Aging genes 100: различия между версиями

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__NOTOC__
* [[Aging genes 100‎‎|Genes with 100 and more publications]]
* [[Aging genes 100‎‎|Genes with 100 and more publications]]
* [[Aging genes 60-99‎‎|Genes with 60-99 publications]]
* [[Aging genes 60-99‎‎|Genes with 60-99 publications]]
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* {{medline-title
* {{medline-title
|title=Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA + DHA.
|title=Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA   DHA.
|date=06.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30535619
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30535619
Строка 1581: Строка 1581:
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.002
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.002
}}
}}
==CD4==
* {{medline-title
* {{medline-title
|title=Identification of Key Genes and Potential New Biomarkers for Ovarian Aging: A Study Based on RNA-Sequencing Data.
|title=Age-dependent alterations in serum cytokines, peripheral blood mononuclear cell cytokine production, natural killer cell activity, and prostaglandin F .
|date=2020
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304387
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28762199
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701310
|full-text-url=https://sci-hub.do/10.1007/s12026-017-8940-0
}}
}}
* {{medline-title
* {{medline-title
|title=Distinct Age-Related Epigenetic Signatures in [[CD4]] and CD8 T Cells.
|title=Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression.
|date=2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33262764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28744338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686576
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506461
}}
}}
* {{medline-title
* {{medline-title
|title=IL-1β-MyD88-mTOR Axis Promotes Immune-Protective IL-17A Foxp3  Cells During Mucosal Infection and Is Dysregulated With Aging.
|title=Counts of [[MSC]] in the Bone Marrow of Young and Old CBA Mice after a Single Exposure to Osteogenic Stimuli (Curettage, BMP-2 Injection) or Antigens (S. typhimurium Antigenic Complex) and in Heterotopic Bone Marrow Transplants.
|date=2020
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33240286
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28744638
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677307
|full-text-url=https://sci-hub.do/10.1007/s10517-017-3805-z
}}
}}
* {{medline-title
* {{medline-title
|title=Thymus involution sets the clock of declined immunity and repair with aging.
|title=Effect of Exercise on Inflammatory Profile of Older Persons: Systematic Review and Meta-Analyses.
|date=25.11.2020
|date=01.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33248315
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28771081
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101231
|full-text-url=https://sci-hub.do/10.1123/jpah.2016-0735
}}
}}
* {{medline-title
* {{medline-title
|title=Food insecurity and T-cell dysregulation in women living with HIV on antiretroviral therapy.
|title=Emerging role of Interleukins IL-23/IL-17 axis and biochemical markers in the pathogenesis of Type 2 Diabetes: Association with age and gender in human subjects.
|date=28.11.2020
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33247896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28757426
|full-text-url=https://sci-hub.do/10.1093/cid/ciaa1771
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2017.07.155
}}
}}
* {{medline-title
* {{medline-title
|title=Rapamycin Eyedrops Increased [[CD4]] Foxp3  Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface.
|title=An Appropriate Modulation of Lymphoproliferative Response and Cytokine Release as Possible Contributors to Longevity.
|date=24.11.2020
|date=24.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33255287
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28737707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727717
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536085
}}
}}
* {{medline-title
* {{medline-title
|title=Antioxidants N-Acetylcysteine and Vitamin C Improve T Cell Commitment to Memory and Long-Term Maintenance of Immunological Memory in Old Mice.
|title=Intestinal Permeability Biomarker Zonulin is Elevated in Healthy Aging.
|date=19.11.2020
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33228213
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699597
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581307
}}
}}
* {{medline-title
* {{medline-title
|title=Evolution of comorbidities in people living with HIV between 2004 and 2014: cross-sectional analyses from ANRS CO3 Aquitaine cohort.
|title=Tumor-targeted IL-12 combined with local irradiation leads to systemic tumor control via abscopal effects [i]in vivo[/i].
|date=16.11.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33198667
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28680762
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670698
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486191
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of age on [[CD4]] recovery and viral suppression over time among adults living with HIV who initiated antiretroviral therapy in the African Cohort Study.
|title=The relation between DNA methylation patterns and serum cytokine levels in community-dwelling adults: a preliminary study.
|date=12.11.2020
|date=21.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33183355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28637423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480116
}}
}}
* {{medline-title
* {{medline-title
|title=hPMSCs protects against D-galactose-induced oxidative damage of [[CD4]] T cells through activating Akt-mediated Nrf2 antioxidant signaling.
|title=Critical role of [[TNF]] inhibition in combination therapy for elderly mice with atherosclerosis.
|date=04.11.2020
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33148324
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28643478
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641865
|full-text-url=https://sci-hub.do/10.1111/1755-5922.12280
}}
}}
* {{medline-title
* {{medline-title
|title=Substantial gap in primary care: older adults with HIV presenting late to care.
|title=Structural characterization of a pectic polysaccharide from Codonopsis pilosula and its immunomodulatory activities in vivo and in vitro.
|date=31.10.2020
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33129258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28600205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603686
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2017.06.023
}}
}}
* {{medline-title
* {{medline-title
|title=Quantitative Digitography Measures Fine Motor Disturbances in Chronically Treated HIV Similar to Parkinson's Disease.
|title=p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling.
|date=2020
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33132893
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28607003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538795
}}
}}
* {{medline-title
* {{medline-title
|title=Monocyte and T Cell Immune Phenotypic Profiles Associated With Age Advancement Differ Between People With HIV, Lifestyle-Comparable Controls and Blood Donors.
|title=A dual agonist of farnesoid X receptor (FXR) and the G protein-coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice.
|date=2020
|date=21.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33123168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28596381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573236
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519354
}}
}}
* {{medline-title
* {{medline-title
|title=HIV and three dimensions of Wisdom: Association with cognitive function and physical and mental well-being: For: Psychiatry Research.
|title=Deregulation of hsa-miR-20b expression in [[TNF]]-α-induced premature senescence of human pulmonary microvascular endothelial cells.
|date=12.2020
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33096437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28595801
|full-text-url=https://sci-hub.do/10.1016/j.psychres.2020.113510
|full-text-url=https://sci-hub.do/10.1016/j.mvr.2017.06.002
}}
}}
* {{medline-title
* {{medline-title
|title=CD8  T cells are present at low levels in the white matter with physiological and pathological aging.
|title=Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics.
|date=13.10.2020
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33049712
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28556428
|full-text-url=https://sci-hub.do/10.18632/aging.104043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506434
}}
}}
* {{medline-title
* {{medline-title
|title=Immunotherapy in older patients with cancer.
|title=Grip strength and inflammatory biomarker profiles in very old adults.
|date=26.07.2020
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33041248
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28541423
|full-text-url=https://sci-hub.do/10.1016/j.bj.2020.07.009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860623
}}
}}
* {{medline-title
* {{medline-title
|title=Multiple genetic programs contribute to [[CD4]] T cell memory differentiation and longevity by maintaining T cell quiescence.
|title=Anti-aging drugs reduce hypothalamic inflammation in a sex-specific manner.
|date=11.2020
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32987276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28544365
|full-text-url=https://sci-hub.do/10.1016/j.cellimm.2020.104210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506421
}}
}}
* {{medline-title
* {{medline-title
|title=Conventional Treatment for Multiple Myeloma Drives Premature Aging Phenotypes and Metabolic Dysfunction in T Cells.
|title=Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-[[SIRT1]] pathway.
|date=2020
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28544111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494758
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506400
}}
}}
* {{medline-title
* {{medline-title
|title=Immunosenescence: the role of age in multiple sclerosis.
|title=Role of Adipose Tissue Endothelial [[ADAM17]] in Age-Related Coronary Microvascular Dysfunction.
|date=19.09.2020
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32962809
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473444
|full-text-url=https://sci-hub.do/10.1016/j.nrl.2020.05.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484536
}}
}}
* {{medline-title
* {{medline-title
|title=Umbilical cord mesenchymal stem cells protect thymus structure and function in aged C57 mice by downregulating aging-related genes and upregulating autophagy- and anti-oxidative stress-related genes.
|title=Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells.
|date=14.09.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32924972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439450
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521525
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391678
}}
}}
* {{medline-title
* {{medline-title
|title=Impaired Cytotoxic CD8  T Cell Response in Elderly COVID-19 Patients.
|title=Inflammatory Markers and Risk for Cognitive Decline in Chronic Kidney Disease: The CRIC Study.
|date=18.09.2020
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32948688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439566
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502863
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399682
}}
}}
* {{medline-title
* {{medline-title
|title=What are the roles of antibodies versus a durable, high quality T-cell response in protective immunity against SARS-CoV-2?
|title=Short-Term Fructose Feeding Induces Inflammation and Oxidative Stress in the Hippocampus of Young and Adult Rats.
|date=11.12.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32875286
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28455700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452821
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0518-2
}}
}}
* {{medline-title
* {{medline-title
|title=Per2 Upregulation in Circulating Hematopoietic Progenitor Cells During Chronic HIV Infection.
|title=Allogeneic Human Mesenchymal Stem Cell Infusions for Aging Frailty.
|date=2020
|date=12.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850472
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28444181
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861970
}}
}}
* {{medline-title
* {{medline-title
|title=COVID-19: age, Interleukin-6, C-reactive protein, and lymphocytes as key clues from a multicentre retrospective study.
|title=The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation.
|date=2020
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32802142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28438557
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426672
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2017.04.015
}}
}}
* {{medline-title
* {{medline-title
|title=Immunosenescence profiles are not associated with muscle strength, physical performance and sarcopenia risk in very old adults: The Newcastle 85+ Study.
|title=Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction.
|date=09.2020
|date=12.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32735896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407483
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111321
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392495
}}
}}
* {{medline-title
* {{medline-title
|title=Homeostasis and the functional roles of [[CD4]]  Treg cells in aging.
|title=Effects of vitamin D and resveratrol on metabolic associated markers in liver and adipose tissue from SAMP8 mice.
|date=10.2020
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32717201
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28411010
|full-text-url=https://sci-hub.do/10.1016/j.imlet.2020.07.004
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.03.017
}}
}}
* {{medline-title
* {{medline-title
|title=A Comprehensive Evaluation of the Impact of Bovine Milk Containing Different Beta-Casein Profiles on Gut Health of Ageing Mice.
|title=Novel Senescent Regulatory T-Cell Subset with Impaired Suppressive Function in Rheumatoid Arthritis.
|date=19.07.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32707687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28373873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400800
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357868
}}
}}
* {{medline-title
* {{medline-title
|title=Premature aging of circulating T cells predicts all-cause mortality in hemodialysis patients.
|title=Long-term culture with lipopolysaccharide induces dose-dependent cytostatic and cytotoxic effects in THP-1 monocytes.
|date=13.07.2020
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32660510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28341289
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359274
|full-text-url=https://sci-hub.do/10.1016/j.tiv.2017.03.009
}}
}}
* {{medline-title
* {{medline-title
|title=In-depth immune cellular profiling reveals sex-specific associations with frailty.
|title=Arginase-II Promotes Tumor Necrosis Factor-α Release From Pancreatic Acinar Cells Causing β-Cell Apoptosis in Aging.
|date=2020
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32582361
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356309
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310472
|full-text-url=https://sci-hub.do/10.2337/db16-1190
}}
}}
* {{medline-title
* {{medline-title
|title=CD70 contributes to age-associated T cell defects and overwhelming inflammatory responses.
|title=Consumption of green tea epigallocatechin-3-gallate enhances systemic immune response, antioxidative capacity and HPA axis functions in aged male swiss albino mice.
|date=19.06.2020
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32559178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28341876
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343466
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9696-6
}}
}}
* {{medline-title
* {{medline-title
|title=Comparison of Overall and Comorbidity-Free Life Expectancy Between Insured Adults With and Without HIV Infection, 2000-2016.
|title=17beta-estradiol Attenuates [[TNF]]-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway.
|date=01.06.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32539152
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28255267
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296391
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332869
}}
}}
* {{medline-title
* {{medline-title
|title=Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model.
|title=Frailty and Circulating Markers of Inflammation in HIV  and HIV- Men in the Multicenter AIDS Cohort Study.
|date=11.06.2020
|date=01.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32545199
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28225718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365031
}}
}}
* {{medline-title
* {{medline-title
|title=Thymus aging in mice deficient in either EphB2 or EphB3, two master regulators of thymic epithelium development.
|title=Peripheral administration of the soluble [[TNF]] inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice.
|date=10.2020
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32506584
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28237313
|full-text-url=https://sci-hub.do/10.1002/dvdy.212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464789
}}
}}
* {{medline-title
* {{medline-title
|title=CD8  T-cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with PARN and DKC1 mutations.
|title=Interleukin-37 suppresses the inflammatory response to protect cardiac function in old endotoxemic mice.
|date=09.2020
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32452087
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28237874
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441934
}}
}}
* {{medline-title
* {{medline-title
|title=Short-Term Environmental Enrichment is a Stronger Modulator of Brain Glial Cells and Cervical Lymph Node T Cell Subtypes than Exercise or Combined Exercise and Enrichment.
|title=From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration.
|date=25.05.2020
|date=22.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32451728
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28185567
|full-text-url=https://sci-hub.do/10.1007/s10571-020-00862-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133493
}}
}}
* {{medline-title
* {{medline-title
|title=Viral and host factors related to the clinical outcome of COVID-19.
|title=High Volume Exercise Training in Older Athletes Influences Inflammatory and Redox Responses to Acute Exercise.
|date=07.2020
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434211
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28181836
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2355-0
|full-text-url=https://sci-hub.do/10.1123/japa.2016-0219
}}
}}
* {{medline-title
* {{medline-title
|title=Use of comedications and potential drug-drug interactions in people living with HIV in China.
|title=β -Microglobulin participates in development of lung emphysema by inducing lung epithelial cell senescence.
|date=07.2020
|date=01.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32354599
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|title=Polydatin attenuates d-galactose-induced liver and brain damage through its anti-oxidative, anti-inflammatory and anti-apoptotic effects in mice.
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|title=LTA1 is a safe, intranasal enterotoxin-based adjuvant that improves vaccine protection against influenza in young, old and B-cell-depleted (μMT) mice.
|title=Selenium attenuates apoptosis, inflammation and oxidative stress in the blood and brain of aged rats with scopolamine-induced dementia.
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|title=Metallothionein Prevents Age-Associated Cardiomyopathy via Inhibiting NF-κB Pathway Activation and Associated Nitrative Damage to 2-OGD.
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|title=Short Communication: Getting Older with HIV: Increasing Frequency of Comorbidities and Polypharmacy in Brazilian HIV Patients.
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|title=Gait Speed Decline Is Associated with Hemoglobin A1C, Neurocognitive Impairment, and Black Race in Persons with HIV.
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|title=Noncommunicable Diseases Burden and Risk Factors in a Cohort of HIV+ Elderly Patients in Malawi.
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|title=Aging promotes reorganization of the [[CD4]] T cell landscape toward extreme regulatory and effector phenotypes.
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|title=Blood amyloid-β protein isoforms are affected by HIV-1 in a subtype-dependent pattern.
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|title=Effects of aging, baseline renal function and stage of HIV infection on post-treatment changes in renal function among HIV-infected patients: a retrospective cohort study.
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|title=Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d'Ivoire: A model-based analysis.
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|title=Fibrillar Amyloid-β Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3×Tg-AD Transgenic Mouse.
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|title=Albumin, white blood cell count, and body mass index improve discrimination of mortality in HIV-positive individuals.
|title=Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence.
|date=01.04.2019
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30649058
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749990
|full-text-url=https://sci-hub.do/10.1016/j.plefa.2015.10.006
}}
}}
* {{medline-title
* {{medline-title
|title=The impact of senescence-associated T cells on immunosenescence and age-related disorders.
|title=[[TNF]] Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity.
|date=2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30603051
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26766566
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713203
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}}
* {{medline-title
* {{medline-title
|title=Post-thymic [[CD4]] positive cytotoxic T cell infiltrates of the skin: A clinical and histomorphologic spectrum of the unique [[CD4]] positive T cell of immunosenescence.
|title=Association of longevity with [[TNF]]-α G308A and IL-6 G174C polymorphic inflammatory biomarkers in Caucasians: a meta-analysis.
|date=02.2019
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30572149
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26754162
|full-text-url=https://sci-hub.do/10.1016/j.anndiagpath.2018.10.010
|full-text-url=https://sci-hub.do/10.1007/s00391-015-0992-y
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}}
* {{medline-title
* {{medline-title
|title=The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy.
|title=Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility.
|date=2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30560130
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26762510
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802783
}}
}}
* {{medline-title
* {{medline-title
|title=Immune Response-Dependent Assembly of IMP Dehydrogenase Filaments.
|title=Sirt6 regulates dendritic cell differentiation, maturation, and function.
|date=2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30555474
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26761436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761712
}}
}}
* {{medline-title
* {{medline-title
|title=Correlation of cell-surface CD8 levels with function, phenotype and transcriptome of naive CD8 T cells.
|title=Aging-dependent decline of IL-10 producing B cells coincides with production of antinuclear antibodies but not rheumatoid factors.
|date=04.2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30556901
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26721376
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418459
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.12.009
}}
}}
* {{medline-title
* {{medline-title
|title=The poly-omics of ageing through individual-based metabolic modelling.
|title=Kupffer cells-dependent inflammation in the injured liver increases recruitment of mesenchymal stem cells in aging mice.
|date=20.11.2018
|date=12.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453872
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26716516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245500
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811445
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro.
|title=Interaction of mouse splenocytes and macrophages with bacterial strains in vitro: the effect of age in the immune response.
|date=2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30408092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26689225
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224077
|full-text-url=https://sci-hub.do/10.3920/BM2015.0094
}}
}}
* {{medline-title
* {{medline-title
|title=Increased expression of PD1 and CD39 on CD3  [[CD4]]  skin T cells in the elderly.
|title=Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm.
|date=01.2019
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30431182
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26698666
|full-text-url=https://sci-hub.do/10.1111/exd.13842
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2015.12.012
}}
}}
* {{medline-title
* {{medline-title
|title=CD8 , but not [[CD4]] effector/memory T cells, express the [[[[CD4]]4]] [[CD4]]5RB  phenotype with aging, which displays reduced expression levels of P2X  receptor and ATP-induced cellular responses.
|title=Role of [[SHOX2]] in the development of intervertebral disc degeneration.
|date=03.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30383448
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26697824
|full-text-url=https://sci-hub.do/10.1096/fj.201800867R
|full-text-url=https://sci-hub.do/10.1002/jor.23140
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}}
* {{medline-title
* {{medline-title
|title=Heavy Alcohol Use and Age Effects on HIV-Associated Neurocognitive Function.
|title=Melatonin decreases the expression of inflammation and apoptosis markers in the lung of a senescence-accelerated mice model.
|date=01.2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30371953
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26656745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467512
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.11.021
}}
}}
* {{medline-title
* {{medline-title
|title=Thymic Epithelial Cell Support of Thymopoiesis Does Not Require [i]Klotho[/i].
|title=Age-related neuroinflammation and changes in AKT-GSK-3β and WNT/ β-CATENIN signaling in rat hippocampus.
|date=01.12.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373854
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26647069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275142
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712335
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of polysaccharides from a Korean ginseng berry on the immunosenescence of aged mice.
|title=Aging has small effects on initial ischemic acute kidney injury development despite changing intrarenal immunologic micromilieu in mice.
|date=10.2018
|date=15.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30337804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26661651
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187098
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00217.2015
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of HIV Infection, methamphetamine dependence and age on cortical thickness, area and volume.
|title=Inflammaging and Anti-Inflammaging: The Role of Cytokines in Extreme Longevity.
|date=2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30342393
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26658771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197439
|full-text-url=https://sci-hub.do/10.1007/s00005-015-0377-3
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of age, HIV, and HIV-associated clinical factors on neuropsychological functioning and brain regional volume in HIV+ patients on effective treatment.
|title=Effect of ZIP2 Gln/Arg/Leu (rs2234632) polymorphism on zinc homeostasis and inflammatory response following zinc supplementation.
|date=02.2019
|date=11-12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30298203
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26643924
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416454
|full-text-url=https://sci-hub.do/10.1002/biof.1247
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in the Structure and Cell Composition of Human Carinal Lymph Nodes during Aging.
|title=Ageing and the telomere connection: An intimate relationship with inflammation.
|date=09.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225704
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26616852
|full-text-url=https://sci-hub.do/10.1007/s10517-018-4246-z
|full-text-url=https://sci-hub.do/10.1016/j.arr.2015.11.006
}}
}}
* {{medline-title
* {{medline-title
|title=[[CD28]]  pro-atherogenic [[CD4]] T-cells explain the link between CMV infection and an increased risk of cardiovascular death.
|title=Responses of Dendritic Cells to TLR-4 Stimulation Are Maintained in the Elderly and Resist the Effects of CMV Infection Seen in the Young.
|date=2018
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30214635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26615178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134924
|full-text-url=https://sci-hub.do/10.1093/gerona/glv119
}}
}}
* {{medline-title
* {{medline-title
|title=Chromogenic Multiplex Immunohistochemistry Reveals Modulation of the Immune Microenvironment Associated with Survival in Elderly Patients with Lung Adenocarcinoma.
|title=Dietary supplementation with the polyphenol-rich açaí pulps (Euterpe oleracea Mart. and Euterpe precatoria Mart.) improves cognition in aged rats and attenuates inflammatory signaling in BV-2 microglial cells.
|date=13.09.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216999
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26618555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162494
|full-text-url=https://sci-hub.do/10.1080/1028415X.2015.1115213
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of caffeine and phosphodiesterase inhibitors on activation of neonatal T lymphocytes.
|title=Age and diabetes related changes of the retinal capillaries: An ultrastructural and immunohistochemical study.
|date=11.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30177027
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26604209
|full-text-url=https://sci-hub.do/10.1016/j.imbio.2018.07.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806738
}}
}}
* {{medline-title
* {{medline-title
|title=Alterations with age in peripheral blood lymphocyte subpopulations and cytokine synthesis in beagles.
|title=Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats.
|date=2012
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30101087
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26594596
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067671
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642830
}}
}}
* {{medline-title
* {{medline-title
|title=Some deterministic and stochastic mathematical models of naïve T-cell homeostasis.
|title=The relationship between inflammatory markers and voxel-based gray matter volumes in nondemented older adults.
|date=09.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30129198
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26559883
|full-text-url=https://sci-hub.do/10.1111/imr.12696
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.10.008
}}
}}
* {{medline-title
* {{medline-title
|title=An imbalance in the T-helper phenotypes displayed by senescent [[CD4]] [[CD28]]  T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus.
|title=Change in N-Glycosylation of Plasma Proteins in Japanese Semisupercentenarians.
|date=11.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111238
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26559536
|full-text-url=https://sci-hub.do/10.1177/0961203318793715
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641608
}}
}}
* {{medline-title
* {{medline-title
|title=The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging.
|title=Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.
|date=2018
|date=25.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26518879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066563
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692211
}}
}}
* {{medline-title
* {{medline-title
|title=Altered [[CD4]]  T cell immunity in nurses occupationally exposed to viral pathogens.
|title=Prognostic impact of circulating Her-2-reactive T-cells producing pro- and/or anti-inflammatory cytokines in elderly breast cancer patients.
|date=11.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30076783
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26500775
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617728
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}}
* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=Age differences in cytokine expression under conditions of health using experimental pain models.
|date=13.11.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26456458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664177
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}}
* {{medline-title
* {{medline-title
|title=HIV Persistence on Antiretroviral Therapy and Barriers to a Cure.
|title=CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections.
|date=2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26449262
|full-text-url=https://sci-hub.do/10.1007/978-981-13-0484-2_7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728314
}}
}}
* {{medline-title
* {{medline-title
|title=Inflammatory cytokines and immune system modulation by aerobic versus resisted exercise training for elderly.
|title=[Rich selenium-Banqiao-Codonopsis Pilosula mixture enhances immune function of aging mice].
|date=03.2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29977265
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26429536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016983
 
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}}
* {{medline-title
* {{medline-title
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|title=Estrogen upregulates inflammatory signals through NF-κB, IFN-γ, and nitric oxide via Akt/mTOR pathway in the lymph node lymphocytes of middle-aged female rats.
|date=05.07.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26440402
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2015.09.024
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}}
* {{medline-title
* {{medline-title
|title=Is Chronic Exposure to Low-Dose Organochlorine Pesticides a New Risk Factor of T-cell Immunosenescence?
|title=Influence of caffeine on 3,4-methylenedioxymethamphetamine-induced dopaminergic neuron degeneration and neuroinflammation is age-dependent.
|date=10.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991517
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26442661
|full-text-url=https://sci-hub.do/10.1158/1055-9965.EPI-17-0799
|full-text-url=https://sci-hub.do/10.1111/jnc.13377
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}}
* {{medline-title
* {{medline-title
|title=Humanized Mouse Model to Study Type 1 Diabetes.
|title=Associations of Circulating Soluble Tumor Necrosis Factor-α Receptors 1 and 2 with Interleukin-6 Levels in an Aging Cohort of Injection Drug Users with or at High Risk for HIV Infection.
|date=09.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967002
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26414536
|full-text-url=https://sci-hub.do/10.2337/db18-0202
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663639
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}}
* {{medline-title
* {{medline-title
|title=Long-term HIV/AIDS survivors: Patients living with HIV infection retained in care for over 20 years. What have we learned?
|title=Chronic inflammation and risk of colorectal and other obesity-related cancers: The health, aging and body composition study.
|date=11.2018
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29933720
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26413860
|full-text-url=https://sci-hub.do/10.1177/0956462418778705
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955608
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}}
* {{medline-title
* {{medline-title
|title=Older men display elevated levels of senescence-associated exercise-responsive [[CD28]]  angiogenic T cells compared with younger men.
|title=IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation.
|date=06.2018
|date=15.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29939490
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26373740
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016626
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572693
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}}
* {{medline-title
* {{medline-title
|title=Association of antiretroviral therapy with brain aging changes among HIV-infected adults.
|title=A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice.
|date=10.09.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29912063
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115290
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}}
* {{medline-title
* {{medline-title
|title=Changes in alcohol use associated with changes in HIV disease severity over time: A national longitudinal study in the Veterans Aging Cohort.
|title=Exacerbation of tumor necrosis factor-induced vascular leak syndrome by aging.
|date=01.08.2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29859388
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26349974
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344121
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2015.07.041
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}}
* {{medline-title
* {{medline-title
|title=Enhanced survival of BCG-stimulated dendritic cells: involvement of anti-apoptotic proteins and NF-κB.
|title=Skeletal muscle cells possess a 'memory' of acute early life [[TNF]]-α exposure: role of epigenetic adaptation.
|date=20.06.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29848490
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26349924
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031337
|full-text-url=https://sci-hub.do/10.1007/s10522-015-9604-x
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}}
* {{medline-title
* {{medline-title
|title=Abnormalities of age-related T cell senescence in Parkinson's disease.
|title=Migrational changes of mesenchymal stem cells in response to cytokines, growth factors, hypoxia, and aging.
|date=28.05.2018
|date=15.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29807534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26335540
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972443
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2015.08.019
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}}
* {{medline-title
* {{medline-title
|title=Oral Microbiome in HIV-Infected Women: Shifts in the Abundance of Pathogenic and Beneficial Bacteria Are Associated with Aging, HIV Load, [[CD4]] Count, and Antiretroviral Therapy.
|title=GADD34-deficient mice develop obesity, nonalcoholic fatty liver disease, hepatic carcinoma and insulin resistance.
|date=03.2019
|date=28.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808701
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26316333
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551985
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}}
* {{medline-title
* {{medline-title
|title=The parasite-derived rOv-ASP-1 is an effective antigen-sparing [[CD4]]  T cell-dependent adjuvant for the trivalent inactivated influenza vaccine, and functions in the absence of MyD88 pathway.
|title=Effects of 6-month supplementation with β-hydroxy-β-methylbutyrate, glutamine and arginine on vascular endothelial function of older adults.
|date=14.06.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29764680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26306566
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595497
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740211
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}}
* {{medline-title
* {{medline-title
|title=Vitamin D levels correlate with lymphocyte subsets in elderly patients with age-related diseases.
|title=Monocyte Phenotype and Polyfunctionality Are Associated With Elevated Soluble Inflammatory Markers, Cytomegalovirus Infection, and Functional and Cognitive Decline in Elderly Adults.
|date=16.05.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769621
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26286603
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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007736
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}}
* {{medline-title
* {{medline-title
|title=Age and [[CD4]] count are dominant factors in the prediction of anaemia in Javanese HIV patients.
|title=Age-related increased prevalence of asthma and nasal polyps in chronic rhinosinusitis and its association with altered IL-6 trans-signaling.
|date=2018
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}}
* {{medline-title
* {{medline-title
|title=Effects of Fish Oil on HIV-Related Inflammation and Markers of Immunosenescence: A Randomized Clinical Trial.
|title=Inflammatory Markers Change with Age, but do not Fall Beyond Reported Normal Ranges.
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}}
* {{medline-title
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|title=End-stage renal disease, dialysis, kidney transplantation and their impact on [[CD4]]  T-cell differentiation.
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* {{medline-title
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|title=Multivariate Analysis of Increase in Life Span of Caenorhabditis elegans Through Intestinal Colonization by Indigenous Probiotic Strains.
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}}
* {{medline-title
* {{medline-title
|title=Transcriptional Profiling of Age-Associated Gene Expression Changes in Human Circulatory CD1c+ Myeloid Dendritic Cell Subset.
|title=Senescent profile of angiogenic T cells from systemic lupus erythematosus patients.
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}}
* {{medline-title
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|title=Impact of Aging on the Frequency, Phenotype, and Function of CD161-Expressing T Cells.
|title=Effects of home-based bench step exercise on inflammatory cytokines and lipid profiles in elderly Japanese females: A randomized controlled trial.
|date=2018
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}}
* {{medline-title
* {{medline-title
|title=Hyper-Expression of PD-1 Is Associated with the Levels of Exhausted and Dysfunctional Phenotypes of Circulating CD161 TCR iVα7.2  Mucosal-Associated Invariant T Cells in Chronic Hepatitis B Virus Infection.
|title=Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age.
|date=2018
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}}
* {{medline-title
* {{medline-title
|title=The impact of aging on [[CD4]]  T cell responses to influenza infection.
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|title=Differences Between Pediatric and Adult T Cell Responses to [i]In Vitro[/i] Staphylococcal Enterotoxin B Stimulation.
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|title=Time-restricted feeding influences immune responses without compromising muscle performance in older men.
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* {{medline-title
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|title=C-Reactive Protein Impairs Dendritic Cell Development, Maturation, and Function: Implications for Peripheral Tolerance.
|title=LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING.
|date=2018
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29556231
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}}
* {{medline-title
* {{medline-title
|title=Senescent T-Cells Promote Bone Loss in Rheumatoid Arthritis.
|title=Age-Dependent Alterations in the Interactions of NF-κB and N-myc with GLT-1/EAAT2 Promoter in the Pericontusional Cortex of Mice Subjected to Traumatic Brain Injury.
|date=2018
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}}
* {{medline-title
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|title=Inclusion body myositis and human immunodeficiency virus type 1: A new case report and literature review.
|title=The Werner Protein Acts as a Coactivator of Nuclear Factor κB (NF-κB) on HIV-1 and Interleukin-8 (IL-8) Promoters.
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}}
* {{medline-title
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|title=Possible correlation between gut microbiota and immunity among healthy middle-aged and elderly people in southwest China.
|title=Interleukin-6 as a first-rated serum inflammatory marker to predict mortality and hospitalization in the oldest old: A regression and CART approach in the BELFRAIL study.
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}}
* {{medline-title
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|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers.
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|date=05.2018
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}}
* {{medline-title
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}}
* {{medline-title
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|title=Age-Dependent Pre-Vaccination Immunity Affects the Immunogenicity of Varicella Zoster Vaccination in Middle-aged Adults.
|title=Increased serum levels of eotaxin/CCL11 in late-stage patients with bipolar disorder: An accelerated aging biomarker?
|date=2018
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|full-text-url=https://sci-hub.do/10.1016/j.jad.2014.12.010
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* {{medline-title
* {{medline-title
|title=Dynamics of [[CD4]] and CD8 T-Cell Subsets and Inflammatory Biomarkers during Early and Chronic HIV Infection in Mozambican Adults.
|title=Vascular endothelial function is improved by oral glycine treatment in aged rats.
|date=2017
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}}
* {{medline-title
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|title=Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota.
|title=Inhibition of hedgehog signalling attenuates UVB-induced skin photoageing.
|date=04.01.2018
|date=08.2015
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}}
* {{medline-title
* {{medline-title
|title=Signal transduction changes in [[CD4]]  and CD8  T cell subpopulations with aging.
|title=Age-associated modifications of intestinal permeability and innate immunity in human small intestine.
|date=05.2018
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|full-text-url=https://sci-hub.do/10.1042/CS20150046
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}}
* {{medline-title
* {{medline-title
|title=Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges.
|title=The stimulatory effect of the [[TLR4]]-mediated adjuvant glucopyranosyl lipid A is well preserved in old age.
|date=16.01.2018
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}}
* {{medline-title
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|title=Age-associated alteration in Th17 cell response is related to endothelial cell senescence and atherosclerotic cerebral infarction.
|title=Inhibiting tumor necrosis factor-α signaling attenuates postoperative cognitive dysfunction in aged rats.
|date=2017
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* {{medline-title
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|title=Lower resting and exercise-induced circulating angiogenic progenitors and angiogenic T cells in older men.
|title=Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by high-fat/high-sucrose feeding at middle age.
|date=01.03.2018
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|title=[Molecular mechanisms of combined extremely radiofrequency and infrared therapy in various age patients with chronic parodontitis].
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}}
* {{medline-title
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|title=Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase-induced inflammation.
|title=Exercise training increases anabolic and attenuates catabolic and apoptotic processes in aged skeletal muscle of male rats.
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|title=Transient early food restriction leads to hypothalamic changes in the long-lived crowded litter female mice.
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}}
* {{medline-title
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|title=HIV and Age Do Not Synergistically Affect Age-Related T-Cell Markers.
|title=The probiotic mixture IRT5 ameliorates age-dependent colitis in rats.
|date=01.03.2018
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|full-text-url=https://sci-hub.do/10.1016/j.intimp.2015.04.021
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* {{medline-title
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|title=Differential Relationships among Circulating Inflammatory and Immune Activation Biomediators and Impact of Aging and Human Immunodeficiency Virus Infection in a Cohort of Injection Drug Users.
|title=Essential role of [[POLDIP2]] in Tau aggregation and neurotoxicity via autophagy/proteasome inhibition.
|date=2017
|date=26.06.2015
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|title=T Follicular Helper Cells and B Cell Dysfunction in Aging and HIV-1 Infection.
|title=Inflammaging decreases adaptive and innate immune responses in mice and humans.
|date=2017
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|title=Attachment and telomere length: more evidence for psychobiological connections between close relationships, health, and aging.
|title=Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli.
|date=06.2018
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}}
* {{medline-title
* {{medline-title
|title=A Pharmacist-Led Program to Evaluate and Reduce Polypharmacy and Potentially Inappropriate Prescribing in Older HIV-Positive Patients.
|title=Relationship between biomarkers of inflammation, oxidative stress and endothelial/microcirculatory function in successful aging versus healthy youth: a transversal study.
|date=12.2017
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|title=Associations between immunological function and memory recall in healthy adults.
|title=No strong correlations between serum cytokine levels, CMV serostatus and hand-grip strength in older subjects in the Berlin BASE-II cohort.
|date=12.2017
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|full-text-url=https://sci-hub.do/10.1016/j.bandc.2017.10.002
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|title=Reevaluation of immune activation in the era of cART and an aging HIV-infected population.
|title=Fibroblast growth factor 21 protects mouse brain against D-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation.
|date=19.10.2017
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|title=Cancer-Attributable Mortality Among People With Treated Human Immunodeficiency Virus Infection in North America.
|title=The p53/miR-17/Smurf1 pathway mediates skeletal deformities in an age-related model via inhibiting the function of mesenchymal stem cells.
|date=15.08.2017
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29017269
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}}
* {{medline-title
* {{medline-title
|title=Inhibition of telomerase activity and induction of apoptosis by Rhodospirillum rubrum L-asparaginase in cancer Jurkat cell line and normal human [[CD4]]+ T lymphocytes.
|title=Acute exercise increases hippocampal [[TNF]]-α, Caspase-3 and Caspase-7 expression in healthy young and older mice.
|date=11.2017
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28984046
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* {{medline-title
* {{medline-title
|title=Predictors of transitions in frailty severity and mortality among people aging with HIV.
|title=Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses.
|date=2017
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28981535
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* {{medline-title
|title=High prevalence of "non-dipping" blood pressure and vascular stiffness in HIV-infected South Africans on antiretrovirals.
|title=Autophagy in axonal degeneration in glaucomatous optic neuropathy.
|date=2017
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28931072
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25816798
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|full-text-url=https://sci-hub.do/10.1016/j.preteyeres.2015.03.002
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* {{medline-title
* {{medline-title
|title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses.
|title=Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal [[TLR4]] activation in aged rats.
|date=17.08.2017
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25839444
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2015.02.008
}}
}}
==SIRT1==
* {{medline-title
* {{medline-title
|title=Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats.
|title=Influences of age and sex on leukocytes of healthy horses and their ex vivo cytokine release.
|date=03.12.2020
|date=15.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274583
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782350
|full-text-url=https://sci-hub.do/10.1111/acel.13279
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2015.02.011
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective.
|title=Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture.
|date=05.12.2020
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33280374
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25797136
|full-text-url=https://sci-hub.do/10.1021/acschemneuro.0c00696
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.03.009
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells.
|title=Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment.
|date=10.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33149857
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25784952
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585532
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362825
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT1]] Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence.
|title=Association of systemic inflammation with epicardial fat and coronary artery calcification.
|date=04.11.2020
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33158256
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25763815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694272
|full-text-url=https://sci-hub.do/10.1007/s00011-015-0809-x
}}
}}
* {{medline-title
* {{medline-title
|title=Histone Deacetylase [[SIRT1]], Smooth Muscle Cell Function, and Vascular Diseases.
|title=Age-associated changes in granulosa cell transcript abundance in equine preovulatory follicles.
|date=2020
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25775380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573826
|full-text-url=https://sci-hub.do/10.1071/RD14467
}}
}}
* {{medline-title
* {{medline-title
|title=6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing [[SIRT1]] and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation.
|title=Effects of er-miao-san extracts on [[TNF]]-alpha-induced MMP-1 expression in human dermal fibroblasts.
|date=27.10.2020
|date=26.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33111210
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761492
|full-text-url=https://sci-hub.do/10.1007/s11010-020-03951-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417304
}}
}}
* {{medline-title
* {{medline-title
|title=Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through [[SIRT1]] activation and AKT/mTOR pathway inhibition.
|title=Immunostimulatory effects of [[RACK1]] pseudosubstrate in human leukocytes obtained from young and old donors.
|date=30.09.2020
|date=30.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010892
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25779661
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.09.096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466631
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT1]] Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence.
|title=Patient-relevant endpoints in inflammatory bowel diseases--have changes occurred in Germany over the past twelve years?
|date=2020
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25740812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508177
|full-text-url=https://sci-hub.do/10.1093/ecco-jcc/jjv041
}}
}}
* {{medline-title
* {{medline-title
|title=The Role of Sirtuins in Kidney Diseases.
|title=Anti-inflammatory effect of resveratrol in old mice liver.
|date=12.09.2020
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932720
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25687021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555196
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.02.004
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men.
|title=Blockade of PD-1 or p38 MAP kinase signaling enhances senescent human CD8( ) T-cell proliferation by distinct pathways.
|date=11.2020
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32919015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25707450
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111090
|full-text-url=https://sci-hub.do/10.1002/eji.201445312
}}
}}
* {{medline-title
* {{medline-title
|title=Virus-Induced Asthma Exacerbations: [[SIRT1]] Targeted Approach.
|title=Circulating [[TNF]] and mitochondrial DNA are major determinants of neutrophil phenotype in the advanced-age, frail elderly.
|date=13.08.2020
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32823491
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25660689
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464235
|full-text-url=https://sci-hub.do/10.1016/j.molimm.2015.01.015
}}
}}
* {{medline-title
* {{medline-title
|title=Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts.
|title=Salidroside protects against premature senescence induced by ultraviolet B irradiation in human dermal fibroblasts.
|date=12.2020
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793997
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25639473
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09896-6
|full-text-url=https://sci-hub.do/10.1111/ics.12202
}}
* {{medline-title
|title=Selected pro- and anti-inflammatory cytokines in cerebrospinal fluid in normal pressure hydrocephalus.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25617881
 
}}
}}
* {{medline-title
* {{medline-title
|title=Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/[[SIRT1]]-FOXA3-Beclin1 pathway.
|title=Vaginal cytokines do not correlate with postmenopausal vulvovaginal symptoms.
|date=01.10.2020
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25559048
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111053
|full-text-url=https://sci-hub.do/10.3109/09513590.2014.995080
}}
}}
* {{medline-title
* {{medline-title
|title=Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence.
|title=Age-related differences in polyfunctional T cell responses.
|date=08.2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32722945
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25512758
|full-text-url=https://sci-hub.do/10.1080/15412555.2020.1797657
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265991
}}
}}
* {{medline-title
* {{medline-title
|title=Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of [[SIRT1]] in Human Dermal Fibroblasts.
|title=Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of D-galactose treated mice.
|date=01.07.2020
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32404543
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25504333
|full-text-url=https://sci-hub.do/10.1248/bpb.b20-00094
|full-text-url=https://sci-hub.do/10.1039/c4fo00862f
}}
}}
* {{medline-title
* {{medline-title
|title=SRT1720-induced activation of [[SIRT1]] alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485.
|title=Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice.
|date=07.2020
|date=05.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32421926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25460022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327920
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2014.11.017
}}
}}
* {{medline-title
* {{medline-title
|title=miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss.
|title=Tumor necrosis factor-α-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo.
|date=2020
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32292498
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25457675
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150474
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300401
}}
}}
* {{medline-title
* {{medline-title
|title=Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes.
|title=Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice.
|date=01-12.2020
|date=15.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270742
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25377884
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153179
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297777
}}
}}
* {{medline-title
* {{medline-title
|title=Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats.
|title=Pre-Operative, High-IL-6 Blood Level is a Risk Factor of Post-Operative Delirium Onset in Old Patients.
|date=10.2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32249404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25368603
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09875-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201145
}}
}}
* {{medline-title
* {{medline-title
|title=The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis.
|title=Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease.
|date=2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32214805
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25341516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084123
|full-text-url=https://sci-hub.do/10.1159/000364934
}}
}}
* {{medline-title
* {{medline-title
|title=Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells.
|title=Inflammasomes in neuroinflammation and changes in brain function: a focused review.
|date=2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158519
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25339862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188030
}}
}}
* {{medline-title
* {{medline-title
|title=Spatiotemporal gating of [[SIRT1]] functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia.
|title=Impact of gasless laparoscopy on circulation, respiration, stress response, and other complications in gynecological geriatrics.
|date=24.03.2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32152092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25356152
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104039
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211802
}}
}}
* {{medline-title
* {{medline-title
|title=Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of [[SIRT1]].
|title=Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice.
|date=2020
|date=17.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32132865
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25366964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235633
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT1]] and aging related signaling pathways.
|title=Sleep deprivation and divergent toll-like receptor-4 activation of cellular inflammation in aging.
|date=04.2020
|date=01.02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32084459
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25325509
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111215
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288601
}}
}}
* {{medline-title
* {{medline-title
|title=Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of [[SIRT1]] signaling.
|title=Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging.
|date=01.05.2020
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32088214
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25324219
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117452
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612381
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of [[SIRT1]] activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects.
|title=The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice.
|date=04.2020
|date=15.12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25326534
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206476
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269699
}}
}}
* {{medline-title
* {{medline-title
|title=Deacetylation of MRTF-A by [[SIRT1]] defies senescence induced down-regulation of collagen type I in fibroblast cells.
|title=Evidence for altered inflammatory and repair responses in symptomatic carotid plaques from elderly patients.
|date=01.05.2020
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061777
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25240113
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165723
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2014.08.042
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal [[SIRT1]] Levels Improving Cognition in Aged Rats.
|title=Immunosenescence in monocytes, macrophages, and dendritic cells: lessons learned from the lung and heart.
|date=26.01.2020
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31991916
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25251662
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071257
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256137
}}
}}
* {{medline-title
* {{medline-title
|title=Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating [[SIRT1]].
|title=Ferrocifen derivatives that induce senescence in cancer cells: selected examples.
|date=01.2020
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970335
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25261808
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957441
|full-text-url=https://sci-hub.do/10.1016/j.jinorgbio.2014.08.015
}}
}}
* {{medline-title
* {{medline-title
|title=Two novel [[SIRT1]] activators, SCIC2 and SCIC2.1, enhance [[SIRT1]]-mediated effects in stress response and senescence.
|title=Role of mitochondrial reactive oxygen species in age-related inflammatory activation of endothelium.
|date=06-07.2020
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31942817
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25239871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169860
}}
}}
* {{medline-title
* {{medline-title
|title=Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
|title=Aging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery.
|date=23.12.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31881011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25198176
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949053
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157839
}}
}}
* {{medline-title
* {{medline-title
|title=The protective role of omentin-1 in IL-1β-induced chondrocyte senescence.
|title=Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson's disease by laser ablation inductively coupled plasma mass spectrometry.
|date=12.2020
|date=20.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31852248
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25142911
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1699803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156608
}}
}}
* {{medline-title
* {{medline-title
|title=The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD  Level Is Lower than the Sirtuin-Saturating Concentrations.
|title=Interleukin-1 deficiency prolongs ovarian lifespan in mice.
|date=24.12.2019
|date=26.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31878234
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25114230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982340
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151745
}}
}}
* {{medline-title
* {{medline-title
|title=Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells.
|title=HIV-1 transgenic rats display alterations in immunophenotype and cellular responses associated with aging.
|date=06.2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792920
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25127062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134284
}}
}}
* {{medline-title
* {{medline-title
|title=Central nervous system [[SIRT1]] expression is required for cued and contextual fear conditioning memory responses in aging mice.
|title=Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers.
|date=23.09.2019
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31763496
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25104822
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839599
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296167
}}
* {{medline-title
|title=Relationship between vitamin D and inflammatory markers in older individuals.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25086618
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150893
}}
}}
* {{medline-title
* {{medline-title
|title=Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education.
|title=Association of pulse pressure with serum [[TNF]]-α and neutrophil count in the elderly.
|date=10.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31785216
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25105150
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066939
}}
}}
* {{medline-title
* {{medline-title
|title=CO ameliorates endothelial senescence induced by 5-fluorouracil through [[SIRT1]] activation.
|title=Peritoneal exudate cells from long-lived rats exhibit increased IL-10/IL-1β expression ratio and preserved NO/urea ratio following LPS-stimulation in vitro.
|date=30.11.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704100
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25081109
|full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150890
}}
}}
* {{medline-title
* {{medline-title
|title=Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating [[SIRT1]] expression.
|title=Cortisol, cytokines, and hippocampal volume interactions in the elderly.
|date=20.10.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31631065
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25071562
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079951
}}
}}
* {{medline-title
* {{medline-title
|title=The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging.
|title=DaoTan decoction (DTD) inhibits tumor necrosis factor-α ([[TNF]]-α)-induced expression of intercellular adhesion molecule-1 (ICAM-1), p53 and p21, in human umbilical vein endothelia cells (HUVECs).
|date=2019
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31572218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25026345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751260
|full-text-url=https://sci-hub.do/10.3109/13880209.2014.891141
}}
}}
* {{medline-title
* {{medline-title
|title=Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer.
|title=Improvement in Th1/Th2 immune homeostasis, antioxidative status and resistance to pathogenic E. coli on consumption of probiotic Lactobacillus rhamnosus fermented milk in aging mice.
|date=03.2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544977
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25037247
|full-text-url=https://sci-hub.do/10.1002/jcp.29182
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150900
}}
}}
* {{medline-title
* {{medline-title
|title=Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure.
|title=Aging oppositely affects [[TNF]]-α and IL-10 production by macrophages from different rat strains.
|date=13.02.2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25009084
|full-text-url=https://sci-hub.do/10.1093/sleep/zsz217
|full-text-url=https://sci-hub.do/10.1007/s10522-014-9513-4
}}
}}
* {{medline-title
* {{medline-title
|title=Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of [[SIRT1]].
|title=Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging.
|date=2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24979747
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076296
}}
}}
* {{medline-title
* {{medline-title
|title=Activation of the miR-34a-Mediated [[SIRT1]]/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice.
|title=iPLA2β knockout mouse, a genetic model for progressive human motor disorders, develops age-related neuropathology.
|date=10.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31420820
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24919816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364003
}}
}}
* {{medline-title
* {{medline-title
|title=[Ginsenoside Rg_1 induces leukemia stem cell senescence via [[SIRT1]]/TSC_2 signal axis].
|title=Site-specific changes in cytokine response to septic dose of lipopolysaccharide in ovariectomized female rats.
|date=06.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31359662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24923901
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20190218.002
|full-text-url=https://sci-hub.do/10.1007/s40618-014-0094-5
}}
}}
* {{medline-title
* {{medline-title
|title=miR-23b-3p regulates apoptosis and autophagy via suppressing [[SIRT1]] in lens epithelial cells.
|title=D-galactose induced inflammation lipid peroxidation and platelet activation in rats.
|date=12.2019
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31338869
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24907931
|full-text-url=https://sci-hub.do/10.1002/jcb.29270
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2014.05.006
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity.
|title=Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity.
|date=10.2019
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24886741
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639009
}}
}}
* {{medline-title
* {{medline-title
|title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity.
|title=Bacteria and Toll-like receptor and cytokine mRNA expression profiles associated with canine arthritis.
|date=08.2019
|date=15.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24856731
|full-text-url=https://sci-hub.do/10.1089/cell.2019.0010
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2014.04.004
}}
}}
* {{medline-title
* {{medline-title
|title=Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence.
|title=Distinct age-matched serum biomarker profiles in patients with cutaneous T-cell lymphoma.
|date=01.10.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31265875
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24862743
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159039
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125529
}}
}}
* {{medline-title
* {{medline-title
|title=Involvement of [i]microRNA-34a[/i] in Age-Related Susceptibility to Oxidative Stress in ARPE-19 Cells by Targeting the Silent Mating Type Information Regulation 2 Homolog 1/p66shc Pathway: Implications for Age-Related Macular Degeneration.
|title=Age-related activation of MKK/p38/NF-κB signaling pathway in lung: from mouse to human.
|date=2019
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31249522
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24802989
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584679
|full-text-url=https://sci-hub.do/10.1016/j.exger.2014.04.017
}}
}}
* {{medline-title
* {{medline-title
|title=[[GPR39]] agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence.
|title=Changes in the expression of the Toll-like receptor system in the aging rat kidneys.
|date=12.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237151
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810370
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1626405
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014502
}}
}}
* {{medline-title
* {{medline-title
|title=Rational design of novel sirtuin 1 activators via structure-activity insights from application of QSAR modeling.
|title=Comparative analysis of low-level laser therapy (660 nm) on inflammatory biomarker expression during the skin wound-repair process in young and aged rats.
|date=2019
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31217784
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24801057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558509
|full-text-url=https://sci-hub.do/10.1007/s10103-014-1582-8
}}
}}
* {{medline-title
* {{medline-title
|title=Metformin prevents murine ovarian aging.
|title=Inflammation and prolonged QT time: results from the Cardiovascular Disease, Living and Ageing in Halle (CARLA) study.
|date=10.06.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182682
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24770373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000193
}}
}}
* {{medline-title
* {{medline-title
|title=Time-restricted feeding delays the emergence of the age-associated, neoplastic-prone tissue landscape.
|title=Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state.
|date=12.06.2019
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188781
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24759206
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205198
}}
}}
* {{medline-title
* {{medline-title
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|title=Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals.
|date=10.06.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24779584
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326942
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT1]] protects cochlear hair cell and delays age-related hearing loss via autophagy.
|title=Maturation of innate responses to mycobacteria over the first nine months of life.
|date=08.2019
|date=15.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24733845
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.04.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048703
}}
}}
* {{medline-title
* {{medline-title
|title=Transcriptome analysis revealed potential mechanisms of differences in physiological stress responses between caged male and female magpies.
|title=Effects of age and macrophage lineage on intracellular survival and cytokine induction after infection with Rhodococcus equi.
|date=03.06.2019
|date=15.07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31159743
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24736188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547487
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2014.03.010
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.
|title=IL-2/[[CD40]]-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice.
|date=10.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31144244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24744051
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082580
}}
* {{medline-title
|title=A comparison of pro-inflammatory cytokine mRNA expression in equine bronchoalveolar lavage (BAL) and peripheral blood.
|date=15.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24603016
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2014.02.001
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models.
|title=Moderate swimming exercise and caffeine supplementation reduce the levels of inflammatory cytokines without causing oxidative stress in tissues of middle-aged rats.
|date=02.2019
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31132911
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24481487
|full-text-url=https://sci-hub.do/10.1080/10799893.2019.1605529
|full-text-url=https://sci-hub.do/10.1007/s00726-014-1679-1
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular and Cellular Characterization of [[SIRT1]] Allosteric Activators.
|title=Effects of aging on influenza virus infection dynamics.
|date=2019
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31087296
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993746
}}
}}
* {{medline-title
* {{medline-title
|title=Total flavonoids from the Carya cathayensis Sarg. leaves inhibit HUVEC senescence through the miR-34a/[[SIRT1]] pathway.
|title=Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for "inflamm-aging".
|date=10.2019
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31106472
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24470107
|full-text-url=https://sci-hub.do/10.1002/jcb.28986
|full-text-url=https://sci-hub.do/10.1002/eji.201343921
}}
}}
* {{medline-title
* {{medline-title
|title=Impaired [[SIRT1]] activity leads to diminution in glomerular endowment without accelerating age-associated GFR decline.
|title=Markers of low-grade inflammation and endothelial dysfunction are related to reduced information processing speed and executive functioning in an older population - the Hoorn Study.
|date=05.2019
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31087539
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24485482
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513772
|full-text-url=https://sci-hub.do/10.1016/j.psyneuen.2013.11.011
}}
}}
* {{medline-title
* {{medline-title
|title=Estrogen-[[SIRT1]] Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis.
|title=Bacopa monnieri (L.) exerts anti-inflammatory effects on cells of the innate immune system in vitro.
|date=01.01.2020
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31105126
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24452710
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976724
|full-text-url=https://sci-hub.do/10.1039/c3fo60467e
}}
}}
* {{medline-title
* {{medline-title
|title=Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri.
|title=Resveratrol increases antioxidant defenses and decreases proinflammatory cytokines in hippocampal astrocyte cultures from newborn, adult and aged Wistar rats.
|date=09.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075496
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462605
|full-text-url=https://sci-hub.do/10.1016/j.gep.2019.05.001
|full-text-url=https://sci-hub.do/10.1016/j.tiv.2014.01.006
}}
}}
* {{medline-title
* {{medline-title
|title=Protective effect of vildagliptin on [[TNF]]-α-induced chondrocyte senescence.
|title=High [[TNF]]-α levels in resting B cells negatively correlate with their response.
|date=07.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24440385
|full-text-url=https://sci-hub.do/10.1002/iub.2049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989457
}}
}}
* {{medline-title
* {{medline-title
|title=Polymorphism rs7895833 in the [[SIRT1]] gene and its association with dyslipidaemia in the elderly.
|title=Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life.
|date=07-08.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31040057
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24370373
|full-text-url=https://sci-hub.do/10.1016/j.regg.2019.01.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003347
}}
}}
==APOE==
* {{medline-title
* {{medline-title
|title=Modulation of miR-34a/[[SIRT1]] signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis.
|title=Polygenic risk score of longevity predicts longer survival across an age-continuum.
|date=07.2019
|date=20.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026620
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33216869
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.03.013
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa289
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the [[SIRT1]] pathway in aged bone marrow.
|title=Association Between [[APOE]] Alleles and Change of Neuropsychological Tests in the Long Life Family Study.
|date=18.04.2019
|date=17.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31000692
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33216038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472410
|full-text-url=https://sci-hub.do/10.3233/JAD-201113
}}
}}
* {{medline-title
* {{medline-title
|title=Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom [i]Cordyceps militaris[/i] Linn., Ameliorates Age-Related Testicular Dysfunction in Rats.
|title=The [[APOE]] gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans.
|date=23.04.2019
|date=20.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31018574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33215813
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520895
|full-text-url=https://sci-hub.do/10.1002/alz.12230
}}
}}
* {{medline-title
* {{medline-title
|title=The resistant effect of [[SIRT1]] in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway.
|title=Homozygosity in the [i][[APOE]][/i] 3 Polymorphism Is Associated With Less Depression and Higher Serum Low-Density Lipoprotein in Chinese Elderly Schizophrenics.
|date=31.05.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30967498
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33178131
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509061
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593819
}}
}}
* {{medline-title
* {{medline-title
|title=Photobiomodulation and Coenzyme Q  Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice.
|title=Effect of apolipoprotein E polymorphism on cognition and brain in the Cambridge Centre for Ageing and Neuroscience cohort.
|date=2019
|date=01-12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33088920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545750
}}
}}
* {{medline-title
* {{medline-title
|title=The role of [[SIRT1]] in neuroinflammation and cognitive dysfunction in aged rats after anesthesia and surgery.
|title=Cardiovascular risk factors and [[APOE]]-ε4 status affect memory functioning in aging via changes to temporal stem diffusion.
|date=2019
|date=18.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30972182
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33070365
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456566
|full-text-url=https://sci-hub.do/10.1002/jnr.24734
}}
}}
* {{medline-title
* {{medline-title
|title=NAD  supplementation rejuvenates aged gut adult stem cells.
|title=[[APOE]] [i]ε[/i]4 and resting-state functional connectivity in racially/ethnically diverse older adults.
|date=06.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30917412
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32999914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508460
}}
}}
* {{medline-title
* {{medline-title
|title=[[NMNAT2]]-mediated NAD  generation is essential for quality control of aged oocytes.
|title=Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study.
|date=06.2019
|date=13.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909324
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32886741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662159
}}
}}
* {{medline-title
* {{medline-title
|title=Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure.
|title=When Culture Influences Genes: Positive Age Beliefs Amplify the Cognitive-Aging Benefit of [[APOE]] ε2.
|date=07.2019
|date=14.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30889315
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32835364
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489069
}}
}}
* {{medline-title
* {{medline-title
|title=Drugs targeting [[SIRT1]], a new generation of therapeutics for osteoporosis and other bone related disorders?
|title=Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study.
|date=05.2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862606
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32817639
|full-text-url=https://sci-hub.do/10.1016/j.phrs.2019.03.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446786
}}
}}
* {{medline-title
* {{medline-title
|title=Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks.
|title=Estimating the potential for dementia prevention through modifiable risk factors elimination in the real-world setting: a population-based study.
|date=11.03.2019
|date=07.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862067
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32767997
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414752
}}
}}
* {{medline-title
* {{medline-title
|title=Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions.
|title=Machine learning-based estimation of cognitive performance using regional brain MRI markers: the Northern Manhattan Study.
|date=04.2019
|date=01.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30794349
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32740887
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413655
|full-text-url=https://sci-hub.do/10.1007/s11682-020-00325-3
}}
}}
* {{medline-title
* {{medline-title
|title=Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson's disease.
|title=Effects of an [[APOE]] Promoter Polymorphism on Fronto-Parietal Functional Connectivity During Nondemented Aging.
|date=04.02.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30718471
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32694990
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338603
}}
}}
* {{medline-title
* {{medline-title
|title=Bone Marrow Mesenchymal Stem Cells-Derived Exosomal MiR-29b-3p Regulates Aging-Associated Insulin Resistance.
|title=The relationship of parental longevity with the aging brain-results from UK Biobank.
|date=26.02.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30715852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32671621
|full-text-url=https://sci-hub.do/10.1021/acsnano.8b09375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525531
}}
}}
* {{medline-title
* {{medline-title
|title=Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats.
|title=Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation.
|date=02.2019
|date=30.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712161
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32610143
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00663-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422733
}}
}}
* {{medline-title
* {{medline-title
|title=Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease.
|title=Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease.
|date=05.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32474467
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369125
}}
}}
* {{medline-title
* {{medline-title
|title=Generation of a novel model of primary human cell senescence through Tenovin-6 mediated inhibition of sirtuins.
|title=Effects of sex, age, and apolipoprotein E genotype on hippocampal parenchymal fraction in cognitively normal older adults.
|date=06.2019
|date=30.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666570
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32416384
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535423
|full-text-url=https://sci-hub.do/10.1016/j.pscychresns.2020.111107
}}
}}
* {{medline-title
* {{medline-title
|title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke.
|title=Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO).
|date=04.2019
|date=05.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32380778
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279440
}}
}}
* {{medline-title
* {{medline-title
|title=Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism.
|title=Apolipoprotein E and Health in Older Men: The Concord Health and Ageing in Men Project.
|date=23.01.2019
|date=25.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673631
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32342099
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366955
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa105
}}
}}
* {{medline-title
* {{medline-title
|title=Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation.
|title=CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease.
|date=2018
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622668
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32305782
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304815
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.03.008
}}
}}
* {{medline-title
* {{medline-title
|title=NKT-like cells reveal higher than T lymphocytes expression of cellular protective proteins HSP70 and [[SOD2]] and comparably increased expression of [[SIRT1]] in the oldest seniors.
|title=Association of Cardiovascular Risk Factors with Cerebral Perfusion in Whites and African Americans.
|date=2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30633320
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32310160
|full-text-url=https://sci-hub.do/10.5603/FHC.a2018.0025
|full-text-url=https://sci-hub.do/10.3233/JAD-190360
}}
}}
* {{medline-title
* {{medline-title
|title=Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway.
|title=Alzheimer's Risk Factors Age, [[APOE]] Genotype, and Sex Drive Distinct Molecular Pathways.
|date=04.2019
|date=03.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30597622
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32199103
|full-text-url=https://sci-hub.do/10.1111/jpi.12550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388065
}}
}}
* {{medline-title
* {{medline-title
|title=Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats.
|title=Less agreeable, better preserved? A PET amyloid and MRI study in a community-based cohort.
|date=23.12.2018
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30582744
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32169357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326662
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.02.004
}}
}}
* {{medline-title
* {{medline-title
|title=Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation.
|title=Physical Activity as Moderator of the Association Between [[APOE]] and Cognitive Decline in Older Adults: Results from Three Longitudinal Cohort Studies.
|date=2018
|date=25.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537739
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32110803
|full-text-url=https://sci-hub.do/10.1159/000495895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518558
}}
}}
* {{medline-title
* {{medline-title
|title=Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice.
|title=Longitudinal Maintenance of Cognitive Health in Centenarians in the 100-plus Study.
|date=15.04.2019
|date=05.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530184
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32101309
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.11.139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137688
}}
}}
* {{medline-title
* {{medline-title
|title=CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins [[SIRT1]], HSP70 and [[SOD2]].
|title=Interaction of [[APOE]], cerebral blood flow, and cortical thickness in the entorhinal cortex predicts memory decline.
|date=2018
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534181
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32048144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262966
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165062
}}
}}
* {{medline-title
* {{medline-title
|title=Amentoflavone Induces Autophagy and Modulates p53.
|title=Determinants of mesial temporal lobe volume loss in older individuals with preserved cognition: a longitudinal PET amyloid study.
|date=04.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30507085
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32057528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275431
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.12.002
}}
}}
* {{medline-title
* {{medline-title
|title=Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells.
|title=Long-term exposure to ambient air pollution, [[APOE]]-ε4 status, and cognitive decline in a cohort of older adults in northern Manhattan.
|date=03.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30476532
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31926436
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7024003
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuins: Developing Innovative Treatments for Aged-Related Memory Loss and Alzheimer's Disease.
|title=Evidence in support of chromosomal sex influencing plasma based metabolome vs [[APOE]] genotype influencing brain metabolome profile in humanized [[APOE]] male and female mice.
|date=2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30484407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917799
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952084
}}
}}
* {{medline-title
* {{medline-title
|title=N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation.
|title=[[APOE]] region molecular signatures of Alzheimer's disease across races/ethnicities.
|date=01.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30447351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31813627
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.11.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064423
}}
}}
* {{medline-title
* {{medline-title
|title=Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice.
|title=Varying Effects of [[APOE]] Alleles on Extreme Longevity in European Ethnicities.
|date=20.11.2018
|date=13.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31724059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330482
}}
}}
* {{medline-title
* {{medline-title
|title=Metformin Is a Direct [[SIRT1]]-Activating Compound: Computational Modeling and Experimental Validation.
|title=Prospective Evaluation of Cognitive Health and Related Factors in Elderly at Risk for Developing Alzheimer's Dementia: A Longitudinal Cohort Study.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30459716
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31686098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232372
|full-text-url=https://sci-hub.do/10.14283/jpad.2019.31
}}
}}
* {{medline-title
* {{medline-title
|title=Hsp90 Stabilizes [[SIRT1]] Orthologs in Mammalian Cells and [i]C. elegans[/i].
|title=Association of Cardiovascular and Alzheimer's Disease Risk Factors with Intracranial Arterial Blood Flow in Whites and African Americans.
|date=20.11.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463299
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31658057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081660
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuins and NAD  in the Development and Treatment of Metabolic and Cardiovascular Diseases.
|title=Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease?
|date=14.09.2018
|date=17.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355082
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31613323
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206880
|full-text-url=https://sci-hub.do/10.1093/gerona/glz244
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT1]] deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis.
|title=Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study.
|date=12.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30295421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31630996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260920
|full-text-url=https://sci-hub.do/10.1016/j.jalz.2019.07.018
}}
}}
* {{medline-title
* {{medline-title
|title=Prevention of Senescence in Vasculature Through Quiescence.
|title=Prospective Memory: Age related change is influenced by [[APOE]] genotype.
|date=10.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30259779
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31578124
|full-text-url=https://sci-hub.do/10.1089/rej.2018.2138
|full-text-url=https://sci-hub.do/10.1080/13825585.2019.1671305
}}
}}
* {{medline-title
* {{medline-title
|title=Melatonin and inflammation-Story of a double-edged blade.
|title=Education Moderates the Relation Between [[APOE]] ɛ4 and Memory in Nondemented Non-Hispanic Black Older Adults.
|date=11.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31594222
|full-text-url=https://sci-hub.do/10.1111/jpi.12525
|full-text-url=https://sci-hub.do/10.3233/JAD-190415
}}
}}
* {{medline-title
* {{medline-title
|title=[[ALDH2]] mediates the dose-response protection of chronic ethanol against endothelial senescence through [[SIRT1]]/p53 pathway.
|title=Apolipoprotein E ε4 allele effects on longitudinal cognitive trajectories are sex and age dependent.
|date=12.10.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31561966
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.081
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561018
}}
}}
* {{medline-title
* {{medline-title
|title=Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats.
|title=Interactive effect of age and [[APOE]]-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects.
|date=08.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30196020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520917
|full-text-url=https://sci-hub.do/10.1016/j.jphs.2018.08.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742967
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial [[SIRT1]] prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells.
|title=[[APOE]] modifies the interaction of entorhinal cerebral blood flow and cortical thickness on memory function in cognitively normal older adults.
|date=01.03.2019
|date=15.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165439
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31493534
|full-text-url=https://sci-hub.do/10.1093/cvr/cvy212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819270
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Ginsenoside Rg3 on fatigue resistance and [[SIRT1]] in aged rats.
|title=When time's arrow doesn't bend: [[APOE]]-ε4 influences episodic memory before old age.
|date=01.11.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30144466
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31473197
|full-text-url=https://sci-hub.do/10.1016/j.tox.2018.08.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817416
}}
}}
* {{medline-title
* {{medline-title
|title=[[PARP1]] inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD  levels and increasing [[SIRT1]] activity.
|title=Cognitive-Motor Integration Performance Is Affected by Sex, [[APOE]] Status, and Family History of Dementia.
|date=23.08.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30139380
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31424400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107962
|full-text-url=https://sci-hub.do/10.3233/JAD-190403
}}
}}
* {{medline-title
* {{medline-title
|title=Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing [[SIRT1]] and [[SIRT3]] expression.
|title=Associations among amyloid status, age, and longitudinal regional brain atrophy in cognitively unimpaired older adults.
|date=10.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30132522
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31437719
|full-text-url=https://sci-hub.do/10.3892/mmr.2018.9390
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198229
}}
}}
* {{medline-title
* {{medline-title
|title=Liver regeneration in aged mice: new insights.
|title=Cognitive function and neuropathological outcomes: a forward-looking approach.
|date=28.08.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30157472
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31435771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851487
}}
}}
* {{medline-title
* {{medline-title
|title=Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit's Heart and Liver.
|title=[[APOE]] gene-dependent BOLD responses to a breath-hold across the adult lifespan.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31408838
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079382
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699560
}}
}}
* {{medline-title
* {{medline-title
|title=Defect of [[SIRT1]]-FoxO3a axis is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated cellular senescence and nematode aging.
|title=Medial temporal lobe atrophy and posterior atrophy scales normative values.
|date=04.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30103847
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31382240
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690662
}}
}}
* {{medline-title
* {{medline-title
|title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls.
|title=Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study.
|date=10.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385647
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475
|full-text-url=https://sci-hub.do/10.1002/da.22912
}}
}}
* {{medline-title
* {{medline-title
|title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes.
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity.
|date=01.05.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3
}}
}}
* {{medline-title
* {{medline-title
|title=[[PGC]]-1α Protects [[RPE]] Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis.
|title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity.
|date=07.08.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087287
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121367
|full-text-url=https://sci-hub.do/10.1089/cell.2019.0010
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of oral appliance on circulating leukocyte telomere length and [[SIRT1]] in obstructive sleep apnea.
|title=Late life insulin resistance and Alzheimer's disease and dementia: The Kuakini Honolulu heart program.
|date=03.2019
|date=15.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030618
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31284182
|full-text-url=https://sci-hub.do/10.1007/s00784-018-2560-5
|full-text-url=https://sci-hub.do/10.1016/j.jns.2019.06.031
}}
}}
* {{medline-title
* {{medline-title
|title=miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating [[SIRT1]] (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase).
|title=Latent Classes of Cognitive Functioning Among Depressed Older Adults Without Dementia.
|date=09.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30026277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31232250
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.311298
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733620
}}
}}
* {{medline-title
* {{medline-title
|title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis.
|title=Lifespan Intellectual Factors, Genetic Susceptibility, and Cognitive Phenotypes in Aging: Implications for Interventions.
|date=12.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31214016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554280
}}
}}
* {{medline-title
* {{medline-title
|title=Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/[[SIRT1]] signaling pathway.
|title=Cyclic O  exposure synergizes with aging leading to memory impairment in male [[APOE]] ε3, but not [[APOE]] ε4, targeted replacement mice.
|date=06.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31207469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732233
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuin 1 and Alzheimer's disease: An up-to-date review.
|title=Alzheimer's disease and symbiotic microbiota: an evolutionary medicine perspective.
|date=10.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30007474
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31180143
|full-text-url=https://sci-hub.do/10.1016/j.npep.2018.07.001
|full-text-url=https://sci-hub.do/10.1111/nyas.14129
}}
}}
* {{medline-title
* {{medline-title
|title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans.
|title=The role of [[APOE]] in transgenic mouse models of AD.
|date=10.2018
|date=10.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31150730
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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717006
}}
}}
* {{medline-title
* {{medline-title
|title=Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-[[SIRT1]]-eNOS pathway.
|title=Sex differences in mixed neuropathologies in community-dwelling older adults.
|date=09.2018
|date=15.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29992759
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111868
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636678
}}
}}
* {{medline-title
* {{medline-title
|title=Serum containing Buyang Huanwu decoction prevents age-associated migration and invasion of human vascular smooth muscle cells by up regulating [[SIRT1]] expression.
|title=Women Outperform Men in Verbal Episodic Memory Even in Oldest-Old Age: 13-Year Longitudinal Results of the AgeCoDe/AgeQualiDe Study.
|date=17.07.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952352
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31127762
|full-text-url=https://sci-hub.do/10.5582/bst.2018.01063
|full-text-url=https://sci-hub.do/10.3233/JAD-180949
}}
}}
* {{medline-title
* {{medline-title
|title=Role of accelerated aging in limb muscle wasting of patients with COPD.
|title=[[APOE]] Effect on Amyloid-β PET Spatial Distribution, Deposition Rate, and Cut-Points.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31127775
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820
|full-text-url=https://sci-hub.do/10.3233/JAD-181282
}}
}}
* {{medline-title
* {{medline-title
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells.
|title=Sex differences in the association of [[APOE]] ε4 genotype with longitudinal hippocampal atrophy in cognitively normal older people.
|date=15.09.2018
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102429
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031
|full-text-url=https://sci-hub.do/10.1111/ene.13987
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal stem cells confer resistance to doxorubicin-induced cardiac senescence by inhibiting microRNA-34a.
|title=Predictors and Implications of Accelerated Cognitive Aging.
|date=06.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29928373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31007841
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004710
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469682
}}
}}
* {{medline-title
* {{medline-title
|title=The circadian clock in adult neural stem cell maintenance.
|title=Association of Cortical β-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease.
|date=02.2019
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29886147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009033
|full-text-url=https://sci-hub.do/10.1016/j.pneurobio.2018.05.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583061
}}
}}
* {{medline-title
* {{medline-title
|title=Resveratrol reduces senescence-associated secretory phenotype by [[SIRT1]]/NF-κB pathway in gut of the annual fish Nothobranchius guentheri.
|title=Sex differences in the association between amyloid and longitudinal brain volume change in cognitively normal older adults.
|date=09.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29908321
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30927602
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.06.027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444285
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of [[NAMPT]] in aging retinal pigment epithelium reduces NAD  availability and promotes cellular senescence.
|title=Region-specific association between basal blood insulin and cerebral glucose metabolism in older adults.
|date=12.06.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905535
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30904824
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046249
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434096
}}
}}
* {{medline-title
* {{medline-title
|title=Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes.
|title=Association between [[APOE]] e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity.
|date=06.2018
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860669
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30903549
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572345
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT1]], miR-132 and miR-212 link human longevity to Alzheimer's Disease.
|title=Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging.
|date=31.05.2018
|date=28.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29855513
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923322
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438979
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence.
|title=Nuances in Alzheimer's Genetic Risk Reveal Differential Predictions of Non-demented Memory Aging Trajectories: Selective Patterns by [[APOE]] Genotype and Sex.
|date=09.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29851177
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30873923
|full-text-url=https://sci-hub.do/10.1002/cbin.10999
|full-text-url=https://sci-hub.do/10.2174/1567205016666190315094452
}}
}}
* {{medline-title
* {{medline-title
|title=Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial Function.
|title=A prospective study of focal brain atrophy, mobility and fitness.
|date=09.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797808
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30861232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973912
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586507
}}
}}
* {{medline-title
* {{medline-title
|title=Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/[[SIRT1]]/[[PGC]]-1a Pathway in Skeletal Muscle from Naturally Aging Rats.
|title=10-year follow-up of the Super-Seniors Study: compression of morbidity and genetic factors.
|date=2018
|date=28.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29806860
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30819100
|full-text-url=https://sci-hub.do/10.1007/s12603-018-1015-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394013
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT1]] reverses senescence via enhancing autophagy and attenuates oxidative stress-induced apoptosis through promoting p53 degradation.
|title=Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time.
|date=01.10.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29803744
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30814948
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.05.174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381047
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers.
|title=Taste receptors, innate immunity and longevity: the case of [[TAS2R16]] gene.
|date=08.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774638
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30833980
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052398
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387736
}}
}}
* {{medline-title
* {{medline-title
|title=Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition.
|title=The Role of [[APOE]]4 in Disrupting the Homeostatic Functions of Astrocytes and Microglia in Aging and Alzheimer's Disease.
|date=07.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29753753
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30804776
|full-text-url=https://sci-hub.do/10.1016/j.neubiorev.2018.05.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378415
}}
}}
* {{medline-title
* {{medline-title
|title=Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of [[SIRT1]].
|title=The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals.
|date=2017
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29725214
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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486870
}}
}}
* {{medline-title
* {{medline-title
|title=Role of hypothalamus in aging and its underlying cellular mechanisms.
|title=Opposing Roles of apolipoprotein E in aging and neurodegeneration.
|date=01.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29729230
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760557
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.04.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374993
}}
}}
* {{medline-title
* {{medline-title
|title=The variable role of [[SIRT1]] in the maintenance and differentiation of mesenchymal stem cells.
|title=Effects of [[APOE]] on cognitive aging in community-dwelling older adults.
|date=04.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29715067
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30730162
|full-text-url=https://sci-hub.do/10.2217/rme-2017-0128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513314
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuins in Renal Health and Disease.
|title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.
|date=07.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608707
}}
}}
* {{medline-title
* {{medline-title
|title=Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, [[SIRT1]], [[SIRT3]], and VEGF in the Substantia Nigra.
|title=Apolipoprotein E4 Mediates the Association Between Midlife Dyslipidemia and Cerebral Amyloid in Aging Women.
|date=10.11.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659739
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30689578
|full-text-url=https://sci-hub.do/10.1093/gerona/gly072
|full-text-url=https://sci-hub.do/10.3233/JAD-180815
}}
}}
* {{medline-title
* {{medline-title
|title=MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells.
|title=Apolipoprotein E gene in physiological and pathological aging.
|date=03.04.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615114
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30658061
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883541
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.01.005
}}
}}
* {{medline-title
* {{medline-title
|title=Natural products with anti-aging potential: Affected targets and molecular mechanisms.
|title=Spatial patterns of white matter hyperintensities associated with Alzheimer's disease risk factors in a cognitively healthy middle-aged cohort.
|date=01.11.2018
|date=24.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29597027
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30678723
|full-text-url=https://sci-hub.do/10.1016/j.biotechadv.2018.03.012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346579
}}
}}
* {{medline-title
* {{medline-title
|title=[Effect of microRNA-34a/[[SIRT1]]/p53 signal pathway on notoginsenoside R₁ delaying vascular endothelial cell senescence].
|title=The Role of MRI Biomarkers and Their Interactions with Cognitive Status and [[APOE]] ε4 in Nondemented Elderly Subjects.
|date=02.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29600625
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673663
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180110.001
|full-text-url=https://sci-hub.do/10.1159/000495754
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT1]] and microRNAs: The role in breast, lung and prostate cancers.
|title=Longitudinal tau accumulation and atrophy in aging and alzheimer disease.
|date=01.06.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29574020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30597624
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.03.023
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579738
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}}
* {{medline-title
* {{medline-title
|title=Leukotriene D4 induces cellular senescence in osteoblasts.
|title=Apolipoprotein E Genotypes, Age, Race, and Cognitive Decline in a Population Sample.
|date=05.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587204
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30584655
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2017.12.027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813761
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}}
* {{medline-title
* {{medline-title
|title=Impairment of an Endothelial NAD -H S Signaling Network Is a Reversible Cause of Vascular Aging.
|title=Predictors of neurodegeneration differ between cognitively normal and subsequently impaired older adults.
|date=22.03.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570999
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30580127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394867
}}
}}
* {{medline-title
* {{medline-title
|title=Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas.
|title=Vascular burden and [[APOE]] ε4 are associated with white matter microstructural decline in cognitively normal older adults.
|date=08.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564694
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557663
|full-text-url=https://sci-hub.do/10.1007/s11102-018-0881-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601608
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}}
* {{medline-title
* {{medline-title
|title=Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.
|title=Responses to executive demand in young adulthood differ by [[APOE]] genotype.
|date=06.03.2018
|date=15.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29514072
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472114
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|full-text-url=https://sci-hub.do/10.1016/j.bbr.2018.11.033
}}
}}
* {{medline-title
* {{medline-title
|title=Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming.
|title=Mild Cognitive Impairment that Does Not Progress to Dementia: A Population-Based Study.
|date=05.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444944
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367026
}}
}}
* {{medline-title
* {{medline-title
|title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway.
|title=Neuropathologic, genetic, and longitudinal cognitive profiles in primary age-related tauopathy (PART) and Alzheimer's disease.
|date=2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30465754
|full-text-url=https://sci-hub.do/10.1159/000487559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542566
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}}
* {{medline-title
* {{medline-title
|title=The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system.
|title=Independent associations of [[TOMM40]] and [[APOE]] variants with body mass index.
|date=03.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407880
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30462377
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2018.01.043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351823
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}}
* {{medline-title
* {{medline-title
|title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction.
|title=Apolipoprotein E genotype moderates the association between dietary polyunsaturated fat and brain function: an exploration of cerebral glutamate and cognitive performance.
|date=04.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30465491
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531361
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}}
* {{medline-title
* {{medline-title
|title=Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes.
|title=Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults.
|date=03.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29331588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354979
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2017.12.021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101979
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}}
* {{medline-title
* {{medline-title
|title=Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress.
|title=The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description.
|date=20.02.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362018
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.01.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290855
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}}
* {{medline-title
* {{medline-title
|title=Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury.
|title=Report: NIA workshop on translating genetic variants associated with longevity into drug targets.
|date=11.01.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30374935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294726
}}
}}
* {{medline-title
* {{medline-title
|title=Acetylshikonin from Zicao attenuates cognitive impairment and hippocampus senescence in d-galactose-induced aging mouse model via upregulating the expression of [[SIRT1]].
|title=Dendritic spine remodeling accompanies Alzheimer's disease pathology and genetic susceptibility in cognitively normal aging.
|date=03.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325995
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30339964
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2018.01.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251733
}}
}}
* {{medline-title
* {{medline-title
|title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway.
|title=The ApoE ε4 Isoform: Can the Risk of Diseases be Reduced by Environmental Factors?
|date=03.2018
|date=01.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30321297
|full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0
|full-text-url=https://sci-hub.do/10.1093/gerona/gly226
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuins in Brain Aging and Neurological Disorders.
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|date=2017
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29283326
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|full-text-url=https://sci-hub.do/10.1615/CritRevEukaryotGeneExpr.2017019532
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
}}
}}
* {{medline-title
* {{medline-title
|title=[Aging-related change of erectile function and the expression of [[SIRT1]]].
|title=Amygdala subnuclei and healthy cognitive aging.
|date=12.2016
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29282911
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30291764
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865708
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans.
|title=[[APOE]] ɛ4, rs405509, and rs440446 promoter and intron-1 polymorphisms and dementia risk in a cohort of elderly Finns-Helsinki Birth Cohort Study.
|date=2017
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30293724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715387
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.09.005
}}
}}
* {{medline-title
* {{medline-title
|title=Maternal aging affects oocyte resilience to carbonyl cyanide-m-chlorophenylhydrazone -induced mitochondrial dysfunction in cows.
|title=The Cross-sectional and Longitudinal Associations Between IL-6, IL-10, and TNFα and Cognitive Outcomes in the Mayo Clinic Study of Aging.
|date=2017
|date=12.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182624
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30256904
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625589
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating [[SIRT1]] activity and antioxidant gene expression in mouse cells.
|title=The effect of midlife cardiovascular risk factors on white matter hyperintensity volume and cognition two decades later in normal ageing women.
|date=12.2017
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29178516
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30259291
|full-text-url=https://sci-hub.do/10.1111/gtc.12542
|full-text-url=https://sci-hub.do/10.1007/s11682-018-9970-5
}}
}}
* {{medline-title
* {{medline-title
|title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™).
|title=Sex and age interact to determine clinicopathologic differences in Alzheimer's disease.
|date=04.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30219939
|full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280837
}}
}}
* {{medline-title
* {{medline-title
|title=Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through [[SIRT1]].
|title=Relationship Between Amyloid-β Positivity and Progression to Mild Cognitive Impairment or Dementia over 8 Years in Cognitively Normal Older Adults.
|date=2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29118911
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30149452
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666058
|full-text-url=https://sci-hub.do/10.3233/JAD-180507
}}
}}
* {{medline-title
* {{medline-title
|title=Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating [[SIRT1]]-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation.
|title=Lifetime Risk Factors for Functional and Cognitive Outcomes in Patients with Alzheimer's Disease.
|date=14.11.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30149448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707715
|full-text-url=https://sci-hub.do/10.3233/JAD-180303
}}
}}
* {{medline-title
* {{medline-title
|title=Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice.
|title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau.
|date=13.10.2017
|date=03.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29137352
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663524
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978
}}
}}
* {{medline-title
* {{medline-title
|title=O-GlcNAcylation of [[SIRT1]] enhances its deacetylase activity and promotes cytoprotection under stress.
|title=Childhood socioeconomic status and genetic risk for poorer cognition in later life.
|date=14.11.2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29133780
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048844
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684413
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536306
}}
}}
* {{medline-title
* {{medline-title
|title=Aging as an Epigenetic Phenomenon.
|title=Diffuse Amyloid-β Plaques, Neurofibrillary Tangles, and the Impact of [[APOE]] in Elderly Persons' Brains Lacking Neuritic Amyloid Plaques.
|date=10.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040735
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537103
}}
}}
* {{medline-title
* {{medline-title
|title=MeCP2 mediated dysfunction in senescent EPCs.
|title=Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain.
|date=03.10.2017
|date=24.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29108229
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30041668
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667962
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057096
}}
}}
* {{medline-title
* {{medline-title
|title=Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress.
|title=Dual-Task Gait and Alzheimer's Disease Genetic Risk in Cognitively Normal Adults: A Pilot Study.
|date=01.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063982
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30010120
|full-text-url=https://sci-hub.do/10.1007/s10571-017-0557-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500574
}}
}}
* {{medline-title
* {{medline-title
|title=A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction.
|title=Higher Aortic Stiffness Is Related to Lower Cerebral Blood Flow and Preserved Cerebrovascular Reactivity in Older Adults.
|date=12.09.2017
|date=30.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29029466
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30018169
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394409
}}
}}
* {{medline-title
* {{medline-title
|title=Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence.
|title=Physical activity effects on the individual alpha peak frequency of older adults with and without genetic risk factors for Alzheimer's Disease: A MEG study.
|date=17.10.2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29041897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645932
|full-text-url=https://sci-hub.do/10.1016/j.clinph.2018.06.026
}}
}}
* {{medline-title
* {{medline-title
|title=Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts.
|title=Racial and Ethnic Disparities in Dementia Risk Among Individuals With Low Education.
|date=28.12.2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28964787
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30005921
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2017.09.027
|full-text-url=https://sci-hub.do/10.1016/j.jagp.2018.05.011
}}
}}
* {{medline-title
* {{medline-title
|title=Blocking [[SIRT1]] inhibits cell proliferation and promotes aging through the PI3K/AKT pathway.
|title=Increased CAIDE dementia risk, cognition, CSF biomarkers, and vascular burden in healthy adults.
|date=01.12.2017
|date=17.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28962864
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898969
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.09.037
|full-text-url=https://sci-hub.do/10.1212/WNL.0000000000005824
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT1]] is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis.
|title=Differential 5-year brain atrophy rates in cognitively declining and stable [[APOE]]-ε4 elders.
|date=2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28937996
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29911873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126943
}}
}}
* {{medline-title
* {{medline-title
|title=[Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell].
|title=Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity.
|date=02.2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952264
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890178
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.2017.0012
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.002
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT1]] is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity.
|title=Using event-related fMRI to examine sustained attention processes and effects of [[APOE]] ε4 in young adults.
|date=05.02.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28923345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29856823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756502
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983530
}}
}}
* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.
|date=15.11.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway.
|title=White matter microstructure is altered in cognitively normal middle-aged [[APOE]]-ε4 homozygotes.
|date=11.2017
|date=24.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847722
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29793545
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.032
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968505
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats.
|title=Effects of lifetime cumulative ginseng intake on cognitive function in late life.
|date=03.2018
|date=24.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808887
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29793529
|full-text-url=https://sci-hub.do/10.1007/s11481-017-9759-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968575
}}
}}
* {{medline-title
* {{medline-title
|title=Aquatide Activation of [[SIRT1]] Reduces Cellular Senescence through a [[SIRT1]]-[[FOXO1]]-Autophagy Axis.
|title=Apolipoprotein E region molecular signatures of Alzheimer's disease.
|date=01.09.2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822991
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797398
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590795
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052488
}}
}}
* {{medline-title
* {{medline-title
|title=Obesity and aging diminish sirtuin 1 ([[SIRT1]])-mediated deacetylation of [[SIRT3]], leading to hyperacetylation and decreased activity and stability of [[SIRT3]].
|title=Does incipient dementia explain normal cognitive decline determinants? Lothian birth cohort 1921.
|date=20.10.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808064
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29745686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655509
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001941
}}
}}
* {{medline-title
* {{medline-title
|title=Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging.
|title=An 18-mo randomized, double-blind, placebo-controlled trial of DHA-rich fish oil to prevent age-related cognitive decline in cognitively normal older adults.
|date=10.08.2017
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28802039
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29722833
|full-text-url=https://sci-hub.do/10.1016/j.cell.2017.07.042
|full-text-url=https://sci-hub.do/10.1093/ajcn/nqx077
}}
}}
* {{medline-title
* {{medline-title
|title=High glucose and free fatty acids induce endothelial progenitor cell senescence via [[PGC]]-1α/[[SIRT1]] signaling pathway.
|title=The Role of Apolipoprotein E and Ethanol Exposure in Age-Related Changes in Choline Acetyltransferase and Brain-Derived Neurotrophic Factor Expression in the Mouse Hippocampus.
|date=10.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28786152
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717403
|full-text-url=https://sci-hub.do/10.1002/cbin.10833
|full-text-url=https://sci-hub.do/10.1007/s12031-018-1074-6
}}
* {{medline-title
|title=[[APOE]] genotype modifies the association between central arterial stiffening and cognition in older adults.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985659
}}
}}
==HR==
* {{medline-title
* {{medline-title
|title=Patients with hip fracture and total hip arthroplasty surgery differ in anthropometric, but not cardiovascular screening abnormalities.
|title=Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration.
|date=02.12.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33267795
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660940
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713041
|full-text-url=https://sci-hub.do/10.3233/JAD-171054
}}
}}
* {{medline-title
* {{medline-title
|title=Clinical Role of Lung Ultrasound for the Diagnosis and Prognosis of Coronavirus Disease Pneumonia in Elderly Patients: A Pivotal Study.
|title=Brain Aging and [[APOE]] ε4 Interact to Reveal Potential Neuronal Compensation in Healthy Older Adults.
|date=03.12.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33271558
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615896
|full-text-url=https://sci-hub.do/10.1159/000512209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869204
}}
}}
* {{medline-title
* {{medline-title
|title=The Relationship of Accelerometer-Assessed Standing Time With and Without Ambulation and Mortality: The WHI OPACH Study.
|title=Leisure-Time Physical Activity and the Risk of Incident Dementia: The Mayo Clinic Study of Aging.
|date=12.10.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33225345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29614667
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900557
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related myofiber atrophy in old mice is reversed by ten weeks voluntary high-resistance wheel running.
|title=Effects of [[APOE]]-ε4 allele load on brain morphology in a cohort of middle-aged healthy individuals with enriched genetic risk for Alzheimer's disease.
|date=09.11.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33181317
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29605385
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111150
|full-text-url=https://sci-hub.do/10.1016/j.jalz.2018.01.016
}}
}}
* {{medline-title
* {{medline-title
|title=Predicted Skeletal Muscle Mass and 4-Year Cardiovascular Disease Incidence in Middle-Aged and Elderly Participants of IKARIA Prospective Epidemiological Study: The Mediating Effect of Sex and Cardiometabolic Factors.
|title=[[APOE]] influences working memory in non-demented elderly through an interaction with [[SPON1]] rs2618516.
|date=27.10.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33121164
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866309
}}
}}
* {{medline-title
* {{medline-title
|title=Obesity is associated with early hip fracture risk in postmenopausal women: a 25-year follow-up.
|title=Altered effective connectivity anchored in the posterior cingulate cortex and the medial prefrontal cortex in cognitively intact elderly [[APOE]] ε4 carriers: a preliminary study.
|date=23.10.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33095419
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29549664
|full-text-url=https://sci-hub.do/10.1007/s00198-020-05665-w
|full-text-url=https://sci-hub.do/10.1007/s11682-018-9857-5
}}
}}
* {{medline-title
* {{medline-title
|title=ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells.
|title=Plasma Cortisol, Brain Amyloid-β, and Cognitive Decline in Preclinical Alzheimer's Disease: A 6-Year Prospective Cohort Study.
|date=09.2020
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33024871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29560886
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527645
|full-text-url=https://sci-hub.do/10.1016/j.bpsc.2016.08.006
}}
}}
* {{medline-title
* {{medline-title
|title=Effectiveness of adjuvant FOLFOX vs 5FU/LV in adults over age 65 with stage II and III colon cancer using a novel hybrid approach.
|title=Apolipoprotein E genotypes and longevity across dementia disorders.
|date=12.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33015888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29548722
|full-text-url=https://sci-hub.do/10.1002/pds.5148
|full-text-url=https://sci-hub.do/10.1016/j.jalz.2018.02.003
}}
}}
* {{medline-title
* {{medline-title
|title=Age, Frailty, and Comorbidity as Prognostic Factors for Short-Term Outcomes in Patients With Coronavirus Disease 2019 in Geriatric Care.
|title=Differential Effect of [[APOE]] ɛ4 Status and Elevated Pulse Pressure on Functional Decline in Cognitively Normal Older Adults.
|date=11.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32978065
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29562507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427570
|full-text-url=https://sci-hub.do/10.3233/JAD-170918
}}
}}
* {{medline-title
* {{medline-title
|title=Clinical and demographic parameters predict the progression from mild cognitive impairment to dementia in elderly patients.
|title=Functional segregation loss over time is moderated by [[APOE]] genotype in healthy elderly.
|date=12.09.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32918697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520911
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01697-8
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}}
* {{medline-title
* {{medline-title
|title=Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women.
|title=Dementia Prevalence in Greece: The Hellenic Longitudinal Investigation of Aging and Diet (HELIAD).
|date=01.12.2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528855
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526732
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000249
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}}
* {{medline-title
* {{medline-title
|title=High intensity interval training combined with L-citrulline supplementation: Effects on physical performance in healthy older adults.
|title=Atypical Localization and Dissociation between Glucose Uptake and Amyloid Deposition in Cognitively Normal [[APOE]]*E4 Homozygotic Elders Compared with Patients with Late-Onset Alzheimer's Disease.
|date=15.10.2020
|date=01-02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721549
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29497704
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111036
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}}
* {{medline-title
* {{medline-title
|title=Associations of blood pressure with risk of injurious falls in old age vary by functional status: A cohort study.
|title=Association between subjective memory assessment and associative memory performance: Role of ad risk factors.
|date=15.10.2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32738383
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29494182
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111038
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}}
* {{medline-title
* {{medline-title
|title=Epigenetic age acceleration and clinical outcomes in gliomas.
|title=Reduced Gray Matter Volume of the Thalamus and Hippocampal Region in Elderly Healthy Adults with no Impact of [[APOE]] ɛ4: A Longitudinal Voxel-Based Morphometry Study.
|date=2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32692766
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29480170
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|full-text-url=https://sci-hub.do/10.3233/JAD-161036
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}}
* {{medline-title
* {{medline-title
|title=Do Stairs Inhibit Seniors Who Live on Upper Floors From Going Out?
|title=Apolipoprotein E genotype does not moderate the associations of depressive symptoms, neuroticism and allostatic load with cognitive ability and cognitive aging in the Lothian Birth Cohort 1936.
|date=10.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32666833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29451880
|full-text-url=https://sci-hub.do/10.1177/1937586720936588
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}}
}}
* {{medline-title
* {{medline-title
|title=Age-specific acute changes in carotid-femoral pulse wave velocity with head-up tilt.
|title=A Network of Genetic Effects on Non-Demented Cognitive Aging: Alzheimer's Genetic Risk (CLU  CR1   PICALM) Intensifies Cognitive Aging Genetic Risk (COMT  BDNF) Selectively for [[APOE]]ɛ4 Carriers.
|date=07.07.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634245
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29480189
|full-text-url=https://sci-hub.do/10.1093/ajh/hpaa101
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}}
}}
* {{medline-title
* {{medline-title
|title=Pre-frailty status increases the risk of rehospitalization in patients after elective cardiac surgery without complication.
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=06.2020
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531126
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://sci-hub.do/10.1111/jocs.14550
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
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}}
* {{medline-title
* {{medline-title
|title=Comparative Performance of Creatinine-Based GFR Estimation Equations in Exceptional Longevity: The Rugao Longevity and Ageing Study.
|title=Genetic Variation in [[FOXO3]] is Associated with Self-Rated Health in a Population-Based Sample of Older Individuals.
|date=2020
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32546991
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266309
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}}
}}
* {{medline-title
* {{medline-title
|title=Sex-and race-specific associations of protein intake with change in muscle mass and physical function in older adults: the Health, Aging, and Body Composition (Health ABC) Study.
|title=[[APOE]] ε4 Genotype and Cognitive Reserve Effects on the Cognitive Functioning of Healthy Elders.
|date=01.07.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32520344
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29414814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326591
|full-text-url=https://sci-hub.do/10.1159/000481852
}}
}}
* {{medline-title
* {{medline-title
|title=Deterioration of bone microstructure by aging and menopause in Japanese healthy women: analysis by [[HR]]-pQCT.
|title=Distinct neural correlates of episodic memory among apolipoprotein E alleles in cognitively normal elderly.
|date=11.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32519249
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29396739
|full-text-url=https://sci-hub.do/10.1007/s00774-020-01115-z
|full-text-url=https://sci-hub.do/10.1007/s11682-017-9818-4
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}}
* {{medline-title
* {{medline-title
|title=Association between Low Protein Intake and Mortality in Patients with Type 2 Diabetes.
|title=Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.
|date=01.06.2020
|date=06.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32492838
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728673
}}
}}
* {{medline-title
* {{medline-title
|title=CAUSES, mortality rates and risk factors of death in community-dwelling Europeans aged 50 years and over: Results from the Survey of Health, Ageing and Retirement in Europe 2013-2015.
|title=Features associated with cognitive impairment and dementia in a community-based sample of illiterate elderly aged 75  years: the Pietà study.
|date=07-08.2020
|date=04-06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32325305
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29213893
|full-text-url=https://sci-hub.do/10.1016/j.archger.2020.104035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619119
}}
}}
* {{medline-title
* {{medline-title
|title=Estimation of Wave Condition Number From Pressure Waveform Alone and Its Changes With Advancing Age in Healthy Women and Men.
|title=Epistasis, physical capacity-related genes and exceptional longevity: [[FNDC5]] gene interactions with candidate genes FOXOA3 and [[APOE]].
|date=2020
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32328003
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143599
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161432
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688477
}}
}}
* {{medline-title
* {{medline-title
|title=Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition.
|title=Neuronal hyperactivity due to loss of inhibitory tone in [[APOE]]4 mice lacking Alzheimer's disease-like pathology.
|date=07.2020
|date=13.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32333827
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29133888
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327915
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684208
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of artificial dawn light on cardiovascular function, alertness, and balance in middle-aged and older adults.
|title=Green space and cognitive ageing: A retrospective life course analysis in the Lothian Birth Cohort 1936.
|date=13.10.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32307533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29128786
|full-text-url=https://sci-hub.do/10.1093/sleep/zsaa082
|full-text-url=https://sci-hub.do/10.1016/j.socscimed.2017.10.038
}}
}}
* {{medline-title
* {{medline-title
|title=Heart Rate Performance Curve Is Dependent on Age, Sex, and Performance.
|title=Preclinical effects of [[APOE]] ε4 on cerebrospinal fluid Aβ42 concentrations.
|date=2020
|date=23.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32300582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29061195
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144539
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654097
}}
}}
* {{medline-title
* {{medline-title
|title=Physical activity trajectories, mortality, hospitalization, and disability in the Toledo Study of Healthy Aging.
|title=Genome-wide meta-analysis associates HLA-DQA1/DRB1 and [[LPA]] and lifestyle factors with human longevity.
|date=08.2020
|date=13.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32163233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29030599
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}}
}}
* {{medline-title
* {{medline-title
|title=U-Shaped Association of Plasma Testosterone, and no Association of Plasma Estradiol, with Incidence of Fractures in Men.
|title=Phenome and genome based studies into human ageing and longevity: An overview.
|date=01.05.2020
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32155267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28951210
|full-text-url=https://sci-hub.do/10.1210/clinem/dgaa115
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2017.09.017
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}}
* {{medline-title
* {{medline-title
|title=Pregnancy-Related Bone Mineral and Microarchitecture Changes in Women Aged 30 to 45 Years.
|title=A Tale of Two Genes: Microglial Apoe and Trem2.
|date=07.2020
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32119748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28930654
|full-text-url=https://sci-hub.do/10.1002/jbmr.3998
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2017.08.015
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of the world record time for combined father and son marathon.
|title=The Association of Apolipoprotein E Gene Polymorphism With Cognitive Performance in Nondemented Polish Adults Aged 55 to 75.
|date=01.02.2020
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28844148
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00819.2019
|full-text-url=https://sci-hub.do/10.1177/0091415017724548
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related reductions in heart rate variability do not worsen during exposure to humid compared to dry heat: A secondary analysis.
|title=Cognitive Aging in Black and White Americans: Cognition, Cognitive Decline, and Incidence of Alzheimer Disease Dementia.
|date=2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31934605
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28863046
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718953
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* {{medline-title
* {{medline-title
|title=Efficacy and Safety of Dapagliflozin in the Elderly: Analysis From the DECLARE-TIMI 58 Study.
|title=Alzheimer's Disease Biomarkers Interactively Influence Physical Activity, Mobility, and Cognition Associations in a Non-Demented Aging Population.
|date=02.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843945
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28800331
|full-text-url=https://sci-hub.do/10.2337/dc19-1476
|full-text-url=https://sci-hub.do/10.3233/JAD-170130
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}}
* {{medline-title
* {{medline-title
|title=Validity of Prediction Equations of Maximal Heart Rate in Physically Active Female Adolescents and the Role of Maturation.
|title=Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort.
|date=13.11.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31766291
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28800603
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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553750
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}}
* {{medline-title
* {{medline-title
|title=Base excision repair but not DNA double-strand break repair is impaired in aged human adipose-derived stem cells.
|title=Putting attention in the spotlight: The influence of [[APOE]] genotype on visual search in mid adulthood.
|date=02.2020
|date=15.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31782607
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28750833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996963
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2017.07.015
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* {{medline-title
* {{medline-title
|title=Urban-Rural Differences in Hip Fracture Mortality: A Nationwide NOREPOS Study.
|title=Left Frontal Hub Connectivity during Memory Performance Supports Reserve in Aging and Mild Cognitive Impairment.
|date=11.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31768493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28731448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611800
}}
}}
* {{medline-title
* {{medline-title
|title=Malnutrition as a Strong Predictor of the Onset of Sarcopenia.
|title=Physical activity modifies the influence of apolipoprotein E ε4 allele and type 2 diabetes on dementia and cognitive impairment among older Mexican Americans.
|date=27.11.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783482
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28692819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950107
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750101
}}
}}
* {{medline-title
* {{medline-title
|title=Acclimation to a thermoneutral environment abolishes age-associated alterations in heart rate and heart rate variability in conscious, unrestrained mice.
|title=Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition.
|date=02.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31776883
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671114
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031176
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523839
}}
}}
* {{medline-title
* {{medline-title
|title=Long-term dementia risk prediction by the LIBRA score: A 30-year follow-up of the CAIDE study.
|title=Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and [[APOE]] genotype in cognitively normal adults.
|date=02.2020
|date=03.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31736136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28673336
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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496132
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* {{medline-title
* {{medline-title
|title=Kidney function and its association to imminent, short- and long-term fracture risk-a longitudinal study in older women.
|title=Differential Aging Trajectories of Modulation of Activation to Cognitive Challenge in [[APOE]] ε4 Groups: Reduced Modulation Predicts Poorer Cognitive Performance.
|date=01.2020
|date=19.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754754
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28652414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946753
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518419
}}
}}
* {{medline-title
* {{medline-title
|title=Oxidatively Damaged DNA/RNA and 8-Isoprostane Levels Are Associated With the Development of Type 2 Diabetes at Older Age: Results From a Large Cohort Study.
|title=Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults.
|date=01.2020
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28648916
|full-text-url=https://sci-hub.do/10.2337/dc19-1379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564417
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* {{medline-title
|title=[[APOE]] gene polymorphism in long-lived individuals from a central China population.
|date=12.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28607446
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468225
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}}
* {{medline-title
* {{medline-title
|title=Associations of vigorous physical activity with all-cause, cardiovascular and cancer mortality among 64 913 adults.
|title=Disrupted white matter structural networks in healthy older adult [[APOE]] ε4 carriers - An international multicenter DTI study.
|date=2019
|date=15.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31548909
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28596117
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733336
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2017.05.048
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}}
* {{medline-title
* {{medline-title
|title=Reduced cerebrovascular and cardioventilatory responses to intermittent hypoxia in elderly.
|title=Effect of [[APOE]] ε4 Genotype on Metabolic Biomarkers in Aging and Alzheimer's Disease.
|date=01.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31557538
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28550261
|full-text-url=https://sci-hub.do/10.1016/j.resp.2019.103306
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776708
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}}
* {{medline-title
* {{medline-title
|title=Vestibulo-sympathetic reflex in patients with bilateral vestibular loss.
|title=[[APOE]] moderates compensatory recruitment of neuronal resources during working memory processing in healthy older adults.
|date=01.11.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31513442
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28528773
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00466.2019
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.04.015
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}}
* {{medline-title
* {{medline-title
|title=Heart rate and blood pressure in male Ts65Dn mice: a model to investigate cardiovascular responses in Down syndrome.
|title=General cognitive status among Baby boomers and pre-boomers in Taiwan: the interplay between mid-life socioeconomic status and city residence.
|date=09.2019
|date=25.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31496136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28545399
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}}
* {{medline-title
* {{medline-title
|title=Body weight at 10 years of age and change in body composition between 8 and 10 years of age were related to survival in a longitudinal study of 39 Labrador retriever dogs.
|title=[[APOE]] ε4 Modulation of Training Outcomes in Several Cognitive Domains in a Sample of Cognitively Intact Older Adults.
|date=09.09.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500653
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28550244
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}}
* {{medline-title
* {{medline-title
|title=Dietary diversity offsets the adverse mortality risk among older indigenous Taiwanese.
|title=[[APOE]] Genotype and Nonrespiratory Sleep Parameters in Cognitively Intact Older Adults.
|date=2019
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31464406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28482100
|full-text-url=https://sci-hub.do/10.6133/apjcn.201909_28(3).0019
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* {{medline-title
* {{medline-title
|title=Independent and joint effects of vascular and cardiometabolic risk factor pairs for risk of all-cause dementia: a prospective population-based study.
|title=The [[APOE]] ε4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease.
|date=10.2019
|date=19.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31455442
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28453930
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* {{medline-title
* {{medline-title
|title=Work Ability and Job Survival: Four-Year Follow-Up.
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|title=Predictivity of bioimpedance phase angle for incident disability in older adults.
|title=Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals.
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|title=Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study.
|title=Plasma apolipoproteins and physical and cognitive health in very old individuals.
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|title=Birthweight in offspring and cardiovascular mortality in their parents, aunts and uncles: a family-based cohort study of 1.35 million births.
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|title=Younger- vs Older-Old Patients with Heart Failure with Preserved Ejection Fraction.
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|title=Comparison of Immune Checkpoint Inhibitors between Older and Younger Patients with Advanced or Metastatic Lung Cancer: A Systematic Review and Meta-Analysis.
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|title=Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study.
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* {{medline-title
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|title=Fed and fasted states on heart rate variability, hemodynamic heart rate and blood pressure in adults submitted to moderate aerobic exercise.
|title=Interaction of [[APOE]] e4 and poor glycemic control predicts white matter hyperintensity growth from 73 to 76.
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|title=Structure Characterization and Action Mechanism of an Antiaging New Compound from [i]Gastrodia elata[/i] Blume.
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|title=Effects of Whole-Body Vibration Therapy on Distal Tibial Myotendinous Density and Volume: A Randomized Controlled Trial in Postmenopausal Women.
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|title=Smoking cessation and risk of recurrent cardiovascular events and mortality after a first manifestation of arterial disease.
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|full-text-url=https://sci-hub.do/10.1016/j.ahj.2019.03.019
|full-text-url=https://sci-hub.do/10.2174/1567205014666170309115016
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|title=The Association of Aromatic Amino Acids with Incident Hip Fracture, aBMD, and Body Composition from the Cardiovascular Health Study.
|title=Prospective associations of exercise and depressive symptoms in older adults: the role of apolipoprotein E4.
|date=08.2019
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* {{medline-title
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|title=Impact of handgrip strength on cardiovascular, cancer and all-cause mortality in the Korean longitudinal study of ageing.
|title=Psychosocial Risk and Protective Factors and Incident Mild Cognitive Impairment and Dementia in Community Dwelling Elderly: Findings from the Singapore Longitudinal Ageing Study.
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* {{medline-title
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|title=Vitamin K Status and Mobility Limitation and Disability in Older Adults: The Health, Aging, and Body Composition Study.
|title=Demographic, phenotypic, and genetic characteristics of centenarians in Okinawa and Honshu, Japan: Part 2 Honshu, Japan.
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* {{medline-title
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|title=Effects of a clinical medication review focused on personal goals, quality of life, and health problems in older persons with polypharmacy: A randomised controlled trial (DREAMeR-study).
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
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}}
* {{medline-title
* {{medline-title
|title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair.
|title=CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of [[GRN]]/P[[GRN]].
|date=06.2019
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|title=Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old.
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* {{medline-title
* {{medline-title
|title=Relationship Between Sex Steroids and Deterioration of Bone Microarchitecture in Older Men: The Prospective STRAMBO Study.
|title=A Multi-Cohort Study of ApoE ɛ4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease.
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* {{medline-title
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|title=Sex And Prognostic Significance of Self-Reported Frailty in Non-ST-Segment Elevation Acute Coronary Syndromes: Insights From the TRILOGY ACS Trial.
|title=The rs1277306 Variant of the [[REST]] Gene Confers Susceptibility to Cognitive Aging in an Elderly Taiwanese Population.
|date=04.2019
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* {{medline-title
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|title=Plasma 25-Hydroxyvitamin D Concentrations Are Inversely Associated with All-Cause Mortality among a Prospective Cohort of Chinese Adults Aged ≥80 Years.
|title=The Interactive Effects of Age and [[PICALM]] rs541458 Polymorphism on Cognitive Performance, Brain Structure, and Function in Non-demented Elderly.
|date=01.06.2019
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|title=Sex-specific associations between body mass index and death before life expectancy: a comparative study from the USA and Sweden.
|title=Age differences in arterial and venous extra-cerebral blood flow in healthy adults: contributions of vascular risk factors and genetic variants.
|date=2019
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|title=Correlation between patients' age and cancer immunotherapy efficacy.
|title=High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors.
|date=2019
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30906662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28129359
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* {{medline-title
* {{medline-title
|title=Understanding the responsiveness of nitric oxide to acute eccentric resistance exercise in elderly obese women.
|title=Executive function performance and change in aging is predicted by apolipoprotein E, intensified by catechol-O-methyltransferase and brain-derived neurotrophic factor, and moderated by age and lifestyle.
|date=20.06.2016
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30873464
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}}
* {{medline-title
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|title=Age-dependent changes in metabolite profile and lipid saturation in dystrophic mice.
|title=The Elusive Nature of [[APOE]] ε4 in Mid-adulthood: Understanding the Cognitive Profile.
|date=05.2019
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30848538
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28059047
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|full-text-url=https://sci-hub.do/10.1017/S1355617716000990
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}}
* {{medline-title
* {{medline-title
|title=Investigating dose-response effects of multimodal exercise programs on health-related quality of life in older adults.
|title=Motor timing intraindividual variability in amnestic mild cognitive impairment and cognitively intact elders at genetic risk for Alzheimer's disease.
|date=2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30774322
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28052734
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352872
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916765
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}}
* {{medline-title
* {{medline-title
|title=Methylation-Based Biological Age and Breast Cancer Risk.
|title=Screening Younger Individuals in a Primary Care Setting Flags Putative Dementia Cases and Correlates Gastrointestinal Diseases with Poor Cognitive Performance.
|date=01.10.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30794318
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27907913
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792078
|full-text-url=https://sci-hub.do/10.1159/000452485
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* {{medline-title
* {{medline-title
|title=Prospective association between adherence to the MIND diet and subjective memory complaints in the French NutriNet-Santé cohort.
|title=The integration of epigenetics and genetics in nutrition research for CVD risk factors.
|date=04.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27919301
|full-text-url=https://sci-hub.do/10.1007/s00415-019-09218-y
|full-text-url=https://sci-hub.do/10.1017/S0029665116000823
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}}
* {{medline-title
* {{medline-title
|title=Relationship between physical and cognitive performance in community dwelling, ethnically diverse older adults: a cross-sectional study.
|title=Latent structure of cognitive performance in the adult children study.
|date=2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30643695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27868476
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327882
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438781
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}}
* {{medline-title
* {{medline-title
|title=Associations of Hearing Loss and Depressive Symptoms With Incident Disability in Older Adults: Health, Aging, and Body Composition Study.
|title=Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review.
|date=14.02.2020
|date=22.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30561511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27875990
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120447
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}}
* {{medline-title
* {{medline-title
|title=Effects of a 12-Week Aerobic Spin Intervention on Resting State Networks in Previously Sedentary Older Adults.
|title=Association of Brain Amyloid-β With Slow Gait in Elderly Individuals Without Dementia: Influence of Cognition and Apolipoprotein E ε4 Genotype.
|date=2018
|date=01.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30542314
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27842173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735996
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}}
* {{medline-title
* {{medline-title
|title=Erythrocyte sedimentation rate as an independent prognostic marker for mortality: a prospective population-based cohort study.
|title=Effect of the Interplay Between Genetic and Behavioral Risks on Survival After Age 75.
|date=03.2019
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537394
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27806189
|full-text-url=https://sci-hub.do/10.1111/joim.12853
|full-text-url=https://sci-hub.do/10.1111/jgs.14391
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}}
* {{medline-title
* {{medline-title
|title=Moderate Aerobic Training Decreases Blood Pressure but No Other Cardiovascular Risk Factors in Hypertensive Overweight/Obese Elderly Patients.
|title=Homocysteine and Real-Space Navigation Performance among Non-Demented Older Adults.
|date=01-12.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30450368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27802238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236479
|full-text-url=https://sci-hub.do/10.3233/JAD-160667
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}}
* {{medline-title
* {{medline-title
|title=The burden of common variable immunodeficiency disorders: a retrospective analysis of the European Society for Immunodeficiency (ESID) registry data.
|title=Obesity, Apolipoprotein E ε4, and Difficulties in Activities of Daily Living Among Older Adults: a 6-Year Follow-up Study.
|date=12.11.2018
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30419968
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27738971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233554
|full-text-url=https://sci-hub.do/10.1007/s12160-016-9848-y
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}}
* {{medline-title
* {{medline-title
|title=Survival after non-traumatic spinal cord injury: evidence from a population-based rehabilitation cohort in Switzerland.
|title=Comparison of Gait Parameters for Predicting Cognitive Decline: The Mayo Clinic Study of Aging.
|date=04.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30413804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27662317
|full-text-url=https://sci-hub.do/10.1038/s41393-018-0212-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378311
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* {{medline-title
* {{medline-title
|title=Is there a correlation between an eGFR slope measured over a 5-year period and incident cardiovascular events in the following 5 years among a Flemish general practice population: a retrospective cohort study.
|title=The [[APOE]] paradox: do attentional control differences in mid-adulthood reflect risk of late-life cognitive decline.
|date=12.11.2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30420350
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27661410
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252738
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.08.015
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* {{medline-title
* {{medline-title
|title=Biphasic concentration-dependent interaction between imidacloprid and dietary phytochemicals in honey bees (Apis mellifera).
|title=Relative effect of [[APOE]] ε4 on neuroimaging biomarker changes across the lifespan.
|date=2018
|date=18.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30383869
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27683850
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211726
|full-text-url=https://sci-hub.do/10.1212/WNL.0000000000003234
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}}
* {{medline-title
* {{medline-title
|title=Heart rate variability in middle-aged sprint and endurance athletes.
|title=The Effects of an [[APOE]] Promoter Polymorphism on Human White Matter Connectivity during Non-Demented Aging.
|date=01.06.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389479
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27636845
|full-text-url=https://sci-hub.do/10.1016/j.physbeh.2018.10.018
|full-text-url=https://sci-hub.do/10.3233/JAD-160447
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* {{medline-title
* {{medline-title
|title=Serum cystatin C, impaired kidney function, and geriatric depressive symptoms among older people living in a rural area: a population-based study.
|title=Dopamine Receptor Genes Modulate Associative Memory in Old Age.
|date=06.11.2018
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400830
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27647283
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219054
|full-text-url=https://sci-hub.do/10.1162/jocn_a_01048
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* {{medline-title
* {{medline-title
|title=Office and Ambulatory Heart Rate as Predictors of Age-Related Kidney Function Decline.
|title=Precuneus degeneration in nondemented elderly individuals with [[APOE]] ɛ4: Evidence from structural and functional MRI analyses.
|date=09.2018
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27593520
|full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.118.11594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866889
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* {{medline-title
* {{medline-title
|title=Aging Alters the Relative Contributions of the Sympathetic and Parasympathetic Nervous System to Blood Pressure Control in Women.
|title=Effects of the [[APOE]] ε4 allele and education on cognitive function in Japanese centenarians.
|date=11.2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27558117
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}}
}}
* {{medline-title
* {{medline-title
|title=Association between treatment of superficial bladder cancer and 10-year mortality in older adults with multiple chronic conditions.
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
|date=01.12.2018
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30289971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680
|full-text-url=https://sci-hub.do/10.1002/cncr.31705
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}}
* {{medline-title
* {{medline-title
|title=Conjoint differences in inhibitory control and processing speed in childhood to older adult cohorts: Discriminant functions from a Go/No-Go task.
|title=Mixed brain lesions mediate the association between cardiovascular risk burden and cognitive decline in old age: A population-based study.
|date=11.2018
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30284853
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27521789
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}}
* {{medline-title
* {{medline-title
|title=Heart Rate Fragmentation as a Novel Biomarker of Adverse Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis.
|title=Assessment of the contribution of [[APOE]] gene variants to metabolic phenotypes associated with familial longevity at middle age.
|date=2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30233384
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27540764
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}}
* {{medline-title
* {{medline-title
|title=Partial nephrectomy is not associated with an overall survival advantage over radical nephrectomy in elderly patients with stage Ib-II renal masses: An analysis of the national cancer data base.
|title=Neuritic and Diffuse Plaque Associations with Memory in Non-Cognitively Impaired Elderly.
|date=01.10.2018
|date=14.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30207380
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27540968
|full-text-url=https://sci-hub.do/10.1002/cncr.31582
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}}
* {{medline-title
* {{medline-title
|title=Uraemia-induced immune senescence and clinical outcomes in chronic kidney disease patients.
|title=White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration.
|date=01.04.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30202981
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27489875
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}}
* {{medline-title
* {{medline-title
|title=Cognitive functioning transitions, health expectancies, and inequalities among elderly people in China: A nationwide longitudinal study.
|title=[[APOE]] ε4 allele modifies the association of lead exposure with age-related cognitive decline in older individuals.
|date=12.2018
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206988
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27474937
|full-text-url=https://sci-hub.do/10.1002/gps.4966
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}}
* {{medline-title
* {{medline-title
|title=Diurnal rhythms of heart and respiratory rates in donkeys of different age groups during the cold-dry and hot-dry seasons in a tropical savannah.
|title=[[APOE]] genotype and stress response - a mini review.
|date=09.2018
|date=25.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27457486
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}}
}}
* {{medline-title
* {{medline-title
|title=Absolute 10-year risk of dementia by age, sex and [i]APOE[/i] genotype: a population-based cohort study.
|title=An Alzheimer's Disease Genetic Risk Score Predicts Longitudinal Thinning of Hippocampal Complex Subregions in Healthy Older Adults.
|date=04.09.2018
|date=05-06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30181149
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27482534
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}}
}}
* {{medline-title
* {{medline-title
|title=Testosterone Levels and Type 2 Diabetes-No Correlation with Age, Differential Predictive Value in Men and Women.
|title=Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort.
|date=20.08.2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30127326
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27436677
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}}
}}
* {{medline-title
* {{medline-title
|title=Vegetable Diversity, Injurious Falls, and Fracture Risk in Older Women: A Prospective Cohort Study.
|title=FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging.
|date=13.08.2018
|date=14.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30104494
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27447426
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}}
}}
* {{medline-title
* {{medline-title
|title=Evidence of oxidative stress-induced senescence in mature, post-mature and pathological human placentas.
|title=Affect of [[APOE]] on information processing speed in non-demented elderly population: a preliminary structural MRI study.
|date=08.2018
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055665
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27444731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083404
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}}
* {{medline-title
* {{medline-title
|title=Enoch Senior's College for Korean Immigrant Seniors: Quality of Life Effects.
|title=Lipid Profiles and [[APOE]]4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy.
|date=09.2018
|date=15.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30058523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27448678
|full-text-url=https://sci-hub.do/10.1017/S0714980818000211
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}}
* {{medline-title
* {{medline-title
|title=Non-AIDS Mortality Is Higher Among Successfully Treated People Living with HIV Compared with Matched HIV-Negative Control Persons: A 15-Year Follow-Up Cohort Study in Sweden.
|title=The effect of β-amyloid positivity on cerebral metabolism in cognitively normal seniors.
|date=08.2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30067408
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27445158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088250
|full-text-url=https://sci-hub.do/10.1016/j.jalz.2016.06.003
}}
}}
* {{medline-title
* {{medline-title
|title=Gain without pain: Glucose promotes cognitive engagement and protects positive affect in older adults.
|title=The Effect of the [[APOE]] Genotype on Individual BrainAGE in Normal Aging, Mild Cognitive Impairment, and Alzheimer's Disease.
|date=08.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29999390
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|full-text-url=https://sci-hub.do/10.1037/pag0000270
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}}
* {{medline-title
* {{medline-title
|title=Ten-year changes in ambulatory blood pressure: The prognostic value of ambulatory pulse pressure.
|title=Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice.
|date=09.2018
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29981188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27406263
|full-text-url=https://sci-hub.do/10.1111/jch.13344
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}}
* {{medline-title
* {{medline-title
|title=Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts.
|title=Gray matter maturation and cognition in children with different [[APOE]] ε genotypes.
|date=15.02.2019
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}}
* {{medline-title
* {{medline-title
|title=Supplementation with resveratrol as Polygonum cuspidatum Sieb. et Zucc. extract induces changes in the excretion of urinary markers associated to aging in rats.
|title=The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and [[APOE]].
|date=09.2018
|date=02.08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29959053
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27371485
|full-text-url=https://sci-hub.do/10.1016/j.fitote.2018.06.022
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}}
* {{medline-title
* {{medline-title
|title=Subjective cognitive decline and risk of MCI: The Mayo Clinic Study of Aging.
|title=Impact of Personality on Cognitive Aging: A Prospective Cohort Study.
|date=24.07.2018
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29959257
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27346168
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|full-text-url=https://sci-hub.do/10.1017/S1355617716000527
}}
}}
* {{medline-title
* {{medline-title
|title=Maternal gene [i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes.
|title=Changes in Frailty Predict Changes in Cognition in Older Men: The Honolulu-Asia Aging Study.
|date=18.11.2018
|date=15.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27314525
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}}
* {{medline-title
* {{medline-title
|title=Progression of frailty and prevalence of osteoporosis in a community cohort of older women-a 10-year longitudinal study.
|title=[[APOE]] and aging-related cognitive change in a longitudinal cohort of men.
|date=10.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29947868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27318143
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|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.04.024
}}
}}
* {{medline-title
* {{medline-title
|title=Higher spermidine intake is linked to lower mortality: a prospective population-based study.
|title=Braak stage and trajectory of cognitive decline in noncognitively impaired elders.
|date=01.08.2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955838
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27255819
|full-text-url=https://sci-hub.do/10.1093/ajcn/nqy102
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894536
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}}
* {{medline-title
* {{medline-title
|title=Childhood IQ and mortality during 53 years' follow-up of Swedish men and women.
|title=Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models.
|date=10.2018
|date=30.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29925669
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27265785
|full-text-url=https://sci-hub.do/10.1136/jech-2018-210675
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}}
* {{medline-title
* {{medline-title
|title=Age-related changes in cardiac electrophysiology and calcium handling in response to sympathetic nerve stimulation.
|title=Global hypoxia induced impairment in learning and spatial memory is associated with precocious hippocampal aging.
|date=09.2018
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29938794
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27246251
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|full-text-url=https://sci-hub.do/10.1016/j.nlm.2016.05.011
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}}
* {{medline-title
* {{medline-title
|title=Physical activity and sedentary behavior in relation to mortality among renal cell cancer survivors.
|title=Selective familiarity deficits in otherwise cognitively intact aging individuals with genetic risk for Alzheimer's disease.
|date=2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29894512
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27239534
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879663
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}}
* {{medline-title
* {{medline-title
|title=Increased CAIDE dementia risk, cognition, CSF biomarkers, and vascular burden in healthy adults.
|title=Blood glucose levels and cortical thinning in cognitively normal, middle-aged adults.
|date=17.07.2018
|date=15.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27206882
|full-text-url=https://sci-hub.do/10.1212/WNL.0000000000005824
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876973
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}}
* {{medline-title
* {{medline-title
|title=Associations Between Heart Rate Recovery Dynamics With Estradiol Levels in 20 to 60 Year-Old Sedentary Women.
|title=Relationship between [[APOE]] Genotype and Structural MRI Measures throughout Adulthood in the Study of Health in Pomerania Population-Based Cohort.
|date=2018
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29867572
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27173368
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962759
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154957
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}}
* {{medline-title
* {{medline-title
|title=Prognostic value of age adjusted segment involvement score as measured by coronary computed tomography: a potential marker of vascular age.
|title=Waist circumference is correlated with poorer cognition in elderly type 2 diabetes women.
|date=11.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797058
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27149905
|full-text-url=https://sci-hub.do/10.1007/s00380-018-1188-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753411
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}}
* {{medline-title
* {{medline-title
|title=The Acute Effects of Age and Particulate Matter Exposure on Heart Rate and Heart Rate Variability in Mice.
|title=Risk-reducing Apolipoprotein E and Clusterin genotypes protect against the consequences of poor vascular health on executive function performance and change in nondemented older adults.
|date=12.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774517
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27143425
|full-text-url=https://sci-hub.do/10.1007/s12012-018-9461-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857019
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}}
* {{medline-title
* {{medline-title
|title=Neuroticism predicts all-cause mortality over 19-years: The moderating effects on functional status, and the angiotensin-converting enzyme.
|title=Alzheimer disease genetic risk factor [[APOE]] e4 and cognitive abilities in 111,739 UK Biobank participants.
|date=07.2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29764603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27103599
|full-text-url=https://sci-hub.do/10.1016/j.jpsychores.2018.04.013
|full-text-url=https://sci-hub.do/10.1093/ageing/afw068
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}}
* {{medline-title
* {{medline-title
|title=Anxiety and 10-Year Risk of Incident Dementia-An Association Shaped by Depressive Symptoms: Results of the Prospective Three-City Study.
|title=[[APOE]]4 Induces Site-Specific Tau Phosphorylation Through Calpain-[[CDK5]] Signaling Pathway in EFAD-Tg Mice.
|date=2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719498
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27087442
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|full-text-url=https://sci-hub.do/10.2174/1567205013666160415154550
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}}
* {{medline-title
* {{medline-title
|title=Delirium as a predictor of mortality in US Medicare beneficiaries discharged from the emergency department: a national claims-level analysis up to 12 months.
|title=Cardiometabolic risk factors predict cerebrovascular health in older adults: results from the Brain in Motion study.
|date=05.05.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730630
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27117804
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* {{medline-title
* {{medline-title
|title=Prognostic value of cardiac troponin I assay in hospitalized elderly patients.
|title=Dementia Risk and Protective Factors Differ in the Context of Memory Trajectory Groups.
|date=02.2019
|date=12.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27079709
|full-text-url=https://sci-hub.do/10.1007/s40520-018-0965-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884159
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* {{medline-title
* {{medline-title
|title=The influence of participation on mortality in very old age among community-living people in Sweden.
|title=Variants near CHRNA3/5 and [[APOE]] have age- and sex-related effects on human lifespan.
|date=02.2019
|date=31.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29679295
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27029810
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}}
* {{medline-title
* {{medline-title
|title=Mediterranean diet and hip fracture incidence among older adults: the CHANCES project.
|title=Age, [[APOE]] and sex: Triad of risk of Alzheimer's disease.
|date=07.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656347
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26969397
|full-text-url=https://sci-hub.do/10.1007/s00198-018-4517-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905558
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* {{medline-title
* {{medline-title
|title=Depression in type 1 diabetes and risk of dementia.
|title=Occupational cognitive requirements and late-life cognitive aging.
|date=07.2019
|date=12.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29634288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26984944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179940
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* {{medline-title
* {{medline-title
|title=Testosterone and All-Cause Mortality in Older Men: The Role of Metabolic Syndrome.
|title=Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease.
|date=01.04.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577108
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26962052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848820
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* {{medline-title
* {{medline-title
|title=Arterial stiffening is a heritable trait associated with arterial dilation but not wall thickening: a longitudinal study in the twins UK cohort.
|title=Genetic landscape of [[APOE]] in human longevity revealed by high-throughput sequencing.
|date=21.06.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590330
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26930295
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012080
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* {{medline-title
* {{medline-title
|title=Pulmonary Hypertension in Central Australia: A Community-Based Cohort Study.
|title=No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.
|date=04.2019
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29599030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946122
|full-text-url=https://sci-hub.do/10.1016/j.hlc.2018.02.020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709
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* {{medline-title
* {{medline-title
|title=The application of the palliative prognostic index in predicting the life expectancy of patients in palliative care: a systematic review and meta-analysis.
|title=Lack of neural compensatory mechanisms of [[BDNF]] val66met met carriers and [[APOE]] E4 carriers in healthy aging, mild cognitive impairment, and Alzheimer's disease.
|date=12.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29572610
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26923413
|full-text-url=https://sci-hub.do/10.1007/s40520-018-0928-7
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.12.004
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* {{medline-title
* {{medline-title
|title=Weight loss in men in late life and bone strength and microarchitecture: a prospective study.
|title=Novel loci and pathways significantly associated with longevity.
|date=07.2018
|date=25.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29572622
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912274
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035779
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766491
}}
}}
* {{medline-title
* {{medline-title
|title=[The life span of red blood cell in patients with severe/very severe aplastic anemia].
|title=White matter hyperintensities and imaging patterns of brain ageing in the general population.
|date=14.02.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29562449
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912649
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006227
}}
}}
* {{medline-title
* {{medline-title
|title=Dairy product consumption and its association with metabolic disturbance in a prospective study of urban adults.
|title=Characterization of Amyloid-β Deposits in Bovine Brains.
|date=03.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29553032
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26890772
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927890
}}
}}
* {{medline-title
* {{medline-title
|title=Factors associated with polypharmacy in primary care: a cross-sectional analysis of data from The English Longitudinal Study of Ageing (ELSA).
|title=The role of [[APOE]] in cerebrovascular dysfunction.
|date=14.03.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26884068
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837016
}}
}}
* {{medline-title
* {{medline-title
|title=Do Patients Live Longer After THA and Is the Relative Survival Diagnosis-specific?
|title=Decreased Inter-Hemispheric Functional Connectivity in Cognitively Intact Elderly [[APOE]] ɛ4 Carriers: A Preliminary Study.
|date=06.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29489471
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26836191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263594
|full-text-url=https://sci-hub.do/10.3233/JAD-150989
}}
}}
* {{medline-title
* {{medline-title
|title=The relationship between excessive daytime sleepiness, disability, and mortality, and implications for life expectancy.
|title=[[APOE]] ε4 associated with preserved executive function performance and maintenance of temporal and cingulate brain volumes in younger adults.
|date=03.2018
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26843007
|full-text-url=https://sci-hub.do/10.1016/j.sleep.2017.11.1132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972704
}}
}}
* {{medline-title
* {{medline-title
|title=Long-Term Atherosclerotic Vascular Disease Risk and Prognosis in Elderly Women With Abdominal Aortic Calcification on Lateral Spine Images Captured During Bone Density Testing: A Prospective Study.
|title=[GENETIC AND EPIGENETIC DETERMINANTS OF ALZHEIMER'S DISEASE].
|date=06.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29443425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26856092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415911
 
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in with-the-rule and oblique corneal astigmatism.
|title=Olfactory memory in the old and very old: relations to episodic and semantic memory and [[APOE]] genotype.
|date=09.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369508
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26827650
|full-text-url=https://sci-hub.do/10.1111/aos.13683
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.11.012
}}
}}
* {{medline-title
* {{medline-title
|title=Ageing perceptions and non-adherence to aromatase inhibitors among breast cancer survivors.
|title=The [[APOE]] epsilon 4 polymorphism does not predict late onset depression: the Three-City Study.
|date=03.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29329697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26785975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803454
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.12.018
}}
}}
* {{medline-title
* {{medline-title
|title=The prospective and concurrent effect of exercise on health related quality of life in older adults over a 3 year period.
|title=High homocysteine and epistasis between [[MTHFR]] and [[APOE]]: association with cognitive performance in the elderly.
|date=16.01.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338743
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26774227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771011
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.01.005
}}
}}
* {{medline-title
* {{medline-title
|title=Utility of Time and Frequency Domain Parameters of Heart Rate Variability in the Context of Autonomic Disorders Characterized by Orthostatic Dysfunction.
|title=The Relationship Between Plasma Aβ Levels, Cognitive Function and Brain Volumetrics: Sydney Memory and Ageing Study.
|date=03.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29342011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26679856
|full-text-url=https://sci-hub.do/10.1097/WNP.0000000000000452
|full-text-url=https://sci-hub.do/10.2174/1567205013666151218150202
}}
}}
* {{medline-title
* {{medline-title
|title=Association Between Heart Rate and Subclinical Cerebrovascular Disease in the Elderly.
|title=Braak staging, plaque pathology, and [[APOE]] status in elderly persons without cognitive impairment.
|date=02.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29284731
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26686670
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870891
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687022
}}
}}
* {{medline-title
* {{medline-title
|title=An additive effect of leading role in the organization between social participation and dementia onset among Japanese older adults: the AGES cohort study.
|title=Biomarkers of cholesterol homeostasis in a clinical laboratory database sample comprising 667,718 patients.
|date=29.12.2017
|date=11-12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29284406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26687702
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747184
|full-text-url=https://sci-hub.do/10.1016/j.jacl.2015.08.003
}}
}}
* {{medline-title
* {{medline-title
|title=Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions.
|title=Genetic factors and epigenetic mechanisms of longevity: current perspectives.
|date=04.01.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249653
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26639084
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756112
|full-text-url=https://sci-hub.do/10.2217/epi.15.80
}}
}}
* {{medline-title
* {{medline-title
|title=Metabolites Associated With Risk of Developing Mobility Disability in the Health, Aging and Body Composition Study.
|title=Subjective Memory Complaints in [[APOE]]ɛ4 Carriers are Associated with High Amyloid-β Burden.
|date=01.01.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29186400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26639956
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298186
|full-text-url=https://sci-hub.do/10.3233/JAD-150446
}}
}}
* {{medline-title
* {{medline-title
|title=Which Sleep Health Characteristics Predict All-Cause Mortality in Older Men? An Application of Flexible Multivariable Approaches.
|title=Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: the modulating effects of older age and disease severity.
|date=01.01.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29165696
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26617462
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659385
}}
}}
* {{medline-title
* {{medline-title
|title=Social isolation, health literacy, and mortality risk: Findings from the English Longitudinal Study of Ageing.
|title=Individual estimates of age at detectable amyloid onset for risk factor assessment.
|date=02.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172607
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26588863
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841700
}}
* {{medline-title
|title=Influence of amyloid and [[APOE]] on cognitive performance in a late middle-aged cohort.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26602629
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850495
}}
* {{medline-title
|title=Gene-Environment Interplay in Physical, Psychological, and Cognitive Domains in Mid to Late Adulthood: Is [[APOE]] a Variability Gene?
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26538244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858319
}}
}}
* {{medline-title
* {{medline-title
|title=Bone Loss at the Hip and Subsequent Mortality in Older Men: The Osteoporotic Fractures in Men (MrOS) Study.
|title=Predictors of Cognitive and Functional Decline in Patients With Alzheimer Disease Dementia From Brazil.
|date=08.2017
|date=07-09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29124252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26523709
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673261
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000117
}}
}}
* {{medline-title
* {{medline-title
|title=Thyroid status and mortality in nonagenarians from long-lived families and the general population.
|title=[[APOE]] Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction.
|date=25.10.2017
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29070732
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26512759
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680564
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626092
}}
}}
* {{medline-title
* {{medline-title
|title=Frailty index as a predictor of mortality: a systematic review and meta-analysis.
|title=Association of [[APOE]] with tau-tangle pathology with and without β-amyloid.
|date=01.03.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29040347
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26481403
|full-text-url=https://sci-hub.do/10.1093/ageing/afx162
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716785
}}
}}
* {{medline-title
* {{medline-title
|title=Trajectories of IGF-I Predict Mortality in Older Adults: The Cardiovascular Health Study.
|title=[[APOE]] Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration.
|date=14.06.2018
|date=07.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28977343
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26446211
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605380
}}
}}
* {{medline-title
* {{medline-title
|title=Is orthostatic hypotension more common in individuals with atrial fibrillation?-Findings from The Irish Longitudinal Study on Ageing (TILDA).
|title=The Role of Alzheimer's and Cerebrovascular Pathology in Mediating the Effects of Age, Race, and Apolipoprotein E Genotype on Dementia Severity in Pathologically-Confirmed Alzheimer's Disease.
|date=01.11.2017
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28985288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26444761
|full-text-url=https://sci-hub.do/10.1093/ageing/afx096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858176
}}
}}
* {{medline-title
* {{medline-title
|title=Subjective life expectancy is a risk factor for perceived health status and mortality.
|title=[SOME RESULTS OF MOLECULAR GENETIC RESEARCHES OF AGING AND LONGEVITY].
|date=02.10.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28969645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26390605
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625600
 
}}
}}
* {{medline-title
* {{medline-title
|title=The effects of dexmedetomidine preconditioning on aged rat heart of ischaemia reperfusion injury.
|title=Ankle-Brachial Index but Neither Intima Media Thickness Nor Coronary Artery Calcification is Associated With Mild Cognitive Impairment.
|date=10.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28987955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26401565
|full-text-url=https://sci-hub.do/10.1016/j.rvsc.2017.09.028
|full-text-url=https://sci-hub.do/10.3233/JAD-150218
}}
}}
* {{medline-title
* {{medline-title
|title=Diabetes and Deficits in Cortical Bone Density, Microarchitecture, and Bone Size: Framingham [[HR]]-pQCT Study.
|title=No difference in paired associative stimulation induced cortical neuroplasticity between patients with mild cognitive impairment and elderly controls.
|date=01.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28929525
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26394910
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771832
|full-text-url=https://sci-hub.do/10.1016/j.clinph.2015.08.010
}}
}}
* {{medline-title
* {{medline-title
|title=Gender differences in longevity in free-living older adults who eat-with-others: a prospective study in Taiwan.
|title=Comparison of ApoE-related brain connectivity differences in early MCI and normal aging populations: an fMRI study.
|date=18.09.2017
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928182
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26409470
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623554
|full-text-url=https://sci-hub.do/10.1007/s11682-015-9451-z
}}
}}
* {{medline-title
* {{medline-title
|title=Decline in effort capacity with age: Echocardiographic stress analysis in the elderly.
|title=Effects of [[APOE]] rs429358, rs7412 and [[GSTM1]]/[[GSTT1]] Polymorphism on Plasma and Erythrocyte Antioxidant Parameters and Cognition in Old Chinese Adults.
|date=12.2017
|date=24.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28921674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26404360
|full-text-url=https://sci-hub.do/10.1111/echo.13709
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632411
}}
}}
* {{medline-title
* {{medline-title
|title=Impaired disengagement of attention and its relationship to emotional distress in infants at high-risk for autism spectrum disorder.
|title=Does apolipoprotein E genotype influence cognition in middle-aged individuals?
|date=06.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28914144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26402402
|full-text-url=https://sci-hub.do/10.1080/13803395.2017.1372368
|full-text-url=https://sci-hub.do/10.1097/WCO.0000000000000262
}}
}}
* {{medline-title
* {{medline-title
|title=Statins for Primary Prevention of Cardiovascular Events and Mortality in Older Men.
|title=Diabetes is Associated with Worse Executive Function in Both Eastern and Western Populations: Shanghai Aging Study and Mayo Clinic Study of Aging.
|date=11.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28892121
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26402765
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681374
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617674
}}
}}
* {{medline-title
* {{medline-title
|title=Galectin-3 and risk of ischaemic stroke: Reasons for Geographic and Racial Differences in Stroke cohort.
|title=[[APOE]] Affects the Volume and Shape of the Amygdala and the Hippocampus in Mild Cognitive Impairment and Alzheimer's Disease: Age Matters.
|date=12.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28872212
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26401700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008611
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479937
}}
}}
* {{medline-title
* {{medline-title
|title=Sleep duration, mortality and the influence of age.
|title=[[APOE]]-by-sex interactions on brain structure and metabolism in healthy elderly controls.
|date=10.2017
|date=29.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28856478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26397226
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694943
}}
}}
* {{medline-title
* {{medline-title
|title=Comparison of yoga and walking-exercise on cardiac time intervals as a measure of cardiac function in elderly with increased pulse pressure.
|title=[[APOE]] Genotype Affects Cognitive Training Response in Healthy Shanghai Community-Dwelling Elderly Individuals.
|date=07-08.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822516
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26401781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560911
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799000
}}
}}
* {{medline-title
* {{medline-title
|title=Dietary acid load and renal function have varying effects on blood acid-base status and exercise performance across age and sex.
|title=Association of White Matter Integrity and Cognitive Functions in Chinese Non-Demented Elderly with the [[APOE]] ɛ4 Allele.
|date=12.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26402101
|full-text-url=https://sci-hub.do/10.1139/apnm-2017-0279
|full-text-url=https://sci-hub.do/10.3233/JAD-150357
}}
}}
* {{medline-title
* {{medline-title
|title=Elite Distance Runners: A 45-Year Follow-up.
|title=Vascular Health and Genetic Risk Affect Mild Cognitive Impairment Status and 4-Year Stability: Evidence From the Victoria Longitudinal Study.
|date=01.2018
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26362601
|full-text-url=https://sci-hub.do/10.1249/MSS.0000000000001407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067948
}}
}}
* {{medline-title
* {{medline-title
|title=Short-term water-based aerobic training promotes improvements in aerobic conditioning parameters of mature women.
|title=Apolipoprotein E and Clusterin can magnify effects of personality vulnerability on declarative memory performance in non-demented older adults.
|date=08.2017
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28779920
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26343804
|full-text-url=https://sci-hub.do/10.1016/j.ctcp.2017.06.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826141
}}
}}
==APOE==
* {{medline-title
* {{medline-title
|title=Polygenic risk score of longevity predicts longer survival across an age-continuum.
|title=Examining the association between Apolipoprotein E ([[APOE]]) and self-reported sleep disturbances in non-demented older adults.
|date=20.11.2020
|date=08.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33216869
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26314507
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa289
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598304
}}
}}
* {{medline-title
* {{medline-title
|title=Association Between [[APOE]] Alleles and Change of Neuropsychological Tests in the Long Life Family Study.
|title=G×E Interaction Influences Trajectories of Hand Grip Strength.
|date=17.11.2020
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33216038
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26318288
|full-text-url=https://sci-hub.do/10.3233/JAD-201113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720577
}}
}}
* {{medline-title
* {{medline-title
|title=The [[APOE]] gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans.
|title=Effects of [[APOE]] promoter polymorphism on the topological organization of brain structural connectome in nondemented elderly.
|date=20.11.2020
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33215813
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26314833
|full-text-url=https://sci-hub.do/10.1002/alz.12230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715757
}}
}}
* {{medline-title
* {{medline-title
|title=Homozygosity in the [i][[APOE]][/i] 3 Polymorphism Is Associated With Less Depression and Higher Serum Low-Density Lipoprotein in Chinese Elderly Schizophrenics.
|title=Interactive effects of physical activity and [[APOE]]-ε4 on white matter tract diffusivity in healthy elders.
|date=2020
|date=01.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33178131
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26265157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746115
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of apolipoprotein E polymorphism on cognition and brain in the Cambridge Centre for Ageing and Neuroscience cohort.
|title=Brain Amyloid Deposition and Longitudinal Cognitive Decline in Nondemented Older Subjects: Results from a Multi-Ethnic Population.
|date=01-12.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33088920
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26221954
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519341
}}
* {{medline-title
|title=DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor ([[BDNF]]) and oxytocin receptor ([[OXTR]]) genes are associated with anxiety/depression in older women.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26175754
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485183
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}}
* {{medline-title
* {{medline-title
|title=Cardiovascular risk factors and [[APOE]]-ε4 status affect memory functioning in aging via changes to temporal stem diffusion.
|title=Longitudinal cognitive decline in the AIBL cohort: The role of [[APOE]] ε4 status.
|date=18.10.2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33070365
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|full-text-url=https://sci-hub.do/10.1002/jnr.24734
|full-text-url=https://sci-hub.do/10.1016/j.neuropsychologia.2015.06.008
}}
}}
* {{medline-title
* {{medline-title
|title=[[APOE]] [i]ε[/i]4 and resting-state functional connectivity in racially/ethnically diverse older adults.
|title=Anterior cingulate cortex mediates the relationship between O3PUFAs and executive functions in [[APOE]] e4 carriers.
|date=2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32999914
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}}
* {{medline-title
* {{medline-title
|title=Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study.
|title=Current versus lifetime depression, [[APOE]] variation, and their interaction on cognitive performance in younger and older adults.
|date=13.11.2020
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32886741
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26035038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662159
|full-text-url=https://sci-hub.do/10.1097/PSY.0000000000000190
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}}
* {{medline-title
* {{medline-title
|title=When Culture Influences Genes: Positive Age Beliefs Amplify the Cognitive-Aging Benefit of [[APOE]] ε2.
|title=Aging, Practice Effects, and Genetic Risk in the Wisconsin Registry for Alzheimer's Prevention.
|date=14.09.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32835364
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26012360
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}}
* {{medline-title
* {{medline-title
|title=Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study.
|title=Glucose Dysregulation Interacts With [[APOE]]-∊4 to Potentiate Temporoparietal Cortical Thinning.
|date=08.2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32817639
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}}
* {{medline-title
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|title=Estimating the potential for dementia prevention through modifiable risk factors elimination in the real-world setting: a population-based study.
|title=Spatial pattern separation differences in older adult carriers and non-carriers for the apolipoprotein E epsilon 4 allele.
|date=07.08.2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32767997
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}}
* {{medline-title
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|title=Machine learning-based estimation of cognitive performance using regional brain MRI markers: the Northern Manhattan Study.
|title=GWAS and Meta-Analysis in Aging/Longevity.
|date=01.08.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32740887
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|full-text-url=https://sci-hub.do/10.1007/s11682-020-00325-3
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}}
* {{medline-title
* {{medline-title
|title=Effects of an [[APOE]] Promoter Polymorphism on Fronto-Parietal Functional Connectivity During Nondemented Aging.
|title=Odor identification and Alzheimer disease biomarkers in clinically normal elderly.
|date=2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32694990
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25934852
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* {{medline-title
* {{medline-title
|title=The relationship of parental longevity with the aging brain-results from UK Biobank.
|title=Aging, Alzheimer's, and [[APOE]] genotype influence the expression and neuronal distribution patterns of microtubule motor protein dynactin-P50.
|date=10.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32671621
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25859183
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525531
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* {{medline-title
* {{medline-title
|title=Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation.
|title=Interaction of Cigarette Smoking History With [[APOE]] Genotype and Age on Amyloid Level, Glucose Metabolism, and Neurocognition in Cognitively Normal Elders.
|date=30.06.2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32610143
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* {{medline-title
* {{medline-title
|title=Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease.
|title=[[APOE]]4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice.
|date=2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32474467
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* {{medline-title
* {{medline-title
|title=Effects of sex, age, and apolipoprotein E genotype on hippocampal parenchymal fraction in cognitively normal older adults.
|title=[[APOE]] ε4 Genotype and the Risk for Subjective Cognitive Impairment in Elderly Persons.
|date=30.07.2020
|date=Fall.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32416384
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|full-text-url=https://sci-hub.do/10.1016/j.pscychresns.2020.111107
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* {{medline-title
|title=Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of Aging.
|date=07.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25788555
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* {{medline-title
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|title=Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO).
|title=The identification of cognitive subtypes in Alzheimer's disease dementia using latent class analysis.
|date=05.05.2020
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* {{medline-title
* {{medline-title
|title=Apolipoprotein E and Health in Older Men: The Concord Health and Ageing in Men Project.
|title=Age, Sex, and [[APOE]] ε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span.
|date=25.09.2020
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32342099
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25775353
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa105
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* {{medline-title
* {{medline-title
|title=CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease.
|title=Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults.
|date=07.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32305782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25738563
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.03.008
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|title=Association of Cardiovascular Risk Factors with Cerebral Perfusion in Whites and African Americans.
|title=Bone mineral density, adiposity, and cognitive functions.
|date=2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25741279
|full-text-url=https://sci-hub.do/10.3233/JAD-190360
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* {{medline-title
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|title=Alzheimer's Risk Factors Age, [[APOE]] Genotype, and Sex Drive Distinct Molecular Pathways.
|title=Buccal cell cytokeratin 14 identifies mild cognitive impairment and Alzheimer' s disease in the AIBL study of aging.
|date=03.06.2020
|date=2015
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25731627
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|full-text-url=https://sci-hub.do/10.2174/1567205012666150302154650
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|title=Less agreeable, better preserved? A PET amyloid and MRI study in a community-based cohort.
|title=Traumatic brain injury and late-life dementia.
|date=05.2020
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|full-text-url=https://sci-hub.do/10.1016/B978-0-444-63521-1.00044-3
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* {{medline-title
* {{medline-title
|title=Physical Activity as Moderator of the Association Between [[APOE]] and Cognitive Decline in Older Adults: Results from Three Longitudinal Cohort Studies.
|title=Are the effects of [[APOE]] ϵ4 on cognitive function in nonclinical populations age- and gender-dependent?
|date=25.09.2020
|date=2015
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* {{medline-title
* {{medline-title
|title=Longitudinal Maintenance of Cognitive Health in Centenarians in the 100-plus Study.
|title=Interactive effect of [[APOE]] genotype and blood pressure on cognitive decline: the PATH through life study.
|date=05.02.2020
|date=2015
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* {{medline-title
* {{medline-title
|title=Interaction of [[APOE]], cerebral blood flow, and cortical thickness in the entorhinal cortex predicts memory decline.
|title=Sex-based memory advantages and cognitive aging: a challenge to the cognitive reserve construct?
|date=04.2020
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|title=Determinants of mesial temporal lobe volume loss in older individuals with preserved cognition: a longitudinal PET amyloid study.
|title=DNA methylation age of blood predicts all-cause mortality in later life.
|date=03.2020
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* {{medline-title
* {{medline-title
|title=Long-term exposure to ambient air pollution, [[APOE]]-ε4 status, and cognitive decline in a cohort of older adults in northern Manhattan.
|title=The effects of an [[APOE]] promoter polymorphism on human cortical morphology during nondemented aging.
|date=03.2020
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* {{medline-title
* {{medline-title
|title=Evidence in support of chromosomal sex influencing plasma based metabolome vs [[APOE]] genotype influencing brain metabolome profile in humanized [[APOE]] male and female mice.
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|date=2020
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* {{medline-title
|title=Innovative Research Design Exploring the Effects of Physical Activity and Genetics on Cognitive Performance in Community-Based Older Adults.
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|title=Buying time: a rationale for examining the use of circadian rhythm and sleep interventions to delay progression of mild cognitive impairment to Alzheimer's disease.
|date=2014
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* {{medline-title
* {{medline-title
|title=[[APOE]] region molecular signatures of Alzheimer's disease across races/ethnicities.
|title=Genetic variants modify the effect of age on [[APOE]] methylation in the Genetics of Lipid Lowering Drugs and Diet Network study.
|date=03.2020
|date=02.2015
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* {{medline-title
* {{medline-title
|title=Varying Effects of [[APOE]] Alleles on Extreme Longevity in European Ethnicities.
|title=Genetic factors associated with longevity: a review of recent findings.
|date=13.11.2019
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31724059
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|title=Prospective Evaluation of Cognitive Health and Related Factors in Elderly at Risk for Developing Alzheimer's Dementia: A Longitudinal Cohort Study.
|title=Telomerase Gene (hTERT) and Survival: Results From Two Swedish Cohorts of Older Adults.
|date=2019
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* {{medline-title
* {{medline-title
|title=Association of Cardiovascular and Alzheimer's Disease Risk Factors with Intracranial Arterial Blood Flow in Whites and African Americans.
|title=Epidemic spreading model to characterize misfolded proteins propagation in aging and associated neurodegenerative disorders.
|date=2019
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* {{medline-title
* {{medline-title
|title=Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease?
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|date=17.04.2020
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* {{medline-title
* {{medline-title
|title=Prospective Memory: Age related change is influenced by [[APOE]] genotype.
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* {{medline-title
* {{medline-title
|title=Education Moderates the Relation Between [[APOE]] ɛ4 and Memory in Nondemented Non-Hispanic Black Older Adults.
|title=Resting-state functional connectivity changes in aging apoE4 and apoE-KO mice.
|date=2019
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|title=Apolipoprotein E ε4 allele effects on longitudinal cognitive trajectories are sex and age dependent.
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* {{medline-title
* {{medline-title
|title=Interactive effect of age and [[APOE]]-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects.
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|title=[[APOE]] modifies the interaction of entorhinal cerebral blood flow and cortical thickness on memory function in cognitively normal older adults.
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|title=When time's arrow doesn't bend: [[APOE]]-ε4 influences episodic memory before old age.
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* {{medline-title
* {{medline-title
|title=Cognitive-Motor Integration Performance Is Affected by Sex, [[APOE]] Status, and Family History of Dementia.
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* {{medline-title
* {{medline-title
|title=Associations among amyloid status, age, and longitudinal regional brain atrophy in cognitively unimpaired older adults.
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* {{medline-title
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|title=Cognitive function and neuropathological outcomes: a forward-looking approach.
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* {{medline-title
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|title=[[APOE]] gene-dependent BOLD responses to a breath-hold across the adult lifespan.
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|title=Medial temporal lobe atrophy and posterior atrophy scales normative values.
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* {{medline-title
* {{medline-title
|title=Vascular burden and [[APOE]] ε4 are associated with white matter microstructural decline in cognitively normal older adults.
|title=Cortical ¹¹C-PIB uptake is associated with age, [[APOE]] genotype, and gender in "healthy aging".
|date=03.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24603945
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601608
|full-text-url=https://sci-hub.do/10.3233/JAD-132783
}}
}}
* {{medline-title
* {{medline-title
|title=Responses to executive demand in young adulthood differ by [[APOE]] genotype.
|title=Prevalence of mild cognitive impairment in an urban community in China: a cross-sectional analysis of the Shanghai Aging Study.
|date=15.03.2019
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472114
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24613707
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2018.11.033
|full-text-url=https://sci-hub.do/10.1016/j.jalz.2013.11.002
}}
}}
* {{medline-title
* {{medline-title
|title=Mild Cognitive Impairment that Does Not Progress to Dementia: A Population-Based Study.
|title=Cognitive and neural signatures of the [[APOE]] E4 allele in mid-aged adults.
|date=02.2019
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24582638
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001126
}}
}}
* {{medline-title
* {{medline-title
|title=Neuropathologic, genetic, and longitudinal cognitive profiles in primary age-related tauopathy (PART) and Alzheimer's disease.
|title=Mitochondrial DNA and traumatic brain injury.
|date=01.2019
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30465754
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24523223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542566
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112718
}}
}}
* {{medline-title
* {{medline-title
|title=Independent associations of [[TOMM40]] and [[APOE]] variants with body mass index.
|title=The [[APOE]] ε4 allele in relation to brain white-matter microstructure in adulthood and aging.
|date=02.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30462377
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24506254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351823
|full-text-url=https://sci-hub.do/10.1111/sjop.12099
}}
* {{medline-title
|title=Stress, race, and [[APOE]]: understanding the interplay of risk factors for changes in cognitive functioning.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24521139
|full-text-url=https://sci-hub.do/10.1080/13607863.2014.880403
}}
}}
* {{medline-title
* {{medline-title
|title=Apolipoprotein E genotype moderates the association between dietary polyunsaturated fat and brain function: an exploration of cerebral glutamate and cognitive performance.
|title=Beta-amyloid associated differential effects of [[APOE]] ε4 on brain metabolism in cognitively normal elderly.
|date=09.2020
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30465491
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24495404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531361
|full-text-url=https://sci-hub.do/10.1016/j.jagp.2013.12.173
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults.
|title=Apolipoprotein E and depressive symptoms: shared or independent routes to age-related cognitive decline?
|date=09.2018
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354979
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24434954
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101979
|full-text-url=https://sci-hub.do/10.1097/PSY.0000000000000030
}}
}}
* {{medline-title
* {{medline-title
|title=The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description.
|title=Interaction of [[APOE]] genotype and testosterone on episodic memory in middle-aged men.
|date=12.2018
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24444806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290855
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980008
}}
}}
* {{medline-title
* {{medline-title
|title=Report: NIA workshop on translating genetic variants associated with longevity into drug targets.
|title=Sydney Memory and Ageing Study: an epidemiological cohort study of brain ageing and dementia.
|date=12.2018
|date=12.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30374935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24423224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294726
|full-text-url=https://sci-hub.do/10.3109/09540261.2013.860890
}}
}}
* {{medline-title
* {{medline-title
|title=Dendritic spine remodeling accompanies Alzheimer's disease pathology and genetic susceptibility in cognitively normal aging.
|title=Basal forebrain atrophy and cortical amyloid deposition in nondemented elderly subjects.
|date=01.2019
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30339964
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24418052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092050
}}
}}
* {{medline-title
* {{medline-title
|title=The ApoE ε4 Isoform: Can the Risk of Diseases be Reduced by Environmental Factors?
|title=Interactive effects of apolipoprotein E4 and diabetes risk on later myelinating white matter regions in neurologically healthy older aged adults.
|date=01.01.2019
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30321297
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24381137
|full-text-url=https://sci-hub.do/10.1093/gerona/gly226
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356251
}}
}}
==HR==
* {{medline-title
* {{medline-title
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|title=Patients with hip fracture and total hip arthroplasty surgery differ in anthropometric, but not cardiovascular screening abnormalities.
|date=08.10.2018
|date=02.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33267795
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713041
}}
}}
* {{medline-title
* {{medline-title
|title=Amygdala subnuclei and healthy cognitive aging.
|title=Clinical Role of Lung Ultrasound for the Diagnosis and Prognosis of Coronavirus Disease Pneumonia in Elderly Patients: A Pivotal Study.
|date=01.2019
|date=03.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30291764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33271558
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865708
|full-text-url=https://sci-hub.do/10.1159/000512209
}}
}}
* {{medline-title
* {{medline-title
|title=[[APOE]] ɛ4, rs405509, and rs440446 promoter and intron-1 polymorphisms and dementia risk in a cohort of elderly Finns-Helsinki Birth Cohort Study.
|title=The Relationship of Accelerometer-Assessed Standing Time With and Without Ambulation and Mortality: The WHI OPACH Study.
|date=01.2019
|date=12.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30293724
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33225345
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.09.005
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa227
}}
}}
* {{medline-title
* {{medline-title
|title=The Cross-sectional and Longitudinal Associations Between IL-6, IL-10, and TNFα and Cognitive Outcomes in the Mayo Clinic Study of Aging.
|title=Age-related myofiber atrophy in old mice is reversed by ten weeks voluntary high-resistance wheel running.
|date=12.07.2019
|date=09.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30256904
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33181317
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625589
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111150
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of midlife cardiovascular risk factors on white matter hyperintensity volume and cognition two decades later in normal ageing women.
|title=Predicted Skeletal Muscle Mass and 4-Year Cardiovascular Disease Incidence in Middle-Aged and Elderly Participants of IKARIA Prospective Epidemiological Study: The Mediating Effect of Sex and Cardiometabolic Factors.
|date=02.2020
|date=27.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30259291
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33121164
|full-text-url=https://sci-hub.do/10.1007/s11682-018-9970-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693172
}}
}}
* {{medline-title
* {{medline-title
|title=Sex and age interact to determine clinicopathologic differences in Alzheimer's disease.
|title=Obesity is associated with early hip fracture risk in postmenopausal women: a 25-year follow-up.
|date=12.2018
|date=23.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30219939
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33095419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280837
|full-text-url=https://sci-hub.do/10.1007/s00198-020-05665-w
}}
}}
* {{medline-title
* {{medline-title
|title=Relationship Between Amyloid-β Positivity and Progression to Mild Cognitive Impairment or Dementia over 8 Years in Cognitively Normal Older Adults.
|title=ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells.
|date=2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30149452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33024871
|full-text-url=https://sci-hub.do/10.3233/JAD-180507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527645
}}
}}
* {{medline-title
* {{medline-title
|title=Lifetime Risk Factors for Functional and Cognitive Outcomes in Patients with Alzheimer's Disease.
|title=Effectiveness of adjuvant FOLFOX vs 5FU/LV in adults over age 65 with stage II and III colon cancer using a novel hybrid approach.
|date=2018
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30149448
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33015888
|full-text-url=https://sci-hub.do/10.3233/JAD-180303
|full-text-url=https://sci-hub.do/10.1002/pds.5148
}}
}}
* {{medline-title
* {{medline-title
|title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau.
|title=Age, Frailty, and Comorbidity as Prognostic Factors for Short-Term Outcomes in Patients With Coronavirus Disease 2019 in Geriatric Care.
|date=03.09.2018
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082275
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32978065
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7427570
}}
}}
* {{medline-title
* {{medline-title
|title=Childhood socioeconomic status and genetic risk for poorer cognition in later life.
|title=Clinical and demographic parameters predict the progression from mild cognitive impairment to dementia in elderly patients.
|date=09.2018
|date=12.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048844
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32918697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536306
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01697-8
}}
}}
* {{medline-title
* {{medline-title
|title=Diffuse Amyloid-β Plaques, Neurofibrillary Tangles, and the Impact of [[APOE]] in Elderly Persons' Brains Lacking Neuritic Amyloid Plaques.
|title=Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women.
|date=2018
|date=01.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040735
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32785663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537103
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526732
}}
}}
* {{medline-title
* {{medline-title
|title=Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain.
|title=High intensity interval training combined with L-citrulline supplementation: Effects on physical performance in healthy older adults.
|date=24.07.2018
|date=15.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30041668
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721549
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057096
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111036
}}
}}
* {{medline-title
* {{medline-title
|title=Dual-Task Gait and Alzheimer's Disease Genetic Risk in Cognitively Normal Adults: A Pilot Study.
|title=Associations of blood pressure with risk of injurious falls in old age vary by functional status: A cohort study.
|date=2018
|date=15.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30010120
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32738383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500574
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111038
}}
}}
* {{medline-title
* {{medline-title
|title=Higher Aortic Stiffness Is Related to Lower Cerebral Blood Flow and Preserved Cerebrovascular Reactivity in Older Adults.
|title=Epigenetic age acceleration and clinical outcomes in gliomas.
|date=30.10.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30018169
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32692766
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373289
}}
}}
* {{medline-title
* {{medline-title
|title=Physical activity effects on the individual alpha peak frequency of older adults with and without genetic risk factors for Alzheimer's Disease: A MEG study.
|title=Do Stairs Inhibit Seniors Who Live on Upper Floors From Going Out?
|date=09.2018
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32666833
|full-text-url=https://sci-hub.do/10.1016/j.clinph.2018.06.026
|full-text-url=https://sci-hub.do/10.1177/1937586720936588
}}
}}
* {{medline-title
* {{medline-title
|title=Racial and Ethnic Disparities in Dementia Risk Among Individuals With Low Education.
|title=Age-specific acute changes in carotid-femoral pulse wave velocity with head-up tilt.
|date=09.2018
|date=07.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30005921
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634245
|full-text-url=https://sci-hub.do/10.1016/j.jagp.2018.05.011
|full-text-url=https://sci-hub.do/10.1093/ajh/hpaa101
}}
}}
* {{medline-title
* {{medline-title
|title=Increased CAIDE dementia risk, cognition, CSF biomarkers, and vascular burden in healthy adults.
|title=Pre-frailty status increases the risk of rehospitalization in patients after elective cardiac surgery without complication.
|date=17.07.2018
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531126
|full-text-url=https://sci-hub.do/10.1212/WNL.0000000000005824
|full-text-url=https://sci-hub.do/10.1111/jocs.14550
}}
}}
* {{medline-title
* {{medline-title
|title=Differential 5-year brain atrophy rates in cognitively declining and stable [[APOE]]-ε4 elders.
|title=Comparative Performance of Creatinine-Based GFR Estimation Equations in Exceptional Longevity: The Rugao Longevity and Ageing Study.
|date=09.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29911873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32546991
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126943
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266309
}}
}}
* {{medline-title
* {{medline-title
|title=Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity.
|title=Sex-and race-specific associations of protein intake with change in muscle mass and physical function in older adults: the Health, Aging, and Body Composition (Health ABC) Study.
|date=10.2018
|date=01.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29890178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32520344
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326591
}}
}}
* {{medline-title
* {{medline-title
|title=Using event-related fMRI to examine sustained attention processes and effects of [[APOE]] ε4 in young adults.
|title=Deterioration of bone microstructure by aging and menopause in Japanese healthy women: analysis by [[HR]]-pQCT.
|date=2018
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29856823
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32519249
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983530
|full-text-url=https://sci-hub.do/10.1007/s00774-020-01115-z
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.
|title=Association between Low Protein Intake and Mortality in Patients with Type 2 Diabetes.
|date=2018
|date=01.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32492838
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352318
}}
}}
* {{medline-title
* {{medline-title
|title=White matter microstructure is altered in cognitively normal middle-aged [[APOE]]-ε4 homozygotes.
|title=CAUSES, mortality rates and risk factors of death in community-dwelling Europeans aged 50 years and over: Results from the Survey of Health, Ageing and Retirement in Europe 2013-2015.
|date=24.05.2018
|date=07-08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29793545
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32325305
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968505
|full-text-url=https://sci-hub.do/10.1016/j.archger.2020.104035
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of lifetime cumulative ginseng intake on cognitive function in late life.
|title=Estimation of Wave Condition Number From Pressure Waveform Alone and Its Changes With Advancing Age in Healthy Women and Men.
|date=24.05.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29793529
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32328003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968575
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161432
}}
}}
* {{medline-title
* {{medline-title
|title=Apolipoprotein E region molecular signatures of Alzheimer's disease.
|title=Extended in vitro culture of primary human mesenchymal stem cells downregulates Brca1-related genes and impairs DNA double-strand break recognition.
|date=08.2018
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797398
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32333827
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327915
}}
}}
* {{medline-title
* {{medline-title
|title=Does incipient dementia explain normal cognitive decline determinants? Lothian birth cohort 1921.
|title=Effect of artificial dawn light on cardiovascular function, alertness, and balance in middle-aged and older adults.
|date=06.2018
|date=13.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29745686
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32307533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001941
|full-text-url=https://sci-hub.do/10.1093/sleep/zsaa082
}}
}}
* {{medline-title
* {{medline-title
|title=An 18-mo randomized, double-blind, placebo-controlled trial of DHA-rich fish oil to prevent age-related cognitive decline in cognitively normal older adults.
|title=Heart Rate Performance Curve Is Dependent on Age, Sex, and Performance.
|date=01.05.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29722833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32300582
|full-text-url=https://sci-hub.do/10.1093/ajcn/nqx077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144539
}}
}}
* {{medline-title
* {{medline-title
|title=The Role of Apolipoprotein E and Ethanol Exposure in Age-Related Changes in Choline Acetyltransferase and Brain-Derived Neurotrophic Factor Expression in the Mouse Hippocampus.
|title=Physical activity trajectories, mortality, hospitalization, and disability in the Toledo Study of Healthy Aging.
|date=05.2018
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32163233
|full-text-url=https://sci-hub.do/10.1007/s12031-018-1074-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432572
}}
}}
* {{medline-title
* {{medline-title
|title=[[APOE]] genotype modifies the association between central arterial stiffening and cognition in older adults.
|title=U-Shaped Association of Plasma Testosterone, and no Association of Plasma Estradiol, with Incidence of Fractures in Men.
|date=07.2018
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32155267
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985659
|full-text-url=https://sci-hub.do/10.1210/clinem/dgaa115
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration.
|title=Pregnancy-Related Bone Mineral and Microarchitecture Changes in Women Aged 30 to 45 Years.
|date=2018
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660940
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32119748
|full-text-url=https://sci-hub.do/10.3233/JAD-171054
|full-text-url=https://sci-hub.do/10.1002/jbmr.3998
}}
}}
* {{medline-title
* {{medline-title
|title=Brain Aging and [[APOE]] ε4 Interact to Reveal Potential Neuronal Compensation in Healthy Older Adults.
|title=Analysis of the world record time for combined father and son marathon.
|date=2018
|date=01.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869204
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00819.2019
}}
}}
* {{medline-title
* {{medline-title
|title=Leisure-Time Physical Activity and the Risk of Incident Dementia: The Mayo Clinic Study of Aging.
|title=Age-related reductions in heart rate variability do not worsen during exposure to humid compared to dry heat: A secondary analysis.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29614667
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31934605
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900557
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949029
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of [[APOE]]-ε4 allele load on brain morphology in a cohort of middle-aged healthy individuals with enriched genetic risk for Alzheimer's disease.
|title=Efficacy and Safety of Dapagliflozin in the Elderly: Analysis From the DECLARE-TIMI 58 Study.
|date=07.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29605385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843945
|full-text-url=https://sci-hub.do/10.1016/j.jalz.2018.01.016
|full-text-url=https://sci-hub.do/10.2337/dc19-1476
}}
}}
* {{medline-title
* {{medline-title
|title=[[APOE]] influences working memory in non-demented elderly through an interaction with [[SPON1]] rs2618516.
|title=Validity of Prediction Equations of Maximal Heart Rate in Physically Active Female Adolescents and the Role of Maturation.
|date=07.2018
|date=13.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573041
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31766291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866309
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915545
}}
}}
* {{medline-title
* {{medline-title
|title=Altered effective connectivity anchored in the posterior cingulate cortex and the medial prefrontal cortex in cognitively intact elderly [[APOE]] ε4 carriers: a preliminary study.
|title=Base excision repair but not DNA double-strand break repair is impaired in aged human adipose-derived stem cells.
|date=02.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29549664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31782607
|full-text-url=https://sci-hub.do/10.1007/s11682-018-9857-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996963
}}
}}
* {{medline-title
* {{medline-title
|title=Plasma Cortisol, Brain Amyloid-β, and Cognitive Decline in Preclinical Alzheimer's Disease: A 6-Year Prospective Cohort Study.
|title=Urban-Rural Differences in Hip Fracture Mortality: A Nationwide NOREPOS Study.
|date=01.2017
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29560886
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31768493
|full-text-url=https://sci-hub.do/10.1016/j.bpsc.2016.08.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874178
}}
}}
* {{medline-title
* {{medline-title
|title=Apolipoprotein E genotypes and longevity across dementia disorders.
|title=Malnutrition as a Strong Predictor of the Onset of Sarcopenia.
|date=07.2018
|date=27.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29548722
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783482
|full-text-url=https://sci-hub.do/10.1016/j.jalz.2018.02.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950107
}}
}}
* {{medline-title
* {{medline-title
|title=Differential Effect of [[APOE]] ɛ4 Status and Elevated Pulse Pressure on Functional Decline in Cognitively Normal Older Adults.
|title=Acclimation to a thermoneutral environment abolishes age-associated alterations in heart rate and heart rate variability in conscious, unrestrained mice.
|date=2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29562507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31776883
|full-text-url=https://sci-hub.do/10.3233/JAD-170918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031176
}}
}}
* {{medline-title
* {{medline-title
|title=Functional segregation loss over time is moderated by [[APOE]] genotype in healthy elderly.
|title=Long-term dementia risk prediction by the LIBRA score: A 30-year follow-up of the CAIDE study.
|date=07.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520911
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31736136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866329
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003764
}}
}}
* {{medline-title
* {{medline-title
|title=Dementia Prevalence in Greece: The Hellenic Longitudinal Investigation of Aging and Diet (HELIAD).
|title=Kidney function and its association to imminent, short- and long-term fracture risk-a longitudinal study in older women.
|date=07-09.2018
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528855
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754754
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000249
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946753
}}
}}
* {{medline-title
* {{medline-title
|title=Atypical Localization and Dissociation between Glucose Uptake and Amyloid Deposition in Cognitively Normal [[APOE]]*E4 Homozygotic Elders Compared with Patients with Late-Onset Alzheimer's Disease.
|title=Oxidatively Damaged DNA/RNA and 8-Isoprostane Levels Are Associated With the Development of Type 2 Diabetes at Older Age: Results From a Large Cohort Study.
|date=01-02.2018
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29497704
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830350
|full-text-url=https://sci-hub.do/10.2337/dc19-1379
}}
}}
* {{medline-title
* {{medline-title
|title=Association between subjective memory assessment and associative memory performance: Role of ad risk factors.
|title=Associations of vigorous physical activity with all-cause, cardiovascular and cancer mortality among 64 913 adults.
|date=02.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29494182
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31548909
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733336
}}
}}
* {{medline-title
* {{medline-title
|title=Reduced Gray Matter Volume of the Thalamus and Hippocampal Region in Elderly Healthy Adults with no Impact of [[APOE]] ɛ4: A Longitudinal Voxel-Based Morphometry Study.
|title=Reduced cerebrovascular and cardioventilatory responses to intermittent hypoxia in elderly.
|date=2018
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29480170
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31557538
|full-text-url=https://sci-hub.do/10.3233/JAD-161036
|full-text-url=https://sci-hub.do/10.1016/j.resp.2019.103306
}}
}}
* {{medline-title
* {{medline-title
|title=Apolipoprotein E genotype does not moderate the associations of depressive symptoms, neuroticism and allostatic load with cognitive ability and cognitive aging in the Lothian Birth Cohort 1936.
|title=Vestibulo-sympathetic reflex in patients with bilateral vestibular loss.
|date=2018
|date=01.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29451880
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31513442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815580
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00466.2019
}}
}}
* {{medline-title
* {{medline-title
|title=A Network of Genetic Effects on Non-Demented Cognitive Aging: Alzheimer's Genetic Risk (CLU + CR1 + PICALM) Intensifies Cognitive Aging Genetic Risk (COMT + BDNF) Selectively for [[APOE]]ɛ4 Carriers.
|title=Heart rate and blood pressure in male Ts65Dn mice: a model to investigate cardiovascular responses in Down syndrome.
|date=2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29480189
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31496136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830167
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732568
}}
}}
* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=Body weight at 10 years of age and change in body composition between 8 and 10 years of age were related to survival in a longitudinal study of 39 Labrador retriever dogs.
|date=28.03.2018
|date=09.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500653
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734441
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Variation in [[FOXO3]] is Associated with Self-Rated Health in a Population-Based Sample of Older Individuals.
|title=Dietary diversity offsets the adverse mortality risk among older indigenous Taiwanese.
|date=08.10.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415201
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31464406
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175024
|full-text-url=https://sci-hub.do/10.6133/apjcn.201909_28(3).0019
}}
}}
* {{medline-title
* {{medline-title
|title=[[APOE]] ε4 Genotype and Cognitive Reserve Effects on the Cognitive Functioning of Healthy Elders.
|title=Independent and joint effects of vascular and cardiometabolic risk factor pairs for risk of all-cause dementia: a prospective population-based study.
|date=2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29414814
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31455442
|full-text-url=https://sci-hub.do/10.1159/000481852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948010
}}
}}
* {{medline-title
* {{medline-title
|title=Distinct neural correlates of episodic memory among apolipoprotein E alleles in cognitively normal elderly.
|title=Work Ability and Job Survival: Four-Year Follow-Up.
|date=02.2019
|date=28.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29396739
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31466415
|full-text-url=https://sci-hub.do/10.1007/s11682-017-9818-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747402
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis.
|title=Predictivity of bioimpedance phase angle for incident disability in older adults.
|date=06.12.2017
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216448
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31436391
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728673
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015240
}}
}}
* {{medline-title
* {{medline-title
|title=Features associated with cognitive impairment and dementia in a community-based sample of illiterate elderly aged 75+ years: the Pietà study.
|title=Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study.
|date=04-06.2014
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29213893
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619119
|full-text-url=https://sci-hub.do/10.1111/jgs.16089
}}
}}
* {{medline-title
* {{medline-title
|title=Epistasis, physical capacity-related genes and exceptional longevity: [[FNDC5]] gene interactions with candidate genes FOXOA3 and [[APOE]].
|title=Birthweight in offspring and cardiovascular mortality in their parents, aunts and uncles: a family-based cohort study of 1.35 million births.
|date=14.11.2017
|date=01.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31325357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688477
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124506
}}
}}
* {{medline-title
* {{medline-title
|title=Neuronal hyperactivity due to loss of inhibitory tone in [[APOE]]4 mice lacking Alzheimer's disease-like pathology.
|title=Younger- vs Older-Old Patients with Heart Failure with Preserved Ejection Fraction.
|date=13.11.2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29133888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684208
|full-text-url=https://sci-hub.do/10.1111/jgs.16050
}}
}}
* {{medline-title
* {{medline-title
|title=Green space and cognitive ageing: A retrospective life course analysis in the Lothian Birth Cohort 1936.
|title=Comparison of Immune Checkpoint Inhibitors between Older and Younger Patients with Advanced or Metastatic Lung Cancer: A Systematic Review and Meta-Analysis.
|date=01.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29128786
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31214620
|full-text-url=https://sci-hub.do/10.1016/j.socscimed.2017.10.038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535828
}}
}}
* {{medline-title
* {{medline-title
|title=Preclinical effects of [[APOE]] ε4 on cerebrospinal fluid Aβ42 concentrations.
|title=Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study.
|date=23.10.2017
|date=12.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29061195
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31186007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654097
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560907
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide meta-analysis associates HLA-DQA1/DRB1 and [[LPA]] and lifestyle factors with human longevity.
|title=Fed and fasted states on heart rate variability, hemodynamic heart rate and blood pressure in adults submitted to moderate aerobic exercise.
|date=13.10.2017
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29030599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31193402
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527814
}}
}}
* {{medline-title
* {{medline-title
|title=Phenome and genome based studies into human ageing and longevity: An overview.
|title=Structure Characterization and Action Mechanism of an Antiaging New Compound from [i]Gastrodia elata[/i] Blume.
|date=09.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28951210
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31198492
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2017.09.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526511
}}
}}
* {{medline-title
* {{medline-title
|title=A Tale of Two Genes: Microglial Apoe and Trem2.
|title=Effects of Whole-Body Vibration Therapy on Distal Tibial Myotendinous Density and Volume: A Randomized Controlled Trial in Postmenopausal Women.
|date=19.09.2017
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28930654
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31131343
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2017.08.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524674
}}
}}
* {{medline-title
* {{medline-title
|title=The Association of Apolipoprotein E Gene Polymorphism With Cognitive Performance in Nondemented Polish Adults Aged 55 to 75.
|title=Smoking cessation and risk of recurrent cardiovascular events and mortality after a first manifestation of arterial disease.
|date=09.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28844148
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31132583
|full-text-url=https://sci-hub.do/10.1177/0091415017724548
|full-text-url=https://sci-hub.do/10.1016/j.ahj.2019.03.019
}}
}}
* {{medline-title
* {{medline-title
|title=Cognitive Aging in Black and White Americans: Cognition, Cognitive Decline, and Incidence of Alzheimer Disease Dementia.
|title=The Association of Aromatic Amino Acids with Incident Hip Fracture, aBMD, and Body Composition from the Cardiovascular Health Study.
|date=01.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28863046
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31115639
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718953
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663558
}}
}}
* {{medline-title
* {{medline-title
|title=Alzheimer's Disease Biomarkers Interactively Influence Physical Activity, Mobility, and Cognition Associations in a Non-Demented Aging Population.
|title=Impact of handgrip strength on cardiovascular, cancer and all-cause mortality in the Korean longitudinal study of ageing.
|date=2017
|date=09.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28800331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31072857
|full-text-url=https://sci-hub.do/10.3233/JAD-170130
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527975
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort.
|title=Vitamin K Status and Mobility Limitation and Disability in Older Adults: The Health, Aging, and Body Composition Study.
|date=2017
|date=09.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28800603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056634
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328196
}}
}}
==MSC==
* {{medline-title
* {{medline-title
|title=Rejuvenation of Senescent Endothelial Progenitor Cells by Extracellular Vesicles Derived From Mesenchymal Stromal Cells.
|title=Effects of a clinical medication review focused on personal goals, quality of life, and health problems in older persons with polypharmacy: A randomised controlled trial (DREAMeR-study).
|date=11.2020
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33294742
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31067214
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691285
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505828
}}
}}
* {{medline-title
* {{medline-title
|title=Extracellular vesicles derived from bone marrow mesenchymal stem cells enhance myelin maintenance after cortical injury in aged rhesus monkeys.
|title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair.
|date=29.11.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33264634
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2020.113540
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001
}}
}}
* {{medline-title
* {{medline-title
|title=TPP1 Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the MRE11/AKT Pathway.
|title=Relationship Between Sex Steroids and Deterioration of Bone Microarchitecture in Older Men: The Prospective STRAMBO Study.
|date=2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33195247
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30995347
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658181
|full-text-url=https://sci-hub.do/10.1002/jbmr.3746
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-Affected [[MSC]] Functions and Severity of Periodontal Tissue Destruction in a Ligature-Induced Mouse Periodontitis Model.
|title=Sex And Prognostic Significance of Self-Reported Frailty in Non-ST-Segment Elevation Acute Coronary Syndromes: Insights From the TRILOGY ACS Trial.
|date=30.10.2020
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143068
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30935633
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663404
|full-text-url=https://sci-hub.do/10.1016/j.cjca.2018.12.035
}}
}}
* {{medline-title
* {{medline-title
|title=Human placenta-derived mesenchymal stem cells stimulate ovarian function via miR-145 and bone morphogenetic protein signaling in aged rats.
|title=Plasma 25-Hydroxyvitamin D Concentrations Are Inversely Associated with All-Cause Mortality among a Prospective Cohort of Chinese Adults Aged ≥80 Years.
|date=05.11.2020
|date=01.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33153492
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30949685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543202
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal Stromal Cells as Critical Contributors to Tissue Regeneration.
|title=Sex-specific associations between body mass index and death before life expectancy: a comparative study from the USA and Sweden.
|date=2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33102483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30947624
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461107
}}
}}
* {{medline-title
* {{medline-title
|title=The biology of human hair greying.
|title=Correlation between patients' age and cancer immunotherapy efficacy.
|date=23.09.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32965076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30906662
|full-text-url=https://sci-hub.do/10.1111/brv.12648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422380
}}
}}
* {{medline-title
* {{medline-title
|title=[i]Tsc1[/i] Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells.
|title=Understanding the responsiveness of nitric oxide to acute eccentric resistance exercise in elderly obese women.
|date=10.09.2020
|date=20.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32927859
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30873464
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410657
}}
}}
* {{medline-title
* {{medline-title
|title=The role of mitochondrial dysfunction in mesenchymal stem cell senescence.
|title=Age-dependent changes in metabolite profile and lipid saturation in dystrophic mice.
|date=12.2020
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32803322
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30848538
|full-text-url=https://sci-hub.do/10.1007/s00441-020-03272-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777843
}}
}}
* {{medline-title
* {{medline-title
|title=Metabolic syndrome increases senescence-associated micro-RNAs in extracellular vesicles derived from swine and human mesenchymal stem/stromal cells.
|title=Investigating dose-response effects of multimodal exercise programs on health-related quality of life in older adults.
|date=12.08.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32787856
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30774322
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425605
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352872
}}
}}
* {{medline-title
* {{medline-title
|title=Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses.
|title=Methylation-Based Biological Age and Breast Cancer Risk.
|date=22.07.2020
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32699947
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30794318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792078
}}
}}
* {{medline-title
* {{medline-title
|title=Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organization in stress-induced senescence of [[MSC]]s.
|title=Prospective association between adherence to the MIND diet and subjective memory complaints in the French NutriNet-Santé cohort.
|date=13.07.2020
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32660632
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359252
|full-text-url=https://sci-hub.do/10.1007/s00415-019-09218-y
}}
}}
* {{medline-title
* {{medline-title
|title=Increased cellular senescence in the murine and human stenotic kidney: Effect of mesenchymal stem cells.
|title=Relationship between physical and cognitive performance in community dwelling, ethnically diverse older adults: a cross-sectional study.
|date=02.2021
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32657444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30643695
|full-text-url=https://sci-hub.do/10.1002/jcp.29940
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327882
}}
}}
* {{medline-title
* {{medline-title
|title=Intrinsic Type 1 Interferon (IFN1) Profile of Uncultured Human Bone Marrow CD45 CD271  Multipotential Stromal Cells (BM-[[MSC]]s): The Impact of Donor Age, Culture Expansion and IFNα and IFNβ Stimulation.
|title=Associations of Hearing Loss and Depressive Symptoms With Incident Disability in Older Adults: Health, Aging, and Body Composition Study.
|date=15.07.2020
|date=14.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32679782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30561511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399891
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328205
}}
}}
* {{medline-title
* {{medline-title
|title=Facial rejuvenation using stem cell conditioned media combined with skin needling: A split-face comparative study.
|title=Effects of a 12-Week Aerobic Spin Intervention on Resting State Networks in Previously Sedentary Older Adults.
|date=09.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32623814
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30542314
|full-text-url=https://sci-hub.do/10.1111/jocd.13594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277752
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges.
|title=Erythrocyte sedimentation rate as an independent prognostic marker for mortality: a prospective population-based cohort study.
|date=2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32582691
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537394
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283395
|full-text-url=https://sci-hub.do/10.1111/joim.12853
}}
}}
* {{medline-title
* {{medline-title
|title=The changing epigenetic landscape of Mesenchymal Stem/Stromal Cells during aging.
|title=Moderate Aerobic Training Decreases Blood Pressure but No Other Cardiovascular Risk Factors in Hypertensive Overweight/Obese Elderly Patients.
|date=08.2020
|date=01-12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32445894
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30450368
|full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115440
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236479
}}
}}
* {{medline-title
* {{medline-title
|title=Dual Role of Autophagy in Regulation of Mesenchymal Stem Cell Senescence.
|title=The burden of common variable immunodeficiency disorders: a retrospective analysis of the European Society for Immunodeficiency (ESID) registry data.
|date=2020
|date=12.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32391362
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30419968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193103
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233554
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular Aspects of Adipose-Derived Stromal Cell Senescence in a Long-Term Culture: A Potential Role of Inflammatory Pathways.
|title=Survival after non-traumatic spinal cord injury: evidence from a population-based rehabilitation cohort in Switzerland.
|date=01-12.2020
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32314614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30413804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586277
|full-text-url=https://sci-hub.do/10.1038/s41393-018-0212-x
}}
}}
* {{medline-title
* {{medline-title
|title=Human Obesity Induces Dysfunction and Early Senescence in Adipose Tissue-Derived Mesenchymal Stromal/Stem Cells.
|title=Is there a correlation between an eGFR slope measured over a 5-year period and incident cardiovascular events in the following 5 years among a Flemish general practice population: a retrospective cohort study.
|date=2020
|date=12.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32274385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30420350
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113401
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252738
}}
}}
* {{medline-title
* {{medline-title
|title=miR-155-5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction.
|title=Biphasic concentration-dependent interaction between imidacloprid and dietary phytochemicals in honey bees (Apis mellifera).
|date=04.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32196916
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30383869
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189985
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211726
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal Stem Cell Derived Extracellular Vesicles in Aging.
|title=Heart rate variability in middle-aged sprint and endurance athletes.
|date=2020
|date=01.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32154253
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389479
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047768
|full-text-url=https://sci-hub.do/10.1016/j.physbeh.2018.10.018
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular Mechanisms Contributing to Mesenchymal Stromal Cell Aging.
|title=Serum cystatin C, impaired kidney function, and geriatric depressive symptoms among older people living in a rural area: a population-based study.
|date=21.02.2020
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32098040
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400830
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072652
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219054
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of DNA Methyltransferase by RG108 Promotes Pluripotency-Related Character of Porcine Bone Marrow Mesenchymal Stem Cells.
|title=Office and Ambulatory Heart Rate as Predictors of Age-Related Kidney Function Decline.
|date=04.2020
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32125888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354758
|full-text-url=https://sci-hub.do/10.1089/cell.2019.0060
|full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.118.11594
}}
}}
* {{medline-title
* {{medline-title
|title=Extracellular Vesicles of Stem Cells to Prevent BRONJ.
|title=Aging Alters the Relative Contributions of the Sympathetic and Parasympathetic Nervous System to Blood Pressure Control in Women.
|date=05.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32119600
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354803
|full-text-url=https://sci-hub.do/10.1177/0022034520906793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211807
}}
}}
* {{medline-title
* {{medline-title
|title=Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells.
|title=Association between treatment of superficial bladder cancer and 10-year mortality in older adults with multiple chronic conditions.
|date=2019
|date=01.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32038244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30289971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6989539
|full-text-url=https://sci-hub.do/10.1002/cncr.31705
}}
}}
* {{medline-title
* {{medline-title
|title=The Importance of Stem Cell Senescence in Regenerative Medicine.
|title=Conjoint differences in inhibitory control and processing speed in childhood to older adult cohorts: Discriminant functions from a Go/No-Go task.
|date=2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32026416
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30284853
|full-text-url=https://sci-hub.do/10.1007/5584_2020_489
|full-text-url=https://sci-hub.do/10.1037/pag0000299
}}
}}
* {{medline-title
* {{medline-title
|title=Control of mesenchymal stem cell biology by histone modifications.
|title=Heart Rate Fragmentation as a Novel Biomarker of Adverse Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis.
|date=2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32025282
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30233384
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996187
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129761
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of mesenchymal stem cell senescence on inflammaging.
|title=Partial nephrectomy is not associated with an overall survival advantage over radical nephrectomy in elderly patients with stage Ib-II renal masses: An analysis of the national cancer data base.
|date=02.2020
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31964472
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30207380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061209
|full-text-url=https://sci-hub.do/10.1002/cncr.31582
}}
}}
* {{medline-title
* {{medline-title
|title=Late Rescue Therapy with Cord-Derived Mesenchymal Stromal Cells for Established Lung Injury in Experimental Bronchopulmonary Dysplasia.
|title=Uraemia-induced immune senescence and clinical outcomes in chronic kidney disease patients.
|date=15.03.2020
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31918630
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30202981
|full-text-url=https://sci-hub.do/10.1089/scd.2019.0116
|full-text-url=https://sci-hub.do/10.1093/ndt/gfy276
}}
}}
* {{medline-title
* {{medline-title
|title=Low-Level Radiofrequency Exposure Does Not Induce Changes in [[MSC]] Biology: An in vitro Study for the Prevention of NIR-Related Damage.
|title=Cognitive functioning transitions, health expectancies, and inequalities among elderly people in China: A nationwide longitudinal study.
|date=2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31908499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927227
|full-text-url=https://sci-hub.do/10.1002/gps.4966
}}
}}
* {{medline-title
* {{medline-title
|title=Macrophage migration inhibitory factor rejuvenates aged human mesenchymal stem cells and improves myocardial repair.
|title=Diurnal rhythms of heart and respiratory rates in donkeys of different age groups during the cold-dry and hot-dry seasons in a tropical savannah.
|date=27.12.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31881006
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187687
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949107
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125241
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of olive oil and its components on mesenchymal stem cell biology.
|title=Absolute 10-year risk of dementia by age, sex and [i]APOE[/i] genotype: a population-based cohort study.
|date=26.12.2019
|date=04.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31875868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30181149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904865
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148649
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic Regulation of Mesenchymal Stem Cell Homeostasis.
|title=Testosterone Levels and Type 2 Diabetes-No Correlation with Age, Differential Predictive Value in Men and Women.
|date=02.2020
|date=20.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31866188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30127326
|full-text-url=https://sci-hub.do/10.1016/j.tcb.2019.11.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165105
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal Stem Cells: Allogeneic [[MSC]] May Be Immunosuppressive but Autologous [[MSC]] Are Dysfunctional in Lupus Patients.
|title=Vegetable Diversity, Injurious Falls, and Fracture Risk in Older Women: A Prospective Cohort Study.
|date=2019
|date=13.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31799252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30104494
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115713
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of high glucose conditions on the expansion and differentiation capabilities of mesenchymal stromal cells derived from rat endosteal niche.
|title=Evidence of oxidative stress-induced senescence in mature, post-mature and pathological human placentas.
|date=21.11.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31752674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873668
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083404
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagy inhibits the mesenchymal stem cell aging induced by D-galactose through ROS/JNK/p38 signalling.
|title=Enoch Senior's College for Korean Immigrant Seniors: Quality of Life Effects.
|date=03.2020
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31675454
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30058523
|full-text-url=https://sci-hub.do/10.1111/1440-1681.13207
|full-text-url=https://sci-hub.do/10.1017/S0714980818000211
}}
}}
* {{medline-title
* {{medline-title
|title=Enhancing survival, engraftment, and osteogenic potential of mesenchymal stem cells.
|title=Non-AIDS Mortality Is Higher Among Successfully Treated People Living with HIV Compared with Matched HIV-Negative Control Persons: A 15-Year Follow-Up Cohort Study in Sweden.
|date=26.10.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31692976
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30067408
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828596
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088250
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development.
|title=Gain without pain: Glucose promotes cognitive engagement and protects positive affect in older adults.
|date=22.10.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31644429
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29999390
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834426
|full-text-url=https://sci-hub.do/10.1037/pag0000270
}}
}}
* {{medline-title
* {{medline-title
|title=Embryonic stem cell-derived extracellular vesicles enhance the therapeutic effect of mesenchymal stem cells.
|title=Ten-year changes in ambulatory blood pressure: The prognostic value of ambulatory pulse pressure.
|date=2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31660081
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29981188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815953
|full-text-url=https://sci-hub.do/10.1111/jch.13344
}}
}}
* {{medline-title
* {{medline-title
|title=Survival of aging CD264  and CD264  populations of human bone marrow mesenchymal stem cells is independent of colony-forming efficiency.
|title=Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts.
|date=01.2020
|date=15.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31612990
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29982474
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6906265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376108
}}
}}
* {{medline-title
* {{medline-title
|title=Differential effects of extracellular vesicles from aging and young mesenchymal stem cells in acute lung injury.
|title=Supplementation with resveratrol as Polygonum cuspidatum Sieb. et Zucc. extract induces changes in the excretion of urinary markers associated to aging in rats.
|date=29.09.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31575829
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29959053
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781978
|full-text-url=https://sci-hub.do/10.1016/j.fitote.2018.06.022
}}
}}
* {{medline-title
* {{medline-title
|title=Connexin43 is Dispensable for Early Stage Human Mesenchymal Stem Cell Adipogenic Differentiation But is Protective against Cell Senescence.
|title=Subjective cognitive decline and risk of MCI: The Mayo Clinic Study of Aging.
|date=11.09.2019
|date=24.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31514306
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29959257
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770901
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070384
}}
}}
* {{medline-title
* {{medline-title
|title=Maintained Properties of Aged Dental Pulp Stem Cells for Superior Periodontal Tissue Regeneration.
|title=Maternal gene [i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes.
|date=08.2019
|date=18.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31440385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675537
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085769
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal Stem Cells in Homeostasis and Systemic Diseases: Hypothesis, Evidences, and Therapeutic Opportunities.
|title=Progression of frailty and prevalence of osteoporosis in a community cohort of older women-a 10-year longitudinal study.
|date=31.07.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31370159
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29947868
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154042
}}
}}
* {{medline-title
* {{medline-title
|title=Tunneling nanotubes mediate the expression of senescence markers in mesenchymal stem/stromal cell spheroids.
|title=Higher spermidine intake is linked to lower mortality: a prospective population-based study.
|date=01.2020
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298767
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955838
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954984
|full-text-url=https://sci-hub.do/10.1093/ajcn/nqy102
}}
}}
* {{medline-title
* {{medline-title
|title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity.
|title=Childhood IQ and mortality during 53 years' follow-up of Swedish men and women.
|date=08.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29925669
|full-text-url=https://sci-hub.do/10.1089/cell.2019.0010
|full-text-url=https://sci-hub.do/10.1136/jech-2018-210675
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of aging on behaviour of mesenchymal stem cells.
|title=Age-related changes in cardiac electrophysiology and calcium handling in response to sympathetic nerve stimulation.
|date=26.06.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31293716
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29938794
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117583
}}
}}
* {{medline-title
* {{medline-title
|title=Human colorectal cancer derived-[[MSC]]s promote tumor cells escape from senescence via P53/P21 pathway.
|title=Physical activity and sedentary behavior in relation to mortality among renal cell cancer survivors.
|date=04.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29894512
|full-text-url=https://sci-hub.do/10.1007/s12094-019-02152-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997343
}}
}}
* {{medline-title
* {{medline-title
|title=Rapid Detection of Senescent Mesenchymal Stromal Cells by a Fluorescent Probe.
|title=Increased CAIDE dementia risk, cognition, CSF biomarkers, and vascular burden in healthy adults.
|date=10.2019
|date=17.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218816
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898969
|full-text-url=https://sci-hub.do/10.1002/biot.201800691
|full-text-url=https://sci-hub.do/10.1212/WNL.0000000000005824
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotinamide phosphoribosyltransferase postpones rat bone marrow mesenchymal stem cell senescence by mediating NAD -Sirt1 signaling.
|title=Associations Between Heart Rate Recovery Dynamics With Estradiol Levels in 20 to 60 Year-Old Sedentary Women.
|date=07.06.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29867572
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594813
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962759
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of senescent cells in multipotent mesenchymal stromal cell cultures: Current methods and future directions.
|title=Prognostic value of age adjusted segment involvement score as measured by coronary computed tomography: a potential marker of vascular age.
|date=08.2019
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797058
|full-text-url=https://sci-hub.do/10.1016/j.jcyt.2019.05.001
|full-text-url=https://sci-hub.do/10.1007/s00380-018-1188-3
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Stability of Mesenchymal Stromal Cells for Regenerative Medicine Applications: A Fundamental Biosafety Aspect.
|title=The Acute Effects of Age and Particulate Matter Exposure on Heart Rate and Heart Rate Variability in Mice.
|date=15.05.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31096604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566307
|full-text-url=https://sci-hub.do/10.1007/s12012-018-9461-3
}}
}}
* {{medline-title
* {{medline-title
|title=Quantifying Senescence-Associated Phenotypes in Primary Multipotent Mesenchymal Stromal Cell Cultures.
|title=Neuroticism predicts all-cause mortality over 19-years: The moderating effects on functional status, and the angiotensin-converting enzyme.
|date=2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31020633
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29764603
|full-text-url=https://sci-hub.do/10.1007/7651_2019_217
|full-text-url=https://sci-hub.do/10.1016/j.jpsychores.2018.04.013
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the [[SIRT1]] pathway in aged bone marrow.
|title=Anxiety and 10-Year Risk of Incident Dementia-An Association Shaped by Depressive Symptoms: Results of the Prospective Three-City Study.
|date=18.04.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31000692
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472410
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913372
}}
}}
* {{medline-title
* {{medline-title
|title=Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro.
|title=Delirium as a predictor of mortality in US Medicare beneficiaries discharged from the emergency department: a national claims-level analysis up to 12 months.
|date=08.2019
|date=05.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730630
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942463
}}
}}
* {{medline-title
* {{medline-title
|title=Alterations in genetic and protein content of swine adipose tissue-derived mesenchymal stem cells in the metabolic syndrome.
|title=Prognostic value of cardiac troponin I assay in hospitalized elderly patients.
|date=05.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30933719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728985
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545577
|full-text-url=https://sci-hub.do/10.1007/s40520-018-0965-2
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating factors present in the sera of naturally skinny people may influence cell commitment and adipocyte differentiation of mesenchymal stromal cells.
|title=The influence of participation on mortality in very old age among community-living people in Sweden.
|date=26.03.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30949296
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29679295
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373378
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal stem cell therapy improves spatial memory and hippocampal structure in aging rats.
|title=Mediterranean diet and hip fracture incidence among older adults: the CHANCES project.
|date=18.11.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30951751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656347
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2019.04.001
|full-text-url=https://sci-hub.do/10.1007/s00198-018-4517-6
}}
}}
* {{medline-title
* {{medline-title
|title=Immunophenotypic characterization, multi-lineage differentiation and aging of zebrafish heart and liver tissue-derived mesenchymal stem cells as a novel approach in stem cell-based therapy.
|title=Depression in type 1 diabetes and risk of dementia.
|date=04.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30947959
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29634288
|full-text-url=https://sci-hub.do/10.1016/j.tice.2019.01.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179940
}}
}}
* {{medline-title
* {{medline-title
|title=Accumulating Transcriptome Drift Precedes Cell Aging in Human Umbilical Cord-Derived Mesenchymal Stromal Cells Serially Cultured to Replicative Senescence.
|title=Testosterone and All-Cause Mortality in Older Men: The Role of Metabolic Syndrome.
|date=09.2019
|date=01.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30924318
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848820
}}
}}
* {{medline-title
* {{medline-title
|title=Cell Therapy for Knee Osteoarthritis: Mesenchymal Stromal Cells.
|title=Arterial stiffening is a heritable trait associated with arterial dilation but not wall thickening: a longitudinal study in the twins UK cohort.
|date=2019
|date=21.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30897578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590330
|full-text-url=https://sci-hub.do/10.1159/000496605
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012080
}}
}}
* {{medline-title
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|title=Pulmonary Hypertension in Central Australia: A Community-Based Cohort Study.
|date=18.03.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29599030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
|full-text-url=https://sci-hub.do/10.1016/j.hlc.2018.02.020
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of [[HOXB7]] overexpression on human adipose-derived mesenchymal progenitors.
|title=The application of the palliative prognostic index in predicting the life expectancy of patients in palliative care: a systematic review and meta-analysis.
|date=19.03.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29572610
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423808
|full-text-url=https://sci-hub.do/10.1007/s40520-018-0928-7
}}
}}
* {{medline-title
* {{medline-title
|title=Bmi1 Overexpression in Mesenchymal Stem Cells Exerts Antiaging and Antiosteoporosis Effects by Inactivating p16/p19 Signaling and Inhibiting Oxidative Stress.
|title=Weight loss in men in late life and bone strength and microarchitecture: a prospective study.
|date=09.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30895687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29572622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851636
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035779
}}
}}
* {{medline-title
* {{medline-title
|title=An early-senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro-inflammatory program.
|title=[The life span of red blood cell in patients with severe/very severe aplastic anemia].
|date=06.2019
|date=14.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30828977
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29562449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516180
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342569
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Dairy product consumption and its association with metabolic disturbance in a prospective study of urban adults.
|date=15.04.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29553032
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863589
}}
}}
* {{medline-title
* {{medline-title
|title=Overexpression of [[ERBB4]] rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
|title=Factors associated with polypharmacy in primary care: a cross-sectional analysis of data from The English Longitudinal Study of Ageing (ELSA).
|date=03.2019
|date=14.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540422
|full-text-url=https://sci-hub.do/10.1096/fj.201801690R
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857661
}}
}}
* {{medline-title
* {{medline-title
|title=MiR-1292 Targets [[FZD4]] to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway.
|title=Do Patients Live Longer After THA and Is the Relative Survival Diagnosis-specific?
|date=12.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29489471
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263594
}}
}}
* {{medline-title
* {{medline-title
|title=Aging of mesenchymal stem cells: Implication in regenerative medicine.
|title=The relationship between excessive daytime sleepiness, disability, and mortality, and implications for life expectancy.
|date=12.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30525083
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222976
|full-text-url=https://sci-hub.do/10.1016/j.sleep.2017.11.1132
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of intra-ovarian injection of mesenchymal stem cells in aged mares.
|title=Long-Term Atherosclerotic Vascular Disease Risk and Prognosis in Elderly Women With Abdominal Aortic Calcification on Lateral Spine Images Captured During Bone Density Testing: A Prospective Study.
|date=03.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30470961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29443425
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439078
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415911
}}
}}
* {{medline-title
* {{medline-title
|title=Adipogenic and Osteogenic Differentiation of In Vitro Aged Human Mesenchymal Stem Cells.
|title=Age-related changes in with-the-rule and oblique corneal astigmatism.
|date=2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30484146
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369508
|full-text-url=https://sci-hub.do/10.1007/7651_2018_197
|full-text-url=https://sci-hub.do/10.1111/aos.13683
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of senescent secretory phenotype acquisition on human retinal pigment epithelial stem cells.
|title=Ageing perceptions and non-adherence to aromatase inhibitors among breast cancer survivors.
|date=16.11.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444724
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29329697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803454
}}
}}
* {{medline-title
* {{medline-title
|title=Comparison of Oxidative Stress Effects on Senescence Patterning of Human Adult and Perinatal Tissue-Derived Stem Cells in Short and Long-term Cultures.
|title=The prospective and concurrent effect of exercise on health related quality of life in older adults over a 3 year period.
|date=2018
|date=16.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30443170
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338743
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771011
}}
}}
* {{medline-title
* {{medline-title
|title=Evaluation of human mesenchymal stem cell senescence, differentiation and secretion behavior cultured on polycarbonate cell culture inserts.
|title=Utility of Time and Frequency Domain Parameters of Heart Rate Variability in the Context of Autonomic Disorders Characterized by Orthostatic Dysfunction.
|date=2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30372670
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29342011
|full-text-url=https://sci-hub.do/10.3233/CH-189322
|full-text-url=https://sci-hub.do/10.1097/WNP.0000000000000452
}}
}}
* {{medline-title
* {{medline-title
|title=Characterization of embryonic stem cell-differentiated fibroblasts as mesenchymal stem cells with robust expansion capacity and attenuated innate immunity.
|title=Association Between Heart Rate and Subclinical Cerebrovascular Disease in the Elderly.
|date=25.10.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30359317
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29284731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870891
}}
}}
* {{medline-title
* {{medline-title
|title=Can mesenchymal stem cell lysate reverse aging?
|title=An additive effect of leading role in the organization between social participation and dementia onset among Japanese older adults: the AGES cohort study.
|date=24.10.2018
|date=29.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362957
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29284406
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224235
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747184
}}
}}
* {{medline-title
* {{medline-title
|title=The [[GDF11]]-[[FTO]]-PPARγ axis controls the shift of osteoporotic [[MSC]] fate to adipocyte and inhibits bone formation during osteoporosis.
|title=Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions.
|date=12.2018
|date=04.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249653
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.09.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756112
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence of bone marrow-derived mesenchymal stem cells from patients with idiopathic pulmonary fibrosis.
|title=Metabolites Associated With Risk of Developing Mobility Disability in the Health, Aging and Body Composition Study.
|date=26.09.2018
|date=01.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30257725
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29186400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298186
}}
}}
* {{medline-title
* {{medline-title
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|title=Which Sleep Health Characteristics Predict All-Cause Mortality in Older Men? An Application of Flexible Multivariable Approaches.
|date=10.2018
|date=01.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29165696
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806578
}}
}}
* {{medline-title
* {{medline-title
|title=Regenerative potential of human nucleus pulposus resident stem/progenitor cells declines with ageing and intervertebral disc degeneration.
|title=Social isolation, health literacy, and mortality risk: Findings from the English Longitudinal Study of Ageing.
|date=10.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30015833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172607
|full-text-url=https://sci-hub.do/10.3892/ijmm.2018.3766
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794512
}}
* {{medline-title
|title=Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29980291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733253
}}
}}
* {{medline-title
* {{medline-title
|title=Hybrid complexes of high and low molecular weight hyaluronan delay in vitro replicative senescence of mesenchymal stromal cells: a pilot study for future therapeutic application.
|title=Bone Loss at the Hip and Subsequent Mortality in Older Men: The Osteoporotic Fractures in Men (MrOS) Study.
|date=12.07.2018
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30001217
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29124252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075440
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673261
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal Stromal Cell Characteristics and Regenerative Potential in Cardiovascular Disease: Implications for Cellular Therapy.
|title=Thyroid status and mortality in nonagenarians from long-lived families and the general population.
|date=05.2018
|date=25.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29895169
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29070732
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047272
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680564
}}
}}
* {{medline-title
* {{medline-title
|title=Elevated levels of the small GTPase Cdc42 induces senescence in male rat mesenchymal stem cells.
|title=Frailty index as a predictor of mortality: a systematic review and meta-analysis.
|date=07.2018
|date=01.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29804242
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29040347
|full-text-url=https://sci-hub.do/10.1007/s10522-018-9757-5
|full-text-url=https://sci-hub.do/10.1093/ageing/afx162
}}
}}
* {{medline-title
* {{medline-title
|title=Ascorbic acid inhibits senescence in mesenchymal stem cells through ROS and AKT/mTOR signaling.
|title=Trajectories of IGF-I Predict Mortality in Older Adults: The Cardiovascular Health Study.
|date=10.2018
|date=14.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29777434
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28977343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214856
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001890
}}
}}
* {{medline-title
* {{medline-title
|title=Co-Administration of Melatonin Effectively Enhances the Therapeutic Effects of Pioglitazone on Mesenchymal Stem Cells Undergoing Indoxyl Sulfate-Induced Senescence through Modulation of Cellular Prion Protein Expression.
|title=Is orthostatic hypotension more common in individuals with atrial fibrillation?-Findings from The Irish Longitudinal Study on Ageing (TILDA).
|date=04.05.2018
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29734669
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28985288
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983612
|full-text-url=https://sci-hub.do/10.1093/ageing/afx096
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in phenotype and differentiation potential of human mesenchymal stem cells aging in vitro.
|title=Subjective life expectancy is a risk factor for perceived health status and mortality.
|date=11.05.2018
|date=02.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751774
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28969645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948736
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625600
}}
}}
* {{medline-title
* {{medline-title
|title=Improvement of Cell Cycle Lifespan and Genetic Damage Susceptibility of Human Mesenchymal Stem Cells by Hypoxic Priming.
|title=The effects of dexmedetomidine preconditioning on aged rat heart of ischaemia reperfusion injury.
|date=30.05.2018
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29699381
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28987955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984059
|full-text-url=https://sci-hub.do/10.1016/j.rvsc.2017.09.028
}}
}}
* {{medline-title
* {{medline-title
|title=Aging impairs beige adipocyte differentiation of mesenchymal stem cells via the reduced expression of Sirtuin 1.
|title=Diabetes and Deficits in Cortical Bone Density, Microarchitecture, and Bone Size: Framingham [[HR]]-pQCT Study.
|date=07.06.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29678576
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28929525
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.04.136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771832
}}
}}
* {{medline-title
* {{medline-title
|title=GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling.
|title=Gender differences in longevity in free-living older adults who eat-with-others: a prospective study in Taiwan.
|date=07.2018
|date=18.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29694926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928182
|full-text-url=https://sci-hub.do/10.1016/j.bone.2018.04.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623554
}}
}}
* {{medline-title
* {{medline-title
|title=Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis.
|title=Decline in effort capacity with age: Echocardiographic stress analysis in the elderly.
|date=06.04.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29642406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28921674
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923408
|full-text-url=https://sci-hub.do/10.1111/echo.13709
}}
}}
* {{medline-title
* {{medline-title
|title=Dysfunction of Mesenchymal Stem Cells Isolated from Metabolic Syndrome and Type 2 Diabetic Patients as Result of Oxidative Stress and Autophagy may Limit Their Potential Therapeutic Use.
|title=Impaired disengagement of attention and its relationship to emotional distress in infants at high-risk for autism spectrum disorder.
|date=06.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29611042
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28914144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960487
|full-text-url=https://sci-hub.do/10.1080/13803395.2017.1372368
}}
}}
* {{medline-title
* {{medline-title
|title=Isolating Pediatric Mesenchymal Stem Cells with Enhanced Expansion and Differentiation Capabilities.
|title=Statins for Primary Prevention of Cardiovascular Events and Mortality in Older Men.
|date=06.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29631483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28892121
|full-text-url=https://sci-hub.do/10.1089/ten.TEC.2018.0031
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681374
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal stem cell transplantation in systemic lupus erythematous, a mesenchymal stem cell disorder.
|title=Galectin-3 and risk of ischaemic stroke: Reasons for Geographic and Racial Differences in Stroke cohort.
|date=06.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29631514
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28872212
|full-text-url=https://sci-hub.do/10.1177/0961203318768889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008611
}}
}}
* {{medline-title
* {{medline-title
|title=A brain-age model for preterm infants based on functional connectivity.
|title=Sleep duration, mortality and the influence of age.
|date=26.04.2018
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28856478
|full-text-url=https://sci-hub.do/10.1088/1361-6579/aabac4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680380
}}
}}
* {{medline-title
* {{medline-title
|title=Diabetic serum from older women increases adipogenic differentiation in mesenchymal stem cells.
|title=Comparison of yoga and walking-exercise on cardiac time intervals as a measure of cardiac function in elderly with increased pulse pressure.
|date=08.2018
|date=07-08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29521566
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062440
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560911
}}
}}
* {{medline-title
* {{medline-title
|title=Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan.
|title=Dietary acid load and renal function have varying effects on blood acid-base status and exercise performance across age and sex.
|date=31.03.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825967
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881094
|full-text-url=https://sci-hub.do/10.1139/apnm-2017-0279
}}
}}
* {{medline-title
* {{medline-title
|title=Automated image analysis detects aging in clinical-grade mesenchymal stromal cell cultures.
|title=Elite Distance Runners: A 45-Year Follow-up.
|date=10.01.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29321040
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817510
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763576
|full-text-url=https://sci-hub.do/10.1249/MSS.0000000000001407
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal Stem Cells Secretory Responses: Senescence Messaging Secretome and Immunomodulation Perspective.
|title=Short-term water-based aerobic training promotes improvements in aerobic conditioning parameters of mature women.
|date=2017
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312442
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28779920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742268
|full-text-url=https://sci-hub.do/10.1016/j.ctcp.2017.06.001
}}
* {{medline-title
|title=Glutathione Peroxidase 3 Delivered by hiPSC-[[MSC]]s Ameliorated Hepatic IR Injury via Inhibition of Hepatic Senescence.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29290803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743470
}}
}}
* {{medline-title
* {{medline-title
|title=Graft-Versus-Host Disease Amelioration by Human Bone Marrow Mesenchymal Stromal/Stem Cell-Derived Extracellular Vesicles Is Associated with Peripheral Preservation of Naive T Cell Populations.
|title=Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study.
|date=03.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29239062
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28754803
|full-text-url=https://sci-hub.do/10.1002/stem.2759
|full-text-url=https://sci-hub.do/10.1136/annrheumdis-2016-210767
}}
}}
* {{medline-title
* {{medline-title
|title=Orthogonal potency analysis of mesenchymal stromal cell function during ex vivo expansion.
|title=Impact of persistence and non-persistence in leisure time physical activity on coronary heart disease and all-cause mortality: The Copenhagen City Heart Study.
|date=01.01.2018
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29137914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28728482
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741495
|full-text-url=https://sci-hub.do/10.1177/2047487317721021
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of Age on Human Adipose Stem Cells for Bone Tissue Engineering.
|title=The Frequency-Dependent Aerobic Exercise Effects of Hypothalamic GABAergic Expression and Cardiovascular Functions in Aged Rats.
|date=09.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29113460
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28713263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491914
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related Changes in Bone Marrow Mesenchymal Stromal Cells: A Potential Impact on Osteoporosis and Osteoarthritis Development.
|title=Frequency of frailty and its association with cognitive status and survival in older Chileans.
|date=09.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29113463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28721027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680949
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498773
}}
}}
* {{medline-title
* {{medline-title
|title=Restoring the quantity and quality of elderly human mesenchymal stem cells for autologous cell-based therapies.
|title=End-stage renal disease versus death in a Portuguese cohort of elderly patients: an approach using competing event analysis.
|date=27.10.2017
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29078802
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28729248
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658952
|full-text-url=https://sci-hub.do/10.1136/jim-2017-000480
}}
}}
* {{medline-title
* {{medline-title
|title=Decoy TRAIL receptor CD264: a cell surface marker of cellular aging for human bone marrow-derived mesenchymal stem cells.
|title=Reproducibility of 24-h heart rate variability in children.
|date=29.09.2017
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28962588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28667574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622446
|full-text-url=https://sci-hub.do/10.1007/s10286-017-0445-3
}}
}}
* {{medline-title
* {{medline-title
|title=Allogeneic Mesenchymal Stem Cells Ameliorate Aging Frailty: A Phase II Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
|title=Heritability of resting heart rate and association with mortality in middle-aged and elderly twins.
|date=12.10.2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28977399
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28637897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861900
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831408
}}
}}
* {{medline-title
* {{medline-title
|title=Long noncoding RNA‑p21 modulates cellular senescence via the Wnt/β‑catenin signaling pathway in mesenchymal stem cells.
|title=Diabetes mellitus: a risk factor for seizures in the elderly-a population-based study.
|date=11.2017
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28901439
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28631057
|full-text-url=https://sci-hub.do/10.3892/mmr.2017.7430
|full-text-url=https://sci-hub.do/10.1007/s00592-017-1011-0
}}
}}
* {{medline-title
* {{medline-title
|title=Reduced neuroprotective potential of the mesenchymal stromal cell secretome with ex vivo expansion, age and progressive multiple sclerosis.
|title=Age Modulates Physiological Responses during Fan Use under Extreme Heat and Humidity.
|date=01.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28917625
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28609330
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758344
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645224
}}
}}
* {{medline-title
* {{medline-title
|title=Lactoferrin Protects Human Mesenchymal Stem Cells from Oxidative Stress-Induced Senescence and Apoptosis.
|title=Dental Status and Compression of Life Expectancy with Disability.
|date=28.10.2017
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28870012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28605598
|full-text-url=https://sci-hub.do/10.4014/jmb.1707.07040
|full-text-url=https://sci-hub.do/10.1177/0022034517713166
}}
}}
* {{medline-title
* {{medline-title
|title=Methylome Analysis of Human Bone Marrow [[MSC]]s Reveals Extensive Age- and Culture-Induced Changes at Distal Regulatory Elements.
|title=Bone microstructure in men assessed by [[HR]]-pQCT: Associations with risk factors and differences between men with normal, low, and osteoporosis-range areal BMD.
|date=12.09.2017
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28844656
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28580402
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440848
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of sulfur mustard on mesenchymal stem cells.
|title=Motor function and incident dementia: a systematic review and meta-analysis.
|date=01.09.2018
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28818580
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28541374
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2017.08.008
|full-text-url=https://sci-hub.do/10.1093/ageing/afx084
}}
}}
* {{medline-title
* {{medline-title
|title=Concise Review: Musculoskeletal Stem Cells to Treat Age-Related Osteoporosis.
|title=Effects of resistance training frequency on cardiorespiratory fitness in older men and women during intervention and follow-up.
|date=10.2017
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28834263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28526625
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430063
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.05.012
}}
}}
* {{medline-title
* {{medline-title
|title=Microvesicles as Potential Biomarkers for the Identification of Senescence in Human Mesenchymal Stem Cells.
|title=Effect of High-Salt Diet on Age-Related High Blood Pressure and Hypothalamic Redox Signaling.
|date=2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28819455
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28521325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558561
|full-text-url=https://sci-hub.do/10.1159/000472259
}}
}}
* {{medline-title
* {{medline-title
|title=Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function.
|title=Cardiorespiratory responses and myocardial function within incremental exercise in healthy unmedicated older vs. young men and women.
|date=12.09.2017
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28781075
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28523609
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599186
|full-text-url=https://sci-hub.do/10.1007/s40520-017-0776-x
}}
}}
* {{medline-title
* {{medline-title
|title=IFN-γ induces senescence-like characteristics in mouse bone marrow mesenchymal stem cells.
|title=Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies.
|date=03-04.2017
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791835
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28501495
|full-text-url=https://sci-hub.do/10.17219/acem/61431
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555438
}}
}}
==BDNF==
* {{medline-title
* {{medline-title
|title=Influence of [i][[BDNF]][/i] Genetic Polymorphisms in the Pathophysiology of Aging-related Diseases.
|title=Changes in time spent walking and the risk of incident dementia in older Japanese people: the Ohsaki Cohort 2006 Study.
|date=12.2020
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33269104
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28475691
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673859
|full-text-url=https://sci-hub.do/10.1093/ageing/afx078
}}
}}
* {{medline-title
* {{medline-title
|title=Moderators of the Impact of (Poly)Phenols Interventions on Psychomotor Functions and [[BDNF]]: Insights from Subgroup Analysis and Meta-Regression.
|title=Buccal telomere length and its associations with cortisol, heart rate variability, heart rate, and blood pressure responses to an acute social evaluative stressor in college students.
|date=19.09.2020
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32961777
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28482730
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551086
|full-text-url=https://sci-hub.do/10.1080/10253890.2017.1328494
}}
}}
* {{medline-title
* {{medline-title
|title=Astroglia-Derived [[BDNF]] and MSK-1 Mediate Experience- and Diet-Dependent Synaptic Plasticity.
|title=Models describing metronidazole pharmacokinetics in relation to hemodynamics in turkeys.
|date=18.07.2020
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32708382
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28454000
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407492
|full-text-url=https://sci-hub.do/10.1016/j.rvsc.2017.03.014
}}
}}
* {{medline-title
* {{medline-title
|title=[[BDNF]] reverses aging-related microglial activation.
|title=Hearing Loss and Risk of Mild Cognitive Impairment and Dementia: Findings from the Singapore Longitudinal Ageing Study.
|date=14.07.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32664974
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28420004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362451
|full-text-url=https://sci-hub.do/10.1159/000464281
}}
}}
* {{medline-title
* {{medline-title
|title=High Supervised Resistance Training in Elderly Women: The Role of Supervision Ratio.
|title=Assessment of effects of differences in trunk posture during Fowler's position on hemodynamics and cardiovascular regulation in older and younger subjects.
|date=2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32509119
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28408809
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241618
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384695
}}
}}
* {{medline-title
* {{medline-title
|title=Metformin regulates astrocyte reactivity in Parkinson's disease and normal aging.
|title=Age-related effects on markers of inflammation and cartilage metabolism in response to an intra-articular lipopolysaccharide challenge in horses.
|date=15.09.2020
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32497590
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28380609
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2020.108173
|full-text-url=https://sci-hub.do/10.2527/jas.2016.1078
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction.
|title=Association of mortality and phase angle measured by different bioelectrical impedance analysis (BIA) devices.
|date=05.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32489703
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28381339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220283
|full-text-url=https://sci-hub.do/10.1016/j.clnu.2017.03.023
}}
}}
* {{medline-title
* {{medline-title
|title=The Role of [[BDNF]] on Aging-Modulation Markers.
|title=Circulating Vitamin K Is Inversely Associated with Incident Cardiovascular Disease Risk among Those Treated for Hypertension in the Health, Aging, and Body Composition Study (Health ABC).
|date=09.05.2020
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32397504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287884
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404216
}}
}}
* {{medline-title
* {{medline-title
|title=Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice.
|title=Recombinant cells in the lung increase with age via de novo recombination events and clonal expansion.
|date=08.04.2020
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268299
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28370323
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}}
* {{medline-title
* {{medline-title
|title=Microglia senescence occurs in both substantia nigra and ventral tegmental area.
|title=Caregiving, volunteering or both? Comparing effects on health and mortality using census-based records from almost 250,000 people aged 65 and over.
|date=11.2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32275335
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* {{medline-title
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|title=Towards an understanding of the physical activity-[[BDNF]]-cognition triumvirate: A review of associations and dosage.
|title=Sense of life worth living (ikigai) and incident functional disability in elderly Japanese: The Tsurugaya Project.
|date=07.2020
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}}
* {{medline-title
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|title=Impact of [[BDNF]] and sex on maintaining intact memory function in early midlife.
|title=Effect of age and gender on serum periostin: Relationship to cortical measures, bone turnover and hormones.
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}}
* {{medline-title
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|title=Testosterone replacement causes dose-dependent improvements in spatial memory among aged male rats.
|title=Cross-sectional Versus Longitudinal Change in a Prospective [[HR]]-pQCT Study.
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* {{medline-title
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|title=The effects of aerobic exercise intensity on memory in older adults.
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}}
* {{medline-title
* {{medline-title
|title=Protective effects of vitamin D on neurophysiologic alterations in brain aging: role of brain-derived neurotrophic factor ([[BDNF]]).
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}}
* {{medline-title
* {{medline-title
|title=Differential Effects of Physical Exercise, Cognitive Training, and Mindfulness Practice on Serum [[BDNF]] Levels in Healthy Older Adults: A Randomized Controlled Intervention Study.
|title=Complications during hospitalization and risk factors in elderly patients with hip fracture following integrated orthogeriatric treatment.
|date=2019
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* {{medline-title
* {{medline-title
|title=Dietary Supplementation with Fish Oil or Conjugated Linoleic Acid Relieves Depression Markers in Mice by Modulation of the Nrf2 Pathway.
|title=Alcoholic beverage preference and diabetes incidence across Europe: the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) project.
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* {{medline-title
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|date=01-03.2020
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* {{medline-title
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|title=URB597 ameliorates the deleterious effects induced by binge alcohol consumption in adolescent rats.
|title=No increased risk of cardiovascular events in older adults initiating dipeptidyl peptidase-4 inhibitors vs therapeutic alternatives.
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}}
* {{medline-title
* {{medline-title
|title=Pro-neurocognitive and anti-sarcopenic benefits of one-year metformin therapy in ovariectomized aged mice.
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}}
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|title=Ellagic acid dose and time-dependently abrogates d-galactose-induced animal model of aging: Investigating the role of PPAR-γ.
|title=Physical inactivity is a strong risk factor for stroke in the oldest old: Findings from a multi-ethnic population (the Northern Manhattan Study).
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}}
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|title=Astrocyte Function Is Affected by Aging and Not Alzheimer's Disease: A Preliminary Investigation in Hippocampi of 3xTg-AD Mice.
|title=Cognitive Decline, Body Mass Index, and Waist Circumference in Community-Dwelling Elderly Participants.
|date=2019
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}}
* {{medline-title
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|title=Exenatide Reverts the High-Fat-Diet-Induced Impairment of [[BDNF]] Signaling and Inflammatory Response in an Animal Model of Alzheimer's Disease.
|title=Maximal heart rate declines linearly with age independent of cardiorespiratory fitness levels.
|date=2019
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}}
* {{medline-title
* {{medline-title
|title=The Impact of Physical Exercise on Brain-Derived Neurotrophic Factor ([[BDNF]]) Level in Elderly Population.
|title=Age-Associated ALU Element Instability in White Blood Cells Is Linked to Lower Survival in Elderly Adults: A Preliminary Cohort Study.
|date=31.05.2019
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28060910
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}}
* {{medline-title
* {{medline-title
|title=Cardioprotective effects of microRNA-18a on acute myocardial infarction by promoting cardiomyocyte autophagy and suppressing cellular senescence via brain derived neurotrophic factor.
|title=Cortical porosity exhibits accelerated rate of change in peri- compared with post-menopausal women.
|date=2019
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168354
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28074250
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}}
* {{medline-title
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|title=Exercise enhances the expression of brain-derived neurotrophic factor in the hippocampus accompanied by epigenetic alterations in senescence-accelerated mice prone 8.
|title=Aging impairs double-strand break repair by homologous recombination in Drosophila germ cells.
|date=27.07.2019
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}}
* {{medline-title
* {{medline-title
|title=Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
|title=Age-related reference curves of volumetric bone density, structure, and biomechanical parameters adjusted for weight and height in a population of healthy women: an [[HR]]-pQCT study.
|date=09.2019
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}}
* {{medline-title
* {{medline-title
|title=Gross Motor Skills Training Leads to Increased Brain-Derived Neurotrophic Factor Levels in Healthy Older Adults: A Pilot Study.
|title=Cortical Bone Area Predicts Incident Fractures Independently of Areal Bone Mineral Density in Older Men.
|date=2019
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31031639
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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473056
|full-text-url=https://sci-hub.do/10.1210/jc.2016-3177
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}}
* {{medline-title
* {{medline-title
|title=Dysregulation of the SNARE-binding protein Munc18-1 impairs [[BDNF]] secretion and synaptic neurotransmission: a novel interventional target to protect the aging brain.
|title=The Power of Serum Uric Acid in Predicting Metabolic Syndrome Diminishes With Age in an Elderly Chinese Population.
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|full-text-url=https://sci-hub.do/10.1007/s12603-015-0633-6
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}}
* {{medline-title
* {{medline-title
|title=Frailty biomarkers in humans and rodents: Current approaches and future advances.
|title=Age- and Sex-Dependent Changes of Intra-articular Cortical and Trabecular Bone Structure and the Effects of Rheumatoid Arthritis.
|date=06.2019
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002925
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27787923
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|full-text-url=https://sci-hub.do/10.1002/jbmr.3025
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}}
* {{medline-title
* {{medline-title
|title=Pregnancies alters spine number in cortical and subcortical limbic brain regions of old rats.
|title=Paradoxical delay of senescence upon depletion of [[BRCA2]] in telomerase-deficient worms.
|date=08.2019
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* {{medline-title
* {{medline-title
|title=TrkB Activation during a Critical Period Mimics the Protective Effects of Early Visual Experience on Perception and the Stability of Receptive Fields in Adult Superior Colliculus.
|title=Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence.
|date=05.06.2019
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}}
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* {{medline-title
|title=Ageing of the somatosensory system at the periphery: age-related changes in cutaneous mechanoreceptors.
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}}
* {{medline-title
* {{medline-title
|title=Hydrophilic Glycoproteins of an Edible Green Alga [i]Capsosiphon fulvescens[/i] Prevent Aging-Induced Spatial Memory Impairment by Suppressing GSK-3β-Mediated ER Stress in Dorsal Hippocampus.
|title=Characterization of Activity and Cardiovascular Responses During Surfing in Recreational Male Surfers Between the Ages of 18 and 75 Years Old.
|date=15.03.2019
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30875947
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27623020
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|full-text-url=https://sci-hub.do/10.1123/japa.2016-0041
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}}
* {{medline-title
* {{medline-title
|title=β-Alanine supplementation reduces anxiety and increases neurotrophin expression in both young and older rats.
|title=Socioeconomic correlates of quality of life for non-Māori in advanced age: Te Puāwaitanga o Nga Tapuwae Kia ora Tonu. Life and Living in Advanced Age: a Cohort Study in New Zealand (LiLACS NZ).
|date=02.2019
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27607082
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* {{medline-title
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|title=Structural and molecular correlates of cognitive aging in the rat.
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}}
* {{medline-title
* {{medline-title
|title=Reduction of [[BDNF]] results in GABAergic neuroplasticity dysfunction and contributes to late-life anxiety disorder.
|title=Consequences of mating and predation risk for longevity in a freshwater snail: abstinence makes the heart beat longer.
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|title=The Role of Enhanced Cognition to Counteract Detrimental Effects of Prolonged Bed Rest: Current Evidence and Perspectives.
|title=Investigation of risk factors for mortality in aged guide dogs: A retrospective cohort study.
|date=2018
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|title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.
|title=Age-Related Sensory Impairments and Risk of Cognitive Impairment.
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* {{medline-title
|title=The TrkB-T1 receptor mediates [[BDNF]]-induced migration of aged cardiac microvascular endothelial cells by recruiting Willin.
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* {{medline-title
* {{medline-title
|title=Influence of [[BDNF]] Val66Met on the relationship between cardiorespiratory fitness and memory in cognitively normal older adults.
|title=Baseline, Time-Updated, and Cumulative HIV Care Metrics for Predicting Acute Myocardial Infarction and All-Cause Mortality.
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|title=Hypothalamic gene transfer of [[BDNF]] promotes healthy aging in mice.
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|title=Sex-dependent effect of the [[BDNF]] Val66Met polymorphism on executive functioning and processing speed in older adults: evidence from the health ABC study.
|title=Effect of floorball training on blood lipids, body composition, muscle strength, and functional capacity of elderly men.
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|title=Brain-Derived Neurotrophic Factor and Its Associations with Metabolism and Physical Activity in a Latino Sample.
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* {{medline-title
* {{medline-title
|title=Exercise training increases cardiac, hepatic and circulating levels of brain-derived neurotrophic factor and irisin in young and aged rats.
|title=Nutrition and mortality in the elderly over 10 years of follow-up: the Three-City study.
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|title=RbAp48 Protein Is a Critical Component of [[GPR158]]/OCN Signaling and Ameliorates Age-Related Memory Loss.
|title=Omega-3 polyunsaturated fatty acid supplementation attenuates blood pressure increase at onset of isometric handgrip exercise in healthy young and older humans.
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}}
* {{medline-title
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|title=[[BDNF]] trafficking and signaling impairment during early neurodegeneration is prevented by moderate physical activity.
|title=Dietary flavonoid intake and risk of incident depression in midlife and older women.
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* {{medline-title
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|title=Walnut diets up-regulate the decreased hippocampal neurogenesis and age-related cognitive dysfunction in d-galactose induced aged rats.
|title=Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans.
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|title=Genetics of stroke recovery: [[BDNF]] val66met polymorphism in stroke recovery and its interaction with aging.
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* {{medline-title
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|title=Is Objectively Assessed Sedentary Behavior, Physical Activity and Cardiorespiratory Fitness Linked to Brain Plasticity Outcomes in Old Age?
|title=Do BRCA1/2 mutation carriers have an earlier onset of natural menopause?
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|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=The pathophysiologic mechanisms associated with hypotensive susceptibility.
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|title=Remodeling of myelinated fibers and internal capillaries in distal peripheral nerves following aerobic exercise in aged rats.
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|title=The Moderating Role of [[COMT]] and [[BDNF]] Polymorphisms on Transfer Effects Following Multi- and Single-Domain Cognitive Training Among Community-Dwelling Shanghainese Older Adults.
|title=Does cytomegalovirus infection contribute to socioeconomic disparities in all-cause mortality?
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|title=Soybean-Derived Glycine-Arginine Dipeptide Administration Promotes Neurotrophic Factor Expression in the Mouse Brain.
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|title=Brain-derived neurotrophic factor in serum as an animal welfare indicator of environmental enrichment in pigs.
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* {{medline-title
* {{medline-title
|title=Exercise Training Protects Against Aging-Induced Cognitive Dysfunction via Activation of the Hippocampal [[PGC]]-1α/[[FNDC5]]/[[BDNF]] Pathway.
|title=Parity and Oral Contraceptive Use in Relation to Ovarian Cancer Risk in Older Women.
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|title=The influence of aging on the methylation status of brain-derived neurotrophic factor gene in blood.
|title=Social participation and mortality: does social position in civic groups matter?
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|title=Surgical Trauma Exacerbates Cognitive Deficits and Neuroinflammation in Aged Rats: The Role of [[CX3CL1]]-[[CX3CR1]] Signaling.
|title=Decreased glomerular filtration rate estimated by 2009 CKD-EPI equation predicts mortality in older hip fracture population.
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|title=Objectively Verified Parental Hip Fracture Is an Independent Risk Factor for Fracture: a Linkage Analysis of 478,792 Parents and 261,705 Offspring.
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|title=Aerobic exercise upregulates the [[BDNF]]-Serotonin systems and improves the cognitive function in rats.
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|title=Quantitative Scheimpflug camera study of the lens density in healthy Turkish population.
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|title=An acute bout of aerobic or strength exercise specifically modifies circulating exerkine levels and neurocognitive functions in elderly individuals with mild cognitive impairment.
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|title=Metformin ameliorates the age-related changes of d-galactose administration in ovariectomized mice.
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|title=GPR30 activation improves memory and facilitates DHPG-induced LTD in the hippocampal [[CA3]] of middle-aged mice.
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|title=Exenatide exerts cognitive effects by modulating the [[BDNF]]-TrkB neurotrophic axis in adult mice.
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|title=Candidate molecular pathways of white matter vulnerability in the brain of normal aging rhesus monkeys.
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|full-text-url=https://sci-hub.do/10.1080/13607863.2017.1421615
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603571
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}}
* {{medline-title
* {{medline-title
|title=A noradrenergic lesion aggravates the effects of systemic inflammation on the hippocampus of aged rats.
|title=The Association of Reproductive Hormone Levels and All-Cause, Cancer, and Cardiovascular Disease Mortality in Men.
|date=2017
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29261743
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|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|title=Advanced Age, High β-CTX Levels, and Impaired Renal Function are Independent Risk Factors for All-Cause One-Year Mortality in Hip Fracture Patients.
|date=2017
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
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* {{medline-title
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|title=Effects of cerebrolysin on nerve growth factor system in the aging rat brain.
|title=Aging augments renal vasoconstrictor response to orthostatic stress in humans.
|date=2017
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* {{medline-title
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|title=Repeated exposure to sevoflurane impairs the learning and memory of older male rats.
|title=The [[SIRT1]] promoter polymorphic site rs12778366 increases IL-6 related human mortality in the prospective study "Treviso Longeva (TRELONG)".
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* {{medline-title
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|title=Interaction between [i][[BDNF]][/i] Polymorphism and Physical Activity on Inhibitory Performance in the Elderly without Cognitive Impairment.
|title=Sleeve Gastrectomy Decreases Body Weight, Whole-Body Adiposity, and Blood Pressure Even in Aged Diet-Induced Obese Rats.
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* {{medline-title
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|title=Exercise enhances cognitive function and neurotrophin expression in the hippocampus accompanied by changes in epigenetic programming in senescence-accelerated mice.
|title=Associations of obesity and body fat distribution with incident atrial fibrillation in the biracial health aging and body composition cohort of older adults.
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}}
* {{medline-title
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|title=Age-related changes in STriatal-Enriched protein tyrosine Phosphatase levels: Regulation by [[BDNF]].
|title=Food Habits, Lifestyle Factors and Mortality among Oldest Old Chinese: The Chinese Longitudinal Healthy Longevity Survey (CLHLS).
|date=01.2018
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* {{medline-title
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|title=Brain-Derived Neurotrophic Factor in Patients with Primary Open-Angle Glaucoma and Age-related Cataract.
|title=Age- and Gender-related Disparities in Primary Percutaneous Coronary Interventions for Acute ST-segment elevation Myocardial Infarction.
|date=02.2018
|date=2015
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* {{medline-title
* {{medline-title
|title=Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of [[BDNF]]/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
|title=Functional measures, inflammatory markers and endothelin-1 as predictors of 360-day survival in centenarians.
|date=06.03.2018
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|title=Protective effect of xanthohumol against age-related brain damage.
|title=Low-frequency oscillations in cerebrovascular and cardiovascular hemodynamics: Their interrelationships and the effect of age.
|date=11.2017
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* {{medline-title
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|title=Effects of aerobic exercise on brain metabolism and grey matter volume in older adults: results of the randomised controlled SMART trial.
|title=Testing a modified perceived exertion scale for Alzheimer's disease.
|date=18.07.2017
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28934191
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* {{medline-title
* {{medline-title
|title=Differential deregulation of [[NGF]] and [[BDNF]] neurotrophins in a transgenic rat model of Alzheimer's disease.
|title=High Cardiorespiratory Fitness Levels Slow the Decline in Peak Heart Rate with Age.
|date=12.2017
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28865749
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26258854
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2017.08.019
|full-text-url=https://sci-hub.do/10.1249/MSS.0000000000000745
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}}
* {{medline-title
* {{medline-title
|title=Walking speed decline in older adults is associated with elevated pro-[[BDNF]] in plasma extracellular vesicles.
|title=Sex and age effects on cardiovascular autonomic function in healthy adults.
|date=11.2017
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28843509
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|full-text-url=https://sci-hub.do/10.1007/s10286-015-0310-1
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}}
* {{medline-title
* {{medline-title
|title=Exercise training with concomitant nitric oxide synthase inhibition improved anxiogenic behavior, spatial cognition, and [[BDNF]]/P70S6 kinase activation in 20-month-old rats.
|title=Role of endocortical contouring methods on precision of [[HR]]-pQCT-derived cortical micro-architecture in postmenopausal women and young adults.
|date=01.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854337
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|full-text-url=https://sci-hub.do/10.1139/apnm-2017-0313
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* {{medline-title
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|title=Chronic fluoxetine ameliorates adolescent chronic nicotine exposure-induced long-term adult deficits in trace conditioning.
|title=History of previous bleeding and C-reactive protein improve assessment of bleeding risk in elderly patients (≥ 80 years) with myocardial infarction.
|date=10.2017
|date=11.2015
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|title=Spontaneous physical activity and mediators of energy homeostasis in the hypothalamus of mice from 4 to 10 months of age.
|title=Use of serum albumin and activities of daily living to predict mortality in long-lived individuals over 95 years of age: a population-based study.
|date=01.11.2017
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28786537
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|full-text-url=https://sci-hub.do/10.1113/EP086265
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}}
==CA1==
* {{medline-title
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|title=The relation between tau pathology and granulovacuolar degeneration of neurons.
|title=Pyridostigmine enhances atrial tachyarrhythmias in aging spontaneously hypertensive rats.
|date=01.2021
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|title=Memory and dendritic spines loss, and dynamic dendritic spines changes are age-dependent in the rat.
|title=Low heel ultrasound parameters predict mortality in men: results from the European Male Ageing Study (EMAS).
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* {{medline-title
|title=Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis.
|title=Regulation of Cardiac Autonomic Nervous System Control across Frailty Statuses: A Systematic Review.
|date=04.09.2020
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|title=COX5A Plays a Vital Role in Memory Impairment Associated With Brain Aging [i]via[/i] the BDNF/ERK1/2 Signaling Pathway.
|title=Anti-mullerian hormone ([[AMH]]) is associated with natural menopause in a population-based sample: The CARDIA Women's Study.
|date=2020
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* {{medline-title
|title=Changes of fat-mass and obesity-associated protein expression in the hippocampus in animal models of high-fat diet-induced obesity and D-galactose-induced aging.
|title=Dose-dependent effect of androgen deprivation therapy for localized prostate cancer on adverse cardiac events.
|date=2020
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|full-text-url=https://sci-hub.do/10.1111/bju.13203
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* {{medline-title
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|title=Phenylbutyrate ameliorates prefrontal cortex, hippocampus, and nucleus accumbens neural atrophy as well as synaptophysin and GFAP stress in aging mice.
|title=Ischemic heart disease, prescription of optimal medical therapy and geriatric syndromes in community-dwelling older men: A population-based study.
|date=11.2020
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|title=Heterogeneity in brain distribution of activated microglia and astrocytes in a rat ischemic model of Alzheimer's disease after 2 years of survival.
|title=Gait characteristics and sensory abilities of older adults are modulated by gender.
|date=05.06.2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32501292
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|full-text-url=https://sci-hub.do/10.1016/j.gaitpost.2015.04.002
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}}
* {{medline-title
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|title=Hippocampal Subregion Transcriptomic Profiles Reflect Strategy Selection during Cognitive Aging.
|title=Severity of depressive symptoms as a predictor of mortality: the English longitudinal study of ageing.
|date=17.06.2020
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}}
* {{medline-title
* {{medline-title
|title=Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan: A 7 T imaging study.
|title=Higher Intake of Fruit, but Not Vegetables or Fiber, at Baseline Is Associated with Lower Risk of Becoming Overweight or Obese in Middle-Aged and Older Women of Normal BMI at Baseline.
|date=05.05.2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32371923
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}}
* {{medline-title
* {{medline-title
|title=Laminarin Pretreatment Provides Neuroprotection against Forebrain Ischemia/Reperfusion Injury by Reducing Oxidative Stress and Neuroinflammation in Aged Gerbils.
|title=Effect of a community intervention programme promoting social interactions on functional disability prevention for older adults: propensity score matching and instrumental variable analyses, JAGES Taketoyo study.
|date=15.04.2020
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}}
* {{medline-title
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|title=Age-dependent Alteration in Mitochondrial Dynamics and Autophagy in Hippocampal Neuron of Cannabinoid CB1 Receptor-deficient Mice.
|title=Comparison of cyclic and impact-based reference point indentation measurements in human cadaveric tibia.
|date=07.2020
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}}
* {{medline-title
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|title=Functional Connectivity of Hippocampal CA3 Predicts Neurocognitive Aging via [[CA1]]-Frontal Circuit.
|title=Association of dialysis with the risks of cancers.
|date=30.06.2020
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}}
* {{medline-title
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|title=Integration of qRT-PCR and Immunohistochemical Techniques for mRNA Expression and Localization of m1AChR in the Brain of Aging Rat.
|title=Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver.
|date=2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32219760
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|full-text-url=https://sci-hub.do/10.1007/978-1-0716-0471-7_23
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}}
* {{medline-title
* {{medline-title
|title=Role of Eclipta prostrata extract in improving spatial learning and memory deficits in D-galactose-induced aging in rats.
|title=Higher circulating adiponectin levels are associated with increased risk of atrial fibrillation in older adults.
|date=10.2019
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32186114
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25855796
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161822
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* {{medline-title
|title=Age-related changes in thirst, salt appetite, and arterial blood pressure in response to aldosterone-dexamethasone combination in rats.
|date=15.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25833938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436977
}}
}}
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|title=Differential annualized rates of hippocampal subfields atrophy in aging and future Alzheimer's clinical syndrome.
|title=Undertreatment of Men in Their Seventies with High-risk Nonmetastatic Prostate Cancer.
|date=06.2020
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|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32107063
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25813688
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.01.011
|full-text-url=https://sci-hub.do/10.1016/j.eururo.2014.12.026
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}}
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|title=Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1  stem cells from young donors.
|title=Anthropometric indices and dietary intake: prospective determinants of geriatric cognitive impairment?
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}}
* {{medline-title
* {{medline-title
|title=Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life.
|title='Carriers of variant luteinizing hormone (V-LH) among 1593 Baltic men have significantly higher serum LH'.
|date=09.01.2020
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|title=Memory Performance Correlates of Hippocampal Subfield Volume in Mild Cognitive Impairment Subtype.
|title=Impact of living alone on institutionalization and mortality: a population-based longitudinal study.
|date=2019
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|full-text-url=https://sci-hub.do/10.1093/eurpub/ckv052
}}
}}
* {{medline-title
* {{medline-title
|title=Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses.
|title=[Normal values for high-resolution anorectal manometry in a healthy women: effects of age and maternity].
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* {{medline-title
|title=Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice.
|title=A comparison of risperidone and haloperidol for the risk of ischemic stroke in the elderly: a propensity score-matched cohort analysis.
|date=16.12.2019
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* {{medline-title
|title=Long-term Memory Upscales Volume of Postsynaptic Densities in the Process that Requires Autophosphorylation of αCaMKII.
|title=Inhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity.
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}}
* {{medline-title
* {{medline-title
|title=PACAP27 mitigates an age-dependent hippocampal vulnerability to PGJ2-induced spatial learning deficits and neuroinflammation in mice.
|title=Conservation of pro-longevity genes among mammals.
|date=01.2020
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}}
* {{medline-title
* {{medline-title
|title=Inhibition of oxidative stress by testosterone improves synaptic plasticity in senescence accelerated mice.
|title=Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture risk in older adults: the Age, Gene/Environment Susceptibility Study.
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|title=Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
|title=Normal pediatric data for isovolumic acceleration at the lateral tricuspid valve annulus-a heart rate - dependent measure of right ventricular contractility.
|date=14.06.2018
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905772
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25039533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001893
|full-text-url=https://sci-hub.do/10.1111/echo.12681
}}
}}
* {{medline-title
* {{medline-title
|title=Aerobic exercise upregulates the [[BDNF]]-Serotonin systems and improves the cognitive function in rats.
|title=Higher orthostatic heart rate predicts mortality: The Irish Longitudinal Study on Ageing (TILDA).
|date=11.2018
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29800645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25034834
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2018.05.007
|full-text-url=https://sci-hub.do/10.1007/s40520-014-0261-8
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of calretinin and parvalbumin positive interneurones in the hippocampal [[CA1]] of aged Alzheimer's disease mice.
|title=Aging and CaMKII alter intracellular Ca2  transients and heart rhythm in Drosophila melanogaster.
|date=10.08.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29782955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25003749
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.05.027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4087024
}}
}}
* {{medline-title
* {{medline-title
|title=Long-Term Moderate Exercise Rescues Age-Related Decline in Hippocampal Neuronal Complexity and Memory.
|title=Do hassles mediate between life events and mortality in older men? Longitudinal findings from the VA Normative Aging Study.
|date=2018
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29734165
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24995936
|full-text-url=https://sci-hub.do/10.1159/000488589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253863
}}
}}
* {{medline-title
* {{medline-title
|title=Stereological Investigation of the Effects of Treadmill Running Exercise on the Hippocampal Neurons in Middle-Aged APP/PS1 Transgenic Mice.
|title=Survival analysis of breast cancer subtypes in patients with spinal metastases.
|date=2018
|date=01.09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29689723
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24979144
|full-text-url=https://sci-hub.do/10.3233/JAD-171017
|full-text-url=https://sci-hub.do/10.1097/BRS.0000000000000473
}}
}}
* {{medline-title
* {{medline-title
|title=Hippocampal Sclerosis in the Oldest Old: A Finnish Population-Based Study.
|title=Optimal management of colorectal liver metastases in older patients: a decision analysis.
|date=2018
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29614661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24961482
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900558
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487755
}}
}}
* {{medline-title
* {{medline-title
|title=Inosine improves cognitive function and decreases aging-induced oxidative stress and neuroinflammation in aged female rats.
|title=Examining physiological responses across different driving maneuvers during an on-road driving task: a pilot study comparing older and younger drivers.
|date=10.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29619603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24949653
|full-text-url=https://sci-hub.do/10.1007/s10787-018-0476-y
|full-text-url=https://sci-hub.do/10.1080/15389588.2014.933478
}}
* {{medline-title
|title=Rosa26-GFP direct repeat (RaDR-GFP) mice reveal tissue- and age-dependence of homologous recombination in mammals in vivo.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24901438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046920
}}
}}
* {{medline-title
* {{medline-title
|title=Dynamic SAP102 expression in the hippocampal subregions of rats and APP/PS1 mice of various ages.
|title=Association of total adiposity and computed tomographic measures of regional adiposity with incident cancer risk: a prospective population-based study of older adults.
|date=06.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29574717
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24869972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5979819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071344
}}
}}
* {{medline-title
* {{medline-title
|title=Characterizing the human hippocampus in aging and Alzheimer's disease using a computational atlas derived from ex vivo MRI and histology.
|title=Racial disparities in an aging population: the relationship between age and race in the management of African American men with high-risk prostate cancer.
|date=17.04.2018
|date=01.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29592955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24862107
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910869
|full-text-url=https://sci-hub.do/10.1016/j.jgo.2014.05.001
}}
}}
* {{medline-title
* {{medline-title
|title=Incomplete Hippocampal Inversion and Its Relationship to Hippocampal Subfield Volumes and Aging.
|title=Life expectancy following orbital exenteration.
|date=07.2018
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29575376
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24879806
|full-text-url=https://sci-hub.do/10.1111/jon.12509
|full-text-url=https://sci-hub.do/10.1136/bjophthalmol-2013-304436
}}
}}
* {{medline-title
* {{medline-title
|title=Protracted hippocampal development is associated with age-related improvements in memory during early childhood.
|title=Do age-disparate relationships drive HIV incidence in young women? Evidence from a population cohort in rural KwaZulu-Natal, South Africa.
|date=01.07.2018
|date=01.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518573
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24815854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949262
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097949
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent changes in vesicular glutamate transporter 1 and 2 expression in the gerbil hippocampus.
|title=Hippocampus and amygdala volumes in children and young adults at high-risk of schizophrenia: research synthesis.
|date=05.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29532891
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24794883
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928628
|full-text-url=https://sci-hub.do/10.1016/j.schres.2014.03.030
}}
}}
* {{medline-title
* {{medline-title
|title=PGE2-EP3 signaling exacerbates hippocampus-dependent cognitive impairment after laparotomy by reducing expression levels of hippocampal synaptic plasticity-related proteins in aged mice.
|title=Assessment of physical strain in younger and older subjects using heart rate and scalings of perceived exertion.
|date=10.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29488342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24761802
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490074
|full-text-url=https://sci-hub.do/10.1080/00140139.2014.910613
}}
}}
* {{medline-title
* {{medline-title
|title=Downregulated Nuclear Factor E2-Related Factor 2 (Nrf2) Aggravates Cognitive Impairments via Neuroinflammation and Synaptic Plasticity in the Senescence-Accelerated Mouse Prone 8 (SAMP8) Mouse: A Model of Accelerated Senescence.
|title=Episodic ozone exposure in adult and senescent Brown Norway rats: acute and delayed effect on heart rate, core temperature and motor activity.
|date=23.02.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29474348
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24779854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833362
|full-text-url=https://sci-hub.do/10.3109/08958378.2014.905659
}}
}}
* {{medline-title
* {{medline-title
|title=GPR30 activation improves memory and facilitates DHPG-induced LTD in the hippocampal [[CA3]] of middle-aged mice.
|title=Characterizing microarchitectural changes at the distal radius and tibia in postmenopausal women using [[HR]]-pQCT.
|date=03.2018
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29421611
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24781379
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2018.02.005
|full-text-url=https://sci-hub.do/10.1007/s00198-014-2719-0
}}
}}
* {{medline-title
* {{medline-title
|title=[[CA1]] pyramidal neuron gene expression mosaics in the Ts65Dn murine model of Down syndrome and Alzheimer's disease following maternal choline supplementation.
|title=Individual and spousal education, mortality and life expectancy in Switzerland: a national cohort study.
|date=04.2018
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29394516
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24764353
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874173
|full-text-url=https://sci-hub.do/10.1136/jech-2013-203714
}}
}}
* {{medline-title
* {{medline-title
|title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling.
|title=Association Between 6-Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease.
|date=2017
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24695552
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485950
}}
}}
* {{medline-title
* {{medline-title
|title=Long-term treadmill exercise improves memory impairment through restoration of decreased synaptic adhesion molecule 1/2/3 induced by transient cerebral ischemia in the aged gerbil hippocampus.
|title=Sleep duration and incidence of lung cancer in ageing men.
|date=03.2018
|date=31.03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29341891
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24684747
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.01.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229981
}}
}}
* {{medline-title
* {{medline-title
|title=Prenatal exposure to valproic acid alters the development of excitability in the postnatal rat hippocampus.
|title=Effect of aging on carotid baroreflex control of blood pressure and leg vascular conductance in women.
|date=03.2018
|date=15.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29309796
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24682393
|full-text-url=https://sci-hub.do/10.1016/j.neuro.2018.01.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024722
}}
}}
* {{medline-title
* {{medline-title
|title=Neurodevelopment and behavior in neonatal OXYS rats with genetically determined accelerated senescence.
|title=Physical activity in older men: longitudinal associations with inflammatory and hemostatic biomarkers, N-terminal pro-brain natriuretic peptide, and onset of coronary heart disease and mortality.
|date=15.02.2018
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29274882
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24635212
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2017.12.021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283726
}}
}}
* {{medline-title
* {{medline-title
|title=Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment.
|title=Predicting all-cause and cause-specific mortality by static and dynamic measurements of allostatic load: a 10-year population-based cohort study in Taiwan.
|date=2017
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29276487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24631353
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727020
|full-text-url=https://sci-hub.do/10.1016/j.jamda.2014.02.001
}}
}}
* {{medline-title
* {{medline-title
|title=Myelin changes at the early stage of 5XFAD mice.
|title=Contribution of Alzheimer disease to mortality in the United States.
|date=03.2018
|date=25.03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288735
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24598707
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2017.12.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962992
}}
}}
* {{medline-title
* {{medline-title
|title=DPP-4 inhibition with linagliptin ameliorates the progression of premature aging in klotho-/- mice.
|title=Physiological characteristics of an aging Olympic athlete.
|date=01.12.2017
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195509
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24598701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709858
|full-text-url=https://sci-hub.do/10.1249/MSS.0000000000000331
}}
}}
* {{medline-title
* {{medline-title
|title=Antioxidant action of grape seed polyphenols and aerobic exercise in improving neuronal number in the hippocampus is associated with decrease in lipid peroxidation and hydrogen peroxide in adult and middle-aged rats.
|title=Association of sex hormones, aging, and atrial fibrillation in men: the Framingham Heart Study.
|date=01.2018
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29174497
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24610804
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035016
}}
}}
* {{medline-title
* {{medline-title
|title=Local Inhibition of PERK Enhances Memory and Reverses Age-Related Deterioration of Cognitive and Neuronal Properties.
|title=A pooled analysis of waist circumference and mortality in 650,000 adults.
|date=17.01.2018
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196323
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24582192
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596193
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104704
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Chronic Administration of Resveratrol on Cognitive Performance during Aging Process in Rats.
|title=Hearing loss may be a non-motor feature of Parkinson's disease in older people in Taiwan.
|date=2017
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24506292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661096
|full-text-url=https://sci-hub.do/10.1111/ene.12378
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease.
|title=Cognitive performance and functional status are the major factors predicting survival of centenarians in Poland.
|date=01.2018
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29113959
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24509978
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863355
|full-text-url=https://sci-hub.do/10.1093/gerona/glu003
}}
}}
* {{medline-title
* {{medline-title
|title=Time of day but not aging regulates 5-HT  receptor binding sites in the hamster hippocampus.
|title=Vitamin D deficiency in elderly people in Swedish nursing homes is associated with increased mortality.
|date=01.01.2018
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29107707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24520134
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.10.057
|full-text-url=https://sci-hub.do/10.1530/EJE-13-0855
}}
}}
* {{medline-title
* {{medline-title
|title=Cytoarchitectonically-driven MRI atlas of nonhuman primate hippocampus: Preservation of subfield volumes in aging.
|title=Association between sex steroid levels and bone microarchitecture in men: the STRAMBO study.
|date=05.2019
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29072793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24471567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920786
|full-text-url=https://sci-hub.do/10.1210/jc.2013-3233
}}
}}
* {{medline-title
* {{medline-title
|title=Individual differences in associative memory among older adults explained by hippocampal subfield structure and function.
|title=Metabolomics signature improves the prediction of cardiovascular events in elderly subjects.
|date=07.11.2017
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29078387
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24468136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692588
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2013.10.029
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of [[BDNF]]/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
|title=Mortality in systemic sclerosis: lessons learned from population-based and observational cohort studies.
|date=06.03.2018
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29065194
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24441644
|full-text-url=https://sci-hub.do/10.1093/ntr/ntx157
|full-text-url=https://sci-hub.do/10.1097/BOR.0000000000000027
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils.
|title=BMI and all-cause mortality in older adults: a meta-analysis.
|date=09.2017
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29046699
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24452240
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645602
|full-text-url=https://sci-hub.do/10.3945/ajcn.113.068122
}}
}}
* {{medline-title
* {{medline-title
|title=Grape Seed Proanthocyanidin and Swimming Exercise Protects Against Cognitive Decline: A Study on M1 Acetylcholine Receptors in Aging Male Rat Brain.
|title=Gender-specific associations between physical functioning, bone quality, and fracture risk in older people.
|date=12.2017
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28993969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24458514
|full-text-url=https://sci-hub.do/10.1007/s11064-017-2406-6
|full-text-url=https://sci-hub.do/10.1007/s00223-013-9836-1
}}
}}
* {{medline-title
* {{medline-title
|title=Aging dependent effect of nuclear tau.
|title=Late-onset hypogonadism and mortality in aging men.
|date=15.12.2017
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28974363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24423283
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2017.09.030
|full-text-url=https://sci-hub.do/10.1210/jc.2013-2052
}}
}}
* {{medline-title
* {{medline-title
|title=Dopamine D4 receptor activation restores [[CA1]] LTP in hippocampal slices from aged mice.
|title=Effect of light-dark changes on the locomotor activity in open field in adult rats and opossums.
|date=12.2017
|date=11.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28975698
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24402750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676052
|full-text-url=https://sci-hub.do/10.5603/fm.2013.0050
}}
}}
* {{medline-title
* {{medline-title
|title=[[CA1]] pyramidal cells have diverse biophysical properties, affected by development, experience, and aging.
|title=Differential contribution of afferent and central pathways to the development of baroreflex dysfunction in chronic kidney disease.
|date=2017
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948109
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24379179
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609525
|full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.113.02110
}}
}}
* {{medline-title
* {{medline-title
|title=Temporal binding function of dorsal [[CA1]] is critical for declarative memory formation.
|title=Association of 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D and parathyroid hormone with mortality among middle-aged and older European men.
|date=19.09.2017
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28874586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24375224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617244
|full-text-url=https://sci-hub.do/10.1093/ageing/aft206
}}
}}
* {{medline-title
* {{medline-title
|title=Hippocampal sclerosis, hippocampal neuron loss patterns and TDP-43 in the aged population.
|title=Physiological response to a breed evaluation field test in Icelandic horses.
|date=07.2018
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28833898
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24387835
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099461
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942816
}}
}}
==SIRT1==
* {{medline-title
* {{medline-title
|title=Distribution of corticotropin-releasing factor receptor 1 in the developing mouse forebrain: A novel sex difference revealed in the rostral periventricular hypothalamus.
|title=Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats.
|date=11.10.2017
|date=03.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28823817
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173945
|full-text-url=https://sci-hub.do/10.1111/acel.13279
}}
}}
* {{medline-title
* {{medline-title
|title=Clinical-grade human umbilical cord-derived mesenchymal stem cells reverse cognitive aging via improving synaptic plasticity and endogenous neurogenesis.
|title=Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective.
|date=10.08.2017
|date=05.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28796260
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33280374
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596535
|full-text-url=https://sci-hub.do/10.1021/acschemneuro.0c00696
}}
}}
* {{medline-title
|title=Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33149857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585532
}}
* {{medline-title
|title=[[SIRT1]] Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence.
|date=04.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33158256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694272
}}
* {{medline-title
|title=Histone Deacetylase [[SIRT1]], Smooth Muscle Cell Function, and Vascular Diseases.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573826
}}
* {{medline-title
|title=6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing [[SIRT1]] and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation.
|date=27.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33111210
|full-text-url=https://sci-hub.do/10.1007/s11010-020-03951-z
}}
* {{medline-title
|title=Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through [[SIRT1]] activation and AKT/mTOR pathway inhibition.
|date=30.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010892
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.09.096
}}
* {{medline-title
|title=[[SIRT1]] Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508177
}}
* {{medline-title
|title=The Role of Sirtuins in Kidney Diseases.
|date=12.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555196
}}
* {{medline-title
|title=The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men.
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32919015
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111090
}}
* {{medline-title
|title=Virus-Induced Asthma Exacerbations: [[SIRT1]] Targeted Approach.
|date=13.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32823491
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464235
}}
* {{medline-title
|title=Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793997
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09896-6
}}
* {{medline-title
|title=Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/[[SIRT1]]-FOXA3-Beclin1 pathway.
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768436
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111053
}}
* {{medline-title
|title=Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32722945
|full-text-url=https://sci-hub.do/10.1080/15412555.2020.1797657
}}
* {{medline-title
|title=Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of [[SIRT1]] in Human Dermal Fibroblasts.
|date=01.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32404543
|full-text-url=https://sci-hub.do/10.1248/bpb.b20-00094
}}
* {{medline-title
|title=SRT1720-induced activation of [[SIRT1]] alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485.
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32421926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327920
}}
* {{medline-title
|title=miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32292498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150474
}}
* {{medline-title
|title=Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes.
|date=01-12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153179
}}
* {{medline-title
|title=Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32249404
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09875-x
}}
* {{medline-title
|title=The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32214805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084123
}}
* {{medline-title
|title=Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158519
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048230
}}
* {{medline-title
|title=Spatiotemporal gating of [[SIRT1]] functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia.
|date=24.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32152092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104039
}}
* {{medline-title
|title=Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of [[SIRT1]].
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32132865
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053352
}}
* {{medline-title
|title=[[SIRT1]] and aging related signaling pathways.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32084459
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111215
}}
* {{medline-title
|title=Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of [[SIRT1]] signaling.
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32088214
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117452
}}
* {{medline-title
|title=Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of [[SIRT1]] activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206476
}}
* {{medline-title
|title=Deacetylation of MRTF-A by [[SIRT1]] defies senescence induced down-regulation of collagen type I in fibroblast cells.
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061777
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165723
}}
* {{medline-title
|title=Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal [[SIRT1]] Levels Improving Cognition in Aged Rats.
|date=26.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31991916
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071257
}}
* {{medline-title
|title=Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating [[SIRT1]].
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957441
}}
* {{medline-title
|title=Two novel [[SIRT1]] activators, SCIC2 and SCIC2.1, enhance [[SIRT1]]-mediated effects in stress response and senescence.
|date=06-07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31942817
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574383
}}
* {{medline-title
|title=Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
|date=23.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31881011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949053
}}
* {{medline-title
|title=The protective role of omentin-1 in IL-1β-induced chondrocyte senescence.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31852248
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1699803
}}
* {{medline-title
|title=The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD  Level Is Lower than the Sirtuin-Saturating Concentrations.
|date=24.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31878234
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982340
}}
* {{medline-title
|title=Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells.
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214571
}}
* {{medline-title
|title=Central nervous system [[SIRT1]] expression is required for cued and contextual fear conditioning memory responses in aging mice.
|date=23.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31763496
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839599
}}
* {{medline-title
|title=Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31785216
}}
* {{medline-title
|title=CO ameliorates endothelial senescence induced by 5-fluorouracil through [[SIRT1]] activation.
|date=30.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704100
|full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108185
}}
* {{medline-title
|title=Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating [[SIRT1]] expression.
|date=20.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31631065
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398
}}
* {{medline-title
|title=The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31572218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751260
}}
* {{medline-title
|title=Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544977
|full-text-url=https://sci-hub.do/10.1002/jcp.29182
}}
* {{medline-title
|title=Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure.
|date=13.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552414
|full-text-url=https://sci-hub.do/10.1093/sleep/zsz217
}}
* {{medline-title
|title=Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of [[SIRT1]].
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710442
}}
* {{medline-title
|title=Activation of the miR-34a-Mediated [[SIRT1]]/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31420820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985387
}}
* {{medline-title
|title=[Ginsenoside Rg_1 induces leukemia stem cell senescence via [[SIRT1]]/TSC_2 signal axis].
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31359662
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20190218.002
}}
* {{medline-title
|title=miR-23b-3p regulates apoptosis and autophagy via suppressing [[SIRT1]] in lens epithelial cells.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31338869
|full-text-url=https://sci-hub.do/10.1002/jcb.29270
}}
* {{medline-title
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3
}}
* {{medline-title
|title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565
|full-text-url=https://sci-hub.do/10.1089/cell.2019.0010
}}
* {{medline-title
|title=Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence.
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31265875
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159039
}}
* {{medline-title
|title=Involvement of [i]microRNA-34a[/i] in Age-Related Susceptibility to Oxidative Stress in ARPE-19 Cells by Targeting the Silent Mating Type Information Regulation 2 Homolog 1/p66shc Pathway: Implications for Age-Related Macular Degeneration.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31249522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584679
}}
* {{medline-title
|title=[[GPR39]] agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237151
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1626405
}}
* {{medline-title
|title=Rational design of novel sirtuin 1 activators via structure-activity insights from application of QSAR modeling.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31217784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558509
}}
* {{medline-title
|title=Metformin prevents murine ovarian aging.
|date=10.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182682
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594816
}}
* {{medline-title
|title=Time-restricted feeding delays the emergence of the age-associated, neoplastic-prone tissue landscape.
|date=12.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594823
}}
* {{medline-title
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|date=10.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
}}
* {{medline-title
|title=[[SIRT1]] protects cochlear hair cell and delays age-related hearing loss via autophagy.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170533
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.04.003
}}
* {{medline-title
|title=Transcriptome analysis revealed potential mechanisms of differences in physiological stress responses between caged male and female magpies.
|date=03.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31159743
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547487
}}
* {{medline-title
|title=Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31144244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885080
}}
* {{medline-title
|title=Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31132911
|full-text-url=https://sci-hub.do/10.1080/10799893.2019.1605529
}}
* {{medline-title
|title=Molecular and Cellular Characterization of [[SIRT1]] Allosteric Activators.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31087296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567996
}}
* {{medline-title
|title=Total flavonoids from the Carya cathayensis Sarg. leaves inhibit HUVEC senescence through the miR-34a/[[SIRT1]] pathway.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31106472
|full-text-url=https://sci-hub.do/10.1002/jcb.28986
}}
* {{medline-title
|title=Impaired [[SIRT1]] activity leads to diminution in glomerular endowment without accelerating age-associated GFR decline.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31087539
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513772
}}
* {{medline-title
|title=Estrogen-[[SIRT1]] Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis.
|date=01.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31105126
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976724
}}
* {{medline-title
|title=Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075496
|full-text-url=https://sci-hub.do/10.1016/j.gep.2019.05.001
}}
* {{medline-title
|title=Protective effect of vildagliptin on [[TNF]]-α-induced chondrocyte senescence.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026379
|full-text-url=https://sci-hub.do/10.1002/iub.2049
}}
* {{medline-title
|title=Polymorphism rs7895833 in the [[SIRT1]] gene and its association with dyslipidaemia in the elderly.
|date=07-08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31040057
|full-text-url=https://sci-hub.do/10.1016/j.regg.2019.01.008
}}
* {{medline-title
|title=Modulation of miR-34a/[[SIRT1]] signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026620
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.03.013
}}
* {{medline-title
|title=Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the [[SIRT1]] pathway in aged bone marrow.
|date=18.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31000692
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472410
}}
* {{medline-title
|title=Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom [i]Cordyceps militaris[/i] Linn., Ameliorates Age-Related Testicular Dysfunction in Rats.
|date=23.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31018574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520895
}}
* {{medline-title
|title=The resistant effect of [[SIRT1]] in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway.
|date=31.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30967498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509061
}}
* {{medline-title
|title=Photobiomodulation and Coenzyme Q  Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313
}}
* {{medline-title
|title=The role of [[SIRT1]] in neuroinflammation and cognitive dysfunction in aged rats after anesthesia and surgery.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30972182
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456566
}}
* {{medline-title
|title=NAD  supplementation rejuvenates aged gut adult stem cells.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30917412
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516145
}}
* {{medline-title
|title=[[NMNAT2]]-mediated NAD  generation is essential for quality control of aged oocytes.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909324
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161
}}
* {{medline-title
|title=Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30889315
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566063
}}
* {{medline-title
|title=Drugs targeting [[SIRT1]], a new generation of therapeutics for osteoporosis and other bone related disorders?
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862606
|full-text-url=https://sci-hub.do/10.1016/j.phrs.2019.03.007
}}
* {{medline-title
|title=Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks.
|date=11.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862067
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429360
}}
* {{medline-title
|title=Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30794349
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413655
}}
* {{medline-title
|title=Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson's disease.
|date=04.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30718471
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362163
}}
* {{medline-title
|title=Bone Marrow Mesenchymal Stem Cells-Derived Exosomal MiR-29b-3p Regulates Aging-Associated Insulin Resistance.
|date=26.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30715852
|full-text-url=https://sci-hub.do/10.1021/acsnano.8b09375
}}
* {{medline-title
|title=Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712161
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00663-x
}}
* {{medline-title
|title=Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684534
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.020
}}
* {{medline-title
|title=Generation of a novel model of primary human cell senescence through Tenovin-6 mediated inhibition of sirtuins.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666570
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535423
}}
* {{medline-title
|title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016
}}
* {{medline-title
|title=Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism.
|date=23.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673631
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366955
}}
* {{medline-title
|title=Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622668
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304815
}}
* {{medline-title
|title=NKT-like cells reveal higher than T lymphocytes expression of cellular protective proteins HSP70 and [[SOD2]] and comparably increased expression of [[SIRT1]] in the oldest seniors.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30633320
|full-text-url=https://sci-hub.do/10.5603/FHC.a2018.0025
}}
* {{medline-title
|title=Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30597622
|full-text-url=https://sci-hub.do/10.1111/jpi.12550
}}
* {{medline-title
|title=Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats.
|date=23.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30582744
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326662
}}
* {{medline-title
|title=Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30537739
|full-text-url=https://sci-hub.do/10.1159/000495895
}}
* {{medline-title
|title=Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530184
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.11.139
}}
* {{medline-title
|title=CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins [[SIRT1]], HSP70 and [[SOD2]].
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534181
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262966
}}
* {{medline-title
|title=Amentoflavone Induces Autophagy and Modulates p53.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30507085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275431
}}
* {{medline-title
|title=Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30476532
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.017
}}
* {{medline-title
|title=Sirtuins: Developing Innovative Treatments for Aged-Related Memory Loss and Alzheimer's Disease.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30484407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538488
}}
* {{medline-title
|title=N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30447351
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.11.006
}}
* {{medline-title
|title=Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice.
|date=20.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296764
}}
* {{medline-title
|title=Metformin Is a Direct [[SIRT1]]-Activating Compound: Computational Modeling and Experimental Validation.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30459716
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232372
}}
* {{medline-title
|title=Hsp90 Stabilizes [[SIRT1]] Orthologs in Mammalian Cells and [i]C. elegans[/i].
|date=20.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274930
}}
* {{medline-title
|title=Sirtuins and NAD  in the Development and Treatment of Metabolic and Cardiovascular Diseases.
|date=14.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206880
}}
* {{medline-title
|title=[[SIRT1]] deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30295421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260920
}}
* {{medline-title
|title=Prevention of Senescence in Vasculature Through Quiescence.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30259779
|full-text-url=https://sci-hub.do/10.1089/rej.2018.2138
}}
* {{medline-title
|title=Melatonin and inflammation-Story of a double-edged blade.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884
|full-text-url=https://sci-hub.do/10.1111/jpi.12525
}}
* {{medline-title
|title=[[ALDH2]] mediates the dose-response protection of chronic ethanol against endothelial senescence through [[SIRT1]]/p53 pathway.
|date=12.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217444
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.081
}}
* {{medline-title
|title=Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30196020
|full-text-url=https://sci-hub.do/10.1016/j.jphs.2018.08.006
}}
* {{medline-title
|title=Endothelial [[SIRT1]] prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells.
|date=01.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165439
|full-text-url=https://sci-hub.do/10.1093/cvr/cvy212
}}
* {{medline-title
|title=Effects of Ginsenoside Rg3 on fatigue resistance and [[SIRT1]] in aged rats.
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30144466
|full-text-url=https://sci-hub.do/10.1016/j.tox.2018.08.010
}}
* {{medline-title
|title=[[PARP1]] inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD  levels and increasing [[SIRT1]] activity.
|date=23.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30139380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107962
}}
* {{medline-title
|title=Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing [[SIRT1]] and [[SIRT3]] expression.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30132522
|full-text-url=https://sci-hub.do/10.3892/mmr.2018.9390
}}
* {{medline-title
|title=Liver regeneration in aged mice: new insights.
|date=28.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30157472
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128415
}}
* {{medline-title
|title=Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit's Heart and Liver.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079382
}}
* {{medline-title
|title=Defect of [[SIRT1]]-FoxO3a axis is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated cellular senescence and nematode aging.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30103847
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507845
}}
* {{medline-title
|title=Master athletes have higher miR-7, [[SIRT3]] and [[SOD2]] expression in skeletal muscle than age-matched sedentary controls.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30107294
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092475
}}
* {{medline-title
|title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes.
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186
}}
* {{medline-title
|title=[[PGC]]-1α Protects [[RPE]] Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis.
|date=07.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121367
}}
* {{medline-title
|title=Effect of oral appliance on circulating leukocyte telomere length and [[SIRT1]] in obstructive sleep apnea.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030618
|full-text-url=https://sci-hub.do/10.1007/s00784-018-2560-5
}}
* {{medline-title
|title=miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating [[SIRT1]] (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase).
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30026277
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.311298
}}
* {{medline-title
|title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862
}}
* {{medline-title
|title=Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/[[SIRT1]] signaling pathway.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040122
}}
* {{medline-title
|title=Sirtuin 1 and Alzheimer's disease: An up-to-date review.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30007474
|full-text-url=https://sci-hub.do/10.1016/j.npep.2018.07.001
}}
* {{medline-title
|title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500
}}
* {{medline-title
|title=Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-[[SIRT1]]-eNOS pathway.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29992759
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6111868
}}
* {{medline-title
|title=Serum containing Buyang Huanwu decoction prevents age-associated migration and invasion of human vascular smooth muscle cells by up regulating [[SIRT1]] expression.
|date=17.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952352
|full-text-url=https://sci-hub.do/10.5582/bst.2018.01063
}}
* {{medline-title
|title=Role of accelerated aging in limb muscle wasting of patients with COPD.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970961
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022820
}}
* {{medline-title
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells.
|date=15.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031
}}
* {{medline-title
|title=Mesenchymal stem cells confer resistance to doxorubicin-induced cardiac senescence by inhibiting microRNA-34a.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29928373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004710
}}
* {{medline-title
|title=The circadian clock in adult neural stem cell maintenance.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29886147
|full-text-url=https://sci-hub.do/10.1016/j.pneurobio.2018.05.007
}}
* {{medline-title
|title=Resveratrol reduces senescence-associated secretory phenotype by [[SIRT1]]/NF-κB pathway in gut of the annual fish Nothobranchius guentheri.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29908321
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.06.027
}}
* {{medline-title
|title=Loss of [[NAMPT]] in aging retinal pigment epithelium reduces NAD  availability and promotes cellular senescence.
|date=12.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046249
}}
* {{medline-title
|title=Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860669
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021292
}}
* {{medline-title
|title=[[SIRT1]], miR-132 and miR-212 link human longevity to Alzheimer's Disease.
|date=31.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29855513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981646
}}
* {{medline-title
|title=Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29851177
|full-text-url=https://sci-hub.do/10.1002/cbin.10999
}}
* {{medline-title
|title=Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial Function.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797808
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973912
}}
* {{medline-title
|title=Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/[[SIRT1]]/[[PGC]]-1a Pathway in Skeletal Muscle from Naturally Aging Rats.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29806860
|full-text-url=https://sci-hub.do/10.1007/s12603-018-1015-7
}}
* {{medline-title
|title=[[SIRT1]] reverses senescence via enhancing autophagy and attenuates oxidative stress-induced apoptosis through promoting p53 degradation.
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29803744
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.05.174
}}
* {{medline-title
|title=Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774638
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052398
}}
* {{medline-title
|title=Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29753753
|full-text-url=https://sci-hub.do/10.1016/j.neubiorev.2018.05.011
}}
* {{medline-title
|title=Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of [[SIRT1]].
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29725214
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932937
}}
* {{medline-title
|title=Role of hypothalamus in aging and its underlying cellular mechanisms.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29729230
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.04.008
}}
* {{medline-title
|title=The variable role of [[SIRT1]] in the maintenance and differentiation of mesenchymal stem cells.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29715067
|full-text-url=https://sci-hub.do/10.2217/rme-2017-0128
}}
* {{medline-title
|title=Sirtuins in Renal Health and Disease.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712732
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050939
}}
* {{medline-title
|title=Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, [[SIRT1]], [[SIRT3]], and VEGF in the Substantia Nigra.
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659739
|full-text-url=https://sci-hub.do/10.1093/gerona/gly072
}}
* {{medline-title
|title=MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells.
|date=03.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615114
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883541
}}
* {{medline-title
|title=Natural products with anti-aging potential: Affected targets and molecular mechanisms.
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29597027
|full-text-url=https://sci-hub.do/10.1016/j.biotechadv.2018.03.012
}}
* {{medline-title
|title=[Effect of microRNA-34a/[[SIRT1]]/p53 signal pathway on notoginsenoside R₁ delaying vascular endothelial cell senescence].
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29600625
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180110.001
}}
* {{medline-title
|title=[[SIRT1]] and microRNAs: The role in breast, lung and prostate cancers.
|date=01.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29574020
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.03.023
}}
* {{medline-title
|title=Leukotriene D4 induces cellular senescence in osteoblasts.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587204
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2017.12.027
}}
* {{medline-title
|title=Impairment of an Endothelial NAD -H S Signaling Network Is a Reversible Cause of Vascular Aging.
|date=22.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884172
}}
* {{medline-title
|title=Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564694
|full-text-url=https://sci-hub.do/10.1007/s11102-018-0881-7
}}
* {{medline-title
|title=Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.
|date=06.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29514072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854409
}}
* {{medline-title
|title=Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476819
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.004
}}
* {{medline-title
|title=[[HGF]] and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the [[SIRT1]]/[[FOXO1]] Signaling Pathway.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462806
|full-text-url=https://sci-hub.do/10.1159/000487559
}}
* {{medline-title
|title=The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407880
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2018.01.043
}}
* {{medline-title
|title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018
}}
* {{medline-title
|title=Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29331588
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2017.12.021
}}
* {{medline-title
|title=Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress.
|date=20.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325896
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.01.007
}}
* {{medline-title
|title=Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury.
|date=11.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811244
}}
* {{medline-title
|title=Acetylshikonin from Zicao attenuates cognitive impairment and hippocampus senescence in d-galactose-induced aging mouse model via upregulating the expression of [[SIRT1]].
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325995
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2018.01.007
}}
* {{medline-title
|title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812
|full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0
}}
* {{medline-title
|title=Sirtuins in Brain Aging and Neurological Disorders.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29283326
|full-text-url=https://sci-hub.do/10.1615/CritRevEukaryotGeneExpr.2017019532
}}
* {{medline-title
|title=[Aging-related change of erectile function and the expression of [[SIRT1]]].
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29282911
}}
* {{medline-title
|title=Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715387
}}
* {{medline-title
|title=Maternal aging affects oocyte resilience to carbonyl cyanide-m-chlorophenylhydrazone -induced mitochondrial dysfunction in cows.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182624
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705080
}}
* {{medline-title
|title=Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating [[SIRT1]] activity and antioxidant gene expression in mouse cells.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29178516
|full-text-url=https://sci-hub.do/10.1111/gtc.12542
}}
* {{medline-title
|title=Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™).
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177909
|full-text-url=https://sci-hub.do/10.1007/s12015-017-9784-7
}}
* {{medline-title
|title=Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through [[SIRT1]].
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29118911
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666058
}}
* {{medline-title
|title=Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating [[SIRT1]]-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation.
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707715
}}
* {{medline-title
|title=Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice.
|date=13.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29137352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663524
}}
* {{medline-title
|title=O-GlcNAcylation of [[SIRT1]] enhances its deacetylase activity and promotes cytoprotection under stress.
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29133780
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684413
}}
* {{medline-title
|title=Aging as an Epigenetic Phenomenon.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635645
}}
* {{medline-title
|title=MeCP2 mediated dysfunction in senescent EPCs.
|date=03.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29108229
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667962
}}
* {{medline-title
|title=Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063982
|full-text-url=https://sci-hub.do/10.1007/s10571-017-0557-2
}}
* {{medline-title
|title=A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction.
|date=12.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29029466
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630366
}}
* {{medline-title
|title=Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence.
|date=17.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29041897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645932
}}
* {{medline-title
|title=Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts.
|date=28.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28964787
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2017.09.027
}}
* {{medline-title
|title=Blocking [[SIRT1]] inhibits cell proliferation and promotes aging through the PI3K/AKT pathway.
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28962864
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.09.037
}}
* {{medline-title
|title=[[SIRT1]] is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28937996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609767
}}
* {{medline-title
|title=[Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell].
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952264
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.2017.0012
}}
* {{medline-title
|title=[[SIRT1]] is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity.
|date=05.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28923345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756502
}}
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
* {{medline-title
|title=The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847722
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.032
}}
* {{medline-title
|title=Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808887
|full-text-url=https://sci-hub.do/10.1007/s11481-017-9759-0
}}
* {{medline-title
|title=Aquatide Activation of [[SIRT1]] Reduces Cellular Senescence through a [[SIRT1]]-[[FOXO1]]-Autophagy Axis.
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822991
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590795
}}
* {{medline-title
|title=Obesity and aging diminish sirtuin 1 ([[SIRT1]])-mediated deacetylation of [[SIRT3]], leading to hyperacetylation and decreased activity and stability of [[SIRT3]].
|date=20.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655509
}}
* {{medline-title
|title=Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging.
|date=10.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28802039
|full-text-url=https://sci-hub.do/10.1016/j.cell.2017.07.042
}}
* {{medline-title
|title=High glucose and free fatty acids induce endothelial progenitor cell senescence via [[PGC]]-1α/[[SIRT1]] signaling pathway.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28786152
|full-text-url=https://sci-hub.do/10.1002/cbin.10833
}}
* {{medline-title
|title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417
}}
* {{medline-title
|title=Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28770437
|full-text-url=https://sci-hub.do/10.1007/s11064-017-2369-7
}}
* {{medline-title
|title=Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28744338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506461
}}
* {{medline-title
|title=Inflammation, Stem Cells, and the Aging Hypothalamus.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28756738
|full-text-url=https://sci-hub.do/10.1089/rej.2017.2002
}}
* {{medline-title
|title=Myricetin improves endurance capacity and mitochondrial density by activating [[SIRT1]] and [[PGC]]-1α.
|date=24.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28740165
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524912
}}
* {{medline-title
|title=Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and [[SIRT1]] in Degenerative Disease and Cancer.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28721811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600856
}}
* {{medline-title
|title=The emerging role of alternative splicing in senescence and aging.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28703423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595669
}}
* {{medline-title
|title=miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28699360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544174
}}
* {{medline-title
|title=Regulation of [[SIRT1]]/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676953
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2021-y
}}
* {{medline-title
|title=[[SIRT1]] and [[SIRT6]] Signaling Pathways in Cardiovascular Disease Protection.
|date=10.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28661724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824538
}}
* {{medline-title
|title=Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging.
|date=30.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883375
}}
* {{medline-title
|title=Reduction in podocyte [[SIRT1]] accelerates kidney injury in aging mice.
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28615249
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625108
}}
* {{medline-title
|title=Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs.
|date=12.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28611316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509453
}}
* {{medline-title
|title=Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28558631
|full-text-url=https://sci-hub.do/10.2174/1874609810666170531103140
}}
* {{medline-title
|title=The NAD /[[PARP1]]/[[SIRT1]] Axis in Aging.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28537485
|full-text-url=https://sci-hub.do/10.1089/rej.2017.1980
}}
* {{medline-title
|title=Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28552621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581719
}}
* {{medline-title
|title=Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-[[SIRT1]] pathway.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28544111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506400
}}
* {{medline-title
|title=Bushen-Yizhi formula ameliorates cognitive dysfunction through [[SIRT1]]/ER stress pathway in SAMP8 mice.
|date=25.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28521305
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564772
}}
* {{medline-title
|title=Caveolin-1 deficiency induces premature senescence with mitochondrial dysfunction.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28514055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506423
}}
* {{medline-title
|title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465
}}
* {{medline-title
|title=Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28488286
|full-text-url=https://sci-hub.do/10.1111/and.12816
}}
* {{medline-title
|title=Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28477081
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9705-9
}}
* {{medline-title
|title=Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment.
|date=30.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28415598
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482635
}}
* {{medline-title
|title=During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412652
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397018
}}
* {{medline-title
|title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts.
|date=01.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944
}}
* {{medline-title
|title=Regulation of stem cell aging by [[SIRT1]] - Linking metabolic signaling to epigenetic modifications.
|date=05.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28392411
|full-text-url=https://sci-hub.do/10.1016/j.mce.2017.03.031
}}
* {{medline-title
|title=Ampelopsin attenuates the atrophy of skeletal muscle from d-gal-induced aging rats through activating AMPK/[[SIRT1]]/PGC-1α signaling cascade.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28364603
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2017.03.070
}}
* {{medline-title
|title=[[SIRT1]] Polymorphisms and Serum-Induced [[SIRT1]] Protein Expression in Aging and Frailty: The CHAMP Study.
|date=01.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28329314
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279142
}}
* {{medline-title
|title=Melatonin reverses H  O  -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28295567
|full-text-url=https://sci-hub.do/10.1111/jpi.12407
}}
* {{medline-title
|title=Alkylresorcinols activate [[SIRT1]] and delay ageing in Drosophila melanogaster.
|date=02.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28252007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333101
}}
* {{medline-title
|title=Tat-Mediated Induction of miRs-34a

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  • Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of D-galactose treated mice. / 02.2015 / PubMed / Full text
  • Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice. / 05.01.2015 / PubMed / Full text
  • Tumor necrosis factor-α-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo. / 01.2015 / PubMed / Full text
  • Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice. / 15.01.2015 / PubMed / Full text
  • Pre-Operative, High-IL-6 Blood Level is a Risk Factor of Post-Operative Delirium Onset in Old Patients. / 2014 / PubMed / Full text
  • Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease. / 2015 / PubMed / Full text
  • Inflammasomes in neuroinflammation and changes in brain function: a focused review. / 2014 / PubMed / Full text
  • Impact of gasless laparoscopy on circulation, respiration, stress response, and other complications in gynecological geriatrics. / 2014 / PubMed / Full text
  • Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice. / 17.11.2014 / PubMed / Full text
  • Sleep deprivation and divergent toll-like receptor-4 activation of cellular inflammation in aging. / 01.02.2015 / PubMed / Full text
  • Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging. / 11.2015 / PubMed / Full text
  • The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice. / 15.12.2014 / PubMed / Full text
  • Evidence for altered inflammatory and repair responses in symptomatic carotid plaques from elderly patients. / 11.2014 / PubMed / Full text
  • Immunosenescence in monocytes, macrophages, and dendritic cells: lessons learned from the lung and heart. / 11.2014 / PubMed / Full text
  • Ferrocifen derivatives that induce senescence in cancer cells: selected examples. / 12.2014 / PubMed / Full text
  • Role of mitochondrial reactive oxygen species in age-related inflammatory activation of endothelium. / 08.2014 / PubMed / Full text
  • Aging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery. / 2014 / PubMed / Full text
  • Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson's disease by laser ablation inductively coupled plasma mass spectrometry. / 20.08.2014 / PubMed / Full text
  • Interleukin-1 deficiency prolongs ovarian lifespan in mice. / 26.08.2014 / PubMed / Full text
  • HIV-1 transgenic rats display alterations in immunophenotype and cellular responses associated with aging. / 2014 / PubMed / Full text
  • Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers. / 01.2015 / PubMed / Full text
  • Relationship between vitamin D and inflammatory markers in older individuals. / 2014 / PubMed / Full text
  • Association of pulse pressure with serum TNF-α and neutrophil count in the elderly. / 2014 / PubMed / Full text
  • Peritoneal exudate cells from long-lived rats exhibit increased IL-10/IL-1β expression ratio and preserved NO/urea ratio following LPS-stimulation in vitro. / 2014 / PubMed / Full text
  • Cortisol, cytokines, and hippocampal volume interactions in the elderly. / 2014 / PubMed / Full text
  • DaoTan decoction (DTD) inhibits tumor necrosis factor-α (TNF-α)-induced expression of intercellular adhesion molecule-1 (ICAM-1), p53 and p21, in human umbilical vein endothelia cells (HUVECs). / 10.2014 / PubMed / Full text
  • Improvement in Th1/Th2 immune homeostasis, antioxidative status and resistance to pathogenic E. coli on consumption of probiotic Lactobacillus rhamnosus fermented milk in aging mice. / 2014 / PubMed / Full text
  • Aging oppositely affects TNF-α and IL-10 production by macrophages from different rat strains. / 2014 / PubMed / Full text
  • Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging. / 2014 / PubMed / Full text
  • iPLA2β knockout mouse, a genetic model for progressive human motor disorders, develops age-related neuropathology. / 08.2014 / PubMed / Full text
  • Site-specific changes in cytokine response to septic dose of lipopolysaccharide in ovariectomized female rats. / 08.2014 / PubMed / Full text
  • D-galactose induced inflammation lipid peroxidation and platelet activation in rats. / 09.2014 / PubMed / Full text
  • Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity. / 05.2014 / PubMed / Full text
  • Bacteria and Toll-like receptor and cytokine mRNA expression profiles associated with canine arthritis. / 15.08.2014 / PubMed / Full text
  • Distinct age-matched serum biomarker profiles in patients with cutaneous T-cell lymphoma. / 08.2014 / PubMed / Full text
  • Age-related activation of MKK/p38/NF-κB signaling pathway in lung: from mouse to human. / 09.2014 / PubMed / Full text
  • Changes in the expression of the Toll-like receptor system in the aging rat kidneys. / 2014 / PubMed / Full text
  • Comparative analysis of low-level laser therapy (660 nm) on inflammatory biomarker expression during the skin wound-repair process in young and aged rats. / 09.2014 / PubMed / Full text
  • Inflammation and prolonged QT time: results from the Cardiovascular Disease, Living and Ageing in Halle (CARLA) study. / 2014 / PubMed / Full text
  • Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state. / 11.2014 / PubMed / Full text
  • Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals. / 08.2014 / PubMed / Full text
  • Maturation of innate responses to mycobacteria over the first nine months of life. / 15.05.2014 / PubMed / Full text
  • Effects of age and macrophage lineage on intracellular survival and cytokine induction after infection with Rhodococcus equi. / 15.07.2014 / PubMed / Full text
  • IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice. / 06.2014 / PubMed / Full text
  • A comparison of pro-inflammatory cytokine mRNA expression in equine bronchoalveolar lavage (BAL) and peripheral blood. / 15.04.2014 / PubMed / Full text
  • Moderate swimming exercise and caffeine supplementation reduce the levels of inflammatory cytokines without causing oxidative stress in tissues of middle-aged rats. / 05.2014 / PubMed / Full text
  • Effects of aging on influenza virus infection dynamics. / 04.2014 / PubMed / Full text
  • Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for "inflamm-aging". / 05.2014 / PubMed / Full text
  • Markers of low-grade inflammation and endothelial dysfunction are related to reduced information processing speed and executive functioning in an older population - the Hoorn Study. / 02.2014 / PubMed / Full text
  • Bacopa monnieri (L.) exerts anti-inflammatory effects on cells of the innate immune system in vitro. / 03.2014 / PubMed / Full text
  • Resveratrol increases antioxidant defenses and decreases proinflammatory cytokines in hippocampal astrocyte cultures from newborn, adult and aged Wistar rats. / 06.2014 / PubMed / Full text
  • High TNF-α levels in resting B cells negatively correlate with their response. / 06.2014 / PubMed / Full text
  • Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life. / 06.2014 / PubMed / Full text

APOE[править]

  • Polygenic risk score of longevity predicts longer survival across an age-continuum. / 20.11.2020 / PubMed / Full text
  • Association Between APOE Alleles and Change of Neuropsychological Tests in the Long Life Family Study. / 17.11.2020 / PubMed / Full text
  • The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans. / 20.11.2020 / PubMed / Full text
  • Homozygosity in the [i]APOE[/i] 3 Polymorphism Is Associated With Less Depression and Higher Serum Low-Density Lipoprotein in Chinese Elderly Schizophrenics. / 2020 / PubMed / Full text
  • Effect of apolipoprotein E polymorphism on cognition and brain in the Cambridge Centre for Ageing and Neuroscience cohort. / 01-12.2020 / PubMed / Full text
  • Cardiovascular risk factors and APOE-ε4 status affect memory functioning in aging via changes to temporal stem diffusion. / 18.10.2020 / PubMed / Full text
  • APOE [i]ε[/i]4 and resting-state functional connectivity in racially/ethnically diverse older adults. / 2020 / PubMed / Full text
  • Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study. / 13.11.2020 / PubMed / Full text
  • When Culture Influences Genes: Positive Age Beliefs Amplify the Cognitive-Aging Benefit of APOE ε2. / 14.09.2020 / PubMed / Full text
  • Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study. / 08.2020 / PubMed / Full text
  • Estimating the potential for dementia prevention through modifiable risk factors elimination in the real-world setting: a population-based study. / 07.08.2020 / PubMed / Full text
  • Machine learning-based estimation of cognitive performance using regional brain MRI markers: the Northern Manhattan Study. / 01.08.2020 / PubMed / Full text
  • Effects of an APOE Promoter Polymorphism on Fronto-Parietal Functional Connectivity During Nondemented Aging. / 2020 / PubMed / Full text
  • The relationship of parental longevity with the aging brain-results from UK Biobank. / 10.2020 / PubMed / Full text
  • Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation. / 30.06.2020 / PubMed / Full text
  • Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease. / 2020 / PubMed / Full text
  • Effects of sex, age, and apolipoprotein E genotype on hippocampal parenchymal fraction in cognitively normal older adults. / 30.07.2020 / PubMed / Full text
  • Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO). / 05.05.2020 / PubMed / Full text
  • Apolipoprotein E and Health in Older Men: The Concord Health and Ageing in Men Project. / 25.09.2020 / PubMed / Full text
  • CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease. / 07.2020 / PubMed / Full text
  • Association of Cardiovascular Risk Factors with Cerebral Perfusion in Whites and African Americans. / 2020 / PubMed / Full text
  • Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways. / 03.06.2020 / PubMed / Full text
  • Less agreeable, better preserved? A PET amyloid and MRI study in a community-based cohort. / 05.2020 / PubMed / Full text
  • Physical Activity as Moderator of the Association Between APOE and Cognitive Decline in Older Adults: Results from Three Longitudinal Cohort Studies. / 25.09.2020 / PubMed / Full text
  • Longitudinal Maintenance of Cognitive Health in Centenarians in the 100-plus Study. / 05.02.2020 / PubMed / Full text
  • Interaction of APOE, cerebral blood flow, and cortical thickness in the entorhinal cortex predicts memory decline. / 04.2020 / PubMed / Full text
  • Determinants of mesial temporal lobe volume loss in older individuals with preserved cognition: a longitudinal PET amyloid study. / 03.2020 / PubMed / Full text
  • Long-term exposure to ambient air pollution, APOE-ε4 status, and cognitive decline in a cohort of older adults in northern Manhattan. / 03.2020 / PubMed / Full text
  • Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice. / 2020 / PubMed / Full text
  • APOE region molecular signatures of Alzheimer's disease across races/ethnicities. / 03.2020 / PubMed / Full text
  • Varying Effects of APOE Alleles on Extreme Longevity in European Ethnicities. / 13.11.2019 / PubMed / Full text
  • Prospective Evaluation of Cognitive Health and Related Factors in Elderly at Risk for Developing Alzheimer's Dementia: A Longitudinal Cohort Study. / 2019 / PubMed / Full text
  • Association of Cardiovascular and Alzheimer's Disease Risk Factors with Intracranial Arterial Blood Flow in Whites and African Americans. / 2019 / PubMed / Full text
  • Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease? / 17.04.2020 / PubMed / Full text
  • Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study. / 02.2020 / PubMed / Full text
  • Prospective Memory: Age related change is influenced by APOE genotype. / 09.2020 / PubMed / Full text
  • Education Moderates the Relation Between APOE ɛ4 and Memory in Nondemented Non-Hispanic Black Older Adults. / 2019 / PubMed / Full text
  • Apolipoprotein E ε4 allele effects on longitudinal cognitive trajectories are sex and age dependent. / 12.2019 / PubMed / Full text
  • Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects. / 2019 / PubMed / Full text
  • APOE modifies the interaction of entorhinal cerebral blood flow and cortical thickness on memory function in cognitively normal older adults. / 15.11.2019 / PubMed / Full text
  • When time's arrow doesn't bend: APOE-ε4 influences episodic memory before old age. / 10.2019 / PubMed / Full text
  • Cognitive-Motor Integration Performance Is Affected by Sex, APOE Status, and Family History of Dementia. / 2019 / PubMed / Full text
  • Associations among amyloid status, age, and longitudinal regional brain atrophy in cognitively unimpaired older adults. / 10.2019 / PubMed / Full text
  • Cognitive function and neuropathological outcomes: a forward-looking approach. / 12.2019 / PubMed / Full text
  • APOE gene-dependent BOLD responses to a breath-hold across the adult lifespan. / 2019 / PubMed / Full text
  • Medial temporal lobe atrophy and posterior atrophy scales normative values. / 2019 / PubMed / Full text
  • Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study. / 09.2019 / PubMed / Full text
  • Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
  • Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. / 08.2019 / PubMed / Full text
  • Late life insulin resistance and Alzheimer's disease and dementia: The Kuakini Honolulu heart program. / 15.08.2019 / PubMed / Full text
  • Latent Classes of Cognitive Functioning Among Depressed Older Adults Without Dementia. / 09.2019 / PubMed / Full text
  • Lifespan Intellectual Factors, Genetic Susceptibility, and Cognitive Phenotypes in Aging: Implications for Interventions. / 2019 / PubMed / Full text
  • Cyclic O exposure synergizes with aging leading to memory impairment in male APOE ε3, but not APOE ε4, targeted replacement mice. / 09.2019 / PubMed / Full text
  • Alzheimer's disease and symbiotic microbiota: an evolutionary medicine perspective. / 08.2019 / PubMed / Full text
  • The role of APOE in transgenic mouse models of AD. / 10.08.2019 / PubMed / Full text
  • Sex differences in mixed neuropathologies in community-dwelling older adults. / 15.09.2019 / PubMed / Full text
  • Women Outperform Men in Verbal Episodic Memory Even in Oldest-Old Age: 13-Year Longitudinal Results of the AgeCoDe/AgeQualiDe Study. / 2019 / PubMed / Full text
  • APOE Effect on Amyloid-β PET Spatial Distribution, Deposition Rate, and Cut-Points. / 2019 / PubMed / Full text
  • Sex differences in the association of APOE ε4 genotype with longitudinal hippocampal atrophy in cognitively normal older people. / 11.2019 / PubMed / Full text
  • Predictors and Implications of Accelerated Cognitive Aging. / 2018 / PubMed / Full text
  • Association of Cortical β-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease. / 01.07.2019 / PubMed / Full text
  • Sex differences in the association between amyloid and longitudinal brain volume change in cognitively normal older adults. / 2019 / PubMed / Full text
  • Region-specific association between basal blood insulin and cerebral glucose metabolism in older adults. / 2019 / PubMed / Full text
  • Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity. / 10.2020 / PubMed / Full text
  • Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging. / 28.03.2019 / PubMed / Full text
  • Nuances in Alzheimer's Genetic Risk Reveal Differential Predictions of Non-demented Memory Aging Trajectories: Selective Patterns by APOE Genotype and Sex. / 2019 / PubMed / Full text
  • A prospective study of focal brain atrophy, mobility and fitness. / 07.2019 / PubMed / Full text
  • 10-year follow-up of the Super-Seniors Study: compression of morbidity and genetic factors. / 28.02.2019 / PubMed / Full text
  • Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time. / 2019 / PubMed / Full text
  • Taste receptors, innate immunity and longevity: the case of TAS2R16 gene. / 2019 / PubMed / Full text
  • The Role of APOE4 in Disrupting the Homeostatic Functions of Astrocytes and Microglia in Aging and Alzheimer's Disease. / 2019 / PubMed / Full text
  • The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals. / 05.2019 / PubMed / Full text
  • Opposing Roles of apolipoprotein E in aging and neurodegeneration. / 02.2019 / PubMed / Full text
  • Effects of APOE on cognitive aging in community-dwelling older adults. / 03.2019 / PubMed / Full text
  • A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study. / 05.2019 / PubMed / Full text
  • Apolipoprotein E4 Mediates the Association Between Midlife Dyslipidemia and Cerebral Amyloid in Aging Women. / 2019 / PubMed / Full text
  • Apolipoprotein E gene in physiological and pathological aging. / 03.2019 / PubMed / Full text
  • Spatial patterns of white matter hyperintensities associated with Alzheimer's disease risk factors in a cognitively healthy middle-aged cohort. / 24.01.2019 / PubMed / Full text
  • The Role of MRI Biomarkers and Their Interactions with Cognitive Status and APOE ε4 in Nondemented Elderly Subjects. / 2018 / PubMed / Full text
  • Longitudinal tau accumulation and atrophy in aging and alzheimer disease. / 02.2019 / PubMed / Full text
  • Apolipoprotein E Genotypes, Age, Race, and Cognitive Decline in a Population Sample. / 04.2019 / PubMed / Full text
  • Predictors of neurodegeneration differ between cognitively normal and subsequently impaired older adults. / 03.2019 / PubMed / Full text
  • Vascular burden and APOE ε4 are associated with white matter microstructural decline in cognitively normal older adults. / 03.2019 / PubMed / Full text
  • Responses to executive demand in young adulthood differ by APOE genotype. / 15.03.2019 / PubMed / Full text
  • Mild Cognitive Impairment that Does Not Progress to Dementia: A Population-Based Study. / 02.2019 / PubMed / Full text
  • Neuropathologic, genetic, and longitudinal cognitive profiles in primary age-related tauopathy (PART) and Alzheimer's disease. / 01.2019 / PubMed / Full text
  • Independent associations of TOMM40 and APOE variants with body mass index. / 02.2019 / PubMed / Full text
  • Apolipoprotein E genotype moderates the association between dietary polyunsaturated fat and brain function: an exploration of cerebral glutamate and cognitive performance. / 09.2020 / PubMed / Full text
  • Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults. / 09.2018 / PubMed / Full text
  • The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description. / 12.2018 / PubMed / Full text
  • Report: NIA workshop on translating genetic variants associated with longevity into drug targets. / 12.2018 / PubMed / Full text
  • Dendritic spine remodeling accompanies Alzheimer's disease pathology and genetic susceptibility in cognitively normal aging. / 01.2019 / PubMed / Full text
  • The ApoE ε4 Isoform: Can the Risk of Diseases be Reduced by Environmental Factors? / 01.01.2019 / PubMed / Full text
  • Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text
  • Amygdala subnuclei and healthy cognitive aging. / 01.2019 / PubMed / Full text
  • APOE ɛ4, rs405509, and rs440446 promoter and intron-1 polymorphisms and dementia risk in a cohort of elderly Finns-Helsinki Birth Cohort Study. / 01.2019 / PubMed / Full text
  • The Cross-sectional and Longitudinal Associations Between IL-6, IL-10, and TNFα and Cognitive Outcomes in the Mayo Clinic Study of Aging. / 12.07.2019 / PubMed / Full text
  • The effect of midlife cardiovascular risk factors on white matter hyperintensity volume and cognition two decades later in normal ageing women. / 02.2020 / PubMed / Full text
  • Sex and age interact to determine clinicopathologic differences in Alzheimer's disease. / 12.2018 / PubMed / Full text
  • Relationship Between Amyloid-β Positivity and Progression to Mild Cognitive Impairment or Dementia over 8 Years in Cognitively Normal Older Adults. / 2018 / PubMed / Full text
  • Lifetime Risk Factors for Functional and Cognitive Outcomes in Patients with Alzheimer's Disease. / 2018 / PubMed / Full text
  • Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau. / 03.09.2018 / PubMed / Full text
  • Childhood socioeconomic status and genetic risk for poorer cognition in later life. / 09.2018 / PubMed / Full text
  • Diffuse Amyloid-β Plaques, Neurofibrillary Tangles, and the Impact of APOE in Elderly Persons' Brains Lacking Neuritic Amyloid Plaques. / 2018 / PubMed / Full text
  • Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain. / 24.07.2018 / PubMed / Full text
  • Dual-Task Gait and Alzheimer's Disease Genetic Risk in Cognitively Normal Adults: A Pilot Study. / 2018 / PubMed / Full text
  • Higher Aortic Stiffness Is Related to Lower Cerebral Blood Flow and Preserved Cerebrovascular Reactivity in Older Adults. / 30.10.2018 / PubMed / Full text
  • Physical activity effects on the individual alpha peak frequency of older adults with and without genetic risk factors for Alzheimer's Disease: A MEG study. / 09.2018 / PubMed / Full text
  • Racial and Ethnic Disparities in Dementia Risk Among Individuals With Low Education. / 09.2018 / PubMed / Full text
  • Increased CAIDE dementia risk, cognition, CSF biomarkers, and vascular burden in healthy adults. / 17.07.2018 / PubMed / Full text
  • Differential 5-year brain atrophy rates in cognitively declining and stable APOE-ε4 elders. / 09.2018 / PubMed / Full text
  • Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. / 10.2018 / PubMed / Full text
  • Using event-related fMRI to examine sustained attention processes and effects of APOE ε4 in young adults. / 2018 / PubMed / Full text
  • Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age. / 2018 / PubMed / Full text
  • White matter microstructure is altered in cognitively normal middle-aged APOE-ε4 homozygotes. / 24.05.2018 / PubMed / Full text
  • Effects of lifetime cumulative ginseng intake on cognitive function in late life. / 24.05.2018 / PubMed / Full text
  • Apolipoprotein E region molecular signatures of Alzheimer's disease. / 08.2018 / PubMed / Full text
  • Does incipient dementia explain normal cognitive decline determinants? Lothian birth cohort 1921. / 06.2018 / PubMed / Full text
  • An 18-mo randomized, double-blind, placebo-controlled trial of DHA-rich fish oil to prevent age-related cognitive decline in cognitively normal older adults. / 01.05.2018 / PubMed / Full text
  • The Role of Apolipoprotein E and Ethanol Exposure in Age-Related Changes in Choline Acetyltransferase and Brain-Derived Neurotrophic Factor Expression in the Mouse Hippocampus. / 05.2018 / PubMed / Full text
  • APOE genotype modifies the association between central arterial stiffening and cognition in older adults. / 07.2018 / PubMed / Full text
  • Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration. / 2018 / PubMed / Full text
  • Brain Aging and APOE ε4 Interact to Reveal Potential Neuronal Compensation in Healthy Older Adults. / 2018 / PubMed / Full text
  • Leisure-Time Physical Activity and the Risk of Incident Dementia: The Mayo Clinic Study of Aging. / 2018 / PubMed / Full text
  • Effects of APOE-ε4 allele load on brain morphology in a cohort of middle-aged healthy individuals with enriched genetic risk for Alzheimer's disease. / 07.2018 / PubMed / Full text
  • APOE influences working memory in non-demented elderly through an interaction with SPON1 rs2618516. / 07.2018 / PubMed / Full text
  • Altered effective connectivity anchored in the posterior cingulate cortex and the medial prefrontal cortex in cognitively intact elderly APOE ε4 carriers: a preliminary study. / 02.2019 / PubMed / Full text
  • Plasma Cortisol, Brain Amyloid-β, and Cognitive Decline in Preclinical Alzheimer's Disease: A 6-Year Prospective Cohort Study. / 01.2017 / PubMed / Full text
  • Apolipoprotein E genotypes and longevity across dementia disorders. / 07.2018 / PubMed / Full text
  • Differential Effect of APOE ɛ4 Status and Elevated Pulse Pressure on Functional Decline in Cognitively Normal Older Adults. / 2018 / PubMed / Full text
  • Functional segregation loss over time is moderated by APOE genotype in healthy elderly. / 07.2018 / PubMed / Full text
  • Dementia Prevalence in Greece: The Hellenic Longitudinal Investigation of Aging and Diet (HELIAD). / 07-09.2018 / PubMed / Full text
  • Atypical Localization and Dissociation between Glucose Uptake and Amyloid Deposition in Cognitively Normal APOE*E4 Homozygotic Elders Compared with Patients with Late-Onset Alzheimer's Disease. / 01-02.2018 / PubMed / Full text
  • Association between subjective memory assessment and associative memory performance: Role of ad risk factors. / 02.2018 / PubMed / Full text
  • Reduced Gray Matter Volume of the Thalamus and Hippocampal Region in Elderly Healthy Adults with no Impact of APOE ɛ4: A Longitudinal Voxel-Based Morphometry Study. / 2018 / PubMed / Full text
  • Apolipoprotein E genotype does not moderate the associations of depressive symptoms, neuroticism and allostatic load with cognitive ability and cognitive aging in the Lothian Birth Cohort 1936. / 2018 / PubMed / Full text
  • A Network of Genetic Effects on Non-Demented Cognitive Aging: Alzheimer's Genetic Risk (CLU CR1   PICALM) Intensifies Cognitive Aging Genetic Risk (COMT BDNF) Selectively for APOEɛ4 Carriers. / 2018 / PubMed / Full text
  • Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text
  • Genetic Variation in FOXO3 is Associated with Self-Rated Health in a Population-Based Sample of Older Individuals. / 08.10.2018 / PubMed / Full text
  • APOE ε4 Genotype and Cognitive Reserve Effects on the Cognitive Functioning of Healthy Elders. / 2017 / PubMed / Full text
  • Distinct neural correlates of episodic memory among apolipoprotein E alleles in cognitively normal elderly. / 02.2019 / PubMed / Full text
  • Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis. / 06.12.2017 / PubMed / Full text
  • Features associated with cognitive impairment and dementia in a community-based sample of illiterate elderly aged 75 years: the Pietà study. / 04-06.2014 / PubMed / Full text
  • Epistasis, physical capacity-related genes and exceptional longevity: FNDC5 gene interactions with candidate genes FOXOA3 and APOE. / 14.11.2017 / PubMed / Full text
  • Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer's disease-like pathology. / 13.11.2017 / PubMed / Full text
  • Green space and cognitive ageing: A retrospective life course analysis in the Lothian Birth Cohort 1936. / 01.2018 / PubMed / Full text
  • Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations. / 23.10.2017 / PubMed / Full text
  • Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. / 13.10.2017 / PubMed / Full text
  • Phenome and genome based studies into human ageing and longevity: An overview. / 09.2018 / PubMed / Full text
  • A Tale of Two Genes: Microglial Apoe and Trem2. / 19.09.2017 / PubMed / Full text
  • The Association of Apolipoprotein E Gene Polymorphism With Cognitive Performance in Nondemented Polish Adults Aged 55 to 75. / 09.2018 / PubMed / Full text
  • Cognitive Aging in Black and White Americans: Cognition, Cognitive Decline, and Incidence of Alzheimer Disease Dementia. / 01.2018 / PubMed / Full text
  • Alzheimer's Disease Biomarkers Interactively Influence Physical Activity, Mobility, and Cognition Associations in a Non-Demented Aging Population. / 2017 / PubMed / Full text
  • Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort. / 2017 / PubMed / Full text
  • Putting attention in the spotlight: The influence of APOE genotype on visual search in mid adulthood. / 15.09.2017 / PubMed / Full text
  • Left Frontal Hub Connectivity during Memory Performance Supports Reserve in Aging and Mild Cognitive Impairment. / 2017 / PubMed / Full text
  • Physical activity modifies the influence of apolipoprotein E ε4 allele and type 2 diabetes on dementia and cognitive impairment among older Mexican Americans. / 01.2018 / PubMed / Full text
  • Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition. / 2017 / PubMed / Full text
  • Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults. / 03.07.2017 / PubMed / Full text
  • Differential Aging Trajectories of Modulation of Activation to Cognitive Challenge in APOE ε4 Groups: Reduced Modulation Predicts Poorer Cognitive Performance. / 19.07.2017 / PubMed / Full text
  • Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults. / 09.2017 / PubMed / Full text
  • APOE gene polymorphism in long-lived individuals from a central China population. / 12.06.2017 / PubMed / Full text
  • Disrupted white matter structural networks in healthy older adult APOE ε4 carriers - An international multicenter DTI study. / 15.08.2017 / PubMed / Full text
  • Effect of APOE ε4 Genotype on Metabolic Biomarkers in Aging and Alzheimer's Disease. / 2017 / PubMed / Full text
  • APOE moderates compensatory recruitment of neuronal resources during working memory processing in healthy older adults. / 08.2017 / PubMed / Full text
  • General cognitive status among Baby boomers and pre-boomers in Taiwan: the interplay between mid-life socioeconomic status and city residence. / 25.05.2017 / PubMed / Full text
  • APOE ε4 Modulation of Training Outcomes in Several Cognitive Domains in a Sample of Cognitively Intact Older Adults. / 2017 / PubMed / Full text
  • APOE Genotype and Nonrespiratory Sleep Parameters in Cognitively Intact Older Adults. / 01.08.2017 / PubMed / Full text
  • The APOE ε4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease. / 19.07.2017 / PubMed / Full text
  • Cognitive Domain Dispersion Association with Alzheimer's Disease Pathology. / 2017 / PubMed / Full text
  • Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals. / 01.06.2017 / PubMed / Full text
  • Plasma apolipoproteins and physical and cognitive health in very old individuals. / 07.2017 / PubMed / Full text
  • Youthful Processing Speed in Older Adults: Genetic, Biological, and Behavioral Predictors of Cognitive Processing Speed Trajectories in Aging. / 2017 / PubMed / Full text
  • Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases. / 01.04.2017 / PubMed / Full text
  • Aberrant interhemispheric functional connectivity within default mode network and its relationships with neurocognitive features in cognitively normal APOE ε 4 elderly carriers. / 05.2017 / PubMed / Full text
  • Association between tau deposition and antecedent amyloid-β accumulation rates in normal and early symptomatic individuals. / 01.05.2017 / PubMed / Full text
  • Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73 to 76. / 06.2017 / PubMed / Full text
  • Convergent and divergent effects of apolipoprotein E ε4 and ε2 alleles on amygdala functional networks in nondemented older adults. / 06.2017 / PubMed / Full text
  • Effect of age and the APOE gene on metabolite concentrations in the posterior cingulate cortex. / 15.05.2017 / PubMed / Full text
  • Modulation of Retinal Arteriolar Central Reflection by APOE Genotype. / 2017 / PubMed / Full text
  • Prospective associations of exercise and depressive symptoms in older adults: the role of apolipoprotein E4. / 07.2017 / PubMed / Full text
  • Psychosocial Risk and Protective Factors and Incident Mild Cognitive Impairment and Dementia in Community Dwelling Elderly: Findings from the Singapore Longitudinal Ageing Study. / 2017 / PubMed / Full text
  • Demographic, phenotypic, and genetic characteristics of centenarians in Okinawa and Honshu, Japan: Part 2 Honshu, Japan. / 07.2017 / PubMed / Full text
  • Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
  • CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN. / 04.2017 / PubMed / Full text
  • Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old. / 28.03.2017 / PubMed / Full text
  • A Multi-Cohort Study of ApoE ɛ4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease. / 2017 / PubMed / Full text
  • The rs1277306 Variant of the REST Gene Confers Susceptibility to Cognitive Aging in an Elderly Taiwanese Population. / 2017 / PubMed / Full text
  • The Interactive Effects of Age and PICALM rs541458 Polymorphism on Cognitive Performance, Brain Structure, and Function in Non-demented Elderly. / 02.2018 / PubMed / Full text
  • Age differences in arterial and venous extra-cerebral blood flow in healthy adults: contributions of vascular risk factors and genetic variants. / 08.2017 / PubMed / Full text
  • High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors. / 01.2017 / PubMed / Full text
  • Executive function performance and change in aging is predicted by apolipoprotein E, intensified by catechol-O-methyltransferase and brain-derived neurotrophic factor, and moderated by age and lifestyle. / 04.2017 / PubMed / Full text
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  • Motor timing intraindividual variability in amnestic mild cognitive impairment and cognitively intact elders at genetic risk for Alzheimer's disease. / 11.2017 / PubMed / Full text
  • Screening Younger Individuals in a Primary Care Setting Flags Putative Dementia Cases and Correlates Gastrointestinal Diseases with Poor Cognitive Performance. / 2017 / PubMed / Full text
  • The integration of epigenetics and genetics in nutrition research for CVD risk factors. / 08.2017 / PubMed / Full text
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  • Association of Brain Amyloid-β With Slow Gait in Elderly Individuals Without Dementia: Influence of Cognition and Apolipoprotein E ε4 Genotype. / 01.01.2017 / PubMed / Full text
  • Effect of the Interplay Between Genetic and Behavioral Risks on Survival After Age 75. / 12.2016 / PubMed / Full text
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  • Comparison of Gait Parameters for Predicting Cognitive Decline: The Mayo Clinic Study of Aging. / 2017 / PubMed / Full text
  • The APOE paradox: do attentional control differences in mid-adulthood reflect risk of late-life cognitive decline. / 12.2016 / PubMed / Full text
  • Relative effect of APOE ε4 on neuroimaging biomarker changes across the lifespan. / 18.10.2016 / PubMed / Full text
  • The Effects of an APOE Promoter Polymorphism on Human White Matter Connectivity during Non-Demented Aging. / 2017 / PubMed / Full text
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  • Precuneus degeneration in nondemented elderly individuals with APOE ɛ4: Evidence from structural and functional MRI analyses. / 01.2017 / PubMed / Full text
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  • Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. / 2016 / PubMed / Full text
  • Mixed brain lesions mediate the association between cardiovascular risk burden and cognitive decline in old age: A population-based study. / 03.2017 / PubMed / Full text
  • Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age. / 08.2016 / PubMed / Full text
  • Neuritic and Diffuse Plaque Associations with Memory in Non-Cognitively Impaired Elderly. / 14.07.2016 / PubMed / Full text
  • White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration. / 2016 / PubMed / Full text
  • APOE ε4 allele modifies the association of lead exposure with age-related cognitive decline in older individuals. / 11.2016 / PubMed / Full text
  • APOE genotype and stress response - a mini review. / 25.07.2016 / PubMed / Full text
  • An Alzheimer's Disease Genetic Risk Score Predicts Longitudinal Thinning of Hippocampal Complex Subregions in Healthy Older Adults. / 05-06.2016 / PubMed / Full text
  • Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort. / 12.2016 / PubMed / Full text
  • FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. / 14.07.2016 / PubMed / Full text
  • Affect of APOE on information processing speed in non-demented elderly population: a preliminary structural MRI study. / 08.2017 / PubMed / Full text
  • Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy. / 15.10.2016 / PubMed / Full text
  • The effect of β-amyloid positivity on cerebral metabolism in cognitively normal seniors. / 12.2016 / PubMed / Full text
  • The Effect of the APOE Genotype on Individual BrainAGE in Normal Aging, Mild Cognitive Impairment, and Alzheimer's Disease. / 2016 / PubMed / Full text
  • Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice. / 12.07.2016 / PubMed / Full text
  • Gray matter maturation and cognition in children with different APOE ε genotypes. / 09.08.2016 / PubMed / Full text
  • The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and APOE. / 02.08.2016 / PubMed / Full text
  • Impact of Personality on Cognitive Aging: A Prospective Cohort Study. / 08.2016 / PubMed / Full text
  • Changes in Frailty Predict Changes in Cognition in Older Men: The Honolulu-Asia Aging Study. / 15.06.2016 / PubMed / Full text
  • APOE and aging-related cognitive change in a longitudinal cohort of men. / 08.2016 / PubMed / Full text
  • Braak stage and trajectory of cognitive decline in noncognitively impaired elders. / 07.2016 / PubMed / Full text
  • Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models. / 30.03.2017 / PubMed / Full text
  • Global hypoxia induced impairment in learning and spatial memory is associated with precocious hippocampal aging. / 09.2016 / PubMed / Full text
  • Selective familiarity deficits in otherwise cognitively intact aging individuals with genetic risk for Alzheimer's disease. / 2016 / PubMed / Full text
  • Blood glucose levels and cortical thinning in cognitively normal, middle-aged adults. / 15.06.2016 / PubMed / Full text
  • Relationship between APOE Genotype and Structural MRI Measures throughout Adulthood in the Study of Health in Pomerania Population-Based Cohort. / 09.2016 / PubMed / Full text
  • Waist circumference is correlated with poorer cognition in elderly type 2 diabetes women. / 08.2016 / PubMed / Full text
  • Risk-reducing Apolipoprotein E and Clusterin genotypes protect against the consequences of poor vascular health on executive function performance and change in nondemented older adults. / 06.2016 / PubMed / Full text
  • Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants. / 07.2016 / PubMed / Full text
  • APOE4 Induces Site-Specific Tau Phosphorylation Through Calpain-CDK5 Signaling Pathway in EFAD-Tg Mice. / 2016 / PubMed / Full text
  • Cardiometabolic risk factors predict cerebrovascular health in older adults: results from the Brain in Motion study. / 04.2016 / PubMed / Full text
  • Dementia Risk and Protective Factors Differ in the Context of Memory Trajectory Groups. / 12.04.2016 / PubMed / Full text
  • Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan. / 31.03.2016 / PubMed / Full text
  • Age, APOE and sex: Triad of risk of Alzheimer's disease. / 06.2016 / PubMed / Full text
  • Occupational cognitive requirements and late-life cognitive aging. / 12.04.2016 / PubMed / Full text
  • Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease. / 05.2016 / PubMed / Full text
  • Genetic landscape of APOE in human longevity revealed by high-throughput sequencing. / 04.2016 / PubMed / Full text
  • No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes. / 06.2016 / PubMed / Full text
  • Lack of neural compensatory mechanisms of BDNF val66met met carriers and APOE E4 carriers in healthy aging, mild cognitive impairment, and Alzheimer's disease. / 03.2016 / PubMed / Full text
  • Novel loci and pathways significantly associated with longevity. / 25.02.2016 / PubMed / Full text
  • White matter hyperintensities and imaging patterns of brain ageing in the general population. / 04.2016 / PubMed / Full text
  • Characterization of Amyloid-β Deposits in Bovine Brains. / 2016 / PubMed / Full text
  • The role of APOE in cerebrovascular dysfunction. / 05.2016 / PubMed / Full text
  • Decreased Inter-Hemispheric Functional Connectivity in Cognitively Intact Elderly APOE ɛ4 Carriers: A Preliminary Study. / 2016 / PubMed / Full text
  • APOE ε4 associated with preserved executive function performance and maintenance of temporal and cingulate brain volumes in younger adults. / 02.2017 / PubMed / Full text
  • [GENETIC AND EPIGENETIC DETERMINANTS OF ALZHEIMER'S DISEASE]. / 2015 / PubMed
  • Olfactory memory in the old and very old: relations to episodic and semantic memory and APOE genotype. / 02.2016 / PubMed / Full text
  • The APOE epsilon 4 polymorphism does not predict late onset depression: the Three-City Study. / 04.2016 / PubMed / Full text
  • High homocysteine and epistasis between MTHFR and APOE: association with cognitive performance in the elderly. / 04.2016 / PubMed / Full text
  • The Relationship Between Plasma Aβ Levels, Cognitive Function and Brain Volumetrics: Sydney Memory and Ageing Study. / 2016 / PubMed / Full text
  • Braak staging, plaque pathology, and APOE status in elderly persons without cognitive impairment. / 01.2016 / PubMed / Full text
  • Biomarkers of cholesterol homeostasis in a clinical laboratory database sample comprising 667,718 patients. / 11-12.2015 / PubMed / Full text
  • Genetic factors and epigenetic mechanisms of longevity: current perspectives. / 2015 / PubMed / Full text
  • Subjective Memory Complaints in APOEɛ4 Carriers are Associated with High Amyloid-β Burden. / 2016 / PubMed / Full text
  • Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: the modulating effects of older age and disease severity. / 2013 / PubMed / Full text
  • Individual estimates of age at detectable amyloid onset for risk factor assessment. / 04.2016 / PubMed / Full text
  • Influence of amyloid and APOE on cognitive performance in a late middle-aged cohort. / 03.2016 / PubMed / Full text
  • Gene-Environment Interplay in Physical, Psychological, and Cognitive Domains in Mid to Late Adulthood: Is APOE a Variability Gene? / 01.2016 / PubMed / Full text
  • Predictors of Cognitive and Functional Decline in Patients With Alzheimer Disease Dementia From Brazil. / 07-09.2016 / PubMed / Full text
  • APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction. / 10.2015 / PubMed / Full text
  • Association of APOE with tau-tangle pathology with and without β-amyloid. / 01.2016 / PubMed / Full text
  • APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration. / 07.10.2015 / PubMed / Full text
  • The Role of Alzheimer's and Cerebrovascular Pathology in Mediating the Effects of Age, Race, and Apolipoprotein E Genotype on Dementia Severity in Pathologically-Confirmed Alzheimer's Disease. / 2016 / PubMed / Full text
  • [SOME RESULTS OF MOLECULAR GENETIC RESEARCHES OF AGING AND LONGEVITY]. / 2015 / PubMed
  • Ankle-Brachial Index but Neither Intima Media Thickness Nor Coronary Artery Calcification is Associated With Mild Cognitive Impairment. / 2015 / PubMed / Full text
  • No difference in paired associative stimulation induced cortical neuroplasticity between patients with mild cognitive impairment and elderly controls. / 02.2016 / PubMed / Full text
  • Comparison of ApoE-related brain connectivity differences in early MCI and normal aging populations: an fMRI study. / 12.2016 / PubMed / Full text
  • Effects of APOE rs429358, rs7412 and GSTM1/GSTT1 Polymorphism on Plasma and Erythrocyte Antioxidant Parameters and Cognition in Old Chinese Adults. / 24.09.2015 / PubMed / Full text
  • Does apolipoprotein E genotype influence cognition in middle-aged individuals? / 12.2015 / PubMed / Full text
  • Diabetes is Associated with Worse Executive Function in Both Eastern and Western Populations: Shanghai Aging Study and Mayo Clinic Study of Aging. / 2015 / PubMed / Full text
  • APOE Affects the Volume and Shape of the Amygdala and the Hippocampus in Mild Cognitive Impairment and Alzheimer's Disease: Age Matters. / 2015 / PubMed / Full text
  • APOE-by-sex interactions on brain structure and metabolism in healthy elderly controls. / 29.09.2015 / PubMed / Full text
  • APOE Genotype Affects Cognitive Training Response in Healthy Shanghai Community-Dwelling Elderly Individuals. / 2015 / PubMed / Full text
  • Association of White Matter Integrity and Cognitive Functions in Chinese Non-Demented Elderly with the APOE ɛ4 Allele. / 2015 / PubMed / Full text
  • Vascular Health and Genetic Risk Affect Mild Cognitive Impairment Status and 4-Year Stability: Evidence From the Victoria Longitudinal Study. / 11.2016 / PubMed / Full text
  • Apolipoprotein E and Clusterin can magnify effects of personality vulnerability on declarative memory performance in non-demented older adults. / 05.2016 / PubMed / Full text
  • Examining the association between Apolipoprotein E (APOE) and self-reported sleep disturbances in non-demented older adults. / 08.10.2015 / PubMed / Full text
  • G×E Interaction Influences Trajectories of Hand Grip Strength. / 01.2016 / PubMed / Full text
  • Effects of APOE promoter polymorphism on the topological organization of brain structural connectome in nondemented elderly. / 12.2015 / PubMed / Full text
  • Interactive effects of physical activity and APOE-ε4 on white matter tract diffusivity in healthy elders. / 01.05.2016 / PubMed / Full text
  • Brain Amyloid Deposition and Longitudinal Cognitive Decline in Nondemented Older Subjects: Results from a Multi-Ethnic Population. / 2015 / PubMed / Full text
  • DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) genes are associated with anxiety/depression in older women. / 2015 / PubMed / Full text
  • Longitudinal cognitive decline in the AIBL cohort: The role of APOE ε4 status. / 08.2015 / PubMed / Full text
  • Anterior cingulate cortex mediates the relationship between O3PUFAs and executive functions in APOE e4 carriers. / 2015 / PubMed / Full text
  • Current versus lifetime depression, APOE variation, and their interaction on cognitive performance in younger and older adults. / 06.2015 / PubMed / Full text
  • Aging, Practice Effects, and Genetic Risk in the Wisconsin Registry for Alzheimer's Prevention. / 2015 / PubMed / Full text
  • Glucose Dysregulation Interacts With APOE-∊4 to Potentiate Temporoparietal Cortical Thinning. / 02.2016 / PubMed / Full text
  • Spatial pattern separation differences in older adult carriers and non-carriers for the apolipoprotein E epsilon 4 allele. / 03.2016 / PubMed / Full text
  • GWAS and Meta-Analysis in Aging/Longevity. / 2015 / PubMed / Full text
  • Odor identification and Alzheimer disease biomarkers in clinically normal elderly. / 26.05.2015 / PubMed / Full text
  • Aging, Alzheimer's, and APOE genotype influence the expression and neuronal distribution patterns of microtubule motor protein dynactin-P50. / 2015 / PubMed / Full text
  • Interaction of Cigarette Smoking History With APOE Genotype and Age on Amyloid Level, Glucose Metabolism, and Neurocognition in Cognitively Normal Elders. / 02.2016 / PubMed / Full text
  • APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice. / 05.03.2015 / PubMed / Full text
  • APOE ε4 Genotype and the Risk for Subjective Cognitive Impairment in Elderly Persons. / Fall.2015 / PubMed / Full text
  • Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of Aging. / 07.04.2015 / PubMed / Full text
  • The identification of cognitive subtypes in Alzheimer's disease dementia using latent class analysis. / 03.2016 / PubMed / Full text
  • Age, Sex, and APOE ε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span. / 05.2015 / PubMed / Full text
  • Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults. / 2015 / PubMed / Full text
  • Bone mineral density, adiposity, and cognitive functions. / 2015 / PubMed / Full text
  • Buccal cell cytokeratin 14 identifies mild cognitive impairment and Alzheimer' s disease in the AIBL study of aging. / 2015 / PubMed / Full text
  • Traumatic brain injury and late-life dementia. / 2015 / PubMed / Full text
  • Are the effects of APOE ϵ4 on cognitive function in nonclinical populations age- and gender-dependent? / 2015 / PubMed / Full text
  • Interactive effect of APOE genotype and blood pressure on cognitive decline: the PATH through life study. / 2015 / PubMed / Full text
  • Sex-based memory advantages and cognitive aging: a challenge to the cognitive reserve construct? / 02.2015 / PubMed / Full text
  • DNA methylation age of blood predicts all-cause mortality in later life. / 30.01.2015 / PubMed / Full text
  • The effects of an APOE promoter polymorphism on human cortical morphology during nondemented aging. / 28.01.2015 / PubMed / Full text
  • Cognitive resilience to apolipoprotein E ε4: contributing factors in black and white older adults. / 03.2015 / PubMed / Full text
  • Innovative Research Design Exploring the Effects of Physical Activity and Genetics on Cognitive Performance in Community-Based Older Adults. / 10.2015 / PubMed / Full text
  • Buying time: a rationale for examining the use of circadian rhythm and sleep interventions to delay progression of mild cognitive impairment to Alzheimer's disease. / 2014 / PubMed / Full text
  • Genetic variants modify the effect of age on APOE methylation in the Genetics of Lipid Lowering Drugs and Diet Network study. / 02.2015 / PubMed / Full text
  • Genetic factors associated with longevity: a review of recent findings. / 01.2015 / PubMed / Full text
  • Telomerase Gene (hTERT) and Survival: Results From Two Swedish Cohorts of Older Adults. / 02.2016 / PubMed / Full text
  • Epidemic spreading model to characterize misfolded proteins propagation in aging and associated neurodegenerative disorders. / 11.2014 / PubMed / Full text
  • Correcting Bias Caused by Missing Data in the Estimate of the Effect of Apolipoprotein ε4 on Cognitive Decline. / 01.2015 / PubMed / Full text
  • The Shanghai Aging Study: study design, baseline characteristics, and prevalence of dementia. / 2014 / PubMed / Full text
  • Opposite Neural Trajectories of Apolipoprotein E ϵ4 and ϵ2 Alleles with Aging Associated with Different Risks of Alzheimer's Disease. / 04.2016 / PubMed / Full text
  • Resting-state functional connectivity changes in aging apoE4 and apoE-KO mice. / 15.10.2014 / PubMed / Full text
  • Disease variants in genomes of 44 centenarians. / 09.2014 / PubMed / Full text
  • Longitudinal trajectories of cholesterol from midlife through late life according to apolipoprotein E allele status. / 16.10.2014 / PubMed / Full text
  • Influence of the APOE ε4 allele and mild cognitive impairment diagnosis in the disruption of the MEG resting state functional connectivity in sources space. / 2015 / PubMed / Full text
  • Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity? / 23.09.2014 / PubMed / Full text
  • Self-reported memory complaints: implications from a longitudinal cohort with autopsies. / 07.10.2014 / PubMed / Full text
  • The interaction of APOE genotype by age in amnestic mild cognitive impairment: a voxel-based morphometric study. / 2015 / PubMed / Full text
  • APOE ε4 allele is associated with worse performance in memory dimensions of the mini-mental state examination: the Bambuí Cohort Study of Aging. / 06.2015 / PubMed / Full text
  • Influence of multiple APOE genetic variants on cognitive function in a cohort of older men - results from the Normative Aging Study. / 01.08.2014 / PubMed / Full text
  • Source analysis of spontaneous magnetoencephalograpic activity in healthy aging and mild cognitive impairment: influence of apolipoprotein E polymorphism. / 2015 / PubMed / Full text
  • Effect of leukocyte telomere length on total and regional brain volumes in a large population-based cohort. / 10.2014 / PubMed / Full text
  • Associations between APOE and low-density lipoprotein cholesterol genotypes and cognitive and physical capability: the HALCyon programme. / 2014 / PubMed / Full text
  • Can education rescue genetic liability for cognitive decline? / 02.2015 / PubMed / Full text
  • Dietary patterns and cognitive decline in an Australian study of ageing. / 07.2015 / PubMed / Full text
  • Association of lifetime intellectual enrichment with cognitive decline in the older population. / 08.2014 / PubMed / Full text
  • Associations between apolipoprotein E genotypes and serum levels of glucose, cholesterol, and triglycerides in a cognitively normal aging Han Chinese population. / 2014 / PubMed / Full text
  • Aging and age-related diseases--from endocrine therapy to target therapy. / 25.08.2014 / PubMed / Full text
  • Lack of effect of the apolipoprotein E ε4 genotype on cognition during healthy aging. / 2014 / PubMed / Full text
  • Risk factors that affect life expectancy in Alzheimer's disease: a 15-year follow-up. / 2014 / PubMed / Full text
  • Structure and correlates of cognitive aging in a narrow age cohort. / 06.2014 / PubMed / Full text
  • Gene-environment interactions: lifetime cognitive activity, APOE genotype, and β-amyloid burden. / 18.06.2014 / PubMed / Full text
  • Hypertension moderates the effect of APOE on 21-year cognitive trajectories. / 06.2014 / PubMed / Full text
  • APOE and BDNF Val66Met polymorphisms combine to influence episodic memory function in older adults. / 01.09.2014 / PubMed / Full text
  • Genetic variants in PVRL2-TOMM40-APOE region are associated with human longevity in a Han Chinese population. / 2014 / PubMed / Full text
  • Life experience and demographic influences on cognitive function in older adults. / 11.2014 / PubMed / Full text
  • APOE-epsilon4 and aging of medial temporal lobe gray matter in healthy adults older than 50 years. / 11.2014 / PubMed / Full text
  • Apolipoprotein E Allele and Hearing Thresholds in Older Adults. / 02.2016 / PubMed / Full text
  • Differential clinicopathologic and genetic features of late-onset amnestic dementias. / 09.2014 / PubMed / Full text
  • Late-life cynical distrust, risk of incident dementia, and mortality in a population-based cohort. / 17.06.2014 / PubMed / Full text
  • Longitudinal change in working memory as a function of APOE genotype in midlife and old age. / 06.2014 / PubMed / Full text
  • APOE moderates the association between lifestyle activities and cognitive performance: evidence of genetic plasticity in aging. / 05.2014 / PubMed / Full text
  • Effects of APOE ε4, age, and HIV on glial metabolites and cognitive deficits. / 17.06.2014 / PubMed / Full text
  • Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals. / 09.2014 / PubMed / Full text
  • Association of hypometabolism and amyloid levels in aging, normal subjects. / 03.06.2014 / PubMed / Full text
  • Association of apolipoprotein E-e4 and dementia declines with age. / 10.2014 / PubMed / Full text
  • No evidence of a longitudinal association between diurnal cortisol patterns and cognition. / 10.2014 / PubMed / Full text
  • Gene-gene interaction between CETP and APOE polymorphisms confers higher risk for hypertriglyceridemia in oldest-old Chinese women. / 07.2014 / PubMed / Full text
  • Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease. / 20.05.2014 / PubMed / Full text
  • Differences in age-related effects on brain volume in Down syndrome as compared to Williams syndrome and typical development. / 2014 / PubMed / Full text
  • 18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons. / 09.2014 / PubMed / Full text
  • ACE polymorphism and use of ACE inhibitors: effects on memory performance. / 06.2014 / PubMed / Full text
  • Exercise, APOE genotype, and the evolution of the human lifespan. / 05.2014 / PubMed / Full text
  • Long-term cognitive correlates of traumatic brain injury across adulthood and interactions with APOE genotype, sex, and age cohorts. / 04.2014 / PubMed / Full text
  • The benefits of staying active in old age: physical activity counteracts the negative influence of PICALM, BIN1, and CLU risk alleles on episodic memory functioning. / 06.2014 / PubMed / Full text
  • Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. / 2014 / PubMed / Full text
  • Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculature. / 21.03.2014 / PubMed / Full text
  • [Clinical and genetic characteristics of long-livers in Moscow region]. / 2013 / PubMed
  • Cortical ¹¹C-PIB uptake is associated with age, APOE genotype, and gender in "healthy aging". / 2014 / PubMed / Full text
  • Prevalence of mild cognitive impairment in an urban community in China: a cross-sectional analysis of the Shanghai Aging Study. / 03.2015 / PubMed / Full text
  • Cognitive and neural signatures of the APOE E4 allele in mid-aged adults. / 07.2014 / PubMed / Full text
  • Mitochondrial DNA and traumatic brain injury. / 02.2014 / PubMed / Full text
  • The APOE ε4 allele in relation to brain white-matter microstructure in adulthood and aging. / 06.2014 / PubMed / Full text
  • Stress, race, and APOE: understanding the interplay of risk factors for changes in cognitive functioning. / 2014 / PubMed / Full text
  • Beta-amyloid associated differential effects of APOE ε4 on brain metabolism in cognitively normal elderly. / 10.2014 / PubMed / Full text
  • Apolipoprotein E and depressive symptoms: shared or independent routes to age-related cognitive decline? / 02.2014 / PubMed / Full text
  • Interaction of APOE genotype and testosterone on episodic memory in middle-aged men. / 07.2014 / PubMed / Full text
  • Sydney Memory and Ageing Study: an epidemiological cohort study of brain ageing and dementia. / 12.2013 / PubMed / Full text
  • Basal forebrain atrophy and cortical amyloid deposition in nondemented elderly subjects. / 10.2014 / PubMed / Full text
  • Interactive effects of apolipoprotein E4 and diabetes risk on later myelinating white matter regions in neurologically healthy older aged adults. / 05.2014 / PubMed / Full text

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  • Cardiovascular Benefits of Endurance Training in Seniors: 40 is not too Late to Start. / 07.2016 / PubMed / Full text
  • Objectively Verified Parental Hip Fracture Is an Independent Risk Factor for Fracture: a Linkage Analysis of 478,792 Parents and 261,705 Offspring. / 09.2016 / PubMed / Full text
  • Maximum bite force at age 70 years predicts all-cause mortality during the following 13 years in Japanese men. / 08.2016 / PubMed / Full text
  • Frailty as a Predictor of Institutionalization Among Adults With Intellectual and Developmental Disabilities. / 04.2016 / PubMed / Full text
  • Recent trends in life expectancy for people with type 1 diabetes in Sweden. / 06.2016 / PubMed / Full text
  • A Global View on the Effects of Work on Health in Later Life. / 04.2016 / PubMed / Full text
  • Comparison of bioenergetics of walking during a multistage incremental shuttle walk test and a 6-min walk test in active older adults. / 04.2017 / PubMed / Full text
  • Effect of valsartan on cardiac senescence and apoptosis in a rat model of cardiotoxicity. / 06.2016 / PubMed / Full text
  • Frailty as a predictor of hospitalisation among community-dwelling older people: a systematic review and meta-analysis. / 07.2016 / PubMed / Full text
  • Reaction Time Measures Predict Incident Dementia in Community-Living Older Adults: The Sydney Memory and Ageing Study. / 03.2016 / PubMed / Full text
  • Quantitative Scheimpflug camera study of the lens density in healthy Turkish population. / 12.2016 / PubMed / Full text
  • Comparison of heart rate changes with ictal tachycardia seizures in adults and children. / 04.2016 / PubMed / Full text
  • The Influence of Age and Central Foveal Thickness on Foveal Zone Size in Healthy People. / 02.2016 / PubMed / Full text
  • Natural history of age-related lobular involution and impact on breast cancer risk. / 02.2016 / PubMed / Full text
  • Long-term Cognitive Trajectories and Mortality in Older Women. / 08.2016 / PubMed / Full text
  • Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study. / 03.2016 / PubMed / Full text
  • How are neuroticism and depression related to the psychophysiological stress response to acute stress in healthy older people? / 15.03.2016 / PubMed / Full text
  • A novel technique to investigate the effect of ageing on ventricular repolarization characteristics in healthy and LQTS subjects. / 08.2015 / PubMed / Full text
  • Age-dependent prognostic value of exercise capacity and derivation of fitness-associated biologic age. / 03.2016 / PubMed / Full text
  • Muscle Quality and Myosteatosis: Novel Associations With Mortality Risk: The Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study. / 01.01.2016 / PubMed / Full text
  • Long-term UVA eye irradiation causes decreased learning ability in mice. / 05.2016 / PubMed / Full text
  • Smoking status and life expectancy after acute myocardial infarction in the elderly. / 01.2016 / PubMed / Full text
  • Hypogonadism and Mortality in Aged Hospitalized Male Patients: A 5-Year Prospective Observational Study. / 11.2015 / PubMed / Full text
  • Social network typologies and mortality risk among older people in China, India, and Latin America: A 10/66 Dementia Research Group population-based cohort study. / 12.2015 / PubMed / Full text
  • Age-related changes in bone strength from HR-pQCT derived microarchitectural parameters with an emphasis on the role of cortical porosity. / 02.2016 / PubMed / Full text
  • Beta-Adrenergic Blockade Therapy for Autonomic Dysfunction is Less Effective for Elderly Patients with Heart Failure and Reduced Left Ventricular Ejection Fraction. / 2015 / PubMed / Full text
  • The Association of Reproductive Hormone Levels and All-Cause, Cancer, and Cardiovascular Disease Mortality in Men. / 12.2015 / PubMed / Full text
  • Advanced Age, High β-CTX Levels, and Impaired Renal Function are Independent Risk Factors for All-Cause One-Year Mortality in Hip Fracture Patients. / 01.2016 / PubMed / Full text
  • Aging augments renal vasoconstrictor response to orthostatic stress in humans. / 15.12.2015 / PubMed / Full text
  • The SIRT1 promoter polymorphic site rs12778366 increases IL-6 related human mortality in the prospective study "Treviso Longeva (TRELONG)". / 2015 / PubMed / Full text
  • Sleeve Gastrectomy Decreases Body Weight, Whole-Body Adiposity, and Blood Pressure Even in Aged Diet-Induced Obese Rats. / 07.2016 / PubMed / Full text
  • Associations of obesity and body fat distribution with incident atrial fibrillation in the biracial health aging and body composition cohort of older adults. / 09.2015 / PubMed / Full text
  • Food Habits, Lifestyle Factors and Mortality among Oldest Old Chinese: The Chinese Longitudinal Healthy Longevity Survey (CLHLS). / 09.09.2015 / PubMed / Full text
  • Age- and Gender-related Disparities in Primary Percutaneous Coronary Interventions for Acute ST-segment elevation Myocardial Infarction. / 2015 / PubMed / Full text
  • Functional measures, inflammatory markers and endothelin-1 as predictors of 360-day survival in centenarians. / 10.2015 / PubMed / Full text
  • Low-frequency oscillations in cerebrovascular and cardiovascular hemodynamics: Their interrelationships and the effect of age. / 11.2015 / PubMed / Full text
  • Testing a modified perceived exertion scale for Alzheimer's disease. / 03.2015 / PubMed / Full text
  • High Cardiorespiratory Fitness Levels Slow the Decline in Peak Heart Rate with Age. / 01.2016 / PubMed / Full text
  • Sex and age effects on cardiovascular autonomic function in healthy adults. / 10.2015 / PubMed / Full text
  • Role of endocortical contouring methods on precision of HR-pQCT-derived cortical micro-architecture in postmenopausal women and young adults. / 02.2016 / PubMed / Full text
  • History of previous bleeding and C-reactive protein improve assessment of bleeding risk in elderly patients (≥ 80 years) with myocardial infarction. / 11.2015 / PubMed / Full text
  • Use of serum albumin and activities of daily living to predict mortality in long-lived individuals over 95 years of age: a population-based study. / 08.2015 / PubMed / Full text
  • Pyridostigmine enhances atrial tachyarrhythmias in aging spontaneously hypertensive rats. / 10.2015 / PubMed / Full text
  • Low heel ultrasound parameters predict mortality in men: results from the European Male Ageing Study (EMAS). / 09.2015 / PubMed / Full text
  • Regulation of Cardiac Autonomic Nervous System Control across Frailty Statuses: A Systematic Review. / 2015 / PubMed / Full text
  • Anti-mullerian hormone (AMH) is associated with natural menopause in a population-based sample: The CARDIA Women's Study. / 08.2015 / PubMed / Full text
  • Dose-dependent effect of androgen deprivation therapy for localized prostate cancer on adverse cardiac events. / 08.2016 / PubMed / Full text
  • Ischemic heart disease, prescription of optimal medical therapy and geriatric syndromes in community-dwelling older men: A population-based study. / 01.08.2015 / PubMed / Full text
  • Gait characteristics and sensory abilities of older adults are modulated by gender. / 06.2015 / PubMed / Full text
  • Severity of depressive symptoms as a predictor of mortality: the English longitudinal study of ageing. / 10.2015 / PubMed / Full text
  • Higher Intake of Fruit, but Not Vegetables or Fiber, at Baseline Is Associated with Lower Risk of Becoming Overweight or Obese in Middle-Aged and Older Women of Normal BMI at Baseline. / 05.2015 / PubMed / Full text
  • Effect of a community intervention programme promoting social interactions on functional disability prevention for older adults: propensity score matching and instrumental variable analyses, JAGES Taketoyo study. / 09.2015 / PubMed / Full text
  • Comparison of cyclic and impact-based reference point indentation measurements in human cadaveric tibia. / 01.2018 / PubMed / Full text
  • Association of dialysis with the risks of cancers. / 2015 / PubMed / Full text
  • Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver. / 03.2015 / PubMed / Full text
  • Higher circulating adiponectin levels are associated with increased risk of atrial fibrillation in older adults. / 09.2015 / PubMed / Full text
  • Age-related changes in thirst, salt appetite, and arterial blood pressure in response to aldosterone-dexamethasone combination in rats. / 15.05.2015 / PubMed / Full text
  • Undertreatment of Men in Their Seventies with High-risk Nonmetastatic Prostate Cancer. / 07.2015 / PubMed / Full text
  • Anthropometric indices and dietary intake: prospective determinants of geriatric cognitive impairment? / 04.2013 / PubMed / Full text
  • 'Carriers of variant luteinizing hormone (V-LH) among 1593 Baltic men have significantly higher serum LH'. / 05.2015 / PubMed / Full text
  • Impact of living alone on institutionalization and mortality: a population-based longitudinal study. / 02.2016 / PubMed / Full text
  • [Normal values for high-resolution anorectal manometry in a healthy women: effects of age and maternity]. / 2014 / PubMed
  • A comparison of risperidone and haloperidol for the risk of ischemic stroke in the elderly: a propensity score-matched cohort analysis. / 08.2015 / PubMed / Full text
  • Inhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity. / 03.2015 / PubMed / Full text
  • Conservation of pro-longevity genes among mammals. / 03.2015 / PubMed / Full text
  • Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture risk in older adults: the Age, Gene/Environment Susceptibility Study. / 05.2015 / PubMed / Full text
  • Health related quality of life and perception of stigmatisation in adolescents living with sickle cell disease in Nigeria: A cross sectional study. / 07.2015 / PubMed / Full text
  • Bioidentical hormones, menopausal women, and the lure of the "natural" in U.S. anti-aging medicine. / 05.2015 / PubMed / Full text
  • Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. / 07.2015 / PubMed / Full text
  • Do Arterial Hemodynamic Parameters Predict Cognitive Decline Over a Period of 2 Years in Individuals Older Than 80 Years Living in Nursing Homes? The PARTAGE Study. / 01.07.2015 / PubMed / Full text
  • Providing instrumental social support is more beneficial to reduce mortality risk among the elderly with low educational level in Taiwan: a 12-year follow-up national longitudinal study. / 04.2015 / PubMed / Full text
  • Correlates and moderators of change in subjective memory and memory performance: findings from the health and retirement study. / 2015 / PubMed / Full text
  • Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging. / 2014 / PubMed / Full text
  • Resident health-related quality of life in Swiss nursing homes. / 07.2015 / PubMed / Full text
  • Multiple modes of assessment of gait are better than one to predict incident falls. / 05-06.2015 / PubMed / Full text
  • Social vulnerability and survival across levels of frailty in the Honolulu-Asia Aging Study. / 07.2015 / PubMed / Full text
  • Survival time of calves with positive BVD virus results born during the voluntary phase of the Irish eradication programme. / 01.05.2015 / PubMed / Full text
  • Physiological factors contributing to mobility loss over 9 years of follow-up—results from the InCHIANTI study. / 05.2015 / PubMed / Full text
  • Aspirin Has a Protective Effect Against Adverse Outcomes in Patients with Nonvariceal Upper Gastrointestinal Bleeding. / 07.2015 / PubMed / Full text
  • Spatial distribution of intracortical porosity varies across age and sex. / 06.2015 / PubMed / Full text
  • Older male physicians have lower risk of trochanteric but not cervical hip fractures. / 16.02.2015 / PubMed / Full text
  • Gender difference in diabetes-associated risk of first-ever and recurrent ischemic stroke. / 07.2015 / PubMed / Full text
  • Dose of jogging and long-term mortality: the Copenhagen City Heart Study. / 10.02.2015 / PubMed / Full text
  • Age-related differences in volumetric bone mineral density, microarchitecture, and bone strength of distal radius and tibia in Chinese women: a high-resolution pQCT reference database study. / 06.2015 / PubMed / Full text
  • Cardiac autonomic modulation in healthy elderly after different intensities of dynamic exercise. / 2015 / PubMed / Full text
  • Low-density lipoprotein cholesterol was inversely associated with 3-year all-cause mortality among Chinese oldest old: data from the Chinese Longitudinal Healthy Longevity Survey. / 03.2015 / PubMed / Full text
  • Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process. / 10.04.2015 / PubMed / Full text
  • Multimorbidity measures were poor predictors of adverse events in patients aged ≥80 years: a prospective cohort study. / 02.2015 / PubMed / Full text
  • Genetic relationship among reproductive traits in Nellore cattle. / 05.2015 / PubMed / Full text
  • Age-related differences when walking downhill on different sloped terrains. / 01.2015 / PubMed / Full text
  • HIV and aging: insights from the Asia Pacific HIV Observational Database (APHOD). / 03.2015 / PubMed / Full text
  • Obesity in the Context of Aging: Quality of Life Considerations. / 07.2015 / PubMed / Full text
  • Objective measures of activity level and mortality in older men. / 11.2014 / PubMed / Full text
  • The ROVIGO study (risk of vascular complications: impact of genetics in old people): protocol, study design, and preliminary results of the initial survey : cardiovascular epidemiology in the elderly. / 03.2015 / PubMed / Full text
  • Association between sleep duration and mortality is mediated by markers of inflammation and health in older adults: the Health, Aging and Body Composition Study. / 01.02.2015 / PubMed / Full text
  • Sarcopenia-related parameters and incident disability in older persons: results from the "invecchiare in Chianti" study. / 04.2015 / PubMed / Full text
  • Predicted maximal heart rate for upper body exercise testing. / 03.2016 / PubMed / Full text
  • Early life body mass trajectories and mortality in older age: findings from the Helsinki Birth Cohort Study. / 02.2015 / PubMed / Full text
  • Patient age and the prognosis of idiopathic membranous nephropathy. / 2014 / PubMed / Full text
  • Gender differences in survival in old age. / 12.2014 / PubMed / Full text
  • Long-term physical activity and risk of age-related cataract: a population-based prospective study of male and female cohorts. / 02.2015 / PubMed / Full text
  • Effects of body mass index, abdominal obesity, and type 2 diabetes on mortality in community-dwelling elderly in Sao Paulo, Brazil: analysis of prospective data from the SABE study. / 04.2015 / PubMed / Full text
  • All-cause and disease-specific mortality among male, former elite athletes: an average 50-year follow-up. / 07.2015 / PubMed / Full text
  • Characterization of metabolites determined by means of 1H HR MAS NMR in intervertebral disc degeneration. / 04.2015 / PubMed / Full text
  • The role of RecQ helicases in non-homologous end-joining. / 11-12.2014 / PubMed / Full text
  • Normal pediatric data for isovolumic acceleration at the lateral tricuspid valve annulus-a heart rate - dependent measure of right ventricular contractility. / 03.2015 / PubMed / Full text
  • Higher orthostatic heart rate predicts mortality: The Irish Longitudinal Study on Ageing (TILDA). / 04.2015 / PubMed / Full text
  • Aging and CaMKII alter intracellular Ca2 transients and heart rhythm in Drosophila melanogaster. / 2014 / PubMed / Full text
  • Do hassles mediate between life events and mortality in older men? Longitudinal findings from the VA Normative Aging Study. / 11.2014 / PubMed / Full text
  • Survival analysis of breast cancer subtypes in patients with spinal metastases. / 01.09.2014 / PubMed / Full text
  • Optimal management of colorectal liver metastases in older patients: a decision analysis. / 11.2014 / PubMed / Full text
  • Examining physiological responses across different driving maneuvers during an on-road driving task: a pilot study comparing older and younger drivers. / 2015 / PubMed / Full text
  • Rosa26-GFP direct repeat (RaDR-GFP) mice reveal tissue- and age-dependence of homologous recombination in mammals in vivo. / 06.2014 / PubMed / Full text
  • Association of total adiposity and computed tomographic measures of regional adiposity with incident cancer risk: a prospective population-based study of older adults. / 06.2014 / PubMed / Full text
  • Racial disparities in an aging population: the relationship between age and race in the management of African American men with high-risk prostate cancer. / 01.10.2014 / PubMed / Full text
  • Life expectancy following orbital exenteration. / 01.2015 / PubMed / Full text
  • Do age-disparate relationships drive HIV incidence in young women? Evidence from a population cohort in rural KwaZulu-Natal, South Africa. / 01.08.2014 / PubMed / Full text
  • Hippocampus and amygdala volumes in children and young adults at high-risk of schizophrenia: research synthesis. / 06.2014 / PubMed / Full text
  • Assessment of physical strain in younger and older subjects using heart rate and scalings of perceived exertion. / 2014 / PubMed / Full text
  • Episodic ozone exposure in adult and senescent Brown Norway rats: acute and delayed effect on heart rate, core temperature and motor activity. / 06.2014 / PubMed / Full text
  • Characterizing microarchitectural changes at the distal radius and tibia in postmenopausal women using HR-pQCT. / 08.2014 / PubMed / Full text
  • Individual and spousal education, mortality and life expectancy in Switzerland: a national cohort study. / 09.2014 / PubMed / Full text
  • Association Between 6-Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease. / 06.2014 / PubMed / Full text
  • Sleep duration and incidence of lung cancer in ageing men. / 31.03.2014 / PubMed / Full text
  • Effect of aging on carotid baroreflex control of blood pressure and leg vascular conductance in women. / 15.05.2014 / PubMed / Full text
  • Physical activity in older men: longitudinal associations with inflammatory and hemostatic biomarkers, N-terminal pro-brain natriuretic peptide, and onset of coronary heart disease and mortality. / 04.2014 / PubMed / Full text
  • Predicting all-cause and cause-specific mortality by static and dynamic measurements of allostatic load: a 10-year population-based cohort study in Taiwan. / 07.2014 / PubMed / Full text
  • Contribution of Alzheimer disease to mortality in the United States. / 25.03.2014 / PubMed / Full text
  • Physiological characteristics of an aging Olympic athlete. / 11.2014 / PubMed / Full text
  • Association of sex hormones, aging, and atrial fibrillation in men: the Framingham Heart Study. / 04.2014 / PubMed / Full text
  • A pooled analysis of waist circumference and mortality in 650,000 adults. / 03.2014 / PubMed / Full text
  • Hearing loss may be a non-motor feature of Parkinson's disease in older people in Taiwan. / 05.2014 / PubMed / Full text
  • Cognitive performance and functional status are the major factors predicting survival of centenarians in Poland. / 10.2014 / PubMed / Full text
  • Vitamin D deficiency in elderly people in Swedish nursing homes is associated with increased mortality. / 05.2014 / PubMed / Full text
  • Association between sex steroid levels and bone microarchitecture in men: the STRAMBO study. / 04.2014 / PubMed / Full text
  • Metabolomics signature improves the prediction of cardiovascular events in elderly subjects. / 02.2014 / PubMed / Full text
  • Mortality in systemic sclerosis: lessons learned from population-based and observational cohort studies. / 03.2014 / PubMed / Full text
  • BMI and all-cause mortality in older adults: a meta-analysis. / 04.2014 / PubMed / Full text
  • Gender-specific associations between physical functioning, bone quality, and fracture risk in older people. / 05.2014 / PubMed / Full text
  • Late-onset hypogonadism and mortality in aging men. / 04.2014 / PubMed / Full text
  • Effect of light-dark changes on the locomotor activity in open field in adult rats and opossums. / 11.2013 / PubMed / Full text
  • Differential contribution of afferent and central pathways to the development of baroreflex dysfunction in chronic kidney disease. / 04.2014 / PubMed / Full text
  • Association of 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D and parathyroid hormone with mortality among middle-aged and older European men. / 07.2014 / PubMed / Full text
  • Physiological response to a breed evaluation field test in Icelandic horses. / 03.2014 / PubMed / Full text

SIRT1[править]

  • Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats. / 03.12.2020 / PubMed / Full text
  • Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective. / 05.12.2020 / PubMed / Full text
  • Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells. / 10.2020 / PubMed / Full text
  • SIRT1 Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence. / 04.11.2020 / PubMed / Full text
  • Histone Deacetylase SIRT1, Smooth Muscle Cell Function, and Vascular Diseases. / 2020 / PubMed / Full text
  • 6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing SIRT1 and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation. / 27.10.2020 / PubMed / Full text
  • Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through SIRT1 activation and AKT/mTOR pathway inhibition. / 30.09.2020 / PubMed / Full text
  • SIRT1 Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence. / 2020 / PubMed / Full text
  • The Role of Sirtuins in Kidney Diseases. / 12.09.2020 / PubMed / Full text
  • The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. / 11.2020 / PubMed / Full text
  • Virus-Induced Asthma Exacerbations: SIRT1 Targeted Approach. / 13.08.2020 / PubMed / Full text
  • Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts. / 12.2020 / PubMed / Full text
  • Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/SIRT1-FOXA3-Beclin1 pathway. / 01.10.2020 / PubMed / Full text
  • Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence. / 08.2020 / PubMed / Full text
  • Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of SIRT1 in Human Dermal Fibroblasts. / 01.07.2020 / PubMed / Full text
  • SRT1720-induced activation of SIRT1 alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485. / 07.2020 / PubMed / Full text
  • miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss. / 2020 / PubMed / Full text
  • Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes. / 01-12.2020 / PubMed / Full text
  • Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats. / 10.2020 / PubMed / Full text
  • The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis. / 2020 / PubMed / Full text
  • Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells. / 2020 / PubMed / Full text
  • Spatiotemporal gating of SIRT1 functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia. / 24.03.2020 / PubMed / Full text
  • Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of SIRT1. / 2020 / PubMed / Full text
  • SIRT1 and aging related signaling pathways. / 04.2020 / PubMed / Full text
  • Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of SIRT1 signaling. / 01.05.2020 / PubMed / Full text
  • Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. / 04.2020 / PubMed / Full text
  • Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells. / 01.05.2020 / PubMed / Full text
  • Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal SIRT1 Levels Improving Cognition in Aged Rats. / 26.01.2020 / PubMed / Full text
  • Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating SIRT1. / 01.2020 / PubMed / Full text
  • Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence. / 06-07.2020 / PubMed / Full text
  • Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1. / 23.12.2019 / PubMed / Full text
  • The protective role of omentin-1 in IL-1β-induced chondrocyte senescence. / 12.2020 / PubMed / Full text
  • The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD Level Is Lower than the Sirtuin-Saturating Concentrations. / 24.12.2019 / PubMed / Full text
  • Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells. / 06.2020 / PubMed / Full text
  • Central nervous system SIRT1 expression is required for cued and contextual fear conditioning memory responses in aging mice. / 23.09.2019 / PubMed / Full text
  • Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education. / 10.2019 / PubMed
  • CO ameliorates endothelial senescence induced by 5-fluorouracil through SIRT1 activation. / 30.11.2019 / PubMed / Full text
  • Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating SIRT1 expression. / 20.10.2019 / PubMed / Full text
  • The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging. / 2019 / PubMed / Full text
  • Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. / 03.2020 / PubMed / Full text
  • Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure. / 13.02.2020 / PubMed / Full text
  • Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of SIRT1. / 2019 / PubMed / Full text
  • Activation of the miR-34a-Mediated SIRT1/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice. / 10.2019 / PubMed / Full text
  • [Ginsenoside Rg_1 induces leukemia stem cell senescence via SIRT1/TSC_2 signal axis]. / 06.2019 / PubMed / Full text
  • miR-23b-3p regulates apoptosis and autophagy via suppressing SIRT1 in lens epithelial cells. / 12.2019 / PubMed / Full text
  • Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
  • Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. / 08.2019 / PubMed / Full text
  • Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence. / 01.10.2019 / PubMed / Full text
  • Involvement of [i]microRNA-34a[/i] in Age-Related Susceptibility to Oxidative Stress in ARPE-19 Cells by Targeting the Silent Mating Type Information Regulation 2 Homolog 1/p66shc Pathway: Implications for Age-Related Macular Degeneration. / 2019 / PubMed / Full text
  • GPR39 agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence. / 12.2019 / PubMed / Full text
  • Rational design of novel sirtuin 1 activators via structure-activity insights from application of QSAR modeling. / 2019 / PubMed / Full text
  • Metformin prevents murine ovarian aging. / 10.06.2019 / PubMed / Full text
  • Time-restricted feeding delays the emergence of the age-associated, neoplastic-prone tissue landscape. / 12.06.2019 / PubMed / Full text
  • Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway. / 10.06.2019 / PubMed / Full text
  • SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy. / 08.2019 / PubMed / Full text
  • Transcriptome analysis revealed potential mechanisms of differences in physiological stress responses between caged male and female magpies. / 03.06.2019 / PubMed / Full text
  • Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. / 10.2019 / PubMed / Full text
  • Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models. / 02.2019 / PubMed / Full text
  • Molecular and Cellular Characterization of SIRT1 Allosteric Activators. / 2019 / PubMed / Full text
  • Total flavonoids from the Carya cathayensis Sarg. leaves inhibit HUVEC senescence through the miR-34a/SIRT1 pathway. / 10.2019 / PubMed / Full text
  • Impaired SIRT1 activity leads to diminution in glomerular endowment without accelerating age-associated GFR decline. / 05.2019 / PubMed / Full text
  • Estrogen-SIRT1 Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis. / 01.01.2020 / PubMed / Full text
  • Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri. / 09.2019 / PubMed / Full text
  • Protective effect of vildagliptin on TNF-α-induced chondrocyte senescence. / 07.2019 / PubMed / Full text
  • Polymorphism rs7895833 in the SIRT1 gene and its association with dyslipidaemia in the elderly. / 07-08.2019 / PubMed / Full text
  • Modulation of miR-34a/SIRT1 signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis. / 07.2019 / PubMed / Full text
  • Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow. / 18.04.2019 / PubMed / Full text
  • Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom [i]Cordyceps militaris[/i] Linn., Ameliorates Age-Related Testicular Dysfunction in Rats. / 23.04.2019 / PubMed / Full text
  • The resistant effect of SIRT1 in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway. / 31.05.2019 / PubMed / Full text
  • Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. / 2019 / PubMed / Full text
  • The role of SIRT1 in neuroinflammation and cognitive dysfunction in aged rats after anesthesia and surgery. / 2019 / PubMed / Full text
  • NAD supplementation rejuvenates aged gut adult stem cells. / 06.2019 / PubMed / Full text
  • NMNAT2-mediated NAD generation is essential for quality control of aged oocytes. / 06.2019 / PubMed / Full text
  • Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure. / 07.2019 / PubMed / Full text
  • Drugs targeting SIRT1, a new generation of therapeutics for osteoporosis and other bone related disorders? / 05.2019 / PubMed / Full text
  • Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks. / 11.03.2019 / PubMed / Full text
  • Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions. / 04.2019 / PubMed / Full text
  • Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson's disease. / 04.02.2019 / PubMed / Full text
  • Bone Marrow Mesenchymal Stem Cells-Derived Exosomal MiR-29b-3p Regulates Aging-Associated Insulin Resistance. / 26.02.2019 / PubMed / Full text
  • Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats. / 02.2019 / PubMed / Full text
  • Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease. / 05.2019 / PubMed / Full text
  • Generation of a novel model of primary human cell senescence through Tenovin-6 mediated inhibition of sirtuins. / 06.2019 / PubMed / Full text
  • Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. / 04.2019 / PubMed / Full text
  • Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. / 23.01.2019 / PubMed / Full text
  • Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation. / 2018 / PubMed / Full text
  • NKT-like cells reveal higher than T lymphocytes expression of cellular protective proteins HSP70 and SOD2 and comparably increased expression of SIRT1 in the oldest seniors. / 2018 / PubMed / Full text
  • Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway. / 04.2019 / PubMed / Full text
  • Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats. / 23.12.2018 / PubMed / Full text
  • Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation. / 2018 / PubMed / Full text
  • Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice. / 15.04.2019 / PubMed / Full text
  • CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2. / 2018 / PubMed / Full text
  • Amentoflavone Induces Autophagy and Modulates p53. / 04.2019 / PubMed / Full text
  • Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells. / 03.2019 / PubMed / Full text
  • Sirtuins: Developing Innovative Treatments for Aged-Related Memory Loss and Alzheimer's Disease. / 2018 / PubMed / Full text
  • N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation. / 01.2019 / PubMed / Full text
  • Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice. / 20.11.2018 / PubMed / Full text
  • Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation. / 2018 / PubMed / Full text
  • Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and [i]C. elegans[/i]. / 20.11.2018 / PubMed / Full text
  • Sirtuins and NAD in the Development and Treatment of Metabolic and Cardiovascular Diseases. / 14.09.2018 / PubMed / Full text
  • SIRT1 deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis. / 12.2018 / PubMed / Full text
  • Prevention of Senescence in Vasculature Through Quiescence. / 10.2018 / PubMed / Full text
  • Melatonin and inflammation-Story of a double-edged blade. / 11.2018 / PubMed / Full text
  • ALDH2 mediates the dose-response protection of chronic ethanol against endothelial senescence through SIRT1/p53 pathway. / 12.10.2018 / PubMed / Full text
  • Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats. / 08.2018 / PubMed / Full text
  • Endothelial SIRT1 prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells. / 01.03.2019 / PubMed / Full text
  • Effects of Ginsenoside Rg3 on fatigue resistance and SIRT1 in aged rats. / 01.11.2018 / PubMed / Full text
  • PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD levels and increasing SIRT1 activity. / 23.08.2018 / PubMed / Full text
  • Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing SIRT1 and SIRT3 expression. / 10.2018 / PubMed / Full text
  • Liver regeneration in aged mice: new insights. / 28.08.2018 / PubMed / Full text
  • Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit's Heart and Liver. / 2018 / PubMed / Full text
  • Defect of SIRT1-FoxO3a axis is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated cellular senescence and nematode aging. / 04.2019 / PubMed / Full text
  • Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls. / 10.2018 / PubMed / Full text
  • Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes. / 01.05.2019 / PubMed / Full text
  • PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis. / 07.08.2018 / PubMed / Full text
  • Effect of oral appliance on circulating leukocyte telomere length and SIRT1 in obstructive sleep apnea. / 03.2019 / PubMed / Full text
  • miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating SIRT1 (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase). / 09.2018 / PubMed / Full text
  • A SIRT1-centered circuitry regulates breast cancer stemness and metastasis. / 12.2018 / PubMed / Full text
  • Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/SIRT1 signaling pathway. / 06.2018 / PubMed / Full text
  • Sirtuin 1 and Alzheimer's disease: An up-to-date review. / 10.2018 / PubMed / Full text
  • CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans. / 10.2018 / PubMed / Full text
  • Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-SIRT1-eNOS pathway. / 09.2018 / PubMed / Full text
  • Serum containing Buyang Huanwu decoction prevents age-associated migration and invasion of human vascular smooth muscle cells by up regulating SIRT1 expression. / 17.07.2018 / PubMed / Full text
  • Role of accelerated aging in limb muscle wasting of patients with COPD. / 2018 / PubMed / Full text
  • Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells. / 15.09.2018 / PubMed / Full text
  • Mesenchymal stem cells confer resistance to doxorubicin-induced cardiac senescence by inhibiting microRNA-34a. / 06.2018 / PubMed / Full text
  • The circadian clock in adult neural stem cell maintenance. / 02.2019 / PubMed / Full text
  • Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri. / 09.2018 / PubMed / Full text
  • Loss of NAMPT in aging retinal pigment epithelium reduces NAD availability and promotes cellular senescence. / 12.06.2018 / PubMed / Full text
  • Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes. / 06.2018 / PubMed / Full text
  • SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease. / 31.05.2018 / PubMed / Full text
  • Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence. / 09.2018 / PubMed / Full text
  • Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial Function. / 09.2018 / PubMed / Full text
  • Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats. / 2018 / PubMed / Full text
  • SIRT1 reverses senescence via enhancing autophagy and attenuates oxidative stress-induced apoptosis through promoting p53 degradation. / 01.10.2018 / PubMed / Full text
  • Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers. / 08.2018 / PubMed / Full text
  • Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition. / 07.2018 / PubMed / Full text
  • Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of SIRT1. / 2017 / PubMed / Full text
  • Role of hypothalamus in aging and its underlying cellular mechanisms. / 01.2019 / PubMed / Full text
  • The variable role of SIRT1 in the maintenance and differentiation of mesenchymal stem cells. / 04.2018 / PubMed / Full text
  • Sirtuins in Renal Health and Disease. / 07.2018 / PubMed / Full text
  • Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, SIRT1, SIRT3, and VEGF in the Substantia Nigra. / 10.11.2018 / PubMed / Full text
  • MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells. / 03.04.2018 / PubMed / Full text
  • Natural products with anti-aging potential: Affected targets and molecular mechanisms. / 01.11.2018 / PubMed / Full text
  • [Effect of microRNA-34a/SIRT1/p53 signal pathway on notoginsenoside R₁ delaying vascular endothelial cell senescence]. / 02.2018 / PubMed / Full text
  • SIRT1 and microRNAs: The role in breast, lung and prostate cancers. / 01.06.2018 / PubMed / Full text
  • Leukotriene D4 induces cellular senescence in osteoblasts. / 05.2018 / PubMed / Full text
  • Impairment of an Endothelial NAD -H S Signaling Network Is a Reversible Cause of Vascular Aging. / 22.03.2018 / PubMed / Full text
  • Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas. / 08.2018 / PubMed / Full text
  • Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. / 06.03.2018 / PubMed / Full text
  • Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming. / 05.2018 / PubMed / Full text
  • HGF and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the SIRT1/FOXO1 Signaling Pathway. / 2018 / PubMed / Full text
  • The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system. / 03.2018 / PubMed / Full text
  • Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. / 04.2018 / PubMed / Full text
  • Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes. / 03.2018 / PubMed / Full text
  • Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress. / 20.02.2018 / PubMed / Full text
  • Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury. / 11.01.2018 / PubMed / Full text
  • Acetylshikonin from Zicao attenuates cognitive impairment and hippocampus senescence in d-galactose-induced aging mouse model via upregulating the expression of SIRT1. / 03.2018 / PubMed / Full text
  • Dexamethasone downregulates SIRT1 and IL6 and upregulates EDN1 genes in stem cells derived from gingivae via the AGE/RAGE pathway. / 03.2018 / PubMed / Full text
  • Sirtuins in Brain Aging and Neurological Disorders. / 2017 / PubMed / Full text
  • [Aging-related change of erectile function and the expression of SIRT1]. / 12.2016 / PubMed
  • Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans. / 2017 / PubMed / Full text
  • Maternal aging affects oocyte resilience to carbonyl cyanide-m-chlorophenylhydrazone -induced mitochondrial dysfunction in cows. / 2017 / PubMed / Full text
  • Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating SIRT1 activity and antioxidant gene expression in mouse cells. / 12.2017 / PubMed / Full text
  • Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™). / 04.2018 / PubMed / Full text
  • Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through SIRT1. / 2017 / PubMed / Full text
  • Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating SIRT1-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation. / 14.11.2017 / PubMed / Full text
  • Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice. / 13.10.2017 / PubMed / Full text
  • O-GlcNAcylation of SIRT1 enhances its deacetylase activity and promotes cytoprotection under stress. / 14.11.2017 / PubMed / Full text
  • Aging as an Epigenetic Phenomenon. / 10.2017 / PubMed / Full text
  • MeCP2 mediated dysfunction in senescent EPCs. / 03.10.2017 / PubMed / Full text
  • Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. / 01.2018 / PubMed / Full text
  • A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction. / 12.09.2017 / PubMed / Full text
  • Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence. / 17.10.2017 / PubMed / Full text
  • Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts. / 28.12.2017 / PubMed / Full text
  • Blocking SIRT1 inhibits cell proliferation and promotes aging through the PI3K/AKT pathway. / 01.12.2017 / PubMed / Full text
  • SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis. / 2017 / PubMed / Full text
  • [Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell]. / 02.2017 / PubMed / Full text
  • SIRT1 is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity. / 05.02.2018 / PubMed / Full text
  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
  • The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway. / 11.2017 / PubMed / Full text
  • Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats. / 03.2018 / PubMed / Full text
  • Aquatide Activation of SIRT1 Reduces Cellular Senescence through a SIRT1-FOXO1-Autophagy Axis. / 01.09.2017 / PubMed / Full text
  • Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3. / 20.10.2017 / PubMed / Full text
  • Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging. / 10.08.2017 / PubMed / Full text
  • High glucose and free fatty acids induce endothelial progenitor cell senescence via PGC-1α/SIRT1 signaling pathway. / 10.2017 / PubMed / Full text
  • Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. / 2017 / PubMed / Full text
  • Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway. / 01.2018 / PubMed / Full text
  • Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression. / 2017 / PubMed / Full text
  • Inflammation, Stem Cells, and the Aging Hypothalamus. / 08.2017 / PubMed / Full text
  • Myricetin improves endurance capacity and mitochondrial density by activating SIRT1 and PGC-1α. / 24.07.2017 / PubMed / Full text
  • Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer. / 2017 / PubMed / Full text
  • The emerging role of alternative splicing in senescence and aging. / 10.2017 / PubMed / Full text
  • miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans. / 08.2017 / PubMed / Full text
  • Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells. / 01.2018 / PubMed / Full text
  • SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection. / 10.03.2018 / PubMed / Full text
  • Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging. / 30.01.2018 / PubMed / Full text
  • Reduction in podocyte SIRT1 accelerates kidney injury in aging mice. / 01.09.2017 / PubMed / Full text
  • Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs. / 12.06.2017 / PubMed / Full text
  • Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers. / 2018 / PubMed / Full text
  • The NAD /PARP1/SIRT1 Axis in Aging. / 06.2017 / PubMed / Full text
  • Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota. / 09.2017 / PubMed / Full text
  • Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-SIRT1 pathway. / 08.2017 / PubMed / Full text
  • Bushen-Yizhi formula ameliorates cognitive dysfunction through SIRT1/ER stress pathway in SAMP8 mice. / 25.07.2017 / PubMed / Full text
  • Caveolin-1 deficiency induces premature senescence with mitochondrial dysfunction. / 08.2017 / PubMed / Full text
  • Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-FOXO1 pathway. / 2017 / PubMed / Full text
  • Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing. / 02.2018 / PubMed / Full text
  • Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats. / 08.2017 / PubMed / Full text
  • Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment. / 30.05.2017 / PubMed / Full text
  • During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent. / 08.2017 / PubMed / Full text
  • Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. / 01.06.2017 / PubMed / Full text
  • Regulation of stem cell aging by SIRT1 - Linking metabolic signaling to epigenetic modifications. / 05.11.2017 / PubMed / Full text
  • Ampelopsin attenuates the atrophy of skeletal muscle from d-gal-induced aging rats through activating AMPK/SIRT1/PGC-1α signaling cascade. / 06.2017 / PubMed / Full text
  • SIRT1 Polymorphisms and Serum-Induced SIRT1 Protein Expression in Aging and Frailty: The CHAMP Study. / 01.07.2017 / PubMed / Full text
  • Melatonin reverses H O -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB. / 08.2017 / PubMed / Full text
  • Alkylresorcinols activate SIRT1 and delay ageing in Drosophila melanogaster. / 02.03.2017 / PubMed / Full text
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