Aging genes 1-2

SMS

Does a Live Performance Impact Synchronization to Musical Rhythm in Cognitively Impaired Elderly? / 2020 / PubMed / Full text
Testing the effectiveness of physical activity advice delivered via text messaging vs. human phone advisors in a Latino population: The On The Move randomized controlled trial design and methods. / 08.2020 / PubMed / Full text

GPX4

l-carnitine supplementation during in vitro culture regulates oxidative stress in embryos from bovine aged oocytes. / 02.2020 / PubMed / Full text
Dietary Selenium Supplementation Ameliorates Female Reproductive Efficiency in Aging Mice. / 11.12.2019 / PubMed / Full text

IGFBP3

Cellular and Molecular Biomarkers Indicate Premature Aging in Pseudoxanthoma Elasticum Patients. / 05.2020 / PubMed / Full text
Paracrine senescence of human endometrial mesenchymal stem cells: a role for the insulin-like growth factor binding protein 3. / 17.01.2020 / PubMed / Full text

IQGAP1

IQGAP1-dysfunction leads to induction of senescence in human vascular smooth muscle cells. / 09.2020 / PubMed / Full text
Hyaluronan-binding protein 1 (HABP1) overexpression triggers induction of senescence in fibroblasts cells. / 06.2020 / PubMed / Full text

TLR1

Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. / 01.12.2020 / PubMed / Full text
Association of TLR gene variants in a Czech Red Pied cattle population with reproductive traits. / 02.2020 / PubMed / Full text

MPI

Age-related decline of lymphatic drainage from the eye: A noninvasive in vivo photoacoustic tomography study. / 05.2020 / PubMed / Full text
Interest of the multidimensional prognostic index (MPI) as an assessment tool in hospitalized patients in geriatrics. / 01.12.2019 / PubMed / Full text

EPO

Regulation of muscle and metabolic physiology by hypothalamic erythropoietin independently of its peripheral action. / 02.2020 / PubMed / Full text
Red Blood Cell Lifespan Shortening in Patients with Early-Stage Chronic Kidney Disease. / 2019 / PubMed / Full text

CXCR2

CXCL5-CXCR2 signaling is a senescence-associated secretory phenotype in preimplantation embryos. / 10.2020 / PubMed / Full text
Senescence in Wound Repair: Emerging Strategies to Target Chronic Healing Wounds. / 2020 / PubMed / Full text

TLR2

Changes in salivary microbial sensing proteins CD14 and TLR2 with aging. / 07.2020 / PubMed / Full text
Culture Model for Non-human Primate Choroid Plexus. / 2019 / PubMed / Full text

AHR

Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging. / 01.09.2020 / PubMed / Full text
Role of the Aryl Hydrocarbon Receptor in Environmentally Induced Skin Aging and Skin Carcinogenesis. / 28.11.2019 / PubMed / Full text

C6

Evolution of the Aroma of Treixadura Wines during Bottle Aging. / 08.10.2020 / PubMed / Full text
D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway. / 29.09.2020 / PubMed / Full text

HMGA2

4D Genome Rewiring during Oncogene-Induced and Replicative Senescence. / 07.05.2020 / PubMed / Full text
The protective effects of HMGA2 in the senescence process of bone marrow-derived mesenchymal stromal cells. / 04.2020 / PubMed / Full text

BACE1

Electric Stimulation of Neurogenesis Improves Behavioral Recovery After Focal Ischemia in Aged Rats. / 2020 / PubMed / Full text
Disruption of synaptic expression pattern and age-related DNA oxidation in a neuronal model of lead-induced toxicity. / 05.2020 / PubMed / Full text

C2

[Effects of resistance training on mitochondrial function in skeletal muscle of aging rats]. / 03.2020 / PubMed / Full text
Structural and functional characterization of Solanum lycopersicum phosphatidylinositol 3-kinase C2 domain. / 03.2020 / PubMed / Full text

CYP2C19

Physiologically Based Pharmacokinetic Approach Can Successfully Predict Pharmacokinetics of Citalopram in Different Patient Populations. / 04.2020 / PubMed / Full text
Longitudinal exposure of English primary care patients to pharmacogenomic drugs: An analysis to inform design of pre-emptive pharmacogenomic testing. / 12.2019 / PubMed / Full text

SDC1

Olmesartan alleviates bleomycin-mediated vascular smooth muscle cell senescence via the miR-665/SDC1 axis. / 2020 / PubMed / Full text
Sulfated syndecan 1 is critical to preventing cellular senescence by modulating fibroblast growth factor receptor endocytosis. / 08.2020 / PubMed / Full text

C5

The C5-75 Program: Meeting the Need for Efficient, Pragmatic Frailty Screening and Management in Primary Care. / 23.06.2020 / PubMed / Full text
Can a relatively large spinal cord for the dural sac influence severity of paralysis in elderly patients with cervical spinal cord injury caused by minor trauma? / 26.06.2020 / PubMed / Full text

MME

Geriatric Opioid Harm Reduction: Interprofessional Student Learning Outcomes. / 01-12.2020 / PubMed / Full text
Effectiveness of local anesthetic injection in geriatric patients following operative management of proximal and diaphyseal femur fracture. / 11.2019 / PubMed / Full text

DRD2

Cortical thickness mediates the relationship between DRD2 C957T polymorphism and executive function across the adult lifespan. / 11.11.2020 / PubMed / Full text
The relationship of age and DRD2 polymorphisms to frontostriatal brain activity and working memory performance. / 12.2019 / PubMed / Full text

LPL

Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects. / 09.2020 / PubMed / Full text
Influence of common health disorders on the length of productive life and stayability in German Holstein cows. / 01.2020 / PubMed / Full text

ELOVL2

ELOVL2: Not just a biomarker of aging. / 2020 / PubMed / Full text
The lipid elongation enzyme ELOVL2 is a molecular regulator of aging in the retina. / 02.2020 / PubMed / Full text

CSF1R

CSF1R inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice. / 02.02.2020 / PubMed / Full text
Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units. / 05.11.2019 / PubMed / Full text

PML

Progressive multifocal leukoencephalopathy in dimethyl fumarate-treated multiple sclerosis patients. / 18.08.2020 / PubMed / Full text
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson-Gilford progeria syndrome. / 06.2020 / PubMed / Full text

FSHR

FSHR ablation induces depression-like behaviors. / 08.2020 / PubMed / Full text
Direct actions of gonadotropins beyond the reproductive system and their role in human aging and neoplasia [Bezpośrednie działanie gonadotropin poza układem rozrodczym i ich rola w starzeniu się i nowotworzeniu u człowieka]. / 2019 / PubMed / Full text

E2F1

Regulation of E2F1 activity via PKA-mediated phosphorylations. / 2020 / PubMed / Full text
Astragaloside IV ameliorates radiation-induced senescence via antioxidative mechanism. / 08.2020 / PubMed / Full text

MBP

Demyelination associated with chronic arsenic exposure in Wistar rats. / 15.04.2020 / PubMed / Full text
Natural killer cells as participants in pathogenesis of rat experimental autoimmune encephalomyelitis (EAE): lessons from research on rats with distinct age and strain. / 2019 / PubMed / Full text

ABCG2

Contribution of senescence in human endometrial stromal cells during proliferative phase to embryo receptivity†. / 23.06.2020 / PubMed / Full text
ABCG2 rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population. / 17.03.2020 / PubMed / Full text

SPARC

SPARC Metrics Provide Mobility Smoothness Assessment in Oldest-Old With and Without a History of Falls: A Case Control Study. / 2020 / PubMed / Full text
Reduced fibrillar collagen accumulation in skeletal muscle of secreted protein acidic and rich in cysteine (SPARC)-null mice. / 29.11.2019 / PubMed / Full text

LTA

Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice. / 02.2020 / PubMed / Full text
The change of pain classes over time: a latent transition analysis. / 02.2020 / PubMed / Full text

ERG

Effect of age and sex on neurodevelopment and neurodegeneration in the healthy eye: Longitudinal functional and structural study in the Long-Evans rat. / 11.2020 / PubMed / Full text
Mice With a Combined Deficiency of Superoxide Dismutase 1 (Sod1), DJ-1 (Park7), and Parkin (Prkn) Develop Spontaneous Retinal Degeneration With Aging. / 03.09.2019 / PubMed / Full text

NPR1

The NPR1-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana. / 03.12.2020 / PubMed / Full text
Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis. / 07.2020 / PubMed / Full text

LEP

Age- and Sex-Specific Changes in Lower-Limb Muscle Power Throughout the Lifespan. / 18.06.2020 / PubMed / Full text
The Copenhagen Sarcopenia Study: lean mass, strength, power, and physical function in a Danish cohort aged 20-93 years. / 12.2019 / PubMed / Full text

POT1

MiR-185 targets POT1 to induce telomere dysfunction and cellular senescence. / 18.07.2020 / PubMed / Full text
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence. / 2019 / PubMed / Full text

FGA

Goal Pursuit, Goal Adjustment, and Pain in Middle-Aged Adults Aging With Physical Disability. / 12.2019 / PubMed / Full text
Tenacious Goal Pursuit, Flexible Goal Adjustment, and Life Satisfaction Among Chinese Older Adult Couples. / 01.2020 / PubMed / Full text

SYK

miR-25-3p promotes endothelial cell angiogenesis in aging mice via TULA-2/SYK/VEGFR-2 downregulation. / 17.11.2020 / PubMed / Full text
Identification of SYK inhibitor, R406 as a novel senolytic agent. / 07.05.2020 / PubMed / Full text

NNT

Yoga, Health-Related Quality of Life and Mental Well-Being: A Re-analysis of a Meta-analysis Using the Quality Effects Model. / 16.09.2020 / PubMed / Full text
Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database. / 02.2020 / PubMed / Full text

VDAC1

Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian longevity. / 07.2020 / PubMed / Full text
Changes in the expression of oxidative phosphorylation complexes in the aging intestinal mucosa. / 01.07.2020 / PubMed / Full text

LSS

Surgical results in older patients with lumbar spinal stenosis according to gait speed in relation to the diagnosis for sarcopenia. / 01-04.2020 / PubMed / Full text
Streamlining an existing hip fracture patient pathway in an acute tertiary adult Irish hospital to improve patient experience and outcomes. / 22.12.2019 / PubMed / Full text

OGT

ELT-2 promotes O-GlcNAc transferase OGT-1 expression to modulate Caenorhabditis elegans lifespan. / 06.07.2020 / PubMed / Full text
Neuronal O-GlcNAcylation Improves Cognitive Function in the Aged Mouse Brain. / 21.10.2019 / PubMed / Full text

VIP

Alterations in Intrinsic and Synaptic Properties of Hippocampal CA1 VIP Interneurons During Aging. / 2020 / PubMed / Full text
Nutrition and exercise interventions could ameliorate age-related cognitive decline: a meta-analysis of randomized controlled trials. / 14.10.2020 / PubMed / Full text

CX3CR1

Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism. / 04.2020 / PubMed / Full text
Muscle Injury Induces Postoperative Cognitive Dysfunction. / 17.02.2020 / PubMed / Full text

CDA

Cumulative Dis/Advantage and Health Pattern in Late Life: A Comparison between Genders and Welfare State Regimes. / 2019 / PubMed / Full text
Does numerical similarity alter age-related distractibility in working memory? / 2019 / PubMed / Full text

DCX

GSK-3β activation accelerates early-stage consumption of Hippocampal Neurogenesis in senescent mice. / 2020 / PubMed / Full text
Doublecortin and IGF-1R protein levels are reduced in spite of unchanged DNA methylation in the hippocampus of aged rats. / 04.2020 / PubMed / Full text

MCU

A rare case of Epstein-Barr virus-positive mucocutaneous ulcer that developed into an intestinal obstruction: a case report. / 13.01.2020 / PubMed / Full text
Inhibition of Mitochondrial Calcium Overload by SIRT3 Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue. / 02.2020 / PubMed / Full text

BAX

Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-X -BAX interaction. / 10.2020 / PubMed / Full text
CREB Signaling Mediates Dose-Dependent Radiation Response in the Murine Hippocampus Two Years after Total Body Exposure. / 03.01.2020 / PubMed / Full text

HMGCR

Cholesterol Homeostasis: An In Silico Investigation into How Aging Disrupts Its Key Hepatic Regulatory Mechanisms. / 30.09.2020 / PubMed / Full text
Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence. / 01.2020 / PubMed / Full text

CBS

Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity. / 02.08.2020 / PubMed / Full text
Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase. / 06.2020 / PubMed / Full text

CDK4

Emerging Roles for the [i]INK4a/ARF[/i] ([i]CDKN2A[/i]) Locus in Adipose Tissue: Implications for Obesity and Type 2 Diabetes. / 22.09.2020 / PubMed / Full text
Guilu Erxian Glue () Inhibits Chemotherapy-Induced Bone Marrow Hematopoietic Stem Cell Senescence in Mice May via p16 -Rb Signaling Pathway. / 11.2020 / PubMed / Full text

BPI

High TARC plasma levels confer protection to long living individuals by inducing M2 profile. / 01.2021 / PubMed / Full text
Circulating BPIFB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals. / 2020 / PubMed / Full text

PDK1

Inhibition of 3-phosphoinositide-dependent protein kinase 1 (PDK1) can revert cellular senescence in human dermal fibroblasts. / 08.12.2020 / PubMed / Full text
The Impact of the PI3K/Akt Signaling Pathway in Anxiety and Working Memory in Young and Middle-Aged PDK1 K465E Knock-In Mice. / 2020 / PubMed / Full text

CR1

Single Nucleotide Polymorphisms in Alzheimer's Disease Risk Genes Are Associated with Intrinsic Connectivity in Middle Age. / 2020 / PubMed / Full text
The whale shark genome reveals how genomic and physiological properties scale with body size. / 25.08.2020 / PubMed / Full text

NPY

Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells. / 22.05.2020 / PubMed / Full text
Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice. / 03.2020 / PubMed / Full text

HRAS

How do combinations of unhealthy behaviors relate to attitudinal factors and subjective health among the adult population in the Netherlands? / 03.04.2020 / PubMed / Full text
Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype. / 07.02.2020 / PubMed / Full text

GRN

Stressful development: Integrating endoderm development, stress, and longevity. / 08.12.2020 / PubMed / Full text
A Scoping Review of the Evidence About the Nurses Improving Care for Healthsystem Elders (NICHE) Program. / 04.11.2019 / PubMed / Full text

TRPV4

TRPV4 receptor as a functional sensory molecule in bladder urothelium: Stretch-independent, tissue-specific actions and pathological implications. / 01.2020 / PubMed / Full text
Exercise restores impaired endothelium-derived hyperpolarizing factor-mediated vasodilation in aged rat aortic arteries via the TRPV4-K 2.3 signaling complex. / 2019 / PubMed / Full text

PTH

Vitamin D Receptor Polymorphisms in Sex-Frailty Paradox. / 05.09.2020 / PubMed / Full text
Parathyroid hormone ameliorates temporomandibular joint osteoarthritic-like changes related to age. / 04.2020 / PubMed / Full text

KRAS

Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging. / 09.2020 / PubMed
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. / 16.04.2020 / PubMed / Full text

CIT

Effect of sex on aging-related decline of dopamine transporter in healthy subjects. / 14.10.2020 / PubMed / Full text
The Relationship Between the Striatal Dopaminergic Neuronal and Cognitive Function With Aging. / 2020 / PubMed / Full text

RIPK1

Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. / 18.11.2020 / PubMed / Full text
Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. / 05.2020 / PubMed / Full text

PCSK9

Lipoprotein removal mechanisms and aging: implications for the cardiovascular health of the elderly. / 04.2020 / PubMed / Full text
The role of proprotein convertase subtilisin-kexin type 9 (PCSK9) in the vascular aging process - is there a link? / 10.2019 / PubMed / Full text

SPRY1

Sprouty1 Prevents Cellular Senescence Maintaining Proliferation and Differentiation Capacity of Human Adipose Stem/Progenitor Cells. / 13.11.2020 / PubMed / Full text
Mechanism of SPRY1 methylation regulating natural aging of skin epidermal cells. / 05.2020 / PubMed / Full text

TSPO

Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge. / 2019 / PubMed / Full text
Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study. / 10.11.2019 / PubMed / Full text

KLF4

Extracellular Vesicles from Healthy Cells Improves Cell Function and Stemness in Premature Senescent Stem Cells by miR-302b and HIF-1α Activation. / 25.06.2020 / PubMed / Full text
Soluble klotho regulates the function of salivary glands by activating KLF4 pathways. / 02.10.2019 / PubMed / Full text

INS

Melatonin protects INS-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity. / 03.07.2020 / PubMed / Full text
Nicotine triggers islet β cell senescence to facilitate the progression of type 2 diabetes. / 08.2020 / PubMed / Full text

SAG

WRKY42 transcription factor positively regulates leaf senescence through modulating SA and ROS synthesis in Arabidopsis thaliana. / 09.2020 / PubMed / Full text
Neurogenesis in the inner ear: the zebrafish statoacoustic ganglion provides new neurons from a Neurod/Nestin-positive progenitor pool well into adulthood. / 10.04.2020 / PubMed / Full text

JAK1

Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling. / 01.05.2020 / PubMed / Full text
The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Through JAK1. / 2019 / PubMed / Full text

F5

Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis. / 02.2020 / PubMed / Full text
Fermentation of Blackberry with [i]L. plantarum[/i] JBMI F5 Enhance the Protection Effect on UVB-Mediated Photoaging in Human Foreskin Fibroblast and Hairless Mice through Regulation of MAPK/NF-κB Signaling. / 11.10.2019 / PubMed / Full text

ACR

Progenitor cell niche senescence reflects pathology of the parotid salivary gland in primary Sjögren's syndrome. / 01.10.2020 / PubMed / Full text
Jumping Joints: The Complex Relationship Between Osteoarthritis and Jumping Mechanography. / 02.2020 / PubMed / Full text

TMPRSS2

Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants. / 09.09.2020 / PubMed / Full text
Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. / 03.06.2020 / PubMed / Full text

CXCL1

Contusion spinal cord injury upregulates p53 protein expression in rat soleus muscle at multiple timepoints but not key senescence cytokines. / 02.2020 / PubMed / Full text
Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy. / 2019 / PubMed / Full text

HP

A narrative review of highly processed food addiction across the lifespan. / 28.10.2020 / PubMed / Full text
Beta Human Papillomavirus 8E6 Attenuates LATS Phosphorylation after Failed Cytokinesis. / 01.06.2020 / PubMed / Full text

GATA4

Epigenetics and Vascular Senescence-Potential New Therapeutic Targets? / 2020 / PubMed / Full text
Prolonged treatment with Y-27632 promotes the senescence of primary human dermal fibroblasts by increasing the expression of IGFBP-5 and transforming them into a CAF-like phenotype. / 25.08.2020 / PubMed / Full text

ADM

Assessment of age-related differences in decomposition-based quantitative EMG in the intrinsic hand muscles: A multivariate approach. / 09.2020 / PubMed / Full text
Evaluation of transcriptional levels of the natriuretic peptides, endothelin-1, adrenomedullin, their receptors and long non-coding RNAs in rat cardiac tissue as cardiovascular biomarkers of aging. / 01.2020 / PubMed / Full text

CCN3

CCN3 Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta. / 2020 / PubMed / Full text
CCN3 (NOV) Drives Degradative Changes in Aging Articular Cartilage. / 13.10.2020 / PubMed / Full text

PSEN2

Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2. / 2020 / PubMed / Full text
Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition. / 03.2020 / PubMed / Full text

CPT1C

Carnitine palmitoyltransferase 1C reverses cellular senescence of MRC-5 fibroblasts via regulating lipid accumulation and mitochondrial function. / 02.2021 / PubMed / Full text
Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence. / 14.04.2020 / PubMed / Full text

CFTR

Exercise Physiology Across the Lifespan in Cystic Fibrosis. / 2019 / PubMed / Full text
Reduced expression of the Ion channel CFTR contributes to airspace enlargement as a consequence of aging and in response to cigarette smoke in mice. / 02.09.2019 / PubMed / Full text

HDAC3

Histone deacetylase-3: Friend and foe of the brain. / 07.2020 / PubMed / Full text
Loss of HDAC3 contributes to meiotic defects in aged oocytes. / 12.2019 / PubMed / Full text

FNDC5

Irisin Correlates Positively With BMD in a Cohort of Older Adult Patients and Downregulates the Senescent Marker p21 in Osteoblasts. / 14.10.2020 / PubMed / Full text
[Investigation of signal molecules in saliva: prospects of application for diagnostics of myocardial infarction and the aging rate of different age people.] / 2019 / PubMed

ABO

Allelic distribution of [i]ABO[/i] gene in Chinese centenarians. / 09.2020 / PubMed / Full text
Genetically Determined ABO Blood Group and its Associations With Health and Disease. / 03.2020 / PubMed / Full text

FGFR1

Alignment of Alzheimer's disease amyloid β-peptide and klotho. / 11-12.2020 / PubMed / Full text
Satellite cell-specific ablation of Cdon impairs integrin activation, FGF signalling, and muscle regeneration. / 08.2020 / PubMed / Full text

NOTCH1

[How Does Aging Contribute to Cancer?] / 09.2020 / PubMed
H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice. / 10.2019 / PubMed / Full text

SRF

Changes in snail and SRF expression in the kidneys of diabetic rats during ageing. / 01.2020 / PubMed / Full text
Mechanosensitive transcriptional coactivators MRTF-A and YAP/TAZ regulate nucleus pulposus cell phenotype through cell shape. / 12.2019 / PubMed / Full text

BPIFB4

New Insights for BPIFB4 in Cardiovascular Therapy. / 28.09.2020 / PubMed / Full text
LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice. / 28.08.2019 / PubMed / Full text

MALT1

MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. / 29.04.2020 / PubMed / Full text
MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging. / 2019 / PubMed / Full text

MFN2

Thioredoxin protects mitochondrial structure, function and biogenesis in myocardial ischemia-reperfusion via redox-dependent activation of AKT-CREB- PGC1α pathway in aged mice. / 13.10.2020 / PubMed / Full text
MFN2 contributes to metabolic disorders and inflammation in the aging of rat chondrocytes and osteoarthritis. / 08.2020 / PubMed / Full text

MMP1

Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts. / 12.2020 / PubMed / Full text
A novel multifunctional skin care formulation with a unique blend of antipollution, brightening and antiaging active complexes. / 06.2020 / PubMed / Full text

TBC1D5

TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry. / 09.06.2020 / PubMed / Full text
Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling. / 02.09.2019 / PubMed / Full text

ADAM10

NKG2D Ligand Shedding in Response to Stress: Role of ADAM10. / 2020 / PubMed / Full text
Chronic Mild Stress Modified Epigenetic Mechanisms Leading to Accelerated Senescence and Impaired Cognitive Performance in Mice. / 10.02.2020 / PubMed / Full text

PLK4

A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence. / 05.2020 / PubMed / Full text
Differential expression of AURKA/PLK4 in quiescence and senescence of osteosarcoma U2OS cells. / 04.2020 / PubMed / Full text

FAS

Five-year change in maximum tongue pressure and physical function in community-dwelling elderly adults. / 09.2020 / PubMed / Full text
Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity. / 03.2020 / PubMed / Full text

GAL

Overexpression of Pitx1 attenuates the senescence of chondrocytes from osteoarthritis degeneration cartilage-A self-controlled model for studying the etiology and treatment of osteoarthritis. / 02.2020 / PubMed / Full text
β-Caryophyllene Reduces DNA Oxidation and the Overexpression of Glial Fibrillary Acidic Protein in the Prefrontal Cortex and Hippocampus of d-Galactose-Induced Aged BALB/c Mice. / 05.2020 / PubMed / Full text

GCA

Familial aggregation of longevity in giant cell arteritis and polymyalgia rheumatica. / 12.2020 / PubMed / Full text
Interaction between Alcohol Consumption and Apolipoprotein E (ApoE) Genotype with Cognition in Middle-Aged Men. / 14.07.2020 / PubMed / Full text

PTX3

Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. / 27.01.2020 / PubMed / Full text
Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study. / 13.07.2020 / PubMed / Full text

MITF

Thymocid , a Standardized Black Cumin ([i]Nigella sativa[/i]) Seed Extract, Modulates Collagen Cross-Linking, Collagenase and Elastase Activities, and Melanogenesis in Murine B16F10 Melanoma Cells. / 19.07.2020 / PubMed / Full text
HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth. / 21.05.2020 / PubMed / Full text

KEAP1

NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands. / 09.2020 / PubMed / Full text
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds. / 18.05.2020 / PubMed / Full text

GAA

Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia. / 27.07.2020 / PubMed / Full text
Age-Related Changes in Serum Guanidinoacetic Acid in Women. / 30.12.2019 / PubMed / Full text

RHO

Conditional reprogramming: next generation cell culture. / 08.2020 / PubMed / Full text
SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells. / 18.05.2020 / PubMed / Full text

MIA

Age, cohort, and period effects on metamemory beliefs. / 12.2019 / PubMed / Full text
Memory Age-based Stereotype Threat: Role of Locus of Control and Anxiety. / 01-02.2020 / PubMed / Full text

GHRH

Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone. / 18.05.2020 / PubMed / Full text
Transcriptomic and metabolomic profiling of long-lived growth hormone releasing hormone knock-out mice: evidence for altered mitochondrial function and amino acid metabolism. / 23.02.2020 / PubMed / Full text

PIP

Potentially inappropriate prescriptions according to explicit and implicit criteria in patients with multimorbidity and polypharmacy. MULTIPAP: A cross-sectional study. / 2020 / PubMed / Full text
Quality of prescribing predicts hospitalisation in octogenarians: life and living in advanced age: a cohort study in New Zealand (LiLACS NZ). / 19.12.2019 / PubMed / Full text