Aging genes 30-59

TG

Inhibition of the alternative lengthening of telomeres pathway by subtelomeric sequences in Saccharomyces cerevisiae. / 12.2020 / PubMed / Full text
E4orf1, an Adeno-viral protein, attenuates renal lipid accumulation in high fat fed mice: A novel approach to reduce a key risk factor for chronic kidney disease. / 10.2020 / PubMed / Full text
Resistance exercise attenuates postprandial metabolic responses to a high-fat meal similarly in younger and older men. / 11.2020 / PubMed / Full text
Aging-induced aberrant RAGE/PPARα axis promotes hepatic steatosis via dysfunctional mitochondrial β oxidation. / 10.2020 / PubMed / Full text
Fenofibrate impairs liver function and structure more pronounced in old than young rats. / 27.08.2020 / PubMed / Full text
Awareness of major cardiovascular risk factors and its relationship with markers of vascular aging: Data from the Brisighella Heart Study. / 09.06.2020 / PubMed / Full text
Characterisation of the dynamic nature of lipids throughout the lifespan of genetically identical female and male Daphnia magna. / 27.03.2020 / PubMed / Full text
Effects of laboratory biotic aging on the characteristics of biochar and its water-soluble organic products. / 15.01.2020 / PubMed / Full text
Using Caenorhabditis elegans for Studying Trans- and Multi-Generational Effects of Toxicants. / 29.07.2019 / PubMed / Full text
Interaction between mitochondrial NADH dehydrogenase subunit-2 5178 C > A and clinical risk factors on the susceptibility of essential hypertension in Chinese population. / 05.07.2019 / PubMed / Full text
[Correlation between methylation level of [i]CDKN2A[/i] and [i]CDKN2B[/i] genes and aging in healthy individuals]. / 30.06.2019 / PubMed / Full text
The Effects of Age and Reproduction on the Lipidome of [i]Caenorhabditis elegans[/i]. / 2019 / PubMed / Full text
Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α-Synuclein and Polyglutamine in Aging [i]Caenorhabditis elegans[/i]. / 19.07.2019 / PubMed / Full text
Association between vitamin D status and glycemic profile in postmenopausal women with type 2 diabetes. / 05-06.2019 / PubMed / Full text
Negative Association of Serum URIC Acid with Peripheral Blood Cellular Aging Markers. / 2019 / PubMed / Full text
Improving Treatment of Elderly Patients by Interprofessional Education in a Quality Network of Geriatric Medicine: Protocol for Evaluating an Educational Initiative. / 03.05.2019 / PubMed / Full text
Hsp22 overexpression induces myocardial hypertrophy, senescence and reduced life span through enhanced oxidative stress. / 06.2019 / PubMed / Full text
Age-Related Diazinon Toxicity Impact on Blood Glucose, Lipid Profile and Selected Biochemical Indices in Male Rats. / 2019 / PubMed / Full text
Longevity-Associated Forkhead Box O3 (FOXO3) Single Nucleotide Polymorphisms are Associated with Type 2 Diabetes Mellitus in Chinese Elderly Women. / 22.04.2019 / PubMed / Full text
[The impact of lipid metabolism on the rate of aging of patients with arterial hypertension.] / 2018 / PubMed / Full text
Age, Sex, and Cardiovascular Risk Attributable to Lipoprotein Cholesterol Among Chinese Individuals with Coronary Artery Disease: A Case-Control Study. / 05.2019 / PubMed / Full text
Trimetazidine and l‑carnitine prevent heart aging and cardiac metabolic impairment in rats via regulating cardiac metabolic substrates. / 05.2019 / PubMed / Full text
Plasma Response to Deuterium-Labeled Vitamin K Intake Varies by TG Response, but Not Age or Vitamin K Status, in Older and Younger Adults. / 01.01.2019 / PubMed / Full text
Moderate Aerobic Training Decreases Blood Pressure but No Other Cardiovascular Risk Factors in Hypertensive Overweight/Obese Elderly Patients. / 01-12.2018 / PubMed / Full text
Gender and Age Stratified Analyses of Nutrient and Dietary Pattern Associations with Circulating Lipid Levels Identify Novel Gender and Age-Specific Correlations. / 14.11.2018 / PubMed / Full text
Novel anti-aging gene NM_026333 contributes to proton-induced aging via NCX1-pathway. / 12.2018 / PubMed / Full text
Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background. / 10.10.2018 / PubMed / Full text
Effects of Ginsenoside Rg3 on fatigue resistance and SIRT1 in aged rats. / 01.11.2018 / PubMed / Full text
Intracellular protons accelerate aging and switch on aging hallmarks in mice. / 12.2018 / PubMed / Full text
Induction of miR-15a expression by tripterygium glycosides caused premature ovarian failure by suppressing the Hippo-YAP/TAZ signaling effector Lats1. / 15.12.2018 / PubMed / Full text
Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice. / 15.10.2018 / PubMed / Full text
Testosterone level in aging male with different glucose tolerance state and its association with osteocalcin. / 03.2019 / PubMed / Full text
The effects of 12-week progressive strength training on strength, functional capacity, metabolic biomarkers, and serum hormone concentrations in healthy older women: morning versus evening training. / 10.2018 / PubMed / Full text
L-Lysine Attenuates Hepatic Steatosis in Senescence-Accelerated Mouse Prone 8 Mice. / 2018 / PubMed / Full text
Evaluation of the Effect of the Sulcus Angle and Lateral to Medial Facet Ratio of the Patellar Groove on Patella Tracking in Aging Subjects with Stable Knee Joint. / 2018 / PubMed / Full text
Metabolic and inflammatory biomarkers are associated with epigenetic aging acceleration estimates in the GOLDN study. / 2018 / PubMed / Full text
Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. / 10.2018 / PubMed / Full text
[Dynamic changes of reproductive hormone levels and related factors in old and middleaged men in health examination]. / 02.2017 / PubMed
Sex Differences in Adipose Tissue CD8 T Cells and Regulatory T Cells in Middle-Aged Mice. / 2018 / PubMed / Full text
Morphological and functional changes in TRPM8-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice. / 01.08.2018 / PubMed / Full text
Mitochondrial inhibitory factor protein 1 attenuates coupling factor 6-induced aging signal. / 07.2018 / PubMed / Full text
Shifts in gut microbiota composition in an APP/PSS1 transgenic mouse model of Alzheimer's disease during lifespan. / 06.2018 / PubMed / Full text
Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks. / 05-06.2018 / PubMed / Full text
Association of regular walking and body mass index on metabolic syndrome among an elderly Korean population. / 06.2018 / PubMed / Full text
Activation of Grm1 expression by mutated BRaf (V600E) [i]in vitro[/i] and [i]in vivo[/i]. / 19.01.2018 / PubMed / Full text
Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2. / 10.2018 / PubMed / Full text
[Analysis of serum reproductive hormone levels in men with hyperlipemia in the urban area of Shijiazhuang]. / 11.2016 / PubMed
Effects of cognitive training based on metamemory and mental images. / 04-06.2010 / PubMed / Full text
Pioglitazone attenuates aging-related disorders in aged apolipoprotein E deficient mice. / 02.2018 / PubMed / Full text
[A perspective cohort study on influence factors of survival outcome among the elderly aged ≥80 years old from longevity areas in China]. / 06.11.2017 / PubMed / Full text
Macrophage overexpression of matrix metalloproteinase-9 in aged mice improves diastolic physiology and cardiac wound healing after myocardial infarction. / 01.02.2018 / PubMed / Full text
Transthyretin deposition promotes progression of osteoarthritis. / 12.2017 / PubMed / Full text
MicroRNA-210-mediated proliferation, survival, and angiogenesis promote cardiac repair post myocardial infarction in rodents. / 12.2017 / PubMed / Full text
Association of lipid peroxidation and antioxidant status with metabolic syndrome in Iranian healthy elderly women. / 10.2017 / PubMed / Full text
The antioxidative and anti-aging effects of acidic- and alkalic-extractable mycelium polysaccharides by Agrocybe aegerita (Brig.) Sing. / 01.2018 / PubMed / Full text

CS

Acute effect of bodyweight-based strength training on blood pressure of hypertensive older adults: A randomized crossover clinical trial. / 16.11.2020 / PubMed / Full text
Particle growth with photochemical age from new particle formation to haze in the winter of Beijing, China. / 20.01.2021 / PubMed / Full text
Effect of aging on stabilization of Cd and Ni by biochars and enzyme activities in a historically contaminated alkaline agricultural soil simulated with wet-dry and freeze-thaw cycling. / 27.10.2020 / PubMed / Full text
Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD signaling. / 09.11.2020 / PubMed / Full text
Vision Impairment and Participation in Cognitively Stimulating Activities: The Health ABC Study. / 25.07.2020 / PubMed / Full text
Suspension training vs. traditional resistance training: effects on muscle mass, strength and functional performance in older adults. / 10.2020 / PubMed / Full text
Generational Differences in the 10-year Incidence of Impaired Contrast Sensitivity. / 21.07.2020 / PubMed / Full text
Inducible aging in Hydra oligactis implicates sexual reproduction, loss of stem cells, and genome maintenance as major pathways. / 08.2020 / PubMed / Full text
Noradrenergic Responsiveness Supports Selective Attention across the Adult Lifespan. / 27.05.2020 / PubMed / Full text
Cellular senescence: from anti-cancer weapon to anti-aging target. / 03.2020 / PubMed / Full text
Extra-mitochondrial citrate synthase initiates calcium oscillation and suppresses age-dependent sperm dysfunction. / 04.2020 / PubMed / Full text
Pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoke. / 10.2019 / PubMed / Full text
Possible Role of Amyloid Cross-Seeding in Evolvability and Neurodegenerative Disease. / 2019 / PubMed / Full text
Targeting p16-induced senescence prevents cigarette smoke-induced emphysema by promoting IGF1/Akt1 signaling in mice. / 2019 / PubMed / Full text
Theory of mind across lifespan from ages 16 to 81 years. / 11.2019 / PubMed / Full text
Antiproliferative effect of the histone demethylase inhibitor GSK-J4 in chondrosarcomas. / 11.2019 / PubMed / Full text
Nucleolar and Ribosomal Dysfunction-A Common Pathomechanism in Childhood Progerias? / 04.06.2019 / PubMed / Full text
Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation. / 2019 / PubMed / Full text
Wheat seed ageing viewed through the cellular redox environment and changes in pH. / 06.2019 / PubMed / Full text
c-Met as a new marker of cellular senescence. / 13.05.2019 / PubMed / Full text
Effects of UV-B radiation on the survival, egg hatchability and transcript expression of antioxidant enzymes in a high-temperature adapted strain of Neoseiulus barkeri. / 04.2019 / PubMed / Full text
[Kinetic model of aging biological species in natural habitat.] / 2018 / PubMed
[Reference values for the senior fitness test in Chilean older women]. / 12.2018 / PubMed / Full text
The optimal treatment for improving cognitive function in elder people with mild cognitive impairment incorporating Bayesian network meta-analysis and systematic review. / 05.2019 / PubMed / Full text
Recent Lifestyle Parameters Are Associated with Increasing Caesarean Section Rates among Singleton Term Births in Austria. / 21.12.2018 / PubMed / Full text
In vivo time-harmonic ultrasound elastography of the human brain detects acute cerebral stiffness changes induced by intracranial pressure variations. / 17.12.2018 / PubMed / Full text
Macular Inner Retinal Layer Thickness in Relation to Photopic and Mesopic Contrast Sensitivity in Healthy Young and Older Subjects. / 01.11.2018 / PubMed / Full text
Shortened Lifespan and Other Age-Related Defects in Bang Sensitive Mutants of [i]Drosophila melanogaster[/i]. / 10.12.2018 / PubMed / Full text
PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. / 03.2019 / PubMed / Full text
Vascular mitochondrial respiratory function: the impact of advancing age. / 01.12.2018 / PubMed / Full text
Impact of a shift work-like lighting schedule on the functioning of the circadian system in the short-lived fish Nothobranchius furzeri. / 02.10.2018 / PubMed / Full text
AGE-RELATED DETERIORATION OF BONE TOUGHNESS IS RELATED TO DIMINISHING AMOUNT OF MATRIX GLYCOSAMINOGLYCANS (GAGS). / 05.2018 / PubMed / Full text
Two Cockayne Syndrome patients with a novel splice site mutation - clinical and metabolic analyses. / 10.2018 / PubMed / Full text
High-speed resistance training in elderly women: Effects of cluster training sets on functional performance and quality of life. / 09.2018 / PubMed / Full text
Lung cellular senescence is independent of aging in a mouse model of COPD/emphysema. / 13.06.2018 / PubMed / Full text
In Vivo Analysis of the Climbing Fiber-Purkinje Cell Circuit in SCA2-58Q Transgenic Mouse Model. / 10.2018 / PubMed / Full text
Inpatient care expenditure of the elderly with chronic diseases who use public health insurance: Disparity in their last year of life. / 06.2018 / PubMed / Full text
Does Central Vision Loss Impair Visual Search Performance of Adults More than Children? / 05.2018 / PubMed / Full text
Genetic Ablation of p16 Does Not Protect against Cellular Senescence in Mouse Models of Chronic Obstructive Pulmonary Disease/Emphysema. / 08.2018 / PubMed / Full text
The adolescent idiopathic scoliotic IVD displays advanced aggrecanolysis and a glycosaminoglycan composition similar to that of aged human and ovine IVDs. / 09.2018 / PubMed / Full text
Mixed Neurodevelopmental and Neurodegenerative Pathology in [i]Nhe6[/i]-Null Mouse Model of Christianson Syndrome. / 11-12.2017 / PubMed / Full text
Persistent injury-associated anemia in aged rats. / 03.2018 / PubMed / Full text
The role of cellular senescence in aging through the prism of Koch-like criteria. / 01.2018 / PubMed / Full text
Acoustics of Clear and Noise-Adapted Speech in Children, Young, and Older Adults. / 09.11.2017 / PubMed / Full text
Sirt1 and Parp1 as epigenome safeguards and microRNAs as SASP-associated signals, in cellular senescence and aging. / 11.2017 / PubMed / Full text
The nuclear receptor and clock gene REV-ERBα regulates cigarette smoke-induced lung inflammation. / 02.12.2017 / PubMed / Full text
The effects of dexmedetomidine preconditioning on aged rat heart of ischaemia reperfusion injury. / 10.2017 / PubMed / Full text
Human Development Index (HDI) of the maternal country of origin as a predictor of perinatal outcomes - a longitudinal study conducted in Spain. / 21.09.2017 / PubMed / Full text
Flexural strength of fiber reinforced posts after mechanical aging by simulated chewing forces. / 01.2018 / PubMed / Full text
Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice. / 07.10.2017 / PubMed / Full text

PC

Blended home-based exercise and dietary protein in community-dwelling older adults: a cluster randomized controlled trial. / 26.10.2020 / PubMed / Full text
Right ventricular diastolic function in aging: a head-to-head comparison between phase-contrast MRI and Doppler echocardiography. / 27.09.2020 / PubMed / Full text
Pulse Width and Implantable Pulse Generator Longevity in Pallidal Deep Brain Stimulation for Dystonia: A Population-Based Comparative Effectiveness Study. / 2020 / PubMed / Full text
Gemcitabine plus nab-paclitaxel with initial dose reduction for older patients with advanced pancreatic cancer. / 20.06.2020 / PubMed / Full text
Protective effects of 17-β-oestradiol and phytoestrogen on age-induced oxidative stress and inhibition of surfactant synthesis in rat type II pneumocytes. / 02.2021 / PubMed / Full text
Pacing During 200-m Competitive Masters Swimming. / 07.2020 / PubMed / Full text
Prostate cancer in Pennsylvania: The role of older age at diagnosis, aggressiveness, and environmental risk factors on treatment and mortality using data from the Pennsylvania Cancer Registry. / 05.2020 / PubMed / Full text
Extracranial versus intracranial hydro-hemodynamics during aging: a PC-MRI pilot cross-sectional study. / 14.01.2020 / PubMed / Full text
Age-specific health-related quality of life in disease-free long-term prostate cancer survivors versus male population controls-results from a population-based study. / 06.2020 / PubMed / Full text
Cross-Linked Polyphenol-Based Drug Nano-Self-Assemblies Engineered to Blockade Prostate Cancer Senescence. / 23.10.2019 / PubMed / Full text
An Immersive Virtual Reality Platform for Assessing Spatial Navigation Memory in Predementia Screening: Feasibility and Usability Study. / 03.09.2019 / PubMed / Full text
Androgen deprivation therapy increases brain ageing. / 02.08.2019 / PubMed / Full text
Plasma Cells Are Obligate Effectors of Enhanced Myelopoiesis in Aging Bone Marrow. / 20.08.2019 / PubMed / Full text
Battery longevity of neurostimulators in Parkinson disease: A historic cohort study. / 07-08.2019 / PubMed / Full text
Dilated cardiomyopathy in 151 Irish Wolfhounds: Characteristic clinical findings, life expectancy and causes of death. / 03.2019 / PubMed / Full text
Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. / 06.02.2019 / PubMed / Full text
Profiling obesity phenotypes and trajectories in older adults of the Quebec NuAge cohort on nutrition and successful aging: A cluster analysis. / 04.2019 / PubMed / Full text
Long-term intake of phenolic compounds attenuates age-related cardiac remodeling. / 04.2019 / PubMed / Full text
Roles of Phenolic Compounds in the Reduction of Risk Factors of Cardiovascular Diseases. / 21.01.2019 / PubMed / Full text
Live imaging of angiogenesis during cutaneous wound healing in adult zebrafish. / 05.2019 / PubMed / Full text
Effects of Phase-Locking Deficits on Speech Recognition in Older Adults With Presbycusis. / 2018 / PubMed / Full text
The change of volume of the lumbar vertebrae along with aging in asymptomatic population: a preliminary analysis. / 2018 / PubMed
Epigenetic suppression of the anti-aging gene [i]KLOTHO[/i] in human prostate cancer cell lines. / 2017 / PubMed / Full text
Comparison of PC and iPad administrations of the Cogstate Brief Battery in the Mayo Clinic Study of Aging: Assessing cross-modality equivalence of computerized neuropsychological tests. / 08.2019 / PubMed / Full text
Evaluation of human mesenchymal stem cell senescence, differentiation and secretion behavior cultured on polycarbonate cell culture inserts. / 2018 / PubMed / Full text
Regional Differences in Palliative Care Utilization Among Geriatric Colorectal Cancer Patients Needing Emergent Surgery. / 01.2019 / PubMed / Full text
Age-Induced Spatial Memory Deficits in Rats Are Correlated with Specific Brain Region Alterations in Microglial Morphology and Gene Expression. / 06.2019 / PubMed / Full text
Age-related changes in mitochondrial membrane composition of Nothobranchius furzeri.: comparison with a longer-living Nothobranchius species. / 02.2019 / PubMed / Full text
Comparison between probabilistic and Wiener-Granger causality in assessing modifications of the cardiac baroreflex control with age. / 22.10.2018 / PubMed / Full text
Effect of CCNB1 silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer. / 01.2018 / PubMed / Full text
Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet. / 09.2018 / PubMed / Full text
The Use of Problem-Solving Therapy for Primary Care to Enhance Complex Decision-Making in Healthy Community-Dwelling Older Adults. / 2018 / PubMed / Full text
Battery Longevity Comparison of Two Commonly Available Dual Channel Implantable Pulse Generators Used for Subthalamic Nucleus Stimulation in Parkinson's Disease. / 2018 / PubMed / Full text
Identification of Phenolic Compounds-Rich Grape Pomace Extracts Urine Metabolites and Correlation with Gut Microbiota Modulation. / 04.06.2018 / PubMed / Full text
In Vivo Analysis of the Climbing Fiber-Purkinje Cell Circuit in SCA2-58Q Transgenic Mouse Model. / 10.2018 / PubMed / Full text
Effects of aging on serum levels of lipid molecular species as determined by lipidomics analysis in Japanese men and women. / 06.06.2018 / PubMed / Full text
Circular RNA expression and regulatory network prediction in posterior cingulate astrocytes in elderly subjects. / 09.05.2018 / PubMed / Full text
Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer. / 30.03.2018 / PubMed / Full text
Taurine supplementation induces long-term beneficial effects on glucose homeostasis in ob/ob mice. / 06.2018 / PubMed / Full text
Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood. / 06.2018 / PubMed / Full text
The relationships between physical capacity and biomechanical plasticity in old adults during level and incline walking. / 01.03.2018 / PubMed / Full text
Mixed Neurodevelopmental and Neurodegenerative Pathology in [i]Nhe6[/i]-Null Mouse Model of Christianson Syndrome. / 11-12.2017 / PubMed / Full text
The "Aging Factor" Eotaxin-1 (CCL11) Is Detectable in Transfusion Blood Products and Increases with the Donor's Age. / 2017 / PubMed / Full text
The Impact of Long-Term Intake of Phenolic Compounds-Rich Grape Pomace on Rat Gut Microbiota. / 01.2018 / PubMed / Full text
Whey protein concentrate supplementation protects rat brain against aging-induced oxidative stress and neurodegeneration. / 05.2018 / PubMed / Full text
In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers. / 04.2018 / PubMed / Full text
Pregnancy probabilistically augments potential precursors to chronic, immune-mediated or autoimmune lacrimal gland infiltrates. / 01.2018 / PubMed / Full text
Cerebellar pathology in childhood-onset vs. adult-onset essential tremor. / 17.10.2017 / PubMed / Full text
Potential Gender-Related Aging Processes Occur Earlier and Faster in the Vermis of Patients with Bipolar Disorder: An MRI Study. / 2017 / PubMed / Full text
Effects of Vitrectomy and Lensectomy on Older Rhesus Macaques: Oxygen Distribution, Antioxidant Status, and Aqueous Humor Dynamics. / 01.08.2017 / PubMed / Full text

APP

Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging. / 11.09.2020 / PubMed / Full text
Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD. / 09.07.2020 / PubMed / Full text
An agnostic reevaluation of the amyloid cascade hypothesis of Alzheimer's disease pathogenesis: The role of APP homeostasis. / 11.2020 / PubMed / Full text
Transcriptomic profiling of microglia and astrocytes throughout aging. / 01.04.2020 / PubMed / Full text
Platelets in Amyloidogenic Mice Are Activated and Invade the Brain. / 2020 / PubMed / Full text
CHIP modulates APP-induced autophagy-dependent pathological symptoms in Drosophila. / 02.2020 / PubMed / Full text
Studies on APP metabolism related to age-associated mitochondrial dysfunction in APP/PS1 transgenic mice. / 19.11.2019 / PubMed / Full text
Intermittent Hypoxia-Hyperoxia Training Improves Cognitive Function and Decreases Circulating Biomarkers of Alzheimer's Disease in Patients with Mild Cognitive Impairment: A Pilot Study. / 30.10.2019 / PubMed / Full text
The Implication of Androgens in the Presence of Protein Kinase C to Repair Alzheimer’s Disease-Induced Cognitive Dysfunction / 03.2020 / PubMed / Full text
Modulation of Neural and Muscular Adaptation Processes During Resistance Training by Fish Protein Ingestions in Older Adults. / 17.04.2020 / PubMed / Full text
Antipsychotic Polypharmacy in Older Adult Asian Patients With Schizophrenia: Research on Asian Psychotropic Prescription Pattern. / 11.2019 / PubMed / Full text
A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in the brain of Down syndrome patients. / 12.2019 / PubMed / Full text
Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. / 22.07.2019 / PubMed / Full text
The Age-Related Performance Decline in Marathon Running: The Paradigm of the Berlin Marathon. / 06.06.2019 / PubMed / Full text
The db mutation improves memory in younger mice in a model of Alzheimer's disease. / 01.09.2019 / PubMed / Full text
Electrophysiological Characterization of Networks and Single Cells in the Hippocampal Region of a Transgenic Rat Model of Alzheimer's Disease. / 01-02.2019 / PubMed / Full text
Age- and sex-dependent profiles of APP fragments and key secretases align with changes in despair-like behavior and cognition in young APPSwe/Ind mice. / 02.04.2019 / PubMed / Full text
Upregulation of Proteolytic Pathways and Altered Protein Biosynthesis Underlie Retinal Pathology in a Mouse Model of Alzheimer's Disease. / 09.2019 / PubMed / Full text
Soluble Amyloid Precursor Protein α: Friend or Foe? / 2018 / PubMed / Full text
Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity. / 08.2019 / PubMed / Full text
Selective reduction of APP-BACE1 activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PDAPP mice. / 03.2019 / PubMed / Full text
Effect of Resistance Training and Fish Protein Intake on Motor Unit Firing Pattern and Motor Function of Elderly. / 2018 / PubMed / Full text
The amyloid precursor protein (APP) processing as a biological link between Alzheimer's disease and cancer. / 01.2019 / PubMed / Full text
Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study. / 06.11.2018 / PubMed / Full text
Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex. / 06.2019 / PubMed / Full text
Increased Insoluble Amyloid-β Induces Negligible Cognitive Deficits in Old AppNL/NL Knock-In Mice. / 2018 / PubMed / Full text
Long-term dietary supplementation with the green tea cultivar Sunrouge prevents age-related cognitive decline in the senescence-accelerated mouse Prone8. / 02.2019 / PubMed / Full text
Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice. / 19.09.2018 / PubMed / Full text
The age of peak performance in women and men duathletes - The paradigm of short and long versions in "Powerman Zofingen". / 2018 / PubMed / Full text
Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice. / 10.2018 / PubMed / Full text
Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
Alterations of functional circuitry in aging brain and the impact of mutated APP expression. / 10.2018 / PubMed / Full text
Menadione sodium bisulfite inhibits the toxic aggregation of amyloid-β(1-42). / 10.2018 / PubMed / Full text
Sirtuin 1 and Alzheimer's disease: An up-to-date review. / 10.2018 / PubMed / Full text
Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease. / 10.2018 / PubMed / Full text
Human Cord Blood Serum-Derived APP α-Secretase Cleavage Activity is Mediated by C1 Complement. / 04.2018 / PubMed / Full text
Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport. / 08.2018 / PubMed / Full text
Blood-Brain Barrier Disruption and Perivascular Beta-Amyloid Accumulation in the Brain of Aged Rats with Spontaneous Hypertension: Evaluation with Dynamic Contrast-Enhanced Magnetic Resonance Imaging. / 05-06.2018 / PubMed / Full text
Drosophila Full-Length Amyloid Precursor Protein Is Required for Visual Working Memory and Prevents Age-Related Memory Impairment. / 05.03.2018 / PubMed / Full text
β-amyloid expression in age-related cataract lens epithelia and the effect of β-amyloid on oxidative damage in human lens epithelial cells. / 2017 / PubMed / Full text
Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells. / 15.01.2018 / PubMed / Full text
Disturbances in the control of capillary flow in an aged APP /PS1ΔE9 model of Alzheimer's disease. / 02.2018 / PubMed / Full text
Istradefylline reduces memory deficits in aging mice with amyloid pathology. / 02.2018 / PubMed / Full text
The age-related slow increase in amyloid pathology in APP.V717I mice activates microglia, but does not alter hippocampal neurogenesis. / 01.2018 / PubMed / Full text
Sortilin inhibits amyloid pathology by regulating non-specific degradation of APP. / 01.2018 / PubMed / Full text
Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease. / 12.2017 / PubMed / Full text
Analyzing Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation in Aging and Vascular Amyloid Pathology. / 2017 / PubMed / Full text

CAT

Training improves the handling of inhaler devices and reduces the severity of symptoms in geriatric patients suffering from chronic-obstructive pulmonary disease. / 09.10.2020 / PubMed / Full text
7-chloro-4-(phenylselanyl) quinoline co-treatment prevent oxidative stress in diabetic-like phenotype induced by hyperglycidic diet in Drosophila melanogaster. / 01.2021 / PubMed / Full text
Aging influences in the blood-brain barrier permeability and cerebral oxidative stress in sepsis. / 15.10.2020 / PubMed / Full text
2 -Deoxy - d-glucose at chronic low dose acts as a caloric restriction mimetic through a mitohormetic induction of ROS in the brain of accelerated senescence model of rat. / 09-10.2020 / PubMed / Full text
Ceftriaxone improves senile neurocognition damages induced by D-galactose in mice. / 03.2020 / PubMed / Full text
Ginsenoside Rg1 protects against d-galactose induced fatty liver disease in a mouse model via FOXO1 transcriptional factor. / 01.08.2020 / PubMed / Full text
Effects of long-term intermittent versus chronic calorie restriction on oxidative stress in a mouse cancer model. / 12.2019 / PubMed / Full text
The Toxicity of Nonaged and Aged Coated Silver Nanoparticles to Freshwater Alga Raphidocelis subcapitata. / 11.2019 / PubMed / Full text
Function, Oxidative, and Inflammatory Stress Parameters in Immune Cells as Predictive Markers of Lifespan throughout Aging. / 2019 / PubMed / Full text
Potential effects of rapeseed peptide Maillard reaction products on aging-related disorder attenuation and gut microbiota modulation in d-galactose induced aging mice. / 17.07.2019 / PubMed / Full text
Forkhead box O3 protects the heart against paraquat-induced aging-associated phenotypes by upregulating the expression of antioxidant enzymes. / 10.2019 / PubMed / Full text
Structure Characterization and Action Mechanism of an Antiaging New Compound from [i]Gastrodia elata[/i] Blume. / 2019 / PubMed / Full text
Subcellular targets of zinc oxide nanoparticles during the aging process: role of cross-talk between mitochondrial dysfunction and endoplasmic reticulum stress in the genotoxic response. / 07.06.2019 / PubMed / Full text
Exercise training initiated at old stage of lifespan attenuates aging-and ovariectomy-induced cardiac and renal oxidative stress: Role of baroreflex. / 09.2019 / PubMed / Full text
Changes in the blood antioxidant defense of advanced age people. / 2019 / PubMed / Full text
Preventive effect of Lactobacillus plantarum KSFY02 isolated from naturally fermented yogurt from Xinjiang, China, on d-galactose-induced oxidative aging in mice. / 07.2019 / PubMed / Full text
Health status deterioration in subjects with mild to moderate airflow obstruction, a six years observational study. / 18.05.2019 / PubMed / Full text
Effect of Coenzyme Q10 Alone and in Combination with Exercise Training on Oxidative Stress Biomarkers in Rats. / 06.2018 / PubMed / Full text
Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway. / 07.2019 / PubMed / Full text
Link between cardiac function and the antioxidative defense mechanism in aged rats. / 11.06.2019 / PubMed / Full text
Relation of Redox and Structural Alterations of Rat Skin in the Function of Chronological Aging. / 2019 / PubMed / Full text
Administration of rGDF11 retards the aging process in male mice via action of anti-oxidant system. / 08.2019 / PubMed / Full text
Relation between cognitive and cerebello-thalamo-cortical functions in healthy elderly people: Evidence from the Yakumo Study. / 07-08.2020 / PubMed / Full text
Ameliorative effect of supercritical fluid extract of Chrysanthemum indicum Linnén against D-galactose induced brain and liver injury in senescent mice via suppression of oxidative stress, inflammation and apoptosis. / 24.04.2019 / PubMed / Full text
Curcumin supplementation increases survival and lifespan in Drosophila under heat stress conditions. / 11.2018 / PubMed / Full text
Glycolytic Inhibitor 2-Deoxy-D-Glucose at Chronic Low Dose Mimics Calorie Restriction in Rats Through Mitohormetic Induction of Reactive Oxygen Species. / 10.2019 / PubMed / Full text
[i]Lactobacillus plantarum[/i] CQPC11 Isolated from Sichuan Pickled Cabbages Antagonizes d-galactose-Induced Oxidation and Aging in Mice. / 20.11.2018 / PubMed / Full text
Effect of dietary L-tryptophan on the survival, immune response and gut microbiota of the Chinese mitten crab, Eriocheir sinensis. / 01.2019 / PubMed / Full text
Astaxanthin-Rich [i]Haematococcus pluvialis[/i] Algal Hepatic Modulation in D-Galactose-Induced Aging in Rats: Role of Nrf2. / 08.2018 / PubMed / Full text
Age-dependent survival, stress defense, and AMPK in Daphnia pulex after short-term exposure to a polystyrene nanoplastic. / 11.2018 / PubMed / Full text
Age- and sex-dependent variation in the activity of antioxidant enzymes in the brown trout (Salmo trutta). / 02.2019 / PubMed / Full text
The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity. / 2018 / PubMed / Full text
[Effects of the [i]Fomes officinalis[/i] flavonoids on anti-senile action in the aging model mice]. / 08.02.2016 / PubMed / Full text
The influence of ageing on the extrapineal melatonin synthetic pathway. / 09.2018 / PubMed / Full text
Comparing Palm Oil, Tocotrienol-Rich Fraction and α-Tocopherol Supplementation on the Antioxidant Levels of Older Adults. / 28.05.2018 / PubMed / Full text
Resveratrol improves in vitro maturation of oocytes in aged mice and humans. / 05.2018 / PubMed / Full text
Effect of β-D-Mannuronic Acid (M2000) on Oxidative Stress Enzymes' Gene Using Healthy Donor Peripheral Blood Mononuclear Cells for Evaluating the Anti-Aging Property. / 2019 / PubMed / Full text
[Effects of water conditions and controlled release urea on yield and leaf senescence physiological characteristics in summer maize.] / 02.2017 / PubMed / Full text
Mechanisms of the active components from Korean pine nut preventing and treating d-galactose-induced aging rats. / 07.2018 / PubMed / Full text
Effects of a probiotic (Bacillus licheniformis) on the growth, immunity, and disease resistance of Haliotis discus hannai Ino. / 05.2018 / PubMed / Full text
Recombinant buckwheat glutaredoxin intake increases lifespan and stress resistance via hsf-1 upregulation in Caenorhabditis elegans. / 04.2018 / PubMed / Full text
Sargassum fusiforme Polysaccharide Rejuvenat es the Small Intestine in Mice Through Altering its Physiol ogy and Gut Microbiota Composition. / 2017 / PubMed / Full text
Piceatannol attenuates behavioral disorder and neurological deficits in aging mice via activating the Nrf2 pathway. / 24.01.2018 / PubMed / Full text
Phase angle is related with inflammatory and oxidative stress biomarkers in older women. / 02.2018 / PubMed / Full text
Effect of selenium on testicular damage induced by varicocele in adult male Wistar rats. / 12.2017 / PubMed / Full text
Aqueous root extract of Asparagus cochinchinensis (Lour.) Merr. Has antioxidant activity in D-galactose-induced aging mice. / 25.09.2017 / PubMed / Full text
The antioxidative and anti-aging effects of acidic- and alkalic-extractable mycelium polysaccharides by Agrocybe aegerita (Brig.) Sing. / 01.2018 / PubMed / Full text

CD28

Premature CD4 T Cells Senescence Induced by Chronic Infection in Patients with Acute Coronary Syndrome. / 12.2020 / PubMed / Full text
The IMMENSE Study: The Interplay Between iMMune and ENdothelial Cells in Mediating Cardiovascular Risk in Systemic Lupus Erythematosus. / 2020 / PubMed / Full text
Emergence of T cell immunosenescence in diabetic chronic kidney disease. / 2020 / PubMed / Full text
The relationship between Chlamydia pneumoniae infection and CD4/CD8 ratio, lymphocyte subsets in middle-aged and elderly individuals. / 12.2020 / PubMed / Full text
Next steps in mechanisms of inflammaging. / 22.09.2020 / PubMed / Full text
A randomized pilot trial to evaluate the benefit of the concomitant use of atorvastatin and Raltegravir on immunological markers in protease-inhibitor-treated subjects living with HIV. / 2020 / PubMed / Full text
Aging affects responsiveness of peripheral blood mononuclear cells to immunosuppression of periodontal ligament stem cells. / 07.2020 / PubMed / Full text
Comparison of Donepezil, Memantine, Melatonin, and Liuwei Dihuang Decoction on Behavioral and Immune Endocrine Responses of Aged Senescence-Accelerated Mouse Resistant 1 Mice. / 2020 / PubMed / Full text
Immunosenescent characteristics of T cells in young patients following haploidentical haematopoietic stem cell transplantation from parental donors. / 04.2020 / PubMed / Full text
Diagnosis-independent loss of T-cell costimulatory molecules in individuals with cytomegalovirus infection. / 07.2020 / PubMed / Full text
Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression. / 2020 / PubMed / Full text
Accelerated immune aging was correlated with lupus-associated brain fog in reproductive-age systemic lupus erythematosus patients. / 05.2020 / PubMed / Full text
T cells, aging and senescence. / 22.02.2020 / PubMed / Full text
Liver fibrosis and accelerated immune dysfunction (immunosenescence) among HIV-infected Russians with heavy alcohol consumption - an observational cross-sectional study. / 31.12.2019 / PubMed / Full text
Effect of Allogenic Bone Marrow Mesenchymal Stem Cell Transplantation on T Cells of Old Mice. / 02.2020 / PubMed / Full text
Peripheral antibody concentrations are associated with highly differentiated T cells and inflammatory processes in the human bone marrow. / 2019 / PubMed / Full text
Collaboration of MYC and RUNX2 in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity. / 10.2019 / PubMed / Full text
The Evolving Role of CD8 CD28 Immunosenescent T Cells in Cancer Immunology. / 08.06.2019 / PubMed / Full text
Are skin senescence and immunosenescence linked within individuals? / 08.2019 / PubMed / Full text
Expanded peripheral CD4 CD28 T cells and its association with atherosclerotic changes in patients with end stage renal disease on hemodialysis. / 09.2019 / PubMed / Full text
Impact of aging on inflammatory and immune responses during elastin peptide-induced murine emphysema. / 01.04.2019 / PubMed / Full text
Low DNA damage in peripheral lymphocytes of healthy elderly individuals with inverted CD4:CD8 ratio. / 02.2019 / PubMed / Full text
Post-thymic CD4 positive cytotoxic T cell infiltrates of the skin: A clinical and histomorphologic spectrum of the unique CD4 positive T cell of immunosenescence. / 02.2019 / PubMed / Full text
Immune Response-Dependent Assembly of IMP Dehydrogenase Filaments. / 2018 / PubMed / Full text
Reduced expression of the lncRNA NRON is a potential hallmark of the CMV-amplified CD8+ T cell accumulations commonly seen in older humans. / 01.2019 / PubMed / Full text
Low IL-2 Expressing T Cells in Thalassemia Major Patients: Is It Immune Aging. / 10.2018 / PubMed / Full text
CD28 pro-atherogenic CD4 T-cells explain the link between CMV infection and an increased risk of cardiovascular death. / 2018 / PubMed / Full text
Senescence markers: Predictive for response to checkpoint inhibitors. / 01.03.2019 / PubMed / Full text
An imbalance in the T-helper phenotypes displayed by senescent CD4 CD28 T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus. / 11.2018 / PubMed / Full text
Features of Immunosenescence in Women Newly Diagnosed With Breast Cancer. / 2018 / PubMed / Full text
Innate and adaptive immune dysregulation in critically ill ICU patients. / 05.07.2018 / PubMed / Full text
Is Chronic Exposure to Low-Dose Organochlorine Pesticides a New Risk Factor of T-cell Immunosenescence? / 10.2018 / PubMed / Full text
Involvement of MicroRNAs in the Aging-Related Decline of CD28 Expression by Human T Cells. / 2018 / PubMed / Full text
Older men display elevated levels of senescence-associated exercise-responsive CD28 angiogenic T cells compared with younger men. / 06.2018 / PubMed / Full text
Multi-color flow cytometry for evaluating age-related changes in memory lymphocyte subsets in dogs. / 10.2018 / PubMed / Full text
Abnormalities of age-related T cell senescence in Parkinson's disease. / 28.05.2018 / PubMed / Full text
CD57 identifies T cells with functional senescence before terminal differentiation and relative telomere shortening in patients with activated PI3 kinase delta syndrome. / 11.2018 / PubMed / Full text
Low cytomegalovirus seroprevalence in early multiple sclerosis: a case for the 'hygiene hypothesis'? / 07.2018 / PubMed / Full text
Senescent T-Cells Promote Bone Loss in Rheumatoid Arthritis. / 2018 / PubMed / Full text
T-cell Immunoglobulin and ITIM Domain Contributes to CD8 T-cell Immunosenescence. / 04.2018 / PubMed / Full text
Signal transduction changes in CD4 and CD8 T cell subpopulations with aging. / 05.2018 / PubMed / Full text
Increased senescent CD8+ T cells in the peripheral blood mononuclear cells of Behçet's disease patients. / 03.2018 / PubMed / Full text
Immune parameters associated with mortality in the elderly are context-dependent: lessons from Sweden, Holland and Belgium. / 12.2018 / PubMed / Full text
T-cell differentiation and CD56+ levels in polypoidal choroidal vasculopathy and neovascular age-related macular degeneration. / 20.11.2017 / PubMed / Full text
[Effects of serums containing Buzhong Yiqi decoction with Astragalus Radix or Hedysari Radix on anti-immunosenescence in spleen lymphocytes of SAMP8 mice]. / 08.2016 / PubMed / Full text
Arterial Stiffness Is Associated With Cytomegalovirus-Specific Senescent CD8 T Cells. / 28.08.2017 / PubMed / Full text

SCD

Cognitive training and brain stimulation in prodromal Alzheimer's disease (AD-Stim)-study protocol for a double-blind randomized controlled phase IIb (monocenter) trial. / 07.11.2020 / PubMed / Full text
Blood Pressure in Different Dementia Disorders, Mild Cognitive Impairment, and Subjective Cognitive Decline. / 2020 / PubMed / Full text
Known-Groups and Convergent Validity of the Telephone Rey Auditory Verbal Learning Test total Learning Scores for Distinguishing Between Older Adults With Amnestic Cognitive Impairment and Subjective Cognitive Decline. / 17.10.2020 / PubMed / Full text
Subjective cognitive decline as a predictor of future cognitive decline: a systematic review. / 07-09.2020 / PubMed / Full text
Geriatric assessment for older adults with sickle cell disease: protocol for a prospective cohort pilot study. / 2020 / PubMed / Full text
Prevalence and psychosocial correlates of subjectively perceived decline in five cognitive domains: Results from a population-based cohort study in Germany. / 08.06.2020 / PubMed / Full text
SC411 treatment can enhance survival in a mouse model of sickle cell disease. / 07.2020 / PubMed / Full text
DNA fragmentation of human spermatozoa: Simple assessment of single- and double-strand DNA breaks and their respective dynamic behavioral response. / 09.2020 / PubMed / Full text
Psychometric Cognitive Decline Precedes the Advent of Subjective Cognitive Decline in the Evolution of Alzheimer's Disease. / 2020 / PubMed / Full text
Serum alkaline phosphatase is elevated and inversely correlated with cognitive functions in subjective cognitive decline: results from the ReGAl 2.0 project. / 03.05.2020 / PubMed / Full text
Changes in Activity Participation Among Older Adults With Subjective Cognitive Decline or Objective Cognitive Deficits. / 2019 / PubMed / Full text
Age, gender and drug therapy influences on Tpeak-tend interval and on electrical risk score. / 03-04.2020 / PubMed / Full text
Comorbid Chronic Conditions Among Older Adults with Subjective Cognitive Decline, United States, 2015-2017. / 2020 / PubMed / Full text
Resting State BOLD Variability Is Linked to White Matter Vascular Burden in Healthy Aging but Not in Older Adults With Subjective Cognitive Decline. / 2019 / PubMed / Full text
Estimated Life Expectancy and Income of Patients With Sickle Cell Disease Compared With Those Without Sickle Cell Disease. / 01.11.2019 / PubMed / Full text
Does Empirically Derived Classification of Individuals with Subjective Cognitive Complaints Predict Dementia? / 07.11.2019 / PubMed / Full text
Spatiotemporal Oscillatory Patterns During Working Memory Maintenance in Mild Cognitive Impairment and Subjective Cognitive Decline. / 01.2020 / PubMed / Full text
Microstructural Correlates and Laterality Effect of Prospective Memory in Non-Demented Adults with Memory Complaints. / 2019 / PubMed / Full text
Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis. / 2019 / PubMed / Full text
Multisensory, Multi-Tasking Performance of Older Adults With and Without Subjective Cognitive Decline. / 01.01.2019 / PubMed / Full text
Diffusion tensor imaging reveals abnormal brain networks in elderly subjects with subjective cognitive deficits. / 11.2019 / PubMed / Full text
Visual impairment in aging and cognitive decline: experience in a Memory Clinic. / 18.06.2019 / PubMed / Full text
Differences in Subjective Cognitive Complaints Between Non-Demented Older Adults from a Memory Clinic and the Community. / 2019 / PubMed / Full text
Frailty Is Related to Subjective Cognitive Decline in Older Women without Dementia. / 09.2019 / PubMed / Full text
Cognitive Function in Sickle Cell Disease Across Domains, Cerebral Infarct Status, and the Lifespan: A Meta-Analysis. / 01.09.2019 / PubMed / Full text
Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)-study protocol for a randomized controlled trial. / 01.05.2019 / PubMed / Full text
Subjective Cognitive Decline in the Community Is Affected at Multiple Aspects of Mental Health and Life Quality: A Cross-Sectional Study of the Community Medicine of Keelung Chang Gung Memorial Hospital. / 01-04.2019 / PubMed / Full text
Symptom clusters of subjective cognitive decline amongst cognitively normal older persons and their utilities in predicting objective cognitive performance: structural equation modelling. / 09.2019 / PubMed / Full text
State inequality, socioeconomic position and subjective cognitive decline in the United States. / 04.2019 / PubMed / Full text
Myocardial lipofuscin accumulation in ageing and sudden cardiac death. / 01.03.2019 / PubMed / Full text
Discriminating Alzheimer's disease progression using a new hippocampal marker from T1-weighted MRI: The local surface roughness. / 01.04.2019 / PubMed / Full text
Bone marrow neutrophil aging in sickle cell disease mice is associated with impaired osteoblast functions. / 12.2018 / PubMed / Full text
Subjective Cognitive Decline Prediction of Mortality: Results from the Einstein Aging Study. / 2018 / PubMed / Full text
Internal Consistency Over Time of Subjective Cognitive Decline: Drawing Preclinical Alzheimer's Disease Trajectories. / 2018 / PubMed / Full text
Callosal circularity as an early marker for Alzheimer's disease. / 2018 / PubMed / Full text
Subjective cognitive decline and risk of MCI: The Mayo Clinic Study of Aging. / 24.07.2018 / PubMed / Full text
Correlates of Subjective Cognitive Decline in Lesbian, Gay, Bisexual, and Transgender Older Adults. / 2018 / PubMed / Full text
Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice. / 29.05.2018 / PubMed / Full text
Sickle Cell Clinical Research and Intervention Program (SCCRIP): A lifespan cohort study for sickle cell disease progression from the pediatric stage into adulthood. / 09.2018 / PubMed / Full text
Subjective Cognitive Decline, Objective Cognition, and Depression in Older Hispanics Screened for Memory Impairment. / 2018 / PubMed / Full text
Comorbidities in aging patients with sickle cell disease. / 2018 / PubMed / Full text
Screening for cognitive impairment in an Australian aged care assessment team as part of comprehensive geriatric assessment. / 05.2019 / PubMed / Full text
Executive and Language Subjective Cognitive Decline Complaints Discriminate Preclinical Alzheimer's Disease from Normal Aging. / 2018 / PubMed / Full text
Identification of cytochrome b5 CYTB-5.1 and CYTB-5.2 in C. elegans; evidence for differential regulation of SCD. / 03.2018 / PubMed / Full text
Subjective Cognitive Decline Modifies the Relationship Between Cerebral Blood Flow and Memory Function in Cognitively Normal Older Adults. / 03.2018 / PubMed / Full text
Subjective cognitive decline and β-amyloid burden predict cognitive change in healthy elderly. / 07.11.2017 / PubMed / Full text

NLRP3

Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience. / 12.2020 / PubMed / Full text
TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity. / 27.10.2020 / PubMed / Full text
Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and NLRP3 inflammasome. / 01.01.2021 / PubMed / Full text
A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma. / 13.10.2020 / PubMed / Full text
Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress. / 2020 / PubMed / Full text
Mechanisms of NLRP3 priming in inflammaging and age related diseases. / 10.2020 / PubMed / Full text
Lamivudine Inhibits [i]Alu[/i] RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities. / 07.2020 / PubMed / Full text
The NLRP3 Inflammasome: Metabolic Regulation and Contribution to Inflammaging. / 30.07.2020 / PubMed / Full text
Aging aggravated liver ischemia and reperfusion injury by promoting STING-mediated NLRP3 activation in macrophages. / 08.2020 / PubMed / Full text
Targeting NLRP3 Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss. / 10.2020 / PubMed / Full text
Korean Red Ginseng Suppresses the Expression of Oxidative Stress Response and NLRP3 Inflammasome Genes in Aged C57BL/6 Mouse Ovaries. / 22.04.2020 / PubMed / Full text
Cepharanthine promotes the effect of dexmedetomidine on the deposition of β-amyloid in the old age of the senile dementia rat model by regulating inflammasome expression. / 2019 / PubMed / Full text
Ginsenoside Rg1 ameliorates glomerular fibrosis during kidney aging by inhibiting NOX4 and NLRP3 inflammasome activation in SAMP8 mice. / 27.02.2020 / PubMed / Full text
Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice. / 04.2020 / PubMed / Full text
Autophagy and NLRP3 inflammasome crosstalk in neuroinflammation in aged bovine brains. / 06.2020 / PubMed / Full text
NLRP3 Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity. / 13.07.2020 / PubMed / Full text
NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice. / 01.2020 / PubMed / Full text
Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging. / 08.09.2019 / PubMed / Full text
Effect of Aging on Taurine Transporter (TauT) Expression in the Mouse Brain Cortex. / 2019 / PubMed / Full text
Tamoxifen-induced, intestinal-specific deletion of [i]Slc5a6[/i] in adult mice leads to spontaneous inflammation: involvement of NF-κB, NLRP3, and gut microbiota. / 01.10.2019 / PubMed / Full text
Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome. / 02.09.2019 / PubMed / Full text
Aging in the Syrian hamster testis: Inflammatory-oxidative status and the impact of photoperiod. / 09.2019 / PubMed / Full text
[Improved effects of saponins from Panax japonicus on decline of cognitive function in natural aging rats via NLRP3 inflammasome pathway]. / 01.2019 / PubMed / Full text
Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin. / 04.10.2019 / PubMed / Full text
Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks. / 11.03.2019 / PubMed / Full text
NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats. / 04.2019 / PubMed / Full text
Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. / 22.01.2019 / PubMed / Full text
Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence. / 05.2019 / PubMed / Full text
Inhibiting the NLRP3 Inflammasome With MCC950 Ameliorates Isoflurane-Induced Pyroptosis and Cognitive Impairment in Aged Mice. / 2018 / PubMed / Full text
Klotho controls the brain-immune system interface in the choroid plexus. / 27.11.2018 / PubMed / Full text
NLRP3 inflammasome activation in inflammaging. / 12.2018 / PubMed / Full text
Melatonin and inflammation-Story of a double-edged blade. / 11.2018 / PubMed / Full text
A response to readers' comments. / 14.09.2018 / PubMed / Full text
NLRP3 inflammasome-dependent pyroptosis is proposed to be involved in the mechanism of age-dependent isoflurane-induced cognitive impairment. / 14.09.2018 / PubMed / Full text
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. / 09.2018 / PubMed / Full text
Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain. / 06.2018 / PubMed / Full text
Critical role of NLRP3-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment. / 17.04.2018 / PubMed / Full text
Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection. / 05.2018 / PubMed / Full text
AMP-Activated Protein Kinase Regulation of the NLRP3 Inflammasome during Aging. / 01.2018 / PubMed / Full text
Effects of chronically increased VEGF-A on the aging heart. / 03.2018 / PubMed / Full text
NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection. / 01.03.2018 / PubMed / Full text
Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. / 05.10.2017 / PubMed / Full text
Specific calpain inhibition protects kidney against inflammaging. / 14.08.2017 / PubMed / Full text

ACE

Elite swimmers possess shorter telomeres than recreationally active controls. / 15.10.2020 / PubMed / Full text
Coronavirus Disease-2019 Conundrum: RAS Blockade and Geriatric-Associated Neuropsychiatric Disorders. / 2020 / PubMed / Full text
Pregnancy Protects Hyperandrogenemic Female Rats From Postmenopausal Hypertension. / 09.2020 / PubMed / Full text
Heart failure is associated with accelerated age related metabolic bone disease. / 05.06.2020 / PubMed / Full text
Management of heart failure: an Italian national survey on fellows/specialists in geriatrics. / 10.2020 / PubMed / Full text
Angiotensin-Converting Enzyme (ACE) genetic variation and longevity in Peruvian older people: a cross-sectional study. / 05.2020 / PubMed / Full text
COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection? / 30.03.2020 / PubMed / Full text
[i]A[/i]ngiotensin Converting Enzyme Inhibitors [i]C[/i]ombined with [i]E[/i]xercise for Hypertensive [i]S[/i]eniors (The ACES Trial): Study Protocol of a Randomized Controlled Trial. / 2019 / PubMed / Full text
Vascular age. / Winter.2020 / PubMed
Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
The renin-angiotensin aldosterone system and osteoporosis: findings from the Women's Health Initiative. / 10.2019 / PubMed / Full text
Adverse Childhood Experiences and Telomere Length a Look Into the Heterogeneity of Findings-A Narrative Review. / 2019 / PubMed / Full text
Obesity and aging affects skeletal muscle renin-angiotensin system and myosin heavy chain proportions in pre-diabetic Zucker rats. / 08.2019 / PubMed / Full text
Lisinopril Preserves Physical Resilience and Extends Life Span in a Genotype-Specific Manner in Drosophila melanogaster. / 13.11.2019 / PubMed / Full text
Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study. / 14.05.2019 / PubMed / Full text
Identifying the lifetime cognitive and socioeconomic antecedents of cognitive state: seven decades of follow-up in a British birth cohort study. / 24.04.2019 / PubMed / Full text
Association between Adverse Childhood Experiences and Muscle Strength in Older Age. / 2019 / PubMed / Full text
Feasibility Trial Evaluation of a Peer Volunteering Active Aging Intervention: ACE (Active, Connected, Engaged). / 02.04.2020 / PubMed / Full text
Deletion Polymorphism of Angiotensin-Converting Enzyme Gene Is Associated with Low Muscle Mass in Elderly People in Jakarta, Indonesia. / 12.11.2018 / PubMed / Full text
The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature. / 01.08.2019 / PubMed / Full text
Newly manufactured Marukome MK-34-1 miso with angiotensin-converting enzyme inhibitory activity and its antihypertensive effects in genetic hypertensive rat models. / 06.2019 / PubMed / Full text
Impact of resilience on health in older adults: a cross-sectional analysis from the International Mobility in Aging Study (IMIAS). / 28.11.2018 / PubMed / Full text
Age-related impairment in Addenbrooke's cognitive examination revised scores in patients with amyotrophic lateral sclerosis. / 11.2018 / PubMed / Full text
The Edinburgh Cognitive and Behavioral ALS screen: relationship to age, education, IQ and the Addenbrooke's Cognitive Examination-III. / 11.2018 / PubMed / Full text
Age- and Genotype-Specific Effects of the Angiotensin-Converting Enzyme Inhibitor Lisinopril on Mitochondrial and Metabolic Parameters in [i]Drosophila melanogaster[/i]. / 26.10.2018 / PubMed / Full text
Relevance of TSH evaluation in elderly in-patients with non-thyroidal illness. / 06.2019 / PubMed / Full text
Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study. / 2018 / PubMed / Full text
The Use of Mobile Games to Assess Cognitive Function of Elderly with and without Cognitive Impairment. / 2018 / PubMed / Full text
Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. / 10.2018 / PubMed / Full text
Onset Time of Inhibition of Return Is a Promising Index for Assessing Cognitive Functions in Older Adults. / 09.03.2020 / PubMed / Full text
Improving the comprehension of sarcopenic state determinants: An multivariate approach involving hormonal, nutritional, lifestyle and genetic variables. / 07.2018 / PubMed / Full text
Neuroticism predicts all-cause mortality over 19-years: The moderating effects on functional status, and the angiotensin-converting enzyme. / 07.2018 / PubMed / Full text
Adverse Childhood Experiences among a Community of Resilient Centenarians and Seniors: Implications for a Chronic Disease Prevention Framework. / 2018 / PubMed / Full text
Adverse Childhood Experiences and Young Adult Health Outcomes Among Youth Aging Out of Foster Care. / 07.2018 / PubMed / Full text
Sex differences in transcriptomic profiles in aged kidney cells of renin lineage. / 18.04.2018 / PubMed / Full text
The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system. / 03.2018 / PubMed / Full text
Comorbidity scores associated with limited life expectancy in the very elderly with nonmelanoma skin cancer. / 06.2018 / PubMed / Full text
Changes in prescription patterns in older hospitalized patients: the impact of FORTA on disease-related over- and under-treatments. / 03.2018 / PubMed / Full text
Relationship of quadriceps muscle power and optimal shortening velocity with angiotensin-converting enzyme activity in older women. / 2017 / PubMed / Full text
Effects of different antihypertensive medication groups on cognitive function in older patients: A systematic review. / 10.2017 / PubMed / Full text
The Test Your Memory for Mild Cognitive Impairment (TYM-MCI). / 12.2017 / PubMed / Full text
Life Course Pathways From Adverse Childhood Experiences to Adult Physical Health: A Structural Equation Model. / 02.2019 / PubMed / Full text

AMH

Beyond premature ovarian insufficiency: Staging reproductive aging in adolescent and young adult cancer survivors. / 03.11.2020 / PubMed / Full text
Correlates and Timing of Reproductive Aging Transitions in a Global Cohort of Midlife Women With Human Immunodeficiency Virus: Insights From the REPRIEVE Trial. / 09.07.2020 / PubMed / Full text
Epigenetic clock measuring age acceleration via DNA methylation levels in blood is associated with decreased oocyte yield. / 05.2020 / PubMed / Full text
Modeling Variation in the Reproductive Lifespan of Female Adolescent and Young Adult Cancer Survivors Using AMH. / 01.08.2020 / PubMed / Full text
Improving Prediction of Age at Menopause Using Multiple Anti-Müllerian Hormone Measurements: the Tehran Lipid-Glucose Study. / 01.05.2020 / PubMed / Full text
Antimullerian Hormone and Impending Menopause in Late Reproductive Age: The Study of Women's Health Across the Nation. / 01.04.2020 / PubMed / Full text
Basal characterization and in vitro differentiation of putative stem cells derived from the adult mouse ovary. / 01.2020 / PubMed / Full text
Serum anti-Müllerian hormone concentration and follicle density throughout reproductive life and in different diseases-implications in fertility preservation. / 01.12.2019 / PubMed / Full text
Associations Between Anti-Mullerian Hormone and Cardiometabolic Health in Reproductive Age Women Are Explained by Body Mass Index. / 01.01.2020 / PubMed / Full text
Relationships between antral follicle count, blood serum concentration of anti-Müllerian hormone and fertility in mares. / 10.2019 / PubMed / Full text
Amyloid-like substance in mice and human oocytes and embryos. / 09.2019 / PubMed / Full text
Is in utero exposure to maternal socioeconomic disadvantage related to offspring ovarian reserve in adulthood? / 2018 / PubMed / Full text
Physiology and endocrinology symposium: Anti-Müllerian hormone: a biomarker for the ovarian reserve, ovarian function, and fertility in dairy cows. / 03.04.2019 / PubMed / Full text
Genome-wide association study of anti-Müllerian hormone levels in pre-menopausal women of late reproductive age and relationship with genetic determinants of reproductive lifespan. / 15.04.2019 / PubMed / Full text
Low MFN2 expression related to ageing in granulosa cells is associated with assisted reproductive technology outcome. / 02.2019 / PubMed / Full text
Differential Rates of Change in Measures of Ovarian Reserve in Young Cancer Survivors Across the Reproductive Lifespan. / 01.05.2019 / PubMed / Full text
Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation. / 2018 / PubMed / Full text
Relationship between anti-Müllerian hormone and fertility in the mare. / 02.2019 / PubMed / Full text
Effect of intra-ovarian injection of mesenchymal stem cells in aged mares. / 03.2019 / PubMed / Full text
Possibilities and real meaning of assessment of ovarian reserve. / 2018.Fall / PubMed
Effects of icariin on ovarian function in d-galactose-induced aging mice. / 02.2019 / PubMed / Full text
Anti-Müllerian hormone and ovarian aging in mares. / 01.02.2019 / PubMed / Full text
Age-related nomograms of serum anti-Mullerian hormone levels in female monkeys: Comparison of rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) monkeys. / 01.12.2018 / PubMed / Full text
The relationship between anti-Müllerian hormone serum level and body mass index in a large cohort of infertile patients. / 01.2019 / PubMed / Full text
Antral follicular count is a tool that may allow the selection of more precocious Bradford heifers at weaning. / 01.10.2018 / PubMed / Full text
Chronological age vs biological age: a retrospective analysis on age-specific serum anti-Müllerian hormone levels for 3280 females in reproductive center clinic. / 10.2018 / PubMed / Full text
Premature ovarian aging in [i]BRCA[/i] carriers: a prototype of systemic precocious aging? / 23.03.2018 / PubMed / Full text
With low ovarian reserve, Highly Individualized Egg Retrieval (HIER) improves IVF results by avoiding premature luteinization. / 16.03.2018 / PubMed / Full text
Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor. / 09.03.2018 / PubMed / Full text
First data on in vitro fertilization and blastocyst formation after intraovarian injection of calcium gluconate-activated autologous platelet rich plasma. / 09.2018 / PubMed / Full text
Differential rate in decline in ovarian reserve markers in women with polycystic ovary syndrome compared with control subjects: results of a longitudinal study. / 03.2018 / PubMed / Full text
Suspected ontogeny of a recently described hypo-androgenic PCOS-like phenotype with advancing age. / 03.2018 / PubMed / Full text
Ovarian aging is associated with gray matter volume and disability in women with MS. / 16.01.2018 / PubMed / Full text
The Impact of a Long-Acting Oral Sphingosine-1-Phosphate Analogue on Ovarian Aging in a Rat Model. / 09.2018 / PubMed / Full text
Prediction of age at menopause in women with polycystic ovary syndrome. / 02.2018 / PubMed / Full text
Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. / 18.10.2017 / PubMed / Full text
Effect of age and castration on serum anti-Müllerian hormone concentration in male alpacas. / 01.01.2018 / PubMed / Full text
Establishing age-specific reference intervals for anti-Müllerian hormone in adult Chinese women based on a multicenter population. / 11.2017 / PubMed / Full text
Plasma anti-Müllerian hormone profile in heifers from birth through puberty and relationship with puberty onset. / 01.07.2017 / PubMed / Full text
Age-related decline in AMH is assay dependent limiting clinical interpretation of repeat AMH measures across the reproductive lifespan. / 02.2018 / PubMed / Full text

AR

Mechanisms of Androgen Receptor Agonist- and Antagonist-Mediated Cellular Senescence in Prostate Cancer. / 08.07.2020 / PubMed / Full text
Interleukin-23 Represses the Level of Cell Senescence Induced by the Androgen Receptor Antagonists Enzalutamide and Darolutamide in Castration-Resistant Prostate Cancer Cells. / 08.2020 / PubMed / Full text
A Landscape of Murine Long Non-Coding RNAs Reveals the Leading Transcriptome Alterations in Adipose Tissue during Aging. / 26.05.2020 / PubMed / Full text
Senolytic compounds control a distinct fate of androgen receptor agonist- and antagonist-induced cellular senescent LNCaP prostate cancer cells. / 2020 / PubMed / Full text
Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice. / 01.04.2020 / PubMed / Full text
A jaboticaba extract prevents prostatic damage associated with aging and high-fat diet intake. / 26.02.2020 / PubMed / Full text
Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip. / 10.2019 / PubMed / Full text
Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging. / 05.09.2019 / PubMed / Full text
Androgen receptor signalling in the male adrenal facilitates X-zone regression, cell turnover and protects against adrenal degeneration during ageing. / 18.07.2019 / PubMed / Full text
Enhanced beta-1 adrenergic receptor responsiveness in coronary arterioles following intravenous stromal vascular fraction therapy in aged rats. / 11.07.2019 / PubMed / Full text
Older Adults Exhibit Greater Visual Cortex Inhibition and Reduced Visual Cortex Plasticity Compared to Younger Adults. / 2019 / PubMed / Full text
Loss of Prefrontal Cortical Higher Cognition with Uncontrollable Stress: Molecular Mechanisms, Changes with Age, and Relevance to Treatment. / 17.05.2019 / PubMed / Full text
Study on neuroendocrine-immune function of Phenylethanoid Glycosides of Desertliving Cistanche herb in perimenopausal rat model. / 28.06.2019 / PubMed / Full text
Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model. / 06.2019 / PubMed / Full text
Androgens Ameliorate Impaired Ischemia-Induced Neovascularization Due to Aging in Male Mice. / 01.05.2019 / PubMed / Full text
Halogen-substituted anthranilic acid derivatives provide a novel chemical platform for androgen receptor antagonists. / 04.2019 / PubMed / Full text
ERK mediated survival signaling is dependent on the Gq-G-protein coupled receptor type and subcellular localization in adult cardiac myocytes. / 02.2019 / PubMed / Full text
Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue. / 02.2019 / PubMed / Full text
Androgen Receptor in Neurons Slows Age-Related Cortical Thinning in Male Mice. / 03.2019 / PubMed / Full text
The presbycardia phenotype: Cardiac remodeling and valvular degeneration in nonagenarians. / 12.2018 / PubMed / Full text
The androgen receptor is required for maintenance of bone mass in adult male mice. / 05.01.2019 / PubMed / Full text
Sympathetic neurotransmission in spleens from aging Brown-Norway rats subjected to reduced sympathetic tone. / 15.11.2018 / PubMed / Full text
Assessment of the Aging of the Brown Adipose Tissue by F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna . / 2018 / PubMed / Full text
Staging of amyloid β, t-tau, regional atrophy rates, and cognitive change in a nondemented cohort: Results of serial mediation analyses. / 2018 / PubMed / Full text
Aging of human alpha rhythm. / 09.2018 / PubMed / Full text
Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. / 01.08.2018 / PubMed / Full text
Dexmedetomidine attenuates renal fibrosis via α2-adrenergic receptor-dependent inhibition of cellular senescence after renal ischemia/reperfusion. / 15.08.2018 / PubMed / Full text
Cross talk between androgen and Wnt signaling potentially contributes to age-related skeletal muscle atrophy in rats. / 01.08.2018 / PubMed / Full text
Increase in random component of heart rate variability coinciding with developmental and degenerative stages of life. / 25.05.2018 / PubMed / Full text
Relationship between morphological development and sex hormone receptor expression of mammary glands with age in male rats. / 30.07.2018 / PubMed / Full text
Altered expression of hepatic β-adrenergic receptors in aging rats: implications for age-related metabolic dysfunction in liver. / 01.04.2018 / PubMed / Full text
Reproductive aging in male dogs: The epididymal sperm defects and expression of androgen receptor in reproductive tissues. / 01.03.2018 / PubMed / Full text
Iron status and oxidative stress in the aged rabbit heart. / 01.2018 / PubMed / Full text
Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. / 01.2018 / PubMed / Full text
Impact of HPV vaccination: health gains in the Italian female population. / 29.09.2017 / PubMed / Full text
The prevalence and progression of mild cognitive impairment among clinic and community populations: a systematic review and meta-analysis. / 10.2017 / PubMed / Full text
Age-related changes in sexual function and steroid-hormone receptors in the medial preoptic area of male rats. / 11.2017 / PubMed / Full text
Amalaki rasayana, a traditional Indian drug enhances cardiac mitochondrial and contractile functions and improves cardiac function in rats with hypertrophy. / 17.08.2017 / PubMed / Full text
The biological and clinical advances of androgen receptor function in age-related diseases and cancer [Review]. / 28.10.2017 / PubMed / Full text
Local Allergic Rhinitis in Adult Patients with Chronic Nasal Symptoms. / 2017 / PubMed / Full text

ATM

SATMF Suppresses the Premature Senescence Phenotype of the ATM Loss-of-Function Mutant and Improves Its Fertility in [i]Arabidopsis[/i]. / 30.10.2020 / PubMed / Full text
ATM mediated-p53 signaling pathway forms a novel axis for senescence control. / 11.2020 / PubMed / Full text
Non-canonical ATM/MRN activities temporally define the senescence secretory program. / 05.10.2020 / PubMed / Full text
ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging. / 22.03.2020 / PubMed / Full text
ATM suppresses leaf senescence triggered by DNA double-strand break through epigenetic control of senescence-associated genes in Arabidopsis. / 07.2020 / PubMed / Full text
Glioblastoma Cells Do Not Affect Axitinib-Dependent Senescence of HUVECs in a Transwell Coculture Model. / 21.02.2020 / PubMed / Full text
Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate. / 03.2020 / PubMed / Full text
BRCA-related ATM-mediated DNA double-strand break repair and ovarian aging. / 01.01.2020 / PubMed / Full text
ATM Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy. / 2019 / PubMed / Full text
SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress. / 12.2019 / PubMed / Full text
LncRNA RP11-670E13.6, interacted with hnRNPH, delays cellular senescence by sponging microRNA-663a in UVB damaged dermal fibroblasts. / 23.08.2019 / PubMed / Full text
Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase. / 10.2019 / PubMed / Full text
Curcumin induces multiple signaling pathways leading to vascular smooth muscle cell senescence. / 12.2019 / PubMed / Full text
Long-term culture of mesenchymal stem cells impairs ATM-dependent recognition of DNA breaks and increases genetic instability. / 29.07.2019 / PubMed / Full text
Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence. / 01.07.2019 / PubMed / Full text
Meeting report of the 14th Japan-Korea joint symposium on cancer and aging research: current status of translational research and approaches to precision medicine. / 05.2019 / PubMed / Full text
Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. / 2019 / PubMed / Full text
Alleviation of Senescence via ATM Inhibition in Accelerated Aging Models. / 31.03.2019 / PubMed / Full text
Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. / 01.05.2019 / PubMed / Full text
Genomic insult oriented mitochondrial instability and proliferative hindrance in the bone marrow of aplastic mice including stem/progenitor population. / 04.2019 / PubMed / Full text
N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ATM pathway. / 18.01.2019 / PubMed / Full text
Hydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced Cells and Suppresses Cellular Senescence. / 21.01.2019 / PubMed / Full text
Low dose dinaciclib enhances doxorubicin-induced senescence in myeloma RPMI8226 cells by transformation of the p21 and p16 pathways. / 11.2018 / PubMed / Full text
The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. / 2018 / PubMed / Full text
Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. / 05.11.2018 / PubMed / Full text
The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence. / 19.10.2018 / PubMed / Full text
Defenses against Pro-oxidant Forces - Maintenance of Cellular and Genomic Integrity and Longevity. / 10.2018 / PubMed / Full text
The ING1a model of rapid cell senescence. / 01.2019 / PubMed / Full text
Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo. / 08.2018 / PubMed / Full text
Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria. / 02.05.2018 / PubMed / Full text
Inflammation, a significant player of Ataxia-Telangiectasia pathogenesis? / 07.2018 / PubMed / Full text
Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence. / 30.04.2018 / PubMed / Full text
Senescence-messaging secretome factors trigger premature senescence in human endometrium-derived stem cells. / 19.02.2018 / PubMed / Full text
Bisphenol A induces DSB-ATM-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts. / 04.2018 / PubMed / Full text
Global mapping of transcription factor motifs in human aging. / 2018 / PubMed / Full text
Ataxia-Telangiectasia Mutated Modulation of Carbon Metabolism in Cancer. / 2017 / PubMed / Full text
DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system. / 05.2018 / PubMed / Full text
Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program. / 01.10.2017 / PubMed / Full text
A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress. / 10.08.2017 / PubMed / Full text

GFAP

Immunohistological Detection of Active Satellite Cellsin Rat Dorsal Root Ganglia after Parenteral Administration of Lipopolysaccharide and during Aging. / 09.2020 / PubMed / Full text
Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease. / 23.09.2020 / PubMed / Full text
ApoE Genotype-Dependent Response to Antioxidant and Exercise Interventions on Brain Function. / 25.06.2020 / PubMed / Full text
Age-Dependent Heterogeneity of Murine Olfactory Bulb Astrocytes. / 2020 / PubMed / Full text
Neuroinflammation in Aged Brain: Impact of the Oral Administration of Ellagic Acid Microdispersion. / 21.05.2020 / PubMed / Full text
Long-term treatment with spermidine increases health span of middle-aged Sprague-Dawley male rats. / 06.2020 / PubMed / Full text
Meta-analysis of human prefrontal cortex reveals activation of GFAP and decline of synaptic transmission in the aging brain. / 05.03.2020 / PubMed / Full text
Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA-mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain. / 09.2020 / PubMed / Full text
Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy. / 12.02.2020 / PubMed / Full text
Lipopolysaccharide exposure during late embryogenesis triggers and drives Alzheimer-like behavioral and neuropathological changes in CD-1 mice. / 03.2020 / PubMed / Full text
Increased levels of Aβ42 decrease the lifespan of ob/ob mice with dysregulation of microglia and astrocytes. / 02.2020 / PubMed / Full text
Selective brain neuronal and glial losses without changes in GFAP immunoreactivity: Young versus mature adult Wistar rats. / 09.2019 / PubMed / Full text
Expression of p16 and p21 in the frontal association cortex of ALS/MND brains suggests neuronal cell cycle dysregulation and astrocyte senescence in early stages of the disease. / 02.2020 / PubMed / Full text
Deficiency of Yes-Associated Protein Induces Cataract in Mice. / 04.2019 / PubMed / Full text
Comparison of multi-tissue aging between human and mouse. / 17.04.2019 / PubMed / Full text
Chemotherapy accelerates age-related development of tauopathy and results in loss of synaptic integrity and cognitive impairment. / 07.2019 / PubMed / Full text
Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS. / 2019 / PubMed / Full text
Tactile Stimulation on Adulthood Modifies the HPA Axis, Neurotrophic Factors, and GFAP Signaling Reverting Depression-Like Behavior in Female Rats. / 09.2019 / PubMed / Full text
JNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy. / 08.2019 / PubMed / Full text
Investigating Age-Related Changes in Proliferation and the Cell Division Repertoire of Parenchymal Reactive Astrocytes. / 2019 / PubMed / Full text
Unexpected Exacerbation of Neuroinflammatory Response After a Combined Therapy in Old Parkinsonian Mice. / 2018 / PubMed / Full text
Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees. / 01.05.2019 / PubMed / Full text
Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?: A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats. / 02.2019 / PubMed / Full text
AP-1 and the injury response of the GFAP gene. / 02.2019 / PubMed / Full text
Differential expression of a stress-regulated gene Nr4a2 characterizes early- and late-born hippocampal granule cells. / 06.2019 / PubMed / Full text
Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice. / 04.09.2018 / PubMed / Full text
Cannabinoid 1 receptor signaling on GABAergic neurons influences astrocytes in the ageing brain. / 2018 / PubMed / Full text
Disappearance of cerebrovascular laminin immunoreactivity as related to the maturation of astroglia in rat brain. / 10.2018 / PubMed / Full text
Inhibition of the RhoGTPase Cdc42 by ML141 enhances hepatocyte differentiation from human adipose-derived mesenchymal stem cells via the Wnt5a/PI3K/miR-122 pathway: impact of the age of the donor. / 19.06.2018 / PubMed / Full text
The neuropeptide-12 improves recognition memory and neuronal plasticity of the limbic system in old rats. / 08.2018 / PubMed / Full text
Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury. / 01.2019 / PubMed / Full text
Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. / 01.08.2018 / PubMed / Full text
Aging-related tau astrogliopathy (ARTAG): not only tau phosphorylation in astrocytes. / 11.2018 / PubMed / Full text
Aberrant astrocyte Ca signals "AxCa signals" exacerbate pathological alterations in an Alexander disease model. / 05.2018 / PubMed / Full text
Markers of Alzheimer's Disease in Primary Visual Cortex in Normal Aging in Mice. / 2017 / PubMed / Full text
Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. / 12.2017 / PubMed / Full text
Suppression of neuroinflammation by matrix metalloproteinase-8 inhibitor in aged normal and LRRK2 G2019S Parkinson's disease model mice challenged with lipopolysaccharide. / 18.11.2017 / PubMed / Full text
The metabolic and neuroinflammatory changes induced by consuming a cafeteria diet are age-dependent. / 04.2019 / PubMed / Full text
Thymosin β4 for the treatment of acute stroke in aged rats. / 17.10.2017 / PubMed / Full text

TH

Thyroid hormone signaling is associated with physical performance, muscle mass, and strength in a cohort of oldest-old: results from the Mugello study. / 21.11.2020 / PubMed / Full text
Social Environment Ameliorates Behavioral and Immune Impairments in Tyrosine Hydroxylase Haploinsufficient Female Mice. / 09.08.2020 / PubMed / Full text
Mechanism of thyroid hormone signaling in skeletal muscle of aging mice. / 27.07.2020 / PubMed / Full text
Longitudinal changes in bone mineral density and trabecular bone score in Korean adults: a community-based prospective study. / 03.07.2020 / PubMed / Full text
Quantitative proteomic profiling of the rat substantia nigra places glial fibrillary acidic protein at the hub of proteins dysregulated during aging: Implications for idiopathic Parkinson's disease. / 07.2020 / PubMed / Full text
Withaferin-A Protects the Nigral Dopamine Neuron and Recovers Motor Activity in Aged Rats. / 2019 / PubMed / Full text
Effects of physical activity on bone mineral density in older adults: Korea National Health and Nutrition Examination Survey, 2008-2011. / 26.10.2019 / PubMed / Full text
Age-Related Resistance to Thyroid Hormone Action. / 11.2019 / PubMed / Full text
Age-Dependent Changes in Glucose Homeostasis in Male Deiodinase Type 2 Knockout Zebrafish. / 01.11.2019 / PubMed / Full text
Age effect on thyroid hormone brain response in male mice. / 12.2019 / PubMed / Full text
Aging Is Associated with Low Thyroid State and Organ-Specific Sensitivity to Thyroxine. / 12.2019 / PubMed / Full text
Age-Associated Dopaminergic Neuron Loss and Midbrain Glia Cell Phenotypic Polarization. / 01.09.2019 / PubMed / Full text
Age-Related Decrease in Tyrosine Hydroxylase Immunoreactivity in the Substantia Nigra and Region-Specific Changes in Microglia Morphology in HIV-1 Tg Rats. / 10.2019 / PubMed / Full text
An experimental model of Braak's pretangle proposal for the origin of Alzheimer's disease: the role of locus coeruleus in early symptom development. / 03.07.2019 / PubMed / Full text
The age modification to leukocyte telomere length effect on bone mineral density and osteoporosis among Chinese elderly women. / 11.2019 / PubMed / Full text
Regeneration of Dopaminergic Neurons in Adult Zebrafish Depends on Immune System Activation and Differs for Distinct Populations. / 12.06.2019 / PubMed / Full text
Oxidative-Inflammatory Stress in Immune Cells from Adult Mice with Premature Aging. / 12.02.2019 / PubMed / Full text
Aging Alters Phenotypic Traits of Thyroid Dysfunction in Male Mice With Divergent Effects on Complex Systems but Preserved Thyroid Hormone Action in Target Organs. / 12.07.2019 / PubMed / Full text
Association of bone mineral density with hemoglobin and change in hemoglobin among older men and women: The Cardiovascular Health Study. / 03.2019 / PubMed / Full text
Applications for non-invasive thyroid hormone measurements in mammalian ecology, growth, and maintenance. / 09.2018 / PubMed / Full text
Tyrosine Hydroxylase Inhibition in Substantia Nigra Decreases Movement Frequency. / 04.2019 / PubMed / Full text
The Association between Daytime Napping Characteristics and Bone Mineral Density in Elderly Thai Women without Osteoporosis. / 03.07.2018 / PubMed / Full text
Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice. / 08.2018 / PubMed / Full text
Pattern of tyrosine hydroxylase expression during aging of mesolimbic pathway of the rat. / 10.2018 / PubMed / Full text
Prolonged increase in ser31 tyrosine hydroxylase phosphorylation in substantia nigra following cessation of chronic methamphetamine. / 07.2018 / PubMed / Full text
Noni (Morinda citrifolia L.) fruit juice delays immunosenescence in the lymphocytes in lymph nodes of old F344 rats. / 05.2018 / PubMed / Full text
Dietary and Endocrine Regulation of Endogenous Hydrogen Sulfide Production: Implications for Longevity. / 01.06.2018 / PubMed / Full text
Neural Stem Cell Grafts Promote Astroglia-Driven Neurorestoration in the Aged Parkinsonian Brain via Wnt/β-Catenin Signaling. / 08.2018 / PubMed / Full text
Phosphorylated α-Synuclein Accumulations and Lewy Body-like Pathology Distributed in Parkinson's Disease-Related Brain Areas of Aged Rhesus Monkeys Treated with MPTP. / 21.05.2018 / PubMed / Full text
Premature aging in behavior and immune functions in tyrosine hydroxylase haploinsufficient female mice. A longitudinal study. / 03.2018 / PubMed / Full text
Sex-specific phenotypes of hyperthyroidism and hypothyroidism in aged mice. / 22.12.2017 / PubMed / Full text
Changes in neurofilament 200 and tyrosine hydroxylase expression in the cardiac innervation of diabetic rats during aging. / 01-02.2018 / PubMed / Full text
Aging-related limit of exercise efficacy on motor decline. / 2017 / PubMed / Full text
Regional Distribution of Longevity Population and Elements in Drinking Water in Jiangjin District, Chongqing City, China. / 08.2018 / PubMed / Full text
Age-dependent association of thyroid function with brain morphology and microstructural organization: evidence from brain imaging. / 01.2018 / PubMed / Full text
The Circadian Clock Gene Bmal1 Controls Thyroid Hormone-Mediated Spectral Identity and Cone Photoreceptor Function. / 17.10.2017 / PubMed / Full text
The Noradrenergic System of Aged GDNF Heterozygous Mice. / 04.2003 / PubMed / Full text
Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats. / 03.2018 / PubMed / Full text
Neuroprotective Effects of Intranasal IGF-1 against Neonatal Lipopolysaccharide-Induced Neurobehavioral Deficits and Neuronal Inflammation in the Substantia Nigra and Locus Coeruleus of Juvenile Rats. / 2017 / PubMed / Full text

CA3

Features of Postnatal Hippocampal Development in a Rat Model of Sporadic Alzheimer's Disease. / 2020 / PubMed / Full text
Age-Related Changes in Synaptic Plasticity Associated with Mossy Fiber Terminal Integration during Adult Neurogenesis. / 05-06.2020 / PubMed / Full text
Metabotropic Glutamate Receptors at the Aged Mossy Fiber - CA3 Synapse of the Hippocampus. / 07.01.2020 / PubMed / Full text
GABA Receptors Are Well Preserved in the Hippocampus of Aged Mice. / 07-08.2019 / PubMed / Full text
Cellular and Molecular Differences Between Area CA1 and the Dentate Gyrus of the Hippocampus. / 09.2019 / PubMed / Full text
Establishment of Novel Murine Model showing Vascular Inflammation-derived Cognitive Dysfunction. / 11.03.2019 / PubMed / Full text
p16 deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence. / 09.2019 / PubMed / Full text
Cyclohexane Inhalation Produces Long-Lasting Alterations in the Hippocampal Integrity and Reward-Seeking Behavior in the Adult Mouse. / 04.2019 / PubMed / Full text
Experience-Dependent Effects of Muscimol-Induced Hippocampal Excitation on Mnemonic Discrimination. / 2018 / PubMed / Full text
Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees. / 01.05.2019 / PubMed / Full text
Melatonin Influences Structural Plasticity in the Axons of Granule Cells in the Dentate Gyrus of Balb/C Mice. / 25.12.2018 / PubMed / Full text
Alzheimer's Disease Biomarkers Have Distinct Associations with Specific Hippocampal Subfield Volumes. / 2018 / PubMed / Full text
Early disruption of parvalbumin expression and perineuronal nets in the hippocampus of the Tg2576 mouse model of Alzheimer's disease can be rescued by enriched environment. / 12.2018 / PubMed / Full text
Susceptibility to hippocampal kindling seizures is increased in aging C57 black mice. / 12.2017 / PubMed / Full text
[AGE-RELATED CHANGES IN THE MORPHOMETRIC PARAMETERS OF THE NEURONS IN HUMAN HIPPOCAMPUS]. / 2016 / PubMed
Microglia changes associated to Alzheimer's disease pathology in aged chimpanzees. / 15.12.2018 / PubMed / Full text
Premarin has opposing effects on spatial learning, neural activation, and serum cytokine levels in middle-aged female rats depending on reproductive history. / 10.2018 / PubMed / Full text
Nonsteroidal anti-inflammatory drug, indomethacin improves spatial memory and NMDA receptor function in aged animals. / 10.2018 / PubMed / Full text
Biospectroscopic Imaging Provides Evidence of Hippocampal Zn Deficiency and Decreased Lipid Unsaturation in an Accelerated Aging Mouse Model. / 21.11.2018 / PubMed / Full text
Trimethylamine-N-oxide promotes brain aging and cognitive impairment in mice. / 08.2018 / PubMed / Full text
Dynamic SAP102 expression in the hippocampal subregions of rats and APP/PS1 mice of various ages. / 06.2018 / PubMed / Full text
Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization. / 05.2018 / PubMed / Full text
Stereological Analysis of Microglia in Aged Male and Female Fischer 344 Rats in Socially Relevant Brain Regions. / 01.05.2018 / PubMed / Full text
GPR30 activation improves memory and facilitates DHPG-induced LTD in the hippocampal CA3 of middle-aged mice. / 03.2018 / PubMed / Full text
Neurodevelopment and behavior in neonatal OXYS rats with genetically determined accelerated senescence. / 15.02.2018 / PubMed / Full text
Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment. / 2017 / PubMed / Full text
Excitatory Synaptic Input to Hilar Mossy Cells under Basal and Hyperexcitable Conditions. / 11-12.2017 / PubMed / Full text
Age-related vulnerability of pattern separation in C57BL/6J mice. / 02.2018 / PubMed / Full text
Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease. / 01.2018 / PubMed / Full text
Time of day but not aging regulates 5-HT receptor binding sites in the hamster hippocampus. / 01.01.2018 / PubMed / Full text
Cytoarchitectonically-driven MRI atlas of nonhuman primate hippocampus: Preservation of subfield volumes in aging. / 05.2019 / PubMed / Full text
The impact of ageing reveals distinct roles for human dentate gyrus and CA3 in pattern separation and object recognition memory. / 25.10.2017 / PubMed / Full text
Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils. / 09.2017 / PubMed / Full text
Dopamine D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice. / 12.2017 / PubMed / Full text
Gpr158 mediates osteocalcin's regulation of cognition. / 02.10.2017 / PubMed / Full text
Critical periods regulating the circuit integration of adult-born hippocampal neurons. / 01.2018 / PubMed / Full text
Attenuated Activity across Multiple Cell Types and Reduced Monosynaptic Connectivity in the Aged Perirhinal Cortex. / 13.09.2017 / PubMed / Full text
Distribution of corticotropin-releasing factor receptor 1 in the developing mouse forebrain: A novel sex difference revealed in the rostral periventricular hypothalamus. / 11.10.2017 / PubMed / Full text

CGA

Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric assessment: A planned interim analysis of a multicenter, phase II trial. / 04.11.2020 / PubMed / Full text
The Protective Effect of Chlorogenic Acid on Vascular Senescence via the Nrf2/HO-1 Pathway. / 25.06.2020 / PubMed / Full text
Association between comprehensive geriatric assessment and short-term outcomes among older adult patients with stroke: A nationwide retrospective cohort study using propensity score and instrumental variable methods. / 06.2020 / PubMed / Full text
Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis. / 12.2020 / PubMed / Full text
A Computerized Frailty Assessment Tool at Points-of-Care: Development of a Standalone Electronic Comprehensive Geriatric Assessment/Frailty Index (eFI-CGA). / 2020 / PubMed / Full text
Allocating patients to geriatric medicine wards in a tertiary university hospital in England: A service evaluation of the Specialist Advice for the Frail Elderly (SAFE) team. / 09.2018 / PubMed / Full text
Role of Frailty on Risk Stratification in Cardiac Surgery and Procedures. / 2020 / PubMed / Full text
Developing an objective structured clinical examination in comprehensive geriatric assessment - A pilot study. / 05-08.2019 / PubMed / Full text
How do doctors choose treatment for older gynecological cancer patients? A Japanese Gynecologic Oncology Group survey of gynecologic oncologists. / 04.2020 / PubMed / Full text
Validation of the Pictorial Fit-Frail Scale in a memory clinic setting. / 09.2020 / PubMed / Full text
Impact of Resolution of Hyponatremia on Neurocognitive and Motor Performance in Geriatric Patients. / 29.08.2019 / PubMed / Full text
Health outcome of older hospitalized patients in internal medicine environments evaluated by Identification of Seniors at Risk (ISAR) screening and geriatric assessment. / 14.08.2019 / PubMed / Full text
What will perioperative geriatric assessment for older cancer patients look like in 2025? Advantages and limitations of new technologies in geriatric assessment. / 03.2020 / PubMed / Full text
Impact of comprehensive geriatric assessment on short-term mortality in older patients with cancer-a follow-up study. / 07.2019 / PubMed / Full text
Comprehensive Geriatric Assessment in the perioperative setting; where next? / 01.09.2019 / PubMed / Full text
Use of comprehensive geriatric assessment (CGA) to define frailty in geriatric oncology: Searching for the best threshold. Cross-sectional study of 418 old patients with cancer evaluated in the Geriatric Frailty Clinic (G.F.C.) of Toulouse (France). / 11.2019 / PubMed / Full text
The prognostic significance of geriatric syndromes and resources. / 01.2020 / PubMed / Full text
Functional status in a geriatric oncology setting: A review. / 11.2019 / PubMed / Full text
Changes in the Use of Comprehensive Geriatric Assessment in Clinical Trials for Older Patients with Cancer over Time. / 08.2019 / PubMed / Full text
Predictive values of two frailty screening tools in older patients with solid cancer: a comparison of SAOP2 and G8. / 12.10.2018 / PubMed / Full text
New associations of the Multidimensional Prognostic Index. / 08.2019 / PubMed / Full text
Is care based on comprehensive geriatric assessment with mobile teams better than usual care? A study protocol of a randomised controlled trial (The GerMoT study). / 10.10.2018 / PubMed / Full text
[The Comprehensive Geriatric Assessment predicts healthy life expectancy better than health checkups in older people: JAGES cohort study]. / 2018 / PubMed / Full text
Outpatient comprehensive geriatric assessment: effects on frailty and mortality in old people with multimorbidity and high health care utilization. / 04.2019 / PubMed / Full text
Beyond the black box of geriatric assessment: Understanding enhancements to care by the geriatric oncology clinic. / 11.2018 / PubMed / Full text
General recommendations paper on the management of older patients with cancer: the SEOM geriatric oncology task force's position statement. / 10.2018 / PubMed / Full text
Delirium, Frailty, and Fast-Track Surgery in Oncogeriatrics: Is There a Link? / 01-04.2018 / PubMed / Full text
Screening for cognitive impairment in an Australian aged care assessment team as part of comprehensive geriatric assessment. / 05.2019 / PubMed / Full text
Comprehensive Geriatric Assessment in the Older Adult with Cancer: A Review. / 10.2017 / PubMed / Full text
Frailty: A global measure of the multisystem impact of COPD. / 11.2018 / PubMed / Full text
Delphi consensus of an expert committee in oncogeriatrics regarding comprehensive geriatric assessment in seniors with cancer in Spain. / 07.2018 / PubMed / Full text
The added value of clinical geriatric assessment prior to geriatric rehabilitation. / 12.2017 / PubMed
What is Comprehensive Geriatric Assessment (CGA)? An umbrella review. / 01.01.2018 / PubMed / Full text
[Geriatric assessment and prognostic scores in older cancer patient: Additional support to the therapeutic decision?] / 11.2017 / PubMed / Full text
Preadmission Functional Decline Predicts Functional Improvement Among Older Patients Admitted to Acute Care Hospital. / 11.09.2018 / PubMed / Full text
Towards a biological geriatric assessment. / 01.07.2018 / PubMed / Full text
The potential clinical benefits of medicines optimisation through comprehensive geriatric assessment, carried out by secondary care geriatricians, in a general practice care setting in North Staffordshire, UK: a feasibility study. / 28.09.2017 / PubMed / Full text
New horizons in comprehensive geriatric assessment. / 01.09.2017 / PubMed / Full text

CP

A Life Course Perspective on Growing Older With Cerebral Palsy. / 19.11.2020 / PubMed / Full text
The molecular anatomy and functions of the choroid plexus in healthy and diseased brain. / 01.11.2020 / PubMed / Full text
The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation. / 09.2020 / PubMed / Full text
Model based strategies towards protein A resin lifetime optimization and supervision. / 16.08.2020 / PubMed / Full text
The influence of age and environmental conditions on supplement intake by beef cattle winter grazing northern mixed-grass rangelands. / 01.07.2020 / PubMed / Full text
Cyclophosphamide, a cancer chemotherapy drug-induced early onset of reproductive senescence and alterations in reproductive performance and their prevention in mice. / 15.06.2020 / PubMed / Full text
Asymptomatic [i]Clostridium perfringens[/i] Inhabitation in Intestine Can Cause Inflammation, Apoptosis, and Disorders in Brain. / 01.2020 / PubMed / Full text
The Role of the Clinical Pharmacist in the Management of People Living with HIV in the Modern Antiretroviral Era. / 2019 / PubMed / Full text
A clinically feasible method for the assessment and characterization of pain in patients with chronic pancreatitis. / 01.2020 / PubMed / Full text
Differences in geometric strength at the contralateral hip between men with hip fracture and non-fractured comparators. / 03.2020 / PubMed / Full text
Factors associated with the number of clinical pharmacy recommendations: findings from an observational study in geriatric inpatients. / 23.10.2019 / PubMed / Full text
Protection against oxidative stress and anti-aging effect in Drosophila of royal jelly-collagen peptide. / 01.2020 / PubMed / Full text
Prevalence of drooling, swallowing, and feeding problems in cerebral palsy across the lifespan: a systematic review and meta-analyses. / 11.2019 / PubMed / Full text
Longitudinal Development of Receptive Vocabulary in Children with Cerebral Palsy and Anarthria: Use of the MacArthur-Bates CDI. / 07.2020 / PubMed / Full text
[Problem of mineral insufficiency at chronic pancreatitis in dependence on age]. / 2019 / PubMed / Full text
Systemic inflammation contributes to impairment of quality of life in chronic pancreatitis. / 13.05.2019 / PubMed / Full text
A Genotypic Comparison Reveals That the Improvement in Nitrogen Remobilization Efficiency in Oilseed Rape Leaves Is Related to Specific Patterns of Senescence-Associated Protease Activities and Phytohormones. / 2019 / PubMed / Full text
Keeping a 'watch-full' eye on metabolic disease. / 07.2013 / PubMed / Full text
Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. / 2018 / PubMed / Full text
Radiologic changes in the aging nasal cavity. / 01.04.2019 / PubMed / Full text
Influence of various concentrate-to-roughage ratios on dietary intake and nutrient digestibilities of weanling horses. / 01.2019 / PubMed / Full text
Ameliorative effect of zinc oxide nanoparticles on cyclophosphamide induced testicular injury in adult rat. / 10.2018 / PubMed / Full text
A Brain without Brakes: Reduced Inhibition Is Associated with Enhanced but Dysregulated Plasticity in the Aged Rat Auditory Cortex. / 07-08.2018 / PubMed / Full text
Energy expenditure is associated with age, anthropometric indicators and body composition in children with spastic cerebral palsy. / 02.08.2018 / PubMed / Full text
Microstructure and selected mechanical properties of aged Ti-15Zr-based alloys for biomedical applications. / 01.10.2018 / PubMed / Full text
The Impact of Aging, Psychotic Symptoms, Medication, and Brain-Derived Neurotrophic Factor on Cognitive Impairment in Japanese Chronic Schizophrenia Patients. / 2018 / PubMed / Full text
CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length. / 08.2018 / PubMed / Full text
Health conditions, functional status and health care utilization in adults with cerebral palsy. / 12.12.2018 / PubMed / Full text
Age-related Changes in Postural Sway During Sit-to-stand in Typical Children and Children with Cerebral Palsy. / 2019 / PubMed / Full text
The choroid plexus is an important circadian clock component. / 14.03.2018 / PubMed / Full text
Early development and reproductive lifespan of rabbit females: implications of growth rate, rearing diet and body condition at first mating. / 11.2018 / PubMed / Full text
Functional Capacity in Adults With Cerebral Palsy: Lower Limb Muscle Strength Matters. / 05.2018 / PubMed / Full text
Investigation of Petal Senescence by TRV-Mediated Virus-Induced Gene Silencing in Rose. / 2018 / PubMed / Full text
Immediate and late effects of chronic stress in the testes of prepubertal and adult rats. / 07-08.2018 / PubMed / Full text
Age related changes in balance performance during self-selected and narrow stance testing. / 03-04.2018 / PubMed / Full text
EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development. / 02.2018 / PubMed / Full text
The Effect of Insecticidal Stress on Reproductive Output of Susceptible and Field Strains of Aedes aegypti (Diptera: Culicidae). / 10.01.2018 / PubMed / Full text

SOD2

Astaxanthin Counteracts Vascular Calcification In Vitro Through an Early Up-Regulation of SOD2 Based on a Transcriptomic Approach. / 12.11.2020 / PubMed / Full text
Alginate Oligosaccharide Prevents against D-galactose-mediated Cataract in C57BL/6J Mice via Regulating Oxidative Stress and Antioxidant System. / 06.11.2020 / PubMed / Full text
Protoflavones in melanoma therapy: Prooxidant and pro-senescence effect of protoapigenone and its synthetic alkyl derivative in A375 cells. / 01.11.2020 / PubMed / Full text
Ginsenoside Rg1 protects against Sca-1 HSC/HPC cell aging by regulating the SIRT1-FOXO3 and SIRT3-SOD2 signaling pathways in a γ-ray irradiation-induced aging mice model. / 08.2020 / PubMed / Full text
Almond Skin Extracts and Chlorogenic Acid Delay Chronological Aging and Enhanced Oxidative Stress Response in Yeast. / 28.05.2020 / PubMed / Full text
Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish. / 19.05.2020 / PubMed / Full text
Bioactive peptides derived from crimson snapper and in vivo anti-aging effects on fat diet-induced high fat Drosophila melanogaster. / 29.01.2020 / PubMed / Full text
Ellagic acid prolongs the lifespan of Drosophila melanogaster. / 02.2020 / PubMed / Full text
Chlorella vulgaris modulates the expression of senescence-associated genes in replicative senescence of human diploid fibroblasts. / 01.2020 / PubMed / Full text
Age-Associated Changes in Antioxidants and Redox Proteins of Rat Heart. / 30.12.2019 / PubMed / Full text
Impact of curcumin on replicative and chronological aging in the Saccharomyces cerevisiae yeast. / 02.2020 / PubMed / Full text
Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice. / 2019 / PubMed / Full text
Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin. / 2019 / PubMed / Full text
Preventive effect of Lactobacillus plantarum KSFY02 isolated from naturally fermented yogurt from Xinjiang, China, on d-galactose-induced oxidative aging in mice. / 07.2019 / PubMed / Full text
Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway. / 07.2019 / PubMed / Full text
Sex differences in the aging human heart: decreased sirtuins, pro-inflammatory shift and reduced anti-oxidative defense. / 08.04.2019 / PubMed / Full text
NKT-like cells reveal higher than T lymphocytes expression of cellular protective proteins HSP70 and SOD2 and comparably increased expression of SIRT1 in the oldest seniors. / 2018 / PubMed / Full text
Ku86 alleviates human umbilical vein endothelial cellular apoptosis and senescence induced by a low dose of ionizing radiation. / 02.2019 / PubMed / Full text
Putrescine delays postovulatory aging of mouse oocytes by upregulating PDK4 expression and improving mitochondrial activity. / 16.12.2018 / PubMed / Full text
CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2. / 2018 / PubMed / Full text
Functional restoration of replicative senescent mesenchymal stem cells by the brown alga [i]Undaria pinnatifida[/i]. / 2017 / PubMed / Full text
[i]Lactobacillus plantarum[/i] CQPC11 Isolated from Sichuan Pickled Cabbages Antagonizes d-galactose-Induced Oxidation and Aging in Mice. / 20.11.2018 / PubMed / Full text
Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage. / 2018 / PubMed / Full text
Reactive oxygen species, aging and articular cartilage homeostasis. / 20.02.2019 / PubMed / Full text
Cytokine modulation, oxidative stress and thymic dysfunctions: Role of age-related changes in the experimental Trypanosoma cruzi infection: Age-related thymic dysfunctions and Trypanosoma cruzi infection. / 11.2018 / PubMed / Full text
Mitohormesis in Mice via Sustained Basal Activation of Mitochondrial and Antioxidant Signaling. / 06.11.2018 / PubMed / Full text
Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls. / 10.2018 / PubMed / Full text
Age-related changes in vascular responses to angiotensin-(1-7) in female mice. / 07-09.2018 / PubMed / Full text
Effect of β-D-Mannuronic Acid (M2000) on Oxidative Stress Enzymes' Gene Using Healthy Donor Peripheral Blood Mononuclear Cells for Evaluating the Anti-Aging Property. / 2019 / PubMed / Full text
The impact of preserved Klotho gene expression on antioxidative stress activity in healthy kidney. / 01.08.2018 / PubMed / Full text
Age-related NMDA signaling alterations in SOD2 deficient mice. / 06.2018 / PubMed / Full text
Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging-associated olfactory circuit degeneration in [i]Drosophila[/i]. / 18.01.2018 / PubMed / Full text
Ultrafine particulate matter exposure impairs vasorelaxant response in superoxide dismutase 2-deficient murine aortic rings. / 2018 / PubMed / Full text
COCOA (Theobroma cacao) Polyphenol-Rich Extract Increases the Chronological Lifespan of Saccharomyces cerevisiae. / 2016 / PubMed
Yeast polyubiquitin gene UBI4 deficiency leads to early induction of apoptosis and shortened replicative lifespan. / 07.2018 / PubMed / Full text
Time-response characteristic and potential biomarker identification of heavy metal induced toxicity in zebrafish. / 01.2018 / PubMed / Full text
Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats. / 11.2017 / PubMed / Full text

HGS

Handgrip strength asymmetry is associated with future falls in older Americans. / 27.11.2020 / PubMed / Full text
Examining Additional Aspects of Muscle Function with a Digital Handgrip Dynamometer and Accelerometer in Older Adults: A Pilot Study. / 31.10.2020 / PubMed / Full text
The Relationship between Muscular Strength and Depression in Older Adults with Chronic Disease Comorbidity. / 18.09.2020 / PubMed / Full text
Handgrip Strength in the Korean Population: Normative Data and Cutoff Values. / 12.2019 / PubMed / Full text
Handgrip Strength Asymmetry and Weakness Are Associated with Lower Cognitive Function: A Panel Study. / 09.2020 / PubMed / Full text
Handgrip Strength Asymmetry and Weakness are Differentially Associated with Functional Limitations in Older Americans. / 06.05.2020 / PubMed / Full text
Absolute and Body Mass Index Normalized Handgrip Strength Percentiles by Gender, Ethnicity, and Hand Dominance in Americans. / 2020 / PubMed / Full text
Hand grip strength variability during serial testing as an entropic biomarker of aging: a Poincaré plot analysis. / 13.01.2020 / PubMed / Full text
Physical Activity and Fitness in White- and Blue-Collar Retired Men. / 11-12.2019 / PubMed / Full text
Association between Hand Grip Strength and Self-Rated Health in Middle- and Old-Aged Korean Citizens. / 01.2020 / PubMed / Full text
Weakness May Have a Causal Association With Early Mortality in Older Americans: A Matched Cohort Analysis. / 05.2020 / PubMed / Full text
Associations Between Dietary Patterns and Handgrip Strength: The Korea National Health and Nutrition Examination Survey 2014-2016. / 08.2020 / PubMed / Full text
Effect of relative handgrip strength on cardiovascular disease among Korean adults aged 45 years and older: Results from the Korean Longitudinal Study of Aging (2006-2016). / 01-02.2020 / PubMed / Full text
Weakness and cognitive impairment are independently and jointly associated with functional decline in aging Americans. / 09.2020 / PubMed / Full text
Association of phase angle with sarcopenia and its components in physically active older women. / 08.2020 / PubMed / Full text
Age- and sex-related differences in muscle strength and physical performance in older Chinese. / 05.2020 / PubMed / Full text
Decreased Handgrip Strength is Associated With Impairments in Each Autonomous Living Task for Aging Adults in the United States. / 2019 / PubMed / Full text
The impact of muscle function, muscle mass and sarcopenia on independent ageing in very old Swedish men. / 29.05.2019 / PubMed / Full text
Nutritional status of older patients on hemodialysis: Which nutritional markers can best predict clinical outcomes? / 09.2019 / PubMed / Full text
Handgrip strength, depression, and all-cause mortality in Korean older adults. / 03.05.2019 / PubMed / Full text
Handgrip Strength of World Trade Center (WTC) Responders: The Role of Re-Experiencing Posttraumatic Stress Disorder (PTSD) Symptoms. / 29.03.2019 / PubMed / Full text
Vitamin D is related to handgrip strength in adult men aged 50 years and over: A population study from the TCLSIH cohort study. / 05.2019 / PubMed / Full text
Reference data on hand grip and lower limb strength using the Nintendo Wii balance board: a cross-sectional study of 354 subjects from 20 to 99 years of age. / 12.01.2019 / PubMed / Full text
Determining functional activity profiles in patients with upper extremity disorders: is there effect modification by hand-grip strength? / 2018 / PubMed / Full text
Hand grip strength as a physical biomarker of aging from the perspective of a Fibonacci mathematical modeling. / 29.11.2018 / PubMed / Full text
Body image satisfaction, sociodemographic, functional and clinical aspects of community-dwelling older adults. / 07-09.2018 / PubMed / Full text
Orthostatic hypotension and physical functioning in older adults: A systematic review and meta-analysis. / 12.2018 / PubMed / Full text
Inverse relationship between serum hsCRP concentration and hand grip strength in older adults: a nationwide population-based study. / 16.08.2018 / PubMed / Full text
Association of Anthropometric and Nutrition Status Indicators with Hand Grip Strength and Gait Speed in Older Adults. / 03.2019 / PubMed / Full text
Handgrip Strength and Health in Aging Adults. / 09.2018 / PubMed / Full text
Hand grip strength as a predictor of postoperative complications in esophageal cancer patients undergoing esophagectomy. / 01.2018 / PubMed / Full text
Age-related declines in the swallowing muscle strength of men and women aged 20-89 years: A cross-sectional study on tongue pressure and jaw-opening force in 980 subjects. / 09-10.2018 / PubMed / Full text
Association between handgrip strength, balance, and knee flexion/extension strength in older adults. / 2018 / PubMed / Full text
Movement velocity in the chair squat is associated with measures of functional capacity and cognition in elderly people at low risk of fall. / 2018 / PubMed / Full text
Inverse Association Between Height-Increasing Alleles and Extreme Longevity in Japanese Women. / 17.04.2018 / PubMed / Full text
Hand-grip strength among older adults in Singapore: a comparison with international norms and associative factors. / 04.08.2017 / PubMed / Full text

TERT

Telomeres and telomerase in risk assessment of cardiovascular diseases. / 15.12.2020 / PubMed / Full text
A 4-Base-Pair Core-Enclosing Helix in Telomerase RNA Is Essential for Activity and for Binding to the Telomerase Reverse Transcriptase Catalytic Protein Subunit. / 20.11.2020 / PubMed / Full text
Angiotensin inhibition and cellular senescence in the developing rat kidney. / 12.2020 / PubMed / Full text
Decreased expression of TERT and telomeric proteins as human ovaries age may cause telomere shortening. / 27.08.2020 / PubMed / Full text
The secrets of telomerase: Retrospective analysis and future prospects. / 15.09.2020 / PubMed / Full text
Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides. / 06.2020 / PubMed / Full text
Unravelling Cellular Mechanisms of Stem Cell Senescence: An Aid from Natural Bioactive Molecules. / 20.03.2020 / PubMed / Full text
Expression of telomerase reverse transcriptase positively correlates with duration of lithium treatment in bipolar disorder. / 04.2020 / PubMed / Full text
FAM96B inhibits the senescence of dental pulp stem cells. / 05.2020 / PubMed / Full text
Aging and biomarkers: Transcriptional levels evaluation of Osteopontin/miRNA-181a axis in hepatic tissue of rats in different age ranges. / 05.2020 / PubMed / Full text
Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells. / 04.2020 / PubMed / Full text
Characterization of human telomerase reverse transcriptase immortalized anterior cruciate ligament cell lines. / 12.2019 / PubMed / Full text
Mitochondria, Telomeres and Telomerase Subunits. / 2019 / PubMed / Full text
Towards Therapeutic Alternatives for Mercury Neurotoxicity in the Amazon: Unraveling the Pre-Clinical Effects of the Superfruit Açaí ([i]Euterpe oleracea[/i], Mart.) as Juice for Human Consumption. / 26.10.2019 / PubMed / Full text
Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing. / 08.10.2019 / PubMed / Full text
Telomerase Biology Associations Offer Keys to Cancer and Aging Therapeutics. / 2020 / PubMed / Full text
Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts. / 17.09.2019 / PubMed / Full text
TERT assists GDF11 to rejuvenate senescent VEGFR2 /CD133 cells in elderly patients with myocardial infarction. / 11.2019 / PubMed / Full text
Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with Epigenetics. / 07.07.2019 / PubMed / Full text
Role of Senescence and Neuroprotective Effects of Telomerase in Neurodegenerative Diseases. / 04.2020 / PubMed / Full text
Telomerase reverse transcriptase ameliorates lung fibrosis by protecting alveolar epithelial cells against senescence. / 31.05.2019 / PubMed / Full text
Analysis of the Association Between [i]TERC[/i] and [i]TERT[/i] Genetic Variation and Leukocyte Telomere Length and Human Lifespan-A Follow-Up Study. / 25.01.2019 / PubMed / Full text
Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. / 23.01.2019 / PubMed / Full text
Tissue iron is negatively correlated with TERC or TERT mRNA expression: A heterochronic parabiosis study in mice. / 16.12.2018 / PubMed / Full text
Cell cycle-dependent and -independent telomere shortening accompanies murine brain aging. / 20.11.2018 / PubMed / Full text
Extended proliferation of chicken- and Okinawa rail-derived fibroblasts by expression of cell cycle regulators. / 05.2019 / PubMed / Full text
The Telomerase Complex Directly Controls Hematopoietic Stem Cell Differentiation and Senescence in an Induced Pluripotent Stem Cell Model of Telomeropathy. / 2018 / PubMed / Full text
Clinical Implications of Clonal Hematopoiesis. / 08.2018 / PubMed / Full text
Contact-independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis. / 09.2018 / PubMed / Full text
Possible association of the TERT promoter polymorphisms rs2735940, rs7712562 and rs2853669 with diabetes mellitus in obese elderly Polish population: results from the national PolSenior study. / 08.2018 / PubMed / Full text
Telomerase May Paradoxically Accelerate Aging of the DNA Methylome. / 04.2018 / PubMed / Full text
Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. / 05.2018 / PubMed / Full text
GWAS of epigenetic aging rates in blood reveals a critical role for TERT. / 26.01.2018 / PubMed / Full text
Curcumin Affects Adipose Tissue-Derived Mesenchymal Stem Cell Aging Through TERT Gene Expression. / 04.2018 / PubMed / Full text
Rat adipose-derived mesenchymal stem cells aging reduction by zinc sulfate under extremely low frequency electromagnetic field exposure is associated with increased telomerase reverse transcriptase gene expression. / Spring.2017 / PubMed / Full text

CAD

Serum soluble Klotho is inversely related to coronary artery calcification assessed by intravascular ultrasound in patients with stable coronary artery disease. / 07.12.2020 / PubMed / Full text
Shear bond strengths of aged and non-aged CAD/CAM materials after different surface treatments. / 10.2020 / PubMed / Full text
Prediction of Early Postoperative Major Cardiac Events and In-Hospital Mortality in Elderly Hip Fracture Patients: The Role of Different Types of Preoperative Cardiac Abnormalities on Echocardiography Report. / 2020 / PubMed / Full text
[Polymorbidity in elderly patients needing myocardial revascularization (a review article).] / 2019 / PubMed
Fracture force of CAD/CAM resin composite crowns after in vitro aging. / 07.2020 / PubMed / Full text
Clinical performance of chairside monolithic lithium disilicate glass-ceramic CAD-CAM crowns. / 11.2019 / PubMed / Full text
Acute resveratrol supplementation in coronary artery disease: towards patient stratification. / 02.2020 / PubMed / Full text
Cellular response to moderate chromatin architectural defects promotes longevity. / 07.2019 / PubMed / Full text
Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway. / 10.06.2019 / PubMed / Full text
Altering of optical and mechanical properties in high-translucent CAD-CAM resin composites during aging. / 06.2019 / PubMed / Full text
Age-Related Improvements in Peak Cardiorespiratory Fitness among Coronary Heart Disease Patients Following Cardiac Rehabilitation. / 05.03.2019 / PubMed / Full text
Revisiting Intermittent Therapy in Metastatic Prostate Cancer: Can Less Be More in the "New World Order"? / 03.2019 / PubMed / Full text
Effect of UV aging on translucency of currently used esthetic CAD-CAM materials. / 03.2019 / PubMed / Full text
An economic analysis of salmonella detection in fresh produce, poultry, and eggs using whole genome sequencing technology in Canada. / 02.2019 / PubMed / Full text
Age, Sex, and Cardiovascular Risk Attributable to Lipoprotein Cholesterol Among Chinese Individuals with Coronary Artery Disease: A Case-Control Study. / 05.2019 / PubMed / Full text
Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease. / 05.2019 / PubMed / Full text
Age-dependent association of pulse wave velocity with coronary artery disease and myocardial aging in high-risk patients. / 04.2019 / PubMed / Full text
The Effect of Residential Aged Care Size, Ownership Model, and Multichain Affiliation on Resident Comfort and Symptom Management at the End of Life. / 03.2019 / PubMed / Full text
Cardiovascular disease in nonagenarians: Prevalence and utilization of preventive therapies. / 03.2019 / PubMed / Full text
Potential associations of testosterone/estradiol ratio, leukocyte hTERT expression and PBMC telomerase activity with aging and the presence of coronary artery disease in men. / 03.2019 / PubMed / Full text
Assessment of cardiovascular risk and preparticipation screening protocols in masters athletes: the Masters Athlete Screening Study (MASS): a cross-sectional study. / 2018 / PubMed / Full text
Comparison of marginal fit between CAD-CAM and hot-press lithium disilicate crowns. / 01.2019 / PubMed / Full text
Prognostic value of age adjusted segment involvement score as measured by coronary computed tomography: a potential marker of vascular age. / 11.2018 / PubMed / Full text
Vitamin D levels correlate with lymphocyte subsets in elderly patients with age-related diseases. / 16.05.2018 / PubMed / Full text
Effect of metabolic syndrome and aging on Ca dysfunction in coronary smooth muscle and coronary artery disease severity in Ossabaw miniature swine. / 15.07.2018 / PubMed / Full text
Definitions and clinical impact of revascularization completeness. / 10.2018 / PubMed / Full text
MicroRNA-216a induces endothelial senescence and inflammation via Smad3/IκBα pathway. / 05.2018 / PubMed / Full text
Heart Rate Fragmentation: A Symbolic Dynamical Approach. / 2017 / PubMed / Full text
Diabetes Care Disparities in Long-standing Type 1 Diabetes in Canada and the U.S.: A Cross-sectional Comparison. / 01.2018 / PubMed / Full text
The effects of aerobic and anaerobic exercises on circulating soluble-Klotho and IGF-I in young and elderly adults and in CAD patients. / 01-12.2017 / PubMed / Full text
Association between coronary artery disease severity and overactive bladder in geriatric patients. / 01.2018 / PubMed / Full text
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. / 13.10.2017 / PubMed / Full text
Association Between Mental Health Burden and Coronary Artery Disease in U.S. Women Veterans Over 45: A National Cross-Sectional Study. / 03.2018 / PubMed / Full text
Internal carotid artery dissection among younger and older patients with acute ischemic stroke. / 04.2018 / PubMed / Full text

PTEN

Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis. / 26.10.2020 / PubMed / Full text
Alterations in Mitochondrial Dynamic-related Genes in the Peripheral Blood of Alzheimer's Disease Patients. / 2020 / PubMed / Full text
Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells. / 10.08.2020 / PubMed / Full text
The precursor of PI(3,4,5)P alleviates aging by activating daf-18(Pten) and independent of daf-16. / 08.09.2020 / PubMed / Full text
Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis. / 15.09.2020 / PubMed / Full text
Downregulation of PTEN mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy. / 05.2020 / PubMed / Full text
miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1. / 12.03.2020 / PubMed / Full text
Environmental Exposures and Asthma Development: Autophagy, Mitophagy, and Cellular Senescence. / 2019 / PubMed / Full text
PTEN loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation. / 17.09.2019 / PubMed / Full text
Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. / 08.2019 / PubMed / Full text
Role of IL-37 in Cardiovascular Disease Inflammation. / 07.2019 / PubMed / Full text
Abrogation of B-Raf induced senescence by FoxM1 expression. / 27.08.2019 / PubMed / Full text
Oncogenic mutations in histologically normal endometrium: the new normal? / 10.2019 / PubMed / Full text
Double knockout of Akt2 and AMPK predisposes cardiac aging without affecting lifespan: Role of autophagy and mitophagy. / 01.07.2019 / PubMed / Full text
Single Cell Profiling Reveals PTEN Overexpression in Influenza-Specific B cells in Aging HIV-infected individuals on Anti-retroviral Therapy. / 21.02.2019 / PubMed / Full text
KIN-4/MAST kinase promotes PTEN-mediated longevity of Caenorhabditis elegans via binding through a PDZ domain. / 06.2019 / PubMed / Full text
Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF-κB activation. / 02.2019 / PubMed / Full text
Increased susceptibility of aging gastric mucosa to injury and delayed healing: Clinical implications. / 14.11.2018 / PubMed / Full text
PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. / 03.2019 / PubMed / Full text
MCL1 gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway. / 01.2019 / PubMed / Full text
Grape skin extract improves muscle function and extends lifespan of a Drosophila model of Parkinson's disease through activation of mitophagy. / 11.2018 / PubMed / Full text
Berberine ameliorates renal injury in a rat model of D-galactose-induced aging through a PTEN/Akt-dependent mechanism. / 05.2020 / PubMed / Full text
Neuronal Preconditioning Requires the Mitophagic Activity of C-terminus of HSC70-Interacting Protein. / 01.08.2018 / PubMed / Full text
Endothelial replicative senescence delayed by the inhibition of MTORC1 signaling involves MicroRNA-107. / 08.2018 / PubMed / Full text
Stanozolol administration combined with exercise leads to decreased telomerase activity possibly associated with liver aging. / 07.2018 / PubMed / Full text
Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-HDAC1-mediated regulation of autophagy. / 06.2018 / PubMed / Full text
Changes in expression of special AT-rich sequence binding protein 1 and phosphatase and tensin homologue in kidneys of diabetic rats during ageing. / 01.10.2018 / PubMed / Full text
Beyond regulation of pol III: Role of MAF1 in growth, metabolism, aging and cancer. / 04.2018 / PubMed / Full text
Neuronal PTEN deletion in adult cortical neurons triggers progressive growth of cell bodies, dendrites, and axons. / 05.2018 / PubMed / Full text
Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating PTEN. / 15.03.2018 / PubMed / Full text
miR-21 suppression prevents cardiac alterations induced by d-galactose and doxorubicin. / 02.2018 / PubMed / Full text
MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting SPRY1 via the PTEN/PI3K/AKT signaling pathway. / 05.2018 / PubMed / Full text
Global mapping of transcription factor motifs in human aging. / 2018 / PubMed / Full text
CRISPR-Cas9 Mediated Telomere Removal Leads to Mitochondrial Stress and Protein Aggregation. / 03.10.2017 / PubMed / Full text

STAT3

Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice. / 09.2020 / PubMed / Full text
Skeletal glucocorticoid signalling determines leptin resistance and obesity in aging mice. / 12.2020 / PubMed / Full text
AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF-κB/STAT3 axis-mediated positive feedback loop. / 10.2020 / PubMed / Full text
Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation. / 08.09.2020 / PubMed / Full text
Cell Death by Gallotannin Is Associated with Inhibition of the JAK/STAT Pathway in Human Colon Cancer Cells. / 2020 / PubMed / Full text
The effect of interleukin 6 deficiency on myocardial signal transduction pathways activation induced by bacterial lipopolysaccharide in young and old mice. / 09.2020 / PubMed / Full text
Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients. / 07.06.2020 / PubMed / Full text
Implication of JAK1/STAT3/SOCS3 Pathway in Aging of Cerebellum of Male Rat: Histological and Molecular study. / 01.06.2020 / PubMed / Full text
Atorvastatin-induced senescence of hepatocellular carcinoma is mediated by downregulation of hTERT through the suppression of the IL-6/STAT3 pathway. / 2020 / PubMed / Full text
Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells. / 27.01.2020 / PubMed / Full text
Persistent Activation of STAT3 Pathway in the Retina Induced Vision Impairment and Retinal Degenerative Changes in Ageing Mice. / 2019 / PubMed / Full text
Interleukin-10 induces senescence of activated hepatic stellate cells via STAT3-p53 pathway to attenuate liver fibrosis. / 02.2020 / PubMed / Full text
The proteasome activator REGγ counteracts immunoproteasome expression and autoimmunity. / 09.2019 / PubMed / Full text
Sexual dimorphism in rat thymic involution: a correlation with thymic oxidative status and inflammation. / 08.2019 / PubMed / Full text
Inflammaging: Age and Systemic, Cellular, and Nuclear Inflammatory Biology in Older Adults. / 04.10.2019 / PubMed / Full text
A novel STAT3 inhibitor, HJC0152, exerts potent antitumor activity in glioblastoma. / 2019 / PubMed / Full text
Congenital Hypothyroidism is Associated With Impairment of the Leptin Signaling Pathway in the Hypothalamus in Male Wistar Animals in Adult Life. / 05.2019 / PubMed / Full text
mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism. / 06.2019 / PubMed / Full text
[Tea polyphenols delays human glomerular mesangial cells senescence induced by high glucose via regulating STAT3/miR-126/telomere signaling pathway activation]. / 12.2018 / PubMed / Full text
STAT3 Regulates the Onset of Oxidant-induced Senescence in Lung Fibroblasts. / 07.2019 / PubMed / Full text
Deciphering Molecular and Phenotypic Changes Associated with Early Autoimmune Disease in the Aire-Deficient Mouse Model of Sjögren's Syndrome. / 17.11.2018 / PubMed / Full text
Senescent Breast Luminal Cells Promote Carcinogenesis through Interleukin-8-Dependent Activation of Stromal Fibroblasts. / 15.01.2019 / PubMed / Full text
The role of STAT3/mTOR-regulated autophagy in angiotensin II-induced senescence of human glomerular mesangial cells. / 01.2019 / PubMed / Full text
A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. / 2018 / PubMed / Full text
Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model. / 11.09.2018 / PubMed / Full text
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition. / 10.2018 / PubMed / Full text
Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text
Overexpression of Klotho Inhibits HELF Fibroblasts SASP-related Protumoral Effects on Non-small Cell Lung Cancer Cells. / 2018 / PubMed / Full text
Fibroblast senescence in the pathology of idiopathic pulmonary fibrosis. / 01.08.2018 / PubMed / Full text
Age-Associated Differences in Infection of Human Skin in the SCID Mouse Model of Varicella-Zoster Virus Pathogenesis. / 01.06.2018 / PubMed / Full text
MMP2-A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction. / 19.01.2018 / PubMed / Full text
Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia. / 01.01.2018 / PubMed / Full text
Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon. / 2017 / PubMed / Full text
Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

FEV

Prediction of Lung Function in Adolescence Using Epigenetic Aging: A Machine Learning Approach. / 09.11.2020 / PubMed / Full text
Effect of Age on the Efficacy and Safety of Once-Daily Single-Inhaler Triple Therapy Fluticasone Furoate/Umeclidinium/Vilanterol in Patients With Chronic Obstructive Pulmonary Disease: A Post Hoc Analysis of the IMPACT Trial. / 05.10.2020 / PubMed / Full text
A comprehensive analysis of factors related to lung function in older adults: Cross-sectional findings from the Canadian Longitudinal Study on Aging. / 11.2020 / PubMed / Full text
Risk factors associated with the detection of pulmonary emphysema in older asymptomatic respiratory subjects. / 09.06.2020 / PubMed / Full text
Tiotropium Respimat Efficacy and Safety in Asthma: Relationship to Age. / 09.2020 / PubMed / Full text
Current Bronchodilator Responsiveness Criteria Underestimate Asthma in Older Adults. / 08.2020 / PubMed / Full text
Physical performances show conflicting associations in aged manual workers. / 10.02.2020 / PubMed / Full text
FEV as a Standalone Spirometric Predictor and the Attributable Fraction for Death in Older Persons. / 02.2020 / PubMed / Full text
An Individualized Prediction Model for Long-term Lung Function Trajectory and Risk of COPD in the General Population. / 03.2020 / PubMed / Full text
Telomere length and lung function in a population-based cohort of children and mid-life adults. / 12.2019 / PubMed / Full text
Rate of normal lung function decline in ageing adults: a systematic review of prospective cohort studies. / 27.06.2019 / PubMed / Full text
The moderating effect of childhood disadvantage on the associations between smoking and occupational exposure and lung function; a cross sectional analysis of the UK Household Longitudinal Study (UKHLS). / 04.06.2019 / PubMed / Full text
Occupational exposure to solvents and lung function decline: A population based study. / 07.2019 / PubMed / Full text
Disease-Specific Comorbidity Clusters in COPD and Accelerated Aging. / 14.04.2019 / PubMed / Full text
The Effect of the Stretch-Shortening Cycle in the Force-Velocity Relationship and Its Association With Physical Function in Older Adults With COPD. / 2019 / PubMed / Full text
Socioeconomic status and pulmonary function, transition from childhood to adulthood: cross-sectional results from the polish part of the HAPIEE study. / 09.01.2019 / PubMed / Full text
Benefits of improved air quality on ageing lungs: impacts of genetics and obesity. / 04.2019 / PubMed / Full text
The Effects of Aging on Exhaled Nitric Oxide (FeNO) in a North African Population. / 02.2019 / PubMed / Full text
Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS). / 02.2019 / PubMed / Full text
Metastable DNA methylation sites associated with longitudinal lung function decline and aging in humans: an epigenome-wide study in the NAS and KORA cohorts. / 2018 / PubMed / Full text
Contribution of peripheral airway function to changes in FEV /FVC and RV/TLC with aging. / 01.11.2018 / PubMed / Full text
Movement behaviours are associated with lung function in middle-aged and older adults: a cross-sectional analysis of the Canadian longitudinal study on aging. / 03.07.2018 / PubMed / Full text
Relationship between pulmonary function and peripheral vascular function in older Chinese: Guangzhou biobank cohort study-CVD. / 21.05.2018 / PubMed / Full text
The role of air pollution and lung function in cognitive impairment. / 02.2018 / PubMed / Full text
Heterogeneous pattern of differences in respiratory parameters between elderly with either good or poor FEV . / 06.02.2018 / PubMed / Full text
Longitudinal assessment of lung function in extremely prematurely born children. / 03.2018 / PubMed / Full text
Older women exhibit greater airway 8-isoprostane responses to strenuous exercise compared with older men and younger controls. / 05.2018 / PubMed / Full text
The association between leisure-time physical activity and lung function in older adults: The English longitudinal study of ageing. / 01.2018 / PubMed / Full text
Spirometry reference values for an andean high-altitude population. / 01.2018 / PubMed / Full text
Consumption of fruit and vegetables might mitigate the adverse effects of ambient PM on lung function among adults. / 01.2018 / PubMed / Full text
Comparative Clinical, Physiological, and Inflammatory Characteristics of Elderly Subjects With or Without Asthma and Young Subjects With Asthma. / 12.2017 / PubMed / Full text
"Spirometric" lung age reference equations: A narrative review. / 01.2018 / PubMed / Full text
Aging and extrapulmonary effects of chronic obstructive pulmonary disease. / 2017 / PubMed / Full text

SIRT3

SIRT3 protects endothelial cells from high glucose-induced senescence and dysfunction via the p53 pathway. / 05.11.2020 / PubMed / Full text
Melatonin and Sirtuins in Buccal Epithelium: Potential Biomarkers of Aging and Age-Related Pathologies. / 30.10.2020 / PubMed / Full text
[i]SIRT3[/i] Transfection of Aged Human Bone Marrow-Derived Mesenchymal Stem Cells Improves Cell Therapy-Mediated Myocardial Repair. / 28.04.2020 / PubMed / Full text
17β-estradiol inhibits H O -induced senescence in HUVEC cells through upregulating SIRT3 expression and promoting autophagy. / 10.2020 / PubMed / Full text
CR6 interacting factor 1 deficiency induces premature senescence via SIRT3 inhibition in endothelial cells. / 04.2020 / PubMed / Full text
Mitochondrial function in skeletal myofibers is controlled by a TRF2-SIRT3 axis over lifetime. / 03.2020 / PubMed / Full text
Context-Dependent Roles for SIRT2 and SIRT3 in Tumor Development Upon Calorie Restriction or High Fat Diet. / 2019 / PubMed / Full text
The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders. / 01.2020 / PubMed / Full text
[i]Sirt3[/i] Deficiency Shortens Life Span and Impairs Cardiac Mitochondrial Function Rescued by [i]Opa1[/i] Gene Transfer. / 12.2019 / PubMed / Full text
Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro. / 08.2019 / PubMed / Full text
NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats. / 04.2019 / PubMed / Full text
Targeted Mitochondrial COQ Delivery Attenuates Antiretroviral-Drug-Induced Senescence of Neural Progenitor Cells. / 04.02.2019 / PubMed / Full text
Caffeine Protects Skin from Oxidative Stress-Induced Senescence through the Activation of Autophagy. / 2018 / PubMed / Full text
The pathophysiological importance and therapeutic potential of NAD' biosynthesis and mitochondrial sirtuin SIRT3 in age-associated diseases. / 09.2016 / PubMed
Aging-Related Overactivity of the Angiotensin/AT1 Axis Decreases Sirtuin 3 Levels in the Substantia Nigra, Which Induces Vulnerability to Oxidative Stress and Neurodegeneration. / 14.02.2020 / PubMed / Full text
6-gingerol ameliorates age-related hepatic steatosis: Association with regulating lipogenesis, fatty acid oxidation, oxidative stress and mitochondrial dysfunction. / 01.01.2019 / PubMed / Full text
Sirtuins and NAD in the Development and Treatment of Metabolic and Cardiovascular Diseases. / 14.09.2018 / PubMed / Full text
Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing SIRT1 and SIRT3 expression. / 10.2018 / PubMed / Full text
Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3. / 18.08.2018 / PubMed / Full text
Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls. / 10.2018 / PubMed / Full text
Sirtuin3 protects aged human mesenchymal stem cells against oxidative stress and enhances efficacy of cell therapy for ischaemic heart diseases. / 11.2018 / PubMed / Full text
Sirtuins in Renal Health and Disease. / 07.2018 / PubMed / Full text
Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. / 08.2018 / PubMed / Full text
Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, SIRT1, SIRT3, and VEGF in the Substantia Nigra. / 10.11.2018 / PubMed / Full text
Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas. / 08.2018 / PubMed / Full text
NAD supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency. / 20.02.2018 / PubMed / Full text
Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. / 04.2018 / PubMed / Full text
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3. / 10.2018 / PubMed / Full text
Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. / 01.2018 / PubMed / Full text
[Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell]. / 02.2017 / PubMed / Full text
Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3. / 20.10.2017 / PubMed / Full text

SOD1

SOD1, more than just an antioxidant. / 28.11.2020 / PubMed / Full text
The Exacerbation of Aging and Oxidative Stress in the Epididymis of [i]Sod1[/i] Null Mice. / 11.02.2020 / PubMed / Full text
Alterations in lipid metabolism of spinal cord linked to amyotrophic lateral sclerosis. / 12.08.2019 / PubMed / Full text
Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1 ) Mouse Model of ALS. / 10.2019 / PubMed / Full text
Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models. / 28.05.2019 / PubMed / Full text
Preventive effect of Lactobacillus plantarum KSFY02 isolated from naturally fermented yogurt from Xinjiang, China, on d-galactose-induced oxidative aging in mice. / 07.2019 / PubMed / Full text
Dynamic interplay between H-current and M-current controls motoneuron hyperexcitability in amyotrophic lateral sclerosis. / 05.04.2019 / PubMed / Full text
The M muscarinic acetylcholine receptor subtype is important for retinal neuron survival in aging mice. / 26.03.2019 / PubMed / Full text
Isoform-selective as opposed to complete depletion of fibroblast growth factor 2 (FGF-2) has no major impact on survival and gene expression in SOD1 amyotrophic lateral sclerosis mice. / 09.2019 / PubMed / Full text
Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS. / 2019 / PubMed / Full text
Neuron-targeted caveolin-1 improves neuromuscular function and extends survival in SOD1 mice. / 06.2019 / PubMed / Full text
A Combination of Intrathecal and Intramuscular Application of Human Mesenchymal Stem Cells Partly Reduces the Activation of Necroptosis in the Spinal Cord of SOD1 Rats. / 06.2019 / PubMed / Full text
Curcumin supplementation increases survival and lifespan in Drosophila under heat stress conditions. / 11.2018 / PubMed / Full text
[i]Lactobacillus plantarum[/i] CQPC11 Isolated from Sichuan Pickled Cabbages Antagonizes d-galactose-Induced Oxidation and Aging in Mice. / 20.11.2018 / PubMed / Full text
Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. / 01.2019 / PubMed / Full text
SIRT1 deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis. / 12.2018 / PubMed / Full text
Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage. / 2018 / PubMed / Full text
Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis. / 07.08.2018 / PubMed / Full text
Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles. / 04.09.2018 / PubMed / Full text
Identification of proteins potentially associated with renal aging in rats. / 14.06.2018 / PubMed / Full text
Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1 -expressing ALS mouse model. / 29.05.2018 / PubMed / Full text
Resveratrol improves in vitro maturation of oocytes in aged mice and humans. / 05.2018 / PubMed / Full text
Onjisaponin B prevents cognitive impairment in a rat model of D-galactose-induced aging. / 03.2018 / PubMed / Full text
Riluzole does not improve lifespan or motor function in three ALS mouse models. / 08.2018 / PubMed / Full text
Environment-transformable sequence-structure relationship: a general mechanism for proteotoxicity. / 04.2018 / PubMed / Full text
Time-response characteristic and potential biomarker identification of heavy metal induced toxicity in zebrafish. / 01.2018 / PubMed / Full text
Comparison of Whole Body SOD1 Knockout with Muscle-Specific SOD1 Knockout Mice Reveals a Role for Nerve Redox Signaling in Regulation of Degenerative Pathways in Skeletal Muscle. / 01.02.2018 / PubMed / Full text
Muscle Expression of SOD1 Triggers the Dismantlement of Neuromuscular Junction via PKC-Theta. / 20.04.2018 / PubMed / Full text
Circulating extracellular vesicles in the aging process: impact of aerobic exercise. / 03.2018 / PubMed / Full text
Diversity of astroglial responses across human neurodegenerative disorders and brain aging. / 09.2017 / PubMed / Full text

Aging genes 30-59

TG

CS

PC

APP

CAT

CD28

SCD

NLRP3

ACE

AMH

AR

ATM

GFAP

TH

CA3

CGA

CP

SOD2

HGS

TERT

CAD

PTEN

STAT3

FEV

SIRT3

SOD1

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