropic Glutamate Receptors at the Aged Mossy Fiber - CA3 Synapse of the Hippocampus. / 07.01.2020 / PubMed / Full text

DMD

• Aldehyde dehydrogenases contribute to skeletal muscle homeostasis in healthy, aging, and Duchenne muscular dystrophy patients. / 08.2020 / PubMed / Full text
• Life expectancy at birth in Duchenne muscular dystrophy: a systematic review and meta-analysis. / 07.2020 / PubMed / Full text
• Renal dysfunction can occur in advanced-stage Duchenne muscular dystrophy. / 02.2020 / PubMed / Full text

MMD

• Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study. / 22.11.2020 / PubMed / Full text
• Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study. / 16.09.2020 / PubMed / Full text
• Impact and Lessons From the Lifestyle Interventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability. / 04.2020 / PubMed / Full text

HSF1

• A Mitochondrial Stress-Specific Form of HSF1 Protects against Age-Related Proteostasis Collapse. / 28.09.2020 / PubMed / Full text
• Heat shock factor 1-mediated transcription activation of Omi/HtrA2 induces myocardial mitochondrial apoptosis in the aging heart. / 18.10.2019 / PubMed / Full text
• Multifactorial Attenuation of the Murine Heat Shock Response With Age. / 25.09.2020 / PubMed / Full text

REST

• [Brain and Neuronal Aging: Aged Brain Controls via Gene Expression Fidelity and Master Regulatory Factors]. / 2020 / PubMed / Full text
• Effect of 9 - PAHSA on cognitive dysfunction in diabetic mice and its possible mechanism. / 09.04.2020 / PubMed / Full text
• Increased REST to Optimize Life Span? / 12.2019 / PubMed / Full text

LMNB1

• SIRT1 - a new mammalian substrate of nuclear autophagy. / 08.12.2020 / PubMed / Full text
• Cellular senescence as a response to multiwalled carbon nanotube (MWCNT) exposure in human mesothelial cells. / 03.12.2020 / PubMed / Full text
• Inflammatory Drivers of Cardiovascular Disease: Molecular Characterization of Senescent Coronary Vascular Smooth Muscle Cells. / 2020 / PubMed / Full text

ERF

• Angiotensin-Converting Enzyme Gene D/I Polymorphism in Relation to Endothelial Function and Endothelial-Released Factors in Chinese Women. / 2020 / PubMed / Full text
• Projections of Ambient Temperature- and Air Pollution-Related Mortality Burden Under Combined Climate Change and Population Aging Scenarios: a Review. / 09.2020 / PubMed / Full text
• Exome Sequencing Analysis Identifies Rare Variants in [i]ATM[/i] and [i]RPL8[/i] That Are Associated With Shorter Telomere Length. / 2020 / PubMed / Full text

PRL

• Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis. / 25.08.2020 / PubMed / Full text
• Prolactin mitigates deficiencies of retinal function associated with aging. / 01.2020 / PubMed / Full text
• A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation. / 06.08.2019 / PubMed / Full text

NEDD8

• Targeting Protein Neddylation for Cancer Therapy. / 2020 / PubMed / Full text
• Effective targeting of the ubiquitin-like modifier NEDD8 for lung adenocarcinoma treatment. / 08.2020 / PubMed / Full text
• Pevonedistat targeted therapy inhibits canine melanoma cell growth through induction of DNA re-replication and senescence. / 09.2020 / PubMed / Full text

EDA

• Interplay between aging, lung inflammation/remodeling, and fibronectin EDA in lung cancer progression. / 01.12.2020 / PubMed / Full text
• Arousal Detection in Elderly People from Electrodermal Activity Using Musical Stimuli. / 25.08.2020 / PubMed / Full text
• The structure of agricultural microplastics (PT, PU and UF) and their sorption capacities for PAHs and PHE derivates under various salinity and oxidation treatments. / 02.2020 / PubMed / Full text

PFAS

• Associations between serum concentrations of perfluoroalkyl substances and DNA methylation in women exposed through drinking water: A pilot study in Ronneby, Sweden. / 12.2020 / PubMed / Full text
• Perfluorinated alkyl substances impede growth, reproduction, lipid metabolism and lifespan in Daphnia magna. / 01.10.2020 / PubMed / Full text
• The effect of weathering on per- and polyfluoroalkyl substances (PFASs) from durable water repellent (DWR) clothing. / 06.2020 / PubMed / Full text

P2RY12

• Potential caveats of putative microglia-specific markers for assessment of age-related cerebrovascular neuroinflammation. / 01.12.2020 / PubMed / Full text
• Microglial changes in the early aging stage in a healthy retina and an experimental glaucoma model. / 2020 / PubMed / Full text
• Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains. / 20.01.2020 / PubMed / Full text

G6PD

• G6PD overexpression protects from oxidative stress and age-related hearing loss. / 22.11.2020 / PubMed / Full text
• The Sickle Effect: The Silent Titan Affecting Glycated Hemoglobin Reliability. / 12.08.2020 / PubMed / Full text
• DNA damage and synaptic and behavioural disorders in glucose-6-phosphate dehydrogenase-deficient mice. / 01.2020 / PubMed / Full text

C9

• C9orf72 in myeloid cells suppresses STING-induced inflammation. / 09.2020 / PubMed / Full text
• Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain. / 16.12.2019 / PubMed / Full text
• Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity. / 12.2019 / PubMed / Full text

CD81

• Ovarian aging increases small extracellular vesicle CD81 release in human follicular fluid and influences miRNA profiles. / 17.06.2020 / PubMed / Full text
• Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature. / 15.04.2020 / PubMed / Full text
• Increased production of functional small extracellular vesicles in senescent endothelial cells. / 04.2020 / PubMed / Full text

CTRL

• Aging reduces the maximal level of peripheral fatigue tolerable and impairs exercise capacity. / 01.12.2020 / PubMed / Full text
• miR-146a Plasma Levels Are Not Altered in Alzheimer's Disease but Correlate With Age and Illness Severity. / 2019 / PubMed / Full text
• Centrally-mediated regulation of peripheral fatigue during knee extensor exercise and consequences on the force-duration relationship in older men. / 06.2020 / PubMed / Full text

TREM2

• Loss of TREM2 Confers Resilience to Synaptic and Cognitive Impairment in Aged Mice. / 09.12.2020 / PubMed / Full text
• Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer's Disease Brain. / 2020 / PubMed / Full text
• Knockdown of astrocytic TREM2 in the hippocampus relieves cognitive decline in elderly male mice. / 15.01.2021 / PubMed / Full text

TPR

• Catalytic Performances of Cu/MCM-22 Zeolites with Different Cu Loadings in NH -SCR. / 30.10.2020 / PubMed / Full text
• Do traits of plant species predict the efficacy of species distribution models for finding new occurrences? / 06.2020 / PubMed / Full text
• In-situ modified the surface of Pt-doped perovskite catalyst for soot oxidation. / 05.02.2020 / PubMed / Full text

PAM

• Relationship between patient activation measurement and self-rated health in patients with chronic diseases. / 04.11.2020 / PubMed / Full text
• Reversal of Age-Related Neuronal Atrophy by α5-GABAA Receptor Positive Allosteric Modulation. / 17.10.2020 / PubMed / Full text
• The ratio of prematurely aging to non-prematurely aging mice cohabiting, conditions their behavior, immunity and lifespan. / 15.06.2020 / PubMed / Full text

CD36

• Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease. / 08.2020 / PubMed / Full text
• Reduction of senescence-associated beta-galactosidase activity by vitamin E in human fibroblasts depends on subjects' age and cell passage number. / 07.2020 / PubMed / Full text
• Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. / 05.2020 / PubMed / Full text

SOD1

• SOD1, more than just an antioxidant. / 28.11.2020 / PubMed / Full text
• The Exacerbation of Aging and Oxidative Stress in the Epididymis of [i]Sod1[/i] Null Mice. / 11.02.2020 / PubMed / Full text
• Alterations in lipid metabolism of spinal cord linked to amyotrophic lateral sclerosis. / 12.08.2019 / PubMed / Full text

MDM2

• SENEBLOC, a long non-coding RNA suppresses senescence via p53-dependent and independent mechanisms. / 06.04.2020 / PubMed / Full text
• Disruption of Robo2-Baiap2 integrated signaling drives cystic disease. / 19.09.2019 / PubMed / Full text
• Senescence-induced immunophenotype, gene expression and electrophysiology changes in human amniocytes. / 11.2019 / PubMed / Full text

CCN1

• Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis. / 09.2020 / PubMed / Full text
• Inhibition of cellular communication network factor 1 (CCN1)-driven senescence slows down cartilage inflammaging and osteoarthritis. / 10.2020 / PubMed / Full text
• The senescence-associated matricellular protein CCN1 in plasma of human subjects with idiopathic pulmonary fibrosis. / 01.2020 / PubMed / Full text

SOX2

• Multiple nanosecond pulsed electric fields stimulation with conductive poly(l-lactic acid)/carbon nanotubes films maintains the multipotency of mesenchymal stem cells during prolonged in vitro culture. / 08.2020 / PubMed / Full text
• Subpopulations of miniature pig mesenchymal stromal cells with different differentiation potentials differ in the expression of octamer-binding transcription factor 4 and sex determining region Y-box 2. / 03.2020 / PubMed / Full text
• Increased Type I and Decreased Type II Hair Cells after Deletion of Sox2 in the Developing Mouse Utricle. / 01.12.2019 / PubMed / Full text

MCC

• Multiple chronic conditions and risk of cognitive impairment and dementia among older Americans: findings from the Aging, Demographics, and Memory Study (ADAMS). / 07.07.2020 / PubMed / Full text
• Behaviour consistency is a sensitive tool for distinguishing the effects of aging on physical activity. / 01.07.2020 / PubMed / Full text
• Burden on Caregivers of Adults with Multiple Chronic Conditions: Intersectionality of Age, Gender, Education level, Employment Status, and Impact on Social Life. / 09.2020 / PubMed / Full text

ARNT

• Loss of ARNT in skeletal muscle limits muscle regeneration in aging. / 12.2020 / PubMed / Full text
• [Arylhydrocarbon receptor nuclear translocator (ARNT) in human skin during aging.] / 2020 / PubMed
• The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1. / 03.04.2020 / PubMed / Full text

NAMPT

• Over-expression of Nicotinamide phosphoribosyltransferase in mouse cells confers protective effect against oxidative and ER stress-induced premature senescence. / 08.2020 / PubMed / Full text
• Resistance training increases muscle NAD and NADH concentrations as well as NAMPT protein levels and global sirtuin activity in middle-aged, overweight, untrained individuals. / 05.05.2020 / PubMed / Full text
• Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase (NAMPT) and Sirtuin-1 (SIRT-1) Pathway in Obesity and T2DM: Modulation by Metformin and Macronutrient Intake. / 2019 / PubMed / Full text

CXCR4

• Aging-Related Reduced Expression of CXCR4 on Bone Marrow Mesenchymal Stromal Cells Contributes to Hematopoietic Stem and Progenitor Cell Defects. / 08.2020 / PubMed / Full text
• Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway. / 09.2020 / PubMed / Full text
• Stromal Cell-Derived Factor 1 Protects Brain Vascular Endothelial Cells from Radiation-Induced Brain Damage. / 10.10.2019 / PubMed / Full text

MTOR

• The roles of MTOR and miRNAs in endothelial cell senescence. / 10.2020 / PubMed / Full text
• Autophagy drives fibroblast senescence through MTORC2 regulation. / 11.2020 / PubMed / Full text
• The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan. / 09.2020 / PubMed / Full text

BRD4

• Inhibition of BRD4 triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells. / 20.09.2020 / PubMed / Full text
• BRD4 contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake. / 11.05.2020 / PubMed / Full text
• BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes. / 26.09.2019 / PubMed / Full text

CXCL12

• Co-option of Neutrophil Fates by Tissue Environments. / 25.11.2020 / PubMed / Full text
• Heme oxygenase-1 deficiency triggers exhaustion of hematopoietic stem cells. / 05.02.2020 / PubMed / Full text
• Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation. / 03.12.2019 / PubMed / Full text

SLA

• Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity. / 14.07.2020 / PubMed / Full text
• Mechanical Anisotropy and Surface Roughness in Additively Manufactured Parts Fabricated by Stereolithography (SLA) Using Statistical Analysis. / 30.05.2020 / PubMed / Full text
• The Effect of Age of Titanium Dental Implants on Implant Survival and Marginal Bone Resorption: A 5-Year Retrospective Follow-Up Study. / 01.10.2020 / PubMed / Full text

ASL

• Increased blood-brain barrier permeability to water in the aging brain detected using noninvasive multi-TE ASL MRI. / 01.2021 / PubMed / Full text
• Quantitative Cerebrovascular Reactivity in Normal Aging: Comparison Between Phase-Contrast and Arterial Spin Labeling MRI. / 2020 / PubMed / Full text
• Correcting Task fMRI Signals for Variability in Baseline CBF Improves BOLD-Behavior Relationships: A Feasibility Study in an Aging Model. / 2020 / PubMed / Full text

DPP4

• Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis. / 2020 / PubMed / Full text
• Dipeptidyl peptidase-4 inhibition improves endothelial senescence by activating AMPK/SIRT1/Nrf2 signaling pathway. / 07.2020 / PubMed / Full text
• Molecular crosstalk between Y5 receptor and neuropeptide Y drives liver cancer. / 01.05.2020 / PubMed / Full text

CA2

• Maintaining Aging Hippocampal Function with Safe and Feasible Shaking Exercise in SAMP10 Mice. / 2020 / PubMed / Full text
• One-year Follow-up Study of Hippocampal Subfield Atrophy in Alzheimer's Disease and Normal Aging. / 2019 / PubMed / Full text
• Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory. / 29.10.2019 / PubMed / Full text

SST

• The distance to death perceptions of older adults explain why they age in place: A theoretical examination. / 09.2020 / PubMed / Full text
• Population Segmentation Based on Healthcare Needs: Validation of a Brief Clinician-Administered Tool. / 30.06.2020 / PubMed / Full text
• Examination on how emotion regulation mediates the relationship between future time perspective and well-being: a counter-evidence to the socioemotional selectivity theory. / 03.2020 / PubMed / Full text

GRK2

• G protein-coupled receptor kinase 2 modifies the ability of Caenorhabditis elegans to survive oxidative stress. / 16.10.2020 / PubMed / Full text
• G protein coupled receptor kinases modulate Caenorhabditis elegans reactions to heat stresses. / 01.10.2020 / PubMed / Full text
• Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging. / 01.05.2020 / PubMed / Full text

AIP

• [Aryl hydrocarbon receptor interacting protein (AIP) in human dermis during aging.] / 2020 / PubMed
• Sex-Specific Association between Serum Vitamin D Status and Lipid Profiles: A Cross-Sectional Study of a Middle-Aged and Elderly Chinese Population. / 2020 / PubMed / Full text
• The oblique effect: The relationship between profiles of visuospatial preference, cognition, and brain connectomics in older adults. / 12.2019 / PubMed / Full text

PSD

• Quantitative Immunoblotting Analyses Reveal that the Abundance of Actin, Tubulin, Synaptophysin and EEA1 Proteins is Altered in the Brains of Aged Mice. / 21.08.2020 / PubMed / Full text
• Exercise Attenuates Brain Aging by Rescuing Down-Regulated Wnt/β-Catenin Signaling in Aged Rats. / 2020 / PubMed / Full text
• Concurrent nicotine exposure to prenatal alcohol consumption alters the hippocampal and cortical neurotoxicity. / 01.2020 / PubMed / Full text

FAP

• Rapamycin Extends Life Span in Apc Colon Cancer FAP Model. / 15.09.2020 / PubMed / Full text
• Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors. / 14.02.2020 / PubMed / Full text
• Control of Muscle Fibro-Adipogenic Progenitors by Myogenic Lineage is Altered in Aging and Duchenne Muscular Dystrophy. / 2019 / PubMed / Full text

IRS1

• MicroRNA-34a causes ceramide accumulation and effects insulin signaling pathway by targeting ceramide kinase (CERK) in aging skeletal muscle. / 06.2020 / PubMed / Full text
• Longevity in response to lowered insulin signaling requires glycine N-methyltransferase-dependent spermidine production. / 01.2020 / PubMed / Full text
• Serine Phosphorylation of IRS1 Correlates with Aβ-Unrelated Memory Deficits and Elevation in Aβ Level Prior to the Onset of Memory Decline in AD. / 17.08.2019 / PubMed / Full text

SMS

• Does a Live Performance Impact Synchronization to Musical Rhythm in Cognitively Impaired Elderly? / 2020 / PubMed / Full text
• Testing the effectiveness of physical activity advice delivered via text messaging vs. human phone advisors in a Latino population: The On The Move randomized controlled trial design and methods. / 08.2020 / PubMed / Full text

GPX4

• l-carnitine supplementation during in vitro culture regulates oxidative stress in embryos from bovine aged oocytes. / 02.2020 / PubMed / Full text
• Dietary Selenium Supplementation Ameliorates Female Reproductive Efficiency in Aging Mice. / 11.12.2019 / PubMed / Full text

IGFBP3

• Cellular and Molecular Biomarkers Indicate Premature Aging in Pseudoxanthoma Elasticum Patients. / 05.2020 / PubMed / Full text
• Paracrine senescence of human endometrial mesenchymal stem cells: a role for the insulin-like growth factor binding protein 3. / 17.01.2020 / PubMed / Full text

IQGAP1

• IQGAP1-dysfunction leads to induction of senescence in human vascular smooth muscle cells. / 09.2020 / PubMed / Full text
• Hyaluronan-binding protein 1 (HABP1) overexpression triggers induction of senescence in fibroblasts cells. / 06.2020 / PubMed / Full text

TLR1

• Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. / 01.12.2020 / PubMed / Full text
• Association of TLR gene variants in a Czech Red Pied cattle population with reproductive traits. / 02.2020 / PubMed / Full text

MPI

• Age-related decline of lymphatic drainage from the eye: A noninvasive in vivo photoacoustic tomography study. / 05.2020 / PubMed / Full text
• Interest of the multidimensional prognostic index (MPI) as an assessment tool in hospitalized patients in geriatrics. / 01.12.2019 / PubMed / Full text

EPO

• Regulation of muscle and metabolic physiology by hypothalamic erythropoietin independently of its peripheral action. / 02.2020 / PubMed / Full text
• Red Blood Cell Lifespan Shortening in Patients with Early-Stage Chronic Kidney Disease. / 2019 / PubMed / Full text

CXCR2

• CXCL5-CXCR2 signaling is a senescence-associated secretory phenotype in preimplantation embryos. / 10.2020 / PubMed / Full text
• Senescence in Wound Repair: Emerging Strategies to Target Chronic Healing Wounds. / 2020 / PubMed / Full text

TLR2

• Changes in salivary microbial sensing proteins CD14 and TLR2 with aging. / 07.2020 / PubMed / Full text
• Culture Model for Non-human Primate Choroid Plexus. / 2019 / PubMed / Full text

AHR

• Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging. / 01.09.2020 / PubMed / Full text
• Role of the Aryl Hydrocarbon Receptor in Environmentally Induced Skin Aging and Skin Carcinogenesis. / 28.11.2019 / PubMed / Full text

C6

• Evolution of the Aroma of Treixadura Wines during Bottle Aging. / 08.10.2020 / PubMed / Full text
• D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway. / 29.09.2020 / PubMed / Full text

HMGA2

• 4D Genome Rewiring during Oncogene-Induced and Replicative Senescence. / 07.05.2020 / PubMed / Full text
• The protective effects of HMGA2 in the senescence process of bone marrow-derived mesenchymal stromal cells. / 04.2020 / PubMed / Full text

BACE1

• Electric Stimulation of Neurogenesis Improves Behavioral Recovery After Focal Ischemia in Aged Rats. / 2020 / PubMed / Full text
• Disruption of synaptic expression pattern and age-related DNA oxidation in a neuronal model of lead-induced toxicity. / 05.2020 / PubMed / Full text

C2

• [Effects of resistance training on mitochondrial function in skeletal muscle of aging rats]. / 03.2020 / PubMed / Full text
• Structural and functional characterization of Solanum lycopersicum phosphatidylinositol 3-kinase C2 domain. / 03.2020 / PubMed / Full text

CYP2C19

• Physiologically Based Pharmacokinetic Approach Can Successfully Predict Pharmacokinetics of Citalopram in Different Patient Populations. / 04.2020 / PubMed / Full text
• Longitudinal exposure of English primary care patients to pharmacogenomic drugs: An analysis to inform design of pre-emptive pharmacogenomic testing. / 12.2019 / PubMed / Full text

SDC1

• Olmesartan alleviates bleomycin-mediated vascular smooth muscle cell senescence via the miR-665/SDC1 axis. / 2020 / PubMed / Full text
• Sulfated syndecan 1 is critical to preventing cellular senescence by modulating fibroblast growth factor receptor endocytosis. / 08.2020 / PubMed / Full text

C5

• The C5-75 Program: Meeting the Need for Efficient, Pragmatic Frailty Screening and Management in Primary Care. / 23.06.2020 / PubMed / Full text
• Can a relatively large spinal cord for the dural sac influence severity of paralysis in elderly patients with cervical spinal cord injury caused by minor trauma? / 26.06.2020 / PubMed / Full text

MME

• Geriatric Opioid Harm Reduction: Interprofessional Student Learning Outcomes. / 01-12.2020 / PubMed / Full text
• Effectiveness of local anesthetic injection in geriatric patients following operative management of proximal and diaphyseal femur fracture. / 11.2019 / PubMed / Full text

DRD2

• Cortical thickness mediates the relationship between DRD2 C957T polymorphism and executive function across the adult lifespan. / 11.11.2020 / PubMed / Full text
• The relationship of age and DRD2 polymorphisms to frontostriatal brain activity and working memory performance. / 12.2019 / PubMed / Full text

LPL

• Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects. / 09.2020 / PubMed / Full text
• Influence of common health disorders on the length of productive life and stayability in German Holstein cows. / 01.2020 / PubMed / Full text

ELOVL2

• ELOVL2: Not just a biomarker of aging. / 2020 / PubMed / Full text
• The lipid elongation enzyme ELOVL2 is a molecular regulator of aging in the retina. / 02.2020 / PubMed / Full text

CSF1R

• CSF1R inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice. / 02.02.2020 / PubMed / Full text
• Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units. / 05.11.2019 / PubMed / Full text

PML

• Progressive multifocal leukoencephalopathy in dimethyl fumarate-treated multiple sclerosis patients. / 18.08.2020 / PubMed / Full text
• PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson-Gilford progeria syndrome. / 06.2020 / PubMed / Full text

FSHR

• FSHR ablation induces depression-like behaviors. / 08.2020 / PubMed / Full text
• Direct actions of gonadotropins beyond the reproductive system and their role in human aging and neoplasia [Bezpośrednie działanie gonadotropin poza układem rozrodczym i ich rola w starzeniu się i nowotworzeniu u człowieka]. / 2019 / PubMed / Full text

E2F1

• Regulation of E2F1 activity via PKA-mediated phosphorylations. / 2020 / PubMed / Full text
• Astragaloside IV ameliorates radiation-induced senescence via antioxidative mechanism. / 08.2020 / PubMed / Full text

MBP

• Demyelination associated with chronic arsenic exposure in Wistar rats. / 15.04.2020 / PubMed / Full text
• Natural killer cells as participants in pathogenesis of rat experimental autoimmune encephalomyelitis (EAE): lessons from research on rats with distinct age and strain. / 2019 / PubMed / Full text

ABCG2

• Contribution of senescence in human endometrial stromal cells during proliferative phase to embryo receptivity†. / 23.06.2020 / PubMed / Full text
• ABCG2 rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population. / 17.03.2020 / PubMed / Full text

SPARC

• SPARC Metrics Provide Mobility Smoothness Assessment in Oldest-Old With and Without a History of Falls: A Case Control Study. / 2020 / PubMed / Full text
• Reduced fibrillar collagen accumulation in skeletal muscle of secreted protein acidic and rich in cysteine (SPARC)-null mice. / 29.11.2019 / PubMed / Full text

LTA

• Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice. / 02.2020 / PubMed / Full text
• The change of pain classes over time: a latent transition analysis. / 02.2020 / PubMed / Full text

ERG

• Effect of age and sex on neurodevelopment and neurodegeneration in the healthy eye: Longitudinal functional and structural study in the Long-Evans rat. / 11.2020 / PubMed / Full text
• Mice With a Combined Deficiency of Superoxide Dismutase 1 (Sod1), DJ-1 (Park7), and Parkin (Prkn) Develop Spontaneous Retinal Degeneration With Aging. / 03.09.2019 / PubMed / Full text

NPR1

• The NPR1-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana. / 03.12.2020 / PubMed / Full text
• Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis. / 07.2020 / PubMed / Full text

LEP

• Age- and Sex-Specific Changes in Lower-Limb Muscle Power Throughout the Lifespan. / 18.06.2020 / PubMed / Full text
• The Copenhagen Sarcopenia Study: lean mass, strength, power, and physical function in a Danish cohort aged 20-93 years. / 12.2019 / PubMed / Full text

POT1

• MiR-185 targets POT1 to induce telomere dysfunction and cellular senescence. / 18.07.2020 / PubMed / Full text
• Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence. / 2019 / PubMed / Full text

FGA

• Goal Pursuit, Goal Adjustment, and Pain in Middle-Aged Adults Aging With Physical Disability. / 12.2019 / PubMed / Full text
• Tenacious Goal Pursuit, Flexible Goal Adjustment, and Life Satisfaction Among Chinese Older Adult Couples. / 01.2020 / PubMed / Full text

SYK

• miR-25-3p promotes endothelial cell angiogenesis in aging mice via TULA-2/SYK/VEGFR-2 downregulation. / 17.11.2020 / PubMed / Full text
• Identification of SYK inhibitor, R406 as a novel senolytic agent. / 07.05.2020 / PubMed / Full text

NNT

• Yoga, Health-Related Quality of Life and Mental Well-Being: A Re-analysis of a Meta-analysis Using the Quality Effects Model. / 16.09.2020 / PubMed / Full text
• Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database. / 02.2020 / PubMed / Full text

VDAC1

• Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian longevity. / 07.2020 / PubMed / Full text
• Changes in the expression of oxidative phosphorylation complexes in the aging intestinal mucosa. / 01.07.2020 / PubMed / Full text

LSS

• Surgical results in older patients with lumbar spinal stenosis according to gait speed in relation to the diagnosis for sarcopenia. / 01-04.2020 / PubMed / Full text
• Streamlining an existing hip fracture patient pathway in an acute tertiary adult Irish hospital to improve patient experience and outcomes. / 22.12.2019 / PubMed / Full text

OGT

• ELT-2 promotes O-GlcNAc transferase OGT-1 expression to modulate Caenorhabditis elegans lifespan. / 06.07.2020 / PubMed / Full text
• Neuronal O-GlcNAcylation Improves Cognitive Function in the Aged Mouse Brain. / 21.10.2019 / PubMed / Full text

VIP

• Alterations in Intrinsic and Synaptic Properties of Hippocampal CA1 VIP Interneurons During Aging. / 2020 / PubMed / Full text
• Nutrition and exercise interventions could ameliorate age-related cognitive decline: a meta-analysis of randomized controlled trials. / 14.10.2020 / PubMed / Full text

CX3CR1

• Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism. / 04.2020 / PubMed / Full text
• Muscle Injury Induces Postoperative Cognitive Dysfunction. / 17.02.2020 / PubMed / Full text

CDA

• Cumulative Dis/Advantage and Health Pattern in Late Life: A Comparison between Genders and Welfare State Regimes. / 2019 / PubMed / Full text
• Does numerical similarity alter age-related distractibility in working memory? / 2019 / PubMed / Full text

DCX

• GSK-3β activation accelerates early-stage consumption of Hippocampal Neurogenesis in senescent mice. / 2020 / PubMed / Full text
• Doublecortin and IGF-1R protein levels are reduced in spite of unchanged DNA methylation in the hippocampus of aged rats. / 04.2020 / PubMed / Full text

MCU

• A rare case of Epstein-Barr virus-positive mucocutaneous ulcer that developed into an intestinal obstruction: a case report. / 13.01.2020 / PubMed / Full text
• Inhibition of Mitochondrial Calcium Overload by SIRT3 Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue. / 02.2020 / PubMed / Full text

BAX

• Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-X -BAX interaction. / 10.2020 / PubMed / Full text
• CREB Signaling Mediates Dose-Dependent Radiation Response in the Murine Hippocampus Two Years after Total Body Exposure. / 03.01.2020 / PubMed / Full text

HMGCR

• Cholesterol Homeostasis: An In Silico Investigation into How Aging Disrupts Its Key Hepatic Regulatory Mechanisms. / 30.09.2020 / PubMed / Full text
• Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence. / 01.2020 / PubMed / Full text

CBS

• Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity. / 02.08.2020 / PubMed / Full text
• Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase. / 06.2020 / PubMed / Full text

CDK4

• Emerging Roles for the [i]INK4a/ARF[/i] ([i]CDKN2A[/i]) Locus in Adipose Tissue: Implications for Obesity and Type 2 Diabetes. / 22.09.2020 / PubMed / Full text
• Guilu Erxian Glue () Inhibits Chemotherapy-Induced Bone Marrow Hematopoietic Stem Cell Senescence in Mice May via p16 -Rb Signaling Pathway. / 11.2020 / PubMed / Full text

BPI

• High TARC plasma levels confer protection to long living individuals by inducing M2 profile. / 01.2021 / PubMed / Full text
• Circulating BPIFB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals. / 2020 / PubMed / Full text

PDK1

• Inhibition of 3-phosphoinositide-dependent protein kinase 1 (PDK1) can revert cellular senescence in human dermal fibroblasts. / 08.12.2020 / PubMed / Full text
• The Impact of the PI3K/Akt Signaling Pathway in Anxiety and Working Memory in Young and Middle-Aged PDK1 K465E Knock-In Mice. / 2020 / PubMed / Full text

CR1

• Single Nucleotide Polymorphisms in Alzheimer's Disease Risk Genes Are Associated with Intrinsic Connectivity in Middle Age. / 2020 / PubMed / Full text
• The whale shark genome reveals how genomic and physiological properties scale with body size. / 25.08.2020 / PubMed / Full text

NPY

• Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells. / 22.05.2020 / PubMed / Full text
• Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice. / 03.2020 / PubMed / Full text

HRAS

• How do combinations of unhealthy behaviors relate to attitudinal factors and subjective health among the adult population in the Netherlands? / 03.04.2020 / PubMed / Full text
• Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype. / 07.02.2020 / PubMed / Full text

GRN

• Stressful development: Integrating endoderm development, stress, and longevity. / 08.12.2020 / PubMed / Full text
• A Scoping Review of the Evidence About the Nurses Improving Care for Healthsystem Elders (NICHE) Program. / 04.11.2019 / PubMed / Full text

TRPV4

• TRPV4 receptor as a functional sensory molecule in bladder urothelium: Stretch-independent, tissue-specific actions and pathological implications. / 01.2020 / PubMed / Full text
• Exercise restores impaired endothelium-derived hyperpolarizing factor-mediated vasodilation in aged rat aortic arteries via the TRPV4-K 2.3 signaling complex. / 2019 / PubMed / Full text

PTH

• Vitamin D Receptor Polymorphisms in Sex-Frailty Paradox. / 05.09.2020 / PubMed / Full text
• Parathyroid hormone ameliorates temporomandibular joint osteoarthritic-like changes related to age. / 04.2020 / PubMed / Full text

KRAS

• Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging. / 09.2020 / PubMed
• Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. / 16.04.2020 / PubMed / Full text

CIT

• Effect of sex on aging-related decline of dopamine transporter in healthy subjects. / 14.10.2020 / PubMed / Full text
• The Relationship Between the Striatal Dopaminergic Neuronal and Cognitive Function With Aging. / 2020 / PubMed / Full text

RIPK1

• Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. / 18.11.2020 / PubMed / Full text
• Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. / 05.2020 / PubMed / Full text

PCSK9

• Lipoprotein removal mechanisms and aging: implications for the cardiovascular health of the elderly. / 04.2020 / PubMed / Full text
• The role of proprotein convertase subtilisin-kexin type 9 (PCSK9) in the vascular aging process - is there a link? / 10.2019 / PubMed / Full text

SPRY1

• Sprouty1 Prevents Cellular Senescence Maintaining Proliferation and Differentiation Capacity of Human Adipose Stem/Progenitor Cells. / 13.11.2020 / PubMed / Full text
• Mechanism of SPRY1 methylation regulating natural aging of skin epidermal cells. / 05.2020 / PubMed / Full text

TSPO

• Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge. / 2019 / PubMed / Full text
• Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study. / 10.11.2019 / PubMed / Full text

KLF4

• Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1α Activation. / 25.06.2020 / PubMed / Full text
• Soluble klotho regulates the function of salivary glands by activating KLF4 pathways. / 02.10.2019 / PubMed / Full text

INS

• Melatonin protects INS-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity. / 03.07.2020 / PubMed / Full text
• Nicotine triggers islet β cell senescence to facilitate the progression of type 2 diabetes. / 08.2020 / PubMed / Full text

SAG

• WRKY42 transcription factor positively regulates leaf senescence through modulating SA and ROS synthesis in Arabidopsis thaliana. / 09.2020 / PubMed / Full text
• Neurogenesis in the inner ear: the zebrafish statoacoustic ganglion provides new neurons from a Neurod/Nestin-positive progenitor pool well into adulthood. / 10.04.2020 / PubMed / Full text

JAK1

• Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling. / 01.05.2020 / PubMed / Full text
• The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Through JAK1. / 2019 / PubMed / Full text

F5

• Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis. / 02.2020 / PubMed / Full text
• Fermentation of Blackberry with [i]L. plantarum[/i] JBMI F5 Enhance the Protection Effect on UVB-Mediated Photoaging in Human Foreskin Fibroblast and Hairless Mice through Regulation of MAPK/NF-κB Signaling. / 11.10.2019 / PubMed / Full text

ACR

• Progenitor cell niche senescence reflects pathology of the parotid salivary gland in primary Sjögren's syndrome. / 01.10.2020 / PubMed / Full text
• Jumping Joints: The Complex Relationship Between Osteoarthritis and Jumping Mechanography. / 02.2020 / PubMed / Full text

TMPRSS2

• Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants. / 09.09.2020 / PubMed / Full text
• Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. / 03.06.2020 / PubMed / Full text

CXCL1

• Contusion spinal cord injury upregulates p53 protein expression in rat soleus muscle at multiple timepoints but not key senescence cytokines. / 02.2020 / PubMed / Full text
• Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy. / 2019 / PubMed / Full text

HP

• A narrative review of highly processed food addiction across the lifespan. / 28.10.2020 / PubMed / Full text
• Beta Human Papillomavirus 8E6 Attenuates LATS Phosphorylation after Failed Cytokinesis. / 01.06.2020 / PubMed / Full text

GATA4

• Epigenetics and Vascular Senescence-Potential New Therapeutic Targets? / 2020 / PubMed / Full text
• Prolonged treatment with Y-27632 promotes the senescence of primary human dermal fibroblasts by increasing the expression of IGFBP-5 and transforming them into a CAF-like phenotype. / 25.08.2020 / PubMed / Full text

ADM

• Assessment of age-related differences in decomposition-based quantitative EMG in the intrinsic hand muscles: A multivariate approach. / 09.2020 / PubMed / Full text
• Evaluation of transcriptional levels of the natriuretic peptides, endothelin-1, adrenomedullin, their receptors and long non-coding RNAs in rat cardiac tissue as cardiovascular biomarkers of aging. / 01.2020 / PubMed / Full text

CCN3

• CCN3 Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta. / 2020 / PubMed / Full text
• CCN3 (NOV) Drives Degradative Changes in Aging Articular Cartilage. / 13.10.2020 / PubMed / Full text

PSEN2

• Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2. / 2020 / PubMed / Full text
• Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition. / 03.2020 / PubMed / Full text

CPT1C

• Carnitine palmitoyltransferase 1C reverses cellular senescence of MRC-5 fibroblasts via regulating lipid accumulation and mitochondrial function. / 02.2021 / PubMed / Full text
• Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence. / 14.04.2020 / PubMed / Full text

CFTR

• Exercise Physiology Across the Lifespan in Cystic Fibrosis. / 2019 / PubMed / Full text
• Reduced expression of the Ion channel CFTR contributes to airspace enlargement as a consequence of aging and in response to cigarette smoke in mice. / 02.09.2019 / PubMed / Full text

HDAC3

• Histone deacetylase-3: Friend and foe of the brain. / 07.2020 / PubMed / Full text
• Loss of HDAC3 contributes to meiotic defects in aged oocytes. / 12.2019 / PubMed / Full text

FNDC5

• Irisin Correlates Positively With BMD in a Cohort of Older Adult Patients and Downregulates the Senescent Marker p21 in Osteoblasts. / 14.10.2020 / PubMed / Full text
• [Investigation of signal molecules in saliva: prospects of application for diagnostics of myocardial infarction and the aging rate of different age people.] / 2019 / PubMed

ABO

• Allelic distribution of [i]ABO[/i] gene in Chinese centenarians. / 09.2020 / PubMed / Full text
• Genetically Determined ABO Blood Group and its Associations With Health and Disease. / 03.2020 / PubMed / Full text

FGFR1

• Alignment of Alzheimer's disease amyloid β-peptide and klotho. / 11-12.2020 / PubMed / Full text
• Satellite cell-specific ablation of Cdon impairs integrin activation, FGF signalling, and muscle regeneration. / 08.2020 / PubMed / Full text

NOTCH1

• [How Does Aging Contribute to Cancer?] / 09.2020 / PubMed
• H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice. / 10.2019 / PubMed / Full text

SRF

• Changes in snail and SRF expression in the kidneys of diabetic rats during ageing. / 01.2020 / PubMed / Full text
• Mechanosensitive transcriptional coactivators MRTF-A and YAP/TAZ regulate nucleus pulposus cell phenotype through cell shape. / 12.2019 / PubMed / Full text

BPIFB4

• New Insights for BPIFB4 in Cardiovascular Therapy. / 28.09.2020 / PubMed / Full text
• LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice. / 28.08.2019 / PubMed / Full text

MALT1

• MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. / 29.04.2020 / PubMed / Full text
• MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging. / 2019 / PubMed / Full text

MFN2

• Thioredoxin protects mitochondrial structure, function and biogenesis in myocardial ischemia-reperfusion via redox-dependent activation of AKT-CREB- PGC1α pathway in aged mice. / 13.10.2020 / PubMed / Full text
• MFN2 contributes to metabolic disorders and inflammation in the aging of rat chondrocytes and osteoarthritis. / 08.2020 / PubMed / Full text

MMP1

• Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts. / 12.2020 / PubMed / Full text
• A novel multifunctional skin care formulation with a unique blend of antipollution, brightening and antiaging active complexes. / 06.2020 / PubMed / Full text

TBC1D5

• TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry. / 09.06.2020 / PubMed / Full text
• Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling. / 02.09.2019 / PubMed / Full text

ADAM10

• NKG2D Ligand Shedding in Response to Stress: Role of ADAM10. / 2020 / PubMed / Full text
• Chronic Mild Stress Modified Epigenetic Mechanisms Leading to Accelerated Senescence and Impaired Cognitive Performance in Mice. / 10.02.2020 / PubMed / Full text

PLK4

• A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence. / 05.2020 / PubMed / Full text
• Differential expression of AURKA/PLK4 in quiescence and senescence of osteosarcoma U2OS cells. / 04.2020 / PubMed / Full text

FAS

• Five-year change in maximum tongue pressure and physical function in community-dwelling elderly adults. / 09.2020 / PubMed / Full text
• Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity. / 03.2020 / PubMed / Full text

GAL

• Overexpression of Pitx1 attenuates the senescence of chondrocytes from osteoarthritis degeneration cartilage-A self-controlled model for studying the etiology and treatment of osteoarthritis. / 02.2020 / PubMed / Full text
• β-Caryophyllene Reduces DNA Oxidation and the Overexpression of Glial Fibrillary Acidic Protein in the Prefrontal Cortex and Hippocampus of d-Galactose-Induced Aged BALB/c Mice. / 05.2020 / PubMed / Full text

GCA

• Familial aggregation of longevity in giant cell arteritis and polymyalgia rheumatica. / 12.2020 / PubMed / Full text
• Interaction between Alcohol Consumption and Apolipoprotein E (ApoE) Genotype with Cognition in Middle-Aged Men. / 14.07.2020 / PubMed / Full text

PTX3

• Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. / 27.01.2020 / PubMed / Full text
• Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study. / 13.07.2020 / PubMed / Full text

MITF

• Thymocid , a Standardized Black Cumin ([i]Nigella sativa[/i]) Seed Extract, Modulates Collagen Cross-Linking, Collagenase and Elastase Activities, and Melanogenesis in Murine B16F10 Melanoma Cells. / 19.07.2020 / PubMed / Full text
• HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth. / 21.05.2020 / PubMed / Full text

KEAP1

• NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands. / 09.2020 / PubMed / Full text
• Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds. / 18.05.2020 / PubMed / Full text

GAA

• Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia. / 27.07.2020 / PubMed / Full text
• Age-Related Changes in Serum Guanidinoacetic Acid in Women. / 30.12.2019 / PubMed / Full text

RHO

• Conditional reprogramming: next generation cell culture. / 08.2020 / PubMed / Full text
• SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells. / 18.05.2020 / PubMed / Full text

MIA

• Age, cohort, and period effects on metamemory beliefs. / 12.2019 / PubMed / Full text
• Memory Age-based Stereotype Threat: Role of Locus of Control and Anxiety. / 01-02.2020 / PubMed / Full text

GHRH

• Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone. / 18.05.2020 / PubMed / Full text
• Transcriptomic and metabolomic profiling of long-lived growth hormone releasing hormone knock-out mice: evidence for altered mitochondrial function and amino acid metabolism. / 23.02.2020 / PubMed / Full text

PIP

• Potentially inappropriate prescriptions according to explicit and implicit criteria in patients with multimorbidity and polypharmacy. MULTIPAP: A cross-sectional study. / 2020 / PubMed / Full text
• Quality of prescribing predicts hospitalisation in octogenarians: life and living in advanced age: a cohort study in New Zealand (LiLACS NZ). / 19.12.2019 / PubMed / Full text

SRC

• Metabolic characteristics of CD8 T cell subsets in young and aged individuals are not predictive of functionality. / 05.06.2020 / PubMed / Full text

HDAC2

• EEF1A1 deacetylation enables transcriptional activation of remyelination. / 09.07.2020 / PubMed / Full text

UCHL1

• Abolishing UCHL1's hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice. / 04.11.2020 / PubMed / Full text

DUSP8

• MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats. / 12.2019 / PubMed / Full text

CTH

• Anterior Cingulate Structure and Perfusion is Associated with Cerebrospinal Fluid Tau among Cognitively Normal Older Adult APOEɛ4 Carriers. / 2020 / PubMed / Full text

OSM

• Age Differences in Sexual Minority Stress and the Importance of Friendship in Later Life. / 04.11.2020 / PubMed / Full text

NUCB2

• Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise Killifish. / 31.12.2019 / PubMed / Full text

HES1

• A Single-Cell Transcriptomic Atlas of Human Skin Aging. / 23.11.2020 / PubMed / Full text

NES

• Mini-review: Aging of the neuroendocrine system: Insights from nonhuman primate models. / 08.06.2020 / PubMed / Full text

DRD1

• Impact of dopamine-related genetic variants on physical activity in old age - a cohort study. / 24.05.2020 / PubMed / Full text

AOX1

• N1-Methylnicotinamide: An Anti-Ovarian Aging Hormetin? / 09.2020 / PubMed / Full text

LRP1

• Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome. / 06.2020 / PubMed / Full text

SAT1

• Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action. / 08.2020 / PubMed / Full text

MAG

• Exploration of life satisfaction of Korean people with sensory impairments across the lifespan. / 10.2020 / PubMed / Full text

BMP2

• Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells. / 2020 / PubMed / Full text

FOXO1

• l-Theanine attenuates liver aging by inhibiting advanced glycation end products in d-galactose-induced rats and reversing an imbalance of oxidative stress and inflammation. / 03.2020 / PubMed / Full text

MLKL

• Remifentanil preconditioning protects against hypoxia-induced senescence and necroptosis in human cardiac myocytes [i]in vitro[/i]. / 25.06.2020 / PubMed / Full text

CISD2

• CISD2 Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells-As a Potential Therapeutic Target for Neurodegenerative Dementia. / 2020 / PubMed / Full text

SND1

• [Downregulation of SND1 Expression Accelerates Cell Senescence of Human Diploid Fibroblasts 2BS via Modulating the SASP]. / 05.2020 / PubMed / Full text

IGF1R

• Comparison of mitochondrial transplantation by using a stamp-type multineedle injector and platelet-rich plasma therapy for hair aging in naturally aging mice. / 10.2020 / PubMed / Full text

MAPKAPK2

• Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. / 03.12.2019 / PubMed / Full text

STC2

• Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2. / 05.12.2019 / PubMed / Full text

EFS

• The aging bladder phenotype is not the direct consequence of bladder aging. / 11.2019 / PubMed / Full text

NMUR1

• [Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules]. / 2019 / PubMed / Full text

OGG1

• Advanced Age Is Associated with Iron Dyshomeostasis and Mitochondrial DNA Damage in Human Skeletal Muscle. / 27.11.2019 / PubMed / Full text

BMI1

• Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG. / 20.10.2020 / PubMed / Full text

IGFBP7

• Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7. / 03.2020 / PubMed / Full text

LAMP1

• Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain. / 24.06.2020 / PubMed / Full text

KLF2

• KLF2 induces the senescence of pancreatic cancer cells by cooperating with FOXO4 to upregulate p21. / 01.03.2020 / PubMed / Full text

COMT

• The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain. / 05.2020 / PubMed / Full text

IP6K1

• The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle. / 2019 / PubMed / Full text

PRNP

• Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS. / 06.2020 / PubMed / Full text

GSC

• [i]mastermind[/i] regulates niche ageing independently of the [i]Notch[/i] pathway in the [i]Drosophila[/i] ovary. / 29.11.2019 / PubMed / Full text

BANF1

• An additional case of Néstor-Guillermo progeria syndrome diagnosed in early childhood. / 10.2020 / PubMed / Full text

EN1

• Electrochemically detecting DNA methylation in the EN1 gene promoter: implications for understanding ageing and disease. / 27.11.2020 / PubMed / Full text

PPID

• Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population. / 03.2020 / PubMed / Full text

ADH5

• Can Serum Nitrosoproteome Predict Longevity of Aged Women? / 27.11.2020 / PubMed / Full text

NMI

• Age-Dependent Control of Shoulder Muscles During a Reach-and-Lift Task. / 10.12.2019 / PubMed / Full text

GCLM

• Silencing Bach1 alters aging-related changes in the expression of Nrf2-regulated genes in primary human bronchial epithelial cells. / 15.09.2019 / PubMed / Full text

WT1

• Age and weight at first mating affects plasma leptin concentration but no effects on reproductive performance of gilts. / 09.2019 / PubMed / Full text

DCC

• X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation. / 21.10.2019 / PubMed / Full text

ALOX12

• Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer. / 15.05.2020 / PubMed / Full text

COL1A1

• Remodeling process in bone of aged rats in response to resistance training. / 01.09.2020 / PubMed / Full text

GNAQ

• GNAQ expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system. / 01.2020 / PubMed / Full text

GPI

• Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain. / 10.07.2020 / PubMed / Full text

SELENOK

• Dietary selenium deficiency and supplementation differentially modulate the expression of two ER-resident selenoproteins (selenoprotein K and selenoprotein M) in the ovaries of aged mice: Preliminary data. / 09.2020 / PubMed / Full text

DCN

• Decorin inhibits the insulin-like growth factor I signaling in bone marrow mesenchymal stem cells of aged humans. / 26.11.2020 / PubMed / Full text

RAG1

• T cell senescence accelerates Angiotensin II-induced target organ damage. / 12.02.2020 / PubMed / Full text

ITGA3

• A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells. / 17.08.2020 / PubMed / Full text

NRM

• Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation. / 12.2019 / PubMed / Full text

PLIN2

• Cardiac overexpression of perilipin 2 induces atrial steatosis, connexin 43 remodeling, and atrial fibrillation in aged mice. / 01.12.2019 / PubMed / Full text

SOX13

• In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text

FOS

• Muscle atrophy-related myotube-derived exosomal microRNA in neuronal dysfunction: Targeting both coding and long noncoding RNAs. / 05.2020 / PubMed / Full text

GRM3

• Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk. / 04.2020 / PubMed / Full text

USP7

• Deubiquitinase USP7 regulates [i]Drosophila[/i] aging through ubiquitination and autophagy. / 20.11.2020 / PubMed / Full text

TAS2R16

• Taste receptor polymorphisms and longevity: a systematic review and meta-analysis. / 10.11.2020 / PubMed / Full text

DDO

• New insights on the influence of free d-aspartate metabolism in the mammalian brain during prenatal and postnatal life. / 10.2020 / PubMed / Full text

B4GALT1

• Expression of β-1,4-galactosyltransferases during Aging in Caenorhabditis elegans. / 2020 / PubMed / Full text

FGFR4

• FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. / 14.10.2020 / PubMed / Full text

ENTPD7

• Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 (ENTPD7). / 23.08.2019 / PubMed / Full text

PTTG1

• [Down-regulated PTTG1 expression promotes the senescence of human prostate cancer LNCaP-AI]. / 03.2019 / PubMed

POLL

• Temporal trends in loss of life expectancy after a cancer diagnosis among the Australian population. / 04.2020 / PubMed / Full text

COL3A1

• Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. / 21.12.2019 / PubMed / Full text

EIF4E

• Transcriptomic evidence that insulin signalling pathway regulates the ageing of subterranean termite castes. / 18.05.2020 / PubMed / Full text

MYSM1

• MYSM1 Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan. / 11.2020 / PubMed / Full text

S100B

• Aging protects rat cortical slices against to oxygen-glucose deprivation induced damage. / 12.2020 / PubMed / Full text

ATP7A

• Adipocyte-specific disruption of ATPase copper transporting α in mice accelerates lipoatrophy. / 12.2019 / PubMed / Full text

FOXP1

• GATA6 regulates aging of human mesenchymal stem/stromal cells. / 30.11.2020 / PubMed / Full text

TPO

• Megakaryocytes promote osteoclastogenesis in aging. / 07.07.2020 / PubMed / Full text

BCR

• The presence of CLL-associated stereotypic B cell receptors in the normal BCR repertoire from healthy individuals increases with age. / 2019 / PubMed / Full text

ELF3

• High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in [i]Arabidopsis[/i]. / 31.07.2020 / PubMed / Full text

ALB

• Effects of Age on Inflammatory Profiles and Nutrition/Energy Metabolism in Domestic Cats. / 2020 / PubMed / Full text

GPC1

• Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing. / 15.10.2019 / PubMed / Full text

MYB

• Transcriptome profiling of postharvest shoots identifies PheNAP2- and PheNAP3-promoted shoot senescence. / 01.12.2019 / PubMed / Full text

PGLS

• 547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates. / 28.11.2019 / PubMed / Full text

CASP3

• Does cartilage ERα overexpression correlate with osteoarthritic chondrosenescence? Indications from [i]Labisia pumila[/i] OA mitigation. / 09.2019 / PubMed

GRID1

• Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. / 03.2020 / PubMed / Full text

SQSTM1

• The selective autophagy receptor SQSTM1/p62 improves lifespan and proteostasis in an evolutionarily conserved manner. / 04.2020 / PubMed / Full text

PROC

• Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation. / 15.04.2020 / PubMed / Full text

C7

• The Vertebral Artery Convergence to the Cervical Spine in Elders. / 30.09.2019 / PubMed / Full text

PRKDC

• DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis. / 29.08.2019 / PubMed / Full text

DLGAP2

• Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. / 01.09.2020 / PubMed / Full text

IGFBP1

• Role of IGFBP1 in the senescence of vascular endothelial cells and severity of aging‑related coronary atherosclerosis. / 11.2019 / PubMed / Full text

ALK

• Catalog of Lung Cancer Gene Mutations Among Chinese Patients. / 2020 / PubMed / Full text

CDC25A

• Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage. / 10.10.2020 / PubMed / Full text

P4HA3

• Age-associated genes in human mammary gland drive human breast cancer progression. / 15.06.2020 / PubMed / Full text

NLRC4

• Hyperglycemia-induced inflamm-aging accelerates gingival senescence via NLRC4 phosphorylation. / 06.12.2019 / PubMed / Full text

GHR

• Tissue-Specific GHR Knockout Mice: An Updated Review. / 2020 / PubMed / Full text

APOC3

• Positional Obstructive Sleep Apnea Syndrome in Elderly Patients. / 10.02.2020 / PubMed / Full text

CCND3

• The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text

MAP4K3

• MAP4K3/GLK in autoimmune disease, cancer and aging. / 22.10.2019 / PubMed / Full text

PNP

• Temporal Discrimination Thresholds and Proprioceptive Performance: Impact of Age and Nerve Conduction. / 2019 / PubMed / Full text

TRIM27

• TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination. / 04.12.2020 / PubMed / Full text

MATN3

• Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis. / 19.01.2020 / PubMed / Full text

TTR

• Cellular secretion and cytotoxicity of transthyretin mutant proteins underlie late-onset amyloidosis and neurodegeneration. / 04.2020 / PubMed / Full text

NOS3

• Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation. / 22.05.2020 / PubMed / Full text

MLH1

• The somatic mutation landscape of the human body. / 24.12.2019 / PubMed / Full text

RAN

• Rapid automatized naming (RAN): effects of aging on a predictor of reading skill. / 17.08.2020 / PubMed / Full text

FGR

• Aurora kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction. / 06.2020 / PubMed / Full text

DYRK1A

• Altered age-linked regulation of plasma DYRK1A in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load. / 2020 / PubMed / Full text

SMAD1

• TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands. / 26.11.2019 / PubMed / Full text

KCTD12

• The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort. / 2020 / PubMed / Full text

FTO

• Decreased expression of m A demethylase FTO in ovarian aging. / 22.11.2020 / PubMed / Full text

CYP26B1

• Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia. / 20.05.2020 / PubMed / Full text

PER2

• NAD Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging. / 04.06.2020 / PubMed / Full text

TPH1

• [i]Lactobacillus plantarum[/i] DR7 improved brain health in aging rats via the serotonin, inflammatory and apoptosis pathways. / 02.12.2020 / PubMed / Full text

MTR

• Amide proton transfer-weighted magnetic resonance imaging of human brain aging at 3 Tesla. / 03.2020 / PubMed / Full text

SDHB

• Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. / 12.02.2020 / PubMed / Full text

DUSP1

• miR-1468-3p Promotes Aging-Related Cardiac Fibrosis. / 05.06.2020 / PubMed / Full text

EVL

• Health Years in Total: A New Health Objective Function for Cost-Effectiveness Analysis. / 01.2020 / PubMed / Full text

ATG5

• Autophagy and heat-shock response impair stress granule assembly during cellular senescence. / 12.2020 / PubMed / Full text

SIRT2

• Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the SIRT2-dependent H4K16 deacetylation pathway. / 24.01.2020 / PubMed / Full text

OGA

• NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase. / 19.11.2019 / PubMed / Full text

PRDX1

• Active vitamin D supplementation alleviates initiation and progression of nonalcoholic fatty liver disease by repressing the p53 pathway. / 15.01.2020 / PubMed / Full text

XBP1

• Age-dependent impairment of adipose-derived stem cells isolated from horses. / 03.01.2020 / PubMed / Full text

CTLA4

• Horticultural Therapy Reduces Biomarkers of Immunosenescence and Inflammaging in Community-Dwelling Older Adults: A Feasibility Pilot Randomized Controlled Trial. / 18.10.2020 / PubMed / Full text

ESPL1

• Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants. / 09.2020 / PubMed / Full text

PGK2

• Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice. / 01.2020 / PubMed / Full text

SESN2

• Copy Number Alterations in Papillary Thyroid Carcinomas: Does Loss of [i]SESN2[/i] Have a Role in Age-related Different Prognoses? / 09-10.2020 / PubMed / Full text

PDE5A

• Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass. / 23.06.2020 / PubMed / Full text

CTSB

• Myocardial cathepsin D is downregulated in sudden cardiac death. / 2020 / PubMed / Full text

FOXN1

• Thymic rejuvenation via FOXN1-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation. / 17.09.2020 / PubMed / Full text

TRIP13

• BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome. / 02.01.2020 / PubMed / Full text

TEF

• Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response. / 10.2020 / PubMed / Full text

RPS19BP1

• Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence. / 10.2020 / PubMed / Full text

BCL6

• Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation. / 01.07.2020 / PubMed / Full text

NSF

• Effects of air pollution on children from a socioecological perspective. / 15.11.2019 / PubMed / Full text

RACK1

• Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging. / 05.11.2019 / PubMed / Full text

WNT1

• Plasma proteomic profile of age, health span, and all-cause mortality in older adults. / 11.2020 / PubMed / Full text

NTHL1

• Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals. / 04.2020 / PubMed / Full text

CDC42

• Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1. / 05.09.2019 / PubMed / Full text

CCL11

• CCL-11 or Eotaxin-1: An Immune Marker for Ageing and Accelerated Ageing in Neuro-Psychiatric Disorders. / 02.09.2020 / PubMed / Full text

KCNQ4

• Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss. / 2020 / PubMed / Full text

CXCL8

• Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. / 2020 / PubMed / Full text

A2M

• Age-Dependent Variation in Glycosylation Features of Alpha-2-Macroglobulin. / 12.2019 / PubMed / Full text

KLF6

• Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence. / 2019 / PubMed / Full text

CPT1A

• Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells. / 03.01.2020 / PubMed / Full text

SNCA

• Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease. / 22.11.2019 / PubMed / Full text

COPE

• Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the COPE-study. / 09.04.2020 / PubMed / Full text

L1CAM

• Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression. / 12.09.2019 / PubMed / Full text

AVP

• Plasma oxytocin and vasopressin levels in young and older men and women: Functional relationships with attachment and cognition. / 12.2019 / PubMed / Full text

NT5E

• The NT5E gene variant strongly affects the degradation rate of inosine 5'-monophosphate under postmortem conditions in Japanese Black beef. / 12.2019 / PubMed / Full text

NDUFS8

• Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity. / 01.10.2020 / PubMed / Full text

CBX3

• Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text

MEOX2

• Reduced expression of microRNA-130a promotes endothelial cell senescence and age-dependent impairment of neovascularization. / 26.05.2020 / PubMed / Full text

INSL3

• Effect of Thyroxine Replacement on Leydig Cell and Sertoli Cell Function in Men with Hypothyroidism. / 05-06.2020 / PubMed / Full text

CLEC3B

• CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging. / 16.09.2020 / PubMed / Full text

CYP1A1

• Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population. / 10.2019 / PubMed / Full text

BHLHE40

• Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1. / 07.2020 / PubMed / Full text

SUCNR1

• [The effect of Mexidol on cerebral mitochondriogenesis at a young age and during aging]. / 2020 / PubMed / Full text

NEO1

• Neogenin-1 distinguishes between myeloid-biased and balanced [i]Hoxb5[/i] mouse long-term hematopoietic stem cells. / 10.12.2019 / PubMed / Full text

TAAR1

• Minimal Age-Related Alterations in Behavioral and Hematological Parameters in Trace Amine-Associated Receptor 1 (TAAR1) Knockout Mice. / 03.2020 / PubMed / Full text

IDE

• Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity. / 2020 / PubMed / Full text

TRAF3

• TRAF3, a Target of MicroRNA-363-3p, Suppresses Senescence and Regulates the Balance Between Osteoblastic and Adipocytic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells. / 01.06.2020 / PubMed / Full text

ROCK2

• Physical exercise increases ROCK activity in the skeletal muscle of middle-aged rats. / 03.2020 / PubMed / Full text

VHL

• Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a VHL-1-independent transcriptional response. / 12.2020 / PubMed / Full text

BRD2

• Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice. / 2020 / PubMed / Full text

SIK3

• Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids. / 25.09.2020 / PubMed / Full text

TLR9

• Age-Associated B Cells. / 26.04.2020 / PubMed / Full text

GZMK

• Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK CD8 T Cells as Conserved Hallmark of Inflammaging. / 21.11.2020 / PubMed / Full text

KDM2A

• SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. / 25.06.2020 / PubMed / Full text

ZC3H12A

• Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation. / 12.2019 / PubMed / Full text

JUNB

• Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of JUNB. / 19.02.2020 / PubMed / Full text

WNT7A

• Exogenous Expression of WNT7A in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents. / 2020 / PubMed / Full text

GCK

• The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing. / 12.2019 / PubMed / Full text

UACA

• Knockdown of [i]UACA[/i] inhibitsproliferation and invasion and promotes senescence of hepatocellular carcinoma cells. / 2018 / PubMed / Full text

SFPQ

• Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis. / 08.04.2020 / PubMed / Full text

PEX5

• Aging lowers PEX5 levels in cortical neurons in male and female mouse brains. / 09.2020 / PubMed / Full text

TTL

• Longitudinal Associations of Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio with Biomarkers of Oxidative Stress in Older Adults: Results of a Large Cohort Study. / 2020 / PubMed / Full text

SCN2B

• MicroRNA‑449a regulates the progression of brain aging by targeting SCN2B in SAMP8 mice. / 04.2020 / PubMed / Full text

CCL20

• p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. / 06.2020 / PubMed / Full text

RAF1

• Circular [i]ANRIL[/i] isoforms switch from repressors to activators of [i]p15/CDKN2B[/i] expression during RAF1 oncogene-induced senescence. / 29.09.2020 / PubMed / Full text

DPYSL2

• Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text

PEX19

• A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells. / 02.2020 / PubMed / Full text

SPRTN

• Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging. / 03.09.2020 / PubMed / Full text

MPHOSPH6

• Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text

NRL

• Development of a cyclophosphamide stress test to predict resilience to aging in mice. / 12.2020 / PubMed / Full text

SCO1

• Real-Time PCR Analysis of Metabolism-Related Genes in a Long-Lived Model of C. elegans. / 2020 / PubMed / Full text

MYCN

• Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells. / 2020 / PubMed / Full text

CPNE1

• Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence. / 04.12.2020 / PubMed / Full text

PLN

• An analysis of the costs of treating aged patients in a large clinical hospital in Poland under the pressure of recent demographic trends. / 2020 / PubMed / Full text

REV1

• REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. / 17.11.2020 / PubMed / Full text

CRBN

• Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity. / 24.04.2020 / PubMed / Full text

SCN2A

• Na 1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age. / 09.09.2019 / PubMed / Full text

CHI3L1

• Postsynaptic damage and microglial activation in AD patients could be linked CXCR4/CXCL12 expression levels. / 15.12.2020 / PubMed / Full text

GREM2

• Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis. / 12.2019 / PubMed / Full text

SATB1

• Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons. / 03.10.2019 / PubMed / Full text

FOXA1

• Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer. / 28.09.2019 / PubMed / Full text

IDH2

• Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions. / 10.09.2019 / PubMed / Full text

GIP

• Absence of GIP secretion alleviates age-related obesity and insulin resistance. / 04.2020 / PubMed / Full text

CCL17

• Aging and chronic high-fat feeding negatively affects kidney size, function, and gene expression in CTRP1-deficient mice. / 21.10.2020 / PubMed / Full text

LHCGR

• Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats. / 11.10.2020 / PubMed / Full text

MTHFR

• One-carbon metabolism supplementation improves outcome after stroke in aged male MTHFR-deficient mice. / 12.2019 / PubMed / Full text

GBA

• Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease. / 08.11.2019 / PubMed / Full text

DPP6

• A novel structure associated with aging is augmented in the DPP6-KO mouse brain. / 23.11.2020 / PubMed / Full text

SSB

• Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study. / 03.12.2019 / PubMed / Full text

GUK1

• Characterization of the impact of GMP/GDP synthesis inhibition on replicative lifespan extension in yeast. / 08.2020 / PubMed / Full text

SLC16A7

• Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach. / 23.10.2020 / PubMed / Full text

HGD

• High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans. / 2019 / PubMed / Full text

MFSD2A

• Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease. / 20.12.2019 / PubMed / Full text

CDKN2A

• Association between Nrf2 and CDKN2A expression in patients with end-stage renal disease: a pilot study. / 13.07.2020 / PubMed / Full text

ACD

• Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging. / 02.12.2019 / PubMed / Full text

SMAD2

• Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation. / 02.2020 / PubMed / Full text

LRP4

• Multiple MuSK signaling pathways and the aging neuromuscular junction. / 13.07.2020 / PubMed / Full text

CD63

• Cellular senescence contributes to age-dependent changes in circulating extracellular vesicle cargo and function. / 03.2020 / PubMed / Full text

CCR5

• [Enhancement can do harm]. / 08-09.2019 / PubMed / Full text

CDKN1A

• Involvement of CDKN1A (p21) in cellular senescence in response to heat and irradiation stress during preimplantation development. / 05.2020 / PubMed / Full text

SLC6A4

• The Psilocybin-Telomere Hypothesis: An empirically falsifiable prediction concerning the beneficial neuropsychopharmacological effects of psilocybin on genetic aging. / 01.2020 / PubMed / Full text

KDM2B

• Identification of Structural Elements of the Lysine Specific Demethylase 2B CxxC Domain Associated with Replicative Senescence Bypass in Primary Mouse Cells. / 06.2020 / PubMed / Full text

AP2B1

• Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice. / 20.12.2019 / PubMed / Full text

UGT2B28

• Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a UGT2B28 genomic variation. / 05.12.2019 / PubMed / Full text

ACVR1

• Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome. / 2019 / PubMed / Full text

RNF13

• The effects of environmental stressors on candidate aging associated genes. / 08.2020 / PubMed / Full text

VSIG4

• Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue. / 10.2020 / PubMed / Full text

CXCL14

• Identification of genes associated with endometrial cell aging. / 01.12.2020 / PubMed / Full text

FAAH

• Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice. / 02.2020 / PubMed / Full text

RNF10

• Reduced RING finger protein 10 expression in macrophages is associated with aging-related inflammation. / 28.11.2020 / PubMed / Full text

NDRG2

• NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain. / 04.01.2020 / PubMed / Full text

BAZ2B

• Two conserved epigenetic regulators prevent healthy ageing. / 03.2020 / PubMed / Full text

LRP6

• Low-density lipoprotein receptor-related protein 6-mediated signaling pathways and associated cardiovascular diseases: diagnostic and therapeutic opportunities. / 04.2020 / PubMed / Full text

POU5F1

• Cell quality evaluation with gene expression analysis of spheroids (3D) and adherent (2D) adipose stem cells. / 24.10.2020 / PubMed / Full text

HDAC10

• Middle-aged female rats lack changes in histone H3 acetylation in the anterior hypothalamus observed in young females on the day of a luteinizing hormone surge. / 17.09.2019 / PubMed / Full text

BOC

• Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations. / 01.05.2020 / PubMed / Full text

APPL1

• Insulin and adipokine signaling and their cross-regulation in postmortem human brain. / 12.2019 / PubMed / Full text

HDAC1

• HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease. / 18.05.2020 / PubMed / Full text

CDH1

• Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation. / 15.09.2020 / PubMed / Full text

ATG3

• Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells. / 01.04.2020 / PubMed / Full text

AREG

• Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. / 12.2019 / PubMed / Full text

IGFBP4

• Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey. / 11.10.2019 / PubMed / Full text

FGF2

• The influence of fibroblast growth factor 2 on the senescence of human adipose-derived mesenchymal stem cells during long-term culture. / 04.2020 / PubMed / Full text

PTPN11

• Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array. / 01.10.2020 / PubMed / Full text

NPM1

• Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats. / 29.11.2019 / PubMed / Full text

NOP10

• Pseudouridylation defect due to [i]DKC1[/i] and [i]NOP10[/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. / 30.06.2020 / PubMed / Full text

FADS1

• Aging and FADS1 polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U- C]linoleic acid. / 09.2019 / PubMed / Full text

PBX1

• Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence. / 10.2020 / PubMed / Full text

RXFP3

• The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage. / 03.12.2019 / PubMed / Full text

IDS

• Effect of immediate dentine sealing on the aging and fracture strength of lithium disilicate inlays and overlays. / 10.2020 / PubMed / Full text

HTT

• Biological Aging and the Cellular Pathogenesis of Huntington's Disease. / 2020 / PubMed / Full text

PRDX3

• Proteomic analyses reveal that ginsenoside Rg3([i]S[/i]) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin. / 01.2020 / PubMed / Full text

FOXO4

• FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. / 20.01.2020 / PubMed / Full text

ICE1

• ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1. / 19.02.2020 / PubMed / Full text

CTCF

• New targeted approaches for epigenetic age predictions. / 24.06.2020 / PubMed / Full text

CPT2

• The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats. / 09.2020 / PubMed / Full text

VCAM1

• Sunitinib facilitates metastatic breast cancer spreading by inducing endothelial cell senescence. / 29.09.2020 / PubMed / Full text

HDC

• Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells. / 07.05.2020 / PubMed / Full text

AGER

• Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model. / 01.10.2019 / PubMed / Full text

CCL28

• Age-related chemokine alterations affect IgA secretion and gut immunity in female mice. / 10.2020 / PubMed / Full text

WNT10A

• Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development. / 01.04.2020 / PubMed / Full text

DDC

• N-Acetyl Cysteine Attenuates the Sarcopenia and Muscle Apoptosis Induced by Chronic Liver Disease. / 2019 / PubMed / Full text

SIRT5

• Lysine malonylation and propionylation are prevalent in human lens proteins. / 01.2020 / PubMed / Full text

CCR3

• Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro. / 04.02.2020 / PubMed / Full text

FYN

• An inhibitor role of Nrf2 in the regulation of myocardial senescence and dysfunction after myocardial infarction. / 15.10.2020 / PubMed / Full text

RICTOR

• Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. / 11.2019 / PubMed / Full text

AQP3

• Transbuccal platform for delivery of lipogenic actives to facial skin: Because fat matters. / 08.2020 / PubMed / Full text

ASXL1

• ASXL1 mutation in clonal hematopoiesis. / 03.2020 / PubMed / Full text

SUV39H1

• Increase in hippocampal histone H3K9me3 is negatively correlated with memory in old male mice. / 04.2020 / PubMed / Full text

CDC20

• Premature aging syndrome showing random chromosome number instabilities with CDC20 mutation. / 11.2020 / PubMed / Full text

DOCK11

• [Immunosenescence: The Forefront of Infection and Trophic Control]. / 2020 / PubMed / Full text

PNN

• Hyaluronan degradation and release of a hyaluronan-aggrecan complex from perineuronal nets in the aged mouse brain. / 28.11.2020 / PubMed / Full text

KIN

• The noncanonical small heat shock protein HSP-17 from [i]Caenorhabditis elegans[/i] is a selective protein aggregase. / 06.03.2020 / PubMed / Full text

NMS

• Uncontrolled Diabetes as an Associated Factor with Dynapenia in Adults Aged 50 Years or Older: Sex Differences. / 22.05.2020 / PubMed / Full text

CD80

• The aging common marmoset's immune system: From junior to senior. / 06.2020 / PubMed / Full text

MCM9

• MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors. / 10.09.2019 / PubMed / Full text

XDH

• Enhancing xanthine dehydrogenase activity is an effective way to delay leaf senescence and increase rice yield. / 11.03.2020 / PubMed / Full text

DNMT1

• DNA Methyltransferase 1 (DNMT1) Function Is Implicated in the Age-Related Loss of Cortical Interneurons. / 2020 / PubMed / Full text

IHH

• Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway. / 01.04.2020 / PubMed / Full text

VGLL4

• The lncRNA MEG3/miR-16-5p/VGLL4 regulatory axis is involved in etoposide-induced senescence of tumor cells. / 03.11.2020 / PubMed / Full text

PDE2A

• TAK-915, a phosphodiesterase 2A inhibitor, ameliorates the cognitive impairment associated with aging in rodent models. / 30.12.2019 / PubMed / Full text

IGFBP2

• Intracellular Insulin-like growth factor binding protein 2 (IGFBP2) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21. / 17.04.2020 / PubMed / Full text

EDARADD

• Age prediction in living: Forensic epigenetic age estimation based on blood samples. / 11.2020 / PubMed / Full text

GSTM2

• Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage. / 07.07.2020 / PubMed / Full text

KCNK2

• Brain age prediction using deep learning uncovers associated sequence variants. / 27.11.2019 / PubMed / Full text

OTC

• Age and growth of stocked juvenile Shoal Bass in a tailwater: Environmental variation and accuracy of daily age estimates. / 2019 / PubMed / Full text

TCF7L2

• A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder. / 03.2020 / PubMed / Full text

GDNF

• GFR-α1 Expression in Substantia Nigra Increases Bilaterally Following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss Following 6-OHDA Nigrostriatal Lesion. / 16.10.2019 / PubMed / Full text

HS2ST1

• Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

PTP4A3

• Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease. / 05.2020 / PubMed / Full text

RIPK3

• Metformin mediates cardioprotection against aging-induced ischemic necroptosis. / 02.2020 / PubMed / Full text

GRIK2

• Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2. / 11-12.2020 / PubMed / Full text

TTN

• LncRNA TTN-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis. / 10.10.2019 / PubMed / Full text

CACNA1S

• Increased calcium channel in the lamina propria of aging rat. / 31.10.2019 / PubMed / Full text

CD19

• Sequential treatment with aT19 cells generates memory CAR-T cells and prolongs the lifespan of Raji-B-NDG mice. / 28.01.2020 / PubMed / Full text

CCL19

• Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention. / 16.09.2019 / PubMed / Full text

PIEZO1

• Niche stiffness underlies the ageing of central nervous system progenitor cells. / 09.2019 / PubMed / Full text

LAG3

• T Cell Transcriptional Profiling and Immunophenotyping Uncover LAG3 as a Potential Significant Target of Immune Modulation in Multiple Myeloma. / 01.2020 / PubMed / Full text

SYNE1

• Nesprin-1 impact on tumorigenic cell phenotypes. / 02.2020 / PubMed / Full text

KIT

• Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-KIT. / 04.2020 / PubMed / Full text

SRM

• [Geriatric specificities of localized renal cell carcinoma]. / 11.2019 / PubMed / Full text

BGN

• Alterations of local functional connectivity in lifespan: A resting-state fMRI study. / 07.2020 / PubMed / Full text

CCND1

• Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells. / 09.2020 / PubMed / Full text

PAX8

• Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging. / 13.09.2019 / PubMed / Full text

PER1

• Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells. / 02.2020 / PubMed / Full text

NOTCH4

• Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH. / 11.2020 / PubMed / Full text

JUN

• Age-Onset Phosphorylation of a Minor Actin Variant Promotes Intestinal Barrier Dysfunction. / 02.12.2019 / PubMed / Full text

IFI27

• Ultraviolet B irradiation-induced keratinocyte senescence and impaired development of 3D epidermal reconstruct. / 01.06.2021 / PubMed / Full text

GSTM1

• The effects of everyday-life exposure to polycyclic aromatic hydrocarbons on biological age indicators. / 03.12.2020 / PubMed / Full text

GPX3

• Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract. / 2019 / PubMed / Full text

IRS2

• Effects of Heshouwuyin on gene expression of the insulin/IGF signalling pathway in rat testis and spermatogenic cells. / 12.2020 / PubMed / Full text

SERPINE1

• Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes. / 15.01.2020 / PubMed / Full text

LPO

• [Features of the changes in lipid peroxidation and activity of Na+/K+-ATPase in the brain of the aged rats in the conditions of two-vessel cerebral ischemia/reperfusion.] / 2019 / PubMed

CX3CL1

• Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice. / 14.05.2020 / PubMed / Full text

TBK1

• Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of TBK1 to facilitate mitophagy. / 01.01.2021 / PubMed / Full text

TPP1

• FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping. / 03.11.2020 / PubMed / Full text

BATF

• LncRNA-ES3 inhibition by Bhlhe40 is involved in high glucose-induced calcification/senescence of vascular smooth muscle cells. / 08.2020 / PubMed / Full text

AMT

• A multi-method comparison of autobiographical memory impairments amongst younger and older adults. / 12.03.2020 / PubMed / Full text

TAZ

• Transcriptional Coactivator TAZ Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence. / 09.01.2020 / PubMed / Full text

CDK1

• MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging. / 02.2020 / PubMed / Full text

KDM3A

• KDM3A and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization. / 22.11.2019 / PubMed / Full text

HCN1

• Protein expression changes of HCN1 and HCN2 in hippocampal subregions of gerbils during the normal aging process. / 11.2019 / PubMed / Full text

TRPC6

• Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype. / 11.2020 / PubMed / Full text

ALKBH8

• Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming . / 01.2020 / PubMed / Full text

ANK3

• Age-related atrophy of cortical thickness and genetic effect of ANK3 gene in first episode MDD patients. / 26.08.2020 / PubMed / Full text

SHH

• Recent advances in SHH medulloblastoma progression: tumor suppressor mechanisms and the tumor microenvironment. / 2019 / PubMed / Full text

MAPK1

• Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1. / 2020 / PubMed / Full text

BAK1

• Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon. / 23.09.2020 / PubMed / Full text

MRE11

• Chromosomal alterations among age-related haematopoietic clones in Japan. / 08.2020 / PubMed / Full text

FOSL2

• LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis. / 03.04.2020 / PubMed / Full text

HSPA1L

• Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L-mitophagy pathway. / 03.2020 / PubMed / Full text

RHEB

• The Rheb-TORC1 signaling axis functions as a developmental checkpoint. / 02.03.2020 / PubMed / Full text

GK

• Progression of diabetic kidney disease in T2DN rats. / 01.12.2019 / PubMed / Full text

U2AF1

• Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs. / 05.03.2020 / PubMed / Full text

ZMPSTE24

• Bone marrow-derived mesenchymal stem cells in three-dimensional co-culture attenuate degeneration of nucleus pulposus cells. / 30.10.2019 / PubMed / Full text

TOMM20

• Effect of aging on mitochondria and metabolism of bovine granulosa cells. / 13.09.2020 / PubMed / Full text

S1PR1

• Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair. / 22.06.2020 / PubMed / Full text

BMP7

• Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting BMP7. / 11.12.2019 / PubMed / Full text

CXCL11

• Endothelial cells under therapy-induced senescence secrete CXCL11, which increases aggressiveness of breast cancer cells. / 10.10.2020 / PubMed / Full text

ADAM17

• ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19. / 2020 / PubMed / Full text

WWP1

• The ubiquitin ligase WWP1 contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart. / 01.10.2020 / PubMed / Full text

HDAC4

• The posttranslational modification of HDAC4 in cell biology: Mechanisms and potential targets. / 02.2020 / PubMed / Full text

DLX5

• Inhibition of microRNA-27b-3p relieves osteoarthritis pain via regulation of KDM4B-dependent DLX5. / 09.2020 / PubMed / Full text

WFDC2

• Differences in biomarkers and molecular pathways according to age for patients with HFrEF. / 01.10.2020 / PubMed / Full text

ASB7

• ASB7 Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation. / 2020 / PubMed / Full text

CDKN2B

• Molecular Genetics and Functional Analysis Implicate [i]CDKN2BAS1-CDKN2B[/i] Involvement in POAG Pathogenesis. / 21.08.2020 / PubMed / Full text

EHF

• Extended high frequency hearing and speech perception implications in adults and children. / 11.2020 / PubMed / Full text

SLC26A2

• Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis. / 01.2020 / PubMed / Full text

MMP13

• Aging aggravates intervertebral disc degeneration by regulating transcription factors toward chondrogenesis. / 02.2020 / PubMed / Full text

ENO1

• Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells. / 2020 / PubMed / Full text

NFKB1

• NFKB1 gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation. / 03.2020 / PubMed / Full text

DNMT3L

• Transient DNMT3L Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast. / 2020 / PubMed / Full text

TFPI

• Identification of cardiovascular health gene variants related to longevity in a Chinese population. / 07.09.2020 / PubMed / Full text

C9orf72

• Carriership of two copies of C9orf72 hexanucleotide repeat intermediate-length alleles is a risk factor for ALS in the Finnish population. / 09.11.2020 / PubMed / Full text

MIB1

• Immunohistochemical detection of senescence markers in human sarcomas. / 02.2020 / PubMed / Full text

F7

• The Pattern of Mu Rhythm Modulation During Emotional Destination Memory: Comparison Between Mild Cognitive Impairment Patients and Healthy Controls. / 2019 / PubMed / Full text

GPX1

• Glutathione peroxidase-1 overexpression reduces oxidative stress, and improves pathology and proteome remodeling in the kidneys of old mice. / 06.2020 / PubMed / Full text

CTSA

• A CTSA-based consultation service to advance research on special and underserved populations. / 16.01.2020 / PubMed / Full text

MYT1

• ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the MYT1-Egln3-Sirt1 Axis. / 01.10.2020 / PubMed / Full text

WASL

• Loss of Wasl improves pancreatic cancer outcome. / 21.05.2020 / PubMed / Full text

PUM1

• Identification of reference genes for RT-qPCR data normalisation in aging studies. / 27.09.2019 / PubMed / Full text

FANCD2

• TFG-maintaining stability of overlooked FANCD2 confers early DNA-damage response. / 24.10.2020 / PubMed / Full text

HFE

• Polyphenol Characterization and Skin-Preserving Properties of Hydroalcoholic Flower Extract from [i]Himantoglossum robertianum[/i] (Orchidaceae). / 14.11.2019 / PubMed / Full text

ITGA5

• Kaempferol alleviates the reduction of developmental competence during aging of porcine oocytes. / 11.2019 / PubMed / Full text

CXCL10

• Age-related decline of interferon-gamma responses in macrophage impairs satellite cell proliferation and regeneration. / 10.2020 / PubMed / Full text

ATF4

• Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78-Loaded Extracellular Vesicles. / 10.12.2020 / PubMed / Full text

CYP2E1

• DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver. / 06.2020 / PubMed / Full text

MYC

• Enhanced proliferative capacity of human preadipocytes achieved by an optimized cultivating method that induces transient activity of hTERT. / 20.08.2020 / PubMed / Full text

TMEM106B

• Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology. / 05.08.2020 / PubMed / Full text

GEM

• The Impact of Geriatric Emergency Management Nurses on the Care of Frail Older Patients in the Emergency Department: a Systematic Review. / 09.2020 / PubMed / Full text

ACLY

• In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase. / 10.2020 / PubMed / Full text

POMC

• Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding. / 14.10.2019 / PubMed / Full text

DNAJB9

• DNAJB9 Inhibits p53-Dependent Oncogene-Induced Senescence and Induces Cell Transformation. / 30.04.2020 / PubMed / Full text

BAD

• I imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway. / 31.10.2020 / PubMed / Full text

TRPC7

• Nociceptive transient receptor potential canonical 7 (TRPC7) mediates aging-associated tumorigenesis induced by ultraviolet B. / 01.2020 / PubMed / Full text

VIM

• Establishment and characterization of a fibroblast cell line from postmortem skin of an adult Chinese muntjac (Muntiacus reevesi). / 02.2020 / PubMed / Full text

DLD

• A preliminary study of cerebral blood flow, aging and dementia in people with Down syndrome. / 12.2020 / PubMed / Full text

PRDX6

• Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task. / 2019 / PubMed / Full text

MED25

• The [i]HAC1[/i] histone acetyltransferase promotes leaf senescence and regulates the expression of [i]ERF022[/i]. / 08.2019 / PubMed / Full text

SELENBP1

• A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity. / 01.2020 / PubMed / Full text

LY6D

• LY6D-induced macropinocytosis as a survival mechanism of senescent cells. / 09.11.2020 / PubMed / Full text

HBP1

• Suppression of p38/HBP1 pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence. / 03-04.2020 / PubMed / Full text

WNT3A

• Chronic WNT/β-catenin signaling induces cellular senescence in lung epithelial cells. / 06.2020 / PubMed / Full text

CARM1

• CARM1 regulates senescence during airway epithelial cell injury in COPD pathogenesis. / 01.11.2019 / PubMed / Full text

RELB

• New control of the senescence barrier in breast cancer. / 2020 / PubMed / Full text

ILDR1

• Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment. / 23.10.2019 / PubMed / Full text

TXNRD2

• Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression. / 10.2020 / PubMed / Full text

STIM1

• Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis. / 02.2020 / PubMed / Full text

MEFV

• The grandfather's fever. / 02.2020 / PubMed / Full text

PSMD14

• Upregulation of deubiquitinase PSMD14 in lung adenocarcinoma (LUAD) and its prognostic significance. / 2020 / PubMed / Full text

HBM

• The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis. / 25.09.2019 / PubMed / Full text

ALOX5

• Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme. / 01.01.2020 / PubMed / Full text

SRL

• Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment. / 04-06.2020 / PubMed / Full text

PSMD11

• The effect and mechanism of 19S proteasome PSMD11/Rpn6 subunit in D-Galactose induced mimetic aging models. / 01.09.2020 / PubMed / Full text

GNE

• Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2 mice. / 10.12.2020 / PubMed / Full text

BMP4

• Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. / 08.09.2020 / PubMed / Full text

NOX4

• Sestrin2 Attenuates Cellular Senescence by Inhibiting NADPH Oxidase 4 Expression. / 24.11.2020 / PubMed / Full text

NKX6-1

• The dynamic methylome of islets in health and disease. / 09.2019 / PubMed / Full text

MAP2

• Protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent. / 11.2020 / PubMed / Full text

SMN2

• Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. / 01.11.2019 / PubMed / Full text

LOX

• 12-LOX catalyzes the oxidation of 2-arachidonoyl-lysolipids in platelets generating eicosanoid-lysolipids that are attenuated by iPLA γ knockout. / 17.04.2020 / PubMed / Full text

GPT

• Brain Structural-Behavioral Correlates Underlying Grooved Pegboard Test Performance Across Lifespan. / 07.07.2020 / PubMed / Full text

IL2

• Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus. / 2020 / PubMed / Full text

ANGPTL2

• Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study. / 01.05.2020 / PubMed / Full text

GAP43

• HDAC inhibition leads to age-dependent opposite regenerative effect upon PTEN deletion in rubrospinal axons after SCI. / 06.2020 / PubMed / Full text

HDAC6

• Inhibition of HDAC6 Attenuates Diabetes-Induced Retinal Redox Imbalance and Microangiopathy. / 09.07.2020 / PubMed / Full text

IL1A

• IL1B triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via CCL2. / 25.10.2020 / PubMed / Full text

NKAP

• NKAP Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors. / 2019 / PubMed / Full text

NACA

• Age and Sex Are Strongly Correlated to the Rate and Type of Mountain Injuries Requiring Search and Rescue Missions. / 12.2019 / PubMed / Full text

ADRA2A

• α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway. / 2020 / PubMed / Full text

HPSE

• Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin. / 07.2020 / PubMed / Full text

BTK

• Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition. / 01.2020 / PubMed / Full text

LGR6

• Effect of defensins-containing eye cream on periocular rhytids and skin quality. / 08.2020 / PubMed / Full text

NLRP12

• Persistent DNA damage-induced NLRP12 improves hematopoietic stem cell function. / 21.05.2020 / PubMed / Full text

GCLC

• Aerobic exercise training partially reverses the impairment of Nrf2 activation in older humans. / 20.11.2020 / PubMed / Full text

DSPP

• Effects of [i]p[/i]-Cresol on Senescence, Survival, Inflammation, and Odontoblast Differentiation in Canine Dental Pulp Stem Cells. / 21.09.2020 / PubMed / Full text

POLR3A

• Nucleolar disruption, activation of P53 and premature senescence in POLR3A-mutated Wiedemann-Rautenstrauch syndrome fibroblasts. / 12.2020 / PubMed / Full text

GABARAP

• Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. / 18.08.2020 / PubMed / Full text

GPR6

• Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy. / 22.09.2020 / PubMed / Full text

CHSY1

• Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in [i]skt[/i] Mice. / 01.2020 / PubMed / Full text

CDK5

• Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence. / 11.2019 / PubMed / Full text

GREM1

• GREM1 inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. / 09.03.2020 / PubMed / Full text

FGF19

• Bile acid receptor agonists in primary biliary cholangitis: Regulation of the cholangiocyte secretome and downstream T cell differentiation. / 05.2019 / PubMed / Full text

GIT2

• Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories. / 12.2019 / PubMed / Full text

SGK1

• Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells. / 05.2020 / PubMed / Full text

SNAP25

• The Biological Foundations of Sarcopenia: Established and Promising Markers. / 2019 / PubMed / Full text

CDK2

• p57 is a master regulator of human adipose derived stem cell quiescence and senescence. / 04.2020 / PubMed / Full text

CRABP2

• Preconception resveratrol intake against infertility: Friend or foe? / 04.2020 / PubMed / Full text

HOXD8

• Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts. / 2020 / PubMed / Full text

ABL1

• European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia. / 04.2020 / PubMed / Full text

AACS

• Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study. / 07.11.2020 / PubMed / Full text

BLM

• [Olmesartan inhibits age-associated migration and invasion of human aortic vascular smooth muscle cells by upregulating miR-3133 axis]. / 30.04.2020 / PubMed / Full text

LOXL2

• Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice. / 27.09.2019 / PubMed / Full text

SENP6

• Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses. / 10.2020 / PubMed / Full text

SRD5A2

• Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II. / 11.2020 / PubMed / Full text

WIPI2

• Neuronal autophagy declines substantially with age and is rescued by overexpression of WIPI2. / 02.2020 / PubMed / Full text

CCL2

• β1 Integrin regulates adult lung alveolar epithelial cell inflammation. / 30.01.2020 / PubMed / Full text

SOX4

• Age-induced accumulation of methylmalonic acid promotes tumour progression. / 09.2020 / PubMed / Full text

SIRT7

• SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer. / 07.2020 / PubMed / Full text

CXCR3

• Senescent hepatocytes enhance natural killer cell activity via the CXCL-10/CXCR3 axis. / 11.2019 / PubMed / Full text

VEGFA

• APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease. / 03.2020 / PubMed / Full text

CXCL13

• RNA-seq data from C-X-C chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype. / 08.2020 / PubMed / Full text

MUC7

• Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model. / 24.09.2019 / PubMed / Full text

CD5

• Comparative proteomic analysis identifies biomarkers for renal aging. / 06.11.2020 / PubMed / Full text

ITGAM

• Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging. / 2019 / PubMed / Full text

ADA

• Adenosine Metabolism in the Cerebral Cortex from Several Mice Models during Aging. / 02.10.2020 / PubMed / Full text

SPR

• Regulation of lifespan by neural excitation and REST. / 10.2019 / PubMed / Full text

RTEL1

• Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants. / 12.2019 / PubMed / Full text

CD33

• Maximum reproductive lifespan correlates with CD33rSIGLEC gene number: Implications for NADPH oxidase-derived reactive oxygen species in aging. / 02.2020 / PubMed / Full text

HMGA1

• Characterization of [i]HMGA1P6[/i] transgenic mouse embryonic fibroblasts. / 09.2020 / PubMed / Full text

FOXM1

• Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression. / 10.11.2020 / PubMed / Full text

SOX9

• Positive Effects of a Young Systemic Environment and High Growth Differentiation Factor 11 Levels on Chondrocyte Proliferation and Cartilage Matrix Synthesis in Old Mice. / 07.2020 / PubMed / Full text

GJC2

• Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging. / 10.2020 / PubMed / Full text

IL15

• Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of IL15. / 27.04.2020 / PubMed / Full text

GDF5

• An embryonic CaVβ1 isoform promotes muscle mass maintenance via GDF5 signaling in adult mouse. / 06.11.2019 / PubMed / Full text

PDCD4

• Petal abscission in roses is associated with the activation of a truncated version of the animal PDCD4 homologue, RbPCD1. / 11.2019 / PubMed / Full text

SMAD3

• Sirtuin 6 deficiency transcriptionally up-regulates TGF-β signaling and induces fibrosis in mice. / 10.01.2020 / PubMed / Full text

WDR5

• Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16 . / 11.2019 / PubMed / Full text

SHD

• Does self-reported hearing difficulty decrease older adults' cognitive and physical functioning? The mediating role of social isolation. / 11.2020 / PubMed / Full text

ECD

• Outcome of Descemet Membrane Endothelial Keratoplasty Using Corneas from Donors ≥80 Years of Age. / 03.2020 / PubMed / Full text

RIF1

• 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. / 02.01.2020 / PubMed / Full text

TAS2R38

• TAS2R38 bitter taste receptor and attainment of exceptional longevity. / 02.12.2019 / PubMed / Full text

ETS1

• The transcription factor ETS1 promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1. / 06.12.2019 / PubMed / Full text

DUT

• Simultaneous liquefaction, saccharification, and fermentation of L-lactic acid using aging paddy rice with hull by an isolated thermotolerant Enterococcus faecalis DUT1805. / 09.2020 / PubMed / Full text

ADORA2B

• Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss. / 12.2020 / PubMed / Full text

POR

• The Ventricular System Enlarges Abnormally in the Seventies, Earlier in Men, and First in the Frontal Horn: A Study Based on More Than 3,000 Scans. / 2019 / PubMed / Full text

DDB1

• DCAF1 regulates Treg senescence via the ROS axis during immunological aging. / 02.11.2020 / PubMed / Full text

DKC1

• Successful liver transplantation in short telomere syndromes without bone marrow failure due to DKC1 mutation. / 05.2020 / PubMed / Full text

GGCT

• Blockade of γ-Glutamylcyclotransferase Enhances Docetaxel Growth Inhibition of Prostate Cancer Cells. / 09.2019 / PubMed / Full text

CHRNA7

• Associations between genetic variations and global motion perception. / 10.2019 / PubMed / Full text

HMGB1

• Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction. / 02.12.2019 / PubMed / Full text

P4HA2

• Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients. / 03.09.2019 / PubMed / Full text

DST

• Ancestral germen/soma distinction in microbes: Expanding the disposable soma theory of aging to all unicellular lineages. / 07.2020 / PubMed / Full text

MGMT

• Cytotoxic and Senolytic Effects of Methadone in Combination with Temozolomide in Glioblastoma Cells. / 23.09.2020 / PubMed / Full text

S100A4

• Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice. / 15.12.2019 / PubMed / Full text

NPW

• Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study. / 09.2020 / PubMed / Full text

RAG2

• Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation. / 2020 / PubMed / Full text

NOS1

• Prepubertal overexposure to manganese induce precocious puberty through GABA receptor/nitric oxide pathway in immature female rats. / 30.01.2020 / PubMed / Full text

RPIA

• Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming. / 20.08.2019 / PubMed / Full text

HLA-DRB1

• The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle. / 11.2020 / PubMed / Full text

LOXL1

• A blackberry-dill extract combination synergistically increases skin elasticity. / 10.2020 / PubMed / Full text

AGT

• SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence. / 06.2020 / PubMed / Full text

ZEB2

• miR-200b regulates cellular senescence and inflammatory responses by targeting ZEB2 in pulmonary emphysema. / 12.2020 / PubMed / Full text

KAT6B

• Aging-associated decrease in the histone acetyltransferase KAT6B is linked to altered hematopoietic stem cell differentiation. / 02.2020 / PubMed / Full text

PDE4D

• Phosphodiesterase PDE4D Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau. / 2020 / PubMed / Full text

CXCL9

• CXCL9 and CXCL10 display an age-dependent profile in Chagas patients: a cohort study of aging in Bambui, Brazil. / 11.05.2020 / PubMed / Full text

SUGCT

• Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype. / 09.2020 / PubMed / Full text

MLN

• Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells. / 2020 / PubMed / Full text

EDF1

• Silencing of FOREVER YOUNG FLOWER Like Genes from Phalaenopsis Orchids Promotes Flower Senescence and Abscission. / 25.11.2020 / PubMed / Full text

CYP7A1

• Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats. / 2019 / PubMed / Full text

MDH1

• Oxidative Damage to the TCA Cycle Enzyme MDH1 Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. / 03.04.2020 / PubMed / Full text

PRDM8

• PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation. / 20.08.2020 / PubMed / Full text

TRIM21

• TRIM21 overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma. / 2020 / PubMed / Full text

IRF8

• IRF8 induces senescence of lung cancer cells to exert its tumor suppressive function. / 12.2019 / PubMed / Full text

CYP11B1

• Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼. / 11.2020 / PubMed / Full text

ALAS1

• Heterozygous disruption of ALAS1 in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver. / 08.12.2020 / PubMed / Full text

HSPA1A

• Vitamin D3 treatment regulates apoptosis, antioxidant defense system, and DNA integrity in the epididymal sperm of an aged rat model. / 12.2019 / PubMed / Full text