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Редактирование:
Aging genes 40-49
(раздел)
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==FGF21== * {{medline-title |title=Differential effects of sulfur amino acid-restricted and low-calorie diets on gut microbiome profile and bile acid composition in male C57BL6/J mice. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33106871 |full-text-url=https://sci-hub.do/10.1093/gerona/glaa270 }} * {{medline-title |title=Disease-specific plasma levels of mitokines [[FGF21]], [[GDF15]], and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging. |date=31.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33131010 |full-text-url=https://sci-hub.do/10.1007/s11357-020-00287-w }} * {{medline-title |title=Alignment of Alzheimer's disease amyloid β-peptide and klotho. |date=11-12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32999998 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521834 }} * {{medline-title |title=Relationship between physical activity and circulating fibroblast growth factor 21 in middle-aged and older adults. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32911033 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111081 }} * {{medline-title |title=Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32863214 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365984 }} * {{medline-title |title=Mitochondria, immunosenescence and inflammaging: a role for mitokines? |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32757036 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666292 }} * {{medline-title |title=Age-at-onset-dependent effects of sulfur amino acid restriction on markers of growth and stress in male F344 rats. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32573078 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426777 }} * {{medline-title |title=Fibroblast growth factor 21 prolongs lifespan and improves stress tolerance in the silkworm, [i]Bombyx mori[/i]. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32309367 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154471 }} * {{medline-title |title=Myokines as biomarkers of frailty and cardiovascular disease risk in females. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32017952 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110859 }} * {{medline-title |title=Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice. |date=13.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31723038 |full-text-url=https://sci-hub.do/10.1126/scitranslmed.aau4760 }} * {{medline-title |title=Fibroblast Growth Factor 21 Mediates the Associations between Exercise, Aging, and Glucose Regulation. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31490857 |full-text-url=https://sci-hub.do/10.1249/MSS.0000000000002150 }} * {{medline-title |title=Effects of Moderate Chronic Food Restriction on the Development of Postprandial Dyslipidemia with Ageing. |date=10.08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31405194 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723802 }} * {{medline-title |title=Inhibition of the Fission Machinery Mitigates [[OPA1]] Impairment in Adult Skeletal Muscles. |date=15.06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208084 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627087 }} * {{medline-title |title=Higher serum levels of fibroblast growth factor 21 in old patients with cachexia. |date=07-08.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30933730 |full-text-url=https://sci-hub.do/10.1016/j.nut.2018.11.004 }} * {{medline-title |title=Impact of aging and caloric restriction on fibroblast growth factor 21 signaling in rat white adipose tissue. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30620889 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.001 }} * {{medline-title |title=Kotho and aging. |date=09.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557478 }} * {{medline-title |title=The Klotho proteins in health and disease. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427 |full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3 }} * {{medline-title |title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357 |full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004 }} * {{medline-title |title=Aging is associated with increased [[FGF21]] levels but unaltered [[FGF21]] responsiveness in adipose tissue. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30043445 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156525 }} * {{medline-title |title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896 }} * {{medline-title |title=Human Aging and Longevity Are Characterized by High Levels of Mitokines. |date=23.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955888 |full-text-url=https://sci-hub.do/10.1093/gerona/gly153 }} * {{medline-title |title=[Fibroblast growth factor-21 as a marker of premature aging in young and middled-aged men with type 2 diabetes]. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29634140 }} * {{medline-title |title=Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through [[SIRT1]]. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29118911 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666058 }} * {{medline-title |title=Integrated stress response stimulates [[FGF21]] expression: Systemic enhancer of longevity. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28844867 |full-text-url=https://sci-hub.do/10.1016/j.cellsig.2017.08.009 }} * {{medline-title |title=Fibroblast growth factor 21: a regulator of metabolic disease and health span. |date=01.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28559437 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625087 }} * {{medline-title |title=Age-Associated Loss of [[OPA1]] in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence. |date=06.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28552492 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462533 }} * {{medline-title |title=Regulation of longevity by [[FGF21]]: Interaction between energy metabolism and stress responses. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28552719 |full-text-url=https://sci-hub.do/10.1016/j.arr.2017.05.004 }} * {{medline-title |title=[[FGF21]] activates AMPK signaling: impact on metabolic regulation and the aging process. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27678528 |full-text-url=https://sci-hub.do/10.1007/s00109-016-1477-1 }} * {{medline-title |title=Methionine restriction improves renal insulin signalling in aged kidneys. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27453066 |full-text-url=https://sci-hub.do/10.1016/j.mad.2016.07.003 }} * {{medline-title |title=[[FGF21]] represses cerebrovascular aging via improving mitochondrial biogenesis and inhibiting p53 signaling pathway in an AMPK-dependent manner. |date=15.08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27364911 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2016.06.020 }} * {{medline-title |title=Role of mitochondrial function in cell death and body metabolism. |date=01.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27100503 |full-text-url=https://sci-hub.do/10.2741/4453 }} * {{medline-title |title=Prolongevity hormone [[FGF21]] protects against immune senescence by delaying age-related thymic involution. |date=26.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26755598 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743827 }} * {{medline-title |title=Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 ([[FGF21]]) in aging mice. |date=15.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26697751 |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.12.045 }} * {{medline-title |title=Effect of mitochondrial stress on systemic metabolism. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26100439 |full-text-url=https://sci-hub.do/10.1111/nyas.12822 }} * {{medline-title |title=Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity. |date=03.08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26121750 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563739 }} * {{medline-title |title=Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individuals. |date=01.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26042208 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450097 }} * {{medline-title |title=A preliminary candidate approach identifies the combination of chemerin, fetuin-A, and fibroblast growth factors 19 and 21 as a potential biomarker panel of successful aging. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25911468 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409588 }} * {{medline-title |title=Fibroblast growth factor 21 protects mouse brain against D-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25871519 |full-text-url=https://sci-hub.do/10.1016/j.pbb.2015.03.020 }} * {{medline-title |title=Cardiorespiratory fitness and visceral fat are key determinants of serum fibroblast growth factor 21 concentration in Japanese men. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25013999 |full-text-url=https://sci-hub.do/10.1210/jc.2014-1877 }} * {{medline-title |title=Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24935677 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331744 }} * {{medline-title |title=High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: involvement of peroxisome proliferator-activated receptor γ signaling. |date=11.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23897951 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806592 }}
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