Aging genes 1-2: различия между версиями
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* [[Aging genes | * [[Aging genes 100|Genes with 100 and more publications]] | ||
* [[Aging genes | * [[Aging genes 60-99|Genes with 60-99 publications]] | ||
* [[Aging genes 30-59|Genes with 30-59 publications]] | |||
* [[Aging genes 10-29|Genes with 10-29 publications]] | |||
* [[Aging genes 3-9|Genes with 3-9 publications]] | |||
* [[Aging genes 1-2|Genes with 1-2 publications]] | |||
== | ==SOCS1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. | ||
|date= | |date=06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30656452 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/s10695-018-0607-9 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes. | ||
|date= | |date=28.10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560 | ||
}} | }} | ||
== | ==ATG9A== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[SIRT1]] protects cochlear hair cell and delays age-related hearing loss via autophagy. | ||
|date= | |date=08.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170533 | ||
|full-text-url=https://sci-hub.do/10.1016/j. | |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.04.003 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Activation of miR-34a impairs autophagic flux and promotes cochlear cell death via repressing [[ATG9A]]: implications for age-related hearing loss. | ||
|date= | |date=05.10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28981097 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680584 | ||
}} | }} | ||
== | ==LAT2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Blood glucose, amino acid profiles and nutrient transporter gene expressions in the small intestine of low and normal birthweight piglets during the early suckling period. | ||
|date=05. | |date=05.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971346 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.tvjl.2019.02.006 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Skeletal muscle: from birth to old age, routes to mechanical and metabolic failure. | ||
|date= | |date=2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29099099 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.24875/GMM.17000008 | ||
}} | }} | ||
== | ==ID1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Commentary on Some Recent Theses Relevant to Combating Aging: April 2019. | ||
|date= | |date=04.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30957657 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1089/rej.2019.2201 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras. | ||
|date= | |date=12.09.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847931 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603998 | ||
}} | }} | ||
== | ==OAT== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Opioid agonist treatment reduces losses in quality of life and quality-adjusted life expectancy in heroin users: Evidence from real world data. | ||
|date=01. | |date=01.08.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247504 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.drugalcdep.2019.05.003 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats. | ||
|date=02. | |date=02.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712161 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/s13105-019-00663-x | ||
}} | }} | ||
== | ==ERBB2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The biological age linked to oxidative stress modifies breast cancer aggressiveness. | ||
|date=05. | |date=20.05.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29550329 | ||
|full-text-url=https://sci-hub.do/10.1016/j. | |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.03.012 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Identification of human age-associated gene co-expressions in functional modules using liquid association. | ||
|date=01. | |date=02.01.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416677 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787419 | ||
}} | }} | ||
== | ==NDNF== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of neuron-derived neurotrophic factor on rejuvenation of human adipose-derived stem cells for cardiac repair after myocardial infarction. | ||
|date= | |date=09.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287219 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714174 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury. | ||
|date= | |date=12.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30062183 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059002 | ||
}} | }} | ||
== | ==NECTIN2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. | ||
|date=10. | |date=08.10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Apolipoprotein E region molecular signatures of Alzheimer's disease. | ||
|date= | |date=08.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797398 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052488 | ||
}} | }} | ||
== | ==NDUFB8== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. | ||
|date= | |date=23.05.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29882895 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032417 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions. | ||
|date= | |date=06.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29802507 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060193 | ||
}} | }} | ||
== | ==HSF2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. | ||
|date= | |date=15.04.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Nutrition and water temperature regulate the expression of heat-shock proteins in golden pompano larvae (Trachinotus ovata, Limmaeus 1758). | ||
|date= | |date=04.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30397841 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s10695-018-0578-x | ||
}} | }} | ||
== | ==IQGAP1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[IQGAP1]]-dysfunction leads to induction of senescence in human vascular smooth muscle cells. | ||
|date= | |date=09.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592713 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111295 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Hyaluronan-binding protein 1 (HABP1) overexpression triggers induction of senescence in fibroblasts cells. | ||
|date= | |date=06.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32068317 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1002/cbin.11326 | ||
}} | }} | ||
== | ==PAK1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating [[PAK1]] at nM levels. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760342 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.5582/ddt.2018.01018 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic [[PAK1]]-blockers/longevity-promoters for cancer therapy. | ||
|date= | |date=15.12.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814374 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.ejmech.2017.07.043 | ||
}} | }} | ||
== | ==GNRH1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | ||
|date= | |date=15.11.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Elucidating the genetic architecture of reproductive ageing in the Japanese population. | ||
|date=05. | |date=17.05.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29773799 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958096 | ||
}} | }} | ||
== | ==SORL1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study. | ||
|date= | |date=05.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706571 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608707 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481 | ||
}} | }} | ||
== | ==CISD2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[CISD2]] Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells-As a Potential Therapeutic Target for Neurodegenerative Dementia. | ||
|date= | |date=2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33005144 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479185 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Protective Effects of [[CISD2]] and Influence of Curcumin on [[CISD2]] Expression in Aged Animals and Inflammatory Cell Model. | ||
|date= | |date=25.03.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30934593 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470567 | ||
}} | }} | ||
== | ==MAPKAPK2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. | ||
|date= | |date=03.12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31801093 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980792 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Cell fate regulation by reticulon-4 in human prostate cancers. | ||
|date= | |date=07.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1002/jcp.27704 | ||
}} | }} | ||
== | ==RPS6== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Regulation of Amino Acid Transporters and Sensors in Response to a High protein Diet: A Randomized Controlled Trial in Elderly Men. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30932134 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/s12603-019-1171-4 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107. | ||
|date= | |date=08.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016 | ||
}} | }} | ||
== | ==NNMT== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle. | ||
|date= | |date=05.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753815 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469996 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy. | ||
|date= | |date=09.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30192747 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191153 | ||
}} | }} | ||
== | ==SPARCL1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment. | ||
|date= | |date=18.06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[SPARCL1]] Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154276 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934753 | ||
}} | }} | ||
== | ==IRF7== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood. | ||
|date= | |date=14.01.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. | ||
|date= | |date=06.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062 | ||
}} | }} | ||
== | ==RGN== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29675370 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902356 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of supplementation of recombinant Regucalcin in extender on cryopreservation of spermatozoa of water buffalo (Bubalus bubalis). | ||
|date= | |date=11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782859 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1002/mrd.22873 | ||
}} | }} | ||
== | ==MCM7== | ||
* {{medline-title | * {{medline-title | ||
|title=[[ | |title=Changes in [[MCM2]]-7 proteins at senescence. | ||
|date= | |date=27.07.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1266/ggs.18-00062 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma. | ||
|date= | |date=08.01.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329 | ||
|full-text-url=https://sci-hub.do/10.1016/j. | |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124 | ||
}} | }} | ||
== | ==AQP1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Blue Light Induces Down-Regulation of Aquaporin 1, 3, and 9 in Human Keratinocytes. | ||
|date= | |date=03.11.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400272 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262559 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title=[ | |title=[Age-related changes of water transport by corneal endothelial cells in rats.] | ||
|date= | |date=2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322730 | ||
}} | }} | ||
== | ==EN1== | ||
* {{medline-title | * {{medline-title | ||
|title=[[ | |title=Electrochemically detecting DNA methylation in the [[EN1]] gene promoter: implications for understanding ageing and disease. | ||
|date= | |date=27.11.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33135722 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670582 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The role of DNA methylation in ageing and cancer. | ||
|date= | |date=11.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29708096 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1017/S0029665118000150 | ||
}} | }} | ||
== | ==PPID== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population. | ||
|date=2020 | |date=03.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32058159 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.vetimm.2020.110013 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Epidemiology of pituitary pars intermedia dysfunction: A systematic literature review of clinical presentation, disease prevalence and risk factors. | ||
|date= | |date=05.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29704935 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.tvjl.2018.03.002 | ||
}} | }} | ||
== | ==ADH5== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Can Serum Nitrosoproteome Predict Longevity of Aged Women? | ||
|date= | |date=27.11.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33260845 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731247 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Denitrosylate and live longer: how [[ADH5]]/GSNOR links mitophagy to aging. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30029585 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103690 | ||
}} | }} | ||
== | ==LTB== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA + DHA. | ||
|date= | |date=06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30535619 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s10753-018-0949-6 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis. | ||
|date= | |date=11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803166 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.07.043 | ||
}} | }} | ||
== | ==TRH== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats. | ||
|date= | |date=15.03.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29305326 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.toxlet.2017.12.029 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of dietary carbohydrates and time of year on ACTH and cortisol concentrations in adult and aged horses. | ||
|date= | |date=04.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195115 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.domaniend.2017.10.005 | ||
}} | }} | ||
== | ==GLS== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography. | ||
|date= | |date=15.07.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29784576 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.amjcard.2018.03.355 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Future Perspectives for Management of Stage A Heart Failure. | ||
|date= | |date=01.07.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731506 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055033 | ||
}} | }} | ||
== | ==CLC== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Impact of Intervention to Improve Nursing Home Resident-Staff Interactions and Engagement. | ||
|date= | |date=13.07.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718195 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455946 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of cholesterol loaded cyclodextrin on semen cryopreservation of Aksaray Malakli shepherd dogs of different ages. | ||
|date= | |date=06.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29699920 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2018.04.068 | ||
}} | }} | ||
== | ==RAG1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=T cell senescence accelerates Angiotensin II-induced target organ damage. | ||
|date= | |date=12.02.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32049355 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1093/cvr/cvaa032 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Aged murine hematopoietic stem cells drive aging-associated immune remodeling. | ||
|date= | |date=09.08.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891535 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137572 | ||
}} | }} | ||
== | ==HLA-C== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | ||
|date= | |date=10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. | ||
|date= | |date=2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243 | ||
}} | }} | ||
== | ==WFS1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila. | ||
|date= | |date=01.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29357349 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794194 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A nonsynonymous mutation in the [[WFS1]] gene in a Finnish family with age-related hearing impairment. | ||
|date= | |date=11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28974383 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.heares.2017.09.013 | ||
}} | }} | ||
== | ==PLIN2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Cardiac overexpression of perilipin 2 induces atrial steatosis, connexin 43 remodeling, and atrial fibrillation in aged mice. | ||
|date=12.2019 | |date=01.12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31661297 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957375 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[HDAC6]] Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of [[PLIN2]] in Drosophila. | ||
|date= | |date=09.10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28966044 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.devcel.2017.09.001 | ||
}} | }} | ||
== | ==CCL24== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Anserine/Carnosine Supplementation Suppresses the Expression of the Inflammatory Chemokine [[CCL24]] in Peripheral Blood Mononuclear Cells from Elderly People. | ||
|date= | |date=31.10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088099 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707671 | ||
}} | }} | ||
== | ==TAS2R16== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Taste receptor polymorphisms and longevity: a systematic review and meta-analysis. | ||
|date= | |date=10.11.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33170488 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/s40520-020-01745-3 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Taste receptors, innate immunity and longevity: the case of [[TAS2R16]] gene. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30833980 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387736 | ||
}} | }} | ||
== | ==B4GALT1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Expression of β-1,4-galactosyltransferases during Aging in Caenorhabditis elegans. | ||
|date= | |date=2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33171474 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1159/000510722 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Glycobiology of Aging. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30779020 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/978-981-13-2835-0_17 | ||
}} | }} | ||
== | ==FGFR4== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[FGFR4]] Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. | ||
|date= | |date=14.10.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066597 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602396 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The Klotho proteins in health and disease. | ||
|date= | |date=01.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3 | ||
}} | }} | ||
== | ==NAV2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Genetic associations with age of menopause in familial longevity. | ||
|date= | |date=10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis. | ||
|date= | |date=07.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205 | ||
}} | }} | ||
== | ==ANK1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Alzheimer's Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in [i]Drosophila[/i]. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31244615 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581016 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | ||
|date= | |date=25.07.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | ||
}} | }} | ||
== | ==COL3A1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. | ||
|date= | |date=21.12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31864349 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925900 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts. | ||
|date= | |date=06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890563 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553930 | ||
}} | }} | ||
== | ==ATP7A== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Adipocyte-specific disruption of ATPase copper transporting α in mice accelerates lipoatrophy. | ||
|date=2019 | |date=12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396659 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s00125-019-4966-2 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=TAp73 regulates [[ATP7A]]: possible implications for ageing-related diseases. | ||
|date= | |date=08.12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530920 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326685 | ||
}} | }} | ||
== | ==TPO== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Megakaryocytes promote osteoclastogenesis in aging. | ||
|date=2020 | |date=07.07.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634116 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425434 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex-independent) NOD.H2 mice. | ||
|date=04. | |date=04.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566234 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422661 | ||
}} | }} | ||
== | ==HAS1== | ||
* {{medline-title | * {{medline-title | ||
|title=A | |title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. | ||
|date= | |date=20.06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. | ||
|date= | |date=01.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7 | ||
}} | }} | ||
== | ==TIMELESS== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Loss of circadian protein [[TIMELESS]] accelerates the progression of cellular senescence. | ||
|date= | |date=18.09.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30100061 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.040 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Clock gene expression and locomotor activity predict death in the last days of life in Drosophila melanogaster. | ||
|date= | |date=09.08.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30093652 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085321 | ||
}} | }} | ||
== | ==PROC== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation. | ||
|date= | |date=15.04.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633180 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157190 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effects of feeding frequency of an elevated plane of milk replacer and calf age on behavior, and glucose and insulin kinetics in male Holstein calves. | ||
|date= | |date=07.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30419975 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1017/S175173111800294X | ||
}} | }} | ||
== | ==FLT1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | ||
|date= | |date=15.11.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | ||
|full-text-url=https://sci-hub.do/10.1016/j. | |full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. | ||
|date= | |date=08.10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033 | ||
}} | }} | ||
== | ==IGFBP1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Role of [[IGFBP1]] in the senescence of vascular endothelial cells and severity of aging‑related coronary atherosclerosis. | ||
|date= | |date=11.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545483 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777673 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age. | ||
|date= | |date=04.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781 | ||
}} | }} | ||
== | ==NLRC4== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Hyperglycemia-induced inflamm-aging accelerates gingival senescence via [[NLRC4]] phosphorylation. | ||
|date= | |date=06.12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31676687 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901307 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Contribution of the inflammasome to inflammaging. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30473634 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240324 | ||
}} | }} | ||
== | ==PTBP1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. | ||
|date= | |date=11.12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[PTBP1]]-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. | ||
|date= | |date=09.07.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990503 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048363 | ||
}} | }} | ||
== | ==LSR== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-related changes in regiospecific expression of Lipolysis Stimulated Receptor ([[LSR]]) in mice brain. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31233547 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590887 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title=The | |title=Discriminating Alzheimer's disease progression using a new hippocampal marker from T1-weighted MRI: The local surface roughness. | ||
|date= | |date=01.04.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451343 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865478 | ||
}} | }} | ||
== | ==MLH1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The somatic mutation landscape of the human body. | ||
|date= | |date=24.12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31874648 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930685 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. | ||
|date= | |date=25.02.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1002/jcb.28417 | ||
}} | }} | ||
== | ==DISC1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-Related Changes in Topological Degradation of White Matter Networks and Gene Expression in Chronic Schizophrenia. | ||
|date= | |date=11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28946750 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695754 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice. | ||
|date= | |date=19.09.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701 | ||
}} | }} | ||
== | ==RAN== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Rapid automatized naming ([[RAN]]): effects of aging on a predictor of reading skill. | ||
|date=08 | |date=17.08.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32799742 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1080/13825585.2020.1806987 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=SCA8 [[RAN]] polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F. | ||
|date= | |date=01.10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206144 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166133 | ||
}} | }} | ||
== | ==SRR== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Mediterranean diet and its components in relation to all-cause mortality: meta-analysis. | ||
|date= | |date=11.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30401007 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1017/S0007114518002593 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Genetic Biomarkers on Age-Related Cognitive Decline. | ||
|date= | |date=2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307 | ||
}} | }} | ||
== | ==MIF== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice. | ||
|date= | |date=09.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31381889 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718337 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Macrophage migration inhibitory factor knockdown inhibit viability and induce apoptosis of PVM/Ms. | ||
|date= | |date=12.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28990052 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779918 | ||
}} | }} | ||
== | ==GSTA4== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue. | ||
|date= | |date=02.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472277 | ||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.013 | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | ||
|date= | |date=12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | ||
}} | }} | ||
== | ==MCM2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Trophoblast type-specific expression of senescence markers in the human placenta. | ||
|date= | |date=15.09.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327484 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.placenta.2019.06.377 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Changes in [[MCM2]]-7 proteins at senescence. | ||
|date= | |date=27.07.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1266/ggs.18-00062 | ||
}} | }} | ||
== | ==RNF8== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Expression of [[RNF8]] on cochlear apoptosis and aging in mice of different ages. | ||
|date= | |date=03-Apr,.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915826 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Function of RAD6B and [[RNF8]] in spermatogenesis. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825854 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884393 | ||
}} | }} | ||
== | ==NOTCH3== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Whole-Exome Sequencing of an Exceptional Longevity Cohort. | ||
|date= | |date=16.08.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. | ||
|date= | |date=06.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 | ||
}} | }} | ||
== | ==AGO2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability. | ||
|date= | |date=06.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=miRNA processing gene polymorphisms, blood DNA methylation age and long-term ambient PM exposure in elderly men. | ||
|date= | |date=12.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29106301 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704092 | ||
}} | }} | ||
== | ==LATS2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. | ||
|date=2019 | |date=25.06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis. | ||
|date= | |date=03.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607 | ||
}} | }} | ||
== | ==CTLA4== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Horticultural Therapy Reduces Biomarkers of Immunosenescence and Inflammaging in Community-Dwelling Older Adults: A Feasibility Pilot Randomized Controlled Trial. | ||
|date= | |date=18.10.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33070170 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1093/gerona/glaa271 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[Efficacy and toxicity of immune checkpoint inhibitors in elderly patients - 5th edition of the congress of pharmacology of anticancer drugs]. | ||
|date= | |date=12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30471959 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.bulcan.2018.10.004 | ||
}} | }} | ||
== | ==SESN2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Copy Number Alterations in Papillary Thyroid Carcinomas: Does Loss of [i][[SESN2]][/i] Have a Role in Age-related Different Prognoses? | ||
|date= | |date=09-10.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32859642 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472442 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea. | ||
|date= | |date=11.10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28818524 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605466 | ||
}} | }} | ||
== | ==ZEB1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]]. | ||
|date= | |date=12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating [[DNMT1]] via [[ZEB1]]. | ||
|date= | |date=16.02.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29466247 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842848 | ||
}} | }} | ||
== | ==CLPP== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging. | ||
|date= | |date=02.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30691623 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.11.048 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Mitochondrial unfolded protein response gene Clpp is required to maintain ovarian follicular reserve during aging, for oocyte competence, and development of pre-implantation embryos. | ||
|date= | |date=08.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29851234 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052477 | ||
}} | }} | ||
== | ==BNIP3== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. | ||
|date= | |date=01.10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training. | ||
|date= | |date=01.10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030137 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.011 | ||
}} | }} | ||
== | ==CSRP1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[FOXO3]], a Molecular Search for the Fountain of Youth. | ||
|date= | |date=07.03.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30849363 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.stem.2019.02.008 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[FOXO3]]-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. | ||
|date= | |date=07.03.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661960 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.stem.2018.12.002 | ||
}} | }} | ||
== | ==BCL6== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation. | ||
|date= | |date=01.07.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32452837 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324201 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation. | ||
|date= | |date=08.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640 | ||
}} | }} | ||
== | ==GRK5== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone. | ||
|date= | |date=01.05.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31043680 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494869 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[GRK5]] - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30618771 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304357 | ||
}} | }} | ||
== | ==MCL1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[MCL1]] gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway. | ||
|date= | |date=01.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30296359 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1002/iub.1944 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress. | ||
|date= | |date=10.08.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741 | ||
}} | }} | ||
== | ==COPE== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the [[COPE]]-study. | ||
|date=2020 | |date=09.04.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272897 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147053 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Falls self-efficacy and falls incidence in community-dwelling older people: the mediating role of coping. | ||
|date= | |date=05.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29113615 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1017/S1041610217002319 | ||
}} | }} | ||
== | ==L1CAM== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression. | ||
|date=09. | |date=12.09.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31510944 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739972 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Induction, regulation and roles of neural adhesion molecule [[L1CAM]] in cellular senescence. | ||
|date= | |date=28.03.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615539 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892697 | ||
}} | }} | ||
== | ==MMP3== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging. | ||
|date= | |date=14.11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Identification of a pyridine derivative inducing senescence in ovarian cancer cell lines via P21 activation. | ||
|date= | |date=05.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143360 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1111/1440-1681.12891 | ||
}} | }} | ||
== | ==INSL3== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of Thyroxine Replacement on Leydig Cell and Sertoli Cell Function in Men with Hypothyroidism. | ||
|date=2020 | |date=05-06.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33083267 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539029 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age related and seasonal changes of plasma concentrations of insulin-like peptide 3 and testosterone from birth to early-puberty in Thoroughbred male horses. | ||
|date= | |date=01.07.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31029851 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2019.04.014 | ||
}} | }} | ||
== | ==CYP1A1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population. | ||
|date= | |date=10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31522824 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2019.08.010 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in [[CYP1A1]]-overexpressing breast cancer cells. | ||
|date= | |date=15.12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448188 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.bmc.2018.11.013 | ||
}} | }} | ||
== | ==POSTN== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals [[POSTN]] As a New Element in Proline Metabolic Disorder. | ||
|date= | |date=12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574417 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284769 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | ||
|date=02. | |date=02.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1111/rda.13091 | ||
}} | }} | ||
== | ==HLA-B== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | ||
|date= | |date=10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. | ||
|date= | |date=2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243 | ||
}} | }} | ||
== | ==IRF4== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation. | ||
|date= | |date=08.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice. | ||
|date= | |date=11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28905935 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672072 | |||
}} | }} | ||
== | ==PLD2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. | ||
|date= | |date=08.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Role of phospholipase D in the lifespan of Caenorhabditis elegans. | ||
|date= | |date=06.04.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29622768 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938010 | ||
}} | }} | ||
== | ==IDE== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity. | ||
|date= | |date=2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32538851 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.3233/JAD-200308 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Hyperinsulinemia is associated with increasing insulin secretion but not with decreasing insulin clearance in an age-related metabolic dysfunction mice model. | ||
|date= | |date=06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30370604 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1002/jcp.27667 | ||
}} | }} | ||
== | ==NPR1== | ||
* {{medline-title | * {{medline-title | ||
|title=[ | |title=The [[NPR1]]-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana. | ||
|date= | |date=03.12.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33270345 | ||
|full-text-url=https://sci-hub.do/10.1111/jipb.13044 | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis. | ||
|date= | |date=07.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32540002 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.plantsci.2020.110472 | ||
}} | }} | ||
== | ==CYP2D6== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. | ||
|date= | |date=05.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1002/bdd.2181 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug]. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30175758 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1248/yakushi.18-00114 | ||
}} | }} | ||
== | ==PAPPA== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | ||
|date= | |date=02.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1111/rda.13091 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. | ||
|date= | |date=12.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1111/jbg.12299 | ||
}} | }} | ||
== | ==ZC3H12A== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation. | ||
|date= | |date=12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31786670 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s00109-019-01853-2 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Prediction and characterization of human ageing-related proteins by using machine learning. | ||
|date= | |date=06.03.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29511309 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840292 | ||
}} | }} | ||
== | ==NMNAT2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[NMNAT2]]-mediated NAD generation is essential for quality control of aged oocytes. | ||
|date= | |date=06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909324 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy. | ||
|date= | |date=03.10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978465 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640801 | ||
}} | }} | ||
== | ==BMF== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=lncRNA-ES3/miR-34c-5p/[[BMF]] axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs. | ||
|date= | |date=17.01.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654331 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366973 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Aging, hematopoiesis, and the myelodysplastic syndromes. | ||
|date= | |date=08.12.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29222239 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142578 | ||
}} | }} | ||
== | ==ACAT1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. | ||
|date= | |date=06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. | ||
|date= | |date=15.12.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823 | ||
}} | }} | ||
== | ==CYLD== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Premature aging and cancer development in transgenic mice lacking functional [[CYLD]]. | ||
|date= | |date=10.01.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30631004 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339805 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis. | ||
|date= | |date=22.01.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554661 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.12.025 | ||
}} | }} | ||
== | ==POT1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=MiR-185 targets [[POT1]] to induce telomere dysfunction and cellular senescence. | ||
|date= | |date=18.07.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32687062 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425516 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Seryl tRNA synthetase cooperates with [[POT1]] to regulate telomere length and cellular senescence. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31815007 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882858 | ||
}} | }} | ||
== | ==CPQ== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A Spanish Adaptation of the Computer and Mobile Device Proficiency Questionnaires ([[CPQ]] and MDPQ) for Older Adults. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31214066 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554441 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Protective Effect of Semisynthetic and Natural Flavonoid on Aged Rat Microglia-enriched Cultures. | ||
|date= | |date=11.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31230229 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s12640-019-00071-5 | ||
}} | }} | ||
== | ==NRK== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/[[ULK1]] signaling activation]. | ||
|date= | |date=03.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989992 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20181205.001 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-[[ULK1]] signaling-mediated autophagy. | ||
|date= | |date=24.12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585174 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326678 | ||
}} | }} | ||
== | ==CCL20== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. | ||
|date= | |date=06.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272174 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.antiviral.2020.104784 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly. | ||
|date= | |date=02.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29193757 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1002/mnfr.201700307 | ||
}} | }} | ||
== | ==YAP1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. | ||
|date= | |date=25.06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis. | ||
|date= | |date=03.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607 | ||
}} | }} | ||
== | ==CYP1A2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of [[CYP1A2]]-Mediated Pharmacokinetics in Young and Elderly Chinese Adults. | ||
|date= | |date=07.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767128 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s40262-019-00737-5 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. | ||
|date= | |date=12.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442 | ||
}} | }} | ||
== | ==ARID1A== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Oncogenic mutations in histologically normal endometrium: the new normal? | ||
|date= | |date=10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1002/path.5314 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[ARID1A]] suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[[[CDKN2A]]]] regulatory axis. | ||
|date=18. | |date=18.11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942143 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.099 | ||
}} | }} | ||
== | ==CPD== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease. | ||
|date= | |date=05.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470706 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s00391-018-1377-9 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=What Do Clinical Supervisors Require to Teach Residents in Family Medicine How to Care for Seniors? | ||
|date= | |date=03.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29310735 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1017/S0714980817000460 | ||
}} | }} | ||
== | ==CYP27B1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance. | ||
|date=08. | |date=01.08.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955863 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693043 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism. | ||
|date= | |date=22.02.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470404 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823 | ||
}} | }} | ||
== | ==FHL2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Genetic associations with age of menopause in familial longevity. | ||
|date= | |date=10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=DNA methylation of the [[ELOVL2]], [[FHL2]], [[KLF14]], C1orf132/MIR29B2C, and [[TRIM59]] genes for age prediction from blood, saliva, and buccal swab samples. | ||
|date=01 | |date=01.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30300865 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010 | ||
}} | }} | ||
== | ==LRP5== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[LRP5]] in age-related changes in vascular and alveolar morphogenesis in the lung. | ||
|date= | |date=05.01.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30612120 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339783 | ||
}} | |||
* {{medline-title | |||
|title=Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand. | |||
|date=07.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30404864 | |||
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aau7137 | |||
}} | |||
==CFD== | |||
* {{medline-title | |||
|title=Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026383 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850482 | |||
}} | |||
* {{medline-title | |||
|title=New horizons in the compression of functional decline. | |||
|date=01.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165372 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201827 | |||
}} | |||
==CHI3L1== | |||
* {{medline-title | |||
|title=Postsynaptic damage and microglial activation in AD patients could be linked CXCR4/CXCL12 expression levels. | |||
|date=15.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32949560 | |||
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2020.147127 | |||
}} | |||
* {{medline-title | |||
|title=Sex difference in [[CHI3L1]] expression levels in human brain aging and in Alzheimer's disease. | |||
|date=01.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247206 | |||
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2019.146305 | |||
}} | |||
==FOXA1== | |||
* {{medline-title | |||
|title=Analyses of an epigenetic switch involved in the activation of pioneer factor [[FOXA1]] leading to the prognostic value of estrogen receptor and [[FOXA1]] co-expression in breast cancer. | |||
|date=28.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562808 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782010 | |||
}} | |||
* {{medline-title | |||
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. | |||
|date=05.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244 | |||
}} | |||
==CCL17== | |||
* {{medline-title | |||
|title=Aging and chronic high-fat feeding negatively affects kidney size, function, and gene expression in CTRP1-deficient mice. | |||
|date=21.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33085906 | |||
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00139.2020 | |||
}} | |||
* {{medline-title | |||
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. | |||
|date=21.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237 | |||
}} | |||
==SSB== | |||
* {{medline-title | |||
|title=Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study. | |||
|date=03.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816850 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950484 | |||
}} | |||
* {{medline-title | |||
|title=WHIRLY1 Occupancy Affects Histone Lysine Modification and [i]WRKY53[/i] Transcription in [i]Arabidopsis[/i] Developmental Manner. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30405658 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202938 | |||
}} | |||
==HGD== | |||
* {{medline-title | |||
|title=High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31846489 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917275 | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of [i]C. elegans[/i]. | ||
|date= | |date=05.10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299269 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224263 | ||
}} | }} | ||
== | ==SMAD2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation. | ||
|date= | |date=02.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31674011 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071816 | ||
}} | |||
* {{medline-title | |||
|title=Restoring extracellular matrix synthesis in senescent stem cells. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287964 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766659 | |||
}} | }} | ||
==LRP4== | |||
* {{medline-title | |||
|title=Multiple MuSK signaling pathways and the aging neuromuscular junction. | |||
|date=13.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32353380 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2020.135014 | |||
}} | |||
* {{medline-title | |||
|title=Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing [[LRP4]]. | |||
|date=10.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171091 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181315 | |||
}} | |||
==DDX58== | |||
* {{medline-title | |||
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood. | |||
|date=14.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791 | |||
}} | |||
* {{medline-title | |||
|title=Age-associated mRNA expression changes in bovine endometrial cells in vitro. | |||
|date=14.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28806906 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556672 | |||
}} | |||
==HAL== | |||
* {{medline-title | |||
|title=Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population. | |||
|date=06-09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31066639 | |||
|full-text-url=https://sci-hub.do/10.1080/15360288.2018.1513434 | |||
}} | |||
* {{medline-title | |||
|title=Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31049689 | |||
|full-text-url=https://sci-hub.do/10.1007/s00540-019-02646-0 | |||
}} | |||
==FAAH== | |||
* {{medline-title | |||
|title=Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32095523 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015690 | |||
}} | |||
* {{medline-title | |||
|title=Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911178 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548519 | |||
}} | |||
==FABP4== | |||
* {{medline-title | |||
|title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239 | |||
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797 | |||
}} | |||
* {{medline-title | |||
|title=Endothelial [[APLNR]] regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects. | |||
|date=13.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904225 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703224 | |||
}} | |||
==TREX1== | |||
* {{medline-title | |||
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287 | |||
}} | |||
* {{medline-title | |||
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 | |||
}} | |||
==MAP1LC3B== | |||
* {{medline-title | |||
|title=The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells. | |||
|date=01.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269563 | |||
|full-text-url=https://sci-hub.do/10.1556/2060.105.2018.3.20 | |||
}} | |||
* {{medline-title | |||
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528 | |||
}} | |||
==PYY== | |||
* {{medline-title | |||
|title=Peptide YY ([[PYY]]) Is Expressed in Human Skeletal Muscle Tissue and Expanding Human Muscle Progenitor Cells. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890955 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412030 | |||
}} | |||
* {{medline-title | |||
|title=Peptide YY induces characteristic meal patterns of aged mice. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28916138 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yhbeh.2017.09.003 | |||
}} | |||
==MAPK14== | |||
* {{medline-title | |||
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720 | |||
}} | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 | |||
}} | |||
==NCL== | |||
* {{medline-title | |||
|title=Factors Affecting Microvascular Responses in the Bulbar Conjunctiva in Habitual Contact Lens Wearers. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30098199 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088803 | |||
}} | |||
* {{medline-title | |||
|title=Small nucleoli are a cellular hallmark of longevity. | |||
|date=30.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28853436 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582349 | |||
}} | |||
==ACACA== | |||
* {{medline-title | |||
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009 | |||
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6 | |||
}} | |||
* {{medline-title | |||
|title=GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29694926 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bone.2018.04.014 | |||
}} | |||
==ATG3== | |||
* {{medline-title | |||
|title=Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells. | |||
|date=01.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32244623 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235898 | |||
}} | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
==AREG== | |||
* {{medline-title | |||
|title=Targeting amphiregulin ([[AREG]]) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31493351 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826133 | |||
}} | |||
* {{medline-title | |||
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663 | |||
}} | |||
==PTPN11== | |||
* {{medline-title | |||
|title=Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array. | |||
|date=01.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32888012 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568434 | |||
}} | |||
* {{medline-title | |||
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636 | |||
}} | |||
==NOP10== | |||
* {{medline-title | |||
|title=Pseudouridylation defect due to [i]DKC1[/i] and [i][[NOP10]][/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. | |||
|date=30.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554502 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334496 | |||
}} | |||
* {{medline-title | |||
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655 | |||
}} | |||
==MTM1== | |||
* {{medline-title | |||
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice. | |||
|date=20.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500 | |||
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866 | |||
}} | |||
* {{medline-title | |||
|title=Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy. | |||
|date=19.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451843 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243013 | |||
}} | |||
==IDS== | |||
* {{medline-title | |||
|title=Effect of immediate dentine sealing on the aging and fracture strength of lithium disilicate inlays and overlays. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32957211 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2020.103906 | |||
}} | |||
* {{medline-title | |||
|title=Increased double limb support times during walking in right limb dominant healthy older adults with low bone density. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730490 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gaitpost.2018.04.036 | |||
}} | |||
==SV2A== | |||
* {{medline-title | |||
|title=Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging. | |||
|date=01.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30014145 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233853 | |||
}} | |||
* {{medline-title | |||
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247 | |||
}} | |||
==NMNAT1== | |||
* {{medline-title | |||
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513 | |||
}} | |||
* {{medline-title | |||
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157 | |||
|full-text-url=https://sci-hub.do/10.1111/jbg.12299 | |||
}} | |||
==VCAM1== | |||
* {{medline-title | |||
|title=Sunitinib facilitates metastatic breast cancer spreading by inducing endothelial cell senescence. | |||
|date=29.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32993785 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526390 | |||
}} | |||
* {{medline-title | |||
|title=Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell [[VCAM1]]. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31086348 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642642 | |||
}} | |||
==NOS2== | |||
* {{medline-title | |||
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3 | |||
}} | |||
* {{medline-title | |||
|title=Secreted α-Klotho maintains cartilage tissue homeostasis by repressing [i][[NOS2]][/i] and [i]ZIP8-MMP13[/i] catabolic axis. | |||
|date=19.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29920476 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046234 | |||
}} | |||
==SCAP== | |||
* {{medline-title | |||
|title=Dementia outcomes after addition of proxy-based assessments for deceased or proxy-dependent participants. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31034676 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742525 | |||
}} | |||
* {{medline-title | |||
|title=Increased hepatic INSIG-[[SCAP]]-SREBP expression is associated with cholesterol metabolism disorder in assisted reproductive technology-conceived aged mice. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30562550 | |||
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2018.12.003 | |||
}} | |||
==AGER== | |||
* {{medline-title | |||
|title=Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model. | |||
|date=01.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31575929 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773724 | |||
}} | |||
* {{medline-title | |||
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551 | |||
}} | |||
==PDC== | |||
* {{medline-title | |||
|title=The mitochondrial translocase of the inner membrane PaTim54 is involved in defense response and longevity in Podospora anserina. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31351193 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fgb.2019.103257 | |||
}} | |||
* {{medline-title | |||
|title=Neuron-specific knockdown of Drosophila [[PDHB]] induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting. | |||
|date=15.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501567 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.02.035 | |||
}} | |||
==SLC25A24== | |||
* {{medline-title | |||
|title=De Novo Mutations in [[SLC25A24]] Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise. | |||
|date=02.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29100094 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673633 | |||
}} | |||
* {{medline-title | |||
|title=De Novo Mutations in [[SLC25A24]] Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction. | |||
|date=02.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29100093 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673623 | |||
}} | |||
==DICER1== | |||
* {{medline-title | |||
|title=[[DICER1]]: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087677 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066587 | |||
}} | |||
* {{medline-title | |||
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072 | |||
}} | |||
==LDHA== | |||
* {{medline-title | |||
|title=Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16 inactivation. | |||
|date=26.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482580 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828408 | |||
}} | |||
* {{medline-title | |||
|title=Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476819 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.004 | |||
}} | |||
==SNCB== | |||
* {{medline-title | |||
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016 | |||
}} | |||
* {{medline-title | |||
|title=Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808713 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047277 | |||
}} | |||
==AQP3== | |||
* {{medline-title | |||
|title=Transbuccal platform for delivery of lipogenic actives to facial skin: Because fat matters. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592290 | |||
|full-text-url=https://sci-hub.do/10.1002/term.3087 | |||
}} | |||
* {{medline-title | |||
|title=[Age-related changes of water transport by corneal endothelial cells in rats.] | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322730 | |||
}} | |||
==HRAS== | |||
* {{medline-title | |||
|title=How do combinations of unhealthy behaviors relate to attitudinal factors and subjective health among the adult population in the Netherlands? | |||
|date=03.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32245376 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126128 | |||
}} | |||
* {{medline-title | |||
|title=Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype. | |||
|date=07.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31940439 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032038 | |||
}} | |||
==SUV39H1== | |||
* {{medline-title | |||
|title=Increase in hippocampal histone H3K9me3 is negatively correlated with memory in old male mice. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31760560 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09850-1 | |||
}} | |||
* {{medline-title | |||
|title=Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation | |||
|date=27.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952292 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660 | |||
}} | |||
==E2F2== | |||
* {{medline-title | |||
|title=MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896785 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052401 | |||
}} | |||
* {{medline-title | |||
|title=In situ regeneration of retinal pigment epithelium by gene transfer of [[E2F2]]: a potential strategy for treatment of macular degenerations. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29188796 | |||
|full-text-url=https://sci-hub.do/10.1038/gt.2017.89 | |||
}} | |||
==VCAN== | |||
* {{medline-title | |||
|title=Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis. | |||
|date=07.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31051334 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495079 | |||
}} | |||
* {{medline-title | |||
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223 | |||
}} | |||
==EDARADD== | |||
* {{medline-title | |||
|title=Age prediction in living: Forensic epigenetic age estimation based on blood samples. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721866 | |||
|full-text-url=https://sci-hub.do/10.1016/j.legalmed.2020.101763 | |||
}} | |||
* {{medline-title | |||
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723 | |||
}} | |||
==TAT== | |||
* {{medline-title | |||
|title=Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31024341 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467974 | |||
}} | |||
* {{medline-title | |||
|title=Effects of HIV-1 gp120 and [[TAT]]-derived microvesicles on endothelial cell function. | |||
|date=01.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789287 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589811 | |||
}} | |||
==TCF7L2== | |||
* {{medline-title | |||
|title=A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32015540 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065955 | |||
}} | |||
* {{medline-title | |||
|title=Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle. | |||
|date=01.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30824849 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397284 | |||
}} | |||
==GRIK2== | |||
* {{medline-title | |||
|title=Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2. | |||
|date=11-12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099472 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675648 | |||
}} | |||
* {{medline-title | |||
|title=Isoforms of Ionotropic Glutamate Receptor [[GRIK2]] Induce Senescence of Carcinoma Cells. | |||
|date=01-02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30587499 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348395 | |||
}} | |||
==TTN== | |||
* {{medline-title | |||
|title=LncRNA [[TTN]]-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis. | |||
|date=10.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31600142 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814585 | |||
}} | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==PIEZO1== | |||
* {{medline-title | |||
|title=Niche stiffness underlies the ageing of central nervous system progenitor cells. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31413369 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025879 | |||
}} | |||
* {{medline-title | |||
|title=On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, [[PIEZO1]], and Gardos Channels. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29311949 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732905 | |||
}} | |||
==HAPLN1== | |||
* {{medline-title | |||
|title=Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279173 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328333 | |||
}} | |||
* {{medline-title | |||
|title=Age-Related Changes in [[HAPLN1]] Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279172 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328344 | |||
}} | |||
==DAPK1== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
* {{medline-title | |||
|title=Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of [[DAPK1]] in Aging. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30120735 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1312-5 | |||
}} | |||
==KIT== | |||
* {{medline-title | |||
|title=Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-[[KIT]]. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223330 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221484 | |||
}} | |||
* {{medline-title | |||
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.26231 | |||
}} | |||
==RIG== | |||
* {{medline-title | |||
|title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393 | |||
}} | |||
* {{medline-title | |||
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes. | |||
|date=12.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941 | |||
}} | |||
==CXCL5== | |||
* {{medline-title | |||
|title=Hassall's corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus. | |||
|date=05.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534943 | |||
|full-text-url=https://sci-hub.do/10.1093/intimm/dxy073 | |||
}} | |||
* {{medline-title | |||
|title=Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891542 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105902 | |||
}} | |||
==MEIS1== | |||
* {{medline-title | |||
|title=Down-regulation of [[MEIS1]] promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884246 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529342 | |||
}} | |||
* {{medline-title | |||
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015 | |||
}} | |||
==CCNG2== | |||
* {{medline-title | |||
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318 | |||
}} | |||
* {{medline-title | |||
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220 | |||
}} | |||
==BGN== | |||
* {{medline-title | |||
|title=Alterations of local functional connectivity in lifespan: A resting-state fMRI study. | |||
|date=07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32462815 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375100 | |||
}} | |||
* {{medline-title | |||
|title=Exploring variability in basal ganglia connectivity with functional MRI in healthy aging. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29442271 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302142 | |||
}} | |||
==TRPM8== | |||
* {{medline-title | |||
|title=Morphological and functional changes in [[TRPM8]]-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29664111 | |||
|full-text-url=https://sci-hub.do/10.1002/cne.24454 | |||
}} | |||
* {{medline-title | |||
|title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699 | |||
|full-text-url=https://sci-hub.do/10.1111/nmo.13185 | |||
}} | |||
==HLA-A== | |||
* {{medline-title | |||
|title=Reduced expression of the lncRNA NRON is a potential hallmark of the CMV-amplified CD8+ T cell accumulations commonly seen in older humans. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415066 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.004 | |||
}} | |||
* {{medline-title | |||
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243 | |||
}} | |||
==PER1== | |||
* {{medline-title | |||
|title=Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31773385 | |||
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05194-8 | |||
}} | |||
* {{medline-title | |||
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. | |||
|date=21.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686 | |||
}} | |||
==RUNX1== | |||
* {{medline-title | |||
|title=RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing [[RUNX1]] fusion oncoproteins. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29052866 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813226 | |||
}} | |||
* {{medline-title | |||
|title=Sequential acquisition of mutations in myelodysplastic syndromes. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821 | |||
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828 | |||
}} | |||
==CCL21== | |||
* {{medline-title | |||
|title=[[CCL21]]/[[CCR7]] axis regulating juvenile cartilage repair can enhance cartilage healing in adults. | |||
|date=26.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30914733 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435673 | |||
}} | |||
* {{medline-title | |||
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433 | |||
}} | |||
==PIK3CG== | |||
* {{medline-title | |||
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway. | |||
|date=10.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820 | |||
}} | |||
* {{medline-title | |||
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells. | |||
|date=18.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757 | |||
}} | |||
==TBK1== | |||
* {{medline-title | |||
|title=Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of [[TBK1]] to facilitate mitophagy. | |||
|date=01.01.2021 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33164878 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165997 | |||
}} | |||
* {{medline-title | |||
|title=[[TBK1]] Suppresses [[RIPK1]]-Driven Apoptosis and Inflammation during Development and in Aging. | |||
|date=06.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30146158 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128749 | |||
}} | |||
==AMT== | |||
* {{medline-title | |||
|title=A multi-method comparison of autobiographical memory impairments amongst younger and older adults. | |||
|date=12.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162531 | |||
|full-text-url=https://sci-hub.do/10.1080/13607863.2020.1729338 | |||
}} | |||
* {{medline-title | |||
|title=Autobiographical Memory From Different Life Stages in Individuals With Obstructive Sleep Apnea. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696518 | |||
|full-text-url=https://sci-hub.do/10.1017/S1355617718001091 | |||
}} | |||
==CDK1== | |||
* {{medline-title | |||
|title=MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31848878 | |||
|full-text-url=https://sci-hub.do/10.1007/s12015-019-09924-0 | |||
}} | |||
* {{medline-title | |||
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578 | |||
}} | |||
==FN1== | |||
* {{medline-title | |||
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. | |||
|date=22.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318 | |||
}} | |||
* {{medline-title | |||
|title=Effects of Fibronectin 1 on Cell Proliferation, Senescence and Apoptosis of Human Glioma Cells Through the PI3K/AKT Signaling Pathway. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048971 | |||
|full-text-url=https://sci-hub.do/10.1159/000492096 | |||
}} | |||
==HCN1== | |||
* {{medline-title | |||
|title=Protein expression changes of [[HCN1]] and HCN2 in hippocampal subregions of gerbils during the normal aging process. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32128096 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038419 | |||
}} | |||
* {{medline-title | |||
|title=HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation. | |||
|date=15.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30124776 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376092 | |||
}} | |||
==TRPC6== | |||
* {{medline-title | |||
|title=Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32686475 | |||
|full-text-url=https://sci-hub.do/10.1177/1535370220943122 | |||
}} | |||
* {{medline-title | |||
|title=[[TRPC6]] in simulated microgravity of intervertebral disc cells. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29968164 | |||
|full-text-url=https://sci-hub.do/10.1007/s00586-018-5688-8 | |||
}} | |||
==ALKBH8== | |||
* {{medline-title | |||
|title=Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming . | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765888 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904832 | |||
}} | |||
* {{medline-title | |||
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756 | |||
}} | |||
==PF4== | |||
* {{medline-title | |||
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681 | |||
|full-text-url=https://sci-hub.do/10.1002/prca.201800024 | |||
}} | |||
* {{medline-title | |||
|title=Effects of collagen peptides intake on skin ageing and platelet release in chronologically aged mice revealed by cytokine array analysis. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28922541 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742730 | |||
}} | |||
==MAPK3== | |||
* {{medline-title | |||
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636 | |||
}} | |||
* {{medline-title | |||
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720 | |||
}} | |||
==GATA3== | |||
* {{medline-title | |||
|title=An imbalance in the T-helper phenotypes displayed by senescent [[CD4]] [[CD28]] T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111238 | |||
|full-text-url=https://sci-hub.do/10.1177/0961203318793715 | |||
}} | |||
* {{medline-title | |||
|title=Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30004288 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262508 | |||
}} | |||
==HLA-DPB1== | |||
* {{medline-title | |||
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488 | |||
}} | |||
* {{medline-title | |||
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | |||
}} | |||
==BAK1== | |||
* {{medline-title | |||
|title=Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon. | |||
|date=23.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32710818 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529960 | |||
}} | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
==BECN1== | |||
* {{medline-title | |||
|title=Calpain-dependent Beclin1 cleavage stimulates senescence-associated cell death in HT22 hippocampal cells under the oxidative stress conditions. | |||
|date=14.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30807795 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2019.02.036 | |||
}} | |||
* {{medline-title | |||
|title=Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-[[ULK1]] signaling pathway. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344647 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810242 | |||
}} | |||
==TIMP1== | |||
* {{medline-title | |||
|title=Design, cyclization, and optimization of [[MMP13]]-[[TIMP1]] interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352228 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.10.141 | |||
}} | |||
* {{medline-title | |||
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478 | |||
}} | |||
==APOA5== | |||
* {{medline-title | |||
|title=Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30700132 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399473 | |||
}} | |||
* {{medline-title | |||
|title=Longitudinal interaction between [[APOA5]] -1131T>C and overweight in the acceleration of age-related increase in arterial stiffness through the regulation of circulating triglycerides. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451986 | |||
|full-text-url=https://sci-hub.do/10.1038/s41440-018-0137-y | |||
}} | |||
==FOXF1== | |||
* {{medline-title | |||
|title=Functional CRISPR screen identifies AP1-associated enhancer regulating [[FOXF1]] to modulate oncogene-induced senescence. | |||
|date=17.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119690 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097335 | |||
}} | |||
* {{medline-title | |||
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. | |||
|date=26.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307 | |||
}} | |||
==GK== | |||
* {{medline-title | |||
|title=Progression of diabetic kidney disease in T2DN rats. | |||
|date=01.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566426 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960784 | |||
}} | |||
* {{medline-title | |||
|title=Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30609251 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413652 | |||
}} | |||
==TMPRSS2== | |||
* {{medline-title | |||
|title=Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants. | |||
|date=09.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32905655 | |||
|full-text-url=https://sci-hub.do/10.1002/jbt.22626 | |||
}} | |||
* {{medline-title | |||
|title=Expression of the SARS-CoV-2 Entry Proteins, ACE2 and [[TMPRSS2]], in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. | |||
|date=03.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32379417 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241737 | |||
}} | |||
==SOST== | |||
* {{medline-title | |||
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448 | |||
}} | |||
* {{medline-title | |||
|title=Bone adaptation in response to treadmill exercise in young and adult mice. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29379848 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787623 | |||
}} | |||
==S1PR1== | |||
* {{medline-title | |||
|title=Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair. | |||
|date=22.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544390 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607448 | |||
}} | |||
* {{medline-title | |||
|title=Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota. | |||
|date=04.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302034 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754350 | |||
}} | |||
==PRC1== | |||
* {{medline-title | |||
|title=Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein [[BMI1]] in breast cancer cells. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528145 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986597 | |||
}} | |||
* {{medline-title | |||
|title=Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177687 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9737-1 | |||
}} | |||
==MTMR14== | |||
* {{medline-title | |||
|title=EDTP/[[MTMR14]]: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates. | |||
|date=13.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31029679 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2019.04.053 | |||
}} | |||
* {{medline-title | |||
|title=Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster. | |||
|date=16.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30528881 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.12.009 | |||
}} | |||
==ZSCAN10== | |||
* {{medline-title | |||
|title=RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells. | |||
|date=10.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020613 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639470 | |||
}} | |||
* {{medline-title | |||
|title=[[ZSCAN10]] expression corrects the genomic instability of iPSCs from aged donors. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846095 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843481 | |||
}} | |||
==CXCL11== | |||
* {{medline-title | |||
|title=Endothelial cells under therapy-induced senescence secrete [[CXCL11]], which increases aggressiveness of breast cancer cells. | |||
|date=10.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659248 | |||
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2020.06.019 | |||
}} | |||
* {{medline-title | |||
|title=Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity. | |||
|date=13.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30867067 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417215 | |||
}} | |||
==ADAM17== | |||
* {{medline-title | |||
|title=ACE2/[[ADAM17]]/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575774 | |||
}} | |||
* {{medline-title | |||
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | |||
|date=25.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | |||
}} | |||
==HMOX1== | |||
* {{medline-title | |||
|title=Well-aging: A new strategy for skin homeostasis under multi-stressed conditions. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31232507 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003805 | |||
}} | |||
* {{medline-title | |||
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016 | |||
}} | |||
==DLX5== | |||
* {{medline-title | |||
|title=Inhibition of microRNA-27b-3p relieves osteoarthritis pain via regulation of KDM4B-dependent [[DLX5]]. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856377 | |||
|full-text-url=https://sci-hub.do/10.1002/biof.1670 | |||
}} | |||
* {{medline-title | |||
|title=Detection and evaluation of DNA methylation markers found at [[SCGN]] and [[KLF14]] loci to estimate human age. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854399 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011 | |||
}} | |||
==MARCO== | |||
* {{medline-title | |||
|title=Age-dependent effect between [[MARCO]] and [[TLR4]] on PMMA particle phagocytosis by macrophages. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225947 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653467 | |||
}} | |||
* {{medline-title | |||
|title=Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria. | |||
|date=01.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28947541 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679440 | |||
}} | |||
==CDKN2B== | |||
* {{medline-title | |||
|title=Molecular Genetics and Functional Analysis Implicate [i][[CDKN2B]]AS1-[[CDKN2B]][/i] Involvement in POAG Pathogenesis. | |||
|date=21.08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32825664 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564117 | |||
}} | |||
* {{medline-title | |||
|title=Interference of the long noncoding RNA [[CDKN2B]]-AS1 upregulates miR-181a-5p/TGFβI axis to restrain the metastasis and promote apoptosis and senescence of cervical cancer cells. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884187 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488111 | |||
}} | |||
==LIF== | |||
* {{medline-title | |||
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity. | |||
|date=25.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174 | |||
}} | |||
* {{medline-title | |||
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. | |||
|date=15.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304 | |||
}} | |||
==CCN3== | |||
* {{medline-title | |||
|title=[[CCN3]] Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304321 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701218 | |||
}} | |||
* {{medline-title | |||
|title=[[CCN3]] (NOV) Drives Degradative Changes in Aging Articular Cartilage. | |||
|date=13.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066270 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593953 | |||
}} | |||
==FOXP3== | |||
* {{medline-title | |||
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663 | |||
}} | |||
* {{medline-title | |||
|title=Enhanced expression of PD-1 and other activation markers by CD4+ T cells of young but not old patients with metastatic melanoma. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546435 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951899 | |||
}} | |||
==PSEN2== | |||
* {{medline-title | |||
|title=Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human [[PSEN2]]. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31978074 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980398 | |||
}} | |||
* {{medline-title | |||
|title=Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31862541 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462087 | |||
}} | |||
==C9orf72== | |||
* {{medline-title | |||
|title=Carriership of two copies of [[C9orf72]] hexanucleotide repeat intermediate-length alleles is a risk factor for ALS in the Finnish population. | |||
|date=09.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168078 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654028 | |||
}} | |||
* {{medline-title | |||
|title=[[C9]]orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons. | |||
|date=29.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037833 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705968 | |||
}} | |||
==DSP== | |||
* {{medline-title | |||
|title=Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247288 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754798 | |||
}} | |||
* {{medline-title | |||
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171 | |||
}} | |||
==F7== | |||
* {{medline-title | |||
|title=The Pattern of Mu Rhythm Modulation During Emotional Destination Memory: Comparison Between Mild Cognitive Impairment Patients and Healthy Controls. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524160 | |||
|full-text-url=https://sci-hub.do/10.3233/JAD-190311 | |||
}} | |||
* {{medline-title | |||
|title=High levels of incidental physical activity are positively associated with cognition and EEG activity in aging. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29370215 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784952 | |||
}} | |||
==ATG12== | |||
* {{medline-title | |||
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 | |||
}} | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
==FANCD2== | |||
* {{medline-title | |||
|title=TFG-maintaining stability of overlooked [[FANCD2]] confers early DNA-damage response. | |||
|date=24.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099537 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655164 | |||
}} | |||
* {{medline-title | |||
|title=[[FANCD2]] and DNA Damage. | |||
|date=19.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825622 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578191 | |||
}} | |||
==CAST== | |||
* {{medline-title | |||
|title=Cytomatrix proteins [[CAST]] and ELKS regulate retinal photoreceptor development and maintenance. | |||
|date=05.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30190286 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219712 | |||
}} | |||
* {{medline-title | |||
|title=Short Telomeres Induce p53 and Autophagy and Modulate Age-Associated Changes in Cardiac Progenitor Cell Fate. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29441645 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992026 | |||
}} | |||
==DRD3== | |||
* {{medline-title | |||
|title=Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30439596 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.10.012 | |||
}} | |||
* {{medline-title | |||
|title=Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29637543 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105503 | |||
}} | |||
==ID3== | |||
* {{medline-title | |||
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640 | |||
}} | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
==CHM== | |||
* {{medline-title | |||
|title=[Molecular regulative mechanisms of aging and interventional effects of Chinese herbal medicine]. | |||
|date=08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171222 | |||
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20170731.001 | |||
}} | |||
* {{medline-title | |||
|title=[Molecular mechanisms of autophagy in regulating renal aging and interventional effects of Chinese herbal medicine]. | |||
|date=11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28929674 | |||
|full-text-url=https://sci-hub.do/10.4268/cjcmm20162105 | |||
}} | |||
==GPR39== | |||
* {{medline-title | |||
|title=Zinc-mediated Neurotransmission in Alzheimer's Disease: A Potential Role of the [[GPR39]] in Dementia. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31272355 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327932 | |||
}} | |||
* {{medline-title | |||
|title=[[GPR39]] agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237151 | |||
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1626405 | |||
}} | |||
==B2M== | |||
* {{medline-title | |||
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468 | |||
}} | |||
* {{medline-title | |||
|title=Association between serum β2-microglobulin levels and frailty in an elderly Chinese population: results from RuLAS. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081654 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652941 | |||
}} | |||
==HBP1== | |||
* {{medline-title | |||
|title=Suppression of p38/[[HBP1]] pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence. | |||
|date=03-04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32549582 | |||
|full-text-url=https://sci-hub.do/10.23812/20-63-A-6 | |||
}} | |||
* {{medline-title | |||
|title=Transcription factor [[HBP1]]: A regulator of senescence and apoptosis of preadipocytes. | |||
|date=17.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331641 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.07.048 | |||
}} | |||
==DEGS1== | |||
* {{medline-title | |||
|title=[Frailty: Prevalence in the Resident Population of Germany 70 - 79 Years of Age - a Population-Based Approach]. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29156480 | |||
|full-text-url=https://sci-hub.do/10.1055/s-0043-105841 | |||
}} | |||
* {{medline-title | |||
|title=Physical exercise and cognitive function across the life span: Results of a nationwide population-based study. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28919495 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jsams.2017.08.022 | |||
}} | |||
==ACOX1== | |||
* {{medline-title | |||
|title=Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677513 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2019.01.005 | |||
}} | |||
* {{medline-title | |||
|title=Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765501 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889864 | |||
}} | |||
==TXNRD2== | |||
* {{medline-title | |||
|title=Wogonin induces cellular senescence in breast cancer via suppressing [[TXNRD2]] expression. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32671444 | |||
|full-text-url=https://sci-hub.do/10.1007/s00204-020-02842-y | |||
}} | |||
* {{medline-title | |||
|title=Loss of [[IDH2]] Accelerates Age-related Hearing Loss in Male Mice. | |||
|date=22.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567975 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864918 | |||
}} | |||
==SAA1== | |||
* {{medline-title | |||
|title=Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617422 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884545 | |||
}} | |||
* {{medline-title | |||
|title=Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846716 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573208 | |||
}} | |||
==STIM1== | |||
* {{medline-title | |||
|title=Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31833196 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996945 | |||
}} | |||
* {{medline-title | |||
|title=Ca entry via [[TRPC1]] is essential for cellular differentiation and modulates secretion via the SNARE complex. | |||
|date=01.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182642 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397 | |||
}} | |||
==LAMP2== | |||
* {{medline-title | |||
|title=A pH probe inhibits senescence in mesenchymal stem cells. | |||
|date=07.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523 | |||
}} | |||
* {{medline-title | |||
|title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022 | |||
}} | |||
==CPE== | |||
* {{medline-title | |||
|title=Cross-Sectional and Cumulative Longitudinal Central Nervous System Penetration Effectiveness Scores Are Not Associated With Neurocognitive Impairment in a Well Treated Aging Human Immunodeficiency Virus-Positive Population in Switzerland. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304188 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612860 | |||
}} | |||
* {{medline-title | |||
|title=COCOA (Theobroma cacao) Polyphenol-Rich Extract Increases the Chronological Lifespan of Saccharomyces cerevisiae. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29240368 | |||
}} | |||
==STAT5A== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
* {{medline-title | |||
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes. | |||
|date=28.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560 | |||
}} | |||
==NTS== | |||
* {{medline-title | |||
|title=Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140326 | |||
|full-text-url=https://sci-hub.do/10.1080/07420528.2019.1613424 | |||
}} | |||
* {{medline-title | |||
|title=Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518407 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019141 | |||
}} | |||
==PGP== | |||
* {{medline-title | |||
|title=Age-associated changes of the intrinsic nervous system in relation with interstitial cells in the pre-weaning goat rumen. | |||
|date=14.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31305258 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660047 | |||
}} | |||
* {{medline-title | |||
|title=Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182640 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705109 | |||
}} | |||
==GDF3== | |||
* {{medline-title | |||
|title=In vivo [[GDF3]] administration abrogates aging related muscle regeneration delay following acute sterile injury. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003692 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156497 | |||
}} | |||
* {{medline-title | |||
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. | |||
|date=05.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149 | |||
}} | |||
==TNNT3== | |||
* {{medline-title | |||
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. | |||
|date=06.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057 | |||
}} | |||
* {{medline-title | |||
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs. | |||
|date=15.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179 | |||
}} | |||
==GPT== | |||
* {{medline-title | |||
|title=Brain Structural-Behavioral Correlates Underlying Grooved Pegboard Test Performance Across Lifespan. | |||
|date=07.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32631206 | |||
|full-text-url=https://sci-hub.do/10.1080/00222895.2020.1787320 | |||
}} | |||
* {{medline-title | |||
|title=Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31275139 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592113 | |||
}} | |||
==ANGPTL2== | |||
* {{medline-title | |||
|title=Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study. | |||
|date=01.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31840173 | |||
|full-text-url=https://sci-hub.do/10.1093/ndt/gfz236 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice. | |||
|date=02.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29191837 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798292 | |||
}} | |||
==IL1A== | |||
* {{medline-title | |||
|title=IL1B triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via CCL2. | |||
|date=25.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099841 | |||
|full-text-url=https://sci-hub.do/10.1111/aji.13365 | |||
}} | |||
* {{medline-title | |||
|title=Age-associated mRNA expression changes in bovine endometrial cells in vitro. | |||
|date=14.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28806906 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556672 | |||
}} | |||
==PUM2== | |||
* {{medline-title | |||
|title=PUMILIO hyperactivity drives premature aging of [i]Norad[/i]-deficient mice. | |||
|date=08.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735131 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407921 | |||
}} | |||
* {{medline-title | |||
|title=The RNA-Binding Protein [[PUM2]] Impairs Mitochondrial Dynamics and Mitophagy During Aging. | |||
|date=21.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30642763 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396316 | |||
}} | |||
==BTK== | |||
* {{medline-title | |||
|title=Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31736210 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974713 | |||
}} | |||
* {{medline-title | |||
|title=[[BTK]] suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling. | |||
|date=22.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28915637 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593608 | |||
}} | |||
==MALT1== | |||
* {{medline-title | |||
|title=MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. | |||
|date=29.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32350248 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190641 | |||
}} | |||
* {{medline-title | |||
|title=[[MALT1]]-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31632405 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779721 | |||
}} | |||
==DAO== | |||
* {{medline-title | |||
|title=Age- and gender-dependent D-amino acid oxidase activity in mouse brain and peripheral tissues: implication for aging and neurodegeneration. | |||
|date=01.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30938755 | |||
|full-text-url=https://sci-hub.do/10.1093/jb/mvz025 | |||
}} | |||
* {{medline-title | |||
|title=Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging. | |||
|date=01.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29093468 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665939 | |||
}} | |||
==FSTL3== | |||
* {{medline-title | |||
|title=Activin type II receptor signaling in cardiac aging and heart failure. | |||
|date=06.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842316 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124007 | |||
}} | |||
* {{medline-title | |||
|title=Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise. | |||
|date=01.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30085147 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179167 | |||
}} | |||
==BMP15== | |||
* {{medline-title | |||
|title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012 | |||
|full-text-url=https://sci-hub.do/10.1002/mrd.23079 | |||
}} | |||
* {{medline-title | |||
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. | |||
|date=18.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463 | |||
}} | |||
==GIT2== | |||
* {{medline-title | |||
|title=Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic [[GIT2]] in aging trajectories. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31574270 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111150 | |||
}} | |||
* {{medline-title | |||
|title=[[GIT2]]-A keystone in ageing and age-related disease. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002 | |||
}} | |||
==PTS== | |||
* {{medline-title | |||
|title=Posttraumatic stress symptom persistence across 24 years: association with brain structures. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30830577 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722032 | |||
}} | |||
* {{medline-title | |||
|title=Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis. | |||
|date=18.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021511 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052528 | |||
}} | |||
==FUNDC1== | |||
* {{medline-title | |||
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence. | |||
|date=15.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833 | |||
}} | |||
* {{medline-title | |||
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. | |||
|date=01.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068 | |||
}} | |||
==GNG3== | |||
* {{medline-title | |||
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720 | |||
}} | |||
* {{medline-title | |||
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205 | |||
}} | |||
==CRABP2== | |||
* {{medline-title | |||
|title=Preconception resveratrol intake against infertility: Friend or foe? | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32273814 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138940 | |||
}} | |||
* {{medline-title | |||
|title=Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females. | |||
|date=31.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089527 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663855 | |||
}} | |||
==GRSF1== | |||
* {{medline-title | |||
|title=[[GRSF1]] is an age-related regulator of senescence. | |||
|date=03.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944385 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447602 | |||
}} | |||
* {{medline-title | |||
|title=[[GRSF1]] suppresses cell senescence. | |||
|date=07.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30086537 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128438 | |||
}} | |||
==BIN1== | |||
* {{medline-title | |||
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice. | |||
|date=20.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500 | |||
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866 | |||
}} | |||
* {{medline-title | |||
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. | |||
|date=28.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389 | |||
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049 | |||
}} | |||
==IL7== | |||
* {{medline-title | |||
|title=[[SCAMP4]] enhances the senescent cell secretome. | |||
|date=01.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967290 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075036 | |||
}} | |||
* {{medline-title | |||
|title=Thymic Atrophy: Experimental Studies and Therapeutic Interventions. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28960415 | |||
|full-text-url=https://sci-hub.do/10.1111/sji.12618 | |||
}} | |||
==LOXL2== | |||
* {{medline-title | |||
|title=Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice. | |||
|date=27.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31569601 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801581 | |||
}} | |||
* {{medline-title | |||
|title=Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening. | |||
|date=01.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002285 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692735 | |||
}} | |||
==WIPI2== | |||
* {{medline-title | |||
|title=Neuronal autophagy declines substantially with age and is rescued by overexpression of [[WIPI2]]. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794336 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984449 | |||
}} | |||
* {{medline-title | |||
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875 | |||
}} | |||
==TBC1D5== | |||
* {{medline-title | |||
|title=[[TBC1D5]]-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry. | |||
|date=09.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32521275 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339955 | |||
}} | |||
* {{medline-title | |||
|title=Retromer and [[TBC1D5]] maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling. | |||
|date=02.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31431476 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719456 | |||
}} | |||
==PLK4== | |||
* {{medline-title | |||
|title=A novel lncRNA [[PLK4]] up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32243714 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205816 | |||
}} | |||
* {{medline-title | |||
|title=Differential expression of AURKA/[[PLK4]] in quiescence and senescence of osteosarcoma U2OS cells. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32200684 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217361 | |||
}} | |||
==LCT== | |||
* {{medline-title | |||
|title=Functional MRI of Letter Cancellation Task Performance in Older Adults. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31057377 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477506 | |||
}} | |||
* {{medline-title | |||
|title=Milk Intake at Midlife and Cognitive Decline over 20 Years. The Atherosclerosis Risk in Communities (ARIC) Study. | |||
|date=17.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039795 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691750 | |||
}} | |||
==XRCC1== | |||
* {{medline-title | |||
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats]. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111059 | |||
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180408.005 | |||
}} | |||
* {{medline-title | |||
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081 | |||
}} | |||
==GAS6== | |||
* {{medline-title | |||
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663 | |||
}} | |||
* {{medline-title | |||
|title=Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28957414 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619771 | |||
}} | |||
==SPR== | |||
* {{medline-title | |||
|title=Regulation of lifespan by neural excitation and REST. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31619788 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893853 | |||
}} | |||
* {{medline-title | |||
|title=How many geriatricians should, at minimum, be staffing health regions in Australia? | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171127 | |||
|full-text-url=https://sci-hub.do/10.1111/ajag.12467 | |||
}} | |||
==RTEL1== | |||
* {{medline-title | |||
|title=Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31444995 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826144 | |||
}} | |||
* {{medline-title | |||
|title=Genome-wide association study of telomere length among South Asians identifies a second [[RTEL1]] association signal. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29151059 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749304 | |||
}} | |||
==CBL== | |||
* {{medline-title | |||
|title=Effects of cerebrolysin on nerve growth factor system in the aging rat brain. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172008 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701766 | |||
}} | |||
* {{medline-title | |||
|title=Skeletal Muscle CAP Expression Increases after Dietary Restriction and Aerobic Training in Women with a History of Gestational Diabetes. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28989819 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628746 | |||
}} | |||
==CCR6== | |||
* {{medline-title | |||
|title=Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696983 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474 | |||
}} | |||
* {{medline-title | |||
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. | |||
|date=19.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985 | |||
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052 | |||
}} | |||
==LONP1== | |||
* {{medline-title | |||
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence. | |||
|date=15.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833 | |||
}} | |||
* {{medline-title | |||
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. | |||
|date=01.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068 | |||
}} | |||
==TRPM7== | |||
* {{medline-title | |||
|title=mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29842890 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.05.008 | |||
}} | |||
* {{medline-title | |||
|title=Role of kinase-coupled TRP channels in mineral homeostasis. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129644 | |||
|full-text-url=https://sci-hub.do/10.1016/j.pharmthera.2017.11.003 | |||
}} | |||
==PDCD4== | |||
* {{medline-title | |||
|title=Petal abscission in roses is associated with the activation of a truncated version of the animal [[PDCD4]] homologue, RbPCD1. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521226 | |||
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2019.110242 | |||
}} | |||
* {{medline-title | |||
|title=[[PDCD4]] Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30687637 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334536 | |||
}} | |||
==TLR7== | |||
* {{medline-title | |||
|title=Bovine Lactoferrin Enhances [[TLR7]]-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515164 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255898 | |||
}} | |||
* {{medline-title | |||
|title=B cell responses to apoptotic cells in MFG-E8-/- mice. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30286201 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171925 | |||
}} | |||
==PGD== | |||
* {{medline-title | |||
|title=Primary Care for the Elderly Bereaved: Recommendations for Medical Education. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29500657 | |||
|full-text-url=https://sci-hub.do/10.1007/s10880-018-9556-9 | |||
}} | |||
* {{medline-title | |||
|title=High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles. | |||
|date=01.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29303233 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844656 | |||
}} | |||
==PTX3== | |||
* {{medline-title | |||
|title=Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. | |||
|date=27.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012711 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070734 | |||
}} | |||
* {{medline-title | |||
|title=Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study. | |||
|date=13.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31808814 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357589 | |||
}} | |||
==TAS2R38== | |||
* {{medline-title | |||
|title=[[TAS2R38]] bitter taste receptor and attainment of exceptional longevity. | |||
|date=02.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792278 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889489 | |||
}} | |||
* {{medline-title | |||
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. | |||
|date=18.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100 | |||
}} | |||
==ETS1== | |||
* {{medline-title | |||
|title=The transcription factor [[ETS1]] promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1. | |||
|date=06.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31659122 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901313 | |||
}} | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 | |||
}} | |||
==SMAD4== | |||
* {{medline-title | |||
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125 | |||
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7 | |||
}} | |||
* {{medline-title | |||
|title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type p53. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985 | |||
}} | |||
==DDB1== | |||
* {{medline-title | |||
|title=DCAF1 regulates Treg senescence via the ROS axis during immunological aging. | |||
|date=02.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32730228 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598062 | |||
}} | |||
* {{medline-title | |||
|title=Deletion of [[DDB1]]- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. | |||
|date=15.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907856 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003934 | |||
}} | |||
==DKC1== | |||
* {{medline-title | |||
|title=Successful liver transplantation in short telomere syndromes without bone marrow failure due to [[DKC1]] mutation. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32166868 | |||
|full-text-url=https://sci-hub.do/10.1111/petr.13695 | |||
}} | |||
* {{medline-title | |||
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655 | |||
}} | |||
==DST== | |||
* {{medline-title | |||
|title=Ancestral germen/soma distinction in microbes: Expanding the disposable soma theory of aging to all unicellular lineages. | |||
|date=07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268207 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101064 | |||
}} | |||
* {{medline-title | |||
|title=Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386173 | |||
|full-text-url=https://sci-hub.do/10.1111/jgs.16089 | |||
}} | |||
==S100A4== | |||
* {{medline-title | |||
|title=Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice. | |||
|date=15.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678243 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894395 | |||
}} | |||
* {{medline-title | |||
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325 | |||
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217 | |||
}} | |||
==DDX41== | |||
* {{medline-title | |||
|title=Salidroside influences the cellular cross-talk of human fetal lung diploid fibroblasts: A proteomic approach. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29329019 | |||
|full-text-url=https://sci-hub.do/10.1016/j.etap.2018.01.001 | |||
}} | |||
* {{medline-title | |||
|title=Sequential acquisition of mutations in myelodysplastic syndromes. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821 | |||
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828 | |||
}} | |||
==MVD== | |||
* {{medline-title | |||
|title=Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297390 | |||
|full-text-url=https://sci-hub.do/10.1136/jim-2018-000804 | |||
}} | |||
* {{medline-title | |||
|title=Assessing Microvascular Function in Humans from a Chronic Disease Perspective. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904002 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698072 | |||
}} | |||
==GALT== | |||
* {{medline-title | |||
|title=Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30523311 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375790 | |||
}} | |||
* {{medline-title | |||
|title=Dietary Animal Plasma Proteins Improve the Intestinal Immune Response in Senescent Mice. | |||
|date=11.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29232896 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748796 | |||
}} | |||
==GATA2== | |||
* {{medline-title | |||
|title=[[GATA2]] hypomorphism induces chronic myelomonocytic leukemia in mice. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710465 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447832 | |||
}} | |||
* {{medline-title | |||
|title=Sequential acquisition of mutations in myelodysplastic syndromes. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821 | |||
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828 | |||
}} | |||
==ACTA1== | |||
* {{medline-title | |||
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. | |||
|date=15.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004 | |||
}} | |||
* {{medline-title | |||
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. | |||
|date=15.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823 | |||
}} | |||
==CYP3A4== | |||
* {{medline-title | |||
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942 | |||
|full-text-url=https://sci-hub.do/10.1002/bdd.2181 | |||
}} | |||
* {{medline-title | |||
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906 | |||
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442 | |||
}} | |||
==ACTB== | |||
* {{medline-title | |||
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261 | |||
}} | |||
* {{medline-title | |||
|title=WNT-activated bone grafts repair osteonecrotic lesions in aged animals. | |||
|date=27.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29079746 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660190 | |||
}} | |||
==AGT== | |||
* {{medline-title | |||
|title=SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441382 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469683 | |||
}} | |||
* {{medline-title | |||
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004 | |||
}} | |||
==ZEB2== | |||
* {{medline-title | |||
|title=miR-200b regulates cellular senescence and inflammatory responses by targeting [[ZEB2]] in pulmonary emphysema. | |||
|date=12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32070140 | |||
|full-text-url=https://sci-hub.do/10.1080/21691401.2020.1725029 | |||
}} | |||
* {{medline-title | |||
|title=MicroRNA-145 induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by [[ZEB2]]. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30479019 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.27521 | |||
}} | |||
==PDE4D== | |||
* {{medline-title | |||
|title=Phosphodiesterase [[PDE4D]] Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33192469 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655962 | |||
}} | |||
* {{medline-title | |||
|title=Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function. | |||
|date=02.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30409425 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.180 | |||
}} | |||
==RAD52== | |||
* {{medline-title | |||
|title=Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae. | |||
|date=01.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075257 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563841 | |||
}} | |||
* {{medline-title | |||
|title=Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human [[RAD52]] gene in a cardiovascular cohort. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024686 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.10.003 | |||
}} | |||
==PPM1D== | |||
* {{medline-title | |||
|title=Detectible mosaic truncating [[PPM1D]] mutations, age and breast cancer risk. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30850729 | |||
|full-text-url=https://sci-hub.do/10.1038/s10038-019-0589-1 | |||
}} | |||
* {{medline-title | |||
|title=Age-related remodelling of oesophageal epithelia by mutated cancer drivers. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30602793 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0811-x | |||
}} | |||
==CYP7A1== | |||
* {{medline-title | |||
|title=Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396457 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681801 | |||
}} | |||
* {{medline-title | |||
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246 | |||
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128 | |||
}} | |||
==APPL2== | |||
* {{medline-title | |||
|title=The reversal effect of physical exercise on aging-related increases in [[APPL2]] content in skeletal muscle. | |||
|date=01.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30189216 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2018.09.006 | |||
}} | |||
* {{medline-title | |||
|title=Adaptor Protein [[APPL2]] Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28965332 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0785-y | |||
}} | |||
==ABCA1== | |||
* {{medline-title | |||
|title=Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension. | |||
|date=01.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109455 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.08.027 | |||
}} | |||
* {{medline-title | |||
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770 | |||
}} | |||
==MDH1== | |||
* {{medline-title | |||
|title=Oxidative Damage to the TCA Cycle Enzyme [[MDH1]] Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. | |||
|date=03.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32175745 | |||
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00861 | |||
}} | |||
* {{medline-title | |||
|title=Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977188 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850038 | |||
}} | |||
==CD22== | |||
* {{medline-title | |||
|title=[[CD22]] blockade restores homeostatic microglial phagocytosis in ageing brains. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944478 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6574119 | |||
}} | |||
* {{medline-title | |||
|title=Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624008 | |||
|full-text-url=https://sci-hub.do/10.24425/119039 | |||
}} | |||
==HSPA1A== | |||
* {{medline-title | |||
|title=Vitamin D3 treatment regulates apoptosis, antioxidant defense system, and DNA integrity in the epididymal sperm of an aged rat model. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566824 | |||
|full-text-url=https://sci-hub.do/10.1002/mrd.23280 | |||
}} | |||
* {{medline-title | |||
|title=The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells. | |||
|date=01.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269563 | |||
|full-text-url=https://sci-hub.do/10.1556/2060.105.2018.3.20 | |||
}} | |||
==HCRT== | |||
* {{medline-title | |||
|title=Age-related central regulation of orexin and [[NPY]] in the short-lived African killifish Nothobranchius furzeri. | |||
|date=15.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666646 | |||
|full-text-url=https://sci-hub.do/10.1002/cne.24638 | |||
}} | |||
==RRM2B== | |||
* {{medline-title | |||
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs. | |||
|date=15.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179 | |||
}} | |||
==INPP4B== | |||
* {{medline-title | |||
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748 | |||
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724 | |||
}} | |||
==PDGFRB== | |||
* {{medline-title | |||
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636 | |||
}} | |||
==CYP2R1== | |||
* {{medline-title | |||
|title=Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955863 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693043 | |||
}} | |||
==CIP2A== | |||
* {{medline-title | |||
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma. | |||
|date=08.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124 | |||
}} | |||
==ANGPTL4== | |||
* {{medline-title | |||
|title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301 | |||
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x | |||
}} | |||
==FMO3== | |||
* {{medline-title | |||
|title=Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28819071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697103 | |||
}} | |||
==WLS== | |||
* {{medline-title | |||
|title=Evaluation of three statistical prediction models for forensic age prediction based on DNA methylation. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477092 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.02.008 | |||
}} | |||
==BBS5== | |||
* {{medline-title | |||
|title=Progressive Characterization of Visual Phenotype in Bardet-Biedl Syndrome Mutant Mice. | |||
|date=01.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30901771 | |||
|full-text-url=https://sci-hub.do/10.1167/iovs.18-25210 | |||
}} | |||
==UCHL1== | |||
* {{medline-title | |||
|title=Abolishing [[UCHL1]]'s hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice. | |||
|date=04.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33159930 | |||
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2020.113524 | |||
}} | |||
==PLA2G6== | |||
* {{medline-title | |||
|title=Mutations in the Drosophila homolog of human [[PLA2G6]] give rise to age-dependent loss of psychomotor activity and neurodegeneration. | |||
|date=13.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29440694 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811537 | |||
}} | |||
==FMR1== | |||
* {{medline-title | |||
|title=Static and dynamic postural control deficits in aging fragile X mental retardation 1 ([[FMR1]]) gene premutation carriers. | |||
|date=21.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30665341 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341725 | |||
}} | |||
==MAP1A== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
==IL13== | |||
* {{medline-title | |||
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015 | |||
}} | |||
==DUSP8== | |||
* {{medline-title | |||
|title=MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31400088 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826124 | |||
}} | |||
==TNFSF15== | |||
* {{medline-title | |||
|title=Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269026 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.09.015 | |||
}} | |||
==FAR2== | |||
* {{medline-title | |||
|title=[[FAR2]] is associated with kidney disease in mice and humans. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29652635 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139637 | |||
}} | |||
==NOA1== | |||
* {{medline-title | |||
|title=The dependence of leaf senescence on the balance between 1-aminocyclopropane-1-carboxylate acid synthase 1 (ACS1)-catalysed ACC generation and nitric oxide-associated 1 (NOS1)-dependent NO accumulation in Arabidopsis. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30734982 | |||
|full-text-url=https://sci-hub.do/10.1111/plb.12970 | |||
}} | |||
==SPP1== | |||
* {{medline-title | |||
|title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781 | |||
}} | |||
==TOR2A== | |||
* {{medline-title | |||
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. | |||
|date=05.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244 | |||
}} | |||
==WFIKKN2== | |||
* {{medline-title | |||
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults. | |||
|date=01.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188 | |||
}} | |||
==ACMSD== | |||
* {{medline-title | |||
|title=De novo NAD synthesis enhances mitochondrial function and improves health. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30356218 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448761 | |||
}} | |||
==HSD3B2== | |||
* {{medline-title | |||
|title=11-Oxygenated C19 Steroids Do Not Decline With Age in Women. | |||
|date=01.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753518 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525564 | |||
}} | |||
==PREP== | |||
* {{medline-title | |||
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157 | |||
|full-text-url=https://sci-hub.do/10.1111/jbg.12299 | |||
}} | |||
==OSM== | |||
* {{medline-title | |||
|title=Age Differences in Sexual Minority Stress and the Importance of Friendship in Later Life. | |||
|date=04.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143546 | |||
|full-text-url=https://sci-hub.do/10.1080/07317115.2020.1836107 | |||
}} | |||
==UGT2B7== | |||
* {{medline-title | |||
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942 | |||
|full-text-url=https://sci-hub.do/10.1002/bdd.2181 | |||
}} | |||
==EDN1== | |||
* {{medline-title | |||
|title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812 | |||
|full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0 | |||
}} | |||
==NAIP== | |||
* {{medline-title | |||
|title=Protective effect of xanthohumol against age-related brain damage. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011 | |||
}} | |||
==PIK3C2A== | |||
* {{medline-title | |||
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 | |||
}} | |||
==NUCB2== | |||
* {{medline-title | |||
|title=Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise Killifish. | |||
|date=31.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31906085 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019235 | |||
}} | |||
==ACTR3B== | |||
* {{medline-title | |||
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720 | |||
}} | |||
==HES1== | |||
* {{medline-title | |||
|title=A Single-Cell Transcriptomic Atlas of Human Skin Aging. | |||
|date=23.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33238152 | |||
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2020.11.002 | |||
}} | |||
==DRD1== | |||
* {{medline-title | |||
|title=Impact of dopamine-related genetic variants on physical activity in old age - a cohort study. | |||
|date=24.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32448293 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245799 | |||
}} | |||
==PSMB8== | |||
* {{medline-title | |||
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748 | |||
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724 | |||
}} | |||
==GP6== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==AOX1== | |||
* {{medline-title | |||
|title=N1-Methylnicotinamide: An Anti-Ovarian Aging Hormetin? | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32711159 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101131 | |||
}} | |||
==MRO== | |||
* {{medline-title | |||
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats]. | |||
|date=08.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594 | |||
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110 | |||
}} | |||
==LRP1== | |||
* {{medline-title | |||
|title=Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268785 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255962 | |||
}} | |||
==RXRG== | |||
* {{medline-title | |||
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184 | |||
}} | |||
==GORAB== | |||
* {{medline-title | |||
|title=Examining tissue composition, whole-bone morphology and mechanical behavior of Gorab mice tibiae: A mouse model of premature aging. | |||
|date=08.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29108851 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695220 | |||
}} | |||
==PABPN1== | |||
* {{medline-title | |||
|title=Dysfunctional transcripts are formed by alternative polyadenylation in OPMD. | |||
|date=26.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088723 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650278 | |||
}} | |||
==CBX8== | |||
* {{medline-title | |||
|title=[[PIM1]]-catalyzed [[CBX8]] phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast. | |||
|date=27.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29763603 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.05.070 | |||
}} | |||
==BAG3== | |||
* {{medline-title | |||
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049 | |||
}} | |||
==KCNAB3== | |||
* {{medline-title | |||
|title=Tracking age-correlated DNA methylation markers in the young. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29933125 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.06.011 | |||
}} | |||
==SRSF3== | |||
* {{medline-title | |||
|title=Alternative polyadenylation dependent function of splicing factor [[SRSF3]] contributes to cellular senescence. | |||
|date=04.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30835716 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428108 | |||
}} | |||
==NGFR== | |||
* {{medline-title | |||
|title=Evidence for changing nerve growth factor signalling mechanisms during development, maturation and ageing in the rat molar pulp. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30099752 | |||
|full-text-url=https://sci-hub.do/10.1111/iej.12997 | |||
}} | |||
==COQ7== | |||
* {{medline-title | |||
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. | |||
|date=18.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522 | |||
}} | |||
==GPX2== | |||
* {{medline-title | |||
|title=RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells. | |||
|date=10.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020613 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639470 | |||
}} | |||
==PRKCH== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==FASN== | |||
* {{medline-title | |||
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009 | |||
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6 | |||
}} | |||
==SAT1== | |||
* {{medline-title | |||
|title=Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544364 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469548 | |||
}} | |||
==GADD45B== | |||
* {{medline-title | |||
|title=Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging? | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156709 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529819 | |||
}} | |||
==SALL1== | |||
* {{medline-title | |||
|title=[[SALL1]] functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex. | |||
|date=06.04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29625565 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889587 | |||
}} | |||
==LRP2== | |||
* {{medline-title | |||
|title=Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis. | |||
|date=27.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485812 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.11.003 | |||
}} | |||
==PDK4== | |||
* {{medline-title | |||
|title=Putrescine delays postovulatory aging of mouse oocytes by upregulating [[PDK4]] expression and improving mitochondrial activity. | |||
|date=16.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554191 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326651 | |||
}} | |||
==TRIM28== | |||
* {{medline-title | |||
|title=Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau. | |||
|date=04.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29863470 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993537 | |||
}} | |||
==RRAD== | |||
* {{medline-title | |||
|title=Pan-senescence transcriptome analysis identified [[RRAD]] as a marker and negative regulator of cellular senescence. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391675 | |||
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.10.457 | |||
}} | |||
==ECRG4== | |||
* {{medline-title | |||
|title=[[ECRG4]]: a new potential target in precision medicine. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003403 | |||
|full-text-url=https://sci-hub.do/10.1007/s11684-018-0637-9 | |||
}} | |||
==COL6A1== | |||
* {{medline-title | |||
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | |||
}} | |||
==FSTL1== | |||
* {{medline-title | |||
|title=Blocking the [[FSTL1]]-[[DIP2A]] Axis Improves Anti-tumor Immunity. | |||
|date=14.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30110636 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.07.043 | |||
}} | |||
==CREB5== | |||
* {{medline-title | |||
|title=Cellular senescence induces replication stress with almost no affect on DNA replication timing. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963964 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133336 | |||
}} | |||
==MTRR== | |||
* {{medline-title | |||
|title=One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208817 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.05.013 | |||
}} | |||
==FADD== | |||
* {{medline-title | |||
|title=Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal [[FADD]]. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30138765 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.07.014 | |||
}} | |||
==SND1== | |||
* {{medline-title | |||
|title=[Downregulation of [[SND1]] Expression Accelerates Cell Senescence of Human Diploid Fibroblasts 2BS via Modulating the SASP]. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32543144 | |||
|full-text-url=https://sci-hub.do/10.12182/20200560504 | |||
}} | |||
==DDR1== | |||
* {{medline-title | |||
|title=Age-related modifications of type I collagen impair [[DDR1]]-induced apoptosis in non-invasive breast carcinoma cells. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733741 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363044 | |||
}} | |||
==ST18== | |||
* {{medline-title | |||
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748 | |||
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724 | |||
}} | |||
==TGM2== | |||
* {{medline-title | |||
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004 | |||
}} | |||
==SP1== | |||
* {{medline-title | |||
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 | |||
}} | |||
==CIZ1== | |||
* {{medline-title | |||
|title=DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154038 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877805 | |||
}} | |||
==RORA== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==FOXP2== | |||
* {{medline-title | |||
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization. | |||
|date=06.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247 | |||
}} | |||
==STC2== | |||
* {{medline-title | |||
|title=Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and [[STC2]]. | |||
|date=05.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31761296 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904802 | |||
}} | |||
==CXCR5== | |||
* {{medline-title | |||
|title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses. | |||
|date=17.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542 | |||
}} | |||
==DDR2== | |||
* {{medline-title | |||
|title=Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073363 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833185 | |||
}} | |||
==DBH== | |||
* {{medline-title | |||
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915 | |||
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711 | |||
}} | |||
==NMUR1== | |||
* {{medline-title | |||
|title=[Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules]. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31685733 | |||
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00149 | |||
}} | |||
==TXN== | |||
* {{medline-title | |||
|title=Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29141658 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688691 | |||
}} | |||
==HJV== | |||
* {{medline-title | |||
|title=Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884219 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596404 | |||
}} | |||
==TP73== | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 | |||
}} | |||
==MICB== | |||
* {{medline-title | |||
|title=Genetic associations with age of menopause in familial longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937 | |||
}} | |||
==PTN== | |||
* {{medline-title | |||
|title=Connecting Metainflammation and Neuroinflammation Through the [[PTN]]-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31031625 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474308 | |||
}} | |||
==MCM3== | |||
* {{medline-title | |||
|title=Changes in [[MCM2]]-7 proteins at senescence. | |||
|date=27.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751 | |||
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062 | |||
}} | |||
==UCN== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==IGFBP7== | |||
* {{medline-title | |||
|title=Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31904196 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031646 | |||
}} | |||
==KLF2== | |||
* {{medline-title | |||
|title=[[KLF2]] induces the senescence of pancreatic cancer cells by cooperating with FOXO4 to upregulate p21. | |||
|date=01.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31866399 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2019.111784 | |||
}} | |||
==LIPA== | |||
* {{medline-title | |||
|title=Influence of Habitual Physical Behavior - Sleeping, Sedentarism, Physical Activity - On Bone Health in Community-Dwelling Older People. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31037056 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476278 | |||
}} | |||
==SMARCB1== | |||
* {{medline-title | |||
|title=High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer. | |||
|date=17.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29045843 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2017.09.085 | |||
}} | |||
==IP6K1== | |||
* {{medline-title | |||
|title=The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552262 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746962 | |||
}} | |||
==NBR1== | |||
* {{medline-title | |||
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049 | |||
}} | |||
==PPP2R3C== | |||
* {{medline-title | |||
|title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667 | |||
}} | |||
==CFH== | |||
* {{medline-title | |||
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. | |||
|date=13.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230 | |||
}} | |||
==USP8== | |||
* {{medline-title | |||
|title=Inhibition of the deubiquitinase [[USP8]] corrects a Drosophila [[PINK1]] model of mitochondria dysfunction. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988163 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467245 | |||
}} | |||
==PRNP== | |||
* {{medline-title | |||
|title=Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32516343 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282622 | |||
}} | |||
==SV2B== | |||
* {{medline-title | |||
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247 | |||
}} | |||
==CCN4== | |||
* {{medline-title | |||
|title=CCN proteins as potential actionable targets in scleroderma. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30329180 | |||
|full-text-url=https://sci-hub.do/10.1111/exd.13806 | |||
}} | |||
==BANF1== | |||
* {{medline-title | |||
|title=An additional case of Néstor-Guillermo progeria syndrome diagnosed in early childhood. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32783369 | |||
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.61777 | |||
}} | |||
==TNP2== | |||
* {{medline-title | |||
|title=Cytological and molecular aspects of the ageing sperm. | |||
|date=01.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142 | |||
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357 | |||
}} | |||
==SMYD2== | |||
* {{medline-title | |||
|title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115 | |||
}} | |||
==GDF9== | |||
* {{medline-title | |||
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. | |||
|date=18.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463 | |||
}} | |||
==KLF5== | |||
* {{medline-title | |||
|title=[[EGR1]] promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling. | |||
|date=01.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201921 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.06.010 | |||
}} | |||
==BTC== | |||
* {{medline-title | |||
|title=Behavioral tagging and capture: long-term memory decline in middle-aged rats. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29609080 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964067 | |||
}} | |||
==BARD1== | |||
* {{medline-title | |||
|title=BRCA1 and [[BARD1]] mediate apoptotic resistance but not longevity upon mitochondrial stress in [i]Caenorhabditis elegans[/i]. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30366941 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280797 | |||
}} | |||
==PEBP1== | |||
* {{medline-title | |||
|title=[i]Drosophila[/i] [[PEBP1]] inhibits intestinal stem cell aging via suppression of ERK pathway. | |||
|date=06.04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719584 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915051 | |||
}} | |||
==NMI== | |||
* {{medline-title | |||
|title=Age-Dependent Control of Shoulder Muscles During a Reach-and-Lift Task. | |||
|date=10.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31825888 | |||
|full-text-url=https://sci-hub.do/10.1123/japa.2019-0055 | |||
}} | |||
==TAF7== | |||
* {{medline-title | |||
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis. | |||
|date=22.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986 | |||
}} | |||
==NLRX1== | |||
* {{medline-title | |||
|title=NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells. | |||
|date=26.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482578 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828065 | |||
}} | |||
==HHLA2== | |||
* {{medline-title | |||
|title=Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30768970 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jtho.2019.01.024 | |||
}} | |||
==WT1== | |||
* {{medline-title | |||
|title=Age and weight at first mating affects plasma leptin concentration but no effects on reproductive performance of gilts. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31602307 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778857 | |||
}} | |||
==PPARG== | |||
* {{medline-title | |||
|title=The [[PPARG]] Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity. | |||
|date=04-06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29116943 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938164 | |||
}} | |||
==PTK7== | |||
* {{medline-title | |||
|title=Innate and adaptive immune dysregulation in critically ill ICU patients. | |||
|date=05.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948 | |||
}} | |||
==VASH1== | |||
* {{medline-title | |||
|title=Double-Face of Vasohibin-1 for the Maintenance of Vascular Homeostasis and Healthy Longevity. | |||
|date=01.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29398681 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005230 | |||
}} | |||
==TRAV27== | |||
* {{medline-title | |||
|title=Perturbed CD8 T cell immunity across universal influenza epitopes in the elderly. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928269 | |||
|full-text-url=https://sci-hub.do/10.1189/jlb.5MA0517-207R | |||
}} | |||
==ACSL5== | |||
* {{medline-title | |||
|title=Ageing sensitized by iPLA β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888832 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2017.09.001 | |||
}} | |||
==HNRNPA0== | |||
* {{medline-title | |||
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819 | |||
}} | |||
==MCF2L== | |||
* {{medline-title | |||
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | |||
|date=25.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | |||
}} | |||
==ALOX12== | |||
* {{medline-title | |||
|title=Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer. | |||
|date=15.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32265301 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242692 | |||
}} | |||
==RARB== | |||
* {{medline-title | |||
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896 | |||
}} | |||
==COL1A1== | |||
* {{medline-title | |||
|title=Remodeling process in bone of aged rats in response to resistance training. | |||
|date=01.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593709 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118008 | |||
}} | |||
==ATF2== | |||
* {{medline-title | |||
|title=Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium. | |||
|date=01.04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360953 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915954 | |||
}} | |||
==USF2== | |||
* {{medline-title | |||
|title=Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice. | |||
|date=15.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30084918 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454504 | |||
}} | |||
==CLN3== | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
==GNAQ== | |||
* {{medline-title | |||
|title=[[GNAQ]] expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31680437 | |||
|full-text-url=https://sci-hub.do/10.1111/pcmr.12843 | |||
}} | |||
==MC1R== | |||
* {{medline-title | |||
|title=In vitro behavior and UV response of melanocytes derived from carriers of [[[[CDKN2A]]]] mutations and [[MC1R]] variants. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117292 | |||
|full-text-url=https://sci-hub.do/10.1111/pcmr.12732 | |||
}} | |||
==ERCC5== | |||
* {{medline-title | |||
|title=Identification of a [[ERCC5]] c.2333T>C (L778P) Variant in Two Tunisian Siblings With Mild Xeroderma Pigmentosum Phenotype. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30838033 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383105 | |||
}} | |||
==S1PR3== | |||
* {{medline-title | |||
|title=Sexual dimorphism of metabolic and vascular dysfunction in aged mice and those lacking the sphingosine 1-phosphate receptor 3. | |||
|date=01.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28943478 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.013 | |||
}} | |||
==SATB2== | |||
* {{medline-title | |||
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.28223 | |||
}} | |||
==SELENOK== | |||
* {{medline-title | |||
|title=Dietary selenium deficiency and supplementation differentially modulate the expression of two ER-resident selenoproteins (selenoprotein K and selenoprotein M) in the ovaries of aged mice: Preliminary data. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736983 | |||
|full-text-url=https://sci-hub.do/10.1016/j.repbio.2020.07.006 | |||
}} | |||
==GAB2== | |||
* {{medline-title | |||
|title=Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936. | |||
|date=01.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29207374 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764388 | |||
}} | |||
==ITGA3== | |||
* {{medline-title | |||
|title=A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells. | |||
|date=17.08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32807231 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430027 | |||
}} | |||
==NRM== | |||
* {{medline-title | |||
|title=Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31445185 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192097 | |||
}} | |||
==PRM2== | |||
* {{medline-title | |||
|title=Cytological and molecular aspects of the ageing sperm. | |||
|date=01.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142 | |||
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357 | |||
}} | |||
==DLAT== | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
==ACAT2== | |||
* {{medline-title | |||
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. | |||
|date=15.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823 | |||
}} | |||
==UBTF== | |||
* {{medline-title | |||
|title=Age-associated dysregulation of protein metabolism in the mammalian oocyte. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994181 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676066 | |||
}} | |||
==WFIKKN1== | |||
* {{medline-title | |||
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults. | |||
|date=01.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188 | |||
}} | |||
==GSTM3== | |||
* {{medline-title | |||
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | |||
}} | |||
==YES1== | |||
* {{medline-title | |||
|title=Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies. | |||
|date=20.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30341976 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224233 | |||
}} | |||
==GSN== | |||
* {{medline-title | |||
|title=Oral administration of alcalase potato protein hydrolysate-APPH attenuates high fat diet-induced cardiac complications via TGF-β/[[GSN]] axis in aging rats. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30240538 | |||
|full-text-url=https://sci-hub.do/10.1002/tox.22651 | |||
}} | |||
==RB1== | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 | |||
}} | |||
==MR1== | |||
* {{medline-title | |||
|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826 | |||
}} | |||
==LRP8== | |||
* {{medline-title | |||
|title=SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating [[LRP8]] and ApoE. | |||
|date=02.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31269452 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.06.002 | |||
}} | |||
==HLA-DMA== | |||
* {{medline-title | |||
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | |||
}} | |||
==OOEP== | |||
* {{medline-title | |||
|title=Maternal gene [i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes. | |||
|date=18.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955025 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085769 | |||
}} | |||
==ACAN== | |||
* {{medline-title | |||
|title=MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30987676 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769 | |||
}} | |||
==SOX13== | |||
* {{medline-title | |||
|title=In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520345 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09834-1 | |||
}} | |||
==TOP1== | |||
* {{medline-title | |||
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis. | |||
|date=12.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701 | |||
}} | |||
==ST6GAL1== | |||
* {{medline-title | |||
|title=Glycobiology of Aging. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30779020 | |||
|full-text-url=https://sci-hub.do/10.1007/978-981-13-2835-0_17 | |||
}} | |||
==HSP90AA1== | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
==ZNF467== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==CYP26A1== | |||
* {{medline-title | |||
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. | |||
|date=08.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028 | |||
}} | |||
==SDC4== | |||
* {{medline-title | |||
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. | |||
|date=01.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677 | |||
}} | |||
==RPA2== | |||
* {{medline-title | |||
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015 | |||
}} | |||
==HSPG2== | |||
* {{medline-title | |||
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13091 | |||
}} | |||
==NEK2== | |||
* {{medline-title | |||
|title=Upregulation of [[FOXM1]] leads to diminished drug sensitivity in myeloma. | |||
|date=21.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463534 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249818 | |||
}} | |||
==MAOA== | |||
* {{medline-title | |||
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. | |||
|date=05.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149 | |||
}} | |||
==HSPB1== | |||
* {{medline-title | |||
|title=The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102684 | |||
|full-text-url=https://sci-hub.do/10.1016/j.diabres.2019.05.009 | |||
}} | |||
==LTF== | |||
* {{medline-title | |||
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171 | |||
}} | |||
==EID3== | |||
* {{medline-title | |||
|title=Upregulation of [[EID3]] sensitizes breast cancer cells to ionizing radiation-induced cellular senescence. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30114644 | |||
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.08.022 | |||
}} | |||
==GRM3== | |||
* {{medline-title | |||
|title=Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32203495 | |||
|full-text-url=https://sci-hub.do/10.1038/s41593-020-0604-z | |||
}} | |||
==USP7== | |||
* {{medline-title | |||
|title=Deubiquitinase [[USP7]] regulates [i]Drosophila[/i] aging through ubiquitination and autophagy. | |||
|date=20.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33221768 | |||
|full-text-url=https://sci-hub.do/10.18632/aging.104067 | |||
}} | |||
==JAK3== | |||
* {{medline-title | |||
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006 | |||
}} | |||
==ULK2== | |||
* {{medline-title | |||
|title=miR-26a suppresses autophagy in swine Sertoli cells by targeting [[ULK2]]. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29761550 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13177 | |||
}} | |||
==SPHK1== | |||
* {{medline-title | |||
|title=Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30997640 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425817 | |||
}} | |||
==CTC1== | |||
* {{medline-title | |||
|title=[[CTC1]]-[[STN1]] coordinates G- and C-strand synthesis to regulate telomere length. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774655 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479 | |||
}} | |||
==CXCL16== | |||
* {{medline-title | |||
|title=[[CXCR6]] Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and [[CD4]] T-Cell-Dependent Control of Senescence. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710528 | |||
|full-text-url=https://sci-hub.do/10.1053/j.gastro.2019.01.247 | |||
}} | |||
==ENTPD7== | |||
* {{medline-title | |||
|title=Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 ([[ENTPD7]]). | |||
|date=23.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31443651 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708200 | |||
}} | |||
==P2RY10== | |||
* {{medline-title | |||
|title=Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury. | |||
|date=12.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189983 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561964 | |||
}} | |||
==IFNG== | |||
* {{medline-title | |||
|title=Glutathione Peroxidase 3 Delivered by hiPSC-[[MSC]]s Ameliorated Hepatic IR Injury via Inhibition of Hepatic Senescence. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29290803 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743470 | |||
}} | |||
==PTTG1== | |||
* {{medline-title | |||
|title=[Down-regulated [[PTTG1]] expression promotes the senescence of human prostate cancer LNCaP-AI]. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32216239 | |||
}} | |||
==CYP1B1== | |||
* {{medline-title | |||
|title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510 | |||
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3 | |||
}} | |||
==MCM6== | |||
* {{medline-title | |||
|title=Changes in [[MCM2]]-7 proteins at senescence. | |||
|date=27.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751 | |||
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062 | |||
}} | |||
==LMX1A== | |||
* {{medline-title | |||
|title=Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain. | |||
|date=13.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30318292 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234859 | |||
}} | |||
==POLL== | |||
* {{medline-title | |||
|title=Temporal trends in loss of life expectancy after a cancer diagnosis among the Australian population. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32062407 | |||
|full-text-url=https://sci-hub.do/10.1016/j.canep.2020.101686 | |||
}} | |||
==TGFB1== | |||
* {{medline-title | |||
|title=Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28812215 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665708 | |||
}} | |||
==IFIT1== | |||
* {{medline-title | |||
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062 | |||
}} | |||
==UBE2E3== | |||
* {{medline-title | |||
|title=Loss of the ubiquitin conjugating enzyme [[UBE2E3]] induces cellular senescence. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29879550 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007080 | |||
}} | |||
==PAX7== | |||
* {{medline-title | |||
|title=Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30006671 | |||
|full-text-url=https://sci-hub.do/10.1007/s00421-018-3943-7 | |||
}} | |||
==PTPRR== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==ABCC9== | |||
* {{medline-title | |||
|title=TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30682540 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696921 | |||
}} | |||
==NFATC1== | |||
* {{medline-title | |||
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. | |||
|date=02.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654 | |||
}} | |||
==EIF4E== | |||
* {{medline-title | |||
|title=Transcriptomic evidence that insulin signalling pathway regulates the ageing of subterranean termite castes. | |||
|date=18.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424344 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235038 | |||
}} | |||
==SCAMP4== | |||
* {{medline-title | |||
|title=[[SCAMP4]] enhances the senescent cell secretome. | |||
|date=01.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967290 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075036 | |||
}} | |||
==MYSM1== | |||
* {{medline-title | |||
|title=[[MYSM1]] Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33240758 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675055 | |||
}} | |||
==INHBA== | |||
* {{medline-title | |||
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13091 | |||
}} | |||
==BTG1== | |||
* {{medline-title | |||
|title=Tumor cell escape from therapy-induced senescence. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576620 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bcp.2018.12.013 | |||
}} | |||
==OMD== | |||
* {{medline-title | |||
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. | |||
|date=06.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057 | |||
}} | |||
==IMMP2L== | |||
* {{medline-title | |||
|title=Switching off [[IMMP2L]] signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808012 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993829 | |||
}} | |||
==TRIB2== | |||
* {{medline-title | |||
|title=[[TRIB2]] functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling. | |||
|date=12.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541550 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291992 | |||
}} | |||
==ABLIM3== | |||
* {{medline-title | |||
|title=Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29529016 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893385 | |||
}} | |||
==USF1== | |||
* {{medline-title | |||
|title=The rs2516839 variation of [[USF1]] gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+ study. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30203836 | |||
|full-text-url=https://sci-hub.do/10.1111/ahg.12282 | |||
}} | |||
==ASMT== | |||
* {{medline-title | |||
|title=The influence of ageing on the extrapineal melatonin synthetic pathway. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29906492 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.06.010 | |||
}} | |||
==ERBB4== | |||
* {{medline-title | |||
|title=Overexpression of [[ERBB4]] rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566395 | |||
|full-text-url=https://sci-hub.do/10.1096/fj.201801690R | |||
}} | |||
==CHRNE== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==CPT1B== | |||
* {{medline-title | |||
|title=Effects of carnitine palmitoyltransferases on cancer cellular senescence. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30070697 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.27042 | |||
}} | |||
==CNP== | |||
* {{medline-title | |||
|title=Environmental Enrichment Elicits a Transient Rise of Bioactive C-Type Natriuretic Peptide in Young but Not Aged Rats. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30072880 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060231 | |||
}} | |||
==MCAT== | |||
* {{medline-title | |||
|title=Small molecules as therapeutic drugs for Alzheimer's disease. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30877034 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510253 | |||
}} | |||
==ALKBH2== | |||
* {{medline-title | |||
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756 | |||
}} | |||
==SELENOP== | |||
* {{medline-title | |||
|title=Analyses of Selenotranscriptomes and Selenium Concentrations in Response to Dietary Selenium Deficiency and Age Reveal Common and Distinct Patterns by Tissue and Sex in Telomere-Dysfunctional Mice. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28855418 | |||
|full-text-url=https://sci-hub.do/10.3945/jn.117.247775 | |||
}} | |||
==ELF3== | |||
* {{medline-title | |||
|title=High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in [i]Arabidopsis[/i]. | |||
|date=31.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32732458 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398796 | |||
}} | |||
==SCN9A== | |||
* {{medline-title | |||
|title=The [[SCN9A]] channel and plasma membrane depolarization promote cellular senescence through Rb pathway. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29446526 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946064 | |||
}} | |||
==ZBTB16== | |||
* {{medline-title | |||
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.26231 | |||
}} | |||
==NDUFV2== | |||
* {{medline-title | |||
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205 | |||
}} | |||
==NEFM== | |||
* {{medline-title | |||
|title=Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30927131 | |||
|full-text-url=https://sci-hub.do/10.1007/s10735-019-09820-4 | |||
}} | |||
==GPC1== | |||
* {{medline-title | |||
|title=Decreased expression of [[GPC1]] in human skin keratinocytes and epidermis during ageing. | |||
|date=15.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31430521 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110693 | |||
}} | |||
==NEIL1== | |||
* {{medline-title | |||
|title=[[NEIL1]] stimulates neurogenesis and suppresses neuroinflammation after stress. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175982 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526462 | |||
}} | |||
==SRY== | |||
* {{medline-title | |||
|title=Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics. | |||
|date=26.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29371932 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768349 | |||
}} | |||
==SCGN== | |||
* {{medline-title | |||
|title=Detection and evaluation of DNA methylation markers found at [[SCGN]] and [[KLF14]] loci to estimate human age. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854399 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011 | |||
}} | |||
==PYCR1== | |||
* {{medline-title | |||
|title=A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals [[POSTN]] As a New Element in Proline Metabolic Disorder. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574417 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284769 | |||
}} | |||
==PGLS== | |||
* {{medline-title | |||
|title=547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates. | |||
|date=28.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779658 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883628 | |||
}} | |||
==CASP3== | |||
* {{medline-title | |||
|title=Does cartilage ERα overexpression correlate with osteoarthritic chondrosenescence? Indications from [i]Labisia pumila[/i] OA mitigation. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31502578 | |||
}} | |||
==CLEC4E== | |||
* {{medline-title | |||
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569 | |||
}} | |||
==GRID1== | |||
* {{medline-title | |||
|title=Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109663 | |||
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2020.02.005 | |||
}} | |||
==IPMK== | |||
* {{medline-title | |||
|title=Inositol Polyphosphate Multikinase ([i][[IPMK]][/i]), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity. | |||
|date=08.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30744060 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410091 | |||
}} | |||
==EIF2B1== | |||
* {{medline-title | |||
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 | |||
}} | |||
==WNK1== | |||
* {{medline-title | |||
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534 | |||
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4 | |||
}} | |||
==BCL2L11== | |||
* {{medline-title | |||
|title=miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074095 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.28862 | |||
}} | |||
==ARID5A== | |||
* {{medline-title | |||
|title=Differentially regulated gene expression in quiescence versus senescence and identification of [[ARID5A]] as a quiescence associated marker. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29044508 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.26227 | |||
}} | |||
==SELENOW== | |||
* {{medline-title | |||
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511 | |||
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9 | |||
}} | |||
==PON1== | |||
* {{medline-title | |||
|title=Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview. | |||
|date=02.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31052559 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562914 | |||
}} | |||
==PRKDC== | |||
* {{medline-title | |||
|title=DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis. | |||
|date=29.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31464599 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716822 | |||
}} | |||
==MAPK11== | |||
* {{medline-title | |||
|title=lncRNA ENSMUST00000134285 Increases [[MAPK11]] Activity, Regulating Aging-Related Myocardial Apoptosis. | |||
|date=09.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415197 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/gly020 | |||
}} | |||
==CCNA2== | |||
* {{medline-title | |||
|title=Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan. | |||
|date=31.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881094 | |||
}} | |||
==EPHA2== | |||
* {{medline-title | |||
|title=Germ-line and somatic [[EPHA2]] coding variants in lens aging and cataract. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29267365 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739433 | |||
}} | |||
==DLGAP2== | |||
* {{medline-title | |||
|title=Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. | |||
|date=01.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32877673 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502175 | |||
}} | |||
==PIGR== | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
==STK3== | |||
* {{medline-title | |||
|title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. | |||
|date=11.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934 | |||
}} | |||
==CARF== | |||
* {{medline-title | |||
|title=Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential. | |||
|date=22.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31112603 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/glz077 | |||
}} | |||
==MAP2K3== | |||
* {{medline-title | |||
|title=Associations of [i][[MAP2K3]][/i] Gene Variants With Superior Memory in SuperAgers. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896098 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987172 | |||
}} | |||
==IRF1== | |||
* {{medline-title | |||
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062 | |||
}} | |||
==ALK== | |||
* {{medline-title | |||
|title=Catalog of Lung Cancer Gene Mutations Among Chinese Patients. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850378 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417348 | |||
}} | |||
==RSF1== | |||
* {{medline-title | |||
|title=The SR proteins SF2 and [[RBP1]] regulate triglyceride storage in the fat body of Drosophila. | |||
|date=27.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277943 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.151 | |||
}} | |||
==CDC25A== | |||
* {{medline-title | |||
|title=Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage. | |||
|date=10.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600899 | |||
}} | |||
==P4HA3== | |||
* {{medline-title | |||
|title=Age-associated genes in human mammary gland drive human breast cancer progression. | |||
|date=15.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32539762 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294649 | |||
}} | |||
==SLC15A2== | |||
* {{medline-title | |||
|title=Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019300 | |||
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3413-x | |||
}} | |||
==CREB1== | |||
* {{medline-title | |||
|title=Arginine Methyltransferase [[PRMT8]] Provides Cellular Stress Tolerance in Aging Motoneurons. | |||
|date=29.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054395 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113905 | |||
}} | |||
==CUX1== | |||
* {{medline-title | |||
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 | |||
}} | |||
==APOC3== | |||
* {{medline-title | |||
|title=Positional Obstructive Sleep Apnea Syndrome in Elderly Patients. | |||
|date=10.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32050596 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042812 | |||
}} | |||
==CBX4== | |||
* {{medline-title | |||
|title=Maintenance of Nucleolar Homeostasis by [[CBX4]] Alleviates Senescence and Osteoarthritis. | |||
|date=26.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30917318 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.02.088 | |||
}} | |||
==PLK1== | |||
* {{medline-title | |||
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804 | |||
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011 | |||
}} | |||
==RUNX3== | |||
* {{medline-title | |||
|title=circLARP4 induces cellular senescence through regulating miR-761/[[RUNX3]]/p53/p21 signaling in hepatocellular carcinoma. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30520539 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361555 | |||
}} | |||
==CCND3== | |||
* {{medline-title | |||
|title=The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. | |||
|date=29.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32727592 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392710 | |||
}} | |||
==LDLR== | |||
* {{medline-title | |||
|title=Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29903737 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092113 | |||
}} | |||
==SUN2== | |||
* {{medline-title | |||
|title=Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging. | |||
|date=26.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808750 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397528 | |||
}} | |||
==PPA2== | |||
* {{medline-title | |||
|title=Characterization of long living yeast deletion mutants that lack mitochondrial metabolism genes DSS1, [[PPA2]] and AFG3. | |||
|date=20.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31082499 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2019.05.001 | |||
}} | |||
==TXNDC5== | |||
* {{medline-title | |||
|title=Genetic associations with age of menopause in familial longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937 | |||
}} | |||
==MAP4K3== | |||
* {{medline-title | |||
|title=[[MAP4K3]]/GLK in autoimmune disease, cancer and aging. | |||
|date=22.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31640697 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806545 | |||
}} | |||
==NKX2-5== | |||
* {{medline-title | |||
|title=Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart. | |||
|date=07.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30663680 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207148 | |||
}} | |||
==TJP1== | |||
* {{medline-title | |||
|title=Morphological and immunohistochemical characteristics of the equine corneal epithelium. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767359 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900071 | |||
}} | |||
==MAS1== | |||
* {{medline-title | |||
|title=AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation. | |||
|date=17.04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667931 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940107 | |||
}} | |||
==IL4== | |||
* {{medline-title | |||
|title=Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia. | |||
|date=01.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122767 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756472 | |||
}} | |||
==TRIM27== | |||
* {{medline-title | |||
|title=[[TRIM27]] Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination. | |||
|date=04.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33251042 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666371 | |||
}} | |||
==FBXO46== | |||
* {{medline-title | |||
|title=The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence. | |||
|date=19.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945 | |||
}} | |||
==MATN3== | |||
* {{medline-title | |||
|title=Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis. | |||
|date=19.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31963938 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013758 | |||
}} | |||
==TRIB3== | |||
* {{medline-title | |||
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528 | |||
}} | |||
==BCL11B== | |||
* {{medline-title | |||
|title=Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360511 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989724 | |||
}} | |||
==TRPC1== | |||
* {{medline-title | |||
|title=Ca entry via [[TRPC1]] is essential for cellular differentiation and modulates secretion via the SNARE complex. | |||
|date=01.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182642 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397 | |||
}} | |||
==DEPTOR== | |||
* {{medline-title | |||
|title=[[DEPTOR]] at the Nexus of Cancer, Metabolism, and Immunity. | |||
|date=01.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897294 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335100 | |||
}} | |||
==SYNJ2== | |||
* {{medline-title | |||
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | |||
|date=25.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | |||
}} | |||
==RNF144A== | |||
* {{medline-title | |||
|title=Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31280115 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732230 | |||
}} | |||
==PKD1== | |||
* {{medline-title | |||
|title=The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response. | |||
|date=16.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29420297 | |||
|full-text-url=https://sci-hub.do/10.1242/jcs.207217 | |||
}} | |||
==PDHB== | |||
* {{medline-title | |||
|title=Neuron-specific knockdown of Drosophila [[PDHB]] induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting. | |||
|date=15.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501567 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.02.035 | |||
}} | |||
==NLRP1== | |||
* {{medline-title | |||
|title=NADPH oxidase 2-mediated [[NLRP1]] inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677569 | |||
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2019.01.025 | |||
}} | |||
==GYS2== | |||
* {{medline-title | |||
|title=In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986936 | |||
|full-text-url=https://sci-hub.do/10.1111/jpn.12831 | |||
}} | |||
==MS4A1== | |||
* {{medline-title | |||
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. | |||
|date=19.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985 | |||
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052 | |||
}} | |||
==LPAR3== | |||
* {{medline-title | |||
|title=Upregulated microRNA-15b alleviates ovarian cancer through inhitbition of the PI3K/Akt pathway by targeting [[LPAR3]]. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140597 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.28799 | |||
}} | |||
==DYRK1A== | |||
* {{medline-title | |||
|title=Altered age-linked regulation of plasma [[DYRK1A]] in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32642550 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331462 | |||
}} | |||
==HSD17B14== | |||
* {{medline-title | |||
|title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510 | |||
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3 | |||
}} | |||
==GNPAT== | |||
* {{medline-title | |||
|title=Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30128650 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1307-2 | |||
}} | |||
==SMAD1== | |||
* {{medline-title | |||
|title=TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands. | |||
|date=26.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779094 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928867 | |||
}} | |||
==PDE10A== | |||
* {{medline-title | |||
|title=Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175000 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732030 | |||
}} | |||
==ATXN1== | |||
* {{medline-title | |||
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201 | |||
}} | |||
==KCTD12== | |||
* {{medline-title | |||
|title=The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32970748 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514036 | |||
}} | |||
==PHB== | |||
* {{medline-title | |||
|title=Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30674441 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412871 | |||
}} | |||
==CYP26B1== | |||
* {{medline-title | |||
|title=Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia. | |||
|date=20.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32385093 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244205 | |||
}} | |||
==ATXN3== | |||
* {{medline-title | |||
|title=Rescue of [[ATXN3]] neuronal toxicity in [i]Caenorhabditis[/i][i]elegans[/i] by chemical modification of endoplasmic reticulum stress. | |||
|date=19.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29061563 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769603 | |||
}} | |||
==PCMTD1== | |||
* {{medline-title | |||
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157 | |||
|full-text-url=https://sci-hub.do/10.1111/jbg.12299 | |||
}} | |||
==GCAT== | |||
* {{medline-title | |||
|title=Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis. | |||
|date=03.04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29551589 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2018.02.004 | |||
}} | |||
==KDM4A== | |||
* {{medline-title | |||
|title=Structure-Based Discovery of a Selective [[KDM5A]] Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines. | |||
|date=15.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30650517 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360022 | |||
}} | |||
==TBC1D1== | |||
* {{medline-title | |||
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 | |||
}} | |||
==FER== | |||
* {{medline-title | |||
|title=Tracking the recognition of static and dynamic facial expressions of emotion across the life span. | |||
|date=04.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30208425 | |||
|full-text-url=https://sci-hub.do/10.1167/18.9.5 | |||
}} | |||
==MAP3K5== | |||
* {{medline-title | |||
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. | |||
|date=08.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033 | |||
}} | |||
==KLB== | |||
* {{medline-title | |||
|title=Infants Uniquely Express High Levels of [[RBM3]] and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399610 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311128 | |||
}} | |||
==CHEK2== | |||
* {{medline-title | |||
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. | |||
|date=20.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988 | |||
}} | |||
==RBM3== | |||
* {{medline-title | |||
|title=Infants Uniquely Express High Levels of [[RBM3]] and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399610 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311128 | |||
}} | |||
==TP53INP1== | |||
* {{medline-title | |||
|title=[[TP53INP1]] deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling. | |||
|date=02.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559202 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320535 | |||
}} | |||
==FOXD1== | |||
* {{medline-title | |||
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]]. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541 | |||
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y | |||
}} | |||
==ALDH3A1== | |||
* {{medline-title | |||
|title=Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs). | |||
|date=13.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760648 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382415 | |||
}} | |||
==GRIN2B== | |||
* {{medline-title | |||
|title=Medial temporal lobe atrophy relates more strongly to sleep-wake rhythm fragmentation than to age or any other known risk. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29864525 | |||
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2018.05.017 | |||
}} | |||
==MCM4== | |||
* {{medline-title | |||
|title=Changes in [[MCM2]]-7 proteins at senescence. | |||
|date=27.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751 | |||
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062 | |||
}} | |||
==ZNF207== | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
==MPST== | |||
* {{medline-title | |||
|title=Methionine restriction leads to hyperhomocysteinemia and alters hepatic H S production capacity in Fischer-344 rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30367932 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.10.004 | |||
}} | |||
==TPH1== | |||
* {{medline-title | |||
|title=[i]Lactobacillus plantarum[/i] DR7 improved brain health in aging rats via the serotonin, inflammatory and apoptosis pathways. | |||
|date=02.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33245015 | |||
|full-text-url=https://sci-hub.do/10.3920/BM2019.0200 | |||
}} | |||
==NRXN3== | |||
* {{medline-title | |||
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205 | |||
}} | |||
==SDC3== | |||
* {{medline-title | |||
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. | |||
|date=01.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677 | |||
}} | |||
==HLA-DQB1== | |||
* {{medline-title | |||
|title=Identification of new genetic variants of [[HLA-DQB1]] associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population. | |||
|date=10.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129831 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723689 | |||
}} | |||
==APLP2== | |||
* {{medline-title | |||
|title=Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362021 | |||
|full-text-url=https://sci-hub.do/10.1007/s11064-018-2669-6 | |||
}} | |||
==EZR== | |||
* {{medline-title | |||
|title=Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29245059 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801041 | |||
}} | |||
==RAD51C== | |||
* {{medline-title | |||
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815 | |||
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013 | |||
}} | |||
==GPBAR1== | |||
* {{medline-title | |||
|title=Activation of the bile acid receptor [[GPBAR1]] (TGR5) ameliorates interleukin-1β (IL-1β)- induced chondrocytes senescence. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119246 | |||
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.06.154 | |||
}} | |||
==MS4A6A== | |||
* {{medline-title | |||
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. | |||
|date=28.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389 | |||
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049 | |||
}} | |||
==UCN3== | |||
* {{medline-title | |||
|title=Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise-induced threshold shift. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31270820 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852351 | |||
}} | |||
==CTSS== | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
==MECOM== | |||
* {{medline-title | |||
|title=Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603369 | |||
|full-text-url=https://sci-hub.do/10.1111/jgh.14149 | |||
}} | |||
==CA12== | |||
* {{medline-title | |||
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. | |||
|date=26.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307 | |||
}} | |||
==SDHB== | |||
* {{medline-title | |||
|title=Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. | |||
|date=12.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32059608 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074517 | |||
}} | |||
==DUSP1== | |||
* {{medline-title | |||
|title=miR-1468-3p Promotes Aging-Related Cardiac Fibrosis. | |||
|date=05.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32348937 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191129 | |||
}} | |||
==EVL== | |||
* {{medline-title | |||
|title=Health Years in Total: A New Health Objective Function for Cost-Effectiveness Analysis. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31952678 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jval.2019.10.014 | |||
}} | |||
==PRKN== | |||
* {{medline-title | |||
|title=[[PRKN]]-regulated mitophagy and cellular senescence during COPD pathogenesis. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30290714 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351145 | |||
}} | |||
==BNC1== | |||
* {{medline-title | |||
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis. | |||
|date=22.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986 | |||
}} | |||
==SMN1== | |||
* {{medline-title | |||
|title=Changing respiratory expectations with the new disease trajectory of nusinersen treated spinal muscular atrophy [SMA] type 1. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414815 | |||
|full-text-url=https://sci-hub.do/10.1016/j.prrv.2018.07.002 | |||
}} | |||
==PDE9A== | |||
* {{medline-title | |||
|title=Identification of new [[PDE9A]] isoforms and how their expression and subcellular compartmentalization in the brain change across the life span. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29505961 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871571 | |||
}} | |||
==EXD2== | |||
* {{medline-title | |||
|title=[[EXD2]] governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29335528 | |||
|full-text-url=https://sci-hub.do/10.1038/s41556-017-0016-9 | |||
}} | |||
==GOT1== | |||
* {{medline-title | |||
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205 | |||
}} | |||
==OGA== | |||
* {{medline-title | |||
|title=NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase. | |||
|date=19.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31747588 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.10.053 | |||
}} | |||
==PRRX1== | |||
* {{medline-title | |||
|title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862 | |||
}} | |||
==TINF2== | |||
* {{medline-title | |||
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655 | |||
}} | |||
==USP15== | |||
* {{medline-title | |||
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i]. | |||
|date=29.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047 | |||
}} | |||
==LGALS3== | |||
* {{medline-title | |||
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325 | |||
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217 | |||
}} | |||
==ATP6V0C== | |||
* {{medline-title | |||
|title=A pH probe inhibits senescence in mesenchymal stem cells. | |||
|date=07.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523 | |||
}} | |||
==ARID1B== | |||
* {{medline-title | |||
|title=A 69-year-old woman with Coffin-Siris syndrome. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055038 | |||
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.38844 | |||
}} | |||
==FRG1== | |||
* {{medline-title | |||
|title=Intergenerational response of steroidogenesis-related genes to maternal malnutrition. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789120 | |||
|full-text-url=https://sci-hub.do/10.1017/S2040174419000060 | |||
}} | |||
==PTPRD== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==ADRM1== | |||
* {{medline-title | |||
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498 | |||
}} | |||
==ESPL1== | |||
* {{medline-title | |||
|title=Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32574725 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461696 | |||
}} | |||
==PGK2== | |||
* {{medline-title | |||
|title=Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31472347 | |||
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2019.124650 | |||
}} | |||
==IL18== | |||
* {{medline-title | |||
|title=Aging and the Inflammasomes. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30536177 | |||
|full-text-url=https://sci-hub.do/10.1007/978-3-319-89390-7_13 | |||
}} | |||
==PDE5A== | |||
* {{medline-title | |||
|title=Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass. | |||
|date=23.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32513693 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321982 | |||
}} | |||
==SIX3== | |||
* {{medline-title | |||
|title=CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type. | |||
|date=30.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102368 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265269 | |||
}} | |||
==RAD51B== | |||
* {{medline-title | |||
|title=Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human [[RAD52]] gene in a cardiovascular cohort. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024686 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.10.003 | |||
}} | |||
==MLH3== | |||
* {{medline-title | |||
|title=Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes. | |||
|date=19.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942922 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679441 | |||
}} | |||
==KCNB1== | |||
* {{medline-title | |||
|title=Oxidation of [[KCNB1]] potassium channels in the murine brain during aging is associated with cognitive impairment. | |||
|date=14.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922570 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471606 | |||
}} | |||
==AHCY== | |||
* {{medline-title | |||
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004 | |||
}} | |||
==WDR73== | |||
* {{medline-title | |||
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. | |||
|date=11.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604 | |||
}} | |||
==INHBE== | |||
* {{medline-title | |||
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature. | |||
|date=18.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778 | |||
}} | |||
==FOXN1== | |||
* {{medline-title | |||
|title=Thymic rejuvenation via [[FOXN1]]-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation. | |||
|date=17.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32790650 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526556 | |||
}} | |||
==TRIP13== | |||
* {{medline-title | |||
|title=BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome. | |||
|date=02.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31738183 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934189 | |||
}} | |||
==IL17RA== | |||
* {{medline-title | |||
|title=Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039977 | |||
|full-text-url=https://sci-hub.do/10.1080/07420528.2017.1361436 | |||
}} | |||
==MRPS5== | |||
* {{medline-title | |||
|title=Mutant [[MRPS5]] affects mitoribosomal accuracy and confers stress-related behavioral alterations. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30237157 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216279 | |||
}} | |||
==TEF== | |||
* {{medline-title | |||
|title=Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32189112 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09869-9 | |||
}} | |||
==HPD== | |||
* {{medline-title | |||
|title=Protein-Amino Acid Metabolism Disarrangements: The Hidden Enemy of Chronic Age-Related Conditions. | |||
|date=22.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29565819 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946176 | |||
}} | |||
==RXRA== | |||
* {{medline-title | |||
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923 | |||
}} | |||
==RPS19BP1== | |||
* {{medline-title | |||
|title=Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659678 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2020.153275 | |||
}} | |||
==UQCRC2== | |||
* {{medline-title | |||
|title=Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10). | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477336 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.025 | |||
}} | |||
==ITK== | |||
* {{medline-title | |||
|title=Does Tetralogy of Fallot affect brain aging? A proof-of-concept study. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130369 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103512 | |||
}} | |||
==NSF== | |||
* {{medline-title | |||
|title=Effects of air pollution on children from a socioecological perspective. | |||
|date=15.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31727016 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857293 | |||
}} | |||
==COL12A1== | |||
* {{medline-title | |||
|title=Genetic associations with age of menopause in familial longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937 | |||
}} | |||
==SELENOT== | |||
* {{medline-title | |||
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511 | |||
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9 | |||
}} | |||
==FA2H== | |||
* {{medline-title | |||
|title=C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30184537 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428043 | |||
}} | |||
==RACK1== | |||
* {{medline-title | |||
|title=Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging. | |||
|date=05.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31636180 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842600 | |||
}} | |||
==FAHD1== | |||
* {{medline-title | |||
|title=Oxaloacetate decarboxylase [[FAH]]D1 - a new regulator of mitochondrial function and senescence. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055189 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.07.007 | |||
}} | |||
==MST1== | |||
* {{medline-title | |||
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. | |||
|date=25.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331 | |||
}} | |||
==NTHL1== | |||
* {{medline-title | |||
|title=Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970600 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205949 | |||
}} | |||
==KCNQ4== | |||
* {{medline-title | |||
|title=Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32327991 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160671 | |||
}} | |||
==ITGB4== | |||
* {{medline-title | |||
|title=[[ITGB4]] deficiency induces senescence of airway epithelial cells through p53 activation. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30636108 | |||
|full-text-url=https://sci-hub.do/10.1111/febs.14749 | |||
}} | |||
==MRTFA== | |||
* {{medline-title | |||
|title=Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse. | |||
|date=01.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30422822 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355303 | |||
}} | |||
==KLF6== | |||
* {{medline-title | |||
|title=Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31824948 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882731 | |||
}} | |||
==FABP1== | |||
* {{medline-title | |||
|title=Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken. | |||
|date=01.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065718 | |||
|full-text-url=https://sci-hub.do/10.3382/ps/pez249 | |||
}} | |||
==CHIA== | |||
* {{medline-title | |||
|title=Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets. | |||
|date=26.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30486328 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316572 | |||
}} | |||
==SGSH== | |||
* {{medline-title | |||
|title=MPS-IIIA mice acquire autistic behaviours with age. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520737 | |||
|full-text-url=https://sci-hub.do/10.1007/s10545-018-0160-9 | |||
}} | |||
==MX1== | |||
* {{medline-title | |||
|title=Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection. | |||
|date=10.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878083 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230210 | |||
}} | |||
==BCAS1== | |||
* {{medline-title | |||
|title=Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs). | |||
|date=13.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760648 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382415 | |||
}} | |||
==KCNQ2== | |||
* {{medline-title | |||
|title=Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for [[GNG4]] and [[KCNQ2]] Genes. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338302 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098 | |||
}} | |||
==CPT1A== | |||
* {{medline-title | |||
|title=Alteration of fatty acid oxidation by increased [[CPT1A]] on replicative senescence of placenta-derived mesenchymal stem cells. | |||
|date=03.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31900237 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941254 | |||
}} | |||
==ADNP2== | |||
* {{medline-title | |||
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513 | |||
}} | |||
==SMARCD1== | |||
* {{medline-title | |||
|title=Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30155609 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269360 | |||
}} | |||
==ARNTL2== | |||
* {{medline-title | |||
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. | |||
|date=21.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686 | |||
}} | |||
==SYP== | |||
* {{medline-title | |||
|title=The neuropeptide-12 improves recognition memory and neuronal plasticity of the limbic system in old rats. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29740871 | |||
|full-text-url=https://sci-hub.do/10.1002/syn.22036 | |||
}} | |||
==AXL== | |||
* {{medline-title | |||
|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445 | |||
|full-text-url=https://sci-hub.do/10.1111/pcmr.12811 | |||
}} | |||
==MSH3== | |||
* {{medline-title | |||
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. | |||
|date=25.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.28417 | |||
}} | |||
==HAP1== | |||
* {{medline-title | |||
|title=The longevity SNP rs2802292 uncovered: [[HSF1]] activates stress-dependent expression of [[FOXO3]] through an intronic enhancer. | |||
|date=20.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733381 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009585 | |||
}} | |||
==EML6== | |||
* {{medline-title | |||
|title=Cell fate regulation by reticulon-4 in human prostate cancers. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.27704 | |||
}} | |||
==NT5E== | |||
* {{medline-title | |||
|title=The [[NT5E]] gene variant strongly affects the degradation rate of inosine 5'-monophosphate under postmortem conditions in Japanese Black beef. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31401370 | |||
|full-text-url=https://sci-hub.do/10.1016/j.meatsci.2019.107893 | |||
}} | |||
==PDF== | |||
* {{medline-title | |||
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models. | |||
|date=28.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415 | |||
}} | |||
==PTK2B== | |||
* {{medline-title | |||
|title=Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297968 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354244 | |||
}} | |||
==OXR1== | |||
* {{medline-title | |||
|title=Oxidation resistance 1 is a novel senolytic target. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29766639 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052462 | |||
}} | |||
==GLI1== | |||
* {{medline-title | |||
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483 | |||
}} | |||
==SP7== | |||
* {{medline-title | |||
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.28223 | |||
}} | |||
==SFRP5== | |||
* {{medline-title | |||
|title=[[SFRP5]] serves a beneficial role in arterial aging by inhibiting the proliferation, migration and inflammation of smooth muscle cells. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30221661 | |||
|full-text-url=https://sci-hub.do/10.3892/mmr.2018.9467 | |||
}} | |||
==PPARGC1A== | |||
* {{medline-title | |||
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. | |||
|date=08.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209 | |||
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054 | |||
}} | |||
==HMGCS1== | |||
* {{medline-title | |||
|title=The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain. | |||
|date=15.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125687 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.08.003 | |||
}} | |||
==COQ6== | |||
* {{medline-title | |||
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. | |||
|date=18.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522 | |||
}} | |||
==IGHD== | |||
* {{medline-title | |||
|title=Growth Hormone Deficiency: Health and Longevity. | |||
|date=01.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576428 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416709 | |||
}} | |||
==TEP1== | |||
* {{medline-title | |||
|title=[Influence of Age on the Susceptibility of Anopheles stephensi to Plasmodium berghei Infection]. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30141604 | |||
}} | |||
==MAF== | |||
* {{medline-title | |||
|title=Biocatalytic Degradation Efficiency of Postconsumer Polyethylene Terephthalate Packaging Determined by Their Polymer Microstructures. | |||
|date=17.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31380212 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662049 | |||
}} | |||
==NDUFS8== | |||
* {{medline-title | |||
|title=Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity. | |||
|date=01.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32773682 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494633 | |||
}} | |||
==RPL36== | |||
* {{medline-title | |||
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 | |||
}} | |||
==CACNA1B== | |||
* {{medline-title | |||
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | |||
}} | |||
==CBX3== | |||
* {{medline-title | |||
|title=Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. | |||
|date=24.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32979540 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115659 | |||
}} | |||
==MEOX2== | |||
* {{medline-title | |||
|title=Reduced expression of microRNA-130a promotes endothelial cell senescence and age-dependent impairment of neovascularization. | |||
|date=26.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32457253 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346016 | |||
}} | |||
==CLEC3B== | |||
* {{medline-title | |||
|title=[[CLEC3B]] p.S106G Mutant in a Caucasian Population of Successful Neurological Aging. | |||
|date=16.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570938 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494029 | |||
}} | |||
==ECSIT== | |||
* {{medline-title | |||
|title=Longevity-related molecular pathways are subject to midlife "switch" in humans. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168962 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612641 | |||
}} | |||
==KRT15== | |||
* {{medline-title | |||
|title=Extracellular proteoglycan decorin maintains human hair follicle stem cells. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320452 | |||
|full-text-url=https://sci-hub.do/10.1111/1346-8138.14678 | |||
}} | |||
==SARM1== | |||
* {{medline-title | |||
|title=Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy. | |||
|date=03.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978465 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640801 | |||
}} | |||
==HLA-DPA1== | |||
* {{medline-title | |||
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488 | |||
}} | |||
==GSTT1== | |||
* {{medline-title | |||
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | |||
}} | |||
==IKBKB== | |||
* {{medline-title | |||
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 | |||
}} | |||
==MAPK13== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==E2F3== | |||
* {{medline-title | |||
|title=Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730547 | |||
|full-text-url=https://sci-hub.do/10.1016/j.molimm.2018.04.010 | |||
}} | |||
==PAX5== | |||
* {{medline-title | |||
|title=Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low [[PAX5]]. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29425852 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clim.2018.02.003 | |||
}} | |||
==BHLHE40== | |||
* {{medline-title | |||
|title=Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1. | |||
|date=07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32360904 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105689 | |||
}} | |||
==TLR3== | |||
* {{medline-title | |||
|title=Repetitive [[TLR3]] activation in the lung induces skeletal muscle adaptations and cachexia. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452288 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911410 | |||
}} | |||
==PPFIA1== | |||
* {{medline-title | |||
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019 | |||
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6 | |||
}} | |||
==RBP1== | |||
* {{medline-title | |||
|title=The SR proteins SF2 and [[RBP1]] regulate triglyceride storage in the fat body of Drosophila. | |||
|date=27.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277943 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.151 | |||
}} | |||
==FGFR2== | |||
* {{medline-title | |||
|title=Oncogenic mutations in histologically normal endometrium: the new normal? | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483 | |||
|full-text-url=https://sci-hub.do/10.1002/path.5314 | |||
}} | |||
==SUCNR1== | |||
* {{medline-title | |||
|title=[The effect of Mexidol on cerebral mitochondriogenesis at a young age and during aging]. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105271 | |||
|full-text-url=https://sci-hub.do/10.17116/jnevro202012001162 | |||
}} | |||
==MMP12== | |||
* {{medline-title | |||
|title=Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for [[MMP12]] through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice. | |||
|date=01.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814604 | |||
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1601696 | |||
}} | |||
==STN1== | |||
* {{medline-title | |||
|title=[[CTC1]]-[[STN1]] coordinates G- and C-strand synthesis to regulate telomere length. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774655 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479 | |||
}} | |||
==NEO1== | |||
* {{medline-title | |||
|title=Neogenin-1 distinguishes between myeloid-biased and balanced [i]Hoxb5[/i] mouse long-term hematopoietic stem cells. | |||
|date=10.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754028 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911217 | |||
}} | |||
==CNTF== | |||
* {{medline-title | |||
|title=Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha. | |||
|date=01.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30861131 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656591 | |||
}} | |||
==DYNC2H1== | |||
* {{medline-title | |||
|title=Role for intraflagellar transport in building a functional transition zone. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429209 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280794 | |||
}} | |||
==PHGDH== | |||
* {{medline-title | |||
|title=Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase. | |||
|date=01.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31108107 | |||
|full-text-url=https://sci-hub.do/10.1016/j.taap.2019.05.014 | |||
}} | |||
==HSPB6== | |||
* {{medline-title | |||
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 | |||
}} | |||
==DTNBP1== | |||
* {{medline-title | |||
|title=Genetic Biomarkers on Age-Related Cognitive Decline. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307 | |||
}} | |||
==ATG16L1== | |||
* {{medline-title | |||
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875 | |||
}} | |||
==TAAR1== | |||
* {{medline-title | |||
|title=Minimal Age-Related Alterations in Behavioral and Hematological Parameters in Trace Amine-Associated Receptor 1 ([[TAAR1]]) Knockout Mice. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31399838 | |||
|full-text-url=https://sci-hub.do/10.1007/s10571-019-00721-4 | |||
}} | |||
==MAFB== | |||
* {{medline-title | |||
|title=Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy. | |||
|date=01.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30605403 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485685 | |||
}} | |||
==LRRK1== | |||
* {{medline-title | |||
|title=Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29056298 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693787 | |||
}} | |||
==TECPR2== | |||
* {{medline-title | |||
|title=Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging. | |||
|date=01-03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30681437 | |||
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000294 | |||
}} | |||
==CCDC88A== | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
==NPAS2== | |||
* {{medline-title | |||
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. | |||
|date=21.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686 | |||
}} | |||
==MAF1== | |||
* {{medline-title | |||
|title=Beyond regulation of pol III: Role of [[MAF1]] in growth, metabolism, aging and cancer. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407795 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbagrm.2018.01.019 | |||
}} | |||
==MBD2== | |||
* {{medline-title | |||
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493 | |||
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y | |||
}} | |||
==BRD2== | |||
* {{medline-title | |||
|title=Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32559200 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304595 | |||
}} | |||
==SIK3== | |||
* {{medline-title | |||
|title=Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids. | |||
|date=25.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566214 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518561 | |||
}} | |||
==SLC52A3== | |||
* {{medline-title | |||
|title=Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. | |||
|date=01.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053833 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808726 | |||
}} | |||
==MAP1B== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
==MGRN1== | |||
* {{medline-title | |||
|title=Chronic and age-dependent effects of the spongiform neurodegeneration-associated [[MGRN1]] E3 ubiquitin ligase on mitochondrial homeostasis. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089807 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639055 | |||
}} | |||
==PTCH1== | |||
* {{medline-title | |||
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483 | |||
}} | |||
==GZMK== | |||
* {{medline-title | |||
|title=Comprehensive Profiling of an Aging Immune System Reveals Clonal [[GZMK]] CD8 T Cells as Conserved Hallmark of Inflammaging. | |||
|date=21.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33271118 | |||
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2020.11.005 | |||
}} | |||
==HADHA== | |||
* {{medline-title | |||
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223 | |||
}} | |||
==KDM2A== | |||
* {{medline-title | |||
|title=SIRT6 mono-ADP ribosylates [[KDM2A]] to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. | |||
|date=25.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32584788 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343504 | |||
}} | |||
==LIN28B== | |||
* {{medline-title | |||
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184 | |||
}} | |||
==SUZ12== | |||
* {{medline-title | |||
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. | |||
|date=05.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005 | |||
}} | |||
==HIF1A== | |||
* {{medline-title | |||
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220 | |||
}} | |||
==DGAT1== | |||
* {{medline-title | |||
|title=Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPα-p300/[[DGAT1]] pathway. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024407 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771394 | |||
}} | |||
==WNT5A== | |||
* {{medline-title | |||
|title=[[WNT5A]] supports viability of senescent human dental follicle cells. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30406314 | |||
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3467-9 | |||
}} | |||
==HLA-E== | |||
* {{medline-title | |||
|title=Senescent cells evade immune clearance via [[HLA-E]]-mediated NK and CD8 T cell inhibition. | |||
|date=03.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160572 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547655 | |||
}} | |||
==ELL== | |||
* {{medline-title | |||
|title=Exceptional Longevity and Polygenic Risk for Cardiovascular Health. | |||
|date=18.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30889929 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471529 | |||
}} | |||
==SUN1== | |||
* {{medline-title | |||
|title=Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging. | |||
|date=26.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808750 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397528 | |||
}} | |||
==JUNB== | |||
* {{medline-title | |||
|title=Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of [[JUNB]]. | |||
|date=19.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31806366 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.11.145 | |||
}} | |||
==NTN4== | |||
* {{medline-title | |||
|title=[[EGF]]/[[EGF]]R upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence. | |||
|date=04.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514230 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426 | |||
}} | |||
==C2CD2== | |||
* {{medline-title | |||
|title=Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort. | |||
|date=20.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29158487 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696534 | |||
}} | |||
==WNT7A== | |||
* {{medline-title | |||
|title=Exogenous Expression of [[WNT7A]] in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436833 | |||
|full-text-url=https://sci-hub.do/10.2174/1871520620666200521114100 | |||
}} | |||
==DLC1== | |||
* {{medline-title | |||
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells. | |||
|date=15.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031 | |||
}} | |||
==CETP== | |||
* {{medline-title | |||
|title=Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30159092 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080062 | |||
}} | |||
==GIT1== | |||
* {{medline-title | |||
|title=[[GIT2]]-A keystone in ageing and age-related disease. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002 | |||
}} | |||
==UPF1== | |||
* {{medline-title | |||
|title=Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity. | |||
|date=21.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28824175 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563511 | |||
}} | |||
==SH2B3== | |||
* {{medline-title | |||
|title=Genome-wide meta-analysis associates HLA-DQA1/DRB1 and [[LPA]] and lifestyle factors with human longevity. | |||
|date=13.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29030599 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715013 | |||
}} | |||
==DEPDC5== | |||
* {{medline-title | |||
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9 | |||
}} | |||
==CASS4== | |||
* {{medline-title | |||
|title=Genetic Biomarkers on Age-Related Cognitive Decline. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307 | |||
}} | |||
==ZNF396== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==MUC5AC== | |||
* {{medline-title | |||
|title=InflammAging at Ocular Surface: Clinical and Biomolecular Analyses in Healthy Volunteers. | |||
|date=01.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31022299 | |||
|full-text-url=https://sci-hub.do/10.1167/iovs.18-25822 | |||
}} | |||
==TNPO3== | |||
* {{medline-title | |||
|title=Genetic associations with age of menopause in familial longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937 | |||
}} | |||
==GCK== | |||
* {{medline-title | |||
|title=The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31558549 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868460 | |||
}} | |||
==ZFHX3== | |||
* {{medline-title | |||
|title=Shift work, DNA methylation and epigenetic age. | |||
|date=01.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30879037 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857743 | |||
}} | |||
==NCK2== | |||
* {{medline-title | |||
|title=Genetic associations with age of menopause in familial longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937 | |||
}} | |||
==TGFBR2== | |||
* {{medline-title | |||
|title=TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis. | |||
|date=08.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31068441 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102613 | |||
}} | |||
==ALDOA== | |||
* {{medline-title | |||
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2 | |||
}} | |||
==SLC24A5== | |||
* {{medline-title | |||
|title=[A question of colour]. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29384103 | |||
|full-text-url=https://sci-hub.do/10.1051/medsci/20183401020 | |||
}} | |||
==HSPA5== | |||
* {{medline-title | |||
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009 | |||
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6 | |||
}} | |||
==SKAP2== | |||
* {{medline-title | |||
|title=Longevity-related molecular pathways are subject to midlife "switch" in humans. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168962 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612641 | |||
}} | |||
==UACA== | |||
* {{medline-title | |||
|title=Knockdown of [i][[UACA]][/i] inhibitsproliferation and invasion and promotes senescence of hepatocellular carcinoma cells. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31949867 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962967 | |||
}} | |||
==UBE4B== | |||
* {{medline-title | |||
|title=CircRNAs in the tree shrew ([i]Tupaia belangeri[/i]) brain during postnatal development and aging. | |||
|date=30.04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29723158 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940110 | |||
}} | |||
==CUL3== | |||
* {{medline-title | |||
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9 | |||
}} | |||
==SFPQ== | |||
* {{medline-title | |||
|title=Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis. | |||
|date=08.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32267831 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185106 | |||
}} | |||
==PEX5== | |||
* {{medline-title | |||
|title=Aging lowers [[PEX5]] levels in cortical neurons in male and female mouse brains. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32777345 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484460 | |||
}} | |||
==RELA== | |||
* {{medline-title | |||
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157 | |||
|full-text-url=https://sci-hub.do/10.1111/jbg.12299 | |||
}} | |||
==THBS4== | |||
* {{medline-title | |||
|title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment. | |||
|date=18.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664 | |||
}} | |||
==TTL== | |||
* {{medline-title | |||
|title=Longitudinal Associations of Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio with Biomarkers of Oxidative Stress in Older Adults: Results of a Large Cohort Study. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31986512 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098284 | |||
}} | |||
==AKT2== | |||
* {{medline-title | |||
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 | |||
}} | |||
==SCN2B== | |||
* {{medline-title | |||
|title=MicroRNA‑449a regulates the progression of brain aging by targeting [[SCN2B]] in SAMP8 mice. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32124967 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053848 | |||
}} | |||
==TRAF2== | |||
* {{medline-title | |||
|title=The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31042012 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711781 | |||
}} | |||
==STK32C== | |||
* {{medline-title | |||
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | |||
|date=25.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | |||
}} | |||
==RAF1== | |||
* {{medline-title | |||
|title=Circular [i]ANRIL[/i] isoforms switch from repressors to activators of [i]p15/CDKN2B[/i] expression during [[RAF1]] oncogene-induced senescence. | |||
|date=29.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32862732 | |||
|full-text-url=https://sci-hub.do/10.1080/15476286.2020.1812910 | |||
}} | |||
==VPS29== | |||
* {{medline-title | |||
|title=Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development. | |||
|date=16.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654520 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359594 | |||
}} | |||
==TPRKB== | |||
* {{medline-title | |||
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. | |||
|date=11.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604 | |||
}} | |||
==DPYSL2== | |||
* {{medline-title | |||
|title=Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31733664 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939615 | |||
}} | |||
==EIF2B2== | |||
* {{medline-title | |||
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 | |||
}} | |||
==ELOVL6== | |||
* {{medline-title | |||
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2 | |||
}} | |||
==G6PC3== | |||
* {{medline-title | |||
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death | |||
|date=13.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814 | |||
}} | |||
==RPL30== | |||
* {{medline-title | |||
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261 | |||
}} | |||
==AKAP12== | |||
* {{medline-title | |||
|title=A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29314444 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918158 | |||
}} | |||
==CD72== | |||
* {{medline-title | |||
|title=Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930899 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428705 | |||
}} | |||
==RPL31== | |||
* {{medline-title | |||
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261 | |||
}} | |||
==PEX19== | |||
* {{medline-title | |||
|title=A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31854076 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996960 | |||
}} | |||
==TRAV1-2== | |||
* {{medline-title | |||
|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826 | |||
}} | |||
==CAP2== | |||
* {{medline-title | |||
|title=Targeting MRTF/[[SRF]] in [[CAP2]]-dependent dilated cardiomyopathy delays disease onset. | |||
|date=21.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30762586 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483011 | |||
}} | |||
==MDK== | |||
* {{medline-title | |||
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. | |||
|date=20.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988 | |||
}} | |||
==AKTIP== | |||
* {{medline-title | |||
|title=Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29635765 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052474 | |||
}} | |||
==SPRTN== | |||
* {{medline-title | |||
|title=Tandem Deubiquitination and Acetylation of [[SPRTN]] Promotes DNA-Protein Crosslink Repair and Protects against Aging. | |||
|date=03.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32649882 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484104 | |||
}} | |||
==SENP1== | |||
* {{medline-title | |||
|title=Aging-related SUMOylation pattern in the cortex and blood plasma of wild type mice. | |||
|date=06.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325714 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.01.004 | |||
}} | |||
==IL1R2== | |||
* {{medline-title | |||
|title=Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28777886 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721243 | |||
}} | |||
==CXCR6== | |||
* {{medline-title | |||
|title=[[CXCR6]] Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and [[CD4]] T-Cell-Dependent Control of Senescence. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710528 | |||
|full-text-url=https://sci-hub.do/10.1053/j.gastro.2019.01.247 | |||
}} | |||
==CD48== | |||
* {{medline-title | |||
|title=Genetic overexpression of [[COMP]]-Ang1 impairs BM microenvironment and induces senescence of BM HSCs. | |||
|date=15.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604278 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.210 | |||
}} | |||
==GATA1== | |||
* {{medline-title | |||
|title=Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31299382 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708771 | |||
}} | |||
==MPHOSPH6== | |||
* {{medline-title | |||
|title=Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. | |||
|date=05.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109421 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058826 | |||
}} | |||
==CXCL17== | |||
* {{medline-title | |||
|title=[Age-related aspects of the involvement of heat shock proteins in the pathogenesis of osteoarthritis]. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849876 | |||
}} | |||
==ATF3== | |||
* {{medline-title | |||
|title=[[ATF3]] represses [[PINK1]] gene transcription in lung epithelial cells to control mitochondrial homeostasis. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29363258 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866 | |||
}} | |||
==NRL== | |||
* {{medline-title | |||
|title=Development of a cyclophosphamide stress test to predict resilience to aging in mice. | |||
|date=12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32613492 | |||
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00222-z | |||
}} | |||
==SCO1== | |||
* {{medline-title | |||
|title=Real-Time PCR Analysis of Metabolism-Related Genes in a Long-Lived Model of C. elegans. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32219749 | |||
|full-text-url=https://sci-hub.do/10.1007/978-1-0716-0471-7_12 | |||
}} | |||
==KLF1== | |||
* {{medline-title | |||
|title=Mutant [[KLF1]] in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis. | |||
|date=24.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30143664 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109071 | |||
}} | |||
==MYCN== | |||
* {{medline-title | |||
|title=Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947931 | |||
}} | |||
==ARL13B== | |||
* {{medline-title | |||
|title=[[ARL13B]], a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments. | |||
|date=20.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573647 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381253 | |||
}} | |||
==CPNE1== | |||
* {{medline-title | |||
|title=Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence. | |||
|date=04.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274830 | |||
|full-text-url=https://sci-hub.do/10.1111/acel.13276 | |||
}} | |||
==PLN== | |||
* {{medline-title | |||
|title=An analysis of the costs of treating aged patients in a large clinical hospital in Poland under the pressure of recent demographic trends. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399116 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212232 | |||
}} | |||
==POLG2== | |||
* {{medline-title | |||
|title=An N-Ethyl-N-Nitrosourea (ENU)-Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30395686 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446808 | |||
}} | |||
==REV1== | |||
* {{medline-title | |||
|title=[[REV1]] inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. | |||
|date=17.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168727 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682577 | |||
}} | |||
==AIDA== | |||
* {{medline-title | |||
|title=Identification of Postharvest Senescence Regulators Through Map-Based Cloning Using Detached Arabidopsis Inflorescences as a Model Tissue. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392668 | |||
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-7672-0_17 | |||
}} | |||
==CRBN== | |||
* {{medline-title | |||
|title=Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity. | |||
|date=24.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32332723 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181703 | |||
}} | |||
==LRRC8B== | |||
* {{medline-title | |||
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | |||
|date=25.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | |||
}} | |||
==SHANK3== | |||
* {{medline-title | |||
|title=Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background. | |||
|date=10.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30305163 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180595 | |||
}} | |||
==SPATS2L== | |||
* {{medline-title | |||
|title=Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585438 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818258 | |||
}} | |||
==TAS1R2== | |||
* {{medline-title | |||
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. | |||
|date=18.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100 | |||
}} | |||
==CYP2C9== | |||
* {{medline-title | |||
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442 | |||
}} | |||
==TCTA== | |||
* {{medline-title | |||
|title=Exciplex-Forming Cohost for High Efficiency and High Stability Phosphorescent Organic Light-Emitting Diodes. | |||
|date=17.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29265796 | |||
|full-text-url=https://sci-hub.do/10.1021/acsami.7b15034 | |||
}} | |||
==DRAM2== | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
==PCCB== | |||
* {{medline-title | |||
|title=Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29159707 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832583 | |||
}} | |||
==SCN2A== | |||
* {{medline-title | |||
|title=Na 1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age. | |||
|date=09.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31501495 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733925 | |||
}} | |||
==ARNTL== | |||
* {{medline-title | |||
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. | |||
|date=21.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686 | |||
}} | |||
==CR2== | |||
* {{medline-title | |||
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. | |||
|date=19.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985 | |||
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052 | |||
}} | |||
==CYP24A1== | |||
* {{medline-title | |||
|title=Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism. | |||
|date=22.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823 | |||
}} | |||
==HAX1== | |||
* {{medline-title | |||
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death | |||
|date=13.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814 | |||
}} | |||
==NPBWR1== | |||
* {{medline-title | |||
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157 | |||
|full-text-url=https://sci-hub.do/10.1111/jbg.12299 | |||
}} | |||
==FKBP5== | |||
* {{medline-title | |||
|title=Epigenetic upregulation of [[FKBP5]] by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk. | |||
|date=04.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113877 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561294 | |||
}} | |||
==GREM2== | |||
* {{medline-title | |||
|title=Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31709279 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831850 | |||
}} | |||
==GSTA1== | |||
* {{medline-title | |||
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | |||
}} | |||
==TNNI1== | |||
* {{medline-title | |||
|title=Regular aerobic exercise-ameliorated troponin I carbonylation to mitigate aged rat soleus muscle functional recession. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820991 | |||
|full-text-url=https://sci-hub.do/10.1113/EP087564 | |||
}} | |||
==SMOX== | |||
* {{medline-title | |||
|title=Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine. | |||
|date=14.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29443878 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872171 | |||
}} | |||
==GRK6== | |||
* {{medline-title | |||
|title=Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304635 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801044 | |||
}} | |||
==PRM1== | |||
* {{medline-title | |||
|title=Cytological and molecular aspects of the ageing sperm. | |||
|date=01.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142 | |||
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357 | |||
}} | |||
==MAX== | |||
* {{medline-title | |||
|title=Validation of the MedUseQ: A Self-Administered Screener for Older Adults to Assess Medication Use Problems. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656678 | |||
|full-text-url=https://sci-hub.do/10.1177/0897190018766789 | |||
}} | |||
==LHCGR== | |||
* {{medline-title | |||
|title=Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats. | |||
|date=11.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050653 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590010 | |||
}} | |||
==LCN2== | |||
* {{medline-title | |||
|title=Anthropometric and glucometabolic changes in an aged mouse model of lipocalin-2 overexpression. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082752 | |||
|full-text-url=https://sci-hub.do/10.1038/s41366-018-0171-5 | |||
}} | |||
==ICAM1== | |||
* {{medline-title | |||
|title=An Inhibitor of Activated Blood Coagulation Factor X Shows Anti-Endothelial Senescence and Anti-Atherosclerotic Effects. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31266015 | |||
|full-text-url=https://sci-hub.do/10.1159/000499975 | |||
}} | |||
==DPP6== | |||
* {{medline-title | |||
|title=A novel structure associated with aging is augmented in the [[DPP6]]-KO mouse brain. | |||
|date=23.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33225987 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682109 | |||
}} | |||
==PFKFB3== | |||
* {{medline-title | |||
|title=DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101015 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871568 | |||
}} | |||
==GPR37== | |||
* {{medline-title | |||
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342 | |||
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9 | |||
}} | |||
==HYOU1== | |||
* {{medline-title | |||
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009 | |||
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6 | |||
}} | |||
==GUK1== | |||
* {{medline-title | |||
|title=Characterization of the impact of GMP/GDP synthesis inhibition on replicative lifespan extension in yeast. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32232569 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367712 | |||
}} | |||
==AQP4== | |||
* {{medline-title | |||
|title=Overexpression of Slit2 improves function of the paravascular pathway in the aging mouse brain. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30085336 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108881 | |||
}} | |||
==ELANE== | |||
* {{medline-title | |||
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death | |||
|date=13.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814 | |||
}} | |||
==SLC16A7== | |||
* {{medline-title | |||
|title=Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach. | |||
|date=23.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33095951 | |||
|full-text-url=https://sci-hub.do/10.1111/jdv.17014 | |||
}} | |||
==CD2== | |||
* {{medline-title | |||
|title=Adaptive NKG2C CD57 Natural Killer Cell and Tim-3 Expression During Viral Infections. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731749 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919961 | |||
}} | |||
==ERCC8== | |||
* {{medline-title | |||
|title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141 | |||
}} | |||
==MFSD2A== | |||
* {{medline-title | |||
|title=Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease. | |||
|date=20.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31861865 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981746 | |||
}} | |||
==SDC2== | |||
* {{medline-title | |||
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. | |||
|date=01.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677 | |||
}} | |||
==ACD== | |||
* {{medline-title | |||
|title=Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging. | |||
|date=02.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792241 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889148 | |||
}} | |||
==NRARP== | |||
* {{medline-title | |||
|title=Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing [[NRARP]]. | |||
|date=10.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30274778 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.09.045 | |||
}} | |||
==CTNS== | |||
* {{medline-title | |||
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869 | |||
}} | |||
==TYK2== | |||
* {{medline-title | |||
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006 | |||
}} | |||
==GPR158== | |||
* {{medline-title | |||
|title=RbAp48 Protein Is a Critical Component of [[GPR158]]/OCN Signaling and Ameliorates Age-Related Memory Loss. | |||
|date=23.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355501 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725275 | |||
}} | |||
==NPC2== | |||
* {{medline-title | |||
|title=Attenuation of the Niemann-Pick type [[C2]] disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29655638 | |||
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2018.04.001 | |||
}} | |||
==RAI1== | |||
* {{medline-title | |||
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | |||
|date=25.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | |||
}} | |||
==TSHB== | |||
* {{medline-title | |||
|title=Adipose [[TSHB]] in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448824 | |||
|full-text-url=https://sci-hub.do/10.1159/000495170 | |||
}} | |||
==ABCG5== | |||
* {{medline-title | |||
|title=2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. | |||
|date=01.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30939745 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479705 | |||
}} | |||
==SOS1== | |||
* {{medline-title | |||
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice. | |||
|date=21.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397 | |||
}} | |||
==SLC30A1== | |||
* {{medline-title | |||
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. | |||
|date=01.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006 | |||
}} | |||
==NDUFS1== | |||
* {{medline-title | |||
|title=Mapping the protein phosphorylation sites in human mitochondrial complex I (NADH: Ubiquinone oxidoreductase): A bioinformatics study with implications for brain aging and neurodegeneration. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29499254 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2018.02.004 | |||
}} | |||
==SELENOV== | |||
* {{medline-title | |||
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511 | |||
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9 | |||
}} | |||
==PRMT1== | |||
* {{medline-title | |||
|title=Reactive oxygen species extend insect life span using components of the insulin-signaling pathway. | |||
|date=12.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847950 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604040 | |||
}} | |||
==HAS2== | |||
* {{medline-title | |||
|title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508 | |||
|full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7 | |||
}} | |||
==KDM2B== | |||
* {{medline-title | |||
|title=Identification of Structural Elements of the Lysine Specific Demethylase 2B CxxC Domain Associated with Replicative Senescence Bypass in Primary Mouse Cells. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270414 | |||
|full-text-url=https://sci-hub.do/10.1007/s10930-020-09895-z | |||
}} | |||
==ITGB1== | |||
* {{medline-title | |||
|title=Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29599141 | |||
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.117.310685 | |||
}} | |||
==EFEMP1== | |||
* {{medline-title | |||
|title=A novel age-related venous amyloidosis derived from [[EGF]]-containing fibulin-like extracellular matrix protein 1. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30565683 | |||
|full-text-url=https://sci-hub.do/10.1002/path.5203 | |||
}} | |||
==S100A12== | |||
* {{medline-title | |||
|title=Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model. | |||
|date=06.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991479 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078409 | |||
}} | |||
==ATG10== | |||
* {{medline-title | |||
|title=Genetic associations with age of menopause in familial longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937 | |||
}} | |||
==PSMG1== | |||
* {{medline-title | |||
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551 | |||
}} | |||
==NDRG1== | |||
* {{medline-title | |||
|title=Cx43 phosphorylation-mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein [[NDRG1]]. | |||
|date=02.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189653 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682735 | |||
}} | |||
==AP2B1== | |||
* {{medline-title | |||
|title=Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice. | |||
|date=20.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31860870 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949063 | |||
}} | |||
==UGT2B28== | |||
* {{medline-title | |||
|title=Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a [[UGT2B28]] genomic variation. | |||
|date=05.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31805979 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896495 | |||
}} | |||
==PTGS2== | |||
* {{medline-title | |||
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. | |||
|date=21.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237 | |||
}} | |||
==MCM5== | |||
* {{medline-title | |||
|title=Changes in [[MCM2]]-7 proteins at senescence. | |||
|date=27.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751 | |||
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062 | |||
}} | |||
==LAMA2== | |||
* {{medline-title | |||
|title=[Alu insertion-deletion polymorphism of [[COL13A1]] and [[LAMA2]] genes: The analysis of association with longevity]. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369589 | |||
}} | |||
==ACVR1== | |||
* {{medline-title | |||
|title=Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31998237 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966325 | |||
}} | |||
==VASP== | |||
* {{medline-title | |||
|title=Reversal of Aging-Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein-Protein Interfaces. | |||
|date=18.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021807 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201469 | |||
}} | |||
==PPM1A== | |||
* {{medline-title | |||
|title=The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1. | |||
|date=03.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31382626 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723262 | |||
}} | |||
==RNF13== | |||
* {{medline-title | |||
|title=The effects of environmental stressors on candidate aging associated genes. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32344118 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110952 | |||
}} | |||
==VSIG4== | |||
* {{medline-title | |||
|title=Immune checkpoint protein [[VSIG4]] as a biomarker of aging in murine adipose tissue. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856419 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576241 | |||
}} | |||
==AMHR2== | |||
* {{medline-title | |||
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551 | |||
}} | |||
==ATP6V1E1== | |||
* {{medline-title | |||
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205 | |||
}} | |||
==TGDS== | |||
* {{medline-title | |||
|title=The evaluation and design of a short depression screening tool in Turkish older adults. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29560848 | |||
|full-text-url=https://sci-hub.do/10.1017/S1041610218000236 | |||
}} | |||
==CDKN1C== | |||
* {{medline-title | |||
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature. | |||
|date=18.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778 | |||
}} | |||
==CXCL14== | |||
* {{medline-title | |||
|title=Identification of genes associated with endometrial cell aging. | |||
|date=01.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33258951 | |||
|full-text-url=https://sci-hub.do/10.1093/molehr/gaaa078 | |||
}} | |||
==EWSR1== | |||
* {{medline-title | |||
|title=[[EWSR1]], a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways. | |||
|date=01.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30481590 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527469 | |||
}} | |||
==RNF10== | |||
* {{medline-title | |||
|title=Reduced RING finger protein 10 expression in macrophages is associated with aging-related inflammation. | |||
|date=28.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33249776 | |||
|full-text-url=https://sci-hub.do/10.1002/2211-5463.13049 | |||
}} | |||
==SMO== | |||
* {{medline-title | |||
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483 | |||
}} | |||
==ERCC2== | |||
* {{medline-title | |||
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073 | |||
}} | |||
==NDRG2== | |||
* {{medline-title | |||
|title=[[NDRG2]] Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain. | |||
|date=04.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31947996 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982267 | |||
}} | |||
==AMFR== | |||
* {{medline-title | |||
|title=Mice heterozygous for the Cdh23/Ahl1 mutation show age-related deficits in auditory temporal processing. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247458 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732241 | |||
}} | |||
==DES== | |||
* {{medline-title | |||
|title=Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis. | |||
|date=20.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29558926 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859529 | |||
}} | |||
==UBB== | |||
* {{medline-title | |||
|title=Different Expression Levels of Human Mutant Ubiquitin B ([[UBB]] ) Can Modify Chronological Lifespan or Stress Resistance of [i]Saccharomyces cerevisiae[/i]. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29950972 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008557 | |||
}} | |||
==RAD23A== | |||
* {{medline-title | |||
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 | |||
}} | |||
==TSG101== | |||
* {{medline-title | |||
|title=Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging. | |||
|date=01.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220525 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116582 | |||
}} | |||
==HNRNPA1== | |||
* {{medline-title | |||
|title=[[HNRNPA1]]-mediated 3' UTR length changes of [i]HN1[/i] contributes to cancer- and senescence-associated phenotypes. | |||
|date=30.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257225 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660030 | |||
}} | |||
==ATP2B1== | |||
* {{medline-title | |||
|title=Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28795531 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595685 | |||
}} | |||
==ANG== | |||
* {{medline-title | |||
|title=Age-related differences in the cutaneous vascular response to exogenous angiotensin II. | |||
|date=01.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30499715 | |||
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00509.2018 | |||
}} | |||
==PTPN1== | |||
* {{medline-title | |||
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073 | |||
}} | |||
==GRB10== | |||
* {{medline-title | |||
|title=De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555819 | |||
|full-text-url=https://sci-hub.do/10.1530/JME-18-0018 | |||
}} | |||
==BAZ2B== | |||
* {{medline-title | |||
|title=Two conserved epigenetic regulators prevent healthy ageing. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32103178 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2037-y | |||
}} | |||
==REC8== | |||
* {{medline-title | |||
|title=Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667147 | |||
|full-text-url=https://sci-hub.do/10.1007/s11655-018-2835-3 | |||
}} | |||
==LRP6== | |||
* {{medline-title | |||
|title=Low-density lipoprotein receptor-related protein 6-mediated signaling pathways and associated cardiovascular diseases: diagnostic and therapeutic opportunities. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32076828 | |||
|full-text-url=https://sci-hub.do/10.1007/s00439-020-02124-8 | |||
}} | |||
==TRPV6== | |||
* {{medline-title | |||
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433 | |||
}} | |||
==VHLL== | |||
* {{medline-title | |||
|title=The Monetary Valuation of Lifetime Health Improvement and Life Expectancy Gains in Turkey. | |||
|date=29.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28961227 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664652 | |||
}} | |||
==POU5F1== | |||
* {{medline-title | |||
|title=Cell quality evaluation with gene expression analysis of spheroids (3D) and adherent (2D) adipose stem cells. | |||
|date=24.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33148459 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2020.145269 | |||
}} | |||
==HDAC10== | |||
* {{medline-title | |||
|title=Middle-aged female rats lack changes in histone H3 acetylation in the anterior hypothalamus observed in young females on the day of a luteinizing hormone surge. | |||
|date=17.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31434815 | |||
|full-text-url=https://sci-hub.do/10.5582/bst.2019.01162 | |||
}} | |||
==FDPS== | |||
* {{medline-title | |||
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922 | |||
}} | |||
==GDA== | |||
* {{medline-title | |||
|title=Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944897 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436911 | |||
}} | |||
==BOC== | |||
* {{medline-title | |||
|title=Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations. | |||
|date=01.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32140711 | |||
|full-text-url=https://sci-hub.do/10.1093/jn/nxaa031 | |||
}} | |||
==APLNR== | |||
* {{medline-title | |||
|title=Endothelial [[APLNR]] regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects. | |||
|date=13.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904225 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703224 | |||
}} | |||
==LEF1== | |||
* {{medline-title | |||
|title=LncRNA H19 targets miR-22 to modulate H O -induced deregulation in nucleus pulposus cell senescence, proliferation, and ECM synthesis through Wnt signaling. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520849 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.26738 | |||
}} | |||
==RHOB== | |||
* {{medline-title | |||
|title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes. | |||
|date=13.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600 | |||
}} | |||
==SNAI2== | |||
* {{medline-title | |||
|title=Reawakening of dormant estrogen-dependent human breast cancer cells by bone marrow stroma secretory senescence. | |||
|date=17.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119678 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098600 | |||
}} | |||
==UCP3== | |||
* {{medline-title | |||
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001 | |||
}} | |||
==APPL1== | |||
* {{medline-title | |||
|title=Insulin and adipokine signaling and their cross-regulation in postmortem human brain. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31539648 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960343 | |||
}} | |||
==DGCR8== | |||
* {{medline-title | |||
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif. | |||
|date=29.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004 | |||
}} | |||
==VCL== | |||
* {{medline-title | |||
|title=The effects of different preservation methods on ide (Leuciscus idus) sperm and the longevity of sperm movement. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397922 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cryobiol.2018.01.014 | |||
}} | |||
==CDH1== | |||
* {{medline-title | |||
|title=Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation. | |||
|date=15.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32010971 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496346 | |||
}} | |||
==GP1BA== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==SMC2== | |||
* {{medline-title | |||
|title=The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence. | |||
|date=10.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336977 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.065 | |||
}} | |||
==ACADM== | |||
* {{medline-title | |||
|title=High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888352 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jfma.2017.08.008 | |||
}} | |||
==SYT7== | |||
* {{medline-title | |||
|title=Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells. | |||
|date=28.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30647108 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367206 | |||
}} | |||
==ATG4D== | |||
* {{medline-title | |||
|title=Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats. | |||
|date=17.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242723 | |||
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b02567 | |||
}} | |||
==CREBBP== | |||
* {{medline-title | |||
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. | |||
|date=22.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318 | |||
}} | |||
==ADAMTS3== | |||
* {{medline-title | |||
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019 | |||
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6 | |||
}} | |||
==IGFBP4== | |||
* {{medline-title | |||
|title=Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey. | |||
|date=11.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31601169 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788010 | |||
}} | |||
==KY== | |||
* {{medline-title | |||
|title=Combination of acupuncture and Chinese herbal formula for elderly adults with mild cognitive impairment: protocol for a randomized controlled trial. | |||
|date=11.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30744676 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371495 | |||
}} | |||
==ANGPT2== | |||
* {{medline-title | |||
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging. | |||
|date=14.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506 | |||
}} | |||
==PF4V1== | |||
* {{medline-title | |||
|title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301 | |||
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x | |||
}} | |||
==WNK4== | |||
* {{medline-title | |||
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534 | |||
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4 | |||
}} | |||
==RRM1== | |||
* {{medline-title | |||
|title=α-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977294 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612645 | |||
}} | |||
==CINP== | |||
* {{medline-title | |||
|title=Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging. | |||
|date=01-03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30681437 | |||
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000294 | |||
}} | |||
==NPM1== | |||
* {{medline-title | |||
|title=Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats. | |||
|date=29.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31784606 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884578 | |||
}} | |||
==GRK4== | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 | |||
}} | |||
==PRMT8== | |||
* {{medline-title | |||
|title=Arginine Methyltransferase [[PRMT8]] Provides Cellular Stress Tolerance in Aging Motoneurons. | |||
|date=29.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054395 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113905 | |||
}} | |||
==FADS1== | |||
* {{medline-title | |||
|title=Aging and [[FADS1]] polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U- C]linoleic acid. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31492428 | |||
|full-text-url=https://sci-hub.do/10.1016/j.plefa.2019.07.003 | |||
}} | |||
==ATG4B== | |||
* {{medline-title | |||
|title=Impaired autophagic activity and [[ATG4B]] deficiency are associated with increased endoplasmic reticulum stress-induced lung injury. | |||
|date=27.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30147026 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128419 | |||
}} | |||
==PSMD13== | |||
* {{medline-title | |||
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 | |||
}} | |||
==PBX1== | |||
* {{medline-title | |||
|title=Internalization of the TAT-[[PBX1]] fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436118 | |||
|full-text-url=https://sci-hub.do/10.1007/s10529-020-02909-x | |||
}} | |||
==PGAP1== | |||
* {{medline-title | |||
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220 | |||
}} | |||
==RBP4== | |||
* {{medline-title | |||
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats]. | |||
|date=08.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594 | |||
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110 | |||
}} | |||
==SAMD12== | |||
* {{medline-title | |||
|title=Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882010 | |||
}} | |||
==RXFP3== | |||
* {{medline-title | |||
|title=The [[RXFP3]] receptor is functionally associated with cellular responses to oxidative stress and DNA damage. | |||
|date=03.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794429 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932917 | |||
}} | |||
==CEL== | |||
* {{medline-title | |||
|title=Nanocarrier-Mediated Chemo-Immunotherapy Arrested Cancer Progression and Induced Tumor Dormancy in Desmoplastic Melanoma. | |||
|date=28.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30016071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115293 | |||
}} | |||
==UBE3A== | |||
* {{medline-title | |||
|title=Delayed loss of [[UBE3A]] reduces the expression of Angelman syndrome-associated phenotypes. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31143434 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532248 | |||
}} | |||
==SEMA3A== | |||
* {{medline-title | |||
|title=Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging. | |||
|date=05.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661929 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2018.12.021 | |||
}} | |||
==HRH4== | |||
* {{medline-title | |||
|title=Histamime Receptor H4 as a New Therapeutic Target for Age-related Macular Degeneration. | |||
|date=11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30074739 | |||
}} | |||
==VPREB3== | |||
* {{medline-title | |||
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. | |||
|date=19.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985 | |||
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052 | |||
}} | |||
==FRG2== | |||
* {{medline-title | |||
|title=Intergenerational response of steroidogenesis-related genes to maternal malnutrition. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789120 | |||
|full-text-url=https://sci-hub.do/10.1017/S2040174419000060 | |||
}} | |||
==CYP19A1== | |||
* {{medline-title | |||
|title=Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923019 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.016 | |||
}} | |||
==AANAT== | |||
* {{medline-title | |||
|title=Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis. | |||
|date=01.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890428 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993622 | |||
}} | |||
==ALKBH1== | |||
* {{medline-title | |||
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756 | |||
}} | |||
==NLRC5== | |||
* {{medline-title | |||
|title=Methylation of the genes ROD1, [[NLRC5]], and HKR1 is associated with aging in Hainan centenarians. | |||
|date=02.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29394898 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797414 | |||
}} | |||
==CD2AP== | |||
* {{medline-title | |||
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. | |||
|date=28.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389 | |||
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049 | |||
}} | |||
==KIF1B== | |||
* {{medline-title | |||
|title=[[BDNF]] trafficking and signaling impairment during early neurodegeneration is prevented by moderate physical activity. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30135925 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084862 | |||
}} | |||
==CFB== | |||
* {{medline-title | |||
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. | |||
|date=13.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230 | |||
}} | |||
==ID2== | |||
* {{medline-title | |||
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | |||
}} | |||
==ICE1== | |||
* {{medline-title | |||
|title=ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1. | |||
|date=19.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783407 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031079 | |||
}} | |||
==CPT2== | |||
* {{medline-title | |||
|title=The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32729662 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511879 | |||
}} | |||
==CAMSAP1== | |||
* {{medline-title | |||
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720 | |||
}} | |||
==SCX== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==SKI== | |||
* {{medline-title | |||
|title=Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29700792 | |||
|full-text-url=https://sci-hub.do/10.1007/s11684-017-0586-8 | |||
}} | |||
==NKIRAS2== | |||
* {{medline-title | |||
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015 | |||
}} | |||
==XG== | |||
* {{medline-title | |||
|title=The effect of administration media on palatability and ease of swallowing of multiparticulate formulations. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30170024 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ijpharm.2018.08.021 | |||
}} | |||
==S100A13== | |||
* {{medline-title | |||
|title=[[S100A13]] promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α. | |||
|date=23.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30670674 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366962 | |||
}} | |||
==MYCNOS== | |||
* {{medline-title | |||
|title=Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis. | |||
|date=26.01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657277 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831999 | |||
}} | |||
==TCF7== | |||
* {{medline-title | |||
|title=Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29206307 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925424 | |||
}} | |||
==DCTN6== | |||
* {{medline-title | |||
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804 | |||
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011 | |||
}} | |||
==HDC== | |||
* {{medline-title | |||
|title=Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells. | |||
|date=07.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115145 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.02.092 | |||
}} | |||
==CCL28== | |||
* {{medline-title | |||
|title=Age-related chemokine alterations affect IgA secretion and gut immunity in female mice. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32277312 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09877-9 | |||
}} | |||
==GPR19== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==WNT10A== | |||
* {{medline-title | |||
|title=Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development. | |||
|date=01.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31964233 | |||
|full-text-url=https://sci-hub.do/10.1089/scd.2019.0260 | |||
}} | |||
==TRBV19== | |||
* {{medline-title | |||
|title=Perturbed CD8 T cell immunity across universal influenza epitopes in the elderly. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928269 | |||
|full-text-url=https://sci-hub.do/10.1189/jlb.5MA0517-207R | |||
}} | |||
==NPRL3== | |||
* {{medline-title | |||
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9 | |||
}} | |||
==DCLRE1C== | |||
* {{medline-title | |||
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815 | |||
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013 | |||
}} | |||
==ADNP== | |||
* {{medline-title | |||
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513 | |||
}} | |||
==LIFR== | |||
* {{medline-title | |||
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. | |||
|date=15.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304 | |||
}} | |||
==COQ5== | |||
* {{medline-title | |||
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. | |||
|date=18.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522 | |||
}} | |||
==MICU1== | |||
* {{medline-title | |||
|title=Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055 | |||
}} | |||
==SRPK1== | |||
* {{medline-title | |||
|title=[Age-related changes in the content of serine-arginine protein kinase 1 ([[SRPK1]]) in human dermis.] | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322729 | |||
}} | |||
==PCDHGA3== | |||
* {{medline-title | |||
|title=DNA methylation associated with healthy aging of elderly twins. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30136078 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294724 | |||
}} | |||
==RPTOR== | |||
* {{medline-title | |||
|title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052 | |||
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016 | |||
}} | |||
==MYH10== | |||
* {{medline-title | |||
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | |||
}} | |||
==DMPK== | |||
* {{medline-title | |||
|title=Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans. | |||
|date=19.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30878478 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jmb.2019.03.003 | |||
}} | |||
==IFITM3== | |||
* {{medline-title | |||
|title=Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein [[IFITM3]]. | |||
|date=25.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242426 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613042 | |||
}} | |||
==TDG== | |||
* {{medline-title | |||
|title=lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/[[TDG]] axis. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282110 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714223 | |||
}} | |||
==PMS2== | |||
* {{medline-title | |||
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. | |||
|date=25.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.28417 | |||
}} | |||
==JAGN1== | |||
* {{medline-title | |||
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death | |||
|date=13.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814 | |||
}} | |||
==MDN1== | |||
* {{medline-title | |||
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort. | |||
|date=16.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723 | |||
}} | |||
==MARCKSL1== | |||
* {{medline-title | |||
|title=[[MARCKSL1]] Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580842 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952351 | |||
}} | |||
==CCR3== | |||
* {{medline-title | |||
|title=Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro. | |||
|date=04.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32033185 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036885 | |||
}} | |||
==CD209== | |||
* {{medline-title | |||
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569 | |||
}} | |||
==IL22== | |||
* {{medline-title | |||
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015 | |||
}} | |||
==RICTOR== | |||
* {{medline-title | |||
|title=Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31476350 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059097 | |||
}} | |||
==CDR1== | |||
* {{medline-title | |||
|title=Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403498 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786517 | |||
}} | |||
==PES1== | |||
* {{medline-title | |||
|title=Transcription factor RD26 is a key regulator of metabolic reprogramming during dark-induced senescence. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659022 | |||
|full-text-url=https://sci-hub.do/10.1111/nph.15127 | |||
}} | |||
==ATF7== | |||
* {{medline-title | |||
|title=Stress-induced and [[ATF7]]-dependent epigenetic change influences cellular senescence. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31294895 | |||
|full-text-url=https://sci-hub.do/10.1111/gtc.12713 | |||
}} | |||
==NDUFAB1== | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
==AQP5== | |||
* {{medline-title | |||
|title=Submandibular gland-specific inflammaging-induced hyposalivation in the male senescence-accelerated mouse prone -1 line (SAM-P1). | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684147 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09797-3 | |||
}} | |||
==PER3== | |||
* {{medline-title | |||
|title=Effects of [[PER3]] clock gene polymorphisms on aging-related changes of the cerebral cortex. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28900721 | |||
|full-text-url=https://sci-hub.do/10.1007/s00429-017-1513-0 | |||
}} | |||
==TSPYL5== | |||
* {{medline-title | |||
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171 | |||
}} | |||
==CDC20== | |||
* {{medline-title | |||
|title=Premature aging syndrome showing random chromosome number instabilities with [[CDC20]] mutation. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33094908 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681047 | |||
}} | |||
==DIP2A== | |||
* {{medline-title | |||
|title=Blocking the [[FSTL1]]-[[DIP2A]] Axis Improves Anti-tumor Immunity. | |||
|date=14.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30110636 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.07.043 | |||
}} | |||
==ME1== | |||
* {{medline-title | |||
|title=NADP-MALIC ENZYME 1 Affects Germination after Seed Storage in Arabidopsis thaliana. | |||
|date=01.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30388244 | |||
|full-text-url=https://sci-hub.do/10.1093/pcp/pcy213 | |||
}} | |||
==UCHL3== | |||
* {{medline-title | |||
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis. | |||
|date=12.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701 | |||
}} | |||
==HSD17B4== | |||
* {{medline-title | |||
|title=Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein-2 deficiency. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29341299 | |||
|full-text-url=https://sci-hub.do/10.1111/bpa.12586 | |||
}} | |||
==CCL18== | |||
* {{medline-title | |||
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015 | |||
}} | |||
==OLFML3== | |||
* {{medline-title | |||
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z | |||
}} | |||
==DOCK11== | |||
* {{medline-title | |||
|title=[Immunosenescence: The Forefront of Infection and Trophic Control]. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115558 | |||
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00193-3 | |||
}} | |||
==NMS== | |||
* {{medline-title | |||
|title=Uncontrolled Diabetes as an Associated Factor with Dynapenia in Adults Aged 50 Years or Older: Sex Differences. | |||
|date=22.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665234 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243578 | |||
}} | |||
==AKAP17A== | |||
* {{medline-title | |||
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819 | |||
}} | |||
==XRCC4== | |||
* {{medline-title | |||
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081 | |||
}} | |||
==DGAT2== | |||
* {{medline-title | |||
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009 | |||
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6 | |||
}} | |||
==RBM38== | |||
* {{medline-title | |||
|title=Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating [[PTEN]]. | |||
|date=15.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29330147 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340497 | |||
}} | |||
==MCM9== | |||
* {{medline-title | |||
|title=MCM8- and [[MCM9]] Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors. | |||
|date=10.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31509747 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.07.095 | |||
}} | |||
==IGFBP6== | |||
* {{medline-title | |||
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13091 | |||
}} | |||
==AQP2== | |||
* {{medline-title | |||
|title=A bell-shaped pattern of urinary aquaporin-2-bearing extracellular vesicle release in an experimental model of nephronophthisis. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074077 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509436 | |||
}} | |||
==CYB5R3== | |||
* {{medline-title | |||
|title=Overexpression of [[CYB5R3]] and [[NQO1]], two NAD -producing enzymes, mimics aspects of caloric restriction. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706024 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052403 | |||
}} | |||
==XDH== | |||
* {{medline-title | |||
|title=Enhancing xanthine dehydrogenase activity is an effective way to delay leaf senescence and increase rice yield. | |||
|date=11.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162142 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065298 | |||
}} | |||
==FEZ1== | |||
* {{medline-title | |||
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice. | |||
|date=19.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701 | |||
}} | |||
==CD82== | |||
* {{medline-title | |||
|title=Cell-surface phenotyping identifies [[CD36]] and CD97 as novel markers of fibroblast quiescence in lung fibrosis. | |||
|date=01.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952218 | |||
|full-text-url=https://sci-hub.do/10.1152/ajplung.00439.2017 | |||
}} | |||
==IHH== | |||
* {{medline-title | |||
|title=Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway. | |||
|date=01.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32235006 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185126 | |||
}} | |||
==UBC== | |||
* {{medline-title | |||
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261 | |||
}} | |||
==SMARCA5== | |||
* {{medline-title | |||
|title=The epigenetic regulator [[SIRT7]] guards against mammalian cellular senescence induced by ribosomal DNA instability. | |||
|date=13.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728458 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052228 | |||
}} | |||
==HCN4== | |||
* {{medline-title | |||
|title=Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288034 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934612 | |||
}} | |||
==LAT== | |||
* {{medline-title | |||
|title=Is the combined auriculotherapy approach superior to magneto-auriculotherapy alone in aging males with lower urinary tract symptoms? A randomized controlled trial. | |||
|date=16.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30651007 | |||
|full-text-url=https://sci-hub.do/10.1080/13685538.2018.1542673 | |||
}} | |||
==VGLL4== | |||
* {{medline-title | |||
|title=The lncRNA MEG3/miR-16-5p/[[VGLL4]] regulatory axis is involved in etoposide-induced senescence of tumor cells. | |||
|date=03.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33141998 | |||
|full-text-url=https://sci-hub.do/10.1002/jgm.3291 | |||
}} | |||
==PDE2A== | |||
* {{medline-title | |||
|title=TAK-915, a phosphodiesterase 2A inhibitor, ameliorates the cognitive impairment associated with aging in rodent models. | |||
|date=30.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521738 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2019.112192 | |||
}} | |||
==PLCG2== | |||
* {{medline-title | |||
|title=A nonsynonymous mutation in [[PLCG2]] reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31131421 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501 | |||
}} | |||
==GPR37L1== | |||
* {{medline-title | |||
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342 | |||
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9 | |||
}} | |||
==CSF3R== | |||
* {{medline-title | |||
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death | |||
|date=13.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814 | |||
}} | |||
==APOC1== | |||
* {{medline-title | |||
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. | |||
|date=08.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028 | |||
}} | |||
==CCL13== | |||
* {{medline-title | |||
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015 | |||
}} | |||
==PLXNA4== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==KLHL22== | |||
* {{medline-title | |||
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9 | |||
}} | |||
==CES1== | |||
* {{medline-title | |||
|title=[Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog]. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31061351 | |||
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00228 | |||
}} | |||
==GSTM2== | |||
* {{medline-title | |||
|title=Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage. | |||
|date=07.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32574561 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342013 | |||
}} | |||
==KCNK2== | |||
* {{medline-title | |||
|title=Brain age prediction using deep learning uncovers associated sequence variants. | |||
|date=27.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31776335 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881321 | |||
}} | |||
==ETV5== | |||
* {{medline-title | |||
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.26231 | |||
}} | |||
==TLR5== | |||
* {{medline-title | |||
|title=Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30089902 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0395-5 | |||
}} | |||
==XPC== | |||
* {{medline-title | |||
|title=MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene [[XPC]] in Age-related Cataract. | |||
|date=12.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30315181 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185952 | |||
}} | |||
==HS2ST1== | |||
* {{medline-title | |||
|title=Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. | |||
|date=31.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31940721 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999708 | |||
}} | |||
==IFITM1== | |||
* {{medline-title | |||
|title=Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection. | |||
|date=10.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878083 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230210 | |||
}} | |||
==PTP4A3== | |||
* {{medline-title | |||
|title=Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32402127 | |||
|full-text-url=https://sci-hub.do/10.1002/adbi.202000044 | |||
}} | |||
==PDE4C== | |||
* {{medline-title | |||
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637 | |||
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006 | |||
}} | |||
==ARSA== | |||
* {{medline-title | |||
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 | |||
}} | |||
==PRKAA1== | |||
* {{medline-title | |||
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 | |||
}} | |||
==CACNA1S== | |||
* {{medline-title | |||
|title=Increased calcium channel in the lamina propria of aging rat. | |||
|date=31.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31682233 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834399 | |||
}} | |||
==HOXB7== | |||
* {{medline-title | |||
|title=Impact of [[HOXB7]] overexpression on human adipose-derived mesenchymal progenitors. | |||
|date=19.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890185 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423808 | |||
}} | |||
==CCL19== | |||
* {{medline-title | |||
|title=Age-Related Gliosis Promotes Central Nervous System Lymphoma through [[CCL19]]-Mediated Tumor Cell Retention. | |||
|date=16.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31526758 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ccell.2019.08.001 | |||
}} | |||
==LAG3== | |||
* {{medline-title | |||
|title=T Cell Transcriptional Profiling and Immunophenotyping Uncover [[LAG3]] as a Potential Significant Target of Immune Modulation in Multiple Myeloma. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31445183 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952061 | |||
}} | |||
==SFRP2== | |||
* {{medline-title | |||
|title=[Role and alterations of DNA methylation during the aging and cancer]. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647 | |||
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927 | |||
}} | |||
==SYNE1== | |||
* {{medline-title | |||
|title=Nesprin-1 impact on tumorigenic cell phenotypes. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31741263 | |||
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05184-w | |||
}} | |||
==BACH2== | |||
* {{medline-title | |||
|title=Age-related changes in the [[BACH2]] and [[PRDM1]] genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients. | |||
|date=17.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654767 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337793 | |||
}} | |||
==HIRA== | |||
* {{medline-title | |||
|title=Pak2 kinase promotes cellular senescence and organismal aging. | |||
|date=02.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31209047 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613284 | |||
}} | |||
==CXCR1== | |||
* {{medline-title | |||
|title=Harmful neutrophil subsets in patients with ischemic stroke: Association with disease severity. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31355307 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624098 | |||
}} | |||
==HIF3A== | |||
* {{medline-title | |||
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220 | |||
}} | |||
==GPR101== | |||
* {{medline-title | |||
|title=Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163355 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663685 | |||
}} | |||
==HDAC11== | |||
* {{medline-title | |||
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice. | |||
|date=19.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701 | |||
}} | |||
==SRI== | |||
* {{medline-title | |||
|title=The Role of Aging, Drug Dependence, and Hepatitis C Comorbidity in Alcoholism Cortical Compromise. | |||
|date=01.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29541774 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875381 | |||
}} | |||
==GRM2== | |||
* {{medline-title | |||
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015 | |||
}} | |||
==SRM== | |||
* {{medline-title | |||
|title=[Geriatric specificities of localized renal cell carcinoma]. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771769 | |||
|full-text-url=https://sci-hub.do/10.1016/j.purol.2019.08.281 | |||
}} | |||
==SLC41A1== | |||
* {{medline-title | |||
|title=Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis. | |||
|date=08.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31076559 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535063 | |||
}} | |||
==SV2C== | |||
* {{medline-title | |||
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247 | |||
}} | |||
==CCND1== | |||
* {{medline-title | |||
|title=Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592933 | |||
|full-text-url=https://sci-hub.do/10.1016/j.archoralbio.2020.104819 | |||
}} | |||
==RAB1B== | |||
* {{medline-title | |||
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 | |||
}} | |||
==CD59== | |||
* {{medline-title | |||
|title=Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156458 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529780 | |||
}} | |||
==SLC1A5== | |||
* {{medline-title | |||
|title=[[SLC1A5]] glutamine transporter is a target of [[MYC]] and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909319 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516164 | |||
}} | |||
==TP53RK== | |||
* {{medline-title | |||
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. | |||
|date=11.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604 | |||
}} | |||
==IAPP== | |||
* {{medline-title | |||
|title=Protein aggregates and proteostasis in aging: Amylin and β-cell function. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580826 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.03.010 | |||
}} | |||
==PAX8== | |||
* {{medline-title | |||
|title=Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging. | |||
|date=13.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31518338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781991 | |||
}} | |||
==GPR173== | |||
* {{medline-title | |||
|title=Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163355 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663685 | |||
}} | |||
==TES== | |||
* {{medline-title | |||
|title=The Effects of Electrical Stimulation Pulse Duration on Lingual Palatal Pressure Measures During Swallowing in Healthy Older Adults. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820657 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456514 | |||
}} | |||
==NBN== | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 | |||
}} | |||
==IRF5== | |||
* {{medline-title | |||
|title=Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28905935 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672072 | |||
}} | |||
==NOTCH4== | |||
* {{medline-title | |||
|title=Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920157 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595581 | |||
}} | |||
==BMPR1B== | |||
* {{medline-title | |||
|title=Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503129 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.08.018 | |||
}} | |||
==IL9== | |||
* {{medline-title | |||
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640 | |||
}} | |||
==GSTZ1== | |||
* {{medline-title | |||
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | |||
}} | |||
==IFI27== | |||
* {{medline-title | |||
|title=Ultraviolet B irradiation-induced keratinocyte senescence and impaired development of 3D epidermal reconstruct. | |||
|date=01.06.2021 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33151171 | |||
|full-text-url=https://sci-hub.do/10.2478/acph-2021-0011 | |||
}} | |||
==ADRA2B== | |||
* {{medline-title | |||
|title=Aging and the Combined effects of [[ADRA2B]] and CB1 deletions on Affective Working Memory. | |||
|date=11.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30858399 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411975 | |||
}} | |||
==NCOR2== | |||
* {{medline-title | |||
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | |||
|date=25.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | |||
}} | |||
==ASPA== | |||
* {{medline-title | |||
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637 | |||
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006 | |||
}} | |||
==SMPD1== | |||
* {{medline-title | |||
|title=Alterations in Lipid Profile of the Aging Kidney Identified by MALDI Imaging Mass Spectrometry. | |||
|date=05.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31244212 | |||
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00108 | |||
}} | |||
==GPX3== | |||
* {{medline-title | |||
|title=Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814699 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857780 | |||
}} | |||
==NDN== | |||
* {{medline-title | |||
|title=The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087674 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066563 | |||
}} | |||
==ADAMTS9== | |||
* {{medline-title | |||
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13091 | |||
}} | |||
==PRG4== | |||
* {{medline-title | |||
|title=Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis. | |||
|date=08.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415892 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821202 | |||
}} | |||
==PAFAH2== | |||
* {{medline-title | |||
|title=Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30521374 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404557 | |||
}} | |||
==CYP3A5== | |||
* {{medline-title | |||
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906 | |||
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442 | |||
}} | |||
==THEMIS== | |||
* {{medline-title | |||
|title=Lifetime benefits of early detection and treatment of diabetic kidney disease. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31150444 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544227 | |||
}} | |||
==FGF6== | |||
* {{medline-title | |||
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. | |||
|date=06.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057 | |||
}} | |||
==TPP1== | |||
* {{medline-title | |||
|title=FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping. | |||
|date=03.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33086033 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2020.10.004 | |||
}} | |||
==IGSF1== | |||
* {{medline-title | |||
|title=Age-related gene and miRNA expression changes in airways of healthy individuals. | |||
|date=06.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842487 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403379 | |||
}} | |||
==KDM3A== | |||
* {{medline-title | |||
|title=[[KDM3A]] and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization. | |||
|date=22.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704649 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888768 | |||
}} | |||
==HNF4A== | |||
* {{medline-title | |||
|title=Hepatocyte Nuclear Factor-4α P2 Promoter Variants Are Associated With the Risk of Metabolic Syndrome and Testosterone Deficiency in Aging Taiwanese Men. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415809 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jsxm.2018.09.012 | |||
}} | |||
==KCNC3== | |||
* {{medline-title | |||
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723 | |||
}} | |||
==JARID2== | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
==FAH== | |||
* {{medline-title | |||
|title=Oxaloacetate decarboxylase [[FAH]]D1 - a new regulator of mitochondrial function and senescence. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055189 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.07.007 | |||
}} | |||
==CHRM4== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==GEN1== | |||
* {{medline-title | |||
|title=US acculturation and poor sleep among an intergenerational cohort of adult Latinos in Sacramento, California. | |||
|date=01.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30544165 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424080 | |||
}} | |||
==PDE4B== | |||
* {{medline-title | |||
|title=Phosphodiesterase-4B as a Therapeutic Target for Cognitive Impairment and Obesity-Related Metabolic Diseases. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28956331 | |||
|full-text-url=https://sci-hub.do/10.1007/978-3-319-58811-7_5 | |||
}} | |||
==TYROBP== | |||
* {{medline-title | |||
|title=[[TREM2]] triggers microglial density and age-related neuronal loss. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548312 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266 | |||
}} | |||
==PRLR== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==ABHD12== | |||
* {{medline-title | |||
|title=Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout [[ABHD12]] Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31213981 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555221 | |||
}} | |||
==RPL37== | |||
* {{medline-title | |||
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261 | |||
}} | |||
==TRPV5== | |||
* {{medline-title | |||
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433 | |||
}} | |||
==IFT140== | |||
* {{medline-title | |||
|title=The Role of [[IFT140]] in Osteogenesis of Adult Mice Long Bone. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31034313 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669857 | |||
}} | |||
==TCF15== | |||
* {{medline-title | |||
|title=Loss of Neurogenesis in Aging Hydra. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912256 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586502 | |||
}} | |||
==ANK3== | |||
* {{medline-title | |||
|title=Age-related atrophy of cortical thickness and genetic effect of [[ANK3]] gene in first episode MDD patients. | |||
|date=26.08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32911427 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490581 | |||
}} | |||
==MSH6== | |||
* {{medline-title | |||
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. | |||
|date=25.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.28417 | |||
}} | |||
==VEGFD== | |||
* {{medline-title | |||
|title=Single-Arm Resistance Training Study to Determine the Relationship between Training Outcomes and Muscle Growth Factor mRNAs in Older Adults Consuming Numerous Medications and Supplements. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29380855 | |||
|full-text-url=https://sci-hub.do/10.1007/s12603-017-0913-4 | |||
}} | |||
==LAGE3== | |||
* {{medline-title | |||
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. | |||
|date=11.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604 | |||
}} | |||
==MFN1== | |||
* {{medline-title | |||
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363 | |||
}} | |||
==ESRG== | |||
* {{medline-title | |||
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition. | |||
|date=10.04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057 | |||
}} | |||
==BCL2L1== | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
==CDC73== | |||
* {{medline-title | |||
|title=Down-regulation of cancer-associated gene [[CDC73]] contributes to cellular senescence. | |||
|date=23.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29621547 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.228 | |||
}} | |||
==SIL1== | |||
* {{medline-title | |||
|title=[[SIL1]], the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology. | |||
|date=10.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29666155 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992605 | |||
}} | |||
==TGFBR1== | |||
* {{medline-title | |||
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z | |||
}} | |||
==MMP7== | |||
* {{medline-title | |||
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478 | |||
}} | |||
==CSAD== | |||
* {{medline-title | |||
|title=The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway. | |||
|date=19.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131986 | |||
|full-text-url=https://sci-hub.do/10.1039/c8fo00740c | |||
}} | |||
==ERCC6== | |||
* {{medline-title | |||
|title=Two Cockayne Syndrome patients with a novel splice site mutation - clinical and metabolic analyses. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29944916 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.001 | |||
}} | |||
==DUSP2== | |||
* {{medline-title | |||
|title=Aging Increases Hippocampal [[DUSP2]] by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31293510 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603139 | |||
}} | |||
==FOSL2== | |||
* {{medline-title | |||
|title=LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis. | |||
|date=03.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32149459 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132339 | |||
}} | |||
==DDIT3== | |||
* {{medline-title | |||
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528 | |||
}} | |||
==HSPA1L== | |||
* {{medline-title | |||
|title=Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the [[HSPA1L]]-mitophagy pathway. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31965731 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059143 | |||
}} | |||
==RPS6KB1== | |||
* {{medline-title | |||
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528 | |||
}} | |||
==DROSHA== | |||
* {{medline-title | |||
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072 | |||
}} | |||
==FCGR2A== | |||
* {{medline-title | |||
|title=Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells. | |||
|date=03.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377747 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710049 | |||
}} | |||
==SERPINA1== | |||
* {{medline-title | |||
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13091 | |||
}} | |||
==IL2RA== | |||
* {{medline-title | |||
|title=Dynamic demethylation of the [[IL2RA]] promoter during in vitro CD4+ T cell activation in association with [[IL2RA]] expression. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30096258 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140818 | |||
}} | |||
==AGAP2== | |||
* {{medline-title | |||
|title=Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating [[AGAP2]]. | |||
|date=05.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386624 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710058 | |||
}} | |||
==U2AF1== | |||
* {{medline-title | |||
|title=Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs. | |||
|date=05.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32141009 | |||
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01509-z | |||
}} | |||
==SLC19A1== | |||
* {{medline-title | |||
|title=Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer. | |||
|date=30.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29682186 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908287 | |||
}} | |||
==SAA2== | |||
* {{medline-title | |||
|title=Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617422 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884545 | |||
}} | |||
==COL2A1== | |||
* {{medline-title | |||
|title=Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis. | |||
|date=08.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415892 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821202 | |||
}} | |||
==STC1== | |||
* {{medline-title | |||
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13091 | |||
}} | |||
==JAM3== | |||
* {{medline-title | |||
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456 | |||
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341 | |||
}} | |||
==NDUFS3== | |||
* {{medline-title | |||
|title=Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10). | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477336 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.025 | |||
}} | |||
==NPRL2== | |||
* {{medline-title | |||
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9 | |||
}} | |||
==SYT1== | |||
* {{medline-title | |||
|title=Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29670520 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893842 | |||
}} | |||
==SERPINB2== | |||
* {{medline-title | |||
|title=An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through [[SERPINB2]]. | |||
|date=03.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080015 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612665 | |||
}} | |||
==EIF2B4== | |||
* {{medline-title | |||
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 | |||
}} | |||
==LRRC34== | |||
* {{medline-title | |||
|title=The polygenic nature of telomere length and the anti-ageing properties of lithium. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372618 | |||
}} | |||
==ACAD9== | |||
* {{medline-title | |||
|title=Identification of a novel mitochondrial complex I assembly factor ACDH-12 in Caenorhabditis elegans. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540318 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mito.2018.02.010 | |||
}} | |||
==EXOC7== | |||
* {{medline-title | |||
|title=[[PTBP1]]-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. | |||
|date=09.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990503 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048363 | |||
}} | |||
==VEGFC== | |||
* {{medline-title | |||
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13091 | |||
}} | |||
==KCNE4== | |||
* {{medline-title | |||
|title=Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice. | |||
|date=29.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29844497 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974354 | |||
}} | |||
==TOMM20== | |||
* {{medline-title | |||
|title=Effect of aging on mitochondria and metabolism of bovine granulosa cells. | |||
|date=13.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32921645 | |||
|full-text-url=https://sci-hub.do/10.1262/jrd.2020-071 | |||
}} | |||
==ENC1== | |||
* {{medline-title | |||
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456 | |||
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341 | |||
}} | |||
==SSBP2== | |||
* {{medline-title | |||
|title=Genetic associations with age of menopause in familial longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937 | |||
}} | |||
==TPX2== | |||
* {{medline-title | |||
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578 | |||
}} | |||
==RBMXL1== | |||
* {{medline-title | |||
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort. | |||
|date=16.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723 | |||
}} | |||
==BMP7== | |||
* {{medline-title | |||
|title=Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting [[BMP7]]. | |||
|date=11.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31829291 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907335 | |||
}} | |||
==CTSL== | |||
* {{medline-title | |||
|title=Cathepsin L deficiency results in reactive oxygen species (ROS) accumulation and vascular cells activation. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29041825 | |||
|full-text-url=https://sci-hub.do/10.1080/10715762.2017.1393665 | |||
}} | |||
==GRB2== | |||
* {{medline-title | |||
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice. | |||
|date=21.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397 | |||
}} | |||
==PLA2R1== | |||
* {{medline-title | |||
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922 | |||
}} | |||
==SF1== | |||
* {{medline-title | |||
|title=Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576894 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.12.034 | |||
}} | |||
==STOML2== | |||
* {{medline-title | |||
|title=Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29201274 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672147 | |||
}} | |||
==IRGM== | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
==MORF4L1== | |||
* {{medline-title | |||
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. | |||
|date=20.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988 | |||
}} | |||
==WWP1== | |||
* {{medline-title | |||
|title=The ubiquitin ligase [[WWP1]] contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart. | |||
|date=01.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32822210 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717125 | |||
}} | |||
==THBS1== | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 | |||
}} | |||
==CCAR2== | |||
* {{medline-title | |||
|title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500 | |||
}} | |||
==BRD3== | |||
* {{medline-title | |||
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004 | |||
}} | |||
==PPP3CB== | |||
* {{medline-title | |||
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720 | |||
}} | |||
==GPX7== | |||
* {{medline-title | |||
|title=Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659168 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052468 | |||
}} | |||
==TDP1== | |||
* {{medline-title | |||
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis. | |||
|date=12.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701 | |||
}} | |||
==NOL12== | |||
* {{medline-title | |||
|title=[[NOL12]] Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging. | |||
|date=15.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988155 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549468 | |||
}} | |||
==NMRK2== | |||
* {{medline-title | |||
|title=Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283350 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156423 | |||
}} | |||
==PIP5K1C== | |||
* {{medline-title | |||
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748 | |||
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724 | |||
}} | |||
==DCAF17== | |||
* {{medline-title | |||
|title=Deletion of [[DDB1]]- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. | |||
|date=15.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907856 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003934 | |||
}} | |||
==WFDC2== | |||
* {{medline-title | |||
|title=Differences in biomarkers and molecular pathways according to age for patients with HFrEF. | |||
|date=01.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002110 | |||
|full-text-url=https://sci-hub.do/10.1093/cvr/cvaa279 | |||
}} | |||
==DSC1== | |||
* {{medline-title | |||
|title=HDLs and the pathogenesis of atherosclerosis. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29561322 | |||
|full-text-url=https://sci-hub.do/10.1097/HCO.0000000000000508 | |||
}} | |||
==ASB7== | |||
* {{medline-title | |||
|title=[[ASB7]] Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33251222 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674779 | |||
}} | |||
==HTRA1== | |||
* {{medline-title | |||
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 | |||
}} | |||
==KPNA2== | |||
* {{medline-title | |||
|title=Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-[[CRY1]] Transgenic Mice. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31179341 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507265 | |||
}} | |||
==PRDM16== | |||
* {{medline-title | |||
|title=Assessment of the Aging of the Brown Adipose Tissue by F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna . | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116163 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079616 | |||
}} | |||
==EHF== | |||
* {{medline-title | |||
|title=Extended high frequency hearing and speech perception implications in adults and children. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32111404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431381 | |||
}} | |||
==SLC26A2== | |||
* {{medline-title | |||
|title=Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31914611 | |||
|full-text-url=https://sci-hub.do/10.1096/fj.201901040RR | |||
}} | |||
==SLC2A4== | |||
* {{medline-title | |||
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 | |||
}} | |||
==GGCX== | |||
* {{medline-title | |||
|title=Multiple Modes of Vitamin K Actions in Aging-Related Musculoskeletal Disorders. | |||
|date=11.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31212662 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600274 | |||
}} | |||
==OTX2== | |||
* {{medline-title | |||
|title=Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice. | |||
|date=01.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29337233 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819331 | |||
}} | |||
==DDI2== | |||
* {{medline-title | |||
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498 | |||
}} | |||
==NEIL3== | |||
* {{medline-title | |||
|title=Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31167196 | |||
|full-text-url=https://sci-hub.do/10.1159/000500091 | |||
}} | |||
==GSTP1== | |||
* {{medline-title | |||
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | |||
}} | |||
==SCN5A== | |||
* {{medline-title | |||
|title=[Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug]. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30175758 | |||
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00114 | |||
}} | |||
==FBXO31== | |||
* {{medline-title | |||
|title=The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence. | |||
|date=19.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945 | |||
}} | |||
==ENO1== | |||
* {{medline-title | |||
|title=Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32355541 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191177 | |||
}} | |||
==FLT3== | |||
* {{medline-title | |||
|title=Sequential acquisition of mutations in myelodysplastic syndromes. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821 | |||
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828 | |||
}} | |||
==NFKB1== | |||
* {{medline-title | |||
|title=[[NFKB1]] gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32002656 | |||
|full-text-url=https://sci-hub.do/10.1007/s00277-020-03935-5 | |||
}} | |||
==DCTN3== | |||
* {{medline-title | |||
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804 | |||
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011 | |||
}} | |||
==MUS81== | |||
* {{medline-title | |||
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287 | |||
}} | |||
==DIAPH1== | |||
* {{medline-title | |||
|title=Diaphanous 1 ([[DIAPH1]]) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966194 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082178 | |||
}} | |||
==ING1== | |||
* {{medline-title | |||
|title=Impaired DNA demethylation of C/EBP sites causes premature aging. | |||
|date=01.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29884649 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049513 | |||
}} | |||
==BAZ1A== | |||
* {{medline-title | |||
|title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells. | |||
|date=15.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023 | |||
}} | |||
==NUPR1== | |||
* {{medline-title | |||
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327 | |||
}} | |||
==DNMT3L== | |||
* {{medline-title | |||
|title=Transient [[DNMT3L]] Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32195249 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064442 | |||
}} | |||
==TFPI== | |||
* {{medline-title | |||
|title=Identification of cardiovascular health gene variants related to longevity in a Chinese population. | |||
|date=07.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32897244 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521493 | |||
}} | |||
==MEST== | |||
* {{medline-title | |||
|title=Improving specific autobiographical memory in older adults: impacts on mood, social problem solving, and functional limitations. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825508 | |||
|full-text-url=https://sci-hub.do/10.1080/13825585.2017.1365815 | |||
}} | |||
==CHL1== | |||
* {{medline-title | |||
|title=Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B. | |||
|date=07.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182634 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687901 | |||
}} | |||
==SFRP1== | |||
* {{medline-title | |||
|title=[Role and alterations of DNA methylation during the aging and cancer]. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647 | |||
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927 | |||
}} | |||
==MIB1== | |||
* {{medline-title | |||
|title=Immunohistochemical detection of senescence markers in human sarcomas. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31899047 | |||
|full-text-url=https://sci-hub.do/10.1016/j.prp.2019.152800 | |||
}} | |||
==KDM6B== | |||
* {{medline-title | |||
|title=Histone demethylase [[KDM6B]] regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30825201 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.28431 | |||
}} | |||
==WNT16== | |||
* {{medline-title | |||
|title=Inducible [i]Wnt16[/i] inactivation: [[WNT16]] regulates cortical bone thickness in adult mice. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29530924 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886037 | |||
}} | |||
==MYOC== | |||
* {{medline-title | |||
|title=Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells. | |||
|date=28.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389787 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311499 | |||
}} | |||
==CYP17A1== | |||
* {{medline-title | |||
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246 | |||
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128 | |||
}} | |||
==ADIPOR1== | |||
* {{medline-title | |||
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318 | |||
}} | |||
==CTSA== | |||
* {{medline-title | |||
|title=A [[CTSA]]-based consultation service to advance research on special and underserved populations. | |||
|date=16.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33244406 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681147 | |||
}} | |||
==MYT1== | |||
* {{medline-title | |||
|title=ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the [[MYT1]]-Egln3-Sirt1 Axis. | |||
|date=01.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33038325 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ymthe.2020.09.037 | |||
}} | |||
==WASL== | |||
* {{medline-title | |||
|title=Loss of Wasl improves pancreatic cancer outcome. | |||
|date=21.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434991 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259520 | |||
}} | |||
==PUM1== | |||
* {{medline-title | |||
|title=Identification of reference genes for RT-qPCR data normalisation in aging studies. | |||
|date=27.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562345 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764958 | |||
}} | |||
==SPG7== | |||
* {{medline-title | |||
|title=Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration. | |||
|date=21.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467464 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833341 | |||
}} | |||
==FOXC1== | |||
* {{medline-title | |||
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 | |||
}} | |||
==MARK1== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
==EXO1== | |||
* {{medline-title | |||
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815 | |||
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013 | |||
}} | |||
==CYB5A== | |||
* {{medline-title | |||
|title=11-Oxygenated C19 Steroids Do Not Decline With Age in Women. | |||
|date=01.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753518 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525564 | |||
}} | |||
==RPE65== | |||
* {{medline-title | |||
|title=Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30091312 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085187 | |||
}} | |||
==CRISPLD2== | |||
* {{medline-title | |||
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. | |||
|date=20.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988 | |||
}} | |||
==MAPK10== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==CCNA1== | |||
* {{medline-title | |||
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. | |||
|date=02.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654 | |||
}} | |||
==ZNF521== | |||
* {{medline-title | |||
|title=Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells. | |||
|date=21.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31227697 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588633 | |||
}} | |||
==XPO1== | |||
* {{medline-title | |||
|title=Nuclear Export Inhibition Enhances HLH-30/[[TFEB]] Activity, Autophagy, and Lifespan. | |||
|date=15.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768192 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991088 | |||
}} | |||
==ITGA5== | |||
* {{medline-title | |||
|title=Kaempferol alleviates the reduction of developmental competence during aging of porcine oocytes. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31486245 | |||
|full-text-url=https://sci-hub.do/10.1111/asj.13280 | |||
}} | |||
==IFIH1== | |||
* {{medline-title | |||
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569 | |||
}} | |||
==USP28== | |||
* {{medline-title | |||
|title=Genetic interrogation of replicative senescence uncovers a dual role for [[USP28]] in coordinating the p53 and [[GATA4]] branches of the senescence program. | |||
|date=01.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089421 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710139 | |||
}} | |||
==KRT19== | |||
* {{medline-title | |||
|title=Characterization of Krt19 allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187500 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778700 | |||
}} | |||
==VPS13D== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
==EIF2B3== | |||
* {{medline-title | |||
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 | |||
}} | |||
==SAMD10== | |||
* {{medline-title | |||
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015 | |||
}} | |||
==MERTK== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==GNG4== | |||
* {{medline-title | |||
|title=Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for [[GNG4]] and [[KCNQ2]] Genes. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338302 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098 | |||
}} | |||
==TRPM6== | |||
* {{medline-title | |||
|title=Role of kinase-coupled TRP channels in mineral homeostasis. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129644 | |||
|full-text-url=https://sci-hub.do/10.1016/j.pharmthera.2017.11.003 | |||
}} | |||
==MYLPF== | |||
* {{medline-title | |||
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. | |||
|date=15.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004 | |||
}} | |||
==G6PC== | |||
* {{medline-title | |||
|title=Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of [[TP53]]. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941676 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106910 | |||
}} | |||
==DNAJB9== | |||
* {{medline-title | |||
|title=[[DNAJB9]] Inhibits p53-Dependent Oncogene-Induced Senescence and Induces Cell Transformation. | |||
|date=30.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32264658 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191047 | |||
}} | |||
==MSRA== | |||
* {{medline-title | |||
|title=Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30456853 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351846 | |||
}} | |||
==DKK2== | |||
* {{medline-title | |||
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448 | |||
}} | |||
==CEBPD== | |||
* {{medline-title | |||
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | |||
}} | |||
==PPP1R3C== | |||
* {{medline-title | |||
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171 | |||
}} | |||
==VIPR2== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==ITGA2B== | |||
* {{medline-title | |||
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637 | |||
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006 | |||
}} | |||
==IGF2BP3== | |||
* {{medline-title | |||
|title=Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth. | |||
|date=01.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888162 | |||
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b00833 | |||
}} | |||
==CRY2== | |||
* {{medline-title | |||
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. | |||
|date=21.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686 | |||
}} | |||
==TRPC7== | |||
* {{medline-title | |||
|title=Nociceptive transient receptor potential canonical 7 ([[TRPC7]]) mediates aging-associated tumorigenesis induced by ultraviolet B. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31755176 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974716 | |||
}} | |||
==PARK7== | |||
* {{medline-title | |||
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073 | |||
}} | |||
==HBD== | |||
* {{medline-title | |||
|title=Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026271 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485713 | |||
}} | |||
==VPS35== | |||
* {{medline-title | |||
|title=Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development. | |||
|date=16.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654520 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359594 | |||
}} | |||
==ABCE1== | |||
* {{medline-title | |||
|title=Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain. | |||
|date=27.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485811 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354779 | |||
}} | |||
==PRDX6== | |||
* {{medline-title | |||
|title=Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31417400 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684764 | |||
}} | |||
==RHCG== | |||
* {{medline-title | |||
|title=Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma. | |||
|date=06.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170090 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594797 | |||
}} | |||
==CREM== | |||
* {{medline-title | |||
|title=Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250567 | |||
|full-text-url=https://sci-hub.do/10.1111/andr.12665 | |||
}} | |||
==ZFPM2== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==ABCG1== | |||
* {{medline-title | |||
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770 | |||
}} | |||
==MED25== | |||
* {{medline-title | |||
|title=The [i]HAC1[/i] histone acetyltransferase promotes leaf senescence and regulates the expression of [i]ERF022[/i]. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468026 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710649 | |||
}} | |||
==CDKN1B== | |||
* {{medline-title | |||
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318 | |||
}} | |||
==SELENBP1== | |||
* {{medline-title | |||
|title=A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31557719 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812014 | |||
}} | |||
==LY6D== | |||
* {{medline-title | |||
|title=[[LY6D]]-induced macropinocytosis as a survival mechanism of senescent cells. | |||
|date=09.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168631 | |||
|full-text-url=https://sci-hub.do/10.1074/jbc.RA120.013500 | |||
}} | |||
==PRKCB== | |||
* {{medline-title | |||
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells. | |||
|date=18.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757 | |||
}} | |||
==PLD3== | |||
* {{medline-title | |||
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort. | |||
|date=16.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723 | |||
}} | |||
==SYNJ1== | |||
* {{medline-title | |||
|title=Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer's Disease. | |||
|date=05.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29874583 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040810 | |||
}} | |||
==MYOF== | |||
* {{medline-title | |||
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. | |||
|date=08.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028 | |||
}} | |||
==SLC7A11== | |||
* {{medline-title | |||
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes. | |||
|date=28.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560 | |||
}} | |||
==CARM1== | |||
* {{medline-title | |||
|title=[[CARM1]] regulates senescence during airway epithelial cell injury in COPD pathogenesis. | |||
|date=01.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31461302 | |||
|full-text-url=https://sci-hub.do/10.1152/ajplung.00441.2018 | |||
}} | |||
==GPD2== | |||
* {{medline-title | |||
|title=Switching off [[IMMP2L]] signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808012 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993829 | |||
}} | |||
==RELB== | |||
* {{medline-title | |||
|title=New control of the senescence barrier in breast cancer. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158912 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051141 | |||
}} | |||
==ARRB2== | |||
* {{medline-title | |||
|title=Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304635 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801044 | |||
}} | |||
==THRB== | |||
* {{medline-title | |||
|title=Age-associated increase of thyroid hormone receptor β gene promoter methylation coexists with decreased gene expression. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733698 | |||
|full-text-url=https://sci-hub.do/10.1080/07435800.2018.1469648 | |||
}} | |||
==LY86== | |||
* {{medline-title | |||
|title=Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31280115 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732230 | |||
}} | |||
==HAMP== | |||
* {{medline-title | |||
|title=A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29408220 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.01.044 | |||
}} | |||
==GSTO1== | |||
* {{medline-title | |||
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | |||
}} | |||
==ADH1B== | |||
* {{medline-title | |||
|title=Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466069 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2018.11.007 | |||
}} | |||
==APOBEC1== | |||
* {{medline-title | |||
|title=Loss of [[APOBEC1]] RNA-editing function in microglia exacerbates age-related CNS pathophysiology. | |||
|date=12.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167375 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740644 | |||
}} | |||
==DMP1== | |||
* {{medline-title | |||
|title=Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978155 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029870 | |||
}} | |||
==AMPH== | |||
* {{medline-title | |||
|title=Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood. | |||
|date=01.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29792867 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026035 | |||
}} | |||
==ILDR1== | |||
* {{medline-title | |||
|title=Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment. | |||
|date=23.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31645637 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811684 | |||
}} | |||
==IGF2R== | |||
* {{medline-title | |||
|title=Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks. | |||
|date=05-06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29554514 | |||
|full-text-url=https://sci-hub.do/10.1016/j.archger.2018.03.004 | |||
}} | |||
==MCUR1== | |||
* {{medline-title | |||
|title=Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055 | |||
}} | |||
==GLA== | |||
* {{medline-title | |||
|title=TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25. | |||
|date=17.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769448 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012510 | |||
}} | |||
==JDP2== | |||
* {{medline-title | |||
|title=Jun dimerization protein 2 controls hypoxia-induced replicative senescence via both the p16 -pRb and Arf-p53 pathways. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29123987 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666393 | |||
}} | |||
==CAPRIN1== | |||
* {{medline-title | |||
|title=Reduced Levels of the Synaptic Functional Regulator FMRP in Dentate Gyrus of the Aging Sprague-Dawley Rat. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29218006 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703695 | |||
}} | |||
==DPT== | |||
* {{medline-title | |||
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483 | |||
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0 | |||
}} | |||
==SLC22A23== | |||
* {{medline-title | |||
|title=Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603369 | |||
|full-text-url=https://sci-hub.do/10.1111/jgh.14149 | |||
}} | |||
==MEFV== | |||
* {{medline-title | |||
|title=The grandfather's fever. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31401792 | |||
|full-text-url=https://sci-hub.do/10.1007/s10067-019-04741-9 | |||
}} | |||
==PSMD14== | |||
* {{medline-title | |||
|title=Upregulation of deubiquitinase [[PSMD14]] in lung adenocarcinoma (LUAD) and its prognostic significance. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32226511 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086243 | |||
}} | |||
==ANK2== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
==DSE== | |||
* {{medline-title | |||
|title=Impact of Intensive Lifestyle Intervention on Disability-Free Life Expectancy: The Look AHEAD Study. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545462 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911793 | |||
}} | |||
==SUMO1== | |||
* {{medline-title | |||
|title=[[SUMO1]]-conjugation is altered during normal aging but not by increased amyloid burden. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29633471 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052395 | |||
}} | |||
==HBM== | |||
* {{medline-title | |||
|title=The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis. | |||
|date=25.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31553309 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781972 | |||
}} | |||
==ALOX5== | |||
* {{medline-title | |||
|title=Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme. | |||
|date=01.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642348 | |||
|full-text-url=https://sci-hub.do/10.1089/ars.2019.7751 | |||
}} | |||
==PMP22== | |||
* {{medline-title | |||
|title=Role of microRNAs in senescence and its contribution to peripheral neuropathy in the arsenic exposed population of West Bengal, India. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29107899 | |||
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2017.09.063 | |||
}} | |||
==SRL== | |||
* {{medline-title | |||
|title=Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment. | |||
|date=04-06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32432936 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250001 | |||
}} | |||
==VAMP8== | |||
* {{medline-title | |||
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327 | |||
}} | |||
==PSMD11== | |||
* {{medline-title | |||
|title=The effect and mechanism of 19S proteasome [[PSMD11]]/Rpn6 subunit in D-Galactose induced mimetic aging models. | |||
|date=01.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32450067 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.112093 | |||
}} | |||
==GALC== | |||
* {{medline-title | |||
|title=Analysis of age-related changes in psychosine metabolism in the human brain. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29481565 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826537 | |||
}} | |||
==HNRNPM== | |||
* {{medline-title | |||
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819 | |||
}} | |||
==FZD4== | |||
* {{medline-title | |||
|title=MiR-1292 Targets [[FZD4]] to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574422 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284756 | |||
}} | |||
==GNE== | |||
* {{medline-title | |||
|title=Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2 mice. | |||
|date=10.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33300446 | |||
|full-text-url=https://sci-hub.do/10.1080/15548627.2020.1850008 | |||
}} | |||
==DCTN2== | |||
* {{medline-title | |||
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804 | |||
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011 | |||
}} | |||
==ETV6== | |||
* {{medline-title | |||
|title=[[FOXO1]] and [[ETV6]] genes may represent novel regulators of splicing factor expression in cellular senescence. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088951 | |||
|full-text-url=https://sci-hub.do/10.1096/fj.201801154R | |||
}} | |||
==DRD4== | |||
* {{medline-title | |||
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915 | |||
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711 | |||
}} | |||
==FANCC== | |||
* {{medline-title | |||
|title=Fanconi Anemia complementation group C protein in metabolic disorders. | |||
|date=21.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29930218 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046246 | |||
}} | |||
==CALR== | |||
* {{medline-title | |||
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454 | |||
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0 | |||
}} | |||
==ITGB2== | |||
* {{medline-title | |||
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788 | |||
}} | |||
==NKX6-1== | |||
* {{medline-title | |||
|title=The dynamic methylome of islets in health and disease. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500828 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768570 | |||
}} | |||
==SMN2== | |||
* {{medline-title | |||
|title=Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. | |||
|date=01.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589162 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819103 | |||
}} | |||
==FOXL2== | |||
* {{medline-title | |||
|title=Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor. | |||
|date=09.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29523193 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845161 | |||
}} | |||
==PPP2R1A== | |||
* {{medline-title | |||
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 | |||
}} | |||
==SOX11== | |||
* {{medline-title | |||
|title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress. | |||
|date=10.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741 | |||
}} | |||
==EDEM1== | |||
* {{medline-title | |||
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009 | |||
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6 | |||
}} | |||
==GCNT2== | |||
* {{medline-title | |||
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature. | |||
|date=18.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778 | |||
}} | |||
==CRYAB== | |||
* {{medline-title | |||
|title=Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells. | |||
|date=28.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389787 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311499 | |||
}} | |||
==ESR1== | |||
* {{medline-title | |||
|title=Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement. | |||
|date=05.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416771 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788639 | |||
}} | |||
==ADD2== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
==DLL4== | |||
* {{medline-title | |||
|title=Dynamic regulation of [[NOTCH1]] activation and Notch ligand expression in human thymus development. | |||
|date=13.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30042180 | |||
|full-text-url=https://sci-hub.do/10.1242/dev.165597 | |||
}} | |||
==TLR6== | |||
* {{medline-title | |||
|title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149 | |||
}} | |||
==TNP1== | |||
* {{medline-title | |||
|title=Cytological and molecular aspects of the ageing sperm. | |||
|date=01.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142 | |||
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357 | |||
}} | |||
==ACTA2== | |||
* {{medline-title | |||
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325 | |||
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217 | |||
}} | |||
==LGI1== | |||
* {{medline-title | |||
|title=Antibody-associated CNS syndromes without signs of inflammation in the elderly. | |||
|date=03.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28878050 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631166 | |||
}} | |||
==AKT3== | |||
* {{medline-title | |||
|title=Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097674 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135677 | |||
}} | |||
==NKAP== | |||
* {{medline-title | |||
|title=[[NKAP]] Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31632967 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783958 | |||
}} | |||
==FOXP4== | |||
* {{medline-title | |||
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization. | |||
|date=06.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247 | |||
}} | |||
==RPL13== | |||
* {{medline-title | |||
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261 | |||
}} | |||
==NACA== | |||
* {{medline-title | |||
|title=Age and Sex Are Strongly Correlated to the Rate and Type of Mountain Injuries Requiring Search and Rescue Missions. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31699646 | |||
|full-text-url=https://sci-hub.do/10.1016/j.wem.2019.06.016 | |||
}} | |||
==FAM13A== | |||
* {{medline-title | |||
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171 | |||
}} | |||
==FBN2== | |||
* {{medline-title | |||
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging. | |||
|date=26.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848 | |||
}} | |||
==ADRA2A== | |||
* {{medline-title | |||
|title=α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33116632 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574911 | |||
}} | |||
==HPSE== | |||
* {{medline-title | |||
|title=Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin. | |||
|date=07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32159248 | |||
|full-text-url=https://sci-hub.do/10.1002/cbin.11339 | |||
}} | |||
==QRFPR== | |||
* {{medline-title | |||
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019 | |||
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6 | |||
}} | |||
==MCM8== | |||
* {{medline-title | |||
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184 | |||
}} | |||
==LGR6== | |||
* {{medline-title | |||
|title=Effect of defensins-containing eye cream on periocular rhytids and skin quality. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32614135 | |||
|full-text-url=https://sci-hub.do/10.1111/jocd.13424 | |||
}} | |||
==NLRP12== | |||
* {{medline-title | |||
|title=Persistent DNA damage-induced [[NLRP12]] improves hematopoietic stem cell function. | |||
|date=21.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434992 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259522 | |||
}} | |||
==DAPK2== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
==HLA-DQA1== | |||
* {{medline-title | |||
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488 | |||
}} | |||
==COL13A1== | |||
* {{medline-title | |||
|title=[Alu insertion-deletion polymorphism of [[COL13A1]] and [[LAMA2]] genes: The analysis of association with longevity]. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369589 | |||
}} | |||
==CABLES1== | |||
* {{medline-title | |||
|title=[[CABLES1]] Deficiency Impairs Quiescence and Stress Responses of Hematopoietic Stem Cells in Intrinsic and Extrinsic Manners. | |||
|date=13.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327733 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700604 | |||
}} | |||
==CCND2== | |||
* {{medline-title | |||
|title=Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097674 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135677 | |||
}} | |||
==CD226== | |||
* {{medline-title | |||
|title=T-cell Immunoglobulin and ITIM Domain Contributes to CD8 T-cell Immunosenescence. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29349889 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847879 | |||
}} | |||
==ACAD10== | |||
* {{medline-title | |||
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157 | |||
|full-text-url=https://sci-hub.do/10.1111/jbg.12299 | |||
}} | |||
==DSPP== | |||
* {{medline-title | |||
|title=Effects of [i]p[/i]-Cresol on Senescence, Survival, Inflammation, and Odontoblast Differentiation in Canine Dental Pulp Stem Cells. | |||
|date=21.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32967298 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555360 | |||
}} | |||
==POLR3A== | |||
* {{medline-title | |||
|title=Nucleolar disruption, activation of P53 and premature senescence in [[POLR3A]]-mutated Wiedemann-Rautenstrauch syndrome fibroblasts. | |||
|date=12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32976914 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111360 | |||
}} | |||
==RCAN1== | |||
* {{medline-title | |||
|title=Mitochondrial dysfunction and endoplasmic reticulum stress involved in oocyte aging: an analysis using single-cell RNA-sequencing of mouse oocytes. | |||
|date=08.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31176373 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556043 | |||
}} | |||
==PCCA== | |||
* {{medline-title | |||
|title=Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29159707 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832583 | |||
}} | |||
==GABARAP== | |||
* {{medline-title | |||
|title=Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. | |||
|date=18.08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32811819 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434891 | |||
}} | |||
==TIMP2== | |||
* {{medline-title | |||
|title=The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30252623 | |||
|full-text-url=https://sci-hub.do/10.1080/09537104.2018.1514110 | |||
}} | |||
==DSCAM== | |||
* {{medline-title | |||
|title=Age- and speed-dependent modulation of gaits in [[DSCAM]] mutant mice. | |||
|date=01.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29093169 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867377 | |||
}} | |||
==SESN3== | |||
* {{medline-title | |||
|title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging. | |||
|date=25.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052 | |||
}} | |||
==GPR6== | |||
* {{medline-title | |||
|title=Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy. | |||
|date=22.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32959881 | |||
|full-text-url=https://sci-hub.do/10.1093/infdis/jiaa599 | |||
}} | |||
==NR3C1== | |||
* {{medline-title | |||
|title=Glucocorticoid receptor ([[NR3C1]]) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30553025 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.12.006 | |||
}} | |||
==CHSY1== | |||
* {{medline-title | |||
|title=Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in [i]skt[/i] Mice. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754016 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944401 | |||
}} | |||
==RAD50== | |||
* {{medline-title | |||
|title=Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells. | |||
|date=01.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775409 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172637 | |||
}} | |||
==INPP5A== | |||
* {{medline-title | |||
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | |||
|date=25.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | |||
}} | |||
==GREM1== | |||
* {{medline-title | |||
|title=[[GREM1]] inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. | |||
|date=09.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151168 | |||
|full-text-url=https://sci-hub.do/10.1080/03008207.2020.1736054 | |||
}} | |||
==TLR8== | |||
* {{medline-title | |||
|title=[[TLR8]]-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy. | |||
|date=08.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30344014 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050437 | |||
}} | |||
==HSPA13== | |||
* {{medline-title | |||
|title=Genetic associations with age of menopause in familial longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937 | |||
}} | |||
==APOA1== | |||
* {{medline-title | |||
|title=Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29623474 | |||
|full-text-url=https://sci-hub.do/10.1007/s10534-018-0101-y | |||
}} | |||
==MICA== | |||
* {{medline-title | |||
|title=Derivation and Validation of a Geriatric-Sensitive Perioperative Cardiac Risk Index. | |||
|date=16.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146612 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721761 | |||
}} | |||
==HOXC4== | |||
* {{medline-title | |||
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015 | |||
}} | |||
==VAMP2== | |||
* {{medline-title | |||
|title=Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29950309 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068464 | |||
}} | |||
==RTN4== | |||
* {{medline-title | |||
|title=Cell fate regulation by reticulon-4 in human prostate cancers. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.27704 | |||
}} | |||
==SGK1== | |||
* {{medline-title | |||
|title=Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223380 | |||
|full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.120.14642 | |||
}} | |||
==HDAC8== | |||
* {{medline-title | |||
|title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771 | |||
}} | |||
==UMOD== | |||
* {{medline-title | |||
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468 | |||
}} | |||
==DRAM1== | |||
* {{medline-title | |||
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896 | |||
}} | |||
==SELENOH== | |||
* {{medline-title | |||
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511 | |||
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9 | |||
}} | |||
==CASK== | |||
* {{medline-title | |||
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001 | |||
}} | |||
==ARHGAP18== | |||
* {{medline-title | |||
|title=Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma | |||
|date=18.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327185 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863019 | |||
}} | |||
==GSTK1== | |||
* {{medline-title | |||
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | |||
}} | |||
==HOXD8== | |||
* {{medline-title | |||
|title=Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849838 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431633 | |||
}} | |||
==ABL1== | |||
* {{medline-title | |||
|title=European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32127639 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214240 | |||
}} | |||
==TSHR== | |||
* {{medline-title | |||
|title=TSH-independent release of thyroid hormones through cold exposure in aging rats. | |||
|date=27.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163760 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685681 | |||
}} | |||
==AACS== | |||
* {{medline-title | |||
|title=Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study. | |||
|date=07.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33170149 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695390 | |||
}} | |||
==POU3F2== | |||
* {{medline-title | |||
|title=[[POU3F2]] participates in cognitive function and adult hippocampal neurogenesis via mammalian-characteristic amino acid repeats. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782255 | |||
|full-text-url=https://sci-hub.do/10.1111/gbb.12408 | |||
}} | |||
==SMC4== | |||
* {{medline-title | |||
|title=The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence. | |||
|date=10.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336977 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.065 | |||
}} | |||
==VCP== | |||
* {{medline-title | |||
|title=The role of air pollution and lung function in cognitive impairment. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467204 | |||
|full-text-url=https://sci-hub.do/10.1183/13993003.01963-2017 | |||
}} | |||
==ADCK1== | |||
* {{medline-title | |||
|title=Functional analysis of Aarf domain-containing kinase 1 in Drosophila melanogaster. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175694 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271681 | |||
}} | |||
==MPL== | |||
* {{medline-title | |||
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454 | |||
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0 | |||
}} | |||
==NOBOX== | |||
* {{medline-title | |||
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. | |||
|date=18.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463 | |||
}} | |||
==MUL1== | |||
* {{medline-title | |||
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models. | |||
|date=28.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415 | |||
}} | |||
==HRG== | |||
* {{medline-title | |||
|title=Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29021712 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628339 | |||
}} | |||
==ADK== | |||
* {{medline-title | |||
|title=Deletion of pancreatic β-cell adenosine kinase improves glucose homeostasis in young mice and ameliorates streptozotocin-induced hyperglycaemia. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044530 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584724 | |||
}} | |||
==SPON1== | |||
* {{medline-title | |||
|title=[[APOE]] influences working memory in non-demented elderly through an interaction with [[SPON1]] rs2618516. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573041 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866309 | |||
}} | |||
==EPG5== | |||
* {{medline-title | |||
|title=Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882010 | |||
}} | |||
==SLC39A6== | |||
* {{medline-title | |||
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. | |||
|date=01.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006 | |||
}} | |||
==SLC22A14== | |||
* {{medline-title | |||
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019 | |||
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6 | |||
}} | |||
==DLL1== | |||
* {{medline-title | |||
|title=MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting [[DLL1]] and Regulating PI3K/AKT Pathway. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048987 | |||
|full-text-url=https://sci-hub.do/10.1159/000492090 | |||
}} | |||
==HOXA3== | |||
* {{medline-title | |||
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | |||
|date=25.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | |||
}} | |||
==OCLN== | |||
* {{medline-title | |||
|title=Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats. | |||
|date=17.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242723 | |||
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b02567 | |||
}} | |||
==DTL== | |||
* {{medline-title | |||
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578 | |||
}} | |||
==SENP6== | |||
* {{medline-title | |||
|title=Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32827359 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576240 | |||
}} | |||
==GHSR== | |||
* {{medline-title | |||
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073 | |||
}} | |||
==SRD5A2== | |||
* {{medline-title | |||
|title=Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32125089 | |||
|full-text-url=https://sci-hub.do/10.1111/jocd.13355 | |||
}} | |||
==KIF1A== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
==GSTT2== | |||
* {{medline-title | |||
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | |||
}} | |||
==HOXA4== | |||
* {{medline-title | |||
|title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529 | |||
}} | |||
==SOX4== | |||
* {{medline-title | |||
|title=Age-induced accumulation of methylmalonic acid promotes tumour progression. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32814897 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2630-0 | |||
}} | |||
==DAZL== | |||
* {{medline-title | |||
|title=[[DAZL]] Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions. | |||
|date=30.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380414 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878787 | |||
}} | |||
==RBM25== | |||
* {{medline-title | |||
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif. | |||
|date=29.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004 | |||
}} | |||
==VEGFA== | |||
* {{medline-title | |||
|title=APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31791659 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064375 | |||
}} | |||
==SRSF1== | |||
* {{medline-title | |||
|title=Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037605 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2018.06.029 | |||
}} | |||
==MYO1F== | |||
* {{medline-title | |||
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788 | |||
}} | |||
==CXCL13== | |||
* {{medline-title | |||
|title=RNA-seq data from C-X-C chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32642521 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334305 | |||
}} | |||
==SURF1== | |||
* {{medline-title | |||
|title=Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696791 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052393 | |||
}} | |||
==MUC7== | |||
* {{medline-title | |||
|title=Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model. | |||
|date=24.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31554163 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835954 | |||
}} | |||
==DHRS2== | |||
* {{medline-title | |||
|title=Acute [[HSF1]] depletion induces cellular senescence through the [[MDM2]]-p53-p21 pathway in human diploid fibroblasts. | |||
|date=08.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632240 | |||
|full-text-url=https://sci-hub.do/10.1242/jcs.210724 | |||
}} | |||
==RPL4== | |||
* {{medline-title | |||
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 | |||
}} | |||
==BMP6== | |||
* {{medline-title | |||
|title=Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology. | |||
|date=06.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352848 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233090 | |||
}} | |||
==ABI3BP== | |||
* {{medline-title | |||
|title=Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing [[ABI3BP]] in gallbladder cancer cells. | |||
|date=07.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174563 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555920 | |||
}} | |||
==AIF1== | |||
* {{medline-title | |||
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062 | |||
}} | |||
==USP30== | |||
* {{medline-title | |||
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i]. | |||
|date=29.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047 | |||
}} | |||
==SPHK2== | |||
* {{medline-title | |||
|title=Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30886000 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446199 | |||
}} | |||
==ITGAM== | |||
* {{medline-title | |||
|title=Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31732940 | |||
|full-text-url=https://sci-hub.do/10.1007/978-3-030-28524-1_11 | |||
}} | |||
==PRR9== | |||
* {{medline-title | |||
|title=Circadian control of [i]ORE1[/i] by [[PRR9]] positively regulates leaf senescence in [i]Arabidopsis[/i]. | |||
|date=14.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30065116 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099856 | |||
}} | |||
==PIK3R2== | |||
* {{medline-title | |||
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014 | |||
}} | |||
==MAVS== | |||
* {{medline-title | |||
|title=Spontaneous activation of a [[MAVS]]-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822807 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600710 | |||
}} | |||
==FNTA== | |||
* {{medline-title | |||
|title=The Hip Morphology Changes with Ageing in Asian Population. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30363710 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180959 | |||
}} | |||
==PRDM1== | |||
* {{medline-title | |||
|title=Age-related changes in the [[BACH2]] and [[PRDM1]] genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients. | |||
|date=17.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654767 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337793 | |||
}} | |||
==ADAR== | |||
* {{medline-title | |||
|title=Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29986212 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037660 | |||
}} | |||
==CD55== | |||
* {{medline-title | |||
|title=Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429373 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303009 | |||
}} | |||
==HMGA1== | |||
* {{medline-title | |||
|title=Characterization of [i][[HMGA1]]P6[/i] transgenic mouse embryonic fibroblasts. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32787507 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513866 | |||
}} | |||
==IL6ST== | |||
* {{medline-title | |||
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014 | |||
}} | |||
==MMP14== | |||
* {{medline-title | |||
|title=Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344220 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755030 | |||
}} | |||
==ANPEP== | |||
* {{medline-title | |||
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity. | |||
|date=25.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174 | |||
}} | |||
==CAV1== | |||
* {{medline-title | |||
|title=Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine. | |||
|date=24.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30690072 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jep.2019.01.019 | |||
}} | |||
==RIPK2== | |||
* {{medline-title | |||
|title=RIP kinases as modulators of inflammation and immunity. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615 | |||
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x | |||
}} | |||
==MAPK8== | |||
* {{medline-title | |||
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 | |||
}} | |||
==GJC2== | |||
* {{medline-title | |||
|title=Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32629311 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.04.017 | |||
}} | |||
==OSGEP== | |||
* {{medline-title | |||
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. | |||
|date=11.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604 | |||
}} | |||
==KIFC3== | |||
* {{medline-title | |||
|title=Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29845728 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052466 | |||
}} | |||
==BMPR2== | |||
* {{medline-title | |||
|title=Centenarians Overexpress Pluripotency-Related Genes. | |||
|date=16.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168 | |||
}} | |||
==RGS2== | |||
* {{medline-title | |||
|title=Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone. | |||
|date=01.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31043680 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494869 | |||
}} | |||
==KRT18== | |||
* {{medline-title | |||
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004 | |||
}} | |||
==IL15== | |||
* {{medline-title | |||
|title=Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of [[IL15]]. | |||
|date=27.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32221610 | |||
|full-text-url=https://sci-hub.do/10.1093/ageing/afaa035 | |||
}} | |||
==PRKG1== | |||
* {{medline-title | |||
|title=Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis. | |||
|date=15.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660387 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.04.007 | |||
}} | |||
==GDF5== | |||
* {{medline-title | |||
|title=An embryonic CaVβ1 isoform promotes muscle mass maintenance via [[GDF5]] signaling in adult mouse. | |||
|date=06.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31694926 | |||
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aaw1131 | |||
}} | |||
==SLC15A1== | |||
* {{medline-title | |||
|title=Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019300 | |||
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3413-x | |||
}} | |||
==WAS== | |||
* {{medline-title | |||
|title=Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number. | |||
|date=09.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129830 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723686 | |||
}} | |||
==VPS13C== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
==EPHA1== | |||
* {{medline-title | |||
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort. | |||
|date=16.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723 | |||
}} | |||
==CDO1== | |||
* {{medline-title | |||
|title=The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway. | |||
|date=19.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131986 | |||
|full-text-url=https://sci-hub.do/10.1039/c8fo00740c | |||
}} | |||
==WDR5== | |||
* {{medline-title | |||
|title=Inhibition of the H3K4 methyltransferase MLL1/[[WDR5]] complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16 . | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570196 | |||
|full-text-url=https://sci-hub.do/10.1016/j.kint.2019.06.021 | |||
}} | |||
==SHD== | |||
* {{medline-title | |||
|title=Does self-reported hearing difficulty decrease older adults' cognitive and physical functioning? The mediating role of social isolation. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33036703 | |||
|full-text-url=https://sci-hub.do/10.1016/j.maturitas.2020.06.011 | |||
}} | |||
==SEMA6C== | |||
* {{medline-title | |||
|title=Suppression of [[SEMA6C]] promotes preantral follicles atresia with decreased cell junctions in mice ovaries. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30256425 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.27294 | |||
}} | |||
==TCF21== | |||
* {{medline-title | |||
|title=Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3. | |||
|date=22.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29748384 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016453 | |||
}} | |||
==USP14== | |||
* {{medline-title | |||
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205 | |||
}} | |||
==MS4A4E== | |||
* {{medline-title | |||
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. | |||
|date=28.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389 | |||
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049 | |||
}} | |||
==PIM1== | |||
* {{medline-title | |||
|title=[[PIM1]]-catalyzed [[CBX8]] phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast. | |||
|date=27.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29763603 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.05.070 | |||
}} | |||
==CHAT== | |||
* {{medline-title | |||
|title=Satisfaction and Technology Evaluation of a Telehealth Robotic Program to Optimize Healthy Independent Living for Older Adults. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320967 | |||
|full-text-url=https://sci-hub.do/10.1111/jnu.12436 | |||
}} | |||
==EIF2B5== | |||
* {{medline-title | |||
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 | |||
}} | |||
==RAD9A== | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
==TRPS1== | |||
* {{medline-title | |||
|title=miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074095 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.28862 | |||
}} | |||
==RIF1== | |||
* {{medline-title | |||
|title=53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. | |||
|date=02.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653568 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993210 | |||
}} | |||
==DAP== | |||
* {{medline-title | |||
|title=Examining changes in the equity of physician distribution in Japan: a specialty-specific longitudinal study. | |||
|date=08.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29317415 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781009 | |||
}} | |||
==GATA6== | |||
* {{medline-title | |||
|title=GATA Regulation and Function During the Ovarian Life Cycle. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544631 | |||
|full-text-url=https://sci-hub.do/10.1016/bs.vh.2018.01.014 | |||
}} | |||
==DUT== | |||
* {{medline-title | |||
|title=Simultaneous liquefaction, saccharification, and fermentation of L-lactic acid using aging paddy rice with hull by an isolated thermotolerant Enterococcus faecalis [[DUT]]1805. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32388689 | |||
|full-text-url=https://sci-hub.do/10.1007/s00449-020-02364-y | |||
}} | |||
==ANXA1== | |||
* {{medline-title | |||
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging. | |||
|date=26.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848 | |||
}} | |||
==ADORA2B== | |||
* {{medline-title | |||
|title=Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss. | |||
|date=12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33131093 | |||
|full-text-url=https://sci-hub.do/10.1096/fj.202000939R | |||
}} | |||
==LAMA5== | |||
* {{medline-title | |||
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. | |||
|date=05.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244 | |||
}} | |||
==LYG1== | |||
* {{medline-title | |||
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171 | |||
}} | |||
==TET3== | |||
* {{medline-title | |||
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493 | |||
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y | |||
}} | |||
==MARCKS== | |||
* {{medline-title | |||
|title=Ser46-Phosphorylated [[MARCKS]] Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. | |||
|date=07-08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225354 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140116 | |||
}} | |||
==PIK3R1== | |||
* {{medline-title | |||
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. | |||
|date=08.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033 | |||
}} | |||
==GJA8== | |||
* {{medline-title | |||
|title=The impact of [[GJA8]] SNPs on susceptibility to age-related cataract. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30349978 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267713 | |||
}} | |||
==CHRNA7== | |||
* {{medline-title | |||
|title=Associations between genetic variations and global motion perception. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31432227 | |||
|full-text-url=https://sci-hub.do/10.1007/s00221-019-05627-7 | |||
}} | |||
==LDB2== | |||
* {{medline-title | |||
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015 | |||
}} | |||
==WNT3== | |||
* {{medline-title | |||
|title=Role of CD133 Molecule in Wnt Response and Renal Repair. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29431914 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827750 | |||
}} | |||
==CDX2== | |||
* {{medline-title | |||
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. | |||
|date=08.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209 | |||
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054 | |||
}} | |||
==RIMS2== | |||
* {{medline-title | |||
|title=Age-related gene and miRNA expression changes in airways of healthy individuals. | |||
|date=06.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842487 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403379 | |||
}} | |||
==P4HA2== | |||
* {{medline-title | |||
|title=Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients. | |||
|date=03.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31560770 | |||
|full-text-url=https://sci-hub.do/10.1167/iovs.19-27921 | |||
}} | |||
==SLC30A10== | |||
* {{medline-title | |||
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. | |||
|date=01.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006 | |||
}} | |||
==ERAP1== | |||
* {{medline-title | |||
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | |||
}} | |||
==SLC30A5== | |||
* {{medline-title | |||
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. | |||
|date=01.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006 | |||
}} | |||
==PTPRC== | |||
* {{medline-title | |||
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456 | |||
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341 | |||
}} | |||
==NPW== | |||
* {{medline-title | |||
|title=Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32309980 | |||
|full-text-url=https://sci-hub.do/10.1037/pag0000468 | |||
}} | |||
==NLRP6== | |||
* {{medline-title | |||
|title=LRP6 targeting suppresses gastric tumorigenesis via P14 -Mdm2-P53-dependent cellular senescence. | |||
|date=19.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29340077 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762345 | |||
}} | |||
==SCNN1B== | |||
* {{medline-title | |||
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. | |||
|date=18.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100 | |||
}} | |||
==SP2== | |||
* {{medline-title | |||
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483 | |||
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0 | |||
}} | |||
==SESN1== | |||
* {{medline-title | |||
|title=Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751091 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.006 | |||
}} | |||
==ISG15== | |||
* {{medline-title | |||
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood. | |||
|date=14.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791 | |||
}} | |||
==RAG2== | |||
* {{medline-title | |||
|title=Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793218 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387685 | |||
}} | |||
==ECM1== | |||
* {{medline-title | |||
|title=Novel role of extracellular matrix protein 1 ([[ECM1]]) in cardiac aging and myocardial infarction. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789914 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383988 | |||
}} | |||
==ROS1== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
==TAF7L== | |||
* {{medline-title | |||
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis. | |||
|date=22.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986 | |||
}} | |||
==TCERG1== | |||
* {{medline-title | |||
|title=The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity. | |||
|date=17.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31316054 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637209 | |||
}} | |||
==RPIA== | |||
* {{medline-title | |||
|title=Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming. | |||
|date=20.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31433975 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716532 | |||
}} | |||
==ACO1== | |||
* {{medline-title | |||
|title=Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine. | |||
|date=24.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30690072 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jep.2019.01.019 | |||
}} | |||
==HLA-DRB1== | |||
* {{medline-title | |||
|title=The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32942037 | |||
|full-text-url=https://sci-hub.do/10.1016/j.autrev.2020.102670 | |||
}} | |||
==LOXL1== | |||
* {{medline-title | |||
|title=A blackberry-dill extract combination synergistically increases skin elasticity. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32583541 | |||
|full-text-url=https://sci-hub.do/10.1111/ics.12644 | |||
}} | |||
==CYP11B2== | |||
* {{medline-title | |||
|title=Expression of aldosterone synthase [[CYP11B2]] was inversely correlated with longevity. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30974191 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786771 | |||
}} | |||
==CDH2== | |||
* {{medline-title | |||
|title=CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type. | |||
|date=30.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102368 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265269 | |||
}} | |||
==STX17== | |||
* {{medline-title | |||
|title=Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and [[XIAP]]. | |||
|date=01.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.05.017 | |||
}} | |||
==CNTNAP2== | |||
* {{medline-title | |||
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456 | |||
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341 | |||
}} | |||
==RGS14== | |||
* {{medline-title | |||
|title=Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29654651 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052469 | |||
}} | |||
==RHEBL1== | |||
* {{medline-title | |||
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551 | |||
}} | |||
==FCER1G== | |||
* {{medline-title | |||
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788 | |||
}} | |||
==PMS1== | |||
* {{medline-title | |||
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. | |||
|date=25.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.28417 | |||
}} | |||
==TXNRD1== | |||
* {{medline-title | |||
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073 | |||
}} | |||
==ITPR2== | |||
* {{medline-title | |||
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923 | |||
}} | |||
==KAT6B== | |||
* {{medline-title | |||
|title=Aging-associated decrease in the histone acetyltransferase [[KAT6B]] is linked to altered hematopoietic stem cell differentiation. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32014431 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179256 | |||
}} | |||
==ASB3== | |||
* {{medline-title | |||
|title=Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585438 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818258 | |||
}} | |||
==F12== | |||
* {{medline-title | |||
|title=Multigenerational effects of carbendazim in Daphnia magna: From a subcellular to a population level. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30508263 | |||
|full-text-url=https://sci-hub.do/10.1002/etc.4307 | |||
}} | |||
==MAL== | |||
* {{medline-title | |||
|title=Daylight photodynamic therapy versus cryosurgery for the treatment and prophylaxis of actinic keratoses of the face - protocol of a multicenter, prospective, randomized, controlled, two-armed study. | |||
|date=25.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29070025 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657041 | |||
}} | |||
==CEBPB== | |||
* {{medline-title | |||
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201 | |||
}} | |||
==UNG== | |||
* {{medline-title | |||
|title=[[UNG]]-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans. | |||
|date=01.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717169 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931555 | |||
}} | |||
==PHB2== | |||
* {{medline-title | |||
|title=Prohibitin-2 is a novel regulator of p21 induced by depletion of γ-glutamylcyclotransferase. | |||
|date=29.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29307834 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.029 | |||
}} | |||
==DBT== | |||
* {{medline-title | |||
|title=Diurnal rhythms of heart and respiratory rates in donkeys of different age groups during the cold-dry and hot-dry seasons in a tropical savannah. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187687 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125241 | |||
}} | |||
==SUGCT== | |||
* {{medline-title | |||
|title=Knockout of the non-essential gene [[SUGCT]] creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31722069 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426296 | |||
}} | |||
==HK2== | |||
* {{medline-title | |||
|title=Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury. | |||
|date=11.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326403 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811244 | |||
}} | |||
==ATP1A2== | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
==ITGA6== | |||
* {{medline-title | |||
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456 | |||
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341 | |||
}} | |||
==EDF1== | |||
* {{medline-title | |||
|title=Silencing of FOREVER YOUNG FLOWER Like Genes from Phalaenopsis Orchids Promotes Flower Senescence and Abscission. | |||
|date=25.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33237274 | |||
|full-text-url=https://sci-hub.do/10.1093/pcp/pcaa145 | |||
}} | |||
==DOT1L== | |||
* {{medline-title | |||
|title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018 | |||
}} | |||
==DAXX== | |||
* {{medline-title | |||
|title=[[ATRX]]-[[DAXX]] Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31361513 | |||
|full-text-url=https://sci-hub.do/10.1089/dna.2019.4752 | |||
}} | |||
==GLO1== | |||
* {{medline-title | |||
|title=The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29259621 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723304 | |||
}} | |||
==S100A6== | |||
* {{medline-title | |||
|title=Sex differences in distribution of cannabinoid receptors (CB1 and CB2), [[S100A6]] and CacyBP/SIP in human ageing hearts. | |||
|date=27.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30482253 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258148 | |||
}} | |||
==PGM1== | |||
* {{medline-title | |||
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. | |||
|date=15.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004 | |||
}} | |||
==TARDBP== | |||
* {{medline-title | |||
|title=Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577934 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ajpath.2018.03.002 | |||
}} | |||
==ANKS1B== | |||
* {{medline-title | |||
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019 | |||
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6 | |||
}} | |||
==DNM1== | |||
* {{medline-title | |||
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363 | |||
}} | |||
==LYST== | |||
* {{medline-title | |||
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort. | |||
|date=16.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723 | |||
}} | |||
==GFRAL== | |||
* {{medline-title | |||
|title=Growth differentiation factor 15 ([[GDF15]]): A survival protein with therapeutic potential in metabolic diseases. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790643 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196666 | |||
}} | |||
==UHRF1== | |||
* {{medline-title | |||
|title=MLL3 promotes the senescence of esophageal squamous cell carcinoma. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30881012 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402438 | |||
}} | |||
==COQ9== | |||
* {{medline-title | |||
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. | |||
|date=18.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522 | |||
}} | |||
==SLC52A2== | |||
* {{medline-title | |||
|title=Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. | |||
|date=01.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053833 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808726 | |||
}} | |||
==PRDM8== | |||
* {{medline-title | |||
|title=[[PRDM8]] reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation. | |||
|date=20.08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32819411 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439574 | |||
}} | |||
==F10== | |||
* {{medline-title | |||
|title=Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-[[F10]] cells by inducing senescence. | |||
|date=15.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097108 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.06.008 | |||
}} | |||
==DNM2== | |||
* {{medline-title | |||
|title=Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy. | |||
|date=19.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451843 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243013 | |||
}} | |||
==PSAP== | |||
* {{medline-title | |||
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342 | |||
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9 | |||
}} | |||
==TRIM21== | |||
* {{medline-title | |||
|title=[[TRIM21]] overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32064156 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017742 | |||
}} | |||
==TMEM119== | |||
* {{medline-title | |||
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z | |||
}} | |||
==CDC6== | |||
* {{medline-title | |||
|title=A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence. | |||
|date=10.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29321003 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763532 | |||
}} | |||
==RPL11== | |||
* {{medline-title | |||
|title=[[NOL12]] Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging. | |||
|date=15.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988155 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549468 | |||
}} | |||
==EED== | |||
* {{medline-title | |||
|title=Economic evaluations of eHealth technologies: A systematic review. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897921 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999277 | |||
}} | |||
==PAX1== | |||
* {{medline-title | |||
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. | |||
|date=26.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307 | |||
}} | |||
==FER1L6== | |||
* {{medline-title | |||
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157 | |||
|full-text-url=https://sci-hub.do/10.1111/jbg.12299 | |||
}} | |||
==KDM5A== | |||
* {{medline-title | |||
|title=Structure-Based Discovery of a Selective [[KDM5A]] Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines. | |||
|date=15.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30650517 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360022 | |||
}} | |||
==CYP11B1== | |||
* {{medline-title | |||
|title=Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002589 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105764 | |||
}} | |||
==ALAS1== | |||
* {{medline-title | |||
|title=Heterozygous disruption of [[ALAS1]] in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver. | |||
|date=08.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33307066 | |||
|full-text-url=https://sci-hub.do/10.1016/j.abb.2020.108721 | |||
}} | |||
==TRAP1== | |||
* {{medline-title | |||
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 | |||
}} | |||
==ASIP== | |||
* {{medline-title | |||
|title=Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222197 | |||
|full-text-url=https://sci-hub.do/10.1111/ics.12494 | |||
}} | |||
==MSH2== | |||
* {{medline-title | |||
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. | |||
|date=25.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.28417 | |||
}} | |||
==SMC3== | |||
* {{medline-title | |||
|title=Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667147 | |||
|full-text-url=https://sci-hub.do/10.1007/s11655-018-2835-3 | |||
}} | |||
==RNF168== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair. | ||
|date= | |date=06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001 | ||
}} | }} |
Версия от 14:30, 31 марта 2021
- Genes with 100 and more publications
- Genes with 60-99 publications
- Genes with 30-59 publications
- Genes with 10-29 publications
- Genes with 3-9 publications
- Genes with 1-2 publications
SOCS1
- Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. / 06.2019 / PubMed / Full text
- SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes. / 28.10.2017 / PubMed / Full text
ATG9A
- SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy. / 08.2019 / PubMed / Full text
- Activation of miR-34a impairs autophagic flux and promotes cochlear cell death via repressing ATG9A: implications for age-related hearing loss. / 05.10.2017 / PubMed / Full text
LAT2
- Blood glucose, amino acid profiles and nutrient transporter gene expressions in the small intestine of low and normal birthweight piglets during the early suckling period. / 05.2019 / PubMed / Full text
- Skeletal muscle: from birth to old age, routes to mechanical and metabolic failure. / 2017 / PubMed / Full text
ID1
- Commentary on Some Recent Theses Relevant to Combating Aging: April 2019. / 04.2019 / PubMed / Full text
- ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras. / 12.09.2017 / PubMed / Full text
OAT
- Opioid agonist treatment reduces losses in quality of life and quality-adjusted life expectancy in heroin users: Evidence from real world data. / 01.08.2019 / PubMed / Full text
- Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats. / 02.2019 / PubMed / Full text
ERBB2
- The biological age linked to oxidative stress modifies breast cancer aggressiveness. / 20.05.2018 / PubMed / Full text
- Identification of human age-associated gene co-expressions in functional modules using liquid association. / 02.01.2018 / PubMed / Full text
NDNF
- Effect of neuron-derived neurotrophic factor on rejuvenation of human adipose-derived stem cells for cardiac repair after myocardial infarction. / 09.2019 / PubMed / Full text
- Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury. / 12.2017 / PubMed / Full text
NECTIN2
- Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text
- Apolipoprotein E region molecular signatures of Alzheimer's disease. / 08.2018 / PubMed / Full text
NDUFB8
- Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. / 23.05.2018 / PubMed / Full text
- Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions. / 06.2018 / PubMed / Full text
HSF2
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
- Nutrition and water temperature regulate the expression of heat-shock proteins in golden pompano larvae (Trachinotus ovata, Limmaeus 1758). / 04.2019 / PubMed / Full text
IQGAP1
- IQGAP1-dysfunction leads to induction of senescence in human vascular smooth muscle cells. / 09.2020 / PubMed / Full text
- Hyaluronan-binding protein 1 (HABP1) overexpression triggers induction of senescence in fibroblasts cells. / 06.2020 / PubMed / Full text
PAK1
- 1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating PAK1 at nM levels. / 2018 / PubMed / Full text
- From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic PAK1-blockers/longevity-promoters for cancer therapy. / 15.12.2017 / PubMed / Full text
GNRH1
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
- Elucidating the genetic architecture of reproductive ageing in the Japanese population. / 17.05.2018 / PubMed / Full text
SORL1
- A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study. / 05.2019 / PubMed / Full text
- Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age. / 2018 / PubMed / Full text
CISD2
- CISD2 Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells-As a Potential Therapeutic Target for Neurodegenerative Dementia. / 2020 / PubMed / Full text
- Protective Effects of CISD2 and Influence of Curcumin on CISD2 Expression in Aged Animals and Inflammatory Cell Model. / 25.03.2019 / PubMed / Full text
MAPKAPK2
- Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. / 03.12.2019 / PubMed / Full text
- Cell fate regulation by reticulon-4 in human prostate cancers. / 07.2019 / PubMed / Full text
RPS6
- Regulation of Amino Acid Transporters and Sensors in Response to a High protein Diet: A Randomized Controlled Trial in Elderly Men. / 2019 / PubMed / Full text
- Endothelial replicative senescence delayed by the inhibition of MTORC1 signaling involves MicroRNA-107. / 08.2018 / PubMed / Full text
NNMT
- Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle. / 05.2019 / PubMed / Full text
- Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy. / 09.2018 / PubMed / Full text
SPARCL1
- Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment. / 18.06.2019 / PubMed / Full text
- SPARCL1 Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging. / 2018 / PubMed / Full text
IRF7
- Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood. / 14.01.2019 / PubMed / Full text
- Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text
RGN
- Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04. / 2018 / PubMed / Full text
- Effect of supplementation of recombinant Regucalcin in extender on cryopreservation of spermatozoa of water buffalo (Bubalus bubalis). / 11.2017 / PubMed / Full text
MCM7
- Changes in MCM2-7 proteins at senescence. / 27.07.2019 / PubMed / Full text
- Inhibition of CIP2A attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma. / 08.01.2018 / PubMed / Full text
AQP1
- Blue Light Induces Down-Regulation of Aquaporin 1, 3, and 9 in Human Keratinocytes. / 03.11.2018 / PubMed / Full text
- [Age-related changes of water transport by corneal endothelial cells in rats.] / 2017 / PubMed
EN1
- Electrochemically detecting DNA methylation in the EN1 gene promoter: implications for understanding ageing and disease. / 27.11.2020 / PubMed / Full text
- The role of DNA methylation in ageing and cancer. / 11.2018 / PubMed / Full text
PPID
- Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population. / 03.2020 / PubMed / Full text
- Epidemiology of pituitary pars intermedia dysfunction: A systematic literature review of clinical presentation, disease prevalence and risk factors. / 05.2018 / PubMed / Full text
ADH5
- Can Serum Nitrosoproteome Predict Longevity of Aged Women? / 27.11.2020 / PubMed / Full text
- Denitrosylate and live longer: how ADH5/GSNOR links mitophagy to aging. / 2018 / PubMed / Full text
LTB
- Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA + DHA. / 06.2019 / PubMed / Full text
- Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis. / 11.2017 / PubMed / Full text
TRH
- Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats. / 15.03.2018 / PubMed / Full text
- Effect of dietary carbohydrates and time of year on ACTH and cortisol concentrations in adult and aged horses. / 04.2018 / PubMed / Full text
GLS
- Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography. / 15.07.2018 / PubMed / Full text
- Future Perspectives for Management of Stage A Heart Failure. / 01.07.2018 / PubMed / Full text
CLC
- Impact of Intervention to Improve Nursing Home Resident-Staff Interactions and Engagement. / 13.07.2018 / PubMed / Full text
- Effect of cholesterol loaded cyclodextrin on semen cryopreservation of Aksaray Malakli shepherd dogs of different ages. / 06.2018 / PubMed / Full text
RAG1
- T cell senescence accelerates Angiotensin II-induced target organ damage. / 12.02.2020 / PubMed / Full text
- Aged murine hematopoietic stem cells drive aging-associated immune remodeling. / 09.08.2018 / PubMed / Full text
HLA-C
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
- Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. / 2017 / PubMed / Full text
WFS1
- Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila. / 01.2018 / PubMed / Full text
- A nonsynonymous mutation in the WFS1 gene in a Finnish family with age-related hearing impairment. / 11.2017 / PubMed / Full text
PLIN2
- Cardiac overexpression of perilipin 2 induces atrial steatosis, connexin 43 remodeling, and atrial fibrillation in aged mice. / 01.12.2019 / PubMed / Full text
- HDAC6 Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of PLIN2 in Drosophila. / 09.10.2017 / PubMed / Full text
CCL24
- Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text
- Anserine/Carnosine Supplementation Suppresses the Expression of the Inflammatory Chemokine CCL24 in Peripheral Blood Mononuclear Cells from Elderly People. / 31.10.2017 / PubMed / Full text
TAS2R16
- Taste receptor polymorphisms and longevity: a systematic review and meta-analysis. / 10.11.2020 / PubMed / Full text
- Taste receptors, innate immunity and longevity: the case of TAS2R16 gene. / 2019 / PubMed / Full text
B4GALT1
- Expression of β-1,4-galactosyltransferases during Aging in Caenorhabditis elegans. / 2020 / PubMed / Full text
- Glycobiology of Aging. / 2018 / PubMed / Full text
FGFR4
- FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. / 14.10.2020 / PubMed / Full text
- The Klotho proteins in health and disease. / 01.2019 / PubMed / Full text
NAV2
- Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text
- Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text
ANK1
- Alzheimer's Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in [i]Drosophila[/i]. / 2019 / PubMed / Full text
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
COL3A1
- Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. / 21.12.2019 / PubMed / Full text
- Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts. / 06.2019 / PubMed / Full text
ATP7A
- Adipocyte-specific disruption of ATPase copper transporting α in mice accelerates lipoatrophy. / 12.2019 / PubMed / Full text
- TAp73 regulates ATP7A: possible implications for ageing-related diseases. / 08.12.2018 / PubMed / Full text
TPO
- Megakaryocytes promote osteoclastogenesis in aging. / 07.07.2020 / PubMed / Full text
- To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex-independent) NOD.H2 mice. / 04.2019 / PubMed / Full text
HAS1
- A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text
- Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. / 01.2018 / PubMed / Full text
TIMELESS
- Loss of circadian protein TIMELESS accelerates the progression of cellular senescence. / 18.09.2018 / PubMed / Full text
- Clock gene expression and locomotor activity predict death in the last days of life in Drosophila melanogaster. / 09.08.2018 / PubMed / Full text
PROC
- Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation. / 15.04.2020 / PubMed / Full text
- Effects of feeding frequency of an elevated plane of milk replacer and calf age on behavior, and glucose and insulin kinetics in male Holstein calves. / 07.2019 / PubMed / Full text
FLT1
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
- Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. / 08.10.2018 / PubMed / Full text
IGFBP1
- Role of IGFBP1 in the senescence of vascular endothelial cells and severity of aging‑related coronary atherosclerosis. / 11.2019 / PubMed / Full text
- Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age. / 04.2018 / PubMed / Full text
NLRC4
- Hyperglycemia-induced inflamm-aging accelerates gingival senescence via NLRC4 phosphorylation. / 06.12.2019 / PubMed / Full text
- Contribution of the inflammasome to inflammaging. / 2018 / PubMed / Full text
PTBP1
- Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. / 11.12.2018 / PubMed / Full text
- PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. / 09.07.2018 / PubMed / Full text
LSR
- Age-related changes in regiospecific expression of Lipolysis Stimulated Receptor (LSR) in mice brain. / 2019 / PubMed / Full text
- Discriminating Alzheimer's disease progression using a new hippocampal marker from T1-weighted MRI: The local surface roughness. / 01.04.2019 / PubMed / Full text
MLH1
- The somatic mutation landscape of the human body. / 24.12.2019 / PubMed / Full text
- RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text
DISC1
- Age-Related Changes in Topological Degradation of White Matter Networks and Gene Expression in Chronic Schizophrenia. / 11.2017 / PubMed / Full text
- Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice. / 19.09.2017 / PubMed / Full text
RAN
- Rapid automatized naming (RAN): effects of aging on a predictor of reading skill. / 17.08.2020 / PubMed / Full text
- SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F. / 01.10.2018 / PubMed / Full text
SRR
- Mediterranean diet and its components in relation to all-cause mortality: meta-analysis. / 11.2018 / PubMed / Full text
- Genetic Biomarkers on Age-Related Cognitive Decline. / 2017 / PubMed / Full text
MIF
- Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice. / 09.2019 / PubMed / Full text
- Macrophage migration inhibitory factor knockdown inhibit viability and induce apoptosis of PVM/Ms. / 12.2017 / PubMed / Full text
GSTA4
- Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue. / 02.2019 / PubMed / Full text
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
MCM2
- Trophoblast type-specific expression of senescence markers in the human placenta. / 15.09.2019 / PubMed / Full text
- Changes in MCM2-7 proteins at senescence. / 27.07.2019 / PubMed / Full text
RNF8
- Expression of RNF8 on cochlear apoptosis and aging in mice of different ages. / 03-Apr,.2019 / PubMed
- Function of RAD6B and RNF8 in spermatogenesis. / 2018 / PubMed / Full text
NOTCH3
- Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
AGO2
- Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. / 06.2018 / PubMed / Full text
- miRNA processing gene polymorphisms, blood DNA methylation age and long-term ambient PM exposure in elderly men. / 12.2017 / PubMed / Full text
LATS2
- [Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. / 25.06.2019 / PubMed
- YAP1-LATS2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis. / 03.2019 / PubMed / Full text
CTLA4
- Horticultural Therapy Reduces Biomarkers of Immunosenescence and Inflammaging in Community-Dwelling Older Adults: A Feasibility Pilot Randomized Controlled Trial. / 18.10.2020 / PubMed / Full text
- [Efficacy and toxicity of immune checkpoint inhibitors in elderly patients - 5th edition of the congress of pharmacology of anticancer drugs]. / 12.2018 / PubMed / Full text
SESN2
- Copy Number Alterations in Papillary Thyroid Carcinomas: Does Loss of [i]SESN2[/i] Have a Role in Age-related Different Prognoses? / 09-10.2020 / PubMed / Full text
- Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea. / 11.10.2017 / PubMed / Full text
ZEB1
- MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1. / 12.2018 / PubMed / Full text
- Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating DNMT1 via ZEB1. / 16.02.2018 / PubMed / Full text
CLPP
- Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging. / 02.2019 / PubMed / Full text
- Mitochondrial unfolded protein response gene Clpp is required to maintain ovarian follicular reserve during aging, for oocyte competence, and development of pre-implantation embryos. / 08.2018 / PubMed / Full text
BNIP3
- Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. / 01.10.2019 / PubMed / Full text
- Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training. / 01.10.2018 / PubMed / Full text
CSRP1
- FOXO3, a Molecular Search for the Fountain of Youth. / 07.03.2019 / PubMed / Full text
- FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. / 07.03.2019 / PubMed / Full text
BCL6
- Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation. / 01.07.2020 / PubMed / Full text
- Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text
GRK5
- Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone. / 01.05.2019 / PubMed / Full text
- GRK5 - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders. / 2018 / PubMed / Full text
MCL1
- MCL1 gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway. / 01.2019 / PubMed / Full text
- A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress. / 10.08.2017 / PubMed / Full text
COPE
- Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the COPE-study. / 09.04.2020 / PubMed / Full text
- Falls self-efficacy and falls incidence in community-dwelling older people: the mediating role of coping. / 05.2018 / PubMed / Full text
L1CAM
- Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression. / 12.09.2019 / PubMed / Full text
- Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence. / 28.03.2018 / PubMed / Full text
MMP3
- Systemic analysis of gene expression profiles in porcine granulosa cells during aging. / 14.11.2017 / PubMed / Full text
- Identification of a pyridine derivative inducing senescence in ovarian cancer cell lines via P21 activation. / 05.2018 / PubMed / Full text
INSL3
- Effect of Thyroxine Replacement on Leydig Cell and Sertoli Cell Function in Men with Hypothyroidism. / 05-06.2020 / PubMed / Full text
- Age related and seasonal changes of plasma concentrations of insulin-like peptide 3 and testosterone from birth to early-puberty in Thoroughbred male horses. / 01.07.2019 / PubMed / Full text
CYP1A1
- Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population. / 10.2019 / PubMed / Full text
- Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells. / 15.12.2018 / PubMed / Full text
POSTN
- A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals POSTN As a New Element in Proline Metabolic Disorder. / 12.2018 / PubMed / Full text
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
HLA-B
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
- Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. / 2017 / PubMed / Full text
IRF4
- Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text
- Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice. / 11.2017 / PubMed / Full text
PLD2
- Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. / 08.2019 / PubMed / Full text
- Role of phospholipase D in the lifespan of Caenorhabditis elegans. / 06.04.2018 / PubMed / Full text
IDE
- Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity. / 2020 / PubMed / Full text
- Hyperinsulinemia is associated with increasing insulin secretion but not with decreasing insulin clearance in an age-related metabolic dysfunction mice model. / 06.2019 / PubMed / Full text
NPR1
- The NPR1-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana. / 03.12.2020 / PubMed / Full text
- Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis. / 07.2020 / PubMed / Full text
CYP2D6
- Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. / 05.2019 / PubMed / Full text
- [Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug]. / 2018 / PubMed / Full text
PAPPA
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
- Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text
ZC3H12A
- Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation. / 12.2019 / PubMed / Full text
- Prediction and characterization of human ageing-related proteins by using machine learning. / 06.03.2018 / PubMed / Full text
NMNAT2
- NMNAT2-mediated NAD generation is essential for quality control of aged oocytes. / 06.2019 / PubMed / Full text
- Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy. / 03.10.2017 / PubMed / Full text
BMF
- lncRNA-ES3/miR-34c-5p/BMF axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs. / 17.01.2019 / PubMed / Full text
- Aging, hematopoiesis, and the myelodysplastic syndromes. / 08.12.2017 / PubMed / Full text
ACAT1
- An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. / 06.2019 / PubMed / Full text
- Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. / 15.12.2017 / PubMed / Full text
CYLD
- Premature aging and cancer development in transgenic mice lacking functional CYLD. / 10.01.2019 / PubMed / Full text
- Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis. / 22.01.2019 / PubMed / Full text
POT1
- MiR-185 targets POT1 to induce telomere dysfunction and cellular senescence. / 18.07.2020 / PubMed / Full text
- Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence. / 2019 / PubMed / Full text
CPQ
- A Spanish Adaptation of the Computer and Mobile Device Proficiency Questionnaires (CPQ and MDPQ) for Older Adults. / 2019 / PubMed / Full text
- Protective Effect of Semisynthetic and Natural Flavonoid on Aged Rat Microglia-enriched Cultures. / 11.2019 / PubMed / Full text
NRK
- [Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/ULK1 signaling activation]. / 03.2019 / PubMed / Full text
- Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy. / 24.12.2018 / PubMed / Full text
CCL20
- p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. / 06.2020 / PubMed / Full text
- Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly. / 02.2018 / PubMed / Full text
YAP1
- [Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. / 25.06.2019 / PubMed
- YAP1-LATS2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis. / 03.2019 / PubMed / Full text
CYP1A2
- Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of CYP1A2-Mediated Pharmacokinetics in Young and Elderly Chinese Adults. / 07.2019 / PubMed / Full text
- Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. / 12.2017 / PubMed / Full text
ARID1A
- Oncogenic mutations in histologically normal endometrium: the new normal? / 10.2019 / PubMed / Full text
- ARID1A suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[CDKN2A]] regulatory axis. / 18.11.2017 / PubMed / Full text
CPD
- Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease. / 05.2019 / PubMed / Full text
- What Do Clinical Supervisors Require to Teach Residents in Family Medicine How to Care for Seniors? / 03.2018 / PubMed / Full text
CYP27B1
- Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance. / 01.08.2018 / PubMed / Full text
- Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism. / 22.02.2018 / PubMed / Full text
FHL2
- Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text
- DNA methylation of the ELOVL2, FHL2, KLF14, C1orf132/MIR29B2C, and TRIM59 genes for age prediction from blood, saliva, and buccal swab samples. / 01.2019 / PubMed / Full text
LRP5
- LRP5 in age-related changes in vascular and alveolar morphogenesis in the lung. / 05.01.2019 / PubMed / Full text
- Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand. / 07.11.2018 / PubMed / Full text
CFD
- Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D. / 07.2019 / PubMed / Full text
- New horizons in the compression of functional decline. / 01.11.2018 / PubMed / Full text
CHI3L1
- Postsynaptic damage and microglial activation in AD patients could be linked CXCR4/CXCL12 expression levels. / 15.12.2020 / PubMed / Full text
- Sex difference in CHI3L1 expression levels in human brain aging and in Alzheimer's disease. / 01.10.2019 / PubMed / Full text
FOXA1
- Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer. / 28.09.2019 / PubMed / Full text
- The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. / 05.06.2018 / PubMed / Full text
CCL17
- Aging and chronic high-fat feeding negatively affects kidney size, function, and gene expression in CTRP1-deficient mice. / 21.10.2020 / PubMed / Full text
- Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. / 21.05.2019 / PubMed / Full text
SSB
- Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study. / 03.12.2019 / PubMed / Full text
- WHIRLY1 Occupancy Affects Histone Lysine Modification and [i]WRKY53[/i] Transcription in [i]Arabidopsis[/i] Developmental Manner. / 2018 / PubMed / Full text
HGD
- High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans. / 2019 / PubMed / Full text
- A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of [i]C. elegans[/i]. / 05.10.2018 / PubMed / Full text
SMAD2
- Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation. / 02.2020 / PubMed / Full text
- Restoring extracellular matrix synthesis in senescent stem cells. / 10.2019 / PubMed / Full text
LRP4
- Multiple MuSK signaling pathways and the aging neuromuscular junction. / 13.07.2020 / PubMed / Full text
- Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4. / 10.10.2018 / PubMed / Full text
DDX58
- Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood. / 14.01.2019 / PubMed / Full text
- Age-associated mRNA expression changes in bovine endometrial cells in vitro. / 14.08.2017 / PubMed / Full text
HAL
- Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population. / 06-09.2018 / PubMed / Full text
- Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats. / 06.2019 / PubMed / Full text
FAAH
- Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice. / 02.2020 / PubMed / Full text
- Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. / 05.2019 / PubMed / Full text
FABP4
- Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation. / 05.2018 / PubMed / Full text
- Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects. / 13.09.2017 / PubMed / Full text
TREX1
- Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. / 2019 / PubMed / Full text
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
MAP1LC3B
- The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells. / 01.09.2018 / PubMed / Full text
- Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text
PYY
- Peptide YY (PYY) Is Expressed in Human Skeletal Muscle Tissue and Expanding Human Muscle Progenitor Cells. / 2019 / PubMed / Full text
- Peptide YY induces characteristic meal patterns of aged mice. / 11.2017 / PubMed / Full text
MAPK14
- Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. / 10.2018 / PubMed / Full text
- G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
NCL
- Factors Affecting Microvascular Responses in the Bulbar Conjunctiva in Habitual Contact Lens Wearers. / 01.08.2018 / PubMed / Full text
- Small nucleoli are a cellular hallmark of longevity. / 30.08.2017 / PubMed / Full text
ACACA
- Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
- GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling. / 07.2018 / PubMed / Full text
ATG3
- Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells. / 01.04.2020 / PubMed / Full text
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
AREG
- Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. / 12.2019 / PubMed / Full text
- Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text
PTPN11
- Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array. / 01.10.2020 / PubMed / Full text
- A tyrosine kinase-activating variant Asn666Ser in PDGFRB causes a progeria-like condition in the severe end of Penttinen syndrome. / 04.2019 / PubMed / Full text
NOP10
- Pseudouridylation defect due to [i]DKC1[/i] and [i]NOP10[/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. / 30.06.2020 / PubMed / Full text
- Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. / 04.2018 / PubMed / Full text
MTM1
- Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice. / 20.03.2019 / PubMed / Full text
- Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy. / 19.11.2018 / PubMed / Full text
IDS
- Effect of immediate dentine sealing on the aging and fracture strength of lithium disilicate inlays and overlays. / 10.2020 / PubMed / Full text
- Increased double limb support times during walking in right limb dominant healthy older adults with low bone density. / 06.2018 / PubMed / Full text
SV2A
- Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging. / 01.10.2018 / PubMed / Full text
- Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. / 10.2018 / PubMed / Full text
NMNAT1
- ADNP differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. / 06.2019 / PubMed / Full text
- Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text
VCAM1
- Sunitinib facilitates metastatic breast cancer spreading by inducing endothelial cell senescence. / 29.09.2020 / PubMed / Full text
- Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1. / 06.2019 / PubMed / Full text
NOS2
- Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
- Secreted α-Klotho maintains cartilage tissue homeostasis by repressing [i]NOS2[/i] and [i]ZIP8-MMP13[/i] catabolic axis. / 19.06.2018 / PubMed / Full text
SCAP
- Dementia outcomes after addition of proxy-based assessments for deceased or proxy-dependent participants. / 10.2019 / PubMed / Full text
- Increased hepatic INSIG-SCAP-SREBP expression is associated with cholesterol metabolism disorder in assisted reproductive technology-conceived aged mice. / 03.2019 / PubMed / Full text
AGER
- Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model. / 01.10.2019 / PubMed / Full text
- Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. / 03.2018 / PubMed / Full text
PDC
- The mitochondrial translocase of the inner membrane PaTim54 is involved in defense response and longevity in Podospora anserina. / 11.2019 / PubMed / Full text
- Neuron-specific knockdown of Drosophila PDHB induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting. / 15.05.2018 / PubMed / Full text
SLC25A24
- De Novo Mutations in SLC25A24 Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise. / 02.11.2017 / PubMed / Full text
- De Novo Mutations in SLC25A24 Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction. / 02.11.2017 / PubMed / Full text
DICER1
- DICER1: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging. / 2018 / PubMed / Full text
- Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. / 06.2018 / PubMed / Full text
LDHA
- Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16 inactivation. / 26.02.2018 / PubMed / Full text
- Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming. / 05.2018 / PubMed / Full text
SNCB
- Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. / 08.2019 / PubMed / Full text
- Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro. / 05.2018 / PubMed / Full text
AQP3
- Transbuccal platform for delivery of lipogenic actives to facial skin: Because fat matters. / 08.2020 / PubMed / Full text
- [Age-related changes of water transport by corneal endothelial cells in rats.] / 2017 / PubMed
HRAS
- How do combinations of unhealthy behaviors relate to attitudinal factors and subjective health among the adult population in the Netherlands? / 03.04.2020 / PubMed / Full text
- Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype. / 07.02.2020 / PubMed / Full text
SUV39H1
- Increase in hippocampal histone H3K9me3 is negatively correlated with memory in old male mice. / 04.2020 / PubMed / Full text
- Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation / 27.09.2017 / PubMed / Full text
E2F2
- MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment. / 08.2018 / PubMed / Full text
- In situ regeneration of retinal pigment epithelium by gene transfer of E2F2: a potential strategy for treatment of macular degenerations. / 12.2017 / PubMed / Full text
VCAN
- Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis. / 07.06.2019 / PubMed / Full text
- Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells. / 2019 / PubMed / Full text
EDARADD
- Age prediction in living: Forensic epigenetic age estimation based on blood samples. / 11.2020 / PubMed / Full text
- DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird. / 2017 / PubMed / Full text
TAT
- Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides. / 2019 / PubMed / Full text
- Effects of HIV-1 gp120 and TAT-derived microvesicles on endothelial cell function. / 01.05.2019 / PubMed / Full text
TCF7L2
- A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder. / 03.2020 / PubMed / Full text
- Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle. / 01.03.2019 / PubMed / Full text
GRIK2
- Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2. / 11-12.2020 / PubMed / Full text
- Isoforms of Ionotropic Glutamate Receptor GRIK2 Induce Senescence of Carcinoma Cells. / 01-02.2019 / PubMed / Full text
TTN
- LncRNA TTN-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis. / 10.10.2019 / PubMed / Full text
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
PIEZO1
- Niche stiffness underlies the ageing of central nervous system progenitor cells. / 09.2019 / PubMed / Full text
- On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, PIEZO1, and Gardos Channels. / 2017 / PubMed / Full text
HAPLN1
- Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility. / 01.2019 / PubMed / Full text
- Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis. / 01.2019 / PubMed / Full text
DAPK1
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
- Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging. / 05.2019 / PubMed / Full text
KIT
- Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-KIT. / 04.2020 / PubMed / Full text
- miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. / 06.2018 / PubMed / Full text
RIG
- Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling. / 2017 / PubMed / Full text
- Aging impairs both primary and secondary RIG-I signaling for interferon induction in human monocytes. / 12.12.2017 / PubMed / Full text
CXCL5
- Hassall's corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus. / 05.03.2019 / PubMed / Full text
- Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age. / 09.2018 / PubMed / Full text
MEIS1
- Down-regulation of MEIS1 promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes. / 06.2019 / PubMed / Full text
- Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text
CCNG2
- A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. / 2018 / PubMed / Full text
- Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text
BGN
- Alterations of local functional connectivity in lifespan: A resting-state fMRI study. / 07.2020 / PubMed / Full text
- Exploring variability in basal ganglia connectivity with functional MRI in healthy aging. / 12.2018 / PubMed / Full text
TRPM8
- Morphological and functional changes in TRPM8-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice. / 01.08.2018 / PubMed / Full text
- A comparative study on the therapeutic effect of TRPV1, TRPA1, and TRPM8 agonists on swallowing dysfunction associated with aging and neurological diseases. / 02.2018 / PubMed / Full text
HLA-A
- Reduced expression of the lncRNA NRON is a potential hallmark of the CMV-amplified CD8+ T cell accumulations commonly seen in older humans. / 01.2019 / PubMed / Full text
- Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. / 2017 / PubMed / Full text
PER1
- Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells. / 02.2020 / PubMed / Full text
- Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text
RUNX1
- RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins. / 03.2018 / PubMed / Full text
- Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text
CCL21
- CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults. / 26.03.2019 / PubMed / Full text
- Changes in expression of klotho affect physiological processes, diseases, and cancer. / 01.2018 / PubMed / Full text
PIK3CG
- Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway. / 10.06.2019 / PubMed / Full text
- MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells. / 18.03.2019 / PubMed / Full text
TBK1
- Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of TBK1 to facilitate mitophagy. / 01.01.2021 / PubMed / Full text
- TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. / 06.09.2018 / PubMed / Full text
AMT
- A multi-method comparison of autobiographical memory impairments amongst younger and older adults. / 12.03.2020 / PubMed / Full text
- Autobiographical Memory From Different Life Stages in Individuals With Obstructive Sleep Apnea. / 03.2019 / PubMed / Full text
CDK1
- MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging. / 02.2020 / PubMed / Full text
- Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells. / 2018 / PubMed / Full text
FN1
- Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. / 22.07.2019 / PubMed / Full text
- Effects of Fibronectin 1 on Cell Proliferation, Senescence and Apoptosis of Human Glioma Cells Through the PI3K/AKT Signaling Pathway. / 2018 / PubMed / Full text
HCN1
- Protein expression changes of HCN1 and HCN2 in hippocampal subregions of gerbils during the normal aging process. / 11.2019 / PubMed / Full text
- HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation. / 15.02.2019 / PubMed / Full text
TRPC6
- Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype. / 11.2020 / PubMed / Full text
- TRPC6 in simulated microgravity of intervertebral disc cells. / 10.2018 / PubMed / Full text
ALKBH8
- Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming . / 01.2020 / PubMed / Full text
- ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed
PF4
- TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity. / 07.2019 / PubMed / Full text
- Effects of collagen peptides intake on skin ageing and platelet release in chronologically aged mice revealed by cytokine array analysis. / 01.2018 / PubMed / Full text
MAPK3
- A tyrosine kinase-activating variant Asn666Ser in PDGFRB causes a progeria-like condition in the severe end of Penttinen syndrome. / 04.2019 / PubMed / Full text
- Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. / 10.2018 / PubMed / Full text
GATA3
- An imbalance in the T-helper phenotypes displayed by senescent CD4 CD28 T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus. / 11.2018 / PubMed / Full text
- Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland. / 12.2018 / PubMed / Full text
HLA-DPB1
- 17th IHIW component "Immunogenetics of Ageing" - New NGS data. / 09.2019 / PubMed / Full text
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
BAK1
- Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon. / 23.09.2020 / PubMed / Full text
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
BECN1
- Calpain-dependent Beclin1 cleavage stimulates senescence-associated cell death in HT22 hippocampal cells under the oxidative stress conditions. / 14.05.2019 / PubMed / Full text
- Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-ULK1 signaling pathway. / 04.2018 / PubMed / Full text
TIMP1
- Design, cyclization, and optimization of MMP13-TIMP1 interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis. / 01.2019 / PubMed / Full text
- Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9. / 2018 / PubMed / Full text
APOA5
- Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency. / 03.2019 / PubMed / Full text
- Longitudinal interaction between APOA5 -1131T>C and overweight in the acceleration of age-related increase in arterial stiffness through the regulation of circulating triglycerides. / 02.2019 / PubMed / Full text
FOXF1
- Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence. / 17.08.2018 / PubMed / Full text
- Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text
GK
- Progression of diabetic kidney disease in T2DN rats. / 01.12.2019 / PubMed / Full text
- Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging. / 04.2019 / PubMed / Full text
TMPRSS2
- Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants. / 09.09.2020 / PubMed / Full text
- Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. / 03.06.2020 / PubMed / Full text
SOST
- Low Serum Levels of DKK2 Predict Incident Low-Impact Fracture in Older Women. / 07.2019 / PubMed / Full text
- Bone adaptation in response to treadmill exercise in young and adult mice. / 06.2018 / PubMed / Full text
S1PR1
- Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair. / 22.06.2020 / PubMed / Full text
- Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota. / 04.01.2018 / PubMed / Full text
PRC1
- Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein BMI1 in breast cancer cells. / 07.2018 / PubMed / Full text
- Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster. / 02.2018 / PubMed / Full text
MTMR14
- EDTP/MTMR14: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates. / 13.07.2019 / PubMed / Full text
- Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster. / 16.02.2019 / PubMed / Full text
ZSCAN10
- RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells. / 10.10.2017 / PubMed / Full text
- ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors. / 09.2017 / PubMed / Full text
CXCL11
- Endothelial cells under therapy-induced senescence secrete CXCL11, which increases aggressiveness of breast cancer cells. / 10.10.2020 / PubMed / Full text
- Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity. / 13.03.2019 / PubMed / Full text
ADAM17
- ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19. / 2020 / PubMed / Full text
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
HMOX1
- Well-aging: A new strategy for skin homeostasis under multi-stressed conditions. / 02.2020 / PubMed / Full text
- Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. / 08.2019 / PubMed / Full text
DLX5
- Inhibition of microRNA-27b-3p relieves osteoarthritis pain via regulation of KDM4B-dependent DLX5. / 09.2020 / PubMed / Full text
- Detection and evaluation of DNA methylation markers found at SCGN and KLF14 loci to estimate human age. / 11.2017 / PubMed / Full text
MARCO
- Age-dependent effect between MARCO and TLR4 on PMMA particle phagocytosis by macrophages. / 08.2019 / PubMed / Full text
- Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria. / 01.11.2017 / PubMed / Full text
CDKN2B
- Molecular Genetics and Functional Analysis Implicate [i]CDKN2BAS1-CDKN2B[/i] Involvement in POAG Pathogenesis. / 21.08.2020 / PubMed / Full text
- Interference of the long noncoding RNA CDKN2B-AS1 upregulates miR-181a-5p/TGFβI axis to restrain the metastasis and promote apoptosis and senescence of cervical cancer cells. / 04.2019 / PubMed / Full text
LIF
- Aminopeptidase N expression in the endometrium could affect endometrial receptivity. / 25.06.2019 / PubMed / Full text
- Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. / 15.03.2019 / PubMed / Full text
CCN3
- CCN3 Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta. / 2020 / PubMed / Full text
- CCN3 (NOV) Drives Degradative Changes in Aging Articular Cartilage. / 13.10.2020 / PubMed / Full text
FOXP3
- Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text
- Enhanced expression of PD-1 and other activation markers by CD4+ T cells of young but not old patients with metastatic melanoma. / 06.2018 / PubMed / Full text
PSEN2
- Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2. / 2020 / PubMed / Full text
- Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition. / 03.2020 / PubMed / Full text
C9orf72
- Carriership of two copies of C9orf72 hexanucleotide repeat intermediate-length alleles is a risk factor for ALS in the Finnish population. / 09.11.2020 / PubMed / Full text
- C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons. / 29.08.2018 / PubMed / Full text
DSP
- Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions. / 10.2019 / PubMed / Full text
- Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. / 05.2018 / PubMed / Full text
F7
- The Pattern of Mu Rhythm Modulation During Emotional Destination Memory: Comparison Between Mild Cognitive Impairment Patients and Healthy Controls. / 2019 / PubMed / Full text
- High levels of incidental physical activity are positively associated with cognition and EEG activity in aging. / 2018 / PubMed / Full text
ATG12
- Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
FANCD2
- TFG-maintaining stability of overlooked FANCD2 confers early DNA-damage response. / 24.10.2020 / PubMed / Full text
- FANCD2 and DNA Damage. / 19.08.2017 / PubMed / Full text
CAST
- Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance. / 05.11.2018 / PubMed / Full text
- Short Telomeres Induce p53 and Autophagy and Modulate Age-Associated Changes in Cardiac Progenitor Cell Fate. / 06.2018 / PubMed / Full text
DRD3
- Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality. / 02.2019 / PubMed / Full text
- Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study. / 07.2018 / PubMed / Full text
ID3
- Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
CHM
- [Molecular regulative mechanisms of aging and interventional effects of Chinese herbal medicine]. / 08.2017 / PubMed / Full text
- [Molecular mechanisms of autophagy in regulating renal aging and interventional effects of Chinese herbal medicine]. / 11.2016 / PubMed / Full text
GPR39
- Zinc-mediated Neurotransmission in Alzheimer's Disease: A Potential Role of the GPR39 in Dementia. / 2020 / PubMed / Full text
- GPR39 agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence. / 12.2019 / PubMed / Full text
B2M
- The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. / 03.2019 / PubMed / Full text
- Association between serum β2-microglobulin levels and frailty in an elderly Chinese population: results from RuLAS. / 2017 / PubMed / Full text
HBP1
- Suppression of p38/HBP1 pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence. / 03-04.2020 / PubMed / Full text
- Transcription factor HBP1: A regulator of senescence and apoptosis of preadipocytes. / 17.09.2019 / PubMed / Full text
DEGS1
- [Frailty: Prevalence in the Resident Population of Germany 70 - 79 Years of Age - a Population-Based Approach]. / 11.2017 / PubMed / Full text
- Physical exercise and cognitive function across the life span: Results of a nationwide population-based study. / 05.2018 / PubMed / Full text
ACOX1
- Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes. / 04.2019 / PubMed / Full text
- Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging. / 2018 / PubMed / Full text
TXNRD2
- Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression. / 10.2020 / PubMed / Full text
- Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice. / 22.03.2018 / PubMed / Full text
SAA1
- Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells. / 2018 / PubMed / Full text
- Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients. / 2017 / PubMed / Full text
STIM1
- Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis. / 02.2020 / PubMed / Full text
- Ca entry via TRPC1 is essential for cellular differentiation and modulates secretion via the SNARE complex. / 01.07.2019 / PubMed / Full text
LAMP2
- A pH probe inhibits senescence in mesenchymal stem cells. / 07.12.2018 / PubMed / Full text
- Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. / 02.2018 / PubMed / Full text
CPE
- Cross-Sectional and Cumulative Longitudinal Central Nervous System Penetration Effectiveness Scores Are Not Associated With Neurocognitive Impairment in a Well Treated Aging Human Immunodeficiency Virus-Positive Population in Switzerland. / 07.2019 / PubMed / Full text
- COCOA (Theobroma cacao) Polyphenol-Rich Extract Increases the Chronological Lifespan of Saccharomyces cerevisiae. / 2016 / PubMed
STAT5A
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
- SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes. / 28.10.2017 / PubMed / Full text
NTS
- Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension. / 08.2019 / PubMed / Full text
- Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. / 01.08.2018 / PubMed / Full text
PGP
- Age-associated changes of the intrinsic nervous system in relation with interstitial cells in the pre-weaning goat rumen. / 14.07.2019 / PubMed / Full text
- Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats. / 2017 / PubMed / Full text
GDF3
- In vivo GDF3 administration abrogates aging related muscle regeneration delay following acute sterile injury. / 10.2018 / PubMed / Full text
- Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. / 05.10.2017 / PubMed / Full text
TNNT3
- Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. / 06.02.2019 / PubMed / Full text
- Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs. / 15.07.2018 / PubMed / Full text
GPT
- Brain Structural-Behavioral Correlates Underlying Grooved Pegboard Test Performance Across Lifespan. / 07.07.2020 / PubMed / Full text
- Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults. / 2019 / PubMed / Full text
ANGPTL2
- Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study. / 01.05.2020 / PubMed / Full text
- Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice. / 02.02.2018 / PubMed / Full text
IL1A
- IL1B triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via CCL2. / 25.10.2020 / PubMed / Full text
- Age-associated mRNA expression changes in bovine endometrial cells in vitro. / 14.08.2017 / PubMed / Full text
PUM2
- PUMILIO hyperactivity drives premature aging of [i]Norad[/i]-deficient mice. / 08.02.2019 / PubMed / Full text
- The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging. / 21.02.2019 / PubMed / Full text
BTK
- Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition. / 01.2020 / PubMed / Full text
- BTK suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling. / 22.08.2017 / PubMed / Full text
MALT1
- MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. / 29.04.2020 / PubMed / Full text
- MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging. / 2019 / PubMed / Full text
DAO
- Age- and gender-dependent D-amino acid oxidase activity in mouse brain and peripheral tissues: implication for aging and neurodegeneration. / 01.08.2019 / PubMed / Full text
- Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging. / 01.11.2017 / PubMed / Full text
FSTL3
- Activin type II receptor signaling in cardiac aging and heart failure. / 06.03.2019 / PubMed / Full text
- Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise. / 01.10.2018 / PubMed / Full text
BMP15
- Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. / 01.2019 / PubMed / Full text
- Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. / 18.10.2017 / PubMed / Full text
GIT2
- Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories. / 12.2019 / PubMed / Full text
- GIT2-A keystone in ageing and age-related disease. / 05.2018 / PubMed / Full text
PTS
- Posttraumatic stress symptom persistence across 24 years: association with brain structures. / 08.2020 / PubMed / Full text
- Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis. / 18.07.2018 / PubMed / Full text
FUNDC1
- Mitochondria organize the cellular proteostatic response and promote cellular senescence. / 15.03.2019 / PubMed / Full text
- A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. / 01.02.2019 / PubMed / Full text
GNG3
- Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text
- Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text
CRABP2
- Preconception resveratrol intake against infertility: Friend or foe? / 04.2020 / PubMed / Full text
- Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females. / 31.10.2017 / PubMed / Full text
GRSF1
- GRSF1 is an age-related regulator of senescence. / 03.04.2019 / PubMed / Full text
- GRSF1 suppresses cell senescence. / 07.08.2018 / PubMed / Full text
BIN1
- Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice. / 20.03.2019 / PubMed / Full text
- Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text
IL7
- SCAMP4 enhances the senescent cell secretome. / 01.07.2018 / PubMed / Full text
- Thymic Atrophy: Experimental Studies and Therapeutic Interventions. / 01.2018 / PubMed / Full text
LOXL2
- Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice. / 27.09.2019 / PubMed / Full text
- Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening. / 01.07.2019 / PubMed / Full text
WIPI2
- Neuronal autophagy declines substantially with age and is rescued by overexpression of WIPI2. / 02.2020 / PubMed / Full text
- The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. / 04.2019 / PubMed / Full text
TBC1D5
- TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry. / 09.06.2020 / PubMed / Full text
- Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling. / 02.09.2019 / PubMed / Full text
PLK4
- A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence. / 05.2020 / PubMed / Full text
- Differential expression of AURKA/PLK4 in quiescence and senescence of osteosarcoma U2OS cells. / 04.2020 / PubMed / Full text
LCT
- Functional MRI of Letter Cancellation Task Performance in Older Adults. / 2019 / PubMed / Full text
- Milk Intake at Midlife and Cognitive Decline over 20 Years. The Atherosclerosis Risk in Communities (ARIC) Study. / 17.10.2017 / PubMed / Full text
XRCC1
- [Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats]. / 07.2018 / PubMed / Full text
- The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity. / 2018 / PubMed / Full text
GAS6
- Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text
- Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. / 2017 / PubMed / Full text
SPR
- Regulation of lifespan by neural excitation and REST. / 10.2019 / PubMed / Full text
- How many geriatricians should, at minimum, be staffing health regions in Australia? / 03.2018 / PubMed / Full text
RTEL1
- Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants. / 12.2019 / PubMed / Full text
- Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal. / 01.2018 / PubMed / Full text
CBL
- Effects of cerebrolysin on nerve growth factor system in the aging rat brain. / 2017 / PubMed / Full text
- Skeletal Muscle CAP Expression Increases after Dietary Restriction and Aerobic Training in Women with a History of Gestational Diabetes. / 2016 / PubMed / Full text
CCR6
- Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells. / 07.2019 / PubMed / Full text
- Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text
LONP1
- Mitochondria organize the cellular proteostatic response and promote cellular senescence. / 15.03.2019 / PubMed / Full text
- A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. / 01.02.2019 / PubMed / Full text
TRPM7
- mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development. / 10.2018 / PubMed / Full text
- Role of kinase-coupled TRP channels in mineral homeostasis. / 04.2018 / PubMed / Full text
PDCD4
- Petal abscission in roses is associated with the activation of a truncated version of the animal PDCD4 homologue, RbPCD1. / 11.2019 / PubMed / Full text
- PDCD4 Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression. / 2018 / PubMed / Full text
TLR7
- Bovine Lactoferrin Enhances TLR7-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D. / 2018 / PubMed / Full text
- B cell responses to apoptotic cells in MFG-E8-/- mice. / 2018 / PubMed / Full text
PGD
- Primary Care for the Elderly Bereaved: Recommendations for Medical Education. / 12.2018 / PubMed / Full text
- High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles. / 01.03.2018 / PubMed / Full text
PTX3
- Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. / 27.01.2020 / PubMed / Full text
- Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study. / 13.07.2020 / PubMed / Full text
TAS2R38
- TAS2R38 bitter taste receptor and attainment of exceptional longevity. / 02.12.2019 / PubMed / Full text
- Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. / 18.10.2018 / PubMed / Full text
ETS1
- The transcription factor ETS1 promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1. / 06.12.2019 / PubMed / Full text
- G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
SMAD4
- A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient. / 09.2019 / PubMed / Full text
- E47 Governs the MYC-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type p53. / 2018 / PubMed / Full text
DDB1
- DCAF1 regulates Treg senescence via the ROS axis during immunological aging. / 02.11.2020 / PubMed / Full text
- Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. / 15.06.2018 / PubMed / Full text
DKC1
- Successful liver transplantation in short telomere syndromes without bone marrow failure due to DKC1 mutation. / 05.2020 / PubMed / Full text
- Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. / 04.2018 / PubMed / Full text
DST
- Ancestral germen/soma distinction in microbes: Expanding the disposable soma theory of aging to all unicellular lineages. / 07.2020 / PubMed / Full text
- Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study. / 10.2019 / PubMed / Full text
S100A4
- Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice. / 15.12.2019 / PubMed / Full text
- Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. / 2018 / PubMed / Full text
DDX41
- Salidroside influences the cellular cross-talk of human fetal lung diploid fibroblasts: A proteomic approach. / 03.2018 / PubMed / Full text
- Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text
MVD
- Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density. / 12.2018 / PubMed / Full text
- Assessing Microvascular Function in Humans from a Chronic Disease Perspective. / 12.2017 / PubMed / Full text
GALT
- Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life. / 03.2019 / PubMed / Full text
- Dietary Animal Plasma Proteins Improve the Intestinal Immune Response in Senescent Mice. / 11.12.2017 / PubMed / Full text
GATA2
- GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice. / 04.2019 / PubMed / Full text
- Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text
ACTA1
- Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. / 15.05.2019 / PubMed / Full text
- Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. / 15.12.2017 / PubMed / Full text
CYP3A4
- Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. / 05.2019 / PubMed / Full text
- Effect of Age and Allele Variants of CYP3A5, CYP3A4, and POR Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. / 12.2017 / PubMed / Full text
ACTB
- Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text
- WNT-activated bone grafts repair osteonecrotic lesions in aged animals. / 27.10.2017 / PubMed / Full text
AGT
- SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence. / 06.2020 / PubMed / Full text
- Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
ZEB2
- miR-200b regulates cellular senescence and inflammatory responses by targeting ZEB2 in pulmonary emphysema. / 12.2020 / PubMed / Full text
- MicroRNA-145 induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by ZEB2. / 05.2019 / PubMed / Full text
PDE4D
- Phosphodiesterase PDE4D Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau. / 2020 / PubMed / Full text
- Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function. / 02.12.2018 / PubMed / Full text
RAD52
- Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae. / 01.08.2019 / PubMed / Full text
- Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human RAD52 gene in a cardiovascular cohort. / 10.2017 / PubMed / Full text
PPM1D
- Detectible mosaic truncating PPM1D mutations, age and breast cancer risk. / 06.2019 / PubMed / Full text
- Age-related remodelling of oesophageal epithelia by mutated cancer drivers. / 01.2019 / PubMed / Full text
CYP7A1
- Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats. / 2019 / PubMed / Full text
- Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). / 03.2018 / PubMed / Full text
APPL2
- The reversal effect of physical exercise on aging-related increases in APPL2 content in skeletal muscle. / 01.10.2018 / PubMed / Full text
- Adaptor Protein APPL2 Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor. / 07.2018 / PubMed / Full text
ABCA1
- Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension. / 01.07.2019 / PubMed / Full text
- Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. / 08.2018 / PubMed / Full text
MDH1
- Oxidative Damage to the TCA Cycle Enzyme MDH1 Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. / 03.04.2020 / PubMed / Full text
- Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro. / 08.2019 / PubMed / Full text
CD22
- CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. / 04.2019 / PubMed / Full text
- Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves. / 03.2018 / PubMed / Full text
HSPA1A
- Vitamin D3 treatment regulates apoptosis, antioxidant defense system, and DNA integrity in the epididymal sperm of an aged rat model. / 12.2019 / PubMed / Full text
- The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells. / 01.09.2018 / PubMed / Full text
HCRT
- Age-related central regulation of orexin and NPY in the short-lived African killifish Nothobranchius furzeri. / 15.05.2019 / PubMed / Full text
RRM2B
- Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs. / 15.07.2018 / PubMed / Full text
INPP4B
- [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text
PDGFRB
- A tyrosine kinase-activating variant Asn666Ser in PDGFRB causes a progeria-like condition in the severe end of Penttinen syndrome. / 04.2019 / PubMed / Full text
CYP2R1
- Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance. / 01.08.2018 / PubMed / Full text
CIP2A
- Inhibition of CIP2A attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma. / 08.01.2018 / PubMed / Full text
ANGPTL4
- Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. / 05.2019 / PubMed / Full text
FMO3
- Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver. / 11.2017 / PubMed / Full text
WLS
- Evaluation of three statistical prediction models for forensic age prediction based on DNA methylation. / 05.2018 / PubMed / Full text
BBS5
- Progressive Characterization of Visual Phenotype in Bardet-Biedl Syndrome Mutant Mice. / 01.03.2019 / PubMed / Full text
UCHL1
- Abolishing UCHL1's hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice. / 04.11.2020 / PubMed / Full text
PLA2G6
- Mutations in the Drosophila homolog of human PLA2G6 give rise to age-dependent loss of psychomotor activity and neurodegeneration. / 13.02.2018 / PubMed / Full text
FMR1
- Static and dynamic postural control deficits in aging fragile X mental retardation 1 (FMR1) gene premutation carriers. / 21.01.2019 / PubMed / Full text
MAP1A
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
IL13
- Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text
DUSP8
- MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats. / 12.2019 / PubMed / Full text
TNFSF15
- Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens. / 11.2018 / PubMed / Full text
FAR2
NOA1
- The dependence of leaf senescence on the balance between 1-aminocyclopropane-1-carboxylate acid synthase 1 (ACS1)-catalysed ACC generation and nitric oxide-associated 1 (NOS1)-dependent NO accumulation in Arabidopsis. / 07.2019 / PubMed / Full text
SPP1
- Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age. / 04.2018 / PubMed / Full text
TOR2A
- The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. / 05.06.2018 / PubMed / Full text
WFIKKN2
- Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults. / 01.01.2019 / PubMed / Full text
ACMSD
- De novo NAD synthesis enhances mitochondrial function and improves health. / 11.2018 / PubMed / Full text
HSD3B2
PREP
- Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text
OSM
- Age Differences in Sexual Minority Stress and the Importance of Friendship in Later Life. / 04.11.2020 / PubMed / Full text
UGT2B7
- Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. / 05.2019 / PubMed / Full text
EDN1
- Dexamethasone downregulates SIRT1 and IL6 and upregulates EDN1 genes in stem cells derived from gingivae via the AGE/RAGE pathway. / 03.2018 / PubMed / Full text
NAIP
PIK3C2A
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
NUCB2
- Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise Killifish. / 31.12.2019 / PubMed / Full text
ACTR3B
- Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text
HES1
DRD1
- Impact of dopamine-related genetic variants on physical activity in old age - a cohort study. / 24.05.2020 / PubMed / Full text
PSMB8
- [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text
GP6
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
AOX1
MRO
- [Effects of different intensities exercise combined with resveratrol on RBP4 in aged obese rats]. / 08.05.2017 / PubMed / Full text
LRP1
- Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome. / 06.2020 / PubMed / Full text
RXRG
- Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. / 2017 / PubMed / Full text
GORAB
- Examining tissue composition, whole-bone morphology and mechanical behavior of Gorab mice tibiae: A mouse model of premature aging. / 08.12.2017 / PubMed / Full text
PABPN1
- Dysfunctional transcripts are formed by alternative polyadenylation in OPMD. / 26.09.2017 / PubMed / Full text
CBX8
- PIM1-catalyzed CBX8 phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast. / 27.06.2018 / PubMed / Full text
BAG3
- Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner. / 03.2018 / PubMed / Full text
KCNAB3
SRSF3
- Alternative polyadenylation dependent function of splicing factor SRSF3 contributes to cellular senescence. / 04.03.2019 / PubMed / Full text
NGFR
- Evidence for changing nerve growth factor signalling mechanisms during development, maturation and ageing in the rat molar pulp. / 02.2019 / PubMed / Full text
COQ7
- Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text
GPX2
- RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells. / 10.10.2017 / PubMed / Full text
PRKCH
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
FASN
- Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
SAT1
- Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action. / 08.2020 / PubMed / Full text
GADD45B
- Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging? / 2019 / PubMed / Full text
SALL1
- SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex. / 06.04.2018 / PubMed / Full text
LRP2
- Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis. / 27.11.2018 / PubMed / Full text
PDK4
- Putrescine delays postovulatory aging of mouse oocytes by upregulating PDK4 expression and improving mitochondrial activity. / 16.12.2018 / PubMed / Full text
TRIM28
- Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau. / 04.06.2018 / PubMed / Full text
RRAD
- Pan-senescence transcriptome analysis identified RRAD as a marker and negative regulator of cellular senescence. / 01.2019 / PubMed / Full text
ECRG4
COL6A1
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
FSTL1
CREB5
- Cellular senescence induces replication stress with almost no affect on DNA replication timing. / 2018 / PubMed / Full text
MTRR
- One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults. / 12.2019 / PubMed / Full text
FADD
- Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal FADD. / 11.2018 / PubMed / Full text
SND1
- [Downregulation of SND1 Expression Accelerates Cell Senescence of Human Diploid Fibroblasts 2BS via Modulating the SASP]. / 05.2020 / PubMed / Full text
DDR1
- Age-related modifications of type I collagen impair DDR1-induced apoptosis in non-invasive breast carcinoma cells. / 2018 / PubMed / Full text
ST18
- [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text
TGM2
- Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
SP1
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
CIZ1
RORA
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
FOXP2
- Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization. / 06.11.2018 / PubMed / Full text
STC2
- Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2. / 05.12.2019 / PubMed / Full text
CXCR5
- Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses. / 17.08.2017 / PubMed / Full text
DDR2
- Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging. / 03.2018 / PubMed / Full text
DBH
- ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children. / 04.2019 / PubMed / Full text
NMUR1
- [Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules]. / 2019 / PubMed / Full text
TXN
- Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice. / 15.11.2017 / PubMed / Full text
HJV
- Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting. / 06.2019 / PubMed / Full text
TP73
- G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
MICB
PTN
- Connecting Metainflammation and Neuroinflammation Through the PTN-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development. / 2019 / PubMed / Full text
MCM3
UCN
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
IGFBP7
- Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7. / 03.2020 / PubMed / Full text
KLF2
- KLF2 induces the senescence of pancreatic cancer cells by cooperating with FOXO4 to upregulate p21. / 01.03.2020 / PubMed / Full text
LIPA
- Influence of Habitual Physical Behavior - Sleeping, Sedentarism, Physical Activity - On Bone Health in Community-Dwelling Older People. / 2019 / PubMed / Full text
SMARCB1
- High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer. / 17.10.2017 / PubMed / Full text
IP6K1
- The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle. / 2019 / PubMed / Full text
NBR1
- Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner. / 03.2018 / PubMed / Full text
PPP2R3C
- The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver. / 04.2019 / PubMed / Full text
CFH
- The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. / 13.06.2018 / PubMed / Full text
USP8
- Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction. / 04.2019 / PubMed / Full text
PRNP
- Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS. / 06.2020 / PubMed / Full text
SV2B
- Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. / 10.2018 / PubMed / Full text
CCN4
BANF1
- An additional case of Néstor-Guillermo progeria syndrome diagnosed in early childhood. / 10.2020 / PubMed / Full text
TNP2
SMYD2
- Collaboration of MYC and RUNX2 in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity. / 10.2019 / PubMed / Full text
GDF9
- Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. / 18.10.2017 / PubMed / Full text
KLF5
- EGR1 promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling. / 01.09.2019 / PubMed / Full text
BTC
- Behavioral tagging and capture: long-term memory decline in middle-aged rats. / 07.2018 / PubMed / Full text
BARD1
- BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in [i]Caenorhabditis elegans[/i]. / 12.2018 / PubMed / Full text
PEBP1
- [i]Drosophila[/i] PEBP1 inhibits intestinal stem cell aging via suppression of ERK pathway. / 06.04.2018 / PubMed / Full text
NMI
- Age-Dependent Control of Shoulder Muscles During a Reach-and-Lift Task. / 10.12.2019 / PubMed / Full text
TAF7
- Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. / 22.01.2020 / PubMed / Full text
NLRX1
- NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells. / 26.02.2018 / PubMed / Full text
HHLA2
- Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma. / 05.2019 / PubMed / Full text
WT1
- Age and weight at first mating affects plasma leptin concentration but no effects on reproductive performance of gilts. / 09.2019 / PubMed / Full text
PPARG
- The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity. / 04-06.2018 / PubMed / Full text
PTK7
- Innate and adaptive immune dysregulation in critically ill ICU patients. / 05.07.2018 / PubMed / Full text
VASH1
- Double-Face of Vasohibin-1 for the Maintenance of Vascular Homeostasis and Healthy Longevity. / 01.06.2018 / PubMed / Full text
TRAV27
- Perturbed CD8 T cell immunity across universal influenza epitopes in the elderly. / 02.2018 / PubMed / Full text
ACSL5
- Ageing sensitized by iPLA β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids. / 12.2017 / PubMed / Full text
HNRNPA0
- The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. / 10.2019 / PubMed / Full text
MCF2L
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
ALOX12
- Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer. / 15.05.2020 / PubMed / Full text
RARB
- Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. / 12.2019 / PubMed / Full text
COL1A1
- Remodeling process in bone of aged rats in response to resistance training. / 01.09.2020 / PubMed / Full text
ATF2
- Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium. / 01.04.2018 / PubMed / Full text
USF2
- Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice. / 15.10.2018 / PubMed / Full text
CLN3
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
GNAQ
- GNAQ expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system. / 01.2020 / PubMed / Full text
MC1R
- In vitro behavior and UV response of melanocytes derived from carriers of [[CDKN2A]] mutations and MC1R variants. / 03.2019 / PubMed / Full text
ERCC5
- Identification of a ERCC5 c.2333T>C (L778P) Variant in Two Tunisian Siblings With Mild Xeroderma Pigmentosum Phenotype. / 2019 / PubMed / Full text
S1PR3
- Sexual dimorphism of metabolic and vascular dysfunction in aged mice and those lacking the sphingosine 1-phosphate receptor 3. / 01.12.2017 / PubMed / Full text
SATB2
- microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia. / 06.2019 / PubMed / Full text
SELENOK
- Dietary selenium deficiency and supplementation differentially modulate the expression of two ER-resident selenoproteins (selenoprotein K and selenoprotein M) in the ovaries of aged mice: Preliminary data. / 09.2020 / PubMed / Full text
GAB2
- Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936. / 01.12.2017 / PubMed / Full text
ITGA3
- A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells. / 17.08.2020 / PubMed / Full text
NRM
- Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation. / 12.2019 / PubMed / Full text
PRM2
DLAT
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
ACAT2
- Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. / 15.12.2017 / PubMed / Full text
UBTF
- Age-associated dysregulation of protein metabolism in the mammalian oocyte. / 12.2017 / PubMed / Full text
WFIKKN1
- Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults. / 01.01.2019 / PubMed / Full text
GSTM3
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
YES1
- Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies. / 20.10.2018 / PubMed / Full text
GSN
- Oral administration of alcalase potato protein hydrolysate-APPH attenuates high fat diet-induced cardiac complications via TGF-β/GSN axis in aging rats. / 01.2019 / PubMed / Full text
RB1
- G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
MR1
LRP8
- SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE. / 02.07.2019 / PubMed / Full text
HLA-DMA
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
OOEP
- Maternal gene [i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes. / 18.11.2018 / PubMed / Full text
ACAN
- MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway. / 15.04.2019 / PubMed / Full text
SOX13
- In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text
TOP1
- UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis. / 12.06.2018 / PubMed / Full text
ST6GAL1
HSP90AA1
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
ZNF467
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
CYP26A1
- Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text
SDC4
- Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. / 01.10.2017 / PubMed / Full text
RPA2
- Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text
HSPG2
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
NEK2
- Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma. / 21.11.2018 / PubMed / Full text
MAOA
- Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. / 05.10.2017 / PubMed / Full text
HSPB1
- The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity. / 06.2019 / PubMed / Full text
LTF
- Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text
EID3
- Upregulation of EID3 sensitizes breast cancer cells to ionizing radiation-induced cellular senescence. / 11.2018 / PubMed / Full text
GRM3
- Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk. / 04.2020 / PubMed / Full text
USP7
- Deubiquitinase USP7 regulates [i]Drosophila[/i] aging through ubiquitination and autophagy. / 20.11.2020 / PubMed / Full text
JAK3
- Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. / 04.2018 / PubMed / Full text
ULK2
- miR-26a suppresses autophagy in swine Sertoli cells by targeting ULK2. / 08.2018 / PubMed / Full text
SPHK1
- Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina. / 10.2019 / PubMed / Full text
CTC1
- CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length. / 08.2018 / PubMed / Full text
CXCL16
- CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4 T-Cell-Dependent Control of Senescence. / 05.2019 / PubMed / Full text
ENTPD7
- Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 (ENTPD7). / 23.08.2019 / PubMed / Full text
P2RY10
- Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury. / 12.06.2019 / PubMed / Full text
IFNG
- Glutathione Peroxidase 3 Delivered by hiPSC-MSCs Ameliorated Hepatic IR Injury via Inhibition of Hepatic Senescence. / 2018 / PubMed / Full text
PTTG1
- [Down-regulated PTTG1 expression promotes the senescence of human prostate cancer LNCaP-AI]. / 03.2019 / PubMed
CYP1B1
- Bisphenol A induces DSB-ATM-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts. / 04.2018 / PubMed / Full text
MCM6
LMX1A
- Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain. / 13.11.2018 / PubMed / Full text
POLL
- Temporal trends in loss of life expectancy after a cancer diagnosis among the Australian population. / 04.2020 / PubMed / Full text
TGFB1
- Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease. / 11.2017 / PubMed / Full text
IFIT1
- Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text
UBE2E3
- Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence. / 07.2018 / PubMed / Full text
PAX7
- Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits. / 10.2018 / PubMed / Full text
PTPRR
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
ABCC9
- TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels. / 05.2019 / PubMed / Full text
NFATC1
- Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. / 02.10.2017 / PubMed / Full text
EIF4E
- Transcriptomic evidence that insulin signalling pathway regulates the ageing of subterranean termite castes. / 18.05.2020 / PubMed / Full text
SCAMP4
MYSM1
- MYSM1 Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan. / 11.2020 / PubMed / Full text
INHBA
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
BTG1
OMD
- Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. / 06.02.2019 / PubMed / Full text
IMMP2L
- Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. / 06.2018 / PubMed / Full text
TRIB2
- TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling. / 12.12.2018 / PubMed / Full text
ABLIM3
- Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization. / 05.2018 / PubMed / Full text
USF1
- The rs2516839 variation of USF1 gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+ study. / 01.2019 / PubMed / Full text
ASMT
- The influence of ageing on the extrapineal melatonin synthetic pathway. / 09.2018 / PubMed / Full text
ERBB4
- Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways. / 03.2019 / PubMed / Full text
CHRNE
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
CPT1B
- Effects of carnitine palmitoyltransferases on cancer cellular senescence. / 02.2019 / PubMed / Full text
CNP
- Environmental Enrichment Elicits a Transient Rise of Bioactive C-Type Natriuretic Peptide in Young but Not Aged Rats. / 2018 / PubMed / Full text
MCAT
ALKBH2
- ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed
SELENOP
- Analyses of Selenotranscriptomes and Selenium Concentrations in Response to Dietary Selenium Deficiency and Age Reveal Common and Distinct Patterns by Tissue and Sex in Telomere-Dysfunctional Mice. / 10.2017 / PubMed / Full text
ELF3
- High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in [i]Arabidopsis[/i]. / 31.07.2020 / PubMed / Full text
SCN9A
- The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway. / 06.2018 / PubMed / Full text
ZBTB16
- miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. / 06.2018 / PubMed / Full text
NDUFV2
- Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text
NEFM
- Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age. / 06.2019 / PubMed / Full text
GPC1
- Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing. / 15.10.2019 / PubMed / Full text
NEIL1
- NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress. / 09.2019 / PubMed / Full text
SRY
- Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics. / 26.12.2017 / PubMed / Full text
SCGN
- Detection and evaluation of DNA methylation markers found at SCGN and KLF14 loci to estimate human age. / 11.2017 / PubMed / Full text
PYCR1
- A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals POSTN As a New Element in Proline Metabolic Disorder. / 12.2018 / PubMed / Full text
PGLS
- 547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates. / 28.11.2019 / PubMed / Full text
CASP3
- Does cartilage ERα overexpression correlate with osteoarthritic chondrosenescence? Indications from [i]Labisia pumila[/i] OA mitigation. / 09.2019 / PubMed
CLEC4E
- Comparative analysis of microbial sensing molecules in mucosal tissues with aging. / 03.2018 / PubMed / Full text
GRID1
- Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. / 03.2020 / PubMed / Full text
IPMK
- Inositol Polyphosphate Multikinase ([i]IPMK[/i]), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity. / 08.02.2019 / PubMed / Full text
EIF2B1
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
WNK1
- Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2. / 10.2018 / PubMed / Full text
BCL2L11
- miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence. / 01.2020 / PubMed / Full text
ARID5A
- Differentially regulated gene expression in quiescence versus senescence and identification of ARID5A as a quiescence associated marker. / 05.2018 / PubMed / Full text
SELENOW
- The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text
PON1
- Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview. / 02.05.2019 / PubMed / Full text
PRKDC
- DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis. / 29.08.2019 / PubMed / Full text
MAPK11
- lncRNA ENSMUST00000134285 Increases MAPK11 Activity, Regulating Aging-Related Myocardial Apoptosis. / 09.07.2018 / PubMed / Full text
CCNA2
- Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan. / 31.03.2018 / PubMed / Full text
EPHA2
DLGAP2
- Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. / 01.09.2020 / PubMed / Full text
PIGR
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
STK3
- Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. / 11.12.2018 / PubMed / Full text
CARF
- Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential. / 22.05.2020 / PubMed / Full text
MAP2K3
- Associations of [i]MAP2K3[/i] Gene Variants With Superior Memory in SuperAgers. / 2018 / PubMed / Full text
IRF1
- Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text
ALK
RSF1
- The SR proteins SF2 and RBP1 regulate triglyceride storage in the fat body of Drosophila. / 27.08.2019 / PubMed / Full text
CDC25A
- Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage. / 10.10.2020 / PubMed / Full text
P4HA3
- Age-associated genes in human mammary gland drive human breast cancer progression. / 15.06.2020 / PubMed / Full text
SLC15A2
- Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing. / 02.2019 / PubMed / Full text
CREB1
- Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons. / 29.08.2018 / PubMed / Full text
CUX1
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
APOC3
CBX4
- Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis. / 26.03.2019 / PubMed / Full text
PLK1
- Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text
RUNX3
- circLARP4 induces cellular senescence through regulating miR-761/RUNX3/p53/p21 signaling in hepatocellular carcinoma. / 02.2019 / PubMed / Full text
CCND3
- The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text
LDLR
- Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice. / 08.2018 / PubMed / Full text
SUN2
- Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging. / 26.02.2019 / PubMed / Full text
PPA2
- Characterization of long living yeast deletion mutants that lack mitochondrial metabolism genes DSS1, PPA2 and AFG3. / 20.07.2019 / PubMed / Full text
TXNDC5
MAP4K3
NKX2-5
- Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart. / 07.01.2019 / PubMed / Full text
TJP1
- Morphological and immunohistochemical characteristics of the equine corneal epithelium. / 11.2019 / PubMed / Full text
MAS1
- AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation. / 17.04.2018 / PubMed / Full text
IL4
- Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia. / 01.01.2018 / PubMed / Full text
TRIM27
- TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination. / 04.12.2020 / PubMed / Full text
FBXO46
- The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence. / 19.10.2018 / PubMed / Full text
MATN3
- Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis. / 19.01.2020 / PubMed / Full text
TRIB3
- Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text
BCL11B
- Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells. / 05.2018 / PubMed / Full text
TRPC1
- Ca entry via TRPC1 is essential for cellular differentiation and modulates secretion via the SNARE complex. / 01.07.2019 / PubMed / Full text
DEPTOR
SYNJ2
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
RNF144A
- Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. / 09.2019 / PubMed / Full text
PKD1
- The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response. / 16.03.2018 / PubMed / Full text
PDHB
- Neuron-specific knockdown of Drosophila PDHB induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting. / 15.05.2018 / PubMed / Full text
NLRP1
- NADPH oxidase 2-mediated NLRP1 inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro. / 04.2019 / PubMed / Full text
GYS2
- In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers. / 04.2018 / PubMed / Full text
MS4A1
- Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text
LPAR3
- Upregulated microRNA-15b alleviates ovarian cancer through inhitbition of the PI3K/Akt pathway by targeting LPAR3. / 12.2019 / PubMed / Full text
DYRK1A
- Altered age-linked regulation of plasma DYRK1A in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load. / 2020 / PubMed / Full text
HSD17B14
- Bisphenol A induces DSB-ATM-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts. / 04.2018 / PubMed / Full text
GNPAT
- Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells. / 05.2019 / PubMed / Full text
SMAD1
- TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands. / 26.11.2019 / PubMed / Full text
PDE10A
- Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain. / 01.2018 / PubMed / Full text
ATXN1
- Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text
KCTD12
- The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort. / 2020 / PubMed / Full text
PHB
- Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation. / 02.2019 / PubMed / Full text
CYP26B1
- Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia. / 20.05.2020 / PubMed / Full text
ATXN3
- Rescue of ATXN3 neuronal toxicity in [i]Caenorhabditis[/i][i]elegans[/i] by chemical modification of endoplasmic reticulum stress. / 19.12.2017 / PubMed / Full text
PCMTD1
- Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text
GCAT
- Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis. / 03.04.2018 / PubMed / Full text
KDM4A
- Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines. / 15.01.2019 / PubMed / Full text
TBC1D1
- Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text
FER
- Tracking the recognition of static and dynamic facial expressions of emotion across the life span. / 04.09.2018 / PubMed / Full text
MAP3K5
- Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. / 08.10.2018 / PubMed / Full text
KLB
- Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. / 2018 / PubMed / Full text
CHEK2
- A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text
RBM3
- Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. / 2018 / PubMed / Full text
TP53INP1
- TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling. / 02.01.2019 / PubMed / Full text
FOXD1
- MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1. / 12.2018 / PubMed / Full text
ALDH3A1
- Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs). / 13.02.2019 / PubMed / Full text
GRIN2B
- Medial temporal lobe atrophy relates more strongly to sleep-wake rhythm fragmentation than to age or any other known risk. / 04.2019 / PubMed / Full text
MCM4
ZNF207
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
MPST
- Methionine restriction leads to hyperhomocysteinemia and alters hepatic H S production capacity in Fischer-344 rats. / 12.2018 / PubMed / Full text
TPH1
- [i]Lactobacillus plantarum[/i] DR7 improved brain health in aging rats via the serotonin, inflammatory and apoptosis pathways. / 02.12.2020 / PubMed / Full text
NRXN3
- Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text
SDC3
- Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. / 01.10.2017 / PubMed / Full text
HLA-DQB1
- Identification of new genetic variants of HLA-DQB1 associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population. / 10.11.2017 / PubMed / Full text
APLP2
- Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex. / 06.2019 / PubMed / Full text
EZR
- Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model. / 03.2018 / PubMed / Full text
RAD51C
- Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population. / 06.2019 / PubMed / Full text
GPBAR1
- Activation of the bile acid receptor GPBAR1 (TGR5) ameliorates interleukin-1β (IL-1β)- induced chondrocytes senescence. / 10.2018 / PubMed / Full text
MS4A6A
- Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text
UCN3
- Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise-induced threshold shift. / 08.2019 / PubMed / Full text
CTSS
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
MECOM
- Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease. / 11.2018 / PubMed / Full text
CA12
- Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text
SDHB
- Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. / 12.02.2020 / PubMed / Full text
DUSP1
EVL
- Health Years in Total: A New Health Objective Function for Cost-Effectiveness Analysis. / 01.2020 / PubMed / Full text
PRKN
- PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. / 03.2019 / PubMed / Full text
BNC1
- Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. / 22.01.2020 / PubMed / Full text
SMN1
- Changing respiratory expectations with the new disease trajectory of nusinersen treated spinal muscular atrophy [SMA] type 1. / 09.2018 / PubMed / Full text
PDE9A
- Identification of new PDE9A isoforms and how their expression and subcellular compartmentalization in the brain change across the life span. / 05.2018 / PubMed / Full text
EXD2
- EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. / 02.2018 / PubMed / Full text
GOT1
- Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text
OGA
- NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase. / 19.11.2019 / PubMed / Full text
PRRX1
- A SIRT1-centered circuitry regulates breast cancer stemness and metastasis. / 12.2018 / PubMed / Full text
TINF2
- Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. / 04.2018 / PubMed / Full text
USP15
- Deficiency of parkin and PINK1 impairs age-dependent mitophagy in [i]Drosophila[/i]. / 29.05.2018 / PubMed / Full text
LGALS3
- Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. / 2018 / PubMed / Full text
ATP6V0C
ARID1B
FRG1
- Intergenerational response of steroidogenesis-related genes to maternal malnutrition. / 10.2019 / PubMed / Full text
PTPRD
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
ADRM1
- Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. / 01.08.2018 / PubMed / Full text
ESPL1
- Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants. / 09.2020 / PubMed / Full text
PGK2
- Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice. / 01.2020 / PubMed / Full text
IL18
PDE5A
- Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass. / 23.06.2020 / PubMed / Full text
SIX3
- CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type. / 30.11.2018 / PubMed / Full text
RAD51B
- Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human RAD52 gene in a cardiovascular cohort. / 10.2017 / PubMed / Full text
MLH3
- Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes. / 19.10.2017 / PubMed / Full text
KCNB1
- Oxidation of KCNB1 potassium channels in the murine brain during aging is associated with cognitive impairment. / 14.05.2019 / PubMed / Full text
AHCY
- Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
WDR73
- Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text
INHBE
- Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text
FOXN1
- Thymic rejuvenation via FOXN1-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation. / 17.09.2020 / PubMed / Full text
TRIP13
- BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome. / 02.01.2020 / PubMed / Full text
IL17RA
- Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon. / 2017 / PubMed / Full text
MRPS5
- Mutant MRPS5 affects mitoribosomal accuracy and confers stress-related behavioral alterations. / 11.2018 / PubMed / Full text
TEF
- Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response. / 10.2020 / PubMed / Full text
HPD
- Protein-Amino Acid Metabolism Disarrangements: The Hidden Enemy of Chronic Age-Related Conditions. / 22.03.2018 / PubMed / Full text
RXRA
- The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling. / 12.2018 / PubMed / Full text
RPS19BP1
- Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence. / 10.2020 / PubMed / Full text
UQCRC2
- Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10). / 06.2018 / PubMed / Full text
ITK
NSF
- Effects of air pollution on children from a socioecological perspective. / 15.11.2019 / PubMed / Full text
COL12A1
SELENOT
- The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text
FA2H
- C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production. / 2018 / PubMed / Full text
RACK1
- Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging. / 05.11.2019 / PubMed / Full text
FAHD1
- Oxaloacetate decarboxylase FAHD1 - a new regulator of mitochondrial function and senescence. / 01.2019 / PubMed / Full text
MST1
- [Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. / 25.06.2019 / PubMed
NTHL1
- Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals. / 04.2020 / PubMed / Full text
KCNQ4
- Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss. / 2020 / PubMed / Full text
ITGB4
- ITGB4 deficiency induces senescence of airway epithelial cells through p53 activation. / 03.2019 / PubMed / Full text
MRTFA
- Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse. / 01.02.2019 / PubMed / Full text
KLF6
- Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence. / 2019 / PubMed / Full text
FABP1
- Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken. / 01.09.2019 / PubMed / Full text
CHIA
- Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets. / 26.11.2018 / PubMed / Full text
SGSH
MX1
- Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection. / 10.11.2018 / PubMed / Full text
BCAS1
- Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs). / 13.02.2019 / PubMed / Full text
KCNQ2
- Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes. / 05.2018 / PubMed / Full text
CPT1A
- Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells. / 03.01.2020 / PubMed / Full text
ADNP2
- ADNP differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. / 06.2019 / PubMed / Full text
SMARCD1
- Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells. / 12.2018 / PubMed / Full text
ARNTL2
- Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text
SYP
- The neuropeptide-12 improves recognition memory and neuronal plasticity of the limbic system in old rats. / 08.2018 / PubMed / Full text
AXL
- Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells. / 01.2020 / PubMed / Full text
MSH3
- RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text
HAP1
- The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer. / 20.06.2018 / PubMed / Full text
EML6
NT5E
- The NT5E gene variant strongly affects the degradation rate of inosine 5'-monophosphate under postmortem conditions in Japanese Black beef. / 12.2019 / PubMed / Full text
- Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models. / 28.05.2019 / PubMed / Full text
PTK2B
- Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. / 11.2018 / PubMed / Full text
OXR1
GLI1
- Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text
SP7
- microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia. / 06.2019 / PubMed / Full text
SFRP5
- SFRP5 serves a beneficial role in arterial aging by inhibiting the proliferation, migration and inflammation of smooth muscle cells. / 11.2018 / PubMed / Full text
PPARGC1A
- Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. / 08.07.2019 / PubMed / Full text
HMGCS1
- The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain. / 15.10.2018 / PubMed / Full text
COQ6
- Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text
IGHD
TEP1
- [Influence of Age on the Susceptibility of Anopheles stephensi to Plasmodium berghei Infection]. / 12.2016 / PubMed
MAF
- Biocatalytic Degradation Efficiency of Postconsumer Polyethylene Terephthalate Packaging Determined by Their Polymer Microstructures. / 17.07.2019 / PubMed / Full text
NDUFS8
- Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity. / 01.10.2020 / PubMed / Full text
RPL36
- Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
CACNA1B
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
CBX3
- Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text
MEOX2
- Reduced expression of microRNA-130a promotes endothelial cell senescence and age-dependent impairment of neovascularization. / 26.05.2020 / PubMed / Full text
CLEC3B
- CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging. / 16.09.2020 / PubMed / Full text
ECSIT
- Longevity-related molecular pathways are subject to midlife "switch" in humans. / 08.2019 / PubMed / Full text
KRT15
- Extracellular proteoglycan decorin maintains human hair follicle stem cells. / 12.2018 / PubMed / Full text
SARM1
- Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy. / 03.10.2017 / PubMed / Full text
HLA-DPA1
GSTT1
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
IKBKB
- Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text
MAPK13
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
E2F3
- Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution. / 07.2018 / PubMed / Full text
PAX5
- Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low PAX5. / 08.2018 / PubMed / Full text
BHLHE40
- Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1. / 07.2020 / PubMed / Full text
TLR3
- Repetitive TLR3 activation in the lung induces skeletal muscle adaptations and cachexia. / 06.2018 / PubMed / Full text
PPFIA1
- Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text
RBP1
- The SR proteins SF2 and RBP1 regulate triglyceride storage in the fat body of Drosophila. / 27.08.2019 / PubMed / Full text
FGFR2
- Oncogenic mutations in histologically normal endometrium: the new normal? / 10.2019 / PubMed / Full text
SUCNR1
- [The effect of Mexidol on cerebral mitochondriogenesis at a young age and during aging]. / 2020 / PubMed / Full text
MMP12
- Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for MMP12 through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice. / 01.10.2017 / PubMed / Full text
STN1
- CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length. / 08.2018 / PubMed / Full text
NEO1
- Neogenin-1 distinguishes between myeloid-biased and balanced [i]Hoxb5[/i] mouse long-term hematopoietic stem cells. / 10.12.2019 / PubMed / Full text
CNTF
- Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha. / 01.10.2019 / PubMed / Full text
DYNC2H1
- Role for intraflagellar transport in building a functional transition zone. / 12.2018 / PubMed / Full text
PHGDH
- Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase. / 01.08.2019 / PubMed / Full text
HSPB6
- Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
DTNBP1
ATG16L1
- The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. / 04.2019 / PubMed / Full text
TAAR1
- Minimal Age-Related Alterations in Behavioral and Hematological Parameters in Trace Amine-Associated Receptor 1 (TAAR1) Knockout Mice. / 03.2020 / PubMed / Full text
MAFB
- Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy. / 01.04.2019 / PubMed / Full text
LRRK1
- Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice. / 15.11.2017 / PubMed / Full text
TECPR2
- Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging. / 01-03.2019 / PubMed / Full text
CCDC88A
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
NPAS2
- Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text
MAF1
- Beyond regulation of pol III: Role of MAF1 in growth, metabolism, aging and cancer. / 04.2018 / PubMed / Full text
MBD2
- Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords. / 02.2019 / PubMed / Full text
BRD2
- Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice. / 2020 / PubMed / Full text
SIK3
- Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids. / 25.09.2020 / PubMed / Full text
SLC52A3
- Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. / 01.11.2017 / PubMed / Full text
MAP1B
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
MGRN1
- Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis. / 06.2019 / PubMed / Full text
PTCH1
- Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text
GZMK
- Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK CD8 T Cells as Conserved Hallmark of Inflammaging. / 21.11.2020 / PubMed / Full text
HADHA
- Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells. / 2019 / PubMed / Full text
KDM2A
- SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. / 25.06.2020 / PubMed / Full text
LIN28B
- Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. / 2017 / PubMed / Full text
SUZ12
- Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. / 05.11.2018 / PubMed / Full text
HIF1A
- Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text
DGAT1
- Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPα-p300/DGAT1 pathway. / 02.2018 / PubMed / Full text
WNT5A
HLA-E
- Senescent cells evade immune clearance via HLA-E-mediated NK and CD8 T cell inhibition. / 03.06.2019 / PubMed / Full text
ELL
- Exceptional Longevity and Polygenic Risk for Cardiovascular Health. / 18.03.2019 / PubMed / Full text
SUN1
- Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging. / 26.02.2019 / PubMed / Full text
JUNB
- Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of JUNB. / 19.02.2020 / PubMed / Full text
NTN4
- EGF/EGFR upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence. / 04.12.2018 / PubMed / Full text
C2CD2
- Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort. / 20.11.2017 / PubMed / Full text
WNT7A
- Exogenous Expression of WNT7A in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents. / 2020 / PubMed / Full text
DLC1
- Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells. / 15.09.2018 / PubMed / Full text
CETP
- Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study. / 2018 / PubMed / Full text
GIT1
UPF1
- Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity. / 21.08.2017 / PubMed / Full text
SH2B3
- Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. / 13.10.2017 / PubMed / Full text
DEPDC5
- KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text
CASS4
ZNF396
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
MUC5AC
- InflammAging at Ocular Surface: Clinical and Biomolecular Analyses in Healthy Volunteers. / 01.04.2019 / PubMed / Full text
TNPO3
GCK
- The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing. / 12.2019 / PubMed / Full text
ZFHX3
NCK2
TGFBR2
- TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis. / 08.05.2019 / PubMed / Full text
ALDOA
- An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. / 06.2019 / PubMed / Full text
SLC24A5
HSPA5
- Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
SKAP2
- Longevity-related molecular pathways are subject to midlife "switch" in humans. / 08.2019 / PubMed / Full text
UACA
- Knockdown of [i]UACA[/i] inhibitsproliferation and invasion and promotes senescence of hepatocellular carcinoma cells. / 2018 / PubMed / Full text
UBE4B
- CircRNAs in the tree shrew ([i]Tupaia belangeri[/i]) brain during postnatal development and aging. / 30.04.2018 / PubMed / Full text
CUL3
- KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text
SFPQ
- Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis. / 08.04.2020 / PubMed / Full text
PEX5
- Aging lowers PEX5 levels in cortical neurons in male and female mouse brains. / 09.2020 / PubMed / Full text
RELA
- Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text
THBS4
- Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment. / 18.06.2019 / PubMed / Full text
TTL
- Longitudinal Associations of Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio with Biomarkers of Oxidative Stress in Older Adults: Results of a Large Cohort Study. / 2020 / PubMed / Full text
AKT2
- Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text
SCN2B
- MicroRNA‑449a regulates the progression of brain aging by targeting SCN2B in SAMP8 mice. / 04.2020 / PubMed / Full text
TRAF2
- The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium. / 12.2019 / PubMed / Full text
STK32C
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
RAF1
- Circular [i]ANRIL[/i] isoforms switch from repressors to activators of [i]p15/CDKN2B[/i] expression during RAF1 oncogene-induced senescence. / 29.09.2020 / PubMed / Full text
VPS29
- Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development. / 16.01.2019 / PubMed / Full text
TPRKB
- Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text
DPYSL2
- Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text
EIF2B2
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
ELOVL6
- An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. / 06.2019 / PubMed / Full text
G6PC3
- Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text
RPL30
- Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text
AKAP12
- A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter. / 05.2018 / PubMed / Full text
CD72
- Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation. / 2019 / PubMed / Full text
RPL31
- Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text
PEX19
- A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells. / 02.2020 / PubMed / Full text
TRAV1-2
CAP2
- Targeting MRTF/SRF in CAP2-dependent dilated cardiomyopathy delays disease onset. / 21.03.2019 / PubMed / Full text
MDK
- A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text
AKTIP
- Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits. / 08.2018 / PubMed / Full text
SPRTN
- Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging. / 03.09.2020 / PubMed / Full text
SENP1
- Aging-related SUMOylation pattern in the cortex and blood plasma of wild type mice. / 06.03.2018 / PubMed / Full text
IL1R2
- Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin. / 01.2018 / PubMed / Full text
CXCR6
- CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4 T-Cell-Dependent Control of Senescence. / 05.2019 / PubMed / Full text
CD48
- Genetic overexpression of COMP-Ang1 impairs BM microenvironment and induces senescence of BM HSCs. / 15.05.2018 / PubMed / Full text
GATA1
- Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass. / 10.2019 / PubMed / Full text
MPHOSPH6
- Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text
CXCL17
- [Age-related aspects of the involvement of heat shock proteins in the pathogenesis of osteoarthritis]. / 2017 / PubMed
ATF3
- ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. / 04.2018 / PubMed / Full text
NRL
- Development of a cyclophosphamide stress test to predict resilience to aging in mice. / 12.2020 / PubMed / Full text
SCO1
- Real-Time PCR Analysis of Metabolism-Related Genes in a Long-Lived Model of C. elegans. / 2020 / PubMed / Full text
KLF1
- Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis. / 24.08.2018 / PubMed / Full text
MYCN
- Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells. / 2020 / PubMed / Full text
ARL13B
- ARL13B, a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments. / 20.02.2019 / PubMed / Full text
CPNE1
- Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence. / 04.12.2020 / PubMed / Full text
PLN
- An analysis of the costs of treating aged patients in a large clinical hospital in Poland under the pressure of recent demographic trends. / 2020 / PubMed / Full text
POLG2
- An N-Ethyl-N-Nitrosourea (ENU)-Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice. / 03.2019 / PubMed / Full text
REV1
- REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. / 17.11.2020 / PubMed / Full text
AIDA
- Identification of Postharvest Senescence Regulators Through Map-Based Cloning Using Detached Arabidopsis Inflorescences as a Model Tissue. / 2018 / PubMed / Full text
CRBN
- Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity. / 24.04.2020 / PubMed / Full text
LRRC8B
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
SHANK3
- Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background. / 10.10.2018 / PubMed / Full text
SPATS2L
- Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype. / 02.2019 / PubMed / Full text
TAS1R2
- Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. / 18.10.2018 / PubMed / Full text
CYP2C9
- Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. / 12.2017 / PubMed / Full text
TCTA
- Exciplex-Forming Cohost for High Efficiency and High Stability Phosphorescent Organic Light-Emitting Diodes. / 17.01.2018 / PubMed / Full text
DRAM2
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
PCCB
- Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism. / 03.2018 / PubMed / Full text
SCN2A
- Na 1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age. / 09.09.2019 / PubMed / Full text
ARNTL
- Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text
CR2
- Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text
CYP24A1
- Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism. / 22.02.2018 / PubMed / Full text
HAX1
- Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text
NPBWR1
- Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text
FKBP5
- Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk. / 04.06.2019 / PubMed / Full text
GREM2
- Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis. / 12.2019 / PubMed / Full text
GSTA1
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
TNNI1
- Regular aerobic exercise-ameliorated troponin I carbonylation to mitigate aged rat soleus muscle functional recession. / 05.2019 / PubMed / Full text
SMOX
- Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine. / 14.02.2018 / PubMed / Full text
GRK6
- Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity. / 12.2019 / PubMed / Full text
PRM1
MAX
- Validation of the MedUseQ: A Self-Administered Screener for Older Adults to Assess Medication Use Problems. / 10.2019 / PubMed / Full text
LHCGR
- Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats. / 11.10.2020 / PubMed / Full text
LCN2
- Anthropometric and glucometabolic changes in an aged mouse model of lipocalin-2 overexpression. / 01.2019 / PubMed / Full text
ICAM1
- An Inhibitor of Activated Blood Coagulation Factor X Shows Anti-Endothelial Senescence and Anti-Atherosclerotic Effects. / 2019 / PubMed / Full text
DPP6
- A novel structure associated with aging is augmented in the DPP6-KO mouse brain. / 23.11.2020 / PubMed / Full text
PFKFB3
- DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system. / 05.2018 / PubMed / Full text
GPR37
- Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. / 08.2018 / PubMed / Full text
HYOU1
- Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
GUK1
- Characterization of the impact of GMP/GDP synthesis inhibition on replicative lifespan extension in yeast. / 08.2020 / PubMed / Full text
AQP4
- Overexpression of Slit2 improves function of the paravascular pathway in the aging mouse brain. / 10.2018 / PubMed / Full text
ELANE
- Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text
SLC16A7
- Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach. / 23.10.2020 / PubMed / Full text
CD2
- Adaptive NKG2C CD57 Natural Killer Cell and Tim-3 Expression During Viral Infections. / 2018 / PubMed / Full text
ERCC8
- Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts. / 12.2019 / PubMed / Full text
MFSD2A
- Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease. / 20.12.2019 / PubMed / Full text
SDC2
- Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. / 01.10.2017 / PubMed / Full text
ACD
- Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging. / 02.12.2019 / PubMed / Full text
NRARP
- Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing NRARP. / 10.11.2018 / PubMed / Full text
CTNS
- Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading. / 05.2020 / PubMed / Full text
TYK2
- Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. / 04.2018 / PubMed / Full text
GPR158
- RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss. / 23.10.2018 / PubMed / Full text
NPC2
- Attenuation of the Niemann-Pick type C2 disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2. / 08.2018 / PubMed / Full text
RAI1
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
TSHB
- Adipose TSHB in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence. / 2018 / PubMed / Full text
ABCG5
- 2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. / 01.04.2019 / PubMed / Full text
SOS1
- Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via IRS1/GRB2/ SOS1, GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice. / 21.01.2019 / PubMed / Full text
SLC30A1
- Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text
NDUFS1
- Mapping the protein phosphorylation sites in human mitochondrial complex I (NADH: Ubiquinone oxidoreductase): A bioinformatics study with implications for brain aging and neurodegeneration. / 01.2019 / PubMed / Full text
SELENOV
- The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text
PRMT1
- Reactive oxygen species extend insect life span using components of the insulin-signaling pathway. / 12.09.2017 / PubMed / Full text
HAS2
- Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. / 01.2018 / PubMed / Full text
KDM2B
- Identification of Structural Elements of the Lysine Specific Demethylase 2B CxxC Domain Associated with Replicative Senescence Bypass in Primary Mouse Cells. / 06.2020 / PubMed / Full text
ITGB1
- Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report. / 05.2018 / PubMed / Full text
EFEMP1
- A novel age-related venous amyloidosis derived from EGF-containing fibulin-like extracellular matrix protein 1. / 04.2019 / PubMed / Full text
S100A12
- Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model. / 06.07.2018 / PubMed / Full text
ATG10
PSMG1
- Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. / 03.2018 / PubMed / Full text
NDRG1
- Cx43 phosphorylation-mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein NDRG1. / 02.08.2019 / PubMed / Full text
AP2B1
- Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice. / 20.12.2019 / PubMed / Full text
UGT2B28
- Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a UGT2B28 genomic variation. / 05.12.2019 / PubMed / Full text
PTGS2
- Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. / 21.05.2019 / PubMed / Full text
MCM5
LAMA2
- [Alu insertion-deletion polymorphism of COL13A1 and LAMA2 genes: The analysis of association with longevity]. / 10.2016 / PubMed
ACVR1
- Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome. / 2019 / PubMed / Full text
VASP
- Reversal of Aging-Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein-Protein Interfaces. / 18.07.2018 / PubMed / Full text
PPM1A
- The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1. / 03.08.2019 / PubMed / Full text
RNF13
- The effects of environmental stressors on candidate aging associated genes. / 08.2020 / PubMed / Full text
VSIG4
- Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue. / 10.2020 / PubMed / Full text
AMHR2
- Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. / 03.2018 / PubMed / Full text
ATP6V1E1
- Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text
TGDS
- The evaluation and design of a short depression screening tool in Turkish older adults. / 10.2018 / PubMed / Full text
CDKN1C
- Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text
CXCL14
EWSR1
- EWSR1, a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways. / 01.07.2019 / PubMed / Full text
RNF10
- Reduced RING finger protein 10 expression in macrophages is associated with aging-related inflammation. / 28.11.2020 / PubMed / Full text
SMO
- Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text
ERCC2
- The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text
NDRG2
- NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain. / 04.01.2020 / PubMed / Full text
AMFR
- Mice heterozygous for the Cdh23/Ahl1 mutation show age-related deficits in auditory temporal processing. / 09.2019 / PubMed / Full text
DES
- Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis. / 20.03.2018 / PubMed / Full text
UBB
- Different Expression Levels of Human Mutant Ubiquitin B (UBB ) Can Modify Chronological Lifespan or Stress Resistance of [i]Saccharomyces cerevisiae[/i]. / 2018 / PubMed / Full text
RAD23A
- Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
TSG101
- Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging. / 01.09.2019 / PubMed / Full text
HNRNPA1
- HNRNPA1-mediated 3' UTR length changes of [i]HN1[/i] contributes to cancer- and senescence-associated phenotypes. / 30.06.2019 / PubMed / Full text
ATP2B1
- Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries. / 10.2017 / PubMed / Full text
ANG
- Age-related differences in the cutaneous vascular response to exogenous angiotensin II. / 01.03.2019 / PubMed / Full text
PTPN1
- The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text
GRB10
- De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver. / 05.2018 / PubMed / Full text
BAZ2B
REC8
- Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice. / 10.2018 / PubMed / Full text
LRP6
- Low-density lipoprotein receptor-related protein 6-mediated signaling pathways and associated cardiovascular diseases: diagnostic and therapeutic opportunities. / 04.2020 / PubMed / Full text
TRPV6
- Changes in expression of klotho affect physiological processes, diseases, and cancer. / 01.2018 / PubMed / Full text
VHLL
- The Monetary Valuation of Lifetime Health Improvement and Life Expectancy Gains in Turkey. / 29.09.2017 / PubMed / Full text
POU5F1
- Cell quality evaluation with gene expression analysis of spheroids (3D) and adherent (2D) adipose stem cells. / 24.10.2020 / PubMed / Full text
HDAC10
- Middle-aged female rats lack changes in histone H3 acetylation in the anterior hypothalamus observed in young females on the day of a luteinizing hormone surge. / 17.09.2019 / PubMed / Full text
FDPS
- Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes. / 12.2018 / PubMed / Full text
GDA
- Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces. / 03.2019 / PubMed / Full text
BOC
- Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations. / 01.05.2020 / PubMed / Full text
APLNR
- Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects. / 13.09.2017 / PubMed / Full text
LEF1
- LncRNA H19 targets miR-22 to modulate H O -induced deregulation in nucleus pulposus cell senescence, proliferation, and ECM synthesis through Wnt signaling. / 06.2018 / PubMed / Full text
RHOB
- Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes. / 13.06.2019 / PubMed / Full text
SNAI2
- Reawakening of dormant estrogen-dependent human breast cancer cells by bone marrow stroma secretory senescence. / 17.08.2018 / PubMed / Full text
UCP3
- Integrated study on comparative transcriptome and skeletal muscle function in aged rats. / 01.2018 / PubMed / Full text
APPL1
- Insulin and adipokine signaling and their cross-regulation in postmortem human brain. / 12.2019 / PubMed / Full text
DGCR8
- HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif. / 29.04.2019 / PubMed / Full text
VCL
- The effects of different preservation methods on ide (Leuciscus idus) sperm and the longevity of sperm movement. / 04.2018 / PubMed / Full text
CDH1
- Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation. / 15.09.2020 / PubMed / Full text
GP1BA
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
SMC2
- The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence. / 10.11.2018 / PubMed / Full text
ACADM
- High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats. / 07.2018 / PubMed / Full text
SYT7
- Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells. / 28.02.2019 / PubMed / Full text
ATG4D
- Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats. / 17.07.2019 / PubMed / Full text
CREBBP
- Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. / 22.07.2019 / PubMed / Full text
ADAMTS3
- Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text
IGFBP4
- Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey. / 11.10.2019 / PubMed / Full text
KY
- Combination of acupuncture and Chinese herbal formula for elderly adults with mild cognitive impairment: protocol for a randomized controlled trial. / 11.02.2019 / PubMed / Full text
ANGPT2
- Systemic analysis of gene expression profiles in porcine granulosa cells during aging. / 14.11.2017 / PubMed / Full text
PF4V1
- Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. / 05.2019 / PubMed / Full text
WNK4
- Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2. / 10.2018 / PubMed / Full text
RRM1
- α-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1. / 08.2019 / PubMed / Full text
CINP
- Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging. / 01-03.2019 / PubMed / Full text
NPM1
- Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats. / 29.11.2019 / PubMed / Full text
GRK4
- G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
PRMT8
- Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons. / 29.08.2018 / PubMed / Full text
FADS1
- Aging and FADS1 polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U- C]linoleic acid. / 09.2019 / PubMed / Full text
ATG4B
- Impaired autophagic activity and ATG4B deficiency are associated with increased endoplasmic reticulum stress-induced lung injury. / 27.08.2018 / PubMed / Full text
PSMD13
- Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
PBX1
- Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence. / 10.2020 / PubMed / Full text
PGAP1
- Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text
RBP4
- [Effects of different intensities exercise combined with resveratrol on RBP4 in aged obese rats]. / 08.05.2017 / PubMed / Full text
SAMD12
- Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom. / 05.2018 / PubMed / Full text
RXFP3
- The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage. / 03.12.2019 / PubMed / Full text
CEL
- Nanocarrier-Mediated Chemo-Immunotherapy Arrested Cancer Progression and Induced Tumor Dormancy in Desmoplastic Melanoma. / 28.08.2018 / PubMed / Full text
UBE3A
- Delayed loss of UBE3A reduces the expression of Angelman syndrome-associated phenotypes. / 2019 / PubMed / Full text
SEMA3A
- Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging. / 05.03.2019 / PubMed / Full text
HRH4
- Histamime Receptor H4 as a New Therapeutic Target for Age-related Macular Degeneration. / 11.2016 / PubMed
VPREB3
- Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text
FRG2
- Intergenerational response of steroidogenesis-related genes to maternal malnutrition. / 10.2019 / PubMed / Full text
CYP19A1
- Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model. / 06.2019 / PubMed / Full text
AANAT
- Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis. / 01.06.2019 / PubMed / Full text
ALKBH1
- ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed
NLRC5
- Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians. / 02.02.2018 / PubMed / Full text
CD2AP
- Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text
KIF1B
- BDNF trafficking and signaling impairment during early neurodegeneration is prevented by moderate physical activity. / 12.2016 / PubMed / Full text
CFB
- The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. / 13.06.2018 / PubMed / Full text
ID2
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
ICE1
- ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1. / 19.02.2020 / PubMed / Full text
CPT2
- The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats. / 09.2020 / PubMed / Full text
CAMSAP1
- Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text
SCX
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
SKI
- Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells. / 04.2019 / PubMed / Full text
NKIRAS2
- Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text
XG
- The effect of administration media on palatability and ease of swallowing of multiparticulate formulations. / 15.11.2018 / PubMed / Full text
S100A13
- S100A13 promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α. / 23.01.2019 / PubMed / Full text
MYCNOS
- Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis. / 26.01.2017 / PubMed / Full text
TCF7
- Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice. / 04.2018 / PubMed / Full text
DCTN6
- Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text
HDC
- Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells. / 07.05.2020 / PubMed / Full text
CCL28
- Age-related chemokine alterations affect IgA secretion and gut immunity in female mice. / 10.2020 / PubMed / Full text
GPR19
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
WNT10A
- Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development. / 01.04.2020 / PubMed / Full text
TRBV19
- Perturbed CD8 T cell immunity across universal influenza epitopes in the elderly. / 02.2018 / PubMed / Full text
NPRL3
- KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text
DCLRE1C
- Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population. / 06.2019 / PubMed / Full text
ADNP
- ADNP differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. / 06.2019 / PubMed / Full text
LIFR
- Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. / 15.03.2019 / PubMed / Full text
COQ5
- Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text
MICU1
- Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. / 09.2019 / PubMed / Full text
SRPK1
- [Age-related changes in the content of serine-arginine protein kinase 1 (SRPK1) in human dermis.] / 2017 / PubMed
PCDHGA3
RPTOR
- Endothelial replicative senescence delayed by the inhibition of MTORC1 signaling involves MicroRNA-107. / 08.2018 / PubMed / Full text
MYH10
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
DMPK
- Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans. / 19.04.2019 / PubMed / Full text
IFITM3
- Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3. / 25.06.2019 / PubMed / Full text
TDG
- lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/TDG axis. / 09.2019 / PubMed / Full text
PMS2
- RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text
JAGN1
- Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text
MDN1
MARCKSL1
- MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors. / 04.2018 / PubMed / Full text
CCR3
- Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro. / 04.02.2020 / PubMed / Full text
CD209
- Comparative analysis of microbial sensing molecules in mucosal tissues with aging. / 03.2018 / PubMed / Full text
IL22
- Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text
RICTOR
- Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. / 11.2019 / PubMed / Full text
CDR1
- Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires. / 2018 / PubMed / Full text
PES1
- Transcription factor RD26 is a key regulator of metabolic reprogramming during dark-induced senescence. / 06.2018 / PubMed / Full text
ATF7
- Stress-induced and ATF7-dependent epigenetic change influences cellular senescence. / 09.2019 / PubMed / Full text
NDUFAB1
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
AQP5
- Submandibular gland-specific inflammaging-induced hyposalivation in the male senescence-accelerated mouse prone -1 line (SAM-P1). / 08.2019 / PubMed / Full text
PER3
- Effects of PER3 clock gene polymorphisms on aging-related changes of the cerebral cortex. / 03.2018 / PubMed / Full text
TSPYL5
- Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text
CDC20
- Premature aging syndrome showing random chromosome number instabilities with CDC20 mutation. / 11.2020 / PubMed / Full text
DIP2A
ME1
- NADP-MALIC ENZYME 1 Affects Germination after Seed Storage in Arabidopsis thaliana. / 01.02.2019 / PubMed / Full text
UCHL3
- UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis. / 12.06.2018 / PubMed / Full text
HSD17B4
- Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein-2 deficiency. / 09.2018 / PubMed / Full text
CCL18
- Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text
OLFML3
- Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text
DOCK11
NMS
- Uncontrolled Diabetes as an Associated Factor with Dynapenia in Adults Aged 50 Years or Older: Sex Differences. / 22.05.2020 / PubMed / Full text
AKAP17A
- The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. / 10.2019 / PubMed / Full text
XRCC4
- The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity. / 2018 / PubMed / Full text
DGAT2
- Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
RBM38
- Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating PTEN. / 15.03.2018 / PubMed / Full text
MCM9
- MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors. / 10.09.2019 / PubMed / Full text
IGFBP6
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
AQP2
- A bell-shaped pattern of urinary aquaporin-2-bearing extracellular vesicle release in an experimental model of nephronophthisis. / 05.2019 / PubMed / Full text
CYB5R3
- Overexpression of CYB5R3 and NQO1, two NAD -producing enzymes, mimics aspects of caloric restriction. / 08.2018 / PubMed / Full text
XDH
- Enhancing xanthine dehydrogenase activity is an effective way to delay leaf senescence and increase rice yield. / 11.03.2020 / PubMed / Full text
FEZ1
- Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice. / 19.09.2017 / PubMed / Full text
CD82
- Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis. / 01.11.2018 / PubMed / Full text
IHH
- Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway. / 01.04.2020 / PubMed / Full text
UBC
- Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text
SMARCA5
- The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability. / 13.07.2018 / PubMed / Full text
HCN4
- Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels. / 05.2018 / PubMed / Full text
LAT
- Is the combined auriculotherapy approach superior to magneto-auriculotherapy alone in aging males with lower urinary tract symptoms? A randomized controlled trial. / 16.01.2019 / PubMed / Full text
VGLL4
- The lncRNA MEG3/miR-16-5p/VGLL4 regulatory axis is involved in etoposide-induced senescence of tumor cells. / 03.11.2020 / PubMed / Full text
PDE2A
- TAK-915, a phosphodiesterase 2A inhibitor, ameliorates the cognitive impairment associated with aging in rodent models. / 30.12.2019 / PubMed / Full text
PLCG2
- A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. / 08.2019 / PubMed / Full text
GPR37L1
- Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. / 08.2018 / PubMed / Full text
CSF3R
- Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text
APOC1
- Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text
CCL13
- Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text
PLXNA4
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
KLHL22
- KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text
CES1
- [Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog]. / 2019 / PubMed / Full text
GSTM2
- Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage. / 07.07.2020 / PubMed / Full text
KCNK2
- Brain age prediction using deep learning uncovers associated sequence variants. / 27.11.2019 / PubMed / Full text
ETV5
- miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. / 06.2018 / PubMed / Full text
TLR5
- Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition. / 08.2018 / PubMed / Full text
XPC
- MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene XPC in Age-related Cataract. / 12.10.2018 / PubMed / Full text
HS2ST1
- Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text
IFITM1
- Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection. / 10.11.2018 / PubMed / Full text
PTP4A3
- Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease. / 05.2020 / PubMed / Full text
PDE4C
- Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. / 04.2018 / PubMed / Full text
ARSA
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
PRKAA1
- Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text
CACNA1S
HOXB7
- Impact of HOXB7 overexpression on human adipose-derived mesenchymal progenitors. / 19.03.2019 / PubMed / Full text
CCL19
- Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention. / 16.09.2019 / PubMed / Full text
LAG3
- T Cell Transcriptional Profiling and Immunophenotyping Uncover LAG3 as a Potential Significant Target of Immune Modulation in Multiple Myeloma. / 01.2020 / PubMed / Full text
SFRP2
- [Role and alterations of DNA methylation during the aging and cancer]. / 01.2018 / PubMed / Full text
SYNE1
BACH2
- Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients. / 17.01.2019 / PubMed / Full text
HIRA
CXCR1
- Harmful neutrophil subsets in patients with ischemic stroke: Association with disease severity. / 07.2019 / PubMed / Full text
HIF3A
- Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text
GPR101
- Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent. / 2017 / PubMed / Full text
HDAC11
- Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice. / 19.09.2017 / PubMed / Full text
SRI
- The Role of Aging, Drug Dependence, and Hepatitis C Comorbidity in Alcoholism Cortical Compromise. / 01.05.2018 / PubMed / Full text
GRM2
- Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text
SRM
SLC41A1
- Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis. / 08.05.2019 / PubMed / Full text
SV2C
- Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. / 10.2018 / PubMed / Full text
CCND1
- Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells. / 09.2020 / PubMed / Full text
RAB1B
- Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
CD59
- Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria. / 2019 / PubMed / Full text
SLC1A5
- SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice. / 06.2019 / PubMed / Full text
TP53RK
- Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text
IAPP
- Protein aggregates and proteostasis in aging: Amylin and β-cell function. / 01.2019 / PubMed / Full text
PAX8
- Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging. / 13.09.2019 / PubMed / Full text
GPR173
- Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent. / 2017 / PubMed / Full text
TES
- The Effects of Electrical Stimulation Pulse Duration on Lingual Palatal Pressure Measures During Swallowing in Healthy Older Adults. / 08.2019 / PubMed / Full text
NBN
- G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
IRF5
- Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice. / 11.2017 / PubMed / Full text
NOTCH4
- Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH. / 11.2020 / PubMed / Full text
BMPR1B
- Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes. / 12.2018 / PubMed / Full text
IL9
- Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text
GSTZ1
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
IFI27
- Ultraviolet B irradiation-induced keratinocyte senescence and impaired development of 3D epidermal reconstruct. / 01.06.2021 / PubMed / Full text
ADRA2B
- Aging and the Combined effects of ADRA2B and CB1 deletions on Affective Working Memory. / 11.03.2019 / PubMed / Full text
NCOR2
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
ASPA
- Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. / 04.2018 / PubMed / Full text
SMPD1
- Alterations in Lipid Profile of the Aging Kidney Identified by MALDI Imaging Mass Spectrometry. / 05.07.2019 / PubMed / Full text
GPX3
- Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract. / 2019 / PubMed / Full text
NDN
- The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging. / 2018 / PubMed / Full text
ADAMTS9
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
PRG4
- Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis. / 08.02.2018 / PubMed / Full text
PAFAH2
- Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs. / 03.2019 / PubMed / Full text
CYP3A5
- Effect of Age and Allele Variants of CYP3A5, CYP3A4, and POR Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. / 12.2017 / PubMed / Full text
THEMIS
- Lifetime benefits of early detection and treatment of diabetic kidney disease. / 2019 / PubMed / Full text
FGF6
- Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. / 06.02.2019 / PubMed / Full text
TPP1
- FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping. / 03.11.2020 / PubMed / Full text
IGSF1
- Age-related gene and miRNA expression changes in airways of healthy individuals. / 06.03.2019 / PubMed / Full text
KDM3A
- KDM3A and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization. / 22.11.2019 / PubMed / Full text
HNF4A
- Hepatocyte Nuclear Factor-4α P2 Promoter Variants Are Associated With the Risk of Metabolic Syndrome and Testosterone Deficiency in Aging Taiwanese Men. / 11.2018 / PubMed / Full text
KCNC3
- DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird. / 2017 / PubMed / Full text
JARID2
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
FAH
- Oxaloacetate decarboxylase FAHD1 - a new regulator of mitochondrial function and senescence. / 01.2019 / PubMed / Full text
CHRM4
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
GEN1
- US acculturation and poor sleep among an intergenerational cohort of adult Latinos in Sacramento, California. / 01.03.2019 / PubMed / Full text
PDE4B
- Phosphodiesterase-4B as a Therapeutic Target for Cognitive Impairment and Obesity-Related Metabolic Diseases. / 2017 / PubMed / Full text
TYROBP
PRLR
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
ABHD12
- Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype. / 2019 / PubMed / Full text
RPL37
- Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text
TRPV5
- Changes in expression of klotho affect physiological processes, diseases, and cancer. / 01.2018 / PubMed / Full text
IFT140
TCF15
ANK3
- Age-related atrophy of cortical thickness and genetic effect of ANK3 gene in first episode MDD patients. / 26.08.2020 / PubMed / Full text
MSH6
- RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text
VEGFD
- Single-Arm Resistance Training Study to Determine the Relationship between Training Outcomes and Muscle Growth Factor mRNAs in Older Adults Consuming Numerous Medications and Supplements. / 2018 / PubMed / Full text
LAGE3
- Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text
MFN1
- Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice. / 2018 / PubMed / Full text
ESRG
- MYC Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition. / 10.04.2018 / PubMed / Full text
BCL2L1
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
CDC73
- Down-regulation of cancer-associated gene CDC73 contributes to cellular senescence. / 23.05.2018 / PubMed / Full text
SIL1
- SIL1, the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology. / 10.05.2018 / PubMed / Full text
TGFBR1
- Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text
MMP7
- Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9. / 2018 / PubMed / Full text
CSAD
- The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway. / 19.09.2018 / PubMed / Full text
ERCC6
- Two Cockayne Syndrome patients with a novel splice site mutation - clinical and metabolic analyses. / 10.2018 / PubMed / Full text
DUSP2
- Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism. / 2019 / PubMed / Full text
FOSL2
- LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis. / 03.04.2020 / PubMed / Full text
DDIT3
- Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text
HSPA1L
- Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L-mitophagy pathway. / 03.2020 / PubMed / Full text
RPS6KB1
- Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text
DROSHA
- Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. / 06.2018 / PubMed / Full text
FCGR2A
- Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells. / 03.08.2019 / PubMed / Full text
SERPINA1
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
IL2RA
- Dynamic demethylation of the IL2RA promoter during in vitro CD4+ T cell activation in association with IL2RA expression. / 2018 / PubMed / Full text
AGAP2
- Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2. / 05.08.2019 / PubMed / Full text
U2AF1
- Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs. / 05.03.2020 / PubMed / Full text
SLC19A1
- Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer. / 30.03.2018 / PubMed / Full text
SAA2
- Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells. / 2018 / PubMed / Full text
COL2A1
- Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis. / 08.02.2018 / PubMed / Full text
STC1
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
JAM3
- Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text
NDUFS3
- Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10). / 06.2018 / PubMed / Full text
NPRL2
- KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text
SYT1
- Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins. / 2018 / PubMed / Full text
SERPINB2
- An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through SERPINB2. / 03.07.2019 / PubMed / Full text
EIF2B4
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
LRRC34
- The polygenic nature of telomere length and the anti-ageing properties of lithium. / 03.2019 / PubMed / Full text
ACAD9
- Identification of a novel mitochondrial complex I assembly factor ACDH-12 in Caenorhabditis elegans. / 05.2019 / PubMed / Full text
EXOC7
- PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. / 09.07.2018 / PubMed / Full text
VEGFC
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
KCNE4
- Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice. / 29.05.2018 / PubMed / Full text
TOMM20
- Effect of aging on mitochondria and metabolism of bovine granulosa cells. / 13.09.2020 / PubMed / Full text
ENC1
- Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text
SSBP2
TPX2
- Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells. / 2018 / PubMed / Full text
RBMXL1
BMP7
- Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting BMP7. / 11.12.2019 / PubMed / Full text
CTSL
- Cathepsin L deficiency results in reactive oxygen species (ROS) accumulation and vascular cells activation. / 12.2017 / PubMed / Full text
GRB2
- Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via IRS1/GRB2/ SOS1, GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice. / 21.01.2019 / PubMed / Full text
PLA2R1
- Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes. / 12.2018 / PubMed / Full text
SF1
- Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice. / 15.04.2019 / PubMed / Full text
STOML2
IRGM
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
MORF4L1
- A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text
WWP1
- The ubiquitin ligase WWP1 contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart. / 01.10.2020 / PubMed / Full text
THBS1
- G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
CCAR2
- CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans. / 10.2018 / PubMed / Full text
BRD3
- Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. / 07.2019 / PubMed / Full text
PPP3CB
- Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text
GPX7
- Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7. / 08.2018 / PubMed / Full text
TDP1
- UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis. / 12.06.2018 / PubMed / Full text
NOL12
- NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging. / 15.06.2019 / PubMed / Full text
NMRK2
- Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training. / 2018 / PubMed / Full text
PIP5K1C
- [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text
DCAF17
- Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. / 15.06.2018 / PubMed / Full text
WFDC2
- Differences in biomarkers and molecular pathways according to age for patients with HFrEF. / 01.10.2020 / PubMed / Full text
DSC1
ASB7
- ASB7 Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation. / 2020 / PubMed / Full text
HTRA1
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
KPNA2
- Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice. / 2019 / PubMed / Full text
PRDM16
- Assessment of the Aging of the Brown Adipose Tissue by F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna . / 2018 / PubMed / Full text
EHF
- Extended high frequency hearing and speech perception implications in adults and children. / 11.2020 / PubMed / Full text
SLC26A2
- Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis. / 01.2020 / PubMed / Full text
SLC2A4
- Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text
GGCX
- Multiple Modes of Vitamin K Actions in Aging-Related Musculoskeletal Disorders. / 11.06.2019 / PubMed / Full text
OTX2
- Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice. / 01.03.2018 / PubMed / Full text
DDI2
- Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. / 01.08.2018 / PubMed / Full text
NEIL3
- Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin. / 2019 / PubMed / Full text
GSTP1
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
SCN5A
- [Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug]. / 2018 / PubMed / Full text
FBXO31
- The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence. / 19.10.2018 / PubMed / Full text
ENO1
- Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells. / 2020 / PubMed / Full text
FLT3
NFKB1
- NFKB1 gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation. / 03.2020 / PubMed / Full text
DCTN3
- Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text
MUS81
- Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. / 2019 / PubMed / Full text
DIAPH1
- Diaphanous 1 (DIAPH1) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease. / 2018 / PubMed / Full text
ING1
BAZ1A
- Chromatin remodeling factor BAZ1A regulates cellular senescence in both cancer and normal cells. / 15.07.2019 / PubMed / Full text
NUPR1
- NUPR1 maintains autolysosomal efflux by activating SNAP25 transcription in cancer cells. / 2018 / PubMed / Full text
DNMT3L
- Transient DNMT3L Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast. / 2020 / PubMed / Full text
TFPI
- Identification of cardiovascular health gene variants related to longevity in a Chinese population. / 07.09.2020 / PubMed / Full text
MEST
- Improving specific autobiographical memory in older adults: impacts on mood, social problem solving, and functional limitations. / 09.2018 / PubMed / Full text
CHL1
- Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B. / 07.08.2019 / PubMed / Full text
SFRP1
- [Role and alterations of DNA methylation during the aging and cancer]. / 01.2018 / PubMed / Full text
MIB1
- Immunohistochemical detection of senescence markers in human sarcomas. / 02.2020 / PubMed / Full text
KDM6B
- Histone demethylase KDM6B regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells. / 08.2019 / PubMed / Full text
WNT16
- Inducible [i]Wnt16[/i] inactivation: WNT16 regulates cortical bone thickness in adult mice. / 05.2018 / PubMed / Full text
MYOC
- Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells. / 28.12.2018 / PubMed / Full text
CYP17A1
- Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). / 03.2018 / PubMed / Full text
ADIPOR1
CTSA
- A CTSA-based consultation service to advance research on special and underserved populations. / 16.01.2020 / PubMed / Full text
MYT1
- ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the MYT1-Egln3-Sirt1 Axis. / 01.10.2020 / PubMed / Full text
WASL
PUM1
- Identification of reference genes for RT-qPCR data normalisation in aging studies. / 27.09.2019 / PubMed / Full text
SPG7
- Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration. / 21.02.2018 / PubMed / Full text
FOXC1
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
MARK1
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
EXO1
- Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population. / 06.2019 / PubMed / Full text
CYB5A
RPE65
- Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells. / 08.2018 / PubMed / Full text
CRISPLD2
- A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text
MAPK10
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
CCNA1
- Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. / 02.10.2017 / PubMed / Full text
ZNF521
- Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells. / 21.06.2019 / PubMed / Full text
XPO1
- Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan. / 15.05.2018 / PubMed / Full text
ITGA5
- Kaempferol alleviates the reduction of developmental competence during aging of porcine oocytes. / 11.2019 / PubMed / Full text
IFIH1
- Comparative analysis of microbial sensing molecules in mucosal tissues with aging. / 03.2018 / PubMed / Full text
USP28
- Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program. / 01.10.2017 / PubMed / Full text
KRT19
- Characterization of Krt19 allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc. / 01.2020 / PubMed / Full text
VPS13D
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
EIF2B3
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
SAMD10
- Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text
MERTK
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
GNG4
- Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes. / 05.2018 / PubMed / Full text
TRPM6
MYLPF
- Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. / 15.05.2019 / PubMed / Full text
G6PC
- Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of TP53. / 11.2018 / PubMed / Full text
DNAJB9
- DNAJB9 Inhibits p53-Dependent Oncogene-Induced Senescence and Induces Cell Transformation. / 30.04.2020 / PubMed / Full text
MSRA
- Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis. / 02.2019 / PubMed / Full text
DKK2
- Low Serum Levels of DKK2 Predict Incident Low-Impact Fracture in Older Women. / 07.2019 / PubMed / Full text
CEBPD
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
PPP1R3C
- Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text
VIPR2
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
ITGA2B
- Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. / 04.2018 / PubMed / Full text
IGF2BP3
- Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth. / 01.05.2019 / PubMed / Full text
CRY2
- Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text
TRPC7
- Nociceptive transient receptor potential canonical 7 (TRPC7) mediates aging-associated tumorigenesis induced by ultraviolet B. / 01.2020 / PubMed / Full text
PARK7
- The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text
HBD
- Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection. / 2019 / PubMed / Full text
VPS35
- Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development. / 16.01.2019 / PubMed / Full text
ABCE1
- Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain. / 27.11.2018 / PubMed / Full text
PRDX6
- Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task. / 2019 / PubMed / Full text
RHCG
- Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma. / 06.06.2019 / PubMed / Full text
CREM
- Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells. / 11.2019 / PubMed / Full text
ZFPM2
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
ABCG1
- Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. / 08.2018 / PubMed / Full text
MED25
- The [i]HAC1[/i] histone acetyltransferase promotes leaf senescence and regulates the expression of [i]ERF022[/i]. / 08.2019 / PubMed / Full text
CDKN1B
SELENBP1
- A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity. / 01.2020 / PubMed / Full text
LY6D
- LY6D-induced macropinocytosis as a survival mechanism of senescent cells. / 09.11.2020 / PubMed / Full text
PRKCB
- MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells. / 18.03.2019 / PubMed / Full text
PLD3
SYNJ1
- Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer's Disease. / 05.06.2018 / PubMed / Full text
MYOF
- Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text
SLC7A11
- SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes. / 28.10.2017 / PubMed / Full text
CARM1
- CARM1 regulates senescence during airway epithelial cell injury in COPD pathogenesis. / 01.11.2019 / PubMed / Full text
GPD2
- Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. / 06.2018 / PubMed / Full text
RELB
ARRB2
- Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity. / 12.2019 / PubMed / Full text
THRB
- Age-associated increase of thyroid hormone receptor β gene promoter methylation coexists with decreased gene expression. / 11.2018 / PubMed / Full text
LY86
- Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. / 09.2019 / PubMed / Full text
HAMP
- A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity. / 04.2018 / PubMed / Full text
GSTO1
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
ADH1B
- Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde. / 02.2019 / PubMed / Full text
APOBEC1
- Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology. / 12.12.2017 / PubMed / Full text
DMP1
- Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice. / 07.2018 / PubMed / Full text
AMPH
- Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood. / 01.09.2018 / PubMed / Full text
ILDR1
- Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment. / 23.10.2019 / PubMed / Full text
IGF2R
- Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks. / 05-06.2018 / PubMed / Full text
MCUR1
- Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. / 09.2019 / PubMed / Full text
GLA
- TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25. / 17.05.2018 / PubMed / Full text
JDP2
- Jun dimerization protein 2 controls hypoxia-induced replicative senescence via both the p16 -pRb and Arf-p53 pathways. / 11.2017 / PubMed / Full text
CAPRIN1
- Reduced Levels of the Synaptic Functional Regulator FMRP in Dentate Gyrus of the Aging Sprague-Dawley Rat. / 2017 / PubMed / Full text
DPT
- Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography. / 12.2017 / PubMed / Full text
SLC22A23
- Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease. / 11.2018 / PubMed / Full text
MEFV
PSMD14
- Upregulation of deubiquitinase PSMD14 in lung adenocarcinoma (LUAD) and its prognostic significance. / 2020 / PubMed / Full text
ANK2
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
DSE
- Impact of Intensive Lifestyle Intervention on Disability-Free Life Expectancy: The Look AHEAD Study. / 05.2018 / PubMed / Full text
SUMO1
- SUMO1-conjugation is altered during normal aging but not by increased amyloid burden. / 08.2018 / PubMed / Full text
HBM
- The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis. / 25.09.2019 / PubMed / Full text
ALOX5
- Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme. / 01.01.2020 / PubMed / Full text
PMP22
- Role of microRNAs in senescence and its contribution to peripheral neuropathy in the arsenic exposed population of West Bengal, India. / 02.2018 / PubMed / Full text
SRL
- Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment. / 04-06.2020 / PubMed / Full text
VAMP8
- NUPR1 maintains autolysosomal efflux by activating SNAP25 transcription in cancer cells. / 2018 / PubMed / Full text
PSMD11
- The effect and mechanism of 19S proteasome PSMD11/Rpn6 subunit in D-Galactose induced mimetic aging models. / 01.09.2020 / PubMed / Full text
GALC
- Analysis of age-related changes in psychosine metabolism in the human brain. / 2018 / PubMed / Full text
HNRNPM
- The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. / 10.2019 / PubMed / Full text
FZD4
- MiR-1292 Targets FZD4 to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway. / 12.2018 / PubMed / Full text
GNE
- Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2 mice. / 10.12.2020 / PubMed / Full text
DCTN2
- Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text
ETV6
- FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence. / 01.2019 / PubMed / Full text
DRD4
- ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children. / 04.2019 / PubMed / Full text
FANCC
- Fanconi Anemia complementation group C protein in metabolic disorders. / 21.06.2018 / PubMed / Full text
CALR
- Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender. / 10.2017 / PubMed / Full text
ITGB2
- A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. / 2019 / PubMed / Full text
NKX6-1
SMN2
- Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. / 01.11.2019 / PubMed / Full text
FOXL2
- Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor. / 09.03.2018 / PubMed / Full text
PPP2R1A
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
SOX11
- A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress. / 10.08.2017 / PubMed / Full text
EDEM1
- Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
GCNT2
- Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text
CRYAB
- Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells. / 28.12.2018 / PubMed / Full text
ESR1
- Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement. / 05.01.2018 / PubMed / Full text
ADD2
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
DLL4
- Dynamic regulation of NOTCH1 activation and Notch ligand expression in human thymus development. / 13.08.2018 / PubMed / Full text
TLR6
- Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection. / 05.2018 / PubMed / Full text
TNP1
ACTA2
- Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. / 2018 / PubMed / Full text
LGI1
- Antibody-associated CNS syndromes without signs of inflammation in the elderly. / 03.10.2017 / PubMed / Full text
AKT3
- Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma. / 10.2018 / PubMed / Full text
NKAP
- NKAP Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors. / 2019 / PubMed / Full text
FOXP4
- Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization. / 06.11.2018 / PubMed / Full text
RPL13
- Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text
NACA
- Age and Sex Are Strongly Correlated to the Rate and Type of Mountain Injuries Requiring Search and Rescue Missions. / 12.2019 / PubMed / Full text
FAM13A
- Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. / 05.2018 / PubMed / Full text
FBN2
- Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging. / 26.10.2018 / PubMed / Full text
ADRA2A
- α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway. / 2020 / PubMed / Full text
HPSE
- Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin. / 07.2020 / PubMed / Full text
QRFPR
- Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text
MCM8
- Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. / 2017 / PubMed / Full text
LGR6
- Effect of defensins-containing eye cream on periocular rhytids and skin quality. / 08.2020 / PubMed / Full text
NLRP12
- Persistent DNA damage-induced NLRP12 improves hematopoietic stem cell function. / 21.05.2020 / PubMed / Full text
DAPK2
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
HLA-DQA1
COL13A1
- [Alu insertion-deletion polymorphism of COL13A1 and LAMA2 genes: The analysis of association with longevity]. / 10.2016 / PubMed
CABLES1
- CABLES1 Deficiency Impairs Quiescence and Stress Responses of Hematopoietic Stem Cells in Intrinsic and Extrinsic Manners. / 13.08.2019 / PubMed / Full text
CCND2
- Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma. / 10.2018 / PubMed / Full text
CD226
- T-cell Immunoglobulin and ITIM Domain Contributes to CD8 T-cell Immunosenescence. / 04.2018 / PubMed / Full text
ACAD10
- Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text
DSPP
- Effects of [i]p[/i]-Cresol on Senescence, Survival, Inflammation, and Odontoblast Differentiation in Canine Dental Pulp Stem Cells. / 21.09.2020 / PubMed / Full text
POLR3A
- Nucleolar disruption, activation of P53 and premature senescence in POLR3A-mutated Wiedemann-Rautenstrauch syndrome fibroblasts. / 12.2020 / PubMed / Full text
RCAN1
- Mitochondrial dysfunction and endoplasmic reticulum stress involved in oocyte aging: an analysis using single-cell RNA-sequencing of mouse oocytes. / 08.06.2019 / PubMed / Full text
PCCA
- Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism. / 03.2018 / PubMed / Full text
GABARAP
- Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. / 18.08.2020 / PubMed / Full text
TIMP2
- The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma. / 2019 / PubMed / Full text
DSCAM
- Age- and speed-dependent modulation of gaits in DSCAM mutant mice. / 01.02.2018 / PubMed / Full text
SESN3
- Autophagy mediators (FOXO1, SESN3 and TSC2) in Lewy body disease and aging. / 25.09.2018 / PubMed / Full text
GPR6
- Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy. / 22.09.2020 / PubMed / Full text
NR3C1
- Glucocorticoid receptor (NR3C1) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians. / 02.2019 / PubMed / Full text
CHSY1
- Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in [i]skt[/i] Mice. / 01.2020 / PubMed / Full text
RAD50
- Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells. / 01.09.2018 / PubMed / Full text
INPP5A
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
GREM1
- GREM1 inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. / 09.03.2020 / PubMed / Full text
TLR8
- TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy. / 08.01.2019 / PubMed / Full text
HSPA13
APOA1
- Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I. / 08.2018 / PubMed / Full text
MICA
- Derivation and Validation of a Geriatric-Sensitive Perioperative Cardiac Risk Index. / 16.11.2017 / PubMed / Full text
HOXC4
- Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text
VAMP2
- Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission. / 01.08.2018 / PubMed / Full text
RTN4
SGK1
- Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells. / 05.2020 / PubMed / Full text
HDAC8
- Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri. / 09.2018 / PubMed / Full text
UMOD
- The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. / 03.2019 / PubMed / Full text
DRAM1
- Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. / 12.2019 / PubMed / Full text
SELENOH
- The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text
CASK
- Integrated study on comparative transcriptome and skeletal muscle function in aged rats. / 01.2018 / PubMed / Full text
ARHGAP18
- Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma / 18.11.2019 / PubMed / Full text
GSTK1
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
HOXD8
- Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts. / 2020 / PubMed / Full text
ABL1
- European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia. / 04.2020 / PubMed / Full text
TSHR
- TSH-independent release of thyroid hormones through cold exposure in aging rats. / 27.10.2017 / PubMed / Full text
AACS
- Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study. / 07.11.2020 / PubMed / Full text
POU3F2
- POU3F2 participates in cognitive function and adult hippocampal neurogenesis via mammalian-characteristic amino acid repeats. / 02.2018 / PubMed / Full text
SMC4
- The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence. / 10.11.2018 / PubMed / Full text
VCP
ADCK1
- Functional analysis of Aarf domain-containing kinase 1 in Drosophila melanogaster. / 09.2019 / PubMed / Full text
MPL
- Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender. / 10.2017 / PubMed / Full text
NOBOX
- Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. / 18.10.2017 / PubMed / Full text
MUL1
- Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models. / 28.05.2019 / PubMed / Full text
HRG
- Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice. / 10.2017 / PubMed / Full text
ADK
- Deletion of pancreatic β-cell adenosine kinase improves glucose homeostasis in young mice and ameliorates streptozotocin-induced hyperglycaemia. / 07.2019 / PubMed / Full text
SPON1
- APOE influences working memory in non-demented elderly through an interaction with SPON1 rs2618516. / 07.2018 / PubMed / Full text
EPG5
- Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom. / 05.2018 / PubMed / Full text
SLC39A6
- Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text
SLC22A14
- Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text
DLL1
- MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting DLL1 and Regulating PI3K/AKT Pathway. / 2018 / PubMed / Full text
HOXA3
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
OCLN
- Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats. / 17.07.2019 / PubMed / Full text
DTL
- Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells. / 2018 / PubMed / Full text
SENP6
- Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses. / 10.2020 / PubMed / Full text
GHSR
- The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text
SRD5A2
- Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II. / 11.2020 / PubMed / Full text
KIF1A
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
GSTT2
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
HOXA4
- Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes. / 10.2019 / PubMed / Full text
SOX4
- Age-induced accumulation of methylmalonic acid promotes tumour progression. / 09.2020 / PubMed / Full text
DAZL
- DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions. / 30.10.2018 / PubMed / Full text
RBM25
- HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif. / 29.04.2019 / PubMed / Full text
VEGFA
- APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease. / 03.2020 / PubMed / Full text
SRSF1
- Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome. / 09.2018 / PubMed / Full text
MYO1F
- A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. / 2019 / PubMed / Full text
CXCL13
- RNA-seq data from C-X-C chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype. / 08.2020 / PubMed / Full text
SURF1
- Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice. / 08.2018 / PubMed / Full text
MUC7
- Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model. / 24.09.2019 / PubMed / Full text
DHRS2
- Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts. / 08.05.2018 / PubMed / Full text
RPL4
- Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
BMP6
- Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology. / 06.11.2018 / PubMed / Full text
ABI3BP
- Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing ABI3BP in gallbladder cancer cells. / 07.06.2019 / PubMed / Full text
AIF1
- Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text
USP30
- Deficiency of parkin and PINK1 impairs age-dependent mitophagy in [i]Drosophila[/i]. / 29.05.2018 / PubMed / Full text
SPHK2
- Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. / 04.2019 / PubMed / Full text
ITGAM
- Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging. / 2019 / PubMed / Full text
PRR9
- Circadian control of [i]ORE1[/i] by PRR9 positively regulates leaf senescence in [i]Arabidopsis[/i]. / 14.08.2018 / PubMed / Full text
PIK3R2
- The senescent status of endothelial cells affects proliferation, inflammatory profile and SOX2 expression in bone marrow-derived mesenchymal stem cells. / 06.2019 / PubMed / Full text
MAVS
- Spontaneous activation of a MAVS-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes. / 10.2017 / PubMed / Full text
FNTA
PRDM1
- Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients. / 17.01.2019 / PubMed / Full text
ADAR
- Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. / 09.2018 / PubMed / Full text
CD55
- Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia. / 15.11.2018 / PubMed / Full text
HMGA1
- Characterization of [i]HMGA1P6[/i] transgenic mouse embryonic fibroblasts. / 09.2020 / PubMed / Full text
IL6ST
- The senescent status of endothelial cells affects proliferation, inflammatory profile and SOX2 expression in bone marrow-derived mesenchymal stem cells. / 06.2019 / PubMed / Full text
MMP14
- Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells. / 12.2017 / PubMed / Full text
ANPEP
- Aminopeptidase N expression in the endometrium could affect endometrial receptivity. / 25.06.2019 / PubMed / Full text
CAV1
- Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine. / 24.04.2019 / PubMed / Full text
RIPK2
MAPK8
- Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text
GJC2
- Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging. / 10.2020 / PubMed / Full text
OSGEP
- Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text
KIFC3
- Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging. / 08.2018 / PubMed / Full text
BMPR2
RGS2
- Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone. / 01.05.2019 / PubMed / Full text
KRT18
- Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
IL15
- Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of IL15. / 27.04.2020 / PubMed / Full text
PRKG1
- Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis. / 15.07.2018 / PubMed / Full text
GDF5
- An embryonic CaVβ1 isoform promotes muscle mass maintenance via GDF5 signaling in adult mouse. / 06.11.2019 / PubMed / Full text
SLC15A1
- Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing. / 02.2019 / PubMed / Full text
WAS
- Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number. / 09.11.2017 / PubMed / Full text
VPS13C
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
EPHA1
CDO1
- The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway. / 19.09.2018 / PubMed / Full text
WDR5
- Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16 . / 11.2019 / PubMed / Full text
SHD
- Does self-reported hearing difficulty decrease older adults' cognitive and physical functioning? The mediating role of social isolation. / 11.2020 / PubMed / Full text
SEMA6C
- Suppression of SEMA6C promotes preantral follicles atresia with decreased cell junctions in mice ovaries. / 04.2019 / PubMed / Full text
TCF21
- Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3. / 22.06.2018 / PubMed / Full text
USP14
- Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text
MS4A4E
- Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text
PIM1
- PIM1-catalyzed CBX8 phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast. / 27.06.2018 / PubMed / Full text
CHAT
- Satisfaction and Technology Evaluation of a Telehealth Robotic Program to Optimize Healthy Independent Living for Older Adults. / 11.2018 / PubMed / Full text
EIF2B5
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
RAD9A
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
TRPS1
- miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence. / 01.2020 / PubMed / Full text
RIF1
- 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. / 02.01.2020 / PubMed / Full text
DAP
- Examining changes in the equity of physician distribution in Japan: a specialty-specific longitudinal study. / 08.01.2018 / PubMed / Full text
GATA6
DUT
- Simultaneous liquefaction, saccharification, and fermentation of L-lactic acid using aging paddy rice with hull by an isolated thermotolerant Enterococcus faecalis DUT1805. / 09.2020 / PubMed / Full text
ANXA1
- Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging. / 26.10.2018 / PubMed / Full text
ADORA2B
- Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss. / 12.2020 / PubMed / Full text
LAMA5
- The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. / 05.06.2018 / PubMed / Full text
LYG1
- Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text
TET3
- Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords. / 02.2019 / PubMed / Full text
MARCKS
- Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. / 07-08.2018 / PubMed / Full text
PIK3R1
- Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. / 08.10.2018 / PubMed / Full text
GJA8
CHRNA7
- Associations between genetic variations and global motion perception. / 10.2019 / PubMed / Full text
LDB2
- Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text
WNT3
CDX2
- Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. / 08.07.2019 / PubMed / Full text
RIMS2
- Age-related gene and miRNA expression changes in airways of healthy individuals. / 06.03.2019 / PubMed / Full text
P4HA2
- Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients. / 03.09.2019 / PubMed / Full text
SLC30A10
- Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text
ERAP1
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
SLC30A5
- Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text
PTPRC
- Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text
NPW
- Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study. / 09.2020 / PubMed / Full text
NLRP6
- LRP6 targeting suppresses gastric tumorigenesis via P14 -Mdm2-P53-dependent cellular senescence. / 19.12.2017 / PubMed / Full text
SCNN1B
- Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. / 18.10.2018 / PubMed / Full text
SP2
- Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography. / 12.2017 / PubMed / Full text
SESN1
- Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis. / 09.2018 / PubMed / Full text
ISG15
- Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood. / 14.01.2019 / PubMed / Full text
RAG2
- Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation. / 2020 / PubMed / Full text
ECM1
- Novel role of extracellular matrix protein 1 (ECM1) in cardiac aging and myocardial infarction. / 2019 / PubMed / Full text
ROS1
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
TAF7L
- Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. / 22.01.2020 / PubMed / Full text
TCERG1
- The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity. / 17.07.2019 / PubMed / Full text
RPIA
- Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming. / 20.08.2019 / PubMed / Full text
ACO1
- Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine. / 24.04.2019 / PubMed / Full text
HLA-DRB1
- The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle. / 11.2020 / PubMed / Full text
LOXL1
- A blackberry-dill extract combination synergistically increases skin elasticity. / 10.2020 / PubMed / Full text
CYP11B2
- Expression of aldosterone synthase CYP11B2 was inversely correlated with longevity. / 07.2019 / PubMed / Full text
CDH2
- CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type. / 30.11.2018 / PubMed / Full text
STX17
- Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and XIAP. / 01.10.2019 / PubMed / Full text
CNTNAP2
- Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text
RGS14
- Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. / 08.2018 / PubMed / Full text
RHEBL1
- Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. / 03.2018 / PubMed / Full text
FCER1G
- A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. / 2019 / PubMed / Full text
PMS1
- RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text
TXNRD1
- The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text
ITPR2
- The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling. / 12.2018 / PubMed / Full text
KAT6B
- Aging-associated decrease in the histone acetyltransferase KAT6B is linked to altered hematopoietic stem cell differentiation. / 02.2020 / PubMed / Full text
ASB3
- Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype. / 02.2019 / PubMed / Full text
F12
- Multigenerational effects of carbendazim in Daphnia magna: From a subcellular to a population level. / 02.2019 / PubMed / Full text
MAL
- Daylight photodynamic therapy versus cryosurgery for the treatment and prophylaxis of actinic keratoses of the face - protocol of a multicenter, prospective, randomized, controlled, two-armed study. / 25.10.2017 / PubMed / Full text
CEBPB
- Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text
UNG
- UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans. / 01.05.2018 / PubMed / Full text
PHB2
- Prohibitin-2 is a novel regulator of p21 induced by depletion of γ-glutamylcyclotransferase. / 29.01.2018 / PubMed / Full text
DBT
- Diurnal rhythms of heart and respiratory rates in donkeys of different age groups during the cold-dry and hot-dry seasons in a tropical savannah. / 09.2018 / PubMed / Full text
SUGCT
- Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype. / 09.2020 / PubMed / Full text
HK2
- Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury. / 11.01.2018 / PubMed / Full text
ATP1A2
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
ITGA6
- Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text
EDF1
- Silencing of FOREVER YOUNG FLOWER Like Genes from Phalaenopsis Orchids Promotes Flower Senescence and Abscission. / 25.11.2020 / PubMed / Full text
DOT1L
- Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. / 04.2018 / PubMed / Full text
DAXX
- ATRX-DAXX Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains. / 09.2019 / PubMed / Full text
GLO1
S100A6
- Sex differences in distribution of cannabinoid receptors (CB1 and CB2), S100A6 and CacyBP/SIP in human ageing hearts. / 27.11.2018 / PubMed / Full text
PGM1
- Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. / 15.05.2019 / PubMed / Full text
TARDBP
- Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice. / 06.2018 / PubMed / Full text
ANKS1B
- Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text
DNM1
- Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice. / 2018 / PubMed / Full text
LYST
GFRAL
- Growth differentiation factor 15 (GDF15): A survival protein with therapeutic potential in metabolic diseases. / 06.2019 / PubMed / Full text
UHRF1
COQ9
- Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text
SLC52A2
- Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. / 01.11.2017 / PubMed / Full text
PRDM8
- PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation. / 20.08.2020 / PubMed / Full text
F10
- Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-F10 cells by inducing senescence. / 15.07.2018 / PubMed / Full text
DNM2
- Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy. / 19.11.2018 / PubMed / Full text
PSAP
- Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. / 08.2018 / PubMed / Full text
TRIM21
- TRIM21 overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma. / 2020 / PubMed / Full text
TMEM119
- Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text
CDC6
- A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence. / 10.01.2018 / PubMed / Full text
RPL11
- NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging. / 15.06.2019 / PubMed / Full text
EED
PAX1
- Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text
FER1L6
- Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text
KDM5A
- Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines. / 15.01.2019 / PubMed / Full text
CYP11B1
- Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼. / 11.2020 / PubMed / Full text
ALAS1
- Heterozygous disruption of ALAS1 in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver. / 08.12.2020 / PubMed / Full text
TRAP1
- Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
ASIP
- Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation. / 10.2018 / PubMed / Full text
MSH2
- RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text
SMC3
- Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice. / 10.2018 / PubMed / Full text