Aging genes 10-29: различия между версиями

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* [[Aging genes 1-2‎‎|Genes with 1-2 publications]]
* [[Aging genes 1-2‎‎|Genes with 1-2 publications]]


==MB==
==CCL2==


* {{medline-title
* {{medline-title
|title=Probing menstrual bloodstain aging with fluorescence spectroscopy.
|title=β1 Integrin regulates adult lung alveolar epithelial cell inflammation.
|date=13.11.2020
|date=30.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33279406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31873073
|full-text-url=https://sci-hub.do/10.1016/j.saa.2020.119172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098727
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of physical exercise and medication on enhancing cognitive function in older adults with vascular risk.
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke.
|date=11.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32989840
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008
|full-text-url=https://sci-hub.do/10.1111/ggi.14048
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004
}}
}}
* {{medline-title
* {{medline-title
|title=A novel indenone derivative selectively induces senescence in MDA-[[MB]]-231 (breast adenocarcinoma) cells.
|title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]] accompanied with pro-tumorigenic secretome.
|date=01.11.2020
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32956706
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946
|full-text-url=https://sci-hub.do/10.1016/j.cbi.2020.109250
|full-text-url=https://sci-hub.do/10.1002/ijc.32153
}}
}}
* {{medline-title
* {{medline-title
|title=Improved Autophagic Flux in Escapers from Doxorubicin-Induced Senescence/Polyploidy of Breast Cancer Cells.
|title=Isoflurane anesthesia impairs the expression of immune neuromodulators in the hippocampus of aged mice.
|date=24.08.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32846959
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30571762
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504443
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301699
}}
}}
* {{medline-title
* {{medline-title
|title=Lifespan regulation in α/β posterior neurons of the fly mushroom bodies by Rab27.
|title=Melatonin and inflammation-Story of a double-edged blade.
|date=08.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32627932
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431830
|full-text-url=https://sci-hub.do/10.1111/jpi.12525
}}
}}
* {{medline-title
* {{medline-title
|title=Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells.
|title=Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis.
|date=29.05.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32485849
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025494
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152523
}}
}}
* {{medline-title
* {{medline-title
|title="Mitotic Slippage" and Extranuclear DNA in Cancer Chemoresistance: A Focus on Telomeres.
|title=Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age.
|date=16.04.2020
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32316332
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891542
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215480
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105902
}}
}}
* {{medline-title
* {{medline-title
|title=Diversity of the Senescence Phenotype of Cancer Cells Treated with Chemotherapeutic Agents.
|title=Infiltrating macrophages contribute to age-related neuroinflammation in C57/BL6 mice.
|date=23.11.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771226
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29758231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952928
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.05.003
}}
}}
* {{medline-title
* {{medline-title
|title=Downregulation of the inflammatory network in senescent fibroblasts and aging tissues of the long-lived and cancer-resistant subterranean wild rodent, Spalax.
|title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles.
|date=01.2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31605433
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974727
|full-text-url=https://sci-hub.do/10.1620/tjem.245.29
}}
}}
* {{medline-title
* {{medline-title
|title=Quantification of the health-status of the Dutch Labrador retriever population.
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|date=01.11.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31494529
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|full-text-url=https://sci-hub.do/10.1016/j.prevetmed.2019.104764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
}}
}}
* {{medline-title
* {{medline-title
|title=Conjugated Physiological Resveratrol Metabolites Induce Senescence in Breast Cancer Cells: Role of p53/p21 and p16/Rb Pathways, and ABC Transporters.
|title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort.
|date=11.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441212
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791
|full-text-url=https://sci-hub.do/10.1002/mnfr.201900629
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006
}}
}}
* {{medline-title
* {{medline-title
|title=Reducing interruptions during medication preparation and administration.
|title=Selected life-extending interventions reduce arterial [[CXCL10]] and macrophage colony-stimulating factor in aged mouse arteries.
|date=08.07.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282257
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28390264
|full-text-url=https://sci-hub.do/10.1108/IJHCQA-12-2017-0238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544385
}}
}}
* {{medline-title
* {{medline-title
|title=Different sensitivities of senescent breast cancer cells to immune cell-mediated cytotoxicity.
|title=Strain specificities in cellular and molecular immunopathogenic mechanisms underlying development of experimental autoimmune encephalomyelitis in aged rats.
|date=09.2019
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28284714
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726686
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.03.001
}}
}}
* {{medline-title
* {{medline-title
|title=Immobilization of rubber additive on graphene for high-performance rubber composites.
|title=Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension.
|date=15.08.2019
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31071523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28017665
|full-text-url=https://sci-hub.do/10.1016/j.jcis.2019.05.006
|full-text-url=https://sci-hub.do/10.1016/j.phrs.2016.12.032
}}
}}
* {{medline-title
* {{medline-title
|title=Short and Long-Term Effects of the Exposure of Breast Cancer Cell Lines to Different Ratios of Free or Co-Encapsulated Liposomal Paclitaxel and Doxorubicin.
|title=An attenuated immune response by Schwann cells and macrophages inhibits nerve regeneration in aged rats.
|date=11.04.2019
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30979090
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27459920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523953
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.05.004
}}
}}
* {{medline-title
* {{medline-title
|title=Individual components of the SWI/SNF chromatin remodelling complex have distinct roles in memory neurons of the [i]Drosophila[/i] mushroom body.
|title=Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging.
|date=25.03.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923190
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26973110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451433
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.12.019
}}
}}
* {{medline-title
* {{medline-title
|title=Ginsenoside Rh2 Ameliorates Doxorubicin-Induced Senescence Bystander Effect in Breast Carcinoma Cell MDA-[[MB]]-231 and Normal Epithelial Cell MCF-10A.
|title=Agmatine Ameliorates High Glucose-Induced Neuronal Cell Senescence by Regulating the p21 and p53 Signaling.
|date=12.03.2019
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30871042
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26924930
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429443
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766111
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related histomorphometric and immunohistochemical changes of the moderator band in Egyptian Baladi cattle.
|title=Alterations in Monocyte Phenotypes and Functions after a Hip Fracture in Elderly Individuals: A 6-Month Longitudinal Study.
|date=03.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30588659
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26812523
|full-text-url=https://sci-hub.do/10.1111/ahe.12423
|full-text-url=https://sci-hub.do/10.1159/000443142
}}
}}
* {{medline-title
* {{medline-title
|title=Dynamic Metabolic Response to Adriamycin-Induced Senescence in Breast Cancer Cells.
|title=Elevated Levels of Microbial Translocation Markers and [[CCL2]] Among Older HIV-1-Infected Men.
|date=15.12.2018
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30558288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26494772
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315875
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747622
}}
}}
* {{medline-title
* {{medline-title
|title=Elastin molecular aging promotes MDA-[[MB]]-231 breast cancer cell invasiveness.
|title=[[APOE]] Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration.
|date=09.2018
|date=07.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30186741
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26446211
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120250
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605380
}}
}}
* {{medline-title
* {{medline-title
|title=Antitumor activity of NAX060: A novel semisynthetic berberine derivative in breast cancer cells.
|title=Colorectal cancer-promoting activity of the senescent peritoneal mesothelium.
|date=09.2018
|date=06.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30178609
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26284488
|full-text-url=https://sci-hub.do/10.1002/biof.1440
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745719
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of carnitine palmitoyltransferases on cancer cellular senescence.
|title=Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models.
|date=02.2019
|date=24.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30070697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26235435
|full-text-url=https://sci-hub.do/10.1002/jcp.27042
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2015.07.070
}}
}}
* {{medline-title
* {{medline-title
|title=A miRNAs profile evolution of triple negative breast cancer cells in the presence of a possible adjuvant therapy and senescence inducer.
|title=Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age.
|date=05-06.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003739
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26241743
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524632
}}
}}
* {{medline-title
* {{medline-title
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells.
|title=Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
|date=15.09.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26011191
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444306
}}
}}
* {{medline-title
* {{medline-title
|title=Conditioned medium from stimulated macrophages inhibits growth but induces an inflammatory phenotype in breast cancer cells.
|title=[[CCL2]], [[CXCL8]], [[CXCL9]] and [[CXCL10]] serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees.
|date=10.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25955863
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.06.126
|full-text-url=https://sci-hub.do/10.1111/1756-185X.12589
}}
}}
* {{medline-title
* {{medline-title
|title=TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines.
|title=Senescent dermal fibroblasts enhance stem cell migration through [[CCL2]]/C[[CR2]] axis.
|date=29.03.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596383
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25808810
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979529
|full-text-url=https://sci-hub.do/10.1111/exd.12701
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagic cell death and premature senescence: New mechanism of 5-fluorouracil and sulforaphane synergistic anticancer effect in MDA-[[MB]]-231 triple negative breast cancer cell line.
|title=Age-associated changes in basal NF-κB function in human CD4  T lymphocytes via dysregulation of PI3 kinase.
|date=01.2018
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29104175
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25553802
|full-text-url=https://sci-hub.do/10.1016/j.fct.2017.10.056
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276789
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of DARPP-32 genetic variation on BOLD activation to happy faces.
|title=IL-4 signaling drives a unique arginase /IL-1β  microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Rα after traumatic spinal cord injury.
|date=01.10.2017
|date=25.06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29048604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24966389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069360
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related remodeling of the JAK/STAT/SOCS signaling pathway and associated myocardial changes: From histological to molecular level.
|title=Systemic inflammation impairs attention and cognitive flexibility but not associative learning in aged rats: possible implications for delirium.
|date=11.2017
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782583
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24959140
|full-text-url=https://sci-hub.do/10.1016/j.aanat.2017.07.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050637
}}
}}
==TLR4==
==EGFR==


* {{medline-title
* {{medline-title
|title=Age-Dependent Changes of Adipokine and Cytokine Secretion From Rat Adipose Tissue by Endogenous and Exogenous Toll-Like Receptor Agonists.
|title=Type I Collagen Aging Increases Expression and Activation of [[EGFR]] and Induces Resistance to Erlotinib in Lung Carcinoma in 3D Matrix Model.
|date=2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32973755
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33014812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7466552
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511549
}}
}}
* {{medline-title
* {{medline-title
|title=Role of Toll Like Receptor 4 in Alzheimer's Disease.
|title=Comparative effectiveness and cost-effectiveness of three first-line [[EGFR]]-tyrosine kinase inhibitors: Analysis of real-world data in a tertiary hospital in Taiwan.
|date=2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32983082
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32267879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141611
}}
}}
* {{medline-title
* {{medline-title
|title=Commentary on Some Recent Theses Relevant to Combating Aging: August 2020.
|title=An Optogenetic Method to Study Signal Transduction in Intestinal Stem Cell Homeostasis.
|date=08.2020
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32718230
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32201167
|full-text-url=https://sci-hub.do/10.1089/rej.2020.2378
|full-text-url=https://sci-hub.do/10.1016/j.jmb.2020.03.019
}}
}}
* {{medline-title
* {{medline-title
|title=Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration.
|title=Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway.
|date=2020
|date=13.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32581723
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31935369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146079
}}
}}
* {{medline-title
* {{medline-title
|title=Chemerin facilitates intervertebral disc degeneration via [[TLR4]] and CMKLR1 and activation of NF-kB signaling pathway.
|title=Association between [[EGFR]] mutation and ageing, history of pneumonia and gastroesophageal reflux disease among patients with advanced lung cancer.
|date=11.06.2020
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32526705
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343479
|full-text-url=https://sci-hub.do/10.1016/j.ejca.2019.09.010
}}
}}
* {{medline-title
* {{medline-title
|title=Toll-like receptor 4 differentially regulates adult hippocampal neurogenesis in an age- and sex-dependent manner.
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms.
|date=09.2020
|date=22.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32343455
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237
|full-text-url=https://sci-hub.do/10.1002/hipo.23209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-associated immunosenescence via alterations in splenic immune cell populations in rat.
|title=The role of [[EGFR]] signaling in age-related osteoporosis in mouse cortical bone.
|date=15.01.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31838133
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298955
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.117168
|full-text-url=https://sci-hub.do/10.1096/fj.201900436RR
}}
* {{medline-title
|title=Leptin induces immunosenescence in human B cells.
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31831137
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002206
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Variation in the Magnitude and Longevity of the IgG Subclass Response to a Diphtheria-Tetanus-Acellular Pertussis (DTaP) Vaccine in Mice.
|title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes.
|date=20.09.2019
|date=13.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31547158
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963843
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600
}}
}}
* {{medline-title
* {{medline-title
|title=Rapamycin improves sevoflurane‑induced cognitive dysfunction in aged rats by mediating autophagy through the [[TLR4]]/MyD88/NF‑κB signaling pathway.
|title=[[EGF]]/[[EGF]]R upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence.
|date=10.2019
|date=04.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31432123
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426
}}
}}
* {{medline-title
* {{medline-title
|title=Targeting [[HMGB1]] by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells.
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|date=14.07.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31303606
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660056
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent effect between [[MARCO]] and [[TLR4]] on PMMA particle phagocytosis by macrophages.
|title=Quantum Modeling: A Bridge between the Pumping and Signaling Functions of Na/K-ATPase.
|date=08.2019
|date=09.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225947
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30096926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121303
}}
}}
* {{medline-title
* {{medline-title
|title=Regulation of Toll-Like Receptor (TLR) Signaling Pathway by Polyphenols in the Treatment of Age-Linked Neurodegenerative Diseases: Focus on [[TLR4]] Signaling.
|title=Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer.
|date=2019
|date=30.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31134076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29682186
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522942
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908287
}}
}}
* {{medline-title
* {{medline-title
|title=[[TLR4]] Promotes and DAP12 Limits Obesity-Induced Osteoarthritis in Aged Female Mice.
|title=Withanolide A extends the lifespan in human [[EGFR]]-driven cancerous Caenorhabditis elegans.
|date=04.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044181
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29427754
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478583
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.004
}}
}}
* {{medline-title
* {{medline-title
|title=Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis.
|title=30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Nongenomic effects via the mineralocorticoid receptor.
|date=27.02.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30814582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28348113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393422
|full-text-url=https://sci-hub.do/10.1530/JOE-16-0659
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16 .
|title=Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review.
|date=06.2019
|date=22.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27875990
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120447
}}
}}
* {{medline-title
* {{medline-title
|title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke.
|title=Low-frequency [i]KRAS[/i] mutations are prevalent in lung adenocarcinomas.
|date=04.2019
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27795727
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084916
}}
}}
* {{medline-title
* {{medline-title
|title=Aging leads to dysfunctional innate immune responses to [[TLR2]] and [[TLR4]] agonists.
|title=Association of Polymorphisms in Connective Tissue Growth Factor and Epidermal Growth Factor Receptor Genes With Human Longevity.
|date=09.2019
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30402800
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27365368
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504629
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861942
}}
}}
* {{medline-title
* {{medline-title
|title=Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.
|title=sPLA2 -IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation.
|date=05.2019
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30128650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27299855
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1307-2
|full-text-url=https://sci-hub.do/10.1002/stem.2418
}}
}}
* {{medline-title
* {{medline-title
|title=Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-[[HDAC1]]-mediated regulation of autophagy.
|title=Mechanisms of skin aging induced by [[EGFR]] inhibitors.
|date=06.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660306
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27165055
|full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2018.04.009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611667
}}
}}
* {{medline-title
* {{medline-title
|title=Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging.
|title=Prolactin, [[EGFR]], vimentin and α-actin profiles in elderly rat prostate subjected to steroid hormonal imbalance.
|date=05.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27021728
|full-text-url=https://sci-hub.do/10.1002/cyto.a.23372
|full-text-url=https://sci-hub.do/10.1016/j.tice.2016.03.008
}}
}}
* {{medline-title
* {{medline-title
|title=Inflammation, insulin signaling and cognitive function in aged APP/PS1 mice.
|title=Loss of Maspardin Attenuates the Growth and Maturation of Mouse Cortical Neurons.
|date=05.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26978163
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2018.03.032
|full-text-url=https://sci-hub.do/10.1159/000443666
}}
}}
* {{medline-title
* {{medline-title
|title=Repeated stimulation by LPS promotes the senescence of DPSCs via [[TLR4]]/MyD88-NF-κB-p53/p21 signaling.
|title=Expression profile analysis of new candidate genes for the therapy of primary osteoporosis.
|date=06.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29480340
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26914116
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021280
 
}}
}}
* {{medline-title
* {{medline-title
|title=Ageing potentiates diet-induced glucose intolerance, β-cell failure and tissue inflammation through [[TLR4]].
|title=Selective coexpression of V[[EGF]] receptor 2 in [[EGF]]RvIII-positive glioblastoma cells prevents cellular senescence and contributes to their aggressive nature.
|date=09.02.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29426925
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26420897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827039
}}
}}
* {{medline-title
* {{medline-title
|title=Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice.
|title=Bradykinin inhibits oxidative stress-induced senescence of endothelial progenitor cells through the B2R/AKT/RB and B2R/[[EGFR]]/RB signal pathways.
|date=03.2018
|date=22.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326316
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26360782
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823768
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694787
}}
}}
* {{medline-title
* {{medline-title
|title=Granzyme A in Human Platelets Regulates the Synthesis of Proinflammatory Cytokines by Monocytes in Aging.
|title=First-line gefitinib treatment in elderly patients (aged ≥75 years) with non-small cell lung cancer harboring [[EGFR]] mutations.
|date=01.01.2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26254024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736423
|full-text-url=https://sci-hub.do/10.1007/s00280-015-2841-5
}}
}}
* {{medline-title
* {{medline-title
|title=[[TLR4]] and [[TLR2]] activation is differentially associated with age during Parkinson's disease.
|title=Increased centrosome amplification in aged stem cells of the Drosophila midgut.
|date=01.2018
|date=25.07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29077524
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24971546
|full-text-url=https://sci-hub.do/10.1080/08820139.2017.1379024
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.06.085
}}
}}
* {{medline-title
* {{medline-title
|title=Toll-like receptor 4 ([[TLR4]]) deficient mice are protected from adipose tissue inflammation in aging.
|title=Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain.
|date=07.09.2017
|date=07.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28898202
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24843006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636669
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038845
}}
}}
* {{medline-title
* {{medline-title
|title=Role of pattern recognition receptors of the neurovascular unit in inflamm-aging.
|title=Thiamin concentration in geriatric hospitalized patients using frusemide.
|date=01.11.2017
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28801521
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24597996
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00106.2017
|full-text-url=https://sci-hub.do/10.1080/21551197.2013.875501
}}
}}
==GDF11==
* {{medline-title
* {{medline-title
|title=Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice.
|title=4-Hydroxynonenal impairs transforming growth factor-β1-induced elastin synthesis via epidermal growth factor receptor activation in human and murine fibroblasts.
|date=04.05.2020
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32365331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24561579
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244081
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2014.02.015
}}
}}
==LBP==
* {{medline-title
* {{medline-title
|title=Anti-Aging Effects of [[GDF11]] on Skin.
|title=Lipopolysaccharide binding protein is associated with CVD risk in older adults.
|date=09.04.2020
|date=08.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32283613
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32895891
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177281
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01684-z
}}
}}
* {{medline-title
* {{medline-title
|title=Targeted Approach to Distinguish and Determine Absolute Levels of GDF8 and [[GDF11]] in Mouse Serum.
|title=Aging-related liver degeneration is associated with increased bacterial endotoxin and lipopolysaccharide binding protein levels.
|date=06.2020
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32104967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32090603
|full-text-url=https://sci-hub.do/10.1002/pmic.201900104
|full-text-url=https://sci-hub.do/10.1152/ajpgi.00345.2018
}}
}}
* {{medline-title
* {{medline-title
|title=Growth differentiation factor 11 impairs titanium implant healing in the femur and leads to mandibular bone loss.
|title=Biomarkers of leaky gut are related to inflammation and reduced physical function in older adults with cardiometabolic disease and mobility limitations.
|date=09.2020
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31983062
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654268
|full-text-url=https://sci-hub.do/10.1002/JPER.19-0247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925090
}}
}}
* {{medline-title
* {{medline-title
|title=Systemic [[GDF11]] stimulates the secretion of adiponectin and induces a calorie restriction-like phenotype in aged mice.
|title=Needle-shaped amyloid deposition in rat mammary gland: evidence of a novel amyloid fibril protein.
|date=01.2020
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31637864
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31615282
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974718
|full-text-url=https://sci-hub.do/10.1080/13506129.2019.1675623
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating factors in young blood as potential therapeutic agents for age-related neurodegenerative and neurovascular diseases.
|title=Effects of Lycium barbarum Polysaccharides on Health and Aging of [i]C. elegans[/i] Depend on [i]daf-12/daf-16[/i].
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31400495
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2019.08.004
}}
* {{medline-title
|title=Effects of Exercise Training on Growth and Differentiation Factor 11 Expression in Aged Mice.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31417428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31583041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754959
}}
}}
* {{medline-title
* {{medline-title
|title=[[TERT]] assists [[GDF11]] to rejuvenate senescent VEGFR2 /CD133  cells in elderly patients with myocardial infarction.
|title=Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8.
|date=11.2019
|date=10.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292540
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292465
|full-text-url=https://sci-hub.do/10.1038/s41374-019-0290-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620326
}}
}}
* {{medline-title
* {{medline-title
|title=The role of [[GDF11]] in aging and skeletal muscle, cardiac and bone homeostasis.
|title=Lycium barbarum polysaccharides extend the mean lifespan of Drosophila melanogaster.
|date=04.2019
|date=17.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31144559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259337
|full-text-url=https://sci-hub.do/10.1080/10409238.2019.1610722
|full-text-url=https://sci-hub.do/10.1039/c8fo01751d
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating [[GDF11]] levels are decreased with age but are unchanged with obesity and type 2 diabetes.
|title=Height loss but not body composition is related to low back pain in community-dwelling elderlies: Shimane CoHRE study.
|date=21.03.2019
|date=10.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30897065
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31077175
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461177
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511157
}}
}}
* {{medline-title
* {{medline-title
|title=Activin type II receptor signaling in cardiac aging and heart failure.
|title=Aging of mouse intervertebral disc and association with back pain.
|date=06.03.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842316
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30936040
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549718
}}
}}
* {{medline-title
* {{medline-title
|title=Neuroprotective potential of [[GDF11]] in experimental intracerebral hemorrhage in elderly rats.
|title=A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats.
|date=05.2019
|date=19.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30827882
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30892277
|full-text-url=https://sci-hub.do/10.1016/j.jocn.2019.02.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461166
}}
}}
* {{medline-title
* {{medline-title
|title=The influence of [[GDF11]] on brain fate and function.
|title=Chen-Style Tai Chi for Individuals (Aged 50 Years Old or Above) with Chronic Non-Specific Low Back Pain: A Randomized Controlled Trial.
|date=02.2019
|date=12.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30729414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30759778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423340
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388249
}}
}}
* {{medline-title
* {{medline-title
|title=Administration of r[[GDF11]] retards the aging process in male mice via action of anti-oxidant system.
|title=Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity.
|date=08.2019
|date=11.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30726519
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30713071
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09799-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613828
}}
}}
* {{medline-title
* {{medline-title
|title=Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease.
|title=Factors associated with lumbar disc high-intensity zone (HIZ) on T2-weighted magnetic resonance image: a retrospective study of 3185 discs in 637 patients.
|date=05.2019
|date=04.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514333
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280348
}}
}}
* {{medline-title
* {{medline-title
|title=The Growth Differentiation Factor 11 is Involved in Skin Fibroblast Ageing and is Induced by a Preparation of Peptides and Sugars Derived from Plant Cell Cultures.
|title=Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration [i]in vivo[/i].
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661170
|full-text-url=https://sci-hub.do/10.1007/s12033-019-00154-w
}}
* {{medline-title
|title=[The role of «Youth and aging proteins» in essential hypertension pathogenesis.]
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30584875
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283339
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157327
}}
}}
* {{medline-title
* {{medline-title
|title=Regenerative Capacity of Endogenous Factor: Growth Differentiation Factor 11; a New Approach of the Management of Age-Related Cardiovascular Events.
|title=Use of trunk muscle training and neuromuscular electrical stimulation to reduce pain and disability in an older adult with chronic low back pain: A case report.
|date=12.12.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30545044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617180
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321079
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179941
}}
}}
* {{medline-title
* {{medline-title
|title=Late-onset administration of [[GDF11]] extends life span and delays development of age-related markers in the annual fish Nothobranchius guentheri.
|title=Endotoxemia is modulated by quantity and quality of dietary fat in older adults.
|date=04.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30519861
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129737
|full-text-url=https://sci-hub.do/10.1007/s10522-018-09789-9
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.006
}}
}}
* {{medline-title
* {{medline-title
|title=Growth Differentiation Factor 11 treatment leads to neuronal and vascular improvements in the hippocampus of aged mice.
|title=Correlates of a Recent History of Disabling Low Back Pain in Community-dwelling Older Persons: The Pain in the Elderly (PAINEL) Study.
|date=23.11.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30470794
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29077624
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251885
|full-text-url=https://sci-hub.do/10.1097/AJP.0000000000000564
}}
* {{medline-title
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.
|date=01.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188
}}
}}
* {{medline-title
* {{medline-title
|title=The [[GDF11]]-[[FTO]]-PPARγ axis controls the shift of osteoporotic [[MSC]] fate to adipocyte and inhibits bone formation during osteoporosis.
|title=The Effectiveness and Safety of Manual Therapy on Pain and Disability in Older Persons With Chronic Low Back Pain: A Systematic Review.
|date=12.2018
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29079255
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.09.015
|full-text-url=https://sci-hub.do/10.1016/j.jmpt.2017.06.008
}}
}}
* {{medline-title
* {{medline-title
|title=The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma.
|title=De-educate to re-educate: aging and low back pain.
|date=2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30252623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28275956
|full-text-url=https://sci-hub.do/10.1080/09537104.2018.1514110
|full-text-url=https://sci-hub.do/10.1007/s40520-017-0731-x
}}
}}
* {{medline-title
* {{medline-title
|title=Relationship of muscle function to circulating myostatin, follistatin and [[GDF11]] in older women and men.
|title=Activity of Erector Spinae During Trunk Forward Bending and Backward Return: The Effects of Age.
|date=30.08.2018
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165829
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28194659
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117873
|full-text-url=https://sci-hub.do/10.1007/s10439-017-1811-y
}}
}}
* {{medline-title
* {{medline-title
|title=Activin subfamily peptides predict chronological age in humans.
|title=Global Cysteine-Reactivity Profiling during Impaired Insulin/IGF-1 Signaling in C. elegans Identifies Uncharacterized Mediators of Longevity.
|date=09.2018
|date=18.08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30178598
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27499530
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003114
}}
}}
* {{medline-title
* {{medline-title
|title=Growth differentiation factor 11 worsens hepatocellular injury and liver regeneration after liver ischemia reperfusion injury.
|title=Age- and brain region-dependent α-synuclein oligomerization is attributed to alterations in intrinsic enzymes regulating α-synuclein phosphorylation in aging monkey brains.
|date=09.2018
|date=23.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29913561
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27032368
|full-text-url=https://sci-hub.do/10.1096/fj.201800195R
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890980
}}
}}
* {{medline-title
* {{medline-title
|title=The [i]Drosophila[/i] TGF-beta/Activin-like ligands Dawdle and Myoglianin appear to modulate adult lifespan through regulation of 26S proteasome function in adult muscle.
|title=Association of Lipopolysaccharide-Binding Protein With Aging-Related Adiposity Change and Prediabetes Among African Ancestry Men.
|date=26.04.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615416
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26721818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936056
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764043
}}
}}
==SIRT6==
* {{medline-title
* {{medline-title
|title=Association between [[SIRT6]] Methylation and Human Longevity in a Chinese Population.
|title=Age-related differences in trunk intrinsic stiffness.
|date=25.11.2020
|date=11.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33238266
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26459489
|full-text-url=https://sci-hub.do/10.1159/000508832
|full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2015.09.010
}}
}}
* {{medline-title
* {{medline-title
|title=The [[SIRT6]] activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells.
|title=Probiotics Reduce Inflammation in Antiretroviral Treated, HIV-Infected Individuals: Results of the "Probio-HIV" Clinical Trial.
|date=08.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33089974
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26376436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573418
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva.
|title=The effects of age and gender on the lumbopelvic rhythm in the sagittal plane in 309 subjects.
|date=10.2020
|date=18.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33098511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26294355
|full-text-url=https://sci-hub.do/10.1007/s10517-020-04986-4
|full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2015.07.030
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related epigenetic drift deregulates [i][[SIRT6]][/i] expression and affects its downstream genes in human peripheral blood mononuclear cells.
|title=Does physical activity moderate the relationship between depression symptomatology and low back pain? Cohort and co-twin control analyses nested in the longitudinal study of aging Danish twins (LSADT).
|date=12.2020
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32573339
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26231337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678931
|full-text-url=https://sci-hub.do/10.1007/s00586-015-4138-0
}}
}}
* {{medline-title
* {{medline-title
|title=Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators.
|title=Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans.
|date=07.08.2020
|date=02.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32518153
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25554789
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415977
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425353
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent role of [[SIRT6]] in jawbone via regulating senescence and autophagy of bone marrow stromal cells.
|title=Comparative study of human age estimation with or without preclassification of gender and facial expression.
|date=02.2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32002721
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25295308
|full-text-url=https://sci-hub.do/10.1007/s10735-020-09857-w
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175379
}}
}}
==LPA==
* {{medline-title
* {{medline-title
|title=Mechanism of activation for the sirtuin 6 protein deacylase.
|title=Ginseng gintonin, aging societies, and geriatric brain diseases.
|date=31.01.2020
|date=03.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31822559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32817818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996886
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426447
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomics of Long-Lived Mammals.
|title=Late-life related subtypes of depression - a data-driven approach on cognitive domains and physical frailty.
|date=03.2020
|date=22.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31737995
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32442243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117992
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa110
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuins and [[SIRT6]] in Carcinogenesis and in Diet.
|title=Does sedentary time increase in older adults in the days following participation in intense exercise?
|date=07.10.2019
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31591350
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32130714
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801518
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01502-6
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]]-mediated transcriptional suppression of MALAT1 is a key mechanism for endothelial to mesenchymal transition.
|title=Association of Long-term Exposure to Elevated Lipoprotein(a) Levels With Parental Life Span, Chronic Disease-Free Survival, and Mortality Risk: A Mendelian Randomization Analysis.
|date=15.11.2019
|date=05.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31399301
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32108890
|full-text-url=https://sci-hub.do/10.1016/j.ijcard.2019.07.082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049087
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species.
|title=Elevated Autotaxin and [[LPA]] Levels During Chronic Viral Hepatitis and Hepatocellular Carcinoma Associate with Systemic Immune Activation.
|date=18.04.2019
|date=25.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002797
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31769428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499390
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966516
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] participates in the quality control of aged oocytes via modulating telomere function.
|title=Lysophosphatidic acid receptor [[LPA]] prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome.
|date=29.03.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30926765
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31714004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974717
}}
}}
* {{medline-title
* {{medline-title
|title=LINE1 Derepression in Aged Wild-Type and [[SIRT6]]-Deficient Mice Drives Inflammation.
|title=Associations of Sedentary and Physically-Active Behaviors With Cognitive-Function Decline in Community-Dwelling Older Adults: Compositional Data Analysis From the NEIGE Study.
|date=02.04.2019
|date=05.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30853213
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31656243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449196
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557173
}}
}}
* {{medline-title
* {{medline-title
|title=Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism.
|title=Validation and comparison of two automated methods for quantifying brain white matter hyperintensities of presumed vascular origin.
|date=23.01.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673631
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31612759
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607266
}}
}}
* {{medline-title
* {{medline-title
|title=Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice.
|title=The Sedentary Time and Physical Activity Levels on Physical Fitness in the Elderly: A Comparative Cross Sectional Study.
|date=15.04.2019
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530184
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31581429
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.11.139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801920
}}
}}
* {{medline-title
* {{medline-title
|title=Phosphodiesterase 4 inhibitor activates AMPK-[[SIRT6]] pathway to prevent aging-related adipose deposition induced by metabolic disorder.
|title=Light-Intensity Physical Activity in a Large Prospective Cohort of Older US Adults: A 21-Year Follow-Up of Mortality.
|date=18.09.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30227388
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31600755
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188481
|full-text-url=https://sci-hub.do/10.1159/000502860
}}
}}
* {{medline-title
* {{medline-title
|title=MiR-125b attenuates human hepatocellular carcinoma malignancy through targeting [[SIRT6]].
|title=The Impact of Movement Behaviors on Bone Health in Elderly with Adequate Nutritional Status: Compositional Data Analysis Depending on the Frailty Status.
|date=2018
|date=09.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30034937
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30857291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048406
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472191
}}
}}
* {{medline-title
* {{medline-title
|title=Role of accelerated aging in limb muscle wasting of patients with COPD.
|title=Compositional Influence of Movement Behaviors on Bone Health during Aging.
|date=2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30829961
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820
|full-text-url=https://sci-hub.do/10.1249/MSS.0000000000001972
}}
}}
* {{medline-title
* {{medline-title
|title=A Review of the Recent Advances Made with [[SIRT6]] and its Implications on Aging Related Processes, Major Human Diseases, and Possible Therapeutic Targets.
|title=Duration-Response of Light-Intensity Physical Activity and Glucose Dynamics in Older Adults.
|date=29.06.2018
|date=01.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526273
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164879
|full-text-url=https://sci-hub.do/10.1123/jpah.2017-0557
}}
}}
* {{medline-title
* {{medline-title
|title=Application of multivariate longitudinal models in [[SIRT6]], FBS, and BMI analysis of the elderly.
|title=Accelerometer-Measured Physical Activity and Sedentary Behavior: A Cross-Sectional Study of Brazilian Older Adults.
|date=12.2019
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29901417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336719
|full-text-url=https://sci-hub.do/10.1080/13685538.2018.1477933
|full-text-url=https://sci-hub.do/10.1123/jpah.2017-0456
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuins in Renal Health and Disease.
|title=The Association Between Physical Activity, Including Physical Activity Intensity, and Fear of Falling Differs by Fear Severity in Older Adults Living in the Community.
|date=07.2018
|date=16.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30219902
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939
|full-text-url=https://sci-hub.do/10.1093/geronb/gby103
}}
}}
* {{medline-title
* {{medline-title
|title=Boosting [[ATM]] activity alleviates aging and extends lifespan in a mouse model of progeria.
|title=Gintonin Attenuates D-Galactose-Induced Hippocampal Senescence by Improving Long-Term Hippocampal Potentiation, Neurogenesis, and Cognitive Functions.
|date=02.05.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717979
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30138913
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957528
|full-text-url=https://sci-hub.do/10.1159/000491113
}}
}}
* {{medline-title
* {{medline-title
|title=High expression of CPT1b in skeletal muscle in metabolically healthy older subjects.
|title=Associations of distinct levels of physical activity with mobility in independent healthy older women.
|date=04.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657112
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890269
|full-text-url=https://sci-hub.do/10.1016/j.diabet.2018.01.018
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.06.005
}}
}}
* {{medline-title
* {{medline-title
|title=Haploinsufficiency of [i]Trp53[/i] dramatically extends the lifespan of Sirt6-deficient mice.
|title=Reallocating Accelerometer-Assessed Sedentary Time to Light or Moderate- to Vigorous-Intensity Physical Activity Reduces Frailty Levels in Older Adults: An Isotemporal Substitution Approach in the TSHA Study.
|date=23.02.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29474172
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29269096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825207
|full-text-url=https://sci-hub.do/10.1016/j.jamda.2017.11.003
}}
* {{medline-title
|title=Lean psoas area does not correlate with clinical outcomes in moderately to severely injured older people.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29168295
|full-text-url=https://sci-hub.do/10.1111/ajag.12482
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Genome-wide meta-analysis associates HLA-DQA1/DRB1 and [[LPA]] and lifestyle factors with human longevity.
|date=09.2017
|date=13.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29030599
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715013
}}
}}
* {{medline-title
* {{medline-title
|title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™).
|title=Stress, Depression, Resilience and Ageing: A Role for the [[LPA]]-[[LPA]]1 Pathway.
|date=04.2018
|date=05.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28699486
|full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843979
}}
}}
* {{medline-title
* {{medline-title
|title=Aging as an Epigenetic Phenomenon.
|title=A New Anti-Aging Lysophosphatidic Acid from Arabidopsis thaliana.
|date=10.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28185536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635645
|full-text-url=https://sci-hub.do/10.2174/1573406413666170209124934
}}
}}
==H2AX==
* {{medline-title
* {{medline-title
|title=Evaluation of Gamma[[H2AX]] in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer's Disease in the AIBL Study of Ageing.
|title=Short-duration increases in intraluminal pressure improve vasoconstrictor responses in aged skeletal muscle feed arteries.
|date=06.08.2020
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32781776
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26976132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459751
|full-text-url=https://sci-hub.do/10.1007/s00421-016-3350-x
}}
}}
* {{medline-title
* {{medline-title
|title=Cisplatin-induced peripheral neuropathy is associated to neuronal senescence-like response.
|title=Hearing loss and cognition in the Busselton Baby Boomer cohort: An epidemiological study.
|date=29.06.2020
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32597980
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26915472
|full-text-url=https://sci-hub.do/10.1093/neuonc/noaa151
|full-text-url=https://sci-hub.do/10.1002/lary.25896
}}
}}
* {{medline-title
* {{medline-title
|title=Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites.
|title=The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life.
|date=06.04.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32215662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26569406
|full-text-url=https://sci-hub.do/10.2340/00015555-3473
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646642
}}
}}
* {{medline-title
* {{medline-title
|title=Do BRCA1 and BRCA2 gene mutation carriers have a reduced ovarian reserve? Protocol for a prospective observational study.
|title=Cognitive function in midlife and beyond: physical and cognitive activity related to episodic memory and executive functions.
|date=25.11.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31772111
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25888534
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887091
|full-text-url=https://sci-hub.do/10.1177/0091415015574190
}}
}}
* {{medline-title
* {{medline-title
|title=Slower rates of accumulation of DNA damage in leukocytes correlate with longer lifespans across several species of birds and mammals.
|title=Effect of light and vigorous physical activity on balance and gait of older adults.
|date=15.11.2019
|date=11-12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31730540
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25127848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874430
|full-text-url=https://sci-hub.do/10.1016/j.archger.2014.07.008
}}
}}
* {{medline-title
* {{medline-title
|title=Phosphoproteomic analysis reveals plant DNA damage signalling pathways with a functional role for histone [[H2AX]] phosphorylation in plant growth under genotoxic stress.
|title=Inverse effects of midlife occupational and leisure time physical activity on mobility limitation in old age--a 28-year prospective follow-up study.
|date=12.2019
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31410901
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24731135
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900162
|full-text-url=https://sci-hub.do/10.1111/jgs.12793
}}
}}
==NPY==
* {{medline-title
* {{medline-title
|title=Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress.
|title=Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells.
|date=10.2019
|date=22.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31348603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012215
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243588
}}
}}
* {{medline-title
* {{medline-title
|title=Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging?
|title=Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice.
|date=2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156709
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31855319
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529819
|full-text-url=https://sci-hub.do/10.1111/ggi.13848
}}
}}
* {{medline-title
* {{medline-title
|title=Epigallocatechin-3-gallate induces telomere shortening and clastogenic damage in glioblastoma cells.
|title=Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner.
|date=10.2019
|date=21.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026358
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30899013
|full-text-url=https://sci-hub.do/10.1002/em.22295
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428838
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of [[RNF8]] on cochlear apoptosis and aging in mice of different ages.
|title=β-Alanine supplementation reduces anxiety and increases neurotrophin expression in both young and older rats.
|date=03-Apr,.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915826
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30803507
 
|full-text-url=https://sci-hub.do/10.1016/j.nutres.2018.11.001
}}
}}
* {{medline-title
* {{medline-title
|title=Mitochondrial Protection Partly Mitigates Kidney Cellular Senescence in Swine Atherosclerotic Renal Artery Stenosis.
|title=Age-related central regulation of orexin and [[NPY]] in the short-lived African killifish Nothobranchius furzeri.
|date=2019
|date=15.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30907989
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519989
|full-text-url=https://sci-hub.do/10.1002/cne.24638
}}
}}
* {{medline-title
* {{medline-title
|title=Old age increases microglial senescence, exacerbates secondary neuroinflammation, and worsens neurological outcomes after acute traumatic brain injury in mice.
|title=Chronic treatment with tributyltin induces sexually dimorphic alterations in the hypothalamic [[POMC]] system of adult mice.
|date=05.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30904769
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30078105
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486858
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2896-9
}}
}}
* {{medline-title
* {{medline-title
|title=Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth.
|title=Expression of CGRP neurotransmitter and vascular genesis marker mRNA is age-dependent in superior cervical ganglia of senescence-accelerated prone mice.
|date=01.05.2019
|date=18.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888162
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154859
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b00833
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.11.034
}}
}}
* {{medline-title
* {{medline-title
|title=PFG acted as an inducer of premature senescence in TIG-1 normal diploid fibroblast and an inhibitor of mitosis in the HeLa cells.
|title=Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway.
|date=06.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30836860
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28770437
|full-text-url=https://sci-hub.do/10.1080/09168451.2019.1585744
|full-text-url=https://sci-hub.do/10.1007/s11064-017-2369-7
}}
}}
* {{medline-title
* {{medline-title
|title=[[S100A13]] promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α.
|title=Bioactive growth hormone in older men and women: It's relationship to immune markers and healthspan.
|date=23.01.2019
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30670674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28551577
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366962
|full-text-url=https://sci-hub.do/10.1016/j.ghir.2017.05.002
}}
}}
* {{medline-title
* {{medline-title
|title=Clostridium difficile toxin B induces senescence in enteric glial cells: A potential new mechanism of Clostridium difficile pathogenesis.
|title=Retinal, [[NPY]]- and 5ht- inputs to the aged suprachiasmatic nucleus in common marmosets (Callithrix jacchus).
|date=12.2018
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30296499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28288865
|full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2018.10.007
|full-text-url=https://sci-hub.do/10.1016/j.neures.2017.03.005
}}
}}
* {{medline-title
* {{medline-title
|title=Varenicline reduces DNA damage, tau mislocalization and post surgical cognitive impairment in aged mice.
|title=Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis.
|date=12.2018
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30273594
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28138095
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2018.09.044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374316
}}
}}
* {{medline-title
* {{medline-title
|title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment.
|title=Neuropeptide Y resists excess loss of fat by lipolysis in calorie-restricted mice: a trait potential for the life-extending effect of calorie restriction.
|date=2018
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28101970
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334538
}}
}}
* {{medline-title
* {{medline-title
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|title=Nerve growth factor-induced plasticity in medial prefrontal cortex interneurons of aged Wistar rats.
|date=10.2018
|date=01.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27664582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.09.017
}}
}}
* {{medline-title
* {{medline-title
|title=Acetylation of PGC1α by Histone Deacetylase 1 Downregulation Is Implicated in Radiation-Induced Senescence of Brain Endothelial Cells.
|title=Age Impaired endothelium-dependent vasodilation is improved by resveratrol in rat mesenteric arteries.
|date=16.05.2019
|date=31.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30016403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27298812
|full-text-url=https://sci-hub.do/10.1093/gerona/gly167
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899900
}}
}}
* {{medline-title
* {{medline-title
|title=Role of accelerated aging in limb muscle wasting of patients with COPD.
|title=Age-related changes in neurochemical components and retinal projections of rat intergeniculate leaflet.
|date=2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26718202
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005876
}}
}}
* {{medline-title
* {{medline-title
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA damage and apoptosis in natural ageing rats].
|title=Short photoperiod condition increases susceptibility to stress in adolescent male rats.
|date=04.2018
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751716
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26655789
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180115.005
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2015.12.002
}}
}}
* {{medline-title
* {{medline-title
|title=Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions.
|title=Neuropeptide Y: An Anti-Aging Player?
|date=04.01.2018
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249653
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26549884
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756112
|full-text-url=https://sci-hub.do/10.1016/j.tins.2015.08.012
}}
}}
* {{medline-title
* {{medline-title
|title=Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice.
|title=Influence of Aging and Gender Differences on Feeding Behavior and Ghrelin-Related Factors during Social Isolation in Mice.
|date=15.11.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29141658
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448274
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688691
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598162
}}
}}
* {{medline-title
* {{medline-title
|title=Therapeutic doses of doxorubicin induce premature senescence of human mesenchymal stem cells derived from menstrual blood, bone marrow and adipose tissue.
|title=Reduction in [[NPY]]-positive neurons and dysregulation of excitability in young senescence-accelerated mouse prone 8 (SAMP8) hippocampus precede the onset of cognitive impairment.
|date=03.2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29022209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26250996
|full-text-url=https://sci-hub.do/10.1007/s12185-017-2346-6
|full-text-url=https://sci-hub.do/10.1111/jnc.13274
}}
}}
* {{medline-title
* {{medline-title
|title=Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.
|title=Age effects on the nucleus of the lateral olfactory tract of the rat.
|date=07.10.2017
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26224652
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.08.035
|full-text-url=https://sci-hub.do/10.1002/cne.23863
}}
}}
==TF==
* {{medline-title
* {{medline-title
|title=A preliminary investigation of the contribution of different tenderness factors to beef loin, tri-tip and heel tenderness.
|title=[[NPY]]/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging?
|date=12.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736289
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26086271
|full-text-url=https://sci-hub.do/10.1016/j.meatsci.2020.108247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590601
}}
}}
* {{medline-title
* {{medline-title
|title=The transcription factor ZmNAC126 accelerates leaf senescence downstream of the ethylene signalling pathway in maize.
|title=Analysis of gene expression during aging of CGNs in culture: implication of [[SLIT2]] and [[NPY]] in senescence.
|date=09.2020
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32430911
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26047956
|full-text-url=https://sci-hub.do/10.1111/pce.13803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493715
}}
}}
* {{medline-title
* {{medline-title
|title=Extensive transcriptome changes during seasonal leaf senescence in field-grown black cottonwood (Populus trichocarpa Nisqually-1).
|title=Neuropeptide Y stimulates autophagy in hypothalamic neurons.
|date=20.04.2020
|date=31.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32313054
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25775546
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170949
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386327
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of Transferrin and Albumin in the Sperm-Storage Tubules of Japanese Quail and their Possible Involvement in Long-Term Sperm Storage.
|title=Effect of IP3R3 and [[NPY]] on age-related declines in olfactory stem cell proliferation.
|date=25.01.2020
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32174770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25482245
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315725
}}
}}
* {{medline-title
* {{medline-title
|title=OsWRKY5 Promotes Rice Leaf Senescence via Senescence-Associated NAC and Abscisic Acid Biosynthesis Pathway.
|title=Old-onset caloric restriction effects on neuropeptide Y- and somatostatin-containing neurons and on cholinergic varicosities in the rat hippocampal formation.
|date=09.09.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31505875
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25471895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770167
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259091
}}
}}
* {{medline-title
* {{medline-title
|title=BrTCP7 Transcription Factor Is Associated with MeJA-Promoted Leaf Senescence by Activating the Expression of [i]BrOPR3[/i] and [i]BrRCCR[/i].
|title=Orally administered δ opioid agonist peptide rubiscolin-6 stimulates food intake in aged mice with ghrelin resistance.
|date=14.08.2019
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31416297
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25047666
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719003
|full-text-url=https://sci-hub.do/10.1002/mnfr.201400100
}}
}}
* {{medline-title
* {{medline-title
|title=Activation of the Transcription of [i]BrGA20ox3[/i] by a BrTCP21 Transcription Factor Is Associated with Gibberellin-Delayed Leaf Senescence in Chinese Flowering Cabbage during Storage.
|title=Ghrelin receptor regulates appetite and satiety during aging in mice by regulating meal frequency and portion size but not total food intake.
|date=08.08.2019
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31398806
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24991043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720506
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130825
}}
}}
* {{medline-title
* {{medline-title
|title=Anti-aging effects of long-term space missions, estimated by heart rate variability.
|title=Distribution of peptidergic populations in the human dentate gyrus (somatostatin [SOM-28, SOM-12] and neuropeptide Y [[[NPY]]]) during postnatal development.
|date=20.06.2019
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31222071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24965867
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586662
|full-text-url=https://sci-hub.do/10.1007/s00441-014-1929-2
}}
}}
==ATF4==
* {{medline-title
* {{medline-title
|title=Transgenic expression of rice [[MYB]]102 (Os[[MYB]]102) delays leaf senescence and decreases abiotic stress tolerance in Arabidopsis thaliana.
|title=Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78-Loaded Extracellular Vesicles.
|date=11.2019
|date=10.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31072449
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33297752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889895
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.120.315506
}}
}}
* {{medline-title
* {{medline-title
|title=Tomato fruit ripening factor NOR controls leaf senescence.
|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells.
|date=09.05.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002305
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506771
|full-text-url=https://sci-hub.do/10.1111/pcmr.12811
}}
}}
* {{medline-title
* {{medline-title
|title=The WRKY transcription factor GhWRKY27 coordinates the senescence regulatory pathway in upland cotton (Gossypium hirsutum L.).
|title=Chronic and age-dependent effects of the spongiform neurodegeneration-associated [[MGRN1]] E3 ubiquitin ligase on mitochondrial homeostasis.
|date=29.03.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922232
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089807
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639055
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of cerium oxide nanoparticles on hemostasis: Coagulation, platelets, and vascular endothelial cells.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=07.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30882978
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://sci-hub.do/10.1002/jbm.a.36669
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
* {{medline-title
* {{medline-title
|title=Rice transcription factor Os[[MYB]]102 delays leaf senescence by down-regulating abscisic acid accumulation and signaling.
|title=Effects of a resistance-training programme on endoplasmic reticulum unfolded protein response and mitochondrial functions in PBMCs from elderly subjects.
|date=09.05.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30825376
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30614406
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506775
|full-text-url=https://sci-hub.do/10.1080/17461391.2018.1561950
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=[Protective effect of Wuzi Yanzong recipe on testicular germ cell apoptosis in natural ageing rats through endoplasmic reticulum stress].
|date=15.04.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453716
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180530.001
}}
}}
* {{medline-title
* {{medline-title
|title=Bioinformatic Analysis Reveals Key Genes and Pathways in Aging Brain of Senescence-accelerated Mouse P8 (SAMP8).
|title=Protective effect of Wuzi Yanzong recipe on testicular dysfunction through inhibition of germ cell apoptosis in ageing rats via endoplasmic reticulum stress.
|date=2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30113006
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30393883
|full-text-url=https://sci-hub.do/10.2174/1871527317666180816094741
|full-text-url=https://sci-hub.do/10.1111/and.13181
}}
}}
* {{medline-title
* {{medline-title
|title=Cardiac regenerative capacity is age- and disease-dependent in childhood heart disease.
|title=Loss of NRF-2 and [[PGC]]-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
|date=2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30044800
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30253279
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059427
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156745
}}
}}
* {{medline-title
* {{medline-title
|title=Comparing palm oil tocotrienol rich fraction with α-tocopherol supplementation on oxidative stress in healthy older adults.
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=10.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30014863
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2017.07.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
}}
* {{medline-title
* {{medline-title
|title=The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice.
|title=De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver.
|date=12.06.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891592
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998933
|full-text-url=https://sci-hub.do/10.1530/JME-18-0018
}}
}}
* {{medline-title
* {{medline-title
|title=Comparing Palm Oil, Tocotrienol-Rich Fraction and α-Tocopherol Supplementation on the Antioxidant Levels of Older Adults.
|title=Resveratrol modulates response against acute inflammatory stimuli in aged mouse brain.
|date=28.05.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843393
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29174969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025588
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.014
}}
}}
* {{medline-title
* {{medline-title
|title=Improved synaptic and cognitive function in aged 3 × Tg-AD mice with reduced amyloid-β after immunotherapy with a novel recombinant 6Aβ15-[[TF]] chimeric vaccine.
|title=Integrated stress response stimulates [[FGF21]] expression: Systemic enhancer of longevity.
|date=08.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29803820
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28844867
|full-text-url=https://sci-hub.do/10.1016/j.clim.2018.05.005
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2017.08.009
}}
}}
* {{medline-title
* {{medline-title
|title=Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury.
|title=Role of [[ATF4]] in skeletal muscle atrophy.
|date=01.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29748916
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28376050
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1104-y
|full-text-url=https://sci-hub.do/10.1097/MCO.0000000000000362
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular and functional characterization of ShNAC1, an NAC transcription factor from Solanum habrochaites.
|title=4E-BP is a target of the GCN2-[[ATF4]] pathway during Drosophila development and aging.
|date=06.2018
|date=02.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29650161
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27979906
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2018.03.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223598
}}
}}
* {{medline-title
* {{medline-title
|title=Characterization of a Transcriptional Regulator, BrWRKY6, Associated with Gibberellin-Suppressed Leaf Senescence of Chinese Flowering Cabbage.
|title=Diaminodiphenyl sulfone-induced parkin ameliorates age-dependent dopaminergic neuronal loss.
|date=28.02.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29400954
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27103513
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.7b06085
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.11.008
}}
}}
* {{medline-title
* {{medline-title
|title=Global mapping of transcription factor motifs in human aging.
|title=Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation.
|date=2018
|date=13.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29293662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26961881
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865904
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors.
|title=Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 ([[FGF21]]) in aging mice.
|date=2017
|date=15.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29226156
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26697751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684555
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.12.045
}}
}}
* {{medline-title
* {{medline-title
|title=Cell reprogramming: Therapeutic potential and the promise of rejuvenation for the aging brain.
|title=Unfolded protein response is activated in aged retinas.
|date=11.2017
|date=16.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28903069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26467812
|full-text-url=https://sci-hub.do/10.1016/j.arr.2017.09.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679557
}}
}}
==C3==
* {{medline-title
* {{medline-title
|title=Inverse association between periumbilical fat and longevity mediated by complement [[C3]] and cardiac structure.
|title=Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 ([[ATF4]])-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy.
|date=18.11.2020
|date=16.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33221761
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26338703
|full-text-url=https://sci-hub.do/10.18632/aging.104113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646196
}}
}}
* {{medline-title
* {{medline-title
|title=Complement [[C3]] deficiency ameliorates aging related changes in the kidney.
|title=Effect of mitochondrial stress on systemic metabolism.
|date=01.11.2020
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32882264
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26100439
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118370
|full-text-url=https://sci-hub.do/10.1111/nyas.12822
}}
}}
* {{medline-title
* {{medline-title
|title=Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice.
|title=Senescence may mediate conversion of tau phosphorylation-induced apoptotic escape to neurodegeneration.
|date=04.2020
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32087947
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25777063
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.01.008
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.03.007
}}
}}
* {{medline-title
* {{medline-title
|title=[Comparative analysis of experimental data about the effects of various polyphenols on lifespan and aging.]
|title=Impact of ER stress-regulated [[ATF4]]/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy.
|date=2019
|date=15.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31512417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25567807
 
|full-text-url=https://sci-hub.do/10.1152/ajpcell.00096.2014
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization.
|title=[[ATF4]] activity: a common feature shared by many kinds of slow-aging mice.
|date=01.09.2019
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31325563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25156122
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2019.07.021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326926
}}
}}
* {{medline-title
* {{medline-title
|title=Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus.
|title=The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout.
|date=06.2019
|date=15.09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30656452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25009220
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0607-9
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00511.2013
}}
}}
* {{medline-title
* {{medline-title
|title=[Young and old animals use different strategies for forming an immune response to infectious agents (Pseudomonas aeruginosa и Escherichia coli).]
|title=Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21.
|date=2018
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30584870
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24935677
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331744
}}
}}
* {{medline-title
* {{medline-title
|title=[[TREM2]] triggers microglial density and age-related neuronal loss.
|title=The first international mini-symposium on methionine restriction and lifespan.
|date=03.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548312
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24847356
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023024
}}
}}
* {{medline-title
* {{medline-title
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.
|title=Elevated [[ATF4]] function in fibroblasts and liver of slow-aging mutant mice.
|date=2018
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24691093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351389
}}
}}
==DDT==
* {{medline-title
* {{medline-title
|title=Traumatic Brain Injury in Aged Mice Induces Chronic Microglia Activation, Synapse Loss, and Complement-Dependent Memory Deficits.
|title=Prognostic Value of a Test of Central Auditory Function in Conversion from Mild Cognitive Impairment to Dementia.
|date=26.11.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30486287
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32388503
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321529
|full-text-url=https://sci-hub.do/10.1159/000506621
}}
}}
* {{medline-title
* {{medline-title
|title=Dialdehyde cellulose crosslinked poly(vinyl alcohol) hydrogels: Influence of catalyst and crosslinker shelf life.
|title=Uptake kinetics of four hydrophobic organic pollutants in the earthworm Eisenia andrei in aged laboratory-contaminated natural soils.
|date=15.10.2018
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092989
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061977
|full-text-url=https://sci-hub.do/10.1016/j.carbpol.2018.06.035
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2020.110317
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Feeding Honey Bees (Hymenoptera: Apidae) With Industrial Sugars Produced by Plants Using Different Photosynthetic Cycles (Carbon [[C3]] and C4) on the Colony Wintering Ability, Lifespan, and Forage Behavior.
|title=Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish.
|date=26.09.2018
|date=03-04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29982786
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31911208
|full-text-url=https://sci-hub.do/10.1093/jee/toy189
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061078
}}
}}
* {{medline-title
* {{medline-title
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye.
|title=Second generation effects of larval metal pollutant exposure on reproduction, longevity and insecticide tolerance in the major malaria vector Anopheles arabiensis (Diptera: Culicidae).
|date=13.06.2018
|date=07.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31910892
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947826
}}
}}
* {{medline-title
* {{medline-title
|title=Human Cord Blood Serum-Derived [[APP]] α-Secretase Cleavage Activity is Mediated by C1 Complement.
|title=Protective effect of Pedro-Ximénez must against p,p'-DDE-induced liver damages in aged Mus spretus mice.
|date=04.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29871524
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020233
|full-text-url=https://sci-hub.do/10.1016/j.fct.2019.110984
}}
}}
* {{medline-title
* {{medline-title
|title=Altered gene expression pattern indicates the differential regulation of the immune response system as an important factor in cardiac aging.
|title=Low-dose endosulfan inhibits proliferation and induces senescence and pro-inflammatory cytokine production in human lymphocytes, preferentially impacting cytotoxic cells.
|date=03.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29738791
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589084
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.001
|full-text-url=https://sci-hub.do/10.1080/1547691X.2019.1668513
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix.
|title=DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy.
|date=2018
|date=22.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596429
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875766
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698745
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-related tau astrogliopathy (ARTAG): not only tau phosphorylation in astrocytes.
|title=The contribution of gut bacteria to insecticide resistance and the life histories of the major malaria vector Anopheles arabiensis (Diptera: Culicidae).
|date=11.2018
|date=24.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29396893
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31235803
|full-text-url=https://sci-hub.do/10.1111/bpa.12593
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591418
}}
}}
* {{medline-title
* {{medline-title
|title=A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity.
|title=Exposure to the insecticide-treated bednet PermaNet 2.0 reduces the longevity of the wild African malaria vector Anopheles funestus but GSTe2-resistant mosquitoes live longer.
|date=04.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29408220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30870507
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.01.044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417719
}}
}}
* {{medline-title
* {{medline-title
|title=Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate [[C3]] Batteries.
|title=The occurrence and dynamics of polychlorinated hydrocarbons in roe deer ([i]Capreolus capreolus[/i]) in South-western Slovakia.
|date=2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29188853
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30729857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726304
|full-text-url=https://sci-hub.do/10.1080/10934529.2019.1574152
}}
}}
* {{medline-title
* {{medline-title
|title=Antibodies to Senescent Antigen and [[C3]] Are Not Required for Normal Red Blood Cell Lifespan in a Murine Model.
|title=Insecticide resistance status of three vectors of Japanese encephalitis in east central India.
|date=2017
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163500
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30565276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670101
|full-text-url=https://sci-hub.do/10.1111/mve.12352
}}
}}
* {{medline-title
* {{medline-title
|title=Gut dysbiosis breaks immunological tolerance toward the central nervous system during young adulthood.
|title=Effect of aging on bioaccessibility of [[DDT]]s and PCBs in marine sediment.
|date=31.10.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29078267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30471469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676872
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349416
}}
}}
* {{medline-title
* {{medline-title
|title=Some immunological responses of common carp (Cyprinus carpio) fingerling to acute extremely low-frequency electromagnetic fields (50 Hz).
|title=The effect of commercial herbicide exposure on the life history and insecticide resistance phenotypes of the major malaria vector Anopheles arabiensis (Diptera: culicidae).
|date=02.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29022155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30179608
|full-text-url=https://sci-hub.do/10.1007/s10695-017-0429-1
|full-text-url=https://sci-hub.do/10.1016/j.actatropica.2018.08.030
}}
}}
* {{medline-title
* {{medline-title
|title=Metabolomics of laminae and midvein during leaf senescence and source-sink metabolite management in Brassica napus L. leaves.
|title=Is Chronic Exposure to Low-Dose Organochlorine Pesticides a New Risk Factor of T-cell Immunosenescence?
|date=12.02.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28992054
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853214
|full-text-url=https://sci-hub.do/10.1158/1055-9965.EPI-17-0799
}}
}}
* {{medline-title
* {{medline-title
|title=d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic.
|title=The influence of age on insecticide susceptibility of Anopheles arabiensis during dry and rainy seasons in rice irrigation schemes of Northern Tanzania.
|date=02.12.2017
|date=11.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28965946
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28893240
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594483
}}
}}
* {{medline-title
* {{medline-title
|title=Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model.
|title=DNA damage tolerance in hematopoietic stem and progenitor cells in mice.
|date=2017
|date=15.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928904
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28761001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591916
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565453
}}
}}
==CCK==
* {{medline-title
* {{medline-title
|title=Senolytic agent Quercetin ameliorates intervertebral disc degeneration via the Nrf2/NF-κB axis.
|title=The effects of ingestion of hormonal host factors on the longevity and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae).
|date=23.11.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33242601
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28700639
|full-text-url=https://sci-hub.do/10.1016/j.joca.2020.11.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507448
}}
}}
* {{medline-title
* {{medline-title
|title=Astragalus improve aging bone marrow mesenchymal stem cells (BMSCs) vitality and osteogenesis through VD-FGF23-Klotho axis.
|title=Bioavailability of five hydrophobic organic compounds to earthworms from sterile and non-sterile artificial soils.
|date=2020
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32355520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28371706
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191145
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.03.117
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Age on Acute Appetite-Related Responses to Whey-Protein Drinks, Including Energy Intake, Gastric Emptying, Blood Glucose, and Plasma Gut Hormone Concentrations-A Randomized Controlled Trial.
|title=The effect of elevated temperatures on the life history and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae).
|date=06.04.2020
|date=14.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268554
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28193292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307775
}}
}}
* {{medline-title
* {{medline-title
|title=Lactose induced redox-dependent senescence and activated Nrf2 pathway.
|title=Dichotic Digits Test Performance Across the Ages: Results From Two Large Epidemiologic Cohort Studies.
|date=2019
|date=05-06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31934025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27941404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949649
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404957
}}
}}
* {{medline-title
* {{medline-title
|title=Quercetin Suppresses the Progression of Atherosclerosis by Regulating MST1-Mediated Autophagy in ox-LDL-Induced RAW264.7 Macrophage Foam Cells.
|title=The Role of Oxidative Stress in the Longevity and Insecticide Resistance Phenotype of the Major Malaria Vectors Anopheles arabiensis and Anopheles funestus.
|date=03.12.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816893
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26964046
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786153
}}
}}
* {{medline-title
* {{medline-title
|title=LncRNA AW112010 Promotes Mitochondrial Biogenesis and Hair Cell Survival: Implications for Age-Related Hearing Loss.
|title=Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila.
|date=2019
|date=02.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26787908
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855056
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747718
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of age on feeding response: Focus on the rostral C1 neuron and its glucoregulatory proteins.
|title=Influence of feeding and earthworm density on compound bioaccumulation in earthworms Eisenia andrei.
|date=01.2020
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31705967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26378968
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110779
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2015.09.025
}}
}}
* {{medline-title
* {{medline-title
|title=Ser-Tyr and Asn-Ala, vasorelaxing dipeptides found by comprehensive screening, reduce blood pressure via different age-dependent mechanisms.
|title=Greater cognitive decline with aging among elders with high serum concentrations of organochlorine pesticides.
|date=04.11.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31685714
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26107947
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874431
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480979
}}
}}
* {{medline-title
* {{medline-title
|title=Fisetin, via CKIP-1/REGγ, limits oxidized LDL-induced lipid accumulation and senescence in RAW264.7 macrophage-derived foam cells.
|title=The effect of multiple blood-feeding on the longevity and insecticide resistant phenotype in the major malaria vector Anopheles arabiensis (Diptera: Culicidae).
|date=15.12.2019
|date=23.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31655030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25150975
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2019.172748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161849
}}
}}
* {{medline-title
* {{medline-title
|title=[Ginsenoside Rg_1 induces leukemia stem cell senescence via [[SIRT1]]/TSC_2 signal axis].
|title=The role of canine distemper virus and persistent organic pollutants in mortality patterns of Caspian seals (Pusa caspica).
|date=06.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31359662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24987857
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20190218.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079250
}}
}}
* {{medline-title
* {{medline-title
|title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells.
|title=Solid phase microextraction of organic pollutants from natural and artificial soils and comparison with bioaccumulation in earthworms.
|date=15.07.2019
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24433790
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2013.11.011
}}
}}
==FOXO1==
* {{medline-title
* {{medline-title
|title=Circular RNA expression profile in human fibroblast premature senescence after repeated ultraviolet B irradiations revealed by microarray.
|title=l-Theanine attenuates liver aging by inhibiting advanced glycation end products in d-galactose-induced rats and reversing an imbalance of oxidative stress and inflammation.
|date=08.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30908647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31899338
|full-text-url=https://sci-hub.do/10.1002/jcp.28449
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110823
}}
}}
* {{medline-title
* {{medline-title
|title=Long non-coding RNA-OIS1 inhibits HPV-positive, but not HPV-negative cervical squamous cell carcinoma by upregulating MTK-1.
|title=Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation.
|date=03.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30854069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537739
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365941
|full-text-url=https://sci-hub.do/10.1159/000495895
}}
}}
* {{medline-title
* {{medline-title
|title=Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
|title=Functional pathways regulated by microRNA networks in CD8 T-cell aging.
|date=02.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30674441
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30488559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351841
}}
}}
* {{medline-title
* {{medline-title
|title=MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting [[DLL1]] and Regulating PI3K/AKT Pathway.
|title=Introduction to FOXO Biology.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414140
|full-text-url=https://sci-hub.do/10.1159/000492090
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-8900-3_1
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|title=Antioxidant modifications induced by the new metformin derivative HL156A regulate metabolic reprogramming in SAMP1/kl (-/-) mice.
|date=2018
|date=16.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222592
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188477
}}
}}
* {{medline-title
* {{medline-title
|title=Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/[[SIRT1]] signaling pathway.
|title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls.
|date=06.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475
}}
}}
* {{medline-title
* {{medline-title
|title=Osthole Delays Tert-Butyl Hydroperoxide-Induced Premature Senescence in Neural Stem Cells.
|title=[[FOXO1]] and [[ETV6]] genes may represent novel regulators of splicing factor expression in cellular senescence.
|date=08.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29989446
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088951
|full-text-url=https://sci-hub.do/10.1089/cell.2018.0010
|full-text-url=https://sci-hub.do/10.1096/fj.201801154R
}}
}}
* {{medline-title
* {{medline-title
|title=N-Cadherin Attenuates High Glucose-Induced Nucleus Pulposus Cell Senescence Through Regulation of the ROS/NF-κB Pathway.
|title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging.
|date=2018
|date=25.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768261
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750
|full-text-url=https://sci-hub.do/10.1159/000489804
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052
}}
}}
* {{medline-title
* {{medline-title
|title=Localization of cholecystokinin in the zebrafish retina from larval to adult stage.
|title=FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration.
|date=07.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29679719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963746
|full-text-url=https://sci-hub.do/10.1016/j.aanat.2018.01.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156454
}}
}}
* {{medline-title
* {{medline-title
|title=Glutamate-dependent regulation of food intake is altered with age through changes in NMDA receptor phenotypes on vagal afferent neurons.
|title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation.
|date=15.05.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476874
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058966
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Substitution, and Adding of Carbohydrate and Fat to Whey-Protein on Energy Intake, Appetite, Gastric Emptying, Glucose, Insulin, Ghrelin, [[CCK]] and GLP-1 in Healthy Older Men-A Randomized Controlled Trial.
|title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway.
|date=23.01.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360778
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852689
|full-text-url=https://sci-hub.do/10.1159/000487559
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Age on Blood Glucose and Plasma Insulin, Glucagon, Ghrelin, [[CCK]], [[GIP]], and GLP-1 Responses to Whey Protein Ingestion.
|title=Role of Forkhead Box O (FOXO) transcription factor in aging and diseases.
|date=21.12.2017
|date=30.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29267221
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29428128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793230
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.01.051
}}
}}
* {{medline-title
* {{medline-title
|title=Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation
|title=FOXO in Neural Cells and Diseases of the Nervous System.
|date=27.09.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952292
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433734
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881381
}}
}}
* {{medline-title
* {{medline-title
|title=[Effects of ginseng, notoginseng, and Chuanxiong Rhizoma extracts on cytoskeleton protein of replicative senescence vascular smooth muscle cells].
|title=Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium.
|date=02.2016
|date=11.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28868868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29227245
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160321
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724991
}}
}}
==DBP==
* {{medline-title
* {{medline-title
|title=Do baseline blood pressure and type of exercise influence level of reduction induced by training in hypertensive older adults? A meta-analysis of controlled trials.
|title=FOXO Transcriptional Factors and Long-Term Living.
|date=15.10.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32795629
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894507
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574317
}}
}}
* {{medline-title
* {{medline-title
|title=Attenuated aortic blood pressure responses to metaboreflex activation in older adults with dynapenia.
|title=Aquatide Activation of [[SIRT1]] Reduces Cellular Senescence through a [[SIRT1]]-[[FOXO1]]-Autophagy Axis.
|date=09.2020
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32502600
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822991
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110984
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590795
}}
}}
* {{medline-title
* {{medline-title
|title=The Effect of Blood Pressure on Cognitive Performance. An 8-Year Follow-Up of the Tromsø Study, Comprising People Aged 45-74 Years.
|title=The protein kinase MBK-1 contributes to lifespan extension in [i]daf-2[/i] mutant and germline-deficient [i]Caenorhabditis elegans[/i].
|date=2020
|date=25.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32373010
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28562327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186429
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472741
}}
}}
* {{medline-title
* {{medline-title
|title=Low Diastolic Blood Pressure and Cognitive Decline in Korean Elderly People: The Korean Longitudinal Study on Cognitive Aging and Dementia.
|title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway.
|date=01.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31995969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992855
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465
}}
}}
* {{medline-title
* {{medline-title
|title=Diastolic Blood Pressure Is Associated With Regional White Matter Lesion Load: The Northern Manhattan Study.
|title=Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment.
|date=02.2020
|date=30.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31910743
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28415598
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219602
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482635
}}
}}
* {{medline-title
* {{medline-title
|title=Orthostatic Hypotension and Novel Blood Pressure Associated Gene Variants in Older Adults: Data From the TILDA Study.
|title=Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration.
|date=15.10.2020
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31821404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28430387
|full-text-url=https://sci-hub.do/10.1093/gerona/glz286
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650945
}}
}}
* {{medline-title
* {{medline-title
|title=Blood pressure and hypertension prevalence among oldest-old in China for 16 year: based on CLHLS.
|title=Oxidative Stress-Induced miR-200c Disrupts the Regulatory Loop Among [[SIRT1]], [[FOXO1]], and eNOS.
|date=09.09.2019
|date=20.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27960536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734230
|full-text-url=https://sci-hub.do/10.1089/ars.2016.6643
}}
}}
* {{medline-title
* {{medline-title
|title=The age-related blood pressure trajectories from young-old adults to centenarians: A cohort study.
|title=miR-96, miR-145 and miR-9 expression increases, and IGF-1R and [[FOXO1]] expression decreases in peripheral blood mononuclear cells of aging humans.
|date=01.12.2019
|date=30.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31443986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27903254
|full-text-url=https://sci-hub.do/10.1016/j.ijcard.2019.08.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131432
}}
}}
* {{medline-title
* {{medline-title
|title=Evidence of neurodegeneration in individuals with only mildly elevated blood pressure.
|title=Cone Viability Is Affected by Disruption of Melatonin Receptors Signaling.
|date=12.2019
|date=01.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31246897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26780313
|full-text-url=https://sci-hub.do/10.1097/HJH.0000000000002164
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727519
}}
}}
* {{medline-title
* {{medline-title
|title=Upward resetting of the vascular sympathetic baroreflex in middle-aged male runners.
|title=Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility.
|date=01.07.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31050557
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26762510
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00106.2019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802783
}}
}}
* {{medline-title
* {{medline-title
|title=Fruit, vegetable intake and blood pressure trajectories in older age.
|title=Long live FOXO: unraveling the role of FOXO proteins in aging and longevity.
|date=09.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842546
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26643314
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760602
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783344
}}
}}
* {{medline-title
* {{medline-title
|title=Associations between vitamin D deficiency, musculoskeletal health, and cardiometabolic risk among community-living people in Taiwan: Age and sex-specific relationship.
|title=Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase.
|date=12.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30593197
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26390028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314705
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797648
}}
}}
* {{medline-title
* {{medline-title
|title=Age-differential association between serum uric acid and incident hypertension.
|title=Endogenous ROS levels are increased in replicative senescence in human bone marrow mesenchymal stromal cells.
|date=03.2019
|date=15.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559402
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25839657
|full-text-url=https://sci-hub.do/10.1038/s41440-018-0168-4
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.03.136
}}
}}
==HMGB1==
* {{medline-title
* {{medline-title
|title=Effect of phthalates on development, reproduction, fat metabolism and lifespan in Daphnia magna.
|title=Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction.
|date=01.03.2019
|date=02.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453266
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633821
|full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2018.11.158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885734
}}
}}
* {{medline-title
* {{medline-title
|title=The association between urinary sodium excretion and blood pressure in a community-based population: the Yamagata (Takahata) study.
|title=Targeting [[HMGB1]] by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells.
|date=03.2019
|date=14.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30293215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31303606
|full-text-url=https://sci-hub.do/10.1007/s10157-018-1654-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660056
}}
}}
* {{medline-title
* {{medline-title
|title=Differential Associations of Diastolic and Systolic Pressures With Cerebral Measures in Older Individuals With Mild Cognitive Impairment.
|title=[[HMGB1]] and Caveolin-1 related to [[RPE]] cell senescence in age-related macular degeneration.
|date=13.11.2018
|date=07.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052724
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31284269
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233687
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660032
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related change in thyroid-stimulating hormone: a cross-sectional study in healthy euthyroid population.
|title=Dual faced [[HMGB1]] plays multiple roles in cardiomyocyte senescence and cardiac inflammatory injury.
|date=29.11.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30068892
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31129019
|full-text-url=https://sci-hub.do/10.1507/endocrj.EJ18-0113
|full-text-url=https://sci-hub.do/10.1016/j.cytogfr.2019.05.009
}}
}}
* {{medline-title
* {{medline-title
|title=[Association between blood pressure related dietary patterns and identified cognitive performance in the elderly Chinese-a study by reduced rank regression method].
|title=Neuroprotective Effect of Dioscin on the Aging Brain.
|date=10.06.2018
|date=30.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29936747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30935017
|full-text-url=https://sci-hub.do/10.3760/cma.j.issn.0254-6450.2018.06.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479446
}}
}}
* {{medline-title
* {{medline-title
|title=Optimal Blood Pressure in Elderly Hypertensive Subjects: A Korean National Health Insurance Service Health Examinee Cohort Study.
|title=Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging.
|date=03.08.2018
|date=23.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29767674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30903794
|full-text-url=https://sci-hub.do/10.1093/ajh/hpy081
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461165
}}
}}
* {{medline-title
* {{medline-title
|title=Inter-relationship between ageing, body mass index, diabetes, systemic blood pressure and intraocular pressure in Asians: 6-year longitudinal study.
|title=Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis.
|date=02.2019
|date=30.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632002
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30910981
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500153
}}
}}
* {{medline-title
* {{medline-title
|title=Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks.
|title=Serum and nutrient deprivation increase autophagic flux in intervertebral disc annulus fibrosus cells: an in vitro experimental study.
|date=05-06.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29554514
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30847707
|full-text-url=https://sci-hub.do/10.1016/j.archger.2018.03.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538458
}}
}}
* {{medline-title
* {{medline-title
|title=Association of regular walking and body mass index on metabolic syndrome among an elderly Korean population.
|title=Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
|date=06.2018
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29522861
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735837
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.03.004
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.02.005
}}
}}
* {{medline-title
* {{medline-title
|title=Blood Pressure Trajectories in the 20 Years Before Death.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=01.01.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29204655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833502
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
* {{medline-title
* {{medline-title
|title=Determinants of carotid-femoral pulse wave velocity progression in hypertensive patients over a 3.7 years follow-up.
|title=Repeated abortion in adulthood induces cognition impairment in aged mice.
|date=02.2018
|date=30.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28922954
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061639
|full-text-url=https://sci-hub.do/10.1080/08037051.2017.1378069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065382
}}
}}
* {{medline-title
* {{medline-title
|title=Associations between Greenness, Impervious Surface Area, and Nighttime Lights on Biomarkers of Vascular Aging in Chennai, India.
|title=Loss of DNA polymerase β induces cellular senescence.
|date=02.08.2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28886599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29968395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783666
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203593
}}
}}
==CD34==
* {{medline-title
* {{medline-title
|title=Comparing the Effect of TGF-β Receptor Inhibition on Human Perivascular Mesenchymal Stromal Cells Derived from Endometrium, Bone Marrow and Adipose Tissues.
|title=Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of [[BDNF]]/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
|date=01.12.2020
|date=06.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33271899
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29065194
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712261
|full-text-url=https://sci-hub.do/10.1093/ntr/ntx157
}}
}}
* {{medline-title
* {{medline-title
|title=ACE2/ACE imbalance and impaired vasoreparative functions of stem/progenitor cells in aging.
|title=Intestinal Permeability Biomarker Zonulin is Elevated in Healthy Aging.
|date=27.11.2020
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33247425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694587
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581307
}}
}}
* {{medline-title
* {{medline-title
|title=Innovative Mind-Body Intervention Day Easy Exercise Increases Peripheral Blood [[CD34]]  Cells in Adults.
|title=Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging.
|date=01-12.2020
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32841054
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28317237
|full-text-url=https://sci-hub.do/10.1177/0963689720952352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418188
}}
}}
* {{medline-title
* {{medline-title
|title=Human Thymic Involution and Aging in Humanized Mice.
|title=Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women.
|date=2020
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32733465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28316011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358581
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514208
}}
}}
* {{medline-title
* {{medline-title
|title=Coinhibition of activated p38 MAPKα and mTORC1 potentiates stemness maintenance of HSCs from SR1-expanded human cord blood [[CD34]] cells via inhibition of senescence.
|title=Systemic [[HMGB1]] Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats.
|date=12.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32602209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27822212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695631
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075578
}}
}}
* {{medline-title
* {{medline-title
|title=Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype.
|title=The Alarmin [[HMGB1]] Mediates Age-Induced Neuroinflammatory Priming.
|date=09.2020
|date=27.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27466339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396301
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961779
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal stem cells repair bone marrow damage of aging rats and regulate autophagy and aging genes.
|title=Human fetal membranes at term: Dead tissue or signalers of parturition?
|date=08.2020
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32432372
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27452431
|full-text-url=https://sci-hub.do/10.1002/cbf.3548
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375105
}}
}}
* {{medline-title
* {{medline-title
|title=Immune cell extracellular vesicles and their mitochondrial content decline with ageing.
|title=Modulation of Macrophage Polarization and [[HMGB1]]-TLR2/[[TLR4]] Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice.
|date=2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31911808
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27070323
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942666
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829159
}}
}}
* {{medline-title
* {{medline-title
|title=Young and elderly oral squamous cell carcinoma patients present similar angiogenic profile and predominance of M2 macrophages: Comparative immunohistochemical study.
|title=DAMPs and influenza virus infection in ageing.
|date=12.2019
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31497915
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26200296
|full-text-url=https://sci-hub.do/10.1002/hed.25954
|full-text-url=https://sci-hub.do/10.1016/j.arr.2015.07.005
}}
}}
* {{medline-title
* {{medline-title
|title=HIV-mediated immune aging in young adults infected perinatally or during childhood.
|title=Decreased serum level of [[HMGB1]] and MyD88 during human aging progress in healthy individuals.
|date=01.09.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31149945
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26130428
|full-text-url=https://sci-hub.do/10.1097/QAD.0000000000002275
|full-text-url=https://sci-hub.do/10.1007/s40520-015-0402-8
}}
}}
* {{medline-title
* {{medline-title
|title=Immunophenotypic characterization, multi-lineage differentiation and aging of zebrafish heart and liver tissue-derived mesenchymal stem cells as a novel approach in stem cell-based therapy.
|title=[Peptides and [[[[CCL1]]1]] and [[HMGB1]] as molecular markers of aging: literature review and own data].
|date=04.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30947959
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826983
|full-text-url=https://sci-hub.do/10.1016/j.tice.2019.01.006
 
}}
}}
* {{medline-title
* {{medline-title
|title=Cardio-ankle vascular index and circulating [[CD34]]-positive cell levels as indicators of endothelial repair activity in older Japanese men.
|title=[[HMGB1]] facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice.
|date=06.2019
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30920121
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25510912
|full-text-url=https://sci-hub.do/10.1111/ggi.13657
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309669
}}
}}
* {{medline-title
* {{medline-title
|title=Role of apoptotic, autophagic and senescence pathways in minor salivary gland adenoid cystic carcinoma.
|title=Secondhand smoke exposure-induced nucleocytoplasmic shuttling of [[HMGB1]] in a rat premature skin aging model.
|date=08.02.2019
|date=02.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30736793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25446104
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368765
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.11.040
}}
}}
* {{medline-title
* {{medline-title
|title=Dynamic regulation of [[NOTCH1]] activation and Notch ligand expression in human thymus development.
|title=Changes in the expression of the Toll-like receptor system in the aging rat kidneys.
|date=13.08.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30042180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810370
|full-text-url=https://sci-hub.do/10.1242/dev.165597
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014502
}}
}}
* {{medline-title
* {{medline-title
|title=Therapeutic efficacy of olfactory stem cells in rotenone induced Parkinsonism in adult male albino rats.
|title=Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating [[CD200]]-[[CD200]]R interaction involve the cannabinoid system.
|date=07.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29864896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24588829
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.04.160
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157566
}}
}}
==KL==
* {{medline-title
* {{medline-title
|title=Gender and age-related cell compositional differences in C57BL/6 murine adipose tissue stromal vascular fraction.
|title=The goddess who spins the thread of life: Klotho, psychiatric stress, and accelerated aging.
|date=2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29882687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224190
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660403
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence.
|title=[i][[KL]]OTHO[/i] heterozygosity attenuates [i]APOE4[/i]-related amyloid burden in preclinical AD.
|date=09.2018
|date=16.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29851177
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30867273
|full-text-url=https://sci-hub.do/10.1002/cbin.10999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550504
}}
* {{medline-title
|title=Precise Intradermal Injection of Nanofat-Derived Stromal Cells Combined with Platelet-Rich Fibrin Improves the Efficacy of Facial Skin Rejuvenation.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768259
|full-text-url=https://sci-hub.do/10.1159/000489809
}}
}}
* {{medline-title
* {{medline-title
|title=Human nail stem cells are retained but hypofunctional during aging.
|title=Utilizing Atlas-Based Modeling to Predict Knee Joint Cartilage Degeneration: Data from the Osteoarthritis Initiative.
|date=06.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29633149
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30547410
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942356
|full-text-url=https://sci-hub.do/10.1007/s10439-018-02184-y
}}
}}
* {{medline-title
* {{medline-title
|title=Hair Follicle Stem Cell Faith Is Dependent on Chromatin Remodeling Capacity Following Low-Dose Radiation.
|title=Impaired proteostasis in senescent vascular endothelial cells: a perspective on estrogen and oxidative stress in the aging vasculature.
|date=04.2018
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29282803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30499713
|full-text-url=https://sci-hub.do/10.1002/stem.2768
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00318.2018
}}
}}
* {{medline-title
* {{medline-title
|title=Developmental differences between neonatal and adult human erythropoiesis.
|title=Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis.
|date=08.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29274096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30488497
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842122
|full-text-url=https://sci-hub.do/10.1002/em.22247
}}
}}
* {{medline-title
* {{medline-title
|title=Normal variation of bone marrow B-cell precursors according to age - reference ranges for studies in myelodysplastic syndromes in Brazil.
|title=Klotho at the Edge of Alzheimer's Disease and Senile Depression.
|date=09.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29205788
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978424
|full-text-url=https://sci-hub.do/10.1002/cyto.b.21604
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1200-z
}}
}}
* {{medline-title
* {{medline-title
|title=Aging process, adherence to Mediterranean diet and nutritional status in a large cohort of nonagenarians: Effects on endothelial progenitor cells.
|title=Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity.
|date=01.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167060
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890178
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.09.003
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.002
}}
}}
* {{medline-title
* {{medline-title
|title=Lower resting and exercise-induced circulating angiogenic progenitors and angiogenic T cells in older men.
|title=G-395A polymorphism in the promoter region of the [[KL]]OTHO gene associates with frailty among the oldest-old.
|date=01.03.2018
|date=30.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167123
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712948
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00592.2017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928057
}}
}}
==IGF1==
* {{medline-title
* {{medline-title
|title=Genetic differences and longevity-related phenotypes influence lifespan and lifespan variation in a sex-specific manner in mice.
|title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling.
|date=11.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33105070
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393
}}
}}
* {{medline-title
* {{medline-title
|title=17α-estradiol modulates [[IGF1]] and hepatic gene expression in a sex-specific manner.
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|date=28.08.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32857104
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa215
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
}}
}}
* {{medline-title
* {{medline-title
|title=Pan-mammalian analysis of molecular constraints underlying extended lifespan.
|title=Anti-aging factor, serum alpha-Klotho, as a marker of acute physiological stress, and a predictor of ICU mortality, in patients with septic shock.
|date=11.02.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32043462
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29268200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012612
|full-text-url=https://sci-hub.do/10.1016/j.jcrc.2017.11.023
}}
}}
* {{medline-title
* {{medline-title
|title=17α-Estradiol promotes ovarian aging in growth hormone receptor knockout mice, but not wild-type littermates.
|title=Secreted αKlotho isoform protects against age-dependent memory deficits.
|date=01.2020
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31698046
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29086766
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911620
|full-text-url=https://sci-hub.do/10.1038/mp.2017.211
}}
}}
* {{medline-title
* {{medline-title
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading.
|title=Induction of anti-aging gene klotho with a small chemical compound that demethylates CpG islands.
|date=05.2020
|date=18.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28657902
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564520
}}
}}
* {{medline-title
* {{medline-title
|title=Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging?
|title=Longevity Klotho gene polymorphism and the risk of dementia in older men.
|date=2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156709
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28539162
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529819
|full-text-url=https://sci-hub.do/10.1016/j.maturitas.2017.04.005
}}
}}
* {{medline-title
* {{medline-title
|title=Lactoferrin ameliorates aging-suppressed osteogenesis via [[IGF1]] signaling.
|title=Klotho, APOEε4, cognitive ability, brain size, atrophy, and survival: a study in the Aberdeen Birth Cohort of 1936.
|date=07.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31125976
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28431289
|full-text-url=https://sci-hub.do/10.1530/JME-19-0003
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.02.019
}}
}}
* {{medline-title
* {{medline-title
|title=[i][[TP53]][/i] Tumor-suppressor Gene Plays a Key Role in [[IGF1]] Signaling Pathway Related to the Aging of Human Melanocytes.
|title=The relevance of α-[[KL]]OTHO to the central nervous system: Some key questions.
|date=05.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092438
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28323064
|full-text-url=https://sci-hub.do/10.21873/anticanres.13363
|full-text-url=https://sci-hub.do/10.1016/j.arr.2017.03.003
}}
}}
* {{medline-title
* {{medline-title
|title=Involvement of insulin receptor substrates in cognitive impairment and Alzheimer's disease.
|title=Systemic klotho is associated with [[KL]]OTHO variation and predicts intrinsic cortical connectivity in healthy human aging.
|date=08.2019
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30964050
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27714549
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382127
}}
}}
* {{medline-title
* {{medline-title
|title=In mice transgenic for [[IGF1]] under keratin-14 promoter, lifespan is decreased and the rates of aging and thymus involution are accelerated.
|title=Activation of [[SIRT1]] Attenuates Klotho Deficiency-Induced Arterial Stiffness and Hypertension by Enhancing AMP-Activated Protein Kinase Activity.
|date=13.04.2019
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30981207
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27620389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503882
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063709
}}
}}
* {{medline-title
* {{medline-title
|title=[[IGF1]] Gene Therapy Modifies Microglia in the Striatum of Senile Rats.
|title=The [[FGF23]]/[[KL]]OTHO Regulatory Network and Its Roles in Human Disorders.
|date=2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890930
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27125741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411822
|full-text-url=https://sci-hub.do/10.1016/bs.vh.2016.02.001
}}
}}
* {{medline-title
* {{medline-title
|title=Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease.
|title=Antiaging Gene Klotho Deficiency Promoted High-Fat Diet-Induced Arterial Stiffening via Inactivation of AMP-Activated Protein Kinase.
|date=05.2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26781278
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752379
}}
}}
* {{medline-title
* {{medline-title
|title=Growth signaling and longevity in mouse models.
|title=[[KL]]-optimal experimental design for discriminating between two growth models applied to a beef farm.
|date=01.2019
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30545442
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26776261
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386229
|full-text-url=https://sci-hub.do/10.3934/mbe.2016.13.67
}}
}}
* {{medline-title
* {{medline-title
|title=IGF-1 Gene Therapy as a Potentially Useful Therapy for Spontaneous Prolactinomas in Senile Rats.
|title=Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease Progression.
|date=2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30198429
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26599613
|full-text-url=https://sci-hub.do/10.2174/1566523218666180905170020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658185
}}
}}
* {{medline-title
* {{medline-title
|title=A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup.
|title=Genetic Variants in [[KL]]OTHO Associate With Cognitive Function in the Oldest Old Group.
|date=12.2018
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30151729
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26405063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294728
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978356
}}
}}
* {{medline-title
* {{medline-title
|title=Matrine induces senescence of human glioblastoma cells through suppression of the [[IGF1]]/PI3K/AKT/p27 signaling pathway.
|title=N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models.
|date=09.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30079478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25860694
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393098
}}
}}
* {{medline-title
* {{medline-title
|title=Composition and richness of the serum microbiome differ by age and link to systemic inflammation.
|title=Senescence-inducible LE[[C2]] enhances triacylglycerol accumulation in leaves without negatively affecting plant growth.
|date=06.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29869736
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25790072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448714
}}
}}
* {{medline-title
* {{medline-title
|title=40 YEARS of [[IGF1]]: [[IGF1]]: the Jekyll and Hyde of the aging brain.
|title=Molecular basis of Klotho: from gene to function in aging.
|date=07.2018
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29739805
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25695404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988994
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399270
}}
}}
* {{medline-title
* {{medline-title
|title=De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver.
|title=Life extension factor klotho enhances cognition.
|date=05.2018
|date=22.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24813892
|full-text-url=https://sci-hub.do/10.1530/JME-18-0018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176932
}}
}}
==TFAM==
* {{medline-title
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training.
|date=03.2018
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857
}}
}}
* {{medline-title
* {{medline-title
|title=Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans.
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|date=03.2018
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29522556
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862515
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
}}
}}
* {{medline-title
* {{medline-title
|title=Withanolide A extends the lifespan in human [[EGFR]]-driven cancerous Caenorhabditis elegans.
|title=Differences in Liver [[TFAM]] Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats.
|date=04.2018
|date=27.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29427754
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31137890
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566948
}}
}}
* {{medline-title
* {{medline-title
|title=Caloric restriction stabilizes body weight and accelerates behavioral recovery in aged rats after focal ischemia.
|title=Photobiomodulation and Coenzyme Q  Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice.
|date=12.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28961383
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676058
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular signatures of longevity: Insights from cross-species comparative studies.
|title=[A study on alterations in mitochondrial biological characteristics during cellular senescence of human embryonic lung fibroblasts].
|date=10.2017
|date=06.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28800931
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30841673
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807068
|full-text-url=https://sci-hub.do/10.3760/cma.j.issn.0253-9624.2019.03.014
}}
}}
==MIP==
* {{medline-title
* {{medline-title
|title=Inspiratory muscle training improves cerebrovascular and postural control responses during orthostatic stress in older women.
|title=Changes in Stemness Properties, Differentiation Potential, Oxidative Stress, Senescence and Mitochondrial Function in Wharton's Jelly Stem Cells of Umbilical Cords of Mothers with Gestational Diabetes Mellitus.
|date=10.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32705393
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30645713
|full-text-url=https://sci-hub.do/10.1007/s00421-020-04441-2
|full-text-url=https://sci-hub.do/10.1007/s12015-019-9872-y
}}
}}
* {{medline-title
* {{medline-title
|title=A novel multi-marker discovery approach identifies new serum biomarkers for Parkinson's disease in older people: an EXosomes in PArkiNson Disease (EXPAND) ancillary study.
|title=Cycling CD4  T cells in HIV-infected immune nonresponders have mitochondrial dysfunction.
|date=10.2020
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32458283
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525911
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205369
}}
}}
* {{medline-title
* {{medline-title
|title=Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning.
|title=Increased [[TFAM]] binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart.
|date=08.2020
|date=20.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32387511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29969715
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416443
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319621
}}
}}
* {{medline-title
* {{medline-title
|title=Comparison of balance changes after inspiratory muscle or Otago exercise training.
|title=Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice.
|date=2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31978126
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29745022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980667
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052475
}}
}}
* {{medline-title
* {{medline-title
|title=[i]Lactobacillus acidophilus[/i] DDS-1 Modulates Intestinal-Specific Microbiota, Short-Chain Fatty Acid and Immunological Profiles in Aging Mice.
|title=Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/[[PGC]]-1α pathway.
|date=07.06.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31181695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325933
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627711
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820139
}}
}}
* {{medline-title
* {{medline-title
|title=Systemic inflammation contributes to impairment of quality of life in chronic pancreatitis.
|title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers.
|date=13.05.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31086257
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513859
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022
}}
}}
* {{medline-title
* {{medline-title
|title=Open Mouth-Maximal Isometric Press: Development and Norms for Clinical Swallowing Evaluations and Treatment.
|title=Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats.
|date=21.02.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31072163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807823
|full-text-url=https://sci-hub.do/10.1044/2018_AJSLP-18-0137
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.017
}}
}}
* {{medline-title
* {{medline-title
|title=A New Understanding of the Role of IL-1 in Age-Related Intervertebral Disc Degeneration in a Murine Model.
|title=Effect of lifelong football training on the expression of muscle molecular markers involved in healthy longevity.
|date=08.2019
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30875127
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28251397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697204
|full-text-url=https://sci-hub.do/10.1007/s00421-017-3562-8
}}
}}
* {{medline-title
* {{medline-title
|title=Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis.
|title=Regulation of mitochondrial gene expression, the epigenetic enigma.
|date=27.02.2019
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30814582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199194
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393422
|full-text-url=https://sci-hub.do/10.2741/4535
}}
}}
* {{medline-title
* {{medline-title
|title=Inflammation and Monocyte Recruitment due to Aging and Mechanical Stretch in Alveolar Epithelium are Inhibited by the Molecular Chaperone 4-phenylbutyrate.
|title=Poor embryo development in post-ovulatory in vivo-aged mouse oocytes is associated with mitochondrial dysfunction, but mitochondrial transfer from somatic cells is not sufficient for rejuvenation.
|date=12.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30581495
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27591230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301058
|full-text-url=https://sci-hub.do/10.1093/humrep/dew203
}}
}}
* {{medline-title
* {{medline-title
|title=Prophylactic Palmitoylethanolamide Prolongs Survival and Decreases Detrimental Inflammation in Aged Mice With Bacterial Meningitis.
|title=Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice.
|date=2018
|date=05.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30505308
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27597651
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250830
|full-text-url=https://sci-hub.do/10.1016/j.mce.2016.09.001
}}
}}
* {{medline-title
* {{medline-title
|title=Establishment of a lethal aged mouse model of human respiratory syncytial virus infection.
|title="What makes some rats live so long?" The mitochondrial contribution to longevity through balance of mitochondrial dynamics and mtDNA content.
|date=01.2019
|date=01.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27620821
|full-text-url=https://sci-hub.do/10.1016/j.antiviral.2018.11.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922457
}}
}}
* {{medline-title
* {{medline-title
|title=Mitochondrial DNA variants and pulmonary function in older persons.
|title=Response of [[BAX]], Bcl-2 Proteins, and [[SIRT1]]/[[PGC]]-1α mRNA Expression to 8-Week Treadmill Running in the Aging Rat Skeletal Muscle.
|date=01.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30508565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27526155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356103
|full-text-url=https://sci-hub.do/10.1007/978-3-319-38810-6_38
}}
}}
* {{medline-title
* {{medline-title
|title=Respiratory Muscle Strength as a Discriminator of Sarcopenia in Community-Dwelling Elderly: A Cross-Sectional Study.
|title=Methylene blue improves sensorimotor phenotype and decreases anxiety in parallel with activating brain mitochondria biogenesis in mid-age mice.
|date=2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30272099
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27515402
|full-text-url=https://sci-hub.do/10.1007/s12603-018-1079-4
|full-text-url=https://sci-hub.do/10.1016/j.neures.2016.07.006
}}
}}
* {{medline-title
* {{medline-title
|title=The Role of Pulmonary and Systemic Immunosenescence in Acute Lung Injury.
|title=HIF-1 regulates insect lifespan extension by inhibiting c-Myc-[[TFAM]] signaling and mitochondrial biogenesis.
|date=08.2018
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30090646
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27469241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065297
|full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2016.07.007
}}
}}
* {{medline-title
* {{medline-title
|title=Cortical and hippocampal expression of inflammatory and intracellular signaling proteins in aged rats submitted to aerobic and resistance physical training.
|title=Resistance exercise training and in vitro skeletal muscle oxidative capacity in older adults.
|date=09.2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29958998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27405968
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.06.025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945835
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Changes to Human Tear Composition.
|title=Mitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disorders.
|date=01.04.2018
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29677365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27387767
|full-text-url=https://sci-hub.do/10.1167/iovs.17-23358
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183306
}}
}}
* {{medline-title
* {{medline-title
|title=Sex Differences in Adipose Tissue CD8  T Cells and Regulatory T Cells in Middle-Aged Mice.
|title=Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of [[INS]]-1 cells through Pim-1.
|date=2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29670627
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27049278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893719
 
}}
}}
* {{medline-title
* {{medline-title
|title=Reaction time in healthy elderly is associated with chronic low-grade inflammation and advanced glycation end product.
|title=Regulation of mitochondrial biogenesis through [[TFAM]]-mitochondrial DNA interactions: Useful insights from aging and calorie restriction studies.
|date=15.07.2018
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29630924
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26437364
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.04.002
|full-text-url=https://sci-hub.do/10.1016/j.mito.2015.10.001
}}
}}
* {{medline-title
* {{medline-title
|title=Inspiratory muscle training improves physical performance and cardiac autonomic modulation in older women.
|title=Dietary Tocotrienol/γ-Cyclodextrin Complex Increases Mitochondrial Membrane Potential and ATP Concentrations in the Brains of Aged Mice.
|date=06.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29549494
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26301044
|full-text-url=https://sci-hub.do/10.1007/s00421-018-3844-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537756
}}
}}
* {{medline-title
* {{medline-title
|title=Cerebrospinal Fluid and Plasma Levels of Inflammation Differentially Relate to CNS Markers of Alzheimer's Disease Pathology and Neuronal Damage.
|title=A comparison among the tissue-specific effects of aging and calorie restriction on [[TFAM]] amount and [[TFAM]]-binding activity to mtDNA in rat.
|date=2018
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29439331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24631828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007886
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335656
}}
}}
* {{medline-title
* {{medline-title
|title=Skeletal Muscle Injury Biomarkers: Assay Qualification Efforts and Translation to the Clinic.
|title=Partial reversal of skeletal muscle aging by restoration of normal NAD⁺ levels.
|date=10.2017
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29162011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24410488
|full-text-url=https://sci-hub.do/10.1177/0192623317738927
|full-text-url=https://sci-hub.do/10.1089/rej.2014.1546
}}
}}
* {{medline-title
==ASL==
|title=Brainstem cytokine changes in healthy ageing and Motor Neurone Disease.
|date=15.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28991679
|full-text-url=https://sci-hub.do/10.1016/j.jns.2017.08.013
}}
* {{medline-title
|title=Validity of maximum isometric tongue pressure as a screening test for physical frailty: Cross-sectional study of Japanese community-dwelling older adults.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28868806
|full-text-url=https://sci-hub.do/10.1111/ggi.13166
}}
==PINK1==


* {{medline-title
* {{medline-title
|title=Spermidine inhibits neurodegeneration and delays aging via the [[PINK1]]-PDR1-dependent mitophagy pathway in [i]C. elegans[/i].
|title=Increased blood-brain barrier permeability to water in the aging brain detected using noninvasive multi-TE [[ASL]] MRI.
|date=09.09.2020
|date=01.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32902411
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32910547
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521492
|full-text-url=https://sci-hub.do/10.1002/mrm.28496
}}
}}
* {{medline-title
* {{medline-title
|title=Female mice are resilient to age-related decline of substantia nigra dopamine neuron firing parameters.
|title=Quantitative Cerebrovascular Reactivity in Normal Aging: Comparison Between Phase-Contrast and Arterial Spin Labeling MRI.
|date=11.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32846275
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411174
}}
}}
* {{medline-title
* {{medline-title
|title=Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration.
|title=Correcting Task fMRI Signals for Variability in Baseline CBF Improves BOLD-Behavior Relationships: A Feasibility Study in an Aging Model.
|date=09.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32749068
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32425745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511865
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205008
}}
}}
* {{medline-title
* {{medline-title
|title=SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via [[PINK1]]-dependent mitophagy.
|title=Cerebral Blood Flow in Community-Based Older Twins Is Moderately Heritable: An Arterial Spin Labeling Perfusion Imaging Study.
|date=18.07.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32687063
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31333444
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615405
}}
}}
* {{medline-title
* {{medline-title
|title=Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster.
|title=A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure.
|date=23.09.2020
|date=15.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32386191
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31062904
|full-text-url=https://sci-hub.do/10.1515/jcim-2019-0136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693488
}}
}}
* {{medline-title
* {{medline-title
|title=Compression-induced senescence of nucleus pulposus cells by promoting mitophagy activation via the [[PINK1]]/PARKIN pathway.
|title=Cortical cerebral blood flow in ageing: effects of haematocrit, sex, ethnicity and diabetes.
|date=05.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32281308
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30887200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214186
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719435
}}
}}
* {{medline-title
* {{medline-title
|title=Doxorubicin-induced normal breast epithelial cellular aging and its related breast cancer growth through mitochondrial autophagy and oxidative stress mitigated by ginsenoside Rh2.
|title=Exercise-stimulated arterial transit time in calf muscles measured by dynamic contrast-enhanced magnetic resonance imaging.
|date=07.2020
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32100342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30648355
|full-text-url=https://sci-hub.do/10.1002/ptr.6636
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333626
}}
}}
* {{medline-title
* {{medline-title
|title=Mitochondrial DNA heteroplasmy rises in substantial nigra of aged [[PINK1]] KO mice.
|title=Impact of Coffee, Wine, and Chocolate Consumption on Cognitive Outcome and MRI Parameters in Old Age.
|date=22.01.2020
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31727366
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30275380
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.10.112
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212945
}}
}}
* {{medline-title
* {{medline-title
|title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training.
|title=Potential Role of OERP as Early Marker of Mild Cognitive Impairment.
|date=01.10.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30271339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146232
}}
}}
* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Reduced Regional Cerebral Blood Flow Relates to Poorer Cognition in Older Adults With Type 2 Diabetes.
|date=04.07.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30250430
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139361
}}
}}
* {{medline-title
* {{medline-title
|title=Neuronal Mitophagy: Lessons from a Pathway Linked to Parkinson's Disease.
|title=The Age-Related Perfusion Pattern Measured With Arterial Spin Labeling MRI in Healthy Subjects.
|date=08.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102068
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30065646
|full-text-url=https://sci-hub.do/10.1007/s12640-019-00060-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056623
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of the deubiquitinase [[USP8]] corrects a Drosophila [[PINK1]] model of mitochondria dysfunction.
|title=Resilience and amygdala function in older healthy and depressed adults.
|date=04.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29754022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467245
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995579
}}
}}
* {{medline-title
* {{medline-title
|title=Oligonol Alleviates Sarcopenia by Regulation of Signaling Pathways Involved in Protein Turnover and Mitochondrial Quality.
|title=Does Aerobic Exercise Influence Intrinsic Brain Activity? An Aerobic Exercise Intervention among Healthy Old Adults.
|date=05.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30793867
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28848424
|full-text-url=https://sci-hub.do/10.1002/mnfr.201801102
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554511
}}
}}
* {{medline-title
* {{medline-title
|title=AMP Kinase Activation is Selectively Disrupted in the Ventral Midbrain of Mice Deficient in Parkin or [[PINK1]] Expression.
|title=Cerebral blood flow and vasoreactivity in aging: an arterial spin labeling study.
|date=03.2019
|date=23.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30411223
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28355354
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394446
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423749
}}
}}
* {{medline-title
* {{medline-title
|title=Intensified mitophagy in skeletal muscle with aging is downregulated by [[PGC]]-1alpha overexpression in vivo.
|title=Cerebral blood flow measured by arterial spin labeling MRI at resting state in normal aging and Alzheimer's disease.
|date=01.2019
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30395971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27908711
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.10.456
|full-text-url=https://sci-hub.do/10.1016/j.neubiorev.2016.11.023
}}
}}
* {{medline-title
* {{medline-title
|title=Melatonin protects chronic kidney disease mesenchymal stem cells against senescence via PrP  -dependent enhancement of the mitochondrial function.
|title=Cerebral blood flow MRI in the nondemented elderly is not predictive of post-operative delirium but is correlated with cognitive performance.
|date=01.2019
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30372554
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27401806
|full-text-url=https://sci-hub.do/10.1111/jpi.12535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453459
}}
}}
* {{medline-title
* {{medline-title
|title=[[PRKN]]-regulated mitophagy and cellular senescence during COPD pathogenesis.
|title=Improving drug retention in liposomes by aging with the aid of glucose.
|date=03.2019
|date=30.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30290714
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27021465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351145
|full-text-url=https://sci-hub.do/10.1016/j.ijpharm.2016.03.044
}}
}}
* {{medline-title
* {{medline-title
|title=Grape skin extract improves muscle function and extends lifespan of a Drosophila model of Parkinson's disease through activation of mitophagy.
|title=The Utility of Cerebral Blood Flow as a Biomarker of Preclinical Alzheimer's Disease.
|date=11.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30248358
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26898552
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.09.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278904
}}
}}
* {{medline-title
* {{medline-title
|title=Imaging mitophagy in the fruit fly.
|title=Long-term effect of orthokeratology on the anterior segment length.
|date=2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26905786
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135567
|full-text-url=https://sci-hub.do/10.1016/j.clae.2016.02.003
}}
}}
* {{medline-title
* {{medline-title
|title=Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease.
|title=Comparison of long-labeled pseudo-continuous arterial spin labeling ([[ASL]]) features between young and elderly adults: special reference to parameter selection.
|date=2018
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29947276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26893213
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372017
|full-text-url=https://sci-hub.do/10.1177/0284185116632387
}}
}}
* {{medline-title
* {{medline-title
|title=[[PINK1]] protects against oxidative stress induced senescence of human nucleus pulposus cells via regulating mitophagy.
|title=Assessing intracranial vascular compliance using dynamic arterial spin labeling.
|date=02.10.2018
|date=01.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890141
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26364865
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.06.031
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651759
}}
}}
* {{medline-title
* {{medline-title
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i].
|title=Lens Position and Age: The Central India Eye and Medical Study.
|date=29.05.2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26258615
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047
|full-text-url=https://sci-hub.do/10.1167/iovs.15-16796
}}
}}
* {{medline-title
* {{medline-title
|title=[[ATF3]] represses [[PINK1]] gene transcription in lung epithelial cells to control mitochondrial homeostasis.
|title=Age-related changes in brain hemodynamics; A calibrated MRI study.
|date=04.2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29363258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26177724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869092
}}
}}
* {{medline-title
* {{medline-title
|title=In vivo imaging reveals mitophagy independence in the maintenance of axonal mitochondria during normal aging.
|title=Characterizing the white matter hyperintensity penumbra with cerebral blood flow measures.
|date=10.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782874
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26106546
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595681
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473817
}}
}}
==SI==
* {{medline-title
* {{medline-title
|title=Microarray Profiling Reveals Distinct Circulating miRNAs in Aged Male and Female Mice Subjected to Post-stroke Social Isolation.
|title=Tissue specific arterial spin labeling fMRI: a superior method for imaging cerebral blood flow in aging and disease.
|date=19.10.2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33074466
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25571530
|full-text-url=https://sci-hub.do/10.1007/s12017-020-08622-2
|full-text-url=https://sci-hub.do/10.1109/EMBC.2014.6945162
}}
}}
* {{medline-title
* {{medline-title
|title=Is Heart Rate a Confounding Factor for Photoplethysmography Markers? A Systematic Review.
|title=Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster.
|date=10.04.2020
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32290168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24567903
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929909
}}
}}
==BRCA1==
* {{medline-title
* {{medline-title
|title=Survival time after marked reduction in oral intake in terminally ill noncancer patients: A retrospective study.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=03.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32161695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060293
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
* {{medline-title
* {{medline-title
|title=Adherence to Mediterranean diet moderates the association between multimorbidity and depressive symptoms in older adults.
|title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair.
|date=05-06.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109694
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828
|full-text-url=https://sci-hub.do/10.1016/j.archger.2020.104022
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001
}}
}}
* {{medline-title
* {{medline-title
|title=Loneliness, Social Isolation, and Objectively Measured Physical Activity in Rural-Living Older Adults.
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|date=19.12.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31860831
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|full-text-url=https://sci-hub.do/10.1123/japa.2019-0027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
}}
}}
* {{medline-title
* {{medline-title
|title=The associations between social support and negative social interaction with suicidal ideation in US Chinese older adults.
|title=Klotho gene polymorphisms are associated with healthy aging and longevity: Evidence from a meta-analysis.
|date=25.10.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31650846
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30633899
|full-text-url=https://sci-hub.do/10.1080/13607863.2019.1680953
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.12.003
}}
}}
* {{medline-title
* {{medline-title
|title=Cell Senescence and Cerebral Small Vessel Disease in the Brains of People Aged 80 Years and Older.
|title=High expression of the breast cancer susceptibility gene [[BRCA1]] in long-lived termite kings.
|date=01.11.2019
|date=11.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31553444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30312170
|full-text-url=https://sci-hub.do/10.1093/jnen/nlz088
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224230
}}
}}
* {{medline-title
* {{medline-title
|title=Clinical findings associated with development of postoperative reflux and short-term survival after small intestinal surgery in geriatric and mature nongeriatric horses.
|title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment.
|date=07.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002397
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328
|full-text-url=https://sci-hub.do/10.1111/vsu.13217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527
}}
}}
* {{medline-title
* {{medline-title
|title=Saving inventory - Revised: Psychometric performance across the lifespan.
|title=Cost effectiveness of population based [[BRCA1]] founder mutation testing in Sephardi Jewish women.
|date=01.06.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30999092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294600
|full-text-url=https://sci-hub.do/10.1016/j.ajog.2017.12.221
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of aerobic fitness on cognitive performance as a function of dual-task demands in older adults.
|title=Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions.
|date=04.2019
|date=04.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249653
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756112
}}
}}
* {{medline-title
* {{medline-title
|title=Predictors of neurodegeneration differ between cognitively normal and subsequently impaired older adults.
|title=Faulty [[BRCA1]], [[BRCA2]] genes: how poor is the prognosis?
|date=03.2019
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30580127
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29017890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394867
|full-text-url=https://sci-hub.do/10.1016/j.annepidem.2017.09.005
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in interstitial fibrosis and germ cell degeneration of the canine testis.
|title=Ovarian Aging in Women With BRCA Germline Mutations.
|date=11.2018
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30474336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28938488
|full-text-url=https://sci-hub.do/10.1111/rda.13354
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630253
}}
}}
* {{medline-title
* {{medline-title
|title=Total energy intake according to the level of skeletal muscle mass in Korean adults aged 30 years and older: an analysis of the Korean National Health and Nutrition Examination Surveys (KNHANES) 2008-2011.
|title=The expected benefit of preventive mastectomy on breast cancer incidence and mortality in BRCA mutation carriers, by age at mastectomy.
|date=06.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29854328
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28914396
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974068
|full-text-url=https://sci-hub.do/10.1007/s10549-017-4476-1
}}
}}
* {{medline-title
* {{medline-title
|title=Differences in response inhibition processes between adolescents and adults are modulated by sensory processes.
|title=A [[BRCA1]]-Dependent DNA Damage Response in the Regenerating Adult Peripheral Nerve Milieu.
|date=06.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730536
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28585187
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969207
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0574-7
}}
}}
* {{medline-title
* {{medline-title
|title=The role of plant size in the selection of glyphosate resistance in Sorghum halepense.
|title=The Histone Variant MacroH2A1 Is a [[BRCA1]] Ubiquitin Ligase Substrate.
|date=11.2018
|date=30.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577596
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28564596
|full-text-url=https://sci-hub.do/10.1002/ps.4923
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507409
}}
}}
* {{medline-title
* {{medline-title
|title=Age Effect on Automatic Inhibitory Function of the Somatosensory and Motor Cortex: An MEG Study.
|title=A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer.
|date=2018
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29551971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840154
|full-text-url=https://sci-hub.do/10.1016/j.jval.2017.01.006
}}
}}
* {{medline-title
* {{medline-title
|title=Gender differences in health expenditure determinants: A follow-up study.
|title=Serum [[AMH]] levels in healthy women from [[BRCA1]]/2 mutated families: are they reduced?
|date=01.2019
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29494785
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27907901
|full-text-url=https://sci-hub.do/10.1080/07399332.2018.1445252
|full-text-url=https://sci-hub.do/10.1093/humrep/dew242
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation.
|title=p16INK4a suppresses [[BRCA1]]-deficient mammary tumorigenesis.
|date=30.01.2018
|date=20.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29382344
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27811360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356676
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of age and diet on glucose and insulin dynamics in the horse.
|title=BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries.
|date=09.2018
|date=03.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29356053
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552356
|full-text-url=https://sci-hub.do/10.1111/evj.12812
|full-text-url=https://sci-hub.do/10.1080/10495398.2016.1210613
}}
}}
* {{medline-title
* {{medline-title
|title=Do the antecedents and consequences of loneliness change from middle adulthood into old age?
|title=Women's preferences for contralateral prophylactic mastectomy: An  investigation using protection motivation theory.
|date=01.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154641
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27529090
|full-text-url=https://sci-hub.do/10.1037/dev0000453
|full-text-url=https://sci-hub.do/10.1016/j.pec.2015.11.012
}}
}}
* {{medline-title
* {{medline-title
|title=Self-initiated spatial working memory in young and older adults.
|title=Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome.
|date=05.2018
|date=15.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29169298
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26943589
|full-text-url=https://sci-hub.do/10.1080/09658211.2017.1402938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914261
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Gene [i]act[/i]A on the Invasion Efficiency of [i]Listeria monocytogenes[/i], as Observed in Healthy and Senescent Intestinal Epithelial Cells.
|title=Genetic suppression reveals DNA repair-independent antagonism between [[BRCA1]] and COBRA1 in mammary gland development.
|date=28.01.2018
|date=04.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29121703
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26941120
|full-text-url=https://sci-hub.do/10.4014/jmb.1710.10026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785232
}}
}}
* {{medline-title
* {{medline-title
|title=[Effect of resveratrol on forelimb grip strength and myofibril structure in aged rats].
|title=Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and [[BRCA1]]-mediated DNA repair.
|date=20.10.2017
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29070475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26414677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661791
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of age and dietary carbohydrate profiles on glucose and insulin dynamics in horses.
|title=Comparative proteomic analysis of primordial follicles from ovaries of immature and aged rats.
|date=03.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28833406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391928
|full-text-url=https://sci-hub.do/10.1111/evj.12745
|full-text-url=https://sci-hub.do/10.3109/19396368.2015.1077903
}}
}}
==FOXO3==
* {{medline-title
* {{medline-title
|title=The DNA methylation of [[FOXO3]] and TP53 as a blood biomarker of late-onset asthma.
|title=BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging.
|date=09.12.2020
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33298101
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26224004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726856
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710189
}}
}}
* {{medline-title
* {{medline-title
|title=[[FOXO3]] targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16  increase.
|title=Increased DNA damage and repair deficiency in granulosa cells are associated with ovarian aging in rhesus monkey.
|date=11.2020
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33156570
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25957622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531862
}}
}}
* {{medline-title
* {{medline-title
|title=Astaxanthin as a Putative Geroprotector: Molecular Basis and Focus on Brain Aging.
|title=Conservation of pro-longevity genes among mammals.
|date=05.07.2020
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32635607
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25804384
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457664
}}
}}
* {{medline-title
* {{medline-title
|title=Inflamma-miR-21 Negatively Regulates Myogenesis during Ageing.
|title=Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells.
|date=23.04.2020
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32340146
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24747666
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222422
|full-text-url=https://sci-hub.do/10.1093/gerona/glu019
}}
}}
==C5==
* {{medline-title
* {{medline-title
|title=Variable DNA methylation of aging-related genes is associated with male COPD.
|title=The [[C5]]-75 Program: Meeting the Need for Efficient, Pragmatic Frailty Screening and Management in Primary Care.
|date=04.11.2019
|date=23.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31684967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32638663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829949
|full-text-url=https://sci-hub.do/10.1017/S0714980820000161
}}
}}
* {{medline-title
* {{medline-title
|title=A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster.
|title=Can a relatively large spinal cord for the dural sac influence severity of paralysis in elderly patients with cervical spinal cord injury caused by minor trauma?
|date=08.2019
|date=26.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31415568
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32590805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328921
}}
}}
* {{medline-title
* {{medline-title
|title=[[FOXO3]] on the Road to Longevity: Lessons From SNPs and Chromatin Hubs.
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.
|date=2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31303978
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606898
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829
}}
}}
* {{medline-title
* {{medline-title
|title=Longevity-Associated Forkhead Box O3 ([[FOXO3]]) Single Nucleotide Polymorphisms are Associated with Type 2 Diabetes Mellitus in Chinese Elderly Women.
|title=Longevity of adenovirus vector immunity in mice and its implications for vaccine efficacy.
|date=22.04.2019
|date=29.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009445
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30266488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489531
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200586
}}
}}
* {{medline-title
* {{medline-title
|title=Signal Transduction, Ageing and Disease.
|title=Generating Rasch-based activity of daily living measures from the Spinal Cord Injury Longitudinal Aging Study.
|date=2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28895574
|full-text-url=https://sci-hub.do/10.1007/978-981-13-3681-2_9
|full-text-url=https://sci-hub.do/10.1038/sc.2017.99
}}
}}
* {{medline-title
* {{medline-title
|title=[[FOXO3]], a Molecular Search for the Fountain of Youth.
|title=A Large Cohort Study of 18F Fluoro-Deoxy-Glucose Uptake in Normal Spinal Cord: Quantitative Assessment of the Contamination From Adjacent Vertebral Marrow Uptake and Validity of Normalizing the Cord Uptake Against the Lumbar Thecal Sac.
|date=07.03.2019
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30849363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27560019
|full-text-url=https://sci-hub.do/10.1016/j.stem.2019.02.008
|full-text-url=https://sci-hub.do/10.1097/RCT.0000000000000479
}}
}}
* {{medline-title
* {{medline-title
|title=10-year follow-up of the Super-Seniors Study: compression of morbidity and genetic factors.
|title=Demographic aspects in cervical vertebral bodies' size and shape ([[C3]]-[[C7]]): a skeletal study.
|date=28.02.2019
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30819100
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27544049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394013
|full-text-url=https://sci-hub.do/10.1016/j.spinee.2016.08.022
}}
}}
* {{medline-title
* {{medline-title
|title=Taste receptors, innate immunity and longevity: the case of [[TAS2R16]] gene.
|title=Tract-specific and age-related variations of the spinal cord microstructure: a multi-parametric MRI study using diffusion tensor imaging (DTI) and inhomogeneous magnetization transfer (ihMT).
|date=2019
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30833980
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27100385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387736
|full-text-url=https://sci-hub.do/10.1002/nbm.3530
}}
}}
* {{medline-title
* {{medline-title
|title=[[FOXO3]]-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration.
|title=Age-related brain atrophy may be mitigated by internal jugular vein enlargement in male individuals without neurologic disease.
|date=07.03.2019
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661960
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26911619
|full-text-url=https://sci-hub.do/10.1016/j.stem.2018.12.002
|full-text-url=https://sci-hub.do/10.1177/0268355516633610
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of [[FOXO3]] Gene Polymorphisms Associated with Human Longevity.
|title=The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis.
|date=2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414160
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26834465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716725
}}
}}
* {{medline-title
* {{medline-title
|title=Recent advances in understanding the role of [[FOXO3]].
|title=Signal intensity loss of the intervertebral discs in the cervical spine of young patients on fluid sensitive sequences.
|date=2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228872
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26634254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717169
}}
}}
* {{medline-title
* {{medline-title
|title=FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration.
|title=Are the standard parameters of cervical spine alignment and range of motion related to age, sex, and cervical disc degeneration?
|date=10.2018
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963746
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26091436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156454
|full-text-url=https://sci-hub.do/10.3171/2015.1.SPINE14489
}}
}}
* {{medline-title
* {{medline-title
|title=The longevity SNP rs2802292 uncovered: [[HSF1]] activates stress-dependent expression of [[FOXO3]] through an intronic enhancer.
|title=DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease.
|date=20.06.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733381
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25933409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009585
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416920
}}
}}
* {{medline-title
* {{medline-title
|title=Minimal Shortening of Leukocyte Telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated [[FOXO3]] Allele.
|title=Permeability and shear modulus of articular cartilage in growing mice.
|date=08.10.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29688278
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25847455
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175018
|full-text-url=https://sci-hub.do/10.1007/s10237-015-0671-3
}}
}}
* {{medline-title
* {{medline-title
|title=FOXO in Neural Cells and Diseases of the Nervous System.
|title=Acute exercise increases hippocampal [[TNF]]-α, Caspase-3 and Caspase-7 expression in healthy young and older mice.
|date=2018
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433734
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25853879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881381
 
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Variation in [[FOXO3]] is Associated with Self-Rated Health in a Population-Based Sample of Older Individuals.
|title=Age influences inflammatory responses, hemodynamics, and cardiac proteasome activation during acute lung injury.
|date=08.10.2018
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415201
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25844693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806788
}}
}}
* {{medline-title
* {{medline-title
|title=Identification and characterization of two functional variants in the human longevity gene [[FOXO3]].
|title=Minocycline enhances hippocampal memory, neuroplasticity and synapse-associated proteins in aged [[C5]]7 BL/6 mice.
|date=12.12.2017
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234056
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25838119
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727304
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2015.03.003
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of [[FOXO3]] Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies.
|title=Presence of rd8 mutation does not alter the ocular phenotype of late-onset retinal degeneration mouse model.
|date=08.10.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28977569
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25814825
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360165
}}
}}
* {{medline-title
* {{medline-title
|title=FOXO Transcriptional Factors and Long-Term Living.
|title=Concentration- and age-dependent effects of chronic caffeine on contextual fear conditioning in [[C5]]7BL/6J mice.
|date=2017
|date=01.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25827925
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574317
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586291
}}
}}
==CD38==
* {{medline-title
* {{medline-title
|title=Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction.
|title=Miglitol protects against age-dependent weight gain in mice: A potential role of increased U[[CP]]1 content in brown adipose tissue.
|date=02.11.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32935380
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25833077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604620
|full-text-url=https://sci-hub.do/10.1507/endocrj.EJ15-0116
}}
}}
* {{medline-title
* {{medline-title
|title=TNFRSF12A and [[CD38]] Contribute to a Vicious Circle for Chronic Obstructive Pulmonary Disease by Engaging Senescence Pathways.
|title=Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice.
|date=2020
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32537452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268922
|full-text-url=https://sci-hub.do/10.1016/j.patbio.2015.03.002
}}
}}
* {{medline-title
* {{medline-title
|title=Aging alters acetylation status in skeletal and cardiac muscles.
|title=A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging.
|date=06.2020
|date=20.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32300965
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25839158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286993
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496166
}}
}}
* {{medline-title
* {{medline-title
|title=[[CD38]] in Neurodegeneration and Neuroinflammation.
|title=Anti-skin ageing activity of napthoquinones from Arnebia nobilis Reichb.f.
|date=18.02.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32085567
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25810219
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072759
|full-text-url=https://sci-hub.do/10.1080/14786419.2015.1025232
}}
}}
* {{medline-title
* {{medline-title
|title=[[CD38]], a Receptor with Multifunctional Activities: From Modulatory Functions on Regulatory Cell Subsets and Extracellular Vesicles, to a Target for Therapeutic Strategies.
|title=Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture.
|date=27.11.2019
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783629
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25797136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953043
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.03.009
}}
}}
* {{medline-title
* {{medline-title
|title=[[CD38]] Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD /Sirt1 Signaling Pathway.
|title=Age-associated oxidative modifications of mitochondrial α-subunit of F1 ATP synthase from mouse skeletal muscles.
|date=2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31551807
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25790938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735286
|full-text-url=https://sci-hub.do/10.3109/10715762.2015.1017477
}}
}}
* {{medline-title
* {{medline-title
|title=The Multi-faceted Ecto-enzyme [[CD38]]: Roles in Immunomodulation, Cancer, Aging, and Metabolic Diseases.
|title=Videofluoroscopic Validation of a Translational Murine Model of Presbyphagia.
|date=2019
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31214171
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25783697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555258
|full-text-url=https://sci-hub.do/10.1007/s00455-015-9604-7
}}
}}
==COMT==
* {{medline-title
* {{medline-title
|title=Interacting NAD  and Cell Senescence Pathways Complicate Antiaging Therapies.
|title=The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain.
|date=06.2019
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32008855
|full-text-url=https://sci-hub.do/10.1089/rej.2019.2218
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.12.018
}}
}}
* {{medline-title
* {{medline-title
|title=The NADase [[CD38]] is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD  decline.
|title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.
|date=28.05.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975470
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486859
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608707
}}
}}
* {{medline-title
* {{medline-title
|title=Measuring [[CD38]] Hydrolase and Cyclase Activities: 1,N -Ethenonicotinamide Adenine Dinucleotide (ε-NAD) and Nicotinamide Guanine Dinucleotide (NGD) Fluorescence-based Methods.
|title=Frontoparietal cortical thickness mediates the effect of [[COMT]] Val Met polymorphism on age-associated executive function.
|date=20.07.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30112426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30342271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251730
}}
}}
* {{medline-title
* {{medline-title
|title=The Plasma NAD  Metabolome Is Dysregulated in "Normal" Aging.
|title=[MELATONIN: THE POSSIBILITY TO ANALYSE THE MARKER OF AGE-RELATED PATHOLOGY IN THE BUCCAL EPITHELIUM AND URINE].
|date=04.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30124109
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30303666
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482912
 
}}
}}
* {{medline-title
* {{medline-title
|title=Assays for NAD -Dependent Reactions and NAD  Metabolites.
|title=The Moderating Role of [[COMT]] and [[BDNF]] Polymorphisms on Transfer Effects Following Multi- and Single-Domain Cognitive Training Among Community-Dwelling Shanghainese Older Adults.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097862
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30026692
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041383
}}
}}
* {{medline-title
* {{medline-title
|title=Decreased NAD Activates [[STAT3]] and Integrin Pathways to Drive Epithelial-Mesenchymal Transition.
|title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.
|date=10.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29980616
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481
}}
}}
* {{medline-title
* {{medline-title
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|title=Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.
|date=05.07.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29637543
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105503
}}
}}
* {{medline-title
* {{medline-title
|title=Abnormalities of age-related T cell senescence in Parkinson's disease.
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=28.05.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29807534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972443
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
}}
* {{medline-title
* {{medline-title
|title=A Potent and Specific [[CD38]] Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD  Decline.
|title=A genetic variant in the catechol-O-methyl transferase ([[COMT]]) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers.
|date=01.05.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28746172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935140
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627798
}}
}}
* {{medline-title
* {{medline-title
|title=Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes.
|title=Catechol-O-Methyltransferase Genotype and Gait Speed Changes over 10 Years in Older Adults.
|date=10.01.2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29634344
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28640434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277084
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603384
}}
}}
* {{medline-title
* {{medline-title
|title=Hyper-Expression of PD-1 Is Associated with the Levels of Exhausted and Dysfunctional Phenotypes of Circulating CD161 TCR iVα7.2  Mucosal-Associated Invariant T Cells in Chronic Hepatitis B Virus Infection.
|title=[Melatonin as a molecular marker of age-related pathologies].
|date=2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29616020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28557392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868455
 
}}
}}
* {{medline-title
* {{medline-title
|title=The Pharmacology of [[CD38]]/NADase: An Emerging Target in Cancer and Diseases of Aging.
|title=Chloroplast overexpression of rice caffeic acid O-methyltransferase increases melatonin production in chloroplasts via the 5-methoxytryptamine pathway in transgenic rice plants.
|date=04.2018
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482842
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28378373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885288
|full-text-url=https://sci-hub.do/10.1111/jpi.12412
}}
}}
* {{medline-title
* {{medline-title
|title=NAD  Deficiency Is a Common Central Pathological Factor of a Number of Diseases and Aging: Mechanisms and Therapeutic Implications.
|title=Age-dependent role of pre- and perinatal factors in interaction with genes on ADHD symptoms across adolescence.
|date=20.02.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29295624
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28259004
|full-text-url=https://sci-hub.do/10.1089/ars.2017.7445
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2017.02.014
}}
}}
* {{medline-title
* {{medline-title
|title=Reevaluation of immune activation in the era of cART and an aging HIV-infected population.
|title=Age differences in arterial and venous extra-cerebral blood flow in healthy adults: contributions of vascular risk factors and genetic variants.
|date=19.10.2017
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29046481
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28120105
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846952
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548544
}}
}}
* {{medline-title
* {{medline-title
|title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses.
|title=Executive function performance and change in aging is predicted by apolipoprotein E, intensified by catechol-O-methyltransferase and brain-derived neurotrophic factor, and moderated by age and lifestyle.
|date=17.08.2017
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28131014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359032
}}
}}
==IL6==
* {{medline-title
* {{medline-title
|title=Basic immunology may lead to translational therapeutic rationale: SARS-CoV-2 and rheumatic diseases.
|title=Age-Dependent Effects of Catechol-O-Methyltransferase ([[COMT]]) Gene Val158Met Polymorphism on Language Function in Developing Children.
|date=09.2020
|date=01.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32645207
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27909011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044402
}}
}}
* {{medline-title
* {{medline-title
|title=ATM-deficient neural precursors develop senescence phenotype with disturbances in autophagy.
|title=Aging and the genetic road towards the positivity effect in memory.
|date=09.2020
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32621937
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27350108
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111296
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.06.011
}}
}}
* {{medline-title
* {{medline-title
|title=The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification.
|title=Older age may offset genetic influence on affect: The [[COMT]] polymorphism and affective well-being across the life span.
|date=23.06.2020
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32585876
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27111524
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352675
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850911
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of Influenza on Pneumococcal Vaccine Effectiveness during [i]Streptococcus pneumoniae[/i] Infection in Aged Murine Lung.
|title=Differential effect of age on posterior and anterior hippocampal functional connectivity.
|date=11.06.2020
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32545261
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27034025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349919
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889536
}}
}}
* {{medline-title
* {{medline-title
|title=Patterns of multi-domain cognitive aging in participants of the Long Life Family Study.
|title=Pulse Pressure Magnifies the Effect of [[COMT]] Val(158)Met on 15 Years Episodic Memory Trajectories.
|date=10.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32514870
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26973509
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773588
}}
}}
* {{medline-title
* {{medline-title
|title=Cholest-4,6-Dien-3-One Promote Epithelial-To-Mesenchymal Transition (EMT) in Biliary Tree Stem/Progenitor Cell Cultures In Vitro.
|title=Modulative effects of [[COMT]] haplotype on age-related associations with brain morphology.
|date=15.11.2019
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31731674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26920810
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867428
}}
}}
* {{medline-title
* {{medline-title
|title=Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival.
|title=[[COMT]] Val158Met polymorphism is associated with blood pressure and lipid levels in general families of Bama longevous area in China.
|date=12.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31389140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26823844
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713630
}}
}}
* {{medline-title
* {{medline-title
|title=Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice.
|title=Genetic Basis of the Relationship Between Reproduction and Longevity: A Study on Common Variants of Three Genes in Steroid Hormone Metabolism--CYP17, [[HSD17B1]], and [[COMT]].
|date=25.06.2019
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31239406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25936248
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629005
|full-text-url=https://sci-hub.do/10.1089/rej.2015.1665
}}
}}
* {{medline-title
* {{medline-title
|title=N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms.
|title=Cognitive ability, intraindividual variability, and common genetic variants of catechol-O-methyltransferase and brain-derived neurotrophic factor: a longitudinal study in a population-based sample of older adults.
|date=05.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30951973
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24956006
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2019.02.012
|full-text-url=https://sci-hub.do/10.1037/a0035702
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent hepatic alterations induced by a high-fat high-fructose diet.
|title=Healthy aging increases the cognitive effects of two genes that influence extracellular dopamine.
|date=05.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30874869
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24956005
|full-text-url=https://sci-hub.do/10.1007/s00011-019-01223-1
|full-text-url=https://sci-hub.do/10.1037/a0036109
}}
}}
* {{medline-title
* {{medline-title
|title=Protective effects of a novel facial cream against environmental pollution: in vivo and in vitro assessment.
|title=[[BDNF]] and [[COMT]] polymorphisms have a limited association with episodic memory performance or engagement in complex cognitive activity in healthy older adults.
|date=2018
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30519068
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24468545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237134
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2014.01.013
}}
}}
==LRRK2==
* {{medline-title
* {{medline-title
|title=Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens.
|title=Accelerated telomere shortening independent of [[LRRK2]] variants in Chinese patients with Parkinson's disease.
|date=11.2018
|date=29.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269026
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33122450
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.09.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655166
}}
* {{medline-title
|title=Torquetenovirus (TTV) load is associated with mortality in Italian elderly subjects.
|date=02.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30223047
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.09.003
}}
}}
* {{medline-title
* {{medline-title
|title=Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity.
|title=The effect of [[LRRK2]] loss-of-function variants in humans.
|date=10.2018
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32461697
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303015
}}
}}
* {{medline-title
* {{medline-title
|title=Composition and richness of the serum microbiome differ by age and link to systemic inflammation.
|title=Parkinson's disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging.
|date=06.2018
|date=19.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29869736
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32075681
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031993
}}
}}
* {{medline-title
* {{medline-title
|title=Interleukin 6 Knockout Inhibits Aging-Related Accumulation of p53 in the Mouse Myocardium.
|title=Autophagy and [[LRRK2]] in the Aging Brain.
|date=16.01.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920513
|full-text-url=https://sci-hub.do/10.1093/gerona/gly105
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928047
}}
}}
* {{medline-title
* {{medline-title
|title=Age Dependent Hypothalamic and Pituitary Responses to Novel Environment Stress or Lipopolysaccharide in Rats.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=2018
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615881
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
* {{medline-title
* {{medline-title
|title=Sulodexide Slows Down the Senescence of Aortic Endothelial Cells Exposed to Serum from Patients with Peripheral Artery Diseases.
|title=Age-dependent accumulation of oligomeric [[SNCA]]/α-synuclein from impaired degradation in mutant [[LRRK2]] knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
|date=2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983487
|full-text-url=https://sci-hub.do/10.1159/000488167
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984454
}}
}}
* {{medline-title
* {{medline-title
|title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway.
|title=A Neuron-Glial Trans-Signaling Cascade Mediates [[LRRK2]]-Induced Neurodegeneration.
|date=03.2018
|date=12.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30759389
|full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474846
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence promotes in vivo reprogramming through p16  and IL-6.
|title=Upregulation of the p53-p21 pathway by G2019S [[LRRK2]] contributes to the cellular senescence and accumulation of α-synuclein.
|date=04.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280266
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712480
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847859
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422450
}}
}}
* {{medline-title
* {{medline-title
|title=Predictive value of multiple cytokines and chemokines for mortality in an admixed population: 15-year follow-up of the Bambui-Epigen (Brazil) cohort study of aging.
|title=G2019S [[LRRK2]] mutation facilitates α-synuclein neuropathology in aged mice.
|date=11.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803133
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30172844
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.002
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2018.08.018
}}
}}
* {{medline-title
* {{medline-title
|title=Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice.
|title=The Enzymatic Core of the Parkinson's Disease-Associated Protein [[LRRK2]] Impairs Mitochondrial Biogenesis in Aging Yeast.
|date=08.08.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28789683
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29977190
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021522
}}
}}
==PCNA==
* {{medline-title
* {{medline-title
|title=Impairment of Pol β-related DNA Base-excision Repair Leads to Ovarian Aging in Mice.
|title=Age-related pathology after adenoviral overexpression of the leucine-rich repeat kinase 2 in the mouse striatum.
|date=20.11.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33223510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29550548
|full-text-url=https://sci-hub.do/10.18632/aging.104123
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.02.008
}}
}}
* {{medline-title
* {{medline-title
|title=[Heat shock protein 90 (HSP90) in age-dependent changes in the number of fibroblasts in human skin.]
|title=[[LRRK2]] G2019S Induces Anxiety/Depression-like Behavior before the Onset of Motor Dysfunction with 5-HT  Receptor Upregulation in Mice.
|date=2020
|date=14.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32362082
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29305532
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705874
}}
}}
* {{medline-title
* {{medline-title
|title=A Higher Frequency Administration of the Nontoxic Cycloartane-Type Triterpene Argentatin A Improved Its Anti-Tumor Activity.
|title=Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.
|date=14.04.2020
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32295227
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29056298
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221627
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693787
}}
}}
* {{medline-title
* {{medline-title
|title=[Mechanosensitive protein of Hippo regulatory pathway - transcription coactivator with PZD-binding motif (TAZ) in human skin during aging.]
|title=Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in [[LRRK2]] G2019S knock-in mice.
|date=2019
|date=20.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32145162
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28930069
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633343
}}
}}
* {{medline-title
* {{medline-title
|title=[Mechanosensitive Yes-associated protein in human skin during aging.]
|title=Suppression of neuroinflammation by matrix metalloproteinase-8 inhibitor in aged normal and [[LRRK2]] G2019S Parkinson's disease model mice challenged with lipopolysaccharide.
|date=2019
|date=18.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31800177
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28958936
 
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.129
}}
}}
* {{medline-title
* {{medline-title
|title=[Role of mechanosensitive protein Piezo1 in human age-dependent changes in the number of fibroblasts and blood vessels in human skin.]
|title=Progression of pathology in [[PINK1]]-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.
|date=2019
|date=02.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31512421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28768533
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541666
}}
}}
* {{medline-title
* {{medline-title
|title=Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells.
|title=Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S [[LRRK2]] mice.
|date=11.2019
|date=14.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250567
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28292328
|full-text-url=https://sci-hub.do/10.1111/andr.12665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351259
}}
}}
* {{medline-title
* {{medline-title
|title=Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice.
|title=Combined [[LRRK2]] mutation, aging and chronic low dose oral rotenone as a model of Parkinson's disease.
|date=25.06.2019
|date=18.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31239406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28098219
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241661
}}
}}
* {{medline-title
* {{medline-title
|title=[Transforming growth factor-β (TGF-β) in human skin in the process of aging.]
|title=[[LRRK2]] BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function.
|date=2019
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31228363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26744332
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754049
}}
}}
* {{medline-title
* {{medline-title
|title=Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients.
|title=Functional and Morphological Correlates in the Drosophila [[LRRK2]] loss-of-function Model of Parkinson's Disease: Drug Effects of Withania somnifera (Dunal) Administration.
|date=06.06.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31130513
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26727265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608595
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699764
}}
}}
* {{medline-title
* {{medline-title
|title=High maternal milk intake in the postnatal life reduces the incidence of breast cancer during adulthood in rats.
|title=G2019S [[LRRK2]] and aging confer susceptibility to proteasome inhibitor-induced neurotoxicity in nigrostriatal dopaminergic system.
|date=08.2019
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30626462
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26253900
|full-text-url=https://sci-hub.do/10.1017/S2040174418001071
|full-text-url=https://sci-hub.do/10.1007/s00702-015-1438-9
}}
}}
* {{medline-title
* {{medline-title
|title=Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice.
|title=An early axonopathy in a h[[LRRK2]](R1441G) transgenic model of Parkinson disease.
|date=15.04.2019
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576894
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26192625
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.12.034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640977
}}
}}
* {{medline-title
* {{medline-title
|title=Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
|title=Mutations in [[LRRK2]] potentiate age-related impairment of autophagic flux.
|date=2018
|date=11.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26159606
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702340
}}
}}
* {{medline-title
* {{medline-title
|title=Genome Instability Is Promoted by the Chromatin-Binding Protein Spn1 in [i]Saccharomyces cerevisiae[/i].
|title=[11C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat.
|date=12.2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30301740
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25833342
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283154
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528008
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|title=Changes in actin dynamics and F-actin structure both in synaptoneurosomes of [[LRRK2]](R1441G) mutant mice and in primary human fibroblasts of [[LRRK2]](G2019S) mutation carriers.
|date=12.2018
|date=22.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25301747
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2014.09.070
}}
}}
* {{medline-title
* {{medline-title
|title=Conditioned medium from stimulated macrophages inhibits growth but induces an inflammatory phenotype in breast cancer cells.
|title=Genetic and pharmacological evidence that G2019S [[LRRK2]] confers a hyperkinetic phenotype, resistant to motor decline associated with aging.
|date=10.2018
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25107341
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.06.126
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194318
}}
}}
==MDM2==
* {{medline-title
* {{medline-title
|title=[Thyroid hormone receptors in human skin during aging.]
|title=SENEBLOC, a long non-coding RNA suppresses senescence via p53-dependent and independent mechanisms.
|date=2018
|date=06.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860734
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32030426
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102969
}}
}}
* {{medline-title
* {{medline-title
|title=Xanthohumol exerts protective effects in liver alterations associated with aging.
|title=Disruption of Robo2-Baiap2 integrated signaling drives cystic disease.
|date=03.2019
|date=19.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29536163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31534052
|full-text-url=https://sci-hub.do/10.1007/s00394-018-1657-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795383
}}
}}
* {{medline-title
* {{medline-title
|title=Comparison of naturally aging and D-galactose induced aging model in beagle dogs.
|title=Senescence-induced immunophenotype, gene expression and electrophysiology changes in human amniocytes.
|date=12.2017
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29285136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31478614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815807
}}
}}
* {{medline-title
* {{medline-title
|title=An Extract from the Plant [i]Deschampsia antarctica[/i] Protects Fibroblasts from Senescence Induced by Hydrogen Peroxide.
|title=Hsp90β interacts with [[MDM2]] to suppress p53-dependent senescence during skeletal muscle regeneration.
|date=2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31313490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718578
}}
}}
* {{medline-title
* {{medline-title
|title=[Age-related changes in the expression of lamin B receptors in fibroblasts of human dermis].
|title=TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway.
|date=2017
|date=07.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849880
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30845965
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404308
}}
}}
* {{medline-title
* {{medline-title
|title=Morphological alterations in the jejunal mucosa of aged rats and the possible protective role of green tea.
|title=Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells.
|date=2017
|date=28.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28813122
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30647108
|full-text-url=https://sci-hub.do/10.5603/FHC.a2017.0012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367206
}}
}}
==CD68==
* {{medline-title
* {{medline-title
|title=Insulin activates microglia and increases COX-2/IL-1β expression in young but not in aged hippocampus.
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|date=15.08.2020
|date=19.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32422127
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2020.146884
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic modulation of macrophage polarization prevents lumbar disc degeneration.
|title=The Dysfunctional [[MDM2]]-p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy.
|date=20.04.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32310825
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202517
|full-text-url=https://sci-hub.do/10.2337/db18-0684
}}
}}
* {{medline-title
* {{medline-title
|title=Cellular senescence in recurrent tonsillitis and tonsillar hypertrophy in children.
|title=Effect of [[CCNB1]] silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer.
|date=06.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32200310
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30069972
|full-text-url=https://sci-hub.do/10.1016/j.ijporl.2020.110004
|full-text-url=https://sci-hub.do/10.1002/jcp.26816
}}
}}
* {{medline-title
* {{medline-title
|title=Ginsenoside Rg1 supplementation clears senescence-associated β-galactosidase in exercising human skeletal muscle.
|title=Boosting [[ATM]] activity alleviates aging and extends lifespan in a mouse model of progeria.
|date=10.2019
|date=02.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31695564
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717979
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823780
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957528
}}
* {{medline-title
|title=Histopathological, immunohistochemical, and molecular studies for determination of wound age and vitality in rats.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31448552
|full-text-url=https://sci-hub.do/10.1111/iwj.13206
}}
}}
* {{medline-title
* {{medline-title
|title=Metabotropic glutamate receptor 5 ablation accelerates age-related neurodegeneration and neuroinflammation.
|title=Acute [[HSF1]] depletion induces cellular senescence through the [[MDM2]]-p53-p21 pathway in human diploid fibroblasts.
|date=06.2019
|date=08.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930274
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632240
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.020
|full-text-url=https://sci-hub.do/10.1242/jcs.210724
}}
}}
* {{medline-title
* {{medline-title
|title=Iba-1-/[[CD68]]+ microglia are a prominent feature of age-associated deep subcortical white matter lesions.
|title=Relevance of the p53-[[MDM2]] axis to aging.
|date=2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30682074
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29192902
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729541
}}
}}
* {{medline-title
* {{medline-title
|title=Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge.
|title=Pomegranate peel extract attenuates D-galactose-induced oxidative stress and hearing loss by regulating PNUTS/PP1 activity in the mouse cochlea.
|date=26.11.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30477578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28837860
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260864
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.07.007
}}
}}
* {{medline-title
* {{medline-title
|title=Partial reduction of microglia does not affect tau pathology in aged mice.
|title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway.
|date=09.11.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30413160
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro.
|title=Monitoring p53 by [[MDM2]] and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner.
|date=2018
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30408092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28118981
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328981
}}
}}
* {{medline-title
* {{medline-title
|title=Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
|title=Protection against High-Fat-Diet-Induced Obesity in [[MDM2]]  Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure.
|date=2018
|date=24.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28122227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560502
}}
}}
* {{medline-title
* {{medline-title
|title=Pathology and Distribution of Trombiculosis in Northern Chamois ( Rupicapra rupicapra rupicapra) in the Italian Alps.
|title=Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence.
|date=01.2019
|date=28.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30161018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28105936
|full-text-url=https://sci-hub.do/10.7589/2018-01-020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249001
}}
}}
* {{medline-title
* {{medline-title
|title=Stem Cell-Induced Pulp Regeneration Can Be Enhanced by Administration of [[CCL11]]-Neutralizing Antibody in the Ectopic Tooth Transplantation Model in the Aged Mice.
|title=Roles of [[TP53]] in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis.
|date=02.2019
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29962294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27776972
|full-text-url=https://sci-hub.do/10.1089/rej.2018.2064
|full-text-url=https://sci-hub.do/10.1016/j.jbior.2016.10.001
}}
}}
* {{medline-title
* {{medline-title
|title=Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain.
|title=Dynamics of ARF regulation that control senescence and cancer.
|date=06.2018
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27470213
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988593
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346319
}}
}}
* {{medline-title
* {{medline-title
|title=Chia Seed Supplementation Reduces Senescence Markers in Epididymal Adipose Tissue of High-Fat Diet-Fed SAMP8 Mice.
|title=Breaking a paradigm: IL-6/STAT3 signaling suppresses metastatic prostate cancer upon ARF expression.
|date=08.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29652550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27308625
|full-text-url=https://sci-hub.do/10.1089/jmf.2017.4129
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905394
}}
}}
* {{medline-title
* {{medline-title
|title=Lifelong environmental enrichment in the absence of exercise protects the brain from age-related cognitive decline.
|title=Combined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses.
|date=02.2019
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29630903
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26405565
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2018.03.042
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570092
}}
}}
* {{medline-title
* {{medline-title
|title=Age Dependent Hypothalamic and Pituitary Responses to Novel Environment Stress or Lipopolysaccharide in Rats.
|title=BI2536--A PLK inhibitor augments paclitaxel efficacy in suppressing tamoxifen induced senescence and resistance in breast cancer cells.
|date=2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615881
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26349973
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868128
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2015.07.005
}}
}}
* {{medline-title
* {{medline-title
|title=Secreted Klotho Attenuates Inflammation-Associated Aortic Valve Fibrosis in Senescence-Accelerated Mice P1.
|title=[[NQO1]] Stabilizes p53 in Response to Oncogene-Induced Senescence.
|date=05.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29581213
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26078718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466457
}}
}}
* {{medline-title
* {{medline-title
|title=Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of [[SIRT3]].
|title=[[MDM2]] turnover and expression of [[ATR]]X determine the choice between quiescence and senescence in response to [[CDK4]] inhibition.
|date=10.2018
|date=10.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29289557
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25803170
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.12.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480747
}}
}}
* {{medline-title
* {{medline-title
|title=The age-related slow increase in amyloid pathology in [[APP]].V717I mice activates microglia, but does not alter hippocampal neurogenesis.
|title=Senescence induction in renal carcinoma cells by Nutlin-3: a potential therapeutic strategy based on [[MDM2]] antagonism.
|date=01.2018
|date=28.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29059594
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25067787
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.09.013
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2014.07.024
}}
}}
* {{medline-title
* {{medline-title
|title=Morphological alterations in the jejunal mucosa of aged rats and the possible protective role of green tea.
|title=Germline genetics of the p53 pathway affect longevity in a gender specific manner.
|date=2017
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28813122
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24654968
|full-text-url=https://sci-hub.do/10.5603/FHC.a2017.0012
|full-text-url=https://sci-hub.do/10.2174/1874609807666140321150751
}}
}}
==FGF21==
==SIRT2==


* {{medline-title
* {{medline-title
|title=Differential effects of sulfur amino acid-restricted and low-calorie diets on gut microbiome profile and bile acid composition in male C57BL6/J mice.
|title=Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the [[SIRT2]]-dependent H4K16 deacetylation pathway.
|date=27.10.2020
|date=24.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33106871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31980591
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa270
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053624
}}
}}
* {{medline-title
* {{medline-title
|title=Relationship between physical activity and circulating fibroblast growth factor 21 in middle-aged and older adults.
|title=[[SIRT2]] functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.
|date=11.2020
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32911033
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31295472
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111081
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116639
}}
}}
* {{medline-title
* {{medline-title
|title=Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy.
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=09.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32863214
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365984
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
* {{medline-title
* {{medline-title
|title=Mitochondria, immunosenescence and inflammaging: a role for mitokines?
|title=Mitochondrial Stress-Initiated Aberrant Activation of the [[NLRP3]] Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging.
|date=10.2020
|date=22.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32757036
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673616
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371804
}}
}}
* {{medline-title
* {{medline-title
|title=Age-at-onset-dependent effects of sulfur amino acid restriction on markers of growth and stress in male F344 rats.
|title=Hsp90 Stabilizes [[SIRT1]] Orthologs in Mammalian Cells and [i]C. elegans[/i].
|date=07.2020
|date=20.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32573078
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426777
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930
}}
}}
* {{medline-title
* {{medline-title
|title=Fibroblast growth factor 21 prolongs lifespan and improves stress tolerance in the silkworm, [i]Bombyx mori[/i].
|title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes.
|date=03.2020
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32309367
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154471
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186
}}
}}
* {{medline-title
* {{medline-title
|title=Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice.
|title=High expression of CPT1b in skeletal muscle in metabolically healthy older subjects.
|date=13.11.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31723038
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657112
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aau4760
|full-text-url=https://sci-hub.do/10.1016/j.diabet.2018.01.018
}}
}}
* {{medline-title
* {{medline-title
|title=Fibroblast Growth Factor 21 Mediates the Associations between Exercise, Aging, and Glucose Regulation.
|title=Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans.
|date=02.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31490857
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249955
|full-text-url=https://sci-hub.do/10.1249/MSS.0000000000002150
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715387
}}
* {{medline-title
|title=Loss of [[SIRT2]] leads to axonal degeneration and locomotor disability associated with redox and energy imbalance.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28984064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676070
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Moderate Chronic Food Restriction on the Development of Postprandial Dyslipidemia with Ageing.
|title=[[SIRT2]] Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy.
|date=10.08.2019
|date=21.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31405194
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28947430
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723802
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698109
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of the Fission Machinery Mitigates [[OPA1]] Impairment in Adult Skeletal Muscles.
|title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa.
|date=15.06.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208084
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627087
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417
}}
}}
* {{medline-title
* {{medline-title
|title=Higher serum levels of fibroblast growth factor 21 in old patients with cachexia.
|title=Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders.
|date=07-08.2019
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30933730
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27882448
|full-text-url=https://sci-hub.do/10.1016/j.nut.2018.11.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357501
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of aging and caloric restriction on fibroblast growth factor 21 signaling in rat white adipose tissue.
|title=Resistance training and redox homeostasis: Correlation with age-associated genomic changes.
|date=04.2019
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30620889
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27687219
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040637
}}
}}
* {{medline-title
* {{medline-title
|title=Kotho and aging.
|title=Aging-related 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurochemial and behavioral deficits and redox dysfunction: improvement by AK-7.
|date=09.2016
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27235848
 
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.05.011
}}
}}
* {{medline-title
* {{medline-title
|title=The Klotho proteins in health and disease.
|title=Increased expression of [[SIRT2]] is a novel marker of cellular senescence and is dependent on wild type p53 status.
|date=01.2019
|date=17.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27229617
|full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968900
}}
}}
* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins.
|date=11.2018
|date=15.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27038700
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.015
}}
}}
* {{medline-title
* {{medline-title
|title=Aging is associated with increased [[FGF21]] levels but unaltered [[FGF21]] responsiveness in adipose tissue.
|title=Sirtuins, Cell Senescence, and Vascular Aging.
|date=10.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30043445
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26948035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156525
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848124
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
|title=The expression levels of the sirtuins in patients with BCC.
|date=12.2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26631040
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896
|full-text-url=https://sci-hub.do/10.1007/s13277-015-4522-8
}}
}}
* {{medline-title
* {{medline-title
|title=Human Aging and Longevity Are Characterized by High Levels of Mitokines.
|title=Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum.
|date=23.04.2019
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26556180
|full-text-url=https://sci-hub.do/10.1093/gerona/gly153
|full-text-url=https://sci-hub.do/10.1111/jsm.13035
}}
}}
* {{medline-title
* {{medline-title
|title=[Fibroblast growth factor-21 as a marker of premature aging in young and middled-aged men with type 2 diabetes].
|title=Localization of sirtuins ([[SIRT1]]-7) in the aged mouse inner ear.
|date=03.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29634140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26472659
 
|full-text-url=https://sci-hub.do/10.3109/00016489.2015.1093172
}}
}}
* {{medline-title
* {{medline-title
|title=Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through [[SIRT1]].
|title=Aging-related rotenone-induced neurochemical and behavioral deficits: role of [[SIRT2]] and redox imbalance, and neuroprotection by AK-7.
|date=2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29118911
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26089639
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666058
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466888
}}
}}
* {{medline-title
* {{medline-title
|title=Integrated stress response stimulates [[FGF21]] expression: Systemic enhancer of longevity.
|title=Differential expression of sirtuins in the aging rat brain.
|date=12.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28844867
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005404
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2017.08.009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424846
}}
}}
==IVD==
* {{medline-title
* {{medline-title
|title=MicroRNAs in Intervertebral Disc Degeneration, Apoptosis, Inflammation, and Mechanobiology.
|title=Polymorphisms Falling Within Putative miRNA Target Sites in the 3'UTR Region of [[SIRT2]] and [[DRD2]] Genes Are Correlated With Human Longevity.
|date=20.05.2020
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32443722
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25934993
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279351
|full-text-url=https://sci-hub.do/10.1093/gerona/glv058
}}
}}
* {{medline-title
* {{medline-title
|title=A step-by-step protocol for isolation of murine nucleus pulposus cells.
|title=The role of melatonin, sirtuin2 and FoXO1 transcription factor in the aging process of colon in male rats.
|date=12.2019
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31891122
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25430724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920701
|full-text-url=https://sci-hub.do/10.1007/s10522-014-9540-1
}}
}}
* {{medline-title
* {{medline-title
|title=Caspase-3 knockout inhibits intervertebral disc degeneration related to injury but accelerates degeneration related to aging.
|title=[[[SIRT2]], a multi-talented deacetylase].
|date=18.12.2019
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31852919
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24939540
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920379
|full-text-url=https://sci-hub.do/10.1051/medsci/20143005016
}}
}}
* {{medline-title
* {{medline-title
|title=Finite element and deformation analyses predict pattern of bone failure in loaded zebrafish spines.
|title=[[SIRT2]] induces the checkpoint kinase BubR1 to increase lifespan.
|date=29.11.2019
|date=01.07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31690186
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24825348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194088
}}
}}
==APC==
* {{medline-title
* {{medline-title
|title=Improvement in determining the risk of damage to the human lumbar functional spinal unit considering age, height, weight and sex using a combination of FEM and RSM.
|title=Differences between blacks and whites in well-being, beliefs, emotional states, behaviors and survival, 1978-2014.
|date=02.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31473842
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32925952
|full-text-url=https://sci-hub.do/10.1007/s10237-019-01215-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489510
}}
}}
* {{medline-title
* {{medline-title
|title=In vivo contrast-enhanced microCT for the monitoring of mouse thoracic, lumbar, and coccygeal intervertebral discs.
|title=Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging.
|date=06.2019
|date=07.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31463468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32771388
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686789
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672319
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway.
|title=Burden of musculoskeletal disorders in Iran during 1990-2017: estimates from the Global Burden of Disease Study 2017.
|date=15.04.2019
|date=10.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30987676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32651719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769
|full-text-url=https://sci-hub.do/10.1007/s11657-020-00767-8
}}
}}
* {{medline-title
* {{medline-title
|title=Curcumin and o-Vanillin Exhibit Evidence of Senolytic Activity in Human [[IVD]] Cells In Vitro.
|title=Fall-related mortality trends in older Japanese adults aged ≥65 years: a nationwide observational study.
|date=29.03.2019
|date=11.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30934902
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31831549
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924807
}}
}}
* {{medline-title
* {{medline-title
|title=Aging of mouse intervertebral disc and association with back pain.
|title=Stroke Mortality Rates and Trends in Romania, 1994-2017.
|date=06.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30936040
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31624036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549718
|full-text-url=https://sci-hub.do/10.1016/j.jstrokecerebrovasdis.2019.104431
}}
}}
* {{medline-title
* {{medline-title
|title=Role of heparan sulfate 6-0 endosulfatases in intervertebral disc homeostasis.
|title=A new approach to quantifying the EEG during walking: Initial evidence of gait related potentials and their changes with aging and dual tasking.
|date=09.2019
|date=15.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30924907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31449852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742574
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110709
}}
}}
* {{medline-title
* {{medline-title
|title=Evaluation of age-related changes in lumbar facet joints using T2 mapping.
|title=Risk-period-cohort approach for averting identification problems in longitudinal models.
|date=01.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31291339
|full-text-url=https://sci-hub.do/10.1016/j.jos.2019.02.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620014
}}
}}
* {{medline-title
* {{medline-title
|title=A histocytological and radiological overview of the natural history of intervertebral disk: from embryonic formation to age-related degeneration.
|title=Wnt Signaling Mediates the Aging-Induced Differentiation Impairment of Intestinal Stem Cells.
|date=04.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30715648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790135
|full-text-url=https://sci-hub.do/10.1007/s00586-019-05903-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534527
}}
}}
* {{medline-title
* {{medline-title
|title=Regenerative potential of human nucleus pulposus resident stem/progenitor cells declines with ageing and intervertebral disc degeneration.
|title=Biased estimation of trends in cohort effects: the problems with age-period-cohort models in ecology.
|date=10.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30015833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30347112
|full-text-url=https://sci-hub.do/10.3892/ijmm.2018.3766
|full-text-url=https://sci-hub.do/10.1002/ecy.2545
}}
}}
* {{medline-title
* {{medline-title
|title=[[TRPC6]] in simulated microgravity of intervertebral disc cells.
|title=[Gender Differences in Projected Life Expectancy in Japan (2023-2047) Determined by Bayesian Age-Period-Cohort Analysis].
|date=10.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29968164
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270302
|full-text-url=https://sci-hub.do/10.1007/s00586-018-5688-8
|full-text-url=https://sci-hub.do/10.1265/jjh.73.338
}}
}}
* {{medline-title
* {{medline-title
|title=FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration.
|title=Activated Yes-Associated Protein Accelerates Cell Cycle, Inhibits Apoptosis, and Delays Senescence in Human Periodontal Ligament Stem Cells.
|date=10.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963746
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30123063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097269
}}
}}
* {{medline-title
* {{medline-title
|title=Major traits of the senescent phenotype of nucleus pulposus intervertebral disc cells persist under the specific microenvironmental conditions of the tissue.
|title=Activating the Anaphase Promoting Complex to Enhance Genomic Stability and Prolong Lifespan.
|date=01.2019
|date=27.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29954095
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.05.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073722
}}
}}
* {{medline-title
* {{medline-title
|title=[Influence analysis of aging of spinal segment on the mechanical behavior of vertebral cortex].
|title=Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04.
|date=01.06.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29745502
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29675370
|full-text-url=https://sci-hub.do/10.7507/1001-5515.201608050
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902356
}}
}}
* {{medline-title
* {{medline-title
|title=The adolescent idiopathic scoliotic [[IVD]] displays advanced aggrecanolysis and a glycosaminoglycan composition similar to that of aged human and ovine [[IVD]]s.
|title=[Role and alterations of DNA methylation during the aging and cancer].
|date=09.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29441417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|full-text-url=https://sci-hub.do/10.1007/s00586-018-5515-2
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
}}
}}
* {{medline-title
* {{medline-title
|title=Costs and benefits of diagnostic testing: four ways to improve patient care by purposive use of in vitro diagnostics.
|title=MicroRNA-210-mediated proliferation, survival, and angiogenesis promote cardiac repair post myocardial infarction in rodents.
|date=2017
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29185242
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948298
|full-text-url=https://sci-hub.do/10.4414/smw.2017.14546
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941944
}}
}}
* {{medline-title
* {{medline-title
|title=Matrisome Profiling During Intervertebral Disc Development And Ageing.
|title=IL-6 Production by TLR-Activated [[APC]] Broadly Enhances Aged Cognate [[CD4]] Helper and B Cell Antibody Responses In Vivo.
|date=14.09.2017
|date=01.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912585
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28250157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360529
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related decline in [[AMH]] is assay dependent limiting clinical interpretation of repeat [[AMH]] measures across the reproductive lifespan.
|title=Standard expected years of life lost due to tuberculosis in Poland.
|date=02.2018
|date=01.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28792788
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28234085
|full-text-url=https://sci-hub.do/10.1080/09513590.2017.1358708
|full-text-url=https://sci-hub.do/10.5588/ijtld.16.0268
}}
}}
==LMNA==
* {{medline-title
* {{medline-title
|title=Metformin alters peripheral blood mononuclear cells (PBMC) senescence biomarkers gene expression in type 2 diabetic patients.
|title=The effects of New York City's coordinated public health programmes on mortality through 2011.
|date=01.2021
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33187870
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031310
|full-text-url=https://sci-hub.do/10.1016/j.jdiacomp.2020.107758
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251557
}}
}}
* {{medline-title
* {{medline-title
|title=Protein structural and mechanistic basis of progeroid laminopathies.
|title=Regional variation in coronary heart disease mortality trends in Portugal, 1981-2012.
|date=16.08.2020
|date=01.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32799420
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27665398
|full-text-url=https://sci-hub.do/10.1111/febs.15526
|full-text-url=https://sci-hub.do/10.1016/j.ijcard.2016.09.059
}}
}}
* {{medline-title
* {{medline-title
|title=Progerin Expression Induces Inflammation, Oxidative Stress and Senescence in Human Coronary Endothelial Cells.
|title=Mitotic degradation of yeast Fkh1 by the Anaphase Promoting Complex is required for normal longevity, genomic stability and stress resistance.
|date=12.05.2020
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32408587
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27099939
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290406
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925830
}}
}}
* {{medline-title
* {{medline-title
|title=The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes.
|title=Breast Cancer Trend in Iran from 2000 to 2009 and Prediction till 2020 using a Trend Analysis Method.
|date=04.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32196928
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27039796
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189991
|full-text-url=https://sci-hub.do/10.7314/apjcp.2016.17.3.1493
}}
}}
* {{medline-title
* {{medline-title
|title=Pharmacotherapy to gene editing: potential therapeutic approaches for Hutchinson-Gilford progeria syndrome.
|title=Secular trend analysis of lung cancer incidence in Sihui city, China between 1987 and 2011.
|date=04.2020
|date=31.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32048129
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26227634
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593355
}}
}}
* {{medline-title
* {{medline-title
|title=Long term breeding of the Lmna G609G progeric mouse: Characterization of homozygous and heterozygous models.
|title=Black-white disparity in disability among U.S. older adults: age, period, and cohort trends.
|date=02.2020
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794853
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24986183
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189652
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes.
|title=Conserved mechanisms of tumorigenesis in the Drosophila adult midgut.
|date=10.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24516653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916428
}}
}}
* {{medline-title
* {{medline-title
|title=Transient introduction of human telomerase mRNA improves hallmarks of progeria cells.
|title=[[CD4]] T cell defects in the aged: causes, consequences and strategies to circumvent.
|date=08.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31152494
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24440384
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612639
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989398
}}
}}
==CA2==
* {{medline-title
* {{medline-title
|title=A humanized yeast system to analyze cleavage of prelamin A by [[ZMPSTE24]].
|title=Maintaining Aging Hippocampal Function with Safe and Feasible Shaking Exercise in SAMP10 Mice.
|date=15.03.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30625386
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32526748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401292
|full-text-url=https://sci-hub.do/10.1159/000507884
}}
}}
* {{medline-title
* {{medline-title
|title=Impaired immune surveillance accelerates accumulation of senescent cells and aging.
|title=One-year Follow-up Study of Hippocampal Subfield Atrophy in Alzheimer's Disease and Normal Aging.
|date=21.12.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30575733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32008518
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303397
|full-text-url=https://sci-hub.do/10.2174/1573405615666190327102052
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse.
|title=Maturation of PNN and ErbB4 Signaling in Area [[CA2]] during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory.
|date=01.02.2019
|date=29.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30422822
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665627
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355303
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.09.044
}}
}}
* {{medline-title
* {{medline-title
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
|title=Early disruption of parvalbumin expression and perineuronal nets in the hippocampus of the Tg2576 mouse model of Alzheimer's disease can be rescued by enriched environment.
|date=12.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30273829
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.08.024
}}
}}
* {{medline-title
* {{medline-title
|title=Altered modulation of lamin A/C-[[HDAC2]] interaction and p21 expression during oxidative stress response in HGPS.
|title=Protracted hippocampal development is associated with age-related improvements in memory during early childhood.
|date=10.2018
|date=01.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30109767
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518573
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949262
}}
}}
* {{medline-title
* {{medline-title
|title=Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
|title=Neurodevelopment and behavior in neonatal OXYS rats with genetically determined accelerated senescence.
|date=09.2018
|date=15.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037605
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29274882
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2018.06.029
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2017.12.021
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic changes during adult stage in pre-optic, hypothalamus, hippocampus and pituitary regions of female rat brain following neonatal exposure to estradiol-17β.
|title=Effect of Chronic Administration of Resveratrol on Cognitive Performance during Aging Process in Rats.
|date=15.09.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29777688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163756
|full-text-url=https://sci-hub.do/10.1016/j.ygcen.2018.05.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661096
}}
}}
* {{medline-title
* {{medline-title
|title=RECQ helicase disease and related progeroid syndromes: RECQ2018 meeting.
|title=Time of day but not aging regulates 5-HT  receptor binding sites in the hamster hippocampus.
|date=07.2018
|date=01.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29752965
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29107707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217841
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.10.057
}}
}}
* {{medline-title
* {{medline-title
|title=Upregulation of the aging related [[LMNA]] splice variant progerin in dilated cardiomyopathy.
|title=Cytoarchitectonically-driven MRI atlas of nonhuman primate hippocampus: Preservation of subfield volumes in aging.
|date=2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29702688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29072793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922532
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920786
}}
}}
* {{medline-title
* {{medline-title
|title=Increasing autophagy and blocking Nrf2 suppress laminopathy-induced age-dependent cardiac dysfunction and shortened lifespan.
|title=Hippocampal sclerosis, hippocampal neuron loss patterns and TDP-43 in the aged population.
|date=06.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29575479
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28833898
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946079
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099461
}}
}}
* {{medline-title
* {{medline-title
|title=Lipodystrophic syndromes due to [[LMNA]] mutations: recent developments on biomolecular aspects, pathophysiological hypotheses and therapeutic perspectives.
|title=Aging Does Not Affect Axon Initial Segment Structure and Somatic Localization of Tau Protein in Hippocampal Neurons of Fischer 344 Rats.
|date=01.01.2018
|date=07-08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29578370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28785724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973242
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520750
}}
}}
* {{medline-title
* {{medline-title
|title=Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome.
|title=Dancing or Fitness Sport? The Effects of Two Training Programs on Hippocampal Plasticity and Balance Abilities in Healthy Seniors.
|date=04.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476423
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28674488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475381
}}
}}
* {{medline-title
* {{medline-title
|title=Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing.
|title=Comparison of the influence of two models of mild stress on hippocampal brain-derived neurotrophin factor ([[BDNF]]) immunoreactivity in old age rats.
|date=03.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29208544
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28379217
|full-text-url=https://sci-hub.do/10.1016/j.arr.2017.12.001
|full-text-url=https://sci-hub.do/10.21307/ane-2017-037
}}
}}
==SHBG==
* {{medline-title
* {{medline-title
|title=Endogenous Testosterone Levels and the Risk of Incident Cardiovascular Events in Elderly Men: The MrOS Prospective Study.
|title=Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis.
|date=01.05.2020
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32337470
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889579
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173399
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2016.11.007
}}
}}
* {{medline-title
* {{medline-title
|title=Associations of Endogenous Sex Hormones with Carotid Plaque Burden and Characteristics in Midlife Women.
|title=Depressive symptoms modify age effects on hippocampal subfields in older adults.
|date=01.04.2020
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31900485
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27696657
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376518
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of the Relationship between the Levels of Androgens and Biochemical Bone Markers in Men Aged 60-75 Years.
|title=Roles of hippocampal subfields in verbal and visual episodic memory.
|date=22.12.2019
|date=15.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31877849
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27646772
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982106
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343125
}}
}}
* {{medline-title
* {{medline-title
|title=Testosterone and Estrone Increase From the Age of 70 Years: Findings From the Sex Hormones in Older Women Study.
|title=Age-Dependent Specific Changes in Area [[CA2]] of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome.
|date=01.12.2019
|date=06.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31408149
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26748091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830527
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706988
}}
}}
* {{medline-title
* {{medline-title
|title=Aging and the Male Reproductive System.
|title=Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet.
|date=01.08.2019
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888401
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26444078
|full-text-url=https://sci-hub.do/10.1210/er.2018-00178
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2015.09.010
}}
}}
* {{medline-title
* {{medline-title
|title=Prospective associations of androgens and sex hormone-binding globulin with 12-month, lifetime and incident anxiety and depressive disorders in men and women from the general population.
|title=Hippocampal cytogenesis and spatial learning in senile rats exposed to chronic variable stress: effects of previous early life exposure to mild stress.
|date=15.02.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30699875
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26347648
|full-text-url=https://sci-hub.do/10.1016/j.jad.2018.11.052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539520
}}
}}
* {{medline-title
* {{medline-title
|title=Cross-sectional associations of sex hormones with leucocyte telomere length, a marker of biological age, in a community-based cohort of older men.
|title=Longitudinal reproducibility of automatically segmented hippocampal subfields: A multisite European 3T study on healthy elderly.
|date=04.2019
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30561819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26043939
|full-text-url=https://sci-hub.do/10.1111/cen.13918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869769
}}
}}
* {{medline-title
* {{medline-title
|title=Testosterone level in aging male with different glucose tolerance state and its association with osteocalcin.
|title=Fluid percussion injury device for the precise control of injury parameters.
|date=03.2019
|date=15.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30039993
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25800515
|full-text-url=https://sci-hub.do/10.1080/13685538.2018.1481940
|full-text-url=https://sci-hub.do/10.1016/j.jneumeth.2015.03.010
}}
}}
* {{medline-title
* {{medline-title
|title=Inverse association of testosterone and sex hormone binding globulin levels with leukocyte count in middle-aged and elderly men.
|title=Characterization of Periodic Acid-Schiff-Positive Granular Deposits in the Hippocampus of SJL/J Mice.
|date=09.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29863448
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25694088
|full-text-url=https://sci-hub.do/10.1080/13685538.2018.1477934
|full-text-url=https://sci-hub.do/10.1177/0192623314564254
}}
}}
* {{medline-title
* {{medline-title
|title=[Vasectomy has no obvious longterm influence on the levels of serum androgens in aging males].
|title=Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings.
|date=02.2017
|date=30.12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29658249
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25266915
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254356
}}
}}
* {{medline-title
* {{medline-title
|title=GONADOPENIA AND AGING IN MEN.
|title=Hippocampal subfield volumes at 7T in early Alzheimer's disease and normal aging.
|date=04.2018
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29658833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24684788
|full-text-url=https://sci-hub.do/10.4158/EP-2017-0131
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2014.02.021
}}
}}
* {{medline-title
* {{medline-title
|title=Reassessing Free-Testosterone Calculation by Liquid Chromatography-Tandem Mass Spectrometry Direct Equilibrium Dialysis.
|title=Moringa oleifera mitigates memory impairment and neurodegeneration in animal model of age-related dementia.
|date=01.06.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29618085
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24454988
|full-text-url=https://sci-hub.do/10.1210/jc.2017-02360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884855
}}
}}
==TLR2==
* {{medline-title
* {{medline-title
|title=Plasma steroids, body composition, and fat distribution: effects of age, sex, and exercise training.
|title=Changes in salivary microbial sensing proteins CD14 and [[TLR2]] with aging.
|date=07.2018
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29507393
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32529494
|full-text-url=https://sci-hub.do/10.1038/s41366-018-0033-1
|full-text-url=https://sci-hub.do/10.1007/s00784-020-03274-9
}}
}}
* {{medline-title
* {{medline-title
|title=New determinants for gallstone disease?
.
|title=Culture Model for Non-human Primate Choroid Plexus.
|date=02.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29393043
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31555096
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724611
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of acute and chronic exercise on steroid hormone fluctuations in young and middle-aged men.
|title=Changes in fetal membrane histology with cervical insufficiency and transabdominal cerclage.
|date=04.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29378227
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31004354
|full-text-url=https://sci-hub.do/10.1016/j.steroids.2018.01.011
|full-text-url=https://sci-hub.do/10.1002/ijgo.12826
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of growth hormone administration on luteinizing hormone secretion in healthy older men and women.
|title=Aging leads to dysfunctional innate immune responses to [[TLR2]] and [[TLR4]] agonists.
|date=12.2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29208686
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30402800
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504629
}}
}}
* {{medline-title
* {{medline-title
|title=Individual testosterone decline and future mortality risk in men.
|title=The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease.
|date=01.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066571
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30271656
|full-text-url=https://sci-hub.do/10.1530/EJE-17-0280
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147589
}}
}}
* {{medline-title
* {{medline-title
|title=Ageratum conyzoides L. inhibits 5-alpha-reductase gene expression in human prostate cells and reduces symptoms of benign prostatic hypertrophy in otherwise healthy men in a double blind randomized placebo controlled clinical study.
|title=Aging modulates microglia phenotypes in neuroinflammation of MPTP-PD mice.
|date=11.2017
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29048765
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30009921
|full-text-url=https://sci-hub.do/10.1002/biof.1389
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.010
}}
}}
* {{medline-title
* {{medline-title
|title=Evaluating Calculated Free Testosterone as a Predictor of Morbidity and Mortality Independent of Testosterone for Cross-sectional and 5-Year Longitudinal Health Outcomes in Older Men: The Concord Health and Ageing in Men Project.
|title=Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice.
|date=09.05.2018
|date=24.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28958048
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29929978
|full-text-url=https://sci-hub.do/10.1093/gerona/glx170
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109936
}}
}}
* {{medline-title
* {{medline-title
|title=Progressive impairment of testicular endocrine function in ageing men: Testosterone and dihydrotestosterone decrease, and luteinizing hormone increases, in men transitioning from the 8th to 9th decades of life.
|title=Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging.
|date=01.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28945276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624852
|full-text-url=https://sci-hub.do/10.1111/cen.13484
|full-text-url=https://sci-hub.do/10.1002/cyto.a.23372
}}
}}
* {{medline-title
* {{medline-title
|title=The impact of age, BMI and sex hormone on aging males' symptoms and the international index of erectile function scores.
|title=[[TLR4]] and [[TLR2]] activation is differentially associated with age during Parkinson's disease.
|date=12.2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28780904
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29077524
|full-text-url=https://sci-hub.do/10.1080/13685538.2017.1361399
|full-text-url=https://sci-hub.do/10.1080/08820139.2017.1379024
}}
}}
==TP53==
* {{medline-title
* {{medline-title
|title=p53 inhibits the osteogenic differentiation but does not induce senescence in human dental follicle cells.
|title=Role of pattern recognition receptors of the neurovascular unit in inflamm-aging.
|date=07-08.2020
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32473528
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28801521
|full-text-url=https://sci-hub.do/10.1016/j.diff.2020.05.003
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00106.2017
}}
}}
* {{medline-title
* {{medline-title
|title=Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals.
|title=Ionizing radiation reduces [[ADAM10]] expression in brain microvascular endothelial cells undergoing stress-induced senescence.
|date=02.04.2020
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32243522
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28437250
|full-text-url=https://sci-hub.do/10.1182/blood.2019004362
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425125
}}
}}
* {{medline-title
* {{medline-title
|title=[[TP53]]/miR-34a-associated signaling targets [i]SERPINE1[/i] expression in human pancreatic cancer.
|title=Aging-related Atg5 defect impairs neutrophil extracellular traps formation.
|date=27.01.2020
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31986125
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28375544
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506403
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of p16 in nodular fasciitis: an implication for self-limited and inflammatory nature of the lesion.
|title=Chronoinflammaging in Alzheimer; A systematic review on the roles of toll like receptor 2.
|date=2019
|date=15.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31933915
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28087373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945175
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.01.003
}}
}}
* {{medline-title
* {{medline-title
|title=Ultra-Sensitive [[TP53]] Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan.
|title=Aged B cells alter immune regulation of allografts in mice.
|date=02.07.2019
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31269435
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27546296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639023
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366259
}}
}}
* {{medline-title
* {{medline-title
|title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity.
|title=Estrogen receptors alpha mediates postischemic inflammation in chronically estrogen-deprived mice.
|date=10.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26973103
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.01.002
}}
}}
* {{medline-title
* {{medline-title
|title=mTOR Signaling Pathway Regulates Sperm Quality in Older Men.
|title=Effects of aerobic training on markers of autophagy in the elderly.
|date=21.06.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31234465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26940016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627782
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005904
}}
}}
* {{medline-title
* {{medline-title
|title=[i][[TP53]][/i] Tumor-suppressor Gene Plays a Key Role in [[IGF1]] Signaling Pathway Related to the Aging of Human Melanocytes.
|title=Reduced levels of cytosolic DNA sensor [[AIM2]] are associated with impaired cytokine responses in healthy elderly.
|date=05.2019
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092438
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26944367
|full-text-url=https://sci-hub.do/10.21873/anticanres.13363
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.02.016
}}
}}
* {{medline-title
* {{medline-title
|title=Distinct cellular responses to replication stress leading to apoptosis or senescence.
|title=Immune ageing and susceptibility to Streptococcus pneumoniae.
|date=05.2019
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30982228
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26472172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487726
|full-text-url=https://sci-hub.do/10.1007/s10522-015-9614-8
}}
}}
* {{medline-title
* {{medline-title
|title=Somatic genome alterations in relation to age in lung adenocarcinoma.
|title=Monocyte Phenotype and Polyfunctionality Are Associated With Elevated Soluble Inflammatory Markers, Cytomegalovirus Infection, and Functional and Cognitive Decline in Elderly Adults.
|date=15.10.2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30859574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26286603
|full-text-url=https://sci-hub.do/10.1002/ijc.32265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007736
}}
}}
* {{medline-title
* {{medline-title
|title=Predictors of disease aggressiveness influence outcome from immunotherapy treatment in renal clear cell carcinoma.
|title=Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice.
|date=2019
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30546942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287778
|full-text-url=https://sci-hub.do/10.1016/j.patbio.2015.03.002
}}
}}
* {{medline-title
* {{medline-title
|title=Adipose [[TSHB]] in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence.
|title=Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal [[TLR4]] activation in aged rats.
|date=2018
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448824
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25839444
|full-text-url=https://sci-hub.do/10.1159/000495170
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2015.02.008
}}
}}
* {{medline-title
* {{medline-title
|title=Breast cancer survival predicted by [[TP53]] mutation status differs markedly depending on treatment.
|title=Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture.
|date=01.10.2018
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30285883
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25797136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167800
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.03.009
}}
}}
* {{medline-title
* {{medline-title
|title=Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis.
|title=Aging does not affect the ability of human monocyte-derived dendritic cells to phagocytose Candida albicans.
|date=2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025494
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25783173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152523
|full-text-url=https://sci-hub.do/10.1007/s40520-015-0344-1
}}
}}
* {{medline-title
* {{medline-title
|title=Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of [[TP53]].
|title=Cardiac autonomic dysfunction: particulate air pollution effects are modulated by epigenetic immunoregulation of Toll-like receptor 2 and dietary flavonoid intake.
|date=11.2018
|date=27.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25628407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106910
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330067
}}
}}
* {{medline-title
* {{medline-title
|title=Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo.
|title=Bacteria and Toll-like receptor and cytokine mRNA expression profiles associated with canine arthritis.
|date=08.2018
|date=15.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29923368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24856731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052487
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2014.04.004
}}
}}
==AFM==
* {{medline-title
* {{medline-title
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.
|title=Photocatalytic aging process of Nano-TiO  coated polypropylene microplastics: Combining atomic force microscopy and infrared spectroscopy ([[AFM]]-IR) for nanoscale chemical characterization.
|date=15.07.2018
|date=15.02.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33080556
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179
|full-text-url=https://sci-hub.do/10.1016/j.jhazmat.2020.124159
}}
}}
* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=Nanoscale infrared, thermal and mechanical properties of aged microplastics revealed by an atomic force microscopy coupled with infrared spectroscopy ([[AFM]]-IR) technique.
|date=06.2018
|date=20.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32702545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2020.140944
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of human age-associated gene co-expressions in functional modules using liquid association.
|title=Detecting zeta potential of polydimethylsiloxane (PDMS) in electrolyte solutions with atomic force microscope.
|date=02.01.2018
|date=15.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416677
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32521351
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787419
|full-text-url=https://sci-hub.do/10.1016/j.jcis.2020.05.061
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic interrogation of replicative senescence uncovers a dual role for [[USP28]] in coordinating the p53 and [[GATA4]] branches of the senescence program.
|title=Recent Applications of Advanced Atomic Force Microscopy in Polymer Science: A Review.
|date=01.10.2017
|date=17.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32429499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284686
}}
}}
* {{medline-title
* {{medline-title
|title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
|title=Active fractions of mannoproteins derived from yeast cell wall stimulate innate and acquired immunity of adult and elderly dogs.
|date=10.08.2017
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32288071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126846
}}
}}
==ATR==
* {{medline-title
* {{medline-title
|title=Bloodstain age estimation through infrared spectroscopy and Chemometric models.
|title=The Effect of Waste Engine Oil and Waste Polyethylene on UV Aging Resistance of Asphalt.
|date=11.2020
|date=06.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33077037
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32155867
|full-text-url=https://sci-hub.do/10.1016/j.scijus.2020.07.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182932
}}
}}
* {{medline-title
* {{medline-title
|title=Artificial Intelligence and fourier-transform infrared spectroscopy for evaluating water-mediated degradation of lubricant oils.
|title=Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans.
|date=01.11.2020
|date=25.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32887052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32098962
|full-text-url=https://sci-hub.do/10.1016/j.talanta.2020.121312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042263
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence Induction by Combined Ionizing Radiation and DNA Damage Response Inhibitors in Head and Neck Squamous Cell Carcinoma Cells.
|title=Nanomechanical insights: Amyloid beta oligomer-induced senescent brain endothelial cells.
|date=01.09.2020
|date=01.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32883016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31513781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563880
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791778
}}
}}
* {{medline-title
* {{medline-title
|title=Kinetics of thermal degradation and lifetime study of poly(vinylidene fluoride) (PVDF) subjected to bioethanol fuel accelerated aging.
|title=Application of atomic force microscopy in the analysis of time since deposition (TSD) of red blood cells in bloodstains: A forensic analysis.
|date=07.2020
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32775731
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31181409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398943
|full-text-url=https://sci-hub.do/10.1016/j.forsciint.2019.05.048
}}
}}
* {{medline-title
* {{medline-title
|title=Supraphysiological protection from replication stress does not extend mammalian lifespan.
|title=Iceland spar calcite: Humidity and time effects on surface properties and their reversibility.
|date=06.04.2020
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32253367
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30682592
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185120
|full-text-url=https://sci-hub.do/10.1016/j.jcis.2019.01.047
}}
}}
* {{medline-title
* {{medline-title
|title=Assessing the Retest Reliability of Prefrontal EEG Markers of Brain Rhythm Slowing in the Eyes-Closed Resting State.
|title=Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column.
|date=09.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32253926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29747057
|full-text-url=https://sci-hub.do/10.1177/1550059420914832
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2018.05.004
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Hydrogen Peroxide and Sodium Hypochlorite Aging on Properties and Performance of Polyethersulfone Ultrafiltration Membrane.
|title=Multiscale Poroviscoelastic Compressive Properties of Mouse Supraspinatus Tendons Are Altered in Young and Aged Mice.
|date=18.10.2019
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31635217
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29238818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816244
}}
}}
* {{medline-title
* {{medline-title
|title=NF-κB signaling in skin aging.
|title=Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease.
|date=12.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28812215
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111160
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665708
}}
}}
* {{medline-title
* {{medline-title
|title=Development of a w/o emulsion using ionic liquid strategy for transdermal delivery of anti - aging component α - lipoic acid: Mechanism of different ionic liquids on skin retention and efficacy evaluation.
|title=Effect of intra-oral aging on t→m phase transformation, microstructure, and mechanical properties of Y-TZP dental ceramics.
|date=01.01.2020
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634554
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28432999
|full-text-url=https://sci-hub.do/10.1016/j.ejps.2019.105042
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2017.04.014
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Nitrogen-Doped Graphene Oxide on the Aging Behavior of Nitrile-Butadiene Rubber.
|title=The Effect of Brushing and Aging on the Staining and Smoothness of Resin Composites.
|date=10.10.2019
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31658636
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28194869
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835680
|full-text-url=https://sci-hub.do/10.1111/jerd.12293
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related dysfunction of the DNA damage response in intestinal stem cells.
|title=Frequency-modulated atomic force microscopy localises viscoelastic remodelling in the ageing sheep aorta.
|date=2019
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31057688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27479890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485179
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020410
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related variations in corneal geometry and their association with astigmatism: The Yamagata Study (Funagata).
|title=Changes in surface characteristics of two different resin composites after 1 year water storage: An SEM and [[AFM]] study.
|date=10.2018
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30412088
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27062131
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221551
|full-text-url=https://sci-hub.do/10.1002/sca.21317
}}
}}
* {{medline-title
* {{medline-title
|title=Sex-related differences in corneal astigmatism and shape with age.
|title=Wide bandwidth nanomechanical assessment of murine cartilage reveals protection of aggrecan knock-in mice from joint-overuse.
|date=09.2018
|date=14.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30077353
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27086115
|full-text-url=https://sci-hub.do/10.1016/j.jcrs.2018.06.020
|full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2016.03.055
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-Resistant Functionalized LDH⁻SAS/Nitrile-Butadiene Rubber Composites: Preparation and Study of Aging Kinetics/Anti-Aging Mechanism.
|title=Effect of at-home bleaching with different thickeners and aging on physical properties of a nanocomposite.
|date=18.05.2018
|date=01-03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29783656
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27011745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978213
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784160
}}
}}
* {{medline-title
* {{medline-title
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA damage and apoptosis in natural ageing rats].
|title=Interaction of intraocular lenses with fibronectin and human lens epithelial cells: Effect of chemical composition and aging.
|date=04.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751716
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26112694
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180115.005
|full-text-url=https://sci-hub.do/10.1002/jbm.a.35528
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in with-the-rule and oblique corneal astigmatism.
|title=β-Hydroxy-β-methylbutyrate (HMB) supplementation and resistance exercise significantly reduce abdominal adiposity in healthy elderly men.
|date=09.2018
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369508
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25700845
|full-text-url=https://sci-hub.do/10.1111/aos.13683
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.02.012
}}
}}
* {{medline-title
* {{medline-title
|title=Investigation of the factors that influence lead accumulation onto polyethylene: Implication for potable water plumbing pipes.
|title=Atomic force microscopy reveals age-dependent changes in nanomechanical properties of the extracellular matrix of native human menisci: implications for joint degeneration and osteoarthritis.
|date=05.04.2018
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29324324
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24972006
|full-text-url=https://sci-hub.do/10.1016/j.jhazmat.2017.12.066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374607
}}
}}
* {{medline-title
* {{medline-title
|title=Global mapping of transcription factor motifs in human aging.
|title=In situ atomic force microscopy analysis of morphology and particle size changes in lithium iron phosphate cathode during discharge.
|date=2018
|date=01.06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29293662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24703680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749797
|full-text-url=https://sci-hub.do/10.1016/j.jcis.2014.02.035
}}
}}
* {{medline-title
* {{medline-title
|title=Cross-Sectional and Longitudinal Investigation of the Power Vector in Astigmatism: The Yamagata Study (Funagata).
|title=Load cycling enhances bioactivity at the resin-dentin interface.
|date=01.2018
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29095754
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24630703
|full-text-url=https://sci-hub.do/10.1097/ICO.0000000000001418
|full-text-url=https://sci-hub.do/10.1016/j.dental.2014.02.009
}}
}}
* {{medline-title
==GSC==
|title=Glomerular and tubular effects of nitric oxide (NO) are regulated by angiotensin II (Ang II) in an age-dependent manner through activation of both angiotensin receptors (AT1Rs and AT2Rs) in conscious lambs.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28861607
|full-text-url=https://sci-hub.do/10.1007/s00424-017-2053-4
}}
==LPA==


* {{medline-title
* {{medline-title
|title=Ginseng gintonin, aging societies, and geriatric brain diseases.
|title=[i]mastermind[/i] regulates niche ageing independently of the [i]Notch[/i] pathway in the [i]Drosophila[/i] ovary.
|date=03.2021
|date=29.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32817818
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31744422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426447
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893403
}}
}}
* {{medline-title
* {{medline-title
|title=Late-life related subtypes of depression - a data-driven approach on cognitive domains and physical frailty.
|title=Germline stem cell homeostasis.
|date=22.05.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32442243
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31155359
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa110
|full-text-url=https://sci-hub.do/10.1016/bs.ctdb.2019.04.006
}}
}}
* {{medline-title
* {{medline-title
|title=Does sedentary time increase in older adults in the days following participation in intense exercise?
|title=Endocrine regulation of female germline stem cells in the fruit fly Drosophila melanogaster.
|date=12.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32130714
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109668
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01502-6
|full-text-url=https://sci-hub.do/10.1016/j.cois.2018.07.001
}}
}}
* {{medline-title
* {{medline-title
|title=Association of Long-term Exposure to Elevated Lipoprotein(a) Levels With Parental Life Span, Chronic Disease-Free Survival, and Mortality Risk: A Mendelian Randomization Analysis.
|title=Generation of Inducible Gene-Switched GAL4 Expressed in the [i]Drosophila[/i] Female Germline Stem Cell Niche.
|date=05.02.2020
|date=05.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32108890
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31018943
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049087
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553524
}}
}}
* {{medline-title
* {{medline-title
|title=Elevated Autotaxin and [[LPA]] Levels During Chronic Viral Hepatitis and Hepatocellular Carcinoma Associate with Systemic Immune Activation.
|title=YAP/Yorkie in the germline modulates the age-related decline of germline stem cells and niche cells.
|date=25.11.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31769428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30943201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447158
}}
}}
* {{medline-title
* {{medline-title
|title=Lysophosphatidic acid receptor [[LPA]]  prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome.
|title=Diminished Jak/STAT Signaling Causes Early-Onset Aging Defects in Stem Cell Cytokinesis.
|date=01.2020
|date=21.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31714004
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30612906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974717
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783278
}}
}}
* {{medline-title
* {{medline-title
|title=Associations of Sedentary and Physically-Active Behaviors With Cognitive-Function Decline in Community-Dwelling Older Adults: Compositional Data Analysis From the NEIGE Study.
|title=JNK signaling triggers spermatogonial dedifferentiation during chronic stress to maintain the germline stem cell pool in the [i]Drosophila[/i] testis.
|date=05.11.2020
|date=09.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31656243
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29985130
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070334
}}
}}
* {{medline-title
* {{medline-title
|title=Validation and comparison of two automated methods for quantifying brain white matter hyperintensities of presumed vascular origin.
|title=Age-related differences in BOLD modulation to cognitive control costs in a multitasking paradigm: Global switch, local switch, and compatibility-switch costs.
|date=02.2020
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31612759
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29414492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607266
|full-text-url=https://sci-hub.do/10.1016/j.neuroimage.2018.01.030
}}
}}
* {{medline-title
* {{medline-title
|title=The Sedentary Time and Physical Activity Levels on Physical Fitness in the Elderly: A Comparative Cross Sectional Study.
|title=Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture.
|date=01.10.2019
|date=22.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31581429
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196443
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894940
}}
}}
* {{medline-title
* {{medline-title
|title=Light-Intensity Physical Activity in a Large Prospective Cohort of Older US Adults: A 21-Year Follow-Up of Mortality.
|title=Loss of [i]foxo[/i] rescues stem cell aging in [i]Drosophila[/i] germ line.
|date=2020
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31600755
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28925355
|full-text-url=https://sci-hub.do/10.1159/000502860
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644957
}}
}}
* {{medline-title
* {{medline-title
|title=The Impact of Movement Behaviors on Bone Health in Elderly with Adequate Nutritional Status: Compositional Data Analysis Depending on the Frailty Status.
|title=DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation.
|date=09.03.2019
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30857291
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28410423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409174
}}
}}
* {{medline-title
* {{medline-title
|title=Compositional Influence of Movement Behaviors on Bone Health during Aging.
|title=Antithrombotic agents intake prior to injury does not affect outcome after a traumatic brain injury in hospitalized elderly patients.
|date=08.2019
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30829961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28110930
|full-text-url=https://sci-hub.do/10.1249/MSS.0000000000001972
|full-text-url=https://sci-hub.do/10.1016/j.jocn.2016.12.032
}}
}}
* {{medline-title
* {{medline-title
|title=Duration-Response of Light-Intensity Physical Activity and Glucose Dynamics in Older Adults.
|title=Suberoylanilide hydroxamic acid represses glioma stem-like cells.
|date=01.01.2019
|date=18.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526273
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27863490
|full-text-url=https://sci-hub.do/10.1123/jpah.2017-0557
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116136
}}
}}
* {{medline-title
* {{medline-title
|title=Accelerometer-Measured Physical Activity and Sedentary Behavior: A Cross-Sectional Study of Brazilian Older Adults.
|title=Flavonoids and darkness lower PCD in senescing Vitis vinifera suspension cell cultures.
|date=01.11.2018
|date=26.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27782806
|full-text-url=https://sci-hub.do/10.1123/jpah.2017-0456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080730
}}
}}
* {{medline-title
* {{medline-title
|title=The Association Between Physical Activity, Including Physical Activity Intensity, and Fear of Falling Differs by Fear Severity in Older Adults Living in the Community.
|title=DNA damage-induced Lok/CHK2 activation compromises germline stem cell self-renewal and lineage differentiation.
|date=16.04.2020
|date=01.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30219902
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27729408
|full-text-url=https://sci-hub.do/10.1093/geronb/gby103
|full-text-url=https://sci-hub.do/10.1242/dev.141069
}}
}}
* {{medline-title
* {{medline-title
|title=Gintonin Attenuates D-Galactose-Induced Hippocampal Senescence by Improving Long-Term Hippocampal Potentiation, Neurogenesis, and Cognitive Functions.
|title=The Wnt pathway limits BMP signaling outside of the germline stem cell niche in Drosophila ovaries.
|date=2018
|date=01.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30138913
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27364467
|full-text-url=https://sci-hub.do/10.1159/000491113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001506
}}
}}
* {{medline-title
* {{medline-title
|title=Associations of distinct levels of physical activity with mobility in independent healthy older women.
|title=Nuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations.
|date=09.2018
|date=01-03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27073739
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.06.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805359
}}
}}
* {{medline-title
* {{medline-title
|title=Reallocating Accelerometer-Assessed Sedentary Time to Light or Moderate- to Vigorous-Intensity Physical Activity Reduces Frailty Levels in Older Adults: An Isotemporal Substitution Approach in the TSHA Study.
|title=Senescence from glioma stem cell differentiation promotes tumor growth.
|date=02.2018
|date=05.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29269096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26775840
|full-text-url=https://sci-hub.do/10.1016/j.jamda.2017.11.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176357
}}
}}
* {{medline-title
* {{medline-title
|title=Lean psoas area does not correlate with clinical outcomes in moderately to severely injured older people.
|title=Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence.
|date=03.2018
|date=24.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29168295
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26196144
|full-text-url=https://sci-hub.do/10.1111/ajag.12482
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541496
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide meta-analysis associates HLA-DQA1/DRB1 and [[LPA]] and lifestyle factors with human longevity.
|title=Microglial voltage-gated sodium channels modulate cellular response in Alzheimer's disease--a new perspective on an old problem.
|date=13.10.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29030599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715013
}}
==CD27==


* {{medline-title
|title=The Interplay between [[CD27]]  and [[CD27]]  B Cells Ensures the Flexibility, Stability, and Resilience of Human B Cell Memory.
|date=03.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32130900
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2020.02.022
}}
}}
* {{medline-title
* {{medline-title
|title=CMV-independent increase in [[CD27]]-CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians.
|title=Y-27632, a ROCK inhibitor, delays senescence of putative murine salivary gland stem cells in culture.
|date=2020
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31993214
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25804560
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972903
|full-text-url=https://sci-hub.do/10.1016/j.archoralbio.2015.03.003
}}
}}
* {{medline-title
* {{medline-title
|title=Compartmentalized cytotoxic immune response leads to distinct pathogenic roles of natural killer and senescent CD8  T cells in human cutaneous leishmaniasis.
|title=Notch signaling mediates the age-associated decrease in adhesion of germline stem cells to the niche.
|date=04.2020
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31925782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25521289
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270478
}}
}}
* {{medline-title
* {{medline-title
|title=[[CD27]]- IgD- B cell memory subset associates with inflammation and frailty in elderly individuals but only in males.
|title=Aging and insulin signaling differentially control normal and tumorous germline stem cells.
|date=2019
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31423147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25470527
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326914
}}
}}
* {{medline-title
* {{medline-title
|title=Are skin senescence and immunosenescence linked within individuals?
|title=[The opportunity to use combined stem cells transplantation for haemopoesis activation in the old and mature laboratory animals under the conditions of ionizing radiation].
|date=08.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31062498
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25306670
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612632
 
}}
}}
==HGF==
* {{medline-title
* {{medline-title
|title=Circulating Senescent T Cells Are Linked to Systemic Inflammation and Lesion Size During Human Cutaneous Leishmaniasis.
|title=Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4  T cell subsets.
|date=2018
|date=19.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30662437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33223447
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328442
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155367
}}
}}
* {{medline-title
* {{medline-title
|title=Low IL-2 Expressing T Cells in Thalassemia Major Patients: Is It Immune Aging.
|title=Hepatocyte growth factor ([[HGF]]) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling pathways.
|date=10.2018
|date=31.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30369736
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736659
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393921
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence markers: Predictive for response to checkpoint inhibitors.
|title=Phenytoin sodium-ameliorated gingival fibroblast aging is associated with autophagy.
|date=01.03.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30151962
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32281104
|full-text-url=https://sci-hub.do/10.1002/ijc.31763
|full-text-url=https://sci-hub.do/10.1111/jre.12750
}}
}}
* {{medline-title
* {{medline-title
|title=Features of Immunosenescence in Women Newly Diagnosed With Breast Cancer.
|title=Impaired integrin α  /β  -mediated hepatocyte growth factor release by stellate cells of the aged liver.
|date=2018
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061900
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32157808
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189994
}}
}}
* {{medline-title
* {{medline-title
|title=Age, calorie restriction, and age of calorie restriction onset reduce maturation of natural killer cells in C57Bl/6 mice.
|title=Evaluation of the biological behaviour of various dental implant abutment materials on attachment and viability of human gingival fibroblasts.
|date=07.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29914631
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31060818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011236
|full-text-url=https://sci-hub.do/10.1016/j.dental.2019.04.010
}}
}}
* {{medline-title
* {{medline-title
|title=CD57 identifies T cells with functional senescence before terminal differentiation and relative telomere shortening in patients with activated [[PI3]] kinase delta syndrome.
|title=Characterization of aged rat vocal fold fibroblasts.
|date=11.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29790605
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30450675
|full-text-url=https://sci-hub.do/10.1111/imcb.12169
|full-text-url=https://sci-hub.do/10.1002/lary.27464
}}
}}
* {{medline-title
* {{medline-title
|title=An immunological age index in bipolar disorder: A confirmatory factor analysis of putative immunosenescence markers and associations with clinical characteristics.
|title=Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults.
|date=12.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29691917
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354979
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101979
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood.
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging.
|date=06.2018
|date=26.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29505809
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2018.02.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848
}}
}}
* {{medline-title
* {{medline-title
|title=Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low [[PAX5]].
|title=Hepatocyte growth factor is a potential biomarker for osteoproliferation and osteoporosis in ankylosing spondylitis.
|date=08.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29425852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30306221
|full-text-url=https://sci-hub.do/10.1016/j.clim.2018.02.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449322
}}
}}
* {{medline-title
* {{medline-title
|title=Dynamics of [[CD4]] and CD8 T-Cell Subsets and Inflammatory Biomarkers during Early and Chronic HIV Infection in Mozambican Adults.
|title=Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor.
|date=2017
|date=09.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29354131
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29523193
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760549
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845161
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic influence on splenic natural killer cell frequencies and maturation among aged mice.
|title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway.
|date=04.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29355703
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.01.010
|full-text-url=https://sci-hub.do/10.1159/000487559
}}
}}
* {{medline-title
* {{medline-title
|title=Increased senescent CD8+ T cells in the peripheral blood mononuclear cells of Behçet's disease patients.
|title=Cell-size-dependent upregulation of [[HGF]] expression in dermal fibroblasts: Impact on human skin connective tissue aging.
|date=03.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29255925
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28826691
|full-text-url=https://sci-hub.do/10.1007/s00403-017-1802-8
|full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2017.08.003
}}
}}
* {{medline-title
* {{medline-title
|title=T-cell differentiation and CD56+ levels in polypoidal choroidal vasculopathy and neovascular age-related macular degeneration.
|title=Oxidative stress contributes to hepatocyte growth factor-dependent pro-senescence activity of ovarian cancer cells.
|date=20.11.2017
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29165313
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28652056
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723695
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.06.015
}}
}}
* {{medline-title
* {{medline-title
|title=Human CD8  EMRA T cells display a senescence-associated secretory phenotype regulated by p38 MAPK.
|title=Estrogen modulates mesenchyme-epidermis interactions in the adult nipple.
|date=02.2018
|date=15.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28289136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399661
}}
}}
==EGF==
* {{medline-title
* {{medline-title
|title=Acute, exercise-induced alterations in cytokines and chemokines in the blood distinguish physically active and sedentary aging.
|title=Enhanced Functional Recovery from Spinal Cord Injury in Aged Mice after Stem Cell Transplantation through [[HGF]] Induction.
|date=08.12.2020
|date=14.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33289019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28216143
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa310
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355635
}}
}}
* {{medline-title
* {{medline-title
|title=Proinflammation, profibrosis, and arterial aging.
|title=Necroptosis Induced by Ad-[[HGF]] Activates Endogenous C-Kit  Cardiac Stem Cells and Promotes Cardiomyocyte Proliferation and Angiogenesis in the Infarcted Aged Heart.
|date=09.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33103036
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27941320
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574637
|full-text-url=https://sci-hub.do/10.1159/000453144
}}
}}
* {{medline-title
* {{medline-title
|title=Hinokitiol induces cell death and inhibits epidermal growth factor-induced cell migration and signaling pathways in human cervical adenocarcinoma.
|title=Ovarian cancer-derived ascitic fluids induce a senescence-dependent pro-cancerogenic phenotype in normal peritoneal mesothelial cells.
|date=09.2020
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32917321
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27444787
|full-text-url=https://sci-hub.do/10.1016/j.tjog.2020.07.013
|full-text-url=https://sci-hub.do/10.1007/s13402-016-0289-1
}}
}}
* {{medline-title
* {{medline-title
|title=Activation of epidermal growth factor receptor signaling mediates cellular senescence induced by certain pro-inflammatory cytokines.
|title=Influence of aging on the quantity and quality of human cardiac stem cells.
|date=05.2020
|date=07.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32323422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26947751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253070
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780032
}}
}}
* {{medline-title
* {{medline-title
|title=Insulin Signaling in Intestinal Stem and Progenitor Cells as an Important Determinant of Physiological and Metabolic Traits in [i]Drosophila[/i].
|title=Senescent peritoneal mesothelium induces a pro-angiogenic phenotype in ovarian cancer cells in vitro and in a mouse xenograft model in vivo.
|date=26.03.2020
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32225024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26433963
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740564
}}
}}
* {{medline-title
* {{medline-title
|title=Different cellular properties and loss of nuclear signalling of porcine epidermal growth factor receptor with aging.
|title=Macrophage migration inhibitory factor confers resistance to senescence through [[CD74]]-dependent AMPK-FOXO3a signaling in mesenchymal stem cells.
|date=01.05.2020
|date=22.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32001323
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25896286
|full-text-url=https://sci-hub.do/10.1016/j.ygcen.2020.113415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453287
}}
}}
* {{medline-title
* {{medline-title
|title=Isoform-selective as opposed to complete depletion of fibroblast growth factor 2 (FGF-2) has no major impact on survival and gene expression in [[SOD1]]  amyotrophic lateral sclerosis mice.
|title=Prevention of hair graying by factors that promote the growth and differentiation of melanocytes.
|date=09.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30883949
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25099157
|full-text-url=https://sci-hub.do/10.1111/ejn.14405
|full-text-url=https://sci-hub.do/10.1111/1346-8138.12570
}}
}}
* {{medline-title
* {{medline-title
|title=A novel age-related venous amyloidosis derived from [[EGF]]-containing fibulin-like extracellular matrix protein 1.
|title=Low-power laser irradiation fails to improve liver regeneration in elderly rats at 48 h after 70 % resection.
|date=04.2019
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30565683
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24880927
|full-text-url=https://sci-hub.do/10.1002/path.5203
|full-text-url=https://sci-hub.do/10.1007/s10103-014-1598-0
}}
}}
* {{medline-title
* {{medline-title
|title=[[EGF]]/[[EGF]]R upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence.
|title=Effect of AST on age-associated changes of vocal folds in a rat model.
|date=04.12.2018
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514230
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24764173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426
|full-text-url=https://sci-hub.do/10.1002/lary.24733
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults.
|title=The role of growth factors in maintenance of stemness in bone marrow-derived mesenchymal stem cells.
|date=09.2018
|date=28.02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354979
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24491556
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101979
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.01.084
}}
}}
==SOX2==
 
* {{medline-title
* {{medline-title
|title=The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma.
|title=Multiple nanosecond pulsed electric fields stimulation with conductive poly(l-lactic acid)/carbon nanotubes films maintains the multipotency of mesenchymal stem cells during prolonged in vitro culture.
|date=2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30252623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592324
|full-text-url=https://sci-hub.do/10.1080/09537104.2018.1514110
|full-text-url=https://sci-hub.do/10.1002/term.3088
}}
}}
* {{medline-title
* {{medline-title
|title=Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling.
|title=Subpopulations of miniature pig mesenchymal stromal cells with different differentiation potentials differ in the expression of octamer-binding transcription factor 4 and sex determining region Y-box 2.
|date=02.11.2018
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217816
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32054231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222112
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054621
}}
}}
* {{medline-title
* {{medline-title
|title=Burn wounds in the young versus the aged patient display differential immunological responses.
|title=Increased Type I and Decreased Type II Hair Cells after Deletion of Sox2 in the Developing Mouse Utricle.
|date=09.2018
|date=01.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29895402
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678344
|full-text-url=https://sci-hub.do/10.1016/j.burns.2018.05.012
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2019.09.027
}}
}}
* {{medline-title
* {{medline-title
|title=Precise Intradermal Injection of Nanofat-Derived Stromal Cells Combined with Platelet-Rich Fibrin Improves the Efficacy of Facial Skin Rejuvenation.
|title='Stemness' and 'senescence' related escape pathways are dose dependent in lung cancer cells surviving post irradiation.
|date=2018
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768259
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201845
|full-text-url=https://sci-hub.do/10.1159/000489809
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116562
}}
}}
* {{medline-title
* {{medline-title
|title=[[RPE]] phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells.
|title=Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis.
|date=13.03.2018
|date=30.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29534722
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30910981
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851074
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500153
}}
}}
* {{medline-title
* {{medline-title
|title=Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor.
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|date=09.03.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29523193
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845161
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
}}
}}
* {{medline-title
* {{medline-title
|title=V[[EGF]] Signaling in Neurological Disorders.
|title=Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart.
|date=17.01.2018
|date=07.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29342116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30663680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796221
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207148
}}
}}
* {{medline-title
* {{medline-title
|title=Global analysis of gene expression profiles in the submandibular salivary gland of klotho knockout mice.
|title=A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation.
|date=04.2018
|date=02.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28885690
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168501
}}
}}
* {{medline-title
* {{medline-title
|title=Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans.
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|date=29.08.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854356
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583510
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
}}
}}
==F2==
* {{medline-title
* {{medline-title
|title=Environmental risk assessment of glufosinate-resistant soybean by pollen-mediated gene flow under field conditions in the region of the genetic origin.
|title=Centenarians Overexpress Pluripotency-Related Genes.
|date=17.10.2020
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33189381
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2020.143073
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
}}
}}
* {{medline-title
* {{medline-title
|title=Gestational arsenite exposure augments hepatic tumors of C3H mice by promoting senescence in F1 and [[F2]] offspring via different pathways.
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|date=01.12.2020
|date=10.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010264
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|full-text-url=https://sci-hub.do/10.1016/j.taap.2020.115259
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
}}
}}
* {{medline-title
* {{medline-title
|title=Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone.
|title=[[SOX2]] expression diminishes with ageing in several tissues in mice and humans.
|date=01.07.2020
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32303766
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29574045
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239378
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.03.008
}}
}}
* {{medline-title
* {{medline-title
|title=Conclusions from a behavioral aging study on male and female [[F2]] hybrid mice on age-related behavior, buoyancy in water-based tests, and an ethical method to assess lifespan.
|title=Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.
|date=11.09.2019
|date=15.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31509518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29138277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733499
}}
}}
* {{medline-title
* {{medline-title
|title=In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice.
|title=[[ZSCAN10]] expression corrects the genomic instability of iPSCs from aged donors.
|date=2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31428698
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846095
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692356
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843481
}}
}}
* {{medline-title
* {{medline-title
|title=Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice.
|title=Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts.
|date=09.2019
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31381889
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635509
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576272
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of zirconia surface treatment, resin cement and aging on the load-bearing capacity under fatigue of thin simplified full-contour Y-TZP restorations.
|title=Role of p16  and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells.
|date=09.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085457
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28410532
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2019.04.050
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390672
}}
}}
* {{medline-title
* {{medline-title
|title=Maternal Resveratrol Supplementation Prevents Cognitive Decline in Senescent Mice Offspring.
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells.
|date=06.03.2019
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30845644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429303
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853
}}
}}
* {{medline-title
* {{medline-title
|title=Transgenerational hormetic effects of sublethal dose of flupyradifurone on the green peach aphid, Myzus persicae (Sulzer) (Hemiptera: Aphididae).
|title=The p53 Pathway Controls [[SOX2]]-Mediated Reprogramming in the Adult Mouse Spinal Cord.
|date=2019
|date=11.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677036
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27732862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345466
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094368
}}
}}
* {{medline-title
* {{medline-title
|title=Early treatment of acute hepatitis C infection is cost-effective in HIV-infected men-who-have-sex-with-men.
|title=Sox2-Deficient Müller Glia Disrupt the Structural and Functional Maturation of the Mammalian Retina.
|date=2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30629662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27031842
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328146
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819558
}}
}}
* {{medline-title
* {{medline-title
|title=Adult rat morphine exposure changes morphine preference, anxiety, and the brain expression of dopamine receptors in male offspring.
|title=mTOR inhibition decreases [[SOX2]]-[[SOX9]] mediated glioma stem cell activity and temozolomide resistance.
|date=10.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966738
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26878385
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.06.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898154
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in shock absorption capacity of the human spinal column.
|title=Disentangling the aneuploidy and senescence paradoxes: a study of triploid breast cancers non-responsive to neoadjuvant therapy.
|date=2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29844665
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26860864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963482
|full-text-url=https://sci-hub.do/10.1007/s00418-016-1415-x
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of Supplemental Protein on the Life Expectancy and Reproduction of the Chinese Citrus Fruit Fly, Bactrocera minax (Enderlein) (Tetradacus minax) (Diptera: Tephritidae).
|title=Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide.
|date=01.03.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26102294
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825594
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Cold Storage on Biological Traits of Psix saccharicola (Hymenoptera: Platygastridae), an Egg Parasitoid of Acrosternum arabicum (Hemiptera: Pentatomidae).
|title=Critical role of the miR-200 family in regulating differentiation and proliferation of neurons.
|date=28.05.2018
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25753155
|full-text-url=https://sci-hub.do/10.1093/jee/toy087
|full-text-url=https://sci-hub.do/10.1111/jnc.13089
}}
}}
* {{medline-title
* {{medline-title
|title=Short-Term Genetic Selection for Adolescent Locomotor Sensitivity to Delta9-Tetrahydrocannabinol (THC).
|title=Localization of juxtacrine factor ephrin-B2 in pituitary stem/progenitor cell niches throughout life.
|date=05.2018
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29550900
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25480420
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935564
|full-text-url=https://sci-hub.do/10.1007/s00441-014-2054-y
}}
}}
==BRAF==
* {{medline-title
* {{medline-title
|title=Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice.
|title=Conditional reprograming culture conditions facilitate growth of lower grade glioma models.
|date=14.03.2018
|date=01.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540228
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33258947
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851307
|full-text-url=https://sci-hub.do/10.1093/neuonc/noaa263
}}
}}
* {{medline-title
* {{medline-title
|title=[[F2]]-Isoprostanes Reflect Oxidative Stress Correlated With Lean Mass and Bone Density but Not Insulin Resistance.
|title=Active notch protects MAPK activated melanoma cell lines from MEK inhibitor cobimetinib.
|date=01.05.2017
|date=14.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29264499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33202284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686621
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2020.111006
}}
}}
* {{medline-title
* {{medline-title
|title=Multigenerational effects of 4-methylbenzylidene camphor (4-MBC) on the survival, development and reproduction of the marine copepod Tigriopus japonicus.
|title=Mitochondrial metabolic reprograming via [[BRAF]] inhibition ameliorates senescence.
|date=01.2018
|date=15.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172130
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31421186
|full-text-url=https://sci-hub.do/10.1016/j.aquatox.2017.11.008
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110691
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Aging on Vocal Fundamental Frequency and Vowel Formants in Men and Women.
|title=Deciphering the genotype and phenotype of hairy cell leukemia: clues for diagnosis and treatment.
|date=09.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28864082
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282776
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832520
|full-text-url=https://sci-hub.do/10.1080/1744666X.2019.1641405
}}
}}
==NHS==
* {{medline-title
* {{medline-title
|title=Telomerase Activation to Reverse Immunosenescence in Elderly Patients With Acute Coronary Syndrome: Protocol for a Randomized Pilot Trial.
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient.
|date=23.09.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32965237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542409
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7
}}
}}
* {{medline-title
* {{medline-title
|title=Factors associated with COVID-19-related death using OpenSAFELY.
|title=Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf -Induced Tumorigenesis.
|date=08.2020
|date=11.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32640463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753828
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2521-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636642
}}
}}
* {{medline-title
* {{medline-title
|title=Advanced ophthalmic nurse practitioners: the potential to improve outcomes for older people with cataracts.
|title=Acquired resistance to [[BRAF]]i reverses senescence-like phenotype in mutant [[BRAF]] melanoma.
|date=17.06.2020
|date=07.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32548985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30159130
|full-text-url=https://sci-hub.do/10.7748/nop.2020.e1229
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112757
}}
}}
* {{medline-title
* {{medline-title
|title=Patient Satisfaction in the Spanish National Health Service: Partial Least Squares Structural Equation Modeling.
|title=Cancer modeling by Transgene Electroporation in Adult Zebrafish (TEAZ).
|date=04.12.2019
|date=27.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31817147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061297
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950388
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177007
}}
}}
* {{medline-title
* {{medline-title
|title=Heart failure with preserved ejection fraction (HFpEF) pathophysiology study (IDENTIFY-HF): does increased arterial stiffness associate with HFpEF, in addition to ageing and vascular effects of comorbidities? Rationale and design.
|title=Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement.
|date=19.11.2019
|date=05.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31748285
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886989
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788639
}}
}}
* {{medline-title
* {{medline-title
|title=Challenges to concordance: theories that explain variations in patient responses.
|title=Impact of Age on Outcomes with Immunotherapy for Patients with Melanoma.
|date=02.10.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31604052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28476944
|full-text-url=https://sci-hub.do/10.12968/bjcn.2019.24.10.466
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553960
}}
}}
* {{medline-title
* {{medline-title
|title=Optimism is associated with exceptional longevity in 2 epidemiologic cohorts of men and women.
|title=Establishment and application of a novel patient-derived KIAA1549:[[BRAF]]-driven pediatric pilocytic astrocytoma model for preclinical drug testing.
|date=10.09.2019
|date=14.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31451635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28002790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744861
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355278
}}
}}
* {{medline-title
* {{medline-title
|title=Reducing readmission rates through a discharge follow-up service.
|title=Detection of Reactive Oxygen Species in Cells Undergoing Oncogene-Induced Senescence.
|date=06.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31363517
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27812875
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616175
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-6670-7_13
}}
}}
* {{medline-title
* {{medline-title
|title=The cost burden of falls in people with glaucoma in National Health Service Hospital Trusts in the UK.
|title=GBM-associated mutations and altered protein expression are more common in young patients.
|date=01.2020
|date=25.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31322025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614
|full-text-url=https://sci-hub.do/10.1080/13696998.2019.1646262
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491
}}
}}
* {{medline-title
* {{medline-title
|title=How Do General Practitioners (GPs) Engage in Falls Prevention With Older People? A Pilot Survey of GPs in [[NHS]] England Suggests a Gap in Routine Practice to Address Falls Prevention.
|title=What makes oncogenes mutually exclusive?
|date=2019
|date=03.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915322
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27416373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421941
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584735
}}
}}
* {{medline-title
* {{medline-title
|title=Fruit and vegetable consumption, cigarette smoke, and leukocyte mitochondrial DNA copy number.
|title=Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression.
|date=01.02.2019
|date=05.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30721920
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27052162
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826807
}}
}}
* {{medline-title
* {{medline-title
|title=Where are we now in perioperative medicine? Results from a repeated UK survey of geriatric medicine delivered services for older people.
|title=Combination with γ-secretase inhibitor prolongs treatment efficacy of [[BRAF]] inhibitor in [[BRAF]]-mutated melanoma cells.
|date=01.05.2019
|date=28.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30624577
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27000992
|full-text-url=https://sci-hub.do/10.1093/ageing/afy218
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2016.03.028
}}
}}
* {{medline-title
* {{medline-title
|title=PATCH: posture and mobility training for care staff versus usual care in care homes: study protocol for a randomised controlled trial.
|title=Parthenolide induces [[MITF]]-M downregulation and senescence in patient-derived [[MITF]]-M(high) melanoma cell populations.
|date=24.09.2018
|date=23.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30249295
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26824319
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891023
}}
}}
* {{medline-title
* {{medline-title
|title=Predictive model of length of stay in hospital among older patients.
|title=Encorafenib (LGX818), a potent [[BRAF]] inhibitor, induces senescence accompanied by autophagy in [[BRAF]]V600E melanoma cells.
|date=07.2019
|date=28.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30191455
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26586345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589144
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2015.11.015
}}
}}
* {{medline-title
* {{medline-title
|title=A qualitative study of the determinants of adherence to NICE falls guideline in managing older fallers attending an emergency department.
|title=Novel Therapies for Metastatic Melanoma: An Update on Their Use in Older Patients.
|date=18.07.2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30022394
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26442859
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051952
|full-text-url=https://sci-hub.do/10.1007/s40266-015-0304-7
}}
}}
* {{medline-title
* {{medline-title
|title=Economic evaluations of eHealth technologies: A systematic review.
|title=Expression of tumor-related Rac1b antagonizes B-Raf-induced senescence in colorectal cells.
|date=2018
|date=28.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897921
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341689
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999277
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2015.08.027
}}
}}
* {{medline-title
* {{medline-title
|title=Shifting to triple value healthcare: Reflections from England.
|title=Trametinib radiosensitises RAS- and [[BRAF]]-mutated melanoma by perturbing cell cycle and inducing senescence.
|date=02.2018
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29402597
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26163092
|full-text-url=https://sci-hub.do/10.1016/j.zefq.2018.01.002
|full-text-url=https://sci-hub.do/10.1016/j.radonc.2015.06.026
}}
}}
* {{medline-title
* {{medline-title
|title=Is "end of life" a special case? Connecting Q with survey methods to measure societal support for views on the value of life-extending treatments.
|title=Near-genomewide RNAi screening for regulators of [[BRAF]](V600E) -induced senescence identifies [[RASEF]], a gene epigenetically silenced in melanoma.
|date=05.2018
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29349842
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24703243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900899
|full-text-url=https://sci-hub.do/10.1111/pcmr.12248
}}
}}
* {{medline-title
* {{medline-title
|title=PERFECTED enhanced recovery (PERFECT-ER) care versus standard acute care for patients admitted to acute settings with hip fracture identified as experiencing confusion: study protocol for a feasibility cluster randomized controlled trial.
|title=Oncogene-induced senescence distinguishes indolent from aggressive forms of pulmonary and non-pulmonary Langerhans cell histiocytosis.
|date=04.12.2017
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29202786
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24471909
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715500
|full-text-url=https://sci-hub.do/10.3109/10428194.2014.887713
}}
}}
==WRN==
==CD36==


* {{medline-title
* {{medline-title
|title=The Impact of Vitamin C on Different System Models of Werner Syndrome.
|title=Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease.
|date=17.11.2020
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33202145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32638492
|full-text-url=https://sci-hub.do/10.1089/ars.2020.8147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431823
}}
}}
* {{medline-title
* {{medline-title
|title=[[WRN]] modulates translation by influencing nuclear mRNA export in HeLa cancer cells.
|title=Reduction of senescence-associated beta-galactosidase activity by vitamin E in human fibroblasts depends on subjects' age and cell passage number.
|date=14.10.2020
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33054770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32479666
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557079
|full-text-url=https://sci-hub.do/10.1002/biof.1636
}}
}}
* {{medline-title
* {{medline-title
|title=MIB1-mediated degradation of [[WRN]] promotes cellular senescence in response to camptothecin treatment.
|title=Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system.
|date=09.2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32652764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32030468
|full-text-url=https://sci-hub.do/10.1096/fj.202000268RRR
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181452
}}
}}
* {{medline-title
* {{medline-title
|title=A Case Report of Werner's Syndrome With a Novel Mutation From India.
|title=Human bone marrow adipocytes display distinct immune regulatory properties.
|date=08.05.2020
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32528764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327694
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711052
}}
}}
* {{medline-title
* {{medline-title
|title=Evidence for premature aging in a Drosophila model of Werner syndrome.
|title=Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken.
|date=11.2019
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31518666
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935377
|full-text-url=https://sci-hub.do/10.3382/ps/pez249
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes.
|title=Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis.
|date=10.2019
|date=22.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.12.025
}}
}}
* {{medline-title
* {{medline-title
|title=Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases.
|title=The adhesion and migration of microglia to β-amyloid (Aβ) is decreased with aging and inhibited by Nogo/NgR pathway.
|date=06.2019
|date=20.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666569
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30029608
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09798-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054753
}}
}}
* {{medline-title
* {{medline-title
|title=Werner Syndrome Protein and DNA Replication.
|title=Cell-surface phenotyping identifies [[CD36]] and CD97 as novel markers of fibroblast quiescence in lung fibrosis.
|date=02.11.2018
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274846
|full-text-url=https://sci-hub.do/10.1152/ajplung.00439.2017
}}
}}
* {{medline-title
* {{medline-title
|title=A case report of Werner's syndrome with bilateral juvenile cataracts.
|title=An evolutionary transcriptomics approach links [[CD36]] to membrane remodeling in replicative senescence.
|date=14.08.2018
|date=06.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107835
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29974107
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092780
|full-text-url=https://sci-hub.do/10.1039/c8mo00099a
}}
* {{medline-title
|title=Comparative analysis of endothelial cell and sub-endothelial cell elastic moduli in young and aged mice: Role of [[CD36]].
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29954596
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083865
}}
}}
* {{medline-title
* {{medline-title
|title=Genomic instability and DNA replication defects in progeroid syndromes.
|title=[[CD36]] initiates the secretory phenotype during the establishment of cellular senescence.
|date=31.12.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29936894
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29777051
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000143
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989758
}}
}}
* {{medline-title
* {{medline-title
|title=Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome.
|title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation.
|date=10.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29908963
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2018.06.007
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797
}}
}}
* {{medline-title
* {{medline-title
|title=Acidic domain of [[WRN]]p is critical for autophagy and up-regulates age associated proteins.
|title=Developmental differences between neonatal and adult human erythropoiesis.
|date=08.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29800817
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29274096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842122
}}
}}
* {{medline-title
* {{medline-title
|title=RECQ helicase disease and related progeroid syndromes: RECQ2018 meeting.
|title=Effects of high-fat diet and age on the blood lipidome and circulating endocannabinoids of female C57BL/6 mice.
|date=07.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29752965
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986283
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217841
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2017.09.011
}}
}}
* {{medline-title
* {{medline-title
|title=Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome.
|title=Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain.
|date=04.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476423
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28713239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492660
}}
}}
* {{medline-title
* {{medline-title
|title=Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant [[WRN]] protein.
|title=Thyroid hormone-stimulated increases in [[PGC]]-1α and [[UCP2]] promote life history-specific endocrine changes and maintain a lipid-based metabolism.
|date=07.2018
|date=01.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27903512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998970
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336568
}}
}}
* {{medline-title
* {{medline-title
|title=Werner syndrome ([[WRN]]) gene variants and their association with altered function and age-associated diseases.
|title=The Drosophila [[CD36]] Homologue croquemort Is Required to Maintain Immune and Gut Homeostasis during Development and Aging.
|date=01.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146545
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27780230
|full-text-url=https://sci-hub.do/10.1016/j.arr.2017.11.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079587
}}
}}
* {{medline-title
* {{medline-title
|title=Human RecQL4 helicase plays multifaceted roles in the genomic stability of normal and cancer cells.
|title=Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology.
|date=28.01.2018
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27723233
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2017.10.021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242297
}}
}}
* {{medline-title
* {{medline-title
|title=Recent Advances in Understanding Werner Syndrome.
|title=Modulation of Macrophage Polarization and [[HMGB1]]-TLR2/[[TLR4]] Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice.
|date=2017
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29043077
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27070323
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621106
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829159
}}
}}
* {{medline-title
* {{medline-title
|title=Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans.
|title=Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice.
|date=19.09.2017
|date=15.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28934497
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26592663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766164
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.11.064
}}
}}
==CD14==
* {{medline-title
* {{medline-title
|title=Human innate immune cell crosstalk induces melanoma cell senescence.
|title=Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone.
|date=30.08.2020
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32939325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24760536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470184
|full-text-url=https://sci-hub.do/10.1530/EJE-14-0006
}}
}}
* {{medline-title
* {{medline-title
|title=Fusion Potential of Human Osteoclasts In Vitro Reflects Age, Menopause, and In Vivo Bone Resorption Levels of Their Donors-A Possible Involvement of DC-STAMP.
|title=Increased hepatic [[CD36]] expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease.
|date=02.09.2020
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32887359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24751397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504560
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032795
}}
}}
* {{medline-title
* {{medline-title
|title=Association of [[CD14]] with incident dementia and markers of brain aging and injury.
|title=Long-term vitamin E supplementation reduces atherosclerosis and mortality in Ldlr-/- mice, but not when fed Western style diet.
|date=21.01.2020
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31818907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24529144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028145
}}
}}
==CIT==
* {{medline-title
* {{medline-title
|title=Compromised Bone Healing in Aged Rats Is Associated With Impaired M2 Macrophage Function.
|title=Effect of sex on aging-related decline of dopamine transporter in healthy subjects.
|date=2019
|date=14.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31681320
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33052524
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813416
|full-text-url=https://sci-hub.do/10.1007/s12149-020-01538-8
}}
}}
* {{medline-title
* {{medline-title
|title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity.
|title=The Relationship Between the Striatal Dopaminergic Neuronal and Cognitive Function With Aging.
|date=08.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32184717
|full-text-url=https://sci-hub.do/10.1089/cell.2019.0010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058549
}}
}}
* {{medline-title
* {{medline-title
|title=Increased monocyte activation with age among HIV-infected long term non-progressor children: implications for early treatment initiation.
|title=Initial Dietary Protein Intake Influence Muscle Function Adaptations in Older Men and Women Following High-Intensity Interval Training Combined with Citrulline.
|date=09.2019
|date=22.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31131542
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31336654
|full-text-url=https://sci-hub.do/10.1111/hiv.12751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683270
}}
}}
* {{medline-title
* {{medline-title
|title=Wheat seed ageing viewed through the cellular redox environment and changes in pH.
|title=I-FP-[[CIT]] striatal binding ratios do not decrease significantly with age in older adults.
|date=06.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092082
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30900103
|full-text-url=https://sci-hub.do/10.1080/10715762.2019.1620226
|full-text-url=https://sci-hub.do/10.1007/s12149-019-01352-x
}}
}}
* {{medline-title
|title=Effect of High-Intensity Interval Training Combined with L-Citrulline Supplementation on Functional Capacities and Muscle Function in Dynapenic-Obese Older Adults.
|date=17.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30562948
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306942
}}
* {{medline-title
* {{medline-title
|title=Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV-Positive Individuals.
|title=The Six-Item Cognitive Impairment Test Is Associated with Adverse Outcomes in Acutely Hospitalized Older Patients: A Prospective Cohort Study.
|date=26.02.2019
|date=05-08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30586719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30140275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957233
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103363
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro.
|title=Dopaminergic imaging separates normal pressure hydrocephalus from its mimics.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30155736
|full-text-url=https://sci-hub.do/10.1007/s00415-018-9029-y
}}
* {{medline-title
|title=Lower Cognitive Function in Older Patients with Lower Muscle Strength and Muscle Mass.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30408092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29913450
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067649
}}
}}
* {{medline-title
* {{medline-title
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|title=Citrulline counteracts overweight- and aging-related effects on adiponectin and leptin gene expression in rat white adipose tissue.
|date=05.07.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632824
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889428
}}
}}
* {{medline-title
* {{medline-title
|title=Serum Zonulin and Endotoxin Levels in Exceptional Longevity versus Precocious Myocardial Infarction.
|title=Overcoming Barriers of Age to Enhance Efficacy of Cancer Immunotherapy: The Clout of the Extracellular Matrix.
|date=04.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896420
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837988
}}
}}
* {{medline-title
* {{medline-title
|title=Rapid Turnover and High Production Rate of Myeloid Cells in Adult Rhesus Macaques with Compensations during Aging.
|title=Validation of the 6-Item Cognitive Impairment Test and the 4AT test for combined delirium and dementia screening in older Emergency Department attendees.
|date=15.06.2018
|date=01.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28985260
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860384
}}
}}
* {{medline-title
* {{medline-title
|title=Human colostrum action against Giardia lamblia infection influenced by hormones and advanced maternal age.
|title=Octogenarian liver grafts: Is their use for transplant currently justified?
|date=06.2018
|date=07.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656328
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28533667
|full-text-url=https://sci-hub.do/10.1007/s00436-018-5860-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423047
}}
}}
* {{medline-title
* {{medline-title
|title=The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence.
|title=Citrulline stimulates locomotor activity in aged rats: Implication of the dopaminergic pathway.
|date=15.02.2018
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29449647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28526389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833376
|full-text-url=https://sci-hub.do/10.1016/j.nut.2017.01.001
}}
}}
* {{medline-title
* {{medline-title
|title=Aged Chinese-origin rhesus macaques infected with SIV develop marked viremia in absence of clinical disease, inflammation or cognitive impairment.
|title=Age-related effects and gender differences in Japanese healthy controls for [ I] FP-[[CIT]] SPECT.
|date=01.02.2018
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29391069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28382589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796498
|full-text-url=https://sci-hub.do/10.1007/s12149-017-1168-1
}}
}}
* {{medline-title
* {{medline-title
|title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™).
|title=The changes of individual carotid artery wall layer by aging and carotid intima-media thickness value for high risk.
|date=04.2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27420293
|full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7
|full-text-url=https://sci-hub.do/10.1111/1755-5922.12209
}}
}}
* {{medline-title
* {{medline-title
|title=Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study.
|title=Melodic Contour Identification Reflects the Cognitive Threshold of Aging.
|date=22.11.2017
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29165355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27378907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904015
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Effects of Donor Age and Cold Ischemia on Liver Transplantation  Outcomes According to the Severity of Recipient Status.
|date=02.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26499986
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729807
}}
}}
==LBP==
* {{medline-title
* {{medline-title
|title=Lipopolysaccharide binding protein is associated with CVD risk in older adults.
|title=Aging and chronic administration of serotonin-selective reuptake inhibitor citalopram upregulate Sirt4 gene expression in the preoptic area of male mice.
|date=08.09.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32895891
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26442099
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01684-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584971
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-related liver degeneration is associated with increased bacterial endotoxin and lipopolysaccharide binding protein levels.
|title=Effects of aging and gender on striatal and extrastriatal [123I]FP-[[CIT]] binding in Parkinson's disease.
|date=01.04.2020
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32090603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25697414
|full-text-url=https://sci-hub.do/10.1152/ajpgi.00345.2018
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.01.016
}}
}}
* {{medline-title
* {{medline-title
|title=Biomarkers of leaky gut are related to inflammation and reduced physical function in older adults with cardiometabolic disease and mobility limitations.
|title=Dopamine transporter imaging in the aged rat: a [¹²³I]FP-[[CIT]] SPECT study.
|date=12.2019
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654268
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25624150
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925090
|full-text-url=https://sci-hub.do/10.1016/j.nucmedbio.2014.12.020
}}
}}
* {{medline-title
* {{medline-title
|title=Needle-shaped amyloid deposition in rat mammary gland: evidence of a novel amyloid fibril protein.
|title=Uneven age effects of [(18)F]FP-[[CIT]] binding in the striatum of Parkinson's disease.
|date=03.2020
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31615282
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25008292
|full-text-url=https://sci-hub.do/10.1080/13506129.2019.1675623
|full-text-url=https://sci-hub.do/10.1007/s12149-014-0882-1
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Lycium barbarum Polysaccharides on Health and Aging of [i]C. elegans[/i] Depend on [i]daf-12/daf-16[/i].
|title=Citrulline induces fatty acid release selectively in visceral adipose tissue from old rats.
|date=2019
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31583041
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24913603
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754959
|full-text-url=https://sci-hub.do/10.1002/mnfr.201400053
}}
}}
* {{medline-title
* {{medline-title
|title=Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8.
|title=Prognostic factors for kidney allograft survival in the Eurotransplant Senior Program.
|date=10.07.2019
|date=01.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24784838
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620326
|full-text-url=https://sci-hub.do/10.12659/AOT.890125
}}
}}
==DCX==
* {{medline-title
* {{medline-title
|title=Lycium barbarum polysaccharides extend the mean lifespan of Drosophila melanogaster.
|title=GSK-3β activation accelerates early-stage consumption of Hippocampal Neurogenesis in senescent mice.
|date=17.07.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259337
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32863953
|full-text-url=https://sci-hub.do/10.1039/c8fo01751d
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449917
}}
}}
* {{medline-title
* {{medline-title
|title=Height loss but not body composition is related to low back pain in community-dwelling elderlies: Shimane CoHRE study.
|title=Doublecortin and IGF-1R protein levels are reduced in spite of unchanged DNA methylation in the hippocampus of aged rats.
|date=10.05.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31077175
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32236698
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511157
|full-text-url=https://sci-hub.do/10.1007/s00726-020-02834-3
}}
}}
* {{medline-title
* {{medline-title
|title=Aging of mouse intervertebral disc and association with back pain.
|title=Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients.
|date=06.2019
|date=06.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30936040
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31130513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608595
}}
}}
* {{medline-title
* {{medline-title
|title=A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats.
|title=Age-related changes in Ki-67 and [[DCX]] expression in the BALB/ c mouse (Mus Musculus) brain.
|date=19.03.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30892277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461166
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.11.005
}}
}}
* {{medline-title
* {{medline-title
|title=Chen-Style Tai Chi for Individuals (Aged 50 Years Old or Above) with Chronic Non-Specific Low Back Pain: A Randomized Controlled Trial.
|title=Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol.
|date=12.02.2019
|date=11.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30759778
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30201019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388249
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131894
}}
}}
* {{medline-title
* {{medline-title
|title=Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity.
|title=Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice.
|date=11.03.2019
|date=04.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30713071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30181440
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165152
}}
}}
* {{medline-title
* {{medline-title
|title=Factors associated with lumbar disc high-intensity zone (HIZ) on T2-weighted magnetic resonance image: a retrospective study of 3185 discs in 637 patients.
|title=Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning.
|date=04.12.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514333
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29793890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280348
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2018.05.007
}}
}}
* {{medline-title
* {{medline-title
|title=Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration [i]in vivo[/i].
|title=Hippocampal neurogenesis in the C57BL/6J mice at early adulthood following prenatal alcohol exposure.
|date=2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283339
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29164372
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157327
|full-text-url=https://sci-hub.do/10.1007/s11011-017-0156-4
}}
}}
* {{medline-title
* {{medline-title
|title=Use of trunk muscle training and neuromuscular electrical stimulation to reduce pain and disability in an older adult with chronic low back pain: A case report.
|title=Puerarin and Amlodipine Improvement of D-Galactose-Induced Impairments of Behaviour and Neurogenesis in Mouse Dentate Gyrus: Correlation with Glucocorticoid Receptor Expression.
|date=08.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28831640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179941
|full-text-url=https://sci-hub.do/10.1007/s11064-017-2366-x
}}
}}
* {{medline-title
* {{medline-title
|title=Endotoxemia is modulated by quantity and quality of dietary fat in older adults.
|title=Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers.
|date=08.2018
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129737
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28766905
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595679
}}
}}
* {{medline-title
* {{medline-title
|title=Correlates of a Recent History of Disabling Low Back Pain in Community-dwelling Older Persons: The Pain in the Elderly (PAINEL) Study.
|title=Early-life decline in neurogenesis markers and age-related changes of TrkB splice variant expression in the human subependymal zone.
|date=06.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29077624
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28612959
|full-text-url=https://sci-hub.do/10.1097/AJP.0000000000000564
|full-text-url=https://sci-hub.do/10.1111/ejn.13623
}}
}}
* {{medline-title
* {{medline-title
|title=The Effectiveness and Safety of Manual Therapy on Pain and Disability in Older Persons With Chronic Low Back Pain: A Systematic Review.
|title=Dehydroepiandrosterone increases the number and dendrite maturation of doublecortin cells in the dentate gyrus of middle age male Wistar rats exposed to chronic mild stress.
|date=09.2017
|date=15.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29079255
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28062256
|full-text-url=https://sci-hub.do/10.1016/j.jmpt.2017.06.008
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2017.01.007
}}
}}
==NGF==
* {{medline-title
* {{medline-title
|title=Dietary fish hydrolysate supplementation containing n-3 LC-PUFAs and peptides prevents short-term memory and stress response deficits in aged mice.
|title=Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis.
|date=23.09.2020
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32976934
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28007584
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2020.09.022
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2016.12.015
}}
}}
* {{medline-title
* {{medline-title
|title=Imbalance of nerve growth factor metabolism in aging women with overactive bladder syndrome.
|title=Postnatal maturation of mouse medullo-spinal cerebrospinal fluid-contacting neurons.
|date=01.09.2020
|date=20.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32870355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27939302
|full-text-url=https://sci-hub.do/10.1007/s00345-020-03422-6
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2016.11.028
}}
}}
* {{medline-title
* {{medline-title
|title=Parity Attenuates Intraepithelial Corneal Sensory Nerve Loss in Female Mice.
|title=Topiramate Improves Neuroblast Differentiation of Hippocampal Dentate Gyrus in the D-Galactose-Induced Aging Mice via Its Antioxidant Effects.
|date=21.07.2020
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32708332
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27734244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404034
|full-text-url=https://sci-hub.do/10.1007/s10571-016-0424-6
}}
}}
* {{medline-title
* {{medline-title
|title=Cholinergic System and [[NGF]] Receptors: Insights from the Brain of the Short-Lived Fish [i]Nothobranchius furzeri[/i].
|title=Adenosine A1 receptor antagonist mitigates deleterious effects of sleep deprivation on adult neurogenesis and spatial reference memory in rats.
|date=20.06.2020
|date=19.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32575701
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27623393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348706
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2016.09.007
}}
}}
* {{medline-title
* {{medline-title
|title=Retrograde axonal transport of BDNF and pro[[NGF]] diminishes with age in basal forebrain cholinergic neurons.
|title=Sex-Specific Effects of Prenatal Stress on Memory and Markers of Neuronal Activity in Juvenile Rats.
|date=12.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31574357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27372837
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.07.018
|full-text-url=https://sci-hub.do/10.1159/000446981
}}
}}
* {{medline-title
* {{medline-title
|title=C-SH2 point mutation converts p85β regulatory subunit of phosphoinositide 3-kinase to an anti-aging gene.
|title=MeHg Suppressed Neuronal Potency of Hippocampal NSCs Contributing to the Puberal Spatial Memory Deficits.
|date=03.09.2019
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481652
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26743863
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722097
|full-text-url=https://sci-hub.do/10.1007/s12011-015-0609-8
}}
}}
* {{medline-title
* {{medline-title
|title=[i]Hericium erinaceus[/i] Mycelium and Its Isolated Compound, Erinacine A, Ameliorate High-Fat High-Sucrose Diet-Induced Metabolic Dysfunction and Spatial Learning Deficits in Aging Mice.
|title=Hypercrosslinked Additives for Ageless Gas-Separation Membranes.
|date=05.2019
|date=05.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31084539
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26749173
|full-text-url=https://sci-hub.do/10.1089/jmf.2018.4288
|full-text-url=https://sci-hub.do/10.1002/anie.201508070
}}
}}
* {{medline-title
* {{medline-title
|title=Morphological and immunohistochemical characteristics of the equine corneal epithelium.
|title=Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus.
|date=11.2019
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26687232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916041
}}
}}
* {{medline-title
* {{medline-title
|title=Ectopic nerve growth factor prevents proliferation in glioma cells by senescence induction.
|title=Effects of Ginko biloba leaf extract on the neurogenesis of the hippocampal dentate gyrus in the elderly mice.
|date=05.2019
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30417351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26297531
|full-text-url=https://sci-hub.do/10.1002/jcp.27430
|full-text-url=https://sci-hub.do/10.1007/s12565-015-0297-7
}}
}}
* {{medline-title
* {{medline-title
|title=Mechanisms Underlying the Regulation of HP1γ by the [[NGF]]-PKA Signaling Pathway.
|title=Persistent loss of hippocampal neurogenesis and increased cell death following adolescent, but not adult, chronic ethanol exposure.
|date=10.10.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30305677
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24993092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180112
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125431
}}
}}
* {{medline-title
* {{medline-title
|title=Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling.
|title=Lactobacillus pentosus var. plantarum C29 ameliorates memory impairment and inflammaging in a D-galactose-induced accelerated aging mouse model.
|date=02.11.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217816
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24657159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222112
|full-text-url=https://sci-hub.do/10.1016/j.anaerobe.2014.03.003
}}
}}
==F3==
* {{medline-title
* {{medline-title
|title=Nasal delivery of nerve growth factor rescue hypogonadism by up-regulating GnRH and testosterone in aging male mice.
|title=A Comprehensive Analysis of Age and Gender Effects in European Portuguese Oral Vowels.
|date=09.2018
|date=05.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33293174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161474
|full-text-url=https://sci-hub.do/10.1016/j.jvoice.2020.10.021
}}
}}
* {{medline-title
* {{medline-title
|title=Evidence for changing nerve growth factor signalling mechanisms during development, maturation and ageing in the rat molar pulp.
|title=Prenatal exposure to an environmentally relevant phthalate mixture accelerates biomarkers of reproductive aging in a multiple and transgenerational manner in female mice.
|date=02.2019
|date=28.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30099752
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33129917
|full-text-url=https://sci-hub.do/10.1111/iej.12997
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2020.10.009
}}
}}
* {{medline-title
* {{medline-title
|title=Reduced [[NGF]] in Gastric Endothelial Cells Is One of the Main Causes of Impaired Angiogenesis in Aging Gastric Mucosa.
|title=Combining Frontal Transcranial Direct Current Stimulation With Walking Rehabilitation to Enhance Mobility and Executive Function: A Pilot Clinical Trial.
|date=2018
|date=18.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29992182
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32808403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037903
|full-text-url=https://sci-hub.do/10.1111/ner.13250
}}
}}
* {{medline-title
* {{medline-title
|title=Anti-nerve growth factor does not change physical activity in normal young or aging mice but does increase activity in mice with skeletal pain.
|title=Multigenerational exposure to TiO  nanoparticles in soil stimulates stress resistance and longevity of survived C. elegans via activating insulin/IGF-like signaling.
|date=11.2018
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29994990
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32203849
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233725
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2020.114376
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of cerebrolysin on nerve growth factor system in the aging rat brain.
|title=Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice.
|date=2017
|date=12.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31514170
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701766
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781998
}}
}}
* {{medline-title
* {{medline-title
|title=Immunohistochemical localization of nerve growth factor, tropomyosin receptor kinase A, and p75 in the bone and articular cartilage of the mouse femur.
|title=Transgenerational Effects of Extended Dauer Diapause on Starvation Survival and Gene Expression Plasticity in [i]Caenorhabditis elegans[/i].
|date=01-12.2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29166838
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30049782
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724636
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116965
}}
}}
* {{medline-title
* {{medline-title
|title=Differential deregulation of [[NGF]] and [[BDNF]] neurotrophins in a transgenic rat model of Alzheimer's disease.
|title=Influence of Supplemental Protein on the Life Expectancy and Reproduction of the Chinese Citrus Fruit Fly, Bactrocera minax (Enderlein) (Tetradacus minax) (Diptera: Tephritidae).
|date=12.2017
|date=01.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28865749
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718487
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2017.08.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842393
}}
}}
==SDS==
* {{medline-title
* {{medline-title
|title=Semiautomatic morphometric analysis of skeletal muscle obtained by needle biopsy in older adults.
|title=Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice.
|date=12.2020
|date=14.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32946050
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540228
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00266-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851307
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of late-onset dietary intake of salidroside on insulin/insulin-like growth factor-1 (IGF-1) signaling pathway of the annual fish Nothobranchius guentheri.
|title=Multigenerational effects of 4-methylbenzylidene camphor (4-MBC) on the survival, development and reproduction of the marine copepod Tigriopus japonicus.
|date=17.08.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32858432
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172130
|full-text-url=https://sci-hub.do/10.1016/j.archger.2020.104233
|full-text-url=https://sci-hub.do/10.1016/j.aquatox.2017.11.008
}}
}}
* {{medline-title
* {{medline-title
|title=Quantification of Insoluble Protein Aggregation in Caenorhabditis elegans during Aging with a Novel Data-Independent Acquisition Workflow.
|title=Effects of Aging on Vocal Fundamental Frequency and Vowel Formants in Men and Women.
|date=07.08.2020
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32831297
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28864082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519758
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832520
}}
}}
* {{medline-title
* {{medline-title
|title=Skeletal Muscle Myofibrillar Protein Abundance Is Higher in Resistance-Trained Men, and Aging in the Absence of Training May Have an Opposite Effect.
|title=Shedding light on gray(ing) areas: Connectivity and task switching dynamics in aging.
|date=10.01.2020
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31936810
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28323332
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022975
|full-text-url=https://sci-hub.do/10.1111/psyp.12818
}}
}}
* {{medline-title
* {{medline-title
|title=Characterization, evaluation of nutritional parameters of Radix isatidis protein and its antioxidant activity in D-galactose induced ageing mice.
|title=Chronic exposure of zinc oxide nanoparticles causes deviant phenotype in Drosophila melanogaster.
|date=06.11.2019
|date=05.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31694618
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28064146
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836523
|full-text-url=https://sci-hub.do/10.1016/j.jhazmat.2016.12.040
}}
}}
* {{medline-title
* {{medline-title
|title=[Effects of silver nanoparticles on pupation, eclosion, life span, apoptosis and protein expression in Drosophila melanogaster].
|title=Treatment of Chronic Hepatitis C in the Aged - Does It Impact Life Expectancy? A Decision Analysis.
|date=10.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31621246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27410963
|full-text-url=https://sci-hub.do/10.13287/j.1001-9332.201910.036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943667
}}
}}
* {{medline-title
* {{medline-title
|title=Does an Age-Specific Treatment Program Augment the Efficacy of a Cognitive-Behavioral Weight Loss Program in Adolescence and Young Adulthood? Results from a Controlled Study.
|title=Transgenerational programming of longevity and reproduction by post-eclosion dietary manipulation in Drosophila.
|date=02.09.2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31480678
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27025190
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769959
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931857
}}
}}
* {{medline-title
* {{medline-title
|title=Strengths and limitations of Bacillus thuringiensis galleriae for managing Japanese beetle (Popillia japonica) adults and grubs with caveats for cross-order activity to monarch butterfly (Danaus plexippus) larvae.
|title=Spectrographic Acoustic Vocal Characteristics of Elderly Women Engaged in Aerobics.
|date=02.2020
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31240825
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26474716
|full-text-url=https://sci-hub.do/10.1002/ps.5532
|full-text-url=https://sci-hub.do/10.1016/j.jvoice.2015.07.002
}}
}}
* {{medline-title
* {{medline-title
|title=3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism.
|title=Fat and carbohydrate intake over three generations modify growth, metabolism and cardiovascular phenotype in female mice in an age-related manner.
|date=09.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26266533
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.05.024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534415
}}
}}
* {{medline-title
* {{medline-title
|title=Recombinant Buckwheat Trypsin Inhibitor Improves the Protein and Mitochondria Homeostasis in Caenorhabditis elegans Model of Aging and Age-Related Disease.
|title=Effect of semolina-jaggery diet on survival and development of Drosophila melanogaster.
|date=2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31112974
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26252611
|full-text-url=https://sci-hub.do/10.1159/000500156
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594371
}}
}}
* {{medline-title
* {{medline-title
|title=Potential pitfalls in analyzing structural uncoupling of eNOS: aging is not associated with increased enzyme monomerization.
|title=Differential regulation of apoptosis in slow and fast twitch muscles of aged female [[F3]]44BN rats.
|date=01.01.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30289292
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25813803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383358
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375133
}}
}}
* {{medline-title
* {{medline-title
|title=A 2-year longitudinal study of the relationship between masticatory function and progression to frailty or pre-frailty among community-dwelling Japanese aged 65 and older.
|title=Dexmedetomidine and regulation of splenic sympathetic nerve discharge in aged [[F3]]44 rats.
|date=11.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25813893
|full-text-url=https://sci-hub.do/10.1111/joor.12700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451403
}}
}}
* {{medline-title
* {{medline-title
|title=New findings on SNP variants of human protein L-isoaspartyl methyltransferase that affect catalytic activity, thermal stability, and aggregation.
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29856810
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983485
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
}}
* {{medline-title
* {{medline-title
|title=Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models.
|title=Docosahexaenoic acid in Arctic charr (Salvelinus alpinus): the importance of dietary supply and physiological response during the entire growth period.
|date=2018
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25461677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002862
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2014.11.003
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic changes during adult stage in pre-optic, hypothalamus, hippocampus and pituitary regions of female rat brain following neonatal exposure to estradiol-17β.
|title=Starvation-induced transgenerational inheritance of small RNAs in C. elegans.
|date=15.09.2018
|date=17.07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29777688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25018105
|full-text-url=https://sci-hub.do/10.1016/j.ygcen.2018.05.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377509
}}
}}
* {{medline-title
* {{medline-title
|title=Cheap labor: myosin fiber type expression and enzyme activity in the forelimb musculature of sloths (Pilosa: Xenarthra).
|title=Air pollution and gene-specific methylation in the Normative Aging Study: association, effect modification, and mediation analysis.
|date=01.09.2018
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29722617
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24385016
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.01118.2017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053463
}}
}}
==GHR==
* {{medline-title
* {{medline-title
|title=Psychometric Evaluation of the Symptoms of Dementia Screener ([[SDS]]) in a Geriatric Primary Care Population.
|title=Tissue-Specific [[GHR]] Knockout Mice: An Updated Review.
|date=10-12.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29589803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33162937
|full-text-url=https://sci-hub.do/10.1080/07317115.2018.1453906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581730
}}
}}
* {{medline-title
* {{medline-title
|title=The Aggravation of Depression with Aging in Japanese Patients with Subacute Myelo-optico-neuropathy (SMON).
|title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver.
|date=15.08.2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28781313
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596270
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667
}}
}}
==ARC==
* {{medline-title
* {{medline-title
|title=The Polymorphism rs2968 of [i]LSS[/i] Gene Confers Susceptibility to Age-Related Cataract.
|title=Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes.
|date=11.2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32877255
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503129
|full-text-url=https://sci-hub.do/10.1089/dna.2020.5872
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.08.018
}}
}}
* {{medline-title
* {{medline-title
|title=Decreased Anti-Müllerian hormone and Anti-Müllerian hormone receptor type 2 in hypothalami of old Japanese Black cows.
|title=Effects of rapamycin on growth hormone receptor knockout mice.
|date=19.08.2020
|date=13.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29378959
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816183
}}
}}
* {{medline-title
* {{medline-title
|title=Resveratrol delay the cataract formation against naphthalene-induced experimental cataract in the albino rats.
|title=Disruption of the GH receptor gene in adult mice and in insulin sensitive tissues.
|date=01.2020
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31746523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29198419
|full-text-url=https://sci-hub.do/10.1002/jbt.22420
|full-text-url=https://sci-hub.do/10.1016/j.ghir.2017.11.003
}}
}}
* {{medline-title
* {{medline-title
|title=lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/[[TDG]] axis.
|title=The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature.
|date=09.2019
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282110
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28630896
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473676
}}
}}
* {{medline-title
* {{medline-title
|title=Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract.
|title=Differential effects of early-life nutrient restriction in long-lived [[GHR]]-KO and normal mice.
|date=10.05.2019
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31076560
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28523599
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535067
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505892
}}
}}
* {{medline-title
* {{medline-title
|title=Dietary vitamin and carotenoid intake and risk of age-related cataract.
|title=Brain Structure and Function Associated with Younger Adults in Growth Hormone Receptor-Deficient Humans.
|date=01.01.2019
|date=15.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30624584
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28073935
|full-text-url=https://sci-hub.do/10.1093/ajcn/nqy270
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320603
}}
}}
* {{medline-title
* {{medline-title
|title=The impact of [[GJA8]] SNPs on susceptibility to age-related cataract.
|title=Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging.
|date=12.2018
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30349978
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27208894
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410893
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene [[XPC]] in Age-related Cataract.
|title=Growth hormone receptor expression in human gluteal versus abdominal subcutaneous adipose tissue: Association with body shape.
|date=12.10.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30315181
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27015877
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185952
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084456
}}
}}
* {{medline-title
* {{medline-title
|title=Serum selenium levels are associated with age-related cataract.
|title=The somatotropic axis and aging: Benefits of endocrine defects.
|date=25.09.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30260193
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26925766
|full-text-url=https://sci-hub.do/10.26444/aaem/90886
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792645
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic treatment with tributyltin induces sexually dimorphic alterations in the hypothalamic [[POMC]] system of adult mice.
|title=Growth factors, aging and age-related diseases.
|date=12.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30078105
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26883276
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2896-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455771
}}
}}
* {{medline-title
* {{medline-title
|title=Exercise Training Protects Against Aging-Induced Cognitive Dysfunction via Activation of the Hippocampal [[PGC]]-1α/[[FNDC5]]/[[BDNF]] Pathway.
|title=Correlation Analysis Between Expression Levels of Hepatic Growth Hormone Receptor, Janus Kinase 2, Insulin-Like Growth Factor-I Genes and Dwarfism Phenotype in Bama Minipig.
|date=09.2018
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29971668
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26353733
|full-text-url=https://sci-hub.do/10.1007/s12017-018-8500-3
|full-text-url=https://sci-hub.do/10.1166/jnn.2015.9001
}}
}}
* {{medline-title
* {{medline-title
|title=miRNA Long-Term Response to Early Metabolic Environmental Challenge in Hypothalamic Arcuate Nucleus.
|title=Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice.
|date=2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29643765
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26268661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882837
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693470
}}
}}
* {{medline-title
* {{medline-title
|title=β-amyloid expression in age-related cataract lens epithelia and the effect of β-amyloid on oxidative damage in human lens epithelial cells.
|title=Removal of growth hormone receptor ([[GHR]]) in muscle of male mice replicates some of the health benefits seen in global [[GHR]]-/- mice.
|date=2017
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29386875
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26233957
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757856
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543039
}}
}}
* {{medline-title
* {{medline-title
|title=17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior.
|title=Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver.
|date=02.2018
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29168299
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25855408
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394730
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of [[ARC]] ablation on skeletal muscle morphology, function, and apoptotic signaling during aging.
|title=Conservation of pro-longevity genes among mammals.
|date=01.2018
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29056555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25804384
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.10.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457664
}}
}}
* {{medline-title
* {{medline-title
|title=High-throughput sequencing reveals novel lincRNA in age-related cataract.
|title=Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging.
|date=12.2017
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039457
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25789159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716429
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358413
}}
}}
* {{medline-title
* {{medline-title
|title=From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic [[PAK1]]-blockers/longevity-promoters for cancer therapy.
|title=Inflammatory and Glutamatergic Homeostasis Are Involved in Successful Aging.
|date=15.12.2017
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814374
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25711529
|full-text-url=https://sci-hub.do/10.1016/j.ejmech.2017.07.043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864157
}}
}}
==MYC==
* {{medline-title
* {{medline-title
|title=Enhanced proliferative capacity of human preadipocytes achieved by an optimized cultivating method that induces transient activity of hTERT.
|title=Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted ([[GHR]]-KO) mice attenuates phenotypic features of slow aging.
|date=20.08.2020
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32703451
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25244225
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.06.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326932
}}
}}
* {{medline-title
* {{medline-title
|title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity.
|title=Molecular evolution of growth hormone and insulin-like growth factor 1 receptors in long-lived, small-bodied mammals.
|date=10.2019
|date=10.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25065922
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115
|full-text-url=https://sci-hub.do/10.1016/j.gene.2014.07.061
}}
}}
* {{medline-title
* {{medline-title
|title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes.
|title=Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population.
|date=13.06.2019
|date=04.03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24606898
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988204
}}
}}
* {{medline-title
* {{medline-title
|title=Transcriptomic analysis of human IL-7 receptor alpha  and  effector memory CD8  T cells reveals an age-associated signature linked to influenza vaccine response in older adults.
|title=Expression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependent.
|date=08.2019
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044512
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24550353
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296163
}}
}}
==VDR==
* {{medline-title
* {{medline-title
|title=[[SLC1A5]] glutamine transporter is a target of [[MYC]] and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice.
|title=25-Hydroxyvitamin D  positively regulates periodontal inflammaging via SOCS3/STAT signaling in diabetic mice.
|date=06.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909319
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917967
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516164
|full-text-url=https://sci-hub.do/10.1016/j.steroids.2019.108570
}}
}}
* {{medline-title
* {{medline-title
|title=Profound, durable and [[MGMT]]-independent sensitivity of glioblastoma cells to cyclin-dependent kinase inhibition.
|title=1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel [[VDR]]-Ezh2-p16 signal axis.
|date=01.07.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30549269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31880094
|full-text-url=https://sci-hub.do/10.1002/ijc.32069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996957
}}
}}
* {{medline-title
* {{medline-title
|title=[[MYC]] and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts.
|title=Active vitamin D impedes the progression of non-alcoholic fatty liver disease by inhibiting cell senescence in a rat model.
|date=2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526305
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31810868
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343716
|full-text-url=https://sci-hub.do/10.1016/j.clinre.2019.10.007
}}
}}
* {{medline-title
* {{medline-title
|title=A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation.
|title=Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H O -induced apoptosis in rat intervertebral disc cells.
|date=02.10.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279449
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30905826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168501
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.013
}}
}}
* {{medline-title
* {{medline-title
|title=O-GlcNAcylation is required for mutant [[KRAS]]-induced lung tumorigenesis.
|title=Vitamin D Receptor in Muscle Atrophy of Elderly Patients: A Key Element of Osteoporosis-Sarcopenia Connection.
|date=01.11.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130254
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284754
}}
}}
* {{medline-title
* {{medline-title
|title=Centenarians Overexpress Pluripotency-Related Genes.
|title=Reduced vitamin D receptor ([[VDR]]) expression and plasma vitamin D levels are associated with aging-related prostate lesions.
|date=16.08.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29508414
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
|full-text-url=https://sci-hub.do/10.1002/pros.23498
}}
}}
* {{medline-title
* {{medline-title
|title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16  and Wild-Type p53.
|title=[[VDR]] Activation Reduces Proteinuria and High-Glucose-Induced Injury of Kidneys and Podocytes by Regulating Wnt Signaling Pathway.
|date=2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28848172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985
|full-text-url=https://sci-hub.do/10.1159/000480315
}}
}}
* {{medline-title
* {{medline-title
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|title=Vitamin D and the brain: Genomic and non-genomic actions.
|date=2018
|date=15.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28579120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
|full-text-url=https://sci-hub.do/10.1016/j.mce.2017.05.035
}}
}}
* {{medline-title
* {{medline-title
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|title=Targeted next generation sequencing of the entire vitamin D receptor gene reveals polymorphisms correlated with vitamin D deficiency among older Filipino women with and without fragility fracture.
|date=10.04.2018
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28068558
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2016.12.003
}}
}}
* {{medline-title
* {{medline-title
|title=Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways.
|title=Using Hyperpolarized  Xe MRI to Quantify the Pulmonary Ventilation Distribution.
|date=27.03.2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590617
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27617823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915310
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411263
}}
}}
* {{medline-title
* {{medline-title
|title=Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults.
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
|date=04.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29383869
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847877
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632
}}
}}
* {{medline-title
* {{medline-title
|title=Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation.
|title=Relationship between cardiometabolic profile, vitamin D status and BsmI polymorphism of the [[VDR]] gene in non-institutionalized elderly subjects: Cardiometabolic profile, vitamin D status and BsmI polymorphism of the [[VDR]] gene in non-institutionalized elderly subjects.
|date=03.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29220669
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27125758
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.10.007
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.04.020
}}
}}
* {{medline-title
* {{medline-title
|title=Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses.
|title=Impact of vitamin D receptor polymorphisms in centenarians.
|date=01.02.2019
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28990419
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26956844
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338564
|full-text-url=https://sci-hub.do/10.1007/s12020-016-0908-7
}}
}}
==STS==
* {{medline-title
* {{medline-title
|title=Delayed Impairment of Postural, Physical, and Muscular Functions Following Downhill Compared to Level Walking in Older People.
|title=Aging and a long-term diabetes mellitus increase expression of 1 α-hydroxylase and vitamin D receptors in the rat liver.
|date=2020
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33192547
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26471398
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609421
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.10.005
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagy displays divergent roles during intermittent amino acid starvation and toxic stress-induced senescence in cultured skeletal muscle cells.
|title=Nuclear hormone receptors: Roles of xenobiotic detoxification and sterol homeostasis in healthy aging.
|date=06.10.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33022071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26383043
|full-text-url=https://sci-hub.do/10.1002/jcp.30079
|full-text-url=https://sci-hub.do/10.3109/10409238.2015.1067186
}}
}}
* {{medline-title
* {{medline-title
|title=The WRKY53 transcription factor enhances stilbene synthesis and disease resistance by interacting with MYB14 and MYB15 in Chinese wild grape.
|title=Vitamin D Receptor Ablation and Vitamin D Deficiency Result in Reduced Grip Strength, Altered Muscle Fibers, and Increased Myostatin in Mice.
|date=30.05.2020
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32080737
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26340892
|full-text-url=https://sci-hub.do/10.1093/jxb/eraa097
|full-text-url=https://sci-hub.do/10.1007/s00223-015-0054-x
}}
}}
* {{medline-title
* {{medline-title
|title=On the role of ageing and musculoskeletal pain on dynamic balance in manual workers.
|title=Extra-intestinal calcium handling contributes to normal serum calcium levels when intestinal calcium absorption is suboptimal.
|date=02.2020
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31733466
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26319498
|full-text-url=https://sci-hub.do/10.1016/j.jelekin.2019.102374
|full-text-url=https://sci-hub.do/10.1016/j.bone.2015.08.023
}}
}}
* {{medline-title
* {{medline-title
|title=30-day mortality in frail patients undergoing cardiac surgery: the results of the [i]frailty in cardiac surgery (FICS) copenhagen study[/i].
|title=Vitamin D Receptor Genotype Modulates the Correlation between Vitamin D and Circulating Levels of let-7a/b and Vitamin D Intake in an Elderly Cohort.
|date=12.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304801
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25969372
|full-text-url=https://sci-hub.do/10.1080/14017431.2019.1644366
|full-text-url=https://sci-hub.do/10.1159/000381676
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic Fish Oil Consumption with Resistance Training Improves Grip Strength, Physical Function, and Blood Pressure in Community-Dwelling Older Adults.
|title=Vitamin D, muscle and bone: Integrating effects in development, aging and injury.
|date=09.07.2019
|date=15.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31323951
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25837735
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680896
|full-text-url=https://sci-hub.do/10.1016/j.mce.2015.03.020
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Tai Chi versus Taekkyon on balance, lower-extremity strength, and gait ability in community-dwelling older women: A single-blinded randomized clinical trial.
|title=Association between vitamin D concentration and levels of sex hormones in an elderly Polish population with different genotypes of [[VDR]] polymorphisms (rs10735810, rs1544410, rs7975232, rs731236).
|date=2020
|date=15.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282402
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25595352
|full-text-url=https://sci-hub.do/10.3233/BMR-181493
|full-text-url=https://sci-hub.do/10.1016/j.gene.2015.01.022
}}
}}
* {{medline-title
* {{medline-title
|title=Short-term starvation stress at young adult stages enhances meiotic activity of germ cells to maintain spermatogenesis in aged male Caenorhabditis elegans.
|title=Effect modification by vitamin D receptor genetic polymorphisms in the association between cumulative lead exposure and pulse pressure: a longitudinal study.
|date=06.2019
|date=13.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30816005
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25582168
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516166
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417283
}}
}}
* {{medline-title
* {{medline-title
|title=Flexibility in joint coordination remains unaffected by force and balance demands in young and old adults during simple sit-to-stand tasks.
|title=Vitamin D receptor and megalin gene polymorphisms are associated with central adiposity status and changes among US adults.
|date=02.2019
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30474739
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25191583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373350
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153078
}}
}}
* {{medline-title
* {{medline-title
|title=The influence of knee extensor fatigue on lower extremity muscle activity during chair rise in young and older adults.
|title=Vitamin D signaling in myogenesis: potential for treatment of sarcopenia.
|date=01.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30317389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25197630
|full-text-url=https://sci-hub.do/10.1007/s00421-018-3999-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147791
}}
}}
==EZH2==
* {{medline-title
* {{medline-title
|title=The sit-to-stand muscle power test: An easy, inexpensive and portable procedure to assess muscle power in older people.
|title=Linking gene expression and phenotypic changes in the developmental and evolutionary origins of osteosclerosis in the ribs of bowhead whales (Balaena mysticetus).
|date=02.10.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30179662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32729176
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.08.006
|full-text-url=https://sci-hub.do/10.1002/jez.b.22990
}}
}}
* {{medline-title
* {{medline-title
|title=Visual-Vestibular Interaction for Postural Control During Sit-to-Stand: Effects of Aging.
|title=[[EZH2]] is involved in vulnerability to neuroinflammation and depression-like behaviors induced by chronic stress in different aged mice.
|date=01.01.2019
|date=01.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008245
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32553389
|full-text-url=https://sci-hub.do/10.1123/mc.2017-0045
|full-text-url=https://sci-hub.do/10.1016/j.jad.2020.03.154
}}
}}
* {{medline-title
* {{medline-title
|title=From Intervention to Co-constitution: New Directions in Theorizing about Aging and Technology.
|title=A positive feedback loop between [[EZH2]] and NOX4 regulates nucleus pulposus cell senescence in age-related intervertebral disc degeneration.
|date=09.01.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29850812
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32025238
|full-text-url=https://sci-hub.do/10.1093/geront/gny050
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995653
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related Changes in Postural Sway During Sit-to-stand in Typical Children and Children with Cerebral Palsy.
|title=Perinatal exposure to bisphenol A impacts in the mammary gland morphology of adult Mongolian gerbils.
|date=2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29621425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917966
|full-text-url=https://sci-hub.do/10.1080/00222895.2018.1454396
|full-text-url=https://sci-hub.do/10.1016/j.yexmp.2020.104374
}}
}}
* {{medline-title
* {{medline-title
|title=Ectopic expression of Vp[[STS]]29, a stilbene synthase gene from Vitis pseudoreticulata, indicates [[STS]] presence in cytosolic oil bodies.
|title=Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing [[ABI3BP]] in gallbladder cancer cells.
|date=07.2018
|date=07.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29589146
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174563
|full-text-url=https://sci-hub.do/10.1007/s00425-018-2883-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555920
}}
* {{medline-title
|title=Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528961
|full-text-url=https://sci-hub.do/10.1519/JSC.0000000000002536
}}
}}
* {{medline-title
* {{medline-title
|title=The coordination of joint movements during sit-to-stand motion in old adults: the uncontrolled manifold analysis.
|title=Epigenetic Co-Deregulation of [[EZH2]]/[[TET1]] is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer.
|date=2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29333362
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30809307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743431
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376470
}}
}}
==FOXO1==
* {{medline-title
* {{medline-title
|title=l-Theanine attenuates liver aging by inhibiting advanced glycation end products in d-galactose-induced rats and reversing an imbalance of oxidative stress and inflammation.
|title=Improving Treatment for Myelodysplastic Syndromes Patients.
|date=03.2020
|date=25.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31899338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362079
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110823
|full-text-url=https://sci-hub.do/10.1007/s11864-018-0583-4
}}
}}
* {{medline-title
* {{medline-title
|title=Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation.
|title=Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration.
|date=2018
|date=25.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537739
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30257200
|full-text-url=https://sci-hub.do/10.1159/000495895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261459
}}
}}
* {{medline-title
* {{medline-title
|title=Functional pathways regulated by microRNA networks in CD8 T-cell aging.
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
|date=02.2019
|date=05.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30488559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351841
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005
}}
}}
* {{medline-title
* {{medline-title
|title=Introduction to FOXO Biology.
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-8900-3_1
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
}}
* {{medline-title
* {{medline-title
|title=Antioxidant modifications induced by the new metformin derivative HL156A regulate metabolic reprogramming in SAMP1/kl (-/-) mice.
|title=Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways.
|date=16.09.2018
|date=27.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222592
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590617
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188477
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915310
}}
}}
* {{medline-title
* {{medline-title
|title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls.
|title=Region specific knock-out reveals distinct roles of chromatin modifiers in adult neurogenic niches.
|date=10.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433384
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914887
}}
}}
* {{medline-title
* {{medline-title
|title=[[FOXO1]] and [[ETV6]] genes may represent novel regulators of splicing factor expression in cellular senescence.
|title=Conserved effect of aging on DNA methylation and association with [[EZH2]] polycomb protein in mice and humans.
|date=01.2019
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088951
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28249716
|full-text-url=https://sci-hub.do/10.1096/fj.201801154R
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411177
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging.
|title=The Ubiquitin-like with PHD and Ring Finger Domains 1 ([[UHRF1]])/DNA Methyltransferase 1 ([[DNMT1]]) Axis Is a Primary Regulator of Cell Senescence.
|date=25.09.2018
|date=03.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28100769
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339756
}}
}}
* {{medline-title
* {{medline-title
|title=FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration.
|title=Enhancer of Zeste Homolog 2 and Histone Deacetylase 9c Regulate Age-Dependent Mesenchymal Stem Cell Differentiation into Osteoblasts and Adipocytes.
|date=10.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963746
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27250566
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156454
|full-text-url=https://sci-hub.do/10.1002/stem.2400
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation.
|title=Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy.
|date=05.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27147278
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797
|full-text-url=https://sci-hub.do/10.1111/ejh.12771
}}
}}
* {{medline-title
* {{medline-title
|title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway.
|title=[[HBP1]]-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/[[EZH2]] Pathways and Its Impact on Cell Senescence and Tumorigenesis.
|date=2018
|date=10.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27129219
|full-text-url=https://sci-hub.do/10.1159/000487559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933444
}}
}}
* {{medline-title
* {{medline-title
|title=Role of Forkhead Box O (FOXO) transcription factor in aging and diseases.
|title=New concept: cellular senescence in pathophysiology of cholangiocarcinoma.
|date=30.03.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29428128
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26680649
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.01.051
|full-text-url=https://sci-hub.do/10.1586/17474124.2016.1133291
}}
}}
* {{medline-title
* {{medline-title
|title=FOXO in Neural Cells and Diseases of the Nervous System.
|title=[[SIRT1]] affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing.
|date=2018
|date=24.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433734
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26104761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480908
}}
}}
* {{medline-title
* {{medline-title
|title=Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium.
|title=Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus.
|date=11.12.2017
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29227245
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26004298
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724991
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2015.05.011
}}
}}
* {{medline-title
* {{medline-title
|title=FOXO Transcriptional Factors and Long-Term Living.
|title=Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes.
|date=2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25880792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574317
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623031
}}
}}
* {{medline-title
* {{medline-title
|title=Aquatide Activation of [[SIRT1]] Reduces Cellular Senescence through a [[SIRT1]]-[[FOXO1]]-Autophagy Axis.
|title=Luotonin-A based quinazolinones cause apoptosis and senescence via HDAC inhibition and activation of tumor suppressor proteins in HeLa cells.
|date=01.09.2017
|date=13.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822991
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25757092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590795
|full-text-url=https://sci-hub.do/10.1016/j.ejmech.2015.02.057
}}
}}
==HP==
==MAPT==


* {{medline-title
* {{medline-title
|title=A narrative review of highly processed food addiction across the lifespan.
|title=Association of relative brain age with tobacco smoking, alcohol consumption, and genetic variants.
|date=28.10.2020
|date=30.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33127423
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32001736
|full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2020.110152
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992742
}}
}}
* {{medline-title
* {{medline-title
|title=Beta Human Papillomavirus 8E6 Attenuates LATS Phosphorylation after Failed Cytokinesis.
|title=A blood-based nutritional risk index explains cognitive enhancement and decline in the multidomain Alzheimer prevention trial.
|date=01.06.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32238586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31921969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307087
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944714
}}
}}
* {{medline-title
* {{medline-title
|title=Cardiac baroreflex hysteresis is one of the determinants of the heart period variability asymmetry.
|title=Longitudinal associations of physical activity levels with morphological and functional changes related with aging: The [[MAPT]] study.
|date=01.10.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31365303
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31669813
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00112.2019
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110758
}}
}}
* {{medline-title
* {{medline-title
|title=Aged rats with different performances at environmental enrichment onset display different modulation of habituation and aversive memory.
|title=Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease.
|date=05.2019
|date=31.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30951838
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31673052
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2019.04.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823454
}}
}}
* {{medline-title
* {{medline-title
|title=Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation.
|title=Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective.
|date=04.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706626
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31604111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413746
|full-text-url=https://sci-hub.do/10.1016/j.pneurobio.2019.101716
}}
}}
* {{medline-title
* {{medline-title
|title=Comparison between probabilistic and Wiener-Granger causality in assessing modifications of the cardiac baroreflex control with age.
|title=Factors associated with changes of the frailty status after age 70: Findings in the [[MAPT]] study.
|date=22.10.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30207986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31005551
|full-text-url=https://sci-hub.do/10.1088/1361-6579/aae0ec
|full-text-url=https://sci-hub.do/10.1016/j.annepidem.2019.03.008
}}
}}
* {{medline-title
* {{medline-title
|title=[[CXCR3]]  CD8 T cells with naïve phenotype and high capacity for IFN-γ production are generated during homeostatic T-cell proliferation.
|title=Mitophagy and NAD inhibit Alzheimer disease.
|date=10.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30058200
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922179
|full-text-url=https://sci-hub.do/10.1002/eji.201747431
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526831
}}
}}
* {{medline-title
* {{medline-title
|title=Mapping the Proxies of Memory and Learning Function in Senior Adults with High-performing, Normal Aging and Neurocognitive Disorders.
|title=Cognitive changes of older adults with an equivocal amyloid load.
|date=2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29914037
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30689016
|full-text-url=https://sci-hub.do/10.3233/JAD-180225
|full-text-url=https://sci-hub.do/10.1007/s00415-019-09203-5
}}
}}
* {{medline-title
* {{medline-title
|title=Role of Oral Nutritional Supplements Enriched with β-Hydroxy-β-Methylbutyrate in Maintaining Muscle Function and Improving Clinical Outcomes in Various Clinical Settings.
|title=Tauopathy: A common mechanism for neurodegeneration and brain aging.
|date=2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29806855
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30668956
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984960
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377302
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of protein intake beyond habitual intakes following resistance training on cardiometabolic risk disease parameters in pre-conditioned older women.
|title=Cinnamaldehyde Improves Lifespan and Healthspan in [i]Drosophila melanogaster[/i] Models for Alzheimer's Disease.
|date=09.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29752998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228985
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136480
}}
}}
* {{medline-title
* {{medline-title
|title=Health care providers' perceptions of family caregivers' involvement in consultations within a geriatric hospital setting.
|title=Sex and age interact to determine clinicopathologic differences in Alzheimer's disease.
|date=07-08.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573893
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30219939
|full-text-url=https://sci-hub.do/10.1016/j.gerinurse.2017.12.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280837
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of age and gender on the phase and strength of the relation between heart period and systolic blood pressure spontaneous fluctuations.
|title=Effects of a 3-Year Multi-Domain Intervention with or without Omega-3 Supplementation on Cognitive Functions in Older Subjects with Increased CAIDE Dementia Scores.
|date=01.03.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29212671
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865075
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00903.2017
|full-text-url=https://sci-hub.do/10.3233/JAD-180209
}}
}}
* {{medline-title
* {{medline-title
|title=Species-specific role of gene-adjacent retroelements in human and mouse gastric carcinogenesis.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=15.04.2018
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055047
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://sci-hub.do/10.1002/ijc.31120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
* {{medline-title
* {{medline-title
|title=Associations of Helicobacter pylori infection and chronic atrophic gastritis with accelerated epigenetic ageing in older adults.
|title=Interaction between a [[MAPT]] variant causing frontotemporal dementia and mutant [[APP]] affects axonal transport.
|date=10.10.2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28898235
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29729423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998378
}}
}}
* {{medline-title
* {{medline-title
|title=Aging Does Not Affect Axon Initial Segment Structure and Somatic Localization of Tau Protein in Hippocampal Neurons of Fischer 344 Rats.
|title=Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases.
|date=07-08.2017
|date=01.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28785724
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28340083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251691
}}
}}
* {{medline-title
* {{medline-title
|title=Knee extensor power asymmetry is unrelated to functional mobility of older adults.
|title=CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of [[GRN]]/P[[GRN]].
|date=11.2017
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797826
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28189700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389672
}}
}}
==ACE2==
* {{medline-title
* {{medline-title
|title=How Does SARS-CoV-2 Affect the Central Nervous System? A Working Hypothesis.
|title=Koolen-de Vries Syndrome: Clinical Report of an Adult and Literature Review.
|date=2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27852077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701095
|full-text-url=https://sci-hub.do/10.1159/000452724
}}
}}
* {{medline-title
* {{medline-title
|title=Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2.
|title=Presymptomatic cognitive decline in familial frontotemporal dementia: A longitudinal study.
|date=2020
|date=26.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33112891
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27358337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592753
|full-text-url=https://sci-hub.do/10.1212/WNL.0000000000002895
}}
}}
* {{medline-title
* {{medline-title
|title=A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures.
|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.
|date=10.2020
|date=24.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32854108
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2708-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225
}}
}}
* {{medline-title
* {{medline-title
|title=COVID-19 and Senotherapeutics: Any Role for the Naturally-occurring Dipeptide Carnosine?
|title=Cellular and molecular modifier pathways in tauopathies: the big picture from screening invertebrate models.
|date=07.2020
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32765939
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26756400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390525
|full-text-url=https://sci-hub.do/10.1111/jnc.13532
}}
}}
* {{medline-title
* {{medline-title
|title=The dual impact of [[ACE2]] in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions.
|title=Drosophila models of Alzheimer's disease: advances, limits, and perspectives.
|date=15.09.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32653522
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25697708
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347488
|full-text-url=https://sci-hub.do/10.3233/JAD-142802
}}
}}
* {{medline-title
* {{medline-title
|title=The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of "inflame-aging".
|title=Association between [[MAPT]] haplotype and memory function in patients with Parkinson's disease and healthy aging individuals.
|date=09.2020
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32529477
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25577413
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289226
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353560
}}
}}
==MBP==
* {{medline-title
* {{medline-title
|title=Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis.
|title=Demyelination associated with chronic arsenic exposure in Wistar rats.
|date=01.08.2020
|date=15.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32510973
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32171569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381712
|full-text-url=https://sci-hub.do/10.1016/j.taap.2020.114955
}}
* {{medline-title
|title=Natural killer cells as participants in pathogenesis of rat experimental autoimmune encephalomyelitis (EAE): lessons from research on rats with distinct age and strain.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32140045
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050050
}}
}}
* {{medline-title
* {{medline-title
|title=A Mouse Model of SARS-CoV-2 Infection and Pathogenesis.
|title=Whey protein concentrate supplementation protects rat brain against aging-induced oxidative stress and neurodegeneration.
|date=08.07.2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32485164
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29199432
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250783
|full-text-url=https://sci-hub.do/10.1139/apnm-2017-0578
}}
}}
* {{medline-title
* {{medline-title
|title=COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches.
|title=Strain specificities in age-related changes in mechanisms promoting and controlling rat spinal cord damage in experimental autoimmune encephalomyelitis.
|date=08.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32430627
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29128575
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237344
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.002
}}
}}
* {{medline-title
* {{medline-title
|title=Gut microbiota and Covid-19- possible link and implications.
|title=Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils.
|date=08.2020
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32430279
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29046699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645602
}}
}}
* {{medline-title
* {{medline-title
|title=Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes.
|title=Schwann Cell Phenotype Changes in Aging Human Dental Pulp.
|date=06.2020
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32389499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28972819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252014
|full-text-url=https://sci-hub.do/10.1177/0022034517733967
}}
}}
* {{medline-title
* {{medline-title
|title=Restoration of the Renin-Angiotensin System Balance Is a Part of the Effect of Fasting on Cardiovascular Rejuvenation: Role of Age and Fasting Models.
|title=Blood pressure reactivity to mental stress is attenuated following resistance exercise in older hypertensive women.
|date=08.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31571520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28553088
|full-text-url=https://sci-hub.do/10.1089/rej.2019.2254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439937
}}
}}
* {{medline-title
* {{medline-title
|title=Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in [[ACE2]]-knockout mice.
|title=Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss.
|date=30.09.2019
|date=08.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31519791
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28482862
|full-text-url=https://sci-hub.do/10.1042/CS20190573
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421332
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study.
|title=Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for [[CA1]] neurons.
|date=14.05.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089908
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28212893
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517452
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388507
}}
}}
* {{medline-title
* {{medline-title
|title=The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system.
|title=Postnatal alteration of monocarboxylate transporter 1 expression in the rat corpus callosum.
|date=03.2018
|date=04.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407880
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27982679
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2018.01.043
|full-text-url=https://sci-hub.do/10.33549/physiolres.933365
}}
}}
==APC==
* {{medline-title
* {{medline-title
|title=Differences between blacks and whites in well-being, beliefs, emotional states, behaviors and survival, 1978-2014.
|title=Bowel Preparation Is Associated with Reduced Morbidity in Elderly Patients Undergoing Elective Colectomy.
|date=2020
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32925952
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27896654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489510
|full-text-url=https://sci-hub.do/10.1007/s11605-016-3314-9
}}
}}
* {{medline-title
* {{medline-title
|title=Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging.
|title=Myelin Basic Protein Regulates Primitive and Definitive Neural Stem Cell Proliferation from the Adult Spinal Cord.
|date=07.08.2020
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32771388
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27573615
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672319
|full-text-url=https://sci-hub.do/10.1002/stem.2488
}}
* {{medline-title
|title=Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?
|date=12.08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27519525
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983062
}}
}}
* {{medline-title
* {{medline-title
|title=Burden of musculoskeletal disorders in Iran during 1990-2017: estimates from the Global Burden of Disease Study 2017.
|title=Generation of a LacZ reporter transgenic mouse line for the stereological analysis of oligodendrocyte loss in galactosylceramidase deficiency.
|date=10.07.2020
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32651719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27426866
|full-text-url=https://sci-hub.do/10.1007/s11657-020-00767-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069144
}}
}}
* {{medline-title
* {{medline-title
|title=Fall-related mortality trends in older Japanese adults aged ≥65 years: a nationwide observational study.
|title=Loss of Hippocampal Oligodendrocytes Contributes to the Deficit of Contextual Fear Learning in Adult Rats Experiencing Early Bisphenol A Exposure.
|date=11.12.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31831549
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27364615
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924807
|full-text-url=https://sci-hub.do/10.1007/s12035-016-0003-3
}}
}}
* {{medline-title
* {{medline-title
|title=Stroke Mortality Rates and Trends in Romania, 1994-2017.
|title=Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4  T cells in aged rats.
|date=12.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31624036
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448779
|full-text-url=https://sci-hub.do/10.1016/j.jstrokecerebrovasdis.2019.104431
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596406
}}
}}
* {{medline-title
* {{medline-title
|title=A new approach to quantifying the EEG during walking: Initial evidence of gait related potentials and their changes with aging and dual tasking.
|title=Sleeve Gastrectomy Decreases Body Weight, Whole-Body Adiposity, and Blood Pressure Even in Aged Diet-Induced Obese Rats.
|date=15.10.2019
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31449852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26439733
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110709
|full-text-url=https://sci-hub.do/10.1007/s11695-015-1919-9
}}
}}
* {{medline-title
* {{medline-title
|title=Risk-period-cohort approach for averting identification problems in longitudinal models.
|title=Classic and Golli Myelin Basic Protein have distinct developmental trajectories in human visual cortex.
|date=2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31291339
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25964736
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408849
}}
}}
* {{medline-title
* {{medline-title
|title=Wnt Signaling Mediates the Aging-Induced Differentiation Impairment of Intestinal Stem Cells.
|title=Defective renal dopamine function and sodium-sensitive hypertension in adult ovariectomized Wistar rats: role of the cytochrome P-450 pathway.
|date=06.2019
|date=15.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790135
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25925257
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534527
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00450.2014
}}
}}
* {{medline-title
* {{medline-title
|title=Biased estimation of trends in cohort effects: the problems with age-period-cohort models in ecology.
|title=White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke.
|date=12.2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30347112
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25836044
|full-text-url=https://sci-hub.do/10.1002/ecy.2545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591088
}}
}}
* {{medline-title
* {{medline-title
|title=[Gender Differences in Projected Life Expectancy in Japan (2023-2047) Determined by Bayesian Age-Period-Cohort Analysis].
|title=Age-related changes in spleen of Dark Agouti rats immunized for experimental autoimmune encephalomyelitis.
|date=2018
|date=15.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270302
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25595261
|full-text-url=https://sci-hub.do/10.1265/jjh.73.338
|full-text-url=https://sci-hub.do/10.1016/j.jneuroim.2014.12.014
}}
}}
* {{medline-title
* {{medline-title
|title=Activated Yes-Associated Protein Accelerates Cell Cycle, Inhibits Apoptosis, and Delays Senescence in Human Periodontal Ligament Stem Cells.
|title=Phase separation of myelin sheath in Triton X-114 solution: predominant localization of the 21.5-kDa isoform of myelin basic protein in the lipid raft-associated domain.
|date=2018
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30123063
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24459152
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097269
|full-text-url=https://sci-hub.do/10.1093/jb/mvu005
}}
}}
==PAH==
* {{medline-title
* {{medline-title
|title=Activating the Anaphase Promoting Complex to Enhance Genomic Stability and Prolong Lifespan.
|title=Changes in light absorption by brown carbon in soot particles due to heterogeneous ozone aging in a smog chamber.
|date=27.06.2018
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29954095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32771846
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073722
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2020.115273
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04.
|title=Factors associated with pulmonary arterial hypertension ([[PAH]]) in systemic sclerosis (SSc).
|date=2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29675370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659476
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902356
|full-text-url=https://sci-hub.do/10.1016/j.autrev.2020.102602
}}
}}
* {{medline-title
* {{medline-title
|title=[Role and alterations of DNA methylation during the aging and cancer].
|title=Potentially Avoidable Hospitalization among Long-Term Care Insurance Beneficiaries with Dementia.
|date=01.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32316707
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509129
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA-210-mediated proliferation, survival, and angiogenesis promote cardiac repair post myocardial infarction in rodents.
|title=Burden of disease at the same limit of exposure to airborne polycyclic aromatic hydrocarbons varies significantly across countries depending on the gap in longevity.
|date=12.2017
|date=30.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948298
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31108419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941944
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2019.04.028
}}
}}
==CD44==
* {{medline-title
* {{medline-title
|title=Hyaluronan goes to great length.
|title=Converging Paths of Pulmonary Arterial Hypertension and Cellular Senescence.
|date=17.07.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32908962
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30758225
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453635
|full-text-url=https://sci-hub.do/10.1165/rcmb.2018-0329TR
}}
}}
* {{medline-title
* {{medline-title
|title=Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties.
|title=Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in [[CYP1A1]]-overexpressing breast cancer cells.
|date=12.05.2020
|date=15.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32398747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217962
|full-text-url=https://sci-hub.do/10.1016/j.bmc.2018.11.013
}}
}}
* {{medline-title
* {{medline-title
|title=Maturity-dependent cartilage cell plasticity and sensitivity to external perturbation.
|title=Exposure to Polycyclic Aromatic Hydrocarbons and Accelerated DNA Methylation Aging.
|date=06.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32321631
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29906262
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2020.103732
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108582
}}
}}
* {{medline-title
* {{medline-title
|title=Aged Mice Exhibit Severe Exacerbations of Dry Eye Disease with an Amplified Memory Th17 Cell Response.
|title=Arrhythmias in adult patients with congenital heart disease and pulmonary arterial hypertension.
|date=07.2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32289288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29776964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369573
|full-text-url=https://sci-hub.do/10.1136/heartjnl-2017-312881
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice.
|title=Reduced bioavailability and plant uptake of polycyclic aromatic hydrocarbons from soil slurry amended with biochars pyrolyzed under various temperatures.
|date=13.02.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32054990
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29627960
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018741
|full-text-url=https://sci-hub.do/10.1007/s11356-018-1874-9
}}
}}
* {{medline-title
* {{medline-title
|title=Defective induction of the proteasome associated with T-cell receptor signaling underlies T-cell senescence.
|title=Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice.
|date=12.2019
|date=14.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31621149
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540228
|full-text-url=https://sci-hub.do/10.1111/gtc.12728
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851307
}}
}}
* {{medline-title
* {{medline-title
|title=[[CD44]]v8-10 and [[CD44]]s Are Age-dependently Expressed in Primary Cultured Papillary Thyroid Carcinoma Cells and Are Associated with Cell Proliferation.
|title=Changes of total and freely dissolved polycyclic aromatic hydrocarbons and toxicity of biochars treated with various aging processes.
|date=25.04.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31341151
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29474988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668591
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2018.01.073
}}
}}
* {{medline-title
* {{medline-title
|title=Immunophenotypic characterization, multi-lineage differentiation and aging of zebrafish heart and liver tissue-derived mesenchymal stem cells as a novel approach in stem cell-based therapy.
|title=Bioaccessibility of [[PAH]]s and [[PAH]] derivatives in a fuel soot assessed by an in vitro digestive model with absorptive sink: Effects of aging the soot in a soil-water mixture.
|date=04.2019
|date=15.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30947959
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28968578
|full-text-url=https://sci-hub.do/10.1016/j.tice.2019.01.006
|full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2017.09.227
}}
}}
* {{medline-title
* {{medline-title
|title=CD8 , but not [[CD4]]  effector/memory T cells, express the [[[[CD4]]4]] [[CD4]]5RB  phenotype with aging, which displays reduced expression levels of P2X  receptor and ATP-induced cellular responses.
|title=Airborne polycyclic aromatic hydrocarbons trigger human skin cells aging through aryl hydrocarbon receptor.
|date=03.2019
|date=01.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30383448
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28526404
|full-text-url=https://sci-hub.do/10.1096/fj.201800867R
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.04.160
}}
}}
* {{medline-title
* {{medline-title
|title=Regenerative potential of human nucleus pulposus resident stem/progenitor cells declines with ageing and intervertebral disc degeneration.
|title=DNA integrity-protecting and survival-promoting activity of serotonergic system in sturgeon juveniles and sazans.
|date=10.2018
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30015833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28321525
|full-text-url=https://sci-hub.do/10.3892/ijmm.2018.3766
|full-text-url=https://sci-hub.do/10.1007/s10695-017-0360-5
}}
}}
* {{medline-title
* {{medline-title
|title=Multi-color flow cytometry for evaluating age-related changes in memory lymphocyte subsets in dogs.
|title=Disruption of phenylalanine hydroxylase reduces adult lifespan and fecundity, and impairs embryonic development in parthenogenetic pea aphids.
|date=10.2018
|date=03.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29859828
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27694983
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046115
}}
}}
* {{medline-title
* {{medline-title
|title=Therapeutic efficacy of olfactory stem cells in rotenone induced Parkinsonism in adult male albino rats.
|title=Hepatic Responses of Juvenile Fundulus heteroclitus from Pollution-adapted and Nonadapted Populations Exposed to Elizabeth River Sediment Extract.
|date=07.2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29864896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26992886
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.04.160
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912431
}}
}}
* {{medline-title
* {{medline-title
|title=Precise Intradermal Injection of Nanofat-Derived Stromal Cells Combined with Platelet-Rich Fibrin Improves the Efficacy of Facial Skin Rejuvenation.
|title=Non-muscle myosin light chain promotes endothelial progenitor cells senescence and dysfunction in pulmonary hypertensive rats through up-regulation of NADPH oxidase.
|date=2018
|date=15.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768259
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26872992
|full-text-url=https://sci-hub.do/10.1159/000489809
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2016.02.022
}}
}}
* {{medline-title
* {{medline-title
|title=Some chemotherapeutics-treated colon cancer cells display a specific phenotype being a combination of stem-like and senescent cell features.
|title=Maintaining lung health with longstanding HIV.
|date=02.01.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053388
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26555039
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689652
}}
}}
* {{medline-title
* {{medline-title
|title=A Trickster in Disguise: Hyaluronan's Ambivalent Roles in the Matrix.
|title=Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.
|date=2017
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29062810
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26076038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496295
}}
}}
==CORT==
* {{medline-title
* {{medline-title
|title=Sex differences in body composition, metabolism-related hormones, and energy homeostasis during aging in Wistar rats.
|title=Pulmonary arterial hypertension in rats due to age-related arginase activation in intermittent hypoxia.
|date=10.2020
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33075214
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25490411
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571994
|full-text-url=https://sci-hub.do/10.1165/rcmb.2014-0163OC
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of age and social isolation on murine hippocampal biochemistry and behavior.
|title=Symptom Prevalence, Symptom Severity, and Health-Related Quality of Life Among Young, Middle, and Older Adults With Pulmonary Arterial Hypertension.
|date=10.2020
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32866520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25294227
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111337
|full-text-url=https://sci-hub.do/10.1177/1049909114554079
}}
}}
* {{medline-title
* {{medline-title
|title=Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice.
|title=Plasma concentrations of tadalafil in children with pulmonary arterial hypertension.
|date=10.2020
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32669383
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24872209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529050
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000055
}}
}}
==TST==
* {{medline-title
* {{medline-title
|title=Sex- and age-dependent differences in the hormone and drinking responses to water deprivation.
|title=H S Donors Reverse Age-Related Gastric Malfunction Impaired Due to Fructose-Induced Injury [i]via[/i] CBS, CSE, and [[TST]] Expression.
|date=01.03.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31967852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32848752
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00303.2019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396573
}}
}}
* {{medline-title
* {{medline-title
|title=Ontogeny of the adrenocortical response in an extremely altricial bird.
|title=Adaptations in mechanical muscle function, muscle morphology, and aerobic power to high-intensity endurance training combined with either traditional or power strength training in older adults: a randomized clinical trial.
|date=12.2019
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32239311
|full-text-url=https://sci-hub.do/10.1002/jez.2317
|full-text-url=https://sci-hub.do/10.1007/s00421-020-04355-z
}}
}}
* {{medline-title
* {{medline-title
|title=Exposure to jet lag aggravates depression-like behaviors and age-related phenotypes in rats subject to chronic corticosterone.
|title=Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging.
|date=05.08.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31314053
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31602410
|full-text-url=https://sci-hub.do/10.1093/abbs/gmz070
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778117
}}
}}
* {{medline-title
* {{medline-title
|title=Hyperadrenocorticism of calorie restriction contributes to its anti-inflammatory action in mice.
|title=Objective Sleep Duration in Older Adults: Results From The Irish Longitudinal Study on Ageing.
|date=06.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30938024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31579942
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516174
|full-text-url=https://sci-hub.do/10.1111/jgs.16177
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of chronic corticosterone-induced depression on circadian rhythms and age-related phenotypes in mice.
|title=Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis.
|date=01.12.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30395149
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31312133
|full-text-url=https://sci-hub.do/10.1093/abbs/gmy132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614445
}}
}}
* {{medline-title
* {{medline-title
|title=Early Life Stress Strengthens Trait Covariance: A Plastic Response That Results in Reduced Flexibility.
|title=Validity Evaluation of the Fitbit Charge2 and the Garmin vivosmart HR  in Free-Living Environments in an Older Adult Cohort.
|date=11.2018
|date=19.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30332583
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219048
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414225
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607774
}}
}}
* {{medline-title
* {{medline-title
|title=Both Basal and Acute Restraint Stress-Induced c-Fos Expression Is Influenced by Age in the Extended Amygdala and Brainstem Stress Centers in Male Rats.
|title=Paradoxical effect of testosterone supplementation therapy on cardiac ischemia/reperfusion injury in aged rats.
|date=2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30186150
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113579
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.012
}}
}}
* {{medline-title
* {{medline-title
|title=Stress-induced corticosterone secretion covaries with working memory in aging.
|title=Sleep Disturbances and Risk of Hospitalization and Inpatient Days Among Older Women.
|date=11.2018
|date=01.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30144648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28329356
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162104
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804992
}}
}}
* {{medline-title
* {{medline-title
|title=Sex-specific differences in corticosterone secretion, behavioral phenotypes and expression of TrkB.T1 and TrkB.FL receptor isoforms: Impact of systemic TrkB inhibition and combinatory stress exposure in adolescence.
|title=Relationships between [i]FTO[/i] rs9939609, [i]MC4R[/i] rs17782313, and [i]PPARγ[/i] rs1801282 polymorphisms and the occurrence of selected metabolic and hormonal disorders in middle-aged and elderly men - a preliminary study.
|date=30.08.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29753050
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27920511
|full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2018.05.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126003
}}
}}
* {{medline-title
* {{medline-title
|title=Lifelong Aerobic Exercise Reduces the Stress Response in Rats.
|title=Rest-Activity Patterns in Older Adults with Heart Failure and Healthy Older Adults.
|date=15.04.2018
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462703
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27402684
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.02.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467285
}}
}}
* {{medline-title
* {{medline-title
|title=sst -receptor gene deletion exacerbates chronic stress-induced deficits: Consequences for emotional and cognitive ageing.
|title=The impact of BCG vaccination on tuberculin skin test responses in children is age dependent: evidence to be considered when screening children for tuberculosis infection.
|date=30.08.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29409919
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27335104
|full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2018.01.022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036222
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic corticosterone-induced depression mediates premature aging in rats.
|title=The relation between polysomnography and subjective sleep and its dependence on age - poor sleep may become good sleep.
|date=15.03.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29329057
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27122391
|full-text-url=https://sci-hub.do/10.1016/j.jad.2017.12.073
|full-text-url=https://sci-hub.do/10.1111/jsr.12407
}}
}}
==DDT==
* {{medline-title
* {{medline-title
|title=Prognostic Value of a Test of Central Auditory Function in Conversion from Mild Cognitive Impairment to Dementia.
|title=Association between physiological falls risk and physical performance tests among community-dwelling older adults.
|date=2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32388503
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26316727
|full-text-url=https://sci-hub.do/10.1159/000506621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541555
}}
}}
* {{medline-title
* {{medline-title
|title=Uptake kinetics of four hydrophobic organic pollutants in the earthworm Eisenia andrei in aged laboratory-contaminated natural soils.
|title=Anthropometric reference data for elderly Swedes and its disease-related pattern.
|date=01.04.2020
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061977
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25990690
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2020.110317
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559758
}}
}}
* {{medline-title
* {{medline-title
|title=Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish.
|title=Impact of maternal melatonin suppression on forced swim and tail suspension behavioral despair tests in adult offspring.
|date=03-04.2020
|date=04-06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31911208
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25866579
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061078
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392102
}}
}}
* {{medline-title
* {{medline-title
|title=Second generation effects of larval metal pollutant exposure on reproduction, longevity and insecticide tolerance in the major malaria vector Anopheles arabiensis (Diptera: Culicidae).
|title=Controversies in testosterone supplementation therapy.
|date=07.01.2020
|date=03-04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31910892
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25652639
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650474
}}
}}
* {{medline-title
* {{medline-title
|title=Protective effect of Pedro-Ximénez must against p,p'-DDE-induced liver damages in aged Mus spretus mice.
|title=Diagnosis and management of testosterone deficiency.
|date=02.2020
|date=03-04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765701
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25532575
|full-text-url=https://sci-hub.do/10.1016/j.fct.2019.110984
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650468
}}
}}
* {{medline-title
* {{medline-title
|title=Low-dose endosulfan inhibits proliferation and induces senescence and pro-inflammatory cytokine production in human lymphocytes, preferentially impacting cytotoxic cells.
|title=Testosterone replacement therapy: who to evaluate, what to use, how to follow, and who is at risk?
|date=12.2019
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589084
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25485919
|full-text-url=https://sci-hub.do/10.1080/1547691X.2019.1668513
|full-text-url=https://sci-hub.do/10.3810/hp.2014.12.1160
}}
}}
* {{medline-title
* {{medline-title
|title=DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy.
|title=An Overview of Testosterone Therapy.
|date=22.08.2019
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251805
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25398416
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698745
|full-text-url=https://sci-hub.do/10.1177/1557988314556671
}}
}}
* {{medline-title
* {{medline-title
|title=The contribution of gut bacteria to insecticide resistance and the life histories of the major malaria vector Anopheles arabiensis (Diptera: Culicidae).
|title=Associations of objectively and subjectively measured sleep quality with subsequent cognitive decline in older community-dwelling men: the MrOS sleep study.
|date=24.06.2019
|date=01.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31235803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24899757
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591418
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044750
}}
}}
* {{medline-title
* {{medline-title
|title=Exposure to the insecticide-treated bednet PermaNet 2.0 reduces the longevity of the wild African malaria vector Anopheles funestus but GSTe2-resistant mosquitoes live longer.
|title=Chronotype, bed timing and total sleep time in seniors.
|date=2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30870507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24517139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088929
}}
}}
* {{medline-title
* {{medline-title
|title=The occurrence and dynamics of polychlorinated hydrocarbons in roe deer ([i]Capreolus capreolus[/i]) in South-western Slovakia.
|title=Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus.
|date=2019
|date=01.01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30729857
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24470704
|full-text-url=https://sci-hub.do/10.1080/10934529.2019.1574152
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902878
}}
}}
==BAX==
* {{medline-title
* {{medline-title
|title=Insecticide resistance status of three vectors of Japanese encephalitis in east central India.
|title=Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-X  -[[BAX]] interaction.
|date=06.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30565276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32652830
|full-text-url=https://sci-hub.do/10.1111/mve.12352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530780
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of aging on bioaccessibility of [[DDT]]s and PCBs in marine sediment.
|title=CREB Signaling Mediates Dose-Dependent Radiation Response in the Murine Hippocampus Two Years after Total Body Exposure.
|date=02.2019
|date=03.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30471469
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31657930
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349416
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00552
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of commercial herbicide exposure on the life history and insecticide resistance phenotypes of the major malaria vector Anopheles arabiensis (Diptera: culicidae).
|title=Reduced sucrose nonfermenting AMPK-related kinase (SNARK) activity aggravates cancer-induced skeletal muscle wasting.
|date=12.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30179608
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31387190
|full-text-url=https://sci-hub.do/10.1016/j.actatropica.2018.08.030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686878
}}
}}
* {{medline-title
* {{medline-title
|title=Is Chronic Exposure to Low-Dose Organochlorine Pesticides a New Risk Factor of T-cell Immunosenescence?
|title=Modulated electro-hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro.
|date=10.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991517
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31183995
|full-text-url=https://sci-hub.do/10.1158/1055-9965.EPI-17-0799
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675742
}}
}}
* {{medline-title
* {{medline-title
|title=The influence of age on insecticide susceptibility of Anopheles arabiensis during dry and rainy seasons in rice irrigation schemes of Northern Tanzania.
|title=The Clearance Effect of Tetrahedral DNA Nanostructures on Senescent Human Dermal Fibroblasts.
|date=11.09.2017
|date=16.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28893240
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30562007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594483
|full-text-url=https://sci-hub.do/10.1021/acsami.8b20530
}}
}}
==GDF15==
* {{medline-title
* {{medline-title
|title=Disease-specific plasma levels of mitokines FGF21, [[GDF15]], and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging.
|title=Premature placental aging in term small-for-gestational-age and growth-restricted fetuses.
|date=31.10.2020
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33131010
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125412
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00287-w
|full-text-url=https://sci-hub.do/10.1002/uog.20103
}}
}}
* {{medline-title
* {{medline-title
|title=Growth differentiation factor 15 protects against the aging-mediated systemic inflammatory response in humans and mice.
|title=Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training.
|date=08.2020
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32691494
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030137
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431835
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.011
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of Epigenetic Age Predictors in Pain-Related Conditions.
|title=Xanthohumol exerts protective effects in liver alterations associated with aging.
|date=2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32582603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29536163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296181
|full-text-url=https://sci-hub.do/10.1007/s00394-018-1657-6
}}
}}
* {{medline-title
* {{medline-title
|title=[[GDF15]] Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness.
|title=Protective effect of xanthohumol against age-related brain damage.
|date=2020
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32477368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235447
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011
}}
}}
* {{medline-title
* {{medline-title
|title=[[GDF15]] is an epithelial-derived biomarker of idiopathic pulmonary fibrosis.
|title=[Inula Britannica flower total flavonoids reduces the apoptosis of aging bone marrow mesenchymal stem cells by anti-oxidation].
|date=01.10.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31432710
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28502304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842909
 
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence-associated tissue microenvironment promotes colon cancer formation through the secretory factor [[GDF15]].
|title=Hilar granule cells of the mouse dentate gyrus: effects of age, septotemporal location, strain, and selective deletion of the proapoptotic gene [[BAX]].
|date=12.2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31389184
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28314928
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601016
}}
}}
* {{medline-title
* {{medline-title
|title=mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism.
|title=p16  enhances the transcriptional and the apoptotic functions of p53 through DNA-dependent interaction.
|date=06.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30924297
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28218424
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516169
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266037
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis.
|date=08.2019
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889579
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2016.11.007
}}
}}
* {{medline-title
* {{medline-title
|title=Growth differentiation factor 15 ([[GDF15]]): A survival protein with therapeutic potential in metabolic diseases.
|title=Mechanisms of Heshouwuyin in regulating apoptosis of testicular cells in aging rats through mitochondrial pathway.
|date=06.2019
|date=01.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790643
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27586689
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196666
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009692
}}
}}
* {{medline-title
* {{medline-title
|title=[The role of «Youth and aging proteins» in essential hypertension pathogenesis.]
|title=Response of [[BAX]], Bcl-2 Proteins, and [[SIRT1]]/[[PGC]]-1α mRNA Expression to 8-Week Treadmill Running in the Aging Rat Skeletal Muscle.
|date=2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30584875
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27526155
 
|full-text-url=https://sci-hub.do/10.1007/978-3-319-38810-6_38
}}
}}
* {{medline-title
* {{medline-title
|title=A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup.
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|date=12.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30151729
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294728
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
}}
}}
* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Apoptosis in young and old denervated rat skeletal muscle.
|date=11.2018
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27312511
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://sci-hub.do/10.1002/mus.25221
}}
* {{medline-title
|title=Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27260470
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2016.03.008
}}
}}
* {{medline-title
* {{medline-title
|title=Plasma proteomic signature of age in healthy humans.
|title=Melatonin decreases the expression of inflammation and apoptosis markers in the lung of a senescence-accelerated mice model.
|date=10.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29992704
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26656745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156492
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.11.021
}}
}}
* {{medline-title
* {{medline-title
|title=Human Aging and Longevity Are Characterized by High Levels of Mitokines.
|title=Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats.
|date=23.04.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26594596
|full-text-url=https://sci-hub.do/10.1093/gerona/gly153
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642830
}}
}}
* {{medline-title
* {{medline-title
|title=Induction of Growth Differentiation Factor 15 in Skeletal Muscle of Old Taurine Transporter Knockout Mouse.
|title=The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats.
|date=2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29491220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25910621
|full-text-url=https://sci-hub.do/10.1248/bpb.b17-00969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854160
}}
}}
==LRRK2==
==CCR2==


* {{medline-title
* {{medline-title
|title=Accelerated telomere shortening independent of [[LRRK2]] variants in Chinese patients with Parkinson's disease.
|title=Hip Fracture Leads to Transitory Immune Imprint in Older Patients.
|date=29.10.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33122450
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33072114
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655166
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533556
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of [[LRRK2]] loss-of-function variants in humans.
|title=The CC-chemokine receptor 2 is involved in the control of ovarian folliculogenesis and fertility lifespan in mice.
|date=06.2020
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32461697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32615332
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303015
|full-text-url=https://sci-hub.do/10.1016/j.jri.2020.103174
}}
}}
* {{medline-title
* {{medline-title
|title=Parkinson's disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging.
|title=Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity.
|date=19.02.2020
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32075681
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32543720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031993
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704037
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagy and [[LRRK2]] in the Aging Brain.
|title=Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction.
|date=2019
|date=26.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920513
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32154790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928047
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213793
}}
}}
* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by [[CCR2]].
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
* {{medline-title
|title=Age-dependent accumulation of oligomeric [[SNCA]]/α-synuclein from impaired degradation in mutant [[LRRK2]] knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
|date=02.2020
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013280
}}
}}
* {{medline-title
* {{medline-title
|title=A Neuron-Glial Trans-Signaling Cascade Mediates [[LRRK2]]-Induced Neurodegeneration.
|title=Klotho-mediated targeting of CCL2 suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments.
|date=12.02.2019
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30759389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545552
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474846
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822285
}}
}}
* {{medline-title
* {{medline-title
|title=Upregulation of the p53-p21 pathway by G2019S [[LRRK2]] contributes to the cellular senescence and accumulation of α-synuclein.
|title=Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90   subset.
|date=02.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712480
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31353772
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422450
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718537
}}
}}
* {{medline-title
* {{medline-title
|title=G2019S [[LRRK2]] mutation facilitates α-synuclein neuropathology in aged mice.
|title=Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells.
|date=12.2018
|date=14.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30172844
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429354
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2018.08.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445267
}}
}}
* {{medline-title
* {{medline-title
|title=The Enzymatic Core of the Parkinson's Disease-Associated Protein [[LRRK2]] Impairs Mitochondrial Biogenesis in Aging Yeast.
|title=Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain.
|date=2018
|date=30.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29977190
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29848996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032263
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related pathology after adenoviral overexpression of the leucine-rich repeat kinase 2 in the mouse striatum.
|title=Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging.
|date=06.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29550548
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624852
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.02.008
|full-text-url=https://sci-hub.do/10.1002/cyto.a.23372
}}
}}
* {{medline-title
* {{medline-title
|title=[[LRRK2]] G2019S Induces Anxiety/Depression-like Behavior before the Onset of Motor Dysfunction with 5-HT  Receptor Upregulation in Mice.
|title=Inhibition of Radiation-Induced Ccl2 Signaling Protects Lungs from Vascular Dysfunction and Endothelial Cell Loss.
|date=14.02.2018
|date=10.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29305532
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705874
|full-text-url=https://sci-hub.do/10.1089/ars.2017.7458
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.
|title=Attenuated Macrophage Infiltration in Glomeruli of Aged Mice Resulting in Ameliorated Kidney Injury in Nephrotoxic Serum Nephritis.
|date=15.11.2017
|date=10.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29056298
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415117
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693787
|full-text-url=https://sci-hub.do/10.1093/gerona/gly019
}}
}}
* {{medline-title
* {{medline-title
|title=Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in [[LRRK2]] G2019S knock-in mice.
|title=Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression.
|date=20.09.2017
|date=10.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28930069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27728804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633343
|full-text-url=https://sci-hub.do/10.1016/j.ccell.2016.09.003
}}
}}
* {{medline-title
* {{medline-title
|title=Suppression of neuroinflammation by matrix metalloproteinase-8 inhibitor in aged normal and [[LRRK2]] G2019S Parkinson's disease model mice challenged with lipopolysaccharide.
|title=Absence of [[CCR2]] results in an inflammaging environment in young mice with age-independent impairments in muscle regeneration.
|date=18.11.2017
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28958936
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27531927
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.129
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069084
}}
}}
==MET==
* {{medline-title
* {{medline-title
|title=Self-rated health in relation to fruit and vegetable consumption and physical activity among older cancer survivors.
|title=Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities.
|date=26.09.2020
|date=13.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32979089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27292029
|full-text-url=https://sci-hub.do/10.1007/s00520-020-05782-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910019
}}
}}
* {{medline-title
* {{medline-title
|title=Leisure-time physical activity volume, intensity, and duration from mid- to late-life in U.S. subpopulations by race and sex. The Atherosclerosis Risk In Communities (ARIC) Study.
|title=Age exacerbates the [[CCR2]]/5-mediated neuroinflammatory response to traumatic brain injury.
|date=13.03.2020
|date=18.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32170049
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27090212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835854
}}
}}
* {{medline-title
* {{medline-title
|title=Repressive H3K9me2 protects lifespan against the transgenerational burden of COMPASS activity in [i]C. elegans[/i].
|title=Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging.
|date=09.12.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31815663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26973110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7299346
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.12.019
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of Anthropometrics on Step-Rate Thresholds for Moderate and Vigorous Physical Activity in Older Adults: Scientific Modeling Study.
|title=Alterations in Monocyte Phenotypes and Functions after a Hip Fracture in Elderly Individuals: A 6-Month Longitudinal Study.
|date=13.12.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31518246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26812523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715008
|full-text-url=https://sci-hub.do/10.1159/000443142
}}
}}
* {{medline-title
* {{medline-title
|title=Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study.
|title=[[TNF]] Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity.
|date=12.06.2019
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31186007
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26766566
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713203
}}
}}
* {{medline-title
* {{medline-title
|title=Metformin prevents murine ovarian aging.
|title=Senescent dermal fibroblasts enhance stem cell migration through [[CCL2]]/C[[CR2]] axis.
|date=10.06.2019
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182682
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25808810
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594816
|full-text-url=https://sci-hub.do/10.1111/exd.12701
}}
}}
* {{medline-title
* {{medline-title
|title=Afterword: Oral Methioninase-Answer to Cancer and Fountain of Youth?
|title=Differential expression of monocyte surface markers among TB patients with diabetes co-morbidity.
|date=2019
|date=12.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30725426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24388654
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-8796-2_24
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028445
}}
}}
==CD40==
* {{medline-title
* {{medline-title
|title=Leveraging Household Structure for Increasing Adult Physical Activity in a Low-Income, African American Community.
|title=The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy.
|date=07.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30486674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30560130
|full-text-url=https://sci-hub.do/10.1177/1524839918814731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287204
}}
}}
* {{medline-title
* {{medline-title
|title=Appropriate Amount of Regular Exercise Is Associated with a Reduced Mortality Risk.
|title=Age-Related Changes on [[CD40]] Promotor Methylation and Immune Gene Expressions in Thymus of Chicken.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30519246
|full-text-url=https://sci-hub.do/10.1249/MSS.0000000000001734
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259354
}}
}}
* {{medline-title
* {{medline-title
|title=The Relationship between Cardiorespiratory Fitness and Montreal Cognitive Assessment Scores in Older Adults.
|title=Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843126
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30459812
|full-text-url=https://sci-hub.do/10.1159/000489336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232269
}}
}}
* {{medline-title
* {{medline-title
|title=Metabolic adaptation of short-living growth hormone transgenic mice to methionine restriction and supplementation.
|title=One-Year Consumption of a Mediterranean-Like Dietary Pattern With Vitamin D3 Supplements Induced Small Scale but Extensive Changes of Immune Cell Phenotype, Co-receptor Expression and Innate Immune Responses in Healthy Elderly Subjects: Results From the United Kingdom Arm of the NU-AGE Trial.
|date=04.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29722030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30093866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070774
}}
}}
* {{medline-title
* {{medline-title
|title=Does the use of outdoor fitness equipment by older adults qualify as moderate to vigorous physical activity?
|title=Membrane-Bound [[CD40]]L Promotes Senescence and Initiates Senescence-Associated Secretory Phenotype via NF-κB Activation in Lung Adenocarcinoma.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29709035
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30078020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927431
|full-text-url=https://sci-hub.do/10.1159/000492352
}}
}}
* {{medline-title
* {{medline-title
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|title=Effects of Immunosenescence on the Lower Expression of Surface Molecules in Neutrophils and Lymphocytes.
|date=07.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29866027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
|full-text-url=https://sci-hub.do/10.2174/1874609811666180605092234
}}
}}
* {{medline-title
* {{medline-title
|title=The metabolic equivalents of one-mile walking by older adults; implications for health promotion.
|title=Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice.
|date=2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29085799
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843140
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757150
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of age on fitness among female firefighters.
|title=Elderly dendritic cells respond to LPS/IFN-γ and [[CD40]]L stimulation despite incomplete maturation.
|date=01.10.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29016908
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29652910
|full-text-url=https://sci-hub.do/10.1093/occmed/kqx123
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898732
}}
}}
==ABR==
* {{medline-title
* {{medline-title
|title=[Hidden hearing loss and early identification].
|title=C-Reactive Protein Impairs Dendritic Cell Development, Maturation, and Function: Implications for Peripheral Tolerance.
|date=07.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32791650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29556231
|full-text-url=https://sci-hub.do/10.13201/j.issn.2096-7993.2020.07.023
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845098
}}
}}
* {{medline-title
* {{medline-title
|title=Aging But Not Age-Related Hearing Loss Dominates the Decrease of Parvalbumin Immunoreactivity in the Primary Auditory Cortex of Mice.
|title=Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin-utrophin double knockout mice.
|date=05-06.2020
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32327469
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29255177
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865115
}}
}}
* {{medline-title
* {{medline-title
|title=Hearing loss through apoptosis of the spiral ganglion neurons in apolipoprotein E knockout mice fed with a western diet.
|title=Age-Associated B Cells Express a Diverse Repertoire of V  and Vκ Genes with Somatic Hypermutation.
|date=12.03.2020
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31948760
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28093524
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.12.100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322232
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of enriched endogenous omega-3 fatty acids on age-related hearing loss in mice.
|title=Autoimmune manifestations in aged mice arise from early-life immune dysregulation.
|date=26.11.2019
|date=19.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27798262
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291695
}}
}}
* {{medline-title
* {{medline-title
|title=Hearing impairment and associated morphological changes in pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice.
|title=The age-related neuroinflammatory environment promotes macrophage activation, which negatively impacts synaptic function.
|date=10.10.2019
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31601840
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27255823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787024
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.04.001
}}
}}
* {{medline-title
* {{medline-title
|title=Global nurse/midwife workforce and reproductive health through social ecology lens.
|title=Combinatorial approach to cancer immunotherapy: strength in numbers.
|date=09.2019
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31402489
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27256570
|full-text-url=https://sci-hub.do/10.1111/phn.12648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608090
}}
}}
* {{medline-title
* {{medline-title
|title=Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise-induced threshold shift.
|title=Human mesothelioma induces defects in dendritic cell numbers and antigen-processing function which predict survival outcomes.
|date=08.2019
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31270820
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27057464
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852351
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801471
}}
}}
* {{medline-title
* {{medline-title
|title=Age‑associated variation in the expression and function of TMEM16A calcium‑activated chloride channels in the cochlear stria vascularis of guinea pigs.
|title=Skewing of peritoneal resident macrophages toward M1-like is involved in enhancement of inflammatory responses induced by secondary necrotic neutrophils in aged mice.
|date=08.2019
|date=06-07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257512
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26965995
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625423
|full-text-url=https://sci-hub.do/10.1016/j.cellimm.2016.03.001
}}
}}
* {{medline-title
* {{medline-title
|title=Hormone replacement therapy attenuates hearing loss: Mechanisms involving estrogen and the IGF-1 pathway.
|title=Blood-borne biomarkers of mortality risk: systematic review of cohort studies.
|date=06.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30845368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26039142
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454670
}}
}}
* {{medline-title
* {{medline-title
|title=Evidence for age-related cochlear synaptopathy in humans unconnected to speech-in-noise intelligibility deficits.
|title=Age-associated modifications of intestinal permeability and innate immunity in human small intestine.
|date=15.03.2019
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710791
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25948052
|full-text-url=https://sci-hub.do/10.1016/j.heares.2019.01.017
|full-text-url=https://sci-hub.do/10.1042/CS20150046
}}
}}
* {{medline-title
* {{medline-title
|title=Masking Differentially Affects Envelope-following Responses in Young and Aged Animals.
|title=Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarction.
|date=21.08.2018
|date=15.02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29953908
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25485899
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329482
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Age on Speech-in-Noise Identification: Subjective Ratings of Hearing Difficulties and Encoding of Fundamental Frequency in Older Adults.
|title=Maturation of innate responses to mycobacteria over the first nine months of life.
|date=06.2018
|date=15.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719950
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24733845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048703
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Differences in Hearing Function and Cochlear Morphology between Male and Female Fischer 344 Rats.
|title=IL-2/[[CD40]]-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice.
|date=2017
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29354051
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24744051
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758597
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082580
}}
}}
==ELOVL2==
* {{medline-title
* {{medline-title
|title=The FBN rat model of aging: investigation of [[ABR]] waveforms and ribbon synapse changes.
|title=[[ELOVL2]]: Not just a biomarker of aging.
|date=02.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29107847
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33043173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544151
}}
}}
==CD36==
* {{medline-title
* {{medline-title
|title=Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease.
|title=The lipid elongation enzyme [[ELOVL2]] is a molecular regulator of aging in the retina.
|date=08.2020
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32638492
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31943697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996962
}}
}}
* {{medline-title
* {{medline-title
|title=Reduction of senescence-associated beta-galactosidase activity by vitamin E in human fibroblasts depends on subjects' age and cell passage number.
|title=Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts.
|date=07.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32479666
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156022
|full-text-url=https://sci-hub.do/10.1002/biof.1636
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691995
}}
}}
* {{medline-title
* {{medline-title
|title=Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system.
|title=Cell and tissue type independent age-associated DNA methylation changes are not rare but common.
|date=05.2020
|date=27.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32030468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30482885
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181452
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286821
}}
}}
* {{medline-title
* {{medline-title
|title=Human bone marrow adipocytes display distinct immune regulatory properties.
|title=DNA methylation of the [[ELOVL2]], [[FHL2]], [[KLF14]], C1orf132/MIR29B2C, and [[TRIM59]] genes for age prediction from blood, saliva, and buccal swab samples.
|date=08.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327694
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30300865
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711052
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken.
|title=Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing.
|date=01.09.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065718
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031222
|full-text-url=https://sci-hub.do/10.3382/ps/pez249
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.07.007
}}
}}
* {{medline-title
* {{medline-title
|title=Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis.
|title=Age-related DNA methylation changes are tissue-specific with [[ELOVL2]] promoter methylation as exception.
|date=22.01.2019
|date=30.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29848354
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.12.025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975493
}}
}}
* {{medline-title
* {{medline-title
|title=The adhesion and migration of microglia to β-amyloid (Aβ) is decreased with aging and inhibited by Nogo/NgR pathway.
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird.
|date=20.07.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30029608
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054753
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723
}}
}}
* {{medline-title
* {{medline-title
|title=Cell-surface phenotyping identifies [[CD36]] and CD97 as novel markers of fibroblast quiescence in lung fibrosis.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=01.11.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://sci-hub.do/10.1152/ajplung.00439.2017
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
* {{medline-title
* {{medline-title
|title=An evolutionary transcriptomics approach links [[CD36]] to membrane remodeling in replicative senescence.
|title=DNA methylation in [[ELOVL2]] and C1orf132 correctly predicted chronological age of individuals from three disease groups.
|date=06.08.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29974107
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28725932
|full-text-url=https://sci-hub.do/10.1039/c8mo00099a
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748441
}}
}}
* {{medline-title
* {{medline-title
|title=Comparative analysis of endothelial cell and sub-endothelial cell elastic moduli in young and aged mice: Role of [[CD36]].
|title=Independent validation of DNA-based approaches for age prediction in blood.
|date=25.07.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29954596
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28511095
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083865
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.04.020
}}
}}
* {{medline-title
* {{medline-title
|title=[[CD36]] initiates the secretory phenotype during the establishment of cellular senescence.
|title=Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines.
|date=06.2018
|date=12.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29777051
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28499412
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989758
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429538
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation.
|title=Systemic Age-Associated DNA Hypermethylation of [[ELOVL2]] Gene: In Vivo and In Vitro Evidences of a Cell Replication Process.
|date=05.2018
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27672102
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861890
}}
}}
* {{medline-title
* {{medline-title
|title=Developmental differences between neonatal and adult human erythropoiesis.
|title=Donor age and C1orf132/MIR29B2C determine age-related methylation signature of blood after allogeneic hematopoietic stem cell transplantation.
|date=08.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29274096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27602173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012039
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of high-fat diet and age on the blood lipidome and circulating endocannabinoids of female C57BL/6 mice.
|title=Forensic age prediction for dead or living samples by use of methylation-sensitive high resolution melting.
|date=01.2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986283
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27497326
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2017.09.011
|full-text-url=https://sci-hub.do/10.1016/j.legalmed.2016.05.001
}}
}}
==CDK4==
* {{medline-title
* {{medline-title
|title=Emerging Roles for the [i]INK4a/ARF[/i] ([i]CDKN2A[/i]) Locus in Adipose Tissue: Implications for Obesity and Type 2 Diabetes.
|title=Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system.
|date=22.09.2020
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32971832
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27337627
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563355
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2016.06.005
}}
}}
* {{medline-title
* {{medline-title
|title=Guilu Erxian Glue () Inhibits Chemotherapy-Induced Bone Marrow Hematopoietic Stem Cell Senescence in Mice May via p16 -Rb Signaling Pathway.
|title=Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model.
|date=11.2020
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32915425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26861500
|full-text-url=https://sci-hub.do/10.1007/s11655-020-3098-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798846
}}
}}
* {{medline-title
* {{medline-title
|title=Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
|title=Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study.
|date=22.05.2020
|date=09.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31112603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26861258
|full-text-url=https://sci-hub.do/10.1093/gerona/glz077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746895
}}
}}
* {{medline-title
* {{medline-title
|title=Ribosomal protein RPL22/eL22 regulates the cell cycle by acting as an inhibitor of the [[CDK4]]-cyclin D complex.
|title=Improved age determination of blood and teeth samples using a selected set of DNA methylation markers.
|date=03-04.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30874462
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26280308
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844214
}}
}}
* {{medline-title
* {{medline-title
|title=p16  deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence.
|title=Development of a forensically useful age prediction method based on DNA methylation analysis.
|date=09.2019
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30811968
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26026729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708504
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2015.05.001
}}
}}
* {{medline-title
* {{medline-title
|title=Efficient immortalization of cells derived from critically endangered Tsushima leopard cat (Prionailurus bengalensis euptilurus) with expression of mutant [[CDK4]], Cyclin D1, and telomerase reverse transcriptase.
|title=Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs.
|date=12.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225752
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24789080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269356
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082572
}}
}}
==REST==
* {{medline-title
* {{medline-title
|title=Effects of Fibronectin 1 on Cell Proliferation, Senescence and Apoptosis of Human Glioma Cells Through the PI3K/AKT Signaling Pathway.
|title=[Brain and Neuronal Aging: Aged Brain Controls via Gene Expression Fidelity and Master Regulatory Factors].
|date=2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115559
|full-text-url=https://sci-hub.do/10.1159/000492096
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00193-4
}}
}}
* {{medline-title
* {{medline-title
|title=Cyclin D1 depletion interferes with oxidative balance and promotes cancer cell senescence.
|title=Effect of 9 - PAHSA on cognitive dysfunction in diabetic mice and its possible mechanism.
|date=25.06.2018
|date=09.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29880532
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32014256
|full-text-url=https://sci-hub.do/10.1242/jcs.214726
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.01.071
}}
}}
* {{medline-title
* {{medline-title
|title=Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis.
|title=Increased [[REST]] to Optimize Life Span?
|date=06.04.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29642406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31762373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923408
|full-text-url=https://sci-hub.do/10.1089/rej.2019.2287
}}
}}
* {{medline-title
* {{medline-title
|title=Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line.
|title=Cardiac baroreflex hysteresis is one of the determinants of the heart period variability asymmetry.
|date=2018
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29405784
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31365303
|full-text-url=https://sci-hub.do/10.1080/21691401.2018.1434187
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00112.2019
}}
}}
* {{medline-title
* {{medline-title
|title=Mechanistic understanding of the role of [[ATRX]] in senescence provides new insight for combinatorial therapies with [[CDK4]] inhibitors.
|title=Pterostilbene Improves Cognitive Performance in Aged Rats: An in Vivo Study.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29404388
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30816671
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791849
|full-text-url=https://sci-hub.do/10.33594/000000017
}}
}}
* {{medline-title
* {{medline-title
|title=Glutaredoxin-1 Silencing Induces Cell Senescence via p53/p21/p16 Signaling Axis.
|title=Comparison between probabilistic and Wiener-Granger causality in assessing modifications of the cardiac baroreflex control with age.
|date=02.03.2018
|date=22.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29356545
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30207986
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.7b00761
|full-text-url=https://sci-hub.do/10.1088/1361-6579/aae0ec
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|title=Fast-Evolving Human-Specific Neural Enhancers Are Associated with Aging-Related Diseases.
|date=08.01.2018
|date=23.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29792826
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972385
}}
}}
* {{medline-title
* {{medline-title
|title=Preclinical characterization of abemaciclib in hormone receptor positive breast cancer.
|title=Influence of age and gender on the phase and strength of the relation between heart period and systolic blood pressure spontaneous fluctuations.
|date=19.09.2017
|date=01.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29050219
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29212671
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642494
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00903.2017
}}
}}
==DMD==
* {{medline-title
* {{medline-title
|title=Aldehyde dehydrogenases contribute to skeletal muscle homeostasis in healthy, aging, and Duchenne muscular dystrophy patients.
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=08.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32157826
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
}}
* {{medline-title
* {{medline-title
|title=Life expectancy at birth in Duchenne muscular dystrophy: a systematic review and meta-analysis.
|title=MicroRNA Expression Analysis of Centenarians and Rheumatoid Arthritis Patients Reveals a Common Expression Pattern.
|date=07.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32107739
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28824293
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387367
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562112
}}
}}
* {{medline-title
* {{medline-title
|title=Renal dysfunction can occur in advanced-stage Duchenne muscular dystrophy.
|title=The rs1277306 Variant of the [[REST]] Gene Confers Susceptibility to Cognitive Aging in an Elderly Taiwanese Population.
|date=02.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31725904
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28142142
|full-text-url=https://sci-hub.do/10.1002/mus.26757
|full-text-url=https://sci-hub.do/10.1159/000455833
}}
}}
* {{medline-title
* {{medline-title
|title=The long dystrophin gene product Dp427 modulates retinal function and vascular morphology in response to age and retinal ischemia.
|title=Assessing the evolution of redundancy/synergy of spontaneous variability regulation with age.
|date=10.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31199961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28079528
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.104489
|full-text-url=https://sci-hub.do/10.1088/1361-6579/aa5908
}}
}}
* {{medline-title
* {{medline-title
|title=Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting.
|title=Sixty years old is the breakpoint of human frontal cortex aging.
|date=06.2019
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884219
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27979658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596404
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.12.010
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent changes in metabolite profile and lipid saturation in dystrophic mice.
|title=Is senescence-associated β-galactosidase a marker of neuronal senescence?
|date=05.2019
|date=06.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30848538
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27768595
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777843
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348379
}}
}}
* {{medline-title
* {{medline-title
|title=Muscle function and age are associated with loss of bone mineral density in Duchenne muscular dystrophy.
|title=Running for [[REST]]: Physical activity attenuates neuroinflammation in the hippocampus of aged mice.
|date=04.2019
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30623456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27477921
|full-text-url=https://sci-hub.do/10.1002/mus.26416
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2016.07.159
}}
}}
* {{medline-title
* {{medline-title
|title=Use of bone age for evaluating bone density in patients with Duchenne muscular dystrophy: A preliminary report.
|title=Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models.
|date=04.2019
|date=30.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30636004
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27265785
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417931
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135662
}}
}}
* {{medline-title
* {{medline-title
|title=Age- and Expertise-Related Differences of Sensorimotor Network Dynamics during Force Control.
|title=A gain-of-function senescence bypass screen identifies the homeobox transcription factor [[DLX2]] as a regulator of [[ATM]]-p53 signaling.
|date=15.09.2018
|date=01.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048784
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26833729
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.07.025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743059
}}
}}
* {{medline-title
* {{medline-title
|title=Mineralocorticoid Receptor Antagonists in Muscular Dystrophy Mice During Aging and Exercise.
|title=An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging.
|date=2018
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30010143
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25692570
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732783
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334892
}}
}}
* {{medline-title
* {{medline-title
|title=Calcium current properties in dystrophin-deficient ventricular cardiomyocytes from aged mdx mice.
|title=MicroRNA-9 controls dendritic development by targeting [[REST]].
|date=01.2018
|date=18.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29333726
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25406064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235007
}}
}}
* {{medline-title
* {{medline-title
|title=Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin-utrophin double knockout mice.
|title=Rcor2 underexpression in senescent mice: a target for inflammaging?
|date=12.2017
|date=23.07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29255177
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25051986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128581
}}
}}
* {{medline-title
* {{medline-title
|title=The experience of parents of adult sons with Duchenne muscular dystrophy regarding their prolonged roles as primary caregivers: a serial qualitative study.
|title=[[REST]] and stress resistance in ageing and Alzheimer's disease.
|date=04.2019
|date=27.03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24670762
|full-text-url=https://sci-hub.do/10.1080/09638288.2017.1408148
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110979
}}
}}
==SIRT7==
* {{medline-title
* {{medline-title
|title=Spatial and age-related changes in the microstructure of dystrophic and healthy diaphragms.
|title=[[SIRT7]] antagonizes human stem cell aging as a heterochromatin stabilizer.
|date=2017
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28877195
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32504224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587283
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305295
}}
}}
==FGF23==
* {{medline-title
* {{medline-title
|title=Phosphate as a Pathogen of Arteriosclerosis and Aging.
|title=Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri.
|date=08.10.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33028781
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075496
|full-text-url=https://sci-hub.do/10.5551/jat.RV17045
|full-text-url=https://sci-hub.do/10.1016/j.gep.2019.05.001
}}
}}
* {{medline-title
* {{medline-title
|title=Plasma Soluble αKlotho, Serum Fibroblast Growth Factor 23, and Mobility Disability in Community-Dwelling Older Adults.
|title=Advances in Cellular Characterization of the Sirtuin Isoform, [[SIRT7]].
|date=01.05.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32405607
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30510540
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7209777
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253933
}}
}}
* {{medline-title
* {{medline-title
|title=Protective effect of Polygonatum sibiricum Polysaccharide on D-galactose-induced aging rats model.
|title=The epigenetic regulator [[SIRT7]] guards against mammalian cellular senescence induced by ribosomal DNA instability.
|date=10.02.2020
|date=13.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32042011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052228
}}
}}
* {{medline-title
* {{medline-title
|title=[[FGF23]] expression is stimulated in transgenic α-Klotho longevity mouse model.
|title=Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas.
|date=05.12.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31801907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564694
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962016
|full-text-url=https://sci-hub.do/10.1007/s11102-018-0881-7
}}
}}
* {{medline-title
* {{medline-title
|title=Fibroblast growth factor 23 and symmetric dimethylarginine concentrations in geriatric cats.
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|date=11.2019
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31568615
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872607
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
}}
}}
* {{medline-title
* {{medline-title
|title=Muscle-bone crosstalk and potential therapies for sarco-osteoporosis.
|title=The effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome.
|date=09.2019
|date=31.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31106446
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28768896
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331460
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559174
}}
}}
* {{medline-title
* {{medline-title
|title=Extraskeletal Calcifications in Hutchinson-Gilford Progeria Syndrome.
|title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts.
|date=08.2019
|date=01.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31077852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|title=The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging.
|date=06.02.2019
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27699588
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
|full-text-url=https://sci-hub.do/10.1007/s11010-016-2836-5
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Changes and Effects of Bisphosphonates on Bone Turnover and Disease Progression in Fibrous Dysplasia of Bone.
|title=Molecular, Cellular, and Physiological Characterization of Sirtuin 7 ([[SIRT7]]).
|date=04.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30645769
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27246221
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233270
}}
}}
* {{medline-title
* {{medline-title
|title=Kotho and aging.
|title=miR-152 induces human dental pulp stem cell senescence by inhibiting [[SIRT7]] expression.
|date=09.2016
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26991832
 
|full-text-url=https://sci-hub.do/10.1002/1873-3468.12138
}}
}}
* {{medline-title
* {{medline-title
|title=The Klotho proteins in health and disease.
|title=Sirtuins, Cell Senescence, and Vascular Aging.
|date=01.2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26948035
|full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848124
}}
}}
* {{medline-title
* {{medline-title
|title=Wnt signaling in bone, kidney, intestine, and adipose tissue and interorgan interaction in aging.
|title=The expression levels of the sirtuins in patients with BCC.
|date=04.2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30101565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26631040
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372353
|full-text-url=https://sci-hub.do/10.1007/s13277-015-4522-8
}}
}}
* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Age-Related Changes in Sirtuin 7 Expression in Calorie-Restricted and Refed Rats.
|date=11.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26595207
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://sci-hub.do/10.1159/000441603
}}
}}
* {{medline-title
* {{medline-title
|title=New Insights into the Mechanism of Action of Soluble Klotho.
|title=Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum.
|date=2017
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29250031
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26556180
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715364
|full-text-url=https://sci-hub.do/10.1111/jsm.13035
}}
}}
==MAPT==
* {{medline-title
* {{medline-title
|title=Association of relative brain age with tobacco smoking, alcohol consumption, and genetic variants.
|title=Novel protein-protein interactions of TPPII, p53, and [[SIRT7]].
|date=30.01.2020
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32001736
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26169984
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992742
|full-text-url=https://sci-hub.do/10.1007/s11010-015-2507-y
}}
}}
* {{medline-title
* {{medline-title
|title=A blood-based nutritional risk index explains cognitive enhancement and decline in the multidomain Alzheimer prevention trial.
|title=Differential expression of sirtuins in the aging rat brain.
|date=2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31921969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944714
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424846
}}
}}
* {{medline-title
* {{medline-title
|title=Longitudinal associations of physical activity levels with morphological and functional changes related with aging: The [[MAPT]] study.
|title=Stressed [[SIRT7]]: facing a crossroad of senescence and immortality.
|date=12.2019
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31669813
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25970806
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110758
|full-text-url=https://sci-hub.do/10.1111/1440-1681.12423
}}
}}
* {{medline-title
* {{medline-title
|title=Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease.
|title=Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response.
|date=31.10.2019
|date=01.02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31673052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25445786
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823454
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2014.11.001
}}
}}
* {{medline-title
* {{medline-title
|title=Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective.
|title=A [[SIRT7]]-dependent acetylation switch of GABPβ1 controls mitochondrial function.
|date=01.2020
|date=04.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31604111
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25200183
|full-text-url=https://sci-hub.do/10.1016/j.pneurobio.2019.101716
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2014.08.001
}}
}}
* {{medline-title
* {{medline-title
|title=Factors associated with changes of the frailty status after age 70: Findings in the [[MAPT]] study.
|title=Comparative interactomes of [[SIRT6]] and [[SIRT7]]: Implication of functional links to aging.
|date=06.2019
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31005551
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24782448
|full-text-url=https://sci-hub.do/10.1016/j.annepidem.2019.03.008
|full-text-url=https://sci-hub.do/10.1002/pmic.201400001
}}
}}
==TEC==
* {{medline-title
* {{medline-title
|title=Mitophagy and NAD  inhibit Alzheimer disease.
|title=Vestibular function and cortical and sub-cortical alterations in an aging population.
|date=06.2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922179
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32904672
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526831
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457317
}}
}}
* {{medline-title
* {{medline-title
|title=Cognitive changes of older adults with an equivocal amyloid load.
|title=Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration.
|date=04.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30689016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32733450
|full-text-url=https://sci-hub.do/10.1007/s00415-019-09203-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358591
}}
}}
* {{medline-title
* {{medline-title
|title=Tauopathy: A common mechanism for neurodegeneration and brain aging.
|title=Postnatal Involution and Counter-Involution of the Thymus.
|date=03.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30668956
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32477366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377302
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235445
}}
}}
* {{medline-title
* {{medline-title
|title=Cinnamaldehyde Improves Lifespan and Healthspan in [i]Drosophila melanogaster[/i] Models for Alzheimer's Disease.
|title=Gender Disparity Impacts on Thymus Aging and LHRH Receptor Antagonist-Induced Thymic Reconstitution Following Chemotherapeutic Damage.
|date=2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32194555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136480
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062683
}}
}}
* {{medline-title
* {{medline-title
|title=Sex and age interact to determine clinicopathologic differences in Alzheimer's disease.
|title=Clonogenic Culture of Mouse Thymic Epithelial Cells.
|date=12.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30219939
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280837
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-9728-2_15
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of a 3-Year Multi-Domain Intervention with or without Omega-3 Supplementation on Cognitive Functions in Older Subjects with Increased CAIDE Dementia Scores.
|title=TREM1/3 Deficiency Impairs Tissue Repair After Acute Kidney Injury and Mitochondrial Metabolic Flexibility in Tubular Epithelial Cells.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865075
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354698
|full-text-url=https://sci-hub.do/10.3233/JAD-180209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629955
}}
}}
* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=Interplay between Follistatin, Activin A, and [[BMP4]] Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging.
|date=16.08.2019
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.05.045
}}
}}
* {{medline-title
* {{medline-title
|title=Interaction between a [[MAPT]] variant causing frontotemporal dementia and mutant [[APP]] affects axonal transport.
|title=Transgenic Exosomes for Thymus Regeneration.
|date=08.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29729423
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31110503
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998378
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499203
}}
}}
==SOX2==
* {{medline-title
* {{medline-title
|title=Multiple nanosecond pulsed electric fields stimulation with conductive poly(l-lactic acid)/carbon nanotubes films maintains the multipotency of mesenchymal stem cells during prolonged in vitro culture.
|title=Cell-type-specific role of lamin-B1 in thymus development and its inflammation-driven reduction in thymus aging.
|date=08.2020
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592324
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30968547
|full-text-url=https://sci-hub.do/10.1002/term.3088
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612680
}}
}}
* {{medline-title
* {{medline-title
|title=Subpopulations of miniature pig mesenchymal stromal cells with different differentiation potentials differ in the expression of octamer-binding transcription factor 4 and sex determining region Y-box 2.
|title=Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces.
|date=03.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32054231
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436911
}}
}}
* {{medline-title
* {{medline-title
|title=Increased Type I and Decreased Type II Hair Cells after Deletion of Sox2 in the Developing Mouse Utricle.
|title=Epithelial innate immunity mediates tubular cell senescence after kidney injury.
|date=01.12.2019
|date=24.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678344
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30674725
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2019.09.027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413792
}}
}}
* {{medline-title
* {{medline-title
|title='Stemness' and 'senescence' related escape pathways are dose dependent in lung cancer cells surviving post irradiation.
|title=Thymic Epithelial Cell Support of Thymopoiesis Does Not Require [i]Klotho[/i].
|date=01.09.2019
|date=01.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201845
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373854
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116562
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275142
}}
}}
* {{medline-title
* {{medline-title
|title=Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis.
|title=MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors.
|date=30.04.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30910981
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29226156
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500153
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684555
}}
}}
* {{medline-title
* {{medline-title
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|title=A Fine-Tune Role of Mir-125a-5p on [i]Foxn1[/i] During Age-Associated Changes in the Thymus.
|date=06.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28580184
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440108
}}
}}
* {{medline-title
* {{medline-title
|title=Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart.
|title=Mechanisms and kinetics of proliferation and fibrosis development in a mouse model of thyrocyte hyperplasia.
|date=07.01.2019
|date=06-07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30663680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27173733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207148
|full-text-url=https://sci-hub.do/10.1016/j.cellimm.2016.04.006
}}
}}
* {{medline-title
* {{medline-title
|title=A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation.
|title=Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution.
|date=02.10.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279449
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26983083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168501
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794177
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|title=Foxn1 Protein Expression in the Developing, Aging, and Regenerating Thymus.
|date=12.2018
|date=15.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26538393
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1502010
}}
}}
* {{medline-title
* {{medline-title
|title=Centenarians Overexpress Pluripotency-Related Genes.
|title=Young, proliferative thymic epithelial cells engraft and function in aging thymuses.
|date=16.08.2019
|date=15.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25870244
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481326
}}
}}
* {{medline-title
* {{medline-title
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|title=Regeneration of the aged thymus by a single transcription factor.
|date=10.04.2018
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24715454
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978836
}}
}}
* {{medline-title
* {{medline-title
|title=[[SOX2]] expression diminishes with ageing in several tissues in mice and humans.
|title=Meis1 is required for the maintenance of postnatal thymic epithelial cells.
|date=01.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29574045
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24594519
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.03.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942356
}}
* {{medline-title
|title=Identification of novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24465914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897650
}}
}}
==C6==
* {{medline-title
* {{medline-title
|title=Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.
|title=Evolution of the Aroma of Treixadura Wines during Bottle Aging.
|date=15.10.2017
|date=08.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29138277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33049919
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600726
}}
}}
* {{medline-title
* {{medline-title
|title=[[ZSCAN10]] expression corrects the genomic instability of iPSCs from aged donors.
|title=D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway.
|date=09.2017
|date=29.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32991321
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843481
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585072
}}
}}
==TFEB==
* {{medline-title
* {{medline-title
|title=A Novel Lipofuscin-detecting Marker of Senescence Relates With Hypoxia, Dysregulated Autophagy and With Poor Prognosis in Non-small-cell-lung Cancer.
|title=Alcohol Extracts From [i]Ganoderma lucidum[/i] Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents.
|date=11-12.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33144423
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971923
|full-text-url=https://sci-hub.do/10.21873/invivo.12154
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444160
}}
}}
* {{medline-title
* {{medline-title
|title=ESC-sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia.
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.
|date=05.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32440476
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237844
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829
}}
}}
* {{medline-title
* {{medline-title
|title=Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging.
|title=Population-Stratified Analysis of Bone Mineral Density Distribution in Cervical and Lumbar Vertebrae of Chinese from Quantitative Computed Tomography.
|date=2020
|date=09-10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32047576
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27587947
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007385
}}
}}
* {{medline-title
* {{medline-title
|title=Polyamines reverse immune senescence via the translational control of autophagy.
|title=Demographic aspects in cervical vertebral bodies' size and shape ([[C3]]-[[C7]]): a skeletal study.
|date=01.2020
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31679458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27544049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984486
|full-text-url=https://sci-hub.do/10.1016/j.spinee.2016.08.022
}}
}}
* {{medline-title
* {{medline-title
|title=Polyamines Control eIF5A Hypusination, [[TFEB]] Translation, and Autophagy to Reverse B Cell Senescence.
|title=Neonatal Benzo[a]pyrene Exposure Induces Oxidative Stress and DNA Damage Causing Neurobehavioural Changes during the Early Adolescence Period in Rats.
|date=03.10.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31474573
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27271523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863385
|full-text-url=https://sci-hub.do/10.1159/000446276
}}
}}
* {{medline-title
* {{medline-title
|title=Insulin-like peptides and the mTOR-[[TFEB]] pathway protect [i]Caenorhabditis elegans[/i] hermaphrodites from mating-induced death.
|title=Variations in Occipitocervical and Cervicothoracic Alignment Parameters Based on Age: A Prospective Study of Asymptomatic Volunteers Using Full-Body Radiographs.
|date=08.07.2019
|date=01.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282862
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27116113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697448
|full-text-url=https://sci-hub.do/10.1097/BRS.0000000000001644
}}
}}
* {{medline-title
* {{medline-title
|title=Double knockout of Akt2 and AMPK predisposes cardiac aging without affecting lifespan: Role of autophagy and mitophagy.
|title=Age-related brain atrophy may be mitigated by internal jugular vein enlargement in male individuals without neurologic disease.
|date=01.07.2019
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109453
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26911619
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530587
|full-text-url=https://sci-hub.do/10.1177/0268355516633610
}}
}}
* {{medline-title
* {{medline-title
|title=[[TFEB]] protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux.
|title=The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis.
|date=02.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414849
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26834465
|full-text-url=https://sci-hub.do/10.1016/j.joca.2018.10.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716725
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity.
|title=Depletion of B cell CLL/Lymphoma 11B Gene Expression Represses Glioma Cell Growth.
|date=08.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29781176
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26096706
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092298
|full-text-url=https://sci-hub.do/10.1007/s12035-015-9231-1
}}
}}
* {{medline-title
* {{medline-title
|title=Nuclear Export Inhibition Enhances HLH-30/[[TFEB]] Activity, Autophagy, and Lifespan.
|title=Are the standard parameters of cervical spine alignment and range of motion related to age, sex, and cervical disc degeneration?
|date=15.05.2018
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768192
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26091436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991088
|full-text-url=https://sci-hub.do/10.3171/2015.1.SPINE14489
}}
}}
* {{medline-title
* {{medline-title
|title=Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids.
|title=Age-related morphologic changes of the vertebral artery in the transverse process. Analysis by multidetector computed tomography angiography.
|date=04.2018
|date=01.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606629
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25931427
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952403
|full-text-url=https://sci-hub.do/10.1016/j.spinee.2015.04.031
}}
}}
* {{medline-title
* {{medline-title
|title=Small-molecule [[TFEB]] pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan.
|title=Role of the serotonin transporter gene locus in the response to S[[SRI]] treatment of major depressive disorder in late life.
|date=22.12.2017
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29273768
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25827644
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741634
|full-text-url=https://sci-hub.do/10.1177/0269881115578159
}}
}}
* {{medline-title
* {{medline-title
|title=Peroxisomes contribute to oxidative stress in neurons during doxorubicin-based chemotherapy.
|title=The Impact of Genetics on Physical Resilience and Successful Aging.
|date=01.2018
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29180229
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25818147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996272
|full-text-url=https://sci-hub.do/10.1177/0898264315577586
}}
}}
* {{medline-title
* {{medline-title
|title=TOR-mediated regulation of metabolism in aging.
|title=Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise.
|date=12.2017
|date=15.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28971552
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25827594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676073
|full-text-url=https://sci-hub.do/10.1152/ajpendo.00481.2014
}}
}}
==AFM==
* {{medline-title
* {{medline-title
|title=Photocatalytic aging process of Nano-TiO  coated polypropylene microplastics: Combining atomic force microscopy and infrared spectroscopy ([[AFM]]-IR) for nanoscale chemical characterization.
|title=Non-sirtuin histone deacetylases in the control of cardiac aging.
|date=15.02.2021
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33080556
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25791169
|full-text-url=https://sci-hub.do/10.1016/j.jhazmat.2020.124159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459895
}}
}}
* {{medline-title
* {{medline-title
|title=Nanoscale infrared, thermal and mechanical properties of aged microplastics revealed by an atomic force microscopy coupled with infrared spectroscopy ([[AFM]]-IR) technique.
|title=Engineering temporal accumulation of a low recalcitrance polysaccharide leads to increased [[C6]] sugar content in plant cell walls.
|date=20.11.2020
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32702545
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25586315
|full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2020.140944
|full-text-url=https://sci-hub.do/10.1111/pbi.12326
}}
}}
* {{medline-title
* {{medline-title
|title=Detecting zeta potential of polydimethylsiloxane (PDMS) in electrolyte solutions with atomic force microscope.
|title=The effects of age on the morphometry of the cervical spinal cord and spinal column in adult rats: an MRI-based study.
|date=15.10.2020
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32521351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25044631
|full-text-url=https://sci-hub.do/10.1016/j.jcis.2020.05.061
|full-text-url=https://sci-hub.do/10.1002/ar.22995
}}
}}
* {{medline-title
* {{medline-title
|title=Recent Applications of Advanced Atomic Force Microscopy in Polymer Science: A Review.
|title=Spontaneous age-related cervical disc degeneration in the sand rat.
|date=17.05.2020
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32429499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24515407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016433
}}
}}
==C7==
* {{medline-title
* {{medline-title
|title=Active fractions of mannoproteins derived from yeast cell wall stimulate innate and acquired immunity of adult and elderly dogs.
|title=The Vertebral Artery Convergence to the Cervical Spine in Elders.
|date=03.2020
|date=30.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32288071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32337923
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126846
|full-text-url=https://sci-hub.do/10.3897/folmed.61.e39418
}}
}}
* {{medline-title
* {{medline-title
|title=The Effect of Waste Engine Oil and Waste Polyethylene on UV Aging Resistance of Asphalt.
|title=Age-related Changes in Cervical Sagittal Alignment: A Radiographic Analysis.
|date=06.03.2020
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32155867
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31261278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182932
|full-text-url=https://sci-hub.do/10.1097/BRS.0000000000003082
}}
}}
* {{medline-title
* {{medline-title
|title=Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans.
|title=Early Intravenous Infusion of Mesenchymal Stromal Cells Exerts a Tissue Source Age-Dependent Beneficial Effect on Neurovascular Integrity and Neurobehavioral Recovery After Traumatic Cervical Spinal Cord Injury.
|date=25.02.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32098962
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591557
}}
}}
* {{medline-title
* {{medline-title
|title=Nanomechanical insights: Amyloid beta oligomer-induced senescent brain endothelial cells.
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.
|date=01.12.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31513781
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829
}}
}}
* {{medline-title
* {{medline-title
|title=Application of atomic force microscopy in the analysis of time since deposition (TSD) of red blood cells in bloodstains: A forensic analysis.
|title=Twenty-year Longitudinal Follow-up MRI Study of Asymptomatic Volunteers: The Impact of Cervical Alignment on Disk Degeneration.
|date=08.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31181409
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102637
|full-text-url=https://sci-hub.do/10.1016/j.forsciint.2019.05.048
|full-text-url=https://sci-hub.do/10.1097/BSD.0000000000000706
}}
}}
* {{medline-title
* {{medline-title
|title=Iceland spar calcite: Humidity and time effects on surface properties and their reversibility.
|title=The change of cervical spine alignment along with aging in asymptomatic population: a preliminary analysis.
|date=01.04.2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30682592
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28685403
|full-text-url=https://sci-hub.do/10.1016/j.jcis.2019.01.047
|full-text-url=https://sci-hub.do/10.1007/s00586-017-5209-1
}}
}}
* {{medline-title
* {{medline-title
|title=Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column.
|title=Lumbar Retrolisthesis in Aging Spine: What are the Associated Factors?
|date=08.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29747057
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28632553
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2018.05.004
|full-text-url=https://sci-hub.do/10.1097/BSD.0000000000000198
}}
}}
* {{medline-title
* {{medline-title
|title=Multiscale Poroviscoelastic Compressive Properties of Mouse Supraspinatus Tendons Are Altered in Young and Aged Mice.
|title=Three types of sagittal alignment regarding compensation in asymptomatic adults: the contribution of the spine and lower limbs.
|date=01.05.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29238818
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28589303
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816244
|full-text-url=https://sci-hub.do/10.1007/s00586-017-5159-7
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease.
|title=Age-related variations in global spinal alignment and sagittal balance in asymptomatic Japanese adults.
|date=11.2017
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28812215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28248611
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665708
|full-text-url=https://sci-hub.do/10.1080/01616412.2017.1296654
}}
}}
==ASL==
* {{medline-title
* {{medline-title
|title=Increased blood-brain barrier permeability to water in the aging brain detected using noninvasive multi-TE [[ASL]] MRI.
|title=Standing sagittal alignment of the whole axial skeleton with reference to the gravity line in humans.
|date=01.2021
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32910547
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28127750
|full-text-url=https://sci-hub.do/10.1002/mrm.28496
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382592
}}
* {{medline-title
|title=Population-Stratified Analysis of Bone Mineral Density Distribution in Cervical and Lumbar Vertebrae of Chinese from Quantitative Computed Tomography.
|date=09-10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27587947
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007385
}}
}}
* {{medline-title
* {{medline-title
|title=Quantitative Cerebrovascular Reactivity in Normal Aging: Comparison Between Phase-Contrast and Arterial Spin Labeling MRI.
|title=Demographic aspects in cervical vertebral bodies' size and shape ([[C3]]-[[C7]]): a skeletal study.
|date=2020
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849217
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27544049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411174
|full-text-url=https://sci-hub.do/10.1016/j.spinee.2016.08.022
}}
}}
* {{medline-title
* {{medline-title
|title=Correcting Task fMRI Signals for Variability in Baseline CBF Improves BOLD-Behavior Relationships: A Feasibility Study in an Aging Model.
|title=Prediction of Cervical Endplate Size: One Size Does Not Fit All.
|date=2020
|date=01.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32425745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27135446
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205008
|full-text-url=https://sci-hub.do/10.3928/01477447-20160427-11
}}
}}
* {{medline-title
* {{medline-title
|title=Cerebral Blood Flow in Community-Based Older Twins Is Moderately Heritable: An Arterial Spin Labeling Perfusion Imaging Study.
|title=Variations in Occipitocervical and Cervicothoracic Alignment Parameters Based on Age: A Prospective Study of Asymptomatic Volunteers Using Full-Body Radiographs.
|date=2019
|date=01.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31333444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27116113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615405
|full-text-url=https://sci-hub.do/10.1097/BRS.0000000000001644
}}
}}
* {{medline-title
* {{medline-title
|title=A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure.
|title=Age-related brain atrophy may be mitigated by internal jugular vein enlargement in male individuals without neurologic disease.
|date=15.08.2019
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31062904
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26911619
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693488
|full-text-url=https://sci-hub.do/10.1177/0268355516633610
}}
}}
* {{medline-title
* {{medline-title
|title=Cortical cerebral blood flow in ageing: effects of haematocrit, sex, ethnicity and diabetes.
|title=The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis.
|date=10.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30887200
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26834465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719435
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716725
}}
}}
* {{medline-title
* {{medline-title
|title=Exercise-stimulated arterial transit time in calf muscles measured by dynamic contrast-enhanced magnetic resonance imaging.
|title=Signal intensity loss of the intervertebral discs in the cervical spine of young patients on fluid sensitive sequences.
|date=01.2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30648355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26634254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333626
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717169
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of Coffee, Wine, and Chocolate Consumption on Cognitive Outcome and MRI Parameters in Old Age.
|title=The Cervical Spinal Canal Tapers Differently in Patients with Chiari I with and without Syringomyelia.
|date=01.10.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30275380
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26585256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212945
|full-text-url=https://sci-hub.do/10.3174/ajnr.A4597
}}
}}
* {{medline-title
* {{medline-title
|title=Potential Role of OERP as Early Marker of Mild Cognitive Impairment.
|title=Corticospinal tract development and spinal cord innervation differ between cervical and lumbar targets.
|date=2018
|date=21.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30271339
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25609632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605536
}}
}}
* {{medline-title
* {{medline-title
|title=Reduced Regional Cerebral Blood Flow Relates to Poorer Cognition in Older Adults With Type 2 Diabetes.
|title=Spontaneous age-related cervical disc degeneration in the sand rat.
|date=2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30250430
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24515407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139361
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016433
}}
}}
==CDKN2A==
* {{medline-title
* {{medline-title
|title=The Age-Related Perfusion Pattern Measured With Arterial Spin Labeling MRI in Healthy Subjects.
|title=Association between Nrf2 and [[CDKN2A]] expression in patients with end-stage renal disease: a pilot study.
|date=2018
|date=13.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30065646
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32661200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485736
}}
}}
* {{medline-title
* {{medline-title
|title=Resilience and amygdala function in older healthy and depressed adults.
|title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.
|date=09.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29754022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995579
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141
}}
}}
* {{medline-title
* {{medline-title
|title=Does Aerobic Exercise Influence Intrinsic Brain Activity? An Aerobic Exercise Intervention among Healthy Old Adults.
|title=Analysis of the putative tumor suppressor gene cdkn2ab in pigment cells and melanoma of Xiphophorus and medaka.
|date=2017
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28848424
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377863
}}
* {{medline-title
|title=In vitro behavior and UV response of melanocytes derived from carriers of [[[[CDKN2A]]]] mutations and [[MC1R]] variants.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117292
|full-text-url=https://sci-hub.do/10.1111/pcmr.12732
}}
* {{medline-title
|title=Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29735632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002945
}}
* {{medline-title
|title=Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16  inactivation.
|date=26.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482580
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828408
}}
* {{medline-title
|title=Cellular aging dynamics after acute malaria infection: A 12-month longitudinal study.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143441
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771395
}}
* {{medline-title
|title=[[ARID1A]] suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[[[CDKN2A]]]] regulatory axis.
|date=18.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942143
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.099
}}
* {{medline-title
|title=Cellular Senescence in Mouse Hippocampus After Irradiation and the Role of p53 and p21.
|date=01.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28340115
|full-text-url=https://sci-hub.do/10.1093/jnen/nlx006
}}
* {{medline-title
|title=Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28233611
|full-text-url=https://sci-hub.do/10.1016/j.kint.2016.12.018
}}
* {{medline-title
|title=ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A.
|date=24.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28184004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377799
}}
* {{medline-title
|title=Establishment and application of a novel patient-derived KIAA1549:[[BRAF]]-driven pediatric pilocytic astrocytoma model for preclinical drug testing.
|date=14.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28002790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355278
}}
* {{medline-title
|title=Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus.
|date=18.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26809688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871660
}}
* {{medline-title
|title=Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts.
|date=11-12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26794818
|full-text-url=https://sci-hub.do/10.7417/T.2015.1902
}}
* {{medline-title
|title=Alterations of telomere length and DNA methylation in hairdressers: A cross-sectional study.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26637967
|full-text-url=https://sci-hub.do/10.1002/em.21991
}}
* {{medline-title
|title=Genetics of melanoma progression: the rise and fall of cell senescence.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26386262
|full-text-url=https://sci-hub.do/10.1111/pcmr.12422
}}
* {{medline-title
|title=Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis.
|date=02.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824610
}}
* {{medline-title
|title=Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25963977
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450138
}}
* {{medline-title
|title=Y-27632, a ROCK inhibitor, delays senescence of putative murine salivary gland stem cells in culture.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25804560
|full-text-url=https://sci-hub.do/10.1016/j.archoralbio.2015.03.003
}}
* {{medline-title
|title=Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.
|date=29.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24876127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071561
}}
}}
==CXCL1==
==CXCL1==
Строка 6935: Строка 6997:
|full-text-url=https://sci-hub.do/10.17219/acem/61431
|full-text-url=https://sci-hub.do/10.17219/acem/61431
}}
}}
==EGFR==
* {{medline-title
* {{medline-title
|title=Type I Collagen Aging Increases Expression and Activation of [[EGFR]] and Induces Resistance to Erlotinib in Lung Carcinoma in 3D Matrix Model.
|title=Methyl caffeate and some plant constituents inhibit age-related inflammation: effects on senescence-associated secretory phenotype (SASP) formation.
|date=2020
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33014812
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28299617
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511549
|full-text-url=https://sci-hub.do/10.1007/s12272-017-0909-y
}}
* {{medline-title
|title=Adiponectin induces [[CXCL1]] secretion from cancer cells and promotes tumor angiogenesis by inducing stromal fibroblast senescence.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27092462
|full-text-url=https://sci-hub.do/10.1002/mc.22428
}}
}}
* {{medline-title
* {{medline-title
|title=Comparative effectiveness and cost-effectiveness of three first-line [[EGFR]]-tyrosine kinase inhibitors: Analysis of real-world data in a tertiary hospital in Taiwan.
|title=Senescent peritoneal mesothelium induces a pro-angiogenic phenotype in ovarian cancer cells in vitro and in a mouse xenograft model in vivo.
|date=2020
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32267879
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26433963
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141611
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740564
}}
}}
* {{medline-title
* {{medline-title
|title=An Optogenetic Method to Study Signal Transduction in Intestinal Stem Cell Homeostasis.
|title=[[CXCL1]] Triggers Caspase-3 Dependent Tau Cleavage in Long-Term Neuronal Cultures and in the Hippocampus of Aged Mice: Implications in Alzheimer's Disease.
|date=01.05.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32201167
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26401931
|full-text-url=https://sci-hub.do/10.1016/j.jmb.2020.03.019
|full-text-url=https://sci-hub.do/10.3233/JAD-150041
}}
}}
* {{medline-title
* {{medline-title
|title=Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway.
|title=Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts.
|date=13.01.2020
|date=15.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31935369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26093063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146079
|full-text-url=https://sci-hub.do/10.1016/j.bcp.2015.06.013
}}
}}
* {{medline-title
* {{medline-title
|title=Association between [[EGFR]] mutation and ageing, history of pneumonia and gastroesophageal reflux disease among patients with advanced lung cancer.
|title=Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
|date=11.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634646
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26011191
|full-text-url=https://sci-hub.do/10.1016/j.ejca.2019.09.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444306
}}
}}
* {{medline-title
* {{medline-title
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms.
|title=Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice.
|date=22.07.2019
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318
|full-text-url=https://sci-hub.do/10.1016/j.patbio.2015.03.002
}}
}}
==CXCR4==
* {{medline-title
* {{medline-title
|title=The role of [[EGFR]] signaling in age-related osteoporosis in mouse cortical bone.
|title=Aging-Related Reduced Expression of [[CXCR4]] on Bone Marrow Mesenchymal Stromal Cells Contributes to Hematopoietic Stem and Progenitor Cell Defects.
|date=10.2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32418119
|full-text-url=https://sci-hub.do/10.1096/fj.201900436RR
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395885
}}
}}
* {{medline-title
* {{medline-title
|title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes.
|title=Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/[[CXCR4]] signalling pathway.
|date=13.06.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32384208
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600
|full-text-url=https://sci-hub.do/10.1002/ejhf.1840
}}
}}
* {{medline-title
* {{medline-title
|title=[[EGF]]/[[EGF]]R upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence.
|title=Stromal Cell-Derived Factor 1 Protects Brain Vascular Endothelial Cells from Radiation-Induced Brain Damage.
|date=04.12.2018
|date=10.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514230
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31658727
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830118
}}
}}
* {{medline-title
* {{medline-title
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|title=A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.
|date=06.2019
|date=19.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30709741
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2019.01.002
}}
}}
* {{medline-title
* {{medline-title
|title=Quantum Modeling: A Bridge between the Pumping and Signaling Functions of Na/K-ATPase.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=09.08.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30096926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121303
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
* {{medline-title
* {{medline-title
|title=Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer.
|title=Reducing [[CXCR4]] Resulted in Impairing Proliferation and Promoting Aging.
|date=30.03.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29682186
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30080220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908287
|full-text-url=https://sci-hub.do/10.1007/s12603-018-1013-9
}}
}}
* {{medline-title
* {{medline-title
|title=Withanolide A extends the lifespan in human [[EGFR]]-driven cancerous Caenorhabditis elegans.
|title=Targeting junctional adhesion molecule-C ameliorates sepsis-induced acute lung injury by decreasing [[CXCR4]] aged neutrophils.
|date=04.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29427754
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088666
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258282
}}
}}
==HMGB1==
* {{medline-title
* {{medline-title
|title=Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction.
|title=Tumor microenvironment in functional adrenocortical adenomas: immune cell infiltration in cortisol-producing adrenocortical adenoma.
|date=02.12.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596893
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885734
|full-text-url=https://sci-hub.do/10.1016/j.humpath.2018.03.016
}}
}}
* {{medline-title
* {{medline-title
|title=Targeting [[HMGB1]] by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells.
|title=Lower resting and exercise-induced circulating angiogenic progenitors and angiogenic T cells in older men.
|date=14.07.2019
|date=01.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31303606
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167123
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660056
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00592.2017
}}
}}
* {{medline-title
* {{medline-title
|title=[[HMGB1]] and Caveolin-1 related to [[RPE]] cell senescence in age-related macular degeneration.
|title=Adipose-Derived Mesenchymal Stem Cells from the Elderly Exhibit Decreased Migration and Differentiation Abilities with Senescent Properties.
|date=07.07.2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31284269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29113467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660032
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680952
}}
}}
* {{medline-title
* {{medline-title
|title=Dual faced [[HMGB1]] plays multiple roles in cardiomyocyte senescence and cardiac inflammatory injury.
|title=Conversion of adult endothelium to immunocompetent haematopoietic stem cells.
|date=06.2019
|date=25.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31129019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28514438
|full-text-url=https://sci-hub.do/10.1016/j.cytogfr.2019.05.009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794215
}}
}}
* {{medline-title
* {{medline-title
|title=Neuroprotective Effect of Dioscin on the Aging Brain.
|title=Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells.
|date=30.03.2019
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30935017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28329136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479446
|full-text-url=https://sci-hub.do/10.1093/gerona/glw336
}}
}}
* {{medline-title
* {{medline-title
|title=Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging.
|title=The expression of the [[BPI]]FB4 and [[CXCR4]] associates with sustained health in long-living individuals from Cilento-Italy.
|date=23.03.2019
|date=22.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30903794
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461165
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361669
}}
}}
* {{medline-title
* {{medline-title
|title=Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis.
|title=Age and Human Regenerative Capacity Impact of Cardiovascular Risk Factors.
|date=30.04.2019
|date=16.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30910981
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27436845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500153
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026592
}}
}}
* {{medline-title
* {{medline-title
|title=Serum and nutrient deprivation increase autophagic flux in intervertebral disc annulus fibrosus cells: an in vitro experimental study.
|title=Effect of age on expression of spermatogonial markers in bovine testis and isolated cells.
|date=05.2019
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30847707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27180120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538458
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2016.04.004
}}
}}
* {{medline-title
* {{medline-title
|title=Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
|title=Increased susceptibility of [[CD4]]  T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced [[CD4]] and enhanced [[CXCR4]] and [[FAS]] surface expression levels.
|date=01.05.2019
|date=09.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735837
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26452480
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.02.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600300
}}
}}
* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=A single fas gene mutation changes lupus onset, severity, location, and molecular abnormalities in mice.
|date=11.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25941813
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://sci-hub.do/10.2174/1566524015666150505162638
}}
}}
* {{medline-title
* {{medline-title
|title=Repeated abortion in adulthood induces cognition impairment in aged mice.
|title=Caloric restriction and the adipokine leptin alter the SDF-1 signaling axis in bone marrow and in bone marrow derived mesenchymal stem cells.
|date=30.07.2018
|date=15.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061639
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25779533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065382
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706462
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of DNA polymerase β induces cellular senescence.
|title=[[CXCR4]] blockade induces atherosclerosis by affecting neutrophil function.
|date=08.2018
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29968395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24816217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203593
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418455
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of [[BDNF]]/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
|title=Trafficking phenotype and production of granzyme B by double negative B cells (IgG( )IgD(-)CD27(-)) in the elderly.
|date=06.03.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29065194
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24389059
|full-text-url=https://sci-hub.do/10.1093/ntr/ntx157
|full-text-url=https://sci-hub.do/10.1016/j.exger.2013.12.011
}}
}}
==MDM2==
==ERG==


* {{medline-title
* {{medline-title
|title=SENEBLOC, a long non-coding RNA suppresses senescence via p53-dependent and independent mechanisms.
|title=Effect of age and sex on neurodevelopment and neurodegeneration in the healthy eye: Longitudinal functional and structural study in the Long-Evans rat.
|date=06.04.2020
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32030426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32882213
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102969
|full-text-url=https://sci-hub.do/10.1016/j.exer.2020.108208
}}
}}
* {{medline-title
* {{medline-title
|title=Disruption of Robo2-Baiap2 integrated signaling drives cystic disease.
|title=Mice With a Combined Deficiency of Superoxide Dismutase 1 (Sod1), DJ-1 (Park7), and Parkin (Prkn) Develop Spontaneous Retinal Degeneration With Aging.
|date=19.09.2019
|date=03.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31534052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31487745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733419
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence-induced immunophenotype, gene expression and electrophysiology changes in human amniocytes.
|title=Test-retest repeatability of the pattern electroretinogram and flicker electroretinogram.
|date=11.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31478614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31312944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815807
|full-text-url=https://sci-hub.do/10.1007/s10633-019-09707-5
}}
}}
* {{medline-title
* {{medline-title
|title=Hsp90β interacts with [[MDM2]] to suppress p53-dependent senescence during skeletal muscle regeneration.
|title=Regeneration of Dopaminergic Neurons in Adult Zebrafish Depends on Immune System Activation and Differs for Distinct Populations.
|date=10.2019
|date=12.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31313490
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30948475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561686
}}
}}
* {{medline-title
* {{medline-title
|title=TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway.
|title=Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
|date=07.03.2019
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30845965
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735837
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404308
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.02.005
}}
}}
* {{medline-title
* {{medline-title
|title=Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells.
|title=Further Characterization of the Predominant Inner Retinal Degeneration of Aging Cln3  Knock-In Mice.
|date=28.02.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30647108
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29721970
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367206
|full-text-url=https://sci-hub.do/10.1007/978-3-319-75402-4_50
}}
}}
* {{medline-title
* {{medline-title
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|title=Two novel forms of [[ERG]] oscillation in Drosophila: age and activity dependence.
|date=19.10.2018
|date=03-06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29688104
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233714
}}
}}
* {{medline-title
* {{medline-title
|title=The Dysfunctional [[MDM2]]-p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy.
|title=Loss of [[XBP1]] accelerates age-related decline in retinal function and neurodegeneration.
|date=11.2018
|date=04.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131393
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615095
|full-text-url=https://sci-hub.do/10.2337/db18-0684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883257
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of [[CCNB1]] silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer.
|title=The Complement System Is Critical in Maintaining Retinal Integrity during Aging.
|date=01.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30069972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29497373
|full-text-url=https://sci-hub.do/10.1002/jcp.26816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818470
}}
}}
* {{medline-title
* {{medline-title
|title=Boosting [[ATM]] activity alleviates aging and extends lifespan in a mouse model of progeria.
|title=EDI OCT evaluation of choroidal thickness in Stargardt disease.
|date=02.05.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717979
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755895
}}
}}
* {{medline-title
* {{medline-title
|title=Acute [[HSF1]] depletion induces cellular senescence through the [[MDM2]]-p53-p21 pathway in human diploid fibroblasts.
|title=Intensity response function of the photopic negative response (PhNR): effect of age and test-retest reliability.
|date=08.05.2018
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632240
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28508299
|full-text-url=https://sci-hub.do/10.1242/jcs.210724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197057
}}
}}
* {{medline-title
* {{medline-title
|title=Relevance of the p53-[[MDM2]] axis to aging.
|title=Nonamyloidogenic processing of amyloid beta precursor protein is associated with retinal function improvement in aging male [[APP]] /PS1ΔE9 mice.
|date=01.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29192902
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28262325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729541
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.02.004
}}
}}
* {{medline-title
* {{medline-title
|title=Pomegranate peel extract attenuates D-galactose-induced oxidative stress and hearing loss by regulating PNUTS/PP1 activity in the mouse cochlea.
|title=Absence of DJ-1 causes age-related retinal abnormalities in association with increased oxidative stress.
|date=11.2017
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28837860
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28088625
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.07.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328840
}}
}}
==PTH==
* {{medline-title
* {{medline-title
|title=Vitamin D Receptor Polymorphisms in Sex-Frailty Paradox.
|title=Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease.
|date=05.09.2020
|date=23.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32899460
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27338814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551757
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918017
}}
}}
* {{medline-title
* {{medline-title
|title=Parathyroid hormone ameliorates temporomandibular joint osteoarthritic-like changes related to age.
|title=Age-related change in fast adaptation mechanisms measured with the scotopic full-field [[ERG]].
|date=04.2020
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32154622
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27126339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162802
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356483
}}
}}
* {{medline-title
* {{medline-title
|title=A Vitamin D, Calcium and Leucine-Enriched Whey Protein Nutritional Supplement Improves Measures of Bone Health in Sarcopenic Non-Malnourished Older Adults: The PROVIDE Study.
|title=Relation of [[BAALC]] and [[ERG]] Gene Expression with Overall Survival in Acute Myeloid Leukemia Cases.
|date=10.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31338563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26625814
|full-text-url=https://sci-hub.do/10.1007/s00223-019-00581-6
|full-text-url=https://sci-hub.do/10.7314/apjcp.2015.16.17.7875
}}
}}
* {{medline-title
* {{medline-title
|title=EVALUATION OF PLASMA 25-HYDROXYVITAMIN D, IONIZED CALCIUM, AND PARATHYROID HORMONE IN GREEN SEA TURTLES ([i]CHELONIA MYDAS[/i]) EXPOSED TO DIFFERENT INTENSITIES OF ULTRAVIOLET B RADIATION.
|title=Differences in Retinal Structure and Function between Aging Male and Female Sprague-Dawley Rats are Strongly Influenced by the Estrus Cycle.
|date=13.06.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26317201
|full-text-url=https://sci-hub.do/10.1638/2017-0115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552560
}}
}}
* {{medline-title
* {{medline-title
|title=The relative influence of serum ionized calcium and 25-hydroxyvitamin D in regulating [[PTH]] secretion in healthy subjects.
|title=Lack of Acid Sphingomyelinase Induces Age-Related Retinal Degeneration.
|date=08.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31129357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168297
|full-text-url=https://sci-hub.do/10.1016/j.bone.2019.05.029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500403
}}
}}
* {{medline-title
* {{medline-title
|title=Vitamin D in Relation to Incident Sarcopenia and Changes in Muscle Parameters Among Older Adults: The KORA-Age Study.
|title=Changes in rod and cone-driven oscillatory potentials in the aging human retina.
|date=08.2019
|date=17.07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31069442
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25034601
|full-text-url=https://sci-hub.do/10.1007/s00223-019-00558-5
|full-text-url=https://sci-hub.do/10.1167/iovs.14-14219
}}
}}
* {{medline-title
* {{medline-title
|title=Extraskeletal Calcifications in Hutchinson-Gilford Progeria Syndrome.
|title=The effect of ageing on ocular blood flow, oxygen tension and retinal function during and after intraocular pressure elevation.
|date=08.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31077852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24866182
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035318
}}
}}
==FES==
* {{medline-title
* {{medline-title
|title=Sequential Treatment with Eldecalcitol After [[PTH]] Improves Bone Mechanical Properties of Lumbar Spine and Femur in Aged Ovariectomized Rats.
|title=An outpatient Tai Chi program: Effects on veterans' functional outcomes.
|date=03.2019
|date=26.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30467731
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33241873
|full-text-url=https://sci-hub.do/10.1007/s00223-018-0497-y
|full-text-url=https://sci-hub.do/10.1111/nuf.12532
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Vitamin D Treatment on Glucose Homeostasis and Metabolism in Lebanese Older Adults: A Randomized Controlled Trial.
|title=Gait Function in Adults Aged 50 Years and Older With Spina Bifida.
|date=2018
|date=07.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30379314
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33166524
|full-text-url=https://sci-hub.do/10.1007/s12603-018-1083-8
|full-text-url=https://sci-hub.do/10.1016/j.apmr.2020.10.118
}}
}}
* {{medline-title
* {{medline-title
|title=Testosterone level in aging male with different glucose tolerance state and its association with osteocalcin.
|title=A Single Question as a Screening Tool to Assess Fear of Falling in Young-Old Community-Dwelling Persons.
|date=03.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30039993
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32165062
|full-text-url=https://sci-hub.do/10.1080/13685538.2018.1481940
|full-text-url=https://sci-hub.do/10.1016/j.jamda.2020.01.101
}}
}}
* {{medline-title
* {{medline-title
|title=Early effects of parathyroid hormone on vascularized bone regeneration and implant osseointegration in aged rats.
|title=Fall-related efficacy is a useful and independent index to detect fall risk in Japanese community-dwelling older people: a 1-year longitudinal study.
|date=10.2018
|date=29.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29960821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31664911
|full-text-url=https://sci-hub.do/10.1016/j.biomaterials.2018.06.035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820944
}}
}}
* {{medline-title
* {{medline-title
|title=Mito-mice∆ and mitochondrial DNA mutator mice as models of human osteoporosis caused not by aging but by hyperparathyroidism.
|title=Investigating Changes in Real-time Conscious Postural Processing by Older Adults during Different Stance Positions Using Electroencephalography Coherence.
|date=01.11.2018
|date=10-12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29973435
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31514583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219885
|full-text-url=https://sci-hub.do/10.1080/0361073X.2019.1664450
}}
}}
* {{medline-title
* {{medline-title
|title=Intermittent [[PTH]] 1-34 administration improves the marrow microenvironment and endothelium-dependent vasodilation in bone arteries of aged rats.
|title=Effectiveness of Daily Use of Bilateral Custom-Made Ankle-Foot Orthoses on Balance, Fear of Falling, and Physical Activity in Older Adults: A Randomized Controlled Trial.
|date=01.06.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29420158
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30504728
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530116
}}
}}
==TEC==
* {{medline-title
* {{medline-title
|title=Vestibular function and cortical and sub-cortical alterations in an aging population.
|title=Decline in sensorimotor systems explains reduced falls self-efficacy.
|date=08.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32904672
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30015133
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457317
|full-text-url=https://sci-hub.do/10.1016/j.jelekin.2018.07.001
}}
* {{medline-title
|title=Fear of Falling in Older Adults with Diabetes Mellitus: The IMIAS Study.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29956644
|full-text-url=https://sci-hub.do/10.1017/S071498081800020X
}}
}}
* {{medline-title
* {{medline-title
|title=Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration.
|title=Cross-cultural adaptation and measurement properties testing of the Iconographical Falls Efficacy Scale (Icon-[[FES]]).
|date=2020
|date=07-08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32733450
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486980
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358591
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095044
}}
}}
* {{medline-title
* {{medline-title
|title=Postnatal Involution and Counter-Involution of the Thymus.
|title=Binocular Vision Disorders and Visual Attention: Associations With Balance and Mobility in Older Adults.
|date=2020
|date=01.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32477366
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28714802
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235445
|full-text-url=https://sci-hub.do/10.1123/japa.2016-0349
}}
}}
* {{medline-title
* {{medline-title
|title=Gender Disparity Impacts on Thymus Aging and LHRH Receptor Antagonist-Induced Thymic Reconstitution Following Chemotherapeutic Damage.
|title=Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS.
|date=2020
|date=25.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32194555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28545453
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062683
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445414
}}
}}
* {{medline-title
* {{medline-title
|title=Clonogenic Culture of Mouse Thymic Epithelial Cells.
|title=[[FES]] in Europe and Beyond: Current Translational Research.
|date=2019
|date=15.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396938
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28078074
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-9728-2_15
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220221
}}
}}
* {{medline-title
* {{medline-title
|title=TREM1/3 Deficiency Impairs Tissue Repair After Acute Kidney Injury and Mitochondrial Metabolic Flexibility in Tubular Epithelial Cells.
|title=Use it or Lose It: Tonic Activity of Slow Motoneurons Promotes Their Survival and Preferentially Increases Slow Fiber-Type Groupings in Muscles of Old Lifelong Recreational Sportsmen.
|date=2019
|date=15.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354698
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28078066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220213
}}
}}
* {{medline-title
* {{medline-title
|title=Interplay between Follistatin, Activin A, and [[BMP4]] Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging.
|title=Recovery from muscle weakness by exercise and [[FES]]: lessons from Masters, active or sedentary seniors and SCI patients.
|date=25.06.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27592133
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.05.045
|full-text-url=https://sci-hub.do/10.1007/s40520-016-0619-1
}}
}}
* {{medline-title
* {{medline-title
|title=Transgenic Exosomes for Thymus Regeneration.
|title=Biology of Muscle Atrophy and of its Recovery by [[FES]] in Aging and Mobility Impairments: Roots and By-Products.
|date=2019
|date=24.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31110503
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26913160
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499203
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748978
}}
}}
* {{medline-title
* {{medline-title
|title=Cell-type-specific role of lamin-B1 in thymus development and its inflammation-driven reduction in thymus aging.
|title=Balance Disorders in the Elderly: Does Instability Increase Over Time?
|date=08.2019
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30968547
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26848036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612680
|full-text-url=https://sci-hub.do/10.1177/0003489416629979
}}
}}
* {{medline-title
* {{medline-title
|title=Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces.
|title=Age group classification and gender detection based on forced expiratory spirometry.
|date=03.2019
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26736321
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436911
|full-text-url=https://sci-hub.do/10.1109/EMBC.2015.7318421
}}
}}
* {{medline-title
* {{medline-title
|title=Epithelial innate immunity mediates tubular cell senescence after kidney injury.
|title=Is there a relationship between short [[FES]]-I test scores and objective assessment of balance in the older people with age-induced instability?
|date=24.01.2019
|date=01-02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30674725
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26412554
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413792
|full-text-url=https://sci-hub.do/10.1016/j.archger.2015.09.005
}}
}}
* {{medline-title
* {{medline-title
|title=Thymic Epithelial Cell Support of Thymopoiesis Does Not Require [i]Klotho[/i].
|title=Age-associated declines in muscle mass, strength, power, and physical performance: impact on fear of falling and quality of life.
|date=01.12.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373854
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26194491
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275142
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960453
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors.
|title=Effects of functional electric stimulation cycle ergometry training on lower limb musculature in acute sci individuals.
|date=2017
|date=01.09.2005
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29226156
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24453530
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887329
}}
}}
==ATF4==
==JAK2==


* {{medline-title
* {{medline-title
|title=Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78-Loaded Extracellular Vesicles.
|title=Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity.
|date=10.12.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33297752
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850477
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.120.315506
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399640
}}
}}
* {{medline-title
* {{medline-title
|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells.
|title=Quercetin Directly Targets [[JAK2]] and PKCδ and Prevents UV-Induced Photoaging in Human Skin.
|date=01.2020
|date=23.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31652815
|full-text-url=https://sci-hub.do/10.1111/pcmr.12811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862686
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic and age-dependent effects of the spongiform neurodegeneration-associated [[MGRN1]] E3 ubiquitin ligase on mitochondrial homeostasis.
|title=[Red blood cell lifespan detected by endogenous carbon monoxide breath test in patients with polycythemia vera].
|date=06.2019
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089807
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31594177
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639055
|full-text-url=https://sci-hub.do/10.3760/cma.j.issn.0578-1426.2019.10.010
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=Roles of [[JAK2]] in Aging, Inflammation, Hematopoiesis and Malignant Transformation.
|date=08.2019
|date=08.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31398915
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721738
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of a resistance-training programme on endoplasmic reticulum unfolded protein response and mitochondrial functions in PBMCs from elderly subjects.
|title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver.
|date=08.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30614406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918
|full-text-url=https://sci-hub.do/10.1080/17461391.2018.1561950
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667
}}
}}
* {{medline-title
* {{medline-title
|title=[Protective effect of Wuzi Yanzong recipe on testicular germ cell apoptosis in natural ageing rats through endoplasmic reticulum stress].
|title=Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development.
|date=10.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453716
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30417440
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180530.001
|full-text-url=https://sci-hub.do/10.1002/jcp.27752
}}
}}
* {{medline-title
* {{medline-title
|title=Protective effect of Wuzi Yanzong recipe on testicular dysfunction through inhibition of germ cell apoptosis in ageing rats via endoplasmic reticulum stress.
|title=Distinctive features of polycythaemia vera in New Zealand Polynesians.
|date=03.2019
|date=21.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30393883
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235191
|full-text-url=https://sci-hub.do/10.1111/and.13181
 
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of NRF-2 and [[PGC]]-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|date=01.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30253279
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156745
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender.
|date=2018
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0
}}
}}
* {{medline-title
* {{medline-title
|title=De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver.
|title=Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.
|date=05.2018
|date=23.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28538171
|full-text-url=https://sci-hub.do/10.1530/JME-18-0018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457484
}}
}}
* {{medline-title
* {{medline-title
|title=Resveratrol modulates response against acute inflammatory stimuli in aged mouse brain.
|title=The Dyslexia-susceptibility Protein [[KIAA0319]] Inhibits Axon Growth Through Smad2 Signaling.
|date=02.2018
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29174969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28334068
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905272
}}
}}
* {{medline-title
* {{medline-title
|title=Integrated stress response stimulates [[FGF21]] expression: Systemic enhancer of longevity.
|title=JAK-STAT signaling mediates the senescence of bone marrow-mesenchymal stem cells from systemic lupus erythematosus patients.
|date=12.2017
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28844867
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28177455
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2017.08.009
|full-text-url=https://sci-hub.do/10.1093/abbs/gmw134
}}
}}
==CCR2==
* {{medline-title
* {{medline-title
|title=Hip Fracture Leads to Transitory Immune Imprint in Older Patients.
|title=Oxidative stress induces the decline of brain [[EPO]] expression in aging rats.
|date=2020
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33072114
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27452792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533556
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.07.012
}}
}}
* {{medline-title
* {{medline-title
|title=The CC-chemokine receptor 2 is involved in the control of ovarian folliculogenesis and fertility lifespan in mice.
|title=Scribble is required for pregnancy-induced alveologenesis in the adult mammary gland.
|date=09.2020
|date=15.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32615332
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27179074
|full-text-url=https://sci-hub.do/10.1016/j.jri.2020.103174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920253
}}
}}
* {{medline-title
* {{medline-title
|title=Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity.
|title=Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression.
|date=08.2020
|date=03.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32543720
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27121132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041879
}}
}}
* {{medline-title
* {{medline-title
|title=Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction.
|title=Exogenous H2S contributes to recovery of ischemic post-conditioning-induced cardioprotection by decrease of ROS level via down-regulation of NF-κB and [[JAK2]]-[[STAT3]] pathways in the aging cardiomyocytes.
|date=26.03.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32154790
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27096074
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836181
}}
}}
* {{medline-title
* {{medline-title
|title=Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by [[CCR2]].
|title=Correlation Analysis Between Expression Levels of Hepatic Growth Hormone Receptor, Janus Kinase 2, Insulin-Like Growth Factor-I Genes and Dwarfism Phenotype in Bama Minipig.
|date=02.2020
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26353733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013280
|full-text-url=https://sci-hub.do/10.1166/jnn.2015.9001
}}
}}
* {{medline-title
* {{medline-title
|title=Klotho-mediated targeting of CCL2 suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments.
|title=Emerging drugs for the treatment of myelofibrosis.
|date=11.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545552
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26153237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822285
|full-text-url=https://sci-hub.do/10.1517/14728214.2015.1061502
}}
}}
* {{medline-title
* {{medline-title
|title=Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90 + subset.
|title=[[PLA2R1]]: expression and function in cancer.
|date=10.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31353772
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24667060
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718537
|full-text-url=https://sci-hub.do/10.1016/j.bbcan.2014.03.003
}}
}}
* {{medline-title
* {{medline-title
|title=Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells.
|title=Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing.
|date=14.11.2018
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429354
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24531222
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445267
|full-text-url=https://sci-hub.do/10.1007/s00125-014-3185-0
}}
}}
==MMP9==
* {{medline-title
* {{medline-title
|title=Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain.
|title=[[EGR1]] promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling.
|date=30.05.2018
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29848996
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201921
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032263
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.06.010
}}
}}
* {{medline-title
* {{medline-title
|title=Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging.
|title=[Effect of saponins extracted from Panax japonicas on inhibiting myocardial fibrosis by TGF-β1/Smad3 signaling pathway in aging rats].
|date=05.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30593247
|full-text-url=https://sci-hub.do/10.1002/cyto.a.23372
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180724.006
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of Radiation-Induced Ccl2 Signaling Protects Lungs from Vascular Dysfunction and Endothelial Cell Loss.
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|date=10.01.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|full-text-url=https://sci-hub.do/10.1089/ars.2017.7458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
}}
}}
* {{medline-title
* {{medline-title
|title=Attenuated Macrophage Infiltration in Glomeruli of Aged Mice Resulting in Ameliorated Kidney Injury in Nephrotoxic Serum Nephritis.
|title=Oxidative stress induces p38MAPK-dependent senescence in the feto-maternal interface cells.
|date=10.08.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415117
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941169
|full-text-url=https://sci-hub.do/10.1093/gerona/gly019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023622
}}
}}
==CFI==
* {{medline-title
* {{medline-title
|title=Psychosocial Resources for Hedonic Balance, Life Satisfaction and Happiness in the Elderly: A Path Analysis.
|title=Activation of DNA demethylases attenuates aging-associated arterial stiffening and hypertension.
|date=06.08.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32781590
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459462
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052484
}}
}}
* {{medline-title
* {{medline-title
|title=Validity and Reliability of the Flourishing Scale in a Sample of Older Adults in Iran.
|title=Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice.
|date=2020
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32546985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244746
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823768
}}
}}
* {{medline-title
* {{medline-title
|title=The decision about retirement: A scale to describe representations and practices of medical doctors and nurses.
|title=Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1.
|date=07-08.2016
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32258559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866058
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806742
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2016.10.002
}}
}}
* {{medline-title
* {{medline-title
|title=Family versus intimate partners: Estimating who matters more for health in a 20-year longitudinal study.
|title=Secondhand Smoke Exposure Enhances Cardiac Fibrosis Effects on the Aging Rat Hearts.
|date=03.2020
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31697103
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27713609
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012715
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052479
}}
}}
* {{medline-title
* {{medline-title
|title=Adapting and validating the Rosenberg Self-Esteem Scale for elderly Spanish population.
|title=Transcriptome Analysis of B Cell Immune Functions in Periodontitis: Mucosal Tissue Responses to the Oral Microbiome in Aging.
|date=02.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524131
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27486459
|full-text-url=https://sci-hub.do/10.1017/S1041610219001170
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947588
}}
}}
* {{medline-title
* {{medline-title
|title=Mediating Role of Fall-related Efficacy in a Fall Prevention Program.
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|date=01.03.2019
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|full-text-url=https://sci-hub.do/10.5993/AJHB.43.2.15
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
}}
}}
* {{medline-title
* {{medline-title
|title=An application of Bayesian measurement invariance to modelling cognition over time in the English Longitudinal Study of Ageing.
|title=Differential Matrix Metalloprotease (MMP) Expression Profiles Found in Aged Gingiva.
|date=12.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30350427
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492125
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938517
}}
}}
* {{medline-title
* {{medline-title
|title=[New semantic-cultural validation and psychometric study of the CASP-19 scale in adult and elderly Brazilians].
|title=Inflammageing assessed by [[MMP9]] in normal Japanese individuals and the patients with Werner syndrome.
|date=11.10.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30329002
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27195193
|full-text-url=https://sci-hub.do/10.1590/0102-311X00181417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869575
}}
* {{medline-title
|title=Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26859687
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844783
}}
}}
* {{medline-title
* {{medline-title
|title=Mental status evaluation in older adults with cancer: Development of the Mental Health Index-13.
|title=The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4.
|date=03.2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30205939
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26445208
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408306
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237386
}}
}}
* {{medline-title
* {{medline-title
|title=The ACTIVE conceptual framework as a structural equation model.
|title=Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis.
|date=01-02.2018
|date=02.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29303475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793899
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824610
}}
}}
* {{medline-title
* {{medline-title
|title=The Utility of the Cognitive Function Instrument ([[CFI]]) to Detect Cognitive Decline in Non-Demented Older Adults.
|title=Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition.
|date=2017
|date=06.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854503
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26400086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646369
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of age on the response of retinal capillary filling to changes in intraocular pressure measured by optical coherence tomography angiography.
|title=Fat and Sucrose Intake Induces Obesity-Related Bone Metabolism Disturbances: Kinetic and Reversibility Studies in Growing and Adult Rats.
|date=01.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782513
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26175082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681409
|full-text-url=https://sci-hub.do/10.1002/jbmr.2596
}}
}}
==DNMT3A==
* {{medline-title
* {{medline-title
|title=Epigenetic regulation of miR-29a/miR-30c/[[DNMT3A]] axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells.
|title=Endothelin-1 critically influences cardiac function via superoxide-[[MMP9]] cascade.
|date=09.09.2020
|date=21.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32961441
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25848038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413291
}}
}}
* {{medline-title
* {{medline-title
|title=Collagens and DNA methyltransferases in mare endometrosis.
|title=[The expression of differential and matrix remodelling factors in human buccal epithelium in aging].
|date=09.2019
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31512314
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640689
|full-text-url=https://sci-hub.do/10.1111/rda.13515
 
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related clonal haemopoiesis is associated with increased epigenetic age.
|title=A transcriptional roadmap to the senescence and differentiation of human oral keratinocytes.
|date=19.08.2019
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31430471
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24398559
|full-text-url=https://sci-hub.do/10.1016/j.cub.2019.07.011
|full-text-url=https://sci-hub.do/10.1093/gerona/glt212
}}
}}
==TFEB==
* {{medline-title
* {{medline-title
|title=Alcohol Extracts From [i]Ganoderma lucidum[/i] Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents.
|title=A Novel Lipofuscin-detecting Marker of Senescence Relates With Hypoxia, Dysregulated Autophagy and With Poor Prognosis in Non-small-cell-lung Cancer.
|date=2019
|date=11-12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971923
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33144423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444160
|full-text-url=https://sci-hub.do/10.21873/invivo.12154
}}
}}
* {{medline-title
* {{medline-title
|title=Targeted, Amplicon-Based, Next-Generation Sequencing to Detect Age-Related Clonal Hematopoiesis.
|title=ESC-sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia.
|date=2019
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30941718
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32440476
|full-text-url=https://sci-hub.do/10.1007/7651_2019_216
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237844
}}
}}
* {{medline-title
* {{medline-title
|title=Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development.
|title=Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging.
|date=06.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30417440
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32047576
|full-text-url=https://sci-hub.do/10.1002/jcp.27752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007752
}}
}}
* {{medline-title
* {{medline-title
|title=Concise Review: Age-Related Clonal Hematopoiesis: Stem Cells Tempting the Devil.
|title=Polyamines reverse immune senescence via the translational control of autophagy.
|date=09.2018
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31679458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984486
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Parental Aging During Embryo Development and Adult Life: The Case of Nothobranchius furzeri.
|title=Polyamines Control eIF5A Hypusination, [[TFEB]] Translation, and Autophagy to Reverse B Cell Senescence.
|date=04.2018
|date=03.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304310
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31474573
|full-text-url=https://sci-hub.do/10.1089/zeb.2017.1494
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863385
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|title=Insulin-like peptides and the mTOR-[[TFEB]] pathway protect [i]Caenorhabditis elegans[/i] hermaphrodites from mating-induced death.
|date=2017
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697448
}}
}}
* {{medline-title
* {{medline-title
|title=An inflammatory environment containing TNFα favors Tet2-mutant clonal hematopoiesis.
|title=Double knockout of Akt2 and AMPK predisposes cardiac aging without affecting lifespan: Role of autophagy and mitophagy.
|date=03.2018
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109453
|full-text-url=https://sci-hub.do/10.1016/j.exphem.2017.11.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530587
}}
}}
* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=[[TFEB]] protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux.
|date=2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414849
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://sci-hub.do/10.1016/j.joca.2018.10.011
}}
}}
* {{medline-title
* {{medline-title
|title=How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?
|title=Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity.
|date=2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28792951
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29781176
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092298
}}
}}
==EZH2==
* {{medline-title
* {{medline-title
|title=Linking gene expression and phenotypic changes in the developmental and evolutionary origins of osteosclerosis in the ribs of bowhead whales (Balaena mysticetus).
|title=Nuclear Export Inhibition Enhances HLH-30/[[TFEB]] Activity, Autophagy, and Lifespan.
|date=09.2020
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32729176
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768192
|full-text-url=https://sci-hub.do/10.1002/jez.b.22990
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991088
}}
}}
* {{medline-title
* {{medline-title
|title=[[EZH2]] is involved in vulnerability to neuroinflammation and depression-like behaviors induced by chronic stress in different aged mice.
|title=Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids.
|date=01.07.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32553389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606629
|full-text-url=https://sci-hub.do/10.1016/j.jad.2020.03.154
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952403
}}
}}
* {{medline-title
* {{medline-title
|title=A positive feedback loop between [[EZH2]] and NOX4 regulates nucleus pulposus cell senescence in age-related intervertebral disc degeneration.
|title=Small-molecule [[TFEB]] pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan.
|date=2020
|date=22.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32025238
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29273768
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741634
}}
}}
* {{medline-title
* {{medline-title
|title=Perinatal exposure to bisphenol A impacts in the mammary gland morphology of adult Mongolian gerbils.
|title=Peroxisomes contribute to oxidative stress in neurons during doxorubicin-based chemotherapy.
|date=04.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917966
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29180229
|full-text-url=https://sci-hub.do/10.1016/j.yexmp.2020.104374
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996272
}}
}}
* {{medline-title
* {{medline-title
|title=Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing [[ABI3BP]] in gallbladder cancer cells.
|title=TOR-mediated regulation of metabolism in aging.
|date=07.06.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28971552
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676073
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic Co-Deregulation of [[EZH2]]/[[TET1]] is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer.
|title=Nuclear AMPK regulated [[CARM1]] stabilization impacts autophagy in aged heart.
|date=2019
|date=29.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30809307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28315332
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376470
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.03.053
}}
}}
* {{medline-title
* {{medline-title
|title=Improving Treatment for Myelodysplastic Syndromes Patients.
|title=[[TFEB]] ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin.
|date=25.10.2018
|date=16.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362079
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27992857
|full-text-url=https://sci-hub.do/10.1007/s11864-018-0583-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270683
}}
}}
* {{medline-title
* {{medline-title
|title=Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration.
|title=Role of [[TFEB]] Mediated Autophagy, Oxidative Stress, Inflammation, and Cell Death in Endotoxin Induced Myocardial Toxicity of Young and Aged Mice.
|date=25.09.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30257200
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27200146
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261459
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856916
}}
}}
* {{medline-title
* {{medline-title
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
|title=Critical role of lysosomes in the dysfunction of human Cardiac Stem Cells obtained from failing hearts.
|date=05.11.2018
|date=01.08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27153139
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005
|full-text-url=https://sci-hub.do/10.1016/j.ijcard.2016.04.155
}}
}}
* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=Mondo complexes regulate [[TFEB]] via TOR inhibition to promote longevity in response to gonadal signals.
|date=05.2017
|date=22.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27001890
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804169
}}
}}
* {{medline-title
* {{medline-title
|title=Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways.
|title=Transcriptional and epigenetic regulation of autophagy in aging.
|date=27.03.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590617
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25836756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915310
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502732
}}
}}
* {{medline-title
==ACE2==
|title=Region specific knock-out reveals distinct roles of chromatin modifiers in adult neurogenic niches.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433384
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914887
}}
==HGF==


* {{medline-title
* {{medline-title
|title=Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4  T cell subsets.
|title=How Does SARS-CoV-2 Affect the Central Nervous System? A Working Hypothesis.
|date=19.11.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33223447
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304284
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155367
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701095
}}
}}
* {{medline-title
* {{medline-title
|title=Hepatocyte growth factor ([[HGF]]) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling pathways.
|title=Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2.
|date=31.07.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736659
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33112891
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393921
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592753
}}
}}
* {{medline-title
* {{medline-title
|title=Phenytoin sodium-ameliorated gingival fibroblast aging is associated with autophagy.
|title=A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures.
|date=10.2020
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32281104
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32854108
|full-text-url=https://sci-hub.do/10.1111/jre.12750
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2708-8
}}
}}
* {{medline-title
* {{medline-title
|title=Impaired integrin α  /β  -mediated hepatocyte growth factor release by stellate cells of the aged liver.
|title=COVID-19 and Senotherapeutics: Any Role for the Naturally-occurring Dipeptide Carnosine?
|date=04.2020
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32157808
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32765939
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189994
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7390525
}}
}}
* {{medline-title
* {{medline-title
|title=Evaluation of the biological behaviour of various dental implant abutment materials on attachment and viability of human gingival fibroblasts.
|title=The dual impact of [[ACE2]] in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions.
|date=07.2019
|date=15.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31060818
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32653522
|full-text-url=https://sci-hub.do/10.1016/j.dental.2019.04.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347488
}}
}}
* {{medline-title
* {{medline-title
|title=Characterization of aged rat vocal fold fibroblasts.
|title=The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of "inflame-aging".
|date=03.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30450675
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32529477
|full-text-url=https://sci-hub.do/10.1002/lary.27464
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289226
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults.
|title=Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis.
|date=09.2018
|date=01.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354979
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32510973
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101979
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381712
}}
}}
* {{medline-title
* {{medline-title
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging.
|title=A Mouse Model of SARS-CoV-2 Infection and Pathogenesis.
|date=26.10.2018
|date=08.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32485164
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250783
}}
}}
* {{medline-title
* {{medline-title
|title=Hepatocyte growth factor is a potential biomarker for osteoproliferation and osteoporosis in ankylosing spondylitis.
|title=COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches.
|date=02.2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30306221
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32430627
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449322
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237344
}}
}}
* {{medline-title
* {{medline-title
|title=Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor.
|title=Gut microbiota and Covid-19- possible link and implications.
|date=09.03.2018
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29523193
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32430279
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845161
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217790
}}
}}
* {{medline-title
* {{medline-title
|title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway.
|title=Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes.
|date=2018
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32389499
|full-text-url=https://sci-hub.do/10.1159/000487559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252014
}}
}}
* {{medline-title
* {{medline-title
|title=Cell-size-dependent upregulation of [[HGF]] expression in dermal fibroblasts: Impact on human skin connective tissue aging.
|title=Restoration of the Renin-Angiotensin System Balance Is a Part of the Effect of Fasting on Cardiovascular Rejuvenation: Role of Age and Fasting Models.
|date=12.2017
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28826691
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31571520
|full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2017.08.003
|full-text-url=https://sci-hub.do/10.1089/rej.2019.2254
}}
}}
==KL==
* {{medline-title
* {{medline-title
|title=The goddess who spins the thread of life: Klotho, psychiatric stress, and accelerated aging.
|title=Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in [[ACE2]]-knockout mice.
|date=08.2019
|date=30.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31519791
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660403
|full-text-url=https://sci-hub.do/10.1042/CS20190573
}}
}}
* {{medline-title
* {{medline-title
|title=[i][[KL]]OTHO[/i] heterozygosity attenuates [i]APOE4[/i]-related amyloid burden in preclinical AD.
|title=Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study.
|date=16.04.2019
|date=14.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30867273
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089908
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517452
}}
}}
* {{medline-title
* {{medline-title
|title=Utilizing Atlas-Based Modeling to Predict Knee Joint Cartilage Degeneration: Data from the Osteoarthritis Initiative.
|title=The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system.
|date=03.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30547410
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407880
|full-text-url=https://sci-hub.do/10.1007/s10439-018-02184-y
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2018.01.043
}}
}}
* {{medline-title
* {{medline-title
|title=Impaired proteostasis in senescent vascular endothelial cells: a perspective on estrogen and oxidative stress in the aging vasculature.
|title=Sex differences in the aging pattern of renin-angiotensin system serum peptidases.
|date=01.02.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30499713
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28174624
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00318.2018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291971
}}
}}
* {{medline-title
* {{medline-title
|title=Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis.
|title=Chymase-dependent production of angiotensin II: an old enzyme in old hearts.
|date=04.2019
|date=01.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30488497
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27815252
|full-text-url=https://sci-hub.do/10.1002/em.22247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336578
}}
}}
* {{medline-title
* {{medline-title
|title=Klotho at the Edge of Alzheimer's Disease and Senile Depression.
|title=Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice.
|date=03.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978424
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27200147
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1200-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855022
}}
}}
* {{medline-title
* {{medline-title
|title=Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity.
|title=Angiotensin converting enzyme 2/Ang-(1-7)/mas axis protects brain from ischemic injury with a tendency of age-dependence.
|date=10.2018
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24581232
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840841
}}
==CFI==
 
* {{medline-title
|title=Psychosocial Resources for Hedonic Balance, Life Satisfaction and Happiness in the Elderly: A Path Analysis.
|date=06.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32781590
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7459462
}}
}}
* {{medline-title
* {{medline-title
|title=G-395A polymorphism in the promoter region of the [[KL]]OTHO gene associates with frailty among the oldest-old.
|title=Validity and Reliability of the Flourishing Scale in a Sample of Older Adults in Iran.
|date=30.04.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712948
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32546985
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244746
}}
}}
* {{medline-title
* {{medline-title
|title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling.
|title=The decision about retirement: A scale to describe representations and practices of medical doctors and nurses.
|date=2017
|date=07-08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32258559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806742
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|title=Family versus intimate partners: Estimating who matters more for health in a 20-year longitudinal study.
|date=01.2018
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31697103
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012715
}}
}}
* {{medline-title
* {{medline-title
|title=Anti-aging factor, serum alpha-Klotho, as a marker of acute physiological stress, and a predictor of ICU mortality, in patients with septic shock.
|title=Adapting and validating the Rosenberg Self-Esteem Scale for elderly Spanish population.
|date=04.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29268200
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524131
|full-text-url=https://sci-hub.do/10.1016/j.jcrc.2017.11.023
|full-text-url=https://sci-hub.do/10.1017/S1041610219001170
}}
}}
* {{medline-title
* {{medline-title
|title=Secreted αKlotho isoform protects against age-dependent memory deficits.
|title=Mediating Role of Fall-related Efficacy in a Fall Prevention Program.
|date=09.2018
|date=01.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29086766
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808478
|full-text-url=https://sci-hub.do/10.1038/mp.2017.211
|full-text-url=https://sci-hub.do/10.5993/AJHB.43.2.15
}}
}}
==PAH==
* {{medline-title
* {{medline-title
|title=Changes in light absorption by brown carbon in soot particles due to heterogeneous ozone aging in a smog chamber.
|title=An application of Bayesian measurement invariance to modelling cognition over time in the English Longitudinal Study of Ageing.
|date=11.2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32771846
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30350427
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2020.115273
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492125
}}
}}
* {{medline-title
* {{medline-title
|title=Factors associated with pulmonary arterial hypertension ([[PAH]]) in systemic sclerosis (SSc).
|title=[New semantic-cultural validation and psychometric study of the CASP-19 scale in adult and elderly Brazilians].
|date=09.2020
|date=11.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659476
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30329002
|full-text-url=https://sci-hub.do/10.1016/j.autrev.2020.102602
|full-text-url=https://sci-hub.do/10.1590/0102-311X00181417
}}
}}
* {{medline-title
* {{medline-title
|title=Potentially Avoidable Hospitalization among Long-Term Care Insurance Beneficiaries with Dementia.
|title=Mental status evaluation in older adults with cancer: Development of the Mental Health Index-13.
|date=09.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32316707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30205939
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509129
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408306
}}
}}
* {{medline-title
* {{medline-title
|title=Burden of disease at the same limit of exposure to airborne polycyclic aromatic hydrocarbons varies significantly across countries depending on the gap in longevity.
|title=The ACTIVE conceptual framework as a structural equation model.
|date=30.09.2019
|date=01-02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31108419
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29303475
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2019.04.028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793899
}}
}}
* {{medline-title
* {{medline-title
|title=Converging Paths of Pulmonary Arterial Hypertension and Cellular Senescence.
|title=The Utility of the Cognitive Function Instrument ([[CFI]]) to Detect Cognitive Decline in Non-Demented Older Adults.
|date=07.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30758225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854503
|full-text-url=https://sci-hub.do/10.1165/rcmb.2018-0329TR
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417419
}}
}}
* {{medline-title
* {{medline-title
|title=Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in [[CYP1A1]]-overexpressing breast cancer cells.
|title=The effect of age on the response of retinal capillary filling to changes in intraocular pressure measured by optical coherence tomography angiography.
|date=15.12.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782513
|full-text-url=https://sci-hub.do/10.1016/j.bmc.2018.11.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681409
}}
}}
* {{medline-title
* {{medline-title
|title=Exposure to Polycyclic Aromatic Hydrocarbons and Accelerated DNA Methylation Aging.
|title=Health, coping and subjective well-being: results of a longitudinal study of elderly Israelis.
|date=06.2018
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29906262
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26829654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108582
|full-text-url=https://sci-hub.do/10.1080/13607863.2016.1141285
}}
}}
* {{medline-title
* {{medline-title
|title=Arrhythmias in adult patients with congenital heart disease and pulmonary arterial hypertension.
|title=Women's intentions to use fertility preservation to prevent age-related fertility decline.
|date=12.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29776964
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26611498
|full-text-url=https://sci-hub.do/10.1136/heartjnl-2017-312881
|full-text-url=https://sci-hub.do/10.1016/j.rbmo.2015.10.007
}}
* {{medline-title
|title=Factorial Structure and Measurement Invariance of the PANAS in Spanish Older Adults.
|date=03.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26054863
|full-text-url=https://sci-hub.do/10.1017/sjp.2015.6
}}
}}
* {{medline-title
* {{medline-title
|title=Reduced bioavailability and plant uptake of polycyclic aromatic hydrocarbons from soil slurry amended with biochars pyrolyzed under various temperatures.
|title=Assessing the factor structure of well-being in older adults: findings from the National Health and Aging Trends Study.
|date=06.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29627960
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25915703
|full-text-url=https://sci-hub.do/10.1007/s11356-018-1874-9
|full-text-url=https://sci-hub.do/10.1080/13607863.2015.1037245
}}
}}
* {{medline-title
* {{medline-title
|title=Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice.
|title=Measuring frailty using self-report and test-based health measures.
|date=14.03.2018
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540228
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25687601
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411224
}}
}}
* {{medline-title
* {{medline-title
|title=Changes of total and freely dissolved polycyclic aromatic hydrocarbons and toxicity of biochars treated with various aging processes.
|title=CASP-19 special section: how does chronic disease status affect CASP quality of life at older ages? Examining the WHO ICF disability domains as mediators of this relationship.
|date=06.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29474988
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25209970
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2018.01.073
|full-text-url=https://sci-hub.do/10.1080/13607863.2014.955457
}}
}}
* {{medline-title
* {{medline-title
|title=Bioaccessibility of [[PAH]]s and [[PAH]] derivatives in a fuel soot assessed by an in vitro digestive model with absorptive sink: Effects of aging the soot in a soil-water mixture.
|title=Differential trajectories of well-being in older adult women: the role of optimism.
|date=15.02.2018
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28968578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25209994
|full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2017.09.227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483851
}}
}}
==TFAM==
==CLU==


* {{medline-title
* {{medline-title
|title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training.
|title=Expression of Clusterin suppresses Cr(VI)-induced premature senescence through activation of PI3K/AKT pathway.
|date=01.10.2019
|date=15.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31376806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2019.109465
}}
}}
* {{medline-title
* {{medline-title
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|title=Informative combination of [[CLU]] rs11136000, serum HDL levels, diabetes, and age as a new piece of puzzle-picture of predictive medicine for cognitive disorders.
|date=08.07.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30560405
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
|full-text-url=https://sci-hub.do/10.1007/s11033-018-4561-5
}}
}}
* {{medline-title
* {{medline-title
|title=Differences in Liver [[TFAM]] Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats.
|title=Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
|date=27.05.2019
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31137890
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566948
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354244
}}
}}
* {{medline-title
* {{medline-title
|title=Photobiomodulation and Coenzyme Q  Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=2019
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
* {{medline-title
* {{medline-title
|title=[A study on alterations in mitochondrial biological characteristics during cellular senescence of human embryonic lung fibroblasts].
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=06.03.2019
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30841673
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://sci-hub.do/10.3760/cma.j.issn.0253-9624.2019.03.014
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in Stemness Properties, Differentiation Potential, Oxidative Stress, Senescence and Mitochondrial Function in Wharton's Jelly Stem Cells of Umbilical Cords of Mothers with Gestational Diabetes Mellitus.
|title=Role of [[CLU]], [[PICALM]], and [[TNK1]] Genotypes in Aging With and Without Alzheimer's Disease.
|date=06.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30645713
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28631188
|full-text-url=https://sci-hub.do/10.1007/s12015-019-9872-y
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0547-x
}}
}}
* {{medline-title
* {{medline-title
|title=Cycling CD4+ T cells in HIV-infected immune nonresponders have mitochondrial dysfunction.
|title=Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study.
|date=01.11.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28269768
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205369
|full-text-url=https://sci-hub.do/10.3233/JAD-160774
}}
}}
* {{medline-title
* {{medline-title
|title=Increased [[TFAM]] binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart.
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=20.08.2018
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29969715
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
}}
* {{medline-title
* {{medline-title
|title=Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice.
|title=An Alzheimer's Disease Genetic Risk Score Predicts Longitudinal Thinning of Hippocampal Complex Subregions in Healthy Older Adults.
|date=08.2018
|date=05-06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29745022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27482534
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945997
}}
}}
* {{medline-title
* {{medline-title
|title=Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/[[PGC]]-1α pathway.
|title=Genetically-mediated Grey and White Matter Alteration in Normal Elderly Individuals with the [[CLU]]-C Allele Gene.
|date=02.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325933
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27396407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112753
}}
}}
* {{medline-title
* {{medline-title
|title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers.
|title=Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models.
|date=02.2018
|date=30.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27265785
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135662
}}
}}
* {{medline-title
* {{medline-title
|title=Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats.
|title=Risk-reducing Apolipoprotein E and Clusterin genotypes protect against the consequences of poor vascular health on executive function performance and change in nondemented older adults.
|date=11.2017
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807823
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27143425
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857019
}}
}}
==BRCA1==
* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Impact of [[PICALM]] and [[CLU]] on hippocampal degeneration.
|date=10.2019
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27017968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867347
}}
}}
* {{medline-title
* {{medline-title
|title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair.
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=06.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
}}
* {{medline-title
* {{medline-title
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|title=Apolipoprotein E and Clusterin can magnify effects of personality vulnerability on declarative memory performance in non-demented older adults.
|date=2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26343804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826141
}}
}}
* {{medline-title
* {{medline-title
|title=Klotho gene polymorphisms are associated with healthy aging and longevity: Evidence from a meta-analysis.
|title=Mesterolone treatment of aging male syndrome improves lower urinary tract symptoms.
|date=03.2019
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30633899
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25842579
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.12.003
 
}}
}}
* {{medline-title
* {{medline-title
|title=High expression of the breast cancer susceptibility gene [[BRCA1]] in long-lived termite kings.
|title=Combined effects of Alzheimer risk variants in the [[CLU]] and ApoE genes on ventricular expansion patterns in the elderly.
|date=11.10.2018
|date=07.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30312170
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24806679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012312
}}
}}
* {{medline-title
* {{medline-title
|title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment.
|title=The benefits of staying active in old age: physical activity counteracts the negative influence of [[PICALM]], [[BIN1]], and [[CLU]] risk alleles on episodic memory functioning.
|date=2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24660791
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527
|full-text-url=https://sci-hub.do/10.1037/a0035465
}}
}}
* {{medline-title
* {{medline-title
|title=Cost effectiveness of population based [[BRCA1]] founder mutation testing in Sephardi Jewish women.
|title=Age-dependent effect of Alzheimer's risk variant of [[CLU]] on EEG alpha rhythm in non-demented adults.
|date=04.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288066
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24379779
|full-text-url=https://sci-hub.do/10.1016/j.ajog.2017.12.221
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861782
}}
}}
==GDF15==
* {{medline-title
* {{medline-title
|title=Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions.
|title=Disease-specific plasma levels of mitokines FGF21, [[GDF15]], and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging.
|date=04.01.2018
|date=31.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249653
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33131010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756112
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00287-w
}}
}}
* {{medline-title
* {{medline-title
|title=Faulty [[BRCA1]], [[BRCA2]] genes: how poor is the prognosis?
|title=Growth differentiation factor 15 protects against the aging-mediated systemic inflammatory response in humans and mice.
|date=10.2017
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29017890
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32691494
|full-text-url=https://sci-hub.do/10.1016/j.annepidem.2017.09.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431835
}}
}}
* {{medline-title
* {{medline-title
|title=Ovarian Aging in Women With BRCA Germline Mutations.
|title=Analysis of Epigenetic Age Predictors in Pain-Related Conditions.
|date=01.10.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28938488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32582603
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296181
}}
}}
* {{medline-title
* {{medline-title
|title=The expected benefit of preventive mastectomy on breast cancer incidence and mortality in BRCA mutation carriers, by age at mastectomy.
|title=[[GDF15]] Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness.
|date=01.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28914396
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32477368
|full-text-url=https://sci-hub.do/10.1007/s10549-017-4476-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235447
}}
}}
==C2==
* {{medline-title
* {{medline-title
|title=[Effects of resistance training on mitochondrial function in skeletal muscle of aging rats].
|title=[[GDF15]] is an epithelial-derived biomarker of idiopathic pulmonary fibrosis.
|date=03.2020
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32744013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31432710
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5861.2020.037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842909
}}
}}
* {{medline-title
* {{medline-title
|title=Structural and functional characterization of Solanum lycopersicum phosphatidylinositol 3-kinase [[C2]] domain.
|title=Senescence-associated tissue microenvironment promotes colon cancer formation through the secretory factor [[GDF15]].
|date=03.2020
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31972387
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31389184
|full-text-url=https://sci-hub.do/10.1016/j.plaphy.2020.01.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826139
}}
}}
* {{medline-title
* {{medline-title
|title=Radiological and Clinical Outcomes of Anterior Cervical Discectomy and Fusion in Older Patients: A Comparative Analysis of Young-Old Patients (Ages 65-74 Years) and Middle-Old Patients (Over 75 Years).
|title=mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism.
|date=03.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31284342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30924297
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516169
}}
}}
* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=04.07.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related Changes in Cervical Sagittal Alignment: A Radiographic Analysis.
|title=Growth differentiation factor 15 ([[GDF15]]): A survival protein with therapeutic potential in metabolic diseases.
|date=01.10.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31261278
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790643
|full-text-url=https://sci-hub.do/10.1097/BRS.0000000000003082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196666
}}
}}
* {{medline-title
* {{medline-title
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.
|title=[The role of «Youth and aging proteins» in essential hypertension pathogenesis.]
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30584875
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829
 
}}
}}
* {{medline-title
* {{medline-title
|title=Twenty-year Longitudinal Follow-up MRI Study of Asymptomatic Volunteers: The Impact of Cervical Alignment on Disk Degeneration.
|title=A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup.
|date=12.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30151729
|full-text-url=https://sci-hub.do/10.1097/BSD.0000000000000706
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294728
}}
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
* {{medline-title
* {{medline-title
|title=Dialdehyde cellulose crosslinked poly(vinyl alcohol) hydrogels: Influence of catalyst and crosslinker shelf life.
|title=Plasma proteomic signature of age in healthy humans.
|date=15.10.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092989
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29992704
|full-text-url=https://sci-hub.do/10.1016/j.carbpol.2018.06.035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156492
}}
}}
* {{medline-title
* {{medline-title
|title=Trend-analysis of dental hard-tissue conditions as function of tooth age.
|title=Human Aging and Longevity Are Characterized by High Levels of Mitokines.
|date=07.2018
|date=23.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29800639
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955888
|full-text-url=https://sci-hub.do/10.1016/j.jdent.2018.05.011
|full-text-url=https://sci-hub.do/10.1093/gerona/gly153
}}
}}
* {{medline-title
* {{medline-title
|title=Attenuation of the Niemann-Pick type [[C2]] disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2.
|title=Induction of Growth Differentiation Factor 15 in Skeletal Muscle of Old Taurine Transporter Knockout Mouse.
|date=08.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29655638
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29491220
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2018.04.001
|full-text-url=https://sci-hub.do/10.1248/bpb.b17-00969
}}
}}
* {{medline-title
* {{medline-title
|title=Repurposing existing drugs for new AMPK activators as a strategy to extend lifespan: a computer-aided drug discovery study.
|title=Cigarette Smoke Induces Human Airway Epithelial Senescence via Growth Differentiation Factor 15 Production.
|date=04.2018
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29335817
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27093475
|full-text-url=https://sci-hub.do/10.1007/s10522-018-9744-x
|full-text-url=https://sci-hub.do/10.1165/rcmb.2015-0143OC
}}
}}
==CA2==
* {{medline-title
* {{medline-title
|title=Maintaining Aging Hippocampal Function with Safe and Feasible Shaking Exercise in SAMP10 Mice.
|title=Secreted growth differentiation factor 15 as a potential biomarker for mitochondrial dysfunctions in aging and age-related disorders.
|date=2020
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32526748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27018280
|full-text-url=https://sci-hub.do/10.1159/000507884
|full-text-url=https://sci-hub.do/10.1111/ggi.12724
}}
}}
* {{medline-title
* {{medline-title
|title=One-year Follow-up Study of Hippocampal Subfield Atrophy in Alzheimer's Disease and Normal Aging.
|title=[[GDF15]] contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells.
|date=2019
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32008518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26909594
|full-text-url=https://sci-hub.do/10.2174/1573405615666190327102052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891072
}}
}}
* {{medline-title
* {{medline-title
|title=Maturation of PNN and ErbB4 Signaling in Area [[CA2]] during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory.
|title=hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling.
|date=29.10.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665627
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25239873
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.09.044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169862
}}
}}
==MCC==
* {{medline-title
* {{medline-title
|title=Early disruption of parvalbumin expression and perineuronal nets in the hippocampus of the Tg2576 mouse model of Alzheimer's disease can be rescued by enriched environment.
|title=Multiple chronic conditions and risk of cognitive impairment and dementia among older Americans: findings from the Aging, Demographics, and Memory Study (ADAMS).
|date=12.2018
|date=07.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30273829
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32633198
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.08.024
|full-text-url=https://sci-hub.do/10.1080/13825585.2020.1790492
}}
}}
* {{medline-title
* {{medline-title
|title=Protracted hippocampal development is associated with age-related improvements in memory during early childhood.
|title=Behaviour consistency is a sensitive tool for distinguishing the effects of aging on physical activity.
|date=01.07.2018
|date=01.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518573
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32348871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949262
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2020.112619
}}
}}
* {{medline-title
* {{medline-title
|title=Neurodevelopment and behavior in neonatal OXYS rats with genetically determined accelerated senescence.
|title=Burden on Caregivers of Adults with Multiple Chronic Conditions: Intersectionality of Age, Gender, Education level, Employment Status, and Impact on Social Life.
|date=15.02.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29274882
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31475644
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2017.12.021
|full-text-url=https://sci-hub.do/10.1017/S071498081900045X
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Chronic Administration of Resveratrol on Cognitive Performance during Aging Process in Rats.
|title=Using the Technology Acceptance Model to Explore User Experience, Intent to Use, and Use Behavior of a Patient Portal Among Older Adults With Multiple Chronic Conditions: Descriptive Qualitative Study.
|date=2017
|date=08.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30958272
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475817
}}
}}
* {{medline-title
* {{medline-title
|title=Time of day but not aging regulates 5-HT  receptor binding sites in the hamster hippocampus.
|title=Trends in Risk of Limitations in Instrumental Activities of Daily Living Over Age in Older Persons With and Without Multiple Chronic Conditions.
|date=01.01.2018
|date=01.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29107707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30772903
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.10.057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909894
}}
}}
* {{medline-title
* {{medline-title
|title=Cytoarchitectonically-driven MRI atlas of nonhuman primate hippocampus: Preservation of subfield volumes in aging.
|title=Association between treatment of superficial bladder cancer and 10-year mortality in older adults with multiple chronic conditions.
|date=05.2019
|date=01.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29072793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30289971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920786
|full-text-url=https://sci-hub.do/10.1002/cncr.31705
}}
}}
* {{medline-title
* {{medline-title
|title=Hippocampal sclerosis, hippocampal neuron loss patterns and TDP-43 in the aged population.
|title=The AGING Initiative experience: a call for sustained support for team science networks.
|date=07.2018
|date=18.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28833898
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29776412
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099461
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960077
}}
}}
* {{medline-title
* {{medline-title
|title=Aging Does Not Affect Axon Initial Segment Structure and Somatic Localization of Tau Protein in Hippocampal Neurons of Fischer 344 Rats.
|title=Evidence on selection, optimization, and compensation strategies to optimize aging with multiple chronic conditions: A literature review.
|date=07-08.2017
|date=09-10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28785724
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29609993
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520750
|full-text-url=https://sci-hub.do/10.1016/j.gerinurse.2018.02.013
}}
}}
==CCL2==
* {{medline-title
* {{medline-title
|title=β1 Integrin regulates adult lung alveolar epithelial cell inflammation.
|title=Chronic disease burden predicts food insecurity among older adults.
|date=30.01.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31873073
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29388533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098727
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204426
}}
}}
* {{medline-title
* {{medline-title
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke.
|title=Differences Between Younger and Older US Adults With Multiple Chronic Conditions.
|date=07.2019
|date=07.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28880839
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590488
}}
}}
* {{medline-title
* {{medline-title
|title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]]  accompanied with pro-tumorigenic secretome.
|title=Prevalence, Correlates, and Time Trends of Multiple Chronic Conditions Among Israeli Adults: Estimates From the Israeli National Health Interview Survey, 2014-2015.
|date=01.08.2019
|date=10.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28796598
|full-text-url=https://sci-hub.do/10.1002/ijc.32153
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553352
}}
}}
* {{medline-title
* {{medline-title
|title=Isoflurane anesthesia impairs the expression of immune neuromodulators in the hippocampus of aged mice.
|title=Seed incorporation during vinification and its impact on chemical and organoleptic properties in Syzygium cumini wine.
|date=2018
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30571762
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28764054
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301699
|full-text-url=https://sci-hub.do/10.1016/j.foodchem.2017.05.160
}}
}}
* {{medline-title
* {{medline-title
|title=Melatonin and inflammation-Story of a double-edged blade.
|title=Research Priorities to Advance the Health and Health Care of Older Adults with Multiple Chronic Conditions.
|date=11.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28555750
|full-text-url=https://sci-hub.do/10.1111/jpi.12525
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507733
}}
}}
* {{medline-title
* {{medline-title
|title=Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis.
|title=The ACHRU-CPP versus usual care for older adults with type-2 diabetes and multiple chronic conditions and their family caregivers: study protocol for a randomized controlled trial.
|date=2018
|date=06.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025494
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28166816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294729
}}
}}
* {{medline-title
* {{medline-title
|title=Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age.
|title=Changes in Depressive Symptoms among Older Adults with Multiple Chronic Conditions: Role of Positive and Negative Social Support.
|date=09.2018
|date=26.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891542
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28035968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105902
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295267
}}
}}
* {{medline-title
* {{medline-title
|title=Infiltrating macrophages contribute to age-related neuroinflammation in C57/BL6 mice.
|title=Sex-specific effects of cytotoxic chemotherapy agents cyclophosphamide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus - an aging connection.
|date=07.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29758231
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27032448
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.05.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925823
}}
}}
* {{medline-title
* {{medline-title
|title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles.
|title=Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin.
|date=05.2018
|date=01.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26968767
|full-text-url=https://sci-hub.do/10.1620/tjem.245.29
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867354
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|title=Corrupt practices negatively influenced food security and live expectancy in developing countries.
|date=2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26090058
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458312
}}
}}
* {{medline-title
* {{medline-title
|title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort.
|title=Decision-making and cancer screening: a qualitative study of older adults with multiple chronic conditions.
|date=03.2018
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25544380
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006
|full-text-url=https://sci-hub.do/10.1016/j.jgo.2014.12.001
}}
}}
==CIT==
==MMP2==


* {{medline-title
* {{medline-title
|title=Effect of sex on aging-related decline of dopamine transporter in healthy subjects.
|title=Cellular retinoic acid binding protein-II expression and its potential role in skin aging.
|date=14.10.2020
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33052524
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888968
|full-text-url=https://sci-hub.do/10.1007/s12149-020-01538-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461173
}}
}}
* {{medline-title
* {{medline-title
|title=The Relationship Between the Striatal Dopaminergic Neuronal and Cognitive Function With Aging.
|title=[Effect of saponins extracted from Panax japonicas on inhibiting myocardial fibrosis by TGF-β1/Smad3 signaling pathway in aging rats].
|date=2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32184717
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30593247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058549
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180724.006
}}
}}
* {{medline-title
* {{medline-title
|title=Initial Dietary Protein Intake Influence Muscle Function Adaptations in Older Men and Women Following High-Intensity Interval Training Combined with Citrulline.
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|date=22.07.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31336654
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683270
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
}}
}}
* {{medline-title
* {{medline-title
|title=I-FP-[[CIT]] striatal binding ratios do not decrease significantly with age in older adults.
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|date=06.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30900103
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|full-text-url=https://sci-hub.do/10.1007/s12149-019-01352-x
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of High-Intensity Interval Training Combined with L-Citrulline Supplementation on Functional Capacities and Muscle Function in Dynapenic-Obese Older Adults.
|title=PM2.5 promotes abdominal aortic aneurysm formation in angiotensin Ⅱ-infused apoe-/- mice.
|date=17.12.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30562948
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29800919
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306942
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.04.107
}}
}}
* {{medline-title
* {{medline-title
|title=The Six-Item Cognitive Impairment Test Is Associated with Adverse Outcomes in Acutely Hospitalized Older Patients: A Prospective Cohort Study.
|title=Activation of DNA demethylases attenuates aging-associated arterial stiffening and hypertension.
|date=05-08.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30140275
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052484
}}
}}
* {{medline-title
* {{medline-title
|title=Dopaminergic imaging separates normal pressure hydrocephalus from its mimics.
|title=[[MMP2]]-[[A2M]] interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction.
|date=10.2018
|date=19.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30155736
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29464020
|full-text-url=https://sci-hub.do/10.1007/s00415-018-9029-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814160
}}
}}
* {{medline-title
* {{medline-title
|title=Lower Cognitive Function in Older Patients with Lower Muscle Strength and Muscle Mass.
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|date=2018
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29913450
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067649
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
}}
}}
* {{medline-title
* {{medline-title
|title=Citrulline counteracts overweight- and aging-related effects on adiponectin and leptin gene expression in rat white adipose tissue.
|title=Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1.
|date=2015
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632824
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866058
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889428
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2016.10.002
}}
}}
* {{medline-title
* {{medline-title
|title=Overcoming Barriers of Age to Enhance Efficacy of Cancer Immunotherapy: The Clout of the Extracellular Matrix.
|title=Secondhand Smoke Exposure Enhances Cardiac Fibrosis Effects on the Aging Rat Hearts.
|date=2018
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546043
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27713609
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052479
}}
}}
* {{medline-title
* {{medline-title
|title=Validation of the 6-Item Cognitive Impairment Test and the 4AT test for combined delirium and dementia screening in older Emergency Department attendees.
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|date=01.01.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28985260
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860384
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
}}
}}
==MCC==
* {{medline-title
* {{medline-title
|title=Multiple chronic conditions and risk of cognitive impairment and dementia among older Americans: findings from the Aging, Demographics, and Memory Study (ADAMS).
|title=Stimulation of cellular senescent processes, including secretory phenotypes and anti-oxidant responses, after androgen deprivation therapy in human prostate cancer.
|date=07.07.2020
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32633198
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329245
|full-text-url=https://sci-hub.do/10.1080/13825585.2020.1790492
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2016.06.007
}}
}}
* {{medline-title
* {{medline-title
|title=Behaviour consistency is a sensitive tool for distinguishing the effects of aging on physical activity.
|title=Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses.
|date=01.07.2020
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32348871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27288264
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2020.112619
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993333
}}
}}
* {{medline-title
* {{medline-title
|title=Burden on Caregivers of Adults with Multiple Chronic Conditions: Intersectionality of Age, Gender, Education level, Employment Status, and Impact on Social Life.
|title=Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model.
|date=09.2020
|date=01.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31475644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26940433
|full-text-url=https://sci-hub.do/10.1017/S071498081900045X
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892659
}}
}}
* {{medline-title
* {{medline-title
|title=Using the Technology Acceptance Model to Explore User Experience, Intent to Use, and Use Behavior of a Patient Portal Among Older Adults With Multiple Chronic Conditions: Descriptive Qualitative Study.
|title=Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition.
|date=08.04.2019
|date=06.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30958272
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26400086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475817
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646369
}}
}}
* {{medline-title
* {{medline-title
|title=Trends in Risk of Limitations in Instrumental Activities of Daily Living Over Age in Older Persons With and Without Multiple Chronic Conditions.
|title=Fat and Sucrose Intake Induces Obesity-Related Bone Metabolism Disturbances: Kinetic and Reversibility Studies in Growing and Adult Rats.
|date=01.01.2020
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30772903
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26175082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909894
|full-text-url=https://sci-hub.do/10.1002/jbmr.2596
}}
}}
* {{medline-title
* {{medline-title
|title=Association between treatment of superficial bladder cancer and 10-year mortality in older adults with multiple chronic conditions.
|title=Differential levels of cathepsin B and L in serum between young and aged healthy people and their association with matrix metalloproteinase 2.
|date=01.12.2018
|date=09-10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30289971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25991043
|full-text-url=https://sci-hub.do/10.1002/cncr.31705
|full-text-url=https://sci-hub.do/10.1016/j.archger.2015.04.010
}}
}}
* {{medline-title
* {{medline-title
|title=The AGING Initiative experience: a call for sustained support for team science networks.
|title=[The expression of differential and matrix remodelling factors in human buccal epithelium in aging].
|date=18.05.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29776412
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640689
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960077
 
}}
}}
* {{medline-title
* {{medline-title
|title=Evidence on selection, optimization, and compensation strategies to optimize aging with multiple chronic conditions: A literature review.
|title=Metzincins and related genes in experimental renal ageing: towards a unifying fibrosis classifier across species.
|date=09-10.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29609993
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24569495
|full-text-url=https://sci-hub.do/10.1016/j.gerinurse.2018.02.013
|full-text-url=https://sci-hub.do/10.1093/ndt/gfu027
}}
}}
==NAMPT==
* {{medline-title
* {{medline-title
|title=Chronic disease burden predicts food insecurity among older adults.
|title=Over-expression of Nicotinamide phosphoribosyltransferase in mouse cells confers protective effect against oxidative and ER stress-induced premature senescence.
|date=06.2018
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29388533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32533606
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204426
|full-text-url=https://sci-hub.do/10.1111/gtc.12794
}}
}}
* {{medline-title
* {{medline-title
|title=Differences Between Younger and Older US Adults With Multiple Chronic Conditions.
|title=Resistance training increases muscle NAD  and NADH concentrations as well as [[NAMPT]] protein levels and global sirtuin activity in middle-aged, overweight, untrained individuals.
|date=07.09.2017
|date=05.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28880839
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32369778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288928
}}
}}
* {{medline-title
* {{medline-title
|title=Prevalence, Correlates, and Time Trends of Multiple Chronic Conditions Among Israeli Adults: Estimates From the Israeli National Health Interview Survey, 2014-2015.
|title=Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase ([[NAMPT]]) and Sirtuin-1 (SIRT-1) Pathway in Obesity and T2DM: Modulation by Metformin and Macronutrient Intake.
|date=10.08.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28796598
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920356
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938199
}}
}}
==PRL==
* {{medline-title
* {{medline-title
|title=Mechanism of [[PRL]]2 phosphatase-mediated PTEN degradation and tumorigenesis.
|title=Aerobic and resistance exercise training reverses age-dependent decline in NAD  salvage capacity in human skeletal muscle.
|date=25.08.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32788364
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31207144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456095
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6577427
}}
}}
* {{medline-title
* {{medline-title
|title=Prolactin mitigates deficiencies of retinal function associated with aging.
|title=Extracellular Vesicle-Contained e[[NAMPT]] Delays Aging and Extends Lifespan in Mice.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31698287
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.10.002
}}
* {{medline-title
|title=A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation.
|date=06.08.2019
|date=06.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31390566
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31204283
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687560
}}
}}
* {{medline-title
* {{medline-title
|title=IGF-1 Gene Therapy as a Potentially Useful Therapy for Spontaneous Prolactinomas in Senile Rats.
|title=lncRNA GAS5/miR-223/[[NAMPT]] axis modulates the cell proliferation and senescence of endothelial progenitor cells through PI3K/AKT signaling.
|date=2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30198429
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026096
|full-text-url=https://sci-hub.do/10.2174/1566523218666180905170020
|full-text-url=https://sci-hub.do/10.1002/jcb.28713
}}
}}
* {{medline-title
* {{medline-title
|title=Assessment of semen quality and fertility in young growing beef bulls exposed to ergot alkaloids.
|title=Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training.
|date=15.09.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29945053
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283350
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2018.06.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156423
}}
}}
* {{medline-title
* {{medline-title
|title=[Dynamic changes of reproductive hormone levels and related factors in old and middleaged men in health examination].
|title=Loss of [[NAMPT]] in aging retinal pigment epithelium reduces NAD  availability and promotes cellular senescence.
|date=02.2017
|date=12.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29658250
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905535
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046249
}}
}}
* {{medline-title
* {{medline-title
|title=Prolactin as a candidate sebotrop(h)ic hormone?
|title=Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating [[SIRT1]] activity and antioxidant gene expression in mouse cells.
|date=07.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29582473
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29178516
|full-text-url=https://sci-hub.do/10.1111/exd.13545
|full-text-url=https://sci-hub.do/10.1111/gtc.12542
}}
}}
* {{medline-title
* {{medline-title
|title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age.
|title=Deletion of Nampt in Projection Neurons of Adult Mice Leads to Motor Dysfunction, Neurodegeneration, and Death.
|date=04.2018
|date=29.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854367
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021762
}}
}}
* {{medline-title
* {{medline-title
|title=Chemogenetic Excitation of Accumbens-Projecting Infralimbic Cortical Neurons Blocks Toluene-Induced Conditioned Place Preference.
|title=Nicotinamide Phosphoribosyltransferase in Smooth Muscle Cells Maintains Genome Integrity, Resists Aortic Medial Degeneration, and Is Suppressed in Human Thoracic Aortic Aneurysm Disease.
|date=07.02.2018
|date=09.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29317484
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815347
|full-text-url=https://sci-hub.do/10.1161/CIRCRESAHA.116.310022
}}
}}
* {{medline-title
* {{medline-title
|title=[Analysis of serum reproductive hormone levels in men with hyperlipemia in the urban area of Shijiazhuang].
|title=Effect of lifelong football training on the expression of muscle molecular markers involved in healthy longevity.
|date=11.2016
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29281203
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28251397
 
|full-text-url=https://sci-hub.do/10.1007/s00421-017-3562-8
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Aging and caloric restriction impact adipose tissue, adiponectin, and circulating lipids.
|date=02.2018
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28156058
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418198
}}
}}
==TET2==
* {{medline-title
* {{medline-title
|title=Non-coding and Loss-of-Function Coding Variants in [[TET2]] are Associated with Multiple Neurodegenerative Diseases.
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells.
|date=07.05.2020
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32330418
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212268
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853
}}
}}
* {{medline-title
* {{medline-title
|title=60 Years of clonal hematopoiesis research: From X-chromosome inactivation studies to the identification of driver mutations.
|title=[[NAMPT]] regulates senescence, proliferation, and migration of endothelial progenitor cells through the [[SIRT1]] AS lncRNA/miR-22/[[SIRT1]] pathway.
|date=03.2020
|date=23.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32001340
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27569277
|full-text-url=https://sci-hub.do/10.1016/j.exphem.2020.01.008
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.08.133
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways.
|title=Hepatic NAD( ) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing.
|date=16.12.2019
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31842975
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27174364
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945761
}}
}}
* {{medline-title
* {{medline-title
|title=Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease.
|title=Targeting Nicotinamide Phosphoribosyltransferase as a Potential Therapeutic Strategy to Restore Adult Neurogenesis.
|date=03.2020
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31406340
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27018006
|full-text-url=https://sci-hub.do/10.1038/s41569-019-0247-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492912
}}
}}
* {{medline-title
* {{medline-title
|title=Targeted, Amplicon-Based, Next-Generation Sequencing to Detect Age-Related Clonal Hematopoiesis.
|title=A critical role of nicotinamide phosphoribosyltransferase in human telomerase reverse transcriptase induction by resveratrol in aortic smooth muscle cells.
|date=2019
|date=10.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30941718
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25926556
|full-text-url=https://sci-hub.do/10.1007/7651_2019_216
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484421
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|title=Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons.
|date=02.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24655393
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116450
}}
}}
==SST==
* {{medline-title
* {{medline-title
|title=Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development.
|title=The distance to death perceptions of older adults explain why they age in place: A theoretical examination.
|date=06.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30417440
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32972627
|full-text-url=https://sci-hub.do/10.1002/jcp.27752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489887
}}
}}
* {{medline-title
* {{medline-title
|title=Concise Review: Age-Related Clonal Hematopoiesis: Stem Cells Tempting the Devil.
|title=Population Segmentation Based on Healthcare Needs: Validation of a Brief Clinician-Administered Tool.
|date=09.2018
|date=30.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32607929
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125185
|full-text-url=https://sci-hub.do/10.1007/s11606-020-05962-4
}}
}}
* {{medline-title
* {{medline-title
|title=Hippocampal [i]TET1[/i] and [i][[TET2]][/i] Expression and DNA Hydroxymethylation Are Affected by Physical Exercise in Aged Mice.
|title=Examination on how emotion regulation mediates the relationship between future time perspective and well-being: a counter-evidence to the socioemotional selectivity theory.
|date=2018
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29732371
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922180
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040126
}}
}}
* {{medline-title
* {{medline-title
|title=An inflammatory environment containing TNFα favors Tet2-mutant clonal hematopoiesis.
|title=Shear-Wave and Strain Ultrasound Elastography of the Supraspinatus and Infraspinatus Tendons in Patients with Idiopathic Adhesive Capsulitis of the Shoulder: A Prospective Case-Control Study.
|date=03.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31270981
|full-text-url=https://sci-hub.do/10.1016/j.exphem.2017.11.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609436
}}
* {{medline-title
|title=Counting down while time flies: implications of age-related time acceleration for goal pursuit across adulthood.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048830
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436994
}}
}}
* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=Relative costs and benefits of alternative reproductive phenotypes at different temperatures - genotype-by-environment interactions in a sexually selected trait.
|date=2017
|date=11.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29996775
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042425
}}
}}
==TREM2==
* {{medline-title
* {{medline-title
|title=Loss of [[TREM2]] Confers Resilience to Synaptic and Cognitive Impairment in Aged Mice.
|title=Climate change and functional traits affect population dynamics of a long-lived seabird.
|date=09.12.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33139402
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29931768
|full-text-url=https://sci-hub.do/10.1523/JNEUROSCI.2193-20.2020
|full-text-url=https://sci-hub.do/10.1111/1365-2656.12827
}}
}}
* {{medline-title
* {{medline-title
|title=Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer's Disease Brain.
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography.
|date=2020
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33101276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546799
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0
}}
}}
* {{medline-title
* {{medline-title
|title=Knockdown of astrocytic [[TREM2]] in the hippocampus relieves cognitive decline in elderly male mice.
|title=The roles of chronological age and time perspective in memory positivity.
|date=15.01.2021
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32991925
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28728468
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2020.112939
|full-text-url=https://sci-hub.do/10.1080/13825585.2017.1356262
}}
}}
* {{medline-title
* {{medline-title
|title=Immune Signaling in Neurodegeneration.
|title=Atypical Red Blood Cells Are Prevalent in California Sea Lion Pups Born during Anomalous Sea Surface Temperature Events.
|date=16.04.2019
|date=09-10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30995509
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671858
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822103
|full-text-url=https://sci-hub.do/10.1086/692919
}}
}}
* {{medline-title
* {{medline-title
|title=The Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) as Expression of the Relationship between Microglia and Alzheimer's Disease: A Novel Marker for a Promising Pathway to Explore.
|title=DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers.
|date=2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30997915
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28419903
|full-text-url=https://sci-hub.do/10.14283/jfa.2018.43
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.04.006
}}
}}
* {{medline-title
* {{medline-title
|title=[[TREM2]] triggers microglial density and age-related neuronal loss.
|title=Sleep/wake movement velocities, trajectories and micro-arousals during maturation in rats.
|date=03.2019
|date=07.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548312
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28173758
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297220
}}
}}
* {{medline-title
* {{medline-title
|title=Differential effects of partial and complete loss of [[TREM2]] on microglial injury response and tauopathy.
|title=When meaning matters more: Media preferences across the adult life span.
|date=02.10.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30232263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27213487
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176614
|full-text-url=https://sci-hub.do/10.1037/pag0000098
}}
}}
* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=An improved spatial span test of visuospatial memory.
|date=16.08.2019
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26357906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://sci-hub.do/10.1080/09658211.2015.1076849
}}
}}
* {{medline-title
* {{medline-title
|title=Differential Phagocytic Properties of CD45  Microglia and CD45  Brain Mononuclear Phagocytes-Activation and Age-Related Effects.
|title=Hypermethylation of [[BDNF]] and [[SST]] Genes in the Orbital Frontal Cortex of Older Individuals: A Putative Mechanism for Declining Gene Expression with Age.
|date=2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29552013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25881116
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840283
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569950
}}
}}
* {{medline-title
* {{medline-title
|title=Microglia and Aging: The Role of the [[TREM2]]-DAP12 and [[CX3CL1]]-[[CX3CR1]] Axes.
|title=Sleep/Wake Dynamics Changes during Maturation in Rats.
|date=22.01.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29361745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25894573
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796261
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404317
}}
}}
* {{medline-title
* {{medline-title
|title=A Tale of Two Genes: Microglial Apoe and Trem2.
|title=Sleep disturbance associated with rotator cuff tear: correction with arthroscopic rotator cuff repair.
|date=19.09.2017
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28930654
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25776185
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2017.08.015
|full-text-url=https://sci-hub.do/10.1177/0363546515572769
}}
}}
==BACE1==
* {{medline-title
* {{medline-title
|title=Electric Stimulation of Neurogenesis Improves Behavioral Recovery After Focal Ischemia in Aged Rats.
|title=A cortical disinhibitory circuit for enhancing adult plasticity.
|date=2020
|date=27.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32742258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25626167
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365235
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337686
}}
}}
* {{medline-title
* {{medline-title
|title=Disruption of synaptic expression pattern and age-related DNA oxidation in a neuronal model of lead-induced toxicity.
|title=Telemetry and random-walk models reveal complex patterns of partial migration in a large marine predator.
|date=05.2020
|date=11.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32058320
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24400511
|full-text-url=https://sci-hub.do/10.1016/j.etap.2020.103350
|full-text-url=https://sci-hub.do/10.1890/12-2014.1
}}
}}
==UCP1==
* {{medline-title
* {{medline-title
|title=Age- and sex-dependent profiles of [[APP]] fragments and key secretases align with changes in despair-like behavior and cognition in young [[APP]]Swe/Ind mice.
|title=Muscle-dependent regulation of adipose tissue function in long-lived growth hormone-mutant mice.
|date=02.04.2019
|date=28.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30803762
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32464603
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.02.083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288969
}}
}}
* {{medline-title
* {{medline-title
|title=Selective reduction of [[APP]]-[[BACE1]] activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PD[[APP]] mice.
|title=Lack of [[UCP1]] stimulates fatty liver but mediates [[UCP1]]-independent action of beige fat to improve hyperlipidemia in Apoe knockout mice.
|date=03.2019
|date=01.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30572184
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32179129
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357873
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165762
}}
}}
* {{medline-title
* {{medline-title
|title=Temporal Effects of Neuron-specific beta-secretase 1 ([[BACE1]]) Knock-in on the Mouse Brain Metabolome: Implications for Alzheimer's Disease.
|title=Postnatal leptin surge is critical for the transient induction of the developmental beige adipocytes in mice.
|date=15.01.2019
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30496823
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31961706
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.11.031
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191411
}}
}}
* {{medline-title
* {{medline-title
|title=Removal of p75 Neurotrophin Receptor Expression from Cholinergic Basal Forebrain Neurons Reduces Amyloid-β Plaque Deposition and Cognitive Impairment in Aged APP/PS1 Mice.
|title=Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice.
|date=07.2019
|date=05.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30374941
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31806023
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1404-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896328
}}
}}
* {{medline-title
* {{medline-title
|title=Axonal organization defects in the hippocampus of adult conditional [[BACE1]] knockout mice.
|title=An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise.
|date=19.09.2018
|date=19.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30232227
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31427677
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aao5620
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700172
}}
}}
* {{medline-title
* {{medline-title
|title=Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease.
|title=Brown and Beige Adipose Tissue and Aging.
|date=10.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29981845
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31281288
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.07.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595248
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells.
|title=Resveratrol and HIV-protease inhibitors control [[UCP1]] expression through opposite effects on p38 MAPK phosphorylation in human adipocytes.
|date=15.01.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29348391
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31294462
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811245
|full-text-url=https://sci-hub.do/10.1002/jcp.29032
}}
}}
* {{medline-title
* {{medline-title
|title=Neuroprotective potential of high-dose biotin.
|title=Circulating factors present in the sera of naturally skinny people may influence cell commitment and adipocyte differentiation of mesenchymal stromal cells.
|date=11.2017
|date=26.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29150274
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30949296
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2017.10.012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441938
}}
}}
==CD40==
* {{medline-title
* {{medline-title
|title=The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy.
|title=Assessment of the Aging of the Brown Adipose Tissue by F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna .
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30560130
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079616
}}
* {{medline-title
|title=Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29903737
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092113
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Changes on [[CD40]] Promotor Methylation and Immune Gene Expressions in Thymus of Chicken.
|title=Rapamycin Reverses Metabolic Deficits in Lamin A/C-Deficient Mice.
|date=2018
|date=06.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30519246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27926859
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259354
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594831
}}
}}
* {{medline-title
* {{medline-title
|title=Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia.
|title=Targeted mitochondrial uncoupling beyond [[UCP1]] - The fine line between death and metabolic health.
|date=2018
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30459812
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27916644
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232269
|full-text-url=https://sci-hub.do/10.1016/j.biochi.2016.11.013
}}
}}
* {{medline-title
* {{medline-title
|title=One-Year Consumption of a Mediterranean-Like Dietary Pattern With Vitamin D3 Supplements Induced Small Scale but Extensive Changes of Immune Cell Phenotype, Co-receptor Expression and Innate Immune Responses in Healthy Elderly Subjects: Results From the United Kingdom Arm of the NU-AGE Trial.
|title=Methionine restriction improves renal insulin signalling in aged kidneys.
|date=2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30093866
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27453066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070774
|full-text-url=https://sci-hub.do/10.1016/j.mad.2016.07.003
}}
}}
* {{medline-title
* {{medline-title
|title=Membrane-Bound [[CD40]]L Promotes Senescence and Initiates Senescence-Associated Secretory Phenotype via NF-κB Activation in Lung Adenocarcinoma.
|title=Age-related changes of serum mitochondrial uncoupling 1, rumen and rectal temperature in goats.
|date=2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30078020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27264887
|full-text-url=https://sci-hub.do/10.1159/000492352
|full-text-url=https://sci-hub.do/10.1016/j.jtherbio.2016.05.002
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Immunosenescence on the Lower Expression of Surface Molecules in Neutrophils and Lymphocytes.
|title=Sestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose Tissue.
|date=2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29866027
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26257706
|full-text-url=https://sci-hub.do/10.2174/1874609811666180605092234
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513567
}}
}}
* {{medline-title
* {{medline-title
|title=Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice.
|title=[The role of uncoupling proteins in mechanisms of protection from oxidative stress].
|date=2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26040041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757150
|full-text-url=https://sci-hub.do/10.15407/fz61.01.091
}}
}}
* {{medline-title
* {{medline-title
|title=Elderly dendritic cells respond to LPS/IFN-γ and [[CD40]]L stimulation despite incomplete maturation.
|title=Miglitol protects against age-dependent weight gain in mice: A potential role of increased U[[CP]]1 content in brown adipose tissue.
|date=2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29652910
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25833077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898732
|full-text-url=https://sci-hub.do/10.1507/endocrj.EJ15-0116
}}
}}
* {{medline-title
* {{medline-title
|title=C-Reactive Protein Impairs Dendritic Cell Development, Maturation, and Function: Implications for Peripheral Tolerance.
|title=Shc depletion stimulates brown fat activity in vivo and in vitro.
|date=2018
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29556231
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25257068
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244234
}}
}}
* {{medline-title
* {{medline-title
|title=Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin-utrophin double knockout mice.
|title=Inducible brown adipocytes in subcutaneous inguinal white fat: the role of continuous sympathetic stimulation.
|date=12.2017
|date=01.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29255177
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25184993
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216946
}}
}}
==CXCR4==
==CDKN1A==


* {{medline-title
* {{medline-title
|title=Aging-Related Reduced Expression of [[CXCR4]] on Bone Marrow Mesenchymal Stromal Cells Contributes to Hematopoietic Stem and Progenitor Cell Defects.
|title=Involvement of [[CDKN1A]] (p21) in cellular senescence in response to heat and irradiation stress during preimplantation development.
|date=08.2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32418119
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32253738
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395885
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193008
}}
}}
* {{medline-title
* {{medline-title
|title=Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/[[CXCR4]] signalling pathway.
|title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells.
|date=09.2020
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32384208
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244
|full-text-url=https://sci-hub.do/10.1002/ejhf.1840
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023
}}
}}
* {{medline-title
* {{medline-title
|title=Stromal Cell-Derived Factor 1 Protects Brain Vascular Endothelial Cells from Radiation-Induced Brain Damage.
|title=Histone demethylase [[KDM6B]] regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells.
|date=10.10.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31658727
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30825201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830118
|full-text-url=https://sci-hub.do/10.1002/jcp.28431
}}
}}
* {{medline-title
* {{medline-title
|title=A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|date=19.02.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30709741
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2019.01.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
}}
}}
* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Altered modulation of lamin A/C-[[HDAC2]] interaction and p21 expression during oxidative stress response in HGPS.
|date=15.11.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30109767
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156291
}}
}}
* {{medline-title
* {{medline-title
|title=Reducing [[CXCR4]] Resulted in Impairing Proliferation and Promoting Aging.
|title=Conditioned medium from stimulated macrophages inhibits growth but induces an inflammatory phenotype in breast cancer cells.
|date=2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30080220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966967
|full-text-url=https://sci-hub.do/10.1007/s12603-018-1013-9
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.06.126
}}
}}
* {{medline-title
* {{medline-title
|title=Targeting junctional adhesion molecule-C ameliorates sepsis-induced acute lung injury by decreasing [[CXCR4]]  aged neutrophils.
|title=DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice.
|date=12.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088666
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258282
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877805
}}
}}
* {{medline-title
* {{medline-title
|title=Tumor microenvironment in functional adrenocortical adenomas: immune cell infiltration in cortisol-producing adrenocortical adenoma.
|title=Cellular Senescence in Mouse Hippocampus After Irradiation and the Role of p53 and p21.
|date=07.2018
|date=01.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596893
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28340115
|full-text-url=https://sci-hub.do/10.1016/j.humpath.2018.03.016
|full-text-url=https://sci-hub.do/10.1093/jnen/nlx006
}}
}}
* {{medline-title
* {{medline-title
|title=Lower resting and exercise-induced circulating angiogenic progenitors and angiogenic T cells in older men.
|title=p16  enhances the transcriptional and the apoptotic functions of p53 through DNA-dependent interaction.
|date=01.03.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167123
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28218424
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00592.2017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266037
}}
}}
* {{medline-title
* {{medline-title
|title=Adipose-Derived Mesenchymal Stem Cells from the Elderly Exhibit Decreased Migration and Differentiation Abilities with Senescent Properties.
|title=Establishment and application of a novel patient-derived KIAA1549:[[BRAF]]-driven pediatric pilocytic astrocytoma model for preclinical drug testing.
|date=09.2017
|date=14.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29113467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28002790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680952
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355278
}}
}}
==ERG==
* {{medline-title
* {{medline-title
|title=Effect of age and sex on neurodevelopment and neurodegeneration in the healthy eye: Longitudinal functional and structural study in the Long-Evans rat.
|title=Phosphorylation of [[MITF]] by AKT affects its downstream targets and causes [[TP53]]-dependent cell senescence.
|date=11.2020
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32882213
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27702651
|full-text-url=https://sci-hub.do/10.1016/j.exer.2020.108208
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2016.09.029
}}
}}
* {{medline-title
* {{medline-title
|title=Mice With a Combined Deficiency of Superoxide Dismutase 1 (Sod1), DJ-1 (Park7), and Parkin (Prkn) Develop Spontaneous Retinal Degeneration With Aging.
|title=Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus.
|date=03.09.2019
|date=18.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31487745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26809688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871660
}}
}}
* {{medline-title
* {{medline-title
|title=Test-retest repeatability of the pattern electroretinogram and flicker electroretinogram.
|title=Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence.
|date=12.2019
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31312944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802937
|full-text-url=https://sci-hub.do/10.1007/s10633-019-09707-5
|full-text-url=https://sci-hub.do/10.1016/j.plefa.2015.10.006
}}
}}
* {{medline-title
* {{medline-title
|title=Regeneration of Dopaminergic Neurons in Adult Zebrafish Depends on Immune System Activation and Differs for Distinct Populations.
|title=TP53inp1 Gene Is Implicated in Early Radiation Response in Human Fibroblast Cells.
|date=12.06.2019
|date=23.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30948475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26512655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632809
}}
}}
* {{medline-title
* {{medline-title
|title=Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
|title=Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium.
|date=01.05.2019
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735837
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25963977
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.02.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450138
}}
}}
* {{medline-title
* {{medline-title
|title=Further Characterization of the Predominant Inner Retinal Degeneration of Aging Cln3  Knock-In Mice.
|title=Tocotrienol-rich fraction prevents cellular aging by modulating cell proliferation signaling pathways.
|date=2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29721970
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25945449
|full-text-url=https://sci-hub.do/10.1007/978-3-319-75402-4_50
|full-text-url=https://sci-hub.do/10.7417/CT.2015.1825
}}
}}
* {{medline-title
* {{medline-title
|title=Two novel forms of [[ERG]] oscillation in Drosophila: age and activity dependence.
|title=Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of the [[CDKN1A]] (p21(WAF1) (/) (CIP1) ) and SIRT1 genes.
|date=03-06.2018
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29688104
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25557355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233714
|full-text-url=https://sci-hub.do/10.1002/path.4505
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of [[XBP1]] accelerates age-related decline in retinal function and neurodegeneration.
|title=Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease.
|date=04.04.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24626178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883257
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050146
}}
}}
==DNMT1==
* {{medline-title
* {{medline-title
|title=The Complement System Is Critical in Maintaining Retinal Integrity during Aging.
|title=DNA Methyltransferase 1 ([[DNMT1]]) Function Is Implicated in the Age-Related Loss of Cortical Interneurons.
|date=2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29497373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793592
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818470
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387673
}}
}}
* {{medline-title
* {{medline-title
|title=EDI OCT evaluation of choroidal thickness in Stargardt disease.
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|date=2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304098
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755895
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
}}
}}
==F3==
* {{medline-title
* {{medline-title
|title=A Comprehensive Analysis of Age and Gender Effects in European Portuguese Oral Vowels.
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
|date=05.12.2020
|date=05.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33293174
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939
|full-text-url=https://sci-hub.do/10.1016/j.jvoice.2020.10.021
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005
}}
}}
* {{medline-title
* {{medline-title
|title=Prenatal exposure to an environmentally relevant phthalate mixture accelerates biomarkers of reproductive aging in a multiple and transgenerational manner in female mice.
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells.
|date=28.10.2020
|date=15.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33129917
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2020.10.009
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031
}}
}}
* {{medline-title
* {{medline-title
|title=Combining Frontal Transcranial Direct Current Stimulation With Walking Rehabilitation to Enhance Mobility and Executive Function: A Pilot Clinical Trial.
|title=Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating [[DNMT1]] via [[ZEB1]].
|date=18.08.2020
|date=16.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32808403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29466247
|full-text-url=https://sci-hub.do/10.1111/ner.13250
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842848
}}
}}
* {{medline-title
* {{medline-title
|title=Multigenerational exposure to TiO  nanoparticles in soil stimulates stress resistance and longevity of survived C. elegans via activating insulin/IGF-like signaling.
|title=Microrna-217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1.
|date=08.2020
|date=16.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32203849
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28380423
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2020.114376
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464883
}}
}}
* {{medline-title
* {{medline-title
|title=Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice.
|title=A positive feedback loop between Pim-1 kinase and [[HBP1]] transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis.
|date=12.09.2019
|date=19.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31514170
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28348080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781998
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437229
}}
}}
* {{medline-title
* {{medline-title
|title=Transgenerational Effects of Extended Dauer Diapause on Starvation Survival and Gene Expression Plasticity in [i]Caenorhabditis elegans[/i].
|title=miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1.
|date=09.2018
|date=09.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30049782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28277545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116965
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386568
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of Supplemental Protein on the Life Expectancy and Reproduction of the Chinese Citrus Fruit Fly, Bactrocera minax (Enderlein) (Tetradacus minax) (Diptera: Tephritidae).
|title=Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.
|date=01.03.2018
|date=07.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28215845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358097
}}
}}
* {{medline-title
* {{medline-title
|title=Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice.
|title=The Ubiquitin-like with PHD and Ring Finger Domains 1 ([[UHRF1]])/DNA Methyltransferase 1 ([[DNMT1]]) Axis Is a Primary Regulator of Cell Senescence.
|date=14.03.2018
|date=03.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540228
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28100769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339756
}}
}}
* {{medline-title
* {{medline-title
|title=Multigenerational effects of 4-methylbenzylidene camphor (4-MBC) on the survival, development and reproduction of the marine copepod Tigriopus japonicus.
|title=Short term methionine restriction increases hepatic global DNA methylation in adult but not young male C57BL/6J mice.
|date=01.2018
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172130
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27940170
|full-text-url=https://sci-hub.do/10.1016/j.aquatox.2017.11.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906125
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Aging on Vocal Fundamental Frequency and Vowel Formants in Men and Women.
|title=In vivo and in silico studies to identify mechanisms associated with Nurr1 modulation following early life exposure to permethrin in rats.
|date=09.2018
|date=06.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28864082
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27826104
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832520
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2016.10.071
}}
}}
==GAL==
* {{medline-title
* {{medline-title
|title=Overexpression of Pitx1 attenuates the senescence of chondrocytes from osteoarthritis degeneration cartilage-A self-controlled model for studying the etiology and treatment of osteoarthritis.
|title=Age-Related Changes in DNA Methylation Associated with Shifting Th1/Th2 Balance.
|date=02.2020
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783149
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27650651
|full-text-url=https://sci-hub.do/10.1016/j.bone.2019.115177
|full-text-url=https://sci-hub.do/10.1007/s10753-016-0425-0
}}
}}
* {{medline-title
* {{medline-title
|title=β-Caryophyllene Reduces DNA Oxidation and the Overexpression of Glial Fibrillary Acidic Protein in the Prefrontal Cortex and Hippocampus of d-Galactose-Induced Aged BALB/c Mice.
|title=[[CDK4]]-[[CDK6]] inhibitors induce autophagy-mediated degradation of [[DNMT1]] and facilitate the senescence antitumor response.
|date=05.2020
|date=02.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31663807
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27532423
|full-text-url=https://sci-hub.do/10.1089/jmf.2019.0111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079664
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence-associated β-galactosidase activity in the developing avian retina.
|title=Developmental lead exposure and lifespan alterations in epigenetic regulators and their correspondence to biomarkers of Alzheimer's disease.
|date=09.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31226225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27239543
|full-text-url=https://sci-hub.do/10.1002/dvdy.74
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879653
}}
}}
* {{medline-title
* {{medline-title
|title=Zeaxanthin Isolated from [i]Dunaliella salina[/i] Microalgae Ameliorates Age Associated Cardiac Dysfunction in Rats through Stimulation of Retinoid Receptors.
|title=Age-dependent expression of [[DNMT1]] and [[DNMT3B]] in PBMCs from a large European population enrolled in the MARK-AGE study.
|date=14.05.2019
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31091726
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27169697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562725
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933658
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway.
|title=[[SIRT1]] affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing.
|date=15.07.2019
|date=24.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039346
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26104761
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2019.04.043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480908
}}
}}
* {{medline-title
* {{medline-title
|title=[[MYC]] and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts.
|title=The Interplay Between miR-148a and [[DNMT1]] Might be Exploited for Pancreatic Cancer Therapy.
|date=2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526305
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25950085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343716
|full-text-url=https://sci-hub.do/10.3109/07357907.2015.1025794
}}
}}
==DNMT3A==
* {{medline-title
* {{medline-title
|title=Manipulation of molecular pathways and senescence hallmarks by natural compounds in fibroblast cells.
|title=Epigenetic regulation of miR-29a/miR-30c/[[DNMT3A]] axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells.
|date=04.2019
|date=09.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30474871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32961441
|full-text-url=https://sci-hub.do/10.1002/jcb.27909
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509080
}}
}}
* {{medline-title
* {{medline-title
|title=Ellagic acid reveals promising anti-aging effects against d-galactose-induced aging on human neuroblastoma cell line, SH-SY5Y: A mechanistic study.
|title=Collagens and DNA methyltransferases in mare endometrosis.
|date=12.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30372874
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31512314
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.10.024
|full-text-url=https://sci-hub.do/10.1111/rda.13515
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular and biochemical evidence on the protective role of ellagic acid and silybin against oxidative stress-induced cellular aging.
|title=Age-related clonal haemopoiesis is associated with increased epigenetic age.
|date=04.2018
|date=19.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28887692
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31430471
|full-text-url=https://sci-hub.do/10.1007/s11010-017-3172-0
|full-text-url=https://sci-hub.do/10.1016/j.cub.2019.07.011
}}
}}
* {{medline-title
* {{medline-title
|title=Hyperphosphatemia induces senescence in human endothelial cells by increasing endothelin-1 production.
|title=Alcohol Extracts From [i]Ganoderma lucidum[/i] Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents.
|date=12.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28857396
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971923
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444160
}}
}}
==GSC==
* {{medline-title
* {{medline-title
|title=[i]mastermind[/i] regulates niche ageing independently of the [i]Notch[/i] pathway in the [i]Drosophila[/i] ovary.
|title=Targeted, Amplicon-Based, Next-Generation Sequencing to Detect Age-Related Clonal Hematopoiesis.
|date=29.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31744422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893403
}}
* {{medline-title
|title=Germline stem cell homeostasis.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31155359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30941718
|full-text-url=https://sci-hub.do/10.1016/bs.ctdb.2019.04.006
|full-text-url=https://sci-hub.do/10.1007/7651_2019_216
}}
}}
* {{medline-title
* {{medline-title
|title=Endocrine regulation of female germline stem cells in the fruit fly Drosophila melanogaster.
|title=Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development.
|date=02.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109668
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30417440
|full-text-url=https://sci-hub.do/10.1016/j.cois.2018.07.001
|full-text-url=https://sci-hub.do/10.1002/jcp.27752
}}
}}
* {{medline-title
* {{medline-title
|title=Generation of Inducible Gene-Switched GAL4 Expressed in the [i]Drosophila[/i] Female Germline Stem Cell Niche.
|title=Concise Review: Age-Related Clonal Hematopoiesis: Stem Cells Tempting the Devil.
|date=05.06.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31018943
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553524
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125185
}}
}}
* {{medline-title
* {{medline-title
|title=YAP/Yorkie in the germline modulates the age-related decline of germline stem cells and niche cells.
|title=Effects of Parental Aging During Embryo Development and Adult Life: The Case of Nothobranchius furzeri.
|date=2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30943201
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304310
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447158
|full-text-url=https://sci-hub.do/10.1089/zeb.2017.1494
}}
}}
* {{medline-title
* {{medline-title
|title=Diminished Jak/STAT Signaling Causes Early-Onset Aging Defects in Stem Cell Cytokinesis.
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=21.01.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30612906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
}}
* {{medline-title
* {{medline-title
|title=JNK signaling triggers spermatogonial dedifferentiation during chronic stress to maintain the germline stem cell pool in the [i]Drosophila[/i] testis.
|title=An inflammatory environment containing TNFα favors Tet2-mutant clonal hematopoiesis.
|date=09.07.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29985130
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070334
|full-text-url=https://sci-hub.do/10.1016/j.exphem.2017.11.002
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related differences in BOLD modulation to cognitive control costs in a multitasking paradigm: Global switch, local switch, and compatibility-switch costs.
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|date=15.05.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29414492
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|full-text-url=https://sci-hub.do/10.1016/j.neuroimage.2018.01.030
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
}}
}}
* {{medline-title
* {{medline-title
|title=Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture.
|title=How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?
|date=22.02.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196443
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28792951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894940
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549890
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of [i]foxo[/i] rescues stem cell aging in [i]Drosophila[/i] germ line.
|title=miR-194 functions as a novel modulator of cellular senescence in mouse embryonic fibroblasts.
|date=19.09.2017
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28925355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27981676
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644957
|full-text-url=https://sci-hub.do/10.1002/cbin.10715
}}
}}
==IRS1==
* {{medline-title
* {{medline-title
|title=MicroRNA-34a causes ceramide accumulation and effects insulin signaling pathway by targeting ceramide kinase (CERK) in aging skeletal muscle.
|title=A primer for epigenetics of hematological malignancies.
|date=06.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056304
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27725578
|full-text-url=https://sci-hub.do/10.1002/jcb.29312
|full-text-url=https://sci-hub.do/10.11406/rinketsu.57.1835
}}
}}
* {{medline-title
* {{medline-title
|title=Longevity in response to lowered insulin signaling requires glycine N-methyltransferase-dependent spermidine production.
|title=Methylation of [[LOXL1]] Promoter by [[DNMT3A]] in Aged Human Skin Fibroblasts.
|date=01.2020
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31721422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27396912
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974722
|full-text-url=https://sci-hub.do/10.1089/rej.2016.1832
}}
}}
* {{medline-title
* {{medline-title
|title=Serine Phosphorylation of [[IRS1]] Correlates with Aβ-Unrelated Memory Deficits and Elevation in Aβ Level Prior to the Onset of Memory Decline in AD.
|title=Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy.
|date=17.08.2019
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31426549
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27147278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723493
|full-text-url=https://sci-hub.do/10.1111/ejh.12771
}}
}}
* {{medline-title
* {{medline-title
|title=Involvement of insulin receptor substrates in cognitive impairment and Alzheimer's disease.
|title=No association of the variant rs11887120 in [[DNMT3A]] with cognitive decline in individuals with mild cognitive impairment.
|date=08.2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30964050
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27092400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524492
|full-text-url=https://sci-hub.do/10.2217/epi-2015-0014
}}
}}
* {{medline-title
* {{medline-title
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|title=[[DNMT3A]] moderates cognitive decline in subjects with mild cognitive impairment: replicated evidence from two mild cognitive impairment cohorts.
|date=06.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26111027
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
|full-text-url=https://sci-hub.do/10.2217/epi.15.22
}}
}}
==E2F1==
* {{medline-title
* {{medline-title
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice.
|title=Regulation of [[E2F1]] activity via PKA-mediated phosphorylations.
|date=21.01.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33110360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585165
}}
}}
* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Astragaloside IV ameliorates radiation-induced senescence via antioxidative mechanism.
|date=02.2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32412100
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://sci-hub.do/10.1111/jphp.13284
}}
}}
* {{medline-title
* {{medline-title
|title=Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 ([[IRS1]]) in mice.
|title=[[E2F1]] mediates the downregulation of [[POLD1]] in replicative senescence.
|date=20.05.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29779018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30895337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588650
}}
}}
* {{medline-title
* {{medline-title
|title=Small nucleoli are a cellular hallmark of longevity.
|title=Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing [[NRARP]].
|date=30.08.2017
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28853436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30274778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582349
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.09.045
}}
}}
* {{medline-title
* {{medline-title
|title=An alternative model for studying age-associated metabolic complications: Senescence-accelerated mouse prone 8.
|title=Downregulation of [[FOXP1]] correlates with tendon stem/progenitor cells aging.
|date=01.12.2017
|date=26.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28843510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30170733
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.023
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.136
}}
}}
==KLF4==
* {{medline-title
* {{medline-title
|title=Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1α Activation.
|title=Loss of circadian protein [[TIMELESS]] accelerates the progression of cellular senescence.
|date=25.06.2020
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32630449
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30100061
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357081
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.040
}}
}}
* {{medline-title
* {{medline-title
|title=Soluble klotho regulates the function of salivary glands by activating [[KLF4]] pathways.
|title=Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence.
|date=02.10.2019
|date=30.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31581134
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814581
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935093
}}
}}
* {{medline-title
* {{medline-title
|title=Centenarians Overexpress Pluripotency-Related Genes.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=16.08.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
* {{medline-title
* {{medline-title
|title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis.
|title=Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation
|date=12.2018
|date=27.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660
}}
}}
* {{medline-title
* {{medline-title
|title=miR-10a rejuvenates aged human mesenchymal stem cells and improves heart function after myocardial infarction through [[KLF4]].
|title=Senescence-associated microRNAs target cell cycle regulatory genes in normal human lung fibroblasts.
|date=30.05.2018
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29848383
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28658612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977543
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.06.017
}}
}}
* {{medline-title
* {{medline-title
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|title=Neuronal tetraploidization in the cerebral cortex correlates with reduced cognition in mice and precedes and recapitulates Alzheimer's-associated neuropathology.
|date=10.04.2018
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28494436
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.04.008
}}
}}
* {{medline-title
* {{medline-title
|title=Kruppel-like factor 4 regulates keratinocyte senescence.
|title=Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle.
|date=05.05.2018
|date=30.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580988
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27840164
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139832
}}
}}
* {{medline-title
* {{medline-title
|title=Role of CD133 Molecule in Wnt Response and Renal Repair.
|title=Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression.
|date=03.2018
|date=21.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29431914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27818180
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519326
}}
}}
* {{medline-title
* {{medline-title
|title=Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.
|title=The activation of [[OR51E1]] causes growth suppression of human prostate cancer cells.
|date=15.10.2017
|date=26.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29138277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27374083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217014
}}
}}
* {{medline-title
* {{medline-title
|title=[[ZSCAN10]] expression corrects the genomic instability of iPSCs from aged donors.
|title=Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses.
|date=09.2017
|date=07.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26873092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843481
|full-text-url=https://sci-hub.do/10.1093/eurheartj/ehw001
}}
}}
==MPI==
* {{medline-title
* {{medline-title
|title=Age-related decline of lymphatic drainage from the eye: A noninvasive in vivo photoacoustic tomography study.
|title=[[CBX8]] antagonizes the effect of Sirtinol on premature senescence through the AKT-RB-[[E2F1]] pathway in K562 leukemia cells.
|date=05.2020
|date=22.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32251650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26718407
|full-text-url=https://sci-hub.do/10.1016/j.exer.2020.108029
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.12.070
}}
}}
* {{medline-title
* {{medline-title
|title=Interest of the multidimensional prognostic index ([[MPI]]) as an assessment tool in hospitalized patients in geriatrics.
|title=Nucleolar repression facilitates initiation and maintenance of senescence.
|date=01.12.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570330
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26505814
|full-text-url=https://sci-hub.do/10.1684/pnv.2019.0823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825723
}}
}}
* {{medline-title
* {{medline-title
|title=Reducing Potentially Inappropriate Medications in Older Adults: A Way Forward.
|title=Targeted gene mutation of [[E2F1]] evokes age-dependent synaptic disruption and behavioral deficits.
|date=12.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24460902
|full-text-url=https://sci-hub.do/10.1017/S0714980819000084
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028376
}}
}}
==EPO==
* {{medline-title
* {{medline-title
|title=The prognostic significance of geriatric syndromes and resources.
|title=Regulation of muscle and metabolic physiology by hypothalamic erythropoietin independently of its peripheral action.
|date=01.2020
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911909
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32029230
|full-text-url=https://sci-hub.do/10.1007/s40520-019-01168-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938905
}}
* {{medline-title
|title=Red Blood Cell Lifespan Shortening in Patients with Early-Stage Chronic Kidney Disease.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31550724
|full-text-url=https://sci-hub.do/10.1159/000502525
}}
}}
* {{medline-title
* {{medline-title
|title=[Polypharmacy and associated factors in elderly diabetic].
|title=Age-Dependent Systemic Effects of a Systemic Intermittent Hypoxic Therapy [i]In Vivo[/i].
|date=05-06.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30844011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260338
|full-text-url=https://sci-hub.do/10.15446/rsap.V20n3.50304
|full-text-url=https://sci-hub.do/10.1089/ham.2018.0113
}}
}}
* {{medline-title
* {{medline-title
|title=An examination of the concordance between self-reported collisions, driver records, and insurance claims in older drivers.
|title=Erythropoietin does not improve fracture healing in aged mice.
|date=12.2018
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30553426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30998964
|full-text-url=https://sci-hub.do/10.1016/j.jsr.2018.07.007
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.04.005
}}
}}
* {{medline-title
* {{medline-title
|title=Age Modifies the Association of Dietary Protein Intake with All-Cause Mortality in Patients with Chronic Kidney Disease.
|title=Dose-response relationship of intermittent normobaric hypoxia to stimulate erythropoietin in the context of health promotion in young and old people.
|date=13.11.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30428524
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30756167
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265861
|full-text-url=https://sci-hub.do/10.1007/s00421-019-04096-8
}}
}}
* {{medline-title
* {{medline-title
|title=New associations of the Multidimensional Prognostic Index.
|title=rh[[EPO]] Enhances Cellular Anti-oxidant Capacity to Protect Long-Term Cultured Aging Primary Nerve Cells.
|date=08.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30406302
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28634693
|full-text-url=https://sci-hub.do/10.1007/s00391-018-01471-6
|full-text-url=https://sci-hub.do/10.1007/s12031-017-0937-6
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of oral amino acid supplementation on Multidimensional Prognostic Index in hospitalized older patients: a multicenter randomized, double-blind, placebo-controlled pilot study.
|title=[Effects of recombinant human erythropoietin on brain-derived neurotrophic factor expression in different brain regions of aging rats].
|date=2018
|date=20.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28446413
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908340
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744085
}}
}}
* {{medline-title
* {{medline-title
|title=Degree of Peripheral Thyroxin Deiodination, Frailty, and Long-Term Survival in Hospitalized Older Patients.
|title=Warming Up to New Possibilities with the Capsaicin Receptor [[TRPV1]]: mTOR, AMPK, and Erythropoietin.
|date=01.05.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546287
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28294062
|full-text-url=https://sci-hub.do/10.1210/jc.2017-02149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478459
}}
}}
==NAMPT==
* {{medline-title
* {{medline-title
|title=Over-expression of Nicotinamide phosphoribosyltransferase in mouse cells confers protective effect against oxidative and ER stress-induced premature senescence.
|title=The Anti-Aging Effect of Erythropoietin via the ERK/Nrf2-ARE Pathway in Aging Rats.
|date=08.2020
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32533606
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28168414
|full-text-url=https://sci-hub.do/10.1111/gtc.12794
|full-text-url=https://sci-hub.do/10.1007/s12031-017-0885-1
}}
}}
* {{medline-title
* {{medline-title
|title=Resistance training increases muscle NAD  and NADH concentrations as well as [[NAMPT]] protein levels and global sirtuin activity in middle-aged, overweight, untrained individuals.
|title=Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations.
|date=05.05.2020
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32369778
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27959434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288928
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355685
}}
}}
* {{medline-title
* {{medline-title
|title=Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase ([[NAMPT]]) and Sirtuin-1 (SIRT-1) Pathway in Obesity and T2DM: Modulation by Metformin and Macronutrient Intake.
|title=Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life Expectancy.
|date=2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920356
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27488211
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938199
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079807
}}
}}
* {{medline-title
* {{medline-title
|title=Aerobic and resistance exercise training reverses age-dependent decline in NAD  salvage capacity in human skeletal muscle.
|title=Erythropoietin Does Not Enhance Skeletal Muscle Protein Synthesis Following Exercise in Young and Older Adults.
|date=07.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31207144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27458387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6577427
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937030
}}
}}
* {{medline-title
* {{medline-title
|title=Extracellular Vesicle-Contained e[[NAMPT]] Delays Aging and Extends Lifespan in Mice.
|title=Oxidative stress induces the decline of brain [[EPO]] expression in aging rats.
|date=06.08.2019
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31204283
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27452792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687560
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.07.012
}}
}}
* {{medline-title
* {{medline-title
|title=lncRNA GAS5/miR-223/[[NAMPT]] axis modulates the cell proliferation and senescence of endothelial progenitor cells through PI3K/AKT signaling.
|title=Sub-acute systemic erythropoietin administration reduces ischemic brain injury in an age-dependent manner.
|date=09.2019
|date=14.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27248662
|full-text-url=https://sci-hub.do/10.1002/jcb.28713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094944
}}
}}
* {{medline-title
* {{medline-title
|title=Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training.
|title=Erythropoietin Attenuates the Memory Deficits in Aging Rats by Rescuing the Oxidative Stress and Inflammation and Promoting [[BDNF]] Releasing.
|date=2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283350
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26482461
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156423
|full-text-url=https://sci-hub.do/10.1007/s12035-015-9438-1
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of [[NAMPT]] in aging retinal pigment epithelium reduces NAD  availability and promotes cellular senescence.
|title=rh[[EPO]] affects apoptosis in hippocampus of aging rats by upregulating [[SIRT1]].
|date=12.06.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905535
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26261574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046249
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525908
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating [[SIRT1]] activity and antioxidant gene expression in mouse cells.
|title=Coated dextrin microcapsules of amlodipine incorporable into orally disintegrating tablets for geriatric patients.
|date=12.2017
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29178516
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25458788
|full-text-url=https://sci-hub.do/10.1111/gtc.12542
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2014.10.010
}}
}}
* {{medline-title
* {{medline-title
|title=Deletion of Nampt in Projection Neurons of Adult Mice Leads to Motor Dysfunction, Neurodegeneration, and Death.
|title=Neocytolysis: none, one or many? A reappraisal and future perspectives.
|date=29.08.2017
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854367
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24592241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021762
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924315
}}
}}
==PSD==
==GAL==


* {{medline-title
* {{medline-title
|title=Quantitative Immunoblotting Analyses Reveal that the Abundance of Actin, Tubulin, Synaptophysin and EEA1 Proteins is Altered in the Brains of Aged Mice.
|title=Overexpression of Pitx1 attenuates the senescence of chondrocytes from osteoarthritis degeneration cartilage-A self-controlled model for studying the etiology and treatment of osteoarthritis.
|date=21.08.2020
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32652177
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783149
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2020.06.044
|full-text-url=https://sci-hub.do/10.1016/j.bone.2019.115177
}}
}}
* {{medline-title
* {{medline-title
|title=Exercise Attenuates Brain Aging by Rescuing Down-Regulated Wnt/β-Catenin Signaling in Aged Rats.
|title=β-Caryophyllene Reduces DNA Oxidation and the Overexpression of Glial Fibrillary Acidic Protein in the Prefrontal Cortex and Hippocampus of d-Galactose-Induced Aged BALB/c Mice.
|date=2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32390823
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31663807
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192222
|full-text-url=https://sci-hub.do/10.1089/jmf.2019.0111
}}
}}
* {{medline-title
* {{medline-title
|title=Concurrent nicotine exposure to prenatal alcohol consumption alters the hippocampal and cortical neurotoxicity.
|title=Senescence-associated β-galactosidase activity in the developing avian retina.
|date=01.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31938742
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31226225
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953639
|full-text-url=https://sci-hub.do/10.1002/dvdy.74
}}
}}
* {{medline-title
* {{medline-title
|title=The Experience of Family Physicians and Home Health Staff Involved in an Intervention to Increase Patient-Related Collaboration.
|title=Zeaxanthin Isolated from [i]Dunaliella salina[/i] Microalgae Ameliorates Age Associated Cardiac Dysfunction in Rats through Stimulation of Retinoid Receptors.
|date=12.2019
|date=14.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31094303
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31091726
|full-text-url=https://sci-hub.do/10.1017/S071498081900014X
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562725
}}
}}
* {{medline-title
* {{medline-title
|title=Pterostilbene Improves Cognitive Performance in Aged Rats: An in Vivo Study.
|title=Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway.
|date=2019
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30816671
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039346
|full-text-url=https://sci-hub.do/10.33594/000000017
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2019.04.043
}}
}}
* {{medline-title
* {{medline-title
|title=Higher Levels of Protein Palmitoylation in the Frontal Cortex across Aging Were Associated with Reference Memory and Executive Function Declines.
|title=[[MYC]] and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts.
|date=01-02.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30740518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526305
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343716
}}
}}
* {{medline-title
* {{medline-title
|title=A single cocaine administration alters dendritic spine morphology and impairs glutamate receptor synaptic retention in the medial prefrontal cortex of adolescent rats.
|title=Manipulation of molecular pathways and senescence hallmarks by natural compounds in fibroblast cells.
|date=15.09.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30474871
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2018.08.006
|full-text-url=https://sci-hub.do/10.1002/jcb.27909
}}
}}
* {{medline-title
* {{medline-title
|title=Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning.
|title=Ellagic acid reveals promising anti-aging effects against d-galactose-induced aging on human neuroblastoma cell line, SH-SY5Y: A mechanistic study.
|date=02.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29793890
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30372874
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2018.05.007
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.10.024
}}
}}
* {{medline-title
* {{medline-title
|title=Dynamic SAP102 expression in the hippocampal subregions of rats and APP/PS1 mice of various ages.
|title=Molecular and biochemical evidence on the protective role of ellagic acid and silybin against oxidative stress-induced cellular aging.
|date=06.2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29574717
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28887692
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979819
|full-text-url=https://sci-hub.do/10.1007/s11010-017-3172-0
}}
}}
* {{medline-title
* {{medline-title
|title=Downregulated Nuclear Factor E2-Related Factor 2 (Nrf2) Aggravates Cognitive Impairments via Neuroinflammation and Synaptic Plasticity in the Senescence-Accelerated Mouse Prone 8 (SAMP8) Mouse: A Model of Accelerated Senescence.
|title=Hyperphosphatemia induces senescence in human endothelial cells by increasing endothelin-1 production.
|date=23.02.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29474348
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28857396
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833362
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676064
}}
}}
==REST==
* {{medline-title
* {{medline-title
|title=[Brain and Neuronal Aging: Aged Brain Controls via Gene Expression Fidelity and Master Regulatory Factors].
|title=Carnosine Treatment Diminished Oxidative Stress and Glycation Products in Serum and Tissues of D-Galactose-Treated Rats.
|date=2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676006
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00193-4
|full-text-url=https://sci-hub.do/10.2174/1871530317666170703123519
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of 9 - PAHSA on cognitive dysfunction in diabetic mice and its possible mechanism.
|title=Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study.
|date=09.04.2020
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32014256
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26573928
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.01.071
|full-text-url=https://sci-hub.do/10.1007/s12022-015-9405-4
}}
}}
* {{medline-title
* {{medline-title
|title=Increased [[REST]] to Optimize Life Span?
|title=Carnosine and taurine treatments diminished brain oxidative stress and apoptosis in D-galactose aging model.
|date=12.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31762373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26518192
|full-text-url=https://sci-hub.do/10.1089/rej.2019.2287
|full-text-url=https://sci-hub.do/10.1007/s11011-015-9755-0
}}
}}
* {{medline-title
* {{medline-title
|title=Cardiac baroreflex hysteresis is one of the determinants of the heart period variability asymmetry.
|title=The role of T[[ORC1]] in muscle development in Drosophila.
|date=01.10.2019
|date=13.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31365303
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25866192
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00112.2019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394354
}}
}}
* {{medline-title
* {{medline-title
|title=Pterostilbene Improves Cognitive Performance in Aged Rats: An in Vivo Study.
|title=N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models.
|date=2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30816671
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25860694
|full-text-url=https://sci-hub.do/10.33594/000000017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393098
}}
}}
* {{medline-title
* {{medline-title
|title=Comparison between probabilistic and Wiener-Granger causality in assessing modifications of the cardiac baroreflex control with age.
|title=Five years of interdisciplinary research on ageing and technology: Outcomes of the Lower Saxony Research Network Design of Environments for Ageing ([[GAL]])--an introduction to this Special Issue on Ageing and Technology.
|date=22.10.2018
|date=09-12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30207986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25148555
|full-text-url=https://sci-hub.do/10.1088/1361-6579/aae0ec
|full-text-url=https://sci-hub.do/10.3109/17538157.2014.931854
}}
}}
* {{medline-title
* {{medline-title
|title=Fast-Evolving Human-Specific Neural Enhancers Are Associated with Aging-Related Diseases.
|title=Information and communication technologies for promoting and sustaining quality of life, health and self-sufficiency in ageing societies--outcomes of the Lower Saxony Research Network Design of Environments for Ageing ([[GAL]]).
|date=23.05.2018
|date=09-12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29792826
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25148556
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972385
|full-text-url=https://sci-hub.do/10.3109/17538157.2014.931849
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of age and gender on the phase and strength of the relation between heart period and systolic blood pressure spontaneous fluctuations.
|title=Cyanidin-3-O-galactoside and blueberry extracts supplementation improves spatial memory and regulates hippocampal ERK expression in senescence-accelerated mice.
|date=01.03.2018
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29212671
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24709099
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00903.2017
|full-text-url=https://sci-hub.do/10.3967/bes2014.007
}}
}}
==NQO1==
* {{medline-title
* {{medline-title
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|title=Augmentation of cellular NAD  by [[NQO1]] enzymatic action improves age-related hearing impairment.
|date=2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31353811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718544
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA Expression Analysis of Centenarians and Rheumatoid Arthritis Patients Reveals a Common Expression Pattern.
|title=Well-aging: A new strategy for skin homeostasis under multi-stressed conditions.
|date=2017
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28824293
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31232507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562112
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003805
}}
}}
==SIRT2==
* {{medline-title
* {{medline-title
|title=Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the [[SIRT2]]-dependent H4K16 deacetylation pathway.
|title=Limitations to adaptive homeostasis in an hyperoxia-induced model of accelerated ageing.
|date=24.01.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31980591
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31022673
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053624
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479762
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT2]] functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.
|title=Link between cardiac function and the antioxidative defense mechanism in aged rats.
|date=01.09.2019
|date=11.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31295472
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31010674
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116639
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.03.182
}}
}}
* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats].
|date=2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180408.005
}}
}}
* {{medline-title
* {{medline-title
|title=Mitochondrial Stress-Initiated Aberrant Activation of the [[NLRP3]] Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging.
|title=Benefits of Caloric Restriction in Longevity and Chemical-Induced Tumorigenesis Are Transmitted Independent of [[NQO1]].
|date=22.01.2019
|date=16.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673616
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733330
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599277
}}
}}
* {{medline-title
* {{medline-title
|title=Hsp90 Stabilizes [[SIRT1]] Orthologs in Mammalian Cells and [i]C. elegans[/i].
|title=Overexpression of [[CYB5R3]] and [[NQO1]], two NAD  -producing enzymes, mimics aspects of caloric restriction.
|date=20.11.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463299
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052403
}}
}}
* {{medline-title
* {{medline-title
|title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes.
|title=Sargassum fusiforme Polysaccharide Rejuvenat es the Small Intestine in Mice Through Altering its Physiol ogy and Gut Microbiota Composition.
|date=01.05.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29210649
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186
|full-text-url=https://sci-hub.do/10.2174/1566524018666171205115516
}}
}}
* {{medline-title
* {{medline-title
|title=High expression of CPT1b in skeletal muscle in metabolically healthy older subjects.
|title=Apigenin exhibits protective effects in a mouse model of d-galactose-induced aging via activating the Nrf2 pathway.
|date=04.2019
|date=21.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657112
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28598487
|full-text-url=https://sci-hub.do/10.1016/j.diabet.2018.01.018
|full-text-url=https://sci-hub.do/10.1039/c7fo00037e
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans.
|title=The ontogeny and population variability of human hepatic dihydronicotinamide riboside:quinone oxidoreductase ([[NQO2]]).
|date=2017
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28346733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715387
|full-text-url=https://sci-hub.do/10.1002/jbt.21921
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of [[SIRT2]] leads to axonal degeneration and locomotor disability associated with redox and energy imbalance.
|title=Gardenia jasminoides extract-capped gold nanoparticles reverse hydrogen peroxide-induced premature senescence.
|date=12.2017
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28984064
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27693841
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676070
|full-text-url=https://sci-hub.do/10.1016/j.jphotobiol.2016.09.033
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT2]] Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy.
|title=Stimulation of cellular senescent processes, including secretory phenotypes and anti-oxidant responses, after androgen deprivation therapy in human prostate cancer.
|date=21.11.2017
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28947430
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329245
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698109
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2016.06.007
}}
}}
==TLR2==
* {{medline-title
* {{medline-title
|title=Changes in salivary microbial sensing proteins CD14 and [[TLR2]] with aging.
|title=Exercise-induced Nrf2-signaling is impaired in aging.
|date=07.2020
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32529494
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27109910
|full-text-url=https://sci-hub.do/10.1007/s00784-020-03274-9
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.04.024
}}
}}
* {{medline-title
* {{medline-title
|title=Culture Model for Non-human Primate Choroid Plexus.
|title=Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress.
|date=2019
|date=05.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31555096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27048381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724611
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822244
}}
* {{medline-title
|title=The Ontogeny and Population Variability of Human Hepatic NADPH Dehydrogenase Quinone Oxido-Reductase 1 ([[NQO1]]).
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26856346
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931887
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in fetal membrane histology with cervical insufficiency and transabdominal cerclage.
|title=Acetaminophen hepatotoxicity in mice: Effect of age, frailty and exposure type.
|date=08.2019
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31004354
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26615879
|full-text-url=https://sci-hub.do/10.1002/ijgo.12826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976491
}}
}}
* {{medline-title
* {{medline-title
|title=Aging leads to dysfunctional innate immune responses to [[TLR2]] and [[TLR4]] agonists.
|title=[[NQO1]] Stabilizes p53 in Response to Oncogene-Induced Senescence.
|date=09.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30402800
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26078718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504629
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466457
}}
}}
* {{medline-title
* {{medline-title
|title=The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease.
|title=Neophobia, [[NQO1]] and [[SIRT1]] as premorbid and prodromal indicators of AD in 3xTg-AD mice.
|date=10.2018
|date=01.09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30271656
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24837743
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147589
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2014.04.055
}}
}}
==TREM2==
* {{medline-title
* {{medline-title
|title=Aging modulates microglia phenotypes in neuroinflammation of MPTP-PD mice.
|title=Loss of [[TREM2]] Confers Resilience to Synaptic and Cognitive Impairment in Aged Mice.
|date=01.10.2018
|date=09.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30009921
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33139402
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.010
|full-text-url=https://sci-hub.do/10.1523/JNEUROSCI.2193-20.2020
}}
}}
* {{medline-title
* {{medline-title
|title=Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice.
|title=Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer's Disease Brain.
|date=24.08.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29929978
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33101276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546799
}}
}}
* {{medline-title
* {{medline-title
|title=Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging.
|title=Knockdown of astrocytic [[TREM2]] in the hippocampus relieves cognitive decline in elderly male mice.
|date=05.2018
|date=15.01.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32991925
|full-text-url=https://sci-hub.do/10.1002/cyto.a.23372
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2020.112939
}}
}}
* {{medline-title
* {{medline-title
|title=[[TLR4]] and [[TLR2]] activation is differentially associated with age during Parkinson's disease.
|title=Immune Signaling in Neurodegeneration.
|date=01.2018
|date=16.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29077524
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30995509
|full-text-url=https://sci-hub.do/10.1080/08820139.2017.1379024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822103
}}
}}
* {{medline-title
* {{medline-title
|title=Role of pattern recognition receptors of the neurovascular unit in inflamm-aging.
|title=The Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) as Expression of the Relationship between Microglia and Alzheimer's Disease: A Novel Marker for a Promising Pathway to Explore.
|date=01.11.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28801521
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30997915
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00106.2017
|full-text-url=https://sci-hub.do/10.14283/jfa.2018.43
}}
}}
==UCP1==
* {{medline-title
* {{medline-title
|title=Muscle-dependent regulation of adipose tissue function in long-lived growth hormone-mutant mice.
|title=[[TREM2]] triggers microglial density and age-related neuronal loss.
|date=28.05.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32464603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266
}}
}}
* {{medline-title
* {{medline-title
|title=Lack of [[UCP1]] stimulates fatty liver but mediates [[UCP1]]-independent action of beige fat to improve hyperlipidemia in Apoe knockout mice.
|title=Differential effects of partial and complete loss of [[TREM2]] on microglial injury response and tauopathy.
|date=01.07.2020
|date=02.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32179129
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30232263
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165762
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176614
}}
}}
* {{medline-title
* {{medline-title
|title=Postnatal leptin surge is critical for the transient induction of the developmental beige adipocytes in mice.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=01.04.2020
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31961706
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191411
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice.
|title=Differential Phagocytic Properties of CD45  Microglia and CD45  Brain Mononuclear Phagocytes-Activation and Age-Related Effects.
|date=05.12.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31806023
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29552013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896328
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840283
}}
}}
* {{medline-title
* {{medline-title
|title=An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise.
|title=Microglia and Aging: The Role of the [[TREM2]]-DAP12 and [[CX3CL1]]-[[CX3CR1]] Axes.
|date=19.08.2019
|date=22.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31427677
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29361745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796261
}}
}}
* {{medline-title
* {{medline-title
|title=Brown and Beige Adipose Tissue and Aging.
|title=A Tale of Two Genes: Microglial Apoe and Trem2.
|date=2019
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31281288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28930654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595248
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2017.08.015
}}
* {{medline-title
|title=[[TREM2]], Microglia, and Neurodegenerative Diseases.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28442216
|full-text-url=https://sci-hub.do/10.1016/j.molmed.2017.03.008
}}
* {{medline-title
|title=Neuroprotective Effect of TREM-2 in Aging and Alzheimer's Disease Model.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27662313
|full-text-url=https://sci-hub.do/10.3233/JAD-160663
}}
* {{medline-title
|title=Cerebrospinal fluid soluble [[TREM2]] in aging and Alzheimer's disease.
|date=27.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27121148
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848774
}}
* {{medline-title
|title=Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease.
|date=18.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26888450
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757836
}}
* {{medline-title
|title=Dark microglia: A new phenotype predominantly associated with pathological states.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26847266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949554
}}
* {{medline-title
|title=[[TREM2]] Overexpression has No Improvement on Neuropathology and Cognitive Impairment in Aging APPswe/PS1dE9 Mice.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26780455
|full-text-url=https://sci-hub.do/10.1007/s12035-016-9704-x
}}
* {{medline-title
|title=[[TREM2]] sustains microglial expansion during aging and response to demyelination.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25893602
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463196
}}
==TSPO==
 
* {{medline-title
|title=Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31749696
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848890
}}
* {{medline-title
|title=Upregulation of cannabinoid receptor type 2, but not [[TSPO]], in senescence-accelerated neuroinflammation in mice: a positron emission tomography study.
|date=10.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31707986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842455
}}
* {{medline-title
|title=Effects of age, BMI and sex on the glial cell marker [[[[TSPO]]]] - a multicentre [ C]PBR28 HRRT PET study.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31363804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717599
}}
* {{medline-title
|title=Concentration, distribution, and influence of aging on the 18 kDa translocator protein in human brain: Implications for brain imaging studies.
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220997
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181090
}}
* {{medline-title
|title=Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study.
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400912
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220478
}}
}}
* {{medline-title
* {{medline-title
|title=Resveratrol and HIV-protease inhibitors control [[UCP1]] expression through opposite effects on p38 MAPK phosphorylation in human adipocytes.
|title=Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
|date=02.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31294462
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297998
|full-text-url=https://sci-hub.do/10.1002/jcp.29032
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating factors present in the sera of naturally skinny people may influence cell commitment and adipocyte differentiation of mesenchymal stromal cells.
|title=[[[[TSPO]]]] ligand PK11195 improves Alzheimer-related outcomes in aged female 3xTg-AD mice.
|date=26.03.2019
|date=14.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30949296
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29925037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436542
}}
}}
* {{medline-title
* {{medline-title
|title=Assessment of the Aging of the Brown Adipose Tissue by  F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna .
|title=Imaging studies of the HIV-infected brain.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604980
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079616
|full-text-url=https://sci-hub.do/10.1016/B978-0-444-63849-6.00018-9
}}
}}
* {{medline-title
* {{medline-title
|title=Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice.
|title=Steroidogenic abnormalities in translocator protein knockout mice and significance in the aging male.
|date=08.2018
|date=02.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29903737
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29127254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092113
|full-text-url=https://sci-hub.do/10.1042/BCJ20170645
}}
}}
* {{medline-title
|title=Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28705919
|full-text-url=https://sci-hub.do/10.2967/jnumed.117.195107
}}
* {{medline-title
|title=Depiction of microglial activation in aging and dementia: Positron emission tomography with [ C]DPA713 versus [ C]( R)PK11195.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27117856
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363467
}}
* {{medline-title
|title=In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by 18F-GE180 [[[[TSPO]]]] MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice.
|date=25.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26609163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705465
}}
* {{medline-title
|title=[[[[TSPO]]]] in a murine model of Sandhoff disease: presymptomatic marker of neurodegeneration and disease pathophysiology.
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26545928
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688219
}}
* {{medline-title
|title=Translocator protein: pharmacology and steroidogenesis.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26551695
|full-text-url=https://sci-hub.do/10.1042/BST20150061
}}
* {{medline-title
|title=Translocator protein ([[TSPO]]) role in aging and Alzheimer's disease.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25495567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435228
}}
* {{medline-title
|title=Evaluation of basal ganglia and thalamic inflammation in children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection and tourette syndrome: a positron emission tomographic (PET) study using 11C-[R]-PK11195.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25117419
|full-text-url=https://sci-hub.do/10.1177/0883073814543303
}}
* {{medline-title
|title=Genetic analysis of d[[[[TSPO]]]], an outer mitochondrial membrane protein, reveals its functions in apoptosis, longevity, and Ab42-induced neurodegeneration.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24977274
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076708
}}
* {{medline-title
|title=Comparing amyloid-β deposition, neuroinflammation, glucose metabolism, and mitochondrial complex I activity in brain: a PET study in aged monkeys.
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24919653
|full-text-url=https://sci-hub.do/10.1007/s00259-014-2821-8
}}
==UCP2==
* {{medline-title
|title=Potential Role of Leptin in Cardiac Steatosis Induced by Highly Saturated Fat Intake during Adolescence.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298470
|full-text-url=https://sci-hub.do/10.1002/mnfr.201900110
}}
* {{medline-title
|title=Effect of Initial Aging and High-Fat/High-Fructose Diet on Mitochondrial Bioenergetics and Oxidative Status in Rat Brain.
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089964
|full-text-url=https://sci-hub.do/10.1007/s12035-019-1617-z
}}
* {{medline-title
|title=Decreased uncoupling protein 2 expression in aging retinal pigment epithelial cells.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30918803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423381
}}
* {{medline-title
|title=The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature.
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30676214
|full-text-url=https://sci-hub.do/10.1123/japa.2018-0155
}}
* {{medline-title
|title=G-1 exhibit antidepressant effect, increase of hippocampal ERs expression and improve hippocampal redox status in aged female rats.
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30041006
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2018.07.017
}}
* {{medline-title
|title=Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts.
|date=21.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29931650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060207
}}
* {{medline-title
|title=Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/[[PGC]]-1α pathway.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325933
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820139
}}
* {{medline-title
|title=Pleiotropic effects of [[UCP2]]-[[UCP3]] variability on leucocyte telomere length and glucose homeostasis.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28281015
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9690-z
}}
* {{medline-title
|title=Thyroid hormone-stimulated increases in [[PGC]]-1α and [[UCP2]] promote life history-specific endocrine changes and maintain a lipid-based metabolism.
|date=01.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27903512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336568
}}
* {{medline-title
|title=Uncoupling protein 2 deficiency results in higher neutrophil counts and lower B-cell counts during aging in mice.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27544660
|full-text-url=https://sci-hub.do/10.1016/j.exphem.2016.08.003
}}
* {{medline-title
|title=Voluntary Running Aids to Maintain High Body Temperature in Rats Bred for High Aerobic Capacity.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27504097
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958631
}}
* {{medline-title
|title=Uncoupling protein 2 protects mice from aging.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27364833
|full-text-url=https://sci-hub.do/10.1016/j.mito.2016.06.004
}}
* {{medline-title
|title=Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes [[UCP2]] and [[UCP3]] affect mitochondrial metabolism and healthy aging in female nonagenarians.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26965008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935613
}}
* {{medline-title
|title=Differential modulation of AMPK/PPARα/[[UCP2]] axis in relation to hypertension and aging in the brain, kidneys and heart of two closely related spontaneously hypertensive rat strains.
|date=07.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26023797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662457
}}
* {{medline-title
|title=[Genotype and allele frequencies of U[[CP]] and PP[[AR]] gene families in residents of besieged Leningrad and in the control group].
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826986
}}
* {{medline-title
|title=Activation of PPAR-γ by pioglitazone attenuates oxidative stress in aging rat cerebral arteries through upregulating [[UCP2]].
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25490415
|full-text-url=https://sci-hub.do/10.1097/FJC.0000000000000143
}}
* {{medline-title
|title=Loss of [[UCP2]] attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24945157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063685
}}
* {{medline-title
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201
}}
==CXCL10==
* {{medline-title
|title=Age-related decline of interferon-gamma responses in macrophage impairs satellite cell proliferation and regeneration.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32725722
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567146
}}
* {{medline-title
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004
}}
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
* {{medline-title
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
}}
* {{medline-title
|title=Aged Chinese-origin rhesus macaques infected with SIV develop marked viremia in absence of clinical disease, inflammation or cognitive impairment.
|date=01.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29391069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796498
}}
* {{medline-title
|title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006
}}
* {{medline-title
|title=Dysregulation of C-X-C motif ligand 10 during aging and association with cognitive performance.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29223680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805841
}}
* {{medline-title
|title=Selected life-extending interventions reduce arterial [[CXCL10]] and macrophage colony-stimulating factor in aged mouse arteries.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28390264
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544385
}}
* {{medline-title
|title=Interferon-gamma deficiency protects against aging-related goblet cell loss.
|date=04.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27623073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323102
}}
* {{medline-title
|title=Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27094468
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.014
}}
* {{medline-title
|title=In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27081760
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906944
}}
* {{medline-title
|title=Thinning of the [[RPE]] and choroid associated with T lymphocyte recruitment in aged and light-challenged mice.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26392743
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558476
}}
* {{medline-title
|title=[[CCL2]], [[CXCL8]], [[CXCL9]] and [[CXCL10]] serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25955863
|full-text-url=https://sci-hub.do/10.1111/1756-185X.12589
}}
* {{medline-title
|title=Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834936
|full-text-url=https://sci-hub.do/10.1016/j.patbio.2015.03.002
}}
* {{medline-title
|title=Viremic and Virologically Suppressed HIV Infection Increases Age-Related Changes to Monocyte Activation Equivalent to 12 and 4 Years of Aging, Respectively.
|date=01.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25647525
|full-text-url=https://sci-hub.do/10.1097/QAI.0000000000000559
}}
* {{medline-title
|title=Increased recruitment of bone marrow-derived cells into the brain associated with altered brain cytokine profile in senescence-accelerated mice.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25577138
|full-text-url=https://sci-hub.do/10.1007/s00429-014-0987-2
}}
* {{medline-title
|title=Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state.
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24759206
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205198
}}
==FAS==
* {{medline-title
|title=Five-year change in maximum tongue pressure and physical function in community-dwelling elderly adults.
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32952883
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486543
}}
* {{medline-title
|title=Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32064756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059172
}}
* {{medline-title
|title=Application of GFR estimation equations in elderly patients with measured GFR below 60 mL/min/1.73 m .
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31115878
|full-text-url=https://sci-hub.do/10.1007/s40520-019-01218-2
}}
* {{medline-title
|title=Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677513
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2019.01.005
}}
* {{medline-title
|title=Genetic and Environmental Influences on Language Ability in Older Adults: Findings from the Older Australian Twins Study.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29619677
|full-text-url=https://sci-hub.do/10.1007/s10519-018-9897-z
}}
* {{medline-title
|title=Effects of aging on fat deposition and meat quality in Sheldrake duck.
|date=01.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29554357
|full-text-url=https://sci-hub.do/10.3382/ps/pey077
}}
* {{medline-title
|title=Impact of sociodemographic variables on executive functions.
|date=01-03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29213495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619216
}}
* {{medline-title
|title=Prevalence of Impaired Kidney Function in the German Elderly: Results from the Berlin Aging Study II (BASE-II).
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28231583
|full-text-url=https://sci-hub.do/10.1159/000454831
}}
* {{medline-title
|title=Multiple category verbal fluency in mild cognitive impairment and correlation with CSF biomarkers for Alzheimer's disease.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28179036
|full-text-url=https://sci-hub.do/10.1017/S1041610217000102
}}
* {{medline-title
|title=Glomerular Filtration Rate in Healthy Living Potential Kidney Donors: A Meta-Analysis Supporting the Construction of the Full Age Spectrum Equation.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27764827
|full-text-url=https://sci-hub.do/10.1159/000450893
}}
* {{medline-title
|title=Life Expectancy of People with Fetal Alcohol Syndrome.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26962962
}}
* {{medline-title
|title=Increased susceptibility of [[CD4]]  T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced [[CD4]] and enhanced [[CXCR4]] and [[FAS]] surface expression levels.
|date=09.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26452480
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600300
}}
* {{medline-title
|title=Systemic Akt1 Deletion after Tumor Onset in p53(-/-) Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration.
|date=28.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26190111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526157
}}
* {{medline-title
|title=Impact of loss of NF-κB1, NF-κB2 or c-[[REL]] on SLE-like autoimmune disease and lymphadenopathy in Fas(lpr/lpr) mutant mice.
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26084385
|full-text-url=https://sci-hub.do/10.1038/icb.2015.66
}}
* {{medline-title
|title=Longitudinal measures of perfluoroalkyl substances (P[[FAS]]) in serum of Gullah African Americans in South Carolina: 2003-2013.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25819541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583839
}}
* {{medline-title
|title=White Adipose Tissue Depot-Specific Activity of Lipogenic Enzymes in Response to Fasting and Refeeding in Young and Old Rats.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25721559
|full-text-url=https://sci-hub.do/10.1159/000371578
}}
* {{medline-title
|title=Short-term calorie restriction and refeeding differently affect lipogenic enzymes in major white adipose tissue depots of young and old rats.
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24622836
}}
==FH==
* {{medline-title
|title=Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33252089
|full-text-url=https://sci-hub.do/10.3233/JAD-201058
}}
* {{medline-title
|title=Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia.
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32311609
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.03.006
}}
* {{medline-title
|title=Macroscopic hematuria as a risk factor for hypertension in ageing people with hemophilia and a family history of hypertension.
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32118768
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478422
}}
* {{medline-title
|title=LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31815695
|full-text-url=https://sci-hub.do/10.3233/JAD-190742
}}
* {{medline-title
|title=Sex differences in cholesterol levels from birth to 19 years of age may lead to increased cholesterol burden in females with [[FH]].
|date=05-06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29609857
|full-text-url=https://sci-hub.do/10.1016/j.jacl.2018.02.021
}}
* {{medline-title
|title=Association between lipoprotein (a) and proprotein convertase substilisin/kexin type 9 in patients with heterozygous familial hypercholesterolemia: A case-control study.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129821
|full-text-url=https://sci-hub.do/10.1016/j.metabol.2017.11.004
}}
* {{medline-title
|title=Longitudinal Assessment of Self- and Informant-Subjective Cognitive Complaints in a Sample of Healthy Late-Middle Aged Adults Enriched with a Family History of Alzheimer's Disease.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28693655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754023
}}
* {{medline-title
|title=Diffusion Tensor Imaging Predictors of Episodic Memory Decline in Healthy Elders at Genetic Risk for Alzheimer's Disease.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27903333
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916766
}}
* {{medline-title
|title=Familial hypercholesterolaemia reduces the quality of life of patients not reaching treatment targets.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27127013
}}
* {{medline-title
|title=Effect of fetal hypothyroidism on tolerance to ischemia-reperfusion injury in aged male rats: Role of nitric oxide.
|date=01.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27074518
|full-text-url=https://sci-hub.do/10.1016/j.niox.2016.04.001
}}
* {{medline-title
|title=Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment.
|date=21.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26009596
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576143
}}
* {{medline-title
|title=Impact of family history of alcoholism on glutamine/glutamate ratio in anterior cingulate cortex in substance-naïve adolescents.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26025607
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618784
}}
* {{medline-title
|title=Age-Based Differences in the Genetic Determinants of Glycemic Control: A Case of [[FOXO3]] Variations.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25993007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439071
}}
* {{medline-title
|title=The Mechanism of Ligamentum Flavum Hypertrophy: Introducing Angiogenesis as a Critical Link That Couples Mechanical Stress and Hypertrophy.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25850600
|full-text-url=https://sci-hub.do/10.1227/NEU.0000000000000755
}}
* {{medline-title
|title=Longitudinal measures of perfluoroalkyl substances (P[[FAS]]) in serum of Gullah African Americans in South Carolina: 2003-2013.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25819541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583839
}}
* {{medline-title
|title=FDG and Amyloid PET in Cognitively Normal Individuals at Risk for Late-Onset Alzheimer's Disease.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25530915
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270202
}}
* {{medline-title
|title=Randomized trial of the ForeseeHome monitoring device for early detection of neovascular age-related macular degeneration. The HOme Monitoring of the Eye (HOME) study design - HOME Study report number 1.
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24530651
|full-text-url=https://sci-hub.do/10.1016/j.cct.2014.02.003
}}
==GDNF==
* {{medline-title
|title=GFR-α1 Expression in Substantia Nigra Increases Bilaterally Following Unilateral Striatal [[GDNF]] in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss Following 6-OHDA Nigrostriatal Lesion.
|date=16.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31538765
|full-text-url=https://sci-hub.do/10.1021/acschemneuro.9b00291
}}
* {{medline-title
|title=The Gender-Biased Effects of Intranasal MPTP Administration on Anhedonic- and Depressive-Like Behaviors in C57BL/6 Mice: the Role of Neurotrophic Factors.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808370
|full-text-url=https://sci-hub.do/10.1007/s12640-018-9912-4
}}
* {{medline-title
|title=Analysis of neurotrophic and antioxidant factors related to midbrain dopamine neuronal loss and brain inflammation in the cerebrospinal fluid of the elderly.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775745
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.009
}}
* {{medline-title
|title=Glial cell line-derived neurotrophic factor ([[GDNF]]) attenuates the peripheral neuromuscular dysfunction without inhibiting the activation of spinal microglia/monocyte.
|date=09.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29743034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944173
}}
* {{medline-title
|title=Aging-related limit of exercise efficacy on motor decline.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29176896
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703560
}}
* {{medline-title
|title=The Noradrenergic System of Aged [[GDNF]] Heterozygous Mice.
|date=04.2003
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28853928
|full-text-url=https://sci-hub.do/10.3727/000000003108746740
}}
* {{medline-title
|title=Age-associated decrease in [[GDNF]] and its cognate receptor GFRα-1 protein expression in human skin.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27346872
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960578
}}
* {{medline-title
|title=Effect of age on expression of spermatogonial markers in bovine testis and isolated cells.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27180120
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2016.04.004
}}
* {{medline-title
|title=Human neural progenitors differentiate into astrocytes and protect motor neurons in aging rats.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27032721
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2016.03.023
}}
* {{medline-title
|title=Exercise-Mediated Increase in Nigral Tyrosine Hydroxylase Is Accompanied by Increased Nigral GFR-α1 and EAAC1 Expression in Aging Rats.
|date=17.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26599339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926611
}}
* {{medline-title
|title=Mechanisms of Muscle Denervation in Aging: Insights from a Mouse Model of Amyotrophic Lateral Sclerosis.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26425392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567220
}}
* {{medline-title
|title=The involvement of [[BDNF]], [[NGF]] and [[GDNF]] in aging and Alzheimer's disease.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26425388
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567216
}}
* {{medline-title
|title=Symptomatic improvement, increased life-span and sustained cell homing in amyotrophic lateral sclerosis after transplantation of human umbilical cord blood cells genetically modified with adeno-viral vectors expressing a neuro-protective factor and a neural cell adhesion molecule.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25619885
|full-text-url=https://sci-hub.do/10.2174/1566523215666150126122317
}}
* {{medline-title
|title=Effects of aging on glutamate neurotransmission in the substantia nigra of Gdnf heterozygous mice.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25577412
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346478
}}
* {{medline-title
|title=Age and lesion-induced increases of [[GDNF]] transgene expression in brain following intracerebral injections of DNA nanoparticles.
|date=22.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25453772
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268246
}}
* {{medline-title
|title=Astrocytes show reduced support of motor neurons with aging that is accelerated in a rodent model of ALS.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25443290
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2014.09.020
}}
* {{medline-title
|title=[[GDNF]] and GFRα co-receptor family in the developing feline gut.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24834895
|full-text-url=https://sci-hub.do/10.1016/j.aanat.2014.03.001
}}
==KLF4==
* {{medline-title
|title=Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1α Activation.
|date=25.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32630449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357081
}}
* {{medline-title
|title=Soluble klotho regulates the function of salivary glands by activating [[KLF4]] pathways.
|date=02.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31581134
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814581
}}
* {{medline-title
|title=Centenarians Overexpress Pluripotency-Related Genes.
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
}}
* {{medline-title
|title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862
}}
* {{medline-title
|title=miR-10a rejuvenates aged human mesenchymal stem cells and improves heart function after myocardial infarction through [[KLF4]].
|date=30.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29848383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977543
}}
* {{medline-title
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|date=10.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
}}
* {{medline-title
|title=Kruppel-like factor 4 regulates keratinocyte senescence.
|date=05.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580988
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.172
}}
* {{medline-title
|title=Role of CD133 Molecule in Wnt Response and Renal Repair.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29431914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827750
}}
* {{medline-title
|title=Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.
|date=15.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29138277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733499
}}
* {{medline-title
|title=[[ZSCAN10]] expression corrects the genomic instability of iPSCs from aged donors.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846095
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843481
}}
* {{medline-title
|title=Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts.
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635509
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576272
}}
* {{medline-title
|title=Role of p16  and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28410532
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390672
}}
* {{medline-title
|title=Overexpression of [[KLF4]] promotes cell senescence through microRNA-203-survivin-p21 pathway.
|date=13.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27531889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312384
}}
* {{medline-title
|title=Adipose-derived stem cells from lean and obese humans show depot specific differences in their stem cell markers, exosome contents and senescence: role of protein kinase C delta (PKCδ) in adipose stem cell niche.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27358894
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923648
}}
* {{medline-title
|title=[[KLF4]] deletion alters gastric cell lineage and induces [[MUC2]] expression.
|date=09.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27277677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143387
}}
* {{medline-title
|title=Critical role of the miR-200 family in regulating differentiation and proliferation of neurons.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25753155
|full-text-url=https://sci-hub.do/10.1111/jnc.13089
}}
* {{medline-title
|title=Oxidative DNA damage causes premature senescence in mouse embryonic fibroblasts deficient for Krüppel-like factor 4.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24788960
|full-text-url=https://sci-hub.do/10.1002/mc.22161
}}
==LPO==
* {{medline-title
|title=[Features of the changes in lipid peroxidation and activity of Na /K -ATPase in the brain of the aged rats in the conditions of two-vessel cerebral ischemia/reperfusion.]
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32160433
}}
* {{medline-title
|title=Exercise training initiated at old stage of lifespan attenuates aging-and ovariectomy-induced cardiac and renal oxidative stress: Role of baroreflex.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31195102
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110635
}}
* {{medline-title
|title=Tris(1,3-dichloro-2-propyl) phosphate accelerated the aging process induced by the 4-hydroxynon-2-enal response to reactive oxidative species in Caenorhabditis elegans.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31159140
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2018.12.082
}}
* {{medline-title
|title=Physical Exercise Attenuates Oxidative Stress and Morphofunctional Cerebellar Damages Induced by the Ethanol Binge Drinking Paradigm from Adolescence to Adulthood in Rats.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398010
}}
* {{medline-title
|title=[Effect of cryopreserved cord blood nucleated cells on course of pathological processes in progressive aging of brain (experimental study).]
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30584872
}}
* {{medline-title
|title=Analysis of Plasma MicroRNAs as Predictors and Biomarkers of Aging and Frailty in Humans.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079380
}}
* {{medline-title
|title=[[ERCC1]]-deficient cells and mice are hypersensitive to lipid peroxidation.
|date=20.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098728
}}
* {{medline-title
|title=Antioxidant action of grape seed polyphenols and aerobic exercise in improving neuronal number in the hippocampus is associated with decrease in lipid peroxidation and hydrogen peroxide in adult and middle-aged rats.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29174497
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.012
}}
* {{medline-title
|title=The antioxidative and anti-aging effects of acidic- and alkalic-extractable mycelium polysaccharides by Agrocybe aegerita (Brig.) Sing.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28851637
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2017.08.138
}}
* {{medline-title
|title=Aging modifies daily variation of antioxidant enzymes and oxidative status in the hippocampus.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27940169
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.12.002
}}
* {{medline-title
|title=Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27908783
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.11.043
}}
* {{medline-title
|title=An iron-deficient diet during development induces oxidative stress in relation to age and gender in Wistar rats.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27778230
|full-text-url=https://sci-hub.do/10.1007/s13105-016-0529-x
}}
* {{medline-title
|title=Age-Dependent Changes in Na( ),K( )-ATPase Activity and Lipid Peroxidation in Membranes of Erythrocytes during Cardiosclerosis Development in Rats.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27388633
|full-text-url=https://sci-hub.do/10.1007/s10517-016-3384-4
}}
* {{medline-title
|title=Purple sweet potato anthocyanin attenuates fat-induced mortality in Drosophila melanogaster.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329928
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.06.006
}}
* {{medline-title
|title=n-3 fatty acids effectively improve the reference memory-related learning ability associated with increased brain docosahexaenoic acid-derived docosanoids in aged rats.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25450447
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2014.10.009
}}
* {{medline-title
|title=Pectinase-treated Panax ginseng extract (GINST) rescues testicular dysfunction in aged rats via redox-modulating proteins.
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24594315
|full-text-url=https://sci-hub.do/10.1016/j.exger.2014.02.012
}}
* {{medline-title
|title=Antioxidant role of oleuropein on midbrain and dopaminergic neurons of substantia nigra in aged rats.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24375158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892135
}}
==MTR==
* {{medline-title
|title=Amide proton transfer-weighted magnetic resonance imaging of human brain aging at 3 Tesla.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32269932
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136735
}}
* {{medline-title
|title=One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208817
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.05.013
}}
* {{medline-title
|title=Test-retest reliability of myelin imaging in the human spinal cord: Measurement errors versus region- and aging-induced variations.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29293550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749716
}}
* {{medline-title
|title=Alterations in brain white matter contributing to age-related slowing of task switching performance: The role of radial diffusivity and magnetization transfer ratio.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27571231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867406
}}
* {{medline-title
|title=Development and aging of superficial white matter myelin from young adulthood to old age: Mapping by vertex-based surface statistics (VBSS).
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26955787
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472924
}}
* {{medline-title
|title=Moderate treadmill running exercise prior to tendon injury enhances wound healing in aging rats.
|date=23.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26885754
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890982
}}
* {{medline-title
|title=Nutritional habits, lifestyle, and genetic predisposition in cardiovascular and metabolic traits in Turkish population.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26856649
|full-text-url=https://sci-hub.do/10.1016/j.nut.2015.12.027
}}
* {{medline-title
|title=Age-effects in white matter using associated diffusion tensor imaging and magnetization transfer ratio during late childhood and early adolescence.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26708037
|full-text-url=https://sci-hub.do/10.1016/j.mri.2015.12.021
}}
* {{medline-title
|title=Associations between insulin action and integrity of brain microstructure differ with familial longevity and with age.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26074813
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446544
}}
* {{medline-title
|title=An in vivo study on brain microstructure in biological and chronological ageing.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25807271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373824
}}
* {{medline-title
|title=White matter hyperintensities and normal-appearing white matter integrity in the aging brain.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25457555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321830
}}
* {{medline-title
|title=Structural covariance of superficial white matter in mild Alzheimer's disease compared to normal aging.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25328848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113976
}}
* {{medline-title
|title=Magnetization transfer ratio relates to cognitive impairment in normal elderly.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25309438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174770
}}
* {{medline-title
|title=Gender, age-related, and regional differences of the magnetization transfer ratio of the cortical and subcortical brain gray matter.
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24923993
|full-text-url=https://sci-hub.do/10.1002/jmri.24355
}}
* {{medline-title
|title=Age independently affects myelin integrity as detected by magnetization transfer magnetic resonance imaging in multiple sclerosis.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24936415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053639
}}
* {{medline-title
|title=Magnetization transfer imaging for in vivo detection of microstructural tissue changes in aging and dementia: a short literature review.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24840568
|full-text-url=https://sci-hub.do/10.3233/JAD-132750
}}
* {{medline-title
|title=Quantitative multi-modal MRI of the Hippocampus and cognitive ability in community-dwelling older subjects.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24561387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979658
}}
==NOX4==
* {{medline-title
|title=Sestrin2 Attenuates Cellular Senescence by Inhibiting NADPH Oxidase 4 Expression.
|date=24.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33227845
|full-text-url=https://sci-hub.do/10.4235/agmr.20.0051
}}
* {{medline-title
|title=NADPH Oxidases and Aging Models of Lung Fibrosis.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31172491
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-9424-3_29
}}
* {{medline-title
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
}}
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
* {{medline-title
|title=Redox Imbalance in Idiopathic Pulmonary Fibrosis: A Role for Oxidant Cross-Talk Between NADPH Oxidase Enzymes and Mitochondria.
|date=10.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30793932
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767863
}}
* {{medline-title
|title=NADPH oxidase 4 mediates ROS production in radiation-induced senescent cells and promotes migration of inflammatory cells.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228832
|full-text-url=https://sci-hub.do/10.1080/10715762.2017.1416112
}}
* {{medline-title
|title=Alternative Splicing of [[NOX4]] in the Failing Human Heart.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29204124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698687
}}
* {{medline-title
|title=Cooperation between p21 and Akt is required for p53-dependent cellular senescence.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28691365
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595696
}}
* {{medline-title
|title=Mcl-1 regulates reactive oxygen species via [[NOX4]] during chemotherapy-induced senescence.
|date=25.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28423654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438639
}}
* {{medline-title
|title=PPARα activation by MHY908 attenuates age-related renal inflammation through modulation of the ROS/Akt/FoxO1 pathway.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28323024
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.03.015
}}
* {{medline-title
|title=NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27986445
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625334
}}
* {{medline-title
|title=[[NOX4]] downregulation leads to senescence of human vascular smooth muscle cells.
|date=11.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27655718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341811
}}
* {{medline-title
|title=Reactive oxygen species: The good, the bad, and the enigma.
|date=07-09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27308352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904994
}}
* {{medline-title
|title=Interferon gamma/NADPH oxidase defense system in immunity and cancer.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27057461
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801460
}}
* {{medline-title
|title=[[NOS1]] induces NADPH oxidases and impairs contraction kinetics in aged murine ventricular myocytes.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26173391
|full-text-url=https://sci-hub.do/10.1007/s00395-015-0506-5
}}
* {{medline-title
|title=[[NOX4]] NADPH Oxidase-Dependent Mitochondrial Oxidative Stress in Aging-Associated Cardiovascular Disease.
|date=20.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26054376
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692134
}}
* {{medline-title
|title=The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4.
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24632182
|full-text-url=https://sci-hub.do/10.1016/j.exger.2014.03.005
}}
==PARP1==
* {{medline-title
|title=Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285747
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591813
}}
* {{medline-title
|title=[[PARP1]] inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD  levels and increasing [[SIRT1]] activity.
|date=23.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30139380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107962
}}
* {{medline-title
|title=Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice.
|date=13.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29137352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663524
}}
* {{medline-title
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
}}
* {{medline-title
|title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417
}}
* {{medline-title
|title=The NAD /[[PARP1]]/[[SIRT1]] Axis in Aging.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28537485
|full-text-url=https://sci-hub.do/10.1089/rej.2017.1980
}}
* {{medline-title
|title=A conserved NAD  binding pocket that regulates protein-protein interactions during aging.
|date=24.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28336669
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456119
}}
* {{medline-title
|title=Melatonin regulates [[PARP1]] to control the senescence-associated secretory phenotype (SASP) in human fetal lung fibroblast cells.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28247536
|full-text-url=https://sci-hub.do/10.1111/jpi.12405
}}
* {{medline-title
|title=The Ubiquitin-like with PHD and Ring Finger Domains 1 ([[UHRF1]])/DNA Methyltransferase 1 ([[DNMT1]]) Axis Is a Primary Regulator of Cell Senescence.
|date=03.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28100769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339756
}}
* {{medline-title
|title=A serum miRNA profile of human longevity: findings from the Baltimore Longitudinal Study of Aging (BLSA).
|date=07.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27824314
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191881
}}
* {{medline-title
|title=Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA.
|date=01.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27791127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098674
}}
* {{medline-title
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
}}
* {{medline-title
|title=Differential cytotoxicity induced by the Titanium(IV)Salan complex Tc52 in G2-phase independent of DNA damage.
|date=13.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27412346
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944496
}}
* {{medline-title
|title=All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype.
|date=06.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26359359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745772
}}
* {{medline-title
|title=SIRT6 rescues the age related decline in base excision repair in a [[PARP1]]-dependent manner.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25607651
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614943
}}
* {{medline-title
|title=RecQ helicases and [[PARP1]] team up in maintaining genome integrity.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25555679
|full-text-url=https://sci-hub.do/10.1016/j.arr.2014.12.006
}}
* {{medline-title
|title=Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1.
|date=03.06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24843141
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050581
}}
==ADAM10==
* {{medline-title
|title=NKG2D Ligand Shedding in Response to Stress: Role of [[ADAM10]].
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32269567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109295
}}
* {{medline-title
|title=Chronic Mild Stress Modified Epigenetic Mechanisms Leading to Accelerated Senescence and Impaired Cognitive Performance in Mice.
|date=10.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32050516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037343
}}
* {{medline-title
|title=Removal of p75 Neurotrophin Receptor Expression from Cholinergic Basal Forebrain Neurons Reduces Amyloid-β Plaque Deposition and Cognitive Impairment in Aged APP/PS1 Mice.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30374941
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1404-2
}}
* {{medline-title
|title=11β-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29611102
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1026-8
}}
* {{medline-title
|title=Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells.
|date=15.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29348391
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811245
}}
* {{medline-title
|title=microRNA 221 Targets [[ADAM10]] mRNA and is Downregulated in Alzheimer's Disease.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29036829
|full-text-url=https://sci-hub.do/10.3233/JAD-170592
}}
* {{medline-title
|title=Human Plasma Thioredoxin-80 Increases With Age and in ApoE  Mice Induces Inflammation, Angiogenesis, and Atherosclerosis.
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473446
|full-text-url=https://sci-hub.do/10.1161/CIRCULATIONAHA.117.027612
}}
* {{medline-title
|title=Ionizing radiation reduces [[ADAM10]] expression in brain microvascular endothelial cells undergoing stress-induced senescence.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28437250
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425125
}}
* {{medline-title
|title=Regulation of Alpha-Secretase [[ADAM10]] [i]In vitro[/i] and [i]In vivo[/i]: Genetic, Epigenetic, and Protein-Based Mechanisms.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28367112
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355436
}}
* {{medline-title
|title=Sideritis spp. Extracts Enhance Memory and Learning in Alzheimer's β-Amyloidosis Mouse Models and Aged C57Bl/6 Mice.
|date=31.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27258424
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981905
}}
* {{medline-title
|title=Effects of Sesaminol Feeding on Brain Aβ Accumulation in a Senescence-Accelerated Mouse-Prone 8.
|date=22.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27233432
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.6b01237
}}
* {{medline-title
|title=Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27094468
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.014
}}
* {{medline-title
|title=Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27013617
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925821
}}
* {{medline-title
|title=Increase of α-Secretase [[ADAM10]] in Platelets Along Cognitively Healthy Aging.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26757187
|full-text-url=https://sci-hub.do/10.3233/JAD-150737
}}
* {{medline-title
|title=[[ADAM10]] gene expression in the blood cells of Alzheimer's disease patients and mild cognitive impairment subjects.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26220620
|full-text-url=https://sci-hub.do/10.3109/1354750X.2015.1062554
}}
* {{medline-title
|title=Serum Fragments of Tau for the Differential Diagnosis of Alzheimer's Disease.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26159200
|full-text-url=https://sci-hub.do/10.2174/1567205012666150710111211
}}
==ALDH2==
* {{medline-title
|title=Aldehyde Dehydrogenase 2 ([[ALDH2]]) and Aging: Is There a Sensible Link?
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31368109
|full-text-url=https://sci-hub.do/10.1007/978-981-13-6260-6_15
}}
* {{medline-title
|title=Appropriate dose of ethanol exerts anti-senescence and anti-atherosclerosis protective effects by activating [[ALDH2]].
|date=30.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885430
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.03.037
}}
* {{medline-title
|title=Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472277
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.013
}}
* {{medline-title
|title=Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466069
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2018.11.007
}}
* {{medline-title
|title=Aldehyde dehydrogenase 2 deficiency promotes atherosclerotic plaque instability through accelerating mitochondrial ROS-mediated vascular smooth muscle cell senescence.
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30315930
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.09.033
}}
* {{medline-title
|title=[[ALDH2]] mediates the dose-response protection of chronic ethanol against endothelial senescence through [[SIRT1]]/p53 pathway.
|date=12.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217444
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.081
}}
* {{medline-title
|title=Effects of the common polymorphism in the human aldehyde dehydrogenase 2 ([[ALDH2]]) gene on the lung.
|date=21.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28431562
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399815
}}
* {{medline-title
|title=Complex inhibition of autophagy by mitochondrial aldehyde dehydrogenase shortens lifespan and exacerbates cardiac aging.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28347844
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2017.03.016
}}
* {{medline-title
|title=Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27094468
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.014
}}
* {{medline-title
|title=Associations Between Alcohol Consumption and Leukocyte Telomere Length Modified by a Common Polymorphism of [[ALDH2]].
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26972231
|full-text-url=https://sci-hub.do/10.1111/acer.13005
}}
* {{medline-title
|title=Relationships of alcohol dehydrogenase 1B ([[ADH1B]]) and aldehyde dehydrogenase 2 ([[ALDH2]]) genotypes with alcohol sensitivity, drinking behavior and problem drinking in Japanese older men.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26825972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823221
}}
* {{medline-title
|title=Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on [[SIRT1]].
|date=19.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26741505
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823027
}}
* {{medline-title
|title=Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease.
|date=25.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25910195
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409701
}}
* {{medline-title
|title=Ethanol reduces lifespan, body weight, and serum alanine aminotransferase level of aldehyde dehydrogenase 2 knockout mouse.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24930774
|full-text-url=https://sci-hub.do/10.1111/acer.12462
}}
* {{medline-title
|title=Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24675227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068748
}}
* {{medline-title
|title=Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.
|date=01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24382882
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929114
}}
==BCR==
* {{medline-title
|title=The presence of CLL-associated stereotypic B cell receptors in the normal [[BCR]] repertoire from healthy individuals increases with age.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31485252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714092
}}
* {{medline-title
|title=Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930899
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428705
}}
* {{medline-title
|title=Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30487792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246921
}}
* {{medline-title
|title=B cell responses to apoptotic cells in MFG-E8-/- mice.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30286201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171925
}}
* {{medline-title
|title=Early Generated B-1-Derived B Cells Have the Capacity To Progress To Become Mantle Cell Lymphoma-like Neoplasia in Aged Mice.
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036230
}}
* {{medline-title
|title=Mean residual life regression with functional principal component analysis on longitudinal data for dynamic prediction.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29601636
|full-text-url=https://sci-hub.do/10.1111/biom.12876
}}
* {{medline-title
|title=NLR Nod1 signaling promotes survival of [[BCR]]-engaged mature B cells through up-regulated Nod1 as a positive outcome.
|date=02.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28878001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626402
}}
* {{medline-title
|title=Phylogenetic analysis of the human antibody repertoire reveals quantitative signatures of immune senescence and aging.
|date=31.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28096374
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293037
}}
* {{medline-title
|title=Immunosenescence-Related Transcriptomic and Immunologic Changes in Older Individuals Following Influenza Vaccination.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27853459
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089977
}}
* {{medline-title
|title=4-methylumbelliferone and imatinib combination enhances senescence induction in chronic myeloid leukemia cell lines.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27718039
|full-text-url=https://sci-hub.do/10.1007/s10637-016-0397-9
}}
* {{medline-title
|title=Hyaluronan oligomers sensitize chronic myeloid leukemia cell lines to the effect of Imatinib.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26582603
|full-text-url=https://sci-hub.do/10.1093/glycob/cwv107
}}
* {{medline-title
|title=Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26551682
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665776
}}
* {{medline-title
|title=The ageing human B cell repertoire: a failure of selection?
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26332693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687518
}}
* {{medline-title
|title=Age stratified comparative analysis of perioperative, functional and oncologic outcomes in patients after robot assisted radical prostatectomy--A propensity score matched study.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25980748
|full-text-url=https://sci-hub.do/10.1016/j.ejso.2015.04.006
}}
* {{medline-title
|title=Double negative (CD19 IgG IgD-[[CD27]]-) B lymphocytes: a new insight from telomerase in healthy elderly, in centenarian offspring and in Alzheimer's disease patients.
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951896
|full-text-url=https://sci-hub.do/10.1016/j.imlet.2014.06.003
}}
* {{medline-title
|title=Memory B cells form in aged mice despite impaired affinity maturation and germinal center kinetics.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24389058
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989373
}}
==CD19==
* {{medline-title
|title=Sequential treatment with aT19 cells generates memory CAR-T cells and prolongs the lifespan of Raji-B-NDG mice.
|date=28.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634527
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2019.10.022
}}
* {{medline-title
|title=Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma
|date=18.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863019
}}
* {{medline-title
|title=Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30408092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224077
}}
* {{medline-title
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|date=05.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
}}
* {{medline-title
|title=Vitamin D levels correlate with lymphocyte subsets in elderly patients with age-related diseases.
|date=16.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956012
}}
* {{medline-title
|title=Normal variation of bone marrow B-cell precursors according to age - reference ranges for studies in myelodysplastic syndromes in Brazil.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29205788
|full-text-url=https://sci-hub.do/10.1002/cyto.b.21604
}}
* {{medline-title
|title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses.
|date=17.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542
}}
* {{medline-title
|title=Different therapeutic effects of cells derived from human amniotic membrane on premature ovarian aging depend on distinct cellular biological characteristics.
|date=27.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28750654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530953
}}
* {{medline-title
|title=Immune biomarkers in older adults: Role of physical activity.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28524767
|full-text-url=https://sci-hub.do/10.1080/15287394.2017.1286898
}}
* {{medline-title
|title=A lifetime aging study of human [[CD19]] transgenic mice.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28243835
|full-text-url=https://sci-hub.do/10.1007/s11248-017-0010-9
}}
* {{medline-title
|title=Age-related arterial immune cell infiltration in mice is attenuated by caloric restriction or voluntary exercise.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28012941
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481497
}}
* {{medline-title
|title=Alterations in B-cell subsets in pediatric patients with early atopic dermatitis.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27965110
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2016.09.060
}}
* {{medline-title
|title=Perturbed hematopoiesis in mice lacking [[ATM]]IN.
|date=20.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27581360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147016
}}
* {{medline-title
|title=Effects of Ageing on the Immune System: Infants to Elderly.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26808160
|full-text-url=https://sci-hub.do/10.1111/sji.12413
}}
* {{medline-title
|title=Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26193622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853027
}}
* {{medline-title
|title=[Effects of soluble egg antigen and adult worm antigen of Schistosoma japonicum on differentiation of effector B cells of mice].
|date=10.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24490359
}}
==CDK2==
* {{medline-title
|title=p57  is a master regulator of human adipose derived stem cell quiescence and senescence.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32224418
|full-text-url=https://sci-hub.do/10.1016/j.scr.2020.101759
}}
* {{medline-title
|title=Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
|date=22.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31112603
|full-text-url=https://sci-hub.do/10.1093/gerona/glz077
}}
* {{medline-title
|title=Cyclin-Dependent Kinase 2 in Cellular Senescence and Cancer. A Structural and Functional Review.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30516105
|full-text-url=https://sci-hub.do/10.2174/1389450120666181204165344
}}
* {{medline-title
|title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes.
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186
}}
* {{medline-title
|title=Relationship between intermuscular adipose tissue infiltration and myostatin before and after aerobic exercise training.
|date=01.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734080
}}
* {{medline-title
|title=Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29405784
|full-text-url=https://sci-hub.do/10.1080/21691401.2018.1434187
}}
* {{medline-title
|title=Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress.
|date=20.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325896
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.01.007
}}
* {{medline-title
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|date=08.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
}}
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
* {{medline-title
|title=Pneumolysin induces cellular senescence by increasing ROS production and activation of MAPK/NF-κB signal pathway in glial cells.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28232188
|full-text-url=https://sci-hub.do/10.1016/j.toxicon.2017.02.017
}}
* {{medline-title
|title=The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging.
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27699588
|full-text-url=https://sci-hub.do/10.1007/s11010-016-2836-5
}}
* {{medline-title
|title=A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1.
|date=27.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27542238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325331
}}
* {{medline-title
|title=Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26987798
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383204
}}
* {{medline-title
|title=Double staining of β-galactosidase with fibrosis and cancer markers reveals the chronological appearance of senescence in liver carcinogenesis induced by diethylnitrosamine.
|date=22.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26589970
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2015.11.011
}}
* {{medline-title
|title=Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26253138
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577010
}}
* {{medline-title
|title=Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25815289
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356162
}}
==CDK6==
* {{medline-title
|title=Saturated Fatty Acids Promote Hepatocytic Senecence through Regulation of miR-34a/Cyclin-Dependent Kinase 6.
|date=24.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32970940
|full-text-url=https://sci-hub.do/10.1002/mnfr.202000383
}}
* {{medline-title
|title=Hepatoprotective effects of hydroxysafflor yellow A in D-galactose-treated aging mice.
|date=15.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32454116
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2020.173214
}}
* {{medline-title
|title=Anti-cell growth and anti-cancer stem cell activity of the CDK4/6 inhibitor palbociclib in breast cancer cells.
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31823286
|full-text-url=https://sci-hub.do/10.1007/s12282-019-01035-5
}}
* {{medline-title
|title=Compromising the constitutive p16  expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31692039
|full-text-url=https://sci-hub.do/10.1002/jcb.29493
}}
* {{medline-title
|title=Palbociclib Effectively Halts Proliferation but Fails to Induce Senescence in Patient-Derived Glioma Stem Cells.
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31124078
|full-text-url=https://sci-hub.do/10.1007/s12035-019-1633-z
}}
* {{medline-title
|title=Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth.
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888162
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b00833
}}
* {{medline-title
|title=Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29405784
|full-text-url=https://sci-hub.do/10.1080/21691401.2018.1434187
}}
* {{medline-title
|title=Preclinical characterization of abemaciclib in hormone receptor positive breast cancer.
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29050219
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642494
}}
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
* {{medline-title
|title=Genome-Wide Overexpression Screen Identifies Genes Able to Bypass p16-Mediated Senescence in Melanoma.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27872202
|full-text-url=https://sci-hub.do/10.1177/1087057116679592
}}
* {{medline-title
|title=p16INK4a suppresses [[BRCA1]]-deficient mammary tumorigenesis.
|date=20.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27811360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356676
}}
* {{medline-title
|title=A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1.
|date=27.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27542238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325331
}}
* {{medline-title
|title=[[CDK4]]-[[CDK6]] inhibitors induce autophagy-mediated degradation of [[DNMT1]] and facilitate the senescence antitumor response.
|date=02.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27532423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079664
}}
* {{medline-title
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
}}
* {{medline-title
|title=MicroRNA-33 promotes the replicative senescence of mouse embryonic fibroblasts by suppressing [[CDK6]].
|date=13.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27059142
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.04.016
}}
* {{medline-title
|title=MiR-506 suppresses proliferation and induces senescence by directly targeting the [[CDK4]]/6-[[FOXM1]] axis in ovarian cancer.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24604117
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144705
}}
==CX3CR1==
* {{medline-title
|title=Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32107839
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189998
}}
* {{medline-title
|title=Muscle Injury Induces Postoperative Cognitive Dysfunction.
|date=17.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32066806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026159
}}
* {{medline-title
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
}}
* {{medline-title
|title=Surgical Trauma Exacerbates Cognitive Deficits and Neuroinflammation in Aged Rats: The Role of [[CX3CL1]]-[[CX3CR1]] Signaling.
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29939299
|full-text-url=https://sci-hub.do/10.1093/jnen/nly051
}}
* {{medline-title
|title=Repopulating retinal microglia restore endogenous organization and function under [[CX3CL1]]-[[CX3CR1]] regulation.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750189
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943055
}}
* {{medline-title
|title=Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624852
|full-text-url=https://sci-hub.do/10.1002/cyto.a.23372
}}
* {{medline-title
|title=Microglia and Aging: The Role of the [[TREM2]]-DAP12 and [[CX3CL1]]-[[CX3CR1]] Axes.
|date=22.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29361745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796261
}}
* {{medline-title
|title=Strain specificities in age-related changes in mechanisms promoting and controlling rat spinal cord damage in experimental autoimmune encephalomyelitis.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29128575
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.002
}}
* {{medline-title
|title=Sex as a determinant of age-related changes in rat spinal cord inflammation-oxidation state.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825141
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9726-4
}}
* {{medline-title
|title=Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists.
|date=15.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28696254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548610
}}
* {{medline-title
|title=Transcriptomic analysis of purified human cortical microglia reveals age-associated changes.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671693
|full-text-url=https://sci-hub.do/10.1038/nn.4597
}}
* {{medline-title
|title=Phenotypic characteristics of aged [[CD4]]  [[CD28]]  T lymphocytes are determined by changes in the whole-genome DNA methylation pattern.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28026094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334526
}}
* {{medline-title
|title=Age exacerbates the [[CCR2]]/5-mediated neuroinflammatory response to traumatic brain injury.
|date=18.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27090212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835854
}}
* {{medline-title
|title=Alterations in Monocyte Phenotypes and Functions after a Hip Fracture in Elderly Individuals: A 6-Month Longitudinal Study.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26812523
|full-text-url=https://sci-hub.do/10.1159/000443142
}}
* {{medline-title
|title=Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques.
|date=29.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25630253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311408
}}
* {{medline-title
|title=Alterations to the frequency and function of peripheral blood monocytes and associations with chronic disease in the advanced-age, frail elderly.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25105870
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126708
}}
==ECD==
* {{medline-title
|title=Outcome of Descemet Membrane Endothelial Keratoplasty Using Corneas from Donors ≥80 Years of Age.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31837315
|full-text-url=https://sci-hub.do/10.1016/j.ajo.2019.12.001
}}
* {{medline-title
|title=The occurrence and dynamics of polychlorinated hydrocarbons in roe deer ([i]Capreolus capreolus[/i]) in South-western Slovakia.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30729857
|full-text-url=https://sci-hub.do/10.1080/10934529.2019.1574152
}}
* {{medline-title
|title=Corneal thickness, endothelial cell density, and morphological and morphometric features of corneal endothelial cells in goats.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30256142
|full-text-url=https://sci-hub.do/10.2460/ajvr.79.10.1087
}}
* {{medline-title
|title=Endothelial cell density and characterization of corneal endothelial cells in the Tawny Owl (Strix aluco) using specular microscopy.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29762889
|full-text-url=https://sci-hub.do/10.1111/vop.12578
}}
* {{medline-title
|title=An autopsy case report: Differences in radiological images correlate with histology in Erdheim-Chester disease.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603831
|full-text-url=https://sci-hub.do/10.1111/pin.12663
}}
* {{medline-title
|title=Community-based trials of mobile solutions for the detection and management of cognitive decline.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28706726
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496464
}}
* {{medline-title
|title=Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28617862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472294
}}
* {{medline-title
|title=A novel method for examining corneal endothelial cell morphology in infants.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28347727
|full-text-url=https://sci-hub.do/10.1016/j.jaapos.2017.01.002
}}
* {{medline-title
|title=Analyses of Factors Affecting Endothelial Cell Density in an Eye Bank Corneal Donor Database.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27310882
|full-text-url=https://sci-hub.do/10.1097/ICO.0000000000000921
}}
* {{medline-title
|title=Morphological Abnormalities of Schlemm's Canal in Primary Open-Angle Glaucoma From the Aspect of Aging.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26903228
|full-text-url=https://sci-hub.do/10.1167/iovs.15-17127
}}
* {{medline-title
|title=[TEMPORAL ORDER DETERIORATION AND CIRCADIAN DISRUPTION WITH AGE].
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26856086
}}
* {{medline-title
|title=Age-Dependent Changes of the Temporal Order--Causes and Treatment.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26632427
|full-text-url=https://sci-hub.do/10.2174/1874609809666151130215824
}}
* {{medline-title
|title=Pathogenesis of endothelial cell dysfunction in chronic kidney disease: a retrospective and what the future may hold.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26484026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570605
}}
* {{medline-title
|title=Specular microscopy to determine corneal endothelial cell morphology and morphometry in chinchillas (Chinchilla lanigera) in vivo.
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25469785
|full-text-url=https://sci-hub.do/10.1111/vop.12236
}}
* {{medline-title
|title=Oncogene-induced senescence as a new mechanism of disease: the paradigm of erdheim-chester disease.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24982657
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056107
}}
* {{medline-title
|title=Comparison of endothelial cell density of organ cultured corneas with cornea donor study.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24809309
|full-text-url=https://sci-hub.do/10.1097/ICO.0000000000000124
}}
==HDAC1==
* {{medline-title
|title=[[HDAC1]] modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease.
|date=18.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235043
}}
* {{medline-title
|title=Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30886000
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446199
}}
* {{medline-title
|title=Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies.
|date=20.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30341976
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224233
}}
* {{medline-title
|title=Acetylation of PGC1α by Histone Deacetylase 1 Downregulation Is Implicated in Radiation-Induced Senescence of Brain Endothelial Cells.
|date=16.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30016403
|full-text-url=https://sci-hub.do/10.1093/gerona/gly167
}}
* {{medline-title
|title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771
}}
* {{medline-title
|title=Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-[[HDAC1]]-mediated regulation of autophagy.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660306
|full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2018.04.009
}}
* {{medline-title
|title=Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment.
|date=30.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28415598
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482635
}}
* {{medline-title
|title=Epigallocatechin gallate reverses cTnI-low expression-induced age-related heart diastolic dysfunction through histone acetylation modification.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28382690
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618683
}}
* {{medline-title
|title=Emerging roles for histone deacetylases in age-related muscle atrophy.
|date=27.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28035339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166515
}}
* {{medline-title
|title=[i]Rpd3[/i] interacts with insulin signaling in [i]Drosophila[/i] longevity extension.
|date=14.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27852975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191884
}}
* {{medline-title
|title=Expression of non-secreted IL-4 is associated with HDAC inhibitor-induced cell death, histone acetylation and c-Jun regulation in human gamma/delta T-cells.
|date=04.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27556516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323112
}}
* {{medline-title
|title=The effects of Rpd3 on fly metabolism, health, and longevity.
|date=15.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26927903
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002259
}}
* {{medline-title
|title=Parthenolide induces [[MITF]]-M downregulation and senescence in patient-derived [[MITF]]-M(high) melanoma cell populations.
|date=23.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26824319
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891023
}}
* {{medline-title
|title=Scopoletin has a potential activity for anti-aging via autophagy in human lung fibroblasts.
|date=15.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25837273
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2015.01.004
}}
* {{medline-title
|title=De-regulated expression of the BRG1 chromatin remodeling factor in bone marrow mesenchymal stromal cells induces senescence associated with the silencing of NANOG and changes in the levels of chromatin proteins.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25724006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614278
}}
* {{medline-title
|title=Lysine deacetylases regulate the heat shock response including the age-associated impairment of HSF1.
|date=10.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25688804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357550
}}
==IL10==
* {{medline-title
|title=The beneficial effect of physical exercise on inflammatory makers in older individuals.
|date=06.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32504508
|full-text-url=https://sci-hub.do/10.2174/1871530320666200606225357
}}
* {{medline-title
|title=Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14 , and TAU3 transcript expression and contribute to cognitive decline.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654269
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885035
}}
* {{medline-title
|title=Dietary Spray-Dried Porcine Plasma Prevents Cognitive Decline in Senescent Mice and Reduces Neuroinflammation and Oxidative Stress.
|date=01.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562503
|full-text-url=https://sci-hub.do/10.1093/jn/nxz239
}}
* {{medline-title
|title=Age-dependent hepatic alterations induced by a high-fat high-fructose diet.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30874869
|full-text-url=https://sci-hub.do/10.1007/s00011-019-01223-1
}}
* {{medline-title
|title=[i]Lactobacillus paracasei[/i] PS23 decelerated age-related muscle loss by ensuring mitochondrial function in SAMP8 mice.
|date=29.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696799
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366975
}}
* {{medline-title
|title=Inflammatory cytokines and immune system modulation by aerobic versus resisted exercise training for elderly.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29977265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016983
}}
* {{medline-title
|title=Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29715306
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929513
}}
* {{medline-title
|title=Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia.
|date=01.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756472
}}
* {{medline-title
|title=The role of gender and labour status in immunosenescence of 65  Polish population.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28444479
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514219
}}
* {{medline-title
|title=Serum Immune Mediators Independently Associate with Atherosclerosis in the Left (But Not Right) Carotid Territory of Older Individuals.
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27554076
|full-text-url=https://sci-hub.do/10.1016/j.jstrokecerebrovasdis.2016.07.047
}}
* {{medline-title
|title=[[IL10]]-driven [[STAT3]] signalling in senescent macrophages promotes pathological eye angiogenesis.
|date=11.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26260587
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918330
}}
* {{medline-title
|title=Development of depressive symptoms post hip fracture is associated with altered immunosuppressive phenotype in regulatory T and B lymphocytes.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26112234
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723613
}}
* {{medline-title
|title=LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26087730
}}
* {{medline-title
|title=The effect of astaxanthin on the aging rat brain: gender-related differences in modulating inflammation.
|date=30.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25678261
|full-text-url=https://sci-hub.do/10.1002/jsfa.7131
}}
* {{medline-title
|title=Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24791650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163500
}}
* {{medline-title
|title=Oral delivery of glutamic acid decarboxylase (GAD)-65 and [[IL10]] by Lactococcus lactis reverses diabetes in recent-onset NOD mice.
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24677716
|full-text-url=https://sci-hub.do/10.2337/db13-1236
}}
==INS==
* {{medline-title
|title=Melatonin protects [[INS]]-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity.
|date=03.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32673151
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527021
}}
* {{medline-title
|title=Nicotine triggers islet β cell senescence to facilitate the progression of type 2 diabetes.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32473187
|full-text-url=https://sci-hub.do/10.1016/j.tox.2020.152502
}}
* {{medline-title
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading.
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869
}}
* {{medline-title
|title=Insulin-like peptides and the mTOR-[[TFEB]] pathway protect [i]Caenorhabditis elegans[/i] hermaphrodites from mating-induced death.
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697448
}}
* {{medline-title
|title=The Maghreb demographic transition: Tunisia case study.
|date=10-11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30746669
}}
* {{medline-title
|title=Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30456853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351846
}}
* {{medline-title
|title=A functional study of all 40 [i]Caenorhabditis elegans[/i] insulin-like peptides.
|date=26.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206121
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204898
}}
* {{medline-title
|title=The anti-aging protein Klotho is induced by GABA therapy and exerts protective and stimulatory effects on pancreatic beta cells.
|date=02.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28993191
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.10.029
}}
* {{medline-title
|title=Increase of Calcium Sensing Receptor Expression Is Related to Compensatory Insulin Secretion during Aging in Mice.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27441644
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956240
}}
* {{medline-title
|title=Food-derived sensory cues modulate longevity via distinct neuroendocrine insulin-like peptides.
|date=01.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27125673
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863736
}}
* {{medline-title
|title=Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of [[INS]]-1 cells through Pim-1.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27049278
}}
* {{medline-title
|title=Accommodative movements of the lens/capsule and the strand that extends between the posterior vitreous zonule insertion zone

Текущая версия от 13:26, 6 апреля 2021

CCL2[править]

  • β1 Integrin regulates adult lung alveolar epithelial cell inflammation. / 30.01.2020 / PubMed / Full text
  • Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. / 07.2019 / PubMed / Full text
  • Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic PIK3CA accompanied with pro-tumorigenic secretome. / 01.08.2019 / PubMed / Full text
  • Isoflurane anesthesia impairs the expression of immune neuromodulators in the hippocampus of aged mice. / 2018 / PubMed / Full text
  • Melatonin and inflammation-Story of a double-edged blade. / 11.2018 / PubMed / Full text
  • Defective autophagy in vascular smooth muscle cells enhances cell death and atherosclerosis. / 2018 / PubMed / Full text
  • Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age. / 09.2018 / PubMed / Full text
  • Infiltrating macrophages contribute to age-related neuroinflammation in C57/BL6 mice. / 07.2018 / PubMed / Full text
  • Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles. / 05.2018 / PubMed / Full text
  • Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor. / 2018 / PubMed / Full text
  • Immune senescence and biomarkers profile of Bambuí aged population-based cohort. / 03.2018 / PubMed / Full text
  • Selected life-extending interventions reduce arterial CXCL10 and macrophage colony-stimulating factor in aged mouse arteries. / 08.2017 / PubMed / Full text
  • Strain specificities in cellular and molecular immunopathogenic mechanisms underlying development of experimental autoimmune encephalomyelitis in aged rats. / 06.2017 / PubMed / Full text
  • Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension. / 02.2017 / PubMed / Full text
  • An attenuated immune response by Schwann cells and macrophages inhibits nerve regeneration in aged rats. / 09.2016 / PubMed / Full text
  • Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging. / 04.2016 / PubMed / Full text
  • Agmatine Ameliorates High Glucose-Induced Neuronal Cell Senescence by Regulating the p21 and p53 Signaling. / 02.2016 / PubMed / Full text
  • Alterations in Monocyte Phenotypes and Functions after a Hip Fracture in Elderly Individuals: A 6-Month Longitudinal Study. / 2016 / PubMed / Full text
  • Elevated Levels of Microbial Translocation Markers and CCL2 Among Older HIV-1-Infected Men. / 01.03.2016 / PubMed / Full text
  • APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration. / 07.10.2015 / PubMed / Full text
  • Colorectal cancer-promoting activity of the senescent peritoneal mesothelium. / 06.10.2015 / PubMed / Full text
  • Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models. / 24.09.2015 / PubMed / Full text
  • Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age. / 2015 / PubMed / Full text
  • Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. / 2015 / PubMed / Full text
  • CCL2, CXCL8, CXCL9 and CXCL10 serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees. / 12.2017 / PubMed / Full text
  • Senescent dermal fibroblasts enhance stem cell migration through CCL2/CCR2 axis. / 07.2015 / PubMed / Full text
  • Age-associated changes in basal NF-κB function in human CD4 T lymphocytes via dysregulation of PI3 kinase. / 11.2014 / PubMed / Full text
  • IL-4 signaling drives a unique arginase /IL-1β microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Rα after traumatic spinal cord injury. / 25.06.2014 / PubMed / Full text
  • Systemic inflammation impairs attention and cognitive flexibility but not associative learning in aged rats: possible implications for delirium. / 2014 / PubMed / Full text

EGFR[править]

  • Type I Collagen Aging Increases Expression and Activation of EGFR and Induces Resistance to Erlotinib in Lung Carcinoma in 3D Matrix Model. / 2020 / PubMed / Full text
  • Comparative effectiveness and cost-effectiveness of three first-line EGFR-tyrosine kinase inhibitors: Analysis of real-world data in a tertiary hospital in Taiwan. / 2020 / PubMed / Full text
  • An Optogenetic Method to Study Signal Transduction in Intestinal Stem Cell Homeostasis. / 01.05.2020 / PubMed / Full text
  • Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. / 13.01.2020 / PubMed / Full text
  • Association between EGFR mutation and ageing, history of pneumonia and gastroesophageal reflux disease among patients with advanced lung cancer. / 11.2019 / PubMed / Full text
  • Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. / 22.07.2019 / PubMed / Full text
  • The role of EGFR signaling in age-related osteoporosis in mouse cortical bone. / 10.2019 / PubMed / Full text
  • Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes. / 13.06.2019 / PubMed / Full text
  • EGF/EGFR upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence. / 04.12.2018 / PubMed / Full text
  • An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. / 06.2019 / PubMed / Full text
  • Quantum Modeling: A Bridge between the Pumping and Signaling Functions of Na/K-ATPase. / 09.08.2018 / PubMed / Full text
  • Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer. / 30.03.2018 / PubMed / Full text
  • Withanolide A extends the lifespan in human EGFR-driven cancerous Caenorhabditis elegans. / 04.2018 / PubMed / Full text
  • 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Nongenomic effects via the mineralocorticoid receptor. / 07.2017 / PubMed / Full text
  • Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review. / 22.11.2016 / PubMed / Full text
  • Low-frequency [i]KRAS[/i] mutations are prevalent in lung adenocarcinomas. / 03.2015 / PubMed / Full text
  • Association of Polymorphisms in Connective Tissue Growth Factor and Epidermal Growth Factor Receptor Genes With Human Longevity. / 01.08.2017 / PubMed / Full text
  • sPLA2 -IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation. / 09.2016 / PubMed / Full text
  • Mechanisms of skin aging induced by EGFR inhibitors. / 10.2016 / PubMed / Full text
  • Prolactin, EGFR, vimentin and α-actin profiles in elderly rat prostate subjected to steroid hormonal imbalance. / 06.2016 / PubMed / Full text
  • Loss of Maspardin Attenuates the Growth and Maturation of Mouse Cortical Neurons. / 2016 / PubMed / Full text
  • Expression profile analysis of new candidate genes for the therapy of primary osteoporosis. / 2016 / PubMed
  • Selective coexpression of VEGF receptor 2 in EGFRvIII-positive glioblastoma cells prevents cellular senescence and contributes to their aggressive nature. / 05.2016 / PubMed / Full text
  • Bradykinin inhibits oxidative stress-induced senescence of endothelial progenitor cells through the B2R/AKT/RB and B2R/EGFR/RB signal pathways. / 22.09.2015 / PubMed / Full text
  • First-line gefitinib treatment in elderly patients (aged ≥75 years) with non-small cell lung cancer harboring EGFR mutations. / 10.2015 / PubMed / Full text
  • Increased centrosome amplification in aged stem cells of the Drosophila midgut. / 25.07.2014 / PubMed / Full text
  • Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. / 07.05.2014 / PubMed / Full text
  • Thiamin concentration in geriatric hospitalized patients using frusemide. / 2014 / PubMed / Full text
  • 4-Hydroxynonenal impairs transforming growth factor-β1-induced elastin synthesis via epidermal growth factor receptor activation in human and murine fibroblasts. / 06.2014 / PubMed / Full text

LBP[править]

  • Lipopolysaccharide binding protein is associated with CVD risk in older adults. / 08.09.2020 / PubMed / Full text
  • Aging-related liver degeneration is associated with increased bacterial endotoxin and lipopolysaccharide binding protein levels. / 01.04.2020 / PubMed / Full text
  • Biomarkers of leaky gut are related to inflammation and reduced physical function in older adults with cardiometabolic disease and mobility limitations. / 12.2019 / PubMed / Full text
  • Needle-shaped amyloid deposition in rat mammary gland: evidence of a novel amyloid fibril protein. / 03.2020 / PubMed / Full text
  • Effects of Lycium barbarum Polysaccharides on Health and Aging of [i]C. elegans[/i] Depend on [i]daf-12/daf-16[/i]. / 2019 / PubMed / Full text
  • Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8. / 10.07.2019 / PubMed / Full text
  • Lycium barbarum polysaccharides extend the mean lifespan of Drosophila melanogaster. / 17.07.2019 / PubMed / Full text
  • Height loss but not body composition is related to low back pain in community-dwelling elderlies: Shimane CoHRE study. / 10.05.2019 / PubMed / Full text
  • Aging of mouse intervertebral disc and association with back pain. / 06.2019 / PubMed / Full text
  • A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats. / 19.03.2019 / PubMed / Full text
  • Chen-Style Tai Chi for Individuals (Aged 50 Years Old or Above) with Chronic Non-Specific Low Back Pain: A Randomized Controlled Trial. / 12.02.2019 / PubMed / Full text
  • Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity. / 11.03.2019 / PubMed / Full text
  • Factors associated with lumbar disc high-intensity zone (HIZ) on T2-weighted magnetic resonance image: a retrospective study of 3185 discs in 637 patients. / 04.12.2018 / PubMed / Full text
  • Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration [i]in vivo[/i]. / 2018 / PubMed / Full text
  • Use of trunk muscle training and neuromuscular electrical stimulation to reduce pain and disability in an older adult with chronic low back pain: A case report. / 08.2019 / PubMed / Full text
  • Endotoxemia is modulated by quantity and quality of dietary fat in older adults. / 08.2018 / PubMed / Full text
  • Correlates of a Recent History of Disabling Low Back Pain in Community-dwelling Older Persons: The Pain in the Elderly (PAINEL) Study. / 06.2018 / PubMed / Full text
  • The Effectiveness and Safety of Manual Therapy on Pain and Disability in Older Persons With Chronic Low Back Pain: A Systematic Review. / 09.2017 / PubMed / Full text
  • De-educate to re-educate: aging and low back pain. / 12.2017 / PubMed / Full text
  • Activity of Erector Spinae During Trunk Forward Bending and Backward Return: The Effects of Age. / 06.2017 / PubMed / Full text
  • Global Cysteine-Reactivity Profiling during Impaired Insulin/IGF-1 Signaling in C. elegans Identifies Uncharacterized Mediators of Longevity. / 18.08.2016 / PubMed / Full text
  • Age- and brain region-dependent α-synuclein oligomerization is attributed to alterations in intrinsic enzymes regulating α-synuclein phosphorylation in aging monkey brains. / 23.02.2016 / PubMed / Full text
  • Association of Lipopolysaccharide-Binding Protein With Aging-Related Adiposity Change and Prediabetes Among African Ancestry Men. / 03.2016 / PubMed / Full text
  • Age-related differences in trunk intrinsic stiffness. / 11.04.2016 / PubMed / Full text
  • Probiotics Reduce Inflammation in Antiretroviral Treated, HIV-Infected Individuals: Results of the "Probio-HIV" Clinical Trial. / 2015 / PubMed / Full text
  • The effects of age and gender on the lumbopelvic rhythm in the sagittal plane in 309 subjects. / 18.09.2015 / PubMed / Full text
  • Does physical activity moderate the relationship between depression symptomatology and low back pain? Cohort and co-twin control analyses nested in the longitudinal study of aging Danish twins (LSADT). / 04.2016 / PubMed / Full text
  • Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans. / 02.01.2015 / PubMed / Full text
  • Comparative study of human age estimation with or without preclassification of gender and facial expression. / 2014 / PubMed / Full text

LPA[править]

  • Ginseng gintonin, aging societies, and geriatric brain diseases. / 03.2021 / PubMed / Full text
  • Late-life related subtypes of depression - a data-driven approach on cognitive domains and physical frailty. / 22.05.2020 / PubMed / Full text
  • Does sedentary time increase in older adults in the days following participation in intense exercise? / 12.2020 / PubMed / Full text
  • Association of Long-term Exposure to Elevated Lipoprotein(a) Levels With Parental Life Span, Chronic Disease-Free Survival, and Mortality Risk: A Mendelian Randomization Analysis. / 05.02.2020 / PubMed / Full text
  • Elevated Autotaxin and LPA Levels During Chronic Viral Hepatitis and Hepatocellular Carcinoma Associate with Systemic Immune Activation. / 25.11.2019 / PubMed / Full text
  • Lysophosphatidic acid receptor LPA prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome. / 01.2020 / PubMed / Full text
  • Associations of Sedentary and Physically-Active Behaviors With Cognitive-Function Decline in Community-Dwelling Older Adults: Compositional Data Analysis From the NEIGE Study. / 05.11.2020 / PubMed / Full text
  • Validation and comparison of two automated methods for quantifying brain white matter hyperintensities of presumed vascular origin. / 02.2020 / PubMed / Full text
  • The Sedentary Time and Physical Activity Levels on Physical Fitness in the Elderly: A Comparative Cross Sectional Study. / 01.10.2019 / PubMed / Full text
  • Light-Intensity Physical Activity in a Large Prospective Cohort of Older US Adults: A 21-Year Follow-Up of Mortality. / 2020 / PubMed / Full text
  • The Impact of Movement Behaviors on Bone Health in Elderly with Adequate Nutritional Status: Compositional Data Analysis Depending on the Frailty Status. / 09.03.2019 / PubMed / Full text
  • Compositional Influence of Movement Behaviors on Bone Health during Aging. / 08.2019 / PubMed / Full text
  • Duration-Response of Light-Intensity Physical Activity and Glucose Dynamics in Older Adults. / 01.01.2019 / PubMed / Full text
  • Accelerometer-Measured Physical Activity and Sedentary Behavior: A Cross-Sectional Study of Brazilian Older Adults. / 01.11.2018 / PubMed / Full text
  • The Association Between Physical Activity, Including Physical Activity Intensity, and Fear of Falling Differs by Fear Severity in Older Adults Living in the Community. / 16.04.2020 / PubMed / Full text
  • Gintonin Attenuates D-Galactose-Induced Hippocampal Senescence by Improving Long-Term Hippocampal Potentiation, Neurogenesis, and Cognitive Functions. / 2018 / PubMed / Full text
  • Associations of distinct levels of physical activity with mobility in independent healthy older women. / 09.2018 / PubMed / Full text
  • Reallocating Accelerometer-Assessed Sedentary Time to Light or Moderate- to Vigorous-Intensity Physical Activity Reduces Frailty Levels in Older Adults: An Isotemporal Substitution Approach in the TSHA Study. / 02.2018 / PubMed / Full text
  • Lean psoas area does not correlate with clinical outcomes in moderately to severely injured older people. / 03.2018 / PubMed / Full text
  • Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. / 13.10.2017 / PubMed / Full text
  • Stress, Depression, Resilience and Ageing: A Role for the LPA-LPA1 Pathway. / 05.03.2018 / PubMed / Full text
  • A New Anti-Aging Lysophosphatidic Acid from Arabidopsis thaliana. / 2017 / PubMed / Full text
  • Short-duration increases in intraluminal pressure improve vasoconstrictor responses in aged skeletal muscle feed arteries. / 05.2016 / PubMed / Full text
  • Hearing loss and cognition in the Busselton Baby Boomer cohort: An epidemiological study. / 10.2016 / PubMed / Full text
  • The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life. / 2015 / PubMed / Full text
  • Cognitive function in midlife and beyond: physical and cognitive activity related to episodic memory and executive functions. / 2014 / PubMed / Full text
  • Effect of light and vigorous physical activity on balance and gait of older adults. / 11-12.2014 / PubMed / Full text
  • Inverse effects of midlife occupational and leisure time physical activity on mobility limitation in old age--a 28-year prospective follow-up study. / 05.2014 / PubMed / Full text

NPY[править]

  • Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells. / 22.05.2020 / PubMed / Full text
  • Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice. / 03.2020 / PubMed / Full text
  • Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner. / 21.03.2019 / PubMed / Full text
  • β-Alanine supplementation reduces anxiety and increases neurotrophin expression in both young and older rats. / 02.2019 / PubMed / Full text
  • Age-related central regulation of orexin and NPY in the short-lived African killifish Nothobranchius furzeri. / 15.05.2019 / PubMed / Full text
  • Chronic treatment with tributyltin induces sexually dimorphic alterations in the hypothalamic POMC system of adult mice. / 12.2018 / PubMed / Full text
  • Expression of CGRP neurotransmitter and vascular genesis marker mRNA is age-dependent in superior cervical ganglia of senescence-accelerated prone mice. / 18.01.2018 / PubMed / Full text
  • Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway. / 01.2018 / PubMed / Full text
  • Bioactive growth hormone in older men and women: It's relationship to immune markers and healthspan. / 06.2017 / PubMed / Full text
  • Retinal, NPY- and 5ht- inputs to the aged suprachiasmatic nucleus in common marmosets (Callithrix jacchus). / 08.2017 / PubMed / Full text
  • Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis. / 01.03.2017 / PubMed / Full text
  • Neuropeptide Y resists excess loss of fat by lipolysis in calorie-restricted mice: a trait potential for the life-extending effect of calorie restriction. / 04.2017 / PubMed / Full text
  • Nerve growth factor-induced plasticity in medial prefrontal cortex interneurons of aged Wistar rats. / 01.12.2016 / PubMed / Full text
  • Age Impaired endothelium-dependent vasodilation is improved by resveratrol in rat mesenteric arteries. / 31.03.2016 / PubMed / Full text
  • Age-related changes in neurochemical components and retinal projections of rat intergeniculate leaflet. / 02.2016 / PubMed / Full text
  • Short photoperiod condition increases susceptibility to stress in adolescent male rats. / 01.03.2016 / PubMed / Full text
  • Neuropeptide Y: An Anti-Aging Player? / 11.2015 / PubMed / Full text
  • Influence of Aging and Gender Differences on Feeding Behavior and Ghrelin-Related Factors during Social Isolation in Mice. / 2015 / PubMed / Full text
  • Reduction in NPY-positive neurons and dysregulation of excitability in young senescence-accelerated mouse prone 8 (SAMP8) hippocampus precede the onset of cognitive impairment. / 10.2015 / PubMed / Full text
  • Age effects on the nucleus of the lateral olfactory tract of the rat. / 01.03.2016 / PubMed / Full text
  • NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging? / 2015 / PubMed / Full text
  • Analysis of gene expression during aging of CGNs in culture: implication of SLIT2 and NPY in senescence. / 06.2015 / PubMed / Full text
  • Neuropeptide Y stimulates autophagy in hypothalamic neurons. / 31.03.2015 / PubMed / Full text
  • Effect of IP3R3 and NPY on age-related declines in olfactory stem cell proliferation. / 02.2015 / PubMed / Full text
  • Old-onset caloric restriction effects on neuropeptide Y- and somatostatin-containing neurons and on cholinergic varicosities in the rat hippocampal formation. / 2014 / PubMed / Full text
  • Orally administered δ opioid agonist peptide rubiscolin-6 stimulates food intake in aged mice with ghrelin resistance. / 10.2014 / PubMed / Full text
  • Ghrelin receptor regulates appetite and satiety during aging in mice by regulating meal frequency and portion size but not total food intake. / 09.2014 / PubMed / Full text
  • Distribution of peptidergic populations in the human dentate gyrus (somatostatin [SOM-28, SOM-12] and neuropeptide Y [[[NPY]]]) during postnatal development. / 10.2014 / PubMed / Full text

ATF4[править]

  • Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78-Loaded Extracellular Vesicles. / 10.12.2020 / PubMed / Full text
  • Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells. / 01.2020 / PubMed / Full text
  • Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis. / 06.2019 / PubMed / Full text
  • Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
  • Effects of a resistance-training programme on endoplasmic reticulum unfolded protein response and mitochondrial functions in PBMCs from elderly subjects. / 08.2019 / PubMed / Full text
  • [Protective effect of Wuzi Yanzong recipe on testicular germ cell apoptosis in natural ageing rats through endoplasmic reticulum stress]. / 10.2018 / PubMed / Full text
  • Protective effect of Wuzi Yanzong recipe on testicular dysfunction through inhibition of germ cell apoptosis in ageing rats via endoplasmic reticulum stress. / 03.2019 / PubMed / Full text
  • Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration. / 01.2019 / PubMed / Full text
  • Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text
  • De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver. / 05.2018 / PubMed / Full text
  • Resveratrol modulates response against acute inflammatory stimuli in aged mouse brain. / 02.2018 / PubMed / Full text
  • Integrated stress response stimulates FGF21 expression: Systemic enhancer of longevity. / 12.2017 / PubMed / Full text
  • Role of ATF4 in skeletal muscle atrophy. / 05.2017 / PubMed / Full text
  • 4E-BP is a target of the GCN2-ATF4 pathway during Drosophila development and aging. / 02.01.2017 / PubMed / Full text
  • Diaminodiphenyl sulfone-induced parkin ameliorates age-dependent dopaminergic neuronal loss. / 05.2016 / PubMed / Full text
  • Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation. / 13.05.2016 / PubMed / Full text
  • Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice. / 15.01.2016 / PubMed / Full text
  • Unfolded protein response is activated in aged retinas. / 16.11.2015 / PubMed / Full text
  • Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy. / 16.10.2015 / PubMed / Full text
  • Effect of mitochondrial stress on systemic metabolism. / 09.2015 / PubMed / Full text
  • Senescence may mediate conversion of tau phosphorylation-induced apoptotic escape to neurodegeneration. / 08.2015 / PubMed / Full text
  • Impact of ER stress-regulated ATF4/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy. / 15.04.2015 / PubMed / Full text
  • ATF4 activity: a common feature shared by many kinds of slow-aging mice. / 12.2014 / PubMed / Full text
  • The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout. / 15.09.2014 / PubMed / Full text
  • Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21. / 10.2014 / PubMed / Full text
  • The first international mini-symposium on methionine restriction and lifespan. / 2014 / PubMed / Full text
  • Elevated ATF4 function in fibroblasts and liver of slow-aging mutant mice. / 03.2015 / PubMed / Full text

DDT[править]

  • Prognostic Value of a Test of Central Auditory Function in Conversion from Mild Cognitive Impairment to Dementia. / 2020 / PubMed / Full text
  • Uptake kinetics of four hydrophobic organic pollutants in the earthworm Eisenia andrei in aged laboratory-contaminated natural soils. / 01.04.2020 / PubMed / Full text
  • Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish. / 03-04.2020 / PubMed / Full text
  • Second generation effects of larval metal pollutant exposure on reproduction, longevity and insecticide tolerance in the major malaria vector Anopheles arabiensis (Diptera: Culicidae). / 07.01.2020 / PubMed / Full text
  • Protective effect of Pedro-Ximénez must against p,p'-DDE-induced liver damages in aged Mus spretus mice. / 02.2020 / PubMed / Full text
  • Low-dose endosulfan inhibits proliferation and induces senescence and pro-inflammatory cytokine production in human lymphocytes, preferentially impacting cytotoxic cells. / 12.2019 / PubMed / Full text
  • DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy. / 22.08.2019 / PubMed / Full text
  • The contribution of gut bacteria to insecticide resistance and the life histories of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). / 24.06.2019 / PubMed / Full text
  • Exposure to the insecticide-treated bednet PermaNet 2.0 reduces the longevity of the wild African malaria vector Anopheles funestus but GSTe2-resistant mosquitoes live longer. / 2019 / PubMed / Full text
  • The occurrence and dynamics of polychlorinated hydrocarbons in roe deer ([i]Capreolus capreolus[/i]) in South-western Slovakia. / 2019 / PubMed / Full text
  • Insecticide resistance status of three vectors of Japanese encephalitis in east central India. / 06.2019 / PubMed / Full text
  • Effect of aging on bioaccessibility of DDTs and PCBs in marine sediment. / 02.2019 / PubMed / Full text
  • The effect of commercial herbicide exposure on the life history and insecticide resistance phenotypes of the major malaria vector Anopheles arabiensis (Diptera: culicidae). / 12.2018 / PubMed / Full text
  • Is Chronic Exposure to Low-Dose Organochlorine Pesticides a New Risk Factor of T-cell Immunosenescence? / 10.2018 / PubMed / Full text
  • The influence of age on insecticide susceptibility of Anopheles arabiensis during dry and rainy seasons in rice irrigation schemes of Northern Tanzania. / 11.09.2017 / PubMed / Full text
  • DNA damage tolerance in hematopoietic stem and progenitor cells in mice. / 15.08.2017 / PubMed / Full text
  • The effects of ingestion of hormonal host factors on the longevity and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). / 2017 / PubMed / Full text
  • Bioavailability of five hydrophobic organic compounds to earthworms from sterile and non-sterile artificial soils. / 07.2017 / PubMed / Full text
  • The effect of elevated temperatures on the life history and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae). / 14.02.2017 / PubMed / Full text
  • Dichotic Digits Test Performance Across the Ages: Results From Two Large Epidemiologic Cohort Studies. / 05-06.2017 / PubMed / Full text
  • The Role of Oxidative Stress in the Longevity and Insecticide Resistance Phenotype of the Major Malaria Vectors Anopheles arabiensis and Anopheles funestus. / 2016 / PubMed / Full text
  • Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila. / 02.02.2016 / PubMed / Full text
  • Influence of feeding and earthworm density on compound bioaccumulation in earthworms Eisenia andrei. / 12.2015 / PubMed / Full text
  • Greater cognitive decline with aging among elders with high serum concentrations of organochlorine pesticides. / 2015 / PubMed / Full text
  • The effect of multiple blood-feeding on the longevity and insecticide resistant phenotype in the major malaria vector Anopheles arabiensis (Diptera: Culicidae). / 23.08.2014 / PubMed / Full text
  • The role of canine distemper virus and persistent organic pollutants in mortality patterns of Caspian seals (Pusa caspica). / 2014 / PubMed / Full text
  • Solid phase microextraction of organic pollutants from natural and artificial soils and comparison with bioaccumulation in earthworms. / 02.2014 / PubMed / Full text

FOXO1[править]

  • l-Theanine attenuates liver aging by inhibiting advanced glycation end products in d-galactose-induced rats and reversing an imbalance of oxidative stress and inflammation. / 03.2020 / PubMed / Full text
  • Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation. / 2018 / PubMed / Full text
  • Functional pathways regulated by microRNA networks in CD8 T-cell aging. / 02.2019 / PubMed / Full text
  • Introduction to FOXO Biology. / 2019 / PubMed / Full text
  • Antioxidant modifications induced by the new metformin derivative HL156A regulate metabolic reprogramming in SAMP1/kl (-/-) mice. / 16.09.2018 / PubMed / Full text
  • Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls. / 10.2018 / PubMed / Full text
  • FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence. / 01.2019 / PubMed / Full text
  • Autophagy mediators (FOXO1, SESN3 and TSC2) in Lewy body disease and aging. / 25.09.2018 / PubMed / Full text
  • FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration. / 10.2018 / PubMed / Full text
  • Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation. / 05.2018 / PubMed / Full text
  • HGF and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the SIRT1/FOXO1 Signaling Pathway. / 2018 / PubMed / Full text
  • Role of Forkhead Box O (FOXO) transcription factor in aging and diseases. / 30.03.2018 / PubMed / Full text
  • FOXO in Neural Cells and Diseases of the Nervous System. / 2018 / PubMed / Full text
  • Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium. / 11.12.2017 / PubMed / Full text
  • FOXO Transcriptional Factors and Long-Term Living. / 2017 / PubMed / Full text
  • Aquatide Activation of SIRT1 Reduces Cellular Senescence through a SIRT1-FOXO1-Autophagy Axis. / 01.09.2017 / PubMed / Full text
  • The protein kinase MBK-1 contributes to lifespan extension in [i]daf-2[/i] mutant and germline-deficient [i]Caenorhabditis elegans[/i]. / 25.05.2017 / PubMed / Full text
  • Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-FOXO1 pathway. / 2017 / PubMed / Full text
  • Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment. / 30.05.2017 / PubMed / Full text
  • Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration. / 12.2017 / PubMed / Full text
  • Oxidative Stress-Induced miR-200c Disrupts the Regulatory Loop Among SIRT1, FOXO1, and eNOS. / 20.08.2017 / PubMed / Full text
  • miR-96, miR-145 and miR-9 expression increases, and IGF-1R and FOXO1 expression decreases in peripheral blood mononuclear cells of aging humans. / 30.11.2016 / PubMed / Full text
  • Cone Viability Is Affected by Disruption of Melatonin Receptors Signaling. / 01.01.2016 / PubMed / Full text
  • Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility. / 04.2016 / PubMed / Full text
  • Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. / 04.2016 / PubMed / Full text
  • Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase. / 01.2016 / PubMed / Full text
  • Endogenous ROS levels are increased in replicative senescence in human bone marrow mesenchymal stromal cells. / 15.05.2015 / PubMed / Full text

HMGB1[править]

  • Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction. / 02.12.2019 / PubMed / Full text
  • Targeting HMGB1 by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells. / 14.07.2019 / PubMed / Full text
  • HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration. / 07.07.2019 / PubMed / Full text
  • Dual faced HMGB1 plays multiple roles in cardiomyocyte senescence and cardiac inflammatory injury. / 06.2019 / PubMed / Full text
  • Neuroprotective Effect of Dioscin on the Aging Brain. / 30.03.2019 / PubMed / Full text
  • Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging. / 23.03.2019 / PubMed / Full text
  • Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis. / 30.04.2019 / PubMed / Full text
  • Serum and nutrient deprivation increase autophagic flux in intervertebral disc annulus fibrosus cells: an in vitro experimental study. / 05.2019 / PubMed / Full text
  • Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. / 01.05.2019 / PubMed / Full text
  • Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
  • Repeated abortion in adulthood induces cognition impairment in aged mice. / 30.07.2018 / PubMed / Full text
  • Loss of DNA polymerase β induces cellular senescence. / 08.2018 / PubMed / Full text
  • Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats. / 06.03.2018 / PubMed / Full text
  • Intestinal Permeability Biomarker Zonulin is Elevated in Healthy Aging. / 01.09.2017 / PubMed / Full text
  • Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging. / 06.2017 / PubMed / Full text
  • Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women. / 08.2017 / PubMed / Full text
  • Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats. / 2016 / PubMed / Full text
  • The Alarmin HMGB1 Mediates Age-Induced Neuroinflammatory Priming. / 27.07.2016 / PubMed / Full text
  • Human fetal membranes at term: Dead tissue or signalers of parturition? / 08.2016 / PubMed / Full text
  • Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice. / 2016 / PubMed / Full text
  • DAMPs and influenza virus infection in ageing. / 11.2015 / PubMed / Full text
  • Decreased serum level of HMGB1 and MyD88 during human aging progress in healthy individuals. / 04.2016 / PubMed / Full text
  • [Peptides and [[CCL11]] and HMGB1 as molecular markers of aging: literature review and own data]. / 2014 / PubMed
  • HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice. / 01.2015 / PubMed / Full text
  • Secondhand smoke exposure-induced nucleocytoplasmic shuttling of HMGB1 in a rat premature skin aging model. / 02.01.2015 / PubMed / Full text
  • Changes in the expression of the Toll-like receptor system in the aging rat kidneys. / 2014 / PubMed / Full text
  • Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating CD200-CD200R interaction involve the cannabinoid system. / 2014 / PubMed / Full text

KL[править]

  • The goddess who spins the thread of life: Klotho, psychiatric stress, and accelerated aging. / 08.2019 / PubMed / Full text
  • [i]KLOTHO[/i] heterozygosity attenuates [i]APOE4[/i]-related amyloid burden in preclinical AD. / 16.04.2019 / PubMed / Full text
  • Utilizing Atlas-Based Modeling to Predict Knee Joint Cartilage Degeneration: Data from the Osteoarthritis Initiative. / 03.2019 / PubMed / Full text
  • Impaired proteostasis in senescent vascular endothelial cells: a perspective on estrogen and oxidative stress in the aging vasculature. / 01.02.2019 / PubMed / Full text
  • Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis. / 04.2019 / PubMed / Full text
  • Klotho at the Edge of Alzheimer's Disease and Senile Depression. / 03.2019 / PubMed / Full text
  • Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. / 10.2018 / PubMed / Full text
  • G-395A polymorphism in the promoter region of the KLOTHO gene associates with frailty among the oldest-old. / 30.04.2018 / PubMed / Full text
  • Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling. / 2017 / PubMed / Full text
  • Changes in expression of klotho affect physiological processes, diseases, and cancer. / 01.2018 / PubMed / Full text
  • Anti-aging factor, serum alpha-Klotho, as a marker of acute physiological stress, and a predictor of ICU mortality, in patients with septic shock. / 04.2018 / PubMed / Full text
  • Secreted αKlotho isoform protects against age-dependent memory deficits. / 09.2018 / PubMed / Full text
  • Induction of anti-aging gene klotho with a small chemical compound that demethylates CpG islands. / 18.07.2017 / PubMed / Full text
  • Longevity Klotho gene polymorphism and the risk of dementia in older men. / 07.2017 / PubMed / Full text
  • Klotho, APOEε4, cognitive ability, brain size, atrophy, and survival: a study in the Aberdeen Birth Cohort of 1936. / 07.2017 / PubMed / Full text
  • The relevance of α-KLOTHO to the central nervous system: Some key questions. / 07.2017 / PubMed / Full text
  • Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging. / 04.2017 / PubMed / Full text
  • Activation of SIRT1 Attenuates Klotho Deficiency-Induced Arterial Stiffness and Hypertension by Enhancing AMP-Activated Protein Kinase Activity. / 11.2016 / PubMed / Full text
  • The FGF23/KLOTHO Regulatory Network and Its Roles in Human Disorders. / 2016 / PubMed / Full text
  • Antiaging Gene Klotho Deficiency Promoted High-Fat Diet-Induced Arterial Stiffening via Inactivation of AMP-Activated Protein Kinase. / 03.2016 / PubMed / Full text
  • KL-optimal experimental design for discriminating between two growth models applied to a beef farm. / 02.2016 / PubMed / Full text
  • Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease Progression. / 2015 / PubMed / Full text
  • Genetic Variants in KLOTHO Associate With Cognitive Function in the Oldest Old Group. / 09.2016 / PubMed / Full text
  • N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models. / 2015 / PubMed / Full text
  • Senescence-inducible LEC2 enhances triacylglycerol accumulation in leaves without negatively affecting plant growth. / 12.2015 / PubMed / Full text
  • Molecular basis of Klotho: from gene to function in aging. / 04.2015 / PubMed / Full text
  • Life extension factor klotho enhances cognition. / 22.05.2014 / PubMed / Full text

TFAM[править]

  • Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. / 01.10.2019 / PubMed / Full text
  • Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. / 08.07.2019 / PubMed / Full text
  • Differences in Liver TFAM Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats. / 27.05.2019 / PubMed / Full text
  • Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. / 2019 / PubMed / Full text
  • [A study on alterations in mitochondrial biological characteristics during cellular senescence of human embryonic lung fibroblasts]. / 06.03.2019 / PubMed / Full text
  • Changes in Stemness Properties, Differentiation Potential, Oxidative Stress, Senescence and Mitochondrial Function in Wharton's Jelly Stem Cells of Umbilical Cords of Mothers with Gestational Diabetes Mellitus. / 06.2019 / PubMed / Full text
  • Cycling CD4 T cells in HIV-infected immune nonresponders have mitochondrial dysfunction. / 01.11.2018 / PubMed / Full text
  • Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart. / 20.08.2018 / PubMed / Full text
  • Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice. / 08.2018 / PubMed / Full text
  • Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1α pathway. / 02.2018 / PubMed / Full text
  • Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. / 02.2018 / PubMed / Full text
  • Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats. / 11.2017 / PubMed / Full text
  • Effect of lifelong football training on the expression of muscle molecular markers involved in healthy longevity. / 04.2017 / PubMed / Full text
  • Regulation of mitochondrial gene expression, the epigenetic enigma. / 01.03.2017 / PubMed / Full text
  • Poor embryo development in post-ovulatory in vivo-aged mouse oocytes is associated with mitochondrial dysfunction, but mitochondrial transfer from somatic cells is not sufficient for rejuvenation. / 10.2016 / PubMed / Full text
  • Disentangling the effect of dietary restriction on mitochondrial function using recombinant inbred mice. / 05.11.2017 / PubMed / Full text
  • "What makes some rats live so long?" The mitochondrial contribution to longevity through balance of mitochondrial dynamics and mtDNA content. / 01.12.2016 / PubMed / Full text
  • Response of BAX, Bcl-2 Proteins, and SIRT1/PGC-1α mRNA Expression to 8-Week Treadmill Running in the Aging Rat Skeletal Muscle. / 2016 / PubMed / Full text
  • Methylene blue improves sensorimotor phenotype and decreases anxiety in parallel with activating brain mitochondria biogenesis in mid-age mice. / 12.2016 / PubMed / Full text
  • HIF-1 regulates insect lifespan extension by inhibiting c-Myc-TFAM signaling and mitochondrial biogenesis. / 11.2016 / PubMed / Full text
  • Resistance exercise training and in vitro skeletal muscle oxidative capacity in older adults. / 07.2016 / PubMed / Full text
  • Mitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disorders. / 11.2016 / PubMed / Full text
  • Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of INS-1 cells through Pim-1. / 2016 / PubMed
  • Regulation of mitochondrial biogenesis through TFAM-mitochondrial DNA interactions: Useful insights from aging and calorie restriction studies. / 11.2015 / PubMed / Full text
  • Dietary Tocotrienol/γ-Cyclodextrin Complex Increases Mitochondrial Membrane Potential and ATP Concentrations in the Brains of Aged Mice. / 2015 / PubMed / Full text
  • A comparison among the tissue-specific effects of aging and calorie restriction on TFAM amount and TFAM-binding activity to mtDNA in rat. / 07.2014 / PubMed / Full text
  • Partial reversal of skeletal muscle aging by restoration of normal NAD⁺ levels. / 02.2014 / PubMed / Full text

ASL[править]

  • Increased blood-brain barrier permeability to water in the aging brain detected using noninvasive multi-TE ASL MRI. / 01.2021 / PubMed / Full text
  • Quantitative Cerebrovascular Reactivity in Normal Aging: Comparison Between Phase-Contrast and Arterial Spin Labeling MRI. / 2020 / PubMed / Full text
  • Correcting Task fMRI Signals for Variability in Baseline CBF Improves BOLD-Behavior Relationships: A Feasibility Study in an Aging Model. / 2020 / PubMed / Full text
  • Cerebral Blood Flow in Community-Based Older Twins Is Moderately Heritable: An Arterial Spin Labeling Perfusion Imaging Study. / 2019 / PubMed / Full text
  • A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure. / 15.08.2019 / PubMed / Full text
  • Cortical cerebral blood flow in ageing: effects of haematocrit, sex, ethnicity and diabetes. / 10.2019 / PubMed / Full text
  • Exercise-stimulated arterial transit time in calf muscles measured by dynamic contrast-enhanced magnetic resonance imaging. / 01.2019 / PubMed / Full text
  • Impact of Coffee, Wine, and Chocolate Consumption on Cognitive Outcome and MRI Parameters in Old Age. / 01.10.2018 / PubMed / Full text
  • Potential Role of OERP as Early Marker of Mild Cognitive Impairment. / 2018 / PubMed / Full text
  • Reduced Regional Cerebral Blood Flow Relates to Poorer Cognition in Older Adults With Type 2 Diabetes. / 2018 / PubMed / Full text
  • The Age-Related Perfusion Pattern Measured With Arterial Spin Labeling MRI in Healthy Subjects. / 2018 / PubMed / Full text
  • Resilience and amygdala function in older healthy and depressed adults. / 09.2018 / PubMed / Full text
  • Does Aerobic Exercise Influence Intrinsic Brain Activity? An Aerobic Exercise Intervention among Healthy Old Adults. / 2017 / PubMed / Full text
  • Cerebral blood flow and vasoreactivity in aging: an arterial spin labeling study. / 23.03.2017 / PubMed / Full text
  • Cerebral blood flow measured by arterial spin labeling MRI at resting state in normal aging and Alzheimer's disease. / 01.2017 / PubMed / Full text
  • Cerebral blood flow MRI in the nondemented elderly is not predictive of post-operative delirium but is correlated with cognitive performance. / 04.2017 / PubMed / Full text
  • Improving drug retention in liposomes by aging with the aid of glucose. / 30.05.2016 / PubMed / Full text
  • The Utility of Cerebral Blood Flow as a Biomarker of Preclinical Alzheimer's Disease. / 03.2016 / PubMed / Full text
  • Long-term effect of orthokeratology on the anterior segment length. / 08.2016 / PubMed / Full text
  • Comparison of long-labeled pseudo-continuous arterial spin labeling (ASL) features between young and elderly adults: special reference to parameter selection. / 01.2017 / PubMed / Full text
  • Assessing intracranial vascular compliance using dynamic arterial spin labeling. / 01.01.2016 / PubMed / Full text
  • Lens Position and Age: The Central India Eye and Medical Study. / 08.2015 / PubMed / Full text
  • Age-related changes in brain hemodynamics; A calibrated MRI study. / 10.2015 / PubMed / Full text
  • Characterizing the white matter hyperintensity penumbra with cerebral blood flow measures. / 2015 / PubMed / Full text
  • Tissue specific arterial spin labeling fMRI: a superior method for imaging cerebral blood flow in aging and disease. / 2014 / PubMed / Full text
  • Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. / 02.2014 / PubMed / Full text

BRCA1[править]

  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
  • PML nuclear bodies are recruited to persistent DNA damage lesions in an RNF168-53BP1 dependent manner and contribute to DNA repair. / 06.2019 / PubMed / Full text
  • Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. / 2019 / PubMed / Full text
  • Klotho gene polymorphisms are associated with healthy aging and longevity: Evidence from a meta-analysis. / 03.2019 / PubMed / Full text
  • High expression of the breast cancer susceptibility gene BRCA1 in long-lived termite kings. / 11.10.2018 / PubMed / Full text
  • The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. / 2018 / PubMed / Full text
  • Cost effectiveness of population based BRCA1 founder mutation testing in Sephardi Jewish women. / 04.2018 / PubMed / Full text
  • Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions. / 04.01.2018 / PubMed / Full text
  • Faulty BRCA1, BRCA2 genes: how poor is the prognosis? / 10.2017 / PubMed / Full text
  • Ovarian Aging in Women With BRCA Germline Mutations. / 01.10.2017 / PubMed / Full text
  • The expected benefit of preventive mastectomy on breast cancer incidence and mortality in BRCA mutation carriers, by age at mastectomy. / 01.2018 / PubMed / Full text
  • A BRCA1-Dependent DNA Damage Response in the Regenerating Adult Peripheral Nerve Milieu. / 05.2018 / PubMed / Full text
  • The Histone Variant MacroH2A1 Is a BRCA1 Ubiquitin Ligase Substrate. / 30.05.2017 / PubMed / Full text
  • A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer. / 04.2017 / PubMed / Full text
  • Serum AMH levels in healthy women from BRCA1/2 mutated families: are they reduced? / 11.2016 / PubMed / Full text
  • p16INK4a suppresses BRCA1-deficient mammary tumorigenesis. / 20.12.2016 / PubMed / Full text
  • BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries. / 03.04.2017 / PubMed / Full text
  • Women's preferences for contralateral prophylactic mastectomy: An investigation using protection motivation theory. / 05.2016 / PubMed / Full text
  • Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome. / 15.03.2016 / PubMed / Full text
  • Genetic suppression reveals DNA repair-independent antagonism between BRCA1 and COBRA1 in mammary gland development. / 04.03.2016 / PubMed / Full text
  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. / 11.2015 / PubMed / Full text
  • Comparative proteomic analysis of primordial follicles from ovaries of immature and aged rats. / 2015 / PubMed / Full text
  • BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging. / 09.2015 / PubMed / Full text
  • Increased DNA damage and repair deficiency in granulosa cells are associated with ovarian aging in rhesus monkey. / 07.2015 / PubMed / Full text
  • Conservation of pro-longevity genes among mammals. / 03.2015 / PubMed / Full text
  • Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells. / 06.2015 / PubMed / Full text

C5[править]

  • The C5-75 Program: Meeting the Need for Efficient, Pragmatic Frailty Screening and Management in Primary Care. / 23.06.2020 / PubMed / Full text
  • Can a relatively large spinal cord for the dural sac influence severity of paralysis in elderly patients with cervical spinal cord injury caused by minor trauma? / 26.06.2020 / PubMed / Full text
  • Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. / 2018 / PubMed / Full text
  • Longevity of adenovirus vector immunity in mice and its implications for vaccine efficacy. / 29.10.2018 / PubMed / Full text
  • Generating Rasch-based activity of daily living measures from the Spinal Cord Injury Longitudinal Aging Study. / 01.2018 / PubMed / Full text
  • A Large Cohort Study of 18F Fluoro-Deoxy-Glucose Uptake in Normal Spinal Cord: Quantitative Assessment of the Contamination From Adjacent Vertebral Marrow Uptake and Validity of Normalizing the Cord Uptake Against the Lumbar Thecal Sac. / 01.2017 / PubMed / Full text
  • Demographic aspects in cervical vertebral bodies' size and shape (C3-C7): a skeletal study. / 01.2017 / PubMed / Full text
  • Tract-specific and age-related variations of the spinal cord microstructure: a multi-parametric MRI study using diffusion tensor imaging (DTI) and inhomogeneous magnetization transfer (ihMT). / 06.2016 / PubMed / Full text
  • Age-related brain atrophy may be mitigated by internal jugular vein enlargement in male individuals without neurologic disease. / 03.2017 / PubMed / Full text
  • The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis. / 2016 / PubMed / Full text
  • Signal intensity loss of the intervertebral discs in the cervical spine of young patients on fluid sensitive sequences. / 03.2016 / PubMed / Full text
  • Are the standard parameters of cervical spine alignment and range of motion related to age, sex, and cervical disc degeneration? / 09.2015 / PubMed / Full text
  • DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease. / 2015 / PubMed / Full text
  • Permeability and shear modulus of articular cartilage in growing mice. / 02.2016 / PubMed / Full text
  • Acute exercise increases hippocampal TNF-α, Caspase-3 and Caspase-7 expression in healthy young and older mice. / 04.2015 / PubMed
  • Age influences inflammatory responses, hemodynamics, and cardiac proteasome activation during acute lung injury. / 05.2015 / PubMed / Full text
  • Minocycline enhances hippocampal memory, neuroplasticity and synapse-associated proteins in aged C57 BL/6 mice. / 05.2015 / PubMed / Full text
  • Presence of rd8 mutation does not alter the ocular phenotype of late-onset retinal degeneration mouse model. / 2015 / PubMed / Full text
  • Concentration- and age-dependent effects of chronic caffeine on contextual fear conditioning in C57BL/6J mice. / 01.02.2016 / PubMed / Full text
  • Miglitol protects against age-dependent weight gain in mice: A potential role of increased UCP1 content in brown adipose tissue. / 2015 / PubMed / Full text
  • Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. / 06.2015 / PubMed / Full text
  • A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging. / 20.04.2015 / PubMed / Full text
  • Anti-skin ageing activity of napthoquinones from Arnebia nobilis Reichb.f. / 2016 / PubMed / Full text
  • Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture. / 05.2015 / PubMed / Full text
  • Age-associated oxidative modifications of mitochondrial α-subunit of F1 ATP synthase from mouse skeletal muscles. / 2015 / PubMed / Full text
  • Videofluoroscopic Validation of a Translational Murine Model of Presbyphagia. / 06.2015 / PubMed / Full text

COMT[править]

  • The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain. / 05.2020 / PubMed / Full text
  • A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study. / 05.2019 / PubMed / Full text
  • Frontoparietal cortical thickness mediates the effect of COMT Val Met polymorphism on age-associated executive function. / 01.2019 / PubMed / Full text
  • [MELATONIN: THE POSSIBILITY TO ANALYSE THE MARKER OF AGE-RELATED PATHOLOGY IN THE BUCCAL EPITHELIUM AND URINE]. / 2017 / PubMed
  • The Moderating Role of COMT and BDNF Polymorphisms on Transfer Effects Following Multi- and Single-Domain Cognitive Training Among Community-Dwelling Shanghainese Older Adults. / 2018 / PubMed / Full text
  • Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age. / 2018 / PubMed / Full text
  • Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study. / 07.2018 / PubMed / Full text
  • Genetic Biomarkers on Age-Related Cognitive Decline. / 2017 / PubMed / Full text
  • A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers. / 07.2017 / PubMed / Full text
  • Catechol-O-Methyltransferase Genotype and Gait Speed Changes over 10 Years in Older Adults. / 09.2017 / PubMed / Full text
  • [Melatonin as a molecular marker of age-related pathologies]. / 2017 / PubMed
  • Chloroplast overexpression of rice caffeic acid O-methyltransferase increases melatonin production in chloroplasts via the 5-methoxytryptamine pathway in transgenic rice plants. / 08.2017 / PubMed / Full text
  • Age-dependent role of pre- and perinatal factors in interaction with genes on ADHD symptoms across adolescence. / 07.2017 / PubMed / Full text
  • Age differences in arterial and venous extra-cerebral blood flow in healthy adults: contributions of vascular risk factors and genetic variants. / 08.2017 / PubMed / Full text
  • Executive function performance and change in aging is predicted by apolipoprotein E, intensified by catechol-O-methyltransferase and brain-derived neurotrophic factor, and moderated by age and lifestyle. / 04.2017 / PubMed / Full text
  • Age-Dependent Effects of Catechol-O-Methyltransferase (COMT) Gene Val158Met Polymorphism on Language Function in Developing Children. / 01.01.2017 / PubMed / Full text
  • Aging and the genetic road towards the positivity effect in memory. / 09.2016 / PubMed / Full text
  • Older age may offset genetic influence on affect: The COMT polymorphism and affective well-being across the life span. / 05.2016 / PubMed / Full text
  • Differential effect of age on posterior and anterior hippocampal functional connectivity. / 06.2016 / PubMed / Full text
  • Pulse Pressure Magnifies the Effect of COMT Val(158)Met on 15 Years Episodic Memory Trajectories. / 2016 / PubMed / Full text
  • Modulative effects of COMT haplotype on age-related associations with brain morphology. / 06.2016 / PubMed / Full text
  • COMT Val158Met polymorphism is associated with blood pressure and lipid levels in general families of Bama longevous area in China. / 2015 / PubMed / Full text
  • Genetic Basis of the Relationship Between Reproduction and Longevity: A Study on Common Variants of Three Genes in Steroid Hormone Metabolism--CYP17, HSD17B1, and COMT. / 10.2015 / PubMed / Full text
  • Cognitive ability, intraindividual variability, and common genetic variants of catechol-O-methyltransferase and brain-derived neurotrophic factor: a longitudinal study in a population-based sample of older adults. / 06.2014 / PubMed / Full text
  • Healthy aging increases the cognitive effects of two genes that influence extracellular dopamine. / 06.2014 / PubMed / Full text
  • BDNF and COMT polymorphisms have a limited association with episodic memory performance or engagement in complex cognitive activity in healthy older adults. / 04.2014 / PubMed / Full text

LRRK2[править]

  • Accelerated telomere shortening independent of LRRK2 variants in Chinese patients with Parkinson's disease. / 29.10.2020 / PubMed / Full text
  • The effect of LRRK2 loss-of-function variants in humans. / 06.2020 / PubMed / Full text
  • Parkinson's disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging. / 19.02.2020 / PubMed / Full text
  • Autophagy and LRRK2 in the Aging Brain. / 2019 / PubMed / Full text
  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
  • Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA). / 02.2020 / PubMed / Full text
  • A Neuron-Glial Trans-Signaling Cascade Mediates LRRK2-Induced Neurodegeneration. / 12.02.2019 / PubMed / Full text
  • Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein. / 02.2019 / PubMed / Full text
  • G2019S LRRK2 mutation facilitates α-synuclein neuropathology in aged mice. / 12.2018 / PubMed / Full text
  • The Enzymatic Core of the Parkinson's Disease-Associated Protein LRRK2 Impairs Mitochondrial Biogenesis in Aging Yeast. / 2018 / PubMed / Full text
  • Age-related pathology after adenoviral overexpression of the leucine-rich repeat kinase 2 in the mouse striatum. / 06.2018 / PubMed / Full text
  • LRRK2 G2019S Induces Anxiety/Depression-like Behavior before the Onset of Motor Dysfunction with 5-HT Receptor Upregulation in Mice. / 14.02.2018 / PubMed / Full text
  • Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice. / 15.11.2017 / PubMed / Full text
  • Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice. / 20.09.2017 / PubMed / Full text
  • Suppression of neuroinflammation by matrix metalloproteinase-8 inhibitor in aged normal and LRRK2 G2019S Parkinson's disease model mice challenged with lipopolysaccharide. / 18.11.2017 / PubMed / Full text
  • Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. / 02.08.2017 / PubMed / Full text
  • Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice. / 14.03.2017 / PubMed / Full text
  • Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson's disease. / 18.01.2017 / PubMed / Full text
  • LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function. / 01.03.2016 / PubMed / Full text
  • Functional and Morphological Correlates in the Drosophila LRRK2 loss-of-function Model of Parkinson's Disease: Drug Effects of Withania somnifera (Dunal) Administration. / 2016 / PubMed / Full text
  • G2019S LRRK2 and aging confer susceptibility to proteasome inhibitor-induced neurotoxicity in nigrostriatal dopaminergic system. / 12.2015 / PubMed / Full text
  • An early axonopathy in a hLRRK2(R1441G) transgenic model of Parkinson disease. / 10.2015 / PubMed / Full text
  • Mutations in LRRK2 potentiate age-related impairment of autophagic flux. / 11.07.2015 / PubMed / Full text
  • [11C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat. / 08.2015 / PubMed / Full text
  • Changes in actin dynamics and F-actin structure both in synaptoneurosomes of LRRK2(R1441G) mutant mice and in primary human fibroblasts of LRRK2(G2019S) mutation carriers. / 22.01.2015 / PubMed / Full text
  • Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging. / 11.2014 / PubMed / Full text

MDM2[править]

  • SENEBLOC, a long non-coding RNA suppresses senescence via p53-dependent and independent mechanisms. / 06.04.2020 / PubMed / Full text
  • Disruption of Robo2-Baiap2 integrated signaling drives cystic disease. / 19.09.2019 / PubMed / Full text
  • Senescence-induced immunophenotype, gene expression and electrophysiology changes in human amniocytes. / 11.2019 / PubMed / Full text
  • Hsp90β interacts with MDM2 to suppress p53-dependent senescence during skeletal muscle regeneration. / 10.2019 / PubMed / Full text
  • TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway. / 07.03.2019 / PubMed / Full text
  • Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells. / 28.02.2019 / PubMed / Full text
  • The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence. / 19.10.2018 / PubMed / Full text
  • The Dysfunctional MDM2-p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy. / 11.2018 / PubMed / Full text
  • Effect of CCNB1 silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer. / 01.2018 / PubMed / Full text
  • Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria. / 02.05.2018 / PubMed / Full text
  • Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts. / 08.05.2018 / PubMed / Full text
  • Relevance of the p53-MDM2 axis to aging. / 01.2018 / PubMed / Full text
  • Pomegranate peel extract attenuates D-galactose-induced oxidative stress and hearing loss by regulating PNUTS/PP1 activity in the mouse cochlea. / 11.2017 / PubMed / Full text
  • Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-FOXO1 pathway. / 2017 / PubMed / Full text
  • Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner. / 01.03.2017 / PubMed / Full text
  • Protection against High-Fat-Diet-Induced Obesity in MDM2 Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure. / 24.01.2017 / PubMed / Full text
  • Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence. / 28.12.2016 / PubMed / Full text
  • Roles of TP53 in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis. / 01.2017 / PubMed / Full text
  • Dynamics of ARF regulation that control senescence and cancer. / 11.2016 / PubMed / Full text
  • Breaking a paradigm: IL-6/STAT3 signaling suppresses metastatic prostate cancer upon ARF expression. / 03.2016 / PubMed / Full text
  • Combined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses. / 08.2015 / PubMed / Full text
  • BI2536--A PLK inhibitor augments paclitaxel efficacy in suppressing tamoxifen induced senescence and resistance in breast cancer cells. / 08.2015 / PubMed / Full text
  • NQO1 Stabilizes p53 in Response to Oncogene-Induced Senescence. / 2015 / PubMed / Full text
  • MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition. / 10.04.2015 / PubMed / Full text
  • Senescence induction in renal carcinoma cells by Nutlin-3: a potential therapeutic strategy based on MDM2 antagonism. / 28.10.2014 / PubMed / Full text
  • Germline genetics of the p53 pathway affect longevity in a gender specific manner. / 2014 / PubMed / Full text

SIRT2[править]

  • Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the SIRT2-dependent H4K16 deacetylation pathway. / 24.01.2020 / PubMed / Full text
  • SIRT2 functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes. / 01.09.2019 / PubMed / Full text
  • Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
  • Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. / 22.01.2019 / PubMed / Full text
  • Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and [i]C. elegans[/i]. / 20.11.2018 / PubMed / Full text
  • Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes. / 01.05.2019 / PubMed / Full text
  • High expression of CPT1b in skeletal muscle in metabolically healthy older subjects. / 04.2019 / PubMed / Full text
  • Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans. / 2017 / PubMed / Full text
  • Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. / 12.2017 / PubMed / Full text
  • SIRT2 Acts as a Cardioprotective Deacetylase in Pathological Cardiac Hypertrophy. / 21.11.2017 / PubMed / Full text
  • Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. / 2017 / PubMed / Full text
  • Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders. / 03.2017 / PubMed / Full text
  • Resistance training and redox homeostasis: Correlation with age-associated genomic changes. / 12.2016 / PubMed / Full text
  • Aging-related 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurochemial and behavioral deficits and redox dysfunction: improvement by AK-7. / 09.2016 / PubMed / Full text
  • Increased expression of SIRT2 is a novel marker of cellular senescence and is dependent on wild type p53 status. / 17.07.2016 / PubMed / Full text
  • Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins. / 15.06.2016 / PubMed / Full text
  • Sirtuins, Cell Senescence, and Vascular Aging. / 05.2016 / PubMed / Full text
  • The expression levels of the sirtuins in patients with BCC. / 05.2016 / PubMed / Full text
  • Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum. / 11.2015 / PubMed / Full text
  • Localization of sirtuins (SIRT1-7) in the aged mouse inner ear. / 2016 / PubMed / Full text
  • Aging-related rotenone-induced neurochemical and behavioral deficits: role of SIRT2 and redox imbalance, and neuroprotection by AK-7. / 2015 / PubMed / Full text
  • Differential expression of sirtuins in the aging rat brain. / 2015 / PubMed / Full text
  • Polymorphisms Falling Within Putative miRNA Target Sites in the 3'UTR Region of SIRT2 and DRD2 Genes Are Correlated With Human Longevity. / 05.2016 / PubMed / Full text
  • The role of melatonin, sirtuin2 and FoXO1 transcription factor in the aging process of colon in male rats. / 02.2015 / PubMed / Full text
  • [[[SIRT2]], a multi-talented deacetylase]. / 05.2014 / PubMed / Full text
  • SIRT2 induces the checkpoint kinase BubR1 to increase lifespan. / 01.07.2014 / PubMed / Full text

APC[править]

  • Differences between blacks and whites in well-being, beliefs, emotional states, behaviors and survival, 1978-2014. / 2020 / PubMed / Full text
  • Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging. / 07.08.2020 / PubMed / Full text
  • Burden of musculoskeletal disorders in Iran during 1990-2017: estimates from the Global Burden of Disease Study 2017. / 10.07.2020 / PubMed / Full text
  • Fall-related mortality trends in older Japanese adults aged ≥65 years: a nationwide observational study. / 11.12.2019 / PubMed / Full text
  • Stroke Mortality Rates and Trends in Romania, 1994-2017. / 12.2019 / PubMed / Full text
  • A new approach to quantifying the EEG during walking: Initial evidence of gait related potentials and their changes with aging and dual tasking. / 15.10.2019 / PubMed / Full text
  • Risk-period-cohort approach for averting identification problems in longitudinal models. / 2019 / PubMed / Full text
  • Wnt Signaling Mediates the Aging-Induced Differentiation Impairment of Intestinal Stem Cells. / 06.2019 / PubMed / Full text
  • Biased estimation of trends in cohort effects: the problems with age-period-cohort models in ecology. / 12.2018 / PubMed / Full text
  • [Gender Differences in Projected Life Expectancy in Japan (2023-2047) Determined by Bayesian Age-Period-Cohort Analysis]. / 2018 / PubMed / Full text
  • Activated Yes-Associated Protein Accelerates Cell Cycle, Inhibits Apoptosis, and Delays Senescence in Human Periodontal Ligament Stem Cells. / 2018 / PubMed / Full text
  • Activating the Anaphase Promoting Complex to Enhance Genomic Stability and Prolong Lifespan. / 27.06.2018 / PubMed / Full text
  • Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04. / 2018 / PubMed / Full text
  • [Role and alterations of DNA methylation during the aging and cancer]. / 01.2018 / PubMed / Full text
  • MicroRNA-210-mediated proliferation, survival, and angiogenesis promote cardiac repair post myocardial infarction in rodents. / 12.2017 / PubMed / Full text
  • IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo. / 01.04.2017 / PubMed / Full text
  • Standard expected years of life lost due to tuberculosis in Poland. / 01.02.2017 / PubMed / Full text
  • The effects of New York City's coordinated public health programmes on mortality through 2011. / 01.08.2017 / PubMed / Full text
  • Regional variation in coronary heart disease mortality trends in Portugal, 1981-2012. / 01.12.2016 / PubMed / Full text
  • Mitotic degradation of yeast Fkh1 by the Anaphase Promoting Complex is required for normal longevity, genomic stability and stress resistance. / 04.2016 / PubMed / Full text
  • Breast Cancer Trend in Iran from 2000 to 2009 and Prediction till 2020 using a Trend Analysis Method. / 2016 / PubMed / Full text
  • Secular trend analysis of lung cancer incidence in Sihui city, China between 1987 and 2011. / 31.07.2015 / PubMed / Full text
  • Black-white disparity in disability among U.S. older adults: age, period, and cohort trends. / 09.2014 / PubMed / Full text
  • Conserved mechanisms of tumorigenesis in the Drosophila adult midgut. / 2014 / PubMed / Full text
  • CD4 T cell defects in the aged: causes, consequences and strategies to circumvent. / 06.2014 / PubMed / Full text

CA2[править]

  • Maintaining Aging Hippocampal Function with Safe and Feasible Shaking Exercise in SAMP10 Mice. / 2020 / PubMed / Full text
  • One-year Follow-up Study of Hippocampal Subfield Atrophy in Alzheimer's Disease and Normal Aging. / 2019 / PubMed / Full text
  • Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory. / 29.10.2019 / PubMed / Full text
  • Early disruption of parvalbumin expression and perineuronal nets in the hippocampus of the Tg2576 mouse model of Alzheimer's disease can be rescued by enriched environment. / 12.2018 / PubMed / Full text
  • Protracted hippocampal development is associated with age-related improvements in memory during early childhood. / 01.07.2018 / PubMed / Full text
  • Neurodevelopment and behavior in neonatal OXYS rats with genetically determined accelerated senescence. / 15.02.2018 / PubMed / Full text
  • Effect of Chronic Administration of Resveratrol on Cognitive Performance during Aging Process in Rats. / 2017 / PubMed / Full text
  • Time of day but not aging regulates 5-HT receptor binding sites in the hamster hippocampus. / 01.01.2018 / PubMed / Full text
  • Cytoarchitectonically-driven MRI atlas of nonhuman primate hippocampus: Preservation of subfield volumes in aging. / 05.2019 / PubMed / Full text
  • Hippocampal sclerosis, hippocampal neuron loss patterns and TDP-43 in the aged population. / 07.2018 / PubMed / Full text
  • Aging Does Not Affect Axon Initial Segment Structure and Somatic Localization of Tau Protein in Hippocampal Neurons of Fischer 344 Rats. / 07-08.2017 / PubMed / Full text
  • Dancing or Fitness Sport? The Effects of Two Training Programs on Hippocampal Plasticity and Balance Abilities in Healthy Seniors. / 2017 / PubMed / Full text
  • Comparison of the influence of two models of mild stress on hippocampal brain-derived neurotrophin factor (BDNF) immunoreactivity in old age rats. / 2017 / PubMed / Full text
  • Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis. / 01.2017 / PubMed / Full text
  • Depressive symptoms modify age effects on hippocampal subfields in older adults. / 10.2017 / PubMed / Full text
  • Roles of hippocampal subfields in verbal and visual episodic memory. / 15.01.2017 / PubMed / Full text
  • Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome. / 06.01.2016 / PubMed / Full text
  • Changes in serotonin (5-HT) and brain-derived neurotrophic factor (BDFN) expression in frontal cortex and hippocampus of aged rat treated with high tryptophan diet. / 10.2015 / PubMed / Full text
  • Hippocampal cytogenesis and spatial learning in senile rats exposed to chronic variable stress: effects of previous early life exposure to mild stress. / 2015 / PubMed / Full text
  • Longitudinal reproducibility of automatically segmented hippocampal subfields: A multisite European 3T study on healthy elderly. / 09.2015 / PubMed / Full text
  • Fluid percussion injury device for the precise control of injury parameters. / 15.06.2015 / PubMed / Full text
  • Characterization of Periodic Acid-Schiff-Positive Granular Deposits in the Hippocampus of SJL/J Mice. / 07.2015 / PubMed / Full text
  • Peripheral antioxidant markers are associated with total hippocampal and CA3/dentate gyrus volume in MDD and healthy controls-preliminary findings. / 30.12.2014 / PubMed / Full text
  • Hippocampal subfield volumes at 7T in early Alzheimer's disease and normal aging. / 09.2014 / PubMed / Full text
  • Moringa oleifera mitigates memory impairment and neurodegeneration in animal model of age-related dementia. / 2013 / PubMed / Full text

TLR2[править]

  • Changes in salivary microbial sensing proteins CD14 and TLR2 with aging. / 07.2020 / PubMed / Full text
  • Culture Model for Non-human Primate Choroid Plexus. / 2019 / PubMed / Full text
  • Changes in fetal membrane histology with cervical insufficiency and transabdominal cerclage. / 08.2019 / PubMed / Full text
  • Aging leads to dysfunctional innate immune responses to TLR2 and TLR4 agonists. / 09.2019 / PubMed / Full text
  • The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease. / 10.2018 / PubMed / Full text
  • Aging modulates microglia phenotypes in neuroinflammation of MPTP-PD mice. / 01.10.2018 / PubMed / Full text
  • Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice. / 24.08.2018 / PubMed / Full text
  • Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging. / 05.2018 / PubMed / Full text
  • TLR4 and TLR2 activation is differentially associated with age during Parkinson's disease. / 01.2018 / PubMed / Full text
  • Role of pattern recognition receptors of the neurovascular unit in inflamm-aging. / 01.11.2017 / PubMed / Full text
  • Ionizing radiation reduces ADAM10 expression in brain microvascular endothelial cells undergoing stress-induced senescence. / 04.2017 / PubMed / Full text
  • Aging-related Atg5 defect impairs neutrophil extracellular traps formation. / 08.2017 / PubMed / Full text
  • Chronoinflammaging in Alzheimer; A systematic review on the roles of toll like receptor 2. / 15.02.2017 / PubMed / Full text
  • Aged B cells alter immune regulation of allografts in mice. / 11.2016 / PubMed / Full text
  • Estrogen receptors alpha mediates postischemic inflammation in chronically estrogen-deprived mice. / 04.2016 / PubMed / Full text
  • Effects of aerobic training on markers of autophagy in the elderly. / 04.2016 / PubMed / Full text
  • Reduced levels of cytosolic DNA sensor AIM2 are associated with impaired cytokine responses in healthy elderly. / 06.2016 / PubMed / Full text
  • Immune ageing and susceptibility to Streptococcus pneumoniae. / 06.2016 / PubMed / Full text
  • Monocyte Phenotype and Polyfunctionality Are Associated With Elevated Soluble Inflammatory Markers, Cytomegalovirus Infection, and Functional and Cognitive Decline in Elderly Adults. / 05.2016 / PubMed / Full text
  • Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. / 06.2015 / PubMed / Full text
  • Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal TLR4 activation in aged rats. / 05.2015 / PubMed / Full text
  • Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture. / 05.2015 / PubMed / Full text
  • Aging does not affect the ability of human monocyte-derived dendritic cells to phagocytose Candida albicans. / 12.2015 / PubMed / Full text
  • Cardiac autonomic dysfunction: particulate air pollution effects are modulated by epigenetic immunoregulation of Toll-like receptor 2 and dietary flavonoid intake. / 27.01.2015 / PubMed / Full text
  • Bacteria and Toll-like receptor and cytokine mRNA expression profiles associated with canine arthritis. / 15.08.2014 / PubMed / Full text

AFM[править]

  • Photocatalytic aging process of Nano-TiO coated polypropylene microplastics: Combining atomic force microscopy and infrared spectroscopy (AFM-IR) for nanoscale chemical characterization. / 15.02.2021 / PubMed / Full text
  • Nanoscale infrared, thermal and mechanical properties of aged microplastics revealed by an atomic force microscopy coupled with infrared spectroscopy (AFM-IR) technique. / 20.11.2020 / PubMed / Full text
  • Detecting zeta potential of polydimethylsiloxane (PDMS) in electrolyte solutions with atomic force microscope. / 15.10.2020 / PubMed / Full text
  • Recent Applications of Advanced Atomic Force Microscopy in Polymer Science: A Review. / 17.05.2020 / PubMed / Full text
  • Active fractions of mannoproteins derived from yeast cell wall stimulate innate and acquired immunity of adult and elderly dogs. / 03.2020 / PubMed / Full text
  • The Effect of Waste Engine Oil and Waste Polyethylene on UV Aging Resistance of Asphalt. / 06.03.2020 / PubMed / Full text
  • Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans. / 25.02.2020 / PubMed / Full text
  • Nanomechanical insights: Amyloid beta oligomer-induced senescent brain endothelial cells. / 01.12.2019 / PubMed / Full text
  • Application of atomic force microscopy in the analysis of time since deposition (TSD) of red blood cells in bloodstains: A forensic analysis. / 08.2019 / PubMed / Full text
  • Iceland spar calcite: Humidity and time effects on surface properties and their reversibility. / 01.04.2019 / PubMed / Full text
  • Zebrafish as a model to study bone maturation: Nanoscale structural and mechanical characterization of age-related changes in the zebrafish vertebral column. / 08.2018 / PubMed / Full text
  • Multiscale Poroviscoelastic Compressive Properties of Mouse Supraspinatus Tendons Are Altered in Young and Aged Mice. / 01.05.2018 / PubMed / Full text
  • Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease. / 11.2017 / PubMed / Full text
  • Effect of intra-oral aging on t→m phase transformation, microstructure, and mechanical properties of Y-TZP dental ceramics. / 08.2017 / PubMed / Full text
  • The Effect of Brushing and Aging on the Staining and Smoothness of Resin Composites. / 04.2017 / PubMed / Full text
  • Frequency-modulated atomic force microscopy localises viscoelastic remodelling in the ageing sheep aorta. / 12.2016 / PubMed / Full text
  • Changes in surface characteristics of two different resin composites after 1 year water storage: An SEM and AFM study. / 11.2016 / PubMed / Full text
  • Wide bandwidth nanomechanical assessment of murine cartilage reveals protection of aggrecan knock-in mice from joint-overuse. / 14.06.2016 / PubMed / Full text
  • Effect of at-home bleaching with different thickeners and aging on physical properties of a nanocomposite. / 01-03.2016 / PubMed / Full text
  • Interaction of intraocular lenses with fibronectin and human lens epithelial cells: Effect of chemical composition and aging. / 12.2015 / PubMed / Full text
  • β-Hydroxy-β-methylbutyrate (HMB) supplementation and resistance exercise significantly reduce abdominal adiposity in healthy elderly men. / 04.2015 / PubMed / Full text
  • Atomic force microscopy reveals age-dependent changes in nanomechanical properties of the extracellular matrix of native human menisci: implications for joint degeneration and osteoarthritis. / 11.2014 / PubMed / Full text
  • In situ atomic force microscopy analysis of morphology and particle size changes in lithium iron phosphate cathode during discharge. / 01.06.2014 / PubMed / Full text
  • Load cycling enhances bioactivity at the resin-dentin interface. / 07.2014 / PubMed / Full text

GSC[править]

  • [i]mastermind[/i] regulates niche ageing independently of the [i]Notch[/i] pathway in the [i]Drosophila[/i] ovary. / 29.11.2019 / PubMed / Full text
  • Germline stem cell homeostasis. / 2019 / PubMed / Full text
  • Endocrine regulation of female germline stem cells in the fruit fly Drosophila melanogaster. / 02.2019 / PubMed / Full text
  • Generation of Inducible Gene-Switched GAL4 Expressed in the [i]Drosophila[/i] Female Germline Stem Cell Niche. / 05.06.2019 / PubMed / Full text
  • YAP/Yorkie in the germline modulates the age-related decline of germline stem cells and niche cells. / 2019 / PubMed / Full text
  • Diminished Jak/STAT Signaling Causes Early-Onset Aging Defects in Stem Cell Cytokinesis. / 21.01.2019 / PubMed / Full text
  • JNK signaling triggers spermatogonial dedifferentiation during chronic stress to maintain the germline stem cell pool in the [i]Drosophila[/i] testis. / 09.07.2018 / PubMed / Full text
  • Age-related differences in BOLD modulation to cognitive control costs in a multitasking paradigm: Global switch, local switch, and compatibility-switch costs. / 15.05.2018 / PubMed / Full text
  • Modelling glioblastoma tumour-host cell interactions using adult brain organotypic slice co-culture. / 22.02.2018 / PubMed / Full text
  • Loss of [i]foxo[/i] rescues stem cell aging in [i]Drosophila[/i] germ line. / 19.09.2017 / PubMed / Full text
  • DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation. / 04.2017 / PubMed / Full text
  • Antithrombotic agents intake prior to injury does not affect outcome after a traumatic brain injury in hospitalized elderly patients. / 04.2017 / PubMed / Full text
  • Suberoylanilide hydroxamic acid represses glioma stem-like cells. / 18.11.2016 / PubMed / Full text
  • Flavonoids and darkness lower PCD in senescing Vitis vinifera suspension cell cultures. / 26.10.2016 / PubMed / Full text
  • DNA damage-induced Lok/CHK2 activation compromises germline stem cell self-renewal and lineage differentiation. / 01.12.2016 / PubMed / Full text
  • The Wnt pathway limits BMP signaling outside of the germline stem cell niche in Drosophila ovaries. / 01.09.2016 / PubMed / Full text
  • Nuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations. / 01-03.2016 / PubMed / Full text
  • Senescence from glioma stem cell differentiation promotes tumor growth. / 05.02.2016 / PubMed / Full text
  • Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence. / 24.08.2015 / PubMed / Full text
  • Microglial voltage-gated sodium channels modulate cellular response in Alzheimer's disease--a new perspective on an old problem. / 2015 / PubMed
  • Y-27632, a ROCK inhibitor, delays senescence of putative murine salivary gland stem cells in culture. / 06.2015 / PubMed / Full text
  • Notch signaling mediates the age-associated decrease in adhesion of germline stem cells to the niche. / 12.2014 / PubMed / Full text
  • Aging and insulin signaling differentially control normal and tumorous germline stem cells. / 02.2015 / PubMed / Full text
  • [The opportunity to use combined stem cells transplantation for haemopoesis activation in the old and mature laboratory animals under the conditions of ionizing radiation]. / 2014 / PubMed

HGF[править]

  • Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4 T cell subsets. / 19.11.2020 / PubMed / Full text
  • Hepatocyte growth factor (HGF) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling pathways. / 31.07.2020 / PubMed / Full text
  • Phenytoin sodium-ameliorated gingival fibroblast aging is associated with autophagy. / 10.2020 / PubMed / Full text
  • Impaired integrin α /β -mediated hepatocyte growth factor release by stellate cells of the aged liver. / 04.2020 / PubMed / Full text
  • Evaluation of the biological behaviour of various dental implant abutment materials on attachment and viability of human gingival fibroblasts. / 07.2019 / PubMed / Full text
  • Characterization of aged rat vocal fold fibroblasts. / 03.2019 / PubMed / Full text
  • Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults. / 09.2018 / PubMed / Full text
  • Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging. / 26.10.2018 / PubMed / Full text
  • Hepatocyte growth factor is a potential biomarker for osteoproliferation and osteoporosis in ankylosing spondylitis. / 02.2019 / PubMed / Full text
  • Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor. / 09.03.2018 / PubMed / Full text
  • HGF and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the SIRT1/FOXO1 Signaling Pathway. / 2018 / PubMed / Full text
  • Cell-size-dependent upregulation of HGF expression in dermal fibroblasts: Impact on human skin connective tissue aging. / 12.2017 / PubMed / Full text
  • Oxidative stress contributes to hepatocyte growth factor-dependent pro-senescence activity of ovarian cancer cells. / 09.2017 / PubMed / Full text
  • Estrogen modulates mesenchyme-epidermis interactions in the adult nipple. / 15.04.2017 / PubMed / Full text
  • Enhanced Functional Recovery from Spinal Cord Injury in Aged Mice after Stem Cell Transplantation through HGF Induction. / 14.03.2017 / PubMed / Full text
  • Necroptosis Induced by Ad-HGF Activates Endogenous C-Kit Cardiac Stem Cells and Promotes Cardiomyocyte Proliferation and Angiogenesis in the Infarcted Aged Heart. / 2016 / PubMed / Full text
  • Ovarian cancer-derived ascitic fluids induce a senescence-dependent pro-cancerogenic phenotype in normal peritoneal mesothelial cells. / 10.2016 / PubMed / Full text
  • Influence of aging on the quantity and quality of human cardiac stem cells. / 07.03.2016 / PubMed / Full text
  • Senescent peritoneal mesothelium induces a pro-angiogenic phenotype in ovarian cancer cells in vitro and in a mouse xenograft model in vivo. / 01.2016 / PubMed / Full text
  • Macrophage migration inhibitory factor confers resistance to senescence through CD74-dependent AMPK-FOXO3a signaling in mesenchymal stem cells. / 22.04.2015 / PubMed / Full text
  • Prevention of hair graying by factors that promote the growth and differentiation of melanocytes. / 08.2014 / PubMed / Full text
  • Low-power laser irradiation fails to improve liver regeneration in elderly rats at 48 h after 70 % resection. / 09.2015 / PubMed / Full text
  • Effect of AST on age-associated changes of vocal folds in a rat model. / 10.2014 / PubMed / Full text
  • The role of growth factors in maintenance of stemness in bone marrow-derived mesenchymal stem cells. / 28.02.2014 / PubMed / Full text

SOX2[править]

  • Multiple nanosecond pulsed electric fields stimulation with conductive poly(l-lactic acid)/carbon nanotubes films maintains the multipotency of mesenchymal stem cells during prolonged in vitro culture. / 08.2020 / PubMed / Full text
  • Subpopulations of miniature pig mesenchymal stromal cells with different differentiation potentials differ in the expression of octamer-binding transcription factor 4 and sex determining region Y-box 2. / 03.2020 / PubMed / Full text
  • Increased Type I and Decreased Type II Hair Cells after Deletion of Sox2 in the Developing Mouse Utricle. / 01.12.2019 / PubMed / Full text
  • 'Stemness' and 'senescence' related escape pathways are dose dependent in lung cancer cells surviving post irradiation. / 01.09.2019 / PubMed / Full text
  • Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis. / 30.04.2019 / PubMed / Full text
  • The senescent status of endothelial cells affects proliferation, inflammatory profile and SOX2 expression in bone marrow-derived mesenchymal stem cells. / 06.2019 / PubMed / Full text
  • Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart. / 07.01.2019 / PubMed / Full text
  • A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. / 02.10.2018 / PubMed / Full text
  • MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1. / 12.2018 / PubMed / Full text
  • Centenarians Overexpress Pluripotency-Related Genes. / 16.08.2019 / PubMed / Full text
  • MYC Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition. / 10.04.2018 / PubMed / Full text
  • SOX2 expression diminishes with ageing in several tissues in mice and humans. / 01.2019 / PubMed / Full text
  • Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence. / 15.10.2017 / PubMed / Full text
  • ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors. / 09.2017 / PubMed / Full text
  • Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. / 01.09.2017 / PubMed / Full text
  • Role of p16 and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells. / 08.2017 / PubMed / Full text
  • Autophagic homeostasis is required for the pluripotency of cancer stem cells. / 02.2017 / PubMed / Full text
  • The p53 Pathway Controls SOX2-Mediated Reprogramming in the Adult Mouse Spinal Cord. / 11.10.2016 / PubMed / Full text
  • Sox2-Deficient Müller Glia Disrupt the Structural and Functional Maturation of the Mammalian Retina. / 03.2016 / PubMed / Full text
  • mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance. / 2016 / PubMed / Full text
  • Disentangling the aneuploidy and senescence paradoxes: a study of triploid breast cancers non-responsive to neoadjuvant therapy. / 04.2016 / PubMed / Full text
  • Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide. / 2015 / PubMed / Full text
  • Critical role of the miR-200 family in regulating differentiation and proliferation of neurons. / 06.2015 / PubMed / Full text
  • Localization of juxtacrine factor ephrin-B2 in pituitary stem/progenitor cell niches throughout life. / 03.2015 / PubMed / Full text

BRAF[править]

  • Conditional reprograming culture conditions facilitate growth of lower grade glioma models. / 01.12.2020 / PubMed / Full text
  • Active notch protects MAPK activated melanoma cell lines from MEK inhibitor cobimetinib. / 14.11.2020 / PubMed / Full text
  • Mitochondrial metabolic reprograming via BRAF inhibition ameliorates senescence. / 15.10.2019 / PubMed / Full text
  • Deciphering the genotype and phenotype of hairy cell leukemia: clues for diagnosis and treatment. / 08.2019 / PubMed / Full text
  • A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient. / 09.2019 / PubMed / Full text
  • Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf -Induced Tumorigenesis. / 11.02.2019 / PubMed / Full text
  • Acquired resistance to BRAFi reverses senescence-like phenotype in mutant BRAF melanoma. / 07.08.2018 / PubMed / Full text
  • Cancer modeling by Transgene Electroporation in Adult Zebrafish (TEAZ). / 27.09.2018 / PubMed / Full text
  • Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement. / 05.01.2018 / PubMed / Full text
  • Impact of Age on Outcomes with Immunotherapy for Patients with Melanoma. / 08.2017 / PubMed / Full text
  • Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing. / 14.02.2017 / PubMed / Full text
  • Detection of Reactive Oxygen Species in Cells Undergoing Oncogene-Induced Senescence. / 2017 / PubMed / Full text
  • GBM-associated mutations and altered protein expression are more common in young patients. / 25.10.2016 / PubMed / Full text
  • What makes oncogenes mutually exclusive? / 03.07.2017 / PubMed / Full text
  • Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression. / 05.04.2016 / PubMed / Full text
  • Combination with γ-secretase inhibitor prolongs treatment efficacy of BRAF inhibitor in BRAF-mutated melanoma cells. / 28.06.2016 / PubMed / Full text
  • Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations. / 23.02.2016 / PubMed / Full text
  • Encorafenib (LGX818), a potent BRAF inhibitor, induces senescence accompanied by autophagy in BRAFV600E melanoma cells. / 28.01.2016 / PubMed / Full text
  • Novel Therapies for Metastatic Melanoma: An Update on Their Use in Older Patients. / 10.2015 / PubMed / Full text
  • Expression of tumor-related Rac1b antagonizes B-Raf-induced senescence in colorectal cells. / 28.12.2015 / PubMed / Full text
  • Trametinib radiosensitises RAS- and BRAF-mutated melanoma by perturbing cell cycle and inducing senescence. / 11.2015 / PubMed / Full text
  • Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma. / 07.2014 / PubMed / Full text
  • Oncogene-induced senescence distinguishes indolent from aggressive forms of pulmonary and non-pulmonary Langerhans cell histiocytosis. / 11.2014 / PubMed / Full text

CD36[править]

  • Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease. / 08.2020 / PubMed / Full text
  • Reduction of senescence-associated beta-galactosidase activity by vitamin E in human fibroblasts depends on subjects' age and cell passage number. / 07.2020 / PubMed / Full text
  • Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. / 05.2020 / PubMed / Full text
  • Human bone marrow adipocytes display distinct immune regulatory properties. / 08.2019 / PubMed / Full text
  • Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken. / 01.09.2019 / PubMed / Full text
  • Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis. / 22.01.2019 / PubMed / Full text
  • The adhesion and migration of microglia to β-amyloid (Aβ) is decreased with aging and inhibited by Nogo/NgR pathway. / 20.07.2018 / PubMed / Full text
  • Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis. / 01.11.2018 / PubMed / Full text
  • An evolutionary transcriptomics approach links CD36 to membrane remodeling in replicative senescence. / 06.08.2018 / PubMed / Full text
  • Comparative analysis of endothelial cell and sub-endothelial cell elastic moduli in young and aged mice: Role of CD36. / 25.07.2018 / PubMed / Full text
  • CD36 initiates the secretory phenotype during the establishment of cellular senescence. / 06.2018 / PubMed / Full text
  • Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation. / 05.2018 / PubMed / Full text
  • Developmental differences between neonatal and adult human erythropoiesis. / 08.2018 / PubMed / Full text
  • Effects of high-fat diet and age on the blood lipidome and circulating endocannabinoids of female C57BL/6 mice. / 01.2018 / PubMed / Full text
  • Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain. / 2017 / PubMed / Full text
  • Thyroid hormone-stimulated increases in PGC-1α and UCP2 promote life history-specific endocrine changes and maintain a lipid-based metabolism. / 01.02.2017 / PubMed / Full text
  • The Drosophila CD36 Homologue croquemort Is Required to Maintain Immune and Gut Homeostasis during Development and Aging. / 10.2016 / PubMed / Full text
  • Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology. / 02.2017 / PubMed / Full text
  • Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice. / 2016 / PubMed / Full text
  • Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice. / 15.01.2016 / PubMed / Full text
  • Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone. / 07.2014 / PubMed / Full text
  • Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease. / 04.2014 / PubMed / Full text
  • Long-term vitamin E supplementation reduces atherosclerosis and mortality in Ldlr-/- mice, but not when fed Western style diet. / 03.2014 / PubMed / Full text

CIT[править]

  • Effect of sex on aging-related decline of dopamine transporter in healthy subjects. / 14.10.2020 / PubMed / Full text
  • The Relationship Between the Striatal Dopaminergic Neuronal and Cognitive Function With Aging. / 2020 / PubMed / Full text
  • Initial Dietary Protein Intake Influence Muscle Function Adaptations in Older Men and Women Following High-Intensity Interval Training Combined with Citrulline. / 22.07.2019 / PubMed / Full text
  • I-FP-CIT striatal binding ratios do not decrease significantly with age in older adults. / 06.2019 / PubMed / Full text
  • Effect of High-Intensity Interval Training Combined with L-Citrulline Supplementation on Functional Capacities and Muscle Function in Dynapenic-Obese Older Adults. / 17.12.2018 / PubMed / Full text
  • The Six-Item Cognitive Impairment Test Is Associated with Adverse Outcomes in Acutely Hospitalized Older Patients: A Prospective Cohort Study. / 05-08.2018 / PubMed / Full text
  • Dopaminergic imaging separates normal pressure hydrocephalus from its mimics. / 10.2018 / PubMed / Full text
  • Lower Cognitive Function in Older Patients with Lower Muscle Strength and Muscle Mass. / 2018 / PubMed / Full text
  • Citrulline counteracts overweight- and aging-related effects on adiponectin and leptin gene expression in rat white adipose tissue. / 2015 / PubMed / Full text
  • Overcoming Barriers of Age to Enhance Efficacy of Cancer Immunotherapy: The Clout of the Extracellular Matrix. / 2018 / PubMed / Full text
  • Validation of the 6-Item Cognitive Impairment Test and the 4AT test for combined delirium and dementia screening in older Emergency Department attendees. / 01.01.2018 / PubMed / Full text
  • Octogenarian liver grafts: Is their use for transplant currently justified? / 07.05.2017 / PubMed / Full text
  • Citrulline stimulates locomotor activity in aged rats: Implication of the dopaminergic pathway. / 06.2017 / PubMed / Full text
  • Age-related effects and gender differences in Japanese healthy controls for [ I] FP-CIT SPECT. / 06.2017 / PubMed / Full text
  • The changes of individual carotid artery wall layer by aging and carotid intima-media thickness value for high risk. / 12.2016 / PubMed / Full text
  • Melodic Contour Identification Reflects the Cognitive Threshold of Aging. / 2016 / PubMed / Full text
  • Effects of Donor Age and Cold Ischemia on Liver Transplantation Outcomes According to the Severity of Recipient Status. / 02.2016 / PubMed / Full text
  • Aging and chronic administration of serotonin-selective reuptake inhibitor citalopram upregulate Sirt4 gene expression in the preoptic area of male mice. / 2015 / PubMed / Full text
  • Effects of aging and gender on striatal and extrastriatal [123I]FP-CIT binding in Parkinson's disease. / 04.2015 / PubMed / Full text
  • Dopamine transporter imaging in the aged rat: a [¹²³I]FP-CIT SPECT study. / 04.2015 / PubMed / Full text
  • Uneven age effects of [(18)F]FP-CIT binding in the striatum of Parkinson's disease. / 11.2014 / PubMed / Full text
  • Citrulline induces fatty acid release selectively in visceral adipose tissue from old rats. / 09.2014 / PubMed / Full text
  • Prognostic factors for kidney allograft survival in the Eurotransplant Senior Program. / 01.05.2014 / PubMed / Full text

DCX[править]

  • GSK-3β activation accelerates early-stage consumption of Hippocampal Neurogenesis in senescent mice. / 2020 / PubMed / Full text
  • Doublecortin and IGF-1R protein levels are reduced in spite of unchanged DNA methylation in the hippocampus of aged rats. / 04.2020 / PubMed / Full text
  • Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients. / 06.06.2019 / PubMed / Full text
  • Age-related changes in Ki-67 and DCX expression in the BALB/ c mouse (Mus Musculus) brain. / 02.2019 / PubMed / Full text
  • Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol. / 11.09.2018 / PubMed / Full text
  • Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice. / 04.09.2018 / PubMed / Full text
  • Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning. / 02.2019 / PubMed / Full text
  • Hippocampal neurogenesis in the C57BL/6J mice at early adulthood following prenatal alcohol exposure. / 04.2018 / PubMed / Full text
  • Puerarin and Amlodipine Improvement of D-Galactose-Induced Impairments of Behaviour and Neurogenesis in Mouse Dentate Gyrus: Correlation with Glucocorticoid Receptor Expression. / 11.2017 / PubMed / Full text
  • Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers. / 10.2017 / PubMed / Full text
  • Early-life decline in neurogenesis markers and age-related changes of TrkB splice variant expression in the human subependymal zone. / 07.2017 / PubMed / Full text
  • Dehydroepiandrosterone increases the number and dendrite maturation of doublecortin cells in the dentate gyrus of middle age male Wistar rats exposed to chronic mild stress. / 15.03.2017 / PubMed / Full text
  • Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis. / 03.2017 / PubMed / Full text
  • Postnatal maturation of mouse medullo-spinal cerebrospinal fluid-contacting neurons. / 20.02.2017 / PubMed / Full text
  • Topiramate Improves Neuroblast Differentiation of Hippocampal Dentate Gyrus in the D-Galactose-Induced Aging Mice via Its Antioxidant Effects. / 07.2017 / PubMed / Full text
  • Adenosine A1 receptor antagonist mitigates deleterious effects of sleep deprivation on adult neurogenesis and spatial reference memory in rats. / 19.11.2016 / PubMed / Full text
  • Sex-Specific Effects of Prenatal Stress on Memory and Markers of Neuronal Activity in Juvenile Rats. / 2016 / PubMed / Full text
  • MeHg Suppressed Neuronal Potency of Hippocampal NSCs Contributing to the Puberal Spatial Memory Deficits. / 08.2016 / PubMed / Full text
  • Hypercrosslinked Additives for Ageless Gas-Separation Membranes. / 05.02.2016 / PubMed / Full text
  • Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus. / 12.2016 / PubMed / Full text
  • Effects of Ginko biloba leaf extract on the neurogenesis of the hippocampal dentate gyrus in the elderly mice. / 06.2016 / PubMed / Full text
  • Persistent loss of hippocampal neurogenesis and increased cell death following adolescent, but not adult, chronic ethanol exposure. / 2014 / PubMed / Full text
  • Lactobacillus pentosus var. plantarum C29 ameliorates memory impairment and inflammaging in a D-galactose-induced accelerated aging mouse model. / 06.2014 / PubMed / Full text

F3[править]

  • A Comprehensive Analysis of Age and Gender Effects in European Portuguese Oral Vowels. / 05.12.2020 / PubMed / Full text
  • Prenatal exposure to an environmentally relevant phthalate mixture accelerates biomarkers of reproductive aging in a multiple and transgenerational manner in female mice. / 28.10.2020 / PubMed / Full text
  • Combining Frontal Transcranial Direct Current Stimulation With Walking Rehabilitation to Enhance Mobility and Executive Function: A Pilot Clinical Trial. / 18.08.2020 / PubMed / Full text
  • Multigenerational exposure to TiO nanoparticles in soil stimulates stress resistance and longevity of survived C. elegans via activating insulin/IGF-like signaling. / 08.2020 / PubMed / Full text
  • Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice. / 12.09.2019 / PubMed / Full text
  • Transgenerational Effects of Extended Dauer Diapause on Starvation Survival and Gene Expression Plasticity in [i]Caenorhabditis elegans[/i]. / 09.2018 / PubMed / Full text
  • Influence of Supplemental Protein on the Life Expectancy and Reproduction of the Chinese Citrus Fruit Fly, Bactrocera minax (Enderlein) (Tetradacus minax) (Diptera: Tephritidae). / 01.03.2018 / PubMed / Full text
  • Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice. / 14.03.2018 / PubMed / Full text
  • Multigenerational effects of 4-methylbenzylidene camphor (4-MBC) on the survival, development and reproduction of the marine copepod Tigriopus japonicus. / 01.2018 / PubMed / Full text
  • Effects of Aging on Vocal Fundamental Frequency and Vowel Formants in Men and Women. / 09.2018 / PubMed / Full text
  • Shedding light on gray(ing) areas: Connectivity and task switching dynamics in aging. / 03.2018 / PubMed / Full text
  • Chronic exposure of zinc oxide nanoparticles causes deviant phenotype in Drosophila melanogaster. / 05.04.2017 / PubMed / Full text
  • Treatment of Chronic Hepatitis C in the Aged - Does It Impact Life Expectancy? A Decision Analysis. / 2016 / PubMed / Full text
  • Transgenerational programming of longevity and reproduction by post-eclosion dietary manipulation in Drosophila. / 05.2016 / PubMed / Full text
  • Spectrographic Acoustic Vocal Characteristics of Elderly Women Engaged in Aerobics. / 09.2016 / PubMed / Full text
  • Fat and carbohydrate intake over three generations modify growth, metabolism and cardiovascular phenotype in female mice in an age-related manner. / 2015 / PubMed / Full text
  • Effect of semolina-jaggery diet on survival and development of Drosophila melanogaster. / 2015 / PubMed / Full text
  • Differential regulation of apoptosis in slow and fast twitch muscles of aged female F344BN rats. / 2015 / PubMed / Full text
  • Dexmedetomidine and regulation of splenic sympathetic nerve discharge in aged F344 rats. / 07.2015 / PubMed / Full text
  • Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts. / 2015 / PubMed / Full text
  • Docosahexaenoic acid in Arctic charr (Salvelinus alpinus): the importance of dietary supply and physiological response during the entire growth period. / 03.2015 / PubMed / Full text
  • Starvation-induced transgenerational inheritance of small RNAs in C. elegans. / 17.07.2014 / PubMed / Full text
  • Air pollution and gene-specific methylation in the Normative Aging Study: association, effect modification, and mediation analysis. / 03.2014 / PubMed / Full text

GHR[править]

  • Tissue-Specific GHR Knockout Mice: An Updated Review. / 2020 / PubMed / Full text
  • The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver. / 04.2019 / PubMed / Full text
  • Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes. / 12.2018 / PubMed / Full text
  • Effects of rapamycin on growth hormone receptor knockout mice. / 13.02.2018 / PubMed / Full text
  • Disruption of the GH receptor gene in adult mice and in insulin sensitive tissues. / 02.2018 / PubMed / Full text
  • The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature. / 06.2017 / PubMed / Full text
  • Differential effects of early-life nutrient restriction in long-lived GHR-KO and normal mice. / 06.2017 / PubMed / Full text
  • Brain Structure and Function Associated with Younger Adults in Growth Hormone Receptor-Deficient Humans. / 15.02.2017 / PubMed / Full text
  • Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging. / 01.03.2017 / PubMed / Full text
  • Growth hormone receptor expression in human gluteal versus abdominal subcutaneous adipose tissue: Association with body shape. / 05.2016 / PubMed / Full text
  • The somatotropic axis and aging: Benefits of endocrine defects. / 04.2016 / PubMed / Full text
  • Growth factors, aging and age-related diseases. / 06.2016 / PubMed / Full text
  • Correlation Analysis Between Expression Levels of Hepatic Growth Hormone Receptor, Janus Kinase 2, Insulin-Like Growth Factor-I Genes and Dwarfism Phenotype in Bama Minipig. / 02.2015 / PubMed / Full text
  • Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice. / 12.2015 / PubMed / Full text
  • Removal of growth hormone receptor (GHR) in muscle of male mice replicates some of the health benefits seen in global GHR-/- mice. / 07.2015 / PubMed / Full text
  • Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver. / 03.2015 / PubMed / Full text
  • Conservation of pro-longevity genes among mammals. / 03.2015 / PubMed / Full text
  • Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging. / 2014 / PubMed / Full text
  • Inflammatory and Glutamatergic Homeostasis Are Involved in Successful Aging. / 03.2016 / PubMed / Full text
  • Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging. / 12.2014 / PubMed / Full text
  • Molecular evolution of growth hormone and insulin-like growth factor 1 receptors in long-lived, small-bodied mammals. / 10.10.2014 / PubMed / Full text
  • Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. / 04.03.2014 / PubMed / Full text
  • Expression of apoptosis-related genes in liver-specific growth hormone receptor gene-disrupted mice is sex dependent. / 01.2015 / PubMed / Full text

VDR[править]

  • 25-Hydroxyvitamin D positively regulates periodontal inflammaging via SOCS3/STAT signaling in diabetic mice. / 04.2020 / PubMed / Full text
  • 1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel VDR-Ezh2-p16 signal axis. / 02.2020 / PubMed / Full text
  • Active vitamin D impedes the progression of non-alcoholic fatty liver disease by inhibiting cell senescence in a rat model. / 09.2020 / PubMed / Full text
  • Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H O -induced apoptosis in rat intervertebral disc cells. / 06.2019 / PubMed / Full text
  • Vitamin D Receptor in Muscle Atrophy of Elderly Patients: A Key Element of Osteoporosis-Sarcopenia Connection. / 12.2018 / PubMed / Full text
  • Reduced vitamin D receptor (VDR) expression and plasma vitamin D levels are associated with aging-related prostate lesions. / 05.2018 / PubMed / Full text
  • VDR Activation Reduces Proteinuria and High-Glucose-Induced Injury of Kidneys and Podocytes by Regulating Wnt Signaling Pathway. / 2017 / PubMed / Full text
  • Vitamin D and the brain: Genomic and non-genomic actions. / 15.09.2017 / PubMed / Full text
  • Targeted next generation sequencing of the entire vitamin D receptor gene reveals polymorphisms correlated with vitamin D deficiency among older Filipino women with and without fragility fracture. / 03.2017 / PubMed / Full text
  • Using Hyperpolarized Xe MRI to Quantify the Pulmonary Ventilation Distribution. / 12.2016 / PubMed / Full text
  • Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. / 2016 / PubMed / Full text
  • Relationship between cardiometabolic profile, vitamin D status and BsmI polymorphism of the VDR gene in non-institutionalized elderly subjects: Cardiometabolic profile, vitamin D status and BsmI polymorphism of the VDR gene in non-institutionalized elderly subjects. / 08.2016 / PubMed / Full text
  • Impact of vitamin D receptor polymorphisms in centenarians. / 08.2016 / PubMed / Full text
  • Aging and a long-term diabetes mellitus increase expression of 1 α-hydroxylase and vitamin D receptors in the rat liver. / 12.2015 / PubMed / Full text
  • Nuclear hormone receptors: Roles of xenobiotic detoxification and sterol homeostasis in healthy aging. / 2015 / PubMed / Full text
  • Vitamin D Receptor Ablation and Vitamin D Deficiency Result in Reduced Grip Strength, Altered Muscle Fibers, and Increased Myostatin in Mice. / 12.2015 / PubMed / Full text
  • Extra-intestinal calcium handling contributes to normal serum calcium levels when intestinal calcium absorption is suboptimal. / 12.2015 / PubMed / Full text
  • Vitamin D Receptor Genotype Modulates the Correlation between Vitamin D and Circulating Levels of let-7a/b and Vitamin D Intake in an Elderly Cohort. / 2014 / PubMed / Full text
  • Vitamin D, muscle and bone: Integrating effects in development, aging and injury. / 15.07.2015 / PubMed / Full text
  • Association between vitamin D concentration and levels of sex hormones in an elderly Polish population with different genotypes of VDR polymorphisms (rs10735810, rs1544410, rs7975232, rs731236). / 15.03.2015 / PubMed / Full text
  • Effect modification by vitamin D receptor genetic polymorphisms in the association between cumulative lead exposure and pulse pressure: a longitudinal study. / 13.01.2015 / PubMed / Full text
  • Vitamin D receptor and megalin gene polymorphisms are associated with central adiposity status and changes among US adults. / 2013 / PubMed / Full text
  • Vitamin D signaling in myogenesis: potential for treatment of sarcopenia. / 2014 / PubMed / Full text

EZH2[править]

  • Linking gene expression and phenotypic changes in the developmental and evolutionary origins of osteosclerosis in the ribs of bowhead whales (Balaena mysticetus). / 09.2020 / PubMed / Full text
  • EZH2 is involved in vulnerability to neuroinflammation and depression-like behaviors induced by chronic stress in different aged mice. / 01.07.2020 / PubMed / Full text
  • A positive feedback loop between EZH2 and NOX4 regulates nucleus pulposus cell senescence in age-related intervertebral disc degeneration. / 2020 / PubMed / Full text
  • Perinatal exposure to bisphenol A impacts in the mammary gland morphology of adult Mongolian gerbils. / 04.2020 / PubMed / Full text
  • Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing ABI3BP in gallbladder cancer cells. / 07.06.2019 / PubMed / Full text
  • Epigenetic Co-Deregulation of EZH2/TET1 is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer. / 2019 / PubMed / Full text
  • Improving Treatment for Myelodysplastic Syndromes Patients. / 25.10.2018 / PubMed / Full text
  • Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration. / 25.09.2018 / PubMed / Full text
  • Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. / 05.11.2018 / PubMed / Full text
  • Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text
  • Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways. / 27.03.2018 / PubMed / Full text
  • Region specific knock-out reveals distinct roles of chromatin modifiers in adult neurogenic niches. / 2018 / PubMed / Full text
  • Conserved effect of aging on DNA methylation and association with EZH2 polycomb protein in mice and humans. / 03.2017 / PubMed / Full text
  • The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence. / 03.03.2017 / PubMed / Full text
  • Enhancer of Zeste Homolog 2 and Histone Deacetylase 9c Regulate Age-Dependent Mesenchymal Stem Cell Differentiation into Osteoblasts and Adipocytes. / 08.2016 / PubMed / Full text
  • Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy. / 10.2016 / PubMed / Full text
  • HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis. / 10.06.2016 / PubMed / Full text
  • New concept: cellular senescence in pathophysiology of cholangiocarcinoma. / 2016 / PubMed / Full text
  • SIRT1 affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing. / 24.06.2015 / PubMed / Full text
  • Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus. / 08.2015 / PubMed / Full text
  • Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes. / 2015 / PubMed / Full text
  • Luotonin-A based quinazolinones cause apoptosis and senescence via HDAC inhibition and activation of tumor suppressor proteins in HeLa cells. / 13.04.2015 / PubMed / Full text

MAPT[править]

  • Association of relative brain age with tobacco smoking, alcohol consumption, and genetic variants. / 30.01.2020 / PubMed / Full text
  • A blood-based nutritional risk index explains cognitive enhancement and decline in the multidomain Alzheimer prevention trial. / 2019 / PubMed / Full text
  • Longitudinal associations of physical activity levels with morphological and functional changes related with aging: The MAPT study. / 12.2019 / PubMed / Full text
  • Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease. / 31.10.2019 / PubMed / Full text
  • Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective. / 01.2020 / PubMed / Full text
  • Factors associated with changes of the frailty status after age 70: Findings in the MAPT study. / 06.2019 / PubMed / Full text
  • Mitophagy and NAD inhibit Alzheimer disease. / 06.2019 / PubMed / Full text
  • Cognitive changes of older adults with an equivocal amyloid load. / 04.2019 / PubMed / Full text
  • Tauopathy: A common mechanism for neurodegeneration and brain aging. / 03.2019 / PubMed / Full text
  • Cinnamaldehyde Improves Lifespan and Healthspan in [i]Drosophila melanogaster[/i] Models for Alzheimer's Disease. / 2018 / PubMed / Full text
  • Sex and age interact to determine clinicopathologic differences in Alzheimer's disease. / 12.2018 / PubMed / Full text
  • Effects of a 3-Year Multi-Domain Intervention with or without Omega-3 Supplementation on Cognitive Functions in Older Subjects with Increased CAIDE Dementia Scores. / 2018 / PubMed / Full text
  • Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text
  • Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport. / 08.2018 / PubMed / Full text
  • Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases. / 01.04.2017 / PubMed / Full text
  • CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN. / 04.2017 / PubMed / Full text
  • Koolen-de Vries Syndrome: Clinical Report of an Adult and Literature Review. / 2016 / PubMed / Full text
  • Presymptomatic cognitive decline in familial frontotemporal dementia: A longitudinal study. / 26.07.2016 / PubMed / Full text
  • Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. / 24.02.2016 / PubMed / Full text
  • Cellular and molecular modifier pathways in tauopathies: the big picture from screening invertebrate models. / 04.2016 / PubMed / Full text
  • Drosophila models of Alzheimer's disease: advances, limits, and perspectives. / 2015 / PubMed / Full text
  • Association between MAPT haplotype and memory function in patients with Parkinson's disease and healthy aging individuals. / 03.2015 / PubMed / Full text

MBP[править]

  • Demyelination associated with chronic arsenic exposure in Wistar rats. / 15.04.2020 / PubMed / Full text
  • Natural killer cells as participants in pathogenesis of rat experimental autoimmune encephalomyelitis (EAE): lessons from research on rats with distinct age and strain. / 2019 / PubMed / Full text
  • Whey protein concentrate supplementation protects rat brain against aging-induced oxidative stress and neurodegeneration. / 05.2018 / PubMed / Full text
  • Strain specificities in age-related changes in mechanisms promoting and controlling rat spinal cord damage in experimental autoimmune encephalomyelitis. / 01.2018 / PubMed / Full text
  • Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils. / 09.2017 / PubMed / Full text
  • Schwann Cell Phenotype Changes in Aging Human Dental Pulp. / 03.2018 / PubMed / Full text
  • Blood pressure reactivity to mental stress is attenuated following resistance exercise in older hypertensive women. / 2017 / PubMed / Full text
  • Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss. / 08.05.2017 / PubMed / Full text
  • Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for CA1 neurons. / 05.2017 / PubMed / Full text
  • Postnatal alteration of monocarboxylate transporter 1 expression in the rat corpus callosum. / 04.05.2017 / PubMed / Full text
  • Bowel Preparation Is Associated with Reduced Morbidity in Elderly Patients Undergoing Elective Colectomy. / 02.2017 / PubMed / Full text
  • Myelin Basic Protein Regulates Primitive and Definitive Neural Stem Cell Proliferation from the Adult Spinal Cord. / 02.2017 / PubMed / Full text
  • Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset? / 12.08.2016 / PubMed / Full text
  • Generation of a LacZ reporter transgenic mouse line for the stereological analysis of oligodendrocyte loss in galactosylceramidase deficiency. / 12.2016 / PubMed / Full text
  • Loss of Hippocampal Oligodendrocytes Contributes to the Deficit of Contextual Fear Learning in Adult Rats Experiencing Early Bisphenol A Exposure. / 08.2017 / PubMed / Full text
  • Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4 T cells in aged rats. / 2015 / PubMed / Full text
  • Sleeve Gastrectomy Decreases Body Weight, Whole-Body Adiposity, and Blood Pressure Even in Aged Diet-Induced Obese Rats. / 07.2016 / PubMed / Full text
  • Classic and Golli Myelin Basic Protein have distinct developmental trajectories in human visual cortex. / 2015 / PubMed / Full text
  • Defective renal dopamine function and sodium-sensitive hypertension in adult ovariectomized Wistar rats: role of the cytochrome P-450 pathway. / 15.06.2015 / PubMed / Full text
  • White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke. / 10.2015 / PubMed / Full text
  • Age-related changes in spleen of Dark Agouti rats immunized for experimental autoimmune encephalomyelitis. / 15.01.2015 / PubMed / Full text
  • Phase separation of myelin sheath in Triton X-114 solution: predominant localization of the 21.5-kDa isoform of myelin basic protein in the lipid raft-associated domain. / 04.2014 / PubMed / Full text

PAH[править]

  • Changes in light absorption by brown carbon in soot particles due to heterogeneous ozone aging in a smog chamber. / 11.2020 / PubMed / Full text
  • Factors associated with pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc). / 09.2020 / PubMed / Full text
  • Potentially Avoidable Hospitalization among Long-Term Care Insurance Beneficiaries with Dementia. / 09.2020 / PubMed / Full text
  • Burden of disease at the same limit of exposure to airborne polycyclic aromatic hydrocarbons varies significantly across countries depending on the gap in longevity. / 30.09.2019 / PubMed / Full text
  • Converging Paths of Pulmonary Arterial Hypertension and Cellular Senescence. / 07.2019 / PubMed / Full text
  • Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells. / 15.12.2018 / PubMed / Full text
  • Exposure to Polycyclic Aromatic Hydrocarbons and Accelerated DNA Methylation Aging. / 06.2018 / PubMed / Full text
  • Arrhythmias in adult patients with congenital heart disease and pulmonary arterial hypertension. / 12.2018 / PubMed / Full text
  • Reduced bioavailability and plant uptake of polycyclic aromatic hydrocarbons from soil slurry amended with biochars pyrolyzed under various temperatures. / 06.2018 / PubMed / Full text
  • Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice. / 14.03.2018 / PubMed / Full text
  • Changes of total and freely dissolved polycyclic aromatic hydrocarbons and toxicity of biochars treated with various aging processes. / 06.2018 / PubMed / Full text
  • Bioaccessibility of PAHs and PAH derivatives in a fuel soot assessed by an in vitro digestive model with absorptive sink: Effects of aging the soot in a soil-water mixture. / 15.02.2018 / PubMed / Full text
  • Airborne polycyclic aromatic hydrocarbons trigger human skin cells aging through aryl hydrocarbon receptor. / 01.07.2017 / PubMed / Full text
  • DNA integrity-protecting and survival-promoting activity of serotonergic system in sturgeon juveniles and sazans. / 08.2017 / PubMed / Full text
  • Disruption of phenylalanine hydroxylase reduces adult lifespan and fecundity, and impairs embryonic development in parthenogenetic pea aphids. / 03.10.2016 / PubMed / Full text
  • Hepatic Responses of Juvenile Fundulus heteroclitus from Pollution-adapted and Nonadapted Populations Exposed to Elizabeth River Sediment Extract. / 07.2016 / PubMed / Full text
  • Non-muscle myosin light chain promotes endothelial progenitor cells senescence and dysfunction in pulmonary hypertensive rats through up-regulation of NADPH oxidase. / 15.03.2016 / PubMed / Full text
  • Maintaining lung health with longstanding HIV. / 02.2016 / PubMed / Full text
  • Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension. / 07.2015 / PubMed / Full text
  • Pulmonary arterial hypertension in rats due to age-related arginase activation in intermittent hypoxia. / 08.2015 / PubMed / Full text
  • Symptom Prevalence, Symptom Severity, and Health-Related Quality of Life Among Young, Middle, and Older Adults With Pulmonary Arterial Hypertension. / 04.2016 / PubMed / Full text
  • Plasma concentrations of tadalafil in children with pulmonary arterial hypertension. / 10.2014 / PubMed / Full text

TST[править]

  • H S Donors Reverse Age-Related Gastric Malfunction Impaired Due to Fructose-Induced Injury [i]via[/i] CBS, CSE, and TST Expression. / 2020 / PubMed / Full text
  • Adaptations in mechanical muscle function, muscle morphology, and aerobic power to high-intensity endurance training combined with either traditional or power strength training in older adults: a randomized clinical trial. / 05.2020 / PubMed / Full text
  • Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging. / 2019 / PubMed / Full text
  • Objective Sleep Duration in Older Adults: Results From The Irish Longitudinal Study on Ageing. / 01.2020 / PubMed / Full text
  • Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis. / 2019 / PubMed / Full text
  • Validity Evaluation of the Fitbit Charge2 and the Garmin vivosmart HR in Free-Living Environments in an Older Adult Cohort. / 19.06.2019 / PubMed / Full text
  • Paradoxical effect of testosterone supplementation therapy on cardiac ischemia/reperfusion injury in aged rats. / 07.2019 / PubMed / Full text
  • Sleep Disturbances and Risk of Hospitalization and Inpatient Days Among Older Women. / 01.04.2017 / PubMed / Full text
  • Relationships between [i]FTO[/i] rs9939609, [i]MC4R[/i] rs17782313, and [i]PPARγ[/i] rs1801282 polymorphisms and the occurrence of selected metabolic and hormonal disorders in middle-aged and elderly men - a preliminary study. / 2016 / PubMed / Full text
  • Rest-Activity Patterns in Older Adults with Heart Failure and Healthy Older Adults. / 01.2017 / PubMed / Full text
  • The impact of BCG vaccination on tuberculin skin test responses in children is age dependent: evidence to be considered when screening children for tuberculosis infection. / 10.2016 / PubMed / Full text
  • The relation between polysomnography and subjective sleep and its dependence on age - poor sleep may become good sleep. / 10.2016 / PubMed / Full text
  • Association between physiological falls risk and physical performance tests among community-dwelling older adults. / 2015 / PubMed / Full text
  • Anthropometric reference data for elderly Swedes and its disease-related pattern. / 09.2015 / PubMed / Full text
  • Impact of maternal melatonin suppression on forced swim and tail suspension behavioral despair tests in adult offspring. / 04-06.2015 / PubMed / Full text
  • Controversies in testosterone supplementation therapy. / 03-04.2015 / PubMed / Full text
  • Diagnosis and management of testosterone deficiency. / 03-04.2015 / PubMed / Full text
  • Testosterone replacement therapy: who to evaluate, what to use, how to follow, and who is at risk? / 12.2014 / PubMed / Full text
  • An Overview of Testosterone Therapy. / 01.2016 / PubMed / Full text
  • Associations of objectively and subjectively measured sleep quality with subsequent cognitive decline in older community-dwelling men: the MrOS sleep study. / 01.04.2014 / PubMed / Full text
  • Chronotype, bed timing and total sleep time in seniors. / 06.2014 / PubMed / Full text
  • Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus. / 01.01.2014 / PubMed / Full text

BAX[править]

  • Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-X -BAX interaction. / 10.2020 / PubMed / Full text
  • CREB Signaling Mediates Dose-Dependent Radiation Response in the Murine Hippocampus Two Years after Total Body Exposure. / 03.01.2020 / PubMed / Full text
  • Reduced sucrose nonfermenting AMPK-related kinase (SNARK) activity aggravates cancer-induced skeletal muscle wasting. / 09.2019 / PubMed / Full text
  • Modulated electro-hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro. / 08.2019 / PubMed / Full text
  • The Clearance Effect of Tetrahedral DNA Nanostructures on Senescent Human Dermal Fibroblasts. / 16.01.2019 / PubMed / Full text
  • Premature placental aging in term small-for-gestational-age and growth-restricted fetuses. / 05.2019 / PubMed / Full text
  • Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training. / 01.10.2018 / PubMed / Full text
  • Xanthohumol exerts protective effects in liver alterations associated with aging. / 03.2019 / PubMed / Full text
  • Protective effect of xanthohumol against age-related brain damage. / 11.2017 / PubMed / Full text
  • [Inula Britannica flower total flavonoids reduces the apoptosis of aging bone marrow mesenchymal stem cells by anti-oxidation]. / 05.2017 / PubMed
  • Hilar granule cells of the mouse dentate gyrus: effects of age, septotemporal location, strain, and selective deletion of the proapoptotic gene BAX. / 09.2017 / PubMed / Full text
  • p16 enhances the transcriptional and the apoptotic functions of p53 through DNA-dependent interaction. / 07.2017 / PubMed / Full text
  • Protective effects of high Tryptophan diet on aging-induced passive avoidance impairment and hippocampal apoptosis. / 01.2017 / PubMed / Full text
  • Mechanisms of Heshouwuyin in regulating apoptosis of testicular cells in aging rats through mitochondrial pathway. / 01.09.2016 / PubMed / Full text
  • Response of BAX, Bcl-2 Proteins, and SIRT1/PGC-1α mRNA Expression to 8-Week Treadmill Running in the Aging Rat Skeletal Muscle. / 2016 / PubMed / Full text
  • Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. / 10.2016 / PubMed / Full text
  • Apoptosis in young and old denervated rat skeletal muscle. / 02.2017 / PubMed / Full text
  • Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system. / 07.2016 / PubMed / Full text
  • Melatonin decreases the expression of inflammation and apoptosis markers in the lung of a senescence-accelerated mice model. / 03.2016 / PubMed / Full text
  • Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats. / 2015 / PubMed / Full text
  • The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats. / 07.2015 / PubMed / Full text

CCR2[править]

  • Hip Fracture Leads to Transitory Immune Imprint in Older Patients. / 2020 / PubMed / Full text
  • The CC-chemokine receptor 2 is involved in the control of ovarian folliculogenesis and fertility lifespan in mice. / 09.2020 / PubMed / Full text
  • Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity. / 08.2020 / PubMed / Full text
  • Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction. / 26.03.2020 / PubMed / Full text
  • Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by CCR2. / 02.2020 / PubMed / Full text
  • Klotho-mediated targeting of CCL2 suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments. / 11.2019 / PubMed / Full text
  • Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90   subset. / 10.2019 / PubMed / Full text
  • Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells. / 14.11.2018 / PubMed / Full text
  • Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain. / 30.05.2018 / PubMed / Full text
  • Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging. / 05.2018 / PubMed / Full text
  • Inhibition of Radiation-Induced Ccl2 Signaling Protects Lungs from Vascular Dysfunction and Endothelial Cell Loss. / 10.01.2019 / PubMed / Full text
  • Attenuated Macrophage Infiltration in Glomeruli of Aged Mice Resulting in Ameliorated Kidney Injury in Nephrotoxic Serum Nephritis. / 10.08.2018 / PubMed / Full text
  • Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression. / 10.10.2016 / PubMed / Full text
  • Absence of CCR2 results in an inflammaging environment in young mice with age-independent impairments in muscle regeneration. / 11.2016 / PubMed / Full text
  • Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities. / 13.06.2016 / PubMed / Full text
  • Age exacerbates the CCR2/5-mediated neuroinflammatory response to traumatic brain injury. / 18.04.2016 / PubMed / Full text
  • Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging. / 04.2016 / PubMed / Full text
  • Alterations in Monocyte Phenotypes and Functions after a Hip Fracture in Elderly Individuals: A 6-Month Longitudinal Study. / 2016 / PubMed / Full text
  • TNF Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity. / 01.2016 / PubMed / Full text
  • Senescent dermal fibroblasts enhance stem cell migration through CCL2/CCR2 axis. / 07.2015 / PubMed / Full text
  • Differential expression of monocyte surface markers among TB patients with diabetes co-morbidity. / 12.2013 / PubMed / Full text

CD40[править]

  • The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy. / 2018 / PubMed / Full text
  • Age-Related Changes on CD40 Promotor Methylation and Immune Gene Expressions in Thymus of Chicken. / 2018 / PubMed / Full text
  • Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia. / 2018 / PubMed / Full text
  • One-Year Consumption of a Mediterranean-Like Dietary Pattern With Vitamin D3 Supplements Induced Small Scale but Extensive Changes of Immune Cell Phenotype, Co-receptor Expression and Innate Immune Responses in Healthy Elderly Subjects: Results From the United Kingdom Arm of the NU-AGE Trial. / 2018 / PubMed / Full text
  • Membrane-Bound CD40L Promotes Senescence and Initiates Senescence-Associated Secretory Phenotype via NF-κB Activation in Lung Adenocarcinoma. / 2018 / PubMed / Full text
  • Effects of Immunosenescence on the Lower Expression of Surface Molecules in Neutrophils and Lymphocytes. / 2018 / PubMed / Full text
  • Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice. / 2018 / PubMed / Full text
  • Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation. / 2018 / PubMed / Full text
  • C-Reactive Protein Impairs Dendritic Cell Development, Maturation, and Function: Implications for Peripheral Tolerance. / 2018 / PubMed / Full text
  • Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin-utrophin double knockout mice. / 12.2017 / PubMed / Full text
  • Age-Associated B Cells Express a Diverse Repertoire of V and Vκ Genes with Somatic Hypermutation. / 01.03.2017 / PubMed / Full text
  • Autoimmune manifestations in aged mice arise from early-life immune dysregulation. / 19.10.2016 / PubMed / Full text
  • The age-related neuroinflammatory environment promotes macrophage activation, which negatively impacts synaptic function. / 07.2016 / PubMed / Full text
  • Combinatorial approach to cancer immunotherapy: strength in numbers. / 08.2016 / PubMed / Full text
  • Human mesothelioma induces defects in dendritic cell numbers and antigen-processing function which predict survival outcomes. / 02.2016 / PubMed / Full text
  • Skewing of peritoneal resident macrophages toward M1-like is involved in enhancement of inflammatory responses induced by secondary necrotic neutrophils in aged mice. / 06-07.2016 / PubMed / Full text
  • Blood-borne biomarkers of mortality risk: systematic review of cohort studies. / 2015 / PubMed / Full text
  • Age-associated modifications of intestinal permeability and innate immunity in human small intestine. / 10.2015 / PubMed / Full text
  • Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarction. / 15.02.2015 / PubMed / Full text
  • Maturation of innate responses to mycobacteria over the first nine months of life. / 15.05.2014 / PubMed / Full text
  • IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice. / 06.2014 / PubMed / Full text

ELOVL2[править]

  • ELOVL2: Not just a biomarker of aging. / 2020 / PubMed / Full text
  • The lipid elongation enzyme ELOVL2 is a molecular regulator of aging in the retina. / 02.2020 / PubMed / Full text
  • Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts. / 10.2019 / PubMed / Full text
  • Cell and tissue type independent age-associated DNA methylation changes are not rare but common. / 27.11.2018 / PubMed / Full text
  • DNA methylation of the ELOVL2, FHL2, KLF14, C1orf132/MIR29B2C, and TRIM59 genes for age prediction from blood, saliva, and buccal swab samples. / 01.2019 / PubMed / Full text
  • Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing. / 09.2018 / PubMed / Full text
  • Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception. / 30.05.2018 / PubMed / Full text
  • DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird. / 2017 / PubMed / Full text
  • Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text
  • DNA methylation in ELOVL2 and C1orf132 correctly predicted chronological age of individuals from three disease groups. / 01.2018 / PubMed / Full text
  • Independent validation of DNA-based approaches for age prediction in blood. / 07.2017 / PubMed / Full text
  • Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines. / 12.05.2017 / PubMed / Full text
  • Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process. / 01.08.2017 / PubMed / Full text
  • Donor age and C1orf132/MIR29B2C determine age-related methylation signature of blood after allogeneic hematopoietic stem cell transplantation. / 2016 / PubMed / Full text
  • Forensic age prediction for dead or living samples by use of methylation-sensitive high resolution melting. / 07.2016 / PubMed / Full text
  • Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system. / 09.2016 / PubMed / Full text
  • Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model. / 03.2016 / PubMed / Full text
  • Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study. / 09.02.2016 / PubMed / Full text
  • Improved age determination of blood and teeth samples using a selected set of DNA methylation markers. / 2015 / PubMed / Full text
  • Development of a forensically useful age prediction method based on DNA methylation analysis. / 07.2015 / PubMed / Full text
  • Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs. / 06.2014 / PubMed / Full text

REST[править]

  • [Brain and Neuronal Aging: Aged Brain Controls via Gene Expression Fidelity and Master Regulatory Factors]. / 2020 / PubMed / Full text
  • Effect of 9 - PAHSA on cognitive dysfunction in diabetic mice and its possible mechanism. / 09.04.2020 / PubMed / Full text
  • Increased REST to Optimize Life Span? / 12.2019 / PubMed / Full text
  • Cardiac baroreflex hysteresis is one of the determinants of the heart period variability asymmetry. / 01.10.2019 / PubMed / Full text
  • Pterostilbene Improves Cognitive Performance in Aged Rats: An in Vivo Study. / 2019 / PubMed / Full text
  • Comparison between probabilistic and Wiener-Granger causality in assessing modifications of the cardiac baroreflex control with age. / 22.10.2018 / PubMed / Full text
  • Fast-Evolving Human-Specific Neural Enhancers Are Associated with Aging-Related Diseases. / 23.05.2018 / PubMed / Full text
  • Influence of age and gender on the phase and strength of the relation between heart period and systolic blood pressure spontaneous fluctuations. / 01.03.2018 / PubMed / Full text
  • Genetic Biomarkers on Age-Related Cognitive Decline. / 2017 / PubMed / Full text
  • MicroRNA Expression Analysis of Centenarians and Rheumatoid Arthritis Patients Reveals a Common Expression Pattern. / 2017 / PubMed / Full text
  • The rs1277306 Variant of the REST Gene Confers Susceptibility to Cognitive Aging in an Elderly Taiwanese Population. / 2017 / PubMed / Full text
  • Assessing the evolution of redundancy/synergy of spontaneous variability regulation with age. / 05.2017 / PubMed / Full text
  • Sixty years old is the breakpoint of human frontal cortex aging. / 02.2017 / PubMed / Full text
  • Is senescence-associated β-galactosidase a marker of neuronal senescence? / 06.12.2016 / PubMed / Full text
  • Running for REST: Physical activity attenuates neuroinflammation in the hippocampus of aged mice. / 03.2017 / PubMed / Full text
  • Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models. / 30.03.2017 / PubMed / Full text
  • A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM-p53 signaling. / 01.02.2016 / PubMed / Full text
  • An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging. / 02.2015 / PubMed / Full text
  • MicroRNA-9 controls dendritic development by targeting REST. / 18.11.2014 / PubMed / Full text
  • Rcor2 underexpression in senescent mice: a target for inflammaging? / 23.07.2014 / PubMed / Full text
  • REST and stress resistance in ageing and Alzheimer's disease. / 27.03.2014 / PubMed / Full text

SIRT7[править]

  • SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer. / 07.2020 / PubMed / Full text
  • Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri. / 09.2019 / PubMed / Full text
  • Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7. / 2018 / PubMed / Full text
  • The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability. / 13.07.2018 / PubMed / Full text
  • Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas. / 08.2018 / PubMed / Full text
  • Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. / 08.10.2018 / PubMed / Full text
  • The effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome. / 31.07.2017 / PubMed / Full text
  • Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. / 01.06.2017 / PubMed / Full text
  • The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging. / 12.2016 / PubMed / Full text
  • Molecular, Cellular, and Physiological Characterization of Sirtuin 7 (SIRT7). / 2016 / PubMed / Full text
  • miR-152 induces human dental pulp stem cell senescence by inhibiting SIRT7 expression. / 04.2016 / PubMed / Full text
  • Sirtuins, Cell Senescence, and Vascular Aging. / 05.2016 / PubMed / Full text
  • The expression levels of the sirtuins in patients with BCC. / 05.2016 / PubMed / Full text
  • Age-Related Changes in Sirtuin 7 Expression in Calorie-Restricted and Refed Rats. / 2016 / PubMed / Full text
  • Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum. / 11.2015 / PubMed / Full text
  • Novel protein-protein interactions of TPPII, p53, and SIRT7. / 11.2015 / PubMed / Full text
  • Differential expression of sirtuins in the aging rat brain. / 2015 / PubMed / Full text
  • Stressed SIRT7: facing a crossroad of senescence and immortality. / 06.2015 / PubMed / Full text
  • Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response. / 01.02.2015 / PubMed / Full text
  • A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function. / 04.11.2014 / PubMed / Full text
  • Comparative interactomes of SIRT6 and SIRT7: Implication of functional links to aging. / 07.2014 / PubMed / Full text

TEC[править]

  • Vestibular function and cortical and sub-cortical alterations in an aging population. / 08.2020 / PubMed / Full text
  • Metabolic Flexibility and Innate Immunity in Renal Ischemia Reperfusion Injury: The Fine Balance Between Adaptive Repair and Tissue Degeneration. / 2020 / PubMed / Full text
  • Postnatal Involution and Counter-Involution of the Thymus. / 2020 / PubMed / Full text
  • Gender Disparity Impacts on Thymus Aging and LHRH Receptor Antagonist-Induced Thymic Reconstitution Following Chemotherapeutic Damage. / 2020 / PubMed / Full text
  • Clonogenic Culture of Mouse Thymic Epithelial Cells. / 2019 / PubMed / Full text
  • TREM1/3 Deficiency Impairs Tissue Repair After Acute Kidney Injury and Mitochondrial Metabolic Flexibility in Tubular Epithelial Cells. / 2019 / PubMed / Full text
  • Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging. / 25.06.2019 / PubMed / Full text
  • Transgenic Exosomes for Thymus Regeneration. / 2019 / PubMed / Full text
  • Cell-type-specific role of lamin-B1 in thymus development and its inflammation-driven reduction in thymus aging. / 08.2019 / PubMed / Full text
  • Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces. / 03.2019 / PubMed / Full text
  • Epithelial innate immunity mediates tubular cell senescence after kidney injury. / 24.01.2019 / PubMed / Full text
  • Thymic Epithelial Cell Support of Thymopoiesis Does Not Require [i]Klotho[/i]. / 01.12.2018 / PubMed / Full text
  • MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors. / 2017 / PubMed / Full text
  • A Fine-Tune Role of Mir-125a-5p on [i]Foxn1[/i] During Age-Associated Changes in the Thymus. / 05.2017 / PubMed / Full text
  • Mechanisms and kinetics of proliferation and fibrosis development in a mouse model of thyrocyte hyperplasia. / 06-07.2016 / PubMed / Full text
  • Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution. / 2016 / PubMed / Full text
  • Foxn1 Protein Expression in the Developing, Aging, and Regenerating Thymus. / 15.12.2015 / PubMed / Full text
  • Young, proliferative thymic epithelial cells engraft and function in aging thymuses. / 15.05.2015 / PubMed / Full text
  • Regeneration of the aged thymus by a single transcription factor. / 04.2014 / PubMed / Full text
  • Meis1 is required for the maintenance of postnatal thymic epithelial cells. / 2014 / PubMed / Full text
  • Identification of novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6. / 2014 / PubMed / Full text

C6[править]

  • Evolution of the Aroma of Treixadura Wines during Bottle Aging. / 08.10.2020 / PubMed / Full text
  • D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway. / 29.09.2020 / PubMed / Full text
  • Alcohol Extracts From [i]Ganoderma lucidum[/i] Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents. / 2019 / PubMed / Full text
  • Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. / 2018 / PubMed / Full text
  • Population-Stratified Analysis of Bone Mineral Density Distribution in Cervical and Lumbar Vertebrae of Chinese from Quantitative Computed Tomography. / 09-10.2016 / PubMed / Full text
  • Demographic aspects in cervical vertebral bodies' size and shape (C3-C7): a skeletal study. / 01.2017 / PubMed / Full text
  • Neonatal Benzo[a]pyrene Exposure Induces Oxidative Stress and DNA Damage Causing Neurobehavioural Changes during the Early Adolescence Period in Rats. / 2016 / PubMed / Full text
  • Variations in Occipitocervical and Cervicothoracic Alignment Parameters Based on Age: A Prospective Study of Asymptomatic Volunteers Using Full-Body Radiographs. / 01.12.2016 / PubMed / Full text
  • Age-related brain atrophy may be mitigated by internal jugular vein enlargement in male individuals without neurologic disease. / 03.2017 / PubMed / Full text
  • The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis. / 2016 / PubMed / Full text
  • Depletion of B cell CLL/Lymphoma 11B Gene Expression Represses Glioma Cell Growth. / 08.2016 / PubMed / Full text
  • Are the standard parameters of cervical spine alignment and range of motion related to age, sex, and cervical disc degeneration? / 09.2015 / PubMed / Full text
  • Age-related morphologic changes of the vertebral artery in the transverse process. Analysis by multidetector computed tomography angiography. / 01.09.2015 / PubMed / Full text
  • Role of the serotonin transporter gene locus in the response to SSRI treatment of major depressive disorder in late life. / 05.2015 / PubMed / Full text
  • The Impact of Genetics on Physical Resilience and Successful Aging. / 09.2015 / PubMed / Full text
  • Intake of low-dose leucine-rich essential amino acids stimulates muscle anabolism equivalently to bolus whey protein in older women at rest and after exercise. / 15.06.2015 / PubMed / Full text
  • Non-sirtuin histone deacetylases in the control of cardiac aging. / 06.2015 / PubMed / Full text
  • Engineering temporal accumulation of a low recalcitrance polysaccharide leads to increased C6 sugar content in plant cell walls. / 09.2015 / PubMed / Full text
  • The effects of age on the morphometry of the cervical spinal cord and spinal column in adult rats: an MRI-based study. / 10.2014 / PubMed / Full text
  • Spontaneous age-related cervical disc degeneration in the sand rat. / 06.2014 / PubMed / Full text

C7[править]

  • The Vertebral Artery Convergence to the Cervical Spine in Elders. / 30.09.2019 / PubMed / Full text
  • Age-related Changes in Cervical Sagittal Alignment: A Radiographic Analysis. / 01.10.2019 / PubMed / Full text
  • Early Intravenous Infusion of Mesenchymal Stromal Cells Exerts a Tissue Source Age-Dependent Beneficial Effect on Neurovascular Integrity and Neurobehavioral Recovery After Traumatic Cervical Spinal Cord Injury. / 07.2019 / PubMed / Full text
  • Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. / 2018 / PubMed / Full text
  • Twenty-year Longitudinal Follow-up MRI Study of Asymptomatic Volunteers: The Impact of Cervical Alignment on Disk Degeneration. / 12.2018 / PubMed / Full text
  • The change of cervical spine alignment along with aging in asymptomatic population: a preliminary analysis. / 09.2017 / PubMed / Full text
  • Lumbar Retrolisthesis in Aging Spine: What are the Associated Factors? / 07.2017 / PubMed / Full text
  • Three types of sagittal alignment regarding compensation in asymptomatic adults: the contribution of the spine and lower limbs. / 02.2018 / PubMed / Full text
  • Age-related variations in global spinal alignment and sagittal balance in asymptomatic Japanese adults. / 05.2017 / PubMed / Full text
  • Standing sagittal alignment of the whole axial skeleton with reference to the gravity line in humans. / 05.2017 / PubMed / Full text
  • Population-Stratified Analysis of Bone Mineral Density Distribution in Cervical and Lumbar Vertebrae of Chinese from Quantitative Computed Tomography. / 09-10.2016 / PubMed / Full text
  • Demographic aspects in cervical vertebral bodies' size and shape (C3-C7): a skeletal study. / 01.2017 / PubMed / Full text
  • Prediction of Cervical Endplate Size: One Size Does Not Fit All. / 01.05.2016 / PubMed / Full text
  • Variations in Occipitocervical and Cervicothoracic Alignment Parameters Based on Age: A Prospective Study of Asymptomatic Volunteers Using Full-Body Radiographs. / 01.12.2016 / PubMed / Full text
  • Age-related brain atrophy may be mitigated by internal jugular vein enlargement in male individuals without neurologic disease. / 03.2017 / PubMed / Full text
  • The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis. / 2016 / PubMed / Full text
  • Signal intensity loss of the intervertebral discs in the cervical spine of young patients on fluid sensitive sequences. / 03.2016 / PubMed / Full text
  • The Cervical Spinal Canal Tapers Differently in Patients with Chiari I with and without Syringomyelia. / 04.2016 / PubMed / Full text
  • Corticospinal tract development and spinal cord innervation differ between cervical and lumbar targets. / 21.01.2015 / PubMed / Full text
  • Spontaneous age-related cervical disc degeneration in the sand rat. / 06.2014 / PubMed / Full text

CDKN2A[править]

  • Association between Nrf2 and CDKN2A expression in patients with end-stage renal disease: a pilot study. / 13.07.2020 / PubMed / Full text
  • Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts. / 12.2019 / PubMed / Full text
  • Analysis of the putative tumor suppressor gene cdkn2ab in pigment cells and melanoma of Xiphophorus and medaka. / 03.2019 / PubMed / Full text
  • In vitro behavior and UV response of melanocytes derived from carriers of [[CDKN2A]] mutations and MC1R variants. / 03.2019 / PubMed / Full text
  • Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging. / 07.2018 / PubMed / Full text
  • Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16 inactivation. / 26.02.2018 / PubMed / Full text
  • Cellular aging dynamics after acute malaria infection: A 12-month longitudinal study. / 02.2018 / PubMed / Full text
  • ARID1A suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[CDKN2A]] regulatory axis. / 18.11.2017 / PubMed / Full text
  • Cellular Senescence in Mouse Hippocampus After Irradiation and the Role of p53 and p21. / 01.04.2017 / PubMed / Full text
  • Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome. / 06.2017 / PubMed / Full text
  • ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A. / 24.03.2017 / PubMed / Full text
  • Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing. / 14.02.2017 / PubMed / Full text
  • Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus. / 18.05.2016 / PubMed / Full text
  • Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts. / 11-12.2015 / PubMed / Full text
  • Alterations of telomere length and DNA methylation in hairdressers: A cross-sectional study. / 03.2016 / PubMed / Full text
  • Genetics of melanoma progression: the rise and fall of cell senescence. / 03.2016 / PubMed / Full text
  • Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. / 02.11.2015 / PubMed / Full text
  • Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium. / 06.2015 / PubMed / Full text
  • Y-27632, a ROCK inhibitor, delays senescence of putative murine salivary gland stem cells in culture. / 06.2015 / PubMed / Full text
  • Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex. / 29.05.2014 / PubMed / Full text

CXCL1[править]

  • Contusion spinal cord injury upregulates p53 protein expression in rat soleus muscle at multiple timepoints but not key senescence cytokines. / 02.2020 / PubMed / Full text
  • Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy. / 2019 / PubMed / Full text
  • Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression. / 2019 / PubMed / Full text
  • Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. / 07.2019 / PubMed / Full text
  • Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality. / 03.2019 / PubMed / Full text
  • Prophylactic Palmitoylethanolamide Prolongs Survival and Decreases Detrimental Inflammation in Aged Mice With Bacterial Meningitis. / 2018 / PubMed / Full text
  • The Role of Pulmonary and Systemic Immunosenescence in Acute Lung Injury. / 08.2018 / PubMed / Full text
  • Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age. / 09.2018 / PubMed / Full text
  • Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice. / 2018 / PubMed / Full text
  • Infiltrating macrophages contribute to age-related neuroinflammation in C57/BL6 mice. / 07.2018 / PubMed / Full text
  • Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles. / 05.2018 / PubMed / Full text
  • Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A receptor. / 18.10.2017 / PubMed / Full text
  • IFN-γ induces senescence-like characteristics in mouse bone marrow mesenchymal stem cells. / 03-04.2017 / PubMed / Full text
  • Methyl caffeate and some plant constituents inhibit age-related inflammation: effects on senescence-associated secretory phenotype (SASP) formation. / 04.2017 / PubMed / Full text
  • Adiponectin induces CXCL1 secretion from cancer cells and promotes tumor angiogenesis by inducing stromal fibroblast senescence. / 11.2016 / PubMed / Full text
  • Senescent peritoneal mesothelium induces a pro-angiogenic phenotype in ovarian cancer cells in vitro and in a mouse xenograft model in vivo. / 01.2016 / PubMed / Full text
  • CXCL1 Triggers Caspase-3 Dependent Tau Cleavage in Long-Term Neuronal Cultures and in the Hippocampus of Aged Mice: Implications in Alzheimer's Disease. / 2015 / PubMed / Full text
  • Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts. / 15.08.2015 / PubMed / Full text
  • Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. / 2015 / PubMed / Full text
  • Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. / 06.2015 / PubMed / Full text

CXCR4[править]

  • Aging-Related Reduced Expression of CXCR4 on Bone Marrow Mesenchymal Stromal Cells Contributes to Hematopoietic Stem and Progenitor Cell Defects. / 08.2020 / PubMed / Full text
  • Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway. / 09.2020 / PubMed / Full text
  • Stromal Cell-Derived Factor 1 Protects Brain Vascular Endothelial Cells from Radiation-Induced Brain Damage. / 10.10.2019 / PubMed / Full text
  • A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. / 19.02.2019 / PubMed / Full text
  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
  • Reducing CXCR4 Resulted in Impairing Proliferation and Promoting Aging. / 2018 / PubMed / Full text
  • Targeting junctional adhesion molecule-C ameliorates sepsis-induced acute lung injury by decreasing CXCR4 aged neutrophils. / 12.2018 / PubMed / Full text
  • Tumor microenvironment in functional adrenocortical adenomas: immune cell infiltration in cortisol-producing adrenocortical adenoma. / 07.2018 / PubMed / Full text
  • Lower resting and exercise-induced circulating angiogenic progenitors and angiogenic T cells in older men. / 01.03.2018 / PubMed / Full text
  • Adipose-Derived Mesenchymal Stem Cells from the Elderly Exhibit Decreased Migration and Differentiation Abilities with Senescent Properties. / 09.2017 / PubMed / Full text
  • Conversion of adult endothelium to immunocompetent haematopoietic stem cells. / 25.05.2017 / PubMed / Full text
  • Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells. / 01.09.2017 / PubMed / Full text
  • The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy. / 22.01.2017 / PubMed / Full text
  • Age and Human Regenerative Capacity Impact of Cardiovascular Risk Factors. / 16.09.2016 / PubMed / Full text
  • Effect of age on expression of spermatogonial markers in bovine testis and isolated cells. / 07.2016 / PubMed / Full text
  • Increased susceptibility of CD4 T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels. / 09.10.2015 / PubMed / Full text
  • A single fas gene mutation changes lupus onset, severity, location, and molecular abnormalities in mice. / 2015 / PubMed / Full text
  • Caloric restriction and the adipokine leptin alter the SDF-1 signaling axis in bone marrow and in bone marrow derived mesenchymal stem cells. / 15.07.2015 / PubMed / Full text
  • CXCR4 blockade induces atherosclerosis by affecting neutrophil function. / 09.2014 / PubMed / Full text
  • Trafficking phenotype and production of granzyme B by double negative B cells (IgG( )IgD(-)CD27(-)) in the elderly. / 06.2014 / PubMed / Full text

ERG[править]

  • Effect of age and sex on neurodevelopment and neurodegeneration in the healthy eye: Longitudinal functional and structural study in the Long-Evans rat. / 11.2020 / PubMed / Full text
  • Mice With a Combined Deficiency of Superoxide Dismutase 1 (Sod1), DJ-1 (Park7), and Parkin (Prkn) Develop Spontaneous Retinal Degeneration With Aging. / 03.09.2019 / PubMed / Full text
  • Test-retest repeatability of the pattern electroretinogram and flicker electroretinogram. / 12.2019 / PubMed / Full text
  • Regeneration of Dopaminergic Neurons in Adult Zebrafish Depends on Immune System Activation and Differs for Distinct Populations. / 12.06.2019 / PubMed / Full text
  • Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. / 01.05.2019 / PubMed / Full text
  • Further Characterization of the Predominant Inner Retinal Degeneration of Aging Cln3 Knock-In Mice. / 2018 / PubMed / Full text
  • Two novel forms of ERG oscillation in Drosophila: age and activity dependence. / 03-06.2018 / PubMed / Full text
  • Loss of XBP1 accelerates age-related decline in retinal function and neurodegeneration. / 04.04.2018 / PubMed / Full text
  • The Complement System Is Critical in Maintaining Retinal Integrity during Aging. / 2018 / PubMed / Full text
  • EDI OCT evaluation of choroidal thickness in Stargardt disease. / 2018 / PubMed / Full text
  • Intensity response function of the photopic negative response (PhNR): effect of age and test-retest reliability. / 08.2017 / PubMed / Full text
  • Nonamyloidogenic processing of amyloid beta precursor protein is associated with retinal function improvement in aging male APP /PS1ΔE9 mice. / 05.2017 / PubMed / Full text
  • Absence of DJ-1 causes age-related retinal abnormalities in association with increased oxidative stress. / 03.2017 / PubMed / Full text
  • Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. / 23.06.2016 / PubMed / Full text
  • Age-related change in fast adaptation mechanisms measured with the scotopic full-field ERG. / 06.2016 / PubMed / Full text
  • Relation of BAALC and ERG Gene Expression with Overall Survival in Acute Myeloid Leukemia Cases. / 2015 / PubMed / Full text
  • Differences in Retinal Structure and Function between Aging Male and Female Sprague-Dawley Rats are Strongly Influenced by the Estrus Cycle. / 2015 / PubMed / Full text
  • Lack of Acid Sphingomyelinase Induces Age-Related Retinal Degeneration. / 2015 / PubMed / Full text
  • Changes in rod and cone-driven oscillatory potentials in the aging human retina. / 17.07.2014 / PubMed / Full text
  • The effect of ageing on ocular blood flow, oxygen tension and retinal function during and after intraocular pressure elevation. / 2014 / PubMed / Full text

FES[править]

  • An outpatient Tai Chi program: Effects on veterans' functional outcomes. / 26.11.2020 / PubMed / Full text
  • Gait Function in Adults Aged 50 Years and Older With Spina Bifida. / 07.11.2020 / PubMed / Full text
  • A Single Question as a Screening Tool to Assess Fear of Falling in Young-Old Community-Dwelling Persons. / 09.2020 / PubMed / Full text
  • Fall-related efficacy is a useful and independent index to detect fall risk in Japanese community-dwelling older people: a 1-year longitudinal study. / 29.10.2019 / PubMed / Full text
  • Investigating Changes in Real-time Conscious Postural Processing by Older Adults during Different Stance Positions Using Electroencephalography Coherence. / 10-12.2019 / PubMed / Full text
  • Effectiveness of Daily Use of Bilateral Custom-Made Ankle-Foot Orthoses on Balance, Fear of Falling, and Physical Activity in Older Adults: A Randomized Controlled Trial. / 2019 / PubMed / Full text
  • Decline in sensorimotor systems explains reduced falls self-efficacy. / 10.2018 / PubMed / Full text
  • Fear of Falling in Older Adults with Diabetes Mellitus: The IMIAS Study. / 09.2018 / PubMed / Full text
  • Cross-cultural adaptation and measurement properties testing of the Iconographical Falls Efficacy Scale (Icon-FES). / 07-08.2018 / PubMed / Full text
  • Binocular Vision Disorders and Visual Attention: Associations With Balance and Mobility in Older Adults. / 01.04.2018 / PubMed / Full text
  • Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS. / 25.05.2017 / PubMed / Full text
  • FES in Europe and Beyond: Current Translational Research. / 15.09.2016 / PubMed / Full text
  • Use it or Lose It: Tonic Activity of Slow Motoneurons Promotes Their Survival and Preferentially Increases Slow Fiber-Type Groupings in Muscles of Old Lifelong Recreational Sportsmen. / 15.09.2016 / PubMed / Full text
  • Recovery from muscle weakness by exercise and FES: lessons from Masters, active or sedentary seniors and SCI patients. / 08.2017 / PubMed / Full text
  • Biology of Muscle Atrophy and of its Recovery by FES in Aging and Mobility Impairments: Roots and By-Products. / 24.08.2015 / PubMed / Full text
  • Balance Disorders in the Elderly: Does Instability Increase Over Time? / 07.2016 / PubMed / Full text
  • Age group classification and gender detection based on forced expiratory spirometry. / 08.2015 / PubMed / Full text
  • Is there a relationship between short FES-I test scores and objective assessment of balance in the older people with age-induced instability? / 01-02.2016 / PubMed / Full text
  • Age-associated declines in muscle mass, strength, power, and physical performance: impact on fear of falling and quality of life. / 02.2016 / PubMed / Full text
  • Effects of functional electric stimulation cycle ergometry training on lower limb musculature in acute sci individuals. / 01.09.2005 / PubMed / Full text

JAK2[править]

  • Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity. / 2020 / PubMed / Full text
  • Quercetin Directly Targets JAK2 and PKCδ and Prevents UV-Induced Photoaging in Human Skin. / 23.10.2019 / PubMed / Full text
  • [Red blood cell lifespan detected by endogenous carbon monoxide breath test in patients with polycythemia vera]. / 01.10.2019 / PubMed / Full text
  • Roles of JAK2 in Aging, Inflammation, Hematopoiesis and Malignant Transformation. / 08.08.2019 / PubMed / Full text
  • The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver. / 04.2019 / PubMed / Full text
  • Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development. / 06.2019 / PubMed / Full text
  • Distinctive features of polycythaemia vera in New Zealand Polynesians. / 21.09.2018 / PubMed
  • Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. / 04.2018 / PubMed / Full text
  • Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender. / 10.2017 / PubMed / Full text
  • Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment. / 23.05.2017 / PubMed / Full text
  • The Dyslexia-susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling. / 01.03.2017 / PubMed / Full text
  • JAK-STAT signaling mediates the senescence of bone marrow-mesenchymal stem cells from systemic lupus erythematosus patients. / 01.03.2017 / PubMed / Full text
  • Oxidative stress induces the decline of brain EPO expression in aging rats. / 10.2016 / PubMed / Full text
  • Scribble is required for pregnancy-induced alveologenesis in the adult mammary gland. / 15.06.2016 / PubMed / Full text
  • Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression. / 03.05.2016 / PubMed / Full text
  • Exogenous H2S contributes to recovery of ischemic post-conditioning-induced cardioprotection by decrease of ROS level via down-regulation of NF-κB and JAK2-STAT3 pathways in the aging cardiomyocytes. / 2016 / PubMed / Full text
  • Correlation Analysis Between Expression Levels of Hepatic Growth Hormone Receptor, Janus Kinase 2, Insulin-Like Growth Factor-I Genes and Dwarfism Phenotype in Bama Minipig. / 02.2015 / PubMed / Full text
  • Emerging drugs for the treatment of myelofibrosis. / 2015 / PubMed / Full text
  • PLA2R1: expression and function in cancer. / 08.2014 / PubMed / Full text
  • Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing. / 05.2014 / PubMed / Full text

MMP9[править]

  • EGR1 promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling. / 01.09.2019 / PubMed / Full text
  • [Effect of saponins extracted from Panax japonicas on inhibiting myocardial fibrosis by TGF-β1/Smad3 signaling pathway in aging rats]. / 11.2018 / PubMed / Full text
  • Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9. / 2018 / PubMed / Full text
  • Oxidative stress induces p38MAPK-dependent senescence in the feto-maternal interface cells. / 07.2018 / PubMed / Full text
  • Activation of DNA demethylases attenuates aging-associated arterial stiffening and hypertension. / 08.2018 / PubMed / Full text
  • Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice. / 03.2018 / PubMed / Full text
  • Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1. / 04.2017 / PubMed / Full text
  • Secondhand Smoke Exposure Enhances Cardiac Fibrosis Effects on the Aging Rat Hearts. / 09.2016 / PubMed / Full text
  • Transcriptome Analysis of B Cell Immune Functions in Periodontitis: Mucosal Tissue Responses to the Oral Microbiome in Aging. / 2016 / PubMed / Full text
  • Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. / 10.2016 / PubMed / Full text
  • Differential Matrix Metalloprotease (MMP) Expression Profiles Found in Aged Gingiva. / 2016 / PubMed / Full text
  • Inflammageing assessed by MMP9 in normal Japanese individuals and the patients with Werner syndrome. / 05.2016 / PubMed / Full text
  • Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates. / 05.2016 / PubMed / Full text
  • The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4. / 05.2016 / PubMed / Full text
  • Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. / 02.11.2015 / PubMed / Full text
  • Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition. / 06.11.2015 / PubMed / Full text
  • Fat and Sucrose Intake Induces Obesity-Related Bone Metabolism Disturbances: Kinetic and Reversibility Studies in Growing and Adult Rats. / 01.2016 / PubMed / Full text
  • Endothelin-1 critically influences cardiac function via superoxide-MMP9 cascade. / 21.04.2015 / PubMed / Full text
  • [The expression of differential and matrix remodelling factors in human buccal epithelium in aging]. / 2013 / PubMed
  • A transcriptional roadmap to the senescence and differentiation of human oral keratinocytes. / 01.2015 / PubMed / Full text

TFEB[править]

  • A Novel Lipofuscin-detecting Marker of Senescence Relates With Hypoxia, Dysregulated Autophagy and With Poor Prognosis in Non-small-cell-lung Cancer. / 11-12.2020 / PubMed / Full text
  • ESC-sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia. / 05.2020 / PubMed / Full text
  • Nitrative Stress-Related Autophagic Insufficiency Participates in Hyperhomocysteinemia-Induced Renal Aging. / 2020 / PubMed / Full text
  • Polyamines reverse immune senescence via the translational control of autophagy. / 01.2020 / PubMed / Full text
  • Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. / 03.10.2019 / PubMed / Full text
  • Insulin-like peptides and the mTOR-TFEB pathway protect [i]Caenorhabditis elegans[/i] hermaphrodites from mating-induced death. / 08.07.2019 / PubMed / Full text
  • Double knockout of Akt2 and AMPK predisposes cardiac aging without affecting lifespan: Role of autophagy and mitophagy. / 01.07.2019 / PubMed / Full text
  • TFEB protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux. / 02.2019 / PubMed / Full text
  • Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity. / 08.2018 / PubMed / Full text
  • Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan. / 15.05.2018 / PubMed / Full text
  • Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids. / 04.2018 / PubMed / Full text
  • Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan. / 22.12.2017 / PubMed / Full text
  • Peroxisomes contribute to oxidative stress in neurons during doxorubicin-based chemotherapy. / 01.2018 / PubMed / Full text
  • TOR-mediated regulation of metabolism in aging. / 12.2017 / PubMed / Full text
  • Nuclear AMPK regulated CARM1 stabilization impacts autophagy in aged heart. / 29.04.2017 / PubMed / Full text
  • TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin. / 16.12.2016 / PubMed / Full text
  • Role of TFEB Mediated Autophagy, Oxidative Stress, Inflammation, and Cell Death in Endotoxin Induced Myocardial Toxicity of Young and Aged Mice. / 2016 / PubMed / Full text
  • Critical role of lysosomes in the dysfunction of human Cardiac Stem Cells obtained from failing hearts. / 01.08.2016 / PubMed / Full text
  • Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signals. / 22.03.2016 / PubMed / Full text
  • Transcriptional and epigenetic regulation of autophagy in aging. / 2015 / PubMed / Full text

ACE2[править]

  • How Does SARS-CoV-2 Affect the Central Nervous System? A Working Hypothesis. / 2020 / PubMed / Full text
  • Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2. / 2020 / PubMed / Full text
  • A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. / 10.2020 / PubMed / Full text
  • COVID-19 and Senotherapeutics: Any Role for the Naturally-occurring Dipeptide Carnosine? / 07.2020 / PubMed / Full text
  • The dual impact of ACE2 in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions. / 15.09.2020 / PubMed / Full text
  • The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of "inflame-aging". / 09.2020 / PubMed / Full text
  • Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis. / 01.08.2020 / PubMed / Full text
  • A Mouse Model of SARS-CoV-2 Infection and Pathogenesis. / 08.07.2020 / PubMed / Full text
  • COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches. / 08.2020 / PubMed / Full text
  • Gut microbiota and Covid-19- possible link and implications. / 08.2020 / PubMed / Full text
  • Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes. / 06.2020 / PubMed / Full text
  • Restoration of the Renin-Angiotensin System Balance Is a Part of the Effect of Fasting on Cardiovascular Rejuvenation: Role of Age and Fasting Models. / 08.2020 / PubMed / Full text
  • Angiotensin 1-7 alleviates aging-associated muscle weakness and bone loss, but is not associated with accelerated aging in ACE2-knockout mice. / 30.09.2019 / PubMed / Full text
  • Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study. / 14.05.2019 / PubMed / Full text
  • The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system. / 03.2018 / PubMed / Full text
  • Sex differences in the aging pattern of renin-angiotensin system serum peptidases. / 2017 / PubMed / Full text
  • Chymase-dependent production of angiotensin II: an old enzyme in old hearts. / 01.02.2017 / PubMed / Full text
  • Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice. / 2016 / PubMed / Full text
  • Angiotensin converting enzyme 2/Ang-(1-7)/mas axis protects brain from ischemic injury with a tendency of age-dependence. / 05.2014 / PubMed / Full text

CFI[править]

  • Psychosocial Resources for Hedonic Balance, Life Satisfaction and Happiness in the Elderly: A Path Analysis. / 06.08.2020 / PubMed / Full text
  • Validity and Reliability of the Flourishing Scale in a Sample of Older Adults in Iran. / 2020 / PubMed / Full text
  • The decision about retirement: A scale to describe representations and practices of medical doctors and nurses. / 07-08.2016 / PubMed / Full text
  • Family versus intimate partners: Estimating who matters more for health in a 20-year longitudinal study. / 03.2020 / PubMed / Full text
  • Adapting and validating the Rosenberg Self-Esteem Scale for elderly Spanish population. / 02.2020 / PubMed / Full text
  • Mediating Role of Fall-related Efficacy in a Fall Prevention Program. / 01.03.2019 / PubMed / Full text
  • An application of Bayesian measurement invariance to modelling cognition over time in the English Longitudinal Study of Ageing. / 12.2018 / PubMed / Full text
  • [New semantic-cultural validation and psychometric study of the CASP-19 scale in adult and elderly Brazilians]. / 11.10.2018 / PubMed / Full text
  • Mental status evaluation in older adults with cancer: Development of the Mental Health Index-13. / 03.2019 / PubMed / Full text
  • The ACTIVE conceptual framework as a structural equation model. / 01-02.2018 / PubMed / Full text
  • The Utility of the Cognitive Function Instrument (CFI) to Detect Cognitive Decline in Non-Demented Older Adults. / 2017 / PubMed / Full text
  • The effect of age on the response of retinal capillary filling to changes in intraocular pressure measured by optical coherence tomography angiography. / 01.2018 / PubMed / Full text
  • Health, coping and subjective well-being: results of a longitudinal study of elderly Israelis. / 06.2017 / PubMed / Full text
  • Women's intentions to use fertility preservation to prevent age-related fertility decline. / 01.2016 / PubMed / Full text
  • Factorial Structure and Measurement Invariance of the PANAS in Spanish Older Adults. / 03.03.2015 / PubMed / Full text
  • Assessing the factor structure of well-being in older adults: findings from the National Health and Aging Trends Study. / 08.2016 / PubMed / Full text
  • Measuring frailty using self-report and test-based health measures. / 05.2015 / PubMed / Full text
  • CASP-19 special section: how does chronic disease status affect CASP quality of life at older ages? Examining the WHO ICF disability domains as mediators of this relationship. / 07.2015 / PubMed / Full text
  • Differential trajectories of well-being in older adult women: the role of optimism. / 11.2014 / PubMed / Full text

CLU[править]

  • Expression of Clusterin suppresses Cr(VI)-induced premature senescence through activation of PI3K/AKT pathway. / 15.11.2019 / PubMed / Full text
  • Informative combination of CLU rs11136000, serum HDL levels, diabetes, and age as a new piece of puzzle-picture of predictive medicine for cognitive disorders. / 02.2019 / PubMed / Full text
  • Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. / 11.2018 / PubMed / Full text
  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
  • Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text
  • Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer's Disease. / 05.2018 / PubMed / Full text
  • Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study. / 2017 / PubMed / Full text
  • Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
  • An Alzheimer's Disease Genetic Risk Score Predicts Longitudinal Thinning of Hippocampal Complex Subregions in Healthy Older Adults. / 05-06.2016 / PubMed / Full text
  • Genetically-mediated Grey and White Matter Alteration in Normal Elderly Individuals with the CLU-C Allele Gene. / 2016 / PubMed / Full text
  • Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models. / 30.03.2017 / PubMed / Full text
  • Risk-reducing Apolipoprotein E and Clusterin genotypes protect against the consequences of poor vascular health on executive function performance and change in nondemented older adults. / 06.2016 / PubMed / Full text
  • Impact of PICALM and CLU on hippocampal degeneration. / 07.2016 / PubMed / Full text
  • Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. / 04.2016 / PubMed / Full text
  • Apolipoprotein E and Clusterin can magnify effects of personality vulnerability on declarative memory performance in non-demented older adults. / 05.2016 / PubMed / Full text
  • Mesterolone treatment of aging male syndrome improves lower urinary tract symptoms. / 12.2014 / PubMed
  • Combined effects of Alzheimer risk variants in the CLU and ApoE genes on ventricular expansion patterns in the elderly. / 07.05.2014 / PubMed / Full text
  • The benefits of staying active in old age: physical activity counteracts the negative influence of PICALM, BIN1, and CLU risk alleles on episodic memory functioning. / 06.2014 / PubMed / Full text
  • Age-dependent effect of Alzheimer's risk variant of CLU on EEG alpha rhythm in non-demented adults. / 2013 / PubMed / Full text

GDF15[править]

  • Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging. / 31.10.2020 / PubMed / Full text
  • Growth differentiation factor 15 protects against the aging-mediated systemic inflammatory response in humans and mice. / 08.2020 / PubMed / Full text
  • Analysis of Epigenetic Age Predictors in Pain-Related Conditions. / 2020 / PubMed / Full text
  • GDF15 Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness. / 2020 / PubMed / Full text
  • GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis. / 01.10.2019 / PubMed / Full text
  • Senescence-associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15. / 12.2019 / PubMed / Full text
  • mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism. / 06.2019 / PubMed / Full text
  • Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
  • Growth differentiation factor 15 (GDF15): A survival protein with therapeutic potential in metabolic diseases. / 06.2019 / PubMed / Full text
  • [The role of «Youth and aging proteins» in essential hypertension pathogenesis.] / 2018 / PubMed
  • A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup. / 12.2018 / PubMed / Full text
  • Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
  • Plasma proteomic signature of age in healthy humans. / 10.2018 / PubMed / Full text
  • Human Aging and Longevity Are Characterized by High Levels of Mitokines. / 23.04.2019 / PubMed / Full text
  • Induction of Growth Differentiation Factor 15 in Skeletal Muscle of Old Taurine Transporter Knockout Mouse. / 2018 / PubMed / Full text
  • Cigarette Smoke Induces Human Airway Epithelial Senescence via Growth Differentiation Factor 15 Production. / 09.2016 / PubMed / Full text
  • Secreted growth differentiation factor 15 as a potential biomarker for mitochondrial dysfunctions in aging and age-related disorders. / 03.2016 / PubMed / Full text
  • GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells. / 01.03.2016 / PubMed / Full text
  • hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling. / 08.2014 / PubMed / Full text

MCC[править]

  • Multiple chronic conditions and risk of cognitive impairment and dementia among older Americans: findings from the Aging, Demographics, and Memory Study (ADAMS). / 07.07.2020 / PubMed / Full text
  • Behaviour consistency is a sensitive tool for distinguishing the effects of aging on physical activity. / 01.07.2020 / PubMed / Full text
  • Burden on Caregivers of Adults with Multiple Chronic Conditions: Intersectionality of Age, Gender, Education level, Employment Status, and Impact on Social Life. / 09.2020 / PubMed / Full text
  • Using the Technology Acceptance Model to Explore User Experience, Intent to Use, and Use Behavior of a Patient Portal Among Older Adults With Multiple Chronic Conditions: Descriptive Qualitative Study. / 08.04.2019 / PubMed / Full text
  • Trends in Risk of Limitations in Instrumental Activities of Daily Living Over Age in Older Persons With and Without Multiple Chronic Conditions. / 01.01.2020 / PubMed / Full text
  • Association between treatment of superficial bladder cancer and 10-year mortality in older adults with multiple chronic conditions. / 01.12.2018 / PubMed / Full text
  • The AGING Initiative experience: a call for sustained support for team science networks. / 18.05.2018 / PubMed / Full text
  • Evidence on selection, optimization, and compensation strategies to optimize aging with multiple chronic conditions: A literature review. / 09-10.2018 / PubMed / Full text
  • Chronic disease burden predicts food insecurity among older adults. / 06.2018 / PubMed / Full text
  • Differences Between Younger and Older US Adults With Multiple Chronic Conditions. / 07.09.2017 / PubMed / Full text
  • Prevalence, Correlates, and Time Trends of Multiple Chronic Conditions Among Israeli Adults: Estimates From the Israeli National Health Interview Survey, 2014-2015. / 10.08.2017 / PubMed / Full text
  • Seed incorporation during vinification and its impact on chemical and organoleptic properties in Syzygium cumini wine. / 15.12.2017 / PubMed / Full text
  • Research Priorities to Advance the Health and Health Care of Older Adults with Multiple Chronic Conditions. / 07.2017 / PubMed / Full text
  • The ACHRU-CPP versus usual care for older adults with type-2 diabetes and multiple chronic conditions and their family caregivers: study protocol for a randomized controlled trial. / 06.02.2017 / PubMed / Full text
  • Changes in Depressive Symptoms among Older Adults with Multiple Chronic Conditions: Role of Positive and Negative Social Support. / 26.12.2016 / PubMed / Full text
  • Sex-specific effects of cytotoxic chemotherapy agents cyclophosphamide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus - an aging connection. / 04.2016 / PubMed / Full text
  • Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin. / 01.05.2016 / PubMed / Full text
  • Corrupt practices negatively influenced food security and live expectancy in developing countries. / 2015 / PubMed / Full text
  • Decision-making and cancer screening: a qualitative study of older adults with multiple chronic conditions. / 03.2015 / PubMed / Full text

MMP2[править]

  • Cellular retinoic acid binding protein-II expression and its potential role in skin aging. / 18.03.2019 / PubMed / Full text
  • [Effect of saponins extracted from Panax japonicas on inhibiting myocardial fibrosis by TGF-β1/Smad3 signaling pathway in aging rats]. / 11.2018 / PubMed / Full text
  • TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity. / 07.2019 / PubMed / Full text
  • MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1. / 12.2018 / PubMed / Full text
  • PM2.5 promotes abdominal aortic aneurysm formation in angiotensin Ⅱ-infused apoe-/- mice. / 08.2018 / PubMed / Full text
  • Activation of DNA demethylases attenuates aging-associated arterial stiffening and hypertension. / 08.2018 / PubMed / Full text
  • MMP2-A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction. / 19.01.2018 / PubMed / Full text
  • Systemic analysis of gene expression profiles in porcine granulosa cells during aging. / 14.11.2017 / PubMed / Full text
  • Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1. / 04.2017 / PubMed / Full text
  • Secondhand Smoke Exposure Enhances Cardiac Fibrosis Effects on the Aging Rat Hearts. / 09.2016 / PubMed / Full text
  • Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. / 10.2016 / PubMed / Full text
  • Stimulation of cellular senescent processes, including secretory phenotypes and anti-oxidant responses, after androgen deprivation therapy in human prostate cancer. / 01.2017 / PubMed / Full text
  • Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses. / 07.2016 / PubMed / Full text
  • Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model. / 01.05.2016 / PubMed / Full text
  • Correlations between Photodegradation of Bisretinoid Constituents of Retina and Dicarbonyl Adduct Deposition. / 06.11.2015 / PubMed / Full text
  • Fat and Sucrose Intake Induces Obesity-Related Bone Metabolism Disturbances: Kinetic and Reversibility Studies in Growing and Adult Rats. / 01.2016 / PubMed / Full text
  • Differential levels of cathepsin B and L in serum between young and aged healthy people and their association with matrix metalloproteinase 2. / 09-10.2015 / PubMed / Full text
  • [The expression of differential and matrix remodelling factors in human buccal epithelium in aging]. / 2013 / PubMed
  • Metzincins and related genes in experimental renal ageing: towards a unifying fibrosis classifier across species. / 06.2014 / PubMed / Full text

NAMPT[править]

  • Over-expression of Nicotinamide phosphoribosyltransferase in mouse cells confers protective effect against oxidative and ER stress-induced premature senescence. / 08.2020 / PubMed / Full text
  • Resistance training increases muscle NAD and NADH concentrations as well as NAMPT protein levels and global sirtuin activity in middle-aged, overweight, untrained individuals. / 05.05.2020 / PubMed / Full text
  • Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase (NAMPT) and Sirtuin-1 (SIRT-1) Pathway in Obesity and T2DM: Modulation by Metformin and Macronutrient Intake. / 2019 / PubMed / Full text
  • Aerobic and resistance exercise training reverses age-dependent decline in NAD salvage capacity in human skeletal muscle. / 07.2019 / PubMed / Full text
  • Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice. / 06.08.2019 / PubMed / Full text
  • lncRNA GAS5/miR-223/NAMPT axis modulates the cell proliferation and senescence of endothelial progenitor cells through PI3K/AKT signaling. / 09.2019 / PubMed / Full text
  • Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training. / 2018 / PubMed / Full text
  • Loss of NAMPT in aging retinal pigment epithelium reduces NAD availability and promotes cellular senescence. / 12.06.2018 / PubMed / Full text
  • Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating SIRT1 activity and antioxidant gene expression in mouse cells. / 12.2017 / PubMed / Full text
  • Deletion of Nampt in Projection Neurons of Adult Mice Leads to Motor Dysfunction, Neurodegeneration, and Death. / 29.08.2017 / PubMed / Full text
  • Nicotinamide Phosphoribosyltransferase in Smooth Muscle Cells Maintains Genome Integrity, Resists Aortic Medial Degeneration, and Is Suppressed in Human Thoracic Aortic Aneurysm Disease. / 09.06.2017 / PubMed / Full text
  • Effect of lifelong football training on the expression of muscle molecular markers involved in healthy longevity. / 04.2017 / PubMed / Full text
  • Aging and caloric restriction impact adipose tissue, adiponectin, and circulating lipids. / 06.2017 / PubMed / Full text
  • Autophagic homeostasis is required for the pluripotency of cancer stem cells. / 02.2017 / PubMed / Full text
  • NAMPT regulates senescence, proliferation, and migration of endothelial progenitor cells through the SIRT1 AS lncRNA/miR-22/SIRT1 pathway. / 23.09.2016 / PubMed / Full text
  • Hepatic NAD( ) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing. / 08.2016 / PubMed / Full text
  • Targeting Nicotinamide Phosphoribosyltransferase as a Potential Therapeutic Strategy to Restore Adult Neurogenesis. / 06.2016 / PubMed / Full text
  • A critical role of nicotinamide phosphoribosyltransferase in human telomerase reverse transcriptase induction by resveratrol in aortic smooth muscle cells. / 10.05.2015 / PubMed / Full text
  • Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons. / 08.2014 / PubMed / Full text

SST[править]

  • The distance to death perceptions of older adults explain why they age in place: A theoretical examination. / 09.2020 / PubMed / Full text
  • Population Segmentation Based on Healthcare Needs: Validation of a Brief Clinician-Administered Tool. / 30.06.2020 / PubMed / Full text
  • Examination on how emotion regulation mediates the relationship between future time perspective and well-being: a counter-evidence to the socioemotional selectivity theory. / 03.2020 / PubMed / Full text
  • Shear-Wave and Strain Ultrasound Elastography of the Supraspinatus and Infraspinatus Tendons in Patients with Idiopathic Adhesive Capsulitis of the Shoulder: A Prospective Case-Control Study. / 07.2019 / PubMed / Full text
  • Counting down while time flies: implications of age-related time acceleration for goal pursuit across adulthood. / 04.2019 / PubMed / Full text
  • Relative costs and benefits of alternative reproductive phenotypes at different temperatures - genotype-by-environment interactions in a sexually selected trait. / 11.07.2018 / PubMed / Full text
  • Climate change and functional traits affect population dynamics of a long-lived seabird. / 07.2018 / PubMed / Full text
  • Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography. / 12.2017 / PubMed / Full text
  • The roles of chronological age and time perspective in memory positivity. / 07.2018 / PubMed / Full text
  • Atypical Red Blood Cells Are Prevalent in California Sea Lion Pups Born during Anomalous Sea Surface Temperature Events. / 09-10.2017 / PubMed / Full text
  • DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers. / 07.2017 / PubMed / Full text
  • Sleep/wake movement velocities, trajectories and micro-arousals during maturation in rats. / 07.02.2017 / PubMed / Full text
  • When meaning matters more: Media preferences across the adult life span. / 08.2016 / PubMed / Full text
  • An improved spatial span test of visuospatial memory. / 09.2016 / PubMed / Full text
  • Hypermethylation of BDNF and SST Genes in the Orbital Frontal Cortex of Older Individuals: A Putative Mechanism for Declining Gene Expression with Age. / 10.2015 / PubMed / Full text
  • Sleep/Wake Dynamics Changes during Maturation in Rats. / 2015 / PubMed / Full text
  • Sleep disturbance associated with rotator cuff tear: correction with arthroscopic rotator cuff repair. / 06.2015 / PubMed / Full text
  • A cortical disinhibitory circuit for enhancing adult plasticity. / 27.01.2015 / PubMed / Full text
  • Telemetry and random-walk models reveal complex patterns of partial migration in a large marine predator. / 11.2013 / PubMed / Full text

UCP1[править]

  • Muscle-dependent regulation of adipose tissue function in long-lived growth hormone-mutant mice. / 28.05.2020 / PubMed / Full text
  • Lack of UCP1 stimulates fatty liver but mediates UCP1-independent action of beige fat to improve hyperlipidemia in Apoe knockout mice. / 01.07.2020 / PubMed / Full text
  • Postnatal leptin surge is critical for the transient induction of the developmental beige adipocytes in mice. / 01.04.2020 / PubMed / Full text
  • Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice. / 05.12.2019 / PubMed / Full text
  • An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise. / 19.08.2019 / PubMed / Full text
  • Brown and Beige Adipose Tissue and Aging. / 2019 / PubMed / Full text
  • Resveratrol and HIV-protease inhibitors control UCP1 expression through opposite effects on p38 MAPK phosphorylation in human adipocytes. / 02.2020 / PubMed / Full text
  • Circulating factors present in the sera of naturally skinny people may influence cell commitment and adipocyte differentiation of mesenchymal stromal cells. / 26.03.2019 / PubMed / Full text
  • Assessment of the Aging of the Brown Adipose Tissue by F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna . / 2018 / PubMed / Full text
  • Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice. / 08.2018 / PubMed / Full text
  • Rapamycin Reverses Metabolic Deficits in Lamin A/C-Deficient Mice. / 06.12.2016 / PubMed / Full text
  • Targeted mitochondrial uncoupling beyond UCP1 - The fine line between death and metabolic health. / 03.2017 / PubMed / Full text
  • Methionine restriction improves renal insulin signalling in aged kidneys. / 07.2016 / PubMed / Full text
  • Age-related changes of serum mitochondrial uncoupling 1, rumen and rectal temperature in goats. / 07.2016 / PubMed / Full text
  • Sestrin2, a Regulator of Thermogenesis and Mitohormesis in Brown Adipose Tissue. / 2015 / PubMed / Full text
  • [The role of uncoupling proteins in mechanisms of protection from oxidative stress]. / 2015 / PubMed / Full text
  • Miglitol protects against age-dependent weight gain in mice: A potential role of increased UCP1 content in brown adipose tissue. / 2015 / PubMed / Full text
  • Shc depletion stimulates brown fat activity in vivo and in vitro. / 12.2014 / PubMed / Full text
  • Inducible brown adipocytes in subcutaneous inguinal white fat: the role of continuous sympathetic stimulation. / 01.11.2014 / PubMed / Full text

CDKN1A[править]

  • Involvement of CDKN1A (p21) in cellular senescence in response to heat and irradiation stress during preimplantation development. / 05.2020 / PubMed / Full text
  • Chromatin remodeling factor BAZ1A regulates cellular senescence in both cancer and normal cells. / 15.07.2019 / PubMed / Full text
  • Histone demethylase KDM6B regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells. / 08.2019 / PubMed / Full text
  • A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. / 2018 / PubMed / Full text
  • Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS. / 10.2018 / PubMed / Full text
  • Conditioned medium from stimulated macrophages inhibits growth but induces an inflammatory phenotype in breast cancer cells. / 10.2018 / PubMed / Full text
  • DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice. / 02.2018 / PubMed / Full text
  • Cellular Senescence in Mouse Hippocampus After Irradiation and the Role of p53 and p21. / 01.04.2017 / PubMed / Full text
  • p16 enhances the transcriptional and the apoptotic functions of p53 through DNA-dependent interaction. / 07.2017 / PubMed / Full text
  • Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing. / 14.02.2017 / PubMed / Full text
  • Phosphorylation of MITF by AKT affects its downstream targets and causes TP53-dependent cell senescence. / 11.2016 / PubMed / Full text
  • Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus. / 18.05.2016 / PubMed / Full text
  • Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence. / 01.2016 / PubMed / Full text
  • TP53inp1 Gene Is Implicated in Early Radiation Response in Human Fibroblast Cells. / 23.10.2015 / PubMed / Full text
  • Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium. / 06.2015 / PubMed / Full text
  • Tocotrienol-rich fraction prevents cellular aging by modulating cell proliferation signaling pathways. / 2015 / PubMed / Full text
  • Orphan nuclear receptor TLX functions as a potent suppressor of oncogene-induced senescence in prostate cancer via its transcriptional co-regulation of the CDKN1A (p21(WAF1) (/) (CIP1) ) and SIRT1 genes. / 05.2015 / PubMed / Full text
  • Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease. / 2014 / PubMed / Full text

DNMT1[править]

  • DNA Methyltransferase 1 (DNMT1) Function Is Implicated in the Age-Related Loss of Cortical Interneurons. / 2020 / PubMed / Full text
  • Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords. / 02.2019 / PubMed / Full text
  • Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. / 05.11.2018 / PubMed / Full text
  • Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells. / 15.09.2018 / PubMed / Full text
  • Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating DNMT1 via ZEB1. / 16.02.2018 / PubMed / Full text
  • Microrna-217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1. / 16.05.2017 / PubMed / Full text
  • A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis. / 19.05.2017 / PubMed / Full text
  • miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1. / 09.03.2017 / PubMed / Full text
  • Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx. / 07.03.2017 / PubMed / Full text
  • The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence. / 03.03.2017 / PubMed / Full text
  • Short term methionine restriction increases hepatic global DNA methylation in adult but not young male C57BL/6J mice. / 02.2017 / PubMed / Full text
  • In vivo and in silico studies to identify mechanisms associated with Nurr1 modulation following early life exposure to permethrin in rats. / 06.01.2017 / PubMed / Full text
  • Age-Related Changes in DNA Methylation Associated with Shifting Th1/Th2 Balance. / 12.2016 / PubMed / Full text
  • CDK4-CDK6 inhibitors induce autophagy-mediated degradation of DNMT1 and facilitate the senescence antitumor response. / 02.10.2016 / PubMed / Full text
  • Developmental lead exposure and lifespan alterations in epigenetic regulators and their correspondence to biomarkers of Alzheimer's disease. / 2016 / PubMed / Full text
  • Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study. / 08.2016 / PubMed / Full text
  • SIRT1 affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing. / 24.06.2015 / PubMed / Full text
  • The Interplay Between miR-148a and DNMT1 Might be Exploited for Pancreatic Cancer Therapy. / 2015 / PubMed / Full text

DNMT3A[править]

  • Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells. / 09.09.2020 / PubMed / Full text
  • Collagens and DNA methyltransferases in mare endometrosis. / 09.2019 / PubMed / Full text
  • Age-related clonal haemopoiesis is associated with increased epigenetic age. / 19.08.2019 / PubMed / Full text
  • Alcohol Extracts From [i]Ganoderma lucidum[/i] Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents. / 2019 / PubMed / Full text
  • Targeted, Amplicon-Based, Next-Generation Sequencing to Detect Age-Related Clonal Hematopoiesis. / 2019 / PubMed / Full text
  • Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development. / 06.2019 / PubMed / Full text
  • Concise Review: Age-Related Clonal Hematopoiesis: Stem Cells Tempting the Devil. / 09.2018 / PubMed / Full text
  • Effects of Parental Aging During Embryo Development and Adult Life: The Case of Nothobranchius furzeri. / 04.2018 / PubMed / Full text
  • Genetic Biomarkers on Age-Related Cognitive Decline. / 2017 / PubMed / Full text
  • An inflammatory environment containing TNFα favors Tet2-mutant clonal hematopoiesis. / 03.2018 / PubMed / Full text
  • Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text
  • How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress? / 2017 / PubMed / Full text
  • miR-194 functions as a novel modulator of cellular senescence in mouse embryonic fibroblasts. / 03.2017 / PubMed / Full text
  • A primer for epigenetics of hematological malignancies. / 2016 / PubMed / Full text
  • Methylation of LOXL1 Promoter by DNMT3A in Aged Human Skin Fibroblasts. / 04.2017 / PubMed / Full text
  • Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy. / 10.2016 / PubMed / Full text
  • No association of the variant rs11887120 in DNMT3A with cognitive decline in individuals with mild cognitive impairment. / 05.2016 / PubMed / Full text
  • DNMT3A moderates cognitive decline in subjects with mild cognitive impairment: replicated evidence from two mild cognitive impairment cohorts. / 2015 / PubMed / Full text

E2F1[править]

  • Regulation of E2F1 activity via PKA-mediated phosphorylations. / 2020 / PubMed / Full text
  • Astragaloside IV ameliorates radiation-induced senescence via antioxidative mechanism. / 08.2020 / PubMed / Full text
  • E2F1 mediates the downregulation of POLD1 in replicative senescence. / 07.2019 / PubMed / Full text
  • Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing NRARP. / 10.11.2018 / PubMed / Full text
  • Downregulation of FOXP1 correlates with tendon stem/progenitor cells aging. / 26.09.2018 / PubMed / Full text
  • Loss of circadian protein TIMELESS accelerates the progression of cellular senescence. / 18.09.2018 / PubMed / Full text
  • Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence. / 30.04.2018 / PubMed / Full text
  • Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text
  • Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation / 27.09.2017 / PubMed / Full text
  • Senescence-associated microRNAs target cell cycle regulatory genes in normal human lung fibroblasts. / 01.10.2017 / PubMed / Full text
  • Neuronal tetraploidization in the cerebral cortex correlates with reduced cognition in mice and precedes and recapitulates Alzheimer's-associated neuropathology. / 08.2017 / PubMed / Full text
  • Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle. / 30.01.2017 / PubMed / Full text
  • Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression. / 21.11.2016 / PubMed / Full text
  • The activation of OR51E1 causes growth suppression of human prostate cancer cells. / 26.07.2016 / PubMed / Full text
  • Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses. / 07.05.2017 / PubMed / Full text
  • CBX8 antagonizes the effect of Sirtinol on premature senescence through the AKT-RB-E2F1 pathway in K562 leukemia cells. / 22.01.2016 / PubMed / Full text
  • Nucleolar repression facilitates initiation and maintenance of senescence. / 2015 / PubMed / Full text
  • Targeted gene mutation of E2F1 evokes age-dependent synaptic disruption and behavioral deficits. / 06.2014 / PubMed / Full text

EPO[править]

  • Regulation of muscle and metabolic physiology by hypothalamic erythropoietin independently of its peripheral action. / 02.2020 / PubMed / Full text
  • Red Blood Cell Lifespan Shortening in Patients with Early-Stage Chronic Kidney Disease. / 2019 / PubMed / Full text
  • Age-Dependent Systemic Effects of a Systemic Intermittent Hypoxic Therapy [i]In Vivo[/i]. / 09.2019 / PubMed / Full text
  • Erythropoietin does not improve fracture healing in aged mice. / 15.07.2019 / PubMed / Full text
  • Dose-response relationship of intermittent normobaric hypoxia to stimulate erythropoietin in the context of health promotion in young and old people. / 05.2019 / PubMed / Full text
  • rhEPO Enhances Cellular Anti-oxidant Capacity to Protect Long-Term Cultured Aging Primary Nerve Cells. / 08.2017 / PubMed / Full text
  • [Effects of recombinant human erythropoietin on brain-derived neurotrophic factor expression in different brain regions of aging rats]. / 20.04.2016 / PubMed / Full text
  • Warming Up to New Possibilities with the Capsaicin Receptor TRPV1: mTOR, AMPK, and Erythropoietin. / 2017 / PubMed / Full text
  • The Anti-Aging Effect of Erythropoietin via the ERK/Nrf2-ARE Pathway in Aging Rats. / 03.2017 / PubMed / Full text
  • Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations. / 01.2017 / PubMed / Full text
  • Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life Expectancy. / 2016 / PubMed / Full text
  • Erythropoietin Does Not Enhance Skeletal Muscle Protein Synthesis Following Exercise in Young and Older Adults. / 2016 / PubMed / Full text
  • Oxidative stress induces the decline of brain EPO expression in aging rats. / 10.2016 / PubMed / Full text
  • Sub-acute systemic erythropoietin administration reduces ischemic brain injury in an age-dependent manner. / 14.06.2016 / PubMed / Full text
  • Erythropoietin Attenuates the Memory Deficits in Aging Rats by Rescuing the Oxidative Stress and Inflammation and Promoting BDNF Releasing. / 10.2016 / PubMed / Full text
  • rhEPO affects apoptosis in hippocampus of aging rats by upregulating SIRT1. / 2015 / PubMed / Full text
  • Coated dextrin microcapsules of amlodipine incorporable into orally disintegrating tablets for geriatric patients. / 10.2014 / PubMed / Full text
  • Neocytolysis: none, one or many? A reappraisal and future perspectives. / 2014 / PubMed / Full text

GAL[править]

  • Overexpression of Pitx1 attenuates the senescence of chondrocytes from osteoarthritis degeneration cartilage-A self-controlled model for studying the etiology and treatment of osteoarthritis. / 02.2020 / PubMed / Full text
  • β-Caryophyllene Reduces DNA Oxidation and the Overexpression of Glial Fibrillary Acidic Protein in the Prefrontal Cortex and Hippocampus of d-Galactose-Induced Aged BALB/c Mice. / 05.2020 / PubMed / Full text
  • Senescence-associated β-galactosidase activity in the developing avian retina. / 09.2019 / PubMed / Full text
  • Zeaxanthin Isolated from [i]Dunaliella salina[/i] Microalgae Ameliorates Age Associated Cardiac Dysfunction in Rats through Stimulation of Retinoid Receptors. / 14.05.2019 / PubMed / Full text
  • Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway. / 15.07.2019 / PubMed / Full text
  • MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts. / 2018 / PubMed / Full text
  • Manipulation of molecular pathways and senescence hallmarks by natural compounds in fibroblast cells. / 04.2019 / PubMed / Full text
  • Ellagic acid reveals promising anti-aging effects against d-galactose-induced aging on human neuroblastoma cell line, SH-SY5Y: A mechanistic study. / 12.2018 / PubMed / Full text
  • Molecular and biochemical evidence on the protective role of ellagic acid and silybin against oxidative stress-induced cellular aging. / 04.2018 / PubMed / Full text
  • Hyperphosphatemia induces senescence in human endothelial cells by increasing endothelin-1 production. / 12.2017 / PubMed / Full text
  • Carnosine Treatment Diminished Oxidative Stress and Glycation Products in Serum and Tissues of D-Galactose-Treated Rats. / 2018 / PubMed / Full text
  • Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study. / 03.2016 / PubMed / Full text
  • Carnosine and taurine treatments diminished brain oxidative stress and apoptosis in D-galactose aging model. / 04.2016 / PubMed / Full text
  • The role of TORC1 in muscle development in Drosophila. / 13.04.2015 / PubMed / Full text
  • N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models. / 2015 / PubMed / Full text
  • Five years of interdisciplinary research on ageing and technology: Outcomes of the Lower Saxony Research Network Design of Environments for Ageing (GAL)--an introduction to this Special Issue on Ageing and Technology. / 09-12.2014 / PubMed / Full text
  • Information and communication technologies for promoting and sustaining quality of life, health and self-sufficiency in ageing societies--outcomes of the Lower Saxony Research Network Design of Environments for Ageing (GAL). / 09-12.2014 / PubMed / Full text
  • Cyanidin-3-O-galactoside and blueberry extracts supplementation improves spatial memory and regulates hippocampal ERK expression in senescence-accelerated mice. / 03.2014 / PubMed / Full text

NQO1[править]

  • Augmentation of cellular NAD by NQO1 enzymatic action improves age-related hearing impairment. / 10.2019 / PubMed / Full text
  • Well-aging: A new strategy for skin homeostasis under multi-stressed conditions. / 02.2020 / PubMed / Full text
  • Limitations to adaptive homeostasis in an hyperoxia-induced model of accelerated ageing. / 06.2019 / PubMed / Full text
  • Link between cardiac function and the antioxidative defense mechanism in aged rats. / 11.06.2019 / PubMed / Full text
  • [Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats]. / 07.2018 / PubMed / Full text
  • Benefits of Caloric Restriction in Longevity and Chemical-Induced Tumorigenesis Are Transmitted Independent of NQO1. / 16.01.2019 / PubMed / Full text
  • Overexpression of CYB5R3 and NQO1, two NAD -producing enzymes, mimics aspects of caloric restriction. / 08.2018 / PubMed / Full text
  • Sargassum fusiforme Polysaccharide Rejuvenat es the Small Intestine in Mice Through Altering its Physiol ogy and Gut Microbiota Composition. / 2017 / PubMed / Full text
  • Apigenin exhibits protective effects in a mouse model of d-galactose-induced aging via activating the Nrf2 pathway. / 21.06.2017 / PubMed / Full text
  • The ontogeny and population variability of human hepatic dihydronicotinamide riboside:quinone oxidoreductase (NQO2). / 08.2017 / PubMed / Full text
  • Gardenia jasminoides extract-capped gold nanoparticles reverse hydrogen peroxide-induced premature senescence. / 11.2016 / PubMed / Full text
  • Stimulation of cellular senescent processes, including secretory phenotypes and anti-oxidant responses, after androgen deprivation therapy in human prostate cancer. / 01.2017 / PubMed / Full text
  • Exercise-induced Nrf2-signaling is impaired in aging. / 07.2016 / PubMed / Full text
  • Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress. / 05.04.2016 / PubMed / Full text
  • The Ontogeny and Population Variability of Human Hepatic NADPH Dehydrogenase Quinone Oxido-Reductase 1 (NQO1). / 07.2016 / PubMed / Full text
  • Acetaminophen hepatotoxicity in mice: Effect of age, frailty and exposure type. / 01.2016 / PubMed / Full text
  • NQO1 Stabilizes p53 in Response to Oncogene-Induced Senescence. / 2015 / PubMed / Full text
  • Neophobia, NQO1 and SIRT1 as premorbid and prodromal indicators of AD in 3xTg-AD mice. / 01.09.2014 / PubMed / Full text

TREM2[править]

  • Loss of TREM2 Confers Resilience to Synaptic and Cognitive Impairment in Aged Mice. / 09.12.2020 / PubMed / Full text
  • Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer's Disease Brain. / 2020 / PubMed / Full text
  • Knockdown of astrocytic TREM2 in the hippocampus relieves cognitive decline in elderly male mice. / 15.01.2021 / PubMed / Full text
  • Immune Signaling in Neurodegeneration. / 16.04.2019 / PubMed / Full text
  • The Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) as Expression of the Relationship between Microglia and Alzheimer's Disease: A Novel Marker for a Promising Pathway to Explore. / 2019 / PubMed / Full text
  • TREM2 triggers microglial density and age-related neuronal loss. / 03.2019 / PubMed / Full text
  • Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy. / 02.10.2018 / PubMed / Full text
  • Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text
  • Differential Phagocytic Properties of CD45 Microglia and CD45 Brain Mononuclear Phagocytes-Activation and Age-Related Effects. / 2018 / PubMed / Full text
  • Microglia and Aging: The Role of the TREM2-DAP12 and CX3CL1-CX3CR1 Axes. / 22.01.2018 / PubMed / Full text
  • A Tale of Two Genes: Microglial Apoe and Trem2. / 19.09.2017 / PubMed / Full text
  • TREM2, Microglia, and Neurodegenerative Diseases. / 06.2017 / PubMed / Full text
  • Neuroprotective Effect of TREM-2 in Aging and Alzheimer's Disease Model. / 2017 / PubMed / Full text
  • Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's disease. / 27.04.2016 / PubMed / Full text
  • Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease. / 18.02.2016 / PubMed / Full text
  • Dark microglia: A new phenotype predominantly associated with pathological states. / 05.2016 / PubMed / Full text
  • TREM2 Overexpression has No Improvement on Neuropathology and Cognitive Impairment in Aging APPswe/PS1dE9 Mice. / 03.2017 / PubMed / Full text
  • TREM2 sustains microglial expansion during aging and response to demyelination. / 05.2015 / PubMed / Full text

TSPO[править]

  • Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge. / 2019 / PubMed / Full text
  • Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study. / 10.11.2019 / PubMed / Full text
  • Effects of age, BMI and sex on the glial cell marker [[TSPO]] - a multicentre [ C]PBR28 HRRT PET study. / 10.2019 / PubMed / Full text
  • Concentration, distribution, and influence of aging on the 18 kDa translocator protein in human brain: Implications for brain imaging studies. / 05.2020 / PubMed / Full text
  • Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study. / 06.11.2018 / PubMed / Full text
  • Age Influences Microglial Activation After Cuprizone-Induced Demyelination. / 2018 / PubMed / Full text
  • [[TSPO]] ligand PK11195 improves Alzheimer-related outcomes in aged female 3xTg-AD mice. / 14.09.2018 / PubMed / Full text
  • Imaging studies of the HIV-infected brain. / 2018 / PubMed / Full text
  • Steroidogenic abnormalities in translocator protein knockout mice and significance in the aging male. / 02.01.2018 / PubMed / Full text
  • Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study. / 12.2017 / PubMed / Full text
  • Depiction of microglial activation in aging and dementia: Positron emission tomography with [ C]DPA713 versus [ C]( R)PK11195. / 03.2017 / PubMed / Full text
  • In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by 18F-GE180 [[TSPO]] MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice. / 25.11.2015 / PubMed / Full text
  • [[TSPO]] in a murine model of Sandhoff disease: presymptomatic marker of neurodegeneration and disease pathophysiology. / 01.2016 / PubMed / Full text
  • Translocator protein: pharmacology and steroidogenesis. / 08.2015 / PubMed / Full text
  • Translocator protein (TSPO) role in aging and Alzheimer's disease. / 2014 / PubMed / Full text
  • Evaluation of basal ganglia and thalamic inflammation in children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection and tourette syndrome: a positron emission tomographic (PET) study using 11C-[R]-PK11195. / 05.2015 / PubMed / Full text
  • Genetic analysis of d[[TSPO]], an outer mitochondrial membrane protein, reveals its functions in apoptosis, longevity, and Ab42-induced neurodegeneration. / 06.2014 / PubMed / Full text
  • Comparing amyloid-β deposition, neuroinflammation, glucose metabolism, and mitochondrial complex I activity in brain: a PET study in aged monkeys. / 11.2014 / PubMed / Full text

UCP2[править]

  • Potential Role of Leptin in Cardiac Steatosis Induced by Highly Saturated Fat Intake during Adolescence. / 10.2019 / PubMed / Full text
  • Effect of Initial Aging and High-Fat/High-Fructose Diet on Mitochondrial Bioenergetics and Oxidative Status in Rat Brain. / 11.2019 / PubMed / Full text
  • Decreased uncoupling protein 2 expression in aging retinal pigment epithelial cells. / 2019 / PubMed / Full text
  • The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature. / 01.08.2019 / PubMed / Full text
  • G-1 exhibit antidepressant effect, increase of hippocampal ERs expression and improve hippocampal redox status in aged female rats. / 01.02.2019 / PubMed / Full text
  • Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts. / 21.06.2018 / PubMed / Full text
  • Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1α pathway. / 02.2018 / PubMed / Full text
  • Pleiotropic effects of UCP2-UCP3 variability on leucocyte telomere length and glucose homeostasis. / 06.2017 / PubMed / Full text
  • Thyroid hormone-stimulated increases in PGC-1α and UCP2 promote life history-specific endocrine changes and maintain a lipid-based metabolism. / 01.02.2017 / PubMed / Full text
  • Uncoupling protein 2 deficiency results in higher neutrophil counts and lower B-cell counts during aging in mice. / 11.2016 / PubMed / Full text
  • Voluntary Running Aids to Maintain High Body Temperature in Rats Bred for High Aerobic Capacity. / 2016 / PubMed / Full text
  • Uncoupling protein 2 protects mice from aging. / 09.2016 / PubMed / Full text
  • Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians. / 08.2016 / PubMed / Full text
  • Differential modulation of AMPK/PPARα/UCP2 axis in relation to hypertension and aging in the brain, kidneys and heart of two closely related spontaneously hypertensive rat strains. / 07.08.2015 / PubMed / Full text
  • [Genotype and allele frequencies of UCP and PPAR gene families in residents of besieged Leningrad and in the control group]. / 2014 / PubMed
  • Activation of PPAR-γ by pioglitazone attenuates oxidative stress in aging rat cerebral arteries through upregulating UCP2. / 12.2014 / PubMed / Full text
  • Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity. / 06.2014 / PubMed / Full text
  • Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. / 04.2014 / PubMed / Full text

CXCL10[править]

  • Age-related decline of interferon-gamma responses in macrophage impairs satellite cell proliferation and regeneration. / 10.2020 / PubMed / Full text
  • Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. / 07.2019 / PubMed / Full text
  • Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
  • Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor. / 2018 / PubMed / Full text
  • Aged Chinese-origin rhesus macaques infected with SIV develop marked viremia in absence of clinical disease, inflammation or cognitive impairment. / 01.02.2018 / PubMed / Full text
  • Immune senescence and biomarkers profile of Bambuí aged population-based cohort. / 03.2018 / PubMed / Full text
  • Dysregulation of C-X-C motif ligand 10 during aging and association with cognitive performance. / 03.2018 / PubMed / Full text
  • Selected life-extending interventions reduce arterial CXCL10 and macrophage colony-stimulating factor in aged mouse arteries. / 08.2017 / PubMed / Full text
  • Interferon-gamma deficiency protects against aging-related goblet cell loss. / 04.10.2016 / PubMed / Full text
  • Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence. / 07.2016 / PubMed / Full text
  • In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant. / 07.2016 / PubMed / Full text
  • Thinning of the RPE and choroid associated with T lymphocyte recruitment in aged and light-challenged mice. / 2015 / PubMed / Full text
  • CCL2, CXCL8, CXCL9 and CXCL10 serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees. / 12.2017 / PubMed / Full text
  • Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. / 06.2015 / PubMed / Full text
  • Viremic and Virologically Suppressed HIV Infection Increases Age-Related Changes to Monocyte Activation Equivalent to 12 and 4 Years of Aging, Respectively. / 01.05.2015 / PubMed / Full text
  • Increased recruitment of bone marrow-derived cells into the brain associated with altered brain cytokine profile in senescence-accelerated mice. / 04.2016 / PubMed / Full text
  • Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state. / 11.2014 / PubMed / Full text

FAS[править]

  • Five-year change in maximum tongue pressure and physical function in community-dwelling elderly adults. / 09.2020 / PubMed / Full text
  • Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity. / 03.2020 / PubMed / Full text
  • Application of GFR estimation equations in elderly patients with measured GFR below 60 mL/min/1.73 m . / 03.2020 / PubMed / Full text
  • Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes. / 04.2019 / PubMed / Full text
  • Genetic and Environmental Influences on Language Ability in Older Adults: Findings from the Older Australian Twins Study. / 05.2018 / PubMed / Full text
  • Effects of aging on fat deposition and meat quality in Sheldrake duck. / 01.06.2018 / PubMed / Full text
  • Impact of sociodemographic variables on executive functions. / 01-03.2017 / PubMed / Full text
  • Prevalence of Impaired Kidney Function in the German Elderly: Results from the Berlin Aging Study II (BASE-II). / 2017 / PubMed / Full text
  • Multiple category verbal fluency in mild cognitive impairment and correlation with CSF biomarkers for Alzheimer's disease. / 06.2017 / PubMed / Full text
  • Glomerular Filtration Rate in Healthy Living Potential Kidney Donors: A Meta-Analysis Supporting the Construction of the Full Age Spectrum Equation. / 2017 / PubMed / Full text
  • Life Expectancy of People with Fetal Alcohol Syndrome. / 2016 / PubMed
  • Increased susceptibility of CD4 T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels. / 09.10.2015 / PubMed / Full text
  • Systemic Akt1 Deletion after Tumor Onset in p53(-/-) Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration. / 28.07.2015 / PubMed / Full text
  • Impact of loss of NF-κB1, NF-κB2 or c-REL on SLE-like autoimmune disease and lymphadenopathy in Fas(lpr/lpr) mutant mice. / 01.2016 / PubMed / Full text
  • Longitudinal measures of perfluoroalkyl substances (PFAS) in serum of Gullah African Americans in South Carolina: 2003-2013. / 11.2015 / PubMed / Full text
  • White Adipose Tissue Depot-Specific Activity of Lipogenic Enzymes in Response to Fasting and Refeeding in Young and Old Rats. / 2015 / PubMed / Full text
  • Short-term calorie restriction and refeeding differently affect lipogenic enzymes in major white adipose tissue depots of young and old rats. / 02.2014 / PubMed

FH[править]

  • Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study. / 2020 / PubMed / Full text
  • Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia. / 07.2020 / PubMed / Full text
  • Macroscopic hematuria as a risk factor for hypertension in ageing people with hemophilia and a family history of hypertension. / 02.2020 / PubMed / Full text
  • LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis. / 2020 / PubMed / Full text
  • Sex differences in cholesterol levels from birth to 19 years of age may lead to increased cholesterol burden in females with FH. / 05-06.2018 / PubMed / Full text
  • Association between lipoprotein (a) and proprotein convertase substilisin/kexin type 9 in patients with heterozygous familial hypercholesterolemia: A case-control study. / 02.2018 / PubMed / Full text
  • Longitudinal Assessment of Self- and Informant-Subjective Cognitive Complaints in a Sample of Healthy Late-Middle Aged Adults Enriched with a Family History of Alzheimer's Disease. / 09.2017 / PubMed / Full text
  • Diffusion Tensor Imaging Predictors of Episodic Memory Decline in Healthy Elders at Genetic Risk for Alzheimer's Disease. / 11.2016 / PubMed / Full text
  • Familial hypercholesterolaemia reduces the quality of life of patients not reaching treatment targets. / 05.2016 / PubMed
  • Effect of fetal hypothyroidism on tolerance to ischemia-reperfusion injury in aged male rats: Role of nitric oxide. / 01.05.2016 / PubMed / Full text
  • Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment. / 21.09.2015 / PubMed / Full text
  • Impact of family history of alcoholism on glutamine/glutamate ratio in anterior cingulate cortex in substance-naïve adolescents. / 12.2015 / PubMed / Full text
  • Age-Based Differences in the Genetic Determinants of Glycemic Control: A Case of FOXO3 Variations. / 2015 / PubMed / Full text
  • The Mechanism of Ligamentum Flavum Hypertrophy: Introducing Angiogenesis as a Critical Link That Couples Mechanical Stress and Hypertrophy. / 08.2015 / PubMed / Full text
  • Longitudinal measures of perfluoroalkyl substances (PFAS) in serum of Gullah African Americans in South Carolina: 2003-2013. / 11.2015 / PubMed / Full text
  • FDG and Amyloid PET in Cognitively Normal Individuals at Risk for Late-Onset Alzheimer's Disease. / 04.2014 / PubMed / Full text
  • Randomized trial of the ForeseeHome monitoring device for early detection of neovascular age-related macular degeneration. The HOme Monitoring of the Eye (HOME) study design - HOME Study report number 1. / 03.2014 / PubMed / Full text

GDNF[править]

  • GFR-α1 Expression in Substantia Nigra Increases Bilaterally Following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss Following 6-OHDA Nigrostriatal Lesion. / 16.10.2019 / PubMed / Full text
  • The Gender-Biased Effects of Intranasal MPTP Administration on Anhedonic- and Depressive-Like Behaviors in C57BL/6 Mice: the Role of Neurotrophic Factors. / 11.2018 / PubMed / Full text
  • Analysis of neurotrophic and antioxidant factors related to midbrain dopamine neuronal loss and brain inflammation in the cerebrospinal fluid of the elderly. / 09.2018 / PubMed / Full text
  • Glial cell line-derived neurotrophic factor (GDNF) attenuates the peripheral neuromuscular dysfunction without inhibiting the activation of spinal microglia/monocyte. / 09.05.2018 / PubMed / Full text
  • Aging-related limit of exercise efficacy on motor decline. / 2017 / PubMed / Full text
  • The Noradrenergic System of Aged GDNF Heterozygous Mice. / 04.2003 / PubMed / Full text
  • Age-associated decrease in GDNF and its cognate receptor GFRα-1 protein expression in human skin. / 06.2016 / PubMed / Full text
  • Effect of age on expression of spermatogonial markers in bovine testis and isolated cells. / 07.2016 / PubMed / Full text
  • Human neural progenitors differentiate into astrocytes and protect motor neurons in aging rats. / 06.2016 / PubMed / Full text
  • Exercise-Mediated Increase in Nigral Tyrosine Hydroxylase Is Accompanied by Increased Nigral GFR-α1 and EAAC1 Expression in Aging Rats. / 17.02.2016 / PubMed / Full text
  • Mechanisms of Muscle Denervation in Aging: Insights from a Mouse Model of Amyotrophic Lateral Sclerosis. / 09.2015 / PubMed / Full text
  • The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease. / 09.2015 / PubMed / Full text
  • Symptomatic improvement, increased life-span and sustained cell homing in amyotrophic lateral sclerosis after transplantation of human umbilical cord blood cells genetically modified with adeno-viral vectors expressing a neuro-protective factor and a neural cell adhesion molecule. / 2015 / PubMed / Full text
  • Effects of aging on glutamate neurotransmission in the substantia nigra of Gdnf heterozygous mice. / 03.2015 / PubMed / Full text
  • Age and lesion-induced increases of GDNF transgene expression in brain following intracerebral injections of DNA nanoparticles. / 22.01.2015 / PubMed / Full text
  • Astrocytes show reduced support of motor neurons with aging that is accelerated in a rodent model of ALS. / 02.2015 / PubMed / Full text
  • GDNF and GFRα co-receptor family in the developing feline gut. / 09.2014 / PubMed / Full text

KLF4[править]

  • Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1α Activation. / 25.06.2020 / PubMed / Full text
  • Soluble klotho regulates the function of salivary glands by activating KLF4 pathways. / 02.10.2019 / PubMed / Full text
  • Centenarians Overexpress Pluripotency-Related Genes. / 16.08.2019 / PubMed / Full text
  • A SIRT1-centered circuitry regulates breast cancer stemness and metastasis. / 12.2018 / PubMed / Full text
  • miR-10a rejuvenates aged human mesenchymal stem cells and improves heart function after myocardial infarction through KLF4. / 30.05.2018 / PubMed / Full text
  • MYC Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition. / 10.04.2018 / PubMed / Full text
  • Kruppel-like factor 4 regulates keratinocyte senescence. / 05.05.2018 / PubMed / Full text
  • Role of CD133 Molecule in Wnt Response and Renal Repair. / 03.2018 / PubMed / Full text
  • Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence. / 15.10.2017 / PubMed / Full text
  • ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors. / 09.2017 / PubMed / Full text
  • Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. / 01.09.2017 / PubMed / Full text
  • Role of p16 and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells. / 08.2017 / PubMed / Full text
  • Overexpression of KLF4 promotes cell senescence through microRNA-203-survivin-p21 pathway. / 13.09.2016 / PubMed / Full text
  • Adipose-derived stem cells from lean and obese humans show depot specific differences in their stem cell markers, exosome contents and senescence: role of protein kinase C delta (PKCδ) in adipose stem cell niche. / 2016 / PubMed / Full text
  • KLF4 deletion alters gastric cell lineage and induces MUC2 expression. / 09.06.2016 / PubMed / Full text
  • Critical role of the miR-200 family in regulating differentiation and proliferation of neurons. / 06.2015 / PubMed / Full text
  • Oxidative DNA damage causes premature senescence in mouse embryonic fibroblasts deficient for Krüppel-like factor 4. / 09.2015 / PubMed / Full text

LPO[править]

  • [Features of the changes in lipid peroxidation and activity of Na /K -ATPase in the brain of the aged rats in the conditions of two-vessel cerebral ischemia/reperfusion.] / 2019 / PubMed
  • Exercise training initiated at old stage of lifespan attenuates aging-and ovariectomy-induced cardiac and renal oxidative stress: Role of baroreflex. / 09.2019 / PubMed / Full text
  • Tris(1,3-dichloro-2-propyl) phosphate accelerated the aging process induced by the 4-hydroxynon-2-enal response to reactive oxidative species in Caenorhabditis elegans. / 03.2019 / PubMed / Full text
  • Physical Exercise Attenuates Oxidative Stress and Morphofunctional Cerebellar Damages Induced by the Ethanol Binge Drinking Paradigm from Adolescence to Adulthood in Rats. / 2019 / PubMed / Full text
  • [Effect of cryopreserved cord blood nucleated cells on course of pathological processes in progressive aging of brain (experimental study).] / 2018 / PubMed
  • Analysis of Plasma MicroRNAs as Predictors and Biomarkers of Aging and Frailty in Humans. / 2018 / PubMed / Full text
  • ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation. / 20.08.2018 / PubMed / Full text
  • Antioxidant action of grape seed polyphenols and aerobic exercise in improving neuronal number in the hippocampus is associated with decrease in lipid peroxidation and hydrogen peroxide in adult and middle-aged rats. / 01.2018 / PubMed / Full text
  • The antioxidative and anti-aging effects of acidic- and alkalic-extractable mycelium polysaccharides by Agrocybe aegerita (Brig.) Sing. / 01.2018 / PubMed / Full text
  • Aging modifies daily variation of antioxidant enzymes and oxidative status in the hippocampus. / 02.2017 / PubMed / Full text
  • Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes. / 06.2017 / PubMed / Full text
  • An iron-deficient diet during development induces oxidative stress in relation to age and gender in Wistar rats. / 02.2017 / PubMed / Full text
  • Age-Dependent Changes in Na( ),K( )-ATPase Activity and Lipid Peroxidation in Membranes of Erythrocytes during Cardiosclerosis Development in Rats. / 06.2016 / PubMed / Full text
  • Purple sweet potato anthocyanin attenuates fat-induced mortality in Drosophila melanogaster. / 09.2016 / PubMed / Full text
  • n-3 fatty acids effectively improve the reference memory-related learning ability associated with increased brain docosahexaenoic acid-derived docosanoids in aged rats. / 02.2015 / PubMed / Full text
  • Pectinase-treated Panax ginseng extract (GINST) rescues testicular dysfunction in aged rats via redox-modulating proteins. / 05.2014 / PubMed / Full text
  • Antioxidant role of oleuropein on midbrain and dopaminergic neurons of substantia nigra in aged rats. / 2014 / PubMed / Full text

MTR[править]

  • Amide proton transfer-weighted magnetic resonance imaging of human brain aging at 3 Tesla. / 03.2020 / PubMed / Full text
  • One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults. / 12.2019 / PubMed / Full text
  • Test-retest reliability of myelin imaging in the human spinal cord: Measurement errors versus region- and aging-induced variations. / 2018 / PubMed / Full text
  • Alterations in brain white matter contributing to age-related slowing of task switching performance: The role of radial diffusivity and magnetization transfer ratio. / 11.2016 / PubMed / Full text
  • Development and aging of superficial white matter myelin from young adulthood to old age: Mapping by vertex-based surface statistics (VBSS). / 05.2016 / PubMed / Full text
  • Moderate treadmill running exercise prior to tendon injury enhances wound healing in aging rats. / 23.02.2016 / PubMed / Full text
  • Nutritional habits, lifestyle, and genetic predisposition in cardiovascular and metabolic traits in Turkish population. / 06.2016 / PubMed / Full text
  • Age-effects in white matter using associated diffusion tensor imaging and magnetization transfer ratio during late childhood and early adolescence. / 05.2016 / PubMed / Full text
  • Associations between insulin action and integrity of brain microstructure differ with familial longevity and with age. / 2015 / PubMed / Full text
  • An in vivo study on brain microstructure in biological and chronological ageing. / 2015 / PubMed / Full text
  • White matter hyperintensities and normal-appearing white matter integrity in the aging brain. / 02.2015 / PubMed / Full text
  • Structural covariance of superficial white matter in mild Alzheimer's disease compared to normal aging. / 09.2014 / PubMed / Full text
  • Magnetization transfer ratio relates to cognitive impairment in normal elderly. / 2014 / PubMed / Full text
  • Gender, age-related, and regional differences of the magnetization transfer ratio of the cortical and subcortical brain gray matter. / 08.2014 / PubMed / Full text
  • Age independently affects myelin integrity as detected by magnetization transfer magnetic resonance imaging in multiple sclerosis. / 2014 / PubMed / Full text
  • Magnetization transfer imaging for in vivo detection of microstructural tissue changes in aging and dementia: a short literature review. / 2014 / PubMed / Full text
  • Quantitative multi-modal MRI of the Hippocampus and cognitive ability in community-dwelling older subjects. / 04.2014 / PubMed / Full text

NOX4[править]

  • Sestrin2 Attenuates Cellular Senescence by Inhibiting NADPH Oxidase 4 Expression. / 24.11.2020 / PubMed / Full text
  • NADPH Oxidases and Aging Models of Lung Fibrosis. / 2019 / PubMed / Full text
  • Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. / 08.2019 / PubMed / Full text
  • Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
  • Redox Imbalance in Idiopathic Pulmonary Fibrosis: A Role for Oxidant Cross-Talk Between NADPH Oxidase Enzymes and Mitochondria. / 10.11.2019 / PubMed / Full text
  • NADPH oxidase 4 mediates ROS production in radiation-induced senescent cells and promotes migration of inflammatory cells. / 01.2018 / PubMed / Full text
  • Alternative Splicing of NOX4 in the Failing Human Heart. / 2017 / PubMed / Full text
  • Cooperation between p21 and Akt is required for p53-dependent cellular senescence. / 10.2017 / PubMed / Full text
  • Mcl-1 regulates reactive oxygen species via NOX4 during chemotherapy-induced senescence. / 25.04.2017 / PubMed / Full text
  • PPARα activation by MHY908 attenuates age-related renal inflammation through modulation of the ROS/Akt/FoxO1 pathway. / 06.2017 / PubMed / Full text
  • NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis. / 01.2017 / PubMed / Full text
  • NOX4 downregulation leads to senescence of human vascular smooth muscle cells. / 11.10.2016 / PubMed / Full text
  • Reactive oxygen species: The good, the bad, and the enigma. / 07-09.2014 / PubMed / Full text
  • Interferon gamma/NADPH oxidase defense system in immunity and cancer. / 02.2016 / PubMed / Full text
  • NOS1 induces NADPH oxidases and impairs contraction kinetics in aged murine ventricular myocytes. / 09.2015 / PubMed / Full text
  • NOX4 NADPH Oxidase-Dependent Mitochondrial Oxidative Stress in Aging-Associated Cardiovascular Disease. / 20.12.2015 / PubMed / Full text
  • The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4. / 08.2014 / PubMed / Full text

PARP1[править]

  • Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections. / 2019 / PubMed / Full text
  • PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD levels and increasing SIRT1 activity. / 23.08.2018 / PubMed / Full text
  • Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice. / 13.10.2017 / PubMed / Full text
  • Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. / 04.2018 / PubMed / Full text
  • Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. / 2017 / PubMed / Full text
  • The NAD /PARP1/SIRT1 Axis in Aging. / 06.2017 / PubMed / Full text
  • A conserved NAD binding pocket that regulates protein-protein interactions during aging. / 24.03.2017 / PubMed / Full text
  • Melatonin regulates PARP1 to control the senescence-associated secretory phenotype (SASP) in human fetal lung fibroblast cells. / 08.2017 / PubMed / Full text
  • The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence. / 03.03.2017 / PubMed / Full text
  • A serum miRNA profile of human longevity: findings from the Baltimore Longitudinal Study of Aging (BLSA). / 07.11.2016 / PubMed / Full text
  • Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA. / 01.11.2016 / PubMed / Full text
  • Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. / 10.2016 / PubMed / Full text
  • Differential cytotoxicity induced by the Titanium(IV)Salan complex Tc52 in G2-phase independent of DNA damage. / 13.07.2016 / PubMed / Full text
  • All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. / 06.10.2015 / PubMed / Full text
  • SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner. / 2015 / PubMed / Full text
  • RecQ helicases and PARP1 team up in maintaining genome integrity. / 09.2015 / PubMed / Full text
  • Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1. / 03.06.2014 / PubMed / Full text

ADAM10[править]

  • NKG2D Ligand Shedding in Response to Stress: Role of ADAM10. / 2020 / PubMed / Full text
  • Chronic Mild Stress Modified Epigenetic Mechanisms Leading to Accelerated Senescence and Impaired Cognitive Performance in Mice. / 10.02.2020 / PubMed / Full text
  • Removal of p75 Neurotrophin Receptor Expression from Cholinergic Basal Forebrain Neurons Reduces Amyloid-β Plaque Deposition and Cognitive Impairment in Aged APP/PS1 Mice. / 07.2019 / PubMed / Full text
  • 11β-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model. / 12.2018 / PubMed / Full text
  • Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells. / 15.01.2018 / PubMed / Full text
  • microRNA 221 Targets ADAM10 mRNA and is Downregulated in Alzheimer's Disease. / 2018 / PubMed / Full text
  • Human Plasma Thioredoxin-80 Increases With Age and in ApoE Mice Induces Inflammation, Angiogenesis, and Atherosclerosis. / 01.08.2017 / PubMed / Full text
  • Ionizing radiation reduces ADAM10 expression in brain microvascular endothelial cells undergoing stress-induced senescence. / 04.2017 / PubMed / Full text
  • Regulation of Alpha-Secretase ADAM10 [i]In vitro[/i] and [i]In vivo[/i]: Genetic, Epigenetic, and Protein-Based Mechanisms. / 2017 / PubMed / Full text
  • Sideritis spp. Extracts Enhance Memory and Learning in Alzheimer's β-Amyloidosis Mouse Models and Aged C57Bl/6 Mice. / 31.05.2016 / PubMed / Full text
  • Effects of Sesaminol Feeding on Brain Aβ Accumulation in a Senescence-Accelerated Mouse-Prone 8. / 22.06.2016 / PubMed / Full text
  • Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence. / 07.2016 / PubMed / Full text
  • Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice. / 04.2016 / PubMed / Full text
  • Increase of α-Secretase ADAM10 in Platelets Along Cognitively Healthy Aging. / 2016 / PubMed / Full text
  • ADAM10 gene expression in the blood cells of Alzheimer's disease patients and mild cognitive impairment subjects. / 2015 / PubMed / Full text
  • Serum Fragments of Tau for the Differential Diagnosis of Alzheimer's Disease. / 2015 / PubMed / Full text

ALDH2[править]

  • Aldehyde Dehydrogenase 2 (ALDH2) and Aging: Is There a Sensible Link? / 2019 / PubMed / Full text
  • Appropriate dose of ethanol exerts anti-senescence and anti-atherosclerosis protective effects by activating ALDH2. / 30.04.2019 / PubMed / Full text
  • Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue. / 02.2019 / PubMed / Full text
  • Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde. / 02.2019 / PubMed / Full text
  • Aldehyde dehydrogenase 2 deficiency promotes atherosclerotic plaque instability through accelerating mitochondrial ROS-mediated vascular smooth muscle cell senescence. / 01.07.2019 / PubMed / Full text
  • ALDH2 mediates the dose-response protection of chronic ethanol against endothelial senescence through SIRT1/p53 pathway. / 12.10.2018 / PubMed / Full text
  • Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung. / 21.04.2017 / PubMed / Full text
  • Complex inhibition of autophagy by mitochondrial aldehyde dehydrogenase shortens lifespan and exacerbates cardiac aging. / 08.2017 / PubMed / Full text
  • Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence. / 07.2016 / PubMed / Full text
  • Associations Between Alcohol Consumption and Leukocyte Telomere Length Modified by a Common Polymorphism of ALDH2. / 04.2016 / PubMed / Full text
  • Relationships of alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) genotypes with alcohol sensitivity, drinking behavior and problem drinking in Japanese older men. / 05.2016 / PubMed / Full text
  • Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on SIRT1. / 19.01.2016 / PubMed / Full text
  • Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease. / 25.04.2015 / PubMed / Full text
  • Ethanol reduces lifespan, body weight, and serum alanine aminotransferase level of aldehyde dehydrogenase 2 knockout mouse. / 07.2014 / PubMed / Full text
  • Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function. / 06.2014 / PubMed / Full text
  • Targeting aldehyde dehydrogenase 2: new therapeutic opportunities. / 01.2014 / PubMed / Full text

BCR[править]

  • The presence of CLL-associated stereotypic B cell receptors in the normal BCR repertoire from healthy individuals increases with age. / 2019 / PubMed / Full text
  • Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation. / 2019 / PubMed / Full text
  • Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors. / 2018 / PubMed / Full text
  • B cell responses to apoptotic cells in MFG-E8-/- mice. / 2018 / PubMed / Full text
  • Early Generated B-1-Derived B Cells Have the Capacity To Progress To Become Mantle Cell Lymphoma-like Neoplasia in Aged Mice. / 15.07.2018 / PubMed / Full text
  • Mean residual life regression with functional principal component analysis on longitudinal data for dynamic prediction. / 12.2018 / PubMed / Full text
  • NLR Nod1 signaling promotes survival of BCR-engaged mature B cells through up-regulated Nod1 as a positive outcome. / 02.10.2017 / PubMed / Full text
  • Phylogenetic analysis of the human antibody repertoire reveals quantitative signatures of immune senescence and aging. / 31.01.2017 / PubMed / Full text
  • Immunosenescence-Related Transcriptomic and Immunologic Changes in Older Individuals Following Influenza Vaccination. / 2016 / PubMed / Full text
  • 4-methylumbelliferone and imatinib combination enhances senescence induction in chronic myeloid leukemia cell lines. / 02.2017 / PubMed / Full text
  • Hyaluronan oligomers sensitize chronic myeloid leukemia cell lines to the effect of Imatinib. / 04.2016 / PubMed / Full text
  • Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors. / 12.2015 / PubMed / Full text
  • The ageing human B cell repertoire: a failure of selection? / 01.2016 / PubMed / Full text
  • Age stratified comparative analysis of perioperative, functional and oncologic outcomes in patients after robot assisted radical prostatectomy--A propensity score matched study. / 07.2015 / PubMed / Full text
  • Double negative (CD19 IgG IgD-CD27-) B lymphocytes: a new insight from telomerase in healthy elderly, in centenarian offspring and in Alzheimer's disease patients. / 11.2014 / PubMed / Full text
  • Memory B cells form in aged mice despite impaired affinity maturation and germinal center kinetics. / 06.2014 / PubMed / Full text

CD19[править]

  • Sequential treatment with aT19 cells generates memory CAR-T cells and prolongs the lifespan of Raji-B-NDG mice. / 28.01.2020 / PubMed / Full text
  • Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma / 18.11.2019 / PubMed / Full text
  • Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro. / 2018 / PubMed / Full text
  • Innate and adaptive immune dysregulation in critically ill ICU patients. / 05.07.2018 / PubMed / Full text
  • Vitamin D levels correlate with lymphocyte subsets in elderly patients with age-related diseases. / 16.05.2018 / PubMed / Full text
  • Normal variation of bone marrow B-cell precursors according to age - reference ranges for studies in myelodysplastic syndromes in Brazil. / 09.2018 / PubMed / Full text
  • Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses. / 17.08.2017 / PubMed / Full text
  • Different therapeutic effects of cells derived from human amniotic membrane on premature ovarian aging depend on distinct cellular biological characteristics. / 27.07.2017 / PubMed / Full text
  • Immune biomarkers in older adults: Role of physical activity. / 2017 / PubMed / Full text
  • A lifetime aging study of human CD19 transgenic mice. / 06.2017 / PubMed / Full text
  • Age-related arterial immune cell infiltration in mice is attenuated by caloric restriction or voluntary exercise. / 08.2018 / PubMed / Full text
  • Alterations in B-cell subsets in pediatric patients with early atopic dermatitis. / 07.2017 / PubMed / Full text
  • Perturbed hematopoiesis in mice lacking ATMIN. / 20.10.2016 / PubMed / Full text
  • Effects of Ageing on the Immune System: Infants to Elderly. / 04.2016 / PubMed / Full text
  • Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease. / 11.2015 / PubMed / Full text
  • [Effects of soluble egg antigen and adult worm antigen of Schistosoma japonicum on differentiation of effector B cells of mice]. / 10.2013 / PubMed

CDK2[править]

  • p57 is a master regulator of human adipose derived stem cell quiescence and senescence. / 04.2020 / PubMed / Full text
  • Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential. / 22.05.2020 / PubMed / Full text
  • Cyclin-Dependent Kinase 2 in Cellular Senescence and Cancer. A Structural and Functional Review. / 2019 / PubMed / Full text
  • Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes. / 01.05.2019 / PubMed / Full text
  • Relationship between intermuscular adipose tissue infiltration and myostatin before and after aerobic exercise training. / 01.09.2018 / PubMed / Full text
  • Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line. / 2018 / PubMed / Full text
  • Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress. / 20.02.2018 / PubMed / Full text
  • Inhibition of CIP2A attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma. / 08.01.2018 / PubMed / Full text
  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
  • Pneumolysin induces cellular senescence by increasing ROS production and activation of MAPK/NF-κB signal pathway in glial cells. / 04.2017 / PubMed / Full text
  • The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging. / 12.2016 / PubMed / Full text
  • A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1. / 27.09.2016 / PubMed / Full text
  • Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. / 09.2016 / PubMed / Full text
  • Double staining of β-galactosidase with fibrosis and cancer markers reveals the chronological appearance of senescence in liver carcinogenesis induced by diethylnitrosamine. / 22.01.2016 / PubMed / Full text
  • Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue. / 09.2015 / PubMed / Full text
  • Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells. / 2015 / PubMed / Full text

CDK6[править]

  • Saturated Fatty Acids Promote Hepatocytic Senecence through Regulation of miR-34a/Cyclin-Dependent Kinase 6. / 24.09.2020 / PubMed / Full text
  • Hepatoprotective effects of hydroxysafflor yellow A in D-galactose-treated aging mice. / 15.08.2020 / PubMed / Full text
  • Anti-cell growth and anti-cancer stem cell activity of the CDK4/6 inhibitor palbociclib in breast cancer cells. / 05.2020 / PubMed / Full text
  • Compromising the constitutive p16 expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence. / 04.2020 / PubMed / Full text
  • Palbociclib Effectively Halts Proliferation but Fails to Induce Senescence in Patient-Derived Glioma Stem Cells. / 11.2019 / PubMed / Full text
  • Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth. / 01.05.2019 / PubMed / Full text
  • Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line. / 2018 / PubMed / Full text
  • Preclinical characterization of abemaciclib in hormone receptor positive breast cancer. / 19.09.2017 / PubMed / Full text
  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
  • Genome-Wide Overexpression Screen Identifies Genes Able to Bypass p16-Mediated Senescence in Melanoma. / 03.2017 / PubMed / Full text
  • p16INK4a suppresses BRCA1-deficient mammary tumorigenesis. / 20.12.2016 / PubMed / Full text
  • A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1. / 27.09.2016 / PubMed / Full text
  • CDK4-CDK6 inhibitors induce autophagy-mediated degradation of DNMT1 and facilitate the senescence antitumor response. / 02.10.2016 / PubMed / Full text
  • Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. / 10.2016 / PubMed / Full text
  • MicroRNA-33 promotes the replicative senescence of mouse embryonic fibroblasts by suppressing CDK6. / 13.05.2016 / PubMed / Full text
  • MiR-506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer. / 07.2014 / PubMed / Full text

CX3CR1[править]

  • Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism. / 04.2020 / PubMed / Full text
  • Muscle Injury Induces Postoperative Cognitive Dysfunction. / 17.02.2020 / PubMed / Full text
  • Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text
  • Surgical Trauma Exacerbates Cognitive Deficits and Neuroinflammation in Aged Rats: The Role of CX3CL1-CX3CR1 Signaling. / 01.08.2018 / PubMed / Full text
  • Repopulating retinal microglia restore endogenous organization and function under CX3CL1-CX3CR1 regulation. / 03.2018 / PubMed / Full text
  • Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging. / 05.2018 / PubMed / Full text
  • Microglia and Aging: The Role of the TREM2-DAP12 and CX3CL1-CX3CR1 Axes. / 22.01.2018 / PubMed / Full text
  • Strain specificities in age-related changes in mechanisms promoting and controlling rat spinal cord damage in experimental autoimmune encephalomyelitis. / 01.2018 / PubMed / Full text
  • Sex as a determinant of age-related changes in rat spinal cord inflammation-oxidation state. / 10.2017 / PubMed / Full text
  • Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists. / 15.08.2017 / PubMed / Full text
  • Transcriptomic analysis of purified human cortical microglia reveals age-associated changes. / 08.2017 / PubMed / Full text
  • Phenotypic characteristics of aged CD4 CD28 T lymphocytes are determined by changes in the whole-genome DNA methylation pattern. / 04.2017 / PubMed / Full text
  • Age exacerbates the CCR2/5-mediated neuroinflammatory response to traumatic brain injury. / 18.04.2016 / PubMed / Full text
  • Alterations in Monocyte Phenotypes and Functions after a Hip Fracture in Elderly Individuals: A 6-Month Longitudinal Study. / 2016 / PubMed / Full text
  • Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques. / 29.01.2015 / PubMed / Full text
  • Alterations to the frequency and function of peripheral blood monocytes and associations with chronic disease in the advanced-age, frail elderly. / 2014 / PubMed / Full text

ECD[править]

  • Outcome of Descemet Membrane Endothelial Keratoplasty Using Corneas from Donors ≥80 Years of Age. / 03.2020 / PubMed / Full text
  • The occurrence and dynamics of polychlorinated hydrocarbons in roe deer ([i]Capreolus capreolus[/i]) in South-western Slovakia. / 2019 / PubMed / Full text
  • Corneal thickness, endothelial cell density, and morphological and morphometric features of corneal endothelial cells in goats. / 10.2018 / PubMed / Full text
  • Endothelial cell density and characterization of corneal endothelial cells in the Tawny Owl (Strix aluco) using specular microscopy. / 03.2019 / PubMed / Full text
  • An autopsy case report: Differences in radiological images correlate with histology in Erdheim-Chester disease. / 06.2018 / PubMed / Full text
  • Community-based trials of mobile solutions for the detection and management of cognitive decline. / 06.2017 / PubMed / Full text
  • Evaluating age-related change in lip somatosensation using somatosensory evoked magnetic fields. / 2017 / PubMed / Full text
  • A novel method for examining corneal endothelial cell morphology in infants. / 06.2017 / PubMed / Full text
  • Analyses of Factors Affecting Endothelial Cell Density in an Eye Bank Corneal Donor Database. / 09.2016 / PubMed / Full text
  • Morphological Abnormalities of Schlemm's Canal in Primary Open-Angle Glaucoma From the Aspect of Aging. / 02.2016 / PubMed / Full text
  • [TEMPORAL ORDER DETERIORATION AND CIRCADIAN DISRUPTION WITH AGE]. / 2015 / PubMed
  • Age-Dependent Changes of the Temporal Order--Causes and Treatment. / 2016 / PubMed / Full text
  • Pathogenesis of endothelial cell dysfunction in chronic kidney disease: a retrospective and what the future may hold. / 06.2015 / PubMed / Full text
  • Specular microscopy to determine corneal endothelial cell morphology and morphometry in chinchillas (Chinchilla lanigera) in vivo. / 01.2015 / PubMed / Full text
  • Oncogene-induced senescence as a new mechanism of disease: the paradigm of erdheim-chester disease. / 2014 / PubMed / Full text
  • Comparison of endothelial cell density of organ cultured corneas with cornea donor study. / 06.2014 / PubMed / Full text

HDAC1[править]

  • HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease. / 18.05.2020 / PubMed / Full text
  • Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. / 04.2019 / PubMed / Full text
  • Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies. / 20.10.2018 / PubMed / Full text
  • Acetylation of PGC1α by Histone Deacetylase 1 Downregulation Is Implicated in Radiation-Induced Senescence of Brain Endothelial Cells. / 16.05.2019 / PubMed / Full text
  • Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri. / 09.2018 / PubMed / Full text
  • Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-HDAC1-mediated regulation of autophagy. / 06.2018 / PubMed / Full text
  • Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment. / 30.05.2017 / PubMed / Full text
  • Epigallocatechin gallate reverses cTnI-low expression-induced age-related heart diastolic dysfunction through histone acetylation modification. / 10.2017 / PubMed / Full text
  • Emerging roles for histone deacetylases in age-related muscle atrophy. / 27.10.2016 / PubMed / Full text
  • [i]Rpd3[/i] interacts with insulin signaling in [i]Drosophila[/i] longevity extension. / 14.11.2016 / PubMed / Full text
  • Expression of non-secreted IL-4 is associated with HDAC inhibitor-induced cell death, histone acetylation and c-Jun regulation in human gamma/delta T-cells. / 04.10.2016 / PubMed / Full text
  • The effects of Rpd3 on fly metabolism, health, and longevity. / 15.12.2016 / PubMed / Full text
  • Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations. / 23.02.2016 / PubMed / Full text
  • Scopoletin has a potential activity for anti-aging via autophagy in human lung fibroblasts. / 15.03.2015 / PubMed / Full text
  • De-regulated expression of the BRG1 chromatin remodeling factor in bone marrow mesenchymal stromal cells induces senescence associated with the silencing of NANOG and changes in the levels of chromatin proteins. / 2015 / PubMed / Full text
  • Lysine deacetylases regulate the heat shock response including the age-associated impairment of HSF1. / 10.04.2015 / PubMed / Full text

IL10[править]

  • The beneficial effect of physical exercise on inflammatory makers in older individuals. / 06.06.2020 / PubMed / Full text
  • Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14 , and TAU3 transcript expression and contribute to cognitive decline. / 10.2019 / PubMed / Full text
  • Dietary Spray-Dried Porcine Plasma Prevents Cognitive Decline in Senescent Mice and Reduces Neuroinflammation and Oxidative Stress. / 01.02.2020 / PubMed / Full text
  • Age-dependent hepatic alterations induced by a high-fat high-fructose diet. / 05.2019 / PubMed / Full text
  • [i]Lactobacillus paracasei[/i] PS23 decelerated age-related muscle loss by ensuring mitochondrial function in SAMP8 mice. / 29.01.2019 / PubMed / Full text
  • Inflammatory cytokines and immune system modulation by aerobic versus resisted exercise training for elderly. / 03.2018 / PubMed / Full text
  • Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. / 2018 / PubMed / Full text
  • Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia. / 01.01.2018 / PubMed / Full text
  • The role of gender and labour status in immunosenescence of 65 Polish population. / 08.2017 / PubMed / Full text
  • Serum Immune Mediators Independently Associate with Atherosclerosis in the Left (But Not Right) Carotid Territory of Older Individuals. / 12.2016 / PubMed / Full text
  • IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis. / 11.08.2015 / PubMed / Full text
  • Development of depressive symptoms post hip fracture is associated with altered immunosuppressive phenotype in regulatory T and B lymphocytes. / 02.2016 / PubMed / Full text
  • LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING. / 06.2015 / PubMed
  • The effect of astaxanthin on the aging rat brain: gender-related differences in modulating inflammation. / 30.01.2016 / PubMed / Full text
  • Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults. / 10.2014 / PubMed / Full text
  • Oral delivery of glutamic acid decarboxylase (GAD)-65 and IL10 by Lactococcus lactis reverses diabetes in recent-onset NOD mice. / 08.2014 / PubMed / Full text

INS[править]

  • Melatonin protects INS-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity. / 03.07.2020 / PubMed / Full text
  • Nicotine triggers islet β cell senescence to facilitate the progression of type 2 diabetes. / 08.2020 / PubMed / Full text
  • Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading. / 05.2020 / PubMed / Full text
  • Insulin-like peptides and the mTOR-TFEB pathway protect [i]Caenorhabditis elegans[/i] hermaphrodites from mating-induced death. / 08.07.2019 / PubMed / Full text
  • The Maghreb demographic transition: Tunisia case study. / 10-11.2018 / PubMed
  • Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis. / 02.2019 / PubMed / Full text
  • A functional study of all 40 [i]Caenorhabditis elegans[/i] insulin-like peptides. / 26.10.2018 / PubMed / Full text
  • The anti-aging protein Klotho is induced by GABA therapy and exerts protective and stimulatory effects on pancreatic beta cells. / 02.12.2017 / PubMed / Full text
  • Increase of Calcium Sensing Receptor Expression Is Related to Compensatory Insulin Secretion during Aging in Mice. / 2016 / PubMed / Full text
  • Food-derived sensory cues modulate longevity via distinct neuroendocrine insulin-like peptides. / 01.05.2016 / PubMed / Full text
  • Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of INS-1 cells through Pim-1. / 2016 / PubMed
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