Aging genes 70-79

TERT[править]

Telomeres and telomerase in risk assessment of cardiovascular diseases. / 15.12.2020 / PubMed / Full text
A 4-Base-Pair Core-Enclosing Helix in Telomerase RNA Is Essential for Activity and for Binding to the Telomerase Reverse Transcriptase Catalytic Protein Subunit. / 20.11.2020 / PubMed / Full text
Angiotensin inhibition and cellular senescence in the developing rat kidney. / 12.2020 / PubMed / Full text
Decreased expression of TERT and telomeric proteins as human ovaries age may cause telomere shortening. / 27.08.2020 / PubMed / Full text
The secrets of telomerase: Retrospective analysis and future prospects. / 15.09.2020 / PubMed / Full text
Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides. / 06.2020 / PubMed / Full text
Unravelling Cellular Mechanisms of Stem Cell Senescence: An Aid from Natural Bioactive Molecules. / 20.03.2020 / PubMed / Full text
Expression of telomerase reverse transcriptase positively correlates with duration of lithium treatment in bipolar disorder. / 04.2020 / PubMed / Full text
FAM96B inhibits the senescence of dental pulp stem cells. / 05.2020 / PubMed / Full text
Aging and biomarkers: Transcriptional levels evaluation of Osteopontin/miRNA-181a axis in hepatic tissue of rats in different age ranges. / 05.2020 / PubMed / Full text
Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells. / 04.2020 / PubMed / Full text
Characterization of human telomerase reverse transcriptase immortalized anterior cruciate ligament cell lines. / 12.2019 / PubMed / Full text
Mitochondria, Telomeres and Telomerase Subunits. / 2019 / PubMed / Full text
Towards Therapeutic Alternatives for Mercury Neurotoxicity in the Amazon: Unraveling the Pre-Clinical Effects of the Superfruit Açaí ([i]Euterpe oleracea[/i], Mart.) as Juice for Human Consumption. / 26.10.2019 / PubMed / Full text
Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing. / 08.10.2019 / PubMed / Full text
Telomerase Biology Associations Offer Keys to Cancer and Aging Therapeutics. / 2020 / PubMed / Full text
Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts. / 17.09.2019 / PubMed / Full text
Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants. / 12.2019 / PubMed / Full text
TERT assists GDF11 to rejuvenate senescent VEGFR2 /CD133 cells in elderly patients with myocardial infarction. / 11.2019 / PubMed / Full text
Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with Epigenetics. / 07.07.2019 / PubMed / Full text
Role of Senescence and Neuroprotective Effects of Telomerase in Neurodegenerative Diseases. / 04.2020 / PubMed / Full text
Telomerase reverse transcriptase ameliorates lung fibrosis by protecting alveolar epithelial cells against senescence. / 31.05.2019 / PubMed / Full text
Analysis of the Association Between [i]TERC[/i] and [i]TERT[/i] Genetic Variation and Leukocyte Telomere Length and Human Lifespan-A Follow-Up Study. / 25.01.2019 / PubMed / Full text
Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. / 23.01.2019 / PubMed / Full text
Tissue iron is negatively correlated with TERC or TERT mRNA expression: A heterochronic parabiosis study in mice. / 16.12.2018 / PubMed / Full text
Cell cycle-dependent and -independent telomere shortening accompanies murine brain aging. / 20.11.2018 / PubMed / Full text
Extended proliferation of chicken- and Okinawa rail-derived fibroblasts by expression of cell cycle regulators. / 05.2019 / PubMed / Full text
The Telomerase Complex Directly Controls Hematopoietic Stem Cell Differentiation and Senescence in an Induced Pluripotent Stem Cell Model of Telomeropathy. / 2018 / PubMed / Full text
Clinical Implications of Clonal Hematopoiesis. / 08.2018 / PubMed / Full text
Contact-independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis. / 09.2018 / PubMed / Full text
Possible association of the TERT promoter polymorphisms rs2735940, rs7712562 and rs2853669 with diabetes mellitus in obese elderly Polish population: results from the national PolSenior study. / 08.2018 / PubMed / Full text
Telomerase May Paradoxically Accelerate Aging of the DNA Methylome. / 04.2018 / PubMed / Full text
Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. / 05.2018 / PubMed / Full text
GWAS of epigenetic aging rates in blood reveals a critical role for TERT. / 26.01.2018 / PubMed / Full text
Curcumin Affects Adipose Tissue-Derived Mesenchymal Stem Cell Aging Through TERT Gene Expression. / 04.2018 / PubMed / Full text
Rat adipose-derived mesenchymal stem cells aging reduction by zinc sulfate under extremely low frequency electromagnetic field exposure is associated with increased telomerase reverse transcriptase gene expression. / Spring.2017 / PubMed / Full text
Accelerated cellular senescence as underlying mechanism for functionally impaired bone marrow-derived progenitor cells in ischemic heart disease. / 05.2017 / PubMed / Full text
Cinnamaldehyde and eugenol change the expression folds of AKT1 and DKC1 genes and decrease the telomere length of human adipose-derived stem cells (hASCs): An experimental and in silico study. / 03.2017 / PubMed / Full text
Immortalized prairie vole-derived fibroblasts (VMF-K4DTs) can be transformed into pluripotent stem cells and provide a useful tool with which to determine optimal reprogramming conditions. / 21.06.2017 / PubMed / Full text
Comprehensive Analysis of Interaction Networks of Telomerase Reverse Transcriptase with Multiple Bioinformatic Approaches: Deep Mining the Potential Functions of Telomere and Telomerase. / 08.2017 / PubMed / Full text
Differential decrease in soluble and DNA-bound telomerase in senescent human fibroblasts. / 08.2017 / PubMed / Full text
Sex-dependent telomere shortening, telomerase activity and oxidative damage in marine medaka Oryzias melastigma during aging. / 30.11.2017 / PubMed / Full text
Autophagy induction reduces telomerase activity in HeLa cells. / 04.2017 / PubMed / Full text
Common variants of human TERT and TERC genes and susceptibility to sporadic Alzheimers disease. / 02.2017 / PubMed / Full text
Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing. / 14.02.2017 / PubMed / Full text
Regulation of the Human Telomerase Gene TERT by Telomere Position Effect-Over Long Distances (TPE-OLD): Implications for Aging and Cancer. / 12.2016 / PubMed / Full text
Targeting of multiple senescence-promoting genes and signaling pathways by triptonide induces complete senescence of acute myeloid leukemia cells. / 15.02.2017 / PubMed / Full text
Increased Telomerase Reverse Transcriptase Expression Associates with Spontaneous Exit from M-II Arrest in Rat Eggs. / 02.2017 / PubMed / Full text
Low p16 Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone. / 03.2017 / PubMed / Full text
Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria. / 22.10.2016 / PubMed / Full text
Telomere length is regulated by FGF-2 in human embryonic stem cells and affects the life span of its differentiated progenies. / 02.2017 / PubMed / Full text
Role of Telomerase in the Cardiovascular System. / 17.06.2016 / PubMed / Full text
Stimulation of cell proliferation by glutathione monoethyl ester in aged bone marrow stromal cells is associated with the assistance of TERT gene expression and telomerase activity. / 08.2016 / PubMed / Full text
Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations. / 02.06.2016 / PubMed / Full text
Neuroprotective effects of the catalytic subunit of telomerase: A potential therapeutic target in the central nervous system. / 07.2016 / PubMed / Full text
Clinical Characteristics and Prognostic Significance of TERT Promoter Mutations in Cancer: A Cohort Study and a Meta-Analysis. / 2016 / PubMed / Full text
[Vitamin C promotes in vitro proliferation of bone marrow mesenchymal stem cells derived from aging mice]. / 12.2015 / PubMed
Increased expression of telomere-regulating genes in endurance athletes with long leukocyte telomeres. / 15.01.2016 / PubMed / Full text
A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34 hematopoietic stem cells not reversible by mTOR-inhibition. / 11.2015 / PubMed / Full text
Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs. / 25.12.2015 / PubMed / Full text
Anti-aging effect of estrogen on telomerase activity in ovariectomised rats--animal model for menopause. / 07.2015 / PubMed / Full text
Telomerase activity promotes osteoblast differentiation by modulating IGF-signaling pathway. / 12.2015 / PubMed / Full text
Tissue formation and tissue engineering through host cell recruitment or a potential injectable cell-based biocomposite with replicative potential: Molecular mechanisms controlling cellular senescence and the involvement of controlled transient telomerase activation therapies. / 12.2015 / PubMed / Full text
The impact of immunosenescence on humoral immune response variation after influenza A/H1N1 vaccination in older subjects. / 2015 / PubMed / Full text
Stromal cell-derived factor-1α prevents endothelial progenitor cells senescence and enhances re-endothelialization of injured arteries via human telomerase reverse transcriptase. / 08.2015 / PubMed / Full text
Telomerase redux: ready for prime time? / 04.2015 / PubMed / Full text
Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells. / 05.2015 / PubMed / Full text
Telomere length and the risk of atrial fibrillation: insights into the role of biological versus chronological aging. / 12.2014 / PubMed / Full text
Chronic sleep fragmentation induces endothelial dysfunction and structural vascular changes in mice. / 01.11.2014 / PubMed / Full text
The MNS16A polymorphism in the TERT gene in peri-centenarians from the Han Chinese population. / 10.2014 / PubMed / Full text
Molecular cloning and measurement of telomerase reverse transcriptase (TERT) transcription patterns in tissues of European hake (Merluccius merluccius) and Atlantic cod (Gadus morhua) during aging. / 10.05.2014 / PubMed / Full text
Cellular functions of the dual-targeted catalytic subunit of telomerase, telomerase reverse transcriptase--potential role in senescence and aging. / 08.2014 / PubMed / Full text
Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. / 2013 / PubMed / Full text
Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility. / 14.01.2014 / PubMed / Full text
Extracting extra-telomeric phenotypes from telomerase mouse models. / 01.2014 / PubMed / Full text
Molecular adaptation of telomere associated genes in mammals. / 15.11.2013 / PubMed / Full text
Transplantation of mesenchymal cells rejuvenated by the overexpression of telomerase and myocardin promotes revascularization and tissue repair in a murine model of hindlimb ischemia. / 13.09.2013 / PubMed / Full text
The functional VNTR MNS16A of the TERT gene is associated with human longevity in a population of Central Italy. / 06.2013 / PubMed / Full text
Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity. / 2013 / PubMed / Full text

STAT3[править]

Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice. / 09.2020 / PubMed / Full text
Skeletal glucocorticoid signalling determines leptin resistance and obesity in aging mice. / 12.2020 / PubMed / Full text
FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. / 14.10.2020 / PubMed / Full text
AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF-κB/STAT3 axis-mediated positive feedback loop. / 10.2020 / PubMed / Full text
Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity. / 2020 / PubMed / Full text
Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation. / 08.09.2020 / PubMed / Full text
Cell Death by Gallotannin Is Associated with Inhibition of the JAK/STAT Pathway in Human Colon Cancer Cells. / 2020 / PubMed / Full text
Hepatocyte growth factor (HGF) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling pathways. / 31.07.2020 / PubMed / Full text
The effect of interleukin 6 deficiency on myocardial signal transduction pathways activation induced by bacterial lipopolysaccharide in young and old mice. / 09.2020 / PubMed / Full text
Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression. / 10.2020 / PubMed / Full text
Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients. / 07.06.2020 / PubMed / Full text
Implication of JAK1/STAT3/SOCS3 Pathway in Aging of Cerebellum of Male Rat: Histological and Molecular study. / 01.06.2020 / PubMed / Full text
Atorvastatin-induced senescence of hepatocellular carcinoma is mediated by downregulation of hTERT through the suppression of the IL-6/STAT3 pathway. / 2020 / PubMed / Full text
Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells. / 27.01.2020 / PubMed / Full text
STAT3 Relays a Differential Response to Melanoma-Associated [i]NRAS[/i] Mutations. / 02.01.2020 / PubMed / Full text
Persistent Activation of STAT3 Pathway in the Retina Induced Vision Impairment and Retinal Degenerative Changes in Ageing Mice. / 2019 / PubMed / Full text
The influence of fibroblast growth factor 2 on the senescence of human adipose-derived mesenchymal stem cells during long-term culture. / 04.2020 / PubMed / Full text
Interleukin-10 induces senescence of activated hepatic stellate cells via STAT3-p53 pathway to attenuate liver fibrosis. / 02.2020 / PubMed / Full text
The proteasome activator REGγ counteracts immunoproteasome expression and autoimmunity. / 09.2019 / PubMed / Full text
Sexual dimorphism in rat thymic involution: a correlation with thymic oxidative status and inflammation. / 08.2019 / PubMed / Full text
Inflammaging: Age and Systemic, Cellular, and Nuclear Inflammatory Biology in Older Adults. / 04.10.2019 / PubMed / Full text
A novel STAT3 inhibitor, HJC0152, exerts potent antitumor activity in glioblastoma. / 2019 / PubMed / Full text
Congenital Hypothyroidism is Associated With Impairment of the Leptin Signaling Pathway in the Hypothalamus in Male Wistar Animals in Adult Life. / 05.2019 / PubMed / Full text
mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism. / 06.2019 / PubMed / Full text
[Tea polyphenols delays human glomerular mesangial cells senescence induced by high glucose via regulating STAT3/miR-126/telomere signaling pathway activation]. / 12.2018 / PubMed / Full text
STAT3 Regulates the Onset of Oxidant-induced Senescence in Lung Fibroblasts. / 07.2019 / PubMed / Full text
Deciphering Molecular and Phenotypic Changes Associated with Early Autoimmune Disease in the Aire-Deficient Mouse Model of Sjögren's Syndrome. / 17.11.2018 / PubMed / Full text
Senescent Breast Luminal Cells Promote Carcinogenesis through Interleukin-8-Dependent Activation of Stromal Fibroblasts. / 15.01.2019 / PubMed / Full text
The role of STAT3/mTOR-regulated autophagy in angiotensin II-induced senescence of human glomerular mesangial cells. / 01.2019 / PubMed / Full text
A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. / 2018 / PubMed / Full text
Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model. / 11.09.2018 / PubMed / Full text
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition. / 10.2018 / PubMed / Full text
Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text
Overexpression of Klotho Inhibits HELF Fibroblasts SASP-related Protumoral Effects on Non-small Cell Lung Cancer Cells. / 2018 / PubMed / Full text
Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis. / 01.08.2018 / PubMed / Full text
Age-Associated Differences in Infection of Human Skin in the SCID Mouse Model of Varicella-Zoster Virus Pathogenesis. / 01.06.2018 / PubMed / Full text
MMP2-A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction. / 19.01.2018 / PubMed / Full text
Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia. / 01.01.2018 / PubMed / Full text
Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon. / 2017 / PubMed / Full text
Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text
The pathological roles of NDRG2 in Alzheimer's disease, a study using animal models and APPwt-overexpressed cells. / 08.2017 / PubMed / Full text
Maintenance of membrane organization in the aging mouse brain as the determining factor for preventing receptor dysfunction and for improving response to anti-Alzheimer treatments. / 06.2017 / PubMed / Full text
JAK-STAT signaling mediates the senescence of bone marrow-mesenchymal stem cells from systemic lupus erythematosus patients. / 01.03.2017 / PubMed / Full text
Hypothalamic S1P/S1PR1 axis controls energy homeostasis in Middle-Aged Rodents: the reversal effects of physical exercise. / 26.12.2016 / PubMed / Full text
Intracerebroventricular tempol administration in older rats reduces oxidative stress in the hypothalamus but does not change STAT3 signalling or SIRT1/AMPK pathway. / 01.2017 / PubMed / Full text
STAT3-mediated SMAD3 activation underlies Oncostatin M-induced Senescence. / 16.02.2017 / PubMed / Full text
Impaired Epidermal to Dendritic T Cell Signaling Slows Wound Repair in Aged Skin. / 17.11.2016 / PubMed / Full text
Aging amplifies multiple phenotypic defects in mice with zinc transporter Zip14 (Slc39a14) deletion. / 01.12.2016 / PubMed / Full text
The role of STAT transcription factors in apoptosis regulation of hypothalamic neurons in aging in HER-2/neu transgenic mice and wild-type FVB/N mice. / 05.2016 / PubMed / Full text
Exogenous H2S contributes to recovery of ischemic post-conditioning-induced cardioprotection by decrease of ROS level via down-regulation of NF-κB and JAK2-STAT3 pathways in the aging cardiomyocytes. / 2016 / PubMed / Full text
Enhanced Transcriptional Activity and Mitochondrial Localization of STAT3 Co-induce Axon Regrowth in the Adult Central Nervous System. / 12.04.2016 / PubMed / Full text
The Inflammatory Transcription Factors NFκB, STAT1 and STAT3 Drive Age-Associated Transcriptional Changes in the Human Kidney. / 12.2015 / PubMed / Full text
[Epidermal aging and anti-aging strategies]. / 02.2016 / PubMed / Full text
Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ. / 12.2015 / PubMed / Full text
IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis. / 11.08.2015 / PubMed / Full text
Down-regulation of mir-542-3p promotes neointimal formation in the aging rat. / 09.2015 / PubMed / Full text
CD4⁺CD28null T lymphocytes resemble CD8⁺CD28null T lymphocytes in their responses to IL-15 and IL-21 in HIV-infected patients. / 09.2015 / PubMed / Full text
Constitutive STAT3 activation in epidermal keratinocytes enhances cell clonogenicity and favours spontaneous immortalization by opposing differentiation and senescence checkpoints. / 01.2015 / PubMed / Full text
STAT3 signaling controls satellite cell expansion and skeletal muscle repair. / 10.2014 / PubMed / Full text
Aging impairs transcriptional regulation of vascular endothelial growth factor in human microvascular endothelial cells: implications for angiogenesis and cell survival. / 04.2014 / PubMed
Gene expression profiling of Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly reveals alterations of characteristic oncogenetic pathways. / 05.2014 / PubMed / Full text
STAT3 and metabolism: how many ways to use a single molecule? / 01.11.2014 / PubMed / Full text
Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis. / 21.02.2014 / PubMed / Full text
IL-6-STAT3 signaling and premature senescence. / 01.10.2013 / PubMed / Full text
From cirrhosis to hepatocellular carcinoma: new molecular insights on inflammation and cellular senescence. / 08.2013 / PubMed / Full text
Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination. / 14.01.2014 / PubMed / Full text
Altered methylation and expression of ER-associated degradation factors in long-term alcohol and constitutive ER stress-induced murine hepatic tumors. / 2013 / PubMed / Full text
Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons. / 24.10.2013 / PubMed / Full text
STAT3 as a new autophagy regulator. / 01.07.2013 / PubMed / Full text
Activation of interleukin-6/signal transducer and activator of transcription 3 by human papillomavirus early proteins 6 induces fibroblast senescence to promote cervical tumourigenesis through autocrine and paracrine pathways in tumour microenvironment. / 12.2013 / PubMed / Full text
Hepatoprotective and anti-fibrotic functions of interleukin-22: therapeutic potential for the treatment of alcoholic liver disease. / 08.2013 / PubMed / Full text
An age-related numerical and functional deficit in CD19( ) CD24(hi) CD38(hi) B cells is associated with an increase in systemic autoimmunity. / 10.2013 / PubMed / Full text
Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models. / 09.2013 / PubMed / Full text
Age-dependent germline mosaicism of the most common noonan syndrome mutation shows the signature of germline selection. / 06.06.2013 / PubMed / Full text
Inactivation of JAK2/STAT3 signaling axis and downregulation of M1 mAChR cause cognitive impairment in klotho mutant mice, a genetic model of aging. / 07.2013 / PubMed / Full text
Attenuated expression of gelsolin in association with induction of aquaporin-1 and nitric oxide synthase in dysfunctional hearts of aging mice exposed to endotoxin. / 10-12.2012 / PubMed / Full text

DBP[править]

Blood Pressure in Different Dementia Disorders, Mild Cognitive Impairment, and Subjective Cognitive Decline. / 2020 / PubMed / Full text
Do baseline blood pressure and type of exercise influence level of reduction induced by training in hypertensive older adults? A meta-analysis of controlled trials. / 15.10.2020 / PubMed / Full text
Attenuated aortic blood pressure responses to metaboreflex activation in older adults with dynapenia. / 09.2020 / PubMed / Full text
Association Between Pulsatile Components of Blood Pressure and Severe Tooth Loss in Rural Ecuador: The Three Villages Study. / 01-12.2020 / PubMed / Full text
The Effect of Blood Pressure on Cognitive Performance. An 8-Year Follow-Up of the Tromsø Study, Comprising People Aged 45-74 Years. / 2020 / PubMed / Full text
Low Diastolic Blood Pressure and Cognitive Decline in Korean Elderly People: The Korean Longitudinal Study on Cognitive Aging and Dementia. / 01.2020 / PubMed / Full text
Increased serum salusin-α by aerobic exercise training correlates with improvements in arterial stiffness in middle-aged and older adults. / 09.01.2020 / PubMed / Full text
Diastolic Blood Pressure Is Associated With Regional White Matter Lesion Load: The Northern Manhattan Study. / 02.2020 / PubMed / Full text
Orthostatic Hypotension and Novel Blood Pressure Associated Gene Variants in Older Adults: Data From the TILDA Study. / 15.10.2020 / PubMed / Full text
Blood pressure and hypertension prevalence among oldest-old in China for 16 year: based on CLHLS. / 09.09.2019 / PubMed / Full text
The age-related blood pressure trajectories from young-old adults to centenarians: A cohort study. / 01.12.2019 / PubMed / Full text
Evidence of neurodegeneration in individuals with only mildly elevated blood pressure. / 12.2019 / PubMed / Full text
Upward resetting of the vascular sympathetic baroreflex in middle-aged male runners. / 01.07.2019 / PubMed / Full text
Fruit, vegetable intake and blood pressure trajectories in older age. / 09.2019 / PubMed / Full text
Associations between vitamin D deficiency, musculoskeletal health, and cardiometabolic risk among community-living people in Taiwan: Age and sex-specific relationship. / 12.2018 / PubMed / Full text
Age-differential association between serum uric acid and incident hypertension. / 03.2019 / PubMed / Full text
Effect of phthalates on development, reproduction, fat metabolism and lifespan in Daphnia magna. / 01.03.2019 / PubMed / Full text
The association between urinary sodium excretion and blood pressure in a community-based population: the Yamagata (Takahata) study. / 03.2019 / PubMed / Full text
Differential Associations of Diastolic and Systolic Pressures With Cerebral Measures in Older Individuals With Mild Cognitive Impairment. / 13.11.2018 / PubMed / Full text
Age-related change in thyroid-stimulating hormone: a cross-sectional study in healthy euthyroid population. / 29.11.2018 / PubMed / Full text
[Association between blood pressure related dietary patterns and identified cognitive performance in the elderly Chinese-a study by reduced rank regression method]. / 10.06.2018 / PubMed / Full text
Optimal Blood Pressure in Elderly Hypertensive Subjects: A Korean National Health Insurance Service Health Examinee Cohort Study. / 03.08.2018 / PubMed / Full text
Inter-relationship between ageing, body mass index, diabetes, systemic blood pressure and intraocular pressure in Asians: 6-year longitudinal study. / 02.2019 / PubMed / Full text
Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks. / 05-06.2018 / PubMed / Full text
Association of regular walking and body mass index on metabolic syndrome among an elderly Korean population. / 06.2018 / PubMed / Full text
Blood Pressure Trajectories in the 20 Years Before Death. / 01.01.2018 / PubMed / Full text
Determinants of carotid-femoral pulse wave velocity progression in hypertensive patients over a 3.7 years follow-up. / 02.2018 / PubMed / Full text
Associations between Greenness, Impervious Surface Area, and Nighttime Lights on Biomarkers of Vascular Aging in Chennai, India. / 02.08.2017 / PubMed / Full text
A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers. / 07.2017 / PubMed / Full text
Aging and obesity are associated with undiagnosed hypertension in a cohort of males in the Central Province of Sri Lanka: a cross-sectional descriptive study. / 21.06.2017 / PubMed / Full text
[Metabolic risk factors in patients 60 years and older with arterial hypertension, living in extreme conditions of the Far North]. / 2015 / PubMed
Apolipoprotein C-I Polymorphism and Its Association with Serum Lipid Levels and Longevity in the Bama Population. / 09.05.2017 / PubMed / Full text
Association between serum gamma-glutamyl transferase and serum uric acid levels in Chinese females: A cross-sectional study. / 11.2017 / PubMed / Full text
Interactive Effects of Trait Self-Control and Stress Appraisals on Blood Pressure Responses to a Laboratory Stressor. / 08.2017 / PubMed / Full text
Autonomic cardiac regulation, blood pressure and cardiorespiratory fitness responses to different training doses over a 12 week group program in the elderly. / 05-06.2017 / PubMed / Full text
Paraoxonase-1 (PON1) rs662 Polymorphism and Its Association with Serum Lipid Levels and Longevity in the Bama Zhuang Population. / 27.12.2016 / PubMed / Full text
Association of [i]SIRT6[/i] Gene Polymorphisms with Human Longevity. / 11.2016 / PubMed / Full text
Effect of concurrent resistance and sprint training on body composition and cardiometabolic health indicators in masters cyclists. / 10.2016 / PubMed / Full text
Visit-to-Visit Blood Pressure Variability and Mortality and Cardiovascular Outcomes Among Older Adults: The Health, Aging, and Body Composition Study. / 02.2017 / PubMed / Full text
Omega-3 polyunsaturated fatty acid supplementation attenuates blood pressure increase at onset of isometric handgrip exercise in healthy young and older humans. / 07.2016 / PubMed / Full text
Acute resistance exercise with blood flow restriction in elderly hypertensive women: haemodynamic, rating of perceived exertion and blood lactate. / 01.2018 / PubMed / Full text
Observational and mechanistic links between C-reactive protein and blood pressure in elderly women. / 07.2016 / PubMed / Full text
Dehydroepiandrosterone-sulfate is associated with cardiovascular reactivity to stress in women. / 07.2016 / PubMed / Full text
Quantifying sympathetic neuro-haemodynamic transduction at rest in humans: insights into sex, ageing and blood pressure control. / 01.09.2016 / PubMed / Full text
Age-Related Changes of Intraocular Pressure in Elderly People in Southern China: Lingtou Eye Cohort Study. / 2016 / PubMed / Full text
Cross-sectional relations of race and poverty status to cardiovascular risk factors in the Healthy Aging in Neighborhoods of Diversity across the Lifespan (HANDLS) study. / 14.03.2016 / PubMed / Full text
In utero-exposed di(n-butyl) phthalate induce dose dependent, age-related changes of morphology and testosterone-biosynthesis enzymes/associated proteins of Leydig cell mitochondria in rats. / 04.2016 / PubMed / Full text
The association between SBP and mortality risk differs with level of cognitive function in very old individuals. / 04.2016 / PubMed / Full text
Single Agent Antihypertensive Therapy and Orthostatic Blood Pressure Behaviour in Older Adults Using Beat-to-Beat Measurements: The Irish Longitudinal Study on Ageing. / 2016 / PubMed / Full text
Sleeve Gastrectomy Decreases Body Weight, Whole-Body Adiposity, and Blood Pressure Even in Aged Diet-Induced Obese Rats. / 07.2016 / PubMed / Full text
Determinants of pulse pressure and annual rates of change in the Atherosclerosis Risk in Communities study. / 12.2015 / PubMed / Full text
Age- and Functional Status-Dependent Association Between Blood Pressure and Cognition: The Milan Geriatrics 75 Cohort Study. / 09.2015 / PubMed / Full text
The correlation between blood pressure and kidney function decline in older people: a registry-based cohort study. / 30.06.2015 / PubMed / Full text
Avoidance of polypharmacy and excessive blood pressure control is associated with improved renal function in older patients. / 07.2015 / PubMed / Full text
Relationship Between 24-Hour Ambulatory Blood Pressure and Cognitive Function in Community-Living Older Adults: The UCSD Ambulatory Blood Pressure Study. / 12.2015 / PubMed / Full text
Longitudinal changes in cortical thinning associated with hypertension. / 06.2015 / PubMed / Full text
Mildly elevated blood pressure is a marker for better health status in Polish centenarians. / 02.2015 / PubMed / Full text
Decreased peripheral arterial volume distensibility in patients with branch retinal vein occlusion in comparison with normal subjects. / 20.10.2014 / PubMed / Full text
Is there a differential impact of parity on blood pressure by age? / 11.2014 / PubMed / Full text
Effects of cardiorespiratory fitness on blood pressure trajectory with aging in a cohort of healthy men. / 23.09.2014 / PubMed / Full text
Orthostatic hypotension is associated with more severe hypertension in elderly autonomous diabetic patients from the French Gerodiab study at inclusion. / 06.2014 / PubMed / Full text
Joint effect of mid- and late-life blood pressure on the brain: the AGES-Reykjavik study. / 17.06.2014 / PubMed / Full text
The correlation between peripheral leukocyte telomere length and indicators of cardiovascular aging. / 09.2014 / PubMed / Full text
Different acute cardiovascular stress in response to resistance exercise leading to failure versus not to failure in elderly women with and without hypertension--a pilot study. / 03.2015 / PubMed / Full text
Diastolic blood pressure, aortic atheroma, and prognosis in hypertension: new insights into a complex association. / 03.2014 / PubMed / Full text
Leukoaraiosis and ambulatory blood pressure load in a healthy elderly cohort study: the PROOF study. / 01.03.2014 / PubMed / Full text
The age-related hemodynamic changes of blood pressure and their impact on the incidence of cardiovascular disease and stroke: new evidence. / 02.2014 / PubMed / Full text
Orthostatic hypotension is associated with lower cognitive performance in adults aged 50 plus with supine hypertension. / 07.2014 / PubMed / Full text
Growth-related disappearance of the childhood relationship between height and blood pressure levels. / 01-02.2014 / PubMed / Full text
Blood pressure changes associated with periodic leg movements during sleep in healthy subjects. / 06.2013 / PubMed / Full text
A randomized 9-month study of blood pressure and body fat responses to aerobic training versus combined aerobic and resistance training in older men. / 08.2013 / PubMed / Full text
Association between blood pressure and DNA methylation of retrotransposons and pro-inflammatory genes. / 02.2013 / PubMed / Full text
[Age and arterial hypertension in hemodialysis patients]. / 07.2012 / PubMed
Aging attenuates the interarm diastolic blood pressure difference induced by one-arm exercise. / 04.2013 / PubMed / Full text
Blood pressure in relation to age and frailty. / 03.2011 / PubMed / Full text

H2AX[править]

REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. / 17.11.2020 / PubMed / Full text
A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma. / 13.10.2020 / PubMed / Full text
Exposing human primary dermal fibroblasts to particulate matter induces changes associated with skin aging. / 11.2020 / PubMed / Full text
Evaluation of GammaH2AX in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer's Disease in the AIBL Study of Ageing. / 06.08.2020 / PubMed / Full text
Doxorubicin generates senescent microglia that exhibit altered proteomes, higher levels of cytokine secretion, and a decreased ability to internalize amyloid β. / 15.10.2020 / PubMed / Full text
Cisplatin-induced peripheral neuropathy is associated to neuronal senescence-like response. / 29.06.2020 / PubMed / Full text
Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition. / 07.2020 / PubMed / Full text
Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling. / 01.05.2020 / PubMed / Full text
Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites. / 06.04.2020 / PubMed / Full text
The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage. / 03.12.2019 / PubMed / Full text
Do BRCA1 and BRCA2 gene mutation carriers have a reduced ovarian reserve? Protocol for a prospective observational study. / 25.11.2019 / PubMed / Full text
Slower rates of accumulation of DNA damage in leukocytes correlate with longer lifespans across several species of birds and mammals. / 15.11.2019 / PubMed / Full text
Phosphoproteomic analysis reveals plant DNA damage signalling pathways with a functional role for histone H2AX phosphorylation in plant growth under genotoxic stress. / 12.2019 / PubMed / Full text
Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress. / 10.2019 / PubMed / Full text
Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging? / 2019 / PubMed / Full text
Epigallocatechin-3-gallate induces telomere shortening and clastogenic damage in glioblastoma cells. / 10.2019 / PubMed / Full text
Expression of RNF8 on cochlear apoptosis and aging in mice of different ages. / 03-Apr,.2019 / PubMed
Mitochondrial Protection Partly Mitigates Kidney Cellular Senescence in Swine Atherosclerotic Renal Artery Stenosis. / 2019 / PubMed / Full text
Old age increases microglial senescence, exacerbates secondary neuroinflammation, and worsens neurological outcomes after acute traumatic brain injury in mice. / 05.2019 / PubMed / Full text
Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth. / 01.05.2019 / PubMed / Full text
PFG acted as an inducer of premature senescence in TIG-1 normal diploid fibroblast and an inhibitor of mitosis in the HeLa cells. / 06.2019 / PubMed / Full text
S100A13 promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α. / 23.01.2019 / PubMed / Full text
Clostridium difficile toxin B induces senescence in enteric glial cells: A potential new mechanism of Clostridium difficile pathogenesis. / 12.2018 / PubMed / Full text
Varenicline reduces DNA damage, tau mislocalization and post surgical cognitive impairment in aged mice. / 12.2018 / PubMed / Full text
The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. / 2018 / PubMed / Full text
Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. / 10.2018 / PubMed / Full text
Acetylation of PGC1α by Histone Deacetylase 1 Downregulation Is Implicated in Radiation-Induced Senescence of Brain Endothelial Cells. / 16.05.2019 / PubMed / Full text
Role of accelerated aging in limb muscle wasting of patients with COPD. / 2018 / PubMed / Full text
[Protective effect of Wuzi Yanzong recipe on testicular DNA damage and apoptosis in natural ageing rats]. / 04.2018 / PubMed / Full text
Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions. / 04.01.2018 / PubMed / Full text
Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice. / 15.11.2017 / PubMed / Full text
Therapeutic doses of doxorubicin induce premature senescence of human mesenchymal stem cells derived from menstrual blood, bone marrow and adipose tissue. / 03.2018 / PubMed / Full text
Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice. / 07.10.2017 / PubMed / Full text
The Cytolethal Distending Toxin Subunit CdtB of [i]Helicobacter hepaticus[/i] Promotes Senescence and Endoreplication in Xenograft Mouse Models of Hepatic and Intestinal Cell Lines. / 2017 / PubMed / Full text
Increased level of DNA damage in some organs of obese Zucker rats by γ-H2AX analysis. / 08.2017 / PubMed / Full text
[The Role of DNA Double-strain Damage Repairing Mechanisms in Diabetic Atheroscolersis]. / 03.2017 / PubMed
DNA damage marker phosphorylated histone H2AX is a potential predictive marker for progression of epithelial dysplasia of the oral cavity. / 10.2017 / PubMed / Full text
Tumor stroma with senescence-associated secretory phenotype in steatohepatitic hepatocellular carcinoma. / 2017 / PubMed / Full text
Metformin alleviates ageing cellular phenotypes in Hutchinson-Gilford progeria syndrome dermal fibroblasts. / 10.2017 / PubMed / Full text
Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes. / 12.2017 / PubMed / Full text
Liver damage and senescence increases in patients developing hepatocellular carcinoma. / 08.2017 / PubMed / Full text
The Chromatin-Associated Phf12 Protein Maintains Nucleolar Integrity and Prevents Premature Cellular Senescence. / 01.03.2017 / PubMed / Full text
Axitinib induces senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner. / 10.01.2017 / PubMed / Full text
Detection of Dysfunctional Telomeres in Oncogene-Induced Senescence. / 2017 / PubMed / Full text
Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice. / 07.10.2016 / PubMed / Full text
Overexpression of catalase in mice reduces age-related oxidative stress and maintains sperm production. / 11.2016 / PubMed / Full text
BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries. / 03.04.2017 / PubMed / Full text
In vitro model for DNA double-strand break repair analysis in breast cancer reveals cell type-specific associations with age and prognosis. / 11.2016 / PubMed / Full text
Effects of Aging and Oxidative Stress on Spermatozoa of Superoxide-Dismutase 1- and Catalase-Null Mice. / 09.2016 / PubMed / Full text
Growth arrest of lung carcinoma cells (A549) by polyacrylate-anchored peroxovanadate by activating Rac1-NADPH oxidase signalling axis. / 09.2016 / PubMed / Full text
p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish. / 26.07.2016 / PubMed / Full text
Mesenchymal stromal cells having inactivated RB1 survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy. / 02.2017 / PubMed / Full text
The impact of autophagy on cell death modalities in CRL-5876 lung adenocarcinoma cells after their exposure to γ-rays and/or erlotinib. / 04.2016 / PubMed / Full text
Dehydroleucodine inhibits tumor growth in a preclinical melanoma model by inducing cell cycle arrest, senescence and apoptosis. / 01.03.2016 / PubMed / Full text
SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin. / 03.2016 / PubMed / Full text
Persistent γH2AX: A promising molecular marker of DNA damage and aging. / 10-12.2015 / PubMed / Full text
Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells. / 03.11.2015 / PubMed / Full text
Comparative proteomic analysis of primordial follicles from ovaries of immature and aged rats. / 2015 / PubMed / Full text
Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities. / 18.08.2015 / PubMed / Full text
Impairing the radioresistance of cancer cells by hydrogenated nanodiamonds. / 08.2015 / PubMed / Full text
Long-term arsenite exposure induces premature senescence in B cell lymphoma A20 cells. / 04.2016 / PubMed / Full text
Changes in the expression of DNA double strand break repair genes in primordial follicles from immature and aged rats. / 03.2015 / PubMed / Full text
Long-term Neuroglial Cocultures as a Brain Aging Model: Hallmarks of Senescence, MicroRNA Expression Profiles, and Comparison With In Vivo Models. / 01.2016 / PubMed / Full text
Loss of Nfkb1 leads to early onset aging. / 11.2014 / PubMed / Full text
Oxidative Glial Cell Damage Associated with White Matter Lesions in the Aging Human Brain. / 09.2015 / PubMed / Full text
Gallotannin is a DNA damaging compound that induces senescence independently of p53 and p21 in human colon cancer cells. / 10.2015 / PubMed / Full text
Oxidative DNA damage causes premature senescence in mouse embryonic fibroblasts deficient for Krüppel-like factor 4. / 09.2015 / PubMed / Full text
HP1α mediates defective heterochromatin repair and accelerates senescence in Zmpste24-deficient cells. / 2014 / PubMed / Full text
Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication. / 2014 / PubMed / Full text
[Correlation between DNA damage and EB virus infection in nasopharyngeal carcinoma]. / 02.2014 / PubMed
Phosphorylation of histone H2AX in the mouse brain from development to senescence. / 21.01.2014 / PubMed / Full text
Mapping NAD( ) metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence. / 04.2014 / PubMed / Full text
Rac1 modulates acute and subacute genotoxin-induced hepatic stress responses, fibrosis and liver aging. / 21.03.2013 / PubMed / Full text
Primary human muscle precursor cells obtained from young and old donors produce similar proliferative, differentiation and senescent profiles in culture. / 06.2013 / PubMed / Full text

NLRP3[править]

Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience. / 12.2020 / PubMed / Full text
Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism. / 06.11.2020 / PubMed / Full text
Panax notoginseng saponins attenuate neuroinflammation through TXNIP-mediated NLRP3 inflammasome activation in aging rats. / 10.11.2020 / PubMed / Full text
TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity. / 27.10.2020 / PubMed / Full text
Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and NLRP3 inflammasome. / 01.01.2021 / PubMed / Full text
A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma. / 13.10.2020 / PubMed / Full text
Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress. / 2020 / PubMed / Full text
Mechanisms of NLRP3 priming in inflammaging and age related diseases. / 10.2020 / PubMed / Full text
Lamivudine Inhibits [i]Alu[/i] RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities. / 07.2020 / PubMed / Full text
The NLRP3 Inflammasome: Metabolic Regulation and Contribution to Inflammaging. / 30.07.2020 / PubMed / Full text
Aging aggravated liver ischemia and reperfusion injury by promoting STING-mediated NLRP3 activation in macrophages. / 08.2020 / PubMed / Full text
Targeting NLRP3 Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss. / 10.2020 / PubMed / Full text
Fatty food, fatty acids, and microglial priming in the adult and aged hippocampus and amygdala. / 10.2020 / PubMed / Full text
Korean Red Ginseng Suppresses the Expression of Oxidative Stress Response and NLRP3 Inflammasome Genes in Aged C57BL/6 Mouse Ovaries. / 22.04.2020 / PubMed / Full text
Cepharanthine promotes the effect of dexmedetomidine on the deposition of β-amyloid in the old age of the senile dementia rat model by regulating inflammasome expression. / 2019 / PubMed / Full text
Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice. / 08.04.2020 / PubMed / Full text
Ginsenoside Rg1 ameliorates glomerular fibrosis during kidney aging by inhibiting NOX4 and NLRP3 inflammasome activation in SAMP8 mice. / 27.02.2020 / PubMed / Full text
Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice. / 04.2020 / PubMed / Full text
Autophagy and NLRP3 inflammasome crosstalk in neuroinflammation in aged bovine brains. / 06.2020 / PubMed / Full text
Cellular senescence induced by S100A9 in mesenchymal stromal cells through NLRP3 inflammasome activation. / 14.11.2019 / PubMed / Full text
NLRP3 Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity. / 13.07.2020 / PubMed / Full text
NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice. / 01.2020 / PubMed / Full text
Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging. / 08.09.2019 / PubMed / Full text
Effect of Aging on Taurine Transporter (TauT) Expression in the Mouse Brain Cortex. / 2019 / PubMed / Full text
Tamoxifen-induced, intestinal-specific deletion of [i]Slc5a6[/i] in adult mice leads to spontaneous inflammation: involvement of NF-κB, NLRP3, and gut microbiota. / 01.10.2019 / PubMed / Full text
Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome. / 02.09.2019 / PubMed / Full text
Aging in the Syrian hamster testis: Inflammatory-oxidative status and the impact of photoperiod. / 09.2019 / PubMed / Full text
[Improved effects of saponins from Panax japonicus on decline of cognitive function in natural aging rats via NLRP3 inflammasome pathway]. / 01.2019 / PubMed / Full text
Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin. / 04.10.2019 / PubMed / Full text
Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks. / 11.03.2019 / PubMed / Full text
NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats. / 04.2019 / PubMed / Full text
Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. / 22.01.2019 / PubMed / Full text
Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence. / 05.2019 / PubMed / Full text
Inhibiting the NLRP3 Inflammasome With MCC950 Ameliorates Isoflurane-Induced Pyroptosis and Cognitive Impairment in Aged Mice. / 2018 / PubMed / Full text
Klotho controls the brain-immune system interface in the choroid plexus. / 27.11.2018 / PubMed / Full text
NLRP3 inflammasome activation in inflammaging. / 12.2018 / PubMed / Full text
Melatonin and inflammation-Story of a double-edged blade. / 11.2018 / PubMed / Full text
A response to readers' comments. / 14.09.2018 / PubMed / Full text
NLRP3 inflammasome-dependent pyroptosis is proposed to be involved in the mechanism of age-dependent isoflurane-induced cognitive impairment. / 14.09.2018 / PubMed / Full text
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. / 09.2018 / PubMed / Full text
Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain. / 06.2018 / PubMed / Full text
Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment. / 17.04.2018 / PubMed / Full text
Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection. / 05.2018 / PubMed / Full text
AMP-Activated Protein Kinase Regulation of the NLRP3 Inflammasome during Aging. / 01.2018 / PubMed / Full text
Effects of chronically increased VEGF-A on the aging heart. / 03.2018 / PubMed / Full text
NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection. / 01.03.2018 / PubMed / Full text
Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. / 05.10.2017 / PubMed / Full text
Specific calpain inhibition protects kidney against inflammaging. / 14.08.2017 / PubMed / Full text
Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress. / 28.06.2017 / PubMed / Full text
The NLRP3 inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice. / 01.08.2017 / PubMed / Full text
Human Plasma Thioredoxin-80 Increases With Age and in ApoE Mice Induces Inflammation, Angiogenesis, and Atherosclerosis. / 01.08.2017 / PubMed / Full text
Metaflammation: Tissue-Specific Alterations of the NLRP3 Inflammasome Platform in Metabolic Syndrome. / 2018 / PubMed / Full text
Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of Apc mice. / 11.04.2017 / PubMed / Full text
β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares. / 28.02.2017 / PubMed / Full text
Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein (TXNIP) pathway. / 03.2017 / PubMed / Full text
Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. / 02.2017 / PubMed / Full text
Aging-Associated TNF Production Primes Inflammasome Activation and NLRP3-Related Metabolic Disturbances. / 01.10.2016 / PubMed / Full text
Hepatic NAD( ) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing. / 08.2016 / PubMed / Full text
Age-Dependent Susceptibility to Pulmonary Fibrosis Is Associated with NLRP3 Inflammasome Activation. / 08.2016 / PubMed / Full text
Increased VEGF-A promotes multiple distinct aging diseases of the eye through shared pathomechanisms. / 01.03.2016 / PubMed / Full text
Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence. / 23.02.2016 / PubMed / Full text
Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. / 03.2016 / PubMed / Full text
Nod-like receptor pyrin containing 3 (NLRP3) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation. / 01.2016 / PubMed / Full text
Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age. / 2015 / PubMed / Full text
A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice. / 2015 / PubMed / Full text
Purple sweet potato color inhibits endothelial premature senescence by blocking the NLRP3 inflammasome. / 10.2015 / PubMed / Full text
Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye. / 24.06.2015 / PubMed / Full text
A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in mice. / 06.2015 / PubMed / Full text
Drivers of age-related inflammation and strategies for healthspan extension. / 05.2015 / PubMed / Full text
DAMPs as mediators of sterile inflammation in aging-related pathologies. / 11.2015 / PubMed / Full text
Protective effect of telmisartan on neurovascular unit and inflammasome in stroke-resistant spontaneously hypertensive rats. / 06.2015 / PubMed / Full text
P2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the NLRP3/ASC/caspase 1 pathway. / 12.2013 / PubMed / Full text
Deep tissue injury in development of pressure ulcers: a decrease of inflammasome activation and changes in human skin morphology in response to aging and mechanical load. / 2013 / PubMed / Full text
Differential pathways for interleukin-1β production activated by chromogranin A and amyloid β in microglia. / 12.2013 / PubMed / Full text

F2[править]

A Comprehensive Analysis of Age and Gender Effects in European Portuguese Oral Vowels. / 05.12.2020 / PubMed / Full text
Environmental risk assessment of glufosinate-resistant soybean by pollen-mediated gene flow under field conditions in the region of the genetic origin. / 17.10.2020 / PubMed / Full text
Prenatal exposure to an environmentally relevant phthalate mixture accelerates biomarkers of reproductive aging in a multiple and transgenerational manner in female mice. / 28.10.2020 / PubMed / Full text
Gestational arsenite exposure augments hepatic tumors of C3H mice by promoting senescence in F1 and F2 offspring via different pathways. / 01.12.2020 / PubMed / Full text
Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone. / 01.07.2020 / PubMed / Full text
Conclusions from a behavioral aging study on male and female F2 hybrid mice on age-related behavior, buoyancy in water-based tests, and an ethical method to assess lifespan. / 11.09.2019 / PubMed / Full text
In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. / 2019 / PubMed / Full text
Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice. / 09.2019 / PubMed / Full text
Effect of zirconia surface treatment, resin cement and aging on the load-bearing capacity under fatigue of thin simplified full-contour Y-TZP restorations. / 09.2019 / PubMed / Full text
Maternal Resveratrol Supplementation Prevents Cognitive Decline in Senescent Mice Offspring. / 06.03.2019 / PubMed / Full text
Transgenerational hormetic effects of sublethal dose of flupyradifurone on the green peach aphid, Myzus persicae (Sulzer) (Hemiptera: Aphididae). / 2019 / PubMed / Full text
Early treatment of acute hepatitis C infection is cost-effective in HIV-infected men-who-have-sex-with-men. / 2019 / PubMed / Full text
Adult rat morphine exposure changes morphine preference, anxiety, and the brain expression of dopamine receptors in male offspring. / 10.2018 / PubMed / Full text
Age-related changes in shock absorption capacity of the human spinal column. / 2018 / PubMed / Full text
Influence of Supplemental Protein on the Life Expectancy and Reproduction of the Chinese Citrus Fruit Fly, Bactrocera minax (Enderlein) (Tetradacus minax) (Diptera: Tephritidae). / 01.03.2018 / PubMed / Full text
Effect of Cold Storage on Biological Traits of Psix saccharicola (Hymenoptera: Platygastridae), an Egg Parasitoid of Acrosternum arabicum (Hemiptera: Pentatomidae). / 28.05.2018 / PubMed / Full text
Short-Term Genetic Selection for Adolescent Locomotor Sensitivity to Delta9-Tetrahydrocannabinol (THC). / 05.2018 / PubMed / Full text
Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice. / 14.03.2018 / PubMed / Full text
F2-Isoprostanes Reflect Oxidative Stress Correlated With Lean Mass and Bone Density but Not Insulin Resistance. / 01.05.2017 / PubMed / Full text
Multigenerational effects of 4-methylbenzylidene camphor (4-MBC) on the survival, development and reproduction of the marine copepod Tigriopus japonicus. / 01.2018 / PubMed / Full text
Effects of Aging on Vocal Fundamental Frequency and Vowel Formants in Men and Women. / 09.2018 / PubMed / Full text
Is Longevity a Heritable Trait? Evidence for Non-genomic Influence from an Extended Longevity Phenotype of Drosophila melanogaster. / 2018 / PubMed / Full text
Effects of cold storage on the biological characteristics of Microplitis prodeniae (Hymenoptera: Braconidae). / 08.2017 / PubMed / Full text
Chronic exposure of zinc oxide nanoparticles causes deviant phenotype in Drosophila melanogaster. / 05.04.2017 / PubMed / Full text
The Interaction of Lexical Characteristics and Speech Production in Parkinson's Disease. / 01.01.2017 / PubMed / Full text
Polyunsaturated fatty acids ameliorate aging via redox-telomere-antioncogene axis. / 31.01.2017 / PubMed / Full text
Stage dependent nutritional regulation of transgenerational longevity. / 27.10.2016 / PubMed / Full text
Transgenerational programming of longevity through E(z)-mediated histone H3K27 trimethylation in [i]Drosophila[/i]. / 25.11.2016 / PubMed / Full text
Correlation between flexural and indirect tensile strength of resin composite cements. / 04.11.2016 / PubMed / Full text
Effects of aging and freezing/thawing sequence on quality attributes of bovine [i]Mm. gluteus medius[/i] and [i]biceps femoris[/i]. / 02.2017 / PubMed / Full text
Active Cigarette Smoking in Cognitively-Normal Elders and Probable Alzheimer's Disease is Associated with Elevated Cerebrospinal Fluid Oxidative Stress Biomarkers. / 25.07.2016 / PubMed / Full text
Treatment of Chronic Hepatitis C in the Aged - Does It Impact Life Expectancy? A Decision Analysis. / 2016 / PubMed / Full text
The long-term effects of acute exposure to ionising radiation on survival and fertility in Daphnia magna. / 10.2016 / PubMed / Full text
Elevated plasma F2-isoprostane levels in schizophrenia. / 10.2016 / PubMed / Full text
Effects of Usag-1 and Bmp7 deficiencies on murine tooth morphogenesis. / 13.05.2016 / PubMed / Full text
Transgenerational effects of maternal diet on metabolic and reproductive ageing. / 08.2016 / PubMed / Full text
Transgenerational programming of longevity and reproduction by post-eclosion dietary manipulation in Drosophila. / 05.2016 / PubMed / Full text
Mutated Huntingtin Causes Testicular Pathology in Transgenic Minipig Boars. / 2016 / PubMed / Full text
Spectrographic Acoustic Vocal Characteristics of Elderly Women Engaged in Aerobics. / 09.2016 / PubMed / Full text
The Effect of Different Host Plants on Development and Survival of Nysius natalensis (Hemiptera: Orsillidae). / 02.2015 / PubMed / Full text
Effect of semolina-jaggery diet on survival and development of Drosophila melanogaster. / 2015 / PubMed / Full text
Ovarian senescence increases liver fibrosis in humans and zebrafish with steatosis. / 09.2015 / PubMed / Full text
A Chromosome 13 locus is associated with male-specific mortality in mice. / 02.2016 / PubMed / Full text
A systematic approach to standardize artificial aging of resin composite cements. / 07.2015 / PubMed / Full text
Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype. / 08.2015 / PubMed / Full text
Pregnant growth restricted female rats have bone gains during late gestation which contributes to second generation adolescent and adult offspring having normal bone health. / 05.2015 / PubMed / Full text
Vitamin C deficiency in the brain impairs cognition, increases amyloid accumulation and deposition, and oxidative stress in APP/PSEN1 and normally aging mice. / 15.04.2015 / PubMed / Full text
The significance of body mass index in calculating the cut-off points for low muscle mass in the elderly: methodological issues. / 2014 / PubMed / Full text
Acute exercise increases resistance to oxidative stress in young but not older adults. / 2014 / PubMed / Full text
Transgenerational left ventricular hypertrophy and hypertension in offspring after uteroplacental insufficiency in male rats. / 11.2014 / PubMed / Full text
Genetic Regulation of Female Sexual Maturation and Longevity Through Circulating IGF1. / 07.2015 / PubMed / Full text
Influence of lifestyle modifications on age-related free radical injury to brain. / 09.2014 / PubMed / Full text
Influence of endothelial dysfunction on telomere length in subjects with metabolic syndrome: LIPGENE study. / 2014 / PubMed / Full text
Fine mapping of the lesion mimic and early senescence 1 (lmes1) in rice (Oryza sativa). / 07.2014 / PubMed / Full text
In utero undernutrition in male mice programs liver lipid metabolism in the second-generation offspring involving altered Lxra DNA methylation. / 03.06.2014 / PubMed / Full text
Cross-sectional and longitudinal relationships between cerebrospinal fluid biomarkers and cognitive function in people without cognitive impairment from across the adult life span. / 06.2014 / PubMed / Full text
Effects of radiation on inherited sterility in the European grapevine moth (Lobesia botrana). / 01.2015 / PubMed / Full text
F2-isoprostanes as a biomarker of oxidative stress in the mouse bladder. / 05.2014 / PubMed / Full text
[Clinical and genetic characteristics of long-livers in Moscow region]. / 2013 / PubMed
The use of a heterogeneously controlled mouse population reveals a significant correlation of acute phase parasitemia with mortality in Chagas disease. / 2014 / PubMed / Full text
Genes belonging to the insulin and ecdysone signaling pathways can contribute to developmental time, lifespan and abdominal size variation in Drosophila americana. / 2014 / PubMed / Full text
Protein thiol oxidation does not change in skeletal muscles of aging female mice. / 02.2014 / PubMed / Full text
Perennially young: seed production and quality in controlled and natural populations of Cistus albidus reveal compensatory mechanisms that prevent senescence in terms of seed yield and viability. / 01.2014 / PubMed / Full text
QTLs influencing IGF-1 levels in a LOU/CxFischer 344F2 rat population. Tracks towards the metabolic theory of Ageing. / 12.2013 / PubMed / Full text
Effects of body-color mutations on vitality: an attempt to establish easy-to-breed see-through medaka strains by outcrossing. / 04.09.2013 / PubMed / Full text
Inducible transgenic expression in the short-lived fish Nothobranchius furzeri. / 05.2013 / PubMed / Full text
Reproductive and genotoxic effects in zebrafish after chronic exposure to methyl methanesulfonate in a multigeneration study. / 07.2013 / PubMed / Full text
Drosophila americana as a model species for comparative studies on the molecular basis of phenotypic variation. / 2013 / PubMed / Full text
Comparative analysis of quantitative trait loci for body weight, growth rate and growth curve parameters from 3 to 72 weeks of age in female chickens of a broiler-layer cross. / 13.03.2013 / PubMed / Full text
Age-dependent responsiveness of human female bone cells to vitamin D analog and PTH. / 02.2013 / PubMed / Full text
Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice. / 07.2013 / PubMed / Full text
The effect of grand maternal nicotine exposure during gestation and lactation on lung integrity of the F2 generation. / 01.2014 / PubMed / Full text
Influence of Orientia tsutsugamushi infection on the developmental biology of Leptotrombidium imphalum and Leptotrombidium chiangraiensis (Acari: Trombiculidae). / 11.2012 / PubMed / Full text

CAD[править]

Serum soluble Klotho is inversely related to coronary artery calcification assessed by intravascular ultrasound in patients with stable coronary artery disease. / 07.12.2020 / PubMed / Full text
Shear bond strengths of aged and non-aged CAD/CAM materials after different surface treatments. / 10.2020 / PubMed / Full text
Prediction of Early Postoperative Major Cardiac Events and In-Hospital Mortality in Elderly Hip Fracture Patients: The Role of Different Types of Preoperative Cardiac Abnormalities on Echocardiography Report. / 2020 / PubMed / Full text
Pathogenesis of chronic heart failure: cardiovascular aging, risk factors, comorbidities, and disease modifiers. / 10.06.2020 / PubMed / Full text
Impact of age on clinical outcomes of antihypertensive therapy in patients with hypertension and coronary artery disease: A sub-analysis of the Heart Institute of Japan Candesartan Randomized Trial for Evaluation in Coronary Artery Disease. / 06.2020 / PubMed / Full text
Impact of the early-life skin microbiota on the development of canine atopic dermatitis in a high-risk breed birth cohort. / 23.01.2020 / PubMed / Full text
[Polymorbidity in elderly patients needing myocardial revascularization (a review article).] / 2019 / PubMed
Fracture force of CAD/CAM resin composite crowns after in vitro aging. / 07.2020 / PubMed / Full text
Clinical performance of chairside monolithic lithium disilicate glass-ceramic CAD-CAM crowns. / 11.2019 / PubMed / Full text
Acute resveratrol supplementation in coronary artery disease: towards patient stratification. / 02.2020 / PubMed / Full text
Cellular response to moderate chromatin architectural defects promotes longevity. / 07.2019 / PubMed / Full text
Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway. / 10.06.2019 / PubMed / Full text
Altering of optical and mechanical properties in high-translucent CAD-CAM resin composites during aging. / 06.2019 / PubMed / Full text
Age-Related Improvements in Peak Cardiorespiratory Fitness among Coronary Heart Disease Patients Following Cardiac Rehabilitation. / 05.03.2019 / PubMed / Full text
Revisiting Intermittent Therapy in Metastatic Prostate Cancer: Can Less Be More in the "New World Order"? / 03.2019 / PubMed / Full text
Effect of UV aging on translucency of currently used esthetic CAD-CAM materials. / 03.2019 / PubMed / Full text
An economic analysis of salmonella detection in fresh produce, poultry, and eggs using whole genome sequencing technology in Canada. / 02.2019 / PubMed / Full text
Age, Sex, and Cardiovascular Risk Attributable to Lipoprotein Cholesterol Among Chinese Individuals with Coronary Artery Disease: A Case-Control Study. / 05.2019 / PubMed / Full text
Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease. / 05.2019 / PubMed / Full text
Age-dependent association of pulse wave velocity with coronary artery disease and myocardial aging in high-risk patients. / 04.2019 / PubMed / Full text
The Effect of Residential Aged Care Size, Ownership Model, and Multichain Affiliation on Resident Comfort and Symptom Management at the End of Life. / 03.2019 / PubMed / Full text
Cardiovascular disease in nonagenarians: Prevalence and utilization of preventive therapies. / 03.2019 / PubMed / Full text
Potential associations of testosterone/estradiol ratio, leukocyte hTERT expression and PBMC telomerase activity with aging and the presence of coronary artery disease in men. / 03.2019 / PubMed / Full text
Assessment of cardiovascular risk and preparticipation screening protocols in masters athletes: the Masters Athlete Screening Study (MASS): a cross-sectional study. / 2018 / PubMed / Full text
Comparison of marginal fit between CAD-CAM and hot-press lithium disilicate crowns. / 01.2019 / PubMed / Full text
Prognostic value of age adjusted segment involvement score as measured by coronary computed tomography: a potential marker of vascular age. / 11.2018 / PubMed / Full text
Vitamin D levels correlate with lymphocyte subsets in elderly patients with age-related diseases. / 16.05.2018 / PubMed / Full text
Effect of metabolic syndrome and aging on Ca dysfunction in coronary smooth muscle and coronary artery disease severity in Ossabaw miniature swine. / 15.07.2018 / PubMed / Full text
Definitions and clinical impact of revascularization completeness. / 10.2018 / PubMed / Full text
MicroRNA-216a induces endothelial senescence and inflammation via Smad3/IκBα pathway. / 05.2018 / PubMed / Full text
Heart Rate Fragmentation: A Symbolic Dynamical Approach. / 2017 / PubMed / Full text
Diabetes Care Disparities in Long-standing Type 1 Diabetes in Canada and the U.S.: A Cross-sectional Comparison. / 01.2018 / PubMed / Full text
The effects of aerobic and anaerobic exercises on circulating soluble-Klotho and IGF-I in young and elderly adults and in CAD patients. / 01-12.2017 / PubMed / Full text
Association between coronary artery disease severity and overactive bladder in geriatric patients. / 01.2018 / PubMed / Full text
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. / 13.10.2017 / PubMed / Full text
Association Between Mental Health Burden and Coronary Artery Disease in U.S. Women Veterans Over 45: A National Cross-Sectional Study. / 03.2018 / PubMed / Full text
Internal carotid artery dissection among younger and older patients with acute ischemic stroke. / 04.2018 / PubMed / Full text
In Vitro versus In Vivo Phase Instability of Zirconia-Toughened Alumina Femoral Heads: A Critical Comparative Assessment. / 28.04.2017 / PubMed / Full text
Conflicting relationship between age-dependent disorders, valvular heart disease and coronary artery disease by covariance structure analysis: Possible contribution of natriuretic peptide. / 2017 / PubMed / Full text
Age-related modulation of angiogenesis-regulating factors in the swine meniscus. / 11.2017 / PubMed / Full text
Central adiposity and the overweight risk paradox in aging: follow-up of 130,473 UK Biobank participants. / 07.2017 / PubMed / Full text
Heart Rate Fragmentation: A New Approach to the Analysis of Cardiac Interbeat Interval Dynamics. / 2017 / PubMed / Full text
[Studying of the factors influencing biological age of long-livers of Almaty]. / 2017 / PubMed
Management and risk factor control of coronary artery disease in elderly versus nonelderly: a multicenter registry. / 12.2016 / PubMed / Full text
Identification of the main determinants of abdominal aorta size: a screening by Pocket Size Imaging Device. / 13.01.2017 / PubMed / Full text
Transition in the mechanism of flow-mediated dilation with aging and development of coronary artery disease. / 01.2017 / PubMed / Full text
Longevity-Associated FOXO3 Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations. / 01.05.2017 / PubMed / Full text
Effects of aging and coronary artery disease on sympathetic neural recruitment strategies during end-inspiratory and end-expiratory apnea. / 01.10.2016 / PubMed / Full text
Impact of Age on the Functional Significance of Intermediate Epicardial Artery Disease. / 24.06.2016 / PubMed / Full text
N-carboxymethyllysine as a biomarker for coronary artery disease and age-related macular degeneration. / 2016 / PubMed / Full text
Selecting for neurogenic potential as an alternative for Alzheimer's disease drug discovery. / 06.2016 / PubMed / Full text
The Prognostic Value of Percentage Total Plaque Score Adjusted to Age. / 11.2016 / PubMed / Full text
WHO guidelines for a healthy diet and mortality from cardiovascular disease in European and American elderly: the CHANCES project. / 10.2015 / PubMed / Full text
Major adverse cardiac events in elderly patients with coronary artery disease undergoing noncardiac surgery: A multicenter prospective study in China. / 11-12.2015 / PubMed / Full text
Disease complexity in acute coronary syndrome is related to the patient's immunological status. / 2015 / PubMed / Full text
Telomere length and outcomes in ischaemic heart failure: data from the COntrolled ROsuvastatin multiNAtional Trial in Heart Failure (CORONA). / 03.2015 / PubMed / Full text
Low serum tryptophan predicts higher mortality in cardiovascular disease. / 03.2015 / PubMed / Full text
Impact of age on mean platelet volume and its relationship with coronary artery disease: a single-centre cohort study. / 02.2015 / PubMed / Full text
Benefits of exercise training and the correlation between aerobic capacity and functional outcomes and quality of life in elderly patients with coronary artery disease. / 10.2014 / PubMed / Full text
Association of traditional risk factors with coronary artery disease in nonagenarians: the primary role of hypertension. / 2014 / PubMed / Full text
Regulatory/effector T-cell ratio is reduced in coronary artery disease. / 2014 / PubMed / Full text
Acetylsalicylic acid, aging and coronary artery disease are associated with ABCA1 DNA methylation in men. / 2014 / PubMed / Full text
Comparison of arterial stiffness parameters in patients with coronary artery disease and diabetes mellitus using Arteriograph. / 2014 / PubMed / Full text
Chemerin levels as predictor of acute coronary events: a case-control study nested within the veterans affairs normative aging study. / 06.2014 / PubMed / Full text
Adipose-derived mesenchymal stromal cells from aged patients with coronary artery disease keep mesenchymal stromal cell properties but exhibit characteristics of aging and have impaired angiogenic potential. / 01.2014 / PubMed / Full text
Perfusion characteristics of Moyamoya disease: an anatomically and clinically oriented analysis and comparison. / 01.2014 / PubMed / Full text
Reduced Klotho is associated with the presence and severity of coronary artery disease. / 01.2014 / PubMed / Full text
The rs1333049 polymorphism on locus 9p21.3 and extreme longevity in Spanish and Japanese cohorts. / 04.2014 / PubMed / Full text
Age-related impact of depressive symptoms on functional capacity measured with 6-minute walking test in coronary artery disease. / 05.2014 / PubMed / Full text
Removable dental prostheses and cardiovascular survival: a 15-year follow-up study. / 08.2013 / PubMed / Full text
Endogenous sex steroid levels and cardiovascular disease in relation to the menopause: a systematic review. / 06.2013 / PubMed / Full text
Angiopoietin-like 2 promotes atherogenesis in mice. / 10.05.2013 / PubMed / Full text

C3[править]

Inverse association between periumbilical fat and longevity mediated by complement C3 and cardiac structure. / 18.11.2020 / PubMed / Full text
Complement C3 deficiency ameliorates aging related changes in the kidney. / 01.11.2020 / PubMed / Full text
Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration. / 2020 / PubMed / Full text
Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults. / 2020 / PubMed / Full text
Quantitative proteomics to study aging in rabbit liver. / 04.2020 / PubMed / Full text
Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice. / 04.2020 / PubMed / Full text
[Comparative analysis of experimental data about the effects of various polyphenols on lifespan and aging.] / 2019 / PubMed
Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization. / 01.09.2019 / PubMed / Full text
Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. / 06.2019 / PubMed / Full text
[Young and old animals use different strategies for forming an immune response to infectious agents (Pseudomonas aeruginosa и Escherichia coli).] / 2018 / PubMed
TREM2 triggers microglial density and age-related neuronal loss. / 03.2019 / PubMed / Full text
Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. / 2018 / PubMed / Full text
Traumatic Brain Injury in Aged Mice Induces Chronic Microglia Activation, Synapse Loss, and Complement-Dependent Memory Deficits. / 26.11.2018 / PubMed / Full text
Dialdehyde cellulose crosslinked poly(vinyl alcohol) hydrogels: Influence of catalyst and crosslinker shelf life. / 15.10.2018 / PubMed / Full text
Effects of Feeding Honey Bees (Hymenoptera: Apidae) With Industrial Sugars Produced by Plants Using Different Photosynthetic Cycles (Carbon C3 and C4) on the Colony Wintering Ability, Lifespan, and Forage Behavior. / 26.09.2018 / PubMed / Full text
The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. / 13.06.2018 / PubMed / Full text
Human Cord Blood Serum-Derived APP α-Secretase Cleavage Activity is Mediated by C1 Complement. / 04.2018 / PubMed / Full text
Altered gene expression pattern indicates the differential regulation of the immune response system as an important factor in cardiac aging. / 03.2019 / PubMed / Full text
Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix. / 2018 / PubMed / Full text
Aging-related tau astrogliopathy (ARTAG): not only tau phosphorylation in astrocytes. / 11.2018 / PubMed / Full text
A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity. / 04.2018 / PubMed / Full text
Computerized Cognitive Testing for Use in Clinical Trials: A Comparison of the NIH Toolbox and Cogstate C3 Batteries. / 2017 / PubMed / Full text
Antibodies to Senescent Antigen and C3 Are Not Required for Normal Red Blood Cell Lifespan in a Murine Model. / 2017 / PubMed / Full text
Gut dysbiosis breaks immunological tolerance toward the central nervous system during young adulthood. / 31.10.2017 / PubMed / Full text
Some immunological responses of common carp (Cyprinus carpio) fingerling to acute extremely low-frequency electromagnetic fields (50 Hz). / 02.2018 / PubMed / Full text
Metabolomics of laminae and midvein during leaf senescence and source-sink metabolite management in Brassica napus L. leaves. / 12.02.2018 / PubMed / Full text
d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. / 02.12.2017 / PubMed / Full text
Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model. / 2017 / PubMed / Full text
The changing shape of the ISCEV standard pattern onset VEP. / 08.2017 / PubMed / Full text
Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice. / 31.05.2017 / PubMed / Full text
Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text
Identification of a conserved gene signature associated with an exacerbated inflammatory environment in the hippocampus of aging rats. / 04.2017 / PubMed / Full text
Normative data for parameters of sagittal spinal alignment in healthy subjects: an analysis of gender specific differences and changes with aging in 626 asymptomatic individuals. / 02.2018 / PubMed / Full text
An Evaluation of Functional Sit-to-Stand Power in Cohorts of Healthy Adults Aged 18-97 Years. / 04.2017 / PubMed / Full text
A Role for TIC55 as a Hydroxylase of Phyllobilins, the Products of Chlorophyll Breakdown during Plant Senescence. / 10.2016 / PubMed / Full text
Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice. / 28.08.2016 / PubMed / Full text
Demographic aspects in cervical vertebral bodies' size and shape (C3-C7): a skeletal study. / 01.2017 / PubMed / Full text
Genetic factors associated with the development of age-related macular degeneration. / 2016 / PubMed / Full text
Prediction of Cervical Endplate Size: One Size Does Not Fit All. / 01.05.2016 / PubMed / Full text
Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles. / 05.2016 / PubMed / Full text
Age-related brain atrophy may be mitigated by internal jugular vein enlargement in male individuals without neurologic disease. / 03.2017 / PubMed / Full text
The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital-based clinical analysis. / 2016 / PubMed / Full text
Comparison of tetrodotoxin uptake and gene expression in the liver between juvenile and adult tiger pufferfish, Takifugu rubripes. / 01.03.2016 / PubMed / Full text
Empirically Defining Trajectories of Late-Life Cognitive and Functional Decline. / 2016 / PubMed / Full text
[Rich selenium-Banqiao-Codonopsis Pilosula mixture enhances immune function of aging mice]. / 10.2015 / PubMed
The effects of feeding β-glucan to Pangasianodon hypophthalmus on immune gene expression and resistance to Edwardsiella ictaluri. / 11.2015 / PubMed / Full text
Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline. / 23.09.2015 / PubMed / Full text
Bud-bank and tiller dynamics of co-occurring C3 caespitose grasses in mixed-grass prairie. / 09.2015 / PubMed / Full text
Stress, antioxidant defence and mucosal immune responses of the large yellow croaker Pseudosciaena crocea challenged with Cryptocaryon irritans. / 11.2015 / PubMed / Full text
NADPH oxidase-derived production of reactive oxygen species is involved in learning and memory impairments in 16-month-old female rats. / 09.2015 / PubMed / Full text
Effects of a recombinant complement component C3b functional fragment α2MR (α2-macroglobulin receptor) additive on the immune response of juvenile orange-spotted grouper (Epinephelus coioides) after the exposure to cold shock challenge. / 08.2015 / PubMed / Full text
Serum C3 epimer of 25-hydroxyvitamin D and its determinants in adults: a national health examination survey in Thais. / 09.2015 / PubMed / Full text
Age-Related Changes in Pharyngeal Lumen Size: A Retrospective MRI Analysis. / 06.2015 / PubMed / Full text
Age, gender and normalization covariates for spinal cord gray matter and total cross-sectional areas at cervical and thoracic levels: A 2D phase sensitive inversion recovery imaging study. / 2015 / PubMed / Full text
Genetic analysis of intracapillary glomerular lipoprotein deposits in aging mice. / 2014 / PubMed / Full text
Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol. / 2014 / PubMed / Full text
Analysis of immunoglobulin, complements and CRP levels in serum of captive northern pig-tailed macaques (Macaca leonina). / 05.2014 / PubMed / Full text
Synthesis and propagation of complement C3 by microglia/monocytes in the aging retina. / 2014 / PubMed / Full text
Molecular composition of the alveolar lining fluid in the aging lung. / 06.2014 / PubMed / Full text
Ovariectomy and subsequent treatment with estrogen receptor agonists tune the innate immune system of the hippocampus in middle-aged female rats. / 2014 / PubMed / Full text
Spontaneous age-related cervical disc degeneration in the sand rat. / 06.2014 / PubMed / Full text
New software for cervical vertebral geometry assessment and its relationship to skeletal maturation--a pilot study. / 2014 / PubMed / Full text
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. / 11.2013 / PubMed / Full text
Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration. / 11.2013 / PubMed / Full text
[Effects of Gansu Dangshen decoction on the immune function of D-galactose induced aging mice]. / 08.2013 / PubMed
A dramatic increase of C1q protein in the CNS during normal aging. / 14.08.2013 / PubMed / Full text
Aging affects high-density lipoprotein composition and function. / 09.2013 / PubMed / Full text
Influence of aging on ethanol-induced oxidative stress in digestive tract of rats. / 07.2013 / PubMed / Full text
Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation. / 10.2013 / PubMed / Full text
Developmental biomechanics of the human cervical spine. / 05.04.2013 / PubMed / Full text

Aging genes 70-79

TERT[править]

STAT3[править]

DBP[править]

H2AX[править]

NLRP3[править]

F2[править]

CAD[править]

C3[править]

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