FGB

Fibrinogen beta chain precursor [Contains: Fibrinopeptide B; Fibrinogen beta chain]

Publications

[Clinical and genetic characteristics of long-livers in Moscow region].

PubMed

In Moscow region long-livers we have studied distribution of LPL, CETP, APOE, F2, F5, F7, F13, FGB, ITGA2, ITGB3, PAI-1, MTHFR, MTRR, HLA-DRB1, HLA-DQA1, HLA-DQB1 genes polymorphisms, associated with predisposition to age pathology. Long-livers are characterized by favorable course of cardiovascular diseases accompanied by certain genetic factors. We have established that genotype H-H- of LPL, allele epsilon2 of APOE, genotype CC of MTHFR (677C > T), genotype TC of ITGB3, genotype GA of FGB, HLA-DRB1*11 positively correlate with longevity.

MeSH Terms

• Aged
• Aged, 80 and over
• Alleles
• Cardiovascular Diseases
• Female
• Gene Frequency
• Genetic Markers
• Genetic Predisposition to Disease
• Genotype
• Humans
• Longevity
• Male
• Moscow
• Polymorphism, Genetic
• Prevalence
• Urban Population