Aging genes 80-89

AR[править]

Mechanisms of Androgen Receptor Agonist- and Antagonist-Mediated Cellular Senescence in Prostate Cancer. / 08.07.2020 / PubMed / Full text
Interleukin-23 Represses the Level of Cell Senescence Induced by the Androgen Receptor Antagonists Enzalutamide and Darolutamide in Castration-Resistant Prostate Cancer Cells. / 08.2020 / PubMed / Full text
A Landscape of Murine Long Non-Coding RNAs Reveals the Leading Transcriptome Alterations in Adipose Tissue during Aging. / 26.05.2020 / PubMed / Full text
Senolytic compounds control a distinct fate of androgen receptor agonist- and antagonist-induced cellular senescent LNCaP prostate cancer cells. / 2020 / PubMed / Full text
Accelerated aging of rice by controlled microwave treatment. / 18.04.2020 / PubMed / Full text
Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice. / 01.04.2020 / PubMed / Full text
A jaboticaba extract prevents prostatic damage associated with aging and high-fat diet intake. / 26.02.2020 / PubMed / Full text
TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands. / 26.11.2019 / PubMed / Full text
Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip. / 10.2019 / PubMed / Full text
Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging. / 05.09.2019 / PubMed / Full text
Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing. / 18.07.2019 / PubMed / Full text
Enhanced beta-1 adrenergic receptor responsiveness in coronary arterioles following intravenous stromal vascular fraction therapy in aged rats. / 11.07.2019 / PubMed / Full text
Older Adults Exhibit Greater Visual Cortex Inhibition and Reduced Visual Cortex Plasticity Compared to Younger Adults. / 2019 / PubMed / Full text
Loss of Prefrontal Cortical Higher Cognition with Uncontrollable Stress: Molecular Mechanisms, Changes with Age, and Relevance to Treatment. / 17.05.2019 / PubMed / Full text
Study on neuroendocrine-immune function of Phenylethanoid Glycosides of Desertliving Cistanche herb in perimenopausal rat model. / 28.06.2019 / PubMed / Full text
Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model. / 06.2019 / PubMed / Full text
Androgens Ameliorate Impaired Ischemia-Induced Neovascularization Due to Aging in Male Mice. / 01.05.2019 / PubMed / Full text
Halogen-substituted anthranilic acid derivatives provide a novel chemical platform for androgen receptor antagonists. / 04.2019 / PubMed / Full text
ERK mediated survival signaling is dependent on the Gq-G-protein coupled receptor type and subcellular localization in adult cardiac myocytes. / 02.2019 / PubMed / Full text
Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue. / 02.2019 / PubMed / Full text
Androgen Receptor in Neurons Slows Age-Related Cortical Thinning in Male Mice. / 03.2019 / PubMed / Full text
The presbycardia phenotype: Cardiac remodeling and valvular degeneration in nonagenarians. / 12.2018 / PubMed / Full text
The androgen receptor is required for maintenance of bone mass in adult male mice. / 05.01.2019 / PubMed / Full text
Sympathetic neurotransmission in spleens from aging Brown-Norway rats subjected to reduced sympathetic tone. / 15.11.2018 / PubMed / Full text
Assessment of the Aging of the Brown Adipose Tissue by F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna . / 2018 / PubMed / Full text
Staging of amyloid β, t-tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses. / 2018 / PubMed / Full text
Aging of human alpha rhythm. / 09.2018 / PubMed / Full text
Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. / 01.08.2018 / PubMed / Full text
Dexmedetomidine attenuates renal fibrosis via α2-adrenergic receptor-dependent inhibition of cellular senescence after renal ischemia/reperfusion. / 15.08.2018 / PubMed / Full text
Cross talk between androgen and Wnt signaling potentially contributes to age-related skeletal muscle atrophy in rats. / 01.08.2018 / PubMed / Full text
Increase in random component of heart rate variability coinciding with developmental and degenerative stages of life. / 25.05.2018 / PubMed / Full text
Relationship between morphological development and sex hormone receptor expression of mammary glands with age in male rats. / 30.07.2018 / PubMed / Full text
Altered expression of hepatic β-adrenergic receptors in aging rats: implications for age-related metabolic dysfunction in liver. / 01.04.2018 / PubMed / Full text
Reproductive aging in male dogs: The epididymal sperm defects and expression of androgen receptor in reproductive tissues. / 01.03.2018 / PubMed / Full text
Iron status and oxidative stress in the aged rabbit heart. / 01.2018 / PubMed / Full text
Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. / 01.2018 / PubMed / Full text
Impact of HPV vaccination: health gains in the Italian female population. / 29.09.2017 / PubMed / Full text
The prevalence and progression of mild cognitive impairment among clinic and community populations: a systematic review and meta-analysis. / 10.2017 / PubMed / Full text
Age-related changes in sexual function and steroid-hormone receptors in the medial preoptic area of male rats. / 11.2017 / PubMed / Full text
Amalaki rasayana, a traditional Indian drug enhances cardiac mitochondrial and contractile functions and improves cardiac function in rats with hypertrophy. / 17.08.2017 / PubMed / Full text
The biological and clinical advances of androgen receptor function in age-related diseases and cancer [Review]. / 28.10.2017 / PubMed / Full text
Local Allergic Rhinitis in Adult Patients with Chronic Nasal Symptoms. / 2017 / PubMed / Full text
Effect of Suo Quan Wan on the bladder function of aging rats based on the β-adrenoceptor. / 06.2017 / PubMed / Full text
Effect of early life physical growth on midlife vertebral dimensions - The Northern Finland Birth Cohort 1966 study. / 08.2017 / PubMed / Full text
Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate. / 09.05.2017 / PubMed / Full text
Gonad-related factors promote muscle performance gain during postnatal development in male and female mice. / 01.07.2017 / PubMed / Full text
Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain. / 01.04.2018 / PubMed / Full text
Glutathione metabolic status in the aged rabbit aorta. / 05.2017 / PubMed / Full text
The link between vascular dysfunction, bladder ischemia, and aging bladder dysfunction. / 01.2017 / PubMed / Full text
Expression of β1- and β2-adrenergic receptors in the lungs and changes in the levels of corresponding autoantibodies in an aged rat model of heart failure. / 12.2016 / PubMed / Full text
Anabolic resistance assessed by oral stable isotope ingestion following bed rest in young and older adult volunteers: Relationships with changes in muscle mass. / 10.2017 / PubMed / Full text
ADP-Induced Ca Signaling and Proliferation of Rat Ventricular Myofibroblasts Depend on Phospholipase C-Linked TRP Channels Activation Within Lipid Rafts. / 06.2017 / PubMed / Full text
Structural and Histochemical Alterations in the Aortic Valves of Elderly Patients: A Comparative Study of Aortic Stenosis, Aortic Regurgitation, and Normal Valves. / 2016 / PubMed / Full text
Preventive effects of dexmedetomidine on the development of cognitive dysfunction following systemic inflammation in aged rats. / 02.2017 / PubMed / Full text
Autosomal recessive brachyolmia: early radiological findings. / 11.2016 / PubMed / Full text
Morphological and molecular aspects of immobilization-induced muscle atrophy in rats at different stages of postnatal development: the role of autophagy. / 01.09.2016 / PubMed / Full text
The Long-Term Outcome of Boys With Partial Androgen Insensitivity Syndrome and a Mutation in the Androgen Receptor Gene. / 11.2016 / PubMed / Full text
Exacerbated cardiac fibrosis induced by β-adrenergic activation in old mice due to decreased AMPK activity. / 11.2016 / PubMed / Full text
The activation of OR51E1 causes growth suppression of human prostate cancer cells. / 26.07.2016 / PubMed / Full text
Role of androgens in dhea-induced rack1 expression and cytokine modulation in monocytes. / 2016 / PubMed / Full text
Aging up-regulates ARA55 in stromal cells, inducing androgen-mediated prostate cancer cell proliferation and migration. / 06.2016 / PubMed / Full text
Serum allergen-specific IgE, allergic rhinitis severity, and age. / 09.2016 / PubMed / Full text
The tumor suppressor ING1b is a novel corepressor for the androgen receptor and induces cellular senescence in prostate cancer cells. / 06.2016 / PubMed / Full text
β2-Adrenergic receptor ablation modulates hepatic lipid accumulation and glucose tolerance in aging mice. / 06.2016 / PubMed / Full text
Pubertal exposure to ethinylestradiol promotes different effects on the morphology of the prostate of the male and female gerbil during aging. / 02.2017 / PubMed / Full text
Changes in rat testis morphology and androgen receptor expression around the age of puberty. / 05.2016 / PubMed / Full text
Prenatal exposure to ethinylestradiol alters the morphologic patterns and increases the predisposition for prostatic lesions in male and female gerbils during ageing. / 02.2016 / PubMed / Full text
Testosterone enables growth and hypertrophy in fusion impaired myoblasts that display myotube atrophy: deciphering the role of androgen and IGF-I receptors. / 06.2016 / PubMed / Full text
The interaction of serum testosterone levels and androgen receptor CAG repeat polymorphism on the risk of erectile dysfunction in aging Taiwanese men. / 09.2015 / PubMed / Full text
Developing a DNA methylation assay for human age prediction in blood and bloodstain. / 07.2015 / PubMed / Full text
Suppression of induced but not developmental apoptosis in Drosophila by Ayurvedic Amalaki Rasayana and Rasa-Sindoor. / 06.2015 / PubMed / Full text
Effects of long-term resveratrol-induced SIRT1 activation on insulin and apoptotic signalling in aged skeletal muscle. / 12.2015 / PubMed / Full text
Hypothalamic expression of oestrogen receptor α and androgen receptor is sex-, age- and region-dependent in mice. / 04.2015 / PubMed / Full text
Species differences in androgen receptor expression in the medial preoptic and anterior hypothalamic areas of adult male and female rodents. / 22.01.2015 / PubMed / Full text
β-Adrenergic receptor blockade impairs coronary exercise hyperemia in young men but not older men. / 15.11.2014 / PubMed / Full text
Testosterone increases renal anti-aging klotho gene expression via the androgen receptor-mediated pathway. / 01.12.2014 / PubMed / Full text
Aging impairs VEGF-mediated, androgen-dependent regulation of angiogenesis. / 09.2014 / PubMed / Full text
Augmented reality cues to assist older drivers with gap estimation for left-turns. / 10.2014 / PubMed / Full text
Cytomegalovirus infection after acute rejection therapy in seropositive kidney transplant recipients. / 06.2014 / PubMed / Full text
Antiangiogenic and finasteride therapies: responses of the prostate microenvironment in elderly mice. / 13.06.2014 / PubMed / Full text
Distinct roles of age and abdominal visceral fat in reducing androgen receptor-dependent negative feedback on LH secretion in healthy men. / 07.2014 / PubMed / Full text
Pectinase-treated Panax ginseng extract (GINST) rescues testicular dysfunction in aged rats via redox-modulating proteins. / 05.2014 / PubMed / Full text
Differential impact of the expression of the androgen receptor by age in estrogen receptor-positive breast cancer. / 12.2013 / PubMed / Full text
Prostatic microenvironment in senescence: fibroblastic growth factors × hormonal imbalance. / 05.2014 / PubMed / Full text
Effects of exercise training on cardiovascular adrenergic system. / 28.11.2013 / PubMed / Full text
Antiobese function of platelet-activating factor: increased adiposity in platelet-activating factor receptor-deficient mice with age. / 01.2014 / PubMed / Full text
Effect of age on the contractile response of the rat carotid artery in the presence of sympathetic drugs and L-NAME. / 09.2013 / PubMed / Full text
The influence of dietary restriction before and after 10 weeks of age on osteochondrosis in growing gilts. / 11.2013 / PubMed / Full text

CP[править]

A Life Course Perspective on Growing Older With Cerebral Palsy. / 19.11.2020 / PubMed / Full text
The molecular anatomy and functions of the choroid plexus in healthy and diseased brain. / 01.11.2020 / PubMed / Full text
The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation. / 09.2020 / PubMed / Full text
Model based strategies towards protein A resin lifetime optimization and supervision. / 16.08.2020 / PubMed / Full text
The influence of age and environmental conditions on supplement intake by beef cattle winter grazing northern mixed-grass rangelands. / 01.07.2020 / PubMed / Full text
Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in mice. / 15.06.2020 / PubMed / Full text
Cepharanthine promotes the effect of dexmedetomidine on the deposition of β-amyloid in the old age of the senile dementia rat model by regulating inflammasome expression. / 2019 / PubMed / Full text
European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia. / 04.2020 / PubMed / Full text
Asymptomatic [i]Clostridium perfringens[/i] Inhabitation in Intestine Can Cause Inflammation, Apoptosis, and Disorders in Brain. / 01.2020 / PubMed / Full text
The Role of the Clinical Pharmacist in the Management of People Living with HIV in the Modern Antiretroviral Era. / 2019 / PubMed / Full text
A clinically feasible method for the assessment and characterization of pain in patients with chronic pancreatitis. / 01.2020 / PubMed / Full text
Differences in geometric strength at the contralateral hip between men with hip fracture and non-fractured comparators. / 03.2020 / PubMed / Full text
Factors associated with the number of clinical pharmacy recommendations: findings from an observational study in geriatric inpatients. / 23.10.2019 / PubMed / Full text
Protection against oxidative stress and anti-aging effect in Drosophila of royal jelly-collagen peptide. / 01.2020 / PubMed / Full text
[Investigation of signal molecules in saliva: prospects of application for diagnostics of myocardial infarction and the aging rate of different age people.] / 2019 / PubMed
Prevalence of drooling, swallowing, and feeding problems in cerebral palsy across the lifespan: a systematic review and meta-analyses. / 11.2019 / PubMed / Full text
Longitudinal Development of Receptive Vocabulary in Children with Cerebral Palsy and Anarthria: Use of the MacArthur-Bates CDI. / 07.2020 / PubMed / Full text
[Problem of mineral insufficiency at chronic pancreatitis in dependence on age]. / 2019 / PubMed / Full text
Systemic inflammation contributes to impairment of quality of life in chronic pancreatitis. / 13.05.2019 / PubMed / Full text
A Genotypic Comparison Reveals That the Improvement in Nitrogen Remobilization Efficiency in Oilseed Rape Leaves Is Related to Specific Patterns of Senescence-Associated Protease Activities and Phytohormones. / 2019 / PubMed / Full text
Keeping a 'watch-full' eye on metabolic disease. / 07.2013 / PubMed / Full text
Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. / 2018 / PubMed / Full text
Radiologic changes in the aging nasal cavity. / 01.04.2019 / PubMed / Full text
Influence of various concentrate-to-roughage ratios on dietary intake and nutrient digestibilities of weanling horses. / 01.2019 / PubMed / Full text
Ameliorative effect of zinc oxide nanoparticles on cyclophosphamide induced testicular injury in adult rat. / 10.2018 / PubMed / Full text
A Brain without Brakes: Reduced Inhibition Is Associated with Enhanced but Dysregulated Plasticity in the Aged Rat Auditory Cortex. / 07-08.2018 / PubMed / Full text
Energy expenditure is associated with age, anthropometric indicators and body composition in children with spastic cerebral palsy. / 02.08.2018 / PubMed / Full text
Microstructure and selected mechanical properties of aged Ti-15Zr-based alloys for biomedical applications. / 01.10.2018 / PubMed / Full text
The Impact of Aging, Psychotic Symptoms, Medication, and Brain-Derived Neurotrophic Factor on Cognitive Impairment in Japanese Chronic Schizophrenia Patients. / 2018 / PubMed / Full text
CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length. / 08.2018 / PubMed / Full text
Health conditions, functional status and health care utilization in adults with cerebral palsy. / 12.12.2018 / PubMed / Full text
Age-related Changes in Postural Sway During Sit-to-stand in Typical Children and Children with Cerebral Palsy. / 2019 / PubMed / Full text
The choroid plexus is an important circadian clock component. / 14.03.2018 / PubMed / Full text
Early development and reproductive lifespan of rabbit females: implications of growth rate, rearing diet and body condition at first mating. / 11.2018 / PubMed / Full text
Functional Capacity in Adults With Cerebral Palsy: Lower Limb Muscle Strength Matters. / 05.2018 / PubMed / Full text
Investigation of Petal Senescence by TRV-Mediated Virus-Induced Gene Silencing in Rose. / 2018 / PubMed / Full text
Immediate and late effects of chronic stress in the testes of prepubertal and adult rats. / 07-08.2018 / PubMed / Full text
Age related changes in balance performance during self-selected and narrow stance testing. / 03-04.2018 / PubMed / Full text
EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development. / 02.2018 / PubMed / Full text
The Effect of Insecticidal Stress on Reproductive Output of Susceptible and Field Strains of Aedes aegypti (Diptera: Culicidae). / 10.01.2018 / PubMed / Full text
The effect of five kinds of surface treatment agents on the bond strength to various ceramics with thermocycle aging. / 29.11.2017 / PubMed / Full text
Diffusion-weighted magnetic resonance imaging in the assessment of choroid plexus aging. / 10.2017 / PubMed / Full text
Prenatal ethanol exposure modifies locomotor activity and induces selective changes in Met-enk expression in adolescent rats. / 04.2017 / PubMed / Full text
Fatigue and its relationship with physical activity, age, and body composition in adults with cerebral palsy. / 04.2017 / PubMed / Full text
Motor sequencing in older adulthood: relationships with executive functioning and effects of complexity. / 04.2017 / PubMed / Full text
Ageing with cerebral palsy; what are the health experiences of adults with cerebral palsy? A qualitative study. / 13.10.2016 / PubMed / Full text
Influence of low protein diets on gene expression of digestive enzymes and hormone secretion in the gastrointestinal tract of young weaned piglets. / Oct..2016 / PubMed / Full text
Problematic clinical features of children and adults with cerebral palsy who use electric powered indoor/outdoor wheelchairs: A cross-sectional study. / Summer.2017 / PubMed / Full text
Providing Acute Care at Home: Community Paramedics Enhance an Advanced Illness Management Program-Preliminary Data. / 12.2016 / PubMed / Full text
Impact of aging on TREM-1 responses in the periodontium: a cross-sectional study in an elderly population. / 19.08.2016 / PubMed / Full text
Factors contributing to the longitudinal development of social participation in individuals with cerebral palsy. / 10.2016 / PubMed / Full text
Advanced maternal age causes adverse programming of mouse blastocysts leading to altered growth and impaired cardiometabolic health in post-natal life. / 09.2016 / PubMed / Full text
Communication changes experienced by adults with cerebral palsy as they age. / 12.2016 / PubMed / Full text
Effect of at-home bleaching with different thickeners and aging on physical properties of a nanocomposite. / 01-03.2016 / PubMed / Full text
Digestive evaluation of soy isolate protein as affected by heat treatment and soy oil inclusion in broilers at an early age. / 10.2016 / PubMed / Full text
Cold plasma: a novel approach to treat infected dentin-a combined ex vivo and in vitro study. / 12.2016 / PubMed / Full text
Age and adaptation to Ca and P deficiencies: 2. Impacts on amino acid digestibility and phytase efficacy in broilers. / 12.2015 / PubMed / Full text
A randomized controlled 27 years follow up of three resin composites in Class II restorations. / 12.2015 / PubMed / Full text
The head-shaft angle of the hip in early childhood: a comparison of reference values for children with cerebral palsy and normally developing hips. / 09.2015 / PubMed / Full text
One-year follow-up of at-home bleaching in smokers before and after dental prophylaxis. / 11.2015 / PubMed / Full text
Effects of chronic exposure to 950 MHz ultra-high-frequency electromagnetic radiation on reactive oxygen species metabolism in the right and left cerebral cortex of young rats of different ages. / 2015 / PubMed / Full text
Broiler responses to digestible threonine at different ages: a neural networks approach. / 08.2016 / PubMed / Full text
Effect of feeding guanidinoacetic acid and L-arginine on the fertility rate and sperm penetration in the perivitelline layer of aged broiler breeder hens. / 04.2016 / PubMed / Full text
Does low serum TSH within the normal range have negative impact on physical exercise capacity and quality of life of healthy elderly people? / 24.07.2015 / PubMed / Full text
[Association between carbonyl proteins and tumor necrosis factor alpha with muscle strength in young and older women: exploratory study]. / 11-12.2015 / PubMed / Full text
The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease. / 10.2015 / PubMed / Full text
Differences in skeletal components of temporomandibular joint of an early medieval and contemporary Croatian population obtained by different methods. / 01.2016 / PubMed / Full text
Annual changes in radiographic indices of the spine in cerebral palsy patients. / 03.2016 / PubMed / Full text
The choroid plexus and the paradox of interferons in the aging brain. / 02.2015 / PubMed / Full text
Carotid plaque as a predictor of dementia in older adults: the Three-City Study. / 03.2015 / PubMed / Full text
Expression of hepcidin at the choroid plexus in normal aging rats is associated with IL-6/Stat3 signaling pathway. / 25.12.2014 / PubMed
Standardized ileal digestibility of proteins and amino acids in sesame expeller and soya bean meal in weaning piglets. / 08.2015 / PubMed / Full text
Effects of protein and fat concentration in coproduct-based growing calf diets on performance and carcass composition. / 12.2014 / PubMed / Full text
The validation of a care partner-derived frailty index based upon comprehensive geriatric assessment (CP-FI-CGA) in emergency medical services and geriatric ambulatory care. / 03.2015 / PubMed / Full text
Collagen peptide and vitamin C additively attenuate age-related skin atrophy in Sod1-deficient mice. / 2014 / PubMed / Full text
Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson's disease. / 10.07.2014 / PubMed / Full text
Ageing does not affect flexion relaxation of erector spinae. / 1995 / PubMed / Full text
Amyloid-beta transporter expression at the choroid plexus in normal aging: the possibility of reduced resistance to oxidative stress insults. / 25.04.2014 / PubMed
Randomized phase II trial comparing carboplatin plus weekly paclitaxel and docetaxel alone in elderly patients with advanced non-small cell lung cancer: north japan lung cancer group trial 0801. / 04.2014 / PubMed / Full text
High-velocity resistance exercise protocols in older women: effects on cardiovascular response. / 2007 / PubMed / Full text
Measurement of choroid plexus perfusion using dynamic susceptibility MR imaging: capillary permeability and age-related changes. / 12.2013 / PubMed / Full text
Health, functioning, and participation of adolescents and adults with cerebral palsy: a review of outcomes research. / 2013 / PubMed / Full text
Gains and losses in creative personality as perceived by adults across the life span. / 03.2014 / PubMed / Full text
Postural stability in vestibular neuritis: age, disease duration, and residual vestibular function. / 04.2014 / PubMed / Full text
CNS-specific T cells shape brain function via the choroid plexus. / 11.2013 / PubMed / Full text
Gait function and decline in adults with cerebral palsy: a systematic review. / 2014 / PubMed / Full text
CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging. / 05.02.2013 / PubMed / Full text
Metabolizable protein supply while grazing dormant winter forage during heifer development alters pregnancy and subsequent in-herd retention rate. / 03.2013 / PubMed / Full text

PTEN[править]

Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2 mice. / 10.12.2020 / PubMed / Full text
Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis. / 26.10.2020 / PubMed / Full text
Alterations in Mitochondrial Dynamic-related Genes in the Peripheral Blood of Alzheimer's Disease Patients. / 2020 / PubMed / Full text
Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging. / 11.2020 / PubMed / Full text
Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells. / 10.08.2020 / PubMed / Full text
The precursor of PI(3,4,5)P alleviates aging by activating daf-18(Pten) and independent of daf-16. / 08.09.2020 / PubMed / Full text
Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis. / 25.08.2020 / PubMed / Full text
Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis. / 15.09.2020 / PubMed / Full text
Downregulation of PTEN mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy. / 05.2020 / PubMed / Full text
Inflamma-miR-21 Negatively Regulates Myogenesis during Ageing. / 23.04.2020 / PubMed / Full text
Peripheral Circulating Exosomal miRNAs Potentially Contribute to the Regulation of Molecular Signaling Networks in Aging. / 11.03.2020 / PubMed / Full text
HDAC inhibition leads to age-dependent opposite regenerative effect upon PTEN deletion in rubrospinal axons after SCI. / 06.2020 / PubMed / Full text
miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1. / 12.03.2020 / PubMed / Full text
Environmental Exposures and Asthma Development: Autophagy, Mitophagy, and Cellular Senescence. / 2019 / PubMed / Full text
Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text
PTEN loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation. / 17.09.2019 / PubMed / Full text
Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. / 08.2019 / PubMed / Full text
Role of IL-37 in Cardiovascular Disease Inflammation. / 07.2019 / PubMed / Full text
Abrogation of B-Raf induced senescence by FoxM1 expression. / 27.08.2019 / PubMed / Full text
Oncogenic mutations in histologically normal endometrium: the new normal? / 10.2019 / PubMed / Full text
Double knockout of Akt2 and AMPK predisposes cardiac aging without affecting lifespan: Role of autophagy and mitophagy. / 01.07.2019 / PubMed / Full text
Single Cell Profiling Reveals PTEN Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy. / 21.02.2019 / PubMed / Full text
KIN-4/MAST kinase promotes PTEN-mediated longevity of Caenorhabditis elegans via binding through a PDZ domain. / 06.2019 / PubMed / Full text
Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF-κB activation. / 02.2019 / PubMed / Full text
Increased susceptibility of aging gastric mucosa to injury and delayed healing: Clinical implications. / 14.11.2018 / PubMed / Full text
PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. / 03.2019 / PubMed / Full text
MCL1 gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway. / 01.2019 / PubMed / Full text
Grape skin extract improves muscle function and extends lifespan of a Drosophila model of Parkinson's disease through activation of mitophagy. / 11.2018 / PubMed / Full text
Berberine ameliorates renal injury in a rat model of D-galactose-induced aging through a PTEN/Akt-dependent mechanism. / 05.2020 / PubMed / Full text
Neuronal Preconditioning Requires the Mitophagic Activity of C-terminus of HSC70-Interacting Protein. / 01.08.2018 / PubMed / Full text
Endothelial replicative senescence delayed by the inhibition of MTORC1 signaling involves MicroRNA-107. / 08.2018 / PubMed / Full text
Stanozolol administration combined with exercise leads to decreased telomerase activity possibly associated with liver aging. / 07.2018 / PubMed / Full text
Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-HDAC1-mediated regulation of autophagy. / 06.2018 / PubMed / Full text
Changes in expression of special AT-rich sequence binding protein 1 and phosphatase and tensin homologue in kidneys of diabetic rats during ageing. / 01.10.2018 / PubMed / Full text
Beyond regulation of pol III: Role of MAF1 in growth, metabolism, aging and cancer. / 04.2018 / PubMed / Full text
Neuronal PTEN deletion in adult cortical neurons triggers progressive growth of cell bodies, dendrites, and axons. / 05.2018 / PubMed / Full text
Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating PTEN. / 15.03.2018 / PubMed / Full text
miR-21 suppression prevents cardiac alterations induced by d-galactose and doxorubicin. / 02.2018 / PubMed / Full text
MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting SPRY1 via the PTEN/PI3K/AKT signaling pathway. / 05.2018 / PubMed / Full text
Global mapping of transcription factor motifs in human aging. / 2018 / PubMed / Full text
CRISPR-Cas9 Mediated Telomere Removal Leads to Mitochondrial Stress and Protein Aggregation. / 03.10.2017 / PubMed / Full text
Akt2 ablation prolongs life span and improves myocardial contractile function with adaptive cardiac remodeling: role of Sirt1-mediated autophagy regulation. / 10.2017 / PubMed / Full text
PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells. / 11.07.2017 / PubMed / Full text
Cell Cycle Control by PTEN. / 21.07.2017 / PubMed / Full text
PTEN, Longevity and Age-Related Diseases. / 13.12.2013 / PubMed / Full text
Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate. / 09.05.2017 / PubMed / Full text
A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer. / 04.2017 / PubMed / Full text
Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging. / 06.2017 / PubMed / Full text
Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease. / 04.2017 / PubMed / Full text
Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice. / 31.01.2017 / PubMed / Full text
Identification of [i]Salvia haenkei[/i] as gerosuppressant agent by using an integrated senescence-screening assay. / 01.12.2016 / PubMed / Full text
Altered mitochondrial quality control signaling in muscle of old gastric cancer patients with cachexia. / 01.2017 / PubMed / Full text
Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways. / 02.2017 / PubMed / Full text
GBM-associated mutations and altered protein expression are more common in young patients. / 25.10.2016 / PubMed / Full text
C. elegans Methods to Study PTEN. / 2016 / PubMed / Full text
Inorganic Phosphate Activates the AKT/mTORC1 Pathway and Shortens the Life Span of an α‑Klotho-Deficient Model. / 09.2016 / PubMed / Full text
A PTEN inhibitor displays preclinical activity against hepatocarcinoma cells. / 2016 / PubMed / Full text
Effect of TIMP1 transfection on PTEN expression in human kidney proximal tubular cells. / 21.12.2015 / PubMed / Full text
Ribosomal L1 domain and lysine-rich region are essential for CSIG/ RSL1D1 to regulate proliferation and senescence. / 15.01.2016 / PubMed / Full text
PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland. / 01.01.2016 / PubMed / Full text
Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text
Effects of age and unaccustomed resistance exercise on mitochondrial transcript and protein abundance in skeletal muscle of men. / 15.04.2015 / PubMed / Full text
PTEN/Akt-p27(kip1) Signaling Promote the BM-MSCs Senescence and Apoptosis in SLE Patients. / 08.2015 / PubMed / Full text
Loss of JUNB/AP-1 promotes invasive prostate cancer. / 04.2015 / PubMed / Full text
Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN. / 01.2015 / PubMed / Full text
Mammalian target of rapamycin's distinct roles and effectiveness in promoting compensatory axonal sprouting in the injured CNS. / 12.11.2014 / PubMed / Full text
A functional genomic screen for evolutionarily conserved genes required for lifespan and immunity in germline-deficient C. elegans. / 2014 / PubMed / Full text
Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease. / 10.2014 / PubMed / Full text
Impact of ketamine on learning and memory function, neuronal apoptosis and its potential association with miR-214 and PTEN in adolescent rats. / 2014 / PubMed / Full text
Increased susceptibility of aging gastric mucosa to injury: the mechanisms and clinical implications. / 28.04.2014 / PubMed / Full text
Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma. / 07.2014 / PubMed / Full text
[Reinnervation of central visual areas and recovery of visual functions following optic nerve regeneration in adult mice]. / 03.2014 / PubMed
High-resolution profiling of stationary-phase survival reveals yeast longevity factors and their genetic interactions. / 02.2014 / PubMed / Full text
Insulin/IGF1 signaling inhibits age-dependent axon regeneration. / 05.02.2014 / PubMed / Full text
AKT activation promotes PTEN hamartoma tumor syndrome-associated cataract development. / 12.2013 / PubMed / Full text
Adult-onset deletion of Pten increases islet mass and beta cell proliferation in mice. / 02.2014 / PubMed / Full text
Drosophila ref(2)P is required for the parkin-mediated suppression of mitochondrial dysfunction in pink1 mutants. / 24.10.2013 / PubMed / Full text
Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR). / 01.11.2013 / PubMed / Full text
Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development. / 2013 / PubMed / Full text
PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a. / 12.2013 / PubMed / Full text
Overexpression of phosphatase and tensin homolog improves fitness and decreases Plasmodium falciparum development in Anopheles stephensi. / 11.2013 / PubMed / Full text
Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism. / 19.03.2013 / PubMed / Full text
PTEN in cancer, metabolism, and aging. / 04.2013 / PubMed / Full text

SIRT6[править]

Association between SIRT6 Methylation and Human Longevity in a Chinese Population. / 25.11.2020 / PubMed / Full text
Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression. / 10.11.2020 / PubMed / Full text
Melatonin and Sirtuins in Buccal Epithelium: Potential Biomarkers of Aging and Age-Related Pathologies. / 30.10.2020 / PubMed / Full text
The SIRT6 activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells. / 08.2020 / PubMed / Full text
Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva. / 10.2020 / PubMed / Full text
FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. / 14.10.2020 / PubMed / Full text
The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. / 11.2020 / PubMed / Full text
Intrinsic Type 1 Interferon (IFN1) Profile of Uncultured Human Bone Marrow CD45 CD271 Multipotential Stromal Cells (BM-MSCs): The Impact of Donor Age, Culture Expansion and IFNα and IFNβ Stimulation. / 15.07.2020 / PubMed / Full text
Age-related epigenetic drift deregulates [i]SIRT6[/i] expression and affects its downstream genes in human peripheral blood mononuclear cells. / 12.2020 / PubMed / Full text
SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. / 25.06.2020 / PubMed / Full text
Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators. / 07.08.2020 / PubMed / Full text
Age-dependent role of SIRT6 in jawbone via regulating senescence and autophagy of bone marrow stromal cells. / 02.2020 / PubMed / Full text
The effect of high glucose on the biological characteristics of nucleus pulposus-derived mesenchymal stem cells. / 03.2020 / PubMed / Full text
Mechanism of activation for the sirtuin 6 protein deacylase. / 31.01.2020 / PubMed / Full text
Sirtuin 6 deficiency transcriptionally up-regulates TGF-β signaling and induces fibrosis in mice. / 10.01.2020 / PubMed / Full text
Proteomics of Long-Lived Mammals. / 03.2020 / PubMed / Full text
Sirtuins and SIRT6 in Carcinogenesis and in Diet. / 07.10.2019 / PubMed / Full text
Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure. / 13.02.2020 / PubMed / Full text
SIRT6-mediated transcriptional suppression of MALAT1 is a key mechanism for endothelial to mesenchymal transition. / 15.11.2019 / PubMed / Full text
SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. / 18.04.2019 / PubMed / Full text
SIRT6 participates in the quality control of aged oocytes via modulating telomere function. / 29.03.2019 / PubMed / Full text
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation. / 02.04.2019 / PubMed / Full text
Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. / 23.01.2019 / PubMed / Full text
Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice. / 15.04.2019 / PubMed / Full text
Phosphodiesterase 4 inhibitor activates AMPK-SIRT6 pathway to prevent aging-related adipose deposition induced by metabolic disorder. / 18.09.2018 / PubMed / Full text
MiR-125b attenuates human hepatocellular carcinoma malignancy through targeting SIRT6. / 2018 / PubMed / Full text
Role of accelerated aging in limb muscle wasting of patients with COPD. / 2018 / PubMed / Full text
A Review of the Recent Advances Made with SIRT6 and its Implications on Aging Related Processes, Major Human Diseases, and Possible Therapeutic Targets. / 29.06.2018 / PubMed / Full text
Application of multivariate longitudinal models in SIRT6, FBS, and BMI analysis of the elderly. / 12.2019 / PubMed / Full text
Sirtuins in Renal Health and Disease. / 07.2018 / PubMed / Full text
Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria. / 02.05.2018 / PubMed / Full text
High expression of CPT1b in skeletal muscle in metabolically healthy older subjects. / 04.2019 / PubMed / Full text
Haploinsufficiency of [i]Trp53[/i] dramatically extends the lifespan of Sirt6-deficient mice. / 23.02.2018 / PubMed / Full text
SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™). / 04.2018 / PubMed / Full text
Aging as an Epigenetic Phenomenon. / 10.2017 / PubMed / Full text
Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. / 2017 / PubMed / Full text
SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection. / 10.03.2018 / PubMed / Full text
Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers. / 2018 / PubMed / Full text
Characterization of physiological defects in adult SIRT6-/- mice. / 2017 / PubMed / Full text
Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. / 01.06.2017 / PubMed / Full text
SIRT6 polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men. / 11.04.2017 / PubMed / Full text
Neuroprotective Functions for the Histone Deacetylase SIRT6. / 28.03.2017 / PubMed / Full text
Cosmeceutical product consisting of biomimetic peptides: antiaging effects in vivo and in vitro. / 2017 / PubMed / Full text
Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders. / 03.2017 / PubMed / Full text
SIRT6: Novel Mechanisms and Links to Aging and Disease. / 03.2017 / PubMed / Full text
Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases. / 05.2017 / PubMed / Full text
SIRT6 delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation. / 16.09.2016 / PubMed / Full text
The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging. / 12.2016 / PubMed / Full text
SIRT6 Overexpression Improves Various Aspects of Mouse Healthspan. / 01.05.2017 / PubMed / Full text
Slowing ageing by design: the rise of NAD and sirtuin-activating compounds. / 11.2016 / PubMed / Full text
Ursolic acid regulates aging process through enhancing of metabolic sensor proteins level. / 08.2016 / PubMed / Full text
Ergothioneine oxidation in the protection against high-glucose induced endothelial senescence: Involvement of SIRT1 and SIRT6. / 07.2016 / PubMed / Full text
Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins. / 15.06.2016 / PubMed / Full text
AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions. / 08.2016 / PubMed / Full text
Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling. / 2016 / PubMed / Full text
Sirtuins, Cell Senescence, and Vascular Aging. / 05.2016 / PubMed / Full text
Lack of association between polymorphisms in the SIRT6 gene and longevity in a Chinese population. / 04.2016 / PubMed / Full text
SIRT6, oxidative stress, and aging. / 02.2016 / PubMed / Full text
Sirt6 regulates dendritic cell differentiation, maturation, and function. / 01.2016 / PubMed / Full text
The complex role of SIRT6 in carcinogenesis. / 02.2016 / PubMed / Full text
The expression levels of the sirtuins in patients with BCC. / 05.2016 / PubMed / Full text
Localization of sirtuins (SIRT1-7) in the aged mouse inner ear. / 2016 / PubMed / Full text
Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells. / 01.2016 / PubMed / Full text
Are sirtuins markers of ovarian aging? / 10.01.2016 / PubMed / Full text
Sirtuin-dependent clock control: new advances in metabolism, aging and cancer. / 11.2015 / PubMed / Full text
SIRT6/NF-κB signaling axis in ginsenoside Rg1-delayed hematopoietic stem/progenitor cell senescence. / 2015 / PubMed / Full text
Differential expression of sirtuins in the aging rat brain. / 2015 / PubMed / Full text
Scopoletin has a potential activity for anti-aging via autophagy in human lung fibroblasts. / 15.03.2015 / PubMed / Full text
Depletion of SIRT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes. / 08.2015 / PubMed / Full text
Sirtuin 6 promotes transforming growth factor-β1/H2O2/HOCl-mediated enhancement of hepatocellular carcinoma cell tumorigenicity by suppressing cellular senescence. / 05.2015 / PubMed / Full text
SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age. / 23.09.2014 / PubMed / Full text
Changes in human sirtuin 6 gene promoter methylation during aging. / 07.2014 / PubMed / Full text
Sirtuins: guardians of mammalian healthspan. / 07.2014 / PubMed / Full text
Comparative interactomes of SIRT6 and SIRT7: Implication of functional links to aging. / 07.2014 / PubMed / Full text
Chromatin and beyond: the multitasking roles for SIRT6. / 02.2014 / PubMed / Full text
Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging. / 17.01.2014 / PubMed / Full text
SIRT6, a protein with many faces. / 12.2013 / PubMed / Full text
Obesity accelerates ovarian follicle development and follicle loss in rats. / 01.2014 / PubMed / Full text
Transcriptional and phenotypic changes in aorta and aortic valve with aging and MnSOD deficiency in mice. / 15.11.2013 / PubMed / Full text
The contentious history of sirtuin debates. / 10.2012 / PubMed / Full text
The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells. / 21.06.2013 / PubMed / Full text

TLR4[править]

Cigarette smoke induction of S100A9 contributes to chronic obstructive pulmonary disease. / 23.09.2020 / PubMed / Full text
Age-Dependent Changes of Adipokine and Cytokine Secretion From Rat Adipose Tissue by Endogenous and Exogenous Toll-Like Receptor Agonists. / 2020 / PubMed / Full text
Role of Toll Like Receptor 4 in Alzheimer's Disease. / 2020 / PubMed / Full text
Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. / 01.12.2020 / PubMed / Full text
Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose. / 04.11.2020 / PubMed / Full text
Contribution of Porphyromonas gingivalis lipopolysaccharide to experimental periodontitis in relation to aging. / 26.08.2020 / PubMed / Full text
Commentary on Some Recent Theses Relevant to Combating Aging: August 2020. / 08.2020 / PubMed / Full text
Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration. / 2020 / PubMed / Full text
Chemerin facilitates intervertebral disc degeneration via TLR4 and CMKLR1 and activation of NF-kB signaling pathway. / 11.06.2020 / PubMed / Full text
Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress. / 08.2020 / PubMed / Full text
Toll-like receptor 4 differentially regulates adult hippocampal neurogenesis in an age- and sex-dependent manner. / 09.2020 / PubMed / Full text
Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. / 27.01.2020 / PubMed / Full text
Aging-associated immunosenescence via alterations in splenic immune cell populations in rat. / 15.01.2020 / PubMed / Full text
Leptin induces immunosenescence in human B cells. / 02.2020 / PubMed / Full text
Cellular senescence induced by S100A9 in mesenchymal stromal cells through NLRP3 inflammasome activation. / 14.11.2019 / PubMed / Full text
Biomarkers for vascular ageing in aorta tissues and blood samples. / 12.2019 / PubMed / Full text
Accelerated decline in cognition in a mouse model of increased oxidative stress. / 10.2019 / PubMed / Full text
Genetic Variation in the Magnitude and Longevity of the IgG Subclass Response to a Diphtheria-Tetanus-Acellular Pertussis (DTaP) Vaccine in Mice. / 20.09.2019 / PubMed / Full text
Rapamycin improves sevoflurane‑induced cognitive dysfunction in aged rats by mediating autophagy through the TLR4/MyD88/NF‑κB signaling pathway. / 10.2019 / PubMed / Full text
Targeting HMGB1 by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells. / 14.07.2019 / PubMed / Full text
Age-dependent effect between MARCO and TLR4 on PMMA particle phagocytosis by macrophages. / 08.2019 / PubMed / Full text
Regulation of Toll-Like Receptor (TLR) Signaling Pathway by Polyphenols in the Treatment of Age-Linked Neurodegenerative Diseases: Focus on TLR4 Signaling. / 2019 / PubMed / Full text
TLR4 Promotes and DAP12 Limits Obesity-Induced Osteoarthritis in Aged Female Mice. / 04.2019 / PubMed / Full text
Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis. / 27.02.2019 / PubMed / Full text
Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16 . / 06.2019 / PubMed / Full text
Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. / 04.2019 / PubMed / Full text
Aging leads to dysfunctional innate immune responses to TLR2 and TLR4 agonists. / 09.2019 / PubMed / Full text
Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells. / 05.2019 / PubMed / Full text
Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-HDAC1-mediated regulation of autophagy. / 06.2018 / PubMed / Full text
Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging. / 05.2018 / PubMed / Full text
Inflammation, insulin signaling and cognitive function in aged APP/PS1 mice. / 05.2018 / PubMed / Full text
Repeated stimulation by LPS promotes the senescence of DPSCs via TLR4/MyD88-NF-κB-p53/p21 signaling. / 06.2018 / PubMed / Full text
Ageing potentiates diet-induced glucose intolerance, β-cell failure and tissue inflammation through TLR4. / 09.02.2018 / PubMed / Full text
Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice. / 03.2018 / PubMed / Full text
Granzyme A in Human Platelets Regulates the Synthesis of Proinflammatory Cytokines by Monocytes in Aging. / 01.01.2018 / PubMed / Full text
TLR4 and TLR2 activation is differentially associated with age during Parkinson's disease. / 01.2018 / PubMed / Full text
Toll-like receptor 4 (TLR4) deficient mice are protected from adipose tissue inflammation in aging. / 07.09.2017 / PubMed / Full text
Role of pattern recognition receptors of the neurovascular unit in inflamm-aging. / 01.11.2017 / PubMed / Full text
Exenatide mitigated diet-induced vascular aging and atherosclerotic plaque growth in ApoE-deficient mice under chronic stress. / 09.2017 / PubMed / Full text
Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists. / 15.08.2017 / PubMed / Full text
A dual agonist of farnesoid X receptor (FXR) and the G protein-coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice. / 21.07.2017 / PubMed / Full text
The critical role played by endotoxin-induced liver autophagy in the maintenance of lipid metabolism during sepsis. / 03.07.2017 / PubMed / Full text
Growth performance, reproductive traits and offspring survivability of genetically modified rams overexpressing toll-like receptor 4. / 01.07.2017 / PubMed / Full text
Increased dipeptidyl peptidase-4 accelerates diet-related vascular aging and atherosclerosis in ApoE-deficient mice under chronic stress. / 15.09.2017 / PubMed / Full text
Age-related changes and distribution of T cell markers (CD3 and CD4) and toll-like receptors(TLR2, TLR3,TLR4 and TLR7) in the duck lymphoid organs. / 07.2017 / PubMed / Full text
Aging and amyloid β oligomers enhance TLR4 expression, LPS-induced Ca responses, and neuron cell death in cultured rat hippocampal neurons. / 31.01.2017 / PubMed / Full text
Attenuated recovery of contractile function in aging hearts following global ischemia/reperfusion: Role of extracellular HSP27 and TLR4. / 01.2017 / PubMed / Full text
Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. / 02.2017 / PubMed / Full text
Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. / 01.12.2016 / PubMed / Full text
Strain-dependent response to stimulation in middle-aged rat macrophages: A quest after a useful indicator of healthy aging. / 01.12.2016 / PubMed / Full text
Microglial response to LPS increases in wild-type mice during aging but diminishes in an Alzheimer's mouse model: Implication of TLR4 signaling in disease progression. / 14.10.2016 / PubMed / Full text
Aging increases the susceptibility of hepatic inflammation, liver fibrosis and aging in response to high-fat diet in mice. / 08.2016 / PubMed / Full text
Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice. / 2016 / PubMed / Full text
In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant. / 07.2016 / PubMed / Full text
Effects of aerobic training on markers of autophagy in the elderly. / 04.2016 / PubMed / Full text
Reduced levels of cytosolic DNA sensor AIM2 are associated with impaired cytokine responses in healthy elderly. / 06.2016 / PubMed / Full text
Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates. / 05.2016 / PubMed / Full text
Gut microbiota lipopolysaccharide accelerates inflamm-aging in mice. / 16.01.2016 / PubMed / Full text
Direct Regulation of TLR5 Expression by Caveolin-1. / 12.2015 / PubMed / Full text
Anti-Inflamm-Aging Effects of Long-Term Caloric Restriction via Overexpression of SIGIRR to Inhibit NF-κB Signaling Pathway. / 2015 / PubMed / Full text
Lead exposure induced microgliosis and astrogliosis in hippocampus of young mice potentially by triggering TLR4-MyD88-NFκB signaling cascades. / 03.12.2015 / PubMed / Full text
Monocyte Phenotype and Polyfunctionality Are Associated With Elevated Soluble Inflammatory Markers, Cytomegalovirus Infection, and Functional and Cognitive Decline in Elderly Adults. / 05.2016 / PubMed / Full text
Flagellin-dependent TLR5/caveolin-1 as a promising immune activator in immunosenescence. / 10.2015 / PubMed / Full text
Decreased serum level of HMGB1 and MyD88 during human aging progress in healthy individuals. / 04.2016 / PubMed / Full text
The stimulatory effect of the TLR4-mediated adjuvant glucopyranosyl lipid A is well preserved in old age. / 02.2016 / PubMed / Full text
Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium. / 06.2015 / PubMed / Full text
Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli. / 09.04.2015 / PubMed / Full text
Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. / 06.2015 / PubMed / Full text
Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal TLR4 activation in aged rats. / 05.2015 / PubMed / Full text
Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture. / 05.2015 / PubMed / Full text
Aging does not affect the ability of human monocyte-derived dendritic cells to phagocytose Candida albicans. / 12.2015 / PubMed / Full text
Aging oppositely affects TNF-α and IL-10 production by macrophages from different rat strains. / 2014 / PubMed / Full text
Bacteria and Toll-like receptor and cytokine mRNA expression profiles associated with canine arthritis. / 15.08.2014 / PubMed / Full text
Elevated muscle TLR4 expression and metabolic endotoxemia in human aging. / 02.2015 / PubMed / Full text
Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals. / 08.2014 / PubMed / Full text
Hip fracture aggravates systemic inflammation and lung injury in aged chronic cigarette smoke exposed rats. / 01.2014 / PubMed / Full text
Carbocysteine regulates innate immune responses and senescence processes in cigarette smoke stimulated bronchial epithelial cells. / 25.11.2013 / PubMed / Full text
Dendritic cells from the elderly display an intrinsic defect in the production of IL-10 in response to lithium chloride. / 11.2013 / PubMed / Full text
[Effects of total paeony glucosides on mRNA expressions of Toll receptors and interleukin-33 in the brain tissue of D-galactose induced aging rats: an experimental research]. / 06.2013 / PubMed
Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults. / 01.08.2013 / PubMed / Full text
Microglia express distinct M1 and M2 phenotypic markers in the postnatal and adult central nervous system in male and female mice. / 09.2013 / PubMed / Full text
Repairing DNA damage by XRCC6/KU70 reverses TLR4-deficiency-worsened HCC development via restoring senescence and autophagic flux. / 01.06.2013 / PubMed / Full text

CGA[править]

Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric assessment: A planned interim analysis of a multicenter, phase II trial. / 04.11.2020 / PubMed / Full text
The Protective Effect of Chlorogenic Acid on Vascular Senescence via the Nrf2/HO-1 Pathway. / 25.06.2020 / PubMed / Full text
Association between comprehensive geriatric assessment and short-term outcomes among older adult patients with stroke: A nationwide retrospective cohort study using propensity score and instrumental variable methods. / 06.2020 / PubMed / Full text
Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis. / 12.2020 / PubMed / Full text
A Computerized Frailty Assessment Tool at Points-of-Care: Development of a Standalone Electronic Comprehensive Geriatric Assessment/Frailty Index (eFI-CGA). / 2020 / PubMed / Full text
Allocating patients to geriatric medicine wards in a tertiary university hospital in England: A service evaluation of the Specialist Advice for the Frail Elderly (SAFE) team. / 09.2018 / PubMed / Full text
Role of Frailty on Risk Stratification in Cardiac Surgery and Procedures. / 2020 / PubMed / Full text
Developing an objective structured clinical examination in comprehensive geriatric assessment - A pilot study. / 05-08.2019 / PubMed / Full text
How do doctors choose treatment for older gynecological cancer patients? A Japanese Gynecologic Oncology Group survey of gynecologic oncologists. / 04.2020 / PubMed / Full text
Validation of the Pictorial Fit-Frail Scale in a memory clinic setting. / 09.2020 / PubMed / Full text
Impact of Resolution of Hyponatremia on Neurocognitive and Motor Performance in Geriatric Patients. / 29.08.2019 / PubMed / Full text
Health outcome of older hospitalized patients in internal medicine environments evaluated by Identification of Seniors at Risk (ISAR) screening and geriatric assessment. / 14.08.2019 / PubMed / Full text
What will perioperative geriatric assessment for older cancer patients look like in 2025? Advantages and limitations of new technologies in geriatric assessment. / 03.2020 / PubMed / Full text
Impact of comprehensive geriatric assessment on short-term mortality in older patients with cancer-a follow-up study. / 07.2019 / PubMed / Full text
Comprehensive Geriatric Assessment in the perioperative setting; where next? / 01.09.2019 / PubMed / Full text
Use of comprehensive geriatric assessment (CGA) to define frailty in geriatric oncology: Searching for the best threshold. Cross-sectional study of 418 old patients with cancer evaluated in the Geriatric Frailty Clinic (G.F.C.) of Toulouse (France). / 11.2019 / PubMed / Full text
The prognostic significance of geriatric syndromes and resources. / 01.2020 / PubMed / Full text
Functional status in a geriatric oncology setting: A review. / 11.2019 / PubMed / Full text
Changes in the Use of Comprehensive Geriatric Assessment in Clinical Trials for Older Patients with Cancer over Time. / 08.2019 / PubMed / Full text
Predictive values of two frailty screening tools in older patients with solid cancer: a comparison of SAOP2 and G8. / 12.10.2018 / PubMed / Full text
New associations of the Multidimensional Prognostic Index. / 08.2019 / PubMed / Full text
Is care based on comprehensive geriatric assessment with mobile teams better than usual care? A study protocol of a randomised controlled trial (The GerMoT study). / 10.10.2018 / PubMed / Full text
[The Comprehensive Geriatric Assessment predicts healthy life expectancy better than health checkups in older people: JAGES cohort study]. / 2018 / PubMed / Full text
Outpatient comprehensive geriatric assessment: effects on frailty and mortality in old people with multimorbidity and high health care utilization. / 04.2019 / PubMed / Full text
Beyond the black box of geriatric assessment: Understanding enhancements to care by the geriatric oncology clinic. / 11.2018 / PubMed / Full text
General recommendations paper on the management of older patients with cancer: the SEOM geriatric oncology task force's position statement. / 10.2018 / PubMed / Full text
Delirium, Frailty, and Fast-Track Surgery in Oncogeriatrics: Is There a Link? / 01-04.2018 / PubMed / Full text
Screening for cognitive impairment in an Australian aged care assessment team as part of comprehensive geriatric assessment. / 05.2019 / PubMed / Full text
Comprehensive Geriatric Assessment in the Older Adult with Cancer: A Review. / 10.2017 / PubMed / Full text
Frailty: A global measure of the multisystem impact of COPD. / 11.2018 / PubMed / Full text
Delphi consensus of an expert committee in oncogeriatrics regarding comprehensive geriatric assessment in seniors with cancer in Spain. / 07.2018 / PubMed / Full text
The added value of clinical geriatric assessment prior to geriatric rehabilitation. / 12.2017 / PubMed
What is Comprehensive Geriatric Assessment (CGA)? An umbrella review. / 01.01.2018 / PubMed / Full text
[Geriatric assessment and prognostic scores in older cancer patient: Additional support to the therapeutic decision?] / 11.2017 / PubMed / Full text
Preadmission Functional Decline Predicts Functional Improvement Among Older Patients Admitted to Acute Care Hospital. / 11.09.2018 / PubMed / Full text
Towards a biological geriatric assessment. / 01.07.2018 / PubMed / Full text
The potential clinical benefits of medicines optimisation through comprehensive geriatric assessment, carried out by secondary care geriatricians, in a general practice care setting in North Staffordshire, UK: a feasibility study. / 28.09.2017 / PubMed / Full text
New horizons in comprehensive geriatric assessment. / 01.09.2017 / PubMed / Full text
Acute geriatrics at the front door. / 07.2017 / PubMed / Full text
Assessment and management of radiotherapy induced toxicity in older patients. / 11.2017 / PubMed / Full text
Hospital-at-home Integrated Care Programme for the management of disabling health crises in older patients: comparison with bed-based Intermediate Care. / 01.11.2017 / PubMed / Full text
Arginine CGA codons as a source of nonsense mutations: a possible role in multivariant gene expression, control of mRNA quality, and aging. / 10.2017 / PubMed / Full text
The growing challenge of major trauma in older people: a role for comprehensive geriatric assessment? / 01.09.2017 / PubMed / Full text
Modeling individual and relative accuracy of screening tools in geriatric oncology. / 01.05.2017 / PubMed / Full text
[Geriatric inpatients with iron deficiency-associated Restless Legs Syndrome. A retrospective analysis]. / 03.2017 / PubMed / Full text
Frailty affects the initial treatment response and time to recovery of mobility in acutely ill older adults admitted to hospital. / 01.11.2017 / PubMed / Full text
Three Decades of Comprehensive Geriatric Assessment: Evidence Coming From Different Healthcare Settings and Specific Clinical Conditions. / 01.02.2017 / PubMed / Full text
Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a scoping review of the literature and international policies. / 01.05.2017 / PubMed / Full text
Can consultant geriatrician led comprehensive geriatric assessment in the emergency department reduce hospital admission rates? A systematic review. / 01.05.2017 / PubMed / Full text
Assessment of frailty in aged dogs. / 12.2016 / PubMed / Full text
Asymptomatic and yet C. difficile-toxin positive? Prevalence and risk factors of carriers of toxigenic Clostridium difficile among geriatric in-patients. / 15.11.2016 / PubMed / Full text
Palliative Care of Cancer in the Older Patient. / 12.2016 / PubMed / Full text
Comprehensive geriatric assessment: recognition of identified geriatric conditions by community-dwelling older persons. / 11.2016 / PubMed / Full text
Frailty as determined by a comprehensive geriatric assessment-derived deficit-accumulation index in older patients with cancer who receive chemotherapy. / 15.12.2016 / PubMed / Full text
Chlorogenic Acid Extends the Lifespan of Caenorhabditis elegans via Insulin/IGF-1 Signaling Pathway. / 01.04.2017 / PubMed / Full text
Gastrointestinal Microbiota and Their Contribution to Healthy Aging. / 2016 / PubMed / Full text
Current Development in Elderly Comprehensive Assessment and Research Methods. / 2016 / PubMed / Full text
New horizons in the implementation and research of comprehensive geriatric assessment: knowing, doing and the 'know-do' gap. / 03.2016 / PubMed / Full text
Evaluating Outcomes from an Integrated Health Service for Older Patients. / Winter.2015 / PubMed / Full text
The assessment and management of older cancer patients: A SIOG surgical task force survey on surgeons' attitudes. / 02.2016 / PubMed / Full text
Factors associated with recognition and prioritization for falling, and the effect on fall incidence in community dwelling older adults. / 17.12.2015 / PubMed / Full text
Frailty in Primary Care. / 2015 / PubMed / Full text
Integrating Geriatrics Into Oncology Ambulatory Care Clinics / 08.2015 / PubMed / Full text
[Cancer treatment in elderly patients: evidence and clinical research]. / 01.2015 / PubMed / Full text
Integrating Nutrition in the Comprehensive Geriatric Assessment. / 08.2014 / PubMed / Full text
[Geriatric assessment tools in Spanish Geriatric Departments]. / 09-10.2014 / PubMed / Full text
Development of a comprehensive multidisciplinary geriatric oncology center, the Thomas Jefferson University Experience. / 04.2014 / PubMed / Full text
Characteristics and treatment options of elderly Chinese patients with cancer as determined by Comprehensive Geriatric Assessment (CGA). / 04.2014 / PubMed / Full text
Geriatric screening results and the association with severe treatment toxicity after the first cycle of (radio)chemotherapy. / 04.2014 / PubMed / Full text
Assessment of health status in elderly patients with cancer. / 2012 / PubMed / Full text
UK medical teaching about ageing is improving but there is still work to be done: the Second National Survey of Undergraduate Teaching in Ageing and Geriatric Medicine. / 03.2014 / PubMed / Full text
The risk of adverse outcomes in hospitalized older patients in relation to a frailty index based on a comprehensive geriatric assessment. / 01.2014 / PubMed / Full text
Immune senescence and cancer in elderly patients: results from an exploratory study. / 12.2013 / PubMed / Full text
[Meagre evidence so far for effectiveness of in-home comprehensive geriatric assessment: a literature review]. / 10.2013 / PubMed / Full text
Geriatric assessment in undergraduate geriatric education - a structured interpretation guide improves the quantity and accuracy of the results: a cohort comparison. / 30.08.2013 / PubMed / Full text
A controlled evaluation of comprehensive geriatric assessment in the emergency department: the 'Emergency Frailty Unit'. / 01.2014 / PubMed / Full text
Differential pathways for interleukin-1β production activated by chromogranin A and amyloid β in microglia. / 12.2013 / PubMed / Full text
Is comprehensive geriatric assessment recognized and applied in Southwest China? A survey from Sichuan Association of Geriatrics. / 10.2013 / PubMed / Full text
Predicting outcome after hip fracture: using a frailty index to integrate comprehensive geriatric assessment results. / 01.2014 / PubMed / Full text
Expert consensus of the French Society of Geriatrics and Gerontology and the French Society of Cardiology on the management of atrial fibrillation in elderly people. / 05.2013 / PubMed / Full text
Tools for decision-making in older cancer patients. Role of the comprehensive geriatric assessment. / 06.2014 / PubMed / Full text

ACE[править]

ACE2/ACE imbalance and impaired vasoreparative functions of stem/progenitor cells in aging. / 27.11.2020 / PubMed / Full text
Elite swimmers possess shorter telomeres than recreationally active controls. / 15.10.2020 / PubMed / Full text
Coronavirus Disease-2019 Conundrum: RAS Blockade and Geriatric-Associated Neuropsychiatric Disorders. / 2020 / PubMed / Full text
Pregnancy Protects Hyperandrogenemic Female Rats From Postmenopausal Hypertension. / 09.2020 / PubMed / Full text
Heart failure is associated with accelerated age related metabolic bone disease. / 05.06.2020 / PubMed / Full text
Management of heart failure: an Italian national survey on fellows/specialists in geriatrics. / 10.2020 / PubMed / Full text
Angiotensin-Converting Enzyme (ACE) genetic variation and longevity in Peruvian older people: a cross-sectional study. / 05.2020 / PubMed / Full text
COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection? / 30.03.2020 / PubMed / Full text
[i]A[/i]ngiotensin Converting Enzyme Inhibitors [i]C[/i]ombined with [i]E[/i]xercise for Hypertensive [i]S[/i]eniors (The ACES Trial): Study Protocol of a Randomized Controlled Trial. / 2019 / PubMed / Full text
Vascular age. / Winter.2020 / PubMed
Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
The renin-angiotensin aldosterone system and osteoporosis: findings from the Women's Health Initiative. / 10.2019 / PubMed / Full text
Adverse Childhood Experiences and Telomere Length a Look Into the Heterogeneity of Findings-A Narrative Review. / 2019 / PubMed / Full text
Obesity and aging affects skeletal muscle renin-angiotensin system and myosin heavy chain proportions in pre-diabetic Zucker rats. / 08.2019 / PubMed / Full text
Lisinopril Preserves Physical Resilience and Extends Life Span in a Genotype-Specific Manner in Drosophila melanogaster. / 13.11.2019 / PubMed / Full text
Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study. / 14.05.2019 / PubMed / Full text
Identifying the lifetime cognitive and socioeconomic antecedents of cognitive state: seven decades of follow-up in a British birth cohort study. / 24.04.2019 / PubMed / Full text
Association between Adverse Childhood Experiences and Muscle Strength in Older Age. / 2019 / PubMed / Full text
Feasibility Trial Evaluation of a Peer Volunteering Active Aging Intervention: ACE (Active, Connected, Engaged). / 02.04.2020 / PubMed / Full text
Deletion Polymorphism of Angiotensin-Converting Enzyme Gene Is Associated with Low Muscle Mass in Elderly People in Jakarta, Indonesia. / 12.11.2018 / PubMed / Full text
The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature. / 01.08.2019 / PubMed / Full text
Newly manufactured Marukome MK-34-1 miso with angiotensin-converting enzyme inhibitory activity and its antihypertensive effects in genetic hypertensive rat models. / 06.2019 / PubMed / Full text
Impact of resilience on health in older adults: a cross-sectional analysis from the International Mobility in Aging Study (IMIAS). / 28.11.2018 / PubMed / Full text
Age-related impairment in Addenbrooke's cognitive examination revised scores in patients with amyotrophic lateral sclerosis. / 11.2018 / PubMed / Full text
The Edinburgh Cognitive and Behavioral ALS screen: relationship to age, education, IQ and the Addenbrooke's Cognitive Examination-III. / 11.2018 / PubMed / Full text
Age- and Genotype-Specific Effects of the Angiotensin-Converting Enzyme Inhibitor Lisinopril on Mitochondrial and Metabolic Parameters in [i]Drosophila melanogaster[/i]. / 26.10.2018 / PubMed / Full text
Relevance of TSH evaluation in elderly in-patients with non-thyroidal illness. / 06.2019 / PubMed / Full text
Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study. / 2018 / PubMed / Full text
The Use of Mobile Games to Assess Cognitive Function of Elderly with and without Cognitive Impairment. / 2018 / PubMed / Full text
Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. / 10.2018 / PubMed / Full text
Onset Time of Inhibition of Return Is a Promising Index for Assessing Cognitive Functions in Older Adults. / 09.03.2020 / PubMed / Full text
Improving the comprehension of sarcopenic state determinants: An multivariate approach involving hormonal, nutritional, lifestyle and genetic variables. / 07.2018 / PubMed / Full text
Neuroticism predicts all-cause mortality over 19-years: The moderating effects on functional status, and the angiotensin-converting enzyme. / 07.2018 / PubMed / Full text
Adverse Childhood Experiences among a Community of Resilient Centenarians and Seniors: Implications for a Chronic Disease Prevention Framework. / 2018 / PubMed / Full text
Adverse Childhood Experiences and Young Adult Health Outcomes Among Youth Aging Out of Foster Care. / 07.2018 / PubMed / Full text
Sex differences in transcriptomic profiles in aged kidney cells of renin lineage. / 18.04.2018 / PubMed / Full text
The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system. / 03.2018 / PubMed / Full text
Comorbidity scores associated with limited life expectancy in the very elderly with nonmelanoma skin cancer. / 06.2018 / PubMed / Full text
Changes in prescription patterns in older hospitalized patients: the impact of FORTA on disease-related over- and under-treatments. / 03.2018 / PubMed / Full text
Relationship of quadriceps muscle power and optimal shortening velocity with angiotensin-converting enzyme activity in older women. / 2017 / PubMed / Full text
Effects of different antihypertensive medication groups on cognitive function in older patients: A systematic review. / 10.2017 / PubMed / Full text
The Test Your Memory for Mild Cognitive Impairment (TYM-MCI). / 12.2017 / PubMed / Full text
Life Course Pathways From Adverse Childhood Experiences to Adult Physical Health: A Structural Equation Model. / 02.2019 / PubMed / Full text
Frequent Sexual Activity Predicts Specific Cognitive Abilities in Older Adults. / 01.01.2019 / PubMed / Full text
Sex differences in the aging pattern of renin-angiotensin system serum peptidases. / 2017 / PubMed / Full text
STOPPFrail (Screening Tool of Older Persons Prescriptions in Frail adults with limited life expectancy): consensus validation. / 01.07.2017 / PubMed / Full text
Age differences in arterial and venous extra-cerebral blood flow in healthy adults: contributions of vascular risk factors and genetic variants. / 08.2017 / PubMed / Full text
Participant and Public Involvement in Refining a Peer-Volunteering Active Aging Intervention: Project ACE (Active, Connected, Engaged). / 19.03.2018 / PubMed / Full text
Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review. / 22.11.2016 / PubMed / Full text
Chymase-dependent production of angiotensin II: an old enzyme in old hearts. / 01.02.2017 / PubMed / Full text
Type 1 diabetes in older adults: Comparing treatments and chronic complications in the United States T1D Exchange and the German/Austrian DPV registries. / 12.2016 / PubMed / Full text
Association of adverse childhood experiences with lifetime mental and substance use disorders among men and women aged 50 years. / 03.2017 / PubMed / Full text
Bioactive peptides in beef: Endogenous generation through postmortem aging. / 01.2017 / PubMed / Full text
Angiotensin-Converting Enzyme Inhibitors and Parameters of Sarcopenia: Relation to Muscle Mass, Strength and Function: Data from the Berlin Aging Study-II (BASE-II). / 11.2016 / PubMed / Full text
Combined statin and angiotensin-converting enzyme (ACE) inhibitor treatment increases the lifespan of long-lived F1 male mice. / 12.2016 / PubMed / Full text
Establishing in-hospital geriatrics services in Africa: Insights from the University of Benin Teaching Hospital geriatrics project. / 07-09.2016 / PubMed / Full text
Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice. / 2016 / PubMed / Full text
Perindoprilat changes ANG (1-9) production in renal arteries isolated from young spontaneously hypertensive rats after ANG I incubation. / 08.11.2016 / PubMed / Full text
No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes. / 06.2016 / PubMed / Full text
Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span. / 02.2016 / PubMed / Full text
Risk Factors for Cardiovascular Disease in Type 1 Diabetes. / 05.2016 / PubMed / Full text
The Redox-sensitive Induction of the Local Angiotensin System Promotes Both Premature and Replicative Endothelial Senescence: Preventive Effect of a Standardized Crataegus Extract. / 12.2016 / PubMed / Full text
Adverse Childhood Experiences and Alcohol Consumption in Midlife and Early Old-Age. / 05.2016 / PubMed / Full text
Validation of the Spanish Version of the Face Name Associative Memory Exam (S-FNAME) in Cognitively Normal Older Individuals. / 11.2015 / PubMed / Full text
Frailty Syndrome: A Review. / 11.2014 / PubMed
Genetic influences on resting-state functional networks: A twin study. / 10.2015 / PubMed / Full text
Dysglycemia and Cognitive Dysfunction and Ill Health in People With High CV Risk: Results From the ONTARGET/TRANSCEND Studies. / 07.2015 / PubMed / Full text
In vivo visualization of the antialbuminuric effects of the angiotensin-converting enzyme inhibitor enalapril. / 05.2015 / PubMed / Full text
Embodiment effects and language comprehension in Alzheimer's disease. / 07.2015 / PubMed / Full text
ACE polymorphism and use of ACE inhibitors: effects on memory performance. / 06.2014 / PubMed / Full text
ACE inhibitors, statins and thiazides: no association with change in grip strength among community dwelling older men and women from the Hertfordshire Cohort Study. / 09.2014 / PubMed / Full text
Genetic influence on exercise-induced changes in physical function among mobility-limited older adults. / 01.03.2014 / PubMed / Full text
Age-related differences in the effect of psychological distress on mortality: Type D personality in younger versus older patients with cardiac arrhythmias. / 2013 / PubMed / Full text
Medications affecting functional status in older persons. / 2014 / PubMed / Full text
The ACE DD genotype and D-allele are associated with exceptional longevity: a meta-analysis. / 09.2013 / PubMed / Full text
Aβ43 is the earliest-depositing Aβ species in APP transgenic mouse brain and is converted to Aβ41 by two active domains of ACE. / 06.2013 / PubMed / Full text
Propofol increases vascular relaxation in aging rats chronically treated with the angiotensin-converting enzyme inhibitor captopril. / 04.2013 / PubMed / Full text
Identification of RAS genotypes that modulate blood pressure change by outdoor temperature. / 06.2013 / PubMed / Full text
The frequency of 4 common gene polymorphisms in nonagenarians, centenarians, and average life span individuals. / 03.2014 / PubMed / Full text
Effects of taxifolin on the activity of angiotensin-converting enzyme and reactive oxygen and nitrogen species in the aorta of aging rats and rats treated with the nitric oxide synthase inhibitor and dexamethasone. / 12.2013 / PubMed / Full text

SCD[править]

Cognitive training and brain stimulation in prodromal Alzheimer's disease (AD-Stim)-study protocol for a double-blind randomized controlled phase IIb (monocenter) trial. / 07.11.2020 / PubMed / Full text
Blood Pressure in Different Dementia Disorders, Mild Cognitive Impairment, and Subjective Cognitive Decline. / 2020 / PubMed / Full text
Known-Groups and Convergent Validity of the Telephone Rey Auditory Verbal Learning Test total Learning Scores for Distinguishing Between Older Adults With Amnestic Cognitive Impairment and Subjective Cognitive Decline. / 17.10.2020 / PubMed / Full text
Subjective cognitive decline as a predictor of future cognitive decline: a systematic review. / 07-09.2020 / PubMed / Full text
Geriatric assessment for older adults with sickle cell disease: protocol for a prospective cohort pilot study. / 2020 / PubMed / Full text
Prevalence and psychosocial correlates of subjectively perceived decline in five cognitive domains: Results from a population-based cohort study in Germany. / 08.06.2020 / PubMed / Full text
SC411 treatment can enhance survival in a mouse model of sickle cell disease. / 07.2020 / PubMed / Full text
DNA fragmentation of human spermatozoa: Simple assessment of single- and double-strand DNA breaks and their respective dynamic behavioral response. / 09.2020 / PubMed / Full text
Psychometric Cognitive Decline Precedes the Advent of Subjective Cognitive Decline in the Evolution of Alzheimer's Disease. / 2020 / PubMed / Full text
miR-1468-3p Promotes Aging-Related Cardiac Fibrosis. / 05.06.2020 / PubMed / Full text
Serum alkaline phosphatase is elevated and inversely correlated with cognitive functions in subjective cognitive decline: results from the ReGAl 2.0 project. / 03.05.2020 / PubMed / Full text
Myocardial cathepsin D is downregulated in sudden cardiac death. / 2020 / PubMed / Full text
Changes in Activity Participation Among Older Adults With Subjective Cognitive Decline or Objective Cognitive Deficits. / 2019 / PubMed / Full text
Age, gender and drug therapy influences on Tpeak-tend interval and on electrical risk score. / 03-04.2020 / PubMed / Full text
Comorbid Chronic Conditions Among Older Adults with Subjective Cognitive Decline, United States, 2015-2017. / 2020 / PubMed / Full text
Resting State BOLD Variability Is Linked to White Matter Vascular Burden in Healthy Aging but Not in Older Adults With Subjective Cognitive Decline. / 2019 / PubMed / Full text
Estimated Life Expectancy and Income of Patients With Sickle Cell Disease Compared With Those Without Sickle Cell Disease. / 01.11.2019 / PubMed / Full text
Does Empirically Derived Classification of Individuals with Subjective Cognitive Complaints Predict Dementia? / 07.11.2019 / PubMed / Full text
REMEDES for Alzheimer-R4Alz Battery: Design and Development of a New Tool of Cognitive Control Assessment for the Diagnosis of Minor and Major Neurocognitive Disorders. / 2019 / PubMed / Full text
Spatiotemporal Oscillatory Patterns During Working Memory Maintenance in Mild Cognitive Impairment and Subjective Cognitive Decline. / 01.2020 / PubMed / Full text
Microstructural Correlates and Laterality Effect of Prospective Memory in Non-Demented Adults with Memory Complaints. / 2019 / PubMed / Full text
Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis. / 2019 / PubMed / Full text
Multisensory, Multi-Tasking Performance of Older Adults With and Without Subjective Cognitive Decline. / 01.01.2019 / PubMed / Full text
Diffusion tensor imaging reveals abnormal brain networks in elderly subjects with subjective cognitive deficits. / 11.2019 / PubMed / Full text
Visual impairment in aging and cognitive decline: experience in a Memory Clinic. / 18.06.2019 / PubMed / Full text
Differences in Subjective Cognitive Complaints Between Non-Demented Older Adults from a Memory Clinic and the Community. / 2019 / PubMed / Full text
Frailty Is Related to Subjective Cognitive Decline in Older Women without Dementia. / 09.2019 / PubMed / Full text
Cognitive Function in Sickle Cell Disease Across Domains, Cerebral Infarct Status, and the Lifespan: A Meta-Analysis. / 01.09.2019 / PubMed / Full text
Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)-study protocol for a randomized controlled trial. / 01.05.2019 / PubMed / Full text
Subjective Cognitive Decline in the Community Is Affected at Multiple Aspects of Mental Health and Life Quality: A Cross-Sectional Study of the Community Medicine of Keelung Chang Gung Memorial Hospital. / 01-04.2019 / PubMed / Full text
Symptom clusters of subjective cognitive decline amongst cognitively normal older persons and their utilities in predicting objective cognitive performance: structural equation modelling. / 09.2019 / PubMed / Full text
State inequality, socioeconomic position and subjective cognitive decline in the United States. / 04.2019 / PubMed / Full text
Myocardial lipofuscin accumulation in ageing and sudden cardiac death. / 01.03.2019 / PubMed / Full text
Discriminating Alzheimer's disease progression using a new hippocampal marker from T1-weighted MRI: The local surface roughness. / 01.04.2019 / PubMed / Full text
Bone marrow neutrophil aging in sickle cell disease mice is associated with impaired osteoblast functions. / 12.2018 / PubMed / Full text
Subjective Cognitive Decline Prediction of Mortality: Results from the Einstein Aging Study. / 2018 / PubMed / Full text
Internal Consistency Over Time of Subjective Cognitive Decline: Drawing Preclinical Alzheimer's Disease Trajectories. / 2018 / PubMed / Full text
Callosal circularity as an early marker for Alzheimer's disease. / 2018 / PubMed / Full text
Subjective cognitive decline and risk of MCI: The Mayo Clinic Study of Aging. / 24.07.2018 / PubMed / Full text
Correlates of Subjective Cognitive Decline in Lesbian, Gay, Bisexual, and Transgender Older Adults. / 2018 / PubMed / Full text
Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice. / 29.05.2018 / PubMed / Full text
Sickle Cell Clinical Research and Intervention Program (SCCRIP): A lifespan cohort study for sickle cell disease progression from the pediatric stage into adulthood. / 09.2018 / PubMed / Full text
Subjective Cognitive Decline, Objective Cognition, and Depression in Older Hispanics Screened for Memory Impairment. / 2018 / PubMed / Full text
Comorbidities in aging patients with sickle cell disease. / 2018 / PubMed / Full text
Screening for cognitive impairment in an Australian aged care assessment team as part of comprehensive geriatric assessment. / 05.2019 / PubMed / Full text
Executive and Language Subjective Cognitive Decline Complaints Discriminate Preclinical Alzheimer's Disease from Normal Aging. / 2018 / PubMed / Full text
Identification of cytochrome b5 CYTB-5.1 and CYTB-5.2 in C. elegans; evidence for differential regulation of SCD. / 03.2018 / PubMed / Full text
Subjective Cognitive Decline Modifies the Relationship Between Cerebral Blood Flow and Memory Function in Cognitively Normal Older Adults. / 03.2018 / PubMed / Full text
Subjective cognitive decline and β-amyloid burden predict cognitive change in healthy elderly. / 07.11.2017 / PubMed / Full text
Subjective cognitive decline is longitudinally associated with lower health-related quality of life. / 12.2017 / PubMed / Full text
Altered Functional Connectivity in Sickle Cell Disease Exists at Rest and During Acute Pain Challenge. / 12.2017 / PubMed / Full text
Sickle cell disease in the older adult. / 01.2017 / PubMed / Full text
Executive functions and linguistic performance in SCD older adults and healthy controls. / 11.2017 / PubMed / Full text
Newborn screening and prophylactic interventions for sickle cell disease in 47 countries in sub-Saharan Africa: a cost-effectiveness analysis. / 26.07.2016 / PubMed / Full text
Incident Subjective Cognitive Decline Does Not Predict Mortality in the Elderly--Results from the Longitudinal German Study on Ageing, Cognition, and Dementia (AgeCoDe). / 2016 / PubMed / Full text
Cognitive and behavior deficits in sickle cell mice are associated with profound neuropathologic changes in hippocampus and cerebellum. / 01.2016 / PubMed / Full text
Informants' Perception of Subjective Cognitive Decline Helps to Discriminate Preclinical Alzheimer's Disease from Normal Aging. / 24.09.2015 / PubMed / Full text
Ascertaining Subjective Cognitive Decline: A Comparison of Approaches and Evidence for Using an Age-Anchored Reference Group. / 24.09.2015 / PubMed / Full text
Mortality in Individuals with Subjective Cognitive Decline: Results of the Leipzig Longitudinal Study of the Aged (LEILA75 ). / 24.09.2015 / PubMed / Full text
Targeting Cognitive Frailty: Clinical and Neurobiological Roadmap for a Single Complex Phenotype. / 2015 / PubMed / Full text
Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies. / 24.09.2015 / PubMed / Full text
Influence of Sampling and Recruitment Methods in Studies of Subjective Cognitive Decline. / 24.09.2015 / PubMed / Full text
Intellectual and physical activities, but not social activities, are associated with better global cognition: a multi-site evaluation of the cognition and lifestyle activity study for seniors in Asia (CLASSA). / 09.2015 / PubMed / Full text
Dose-dependent effect of androgen deprivation therapy for localized prostate cancer on adverse cardiac events. / 08.2016 / PubMed / Full text
The impact of subjective cognitive decline on Iowa Gambling Task performance. / 11.2015 / PubMed / Full text
Bovine brain region-specific stearoyl-CoA desaturase expression and fatty acid composition. / 06.2015 / PubMed / Full text
A biopsychosocial model for the management of patients with sickle-cell disease transitioning to adult medical care. / 04.2015 / PubMed / Full text
Health related quality of life and perception of stigmatisation in adolescents living with sickle cell disease in Nigeria: A cross sectional study. / 07.2015 / PubMed / Full text
Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53. / 03.2015 / PubMed / Full text
Cognitive frailty, a novel target for the prevention of elderly dependency. / 03.2015 / PubMed / Full text
Attention capacity and self-report of subjective cognitive decline: a P3 ERP study. / 12.2014 / PubMed / Full text
Cold hypersensitivity increases with age in mice with sickle cell disease. / 12.2014 / PubMed / Full text
Postural stability of older female Scottish country dancers in comparison with physically active controls. / 01.2015 / PubMed / Full text
Cancer death is related to high palmitoleic acid in serum and to polymorphisms in the SCD-1 gene in healthy Swedish men. / 03.2014 / PubMed / Full text
An update on the recent literature on sickle cell bone disease. / 12.2013 / PubMed / Full text
Use of interrupted time-series method to evaluate the impact of cigarette excise tax increases in Pennsylvania, 2000-2009. / 03.10.2013 / PubMed / Full text
Weight-based determination of spinal canal depth for paediatric lumbar punctures. / 11.2013 / PubMed / Full text
Birth month and longevity: birth month of victims of sudden (SCD, ≤1 h) and rapid (RCD, ≤24 h) cardiac deaths. / 2013 / PubMed / Full text
Transcriptomics of cortical gray matter thickness decline during normal aging. / 15.11.2013 / PubMed / Full text
Discrete event simulation model of sudden cardiac death predicts high impact of preventive interventions. / 2013 / PubMed / Full text

Aging genes 80-89

AR[править]

CP[править]

PTEN[править]

SIRT6[править]

TLR4[править]

CGA[править]

ACE[править]

SCD[править]

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