Aging genes 1-4
DBIПравить
- Quantifying cumulative anticholinergic and sedative drug load among US Medicare Beneficiaries. / 01.10.2020 / PubMed / Full text
- Drug Burden Index and Cognitive and Physical Function in Aged Care Residents: A Longitudinal Study. / 08.2020 / PubMed / Full text
- Using the Drug Burden Index to identify older adults at highest risk for medication-related falls. / 12.06.2020 / PubMed / Full text
- Impact of STEADI-Rx: A Community Pharmacy-Based Fall Prevention Intervention. / 08.2020 / PubMed / Full text
MOSПравить
- Effect of mannan oligosaccharides on the microbiota and productivity parameters of Litopenaeus vannamei shrimp under intensive cultivation in Ecuador. / 17.02.2020 / PubMed / Full text
- Predictors of health-related quality of life among older adults living with HIV in Thailand: results from the baseline and follow-up surveys. / 23.12.2019 / PubMed / Full text
- Comparison of health-related quality of life between the Han and Yi ethnicity elderly in the Yi autonomous areas of Yunnan Province. / 25.11.2019 / PubMed / Full text
- Mannan oligosaccharide increases the growth performance, immunity and resistance capability against Vibro Parahemolyticus in juvenile abalone Haliotis discus hannai Ino. / 11.2019 / PubMed / Full text
RETПравить
- Effects of resistance exercise training on redox homeostasis in older adults. A systematic review and meta-analysis. / 09.2020 / PubMed / Full text
- Effects of an 8-week resistance training intervention on plantar flexor muscle quality and functional capacity in older women: A randomised controlled trial. / 09.2020 / PubMed / Full text
- Resistance exercise training promotes fiber type-specific myonuclear adaptations in older adults. / 01.04.2020 / PubMed / Full text
- Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults. / 11.2019 / PubMed / Full text
METПравить
- Self-rated health in relation to fruit and vegetable consumption and physical activity among older cancer survivors. / 26.09.2020 / PubMed / Full text
- Leisure-time physical activity volume, intensity, and duration from mid- to late-life in U.S. subpopulations by race and sex. The Atherosclerosis Risk In Communities (ARIC) Study. / 13.03.2020 / PubMed / Full text
- Repressive H3K9me2 protects lifespan against the transgenerational burden of COMPASS activity in [i]C. elegans[/i]. / 09.12.2019 / PubMed / Full text
- Influence of Anthropometrics on Step-Rate Thresholds for Moderate and Vigorous Physical Activity in Older Adults: Scientific Modeling Study. / 13.12.2018 / PubMed / Full text
SFNПравить
- The phytoprotective agent sulforaphane prevents inflammatory degenerative diseases and age-related pathologies via Nrf2-mediated hormesis. / 04.11.2020 / PubMed / Full text
- Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice. / 29.09.2020 / PubMed / Full text
- Sulforaphane controls the release of paracrine factors by keratinocytes and thus mitigates particulate matter-induced premature skin aging by suppressing melanogenesis and maintaining collagen homeostasis. / 10.2020 / PubMed / Full text
- Sulforaphane Inhibits Autophagy and Induces Exosome-Mediated Paracrine Senescence via Regulating mTOR/TFE3. / 07.2020 / PubMed / Full text
MFIПравить
- The Influence of the Accelerated Aging Conditions on the Properties of Polyolefin Geogrids Used for Landfill Slope Reinforcement. / 20.08.2020 / PubMed / Full text
- Changes in Physical Meat Traits, Protein Solubility, and the Microstructure of Different Beef Muscles during Post-Mortem Aging. / 19.06.2020 / PubMed / Full text
- Effect of a low-voltage electrical stimulation on yak meat tenderness during postmortem aging. / 01-12.2020 / PubMed / Full text
- Comparative effects of dry-aging and wet-aging on physicochemical properties and digestibility of Hanwoo beef. / 03.2020 / PubMed / Full text
CD27Править
- The Interplay between CD27 and CD27 B Cells Ensures the Flexibility, Stability, and Resilience of Human B Cell Memory. / 03.03.2020 / PubMed / Full text
- CMV-independent increase in CD27-CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians. / 2020 / PubMed / Full text
- Compartmentalized cytotoxic immune response leads to distinct pathogenic roles of natural killer and senescent CD8 T cells in human cutaneous leishmaniasis. / 04.2020 / PubMed / Full text
- CD27- IgD- B cell memory subset associates with inflammation and frailty in elderly individuals but only in males. / 2019 / PubMed / Full text
TP53Править
- p53 inhibits the osteogenic differentiation but does not induce senescence in human dental follicle cells. / 07-08.2020 / PubMed / Full text
- Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals. / 02.04.2020 / PubMed / Full text
- TP53/miR-34a-associated signaling targets [i]SERPINE1[/i] expression in human pancreatic cancer. / 27.01.2020 / PubMed / Full text
- Expression of p16 in nodular fasciitis: an implication for self-limited and inflammatory nature of the lesion. / 2019 / PubMed / Full text
EZH2Править
- Linking gene expression and phenotypic changes in the developmental and evolutionary origins of osteosclerosis in the ribs of bowhead whales (Balaena mysticetus). / 09.2020 / PubMed / Full text
- EZH2 is involved in vulnerability to neuroinflammation and depression-like behaviors induced by chronic stress in different aged mice. / 01.07.2020 / PubMed / Full text
- A positive feedback loop between EZH2 and NOX4 regulates nucleus pulposus cell senescence in age-related intervertebral disc degeneration. / 2020 / PubMed / Full text
- Perinatal exposure to bisphenol A impacts in the mammary gland morphology of adult Mongolian gerbils. / 04.2020 / PubMed / Full text
TET2Править
- Non-coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases. / 07.05.2020 / PubMed / Full text
- 60 Years of clonal hematopoiesis research: From X-chromosome inactivation studies to the identification of driver mutations. / 03.2020 / PubMed / Full text
- DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways. / 16.12.2019 / PubMed / Full text
- Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease. / 03.2020 / PubMed / Full text
JAK2Править
- Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity. / 2020 / PubMed / Full text
- Quercetin Directly Targets JAK2 and PKCδ and Prevents UV-Induced Photoaging in Human Skin. / 23.10.2019 / PubMed / Full text
- [Red blood cell lifespan detected by endogenous carbon monoxide breath test in patients with polycythemia vera]. / 01.10.2019 / PubMed / Full text
- Roles of JAK2 in Aging, Inflammation, Hematopoiesis and Malignant Transformation. / 08.08.2019 / PubMed / Full text
CD14Править
- Human innate immune cell crosstalk induces melanoma cell senescence. / 30.08.2020 / PubMed / Full text
- Fusion Potential of Human Osteoclasts In Vitro Reflects Age, Menopause, and In Vivo Bone Resorption Levels of Their Donors-A Possible Involvement of DC-STAMP. / 02.09.2020 / PubMed / Full text
- Association of CD14 with incident dementia and markers of brain aging and injury. / 21.01.2020 / PubMed / Full text
- Compromised Bone Healing in Aged Rats Is Associated With Impaired M2 Macrophage Function. / 2019 / PubMed / Full text
SHBGПравить
- Endogenous Testosterone Levels and the Risk of Incident Cardiovascular Events in Elderly Men: The MrOS Prospective Study. / 01.05.2020 / PubMed / Full text
- Associations of Endogenous Sex Hormones with Carotid Plaque Burden and Characteristics in Midlife Women. / 01.04.2020 / PubMed / Full text
- Analysis of the Relationship between the Levels of Androgens and Biochemical Bone Markers in Men Aged 60-75 Years. / 22.12.2019 / PubMed / Full text
- Testosterone and Estrone Increase From the Age of 70 Years: Findings From the Sex Hormones in Older Women Study. / 01.12.2019 / PubMed / Full text
TSTПравить
- H S Donors Reverse Age-Related Gastric Malfunction Impaired Due to Fructose-Induced Injury [i]via[/i] CBS, CSE, and TST Expression. / 2020 / PubMed / Full text
- Adaptations in mechanical muscle function, muscle morphology, and aerobic power to high-intensity endurance training combined with either traditional or power strength training in older adults: a randomized clinical trial. / 05.2020 / PubMed / Full text
- Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging. / 2019 / PubMed / Full text
- Objective Sleep Duration in Older Adults: Results From The Irish Longitudinal Study on Ageing. / 01.2020 / PubMed / Full text
MIPПравить
- Inspiratory muscle training improves cerebrovascular and postural control responses during orthostatic stress in older women. / 10.2020 / PubMed / Full text
- A novel multi-marker discovery approach identifies new serum biomarkers for Parkinson's disease in older people: an EXosomes in PArkiNson Disease (EXPAND) ancillary study. / 10.2020 / PubMed / Full text
- Sexual dimorphism of physical activity on cognitive aging: Role of immune functioning. / 08.2020 / PubMed / Full text
- Comparison of balance changes after inspiratory muscle or Otago exercise training. / 2020 / PubMed / Full text
ATF6Править
- Cellular proteostasis decline in human senescence. / 30.11.2020 / PubMed / Full text
- Impact of endoplasmic reticulum stress on oocyte aging mechanisms. / 01.08.2020 / PubMed / Full text
- ER stress activates immunosuppressive network: implications for aging and Alzheimer's disease. / 05.2020 / PubMed / Full text
- Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes. / 21.01.2020 / PubMed / Full text
S100A9Править
- Cigarette smoke induction of S100A9 contributes to chronic obstructive pulmonary disease. / 23.09.2020 / PubMed / Full text
- Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations. / 2020 / PubMed / Full text
- Cellular senescence induced by S100A9 in mesenchymal stromal cells through NLRP3 inflammasome activation. / 14.11.2019 / PubMed / Full text
- S100A9 extends lifespan in insulin deficiency. / 07.08.2019 / PubMed / Full text
TXNIPПравить
- Panax notoginseng saponins attenuate neuroinflammation through TXNIP-mediated NLRP3 inflammasome activation in aging rats. / 10.11.2020 / PubMed / Full text
- Redox homeostasis and cell cycle activation mediate beta-cell mass expansion in aged, diabetes-prone mice under metabolic stress conditions: Role of thioredoxin-interacting protein (TXNIP). / 07.10.2020 / PubMed / Full text
- [Effect of diabetic induced thioredoxin interacting protein (TXNIP) on islet cell senescence]. / 03.2020 / PubMed / Full text
- PRMT5-TRIM21 interaction regulates the senescence of osteosarcoma cells by targeting the TXNIP/p21 axis. / 05.02.2020 / PubMed / Full text
LBRПравить
- Lamin B receptor: role on chromatin structure, cellular senescence and possibly aging. / 31.07.2020 / PubMed / Full text
- The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers. / 03.2020 / PubMed / Full text
- The role of lamin B receptor in the regulation of senescence-associated secretory phenotype (SASP). / 01.05.2020 / PubMed / Full text
- Lamin B receptor plays a key role in cellular senescence induced by inhibition of the proteasome. / 11.12.2019 / PubMed / Full text
C3Править
- Inverse association between periumbilical fat and longevity mediated by complement C3 and cardiac structure. / 18.11.2020 / PubMed / Full text
- Complement C3 deficiency ameliorates aging related changes in the kidney. / 01.11.2020 / PubMed / Full text
- Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice. / 04.2020 / PubMed / Full text
- [Comparative analysis of experimental data about the effects of various polyphenols on lifespan and aging.] / 2019 / PubMed
LRRK2Править
- Accelerated telomere shortening independent of LRRK2 variants in Chinese patients with Parkinson's disease. / 29.10.2020 / PubMed / Full text
- The effect of LRRK2 loss-of-function variants in humans. / 06.2020 / PubMed / Full text
- Parkinson's disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging. / 19.02.2020 / PubMed / Full text
- Autophagy and LRRK2 in the Aging Brain. / 2019 / PubMed / Full text
HGFПравить
- Age-related changes in the immunomodulatory effects of human dental pulp derived mesenchymal stem cells on the CD4 T cell subsets. / 19.11.2020 / PubMed / Full text
- Hepatocyte growth factor (HGF) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling pathways. / 31.07.2020 / PubMed / Full text
- Phenytoin sodium-ameliorated gingival fibroblast aging is associated with autophagy. / 10.2020 / PubMed / Full text
- Impaired integrin α /β -mediated hepatocyte growth factor release by stellate cells of the aged liver. / 04.2020 / PubMed / Full text
STSПравить
- Delayed Impairment of Postural, Physical, and Muscular Functions Following Downhill Compared to Level Walking in Older People. / 2020 / PubMed / Full text
- Autophagy displays divergent roles during intermittent amino acid starvation and toxic stress-induced senescence in cultured skeletal muscle cells. / 06.10.2020 / PubMed / Full text
- The WRKY53 transcription factor enhances stilbene synthesis and disease resistance by interacting with MYB14 and MYB15 in Chinese wild grape. / 30.05.2020 / PubMed / Full text
- On the role of ageing and musculoskeletal pain on dynamic balance in manual workers. / 02.2020 / PubMed / Full text
CDK6Править
- Saturated Fatty Acids Promote Hepatocytic Senecence through Regulation of miR-34a/Cyclin-Dependent Kinase 6. / 24.09.2020 / PubMed / Full text
- Hepatoprotective effects of hydroxysafflor yellow A in D-galactose-treated aging mice. / 15.08.2020 / PubMed / Full text
- Anti-cell growth and anti-cancer stem cell activity of the CDK4/6 inhibitor palbociclib in breast cancer cells. / 05.2020 / PubMed / Full text
- Compromising the constitutive p16 expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence. / 04.2020 / PubMed / Full text
IGF1Править
- Genetic differences and longevity-related phenotypes influence lifespan and lifespan variation in a sex-specific manner in mice. / 11.2020 / PubMed / Full text
- 17α-estradiol modulates IGF1 and hepatic gene expression in a sex-specific manner. / 28.08.2020 / PubMed / Full text
- Pan-mammalian analysis of molecular constraints underlying extended lifespan. / 11.02.2020 / PubMed / Full text
- 17α-Estradiol promotes ovarian aging in growth hormone receptor knockout mice, but not wild-type littermates. / 01.2020 / PubMed / Full text
ERCC1Править
- Chronic Sildenafil Treatment Improves Vasomotor Function in a Mouse Model of Accelerated Aging. / 30.06.2020 / PubMed / Full text
- Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction. / 17.04.2020 / PubMed / Full text
- Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice. / 03.2020 / PubMed / Full text
- Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin. / 03.2020 / PubMed / Full text
FHПравить
- Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study. / 2020 / PubMed / Full text
- Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia. / 07.2020 / PubMed / Full text
- Macroscopic hematuria as a risk factor for hypertension in ageing people with hemophilia and a family history of hypertension. / 02.2020 / PubMed / Full text
- LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis. / 2020 / PubMed / Full text
BRAFПравить
- Conditional reprograming culture conditions facilitate growth of lower grade glioma models. / 01.12.2020 / PubMed / Full text
- Active notch protects MAPK activated melanoma cell lines from MEK inhibitor cobimetinib. / 14.11.2020 / PubMed / Full text
- Mitochondrial metabolic reprograming via BRAF inhibition ameliorates senescence. / 15.10.2019 / PubMed / Full text
ARCПравить
- The Polymorphism rs2968 of [i]LSS[/i] Gene Confers Susceptibility to Age-Related Cataract. / 11.2020 / PubMed / Full text
- Decreased Anti-Müllerian hormone and Anti-Müllerian hormone receptor type 2 in hypothalami of old Japanese Black cows. / 19.08.2020 / PubMed / Full text
- Resveratrol delay the cataract formation against naphthalene-induced experimental cataract in the albino rats. / 01.2020 / PubMed / Full text
CPMПравить
- Test-Retest Instability of Temporal Summation and Conditioned Pain Modulation Measures in Older Adults. / 21.10.2020 / PubMed / Full text
- Age does not affect sex effect of conditioned pain modulation of pressure and thermal pain across 2 conditioning stimuli. / 01-02.2020 / PubMed / Full text
- The Decline of Endogenous Pain Modulation With Aging: A Meta-Analysis of Temporal Summation and Conditioned Pain Modulation. / 05-06.2020 / PubMed / Full text
PAHПравить
- Changes in light absorption by brown carbon in soot particles due to heterogeneous ozone aging in a smog chamber. / 11.2020 / PubMed / Full text
- Factors associated with pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc). / 09.2020 / PubMed / Full text
- Potentially Avoidable Hospitalization among Long-Term Care Insurance Beneficiaries with Dementia. / 09.2020 / PubMed / Full text
DNMT3AПравить
- Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells. / 09.09.2020 / PubMed / Full text
- Collagens and DNA methyltransferases in mare endometrosis. / 09.2019 / PubMed / Full text
- Age-related clonal haemopoiesis is associated with increased epigenetic age. / 19.08.2019 / PubMed / Full text
TNCПравить
- Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging. / 18.11.2020 / PubMed / Full text
- Tenascin-C expression controls the maturation of articular cartilage in mice. / 17.02.2020 / PubMed / Full text
- Effects of hydrothermal aging, thermal cycling, and water storage on the mechanical properties of a machinable resin-based composite containing nano-zirconia fillers. / 02.2020 / PubMed / Full text
NRASПравить
- Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor. / 10.2020 / PubMed / Full text
- STAT3 Relays a Differential Response to Melanoma-Associated [i]NRAS[/i] Mutations. / 02.01.2020 / PubMed / Full text
- Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study. / 08.11.2019 / PubMed / Full text
FABP3Править
- FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging. / 09.11.2020 / PubMed / Full text
- Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3. / 04.11.2020 / PubMed / Full text
- Myokines as biomarkers of frailty and cardiovascular disease risk in females. / 05.2020 / PubMed / Full text
IL10Править
- The beneficial effect of physical exercise on inflammatory makers in older individuals. / 06.06.2020 / PubMed / Full text
- Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14 , and TAU3 transcript expression and contribute to cognitive decline. / 10.2019 / PubMed / Full text
- Dietary Spray-Dried Porcine Plasma Prevents Cognitive Decline in Senescent Mice and Reduces Neuroinflammation and Oxidative Stress. / 01.02.2020 / PubMed / Full text
CD47Править
- Aging-associated changes in CD47 arrangement and interaction with thrombospondin-1 on red blood cells visualized by super-resolution imaging. / 10.2020 / PubMed / Full text
- CD47 Promotes Age-Associated Deterioration in Angiogenesis, Blood Flow and Glucose Homeostasis. / 15.07.2020 / PubMed / Full text
- Unique Spatial Immune Profiling in Pancreatic Ductal Adenocarcinoma with Enrichment of Exhausted and Senescent T Cells and Diffused CD47-SIRPα Expression. / 07.07.2020 / PubMed / Full text
IMPACTПравить
- Load-dependent modulation of alpha oscillations during working memory encoding and retention in young and older adults. / 03.11.2020 / PubMed / Full text
- Using Video Telehealth to Deliver Patient-Centered Collaborative Care: The G-IMPACT Pilot. / 31.03.2020 / PubMed / Full text
- AGING, HEART RATE VARIABILITY AND METABOLIC IMPACT OF OBESITY. / 09.2019 / PubMed / Full text
STAT1Править
- STAT1-p53-p21axis-dependent stress-induced progression of chronic nephrosis in adriamycin-induced mouse model. / 08.2020 / PubMed / Full text
- Age-Dependent and -Independent Effects of Perivascular Adipose Tissue and Its Paracrine Activities during Neointima Formation. / 31.12.2019 / PubMed / Full text
- Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activation. / 01.03.2020 / PubMed / Full text
VDRПравить
- 25-Hydroxyvitamin D positively regulates periodontal inflammaging via SOCS3/STAT signaling in diabetic mice. / 04.2020 / PubMed / Full text
- 1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel VDR-Ezh2-p16 signal axis. / 02.2020 / PubMed / Full text
- Active vitamin D impedes the progression of non-alcoholic fatty liver disease by inhibiting cell senescence in a rat model. / 09.2020 / PubMed / Full text
CA3Править
- Features of Postnatal Hippocampal Development in a Rat Model of Sporadic Alzheimer's Disease. / 2020 / PubMed / Full text
- Age-Related Changes in Synaptic Plasticity Associated with Mossy Fiber Terminal Integration during Adult Neurogenesis. / 05-06.2020 / PubMed / Full text
- Metabotropic Glutamate Receptors at the Aged Mossy Fiber - CA3 Synapse of the Hippocampus. / 07.01.2020 / PubMed / Full text
DMDПравить
- Aldehyde dehydrogenases contribute to skeletal muscle homeostasis in healthy, aging, and Duchenne muscular dystrophy patients. / 08.2020 / PubMed / Full text
- Life expectancy at birth in Duchenne muscular dystrophy: a systematic review and meta-analysis. / 07.2020 / PubMed / Full text
- Renal dysfunction can occur in advanced-stage Duchenne muscular dystrophy. / 02.2020 / PubMed / Full text
MMDПравить
- Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study. / 22.11.2020 / PubMed / Full text
- Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study. / 16.09.2020 / PubMed / Full text
- Impact and Lessons From the Lifestyle Interventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability. / 04.2020 / PubMed / Full text
HSF1Править
- A Mitochondrial Stress-Specific Form of HSF1 Protects against Age-Related Proteostasis Collapse. / 28.09.2020 / PubMed / Full text
- Heat shock factor 1-mediated transcription activation of Omi/HtrA2 induces myocardial mitochondrial apoptosis in the aging heart. / 18.10.2019 / PubMed / Full text
- Multifactorial Attenuation of the Murine Heat Shock Response With Age. / 25.09.2020 / PubMed / Full text
RESTПравить
- [Brain and Neuronal Aging: Aged Brain Controls via Gene Expression Fidelity and Master Regulatory Factors]. / 2020 / PubMed / Full text
- Effect of 9 - PAHSA on cognitive dysfunction in diabetic mice and its possible mechanism. / 09.04.2020 / PubMed / Full text
- Increased REST to Optimize Life Span? / 12.2019 / PubMed / Full text
LMNB1Править
- SIRT1 - a new mammalian substrate of nuclear autophagy. / 08.12.2020 / PubMed / Full text
- Cellular senescence as a response to multiwalled carbon nanotube (MWCNT) exposure in human mesothelial cells. / 03.12.2020 / PubMed / Full text
- Inflammatory Drivers of Cardiovascular Disease: Molecular Characterization of Senescent Coronary Vascular Smooth Muscle Cells. / 2020 / PubMed / Full text
ERFПравить
- Angiotensin-Converting Enzyme Gene D/I Polymorphism in Relation to Endothelial Function and Endothelial-Released Factors in Chinese Women. / 2020 / PubMed / Full text
- Projections of Ambient Temperature- and Air Pollution-Related Mortality Burden Under Combined Climate Change and Population Aging Scenarios: a Review. / 09.2020 / PubMed / Full text
- Exome Sequencing Analysis Identifies Rare Variants in [i]ATM[/i] and [i]RPL8[/i] That Are Associated With Shorter Telomere Length. / 2020 / PubMed / Full text
PRLПравить
- Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis. / 25.08.2020 / PubMed / Full text
- Prolactin mitigates deficiencies of retinal function associated with aging. / 01.2020 / PubMed / Full text
- A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation. / 06.08.2019 / PubMed / Full text
NEDD8Править
- Targeting Protein Neddylation for Cancer Therapy. / 2020 / PubMed / Full text
- Effective targeting of the ubiquitin-like modifier NEDD8 for lung adenocarcinoma treatment. / 08.2020 / PubMed / Full text
- Pevonedistat targeted therapy inhibits canine melanoma cell growth through induction of DNA re-replication and senescence. / 09.2020 / PubMed / Full text
EDAПравить
- Interplay between aging, lung inflammation/remodeling, and fibronectin EDA in lung cancer progression. / 01.12.2020 / PubMed / Full text
- Arousal Detection in Elderly People from Electrodermal Activity Using Musical Stimuli. / 25.08.2020 / PubMed / Full text
- The structure of agricultural microplastics (PT, PU and UF) and their sorption capacities for PAHs and PHE derivates under various salinity and oxidation treatments. / 02.2020 / PubMed / Full text
PFASПравить
- Associations between serum concentrations of perfluoroalkyl substances and DNA methylation in women exposed through drinking water: A pilot study in Ronneby, Sweden. / 12.2020 / PubMed / Full text
- Perfluorinated alkyl substances impede growth, reproduction, lipid metabolism and lifespan in Daphnia magna. / 01.10.2020 / PubMed / Full text
- The effect of weathering on per- and polyfluoroalkyl substances (PFASs) from durable water repellent (DWR) clothing. / 06.2020 / PubMed / Full text
P2RY12Править
- Potential caveats of putative microglia-specific markers for assessment of age-related cerebrovascular neuroinflammation. / 01.12.2020 / PubMed / Full text
- Microglial changes in the early aging stage in a healthy retina and an experimental glaucoma model. / 2020 / PubMed / Full text
- Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains. / 20.01.2020 / PubMed / Full text
G6PDПравить
- G6PD overexpression protects from oxidative stress and age-related hearing loss. / 22.11.2020 / PubMed / Full text
- The Sickle Effect: The Silent Titan Affecting Glycated Hemoglobin Reliability. / 12.08.2020 / PubMed / Full text
- DNA damage and synaptic and behavioural disorders in glucose-6-phosphate dehydrogenase-deficient mice. / 01.2020 / PubMed / Full text
C9Править
- C9orf72 in myeloid cells suppresses STING-induced inflammation. / 09.2020 / PubMed / Full text
- Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain. / 16.12.2019 / PubMed / Full text
- Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity. / 12.2019 / PubMed / Full text
CD81Править
- Ovarian aging increases small extracellular vesicle CD81 release in human follicular fluid and influences miRNA profiles. / 17.06.2020 / PubMed / Full text
- Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature. / 15.04.2020 / PubMed / Full text
- Increased production of functional small extracellular vesicles in senescent endothelial cells. / 04.2020 / PubMed / Full text
CTRLПравить
- Aging reduces the maximal level of peripheral fatigue tolerable and impairs exercise capacity. / 01.12.2020 / PubMed / Full text
- miR-146a Plasma Levels Are Not Altered in Alzheimer's Disease but Correlate With Age and Illness Severity. / 2019 / PubMed / Full text
- Centrally-mediated regulation of peripheral fatigue during knee extensor exercise and consequences on the force-duration relationship in older men. / 06.2020 / PubMed / Full text
TREM2Править
- Loss of TREM2 Confers Resilience to Synaptic and Cognitive Impairment in Aged Mice. / 09.12.2020 / PubMed / Full text
- Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer's Disease Brain. / 2020 / PubMed / Full text
- Knockdown of astrocytic TREM2 in the hippocampus relieves cognitive decline in elderly male mice. / 15.01.2021 / PubMed / Full text
TPRПравить
- Catalytic Performances of Cu/MCM-22 Zeolites with Different Cu Loadings in NH -SCR. / 30.10.2020 / PubMed / Full text
- Do traits of plant species predict the efficacy of species distribution models for finding new occurrences? / 06.2020 / PubMed / Full text
- In-situ modified the surface of Pt-doped perovskite catalyst for soot oxidation. / 05.02.2020 / PubMed / Full text
PAMПравить
- Relationship between patient activation measurement and self-rated health in patients with chronic diseases. / 04.11.2020 / PubMed / Full text
- Reversal of Age-Related Neuronal Atrophy by α5-GABAA Receptor Positive Allosteric Modulation. / 17.10.2020 / PubMed / Full text
- The ratio of prematurely aging to non-prematurely aging mice cohabiting, conditions their behavior, immunity and lifespan. / 15.06.2020 / PubMed / Full text
CD36Править
- Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease. / 08.2020 / PubMed / Full text
- Reduction of senescence-associated beta-galactosidase activity by vitamin E in human fibroblasts depends on subjects' age and cell passage number. / 07.2020 / PubMed / Full text
- Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. / 05.2020 / PubMed / Full text
SOD1Править
- SOD1, more than just an antioxidant. / 28.11.2020 / PubMed / Full text
- The Exacerbation of Aging and Oxidative Stress in the Epididymis of [i]Sod1[/i] Null Mice. / 11.02.2020 / PubMed / Full text
- Alterations in lipid metabolism of spinal cord linked to amyotrophic lateral sclerosis. / 12.08.2019 / PubMed / Full text
MDM2Править
- SENEBLOC, a long non-coding RNA suppresses senescence via p53-dependent and independent mechanisms. / 06.04.2020 / PubMed / Full text
- Disruption of Robo2-Baiap2 integrated signaling drives cystic disease. / 19.09.2019 / PubMed / Full text
- Senescence-induced immunophenotype, gene expression and electrophysiology changes in human amniocytes. / 11.2019 / PubMed / Full text
CCN1Править
- Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis. / 09.2020 / PubMed / Full text
- Inhibition of cellular communication network factor 1 (CCN1)-driven senescence slows down cartilage inflammaging and osteoarthritis. / 10.2020 / PubMed / Full text
- The senescence-associated matricellular protein CCN1 in plasma of human subjects with idiopathic pulmonary fibrosis. / 01.2020 / PubMed / Full text
SOX2Править
- Multiple nanosecond pulsed electric fields stimulation with conductive poly(l-lactic acid)/carbon nanotubes films maintains the multipotency of mesenchymal stem cells during prolonged in vitro culture. / 08.2020 / PubMed / Full text
- Subpopulations of miniature pig mesenchymal stromal cells with different differentiation potentials differ in the expression of octamer-binding transcription factor 4 and sex determining region Y-box 2. / 03.2020 / PubMed / Full text
- Increased Type I and Decreased Type II Hair Cells after Deletion of Sox2 in the Developing Mouse Utricle. / 01.12.2019 / PubMed / Full text
MCCПравить
- Multiple chronic conditions and risk of cognitive impairment and dementia among older Americans: findings from the Aging, Demographics, and Memory Study (ADAMS). / 07.07.2020 / PubMed / Full text
- Behaviour consistency is a sensitive tool for distinguishing the effects of aging on physical activity. / 01.07.2020 / PubMed / Full text
- Burden on Caregivers of Adults with Multiple Chronic Conditions: Intersectionality of Age, Gender, Education level, Employment Status, and Impact on Social Life. / 09.2020 / PubMed / Full text
ARNTПравить
- Loss of ARNT in skeletal muscle limits muscle regeneration in aging. / 12.2020 / PubMed / Full text
- [Arylhydrocarbon receptor nuclear translocator (ARNT) in human skin during aging.] / 2020 / PubMed
- The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1. / 03.04.2020 / PubMed / Full text
NAMPTПравить
- Over-expression of Nicotinamide phosphoribosyltransferase in mouse cells confers protective effect against oxidative and ER stress-induced premature senescence. / 08.2020 / PubMed / Full text
- Resistance training increases muscle NAD and NADH concentrations as well as NAMPT protein levels and global sirtuin activity in middle-aged, overweight, untrained individuals. / 05.05.2020 / PubMed / Full text
- Differential Expression of Human N-Alpha-Acetyltransferase 40 (hNAA40), Nicotinamide Phosphoribosyltransferase (NAMPT) and Sirtuin-1 (SIRT-1) Pathway in Obesity and T2DM: Modulation by Metformin and Macronutrient Intake. / 2019 / PubMed / Full text
CXCR4Править
- Aging-Related Reduced Expression of CXCR4 on Bone Marrow Mesenchymal Stromal Cells Contributes to Hematopoietic Stem and Progenitor Cell Defects. / 08.2020 / PubMed / Full text
- Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway. / 09.2020 / PubMed / Full text
- Stromal Cell-Derived Factor 1 Protects Brain Vascular Endothelial Cells from Radiation-Induced Brain Damage. / 10.10.2019 / PubMed / Full text
MTORПравить
- The roles of MTOR and miRNAs in endothelial cell senescence. / 10.2020 / PubMed / Full text
- Autophagy drives fibroblast senescence through MTORC2 regulation. / 11.2020 / PubMed / Full text
- The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan. / 09.2020 / PubMed / Full text
BRD4Править
- Inhibition of BRD4 triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells. / 20.09.2020 / PubMed / Full text
- BRD4 contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake. / 11.05.2020 / PubMed / Full text
- BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes. / 26.09.2019 / PubMed / Full text
CXCL12Править
- Co-option of Neutrophil Fates by Tissue Environments. / 25.11.2020 / PubMed / Full text
- Heme oxygenase-1 deficiency triggers exhaustion of hematopoietic stem cells. / 05.02.2020 / PubMed / Full text
- Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation. / 03.12.2019 / PubMed / Full text
SLAПравить
- Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity. / 14.07.2020 / PubMed / Full text
- Mechanical Anisotropy and Surface Roughness in Additively Manufactured Parts Fabricated by Stereolithography (SLA) Using Statistical Analysis. / 30.05.2020 / PubMed / Full text
- The Effect of Age of Titanium Dental Implants on Implant Survival and Marginal Bone Resorption: A 5-Year Retrospective Follow-Up Study. / 01.10.2020 / PubMed / Full text
ASLПравить
- Increased blood-brain barrier permeability to water in the aging brain detected using noninvasive multi-TE ASL MRI. / 01.2021 / PubMed / Full text
- Quantitative Cerebrovascular Reactivity in Normal Aging: Comparison Between Phase-Contrast and Arterial Spin Labeling MRI. / 2020 / PubMed / Full text
- Correcting Task fMRI Signals for Variability in Baseline CBF Improves BOLD-Behavior Relationships: A Feasibility Study in an Aging Model. / 2020 / PubMed / Full text
DPP4Править
- Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis. / 2020 / PubMed / Full text
- Dipeptidyl peptidase-4 inhibition improves endothelial senescence by activating AMPK/SIRT1/Nrf2 signaling pathway. / 07.2020 / PubMed / Full text
- Molecular crosstalk between Y5 receptor and neuropeptide Y drives liver cancer. / 01.05.2020 / PubMed / Full text
CA2Править
- Maintaining Aging Hippocampal Function with Safe and Feasible Shaking Exercise in SAMP10 Mice. / 2020 / PubMed / Full text
- One-year Follow-up Study of Hippocampal Subfield Atrophy in Alzheimer's Disease and Normal Aging. / 2019 / PubMed / Full text
- Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory. / 29.10.2019 / PubMed / Full text
SSTПравить
- The distance to death perceptions of older adults explain why they age in place: A theoretical examination. / 09.2020 / PubMed / Full text
- Population Segmentation Based on Healthcare Needs: Validation of a Brief Clinician-Administered Tool. / 30.06.2020 / PubMed / Full text
- Examination on how emotion regulation mediates the relationship between future time perspective and well-being: a counter-evidence to the socioemotional selectivity theory. / 03.2020 / PubMed / Full text
GRK2Править
- G protein-coupled receptor kinase 2 modifies the ability of Caenorhabditis elegans to survive oxidative stress. / 16.10.2020 / PubMed / Full text
- G protein coupled receptor kinases modulate Caenorhabditis elegans reactions to heat stresses. / 01.10.2020 / PubMed / Full text
- Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging. / 01.05.2020 / PubMed / Full text
AIPПравить
- [Aryl hydrocarbon receptor interacting protein (AIP) in human dermis during aging.] / 2020 / PubMed
- Sex-Specific Association between Serum Vitamin D Status and Lipid Profiles: A Cross-Sectional Study of a Middle-Aged and Elderly Chinese Population. / 2020 / PubMed / Full text
- The oblique effect: The relationship between profiles of visuospatial preference, cognition, and brain connectomics in older adults. / 12.2019 / PubMed / Full text
PSDПравить
- Quantitative Immunoblotting Analyses Reveal that the Abundance of Actin, Tubulin, Synaptophysin and EEA1 Proteins is Altered in the Brains of Aged Mice. / 21.08.2020 / PubMed / Full text
- Exercise Attenuates Brain Aging by Rescuing Down-Regulated Wnt/β-Catenin Signaling in Aged Rats. / 2020 / PubMed / Full text
- Concurrent nicotine exposure to prenatal alcohol consumption alters the hippocampal and cortical neurotoxicity. / 01.2020 / PubMed / Full text
FAPПравить
- Rapamycin Extends Life Span in Apc Colon Cancer FAP Model. / 15.09.2020 / PubMed / Full text
- Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors. / 14.02.2020 / PubMed / Full text
- Control of Muscle Fibro-Adipogenic Progenitors by Myogenic Lineage is Altered in Aging and Duchenne Muscular Dystrophy. / 2019 / PubMed / Full text
IRS1Править
- MicroRNA-34a causes ceramide accumulation and effects insulin signaling pathway by targeting ceramide kinase (CERK) in aging skeletal muscle. / 06.2020 / PubMed / Full text
- Longevity in response to lowered insulin signaling requires glycine N-methyltransferase-dependent spermidine production. / 01.2020 / PubMed / Full text
- Serine Phosphorylation of IRS1 Correlates with Aβ-Unrelated Memory Deficits and Elevation in Aβ Level Prior to the Onset of Memory Decline in AD. / 17.08.2019 / PubMed / Full text
SMSПравить
- Does a Live Performance Impact Synchronization to Musical Rhythm in Cognitively Impaired Elderly? / 2020 / PubMed / Full text
- Testing the effectiveness of physical activity advice delivered via text messaging vs. human phone advisors in a Latino population: The On The Move randomized controlled trial design and methods. / 08.2020 / PubMed / Full text
GPX4Править
IGFBP3Править
IQGAP1Править
TLR1Править
MPIПравить
EPOПравить
CXCR2Править
TLR2Править
AHRПравить
- Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging. / 01.09.2020 / PubMed / Full text
- Role of the Aryl Hydrocarbon Receptor in Environmentally Induced Skin Aging and Skin Carcinogenesis. / 28.11.2019 / PubMed / Full text
C6Править
HMGA2Править
BACE1Править
C2Править
CYP2C19Править
- Physiologically Based Pharmacokinetic Approach Can Successfully Predict Pharmacokinetics of Citalopram in Different Patient Populations. / 04.2020 / PubMed / Full text
- Longitudinal exposure of English primary care patients to pharmacogenomic drugs: An analysis to inform design of pre-emptive pharmacogenomic testing. / 12.2019 / PubMed / Full text
SDC1Править
C5Править
- The C5-75 Program: Meeting the Need for Efficient, Pragmatic Frailty Screening and Management in Primary Care. / 23.06.2020 / PubMed / Full text
- Can a relatively large spinal cord for the dural sac influence severity of paralysis in elderly patients with cervical spinal cord injury caused by minor trauma? / 26.06.2020 / PubMed / Full text
MMEПравить
DRD2Править
- Cortical thickness mediates the relationship between DRD2 C957T polymorphism and executive function across the adult lifespan. / 11.11.2020 / PubMed / Full text
- The relationship of age and DRD2 polymorphisms to frontostriatal brain activity and working memory performance. / 12.2019 / PubMed / Full text
LPLПравить
ELOVL2Править
CSF1RПравить
- CSF1R inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice. / 02.02.2020 / PubMed / Full text
- Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units. / 05.11.2019 / PubMed / Full text
PMLПравить
FSHRПравить
- FSHR ablation induces depression-like behaviors. / 08.2020 / PubMed / Full text
- Direct actions of gonadotropins beyond the reproductive system and their role in human aging and neoplasia [Bezpośrednie działanie gonadotropin poza układem rozrodczym i ich rola w starzeniu się i nowotworzeniu u człowieka]. / 2019 / PubMed / Full text
E2F1Править
MBPПравить
- Demyelination associated with chronic arsenic exposure in Wistar rats. / 15.04.2020 / PubMed / Full text
- Natural killer cells as participants in pathogenesis of rat experimental autoimmune encephalomyelitis (EAE): lessons from research on rats with distinct age and strain. / 2019 / PubMed / Full text
ABCG2Править
- Contribution of senescence in human endometrial stromal cells during proliferative phase to embryo receptivity†. / 23.06.2020 / PubMed / Full text
- ABCG2 rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population. / 17.03.2020 / PubMed / Full text
SPARCПравить
- SPARC Metrics Provide Mobility Smoothness Assessment in Oldest-Old With and Without a History of Falls: A Case Control Study. / 2020 / PubMed / Full text
- Reduced fibrillar collagen accumulation in skeletal muscle of secreted protein acidic and rich in cysteine (SPARC)-null mice. / 29.11.2019 / PubMed / Full text
LTAПравить
- Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice. / 02.2020 / PubMed / Full text
- The change of pain classes over time: a latent transition analysis. / 02.2020 / PubMed / Full text
ERGПравить
- Effect of age and sex on neurodevelopment and neurodegeneration in the healthy eye: Longitudinal functional and structural study in the Long-Evans rat. / 11.2020 / PubMed / Full text
- Mice With a Combined Deficiency of Superoxide Dismutase 1 (Sod1), DJ-1 (Park7), and Parkin (Prkn) Develop Spontaneous Retinal Degeneration With Aging. / 03.09.2019 / PubMed / Full text
NPR1Править
- The NPR1-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana. / 03.12.2020 / PubMed / Full text
- Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis. / 07.2020 / PubMed / Full text
LEPПравить
POT1Править
FGAПравить
SYKПравить
NNTПравить
- Yoga, Health-Related Quality of Life and Mental Well-Being: A Re-analysis of a Meta-analysis Using the Quality Effects Model. / 16.09.2020 / PubMed / Full text
- Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database. / 02.2020 / PubMed / Full text
VDAC1Править
LSSПравить
- Surgical results in older patients with lumbar spinal stenosis according to gait speed in relation to the diagnosis for sarcopenia. / 01-04.2020 / PubMed / Full text
- Streamlining an existing hip fracture patient pathway in an acute tertiary adult Irish hospital to improve patient experience and outcomes. / 22.12.2019 / PubMed / Full text
OGTПравить
VIPПравить
CX3CR1Править
CDAПравить
DCXПравить
MCUПравить
- A rare case of Epstein-Barr virus-positive mucocutaneous ulcer that developed into an intestinal obstruction: a case report. / 13.01.2020 / PubMed / Full text
- Inhibition of Mitochondrial Calcium Overload by SIRT3 Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue. / 02.2020 / PubMed / Full text
BAXПравить
- Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-X -BAX interaction. / 10.2020 / PubMed / Full text
- CREB Signaling Mediates Dose-Dependent Radiation Response in the Murine Hippocampus Two Years after Total Body Exposure. / 03.01.2020 / PubMed / Full text
HMGCRПравить
CBSПравить
- Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity. / 02.08.2020 / PubMed / Full text
- Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase. / 06.2020 / PubMed / Full text
CDK4Править
- Emerging Roles for the [i]INK4a/ARF[/i] ([i]CDKN2A[/i]) Locus in Adipose Tissue: Implications for Obesity and Type 2 Diabetes. / 22.09.2020 / PubMed / Full text
- Guilu Erxian Glue () Inhibits Chemotherapy-Induced Bone Marrow Hematopoietic Stem Cell Senescence in Mice May via p16 -Rb Signaling Pathway. / 11.2020 / PubMed / Full text
BPIПравить
PDK1Править
- Inhibition of 3-phosphoinositide-dependent protein kinase 1 (PDK1) can revert cellular senescence in human dermal fibroblasts. / 08.12.2020 / PubMed / Full text
- The Impact of the PI3K/Akt Signaling Pathway in Anxiety and Working Memory in Young and Middle-Aged PDK1 K465E Knock-In Mice. / 2020 / PubMed / Full text
CR1Править
NPYПравить
HRASПравить
GRNПравить
TRPV4Править
- TRPV4 receptor as a functional sensory molecule in bladder urothelium: Stretch-independent, tissue-specific actions and pathological implications. / 01.2020 / PubMed / Full text
- Exercise restores impaired endothelium-derived hyperpolarizing factor-mediated vasodilation in aged rat aortic arteries via the TRPV4-K 2.3 signaling complex. / 2019 / PubMed / Full text
PTHПравить
KRASПравить
- Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging. / 09.2020 / PubMed
- Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. / 16.04.2020 / PubMed / Full text
CITПравить
RIPK1Править
PCSK9Править
SPRY1Править
TSPOПравить
- Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge. / 2019 / PubMed / Full text
- Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study. / 10.11.2019 / PubMed / Full text
KLF4Править
- Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1α Activation. / 25.06.2020 / PubMed / Full text
- Soluble klotho regulates the function of salivary glands by activating KLF4 pathways. / 02.10.2019 / PubMed / Full text
INSПравить
SAGПравить
- WRKY42 transcription factor positively regulates leaf senescence through modulating SA and ROS synthesis in Arabidopsis thaliana. / 09.2020 / PubMed / Full text
- Neurogenesis in the inner ear: the zebrafish statoacoustic ganglion provides new neurons from a Neurod/Nestin-positive progenitor pool well into adulthood. / 10.04.2020 / PubMed / Full text
JAK1Править
- Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling. / 01.05.2020 / PubMed / Full text
- The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Through JAK1. / 2019 / PubMed / Full text
F5Править
- Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis. / 02.2020 / PubMed / Full text
- Fermentation of Blackberry with [i]L. plantarum[/i] JBMI F5 Enhance the Protection Effect on UVB-Mediated Photoaging in Human Foreskin Fibroblast and Hairless Mice through Regulation of MAPK/NF-κB Signaling. / 11.10.2019 / PubMed / Full text
ACRПравить
TMPRSS2Править
- Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants. / 09.09.2020 / PubMed / Full text
- Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. / 03.06.2020 / PubMed / Full text
CXCL1Править
- Contusion spinal cord injury upregulates p53 protein expression in rat soleus muscle at multiple timepoints but not key senescence cytokines. / 02.2020 / PubMed / Full text
- Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy. / 2019 / PubMed / Full text
HPПравить
GATA4Править
- Epigenetics and Vascular Senescence-Potential New Therapeutic Targets? / 2020 / PubMed / Full text
- Prolonged treatment with Y-27632 promotes the senescence of primary human dermal fibroblasts by increasing the expression of IGFBP-5 and transforming them into a CAF-like phenotype. / 25.08.2020 / PubMed / Full text
ADMПравить
- Assessment of age-related differences in decomposition-based quantitative EMG in the intrinsic hand muscles: A multivariate approach. / 09.2020 / PubMed / Full text
- Evaluation of transcriptional levels of the natriuretic peptides, endothelin-1, adrenomedullin, their receptors and long non-coding RNAs in rat cardiac tissue as cardiovascular biomarkers of aging. / 01.2020 / PubMed / Full text
CCN3Править
PSEN2Править
CPT1CПравить
CFTRПравить
HDAC3Править
FNDC5Править
- Irisin Correlates Positively With BMD in a Cohort of Older Adult Patients and Downregulates the Senescent Marker p21 in Osteoblasts. / 14.10.2020 / PubMed / Full text
- [Investigation of signal molecules in saliva: prospects of application for diagnostics of myocardial infarction and the aging rate of different age people.] / 2019 / PubMed
ABOПравить
FGFR1Править
NOTCH1Править
SRFПравить
BPIFB4Править
MALT1Править
MFN2Править
- Thioredoxin protects mitochondrial structure, function and biogenesis in myocardial ischemia-reperfusion via redox-dependent activation of AKT-CREB- PGC1α pathway in aged mice. / 13.10.2020 / PubMed / Full text
- MFN2 contributes to metabolic disorders and inflammation in the aging of rat chondrocytes and osteoarthritis. / 08.2020 / PubMed / Full text
MMP1Править
- Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts. / 12.2020 / PubMed / Full text
- A novel multifunctional skin care formulation with a unique blend of antipollution, brightening and antiaging active complexes. / 06.2020 / PubMed / Full text
TBC1D5Править
ADAM10Править
PLK4Править
FASПравить
GALПравить
- Overexpression of Pitx1 attenuates the senescence of chondrocytes from osteoarthritis degeneration cartilage-A self-controlled model for studying the etiology and treatment of osteoarthritis. / 02.2020 / PubMed / Full text
- β-Caryophyllene Reduces DNA Oxidation and the Overexpression of Glial Fibrillary Acidic Protein in the Prefrontal Cortex and Hippocampus of d-Galactose-Induced Aged BALB/c Mice. / 05.2020 / PubMed / Full text
GCAПравить
PTX3Править
- Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. / 27.01.2020 / PubMed / Full text
- Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study. / 13.07.2020 / PubMed / Full text
MITFПравить
- Thymocid , a Standardized Black Cumin ([i]Nigella sativa[/i]) Seed Extract, Modulates Collagen Cross-Linking, Collagenase and Elastase Activities, and Melanogenesis in Murine B16F10 Melanoma Cells. / 19.07.2020 / PubMed / Full text
- HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth. / 21.05.2020 / PubMed / Full text
KEAP1Править
GAAПравить
RHOПравить
MIAПравить
GHRHПравить
- Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone. / 18.05.2020 / PubMed / Full text
- Transcriptomic and metabolomic profiling of long-lived growth hormone releasing hormone knock-out mice: evidence for altered mitochondrial function and amino acid metabolism. / 23.02.2020 / PubMed / Full text
PIPПравить
- Potentially inappropriate prescriptions according to explicit and implicit criteria in patients with multimorbidity and polypharmacy. MULTIPAP: A cross-sectional study. / 2020 / PubMed / Full text
- Quality of prescribing predicts hospitalisation in octogenarians: life and living in advanced age: a cohort study in New Zealand (LiLACS NZ). / 19.12.2019 / PubMed / Full text