Aging genes 100

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  • Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe mice: role of SIRT1. / 18.11.2020 / PubMed / Full text
  • Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism. / 06.11.2020 / PubMed / Full text
  • Anti-aging effect of DL-β-hydroxybutyrate against hepatic cellular senescence induced by D-galactose or γ-irradiation via autophagic flux stimulation in male rats. / 01-02.2021 / PubMed / Full text
  • Exploring the extensive crosstalk between the antagonistic cytokines- TGF-β and TNF-α in regulating cancer pathogenesis. / 03.11.2020 / PubMed / Full text
  • Long non-coding RNA SNHG29 regulates cell senescence via p53/p21 signaling in spontaneous preterm birth. / 15.10.2020 / PubMed / Full text
  • Cognition Is Associated With Peripheral Immune Molecules in Healthy Older Adults: A Cross-Sectional Study. / 2020 / PubMed / Full text
  • Anti-aging effects of [i]Ribes meyeri[/i] anthocyanins on neural stem cells and aging mice. / 12.09.2020 / PubMed / Full text
  • Effects of a four week detraining period on physical, metabolic, and inflammatory profiles of elderly women who regularly participate in a program of strength training. / 2020 / PubMed / Full text
  • Contribution of Porphyromonas gingivalis lipopolysaccharide to experimental periodontitis in relation to aging. / 26.08.2020 / PubMed / Full text
  • New MoDC-Targeting TNF Fusion Proteins Enhance Cyclic Di-GMP Vaccine Adjuvanticity in Middle-Aged and Aged Mice. / 2020 / PubMed / Full text
  • Cognitive impairment in elderly patients with rheumatic disease and the effect of disease-modifying anti-rheumatic drugs. / 30.08.2020 / PubMed / Full text
  • Cotinine ameliorates memory and learning impairment in senescent mice. / 11.2020 / PubMed / Full text
  • Kynurenines link chronic inflammation to functional decline and physical frailty. / 20.08.2020 / PubMed / Full text
  • Voluntary exercise training attenuated the middle-aged maturity-induced cardiac apoptosis. / 15.10.2020 / PubMed / Full text
  • Preclinical Evaluation of a Food-Derived Functional Ingredient to Address Skeletal Muscle Atrophy. / 29.07.2020 / PubMed / Full text
  • Childhood survivors of high-risk neuroblastoma show signs of immune recovery and not immunosenescence. / 12.2020 / PubMed / Full text
  • FK506 induces lung lymphatic endothelial cell senescence and downregulates LYVE-1 expression, with associated decreased hyaluronan uptake. / 31.07.2020 / PubMed / Full text
  • Late-onset hypogonadism: Reductio ad absurdum of the cardiovascular risk-benefit of testosterone replacement therapy. / 11.2020 / PubMed / Full text
  • Doxorubicin generates senescent microglia that exhibit altered proteomes, higher levels of cytokine secretion, and a decreased ability to internalize amyloid β. / 15.10.2020 / PubMed / Full text
  • Time restricted feeding provides a viable alternative to alternate day fasting when evaluated in terms of redox homeostasis in rats. / 16.07.2020 / PubMed / Full text
  • Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy. / 2020 / PubMed / Full text
  • Chrysin Impact on Oxidative and Inflammation Damages in the Liver of Aged Male Rats. / 17.07.2020 / PubMed / Full text
  • Correction of immunosuppression in aged septic rats by human ghrelin and growth hormone through the vagus nerve-dependent inhibition of TGF-β production. / 16.07.2020 / PubMed / Full text
  • Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients. / 10.2020 / PubMed / Full text
  • [i]Andrographis paniculata[/i] and Its Bioactive Diterpenoids Against Inflammation and Oxidative Stress in Keratinocytes. / 17.06.2020 / PubMed / Full text
  • Etanercept improves aging-induced cognitive deficits by reducing inflammation and vascular dysfunction in rats. / 01.10.2020 / PubMed / Full text
  • Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients. / 09.2020 / PubMed / Full text
  • Bone marrow mesenchymal stem cells improve thymus and spleen function of aging rats through affecting P21/PCNA and suppressing oxidative stress. / 19.06.2020 / PubMed / Full text
  • Glycolic acid adjusted to pH 4 stimulates collagen production and epidermal renewal without affecting levels of proinflammatory TNF-alpha in human skin explants. / 24.06.2020 / PubMed / Full text
  • A20 of nucleus pulposus cells plays a self-protection role via the nuclear factor-kappa B pathway in the inflammatory microenvironment. / 05.2020 / PubMed / Full text
  • Age-associated decline in neural, endocrine, and immune responses in men and women: Involvement of intracellular signaling pathways. / 15.08.2020 / PubMed / Full text
  • Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults. / 2020 / PubMed / Full text
  • Activation of FoxO1/SIRT1/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis. / 12.06.2020 / PubMed / Full text
  • The senescence-associated secretome as an indicator of age and medical risk. / 18.06.2020 / PubMed / Full text
  • Exercise Partially Rejuvenates Muscle Stem Cells. / 06.2020 / PubMed / Full text
  • Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress. / 08.2020 / PubMed / Full text
  • Potential therapeutic effects of endothelial cells trans-differentiated from Wharton's Jelly-derived mesenchymal stem cells on altered vascular functions in aged diabetic rat model. / 2020 / PubMed / Full text
  • [Effect of fragmented sleep on postoperative cognitive function and central neuroinflammation]. / 05.05.2020 / PubMed / Full text
  • Can blocking inflammation enhance immunity during aging? / 05.2020 / PubMed / Full text
  • [FAS- and TNF-dependent ways participation in apoptosis mechanisms in hypotalumus in physiological and pathological aging.] / 2020 / PubMed
  • Ultrasound-guided continuous thoracic paravertebral block alleviates postoperative delirium in elderly patients undergoing esophagectomy: A randomized controlled trial. / 04.2020 / PubMed / Full text
  • 17β-Estradiol improves insulin signalling and insulin resistance in the aged female hearts: Role of inflammatory and anti-inflammatory cytokines. / 15.07.2020 / PubMed / Full text
  • Synergistic Antitumor Efficacy of Magnetohyperthermia and Poly(lactic-co-glycolic acid)-Encapsulated Selol in Ehrlich Breast Adenocarcinoma Treatment in Elderly Swiss Mice. / 01.02.2020 / PubMed / Full text
  • Pinitol suppresses TNF-α-induced chondrocyte senescence. / 19.03.2020 / PubMed / Full text
  • [Aging of skin fibroblasts: genetic and epigenetic factors.] / 2019 / PubMed
  • Functional and traditional training improve muscle power and reduce proinflammatory cytokines in older women: A randomized controlled trial. / 01.07.2020 / PubMed / Full text
  • Associations of TNF-α -308 G>A and TNF-β 252 A>G with Physical Function and BNP-Rugao Longevity and Ageing Study. / 2020 / PubMed / Full text
  • 3D TECA hydrogel reduces cellular senescence and enhances fibroblasts migration in wound healing. / 07.2018 / PubMed / Full text
  • Regulatory Effect of Anwulignan on the Immune Function Through Its Antioxidation and Anti-Apoptosis in D-Galactose-Induced Aging Mice. / 2020 / PubMed / Full text
  • Pretreatment Frailty Is Independently Associated With Increased Risk of Infections After Immunosuppression in Patients With Inflammatory Bowel Diseases. / 06.2020 / PubMed / Full text
  • The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1. / 2020 / PubMed / Full text
  • In the Absence of a TCR Signal IL-2/IL-12/18-Stimulated γδ T Cells Demonstrate Potent Anti-Tumoral Function Through Direct Killing and Senescence Induction in Cancer Cells. / 04.01.2020 / PubMed / Full text
  • Aging is associated with loss of beneficial effects of estrogen on leptin responsiveness in mice fed high fat diet: Role of estrogen receptor α and cytokines. / 03.2020 / PubMed / Full text
  • Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease? / 2019 / PubMed / Full text
  • Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents. / 01.02.2020 / PubMed / Full text
  • Oral Administration of Okara Soybean By-Product Attenuates Cognitive Impairment in a Mouse Model of Accelerated Aging. / 03.12.2019 / PubMed / Full text
  • Electric vagal nerve stimulation inhibits inflammation and improves early postoperation cognitive dysfunction in aged rats. / 23.11.2019 / PubMed / Full text
  • Metformin decreases LPS-induced inflammatory response in rabbit annulus fibrosus stem/progenitor cells by blocking HMGB1 release. / 26.11.2019 / PubMed / Full text
  • The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro. / 11.12.2019 / PubMed / Full text
  • Arsenic induces human chondrocyte senescence and accelerates rat articular cartilage aging. / 01.2020 / PubMed / Full text
  • Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content. / 08.11.2019 / PubMed / Full text
  • Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161-expressing cells. / 12.2019 / PubMed / Full text
  • Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians. / 26.11.2019 / PubMed / Full text
  • Gut microbiota combined with metabolomics reveals the metabolic profile of the normal aging process and the anti-aging effect of FuFang Zhenshu TiaoZhi(FTZ) in mice. / 01.2020 / PubMed / Full text
  • Intervertebral disc ageing and degeneration: The antiapoptotic effect of oestrogen. / 01.2020 / PubMed / Full text
  • MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages. / 30.01.2020 / PubMed / Full text
  • Aerobic exercise modulates cytokine profile and sleep quality in elderly. / 06.2019 / PubMed / Full text
  • Trehalose targets Nrf2 signal to alleviate d-galactose induced aging and improve behavioral ability. / 01.01.2020 / PubMed / Full text
  • Anti-Inflammatory and Anti-Aging Evaluation of Pigment-Protein Complex Extracted from [i]Chlorella Pyrenoidosa[/i]. / 16.10.2019 / PubMed / Full text
  • Inflammatory mediators and the risk of falls among older women with acute low back pain: data from Back Complaints in the Elders (BACE)-Brazil. / 03.2020 / PubMed / Full text
  • Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders. / 03.10.2019 / PubMed / Full text
  • Study on Metabolic Trajectory of Liver Aging and the Effect of Fufang Zhenzhu Tiaozhi on Aging Mice. / 2019 / PubMed / Full text
  • Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults. / 13.07.2020 / PubMed / Full text
  • Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia. / 14.09.2019 / PubMed / Full text
  • Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice. / 14.08.2019 / PubMed / Full text
  • Moderate hyperoxia induces senescence in developing human lung fibroblasts. / 01.11.2019 / PubMed / Full text
  • Aging-related carcinoembryonic antigen-related cell adhesion molecule 1 signaling promotes vascular dysfunction. / 12.2019 / PubMed / Full text
  • Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APP /PS1 Transgenic Mice. / 2019 / PubMed / Full text
  • Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. / 09.2019 / PubMed / Full text
  • Knockout of longevity gene Sirt1 in zebrafish leads to oxidative injury, chronic inflammation, and reduced life span. / 2019 / PubMed / Full text
  • Glycation of macrophages induces expression of pro-inflammatory cytokines and reduces phagocytic efficiency. / 29.07.2019 / PubMed / Full text
  • Tamoxifen-induced, intestinal-specific deletion of [i]Slc5a6[/i] in adult mice leads to spontaneous inflammation: involvement of NF-κB, NLRP3, and gut microbiota. / 01.10.2019 / PubMed / Full text
  • Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. / 22.07.2019 / PubMed / Full text
  • Inflammatory markers and bone health in postmenopausal women: a cross-sectional overview. / 2019 / PubMed / Full text
  • TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. / 29.08.2019 / PubMed / Full text
  • Plasma Cells Are Obligate Effectors of Enhanced Myelopoiesis in Aging Bone Marrow. / 20.08.2019 / PubMed / Full text
  • Aging-induced elevation in circulating complement C1q level is associated with arterial stiffness. / 09.2019 / PubMed / Full text
  • Immune Mechanisms Underlying Susceptibility to Endotoxin Shock in Aged Hosts: Implication in Age-Augmented Generalized Shwartzman Reaction. / 02.07.2019 / PubMed / Full text
  • Inflammation-related genes are associated with epigenetic aging in HIV. / 12.2019 / PubMed / Full text
  • Function, Oxidative, and Inflammatory Stress Parameters in Immune Cells as Predictive Markers of Lifespan throughout Aging. / 2019 / PubMed / Full text
  • The Impact of Prophylactic Lacosamide on LPS-Induced Neuroinflammation in Aged Rats. / 10.2019 / PubMed / Full text
  • Impaired sleep quality is associated with concurrent elevations in inflammatory markers: are post-menopausal women at greater risk? / 08.07.2019 / PubMed / Full text
  • Potential effects of rapeseed peptide Maillard reaction products on aging-related disorder attenuation and gut microbiota modulation in d-galactose induced aging mice. / 17.07.2019 / PubMed / Full text
  • Ellagic acid dose and time-dependently abrogates d-galactose-induced animal model of aging: Investigating the role of PPAR-γ. / 01.09.2019 / PubMed / Full text
  • Lactobacillus sp. improved microbiota and metabolite profiles of aging rats. / 08.2019 / PubMed / Full text
  • Local and systemic effects of aging on acute pancreatitis. / 07.2019 / PubMed / Full text
  • Salicin prevents TNF-α-induced cellular senescence in human umbilical vein endothelial cells (HUVECs). / 12.2019 / PubMed / Full text
  • Age-related dynamics of pro-inflammatory cytokines in equine bronchoalveolar lavage (BAL) fluid and peripheral blood from horses managed on pasture. / 09.2019 / PubMed / Full text
  • The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity. / 06.2019 / PubMed / Full text
  • The effects of vitamin-rich carbohydrate pretreatment on the surgical stress response and S-100β after splenectomy in elderly rats. / 15.05.2019 / PubMed / Full text
  • Stem Cell-Derived Exosomes Prevent Aging-Induced Cardiac Dysfunction through a Novel Exosome/lncRNA MALAT1/NF-[i]κ[/i]B/TNF-[i]α[/i] Signaling Pathway. / 2019 / PubMed / Full text
  • Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK. / 10.2019 / PubMed / Full text
  • Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet. / 09.2019 / PubMed / Full text
  • Age-related cytokine effects on cancer-related fatigue and quality of life in acute myeloid leukemia. / 04.2020 / PubMed / Full text
  • Protective effect of vildagliptin on TNF-α-induced chondrocyte senescence. / 07.2019 / PubMed / Full text
  • Platelet-Rich Plasma (PRP) From Older Males With Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation. / 08.2019 / PubMed / Full text
  • Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway. / 15.07.2019 / PubMed / Full text
  • Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway. / 07.2019 / PubMed / Full text
  • Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice. / 02.05.2019 / PubMed / Full text
  • Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. / 08.2019 / PubMed / Full text
  • Resveratrol attenuates inflammation environment-induced nucleus pulposus cell senescence [i]in vitro[/i]. / 31.05.2019 / PubMed / Full text
  • Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. / 2019 / PubMed / Full text
  • Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention. / 06.2019 / PubMed / Full text
  • 2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. / 01.04.2019 / PubMed / Full text
  • N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms. / 05.2019 / PubMed / Full text
  • Neuroprotective Effect of Dioscin on the Aging Brain. / 30.03.2019 / PubMed / Full text
  • CSF Cytokines in Aging, Multiple Sclerosis, and Dementia. / 2019 / PubMed / Full text
  • Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. / 07.2019 / PubMed / Full text
  • A double-blind, randomized trial on the effect of a broad-spectrum dietary supplement on key biomarkers of cellular aging including inflammation, oxidative stress, and DNA damage in healthy adults. / 04.01.2017 / PubMed / Full text
  • A New Understanding of the Role of IL-1 in Age-Related Intervertebral Disc Degeneration in a Murine Model. / 08.2019 / PubMed / Full text
  • Methane ameliorates post-operative cognitive dysfunction by inhibiting microglia NF-κB/MAPKs pathway and promoting IL-10 expression in aged mice. / 06.2019 / PubMed / Full text
  • Age-dependent hepatic alterations induced by a high-fat high-fructose diet. / 05.2019 / PubMed / Full text
  • The senescent status of endothelial cells affects proliferation, inflammatory profile and SOX2 expression in bone marrow-derived mesenchymal stem cells. / 06.2019 / PubMed / Full text
  • Reduced CXCL1/GRO chemokine plasma levels are a possible biomarker of elderly depression. / 15.04.2019 / PubMed / Full text
  • Nontuberculous mycobacterium M. avium infection predisposes aged mice to cardiac abnormalities and inflammation. / 06.2019 / PubMed / Full text
  • Epigenetic Age Acceleration in Adolescence Associates With BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease. / 01.07.2019 / PubMed / Full text
  • Converging Paths of Pulmonary Arterial Hypertension and Cellular Senescence. / 07.2019 / PubMed / Full text
  • Gender-specific association of body composition with inflammatory and adipose-related markers in healthy elderly Europeans from the NU-AGE study. / 09.2019 / PubMed / Full text
  • Lifelong aerobic exercise protects against inflammaging and cancer. / 2019 / PubMed / Full text
  • Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. / 06.2019 / PubMed / Full text
  • The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature. / 01.08.2019 / PubMed / Full text
  • Impact of simulated biological aging on physicochemical and biocompatibility properties of cyclic olefin copolymers. / 04.2019 / PubMed / Full text
  • Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation. / 2018 / PubMed / Full text
  • Lifelong exercise practice and immunosenescence: Master athletes cytokine response to acute exercise. / 03.2019 / PubMed / Full text
  • Human T2R38 Bitter Taste Receptor Expression in Resting and Activated Lymphocytes. / 2018 / PubMed / Full text
  • Ameliorative effect of supercritical fluid extract of Chrysanthemum indicum Linnén against D-galactose induced brain and liver injury in senescent mice via suppression of oxidative stress, inflammation and apoptosis. / 24.04.2019 / PubMed / Full text
  • [Effect of saponins extracted from Panax japonicas on inhibiting myocardial fibrosis by TGF-β1/Smad3 signaling pathway in aging rats]. / 11.2018 / PubMed / Full text
  • Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA DHA. / 06.2019 / PubMed / Full text
  • CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2. / 2018 / PubMed / Full text
  • Role of Exercise in Vascular Function and Inflammatory Profile in Age-Related Obesity. / 2018 / PubMed / Full text
  • Establishment of a lethal aged mouse model of human respiratory syncytial virus infection. / 01.2019 / PubMed / Full text
  • Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs. / 03.2019 / PubMed / Full text
  • Effect of Myricetin on Primary Open-angle Glaucoma. / 2018 / PubMed / Full text
  • Chronic rhinosinusitis in elderly patients is associated with an exaggerated neutrophilic proinflammatory response to pathogenic bacteria. / 03.2019 / PubMed / Full text
  • Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence. / 2018 / PubMed / Full text
  • Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. / 11.12.2018 / PubMed / Full text
  • Association of pro-inflammatory cytokines and monocyte subtypes in older and younger patients on clinical outcomes after mechanical circulatory support device implantation. / 02.2019 / PubMed / Full text
  • Adipose TSHB in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence. / 2018 / PubMed / Full text
  • Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. / 05.2019 / PubMed / Full text
  • Higher levels of tumor necrosis factor β are associated with frailty in socially vulnerable community-dwelling older adults. / 06.11.2018 / PubMed / Full text
  • Epigenetics of Delirium and Aging: Potential Role of DNA Methylation Change on Cytokine Genes in Glia and Blood Along With Aging. / 2018 / PubMed / Full text
  • Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats. / 11.2018 / PubMed / Full text
  • Ellagic acid reveals promising anti-aging effects against d-galactose-induced aging on human neuroblastoma cell line, SH-SY5Y: A mechanistic study. / 12.2018 / PubMed / Full text
  • The Neuro-Immuno-Senescence Integrative Model (NISIM) on the Negative Association Between Parasympathetic Activity and Cellular Senescence. / 2018 / PubMed / Full text
  • Human umbilical cord blood plasma alleviates age-related olfactory dysfunction by attenuating peripheral TNF-α expression. / 04.2019 / PubMed / Full text
  • Manipulating fenestrations in young and old liver sinusoidal endothelial cells. / 01.01.2019 / PubMed / Full text
  • The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease. / 10.2018 / PubMed / Full text
  • Myeloid cell-derived tumor necrosis factor-alpha promotes sarcopenia and regulates muscle cell fusion with aging muscle fibers. / 12.2018 / PubMed / Full text
  • mRNA expressions of peroxisome proliferator-activated receptor gamma coactivator 1α, tumor necrosis factor-α, and interleukin-6 in paraspinal muscles of patients with lumbar kyphosis: a preliminary study. / 2018 / PubMed / Full text
  • Leptin stimulates the release of pro-inflammatory cytokines in hypothalamic astrocyte cultures from adult and aged rats. / 12.2018 / PubMed / Full text
  • Effects of 8-week kettlebell training on body composition, muscle strength, pulmonary function, and chronic low-grade inflammation in elderly women with sarcopenia. / 02.10.2018 / PubMed / Full text
  • Research advances in the regulation of the putative ovarian germline stem cell niche on female germline stem cells. / 04.2019 / PubMed / Full text
  • Efficacy and safety of biological agents in the older rheumatoid arthritis patients compared to Young: A systematic review and meta-analysis. / 04.2019 / PubMed / Full text
  • Leptin, hsCRP, TNF-α and IL-6 levels from normal aging to dementia: Relationship with cognitive and functional status. / 10.2018 / PubMed / Full text
  • Systemic Inflammation Mediates Age-Related Cognitive Deficits. / 2018 / PubMed / Full text
  • Featured Article: Deterioration of visual function mediated by senescence-associated endoplasmic reticulum stress in inflammatory tie2-TNF mice. / 08.2018 / PubMed / Full text
  • Quercetin Enhances Ligand-induced Apoptosis in Senescent Idiopathic Pulmonary Fibrosis Fibroblasts and Reduces Lung Fibrosis In Vivo. / 01.2019 / PubMed / Full text
  • Bioactive Peptide Improves Diet-Induced Hepatic Fat Deposition and Hepatocyte Proinflammatory Response in SAMP8 Ageing Mice. / 2018 / PubMed / Full text
  • Senescence and odontoblastic differentiation of dental pulp cells. / 01.2018 / PubMed / Full text
  • Effect of resistance training on inflammatory markers of older adults: A meta-analysis. / 01.10.2018 / PubMed / Full text
  • Heat-induced extracellular HSP72 release is blunted in elderly diabetic people compared with healthy middle-aged and older adults, but it is partially restored by resistance training. / 01.10.2018 / PubMed / Full text
  • Repeated abortion in adulthood induces cognition impairment in aged mice. / 30.07.2018 / PubMed / Full text
  • Cumulus cell-released tumor necrosis factor (TNF)-α promotes post-ovulatory aging of mouse oocytes. / 26.07.2018 / PubMed / Full text
  • Comparison of neurotoxicity of dexmedetomidine as an adjuvant in brachial plexus block in rats of different age. / 09-10.2018 / PubMed / Full text
  • Inflammatory cytokines and immune system modulation by aerobic versus resisted exercise training for elderly. / 03.2018 / PubMed / Full text
  • Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood. / 15.02.2019 / PubMed / Full text
  • Inhibition of programmed necrosis limits infarct size through altered mitochondrial and immune responses in the aged female rat heart. / 01.11.2018 / PubMed / Full text
  • Accumulation of T-helper 22 cells, interleukin-22 and myeloid-derived suppressor cells promotes gastric cancer progression in elderly patients. / 07.2018 / PubMed / Full text
  • Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text
  • The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. / 13.06.2018 / PubMed / Full text
  • Regulation of p38 mitogen-activated kinase-mediated fetal membrane senescence by statins. / 10.2018 / PubMed / Full text
  • Identification of proteins potentially associated with renal aging in rats. / 14.06.2018 / PubMed / Full text
  • Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice. / 2018 / PubMed / Full text
  • Serum Tumor Necrosis Factor-alpha associates with Myocardial Oxygen Demand and Exercise Tolerance in Postmenopausal Women. / 2018 / PubMed / Full text
  • Exercise related anxiety-like behaviours are mediated by TNF receptor signaling, but not depression-like behaviours. / 15.09.2018 / PubMed / Full text
  • Accelerated vascular aging and persistent cognitive impairment in older female breast cancer survivors. / 06.2018 / PubMed / Full text
  • Features of Cytokine Profile in Different Age Groups. / 2014 / PubMed / Full text
  • Anthocyanins Improve Hippocampus-Dependent Memory Function and Prevent Neurodegeneration via JNK/Akt/GSK3β Signaling in LPS-Treated Adult Mice. / 01.2019 / PubMed / Full text
  • Supplementation with eicosapentaenoic acid and docosahexaenoic acid reduces high levels of circulating proinflammatory cytokines in aging adults: A randomized, controlled study. / 05.2018 / PubMed / Full text
  • Effects of nutritional state, aging and high chronic intake of sucrose on brain protein synthesis in rats: modulation of it by rutin and other micronutrients. / 23.05.2018 / PubMed / Full text
  • Plasma zinc in institutionalized elderly individuals: Relation with immune and cardiometabolic biomarkers. / 12.2018 / PubMed / Full text
  • Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. / 2018 / PubMed / Full text
  • Necroptosis increases with age and is reduced by dietary restriction. / 08.2018 / PubMed / Full text
  • Age-Related Changes to Human Tear Composition. / 01.04.2018 / PubMed / Full text
  • Inhibition of UVB-induced pro-inflammatory cytokines and MMP expression by Zanthoxylum rhetsa bark extract and its active constituent hesperidin. / 08.2018 / PubMed / Full text
  • Effects of Baicalein on Cortical Proinflammatory Cytokines and the Intestinal Microbiome in Senescence Accelerated Mouse Prone 8. / 18.07.2018 / PubMed / Full text
  • Probiotic Potential of [i]Enterococcus faecium[/i] Isolated from Chicken Cecum with Immunomodulating Activity and Promoting Longevity in [i]Caenorhabditis elegans[/i]. / 28.06.2018 / PubMed / Full text
  • Sex Differences in Adipose Tissue CD8 T Cells and Regulatory T Cells in Middle-Aged Mice. / 2018 / PubMed / Full text
  • Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation. / 2018 / PubMed / Full text
  • Inosine improves cognitive function and decreases aging-induced oxidative stress and neuroinflammation in aged female rats. / 10.2018 / PubMed / Full text
  • Cytokine Responses to Acute Exercise in Healthy Older Adults: The Effect of Cardiorespiratory Fitness. / 2018 / PubMed / Full text
  • No requirement of interlukine-1 for long-term potentiation in the anterior cingulate cortex of adult mice. / 01-12.2018 / PubMed / Full text
  • [Electroacupuncture Intervention Improves Physical Power of Aged Rats with Low Testosterone by Reducing Chronic Inflammatory Response of Leydig Cells]. / 25.03.2018 / PubMed / Full text
  • Predominant gut Lactobacillus murinus strain mediates anti-inflammaging effects in calorie-restricted mice. / 21.03.2018 / PubMed / Full text
  • Proximity of Cytomegalovirus-Specific CD8 T Cells to Replicative Senescence in Human Immunodeficiency Virus-Infected Individuals. / 2018 / PubMed / Full text
  • Xanthohumol exerts protective effects in liver alterations associated with aging. / 03.2019 / PubMed / Full text
  • Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor. / 2018 / PubMed / Full text
  • Exercise and taurine in inflammation, cognition, and peripheral markers of blood-brain barrier integrity in older women. / 07.2018 / PubMed / Full text
  • Normal aging induces A1-like astrocyte reactivity. / 20.02.2018 / PubMed / Full text
  • Human blood MAIT cell subsets defined using MR1 tetramers. / 05.2018 / PubMed / Full text
  • The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence. / 15.02.2018 / PubMed / Full text
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  • The effect of ladder-climbing exercise on atrophy/hypertrophy-related myokine expression in middle-aged male Wistar rats. / 11.2015 / PubMed / Full text
  • Sleep fragmentation and sepsis differentially impact blood-brain barrier integrity and transport of tumor necrosis factor-α in aging. / 11.2015 / PubMed / Full text
  • Mitochondria-targeted antioxidant SkQ1 improves impaired dermal wound healing in old mice. / 07.2015 / PubMed / Full text
  • Role of vascular peroxidase 1 in senescence of endothelial cells in diabetes rats. / 15.10.2015 / PubMed / Full text
  • [Association between carbonyl proteins and tumor necrosis factor alpha with muscle strength in young and older women: exploratory study]. / 11-12.2015 / PubMed / Full text
  • LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING. / 06.2015 / PubMed
  • Age-Dependent Alterations in the Interactions of NF-κB and N-myc with GLT-1/EAAT2 Promoter in the Pericontusional Cortex of Mice Subjected to Traumatic Brain Injury. / 07.2016 / PubMed / Full text
  • The Werner Protein Acts as a Coactivator of Nuclear Factor κB (NF-κB) on HIV-1 and Interleukin-8 (IL-8) Promoters. / 24.07.2015 / PubMed / Full text
  • Interleukin-6 as a first-rated serum inflammatory marker to predict mortality and hospitalization in the oldest old: A regression and CART approach in the BELFRAIL study. / 09.2015 / PubMed / Full text
  • Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. / 2015 / PubMed / Full text
  • Bile acid mediated effects on gut integrity and performance of early-weaned piglets. / 14.05.2015 / PubMed / Full text
  • Increased serum levels of eotaxin/CCL11 in late-stage patients with bipolar disorder: An accelerated aging biomarker? / 15.08.2015 / PubMed / Full text
  • Vascular endothelial function is improved by oral glycine treatment in aged rats. / 06.2015 / PubMed / Full text
  • Inhibition of hedgehog signalling attenuates UVB-induced skin photoageing. / 08.2015 / PubMed / Full text
  • Age-associated modifications of intestinal permeability and innate immunity in human small intestine. / 10.2015 / PubMed / Full text
  • The stimulatory effect of the TLR4-mediated adjuvant glucopyranosyl lipid A is well preserved in old age. / 02.2016 / PubMed / Full text
  • Inhibiting tumor necrosis factor-α signaling attenuates postoperative cognitive dysfunction in aged rats. / 08.2015 / PubMed / Full text
  • Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by high-fat/high-sucrose feeding at middle age. / 06.2015 / PubMed / Full text
  • [Molecular mechanisms of combined extremely radiofrequency and infrared therapy in various age patients with chronic parodontitis]. / 2014 / PubMed
  • Exercise training increases anabolic and attenuates catabolic and apoptotic processes in aged skeletal muscle of male rats. / 07.2015 / PubMed / Full text
  • Transient early food restriction leads to hypothalamic changes in the long-lived crowded litter female mice. / 04.2015 / PubMed / Full text
  • The probiotic mixture IRT5 ameliorates age-dependent colitis in rats. / 06.2015 / PubMed / Full text
  • Essential role of POLDIP2 in Tau aggregation and neurotoxicity via autophagy/proteasome inhibition. / 26.06.2015 / PubMed / Full text
  • Inflammaging decreases adaptive and innate immune responses in mice and humans. / 02.2016 / PubMed / Full text
  • Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli. / 21.04.2015 / PubMed / Full text
  • Relationship between biomarkers of inflammation, oxidative stress and endothelial/microcirculatory function in successful aging versus healthy youth: a transversal study. / 08.04.2015 / PubMed / Full text
  • No strong correlations between serum cytokine levels, CMV serostatus and hand-grip strength in older subjects in the Berlin BASE-II cohort. / 02.2016 / PubMed / Full text
  • Fibroblast growth factor 21 protects mouse brain against D-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation. / 06.2015 / PubMed / Full text
  • The p53/miR-17/Smurf1 pathway mediates skeletal deformities in an age-related model via inhibiting the function of mesenchymal stem cells. / 03.2015 / PubMed / Full text
  • Acute exercise increases hippocampal TNF-α, Caspase-3 and Caspase-7 expression in healthy young and older mice. / 04.2015 / PubMed
  • Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses. / 07.2015 / PubMed / Full text
  • Autophagy in axonal degeneration in glaucomatous optic neuropathy. / 07.2015 / PubMed / Full text
  • Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal TLR4 activation in aged rats. / 05.2015 / PubMed / Full text
  • Influences of age and sex on leukocytes of healthy horses and their ex vivo cytokine release. / 15.05.2015 / PubMed / Full text
  • Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture. / 05.2015 / PubMed / Full text
  • Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment. / 2015 / PubMed / Full text
  • Association of systemic inflammation with epicardial fat and coronary artery calcification. / 05.2015 / PubMed / Full text
  • Age-associated changes in granulosa cell transcript abundance in equine preovulatory follicles. / 07.2015 / PubMed / Full text
  • Effects of er-miao-san extracts on TNF-alpha-induced MMP-1 expression in human dermal fibroblasts. / 26.01.2015 / PubMed / Full text
  • Immunostimulatory effects of RACK1 pseudosubstrate in human leukocytes obtained from young and old donors. / 30.03.2015 / PubMed / Full text
  • Patient-relevant endpoints in inflammatory bowel diseases--have changes occurred in Germany over the past twelve years? / 05.2015 / PubMed / Full text
  • Anti-inflammatory effect of resveratrol in old mice liver. / 04.2015 / PubMed / Full text
  • Blockade of PD-1 or p38 MAP kinase signaling enhances senescent human CD8( ) T-cell proliferation by distinct pathways. / 05.2015 / PubMed / Full text
  • Circulating TNF and mitochondrial DNA are major determinants of neutrophil phenotype in the advanced-age, frail elderly. / 05.2015 / PubMed / Full text
  • Salidroside protects against premature senescence induced by ultraviolet B irradiation in human dermal fibroblasts. / 06.2015 / PubMed / Full text
  • Selected pro- and anti-inflammatory cytokines in cerebrospinal fluid in normal pressure hydrocephalus. / 2014 / PubMed
  • Vaginal cytokines do not correlate with postmenopausal vulvovaginal symptoms. / 04.2015 / PubMed / Full text
  • Age-related differences in polyfunctional T cell responses. / 2014 / PubMed / Full text
  • Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of D-galactose treated mice. / 02.2015 / PubMed / Full text
  • Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice. / 05.01.2015 / PubMed / Full text
  • Tumor necrosis factor-α-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo. / 01.2015 / PubMed / Full text
  • Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice. / 15.01.2015 / PubMed / Full text
  • Pre-Operative, High-IL-6 Blood Level is a Risk Factor of Post-Operative Delirium Onset in Old Patients. / 2014 / PubMed / Full text
  • Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease. / 2015 / PubMed / Full text
  • Inflammasomes in neuroinflammation and changes in brain function: a focused review. / 2014 / PubMed / Full text
  • Impact of gasless laparoscopy on circulation, respiration, stress response, and other complications in gynecological geriatrics. / 2014 / PubMed / Full text
  • Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice. / 17.11.2014 / PubMed / Full text
  • Sleep deprivation and divergent toll-like receptor-4 activation of cellular inflammation in aging. / 01.02.2015 / PubMed / Full text
  • Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging. / 11.2015 / PubMed / Full text
  • The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice. / 15.12.2014 / PubMed / Full text
  • Evidence for altered inflammatory and repair responses in symptomatic carotid plaques from elderly patients. / 11.2014 / PubMed / Full text
  • Immunosenescence in monocytes, macrophages, and dendritic cells: lessons learned from the lung and heart. / 11.2014 / PubMed / Full text
  • Ferrocifen derivatives that induce senescence in cancer cells: selected examples. / 12.2014 / PubMed / Full text
  • Role of mitochondrial reactive oxygen species in age-related inflammatory activation of endothelium. / 08.2014 / PubMed / Full text
  • Aging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery. / 2014 / PubMed / Full text
  • Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson's disease by laser ablation inductively coupled plasma mass spectrometry. / 20.08.2014 / PubMed / Full text
  • Interleukin-1 deficiency prolongs ovarian lifespan in mice. / 26.08.2014 / PubMed / Full text
  • HIV-1 transgenic rats display alterations in immunophenotype and cellular responses associated with aging. / 2014 / PubMed / Full text
  • Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers. / 01.2015 / PubMed / Full text
  • Relationship between vitamin D and inflammatory markers in older individuals. / 2014 / PubMed / Full text
  • Association of pulse pressure with serum TNF-α and neutrophil count in the elderly. / 2014 / PubMed / Full text
  • Peritoneal exudate cells from long-lived rats exhibit increased IL-10/IL-1β expression ratio and preserved NO/urea ratio following LPS-stimulation in vitro. / 2014 / PubMed / Full text
  • Cortisol, cytokines, and hippocampal volume interactions in the elderly. / 2014 / PubMed / Full text
  • DaoTan decoction (DTD) inhibits tumor necrosis factor-α (TNF-α)-induced expression of intercellular adhesion molecule-1 (ICAM-1), p53 and p21, in human umbilical vein endothelia cells (HUVECs). / 10.2014 / PubMed / Full text
  • Improvement in Th1/Th2 immune homeostasis, antioxidative status and resistance to pathogenic E. coli on consumption of probiotic Lactobacillus rhamnosus fermented milk in aging mice. / 2014 / PubMed / Full text
  • Aging oppositely affects TNF-α and IL-10 production by macrophages from different rat strains. / 2014 / PubMed / Full text
  • Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging. / 2014 / PubMed / Full text
  • iPLA2β knockout mouse, a genetic model for progressive human motor disorders, develops age-related neuropathology. / 08.2014 / PubMed / Full text
  • Site-specific changes in cytokine response to septic dose of lipopolysaccharide in ovariectomized female rats. / 08.2014 / PubMed / Full text
  • D-galactose induced inflammation lipid peroxidation and platelet activation in rats. / 09.2014 / PubMed / Full text
  • Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity. / 05.2014 / PubMed / Full text
  • Bacteria and Toll-like receptor and cytokine mRNA expression profiles associated with canine arthritis. / 15.08.2014 / PubMed / Full text
  • Distinct age-matched serum biomarker profiles in patients with cutaneous T-cell lymphoma. / 08.2014 / PubMed / Full text
  • Age-related activation of MKK/p38/NF-κB signaling pathway in lung: from mouse to human. / 09.2014 / PubMed / Full text
  • Changes in the expression of the Toll-like receptor system in the aging rat kidneys. / 2014 / PubMed / Full text
  • Comparative analysis of low-level laser therapy (660 nm) on inflammatory biomarker expression during the skin wound-repair process in young and aged rats. / 09.2014 / PubMed / Full text
  • Inflammation and prolonged QT time: results from the Cardiovascular Disease, Living and Ageing in Halle (CARLA) study. / 2014 / PubMed / Full text
  • Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state. / 11.2014 / PubMed / Full text
  • Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals. / 08.2014 / PubMed / Full text
  • Maturation of innate responses to mycobacteria over the first nine months of life. / 15.05.2014 / PubMed / Full text
  • Effects of age and macrophage lineage on intracellular survival and cytokine induction after infection with Rhodococcus equi. / 15.07.2014 / PubMed / Full text
  • IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice. / 06.2014 / PubMed / Full text
  • A comparison of pro-inflammatory cytokine mRNA expression in equine bronchoalveolar lavage (BAL) and peripheral blood. / 15.04.2014 / PubMed / Full text
  • Moderate swimming exercise and caffeine supplementation reduce the levels of inflammatory cytokines without causing oxidative stress in tissues of middle-aged rats. / 05.2014 / PubMed / Full text
  • Effects of aging on influenza virus infection dynamics. / 04.2014 / PubMed / Full text
  • Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for "inflamm-aging". / 05.2014 / PubMed / Full text
  • Markers of low-grade inflammation and endothelial dysfunction are related to reduced information processing speed and executive functioning in an older population - the Hoorn Study. / 02.2014 / PubMed / Full text
  • Bacopa monnieri (L.) exerts anti-inflammatory effects on cells of the innate immune system in vitro. / 03.2014 / PubMed / Full text
  • Resveratrol increases antioxidant defenses and decreases proinflammatory cytokines in hippocampal astrocyte cultures from newborn, adult and aged Wistar rats. / 06.2014 / PubMed / Full text
  • High TNF-α levels in resting B cells negatively correlate with their response. / 06.2014 / PubMed / Full text
  • Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life. / 06.2014 / PubMed / Full text

APOEПравить

  • Polygenic risk score of longevity predicts longer survival across an age-continuum. / 20.11.2020 / PubMed / Full text
  • Association Between APOE Alleles and Change of Neuropsychological Tests in the Long Life Family Study. / 17.11.2020 / PubMed / Full text
  • The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans. / 20.11.2020 / PubMed / Full text
  • Homozygosity in the [i]APOE[/i] 3 Polymorphism Is Associated With Less Depression and Higher Serum Low-Density Lipoprotein in Chinese Elderly Schizophrenics. / 2020 / PubMed / Full text
  • Effect of apolipoprotein E polymorphism on cognition and brain in the Cambridge Centre for Ageing and Neuroscience cohort. / 01-12.2020 / PubMed / Full text
  • Cardiovascular risk factors and APOE-ε4 status affect memory functioning in aging via changes to temporal stem diffusion. / 18.10.2020 / PubMed / Full text
  • APOE [i]ε[/i]4 and resting-state functional connectivity in racially/ethnically diverse older adults. / 2020 / PubMed / Full text
  • Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study. / 13.11.2020 / PubMed / Full text
  • When Culture Influences Genes: Positive Age Beliefs Amplify the Cognitive-Aging Benefit of APOE ε2. / 14.09.2020 / PubMed / Full text
  • Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study. / 08.2020 / PubMed / Full text
  • Estimating the potential for dementia prevention through modifiable risk factors elimination in the real-world setting: a population-based study. / 07.08.2020 / PubMed / Full text
  • Machine learning-based estimation of cognitive performance using regional brain MRI markers: the Northern Manhattan Study. / 01.08.2020 / PubMed / Full text
  • Effects of an APOE Promoter Polymorphism on Fronto-Parietal Functional Connectivity During Nondemented Aging. / 2020 / PubMed / Full text
  • The relationship of parental longevity with the aging brain-results from UK Biobank. / 10.2020 / PubMed / Full text
  • Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation. / 30.06.2020 / PubMed / Full text
  • Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer's Disease. / 2020 / PubMed / Full text
  • Effects of sex, age, and apolipoprotein E genotype on hippocampal parenchymal fraction in cognitively normal older adults. / 30.07.2020 / PubMed / Full text
  • Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO). / 05.05.2020 / PubMed / Full text
  • Apolipoprotein E and Health in Older Men: The Concord Health and Ageing in Men Project. / 25.09.2020 / PubMed / Full text
  • CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease. / 07.2020 / PubMed / Full text
  • Association of Cardiovascular Risk Factors with Cerebral Perfusion in Whites and African Americans. / 2020 / PubMed / Full text
  • Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways. / 03.06.2020 / PubMed / Full text
  • Less agreeable, better preserved? A PET amyloid and MRI study in a community-based cohort. / 05.2020 / PubMed / Full text
  • Physical Activity as Moderator of the Association Between APOE and Cognitive Decline in Older Adults: Results from Three Longitudinal Cohort Studies. / 25.09.2020 / PubMed / Full text
  • Longitudinal Maintenance of Cognitive Health in Centenarians in the 100-plus Study. / 05.02.2020 / PubMed / Full text
  • Interaction of APOE, cerebral blood flow, and cortical thickness in the entorhinal cortex predicts memory decline. / 04.2020 / PubMed / Full text
  • Determinants of mesial temporal lobe volume loss in older individuals with preserved cognition: a longitudinal PET amyloid study. / 03.2020 / PubMed / Full text
  • Long-term exposure to ambient air pollution, APOE-ε4 status, and cognitive decline in a cohort of older adults in northern Manhattan. / 03.2020 / PubMed / Full text
  • Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice. / 2020 / PubMed / Full text
  • APOE region molecular signatures of Alzheimer's disease across races/ethnicities. / 03.2020 / PubMed / Full text
  • Varying Effects of APOE Alleles on Extreme Longevity in European Ethnicities. / 13.11.2019 / PubMed / Full text
  • Prospective Evaluation of Cognitive Health and Related Factors in Elderly at Risk for Developing Alzheimer's Dementia: A Longitudinal Cohort Study. / 2019 / PubMed / Full text
  • Association of Cardiovascular and Alzheimer's Disease Risk Factors with Intracranial Arterial Blood Flow in Whites and African Americans. / 2019 / PubMed / Full text
  • Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease? / 17.04.2020 / PubMed / Full text
  • Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study. / 02.2020 / PubMed / Full text
  • Prospective Memory: Age related change is influenced by APOE genotype. / 09.2020 / PubMed / Full text
  • Education Moderates the Relation Between APOE ɛ4 and Memory in Nondemented Non-Hispanic Black Older Adults. / 2019 / PubMed / Full text
  • Apolipoprotein E ε4 allele effects on longitudinal cognitive trajectories are sex and age dependent. / 12.2019 / PubMed / Full text
  • Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects. / 2019 / PubMed / Full text
  • APOE modifies the interaction of entorhinal cerebral blood flow and cortical thickness on memory function in cognitively normal older adults. / 15.11.2019 / PubMed / Full text
  • When time's arrow doesn't bend: APOE-ε4 influences episodic memory before old age. / 10.2019 / PubMed / Full text
  • Cognitive-Motor Integration Performance Is Affected by Sex, APOE Status, and Family History of Dementia. / 2019 / PubMed / Full text
  • Associations among amyloid status, age, and longitudinal regional brain atrophy in cognitively unimpaired older adults. / 10.2019 / PubMed / Full text
  • Cognitive function and neuropathological outcomes: a forward-looking approach. / 12.2019 / PubMed / Full text
  • APOE gene-dependent BOLD responses to a breath-hold across the adult lifespan. / 2019 / PubMed / Full text
  • Medial temporal lobe atrophy and posterior atrophy scales normative values. / 2019 / PubMed / Full text
  • Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study. / 09.2019 / PubMed / Full text
  • Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
  • Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. / 08.2019 / PubMed / Full text
  • Late life insulin resistance and Alzheimer's disease and dementia: The Kuakini Honolulu heart program. / 15.08.2019 / PubMed / Full text
  • Latent Classes of Cognitive Functioning Among Depressed Older Adults Without Dementia. / 09.2019 / PubMed / Full text
  • Lifespan Intellectual Factors, Genetic Susceptibility, and Cognitive Phenotypes in Aging: Implications for Interventions. / 2019 / PubMed / Full text
  • Cyclic O exposure synergizes with aging leading to memory impairment in male APOE ε3, but not APOE ε4, targeted replacement mice. / 09.2019 / PubMed / Full text
  • Alzheimer's disease and symbiotic microbiota: an evolutionary medicine perspective. / 08.2019 / PubMed / Full text
  • The role of APOE in transgenic mouse models of AD. / 10.08.2019 / PubMed / Full text
  • Sex differences in mixed neuropathologies in community-dwelling older adults. / 15.09.2019 / PubMed / Full text
  • Women Outperform Men in Verbal Episodic Memory Even in Oldest-Old Age: 13-Year Longitudinal Results of the AgeCoDe/AgeQualiDe Study. / 2019 / PubMed / Full text
  • APOE Effect on Amyloid-β PET Spatial Distribution, Deposition Rate, and Cut-Points. / 2019 / PubMed / Full text
  • Sex differences in the association of APOE ε4 genotype with longitudinal hippocampal atrophy in cognitively normal older people. / 11.2019 / PubMed / Full text
  • Predictors and Implications of Accelerated Cognitive Aging. / 2018 / PubMed / Full text
  • Association of Cortical β-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease. / 01.07.2019 / PubMed / Full text
  • Sex differences in the association between amyloid and longitudinal brain volume change in cognitively normal older adults. / 2019 / PubMed / Full text
  • Region-specific association between basal blood insulin and cerebral glucose metabolism in older adults. / 2019 / PubMed / Full text
  • Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity. / 10.2020 / PubMed / Full text
  • Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging. / 28.03.2019 / PubMed / Full text
  • Nuances in Alzheimer's Genetic Risk Reveal Differential Predictions of Non-demented Memory Aging Trajectories: Selective Patterns by APOE Genotype and Sex. / 2019 / PubMed / Full text
  • A prospective study of focal brain atrophy, mobility and fitness. / 07.2019 / PubMed / Full text
  • 10-year follow-up of the Super-Seniors Study: compression of morbidity and genetic factors. / 28.02.2019 / PubMed / Full text
  • Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time. / 2019 / PubMed / Full text
  • Taste receptors, innate immunity and longevity: the case of TAS2R16 gene. / 2019 / PubMed / Full text
  • The Role of APOE4 in Disrupting the Homeostatic Functions of Astrocytes and Microglia in Aging and Alzheimer's Disease. / 2019 / PubMed / Full text
  • The influence of tau, amyloid, alpha-synuclein, TDP-43, and vascular pathology in clinically normal elderly individuals. / 05.2019 / PubMed / Full text
  • Opposing Roles of apolipoprotein E in aging and neurodegeneration. / 02.2019 / PubMed / Full text
  • Effects of APOE on cognitive aging in community-dwelling older adults. / 03.2019 / PubMed / Full text
  • A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study. / 05.2019 / PubMed / Full text
  • Apolipoprotein E4 Mediates the Association Between Midlife Dyslipidemia and Cerebral Amyloid in Aging Women. / 2019 / PubMed / Full text
  • Apolipoprotein E gene in physiological and pathological aging. / 03.2019 / PubMed / Full text
  • Spatial patterns of white matter hyperintensities associated with Alzheimer's disease risk factors in a cognitively healthy middle-aged cohort. / 24.01.2019 / PubMed / Full text
  • The Role of MRI Biomarkers and Their Interactions with Cognitive Status and APOE ε4 in Nondemented Elderly Subjects. / 2018 / PubMed / Full text
  • Longitudinal tau accumulation and atrophy in aging and alzheimer disease. / 02.2019 / PubMed / Full text
  • Apolipoprotein E Genotypes, Age, Race, and Cognitive Decline in a Population Sample. / 04.2019 / PubMed / Full text
  • Predictors of neurodegeneration differ between cognitively normal and subsequently impaired older adults. / 03.2019 / PubMed / Full text
  • Vascular burden and APOE ε4 are associated with white matter microstructural decline in cognitively normal older adults. / 03.2019 / PubMed / Full text
  • Responses to executive demand in young adulthood differ by APOE genotype. / 15.03.2019 / PubMed / Full text
  • Mild Cognitive Impairment that Does Not Progress to Dementia: A Population-Based Study. / 02.2019 / PubMed / Full text
  • Neuropathologic, genetic, and longitudinal cognitive profiles in primary age-related tauopathy (PART) and Alzheimer's disease. / 01.2019 / PubMed / Full text
  • Independent associations of TOMM40 and APOE variants with body mass index. / 02.2019 / PubMed / Full text
  • Apolipoprotein E genotype moderates the association between dietary polyunsaturated fat and brain function: an exploration of cerebral glutamate and cognitive performance. / 09.2020 / PubMed / Full text
  • Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults. / 09.2018 / PubMed / Full text
  • The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description. / 12.2018 / PubMed / Full text
  • Report: NIA workshop on translating genetic variants associated with longevity into drug targets. / 12.2018 / PubMed / Full text
  • Dendritic spine remodeling accompanies Alzheimer's disease pathology and genetic susceptibility in cognitively normal aging. / 01.2019 / PubMed / Full text
  • The ApoE ε4 Isoform: Can the Risk of Diseases be Reduced by Environmental Factors? / 01.01.2019 / PubMed / Full text
  • Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text
  • Amygdala subnuclei and healthy cognitive aging. / 01.2019 / PubMed / Full text
  • APOE ɛ4, rs405509, and rs440446 promoter and intron-1 polymorphisms and dementia risk in a cohort of elderly Finns-Helsinki Birth Cohort Study. / 01.2019 / PubMed / Full text
  • The Cross-sectional and Longitudinal Associations Between IL-6, IL-10, and TNFα and Cognitive Outcomes in the Mayo Clinic Study of Aging. / 12.07.2019 / PubMed / Full text
  • The effect of midlife cardiovascular risk factors on white matter hyperintensity volume and cognition two decades later in normal ageing women. / 02.2020 / PubMed / Full text
  • Sex and age interact to determine clinicopathologic differences in Alzheimer's disease. / 12.2018 / PubMed / Full text
  • Relationship Between Amyloid-β Positivity and Progression to Mild Cognitive Impairment or Dementia over 8 Years in Cognitively Normal Older Adults. / 2018 / PubMed / Full text
  • Lifetime Risk Factors for Functional and Cognitive Outcomes in Patients with Alzheimer's Disease. / 2018 / PubMed / Full text
  • Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau. / 03.09.2018 / PubMed / Full text
  • Childhood socioeconomic status and genetic risk for poorer cognition in later life. / 09.2018 / PubMed / Full text
  • Diffuse Amyloid-β Plaques, Neurofibrillary Tangles, and the Impact of APOE in Elderly Persons' Brains Lacking Neuritic Amyloid Plaques. / 2018 / PubMed / Full text
  • Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain. / 24.07.2018 / PubMed / Full text
  • Dual-Task Gait and Alzheimer's Disease Genetic Risk in Cognitively Normal Adults: A Pilot Study. / 2018 / PubMed / Full text
  • Higher Aortic Stiffness Is Related to Lower Cerebral Blood Flow and Preserved Cerebrovascular Reactivity in Older Adults. / 30.10.2018 / PubMed / Full text
  • Physical activity effects on the individual alpha peak frequency of older adults with and without genetic risk factors for Alzheimer's Disease: A MEG study. / 09.2018 / PubMed / Full text
  • Racial and Ethnic Disparities in Dementia Risk Among Individuals With Low Education. / 09.2018 / PubMed / Full text
  • Increased CAIDE dementia risk, cognition, CSF biomarkers, and vascular burden in healthy adults. / 17.07.2018 / PubMed / Full text
  • Differential 5-year brain atrophy rates in cognitively declining and stable APOE-ε4 elders. / 09.2018 / PubMed / Full text
  • Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. / 10.2018 / PubMed / Full text
  • Using event-related fMRI to examine sustained attention processes and effects of APOE ε4 in young adults. / 2018 / PubMed / Full text
  • Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age. / 2018 / PubMed / Full text
  • White matter microstructure is altered in cognitively normal middle-aged APOE-ε4 homozygotes. / 24.05.2018 / PubMed / Full text
  • Effects of lifetime cumulative ginseng intake on cognitive function in late life. / 24.05.2018 / PubMed / Full text
  • Apolipoprotein E region molecular signatures of Alzheimer's disease. / 08.2018 / PubMed / Full text
  • Does incipient dementia explain normal cognitive decline determinants? Lothian birth cohort 1921. / 06.2018 / PubMed / Full text
  • An 18-mo randomized, double-blind, placebo-controlled trial of DHA-rich fish oil to prevent age-related cognitive decline in cognitively normal older adults. / 01.05.2018 / PubMed / Full text
  • The Role of Apolipoprotein E and Ethanol Exposure in Age-Related Changes in Choline Acetyltransferase and Brain-Derived Neurotrophic Factor Expression in the Mouse Hippocampus. / 05.2018 / PubMed / Full text
  • APOE genotype modifies the association between central arterial stiffening and cognition in older adults. / 07.2018 / PubMed / Full text
  • Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration. / 2018 / PubMed / Full text
  • Brain Aging and APOE ε4 Interact to Reveal Potential Neuronal Compensation in Healthy Older Adults. / 2018 / PubMed / Full text
  • Leisure-Time Physical Activity and the Risk of Incident Dementia: The Mayo Clinic Study of Aging. / 2018 / PubMed / Full text
  • Effects of APOE-ε4 allele load on brain morphology in a cohort of middle-aged healthy individuals with enriched genetic risk for Alzheimer's disease. / 07.2018 / PubMed / Full text
  • APOE influences working memory in non-demented elderly through an interaction with SPON1 rs2618516. / 07.2018 / PubMed / Full text
  • Altered effective connectivity anchored in the posterior cingulate cortex and the medial prefrontal cortex in cognitively intact elderly APOE ε4 carriers: a preliminary study. / 02.2019 / PubMed / Full text
  • Plasma Cortisol, Brain Amyloid-β, and Cognitive Decline in Preclinical Alzheimer's Disease: A 6-Year Prospective Cohort Study. / 01.2017 / PubMed / Full text
  • Apolipoprotein E genotypes and longevity across dementia disorders. / 07.2018 / PubMed / Full text
  • Differential Effect of APOE ɛ4 Status and Elevated Pulse Pressure on Functional Decline in Cognitively Normal Older Adults. / 2018 / PubMed / Full text
  • Functional segregation loss over time is moderated by APOE genotype in healthy elderly. / 07.2018 / PubMed / Full text
  • Dementia Prevalence in Greece: The Hellenic Longitudinal Investigation of Aging and Diet (HELIAD). / 07-09.2018 / PubMed / Full text
  • Atypical Localization and Dissociation between Glucose Uptake and Amyloid Deposition in Cognitively Normal APOE*E4 Homozygotic Elders Compared with Patients with Late-Onset Alzheimer's Disease. / 01-02.2018 / PubMed / Full text
  • Association between subjective memory assessment and associative memory performance: Role of ad risk factors. / 02.2018 / PubMed / Full text
  • Reduced Gray Matter Volume of the Thalamus and Hippocampal Region in Elderly Healthy Adults with no Impact of APOE ɛ4: A Longitudinal Voxel-Based Morphometry Study. / 2018 / PubMed / Full text
  • Apolipoprotein E genotype does not moderate the associations of depressive symptoms, neuroticism and allostatic load with cognitive ability and cognitive aging in the Lothian Birth Cohort 1936. / 2018 / PubMed / Full text
  • A Network of Genetic Effects on Non-Demented Cognitive Aging: Alzheimer's Genetic Risk (CLU CR1   PICALM) Intensifies Cognitive Aging Genetic Risk (COMT BDNF) Selectively for APOEɛ4 Carriers. / 2018 / PubMed / Full text
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  • APOE ε4 Genotype and Cognitive Reserve Effects on the Cognitive Functioning of Healthy Elders. / 2017 / PubMed / Full text
  • Distinct neural correlates of episodic memory among apolipoprotein E alleles in cognitively normal elderly. / 02.2019 / PubMed / Full text
  • Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis. / 06.12.2017 / PubMed / Full text
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  • Green space and cognitive ageing: A retrospective life course analysis in the Lothian Birth Cohort 1936. / 01.2018 / PubMed / Full text
  • Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations. / 23.10.2017 / PubMed / Full text
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  • The Association of Apolipoprotein E Gene Polymorphism With Cognitive Performance in Nondemented Polish Adults Aged 55 to 75. / 09.2018 / PubMed / Full text
  • Cognitive Aging in Black and White Americans: Cognition, Cognitive Decline, and Incidence of Alzheimer Disease Dementia. / 01.2018 / PubMed / Full text
  • Alzheimer's Disease Biomarkers Interactively Influence Physical Activity, Mobility, and Cognition Associations in a Non-Demented Aging Population. / 2017 / PubMed / Full text
  • Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort. / 2017 / PubMed / Full text
  • Putting attention in the spotlight: The influence of APOE genotype on visual search in mid adulthood. / 15.09.2017 / PubMed / Full text
  • Left Frontal Hub Connectivity during Memory Performance Supports Reserve in Aging and Mild Cognitive Impairment. / 2017 / PubMed / Full text
  • Physical activity modifies the influence of apolipoprotein E ε4 allele and type 2 diabetes on dementia and cognitive impairment among older Mexican Americans. / 01.2018 / PubMed / Full text
  • Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition. / 2017 / PubMed / Full text
  • Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults. / 03.07.2017 / PubMed / Full text
  • Differential Aging Trajectories of Modulation of Activation to Cognitive Challenge in APOE ε4 Groups: Reduced Modulation Predicts Poorer Cognitive Performance. / 19.07.2017 / PubMed / Full text
  • Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults. / 09.2017 / PubMed / Full text
  • APOE gene polymorphism in long-lived individuals from a central China population. / 12.06.2017 / PubMed / Full text
  • Disrupted white matter structural networks in healthy older adult APOE ε4 carriers - An international multicenter DTI study. / 15.08.2017 / PubMed / Full text
  • Effect of APOE ε4 Genotype on Metabolic Biomarkers in Aging and Alzheimer's Disease. / 2017 / PubMed / Full text
  • APOE moderates compensatory recruitment of neuronal resources during working memory processing in healthy older adults. / 08.2017 / PubMed / Full text
  • General cognitive status among Baby boomers and pre-boomers in Taiwan: the interplay between mid-life socioeconomic status and city residence. / 25.05.2017 / PubMed / Full text
  • APOE ε4 Modulation of Training Outcomes in Several Cognitive Domains in a Sample of Cognitively Intact Older Adults. / 2017 / PubMed / Full text
  • APOE Genotype and Nonrespiratory Sleep Parameters in Cognitively Intact Older Adults. / 01.08.2017 / PubMed / Full text
  • The APOE ε4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease. / 19.07.2017 / PubMed / Full text
  • Cognitive Domain Dispersion Association with Alzheimer's Disease Pathology. / 2017 / PubMed / Full text
  • Evaluation of Amyloid Protective Factors and Alzheimer Disease Neurodegeneration Protective Factors in Elderly Individuals. / 01.06.2017 / PubMed / Full text
  • Plasma apolipoproteins and physical and cognitive health in very old individuals. / 07.2017 / PubMed / Full text
  • Youthful Processing Speed in Older Adults: Genetic, Biological, and Behavioral Predictors of Cognitive Processing Speed Trajectories in Aging. / 2017 / PubMed / Full text
  • Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases. / 01.04.2017 / PubMed / Full text
  • Aberrant interhemispheric functional connectivity within default mode network and its relationships with neurocognitive features in cognitively normal APOE ε 4 elderly carriers. / 05.2017 / PubMed / Full text
  • Association between tau deposition and antecedent amyloid-β accumulation rates in normal and early symptomatic individuals. / 01.05.2017 / PubMed / Full text
  • Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73 to 76. / 06.2017 / PubMed / Full text
  • Convergent and divergent effects of apolipoprotein E ε4 and ε2 alleles on amygdala functional networks in nondemented older adults. / 06.2017 / PubMed / Full text
  • Effect of age and the APOE gene on metabolite concentrations in the posterior cingulate cortex. / 15.05.2017 / PubMed / Full text
  • Modulation of Retinal Arteriolar Central Reflection by APOE Genotype. / 2017 / PubMed / Full text
  • Prospective associations of exercise and depressive symptoms in older adults: the role of apolipoprotein E4. / 07.2017 / PubMed / Full text
  • Psychosocial Risk and Protective Factors and Incident Mild Cognitive Impairment and Dementia in Community Dwelling Elderly: Findings from the Singapore Longitudinal Ageing Study. / 2017 / PubMed / Full text
  • Demographic, phenotypic, and genetic characteristics of centenarians in Okinawa and Honshu, Japan: Part 2 Honshu, Japan. / 07.2017 / PubMed / Full text
  • Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
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  • Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old. / 28.03.2017 / PubMed / Full text
  • A Multi-Cohort Study of ApoE ɛ4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease. / 2017 / PubMed / Full text
  • The rs1277306 Variant of the REST Gene Confers Susceptibility to Cognitive Aging in an Elderly Taiwanese Population. / 2017 / PubMed / Full text
  • The Interactive Effects of Age and PICALM rs541458 Polymorphism on Cognitive Performance, Brain Structure, and Function in Non-demented Elderly. / 02.2018 / PubMed / Full text
  • Age differences in arterial and venous extra-cerebral blood flow in healthy adults: contributions of vascular risk factors and genetic variants. / 08.2017 / PubMed / Full text
  • High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors. / 01.2017 / PubMed / Full text
  • Executive function performance and change in aging is predicted by apolipoprotein E, intensified by catechol-O-methyltransferase and brain-derived neurotrophic factor, and moderated by age and lifestyle. / 04.2017 / PubMed / Full text
  • The Elusive Nature of APOE ε4 in Mid-adulthood: Understanding the Cognitive Profile. / 03.2017 / PubMed / Full text
  • Motor timing intraindividual variability in amnestic mild cognitive impairment and cognitively intact elders at genetic risk for Alzheimer's disease. / 11.2017 / PubMed / Full text
  • Screening Younger Individuals in a Primary Care Setting Flags Putative Dementia Cases and Correlates Gastrointestinal Diseases with Poor Cognitive Performance. / 2017 / PubMed / Full text
  • The integration of epigenetics and genetics in nutrition research for CVD risk factors. / 08.2017 / PubMed / Full text
  • Latent structure of cognitive performance in the adult children study. / 09.2017 / PubMed / Full text
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  • Association of Brain Amyloid-β With Slow Gait in Elderly Individuals Without Dementia: Influence of Cognition and Apolipoprotein E ε4 Genotype. / 01.01.2017 / PubMed / Full text
  • Effect of the Interplay Between Genetic and Behavioral Risks on Survival After Age 75. / 12.2016 / PubMed / Full text
  • Homocysteine and Real-Space Navigation Performance among Non-Demented Older Adults. / 2017 / PubMed / Full text
  • Obesity, Apolipoprotein E ε4, and Difficulties in Activities of Daily Living Among Older Adults: a 6-Year Follow-up Study. / 04.2017 / PubMed / Full text
  • Comparison of Gait Parameters for Predicting Cognitive Decline: The Mayo Clinic Study of Aging. / 2017 / PubMed / Full text
  • The APOE paradox: do attentional control differences in mid-adulthood reflect risk of late-life cognitive decline. / 12.2016 / PubMed / Full text
  • Relative effect of APOE ε4 on neuroimaging biomarker changes across the lifespan. / 18.10.2016 / PubMed / Full text
  • The Effects of an APOE Promoter Polymorphism on Human White Matter Connectivity during Non-Demented Aging. / 2017 / PubMed / Full text
  • Dopamine Receptor Genes Modulate Associative Memory in Old Age. / 02.2017 / PubMed / Full text
  • Precuneus degeneration in nondemented elderly individuals with APOE ɛ4: Evidence from structural and functional MRI analyses. / 01.2017 / PubMed / Full text
  • Effects of the APOE ε4 allele and education on cognitive function in Japanese centenarians. / 12.2016 / PubMed / Full text
  • Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. / 2016 / PubMed / Full text
  • Mixed brain lesions mediate the association between cardiovascular risk burden and cognitive decline in old age: A population-based study. / 03.2017 / PubMed / Full text
  • Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age. / 08.2016 / PubMed / Full text
  • Neuritic and Diffuse Plaque Associations with Memory in Non-Cognitively Impaired Elderly. / 14.07.2016 / PubMed / Full text
  • White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration. / 2016 / PubMed / Full text
  • APOE ε4 allele modifies the association of lead exposure with age-related cognitive decline in older individuals. / 11.2016 / PubMed / Full text
  • APOE genotype and stress response - a mini review. / 25.07.2016 / PubMed / Full text
  • An Alzheimer's Disease Genetic Risk Score Predicts Longitudinal Thinning of Hippocampal Complex Subregions in Healthy Older Adults. / 05-06.2016 / PubMed / Full text
  • Levels of tau protein in plasma are associated with neurodegeneration and cognitive function in a population-based elderly cohort. / 12.2016 / PubMed / Full text
  • FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. / 14.07.2016 / PubMed / Full text
  • Affect of APOE on information processing speed in non-demented elderly population: a preliminary structural MRI study. / 08.2017 / PubMed / Full text
  • Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy. / 15.10.2016 / PubMed / Full text
  • The effect of β-amyloid positivity on cerebral metabolism in cognitively normal seniors. / 12.2016 / PubMed / Full text
  • The Effect of the APOE Genotype on Individual BrainAGE in Normal Aging, Mild Cognitive Impairment, and Alzheimer's Disease. / 2016 / PubMed / Full text
  • Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice. / 12.07.2016 / PubMed / Full text
  • Gray matter maturation and cognition in children with different APOE ε genotypes. / 09.08.2016 / PubMed / Full text
  • The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and APOE. / 02.08.2016 / PubMed / Full text
  • Impact of Personality on Cognitive Aging: A Prospective Cohort Study. / 08.2016 / PubMed / Full text
  • Changes in Frailty Predict Changes in Cognition in Older Men: The Honolulu-Asia Aging Study. / 15.06.2016 / PubMed / Full text
  • APOE and aging-related cognitive change in a longitudinal cohort of men. / 08.2016 / PubMed / Full text
  • Braak stage and trajectory of cognitive decline in noncognitively impaired elders. / 07.2016 / PubMed / Full text
  • Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models. / 30.03.2017 / PubMed / Full text
  • Global hypoxia induced impairment in learning and spatial memory is associated with precocious hippocampal aging. / 09.2016 / PubMed / Full text
  • Selective familiarity deficits in otherwise cognitively intact aging individuals with genetic risk for Alzheimer's disease. / 2016 / PubMed / Full text
  • Blood glucose levels and cortical thinning in cognitively normal, middle-aged adults. / 15.06.2016 / PubMed / Full text
  • Relationship between APOE Genotype and Structural MRI Measures throughout Adulthood in the Study of Health in Pomerania Population-Based Cohort. / 09.2016 / PubMed / Full text
  • Waist circumference is correlated with poorer cognition in elderly type 2 diabetes women. / 08.2016 / PubMed / Full text
  • Risk-reducing Apolipoprotein E and Clusterin genotypes protect against the consequences of poor vascular health on executive function performance and change in nondemented older adults. / 06.2016 / PubMed / Full text
  • Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants. / 07.2016 / PubMed / Full text
  • APOE4 Induces Site-Specific Tau Phosphorylation Through Calpain-CDK5 Signaling Pathway in EFAD-Tg Mice. / 2016 / PubMed / Full text
  • Cardiometabolic risk factors predict cerebrovascular health in older adults: results from the Brain in Motion study. / 04.2016 / PubMed / Full text
  • Dementia Risk and Protective Factors Differ in the Context of Memory Trajectory Groups. / 12.04.2016 / PubMed / Full text
  • Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan. / 31.03.2016 / PubMed / Full text
  • Age, APOE and sex: Triad of risk of Alzheimer's disease. / 06.2016 / PubMed / Full text
  • Occupational cognitive requirements and late-life cognitive aging. / 12.04.2016 / PubMed / Full text
  • Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease. / 05.2016 / PubMed / Full text
  • Genetic landscape of APOE in human longevity revealed by high-throughput sequencing. / 04.2016 / PubMed / Full text
  • No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes. / 06.2016 / PubMed / Full text
  • Lack of neural compensatory mechanisms of BDNF val66met met carriers and APOE E4 carriers in healthy aging, mild cognitive impairment, and Alzheimer's disease. / 03.2016 / PubMed / Full text
  • Novel loci and pathways significantly associated with longevity. / 25.02.2016 / PubMed / Full text
  • White matter hyperintensities and imaging patterns of brain ageing in the general population. / 04.2016 / PubMed / Full text
  • Characterization of Amyloid-β Deposits in Bovine Brains. / 2016 / PubMed / Full text
  • The role of APOE in cerebrovascular dysfunction. / 05.2016 / PubMed / Full text
  • Decreased Inter-Hemispheric Functional Connectivity in Cognitively Intact Elderly APOE ɛ4 Carriers: A Preliminary Study. / 2016 / PubMed / Full text
  • APOE ε4 associated with preserved executive function performance and maintenance of temporal and cingulate brain volumes in younger adults. / 02.2017 / PubMed / Full text
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  • The APOE epsilon 4 polymorphism does not predict late onset depression: the Three-City Study. / 04.2016 / PubMed / Full text
  • High homocysteine and epistasis between MTHFR and APOE: association with cognitive performance in the elderly. / 04.2016 / PubMed / Full text
  • The Relationship Between Plasma Aβ Levels, Cognitive Function and Brain Volumetrics: Sydney Memory and Ageing Study. / 2016 / PubMed / Full text
  • Braak staging, plaque pathology, and APOE status in elderly persons without cognitive impairment. / 01.2016 / PubMed / Full text
  • Biomarkers of cholesterol homeostasis in a clinical laboratory database sample comprising 667,718 patients. / 11-12.2015 / PubMed / Full text
  • Genetic factors and epigenetic mechanisms of longevity: current perspectives. / 2015 / PubMed / Full text
  • Subjective Memory Complaints in APOEɛ4 Carriers are Associated with High Amyloid-β Burden. / 2016 / PubMed / Full text
  • Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: the modulating effects of older age and disease severity. / 2013 / PubMed / Full text
  • Individual estimates of age at detectable amyloid onset for risk factor assessment. / 04.2016 / PubMed / Full text
  • Influence of amyloid and APOE on cognitive performance in a late middle-aged cohort. / 03.2016 / PubMed / Full text
  • Gene-Environment Interplay in Physical, Psychological, and Cognitive Domains in Mid to Late Adulthood: Is APOE a Variability Gene? / 01.2016 / PubMed / Full text
  • Predictors of Cognitive and Functional Decline in Patients With Alzheimer Disease Dementia From Brazil. / 07-09.2016 / PubMed / Full text
  • APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction. / 10.2015 / PubMed / Full text
  • Association of APOE with tau-tangle pathology with and without β-amyloid. / 01.2016 / PubMed / Full text
  • APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration. / 07.10.2015 / PubMed / Full text
  • The Role of Alzheimer's and Cerebrovascular Pathology in Mediating the Effects of Age, Race, and Apolipoprotein E Genotype on Dementia Severity in Pathologically-Confirmed Alzheimer's Disease. / 2016 / PubMed / Full text
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  • Ankle-Brachial Index but Neither Intima Media Thickness Nor Coronary Artery Calcification is Associated With Mild Cognitive Impairment. / 2015 / PubMed / Full text
  • No difference in paired associative stimulation induced cortical neuroplasticity between patients with mild cognitive impairment and elderly controls. / 02.2016 / PubMed / Full text
  • Comparison of ApoE-related brain connectivity differences in early MCI and normal aging populations: an fMRI study. / 12.2016 / PubMed / Full text
  • Effects of APOE rs429358, rs7412 and GSTM1/GSTT1 Polymorphism on Plasma and Erythrocyte Antioxidant Parameters and Cognition in Old Chinese Adults. / 24.09.2015 / PubMed / Full text
  • Does apolipoprotein E genotype influence cognition in middle-aged individuals? / 12.2015 / PubMed / Full text
  • Diabetes is Associated with Worse Executive Function in Both Eastern and Western Populations: Shanghai Aging Study and Mayo Clinic Study of Aging. / 2015 / PubMed / Full text
  • APOE Affects the Volume and Shape of the Amygdala and the Hippocampus in Mild Cognitive Impairment and Alzheimer's Disease: Age Matters. / 2015 / PubMed / Full text
  • APOE-by-sex interactions on brain structure and metabolism in healthy elderly controls. / 29.09.2015 / PubMed / Full text
  • APOE Genotype Affects Cognitive Training Response in Healthy Shanghai Community-Dwelling Elderly Individuals. / 2015 / PubMed / Full text
  • Association of White Matter Integrity and Cognitive Functions in Chinese Non-Demented Elderly with the APOE ɛ4 Allele. / 2015 / PubMed / Full text
  • Vascular Health and Genetic Risk Affect Mild Cognitive Impairment Status and 4-Year Stability: Evidence From the Victoria Longitudinal Study. / 11.2016 / PubMed / Full text
  • Apolipoprotein E and Clusterin can magnify effects of personality vulnerability on declarative memory performance in non-demented older adults. / 05.2016 / PubMed / Full text
  • Examining the association between Apolipoprotein E (APOE) and self-reported sleep disturbances in non-demented older adults. / 08.10.2015 / PubMed / Full text
  • G×E Interaction Influences Trajectories of Hand Grip Strength. / 01.2016 / PubMed / Full text
  • Effects of APOE promoter polymorphism on the topological organization of brain structural connectome in nondemented elderly. / 12.2015 / PubMed / Full text
  • Interactive effects of physical activity and APOE-ε4 on white matter tract diffusivity in healthy elders. / 01.05.2016 / PubMed / Full text
  • Brain Amyloid Deposition and Longitudinal Cognitive Decline in Nondemented Older Subjects: Results from a Multi-Ethnic Population. / 2015 / PubMed / Full text
  • DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) genes are associated with anxiety/depression in older women. / 2015 / PubMed / Full text
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  • Anterior cingulate cortex mediates the relationship between O3PUFAs and executive functions in APOE e4 carriers. / 2015 / PubMed / Full text
  • Current versus lifetime depression, APOE variation, and their interaction on cognitive performance in younger and older adults. / 06.2015 / PubMed / Full text
  • Aging, Practice Effects, and Genetic Risk in the Wisconsin Registry for Alzheimer's Prevention. / 2015 / PubMed / Full text
  • Glucose Dysregulation Interacts With APOE-∊4 to Potentiate Temporoparietal Cortical Thinning. / 02.2016 / PubMed / Full text
  • Spatial pattern separation differences in older adult carriers and non-carriers for the apolipoprotein E epsilon 4 allele. / 03.2016 / PubMed / Full text
  • GWAS and Meta-Analysis in Aging/Longevity. / 2015 / PubMed / Full text
  • Odor identification and Alzheimer disease biomarkers in clinically normal elderly. / 26.05.2015 / PubMed / Full text
  • Aging, Alzheimer's, and APOE genotype influence the expression and neuronal distribution patterns of microtubule motor protein dynactin-P50. / 2015 / PubMed / Full text
  • Interaction of Cigarette Smoking History With APOE Genotype and Age on Amyloid Level, Glucose Metabolism, and Neurocognition in Cognitively Normal Elders. / 02.2016 / PubMed / Full text
  • APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice. / 05.03.2015 / PubMed / Full text
  • APOE ε4 Genotype and the Risk for Subjective Cognitive Impairment in Elderly Persons. / Fall.2015 / PubMed / Full text
  • Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of Aging. / 07.04.2015 / PubMed / Full text
  • The identification of cognitive subtypes in Alzheimer's disease dementia using latent class analysis. / 03.2016 / PubMed / Full text
  • Age, Sex, and APOE ε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span. / 05.2015 / PubMed / Full text
  • Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults. / 2015 / PubMed / Full text
  • Bone mineral density, adiposity, and cognitive functions. / 2015 / PubMed / Full text
  • Buccal cell cytokeratin 14 identifies mild cognitive impairment and Alzheimer' s disease in the AIBL study of aging. / 2015 / PubMed / Full text
  • Traumatic brain injury and late-life dementia. / 2015 / PubMed / Full text
  • Are the effects of APOE ϵ4 on cognitive function in nonclinical populations age- and gender-dependent? / 2015 / PubMed / Full text
  • Interactive effect of APOE genotype and blood pressure on cognitive decline: the PATH through life study. / 2015 / PubMed / Full text
  • Sex-based memory advantages and cognitive aging: a challenge to the cognitive reserve construct? / 02.2015 / PubMed / Full text
  • DNA methylation age of blood predicts all-cause mortality in later life. / 30.01.2015 / PubMed / Full text
  • The effects of an APOE promoter polymorphism on human cortical morphology during nondemented aging. / 28.01.2015 / PubMed / Full text
  • Cognitive resilience to apolipoprotein E ε4: contributing factors in black and white older adults. / 03.2015 / PubMed / Full text
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  • Genetic variants modify the effect of age on APOE methylation in the Genetics of Lipid Lowering Drugs and Diet Network study. / 02.2015 / PubMed / Full text
  • Genetic factors associated with longevity: a review of recent findings. / 01.2015 / PubMed / Full text
  • Telomerase Gene (hTERT) and Survival: Results From Two Swedish Cohorts of Older Adults. / 02.2016 / PubMed / Full text
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  • Opposite Neural Trajectories of Apolipoprotein E ϵ4 and ϵ2 Alleles with Aging Associated with Different Risks of Alzheimer's Disease. / 04.2016 / PubMed / Full text
  • Resting-state functional connectivity changes in aging apoE4 and apoE-KO mice. / 15.10.2014 / PubMed / Full text
  • Disease variants in genomes of 44 centenarians. / 09.2014 / PubMed / Full text
  • Longitudinal trajectories of cholesterol from midlife through late life according to apolipoprotein E allele status. / 16.10.2014 / PubMed / Full text
  • Influence of the APOE ε4 allele and mild cognitive impairment diagnosis in the disruption of the MEG resting state functional connectivity in sources space. / 2015 / PubMed / Full text
  • Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity? / 23.09.2014 / PubMed / Full text
  • Self-reported memory complaints: implications from a longitudinal cohort with autopsies. / 07.10.2014 / PubMed / Full text
  • The interaction of APOE genotype by age in amnestic mild cognitive impairment: a voxel-based morphometric study. / 2015 / PubMed / Full text
  • APOE ε4 allele is associated with worse performance in memory dimensions of the mini-mental state examination: the Bambuí Cohort Study of Aging. / 06.2015 / PubMed / Full text
  • Influence of multiple APOE genetic variants on cognitive function in a cohort of older men - results from the Normative Aging Study. / 01.08.2014 / PubMed / Full text
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  • Lack of effect of the apolipoprotein E ε4 genotype on cognition during healthy aging. / 2014 / PubMed / Full text
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  • Structure and correlates of cognitive aging in a narrow age cohort. / 06.2014 / PubMed / Full text
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  • Hypertension moderates the effect of APOE on 21-year cognitive trajectories. / 06.2014 / PubMed / Full text
  • APOE and BDNF Val66Met polymorphisms combine to influence episodic memory function in older adults. / 01.09.2014 / PubMed / Full text
  • Genetic variants in PVRL2-TOMM40-APOE region are associated with human longevity in a Han Chinese population. / 2014 / PubMed / Full text
  • Life experience and demographic influences on cognitive function in older adults. / 11.2014 / PubMed / Full text
  • APOE-epsilon4 and aging of medial temporal lobe gray matter in healthy adults older than 50 years. / 11.2014 / PubMed / Full text
  • Apolipoprotein E Allele and Hearing Thresholds in Older Adults. / 02.2016 / PubMed / Full text
  • Differential clinicopathologic and genetic features of late-onset amnestic dementias. / 09.2014 / PubMed / Full text
  • Late-life cynical distrust, risk of incident dementia, and mortality in a population-based cohort. / 17.06.2014 / PubMed / Full text
  • Longitudinal change in working memory as a function of APOE genotype in midlife and old age. / 06.2014 / PubMed / Full text
  • APOE moderates the association between lifestyle activities and cognitive performance: evidence of genetic plasticity in aging. / 05.2014 / PubMed / Full text
  • Effects of APOE ε4, age, and HIV on glial metabolites and cognitive deficits. / 17.06.2014 / PubMed / Full text
  • Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals. / 09.2014 / PubMed / Full text
  • Association of hypometabolism and amyloid levels in aging, normal subjects. / 03.06.2014 / PubMed / Full text
  • Association of apolipoprotein E-e4 and dementia declines with age. / 10.2014 / PubMed / Full text
  • No evidence of a longitudinal association between diurnal cortisol patterns and cognition. / 10.2014 / PubMed / Full text
  • Gene-gene interaction between CETP and APOE polymorphisms confers higher risk for hypertriglyceridemia in oldest-old Chinese women. / 07.2014 / PubMed / Full text
  • Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease. / 20.05.2014 / PubMed / Full text
  • Differences in age-related effects on brain volume in Down syndrome as compared to Williams syndrome and typical development. / 2014 / PubMed / Full text
  • 18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons. / 09.2014 / PubMed / Full text
  • ACE polymorphism and use of ACE inhibitors: effects on memory performance. / 06.2014 / PubMed / Full text
  • Exercise, APOE genotype, and the evolution of the human lifespan. / 05.2014 / PubMed / Full text
  • Long-term cognitive correlates of traumatic brain injury across adulthood and interactions with APOE genotype, sex, and age cohorts. / 04.2014 / PubMed / Full text
  • The benefits of staying active in old age: physical activity counteracts the negative influence of PICALM, BIN1, and CLU risk alleles on episodic memory functioning. / 06.2014 / PubMed / Full text
  • Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. / 2014 / PubMed / Full text
  • Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculature. / 21.03.2014 / PubMed / Full text
  • [Clinical and genetic characteristics of long-livers in Moscow region]. / 2013 / PubMed
  • Cortical ¹¹C-PIB uptake is associated with age, APOE genotype, and gender in "healthy aging". / 2014 / PubMed / Full text
  • Prevalence of mild cognitive impairment in an urban community in China: a cross-sectional analysis of the Shanghai Aging Study. / 03.2015 / PubMed / Full text
  • Cognitive and neural signatures of the APOE E4 allele in mid-aged adults. / 07.2014 / PubMed / Full text
  • Mitochondrial DNA and traumatic brain injury. / 02.2014 / PubMed / Full text
  • The APOE ε4 allele in relation to brain white-matter microstructure in adulthood and aging. / 06.2014 / PubMed / Full text
  • Stress, race, and APOE: understanding the interplay of risk factors for changes in cognitive functioning. / 2014 / PubMed / Full text
  • Beta-amyloid associated differential effects of APOE ε4 on brain metabolism in cognitively normal elderly. / 10.2014 / PubMed / Full text
  • Apolipoprotein E and depressive symptoms: shared or independent routes to age-related cognitive decline? / 02.2014 / PubMed / Full text
  • Interaction of APOE genotype and testosterone on episodic memory in middle-aged men. / 07.2014 / PubMed / Full text
  • Sydney Memory and Ageing Study: an epidemiological cohort study of brain ageing and dementia. / 12.2013 / PubMed / Full text
  • Basal forebrain atrophy and cortical amyloid deposition in nondemented elderly subjects. / 10.2014 / PubMed / Full text
  • Interactive effects of apolipoprotein E4 and diabetes risk on later myelinating white matter regions in neurologically healthy older aged adults. / 05.2014 / PubMed / Full text

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  • Obesity is associated with early hip fracture risk in postmenopausal women: a 25-year follow-up. / 23.10.2020 / PubMed / Full text
  • ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells. / 09.2020 / PubMed / Full text
  • Effectiveness of adjuvant FOLFOX vs 5FU/LV in adults over age 65 with stage II and III colon cancer using a novel hybrid approach. / 12.2020 / PubMed / Full text
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  • Clinical and demographic parameters predict the progression from mild cognitive impairment to dementia in elderly patients. / 12.09.2020 / PubMed / Full text
  • Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women. / 01.12.2020 / PubMed / Full text
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  • Epigenetic age acceleration and clinical outcomes in gliomas. / 2020 / PubMed / Full text
  • Do Stairs Inhibit Seniors Who Live on Upper Floors From Going Out? / 10.2020 / PubMed / Full text
  • Age-specific acute changes in carotid-femoral pulse wave velocity with head-up tilt. / 07.07.2020 / PubMed / Full text
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  • Deterioration of bone microstructure by aging and menopause in Japanese healthy women: analysis by HR-pQCT. / 11.2020 / PubMed / Full text
  • Association between Low Protein Intake and Mortality in Patients with Type 2 Diabetes. / 01.06.2020 / PubMed / Full text
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  • Reduced cerebrovascular and cardioventilatory responses to intermittent hypoxia in elderly. / 01.2020 / PubMed / Full text
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  • Body weight at 10 years of age and change in body composition between 8 and 10 years of age were related to survival in a longitudinal study of 39 Labrador retriever dogs. / 09.09.2019 / PubMed / Full text
  • Dietary diversity offsets the adverse mortality risk among older indigenous Taiwanese. / 2019 / PubMed / Full text
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  • Bone Loss at the Hip and Subsequent Mortality in Older Men: The Osteoporotic Fractures in Men (MrOS) Study. / 08.2017 / PubMed / Full text
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  • Subjective life expectancy is a risk factor for perceived health status and mortality. / 02.10.2017 / PubMed / Full text
  • The effects of dexmedetomidine preconditioning on aged rat heart of ischaemia reperfusion injury. / 10.2017 / PubMed / Full text
  • Diabetes and Deficits in Cortical Bone Density, Microarchitecture, and Bone Size: Framingham HR-pQCT Study. / 01.2018 / PubMed / Full text
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  • Decline in effort capacity with age: Echocardiographic stress analysis in the elderly. / 12.2017 / PubMed / Full text
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  • Statins for Primary Prevention of Cardiovascular Events and Mortality in Older Men. / 11.2017 / PubMed / Full text
  • Galectin-3 and risk of ischaemic stroke: Reasons for Geographic and Racial Differences in Stroke cohort. / 12.2017 / PubMed / Full text
  • Sleep duration, mortality and the influence of age. / 10.2017 / PubMed / Full text
  • Comparison of yoga and walking-exercise on cardiac time intervals as a measure of cardiac function in elderly with increased pulse pressure. / 07-08.2017 / PubMed / Full text
  • Dietary acid load and renal function have varying effects on blood acid-base status and exercise performance across age and sex. / 12.2017 / PubMed / Full text
  • Elite Distance Runners: A 45-Year Follow-up. / 01.2018 / PubMed / Full text
  • Short-term water-based aerobic training promotes improvements in aerobic conditioning parameters of mature women. / 08.2017 / PubMed / Full text
  • Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study. / 03.2018 / PubMed / Full text
  • Impact of persistence and non-persistence in leisure time physical activity on coronary heart disease and all-cause mortality: The Copenhagen City Heart Study. / 10.2017 / PubMed / Full text
  • The Frequency-Dependent Aerobic Exercise Effects of Hypothalamic GABAergic Expression and Cardiovascular Functions in Aged Rats. / 2017 / PubMed / Full text
  • Frequency of frailty and its association with cognitive status and survival in older Chileans. / 2017 / PubMed / Full text
  • End-stage renal disease versus death in a Portuguese cohort of elderly patients: an approach using competing event analysis. / 10.2017 / PubMed / Full text
  • Reproducibility of 24-h heart rate variability in children. / 08.2017 / PubMed / Full text
  • Heritability of resting heart rate and association with mortality in middle-aged and elderly twins. / 01.2018 / PubMed / Full text
  • Diabetes mellitus: a risk factor for seizures in the elderly-a population-based study. / 09.2017 / PubMed / Full text
  • Age Modulates Physiological Responses during Fan Use under Extreme Heat and Humidity. / 11.2017 / PubMed / Full text
  • Dental Status and Compression of Life Expectancy with Disability. / 08.2017 / PubMed / Full text
  • Bone microstructure in men assessed by HR-pQCT: Associations with risk factors and differences between men with normal, low, and osteoporosis-range areal BMD. / 12.2016 / PubMed / Full text
  • Motor function and incident dementia: a systematic review and meta-analysis. / 01.09.2017 / PubMed / Full text
  • Effects of resistance training frequency on cardiorespiratory fitness in older men and women during intervention and follow-up. / 09.2017 / PubMed / Full text
  • Effect of High-Salt Diet on Age-Related High Blood Pressure and Hypothalamic Redox Signaling. / 2017 / PubMed / Full text
  • Cardiorespiratory responses and myocardial function within incremental exercise in healthy unmedicated older vs. young men and women. / 04.2018 / PubMed / Full text
  • Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies. / 08.2017 / PubMed / Full text
  • Changes in time spent walking and the risk of incident dementia in older Japanese people: the Ohsaki Cohort 2006 Study. / 01.09.2017 / PubMed / Full text
  • Buccal telomere length and its associations with cortisol, heart rate variability, heart rate, and blood pressure responses to an acute social evaluative stressor in college students. / 05.2017 / PubMed / Full text
  • Models describing metronidazole pharmacokinetics in relation to hemodynamics in turkeys. / 06.2017 / PubMed / Full text
  • Hearing Loss and Risk of Mild Cognitive Impairment and Dementia: Findings from the Singapore Longitudinal Ageing Study. / 2017 / PubMed / Full text
  • Assessment of effects of differences in trunk posture during Fowler's position on hemodynamics and cardiovascular regulation in older and younger subjects. / 2017 / PubMed / Full text
  • Age-related effects on markers of inflammation and cartilage metabolism in response to an intra-articular lipopolysaccharide challenge in horses. / 02.2017 / PubMed / Full text
  • Association of mortality and phase angle measured by different bioelectrical impedance analysis (BIA) devices. / 06.2018 / PubMed / Full text
  • Circulating Vitamin K Is Inversely Associated with Incident Cardiovascular Disease Risk among Those Treated for Hypertension in the Health, Aging, and Body Composition Study (Health ABC). / 05.2017 / PubMed / Full text
  • Recombinant cells in the lung increase with age via de novo recombination events and clonal expansion. / 04.2017 / PubMed / Full text
  • Caregiving, volunteering or both? Comparing effects on health and mortality using census-based records from almost 250,000 people aged 65 and over. / 01.09.2017 / PubMed / Full text
  • Sense of life worth living (ikigai) and incident functional disability in elderly Japanese: The Tsurugaya Project. / 04.2017 / PubMed / Full text
  • Effect of age and gender on serum periostin: Relationship to cortical measures, bone turnover and hormones. / 06.2017 / PubMed / Full text
  • Cross-sectional Versus Longitudinal Change in a Prospective HR-pQCT Study. / 07.2017 / PubMed / Full text
  • The association between frailty, the metabolic syndrome, and mortality over the lifespan. / 04.2017 / PubMed / Full text
  • Impacts of Dietary Phytochemicals in the Presence and Absence of Pesticides on Longevity of Honey Bees (Apis mellifera). / 14.02.2017 / PubMed / Full text
  • Complications during hospitalization and risk factors in elderly patients with hip fracture following integrated orthogeriatric treatment. / 04.2017 / PubMed / Full text
  • Alcoholic beverage preference and diabetes incidence across Europe: the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) project. / 05.2017 / PubMed / Full text
  • Social relations, depressive symptoms, and incident type 2 diabetes mellitus: The English Longitudinal Study of Ageing. / 04.2017 / PubMed / Full text
  • No increased risk of cardiovascular events in older adults initiating dipeptidyl peptidase-4 inhibitors vs therapeutic alternatives. / 07.2017 / PubMed / Full text
  • Arterial Pressure, Heart Rate, and Cerebral Hemodynamics Across the Adult Life Span. / 04.2017 / PubMed / Full text
  • Physical inactivity is a strong risk factor for stroke in the oldest old: Findings from a multi-ethnic population (the Northern Manhattan Study). / 02.2017 / PubMed / Full text
  • Cognitive Decline, Body Mass Index, and Waist Circumference in Community-Dwelling Elderly Participants. / 03.2017 / PubMed / Full text
  • Maximal heart rate declines linearly with age independent of cardiorespiratory fitness levels. / 06.2017 / PubMed / Full text
  • Age-Associated ALU Element Instability in White Blood Cells Is Linked to Lower Survival in Elderly Adults: A Preliminary Cohort Study. / 2017 / PubMed / Full text
  • Cortical porosity exhibits accelerated rate of change in peri- compared with post-menopausal women. / 04.2017 / PubMed / Full text
  • Aging impairs double-strand break repair by homologous recombination in Drosophila germ cells. / 04.2017 / PubMed / Full text
  • Age-related reference curves of volumetric bone density, structure, and biomechanical parameters adjusted for weight and height in a population of healthy women: an HR-pQCT study. / 04.2017 / PubMed / Full text
  • Cortical Bone Area Predicts Incident Fractures Independently of Areal Bone Mineral Density in Older Men. / 01.02.2017 / PubMed / Full text
  • The Power of Serum Uric Acid in Predicting Metabolic Syndrome Diminishes With Age in an Elderly Chinese Population. / 2016 / PubMed / Full text
  • Age- and Sex-Dependent Changes of Intra-articular Cortical and Trabecular Bone Structure and the Effects of Rheumatoid Arthritis. / 04.2017 / PubMed / Full text
  • Paradoxical delay of senescence upon depletion of BRCA2 in telomerase-deficient worms. / 10.2016 / PubMed / Full text
  • Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence. / 11.10.2016 / PubMed / Full text
  • Association of Age, Systolic Blood Pressure, and Heart Rate with Adult Morbidity and Mortality after Urgent Care Visits. / 09.2016 / PubMed / Full text
  • Characterization of Activity and Cardiovascular Responses During Surfing in Recreational Male Surfers Between the Ages of 18 and 75 Years Old. / 04.2017 / PubMed / Full text
  • Socioeconomic correlates of quality of life for non-Māori in advanced age: Te Puāwaitanga o Nga Tapuwae Kia ora Tonu. Life and Living in Advanced Age: a Cohort Study in New Zealand (LiLACS NZ). / 09.09.2016 / PubMed
  • The impacts of age and frailty on heart rate and sinoatrial node function. / 01.12.2016 / PubMed / Full text
  • Consequences of mating and predation risk for longevity in a freshwater snail: abstinence makes the heart beat longer. / 12.2016 / PubMed / Full text
  • Investigation of risk factors for mortality in aged guide dogs: A retrospective cohort study. / 15.09.2016 / PubMed / Full text
  • Age-Related Sensory Impairments and Risk of Cognitive Impairment. / 10.2016 / PubMed / Full text
  • Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. / 2016 / PubMed / Full text
  • Baseline, Time-Updated, and Cumulative HIV Care Metrics for Predicting Acute Myocardial Infarction and All-Cause Mortality. / 01.12.2016 / PubMed / Full text
  • Heart rate variability during sleep in children with autism spectrum disorder. / 12.2016 / PubMed / Full text
  • Aged rats show dominant modulation of lower frequency hippocampal theta rhythm during running. / 10.2016 / PubMed / Full text
  • Effect of floorball training on blood lipids, body composition, muscle strength, and functional capacity of elderly men. / 11.2017 / PubMed / Full text
  • The muscle quality index and mortality among males and females. / 09.2016 / PubMed / Full text
  • Nutrition and mortality in the elderly over 10 years of follow-up: the Three-City study. / 09.2016 / PubMed / Full text
  • Omega-3 polyunsaturated fatty acid supplementation attenuates blood pressure increase at onset of isometric handgrip exercise in healthy young and older humans. / 07.2016 / PubMed / Full text
  • Energy intake, energy required and mortality in an older population. / 12.2016 / PubMed / Full text
  • Dietary flavonoid intake and risk of incident depression in midlife and older women. / 09.2016 / PubMed / Full text
  • Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans. / 01.11.2016 / PubMed / Full text
  • SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. / 02.10.2016 / PubMed / Full text
  • Inflammatory Markers and the Risk of Hip and Vertebral Fractures in Men: the Osteoporotic Fractures in Men (MrOS). / 12.2016 / PubMed / Full text
  • Do BRCA1/2 mutation carriers have an earlier onset of natural menopause? / 08.2016 / PubMed / Full text
  • The pathophysiologic mechanisms associated with hypotensive susceptibility. / 08.2016 / PubMed / Full text
  • Association Between Mortality and Heritability of the Scale of Aging Vigor in Epidemiology. / 08.2016 / PubMed / Full text
  • Does cytomegalovirus infection contribute to socioeconomic disparities in all-cause mortality? / 09.2016 / PubMed / Full text
  • Independent effects of early-life experience and trait aggression on cardiovascular function. / 01.08.2016 / PubMed / Full text
  • Submaximal Exercise Systolic Blood Pressure and Heart Rate at 20 Years of Follow-up: Correlates in the Framingham Heart Study. / 27.05.2016 / PubMed / Full text
  • Parity and Oral Contraceptive Use in Relation to Ovarian Cancer Risk in Older Women. / 07.2016 / PubMed / Full text
  • Social participation and mortality: does social position in civic groups matter? / 12.05.2016 / PubMed / Full text
  • Decreased glomerular filtration rate estimated by 2009 CKD-EPI equation predicts mortality in older hip fracture population. / 07.2016 / PubMed / Full text
  • Greater Adherence to the Alternative Healthy Eating Index Is Associated with Lower Incidence of Physical Function Impairment in the Nurses' Health Study. / 07.2016 / PubMed / Full text
  • Cardiovascular Benefits of Endurance Training in Seniors: 40 is not too Late to Start. / 07.2016 / PubMed / Full text
  • Objectively Verified Parental Hip Fracture Is an Independent Risk Factor for Fracture: a Linkage Analysis of 478,792 Parents and 261,705 Offspring. / 09.2016 / PubMed / Full text
  • Maximum bite force at age 70 years predicts all-cause mortality during the following 13 years in Japanese men. / 08.2016 / PubMed / Full text
  • Frailty as a Predictor of Institutionalization Among Adults With Intellectual and Developmental Disabilities. / 04.2016 / PubMed / Full text
  • Recent trends in life expectancy for people with type 1 diabetes in Sweden. / 06.2016 / PubMed / Full text
  • A Global View on the Effects of Work on Health in Later Life. / 04.2016 / PubMed / Full text
  • Comparison of bioenergetics of walking during a multistage incremental shuttle walk test and a 6-min walk test in active older adults. / 04.2017 / PubMed / Full text
  • Effect of valsartan on cardiac senescence and apoptosis in a rat model of cardiotoxicity. / 06.2016 / PubMed / Full text
  • Frailty as a predictor of hospitalisation among community-dwelling older people: a systematic review and meta-analysis. / 07.2016 / PubMed / Full text
  • Reaction Time Measures Predict Incident Dementia in Community-Living Older Adults: The Sydney Memory and Ageing Study. / 03.2016 / PubMed / Full text
  • Quantitative Scheimpflug camera study of the lens density in healthy Turkish population. / 12.2016 / PubMed / Full text
  • Comparison of heart rate changes with ictal tachycardia seizures in adults and children. / 04.2016 / PubMed / Full text
  • The Influence of Age and Central Foveal Thickness on Foveal Zone Size in Healthy People. / 02.2016 / PubMed / Full text
  • Natural history of age-related lobular involution and impact on breast cancer risk. / 02.2016 / PubMed / Full text
  • Long-term Cognitive Trajectories and Mortality in Older Women. / 08.2016 / PubMed / Full text
  • Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study. / 03.2016 / PubMed / Full text
  • How are neuroticism and depression related to the psychophysiological stress response to acute stress in healthy older people? / 15.03.2016 / PubMed / Full text
  • A novel technique to investigate the effect of ageing on ventricular repolarization characteristics in healthy and LQTS subjects. / 08.2015 / PubMed / Full text
  • Age-dependent prognostic value of exercise capacity and derivation of fitness-associated biologic age. / 03.2016 / PubMed / Full text
  • Muscle Quality and Myosteatosis: Novel Associations With Mortality Risk: The Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study. / 01.01.2016 / PubMed / Full text
  • Long-term UVA eye irradiation causes decreased learning ability in mice. / 05.2016 / PubMed / Full text
  • Smoking status and life expectancy after acute myocardial infarction in the elderly. / 01.2016 / PubMed / Full text
  • Hypogonadism and Mortality in Aged Hospitalized Male Patients: A 5-Year Prospective Observational Study. / 11.2015 / PubMed / Full text
  • Social network typologies and mortality risk among older people in China, India, and Latin America: A 10/66 Dementia Research Group population-based cohort study. / 12.2015 / PubMed / Full text
  • Age-related changes in bone strength from HR-pQCT derived microarchitectural parameters with an emphasis on the role of cortical porosity. / 02.2016 / PubMed / Full text
  • Beta-Adrenergic Blockade Therapy for Autonomic Dysfunction is Less Effective for Elderly Patients with Heart Failure and Reduced Left Ventricular Ejection Fraction. / 2015 / PubMed / Full text
  • The Association of Reproductive Hormone Levels and All-Cause, Cancer, and Cardiovascular Disease Mortality in Men. / 12.2015 / PubMed / Full text
  • Advanced Age, High β-CTX Levels, and Impaired Renal Function are Independent Risk Factors for All-Cause One-Year Mortality in Hip Fracture Patients. / 01.2016 / PubMed / Full text
  • Aging augments renal vasoconstrictor response to orthostatic stress in humans. / 15.12.2015 / PubMed / Full text
  • The SIRT1 promoter polymorphic site rs12778366 increases IL-6 related human mortality in the prospective study "Treviso Longeva (TRELONG)". / 2015 / PubMed / Full text
  • Sleeve Gastrectomy Decreases Body Weight, Whole-Body Adiposity, and Blood Pressure Even in Aged Diet-Induced Obese Rats. / 07.2016 / PubMed / Full text
  • Associations of obesity and body fat distribution with incident atrial fibrillation in the biracial health aging and body composition cohort of older adults. / 09.2015 / PubMed / Full text
  • Food Habits, Lifestyle Factors and Mortality among Oldest Old Chinese: The Chinese Longitudinal Healthy Longevity Survey (CLHLS). / 09.09.2015 / PubMed / Full text
  • Age- and Gender-related Disparities in Primary Percutaneous Coronary Interventions for Acute ST-segment elevation Myocardial Infarction. / 2015 / PubMed / Full text
  • Functional measures, inflammatory markers and endothelin-1 as predictors of 360-day survival in centenarians. / 10.2015 / PubMed / Full text
  • Low-frequency oscillations in cerebrovascular and cardiovascular hemodynamics: Their interrelationships and the effect of age. / 11.2015 / PubMed / Full text
  • Testing a modified perceived exertion scale for Alzheimer's disease. / 03.2015 / PubMed / Full text
  • High Cardiorespiratory Fitness Levels Slow the Decline in Peak Heart Rate with Age. / 01.2016 / PubMed / Full text
  • Sex and age effects on cardiovascular autonomic function in healthy adults. / 10.2015 / PubMed / Full text
  • Role of endocortical contouring methods on precision of HR-pQCT-derived cortical micro-architecture in postmenopausal women and young adults. / 02.2016 / PubMed / Full text
  • History of previous bleeding and C-reactive protein improve assessment of bleeding risk in elderly patients (≥ 80 years) with myocardial infarction. / 11.2015 / PubMed / Full text
  • Use of serum albumin and activities of daily living to predict mortality in long-lived individuals over 95 years of age: a population-based study. / 08.2015 / PubMed / Full text
  • Pyridostigmine enhances atrial tachyarrhythmias in aging spontaneously hypertensive rats. / 10.2015 / PubMed / Full text
  • Low heel ultrasound parameters predict mortality in men: results from the European Male Ageing Study (EMAS). / 09.2015 / PubMed / Full text
  • Regulation of Cardiac Autonomic Nervous System Control across Frailty Statuses: A Systematic Review. / 2015 / PubMed / Full text
  • Anti-mullerian hormone (AMH) is associated with natural menopause in a population-based sample: The CARDIA Women's Study. / 08.2015 / PubMed / Full text
  • Dose-dependent effect of androgen deprivation therapy for localized prostate cancer on adverse cardiac events. / 08.2016 / PubMed / Full text
  • Ischemic heart disease, prescription of optimal medical therapy and geriatric syndromes in community-dwelling older men: A population-based study. / 01.08.2015 / PubMed / Full text
  • Gait characteristics and sensory abilities of older adults are modulated by gender. / 06.2015 / PubMed / Full text
  • Severity of depressive symptoms as a predictor of mortality: the English longitudinal study of ageing. / 10.2015 / PubMed / Full text
  • Higher Intake of Fruit, but Not Vegetables or Fiber, at Baseline Is Associated with Lower Risk of Becoming Overweight or Obese in Middle-Aged and Older Women of Normal BMI at Baseline. / 05.2015 / PubMed / Full text
  • Effect of a community intervention programme promoting social interactions on functional disability prevention for older adults: propensity score matching and instrumental variable analyses, JAGES Taketoyo study. / 09.2015 / PubMed / Full text
  • Comparison of cyclic and impact-based reference point indentation measurements in human cadaveric tibia. / 01.2018 / PubMed / Full text
  • Association of dialysis with the risks of cancers. / 2015 / PubMed / Full text
  • Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver. / 03.2015 / PubMed / Full text
  • Higher circulating adiponectin levels are associated with increased risk of atrial fibrillation in older adults. / 09.2015 / PubMed / Full text
  • Age-related changes in thirst, salt appetite, and arterial blood pressure in response to aldosterone-dexamethasone combination in rats. / 15.05.2015 / PubMed / Full text
  • Undertreatment of Men in Their Seventies with High-risk Nonmetastatic Prostate Cancer. / 07.2015 / PubMed / Full text
  • Anthropometric indices and dietary intake: prospective determinants of geriatric cognitive impairment? / 04.2013 / PubMed / Full text
  • 'Carriers of variant luteinizing hormone (V-LH) among 1593 Baltic men have significantly higher serum LH'. / 05.2015 / PubMed / Full text
  • Impact of living alone on institutionalization and mortality: a population-based longitudinal study. / 02.2016 / PubMed / Full text
  • [Normal values for high-resolution anorectal manometry in a healthy women: effects of age and maternity]. / 2014 / PubMed
  • A comparison of risperidone and haloperidol for the risk of ischemic stroke in the elderly: a propensity score-matched cohort analysis. / 08.2015 / PubMed / Full text
  • Inhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity. / 03.2015 / PubMed / Full text
  • Conservation of pro-longevity genes among mammals. / 03.2015 / PubMed / Full text
  • Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture risk in older adults: the Age, Gene/Environment Susceptibility Study. / 05.2015 / PubMed / Full text
  • Health related quality of life and perception of stigmatisation in adolescents living with sickle cell disease in Nigeria: A cross sectional study. / 07.2015 / PubMed / Full text
  • Bioidentical hormones, menopausal women, and the lure of the "natural" in U.S. anti-aging medicine. / 05.2015 / PubMed / Full text
  • Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. / 07.2015 / PubMed / Full text
  • Do Arterial Hemodynamic Parameters Predict Cognitive Decline Over a Period of 2 Years in Individuals Older Than 80 Years Living in Nursing Homes? The PARTAGE Study. / 01.07.2015 / PubMed / Full text
  • Providing instrumental social support is more beneficial to reduce mortality risk among the elderly with low educational level in Taiwan: a 12-year follow-up national longitudinal study. / 04.2015 / PubMed / Full text
  • Correlates and moderators of change in subjective memory and memory performance: findings from the health and retirement study. / 2015 / PubMed / Full text
  • Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging. / 2014 / PubMed / Full text
  • Resident health-related quality of life in Swiss nursing homes. / 07.2015 / PubMed / Full text
  • Multiple modes of assessment of gait are better than one to predict incident falls. / 05-06.2015 / PubMed / Full text
  • Social vulnerability and survival across levels of frailty in the Honolulu-Asia Aging Study. / 07.2015 / PubMed / Full text
  • Survival time of calves with positive BVD virus results born during the voluntary phase of the Irish eradication programme. / 01.05.2015 / PubMed / Full text
  • Physiological factors contributing to mobility loss over 9 years of follow-up—results from the InCHIANTI study. / 05.2015 / PubMed / Full text
  • Aspirin Has a Protective Effect Against Adverse Outcomes in Patients with Nonvariceal Upper Gastrointestinal Bleeding. / 07.2015 / PubMed / Full text
  • Spatial distribution of intracortical porosity varies across age and sex. / 06.2015 / PubMed / Full text
  • Older male physicians have lower risk of trochanteric but not cervical hip fractures. / 16.02.2015 / PubMed / Full text
  • Gender difference in diabetes-associated risk of first-ever and recurrent ischemic stroke. / 07.2015 / PubMed / Full text
  • Dose of jogging and long-term mortality: the Copenhagen City Heart Study. / 10.02.2015 / PubMed / Full text
  • Age-related differences in volumetric bone mineral density, microarchitecture, and bone strength of distal radius and tibia in Chinese women: a high-resolution pQCT reference database study. / 06.2015 / PubMed / Full text
  • Cardiac autonomic modulation in healthy elderly after different intensities of dynamic exercise. / 2015 / PubMed / Full text
  • Low-density lipoprotein cholesterol was inversely associated with 3-year all-cause mortality among Chinese oldest old: data from the Chinese Longitudinal Healthy Longevity Survey. / 03.2015 / PubMed / Full text
  • Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process. / 10.04.2015 / PubMed / Full text
  • Multimorbidity measures were poor predictors of adverse events in patients aged ≥80 years: a prospective cohort study. / 02.2015 / PubMed / Full text
  • Genetic relationship among reproductive traits in Nellore cattle. / 05.2015 / PubMed / Full text
  • Age-related differences when walking downhill on different sloped terrains. / 01.2015 / PubMed / Full text
  • HIV and aging: insights from the Asia Pacific HIV Observational Database (APHOD). / 03.2015 / PubMed / Full text
  • Obesity in the Context of Aging: Quality of Life Considerations. / 07.2015 / PubMed / Full text
  • Objective measures of activity level and mortality in older men. / 11.2014 / PubMed / Full text
  • The ROVIGO study (risk of vascular complications: impact of genetics in old people): protocol, study design, and preliminary results of the initial survey : cardiovascular epidemiology in the elderly. / 03.2015 / PubMed / Full text
  • Association between sleep duration and mortality is mediated by markers of inflammation and health in older adults: the Health, Aging and Body Composition Study. / 01.02.2015 / PubMed / Full text
  • Sarcopenia-related parameters and incident disability in older persons: results from the "invecchiare in Chianti" study. / 04.2015 / PubMed / Full text
  • Predicted maximal heart rate for upper body exercise testing. / 03.2016 / PubMed / Full text
  • Early life body mass trajectories and mortality in older age: findings from the Helsinki Birth Cohort Study. / 02.2015 / PubMed / Full text
  • Patient age and the prognosis of idiopathic membranous nephropathy. / 2014 / PubMed / Full text
  • Gender differences in survival in old age. / 12.2014 / PubMed / Full text
  • Long-term physical activity and risk of age-related cataract: a population-based prospective study of male and female cohorts. / 02.2015 / PubMed / Full text
  • Effects of body mass index, abdominal obesity, and type 2 diabetes on mortality in community-dwelling elderly in Sao Paulo, Brazil: analysis of prospective data from the SABE study. / 04.2015 / PubMed / Full text
  • All-cause and disease-specific mortality among male, former elite athletes: an average 50-year follow-up. / 07.2015 / PubMed / Full text
  • Characterization of metabolites determined by means of 1H HR MAS NMR in intervertebral disc degeneration. / 04.2015 / PubMed / Full text
  • The role of RecQ helicases in non-homologous end-joining. / 11-12.2014 / PubMed / Full text
  • Normal pediatric data for isovolumic acceleration at the lateral tricuspid valve annulus-a heart rate - dependent measure of right ventricular contractility. / 03.2015 / PubMed / Full text
  • Higher orthostatic heart rate predicts mortality: The Irish Longitudinal Study on Ageing (TILDA). / 04.2015 / PubMed / Full text
  • Aging and CaMKII alter intracellular Ca2 transients and heart rhythm in Drosophila melanogaster. / 2014 / PubMed / Full text
  • Do hassles mediate between life events and mortality in older men? Longitudinal findings from the VA Normative Aging Study. / 11.2014 / PubMed / Full text
  • Survival analysis of breast cancer subtypes in patients with spinal metastases. / 01.09.2014 / PubMed / Full text
  • Optimal management of colorectal liver metastases in older patients: a decision analysis. / 11.2014 / PubMed / Full text
  • Examining physiological responses across different driving maneuvers during an on-road driving task: a pilot study comparing older and younger drivers. / 2015 / PubMed / Full text
  • Rosa26-GFP direct repeat (RaDR-GFP) mice reveal tissue- and age-dependence of homologous recombination in mammals in vivo. / 06.2014 / PubMed / Full text
  • Association of total adiposity and computed tomographic measures of regional adiposity with incident cancer risk: a prospective population-based study of older adults. / 06.2014 / PubMed / Full text
  • Racial disparities in an aging population: the relationship between age and race in the management of African American men with high-risk prostate cancer. / 01.10.2014 / PubMed / Full text
  • Life expectancy following orbital exenteration. / 01.2015 / PubMed / Full text
  • Do age-disparate relationships drive HIV incidence in young women? Evidence from a population cohort in rural KwaZulu-Natal, South Africa. / 01.08.2014 / PubMed / Full text
  • Hippocampus and amygdala volumes in children and young adults at high-risk of schizophrenia: research synthesis. / 06.2014 / PubMed / Full text
  • Assessment of physical strain in younger and older subjects using heart rate and scalings of perceived exertion. / 2014 / PubMed / Full text
  • Episodic ozone exposure in adult and senescent Brown Norway rats: acute and delayed effect on heart rate, core temperature and motor activity. / 06.2014 / PubMed / Full text
  • Characterizing microarchitectural changes at the distal radius and tibia in postmenopausal women using HR-pQCT. / 08.2014 / PubMed / Full text
  • Individual and spousal education, mortality and life expectancy in Switzerland: a national cohort study. / 09.2014 / PubMed / Full text
  • Association Between 6-Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease. / 06.2014 / PubMed / Full text
  • Sleep duration and incidence of lung cancer in ageing men. / 31.03.2014 / PubMed / Full text
  • Effect of aging on carotid baroreflex control of blood pressure and leg vascular conductance in women. / 15.05.2014 / PubMed / Full text
  • Physical activity in older men: longitudinal associations with inflammatory and hemostatic biomarkers, N-terminal pro-brain natriuretic peptide, and onset of coronary heart disease and mortality. / 04.2014 / PubMed / Full text
  • Predicting all-cause and cause-specific mortality by static and dynamic measurements of allostatic load: a 10-year population-based cohort study in Taiwan. / 07.2014 / PubMed / Full text
  • Contribution of Alzheimer disease to mortality in the United States. / 25.03.2014 / PubMed / Full text
  • Physiological characteristics of an aging Olympic athlete. / 11.2014 / PubMed / Full text
  • Association of sex hormones, aging, and atrial fibrillation in men: the Framingham Heart Study. / 04.2014 / PubMed / Full text
  • A pooled analysis of waist circumference and mortality in 650,000 adults. / 03.2014 / PubMed / Full text
  • Hearing loss may be a non-motor feature of Parkinson's disease in older people in Taiwan. / 05.2014 / PubMed / Full text
  • Cognitive performance and functional status are the major factors predicting survival of centenarians in Poland. / 10.2014 / PubMed / Full text
  • Vitamin D deficiency in elderly people in Swedish nursing homes is associated with increased mortality. / 05.2014 / PubMed / Full text
  • Association between sex steroid levels and bone microarchitecture in men: the STRAMBO study. / 04.2014 / PubMed / Full text
  • Metabolomics signature improves the prediction of cardiovascular events in elderly subjects. / 02.2014 / PubMed / Full text
  • Mortality in systemic sclerosis: lessons learned from population-based and observational cohort studies. / 03.2014 / PubMed / Full text
  • BMI and all-cause mortality in older adults: a meta-analysis. / 04.2014 / PubMed / Full text
  • Gender-specific associations between physical functioning, bone quality, and fracture risk in older people. / 05.2014 / PubMed / Full text
  • Late-onset hypogonadism and mortality in aging men. / 04.2014 / PubMed / Full text
  • Effect of light-dark changes on the locomotor activity in open field in adult rats and opossums. / 11.2013 / PubMed / Full text
  • Differential contribution of afferent and central pathways to the development of baroreflex dysfunction in chronic kidney disease. / 04.2014 / PubMed / Full text
  • Association of 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D and parathyroid hormone with mortality among middle-aged and older European men. / 07.2014 / PubMed / Full text
  • Physiological response to a breed evaluation field test in Icelandic horses. / 03.2014 / PubMed / Full text

SIRT1Править

  • Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats. / 03.12.2020 / PubMed / Full text
  • Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective. / 05.12.2020 / PubMed / Full text
  • Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells. / 10.2020 / PubMed / Full text
  • SIRT1 Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence. / 04.11.2020 / PubMed / Full text
  • Histone Deacetylase SIRT1, Smooth Muscle Cell Function, and Vascular Diseases. / 2020 / PubMed / Full text
  • 6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing SIRT1 and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation. / 27.10.2020 / PubMed / Full text
  • Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through SIRT1 activation and AKT/mTOR pathway inhibition. / 30.09.2020 / PubMed / Full text
  • SIRT1 Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence. / 2020 / PubMed / Full text
  • The Role of Sirtuins in Kidney Diseases. / 12.09.2020 / PubMed / Full text
  • The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. / 11.2020 / PubMed / Full text
  • Virus-Induced Asthma Exacerbations: SIRT1 Targeted Approach. / 13.08.2020 / PubMed / Full text
  • Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts. / 12.2020 / PubMed / Full text
  • Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/SIRT1-FOXA3-Beclin1 pathway. / 01.10.2020 / PubMed / Full text
  • Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence. / 08.2020 / PubMed / Full text
  • Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of SIRT1 in Human Dermal Fibroblasts. / 01.07.2020 / PubMed / Full text
  • SRT1720-induced activation of SIRT1 alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485. / 07.2020 / PubMed / Full text
  • miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss. / 2020 / PubMed / Full text
  • Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes. / 01-12.2020 / PubMed / Full text
  • Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats. / 10.2020 / PubMed / Full text
  • The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis. / 2020 / PubMed / Full text
  • Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells. / 2020 / PubMed / Full text
  • Spatiotemporal gating of SIRT1 functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia. / 24.03.2020 / PubMed / Full text
  • Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of SIRT1. / 2020 / PubMed / Full text
  • SIRT1 and aging related signaling pathways. / 04.2020 / PubMed / Full text
  • Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of SIRT1 signaling. / 01.05.2020 / PubMed / Full text
  • Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. / 04.2020 / PubMed / Full text
  • Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells. / 01.05.2020 / PubMed / Full text
  • Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal SIRT1 Levels Improving Cognition in Aged Rats. / 26.01.2020 / PubMed / Full text
  • Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating SIRT1. / 01.2020 / PubMed / Full text
  • Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence. / 06-07.2020 / PubMed / Full text
  • Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1. / 23.12.2019 / PubMed / Full text
  • The protective role of omentin-1 in IL-1β-induced chondrocyte senescence. / 12.2020 / PubMed / Full text
  • The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD Level Is Lower than the Sirtuin-Saturating Concentrations. / 24.12.2019 / PubMed / Full text
  • Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells. / 06.2020 / PubMed / Full text
  • Central nervous system SIRT1 expression is required for cued and contextual fear conditioning memory responses in aging mice. / 23.09.2019 / PubMed / Full text
  • Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education. / 10.2019 / PubMed
  • CO ameliorates endothelial senescence induced by 5-fluorouracil through SIRT1 activation. / 30.11.2019 / PubMed / Full text
  • Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating SIRT1 expression. / 20.10.2019 / PubMed / Full text
  • The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging. / 2019 / PubMed / Full text
  • Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. / 03.2020 / PubMed / Full text
  • Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure. / 13.02.2020 / PubMed / Full text
  • Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of SIRT1. / 2019 / PubMed / Full text
  • Activation of the miR-34a-Mediated SIRT1/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice. / 10.2019 / PubMed / Full text
  • [Ginsenoside Rg_1 induces leukemia stem cell senescence via SIRT1/TSC_2 signal axis]. / 06.2019 / PubMed / Full text
  • miR-23b-3p regulates apoptosis and autophagy via suppressing SIRT1 in lens epithelial cells. / 12.2019 / PubMed / Full text
  • Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
  • Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. / 08.2019 / PubMed / Full text
  • Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence. / 01.10.2019 / PubMed / Full text
  • Involvement of [i]microRNA-34a[/i] in Age-Related Susceptibility to Oxidative Stress in ARPE-19 Cells by Targeting the Silent Mating Type Information Regulation 2 Homolog 1/p66shc Pathway: Implications for Age-Related Macular Degeneration. / 2019 / PubMed / Full text
  • GPR39 agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence. / 12.2019 / PubMed / Full text
  • Rational design of novel sirtuin 1 activators via structure-activity insights from application of QSAR modeling. / 2019 / PubMed / Full text
  • Metformin prevents murine ovarian aging. / 10.06.2019 / PubMed / Full text
  • Time-restricted feeding delays the emergence of the age-associated, neoplastic-prone tissue landscape. / 12.06.2019 / PubMed / Full text
  • Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway. / 10.06.2019 / PubMed / Full text
  • SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy. / 08.2019 / PubMed / Full text
  • Transcriptome analysis revealed potential mechanisms of differences in physiological stress responses between caged male and female magpies. / 03.06.2019 / PubMed / Full text
  • Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. / 10.2019 / PubMed / Full text
  • Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models. / 02.2019 / PubMed / Full text
  • Molecular and Cellular Characterization of SIRT1 Allosteric Activators. / 2019 / PubMed / Full text
  • Total flavonoids from the Carya cathayensis Sarg. leaves inhibit HUVEC senescence through the miR-34a/SIRT1 pathway. / 10.2019 / PubMed / Full text
  • Impaired SIRT1 activity leads to diminution in glomerular endowment without accelerating age-associated GFR decline. / 05.2019 / PubMed / Full text
  • Estrogen-SIRT1 Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis. / 01.01.2020 / PubMed / Full text
  • Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri. / 09.2019 / PubMed / Full text
  • Protective effect of vildagliptin on TNF-α-induced chondrocyte senescence. / 07.2019 / PubMed / Full text
  • Polymorphism rs7895833 in the SIRT1 gene and its association with dyslipidaemia in the elderly. / 07-08.2019 / PubMed / Full text
  • Modulation of miR-34a/SIRT1 signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis. / 07.2019 / PubMed / Full text
  • Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow. / 18.04.2019 / PubMed / Full text
  • Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom [i]Cordyceps militaris[/i] Linn., Ameliorates Age-Related Testicular Dysfunction in Rats. / 23.04.2019 / PubMed / Full text
  • The resistant effect of SIRT1 in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway. / 31.05.2019 / PubMed / Full text
  • Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. / 2019 / PubMed / Full text
  • The role of SIRT1 in neuroinflammation and cognitive dysfunction in aged rats after anesthesia and surgery. / 2019 / PubMed / Full text
  • NAD supplementation rejuvenates aged gut adult stem cells. / 06.2019 / PubMed / Full text
  • NMNAT2-mediated NAD generation is essential for quality control of aged oocytes. / 06.2019 / PubMed / Full text
  • Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure. / 07.2019 / PubMed / Full text
  • Drugs targeting SIRT1, a new generation of therapeutics for osteoporosis and other bone related disorders? / 05.2019 / PubMed / Full text
  • Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks. / 11.03.2019 / PubMed / Full text
  • Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions. / 04.2019 / PubMed / Full text
  • Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson's disease. / 04.02.2019 / PubMed / Full text
  • Bone Marrow Mesenchymal Stem Cells-Derived Exosomal MiR-29b-3p Regulates Aging-Associated Insulin Resistance. / 26.02.2019 / PubMed / Full text
  • Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats. / 02.2019 / PubMed / Full text
  • Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease. / 05.2019 / PubMed / Full text
  • Generation of a novel model of primary human cell senescence through Tenovin-6 mediated inhibition of sirtuins. / 06.2019 / PubMed / Full text
  • Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. / 04.2019 / PubMed / Full text
  • Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. / 23.01.2019 / PubMed / Full text
  • Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation. / 2018 / PubMed / Full text
  • NKT-like cells reveal higher than T lymphocytes expression of cellular protective proteins HSP70 and SOD2 and comparably increased expression of SIRT1 in the oldest seniors. / 2018 / PubMed / Full text
  • Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway. / 04.2019 / PubMed / Full text
  • Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats. / 23.12.2018 / PubMed / Full text
  • Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation. / 2018 / PubMed / Full text
  • Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice. / 15.04.2019 / PubMed / Full text
  • CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2. / 2018 / PubMed / Full text
  • Amentoflavone Induces Autophagy and Modulates p53. / 04.2019 / PubMed / Full text
  • Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells. / 03.2019 / PubMed / Full text
  • Sirtuins: Developing Innovative Treatments for Aged-Related Memory Loss and Alzheimer's Disease. / 2018 / PubMed / Full text
  • N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation. / 01.2019 / PubMed / Full text
  • Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice. / 20.11.2018 / PubMed / Full text
  • Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation. / 2018 / PubMed / Full text
  • Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and [i]C. elegans[/i]. / 20.11.2018 / PubMed / Full text
  • Sirtuins and NAD in the Development and Treatment of Metabolic and Cardiovascular Diseases. / 14.09.2018 / PubMed / Full text
  • SIRT1 deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis. / 12.2018 / PubMed / Full text
  • Prevention of Senescence in Vasculature Through Quiescence. / 10.2018 / PubMed / Full text
  • Melatonin and inflammation-Story of a double-edged blade. / 11.2018 / PubMed / Full text
  • ALDH2 mediates the dose-response protection of chronic ethanol against endothelial senescence through SIRT1/p53 pathway. / 12.10.2018 / PubMed / Full text
  • Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats. / 08.2018 / PubMed / Full text
  • Endothelial SIRT1 prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells. / 01.03.2019 / PubMed / Full text
  • Effects of Ginsenoside Rg3 on fatigue resistance and SIRT1 in aged rats. / 01.11.2018 / PubMed / Full text
  • PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD levels and increasing SIRT1 activity. / 23.08.2018 / PubMed / Full text
  • Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing SIRT1 and SIRT3 expression. / 10.2018 / PubMed / Full text
  • Liver regeneration in aged mice: new insights. / 28.08.2018 / PubMed / Full text
  • Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit's Heart and Liver. / 2018 / PubMed / Full text
  • Defect of SIRT1-FoxO3a axis is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated cellular senescence and nematode aging. / 04.2019 / PubMed / Full text
  • Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls. / 10.2018 / PubMed / Full text
  • Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes. / 01.05.2019 / PubMed / Full text
  • PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis. / 07.08.2018 / PubMed / Full text
  • Effect of oral appliance on circulating leukocyte telomere length and SIRT1 in obstructive sleep apnea. / 03.2019 / PubMed / Full text
  • miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating SIRT1 (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase). / 09.2018 / PubMed / Full text
  • A SIRT1-centered circuitry regulates breast cancer stemness and metastasis. / 12.2018 / PubMed / Full text
  • Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/SIRT1 signaling pathway. / 06.2018 / PubMed / Full text
  • Sirtuin 1 and Alzheimer's disease: An up-to-date review. / 10.2018 / PubMed / Full text
  • CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans. / 10.2018 / PubMed / Full text
  • Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-SIRT1-eNOS pathway. / 09.2018 / PubMed / Full text
  • Serum containing Buyang Huanwu decoction prevents age-associated migration and invasion of human vascular smooth muscle cells by up regulating SIRT1 expression. / 17.07.2018 / PubMed / Full text
  • Role of accelerated aging in limb muscle wasting of patients with COPD. / 2018 / PubMed / Full text
  • Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells. / 15.09.2018 / PubMed / Full text
  • Mesenchymal stem cells confer resistance to doxorubicin-induced cardiac senescence by inhibiting microRNA-34a. / 06.2018 / PubMed / Full text
  • The circadian clock in adult neural stem cell maintenance. / 02.2019 / PubMed / Full text
  • Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri. / 09.2018 / PubMed / Full text
  • Loss of NAMPT in aging retinal pigment epithelium reduces NAD availability and promotes cellular senescence. / 12.06.2018 / PubMed / Full text
  • Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes. / 06.2018 / PubMed / Full text
  • SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease. / 31.05.2018 / PubMed / Full text
  • Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence. / 09.2018 / PubMed / Full text
  • Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial Function. / 09.2018 / PubMed / Full text
  • Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats. / 2018 / PubMed / Full text
  • SIRT1 reverses senescence via enhancing autophagy and attenuates oxidative stress-induced apoptosis through promoting p53 degradation. / 01.10.2018 / PubMed / Full text
  • Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers. / 08.2018 / PubMed / Full text
  • Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition. / 07.2018 / PubMed / Full text
  • Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of SIRT1. / 2017 / PubMed / Full text
  • Role of hypothalamus in aging and its underlying cellular mechanisms. / 01.2019 / PubMed / Full text
  • The variable role of SIRT1 in the maintenance and differentiation of mesenchymal stem cells. / 04.2018 / PubMed / Full text
  • Sirtuins in Renal Health and Disease. / 07.2018 / PubMed / Full text
  • Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, SIRT1, SIRT3, and VEGF in the Substantia Nigra. / 10.11.2018 / PubMed / Full text
  • MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells. / 03.04.2018 / PubMed / Full text
  • Natural products with anti-aging potential: Affected targets and molecular mechanisms. / 01.11.2018 / PubMed / Full text
  • [Effect of microRNA-34a/SIRT1/p53 signal pathway on notoginsenoside R₁ delaying vascular endothelial cell senescence]. / 02.2018 / PubMed / Full text
  • SIRT1 and microRNAs: The role in breast, lung and prostate cancers. / 01.06.2018 / PubMed / Full text
  • Leukotriene D4 induces cellular senescence in osteoblasts. / 05.2018 / PubMed / Full text
  • Impairment of an Endothelial NAD -H S Signaling Network Is a Reversible Cause of Vascular Aging. / 22.03.2018 / PubMed / Full text
  • Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas. / 08.2018 / PubMed / Full text
  • Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. / 06.03.2018 / PubMed / Full text
  • Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming. / 05.2018 / PubMed / Full text
  • HGF and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the SIRT1/FOXO1 Signaling Pathway. / 2018 / PubMed / Full text
  • The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system. / 03.2018 / PubMed / Full text
  • Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. / 04.2018 / PubMed / Full text
  • Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes. / 03.2018 / PubMed / Full text
  • Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress. / 20.02.2018 / PubMed / Full text
  • Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury. / 11.01.2018 / PubMed / Full text
  • Acetylshikonin from Zicao attenuates cognitive impairment and hippocampus senescence in d-galactose-induced aging mouse model via upregulating the expression of SIRT1. / 03.2018 / PubMed / Full text
  • Dexamethasone downregulates SIRT1 and IL6 and upregulates EDN1 genes in stem cells derived from gingivae via the AGE/RAGE pathway. / 03.2018 / PubMed / Full text
  • Sirtuins in Brain Aging and Neurological Disorders. / 2017 / PubMed / Full text
  • [Aging-related change of erectile function and the expression of SIRT1]. / 12.2016 / PubMed
  • Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans. / 2017 / PubMed / Full text
  • Maternal aging affects oocyte resilience to carbonyl cyanide-m-chlorophenylhydrazone -induced mitochondrial dysfunction in cows. / 2017 / PubMed / Full text
  • Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating SIRT1 activity and antioxidant gene expression in mouse cells. / 12.2017 / PubMed / Full text
  • Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™). / 04.2018 / PubMed / Full text
  • Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through SIRT1. / 2017 / PubMed / Full text
  • Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating SIRT1-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation. / 14.11.2017 / PubMed / Full text
  • Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice. / 13.10.2017 / PubMed / Full text
  • O-GlcNAcylation of SIRT1 enhances its deacetylase activity and promotes cytoprotection under stress. / 14.11.2017 / PubMed / Full text
  • Aging as an Epigenetic Phenomenon. / 10.2017 / PubMed / Full text
  • MeCP2 mediated dysfunction in senescent EPCs. / 03.10.2017 / PubMed / Full text
  • Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. / 01.2018 / PubMed / Full text
  • A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction. / 12.09.2017 / PubMed / Full text
  • Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence. / 17.10.2017 / PubMed / Full text
  • Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts. / 28.12.2017 / PubMed / Full text
  • Blocking SIRT1 inhibits cell proliferation and promotes aging through the PI3K/AKT pathway. / 01.12.2017 / PubMed / Full text
  • SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis. / 2017 / PubMed / Full text
  • [Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell]. / 02.2017 / PubMed / Full text
  • SIRT1 is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity. / 05.02.2018 / PubMed / Full text
  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
  • The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway. / 11.2017 / PubMed / Full text
  • Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats. / 03.2018 / PubMed / Full text
  • Aquatide Activation of SIRT1 Reduces Cellular Senescence through a SIRT1-FOXO1-Autophagy Axis. / 01.09.2017 / PubMed / Full text
  • Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3. / 20.10.2017 / PubMed / Full text
  • Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging. / 10.08.2017 / PubMed / Full text
  • High glucose and free fatty acids induce endothelial progenitor cell senescence via PGC-1α/SIRT1 signaling pathway. / 10.2017 / PubMed / Full text
  • Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. / 2017 / PubMed / Full text
  • Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway. / 01.2018 / PubMed / Full text
  • Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression. / 2017 / PubMed / Full text
  • Inflammation, Stem Cells, and the Aging Hypothalamus. / 08.2017 / PubMed / Full text
  • Myricetin improves endurance capacity and mitochondrial density by activating SIRT1 and PGC-1α. / 24.07.2017 / PubMed / Full text
  • Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer. / 2017 / PubMed / Full text
  • The emerging role of alternative splicing in senescence and aging. / 10.2017 / PubMed / Full text
  • miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans. / 08.2017 / PubMed / Full text
  • Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells. / 01.2018 / PubMed / Full text
  • SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection. / 10.03.2018 / PubMed / Full text
  • Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging. / 30.01.2018 / PubMed / Full text
  • Reduction in podocyte SIRT1 accelerates kidney injury in aging mice. / 01.09.2017 / PubMed / Full text
  • Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs. / 12.06.2017 / PubMed / Full text
  • Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers. / 2018 / PubMed / Full text
  • The NAD /PARP1/SIRT1 Axis in Aging. / 06.2017 / PubMed / Full text
  • Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota. / 09.2017 / PubMed / Full text
  • Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-SIRT1 pathway. / 08.2017 / PubMed / Full text
  • Bushen-Yizhi formula ameliorates cognitive dysfunction through SIRT1/ER stress pathway in SAMP8 mice. / 25.07.2017 / PubMed / Full text
  • Caveolin-1 deficiency induces premature senescence with mitochondrial dysfunction. / 08.2017 / PubMed / Full text
  • Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-FOXO1 pathway. / 2017 / PubMed / Full text
  • Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing. / 02.2018 / PubMed / Full text
  • Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats. / 08.2017 / PubMed / Full text
  • Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment. / 30.05.2017 / PubMed / Full text
  • During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent. / 08.2017 / PubMed / Full text
  • Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. / 01.06.2017 / PubMed / Full text
  • Regulation of stem cell aging by SIRT1 - Linking metabolic signaling to epigenetic modifications. / 05.11.2017 / PubMed / Full text
  • Ampelopsin attenuates the atrophy of skeletal muscle from d-gal-induced aging rats through activating AMPK/SIRT1/PGC-1α signaling cascade. / 06.2017 / PubMed / Full text
  • SIRT1 Polymorphisms and Serum-Induced SIRT1 Protein Expression in Aging and Frailty: The CHAMP Study. / 01.07.2017 / PubMed / Full text
  • Melatonin reverses H O -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB. / 08.2017 / PubMed / Full text
  • Alkylresorcinols activate SIRT1 and delay ageing in Drosophila melanogaster. / 02.03.2017 / PubMed / Full text
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|title=Tat-Mediated Induction of miRs-34a