Aging genes 5-9

PTEN

Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis. / 26.10.2020 / PubMed / Full text
Alterations in Mitochondrial Dynamic-related Genes in the Peripheral Blood of Alzheimer's Disease Patients. / 2020 / PubMed / Full text
Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells. / 10.08.2020 / PubMed / Full text
The precursor of PI(3,4,5)P alleviates aging by activating daf-18(Pten) and independent of daf-16. / 08.09.2020 / PubMed / Full text
Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis. / 15.09.2020 / PubMed / Full text
Downregulation of PTEN mediates bleomycin-induced premature senescence in lung cancer cells by suppressing autophagy. / 05.2020 / PubMed / Full text
miR-155 inhibits mitophagy through suppression of BAG5, a partner protein of PINK1. / 12.03.2020 / PubMed / Full text
Environmental Exposures and Asthma Development: Autophagy, Mitophagy, and Cellular Senescence. / 2019 / PubMed / Full text
PTEN loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation. / 17.09.2019 / PubMed / Full text

CCK

Senolytic agent Quercetin ameliorates intervertebral disc degeneration via the Nrf2/NF-κB axis. / 23.11.2020 / PubMed / Full text
Astragalus improve aging bone marrow mesenchymal stem cells (BMSCs) vitality and osteogenesis through VD-FGF23-Klotho axis. / 2020 / PubMed / Full text
Effects of Age on Acute Appetite-Related Responses to Whey-Protein Drinks, Including Energy Intake, Gastric Emptying, Blood Glucose, and Plasma Gut Hormone Concentrations-A Randomized Controlled Trial. / 06.04.2020 / PubMed / Full text
Lactose induced redox-dependent senescence and activated Nrf2 pathway. / 2019 / PubMed / Full text
Quercetin Suppresses the Progression of Atherosclerosis by Regulating MST1-Mediated Autophagy in ox-LDL-Induced RAW264.7 Macrophage Foam Cells. / 03.12.2019 / PubMed / Full text
LncRNA AW112010 Promotes Mitochondrial Biogenesis and Hair Cell Survival: Implications for Age-Related Hearing Loss. / 2019 / PubMed / Full text
Effects of age on feeding response: Focus on the rostral C1 neuron and its glucoregulatory proteins. / 01.2020 / PubMed / Full text
Ser-Tyr and Asn-Ala, vasorelaxing dipeptides found by comprehensive screening, reduce blood pressure via different age-dependent mechanisms. / 04.11.2019 / PubMed / Full text
Fisetin, via CKIP-1/REGγ, limits oxidized LDL-induced lipid accumulation and senescence in RAW264.7 macrophage-derived foam cells. / 15.12.2019 / PubMed / Full text

FGF21

Differential effects of sulfur amino acid-restricted and low-calorie diets on gut microbiome profile and bile acid composition in male C57BL6/J mice. / 27.10.2020 / PubMed / Full text
Relationship between physical activity and circulating fibroblast growth factor 21 in middle-aged and older adults. / 11.2020 / PubMed / Full text
Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy. / 09.2020 / PubMed / Full text
Mitochondria, immunosenescence and inflammaging: a role for mitokines? / 10.2020 / PubMed / Full text
Age-at-onset-dependent effects of sulfur amino acid restriction on markers of growth and stress in male F344 rats. / 07.2020 / PubMed / Full text
Fibroblast growth factor 21 prolongs lifespan and improves stress tolerance in the silkworm, [i]Bombyx mori[/i]. / 03.2020 / PubMed / Full text
Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice. / 13.11.2019 / PubMed / Full text
Fibroblast Growth Factor 21 Mediates the Associations between Exercise, Aging, and Glucose Regulation. / 02.2020 / PubMed / Full text
Effects of Moderate Chronic Food Restriction on the Development of Postprandial Dyslipidemia with Ageing. / 10.08.2019 / PubMed / Full text

TG

Inhibition of the alternative lengthening of telomeres pathway by subtelomeric sequences in Saccharomyces cerevisiae. / 12.2020 / PubMed / Full text
E4orf1, an Adeno-viral protein, attenuates renal lipid accumulation in high fat fed mice: A novel approach to reduce a key risk factor for chronic kidney disease. / 10.2020 / PubMed / Full text
Resistance exercise attenuates postprandial metabolic responses to a high-fat meal similarly in younger and older men. / 11.2020 / PubMed / Full text
Aging-induced aberrant RAGE/PPARα axis promotes hepatic steatosis via dysfunctional mitochondrial β oxidation. / 10.2020 / PubMed / Full text
Fenofibrate impairs liver function and structure more pronounced in old than young rats. / 27.08.2020 / PubMed / Full text
Awareness of major cardiovascular risk factors and its relationship with markers of vascular aging: Data from the Brisighella Heart Study. / 09.06.2020 / PubMed / Full text
Characterisation of the dynamic nature of lipids throughout the lifespan of genetically identical female and male Daphnia magna. / 27.03.2020 / PubMed / Full text
Effects of laboratory biotic aging on the characteristics of biochar and its water-soluble organic products. / 15.01.2020 / PubMed / Full text
Using Caenorhabditis elegans for Studying Trans- and Multi-Generational Effects of Toxicants. / 29.07.2019 / PubMed / Full text

CD34

Comparing the Effect of TGF-β Receptor Inhibition on Human Perivascular Mesenchymal Stromal Cells Derived from Endometrium, Bone Marrow and Adipose Tissues. / 01.12.2020 / PubMed / Full text
ACE2/ACE imbalance and impaired vasoreparative functions of stem/progenitor cells in aging. / 27.11.2020 / PubMed / Full text
Innovative Mind-Body Intervention Day Easy Exercise Increases Peripheral Blood CD34 Cells in Adults. / 01-12.2020 / PubMed / Full text
Human Thymic Involution and Aging in Humanized Mice. / 2020 / PubMed / Full text
Coinhibition of activated p38 MAPKα and mTORC1 potentiates stemness maintenance of HSCs from SR1-expanded human cord blood CD34 cells via inhibition of senescence. / 12.2020 / PubMed / Full text
Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype. / 09.2020 / PubMed / Full text
Mesenchymal stem cells repair bone marrow damage of aging rats and regulate autophagy and aging genes. / 08.2020 / PubMed / Full text
Immune cell extracellular vesicles and their mitochondrial content decline with ageing. / 2020 / PubMed / Full text
Young and elderly oral squamous cell carcinoma patients present similar angiogenic profile and predominance of M2 macrophages: Comparative immunohistochemical study. / 12.2019 / PubMed / Full text

ACE

Elite swimmers possess shorter telomeres than recreationally active controls. / 15.10.2020 / PubMed / Full text
Coronavirus Disease-2019 Conundrum: RAS Blockade and Geriatric-Associated Neuropsychiatric Disorders. / 2020 / PubMed / Full text
Pregnancy Protects Hyperandrogenemic Female Rats From Postmenopausal Hypertension. / 09.2020 / PubMed / Full text
Heart failure is associated with accelerated age related metabolic bone disease. / 05.06.2020 / PubMed / Full text
Management of heart failure: an Italian national survey on fellows/specialists in geriatrics. / 10.2020 / PubMed / Full text
Angiotensin-Converting Enzyme (ACE) genetic variation and longevity in Peruvian older people: a cross-sectional study. / 05.2020 / PubMed / Full text
COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection? / 30.03.2020 / PubMed / Full text
[i]A[/i]ngiotensin Converting Enzyme Inhibitors [i]C[/i]ombined with [i]E[/i]xercise for Hypertensive [i]S[/i]eniors (The ACES Trial): Study Protocol of a Randomized Controlled Trial. / 2019 / PubMed / Full text
Vascular age. / Winter.2020 / PubMed

DBP

Do baseline blood pressure and type of exercise influence level of reduction induced by training in hypertensive older adults? A meta-analysis of controlled trials. / 15.10.2020 / PubMed / Full text
Attenuated aortic blood pressure responses to metaboreflex activation in older adults with dynapenia. / 09.2020 / PubMed / Full text
The Effect of Blood Pressure on Cognitive Performance. An 8-Year Follow-Up of the Tromsø Study, Comprising People Aged 45-74 Years. / 2020 / PubMed / Full text
Low Diastolic Blood Pressure and Cognitive Decline in Korean Elderly People: The Korean Longitudinal Study on Cognitive Aging and Dementia. / 01.2020 / PubMed / Full text
Diastolic Blood Pressure Is Associated With Regional White Matter Lesion Load: The Northern Manhattan Study. / 02.2020 / PubMed / Full text
Orthostatic Hypotension and Novel Blood Pressure Associated Gene Variants in Older Adults: Data From the TILDA Study. / 15.10.2020 / PubMed / Full text
Blood pressure and hypertension prevalence among oldest-old in China for 16 year: based on CLHLS. / 09.09.2019 / PubMed / Full text
The age-related blood pressure trajectories from young-old adults to centenarians: A cohort study. / 01.12.2019 / PubMed / Full text

CAT

Training improves the handling of inhaler devices and reduces the severity of symptoms in geriatric patients suffering from chronic-obstructive pulmonary disease. / 09.10.2020 / PubMed / Full text
7-chloro-4-(phenylselanyl) quinoline co-treatment prevent oxidative stress in diabetic-like phenotype induced by hyperglycidic diet in Drosophila melanogaster. / 01.2021 / PubMed / Full text
Aging influences in the blood-brain barrier permeability and cerebral oxidative stress in sepsis. / 15.10.2020 / PubMed / Full text
2 -Deoxy - d-glucose at chronic low dose acts as a caloric restriction mimetic through a mitohormetic induction of ROS in the brain of accelerated senescence model of rat. / 09-10.2020 / PubMed / Full text
Ceftriaxone improves senile neurocognition damages induced by D-galactose in mice. / 03.2020 / PubMed / Full text
Ginsenoside Rg1 protects against d-galactose induced fatty liver disease in a mouse model via FOXO1 transcriptional factor. / 01.08.2020 / PubMed / Full text
Effects of long-term intermittent versus chronic calorie restriction on oxidative stress in a mouse cancer model. / 12.2019 / PubMed / Full text
The Toxicity of Nonaged and Aged Coated Silver Nanoparticles to Freshwater Alga Raphidocelis subcapitata. / 11.2019 / PubMed / Full text

AFM

Photocatalytic aging process of Nano-TiO coated polypropylene microplastics: Combining atomic force microscopy and infrared spectroscopy (AFM-IR) for nanoscale chemical characterization. / 15.02.2021 / PubMed / Full text
Nanoscale infrared, thermal and mechanical properties of aged microplastics revealed by an atomic force microscopy coupled with infrared spectroscopy (AFM-IR) technique. / 20.11.2020 / PubMed / Full text
Detecting zeta potential of polydimethylsiloxane (PDMS) in electrolyte solutions with atomic force microscope. / 15.10.2020 / PubMed / Full text
Recent Applications of Advanced Atomic Force Microscopy in Polymer Science: A Review. / 17.05.2020 / PubMed / Full text
Active fractions of mannoproteins derived from yeast cell wall stimulate innate and acquired immunity of adult and elderly dogs. / 03.2020 / PubMed / Full text
The Effect of Waste Engine Oil and Waste Polyethylene on UV Aging Resistance of Asphalt. / 06.03.2020 / PubMed / Full text
Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans. / 25.02.2020 / PubMed / Full text
Nanomechanical insights: Amyloid beta oligomer-induced senescent brain endothelial cells. / 01.12.2019 / PubMed / Full text

SIRT3

SIRT3 protects endothelial cells from high glucose-induced senescence and dysfunction via the p53 pathway. / 05.11.2020 / PubMed / Full text
Melatonin and Sirtuins in Buccal Epithelium: Potential Biomarkers of Aging and Age-Related Pathologies. / 30.10.2020 / PubMed / Full text
[i]SIRT3[/i] Transfection of Aged Human Bone Marrow-Derived Mesenchymal Stem Cells Improves Cell Therapy-Mediated Myocardial Repair. / 28.04.2020 / PubMed / Full text
17β-estradiol inhibits H O -induced senescence in HUVEC cells through upregulating SIRT3 expression and promoting autophagy. / 10.2020 / PubMed / Full text
CR6 interacting factor 1 deficiency induces premature senescence via SIRT3 inhibition in endothelial cells. / 04.2020 / PubMed / Full text
Mitochondrial function in skeletal myofibers is controlled by a TRF2-SIRT3 axis over lifetime. / 03.2020 / PubMed / Full text
Context-Dependent Roles for SIRT2 and SIRT3 in Tumor Development Upon Calorie Restriction or High Fat Diet. / 2019 / PubMed / Full text
The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders. / 01.2020 / PubMed / Full text

PINK1

Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in [i]C. elegans[/i]. / 09.09.2020 / PubMed / Full text
Female mice are resilient to age-related decline of substantia nigra dopamine neuron firing parameters. / 11.2020 / PubMed / Full text
Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration. / 09.2020 / PubMed / Full text
SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy. / 18.07.2020 / PubMed / Full text
Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster. / 23.09.2020 / PubMed / Full text
Compression-induced senescence of nucleus pulposus cells by promoting mitophagy activation via the PINK1/PARKIN pathway. / 05.2020 / PubMed / Full text
Doxorubicin-induced normal breast epithelial cellular aging and its related breast cancer growth through mitochondrial autophagy and oxidative stress mitigated by ginsenoside Rh2. / 07.2020 / PubMed / Full text
Mitochondrial DNA heteroplasmy rises in substantial nigra of aged PINK1 KO mice. / 22.01.2020 / PubMed / Full text

AR

Mechanisms of Androgen Receptor Agonist- and Antagonist-Mediated Cellular Senescence in Prostate Cancer. / 08.07.2020 / PubMed / Full text
Interleukin-23 Represses the Level of Cell Senescence Induced by the Androgen Receptor Antagonists Enzalutamide and Darolutamide in Castration-Resistant Prostate Cancer Cells. / 08.2020 / PubMed / Full text
A Landscape of Murine Long Non-Coding RNAs Reveals the Leading Transcriptome Alterations in Adipose Tissue during Aging. / 26.05.2020 / PubMed / Full text
Senolytic compounds control a distinct fate of androgen receptor agonist- and antagonist-induced cellular senescent LNCaP prostate cancer cells. / 2020 / PubMed / Full text
Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice. / 01.04.2020 / PubMed / Full text
A jaboticaba extract prevents prostatic damage associated with aging and high-fat diet intake. / 26.02.2020 / PubMed / Full text
Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip. / 10.2019 / PubMed / Full text

IL6

Basic immunology may lead to translational therapeutic rationale: SARS-CoV-2 and rheumatic diseases. / 09.2020 / PubMed / Full text
ATM-deficient neural precursors develop senescence phenotype with disturbances in autophagy. / 09.2020 / PubMed / Full text
The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification. / 23.06.2020 / PubMed / Full text
Impact of Influenza on Pneumococcal Vaccine Effectiveness during [i]Streptococcus pneumoniae[/i] Infection in Aged Murine Lung. / 11.06.2020 / PubMed / Full text
Patterns of multi-domain cognitive aging in participants of the Long Life Family Study. / 10.2020 / PubMed / Full text
Cholest-4,6-Dien-3-One Promote Epithelial-To-Mesenchymal Transition (EMT) in Biliary Tree Stem/Progenitor Cell Cultures In Vitro. / 15.11.2019 / PubMed / Full text
Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival. / 12.2019 / PubMed / Full text

NHS

Telomerase Activation to Reverse Immunosenescence in Elderly Patients With Acute Coronary Syndrome: Protocol for a Randomized Pilot Trial. / 23.09.2020 / PubMed / Full text
Factors associated with COVID-19-related death using OpenSAFELY. / 08.2020 / PubMed / Full text
Advanced ophthalmic nurse practitioners: the potential to improve outcomes for older people with cataracts. / 17.06.2020 / PubMed / Full text
Patient Satisfaction in the Spanish National Health Service: Partial Least Squares Structural Equation Modeling. / 04.12.2019 / PubMed / Full text
Heart failure with preserved ejection fraction (HFpEF) pathophysiology study (IDENTIFY-HF): does increased arterial stiffness associate with HFpEF, in addition to ageing and vascular effects of comorbidities? Rationale and design. / 19.11.2019 / PubMed / Full text
Challenges to concordance: theories that explain variations in patient responses. / 02.10.2019 / PubMed / Full text
Optimism is associated with exceptional longevity in 2 epidemiologic cohorts of men and women. / 10.09.2019 / PubMed / Full text

CAD

Serum soluble Klotho is inversely related to coronary artery calcification assessed by intravascular ultrasound in patients with stable coronary artery disease. / 07.12.2020 / PubMed / Full text
Shear bond strengths of aged and non-aged CAD/CAM materials after different surface treatments. / 10.2020 / PubMed / Full text
Prediction of Early Postoperative Major Cardiac Events and In-Hospital Mortality in Elderly Hip Fracture Patients: The Role of Different Types of Preoperative Cardiac Abnormalities on Echocardiography Report. / 2020 / PubMed / Full text
[Polymorbidity in elderly patients needing myocardial revascularization (a review article).] / 2019 / PubMed
Fracture force of CAD/CAM resin composite crowns after in vitro aging. / 07.2020 / PubMed / Full text
Clinical performance of chairside monolithic lithium disilicate glass-ceramic CAD-CAM crowns. / 11.2019 / PubMed / Full text
Acute resveratrol supplementation in coronary artery disease: towards patient stratification. / 02.2020 / PubMed / Full text

SI

Microarray Profiling Reveals Distinct Circulating miRNAs in Aged Male and Female Mice Subjected to Post-stroke Social Isolation. / 19.10.2020 / PubMed / Full text
Is Heart Rate a Confounding Factor for Photoplethysmography Markers? A Systematic Review. / 10.04.2020 / PubMed / Full text
Survival time after marked reduction in oral intake in terminally ill noncancer patients: A retrospective study. / 03.2020 / PubMed / Full text
Adherence to Mediterranean diet moderates the association between multimorbidity and depressive symptoms in older adults. / 05-06.2020 / PubMed / Full text
Loneliness, Social Isolation, and Objectively Measured Physical Activity in Rural-Living Older Adults. / 19.12.2019 / PubMed / Full text
The associations between social support and negative social interaction with suicidal ideation in US Chinese older adults. / 25.10.2019 / PubMed / Full text
Cell Senescence and Cerebral Small Vessel Disease in the Brains of People Aged 80 Years and Older. / 01.11.2019 / PubMed / Full text

TF

A preliminary investigation of the contribution of different tenderness factors to beef loin, tri-tip and heel tenderness. / 12.2020 / PubMed / Full text
The transcription factor ZmNAC126 accelerates leaf senescence downstream of the ethylene signalling pathway in maize. / 09.2020 / PubMed / Full text
Extensive transcriptome changes during seasonal leaf senescence in field-grown black cottonwood (Populus trichocarpa Nisqually-1). / 20.04.2020 / PubMed / Full text
Expression of Transferrin and Albumin in the Sperm-Storage Tubules of Japanese Quail and their Possible Involvement in Long-Term Sperm Storage. / 25.01.2020 / PubMed / Full text
OsWRKY5 Promotes Rice Leaf Senescence via Senescence-Associated NAC and Abscisic Acid Biosynthesis Pathway. / 09.09.2019 / PubMed / Full text
BrTCP7 Transcription Factor Is Associated with MeJA-Promoted Leaf Senescence by Activating the Expression of [i]BrOPR3[/i] and [i]BrRCCR[/i]. / 14.08.2019 / PubMed / Full text
Activation of the Transcription of [i]BrGA20ox3[/i] by a BrTCP21 Transcription Factor Is Associated with Gibberellin-Delayed Leaf Senescence in Chinese Flowering Cabbage during Storage. / 08.08.2019 / PubMed / Full text

GDF11

Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice. / 04.05.2020 / PubMed / Full text
Anti-Aging Effects of GDF11 on Skin. / 09.04.2020 / PubMed / Full text
Targeted Approach to Distinguish and Determine Absolute Levels of GDF8 and GDF11 in Mouse Serum. / 06.2020 / PubMed / Full text
Growth differentiation factor 11 impairs titanium implant healing in the femur and leads to mandibular bone loss. / 09.2020 / PubMed / Full text
Systemic GDF11 stimulates the secretion of adiponectin and induces a calorie restriction-like phenotype in aged mice. / 01.2020 / PubMed / Full text
Circulating factors in young blood as potential therapeutic agents for age-related neurodegenerative and neurovascular diseases. / 11.2019 / PubMed / Full text
Effects of Exercise Training on Growth and Differentiation Factor 11 Expression in Aged Mice. / 2019 / PubMed / Full text

SDS

Semiautomatic morphometric analysis of skeletal muscle obtained by needle biopsy in older adults. / 12.2020 / PubMed / Full text
Effects of late-onset dietary intake of salidroside on insulin/insulin-like growth factor-1 (IGF-1) signaling pathway of the annual fish Nothobranchius guentheri. / 17.08.2020 / PubMed / Full text
Quantification of Insoluble Protein Aggregation in Caenorhabditis elegans during Aging with a Novel Data-Independent Acquisition Workflow. / 07.08.2020 / PubMed / Full text
Skeletal Muscle Myofibrillar Protein Abundance Is Higher in Resistance-Trained Men, and Aging in the Absence of Training May Have an Opposite Effect. / 10.01.2020 / PubMed / Full text
Characterization, evaluation of nutritional parameters of Radix isatidis protein and its antioxidant activity in D-galactose induced ageing mice. / 06.11.2019 / PubMed / Full text
[Effects of silver nanoparticles on pupation, eclosion, life span, apoptosis and protein expression in Drosophila melanogaster]. / 10.2019 / PubMed / Full text
Does an Age-Specific Treatment Program Augment the Efficacy of a Cognitive-Behavioral Weight Loss Program in Adolescence and Young Adulthood? Results from a Controlled Study. / 02.09.2019 / PubMed / Full text

DDT

Prognostic Value of a Test of Central Auditory Function in Conversion from Mild Cognitive Impairment to Dementia. / 2020 / PubMed / Full text
Uptake kinetics of four hydrophobic organic pollutants in the earthworm Eisenia andrei in aged laboratory-contaminated natural soils. / 01.04.2020 / PubMed / Full text
Adult exposure to insecticides causes persistent behavioral and neurochemical alterations in zebrafish. / 03-04.2020 / PubMed / Full text
Second generation effects of larval metal pollutant exposure on reproduction, longevity and insecticide tolerance in the major malaria vector Anopheles arabiensis (Diptera: Culicidae). / 07.01.2020 / PubMed / Full text
Protective effect of Pedro-Ximénez must against p,p'-DDE-induced liver damages in aged Mus spretus mice. / 02.2020 / PubMed / Full text
Low-dose endosulfan inhibits proliferation and induces senescence and pro-inflammatory cytokine production in human lymphocytes, preferentially impacting cytotoxic cells. / 12.2019 / PubMed / Full text

GDF15

Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging. / 31.10.2020 / PubMed / Full text
Growth differentiation factor 15 protects against the aging-mediated systemic inflammatory response in humans and mice. / 08.2020 / PubMed / Full text
Analysis of Epigenetic Age Predictors in Pain-Related Conditions. / 2020 / PubMed / Full text
GDF15 Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness. / 2020 / PubMed / Full text
GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis. / 01.10.2019 / PubMed / Full text
Senescence-associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15. / 12.2019 / PubMed / Full text

CD44

Hyaluronan goes to great length. / 17.07.2020 / PubMed / Full text
Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties. / 12.05.2020 / PubMed / Full text
Maturity-dependent cartilage cell plasticity and sensitivity to external perturbation. / 06.2020 / PubMed / Full text
Aged Mice Exhibit Severe Exacerbations of Dry Eye Disease with an Amplified Memory Th17 Cell Response. / 07.2020 / PubMed / Full text
Chronic circadian misalignment accelerates immune senescence and abbreviates lifespan in mice. / 13.02.2020 / PubMed / Full text
Defective induction of the proteasome associated with T-cell receptor signaling underlies T-cell senescence. / 12.2019 / PubMed / Full text

APC

Differences between blacks and whites in well-being, beliefs, emotional states, behaviors and survival, 1978-2014. / 2020 / PubMed / Full text
Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion During Aging. / 07.08.2020 / PubMed / Full text
Burden of musculoskeletal disorders in Iran during 1990-2017: estimates from the Global Burden of Disease Study 2017. / 10.07.2020 / PubMed / Full text
Fall-related mortality trends in older Japanese adults aged ≥65 years: a nationwide observational study. / 11.12.2019 / PubMed / Full text
Stroke Mortality Rates and Trends in Romania, 1994-2017. / 12.2019 / PubMed / Full text
A new approach to quantifying the EEG during walking: Initial evidence of gait related potentials and their changes with aging and dual tasking. / 15.10.2019 / PubMed / Full text

CCR2

Hip Fracture Leads to Transitory Immune Imprint in Older Patients. / 2020 / PubMed / Full text
The CC-chemokine receptor 2 is involved in the control of ovarian folliculogenesis and fertility lifespan in mice. / 09.2020 / PubMed / Full text
Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity. / 08.2020 / PubMed / Full text
Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction. / 26.03.2020 / PubMed / Full text
Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by CCR2. / 02.2020 / PubMed / Full text
Klotho-mediated targeting of CCL2 suppresses the induction of colorectal cancer progression by stromal cell senescent microenvironments. / 11.2019 / PubMed / Full text

PCNA

Impairment of Pol β-related DNA Base-excision Repair Leads to Ovarian Aging in Mice. / 20.11.2020 / PubMed / Full text
[Heat shock protein 90 (HSP90) in age-dependent changes in the number of fibroblasts in human skin.] / 2020 / PubMed
A Higher Frequency Administration of the Nontoxic Cycloartane-Type Triterpene Argentatin A Improved Its Anti-Tumor Activity. / 14.04.2020 / PubMed / Full text
[Mechanosensitive protein of Hippo regulatory pathway - transcription coactivator with PZD-binding motif (TAZ) in human skin during aging.] / 2019 / PubMed
[Mechanosensitive Yes-associated protein in human skin during aging.] / 2019 / PubMed
[Role of mechanosensitive protein Piezo1 in human age-dependent changes in the number of fibroblasts and blood vessels in human skin.] / 2019 / PubMed

EGF

Acute, exercise-induced alterations in cytokines and chemokines in the blood distinguish physically active and sedentary aging. / 08.12.2020 / PubMed / Full text
Proinflammation, profibrosis, and arterial aging. / 09.2020 / PubMed / Full text
Hinokitiol induces cell death and inhibits epidermal growth factor-induced cell migration and signaling pathways in human cervical adenocarcinoma. / 09.2020 / PubMed / Full text
Activation of epidermal growth factor receptor signaling mediates cellular senescence induced by certain pro-inflammatory cytokines. / 05.2020 / PubMed / Full text
Insulin Signaling in Intestinal Stem and Progenitor Cells as an Important Determinant of Physiological and Metabolic Traits in [i]Drosophila[/i]. / 26.03.2020 / PubMed / Full text
Different cellular properties and loss of nuclear signalling of porcine epidermal growth factor receptor with aging. / 01.05.2020 / PubMed / Full text

FOXO3

The DNA methylation of FOXO3 and TP53 as a blood biomarker of late-onset asthma. / 09.12.2020 / PubMed / Full text
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16 increase. / 11.2020 / PubMed / Full text
Astaxanthin as a Putative Geroprotector: Molecular Basis and Focus on Brain Aging. / 05.07.2020 / PubMed / Full text
Inflamma-miR-21 Negatively Regulates Myogenesis during Ageing. / 23.04.2020 / PubMed / Full text
Variable DNA methylation of aging-related genes is associated with male COPD. / 04.11.2019 / PubMed / Full text
A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster. / 08.2019 / PubMed / Full text

ABR

[Hidden hearing loss and early identification]. / 07.2020 / PubMed / Full text
Aging But Not Age-Related Hearing Loss Dominates the Decrease of Parvalbumin Immunoreactivity in the Primary Auditory Cortex of Mice. / 05-06.2020 / PubMed / Full text
Hearing loss through apoptosis of the spiral ganglion neurons in apolipoprotein E knockout mice fed with a western diet. / 12.03.2020 / PubMed / Full text
Effects of enriched endogenous omega-3 fatty acids on age-related hearing loss in mice. / 26.11.2019 / PubMed / Full text
Hearing impairment and associated morphological changes in pituitary adenylate cyclase activating polypeptide (PACAP)-deficient mice. / 10.10.2019 / PubMed / Full text
Global nurse/midwife workforce and reproductive health through social ecology lens. / 09.2019 / PubMed / Full text

NGF

Dietary fish hydrolysate supplementation containing n-3 LC-PUFAs and peptides prevents short-term memory and stress response deficits in aged mice. / 23.09.2020 / PubMed / Full text
Imbalance of nerve growth factor metabolism in aging women with overactive bladder syndrome. / 01.09.2020 / PubMed / Full text
Parity Attenuates Intraepithelial Corneal Sensory Nerve Loss in Female Mice. / 21.07.2020 / PubMed / Full text
Cholinergic System and NGF Receptors: Insights from the Brain of the Short-Lived Fish [i]Nothobranchius furzeri[/i]. / 20.06.2020 / PubMed / Full text
Retrograde axonal transport of BDNF and proNGF diminishes with age in basal forebrain cholinergic neurons. / 12.2019 / PubMed / Full text
C-SH2 point mutation converts p85β regulatory subunit of phosphoinositide 3-kinase to an anti-aging gene. / 03.09.2019 / PubMed / Full text

CD38

Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction. / 02.11.2020 / PubMed / Full text
TNFRSF12A and CD38 Contribute to a Vicious Circle for Chronic Obstructive Pulmonary Disease by Engaging Senescence Pathways. / 2020 / PubMed / Full text
Aging alters acetylation status in skeletal and cardiac muscles. / 06.2020 / PubMed / Full text
CD38 in Neurodegeneration and Neuroinflammation. / 18.02.2020 / PubMed / Full text
CD38, a Receptor with Multifunctional Activities: From Modulatory Functions on Regulatory Cell Subsets and Extracellular Vesicles, to a Target for Therapeutic Strategies. / 27.11.2019 / PubMed / Full text
CD38 Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD /Sirt1 Signaling Pathway. / 2019 / PubMed / Full text

LMNA

Metformin alters peripheral blood mononuclear cells (PBMC) senescence biomarkers gene expression in type 2 diabetic patients. / 01.2021 / PubMed / Full text
Protein structural and mechanistic basis of progeroid laminopathies. / 16.08.2020 / PubMed / Full text
Progerin Expression Induces Inflammation, Oxidative Stress and Senescence in Human Coronary Endothelial Cells. / 12.05.2020 / PubMed / Full text
The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes. / 04.2020 / PubMed / Full text
Pharmacotherapy to gene editing: potential therapeutic approaches for Hutchinson-Gilford progeria syndrome. / 04.2020 / PubMed / Full text
Long term breeding of the Lmna G609G progeric mouse: Characterization of homozygous and heterozygous models. / 02.2020 / PubMed / Full text

IVD

MicroRNAs in Intervertebral Disc Degeneration, Apoptosis, Inflammation, and Mechanobiology. / 20.05.2020 / PubMed / Full text
A step-by-step protocol for isolation of murine nucleus pulposus cells. / 12.2019 / PubMed / Full text
Caspase-3 knockout inhibits intervertebral disc degeneration related to injury but accelerates degeneration related to aging. / 18.12.2019 / PubMed / Full text
Finite element and deformation analyses predict pattern of bone failure in loaded zebrafish spines. / 29.11.2019 / PubMed / Full text
Improvement in determining the risk of damage to the human lumbar functional spinal unit considering age, height, weight and sex using a combination of FEM and RSM. / 02.2020 / PubMed / Full text
In vivo contrast-enhanced microCT for the monitoring of mouse thoracic, lumbar, and coccygeal intervertebral discs. / 06.2019 / PubMed / Full text

H2AX

Evaluation of GammaH2AX in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer's Disease in the AIBL Study of Ageing. / 06.08.2020 / PubMed / Full text
Cisplatin-induced peripheral neuropathy is associated to neuronal senescence-like response. / 29.06.2020 / PubMed / Full text
Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites. / 06.04.2020 / PubMed / Full text
Do BRCA1 and BRCA2 gene mutation carriers have a reduced ovarian reserve? Protocol for a prospective observational study. / 25.11.2019 / PubMed / Full text
Slower rates of accumulation of DNA damage in leukocytes correlate with longer lifespans across several species of birds and mammals. / 15.11.2019 / PubMed / Full text
Phosphoproteomic analysis reveals plant DNA damage signalling pathways with a functional role for histone H2AX phosphorylation in plant growth under genotoxic stress. / 12.2019 / PubMed / Full text