Aging genes 60-99

CRP

Omega-3 supplementation improves isometric strength but not muscle anabolic and catabolic signaling in response to resistance exercise in healthy older adults. / 07.12.2020 / PubMed / Full text
Circulating angiopoietin-like protein 2 levels and arterial stiffness in patients receiving maintenance hemodialysis: A cross-sectional study. / 02.11.2020 / PubMed / Full text
Cardiovascular rehabilitation in patients aged 70-year-old or older: benefits on functional capacity, physical activity and metabolic profile in younger [i]vs[/i]. older patients. / 28.09.2020 / PubMed / Full text
rRT-PCR Results of a Covid-19 Diagnosed Geriatric Patient. / 17.10.2020 / PubMed / Full text
The Association of Aging Biomarkers, Interstitial Lung Abnormalities, and Mortality. / 20.10.2020 / PubMed / Full text
A Novel Fortified Dairy Product and Sarcopenia Measures in Sarcopenic Older Adults: A Double-Blind Randomized Controlled Trial. / 13.10.2020 / PubMed / Full text
Age-Related Colonic Mucosal Microbiome Community Shifts in Monkeys. / 06.10.2020 / PubMed / Full text
The relationship between frailty and serum alpha klotho levels in geriatric patients. / 08.08.2020 / PubMed / Full text
ZMPSTE24 Is Associated with Elevated Inflammation and Progerin mRNA. / 28.08.2020 / PubMed / Full text
Cultural and life style practices associated with low inflammatory physiology in Japanese adults. / 11.2020 / PubMed / Full text
Moderate- to high intensity aerobic and resistance exercise reduces peripheral blood regulatory cell populations in older adults with rheumatoid arthritis. / 2020 / PubMed / Full text
PTSD and the klotho longevity gene: Evaluation of longitudinal effects on inflammation via DNA methylation. / 07.2020 / PubMed / Full text
Bereavement is associated with reduced systemic inflammation: C-reactive protein before and after widowhood. / 08.2020 / PubMed / Full text
The Impact of Age on the Prevalence of Sarcopenic Obesity in Bariatric Surgery Candidates. / 06.2020 / PubMed / Full text
Intake of dietary advanced glycation end products influences inflammatory markers, immune phenotypes, and antiradical capacity of healthy elderly in a little-studied population. / 02.2020 / PubMed / Full text
Intentional Switching Between Bimanual Coordination Patterns in Older Adults: Is It Mediated by Inhibition Processes? / 2020 / PubMed / Full text
Shorter Telomere Length in Peripheral Blood Leukocytes Is Associated with Post-Traumatic Chronic Osteomyelitis. / 11.2020 / PubMed / Full text
Risk Factors of Progression to Frailty: Findings from the Singapore Longitudinal Ageing Study. / 2020 / PubMed / Full text
Physical Function and Strength in Relation to Inflammation in Older Adults with Obesity and Increased Cardiometabolic Risk. / 2019 / PubMed / Full text
Key diagnostic characteristics of fever of unknown origin in Japanese patients: a prospective multicentre study. / 19.11.2019 / PubMed / Full text
Decrease in Serum Vitamin D Level of Older Patients with Fatigue. / 20.10.2019 / PubMed / Full text
The Association between Frailty Indicators and Blood-Based Biomarkers in Early-Old Community Dwellers of Thailand. / 17.09.2019 / PubMed / Full text
Associations of C-reactive protein and homocysteine concentrations with the impairment of intrinsic capacity domains over a 5-year follow-up among community-dwelling older adults at risk of cognitive decline (MAPT Study). / 11.2019 / PubMed / Full text
Longitudinal analysis of loneliness and inflammation at older ages: English longitudinal study of ageing. / 12.2019 / PubMed / Full text
The cortisol burden in elderly subjects with metabolic syndrome and its association with low-grade inflammation. / 07.2020 / PubMed / Full text
Recurrent circadian fasting (RCF) improves blood pressure, biomarkers of cardiometabolic risk and regulates inflammation in men. / 19.08.2019 / PubMed / Full text
Characteristics of patients with rheumatoid arthritis undergoing primary total joint replacement: A 14-year trend analysis (2004-2017). / 07.2020 / PubMed / Full text
Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells. / 03.08.2019 / PubMed / Full text
Inflammatory markers and bone health in postmenopausal women: a cross-sectional overview. / 2019 / PubMed / Full text
Frailty is associated with elevated CRP trajectories and higher numbers of neutrophils and monocytes. / 01.10.2019 / PubMed / Full text
Relationship between circulating microparticles and hypertension and other cardiac disease biomarkers in the elderly. / 09.07.2019 / PubMed / Full text
The Impact of Prophylactic Lacosamide on LPS-Induced Neuroinflammation in Aged Rats. / 10.2019 / PubMed / Full text
Impaired sleep quality is associated with concurrent elevations in inflammatory markers: are post-menopausal women at greater risk? / 08.07.2019 / PubMed / Full text
A novel biomarker of cardiometabolic pathology in schizophrenia? / 10.2019 / PubMed / Full text
Differential clusters of modifiable risk factors for impaired fasting glucose [i]versus[/i] impaired glucose tolerance in adults 50 years of age and older. / 2019 / PubMed / Full text
[Association of plasma albumin and hypersensitive C-reactive protein with 5-year all-cause mortality among Chinese older adults aged 65 and older from 8 longevity areas in China]. / 06.06.2019 / PubMed / Full text
[Estimated glomerular filtration rate and post-hospital mortality after discharge from an acute care for the elderly unit]. / 09-10.2019 / PubMed / Full text
Racial differences in inflammation and outcomes of aging among kidney transplant candidates. / 17.05.2019 / PubMed / Full text
Is anger, but not sadness, associated with chronic inflammation and illness in older adulthood? / 05.2019 / PubMed / Full text
Elevated levels of CRP and IL-8 are related to reduce survival time: 1-year follow-up measurements of different analytes in frail elderly nursing home residents. / 09.2019 / PubMed / Full text
Antiphospholipid Antibodies: Cognitive and Motor Decline, Neuroimaging and Neuropathology. / 2019 / PubMed / Full text
Inflammatory signatures in older persons with physical frailty and sarcopenia: The frailty "cytokinome" at its core. / 15.07.2019 / PubMed / Full text
High Body Mass Index is Associated with Elevated Blood Levels of Progerin mRNA. / 23.04.2019 / PubMed / Full text
Combined exercise training improves blood pressure and antioxidant capacity in elderly individuals with hypertension. / 20.01.2019 / PubMed / Full text
Inflammatory markers and occurrence of falls: Bambuí Cohort Study of Aging. / 01.04.2019 / PubMed / Full text
Inflammation and quality of life in later life: findings from the health, well-being and aging study (SABE). / 06.02.2019 / PubMed / Full text
Gender-specific association of body composition with inflammatory and adipose-related markers in healthy elderly Europeans from the NU-AGE study. / 09.2019 / PubMed / Full text
Associations of systemic inflammation with frontotemporal functional network connectivity and out-degree social-network size in community-dwelling older adults. / 07.2019 / PubMed / Full text
Muscle function and age are associated with loss of bone mineral density in Duchenne muscular dystrophy. / 04.2019 / PubMed / Full text
Cost-effectiveness of Canakinumab for Prevention of Recurrent Cardiovascular Events. / 01.02.2019 / PubMed / Full text
Resistance training performed with single-set is sufficient to reduce cardiovascular risk factors in untrained older women: The randomized clinical trial. Active Aging Longitudinal Study. / 03-04.2019 / PubMed / Full text
Comparison of body condition score and other minimally invasive biomarkers between dogs with gastric carcinoma and dogs with chronic gastritis. / 15.01.2019 / PubMed / Full text
Intracranial Vessel Wall Lesions on 7T MRI (Magnetic Resonance Imaging). / 01.2019 / PubMed / Full text
Aging-associated latent herpes viral infection in normal Japanese individuals and patients with Werner syndrome. / 11.2018 / PubMed / Full text
Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing. / 20.12.2018 / PubMed / Full text
Role of Exercise in Vascular Function and Inflammatory Profile in Age-Related Obesity. / 2018 / PubMed / Full text
White blood cell counts in a geriatric hospitalized population: A poor diagnostic marker of infection. / 12.2018 / PubMed / Full text
Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia. / 15.11.2018 / PubMed / Full text
Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults. / 09.2018 / PubMed / Full text
Inflammatory mechanisms underlying the effects of everyday discrimination on age-related memory decline. / 01.2019 / PubMed / Full text
Hepatocyte growth factor is a potential biomarker for osteoproliferation and osteoporosis in ankylosing spondylitis. / 02.2019 / PubMed / Full text
Effects of 8-week kettlebell training on body composition, muscle strength, pulmonary function, and chronic low-grade inflammation in elderly women with sarcopenia. / 02.10.2018 / PubMed / Full text
Socioeconomic Status and Biological Risks for Health and Illness Across the Life Course. / 14.02.2020 / PubMed / Full text
Combined influence of depressive symptoms and systemic inflammation on all-cause and cardiovascular mortality: evidence for differential effects by gender in the English Longitudinal Study of Ageing. / 07.2019 / PubMed / Full text
A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup. / 12.2018 / PubMed / Full text
Systemic Inflammation Mediates Age-Related Cognitive Deficits. / 2018 / PubMed / Full text
Partnership trajectories and cardiovascular health in late life of older adults in England and Germany. / 12.2018 / PubMed / Full text
Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice. / 15.10.2018 / PubMed / Full text
Effect of resistance training on inflammatory markers of older adults: A meta-analysis. / 01.10.2018 / PubMed / Full text
Markers of Inflammation and Monoamine Metabolism Indicate Accelerated Aging in Bipolar Disorder. / 2018 / PubMed / Full text
Accelerated vascular aging and persistent cognitive impairment in older female breast cancer survivors. / 06.2018 / PubMed / Full text
Evidence-based nutritional and pharmacological interventions targeting chronic low-grade inflammation in middle-age and older adults: A systematic review and meta-analysis. / 09.2018 / PubMed / Full text
Psychosocial stress and inflammation driving tryptophan breakdown in children and adolescents: A cross-sectional analysis of two cohorts. / 08.2018 / PubMed / Full text
Disparate Habitual Physical Activity and Dietary Intake Profiles of Elderly Men with Low and Elevated Systemic Inflammation. / 04.05.2018 / PubMed / Full text
C-Reactive Protein as a Therapeutic Target in Age-Related Macular Degeneration. / 2018 / PubMed / Full text
The association of mid-to late-life systemic inflammation with white matter structure in older adults: The Atherosclerosis Risk in Communities Study. / 08.2018 / PubMed / Full text
Relationships Among C-Reactive Protein, Alanine Aminotransferase, and Metabolic Syndrome in Apparently Healthy Chinese Subjects. / 06.2018 / PubMed / Full text
Reduction of Premature Aging Markers After Gastric Bypass Surgery in Morbidly Obese Patients. / 09.2018 / PubMed / Full text
C-Reactive Protein Impairs Dendritic Cell Development, Maturation, and Function: Implications for Peripheral Tolerance. / 2018 / PubMed / Full text
Proximity of Cytomegalovirus-Specific CD8 T Cells to Replicative Senescence in Human Immunodeficiency Virus-Infected Individuals. / 2018 / PubMed / Full text
Association of 10-Year C-Reactive Protein Trajectories With Markers of Healthy Aging: Findings From the English Longitudinal Study of Aging. / 16.01.2019 / PubMed / Full text
Metabolic Clusters and Outcomes in Older Adults: The Cardiovascular Health Study. / 02.2018 / PubMed / Full text
Low-grade systemic inflammation is associated with functional disability in elderly people affected by dementia. / 02.2018 / PubMed / Full text
Systemic inflammation and functional capacity in elderly heart failure patients. / 04.2018 / PubMed / Full text
Oxidative stress predicts cognitive decline with aging in healthy adults: an observational study. / 16.01.2018 / PubMed / Full text
Systemic inflammation as a predictor of brain aging: Contributions of physical activity, metabolic risk, and genetic risk. / 15.05.2018 / PubMed / Full text
The association between C-reactive protein, Interleukin-6 and depression among older adults in the community: A systematic review and meta-analysis. / 02.2018 / PubMed / Full text
TNF-α antagonism with etanercept enhances penile NOS expression, cavernosal reactivity, and testosterone levels in aged rats. / 02.2018 / PubMed / Full text
Phase angle is related with inflammatory and oxidative stress biomarkers in older women. / 02.2018 / PubMed / Full text
Elderly Patients Exhibit Stronger Inflammatory Responses during Gout Attacks. / 12.2017 / PubMed / Full text
Differential Relationships among Circulating Inflammatory and Immune Activation Biomediators and Impact of Aging and Human Immunodeficiency Virus Infection in a Cohort of Injection Drug Users. / 2017 / PubMed / Full text
High-sensitivity C-reactive protein and cognitive decline: the English Longitudinal Study of Ageing. / 06.2018 / PubMed / Full text
Handgrip strength shows no improvements in geriatric patients with persistent inflammation during hospitalization. / 01.12.2017 / PubMed / Full text
Vascular, inflammatory, and metabolic factors associated with cognition in aging persons with chronic epilepsy. / 11.2017 / PubMed / Full text
Genetic and environmental influences on stability and change in baseline levels of C-reactive protein: A longitudinal twin study. / 10.2017 / PubMed / Full text
Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients. / 2017 / PubMed / Full text
Association of pre-chemotherapy peripheral blood pro-inflammatory and coagulation factors with reduced relative dose intensity in women with breast cancer. / 29.08.2017 / PubMed / Full text
Factors affecting lifespan following below-knee amputation in diabetic patients. / 10.2017 / PubMed / Full text
Serum C-Reactive Protein and Congestive Heart Failure as Significant Predictors of Herpes Zoster Vaccine Response in Elderly Nursing Home Residents. / 15.07.2017 / PubMed / Full text

RPE

Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time. / 08.12.2020 / PubMed / Full text
Relationship between Oxygen Uptake, Heart Rate, and Perceived Effort in an Aquatic Incremental Test in Older Women. / 11.11.2020 / PubMed / Full text
Photoreceptor Degeneration in Homozygous Male Per2 Mice During Aging. / 02.11.2020 / PubMed / Full text
An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into RPE Stress Associated with Retinopathy. / 11.09.2020 / PubMed / Full text
Short-Term Effect of Self-Selected Training Intensity on Ambulatory Blood Pressure in Hypertensive Older Women: A Randomized Controlled Trial. / 2020 / PubMed / Full text
Correlation between brain volume and retinal photoreceptor outer segment volume in normal aging and neurodegenerative diseases. / 2020 / PubMed / Full text
Oxidative stress in the retina and retinal pigment epithelium (RPE): Role of aging, and DJ-1. / 17.07.2020 / PubMed / Full text
Direct-Coupled Electroretinogram (DC-ERG) for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium. / 14.07.2020 / PubMed / Full text
High-density lipoproteins are a potential therapeutic target for age-related macular degeneration. / 25.09.2020 / PubMed / Full text
MTOR-initiated metabolic switch and degeneration in the retinal pigment epithelium. / 09.2020 / PubMed / Full text
[i]Lactobacillus paracasei[/i] KW3110 Suppresses Inflammatory Stress-Induced Premature Cellular Senescence of Human Retinal Pigment Epithelium Cells and Reduces Ocular Disorders in Healthy Humans. / 18.07.2020 / PubMed / Full text
Retinal pigment epithelium transcriptome analysis in chronic smoking reveals a suppressed innate immune response and activation of differentiation pathways. / 20.08.2020 / PubMed / Full text
Differences in Intraretinal Pigment Migration Across Inherited Retinal Dystrophies. / 09.2020 / PubMed / Full text
Exosomal MiRNA Transfer between Retinal Microglia and RPE. / 17.05.2020 / PubMed / Full text
Functionally validated imaging endpoints in the Alabama study on early age-related macular degeneration 2 (ALSTAR2): design and methods. / 19.05.2020 / PubMed / Full text
Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration. / 13.04.2020 / PubMed / Full text
CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization. / 01.04.2020 / PubMed / Full text
Extracellular microparticles exacerbate oxidative damage to retinal pigment epithelial cells. / 01.05.2020 / PubMed / Full text
Water-based continuous and interval training in older women: Cardiorespiratory and neuromuscular outcomes (WATER study). / 05.03.2020 / PubMed / Full text
Retrieval Practice Improves Recollection-Based Memory Over a Seven-Day Period in Younger and Older Adults. / 2019 / PubMed / Full text
A Comparison of Heart Rate Training Load and Perceptual Effort Between Masters and Young Cyclists / 01.05.2020 / PubMed / Full text
Retinal Pigment Epithelial Cells: The Unveiled Component in the Etiology of Prpf Splicing Factor-Associated Retinitis Pigmentosa. / 2019 / PubMed / Full text
AMPK May Play an Important Role in the Retinal Metabolic Ecosystem. / 2019 / PubMed / Full text
Stem cell-derived retinal pigment epithelium from patients with age-related macular degeneration exhibit reduced metabolism and matrix interactions. / 03.2020 / PubMed / Full text
Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptors. / 26.11.2019 / PubMed / Full text
Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina. / 19.11.2019 / PubMed / Full text
Age, lipofuscin and melanin oxidation affect fundus near-infrared autofluorescence. / 10.2019 / PubMed / Full text
Relevance of working memory for reinforcement learning in older adults varies with timescale of learning. / 09.2020 / PubMed / Full text
Expression and Function of Mas-Related G Protein-Coupled Receptor D and Its Ligand Alamandine in Retina. / 01.2020 / PubMed / Full text
The Cytoskeleton of the Retinal Pigment Epithelium: from Normal Aging to Age-Related Macular Degeneration. / 22.07.2019 / PubMed / Full text
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration. / 07.07.2019 / PubMed / Full text
Remodeling of the Basal Labyrinth of Retinal Pigment Epithelial Cells With Osmotic Challenge, Age, and Disease. / 03.06.2019 / PubMed / Full text
Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. / 08.2019 / PubMed / Full text
PML nuclear bodies are recruited to persistent DNA damage lesions in an RNF168-53BP1 dependent manner and contribute to DNA repair. / 06.2019 / PubMed / Full text
Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina. / 10.2019 / PubMed / Full text
Decreased uncoupling protein 2 expression in aging retinal pigment epithelial cells. / 2019 / PubMed / Full text
Toxicity of blue led light and A2E is associated to mitochondrial dynamics impairment in ARPE-19 cells: implications for age-related macular degeneration. / 05.2019 / PubMed / Full text
Apolipoprotein A-I Mimetic Peptide L-4F Removes Bruch's Membrane Lipids in Aged Nonhuman Primates. / 01.02.2019 / PubMed / Full text
Inhibition of Sumoylation Alleviates Oxidative Stress-induced Retinal Pigment Epithelial Cell Senescence and Represses Proinflammatory Gene Expression. / 2018 / PubMed / Full text
VEGF and PEDF levels in the rat retina: effects of aging and AMD-like retinopathy. / 2018 / PubMed
Effects of senescent secretory phenotype acquisition on human retinal pigment epithelial stem cells. / 16.11.2018 / PubMed / Full text
Active-to-Sedentary Behavior Transitions, Fatigability, and Physical Functioning in Older Adults. / 14.03.2019 / PubMed / Full text
Oxidative stress mediated by lipid metabolism contributes to high glucose-induced senescence in retinal pigment epithelium. / 01.2019 / PubMed / Full text
Flavin homeostasis in the mouse retina during aging and degeneration. / 12.2018 / PubMed / Full text
Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration. / 01.2019 / PubMed / Full text
Validity, Reliability, and Diagnostic Accuracy of Ratings of Perceived Exertion to Identify Dependence in Performing Self-care Activities in Older Women. / 10-12.2018 / PubMed / Full text
p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model. / 28.08.2018 / PubMed / Full text
PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis. / 07.08.2018 / PubMed / Full text
Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells. / 08.2018 / PubMed / Full text
Fatty acids and oxidized lipoproteins contribute to autophagy and innate immunity responses upon the degeneration of retinal pigment epithelium and development of age-related macular degeneration. / 04.2019 / PubMed / Full text
Assessment of the effect of age on macular layer thickness in a healthy Chinese cohort using spectral-domain optical coherence tomography. / 11.07.2018 / PubMed / Full text
Physiological determinants of walking effort in older adults: should they be targets for physical activity intervention? / 06.2018 / PubMed / Full text
Aging Alters Circadian Rhythms in the Mouse Eye. / 08.2018 / PubMed / Full text
The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. / 13.06.2018 / PubMed / Full text
Loss of NAMPT in aging retinal pigment epithelium reduces NAD availability and promotes cellular senescence. / 12.06.2018 / PubMed / Full text
Topographic protein profiling of the age-related proteome in the retinal pigment epithelium of Callithrix jacchus with respect to macular degeneration. / 16.01.2019 / PubMed / Full text
Longitudinal Relationship Between Interleukin-6 and Perceived Fatigability Among Well-Functioning Adults in Mid-to-Late Life. / 23.04.2019 / PubMed / Full text
Mitochondrial quality control in AMD: does mitophagy play a pivotal role? / 08.2018 / PubMed / Full text
CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length. / 08.2018 / PubMed / Full text
Anaphylatoxin Signaling in Retinal Pigment and Choroidal Endothelial Cells: Characteristics and Relevance to Age-Related Macular Degeneration. / 2018 / PubMed / Full text
Culturing of Retinal Pigment Epithelial Cells on an Ex Vivo Model of Aged Human Bruch's Membrane. / 12.04.2018 / PubMed / Full text
Role of Fibulins 2 and 5 in Retinal Development and Maintenance. / 2018 / PubMed / Full text
Fatigability and functional performance among older adults with low-normal ankle-brachial index: Cross-sectional findings from the Baltimore Longitudinal Study of Aging. / 05.2018 / PubMed / Full text
Long-term treatment with anti-VEGF does not induce cell aging in primary retinal pigment epithelium. / 06.2018 / PubMed / Full text
RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells. / 13.03.2018 / PubMed / Full text
Measuring polarization changes in the human outer retina with polarization-sensitive optical coherence tomography. / 05.2018 / PubMed / Full text
Concurrent validation of the OMNI-Resistance Exercise Scale of perceived exertion with elastic bands in the elderly. / 03.2018 / PubMed / Full text
In situ regeneration of retinal pigment epithelium by gene transfer of E2F2: a potential strategy for treatment of macular degenerations. / 12.2017 / PubMed / Full text
Differential cellular responses by oncogenic levels of c-Myc expression in long-term confluent retinal pigment epithelial cells. / 06.2018 / PubMed / Full text
Effect of aging and lifestyle on photoreceptors and retinal pigment epithelium: cross-sectional study in a healthy Danish population. / 2017 / PubMed / Full text
Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. / 15.12.2017 / PubMed / Full text
Visualizing melanosomes, lipofuscin, and melanolipofuscin in human retinal pigment epithelium using serial block face scanning electron microscopy. / 01.2018 / PubMed / Full text
Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation. / 02.2018 / PubMed / Full text
Perceived Fatigability and Objective Physical Activity in Mid- to Late-Life. / 17.04.2018 / PubMed / Full text
PKCζ-dependent upregulation of p27kip1 contributes to oxidative stress induced retinal pigment epithelial cell multinucleation. / 09.10.2017 / PubMed / Full text
Lipofuscin-mediated photic stress inhibits phagocytic activity of ARPE-19 cells; effect of donors' age and antioxidants. / 10.2017 / PubMed / Full text
Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2. / 03.2019 / PubMed / Full text
Loss of endothelial planar cell polarity and cellular clearance mechanisms in age-related macular degeneration. / 09-10.2017 / PubMed / Full text

PGC

The Aging Stress Response and Its Implication for AMD Pathogenesis. / 22.11.2020 / PubMed / Full text
Constitutive PGC-1α Overexpression in Skeletal Muscle Does Not Contribute to Exercise-Induced Neurogenesis. / 16.11.2020 / PubMed / Full text
Dysregulated Autophagy Mediates Sarcopenic Obesity and Its Complications via AMPK and PGC1α Signaling Pathways: Potential Involvement of Gut Dysbiosis as a Pathological Link. / 19.09.2020 / PubMed / Full text
Resemblance and differences in dietary restriction nephroprotective mechanisms in young and old rats. / 24.09.2020 / PubMed / Full text
Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. / 08.2020 / PubMed / Full text
PGC-1α-mediated regulation of mitochondrial function and physiological implications. / 09.2020 / PubMed / Full text
Targeting Mitochondrial Network Architecture in Down Syndrome and Aging. / 29.04.2020 / PubMed / Full text
Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner. / 06.2020 / PubMed / Full text
A novel dipeptide from potato protein hydrolysate augments the effects of exercise training against high-fat diet-induced damages in senescence-accelerated mouse-prone 8 by boosting pAMPK / SIRT1/ PGC-1α/ pFOXO3 pathway. / 26.04.2020 / PubMed / Full text
Mitochondrial nucleoid remodeling and biogenesis are regulated by the p53-p21 -PKCζ pathway in p16 -silenced cells. / 24.04.2020 / PubMed / Full text
[Metabolic Alteration in Aging Process: Metabolic Remodeling in White Adipose Tissue by Caloric Restriction]. / 2020 / PubMed / Full text
Kynurenine aminotransferase isoforms display fiber-type specific expression in young and old human skeletal muscle. / 15.02.2020 / PubMed / Full text
Ubiquinol-10 delays postovulatory oocyte aging by improving mitochondrial renewal in pigs. / 20.01.2020 / PubMed / Full text
Mitochondrial oxidative capacity and NAD biosynthesis are reduced in human sarcopenia across ethnicities. / 20.12.2019 / PubMed / Full text
MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities. / 22.08.2019 / PubMed / Full text
Constitutive PGC-1α overexpression in skeletal muscle does not protect from age-dependent decline in neurogenesis. / 23.08.2019 / PubMed / Full text
Augmentation of cellular NAD by NQO1 enzymatic action improves age-related hearing impairment. / 10.2019 / PubMed / Full text
Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. / 01.10.2019 / PubMed / Full text
PGC-1α, a potential therapeutic target against kidney aging. / 10.2019 / PubMed / Full text
Resveratrol and HIV-protease inhibitors control UCP1 expression through opposite effects on p38 MAPK phosphorylation in human adipocytes. / 02.2020 / PubMed / Full text
Peroxisome proliferator-activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging. / 10.2019 / PubMed / Full text
PGC-1a integrates a metabolism and growth network linked to caloric restriction. / 10.2019 / PubMed / Full text
PGC-1α regulates mitochondrial properties beyond biogenesis with aging and exercise training. / 01.09.2019 / PubMed / Full text
A coaching program to improve quality of life in older people in Japan: a randomised controlled trial. / 02.07.2019 / PubMed / Full text
Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation. / 2019 / PubMed / Full text
Regulation of Mitochondrial Biogenesis as a Way for Active Longevity: Interaction Between the Nrf2 and PGC-1α Signaling Pathways. / 2019 / PubMed / Full text
Effect of Initial Aging and High-Fat/High-Fructose Diet on Mitochondrial Bioenergetics and Oxidative Status in Rat Brain. / 11.2019 / PubMed / Full text
Double knockout of Akt2 and AMPK predisposes cardiac aging without affecting lifespan: Role of autophagy and mitophagy. / 01.07.2019 / PubMed / Full text
Lasting spatial learning and memory deficits following chronic cerebral hypoperfusion are associated with hippocampal mitochondrial aging in rats. / 01.09.2019 / PubMed / Full text
Early induction of senescence and immortalization in PGC-1α-deficient mouse embryonic fibroblasts. / 07.2019 / PubMed / Full text
Study on neuroendocrine-immune function of Phenylethanoid Glycosides of Desertliving Cistanche herb in perimenopausal rat model. / 28.06.2019 / PubMed / Full text
Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. / 2019 / PubMed / Full text
Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure. / 07.2019 / PubMed / Full text
Anti-inflammatory action of β-hydroxybutyrate via modulation of PGC-1α and FoxO1, mimicking calorie restriction. / 27.02.2019 / PubMed / Full text
Effects of a resistance-training programme on endoplasmic reticulum unfolded protein response and mitochondrial functions in PBMCs from elderly subjects. / 08.2019 / PubMed / Full text
6-Gingerol Improves Ectopic Lipid Accumulation, Mitochondrial Dysfunction, and Insulin Resistance in Skeletal Muscle of Ageing Rats: Dual Stimulation of the AMPK/PGC-1α Signaling Pathway via Plasma Adiponectin and Muscular AdipoR1. / 03.2019 / PubMed / Full text
Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats. / 23.12.2018 / PubMed / Full text
AMP Kinase Activation is Selectively Disrupted in the Ventral Midbrain of Mice Deficient in Parkin or PINK1 Expression. / 03.2019 / PubMed / Full text
Intensified mitophagy in skeletal muscle with aging is downregulated by PGC-1alpha overexpression in vivo. / 01.2019 / PubMed / Full text
SREBP-1c-Dependent Metabolic Remodeling of White Adipose Tissue by Caloric Restriction. / 26.10.2018 / PubMed / Full text
Sex Differences in Genetic Associations With Longevity. / 08.2018 / PubMed / Full text
Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration. / 01.2019 / PubMed / Full text
mRNA expressions of peroxisome proliferator-activated receptor gamma coactivator 1α, tumor necrosis factor-α, and interleukin-6 in paraspinal muscles of patients with lumbar kyphosis: a preliminary study. / 2018 / PubMed / Full text
Effects of Ginsenoside Rg3 on fatigue resistance and SIRT1 in aged rats. / 01.11.2018 / PubMed / Full text
PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis. / 07.08.2018 / PubMed / Full text
Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training. / 01.10.2018 / PubMed / Full text
PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ. / 02.08.2018 / PubMed / Full text
Exercise Training Protects Against Aging-Induced Cognitive Dysfunction via Activation of the Hippocampal PGC-1α/FNDC5/BDNF Pathway. / 09.2018 / PubMed / Full text
Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells. / 15.09.2018 / PubMed / Full text
Adiponectin/AdiopR1 signal inactivation contributes to impaired angiogenesis in mice of advanced age. / 15.09.2018 / PubMed / Full text
Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats. / 2018 / PubMed / Full text
Deficient mitochondrial biogenesis in IL-2 activated NK cells correlates with impaired PGC1-α upregulation in elderly humans. / 09.2018 / PubMed / Full text
Moderate Modulation of Cardiac PGC-1α Expression Partially Affects Age-Associated Transcriptional Remodeling of the Heart. / 2018 / PubMed / Full text
Mild aerobic training with blood flow restriction increases the hypertrophy index and MuSK in both slow and fast muscles of old rats: Role of PGC-1α. / 01.06.2018 / PubMed / Full text
Age-dependent regulation of antioxidant genes by p38α MAPK in the liver. / 06.2018 / PubMed / Full text
Effect of contractile activity on PGC-1α transcription in young and aged skeletal muscle. / 01.06.2018 / PubMed / Full text
Overexpression of PGC-1α in aging muscle enhances a subset of young-like molecular patterns. / 04.2018 / PubMed / Full text
The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system. / 03.2018 / PubMed / Full text
Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. / 04.2018 / PubMed / Full text
Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury. / 11.01.2018 / PubMed / Full text
Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1α pathway. / 02.2018 / PubMed / Full text
Resveratrol and/or exercise training counteract aging-associated decline of physical endurance in aged mice; targeting mitochondrial biogenesis and function. / 09.2018 / PubMed / Full text
Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. / 02.2018 / PubMed / Full text
Interleukin-6 Affects Aging-Related Changes of the PPARα-PGC-1α Axis in the Myocardium. / 12.2017 / PubMed / Full text
Panax notoginseng saponins attenuate cardiomyocyte apoptosis through mitochondrial pathway in natural aging rats. / 02.2018 / PubMed / Full text
PGC-1α affects aging-related changes in muscle and motor function by modulating specific exercise-mediated changes in old mice. / 02.2018 / PubMed / Full text
Autophagy and mitochondrial biogenesis impairment contribute to age-dependent liver injury in experimental sepsis: dysregulation of AMP-activated protein kinase pathway. / 02.2018 / PubMed / Full text
Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis. / 28.09.2017 / PubMed / Full text
AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species. / 03.10.2017 / PubMed / Full text
[Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell]. / 02.2017 / PubMed / Full text
The intracellular angiotensin system buffers deleterious effects of the extracellular paracrine system. / 07.09.2017 / PubMed / Full text
Plasticity and function of human skeletal muscle in relation to disuse and rehabilitation: Influence of ageing and surgery. / 08.2017 / PubMed
Mitochondrial-Targeted Antioxidant Maintains Blood Flow, Mitochondrial Function, and Redox Balance in Old Mice Following Prolonged Limb Ischemia. / 04.09.2017 / PubMed / Full text
A pectic polysaccharide from Ligusticum chuanxiong promotes intestine antioxidant defense in aged mice. / 15.10.2017 / PubMed / Full text
Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats. / 11.2017 / PubMed / Full text
PGC-1α in aging and lifelong exercise training-mediated regulation of UPR in mouse liver. / 11.2017 / PubMed / Full text
High glucose and free fatty acids induce endothelial progenitor cell senescence via PGC-1α/SIRT1 signaling pathway. / 10.2017 / PubMed / Full text

GC

Body Size and Cuticular Hydrocarbons as Larval Age Indicators in the Forensic Blow Fly, Chrysomya albiceps (Diptera: Calliphoridae). / 04.12.2020 / PubMed / Full text
Composition of peony petal fatty acids and flavonoids and their effect on Caenorhabditis elegans lifespan. / 10.2020 / PubMed / Full text
Photo aging and fragmentation of polypropylene food packaging materials in artificial seawater. / 01.01.2021 / PubMed / Full text
Secretory galectin-3 induced by glucocorticoid stress triggers stemness exhaustion of hepatic progenitor cells. / 04.12.2020 / PubMed / Full text
Optimization of Ethanol Detection by Automatic Headspace Method for Cellulose Insulation Aging of Oil-immersed Transformers. / 15.07.2020 / PubMed / Full text
Sensory, olfactometric and chemical characterization of the aroma potential of Garnacha and Tempranillo winemaking grapes. / 30.11.2020 / PubMed / Full text
Accelerated Cognitive Ageing in epilepsy: exploring the effective connectivity between resting-state networks and its relation to cognitive decline. / 06.2020 / PubMed / Full text
Characterization of Jinhua ham aroma profiles in specific to aging time by gas chromatography-ion mobility spectrometry (GC-IMS). / 10.2020 / PubMed / Full text
Quantitative Profiling of Lipid Species in Caenorhabditis elegans with Gas Chromatography-Mass Spectrometry. / 2020 / PubMed / Full text
Physicochemical characterization of a polysaccharide from Agrocybe aegirita and its anti-ageing activity. / 15.05.2020 / PubMed / Full text
Structural characteristics, antioxidant properties and antiaging activities of galactan produced by Mentha haplocalyx Briq. / 15.04.2020 / PubMed / Full text
Contribution of Volatile Odorous Terpenoid Compounds to Aged Cognac Spirits Aroma in a Context of Multicomponent Odor Mixtures. / 25.11.2020 / PubMed / Full text
Plasma Formate Is Greater in Fetal and Neonatal Rats Compared with Their Mothers. / 01.05.2020 / PubMed / Full text
Development of a new strategy for studying the aroma potential of winemaking grapes through the accelerated hydrolysis of phenolic and aromatic fractions (PAFs). / 01.2020 / PubMed / Full text
Compromised steady-state germinal center activity with age in nonhuman primates. / 02.2020 / PubMed / Full text
Endogenous Glucocorticoid Signaling in the Regulation of Bone and Marrow Adiposity: Lessons from Metabolism and Cross Talk in Other Tissues. / 12.2019 / PubMed / Full text
4,5-Diphenyl-2-methyl picolinate induces cellular senescence by accumulating DNA damage and activating associated signaling pathways in gastric cancer. / 01.12.2019 / PubMed / Full text
Relationship Between the Dose Administered, Target Tissue Dose, and Toxicity Level After Acute Oral Exposure to Bifenthrin and Tefluthrin in Young Adult Rats. / 01.12.2019 / PubMed / Full text
Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly. / 12.09.2019 / PubMed / Full text
Identification and analysis of new α- and β-hydroxy ketones related to the formation of 3-methyl-2,4-nonanedione in musts and red wines. / 01.02.2020 / PubMed / Full text
Neonatal T Follicular Helper Cells Are Lodged in a Pre-T Follicular Helper Stage Favoring Innate Over Adaptive Germinal Center Responses. / 2019 / PubMed / Full text
Identification of Dialkylpyrazines Off-Flavors in Oak Wood. / 11.09.2019 / PubMed / Full text
Metabolomics Coupled with Transcriptomics Approach Deciphering Age Relevance in Sepsis. / 08.2019 / PubMed / Full text
Age-Related Structural Alterations in Human Amygdala Networks: Reflections on Correlations Between White Matter Structure and Effective Connectivity. / 2019 / PubMed / Full text
Volatile Flavor Components as a Function of Electrical Stimulation and Chiller Aging for [i]m. longissimus[/i] and [i]biceps femoris[/i] of Hanwoo Beef. / 06.2019 / PubMed / Full text
Dr Foster global frailty score: an international retrospective observational study developing and validating a risk prediction model for hospitalised older persons from administrative data sets. / 22.06.2019 / PubMed / Full text
Effect of Polygonum Multiflorum Thunb on liver fatty acid content in aging mice induced by D-galactose. / 01.06.2019 / PubMed / Full text
Measurement of 11-dehydrocorticosterone in mice, rats and songbirds: Effects of age, sex and stress. / 15.09.2019 / PubMed / Full text
Influence of aging on germinal centre reaction and antibody response to inactivated influenza virus antigens in mice: sex-based differences. / 08.2019 / PubMed / Full text
Biological activity of Dittrichia viscosa (L.) Greuter extracts against adult Sitophilus granarius (L.) (Coleoptera, Curculionidae) and identification of active compounds. / 23.04.2019 / PubMed / Full text
Causal Interactions in Human Amygdala Cortical Networks across the Lifespan. / 11.04.2019 / PubMed / Full text
Reference intervals for the urinary steroid metabolome: The impact of sex, age, day and night time on human adult steroidogenesis. / 2019 / PubMed / Full text
Increased intron retention is a post-transcriptional signature associated with progressive aging and Alzheimer's disease. / 06.2019 / PubMed / Full text
Influence of water aging on surface hardness of low-shrinkage light-cured composite resins. / 28.03.2019 / PubMed / Full text
Impact of simulated biological aging on physicochemical and biocompatibility properties of cyclic olefin copolymers. / 04.2019 / PubMed / Full text
Role of Endogenous Glucocorticoids in Cancer in the Elderly. / 27.11.2018 / PubMed / Full text
Macular Inner Retinal Layer Thickness in Relation to Photopic and Mesopic Contrast Sensitivity in Healthy Young and Older Subjects. / 01.11.2018 / PubMed / Full text
New associations of the Multidimensional Prognostic Index. / 08.2019 / PubMed / Full text
The Volume of Hippocampal Subfields in Relation to Decline of Memory Recall Across the Adult Lifespan. / 2018 / PubMed / Full text
Differential expression of a stress-regulated gene Nr4a2 characterizes early- and late-born hippocampal granule cells. / 06.2019 / PubMed / Full text
Why does women's fertility end in mid-life? Grandmothering and age at last birth. / 14.01.2019 / PubMed / Full text
B cell responses to apoptotic cells in MFG-E8-/- mice. / 2018 / PubMed / Full text
Characteristic Scent from the Tahitian Liverwort, Cyathodium foetidissimum. / 2018 / PubMed / Full text
Correlation between chronological and physiological age of males from their multivariate urinary endogenous steroid profile and prostatic carcinoma-induced deviation. / 11.2018 / PubMed / Full text
Silencing of sucrose hydrolase causes nymph mortality and disturbs adult osmotic homeostasis in Diaphorina citri (Hemiptera: Liviidae). / 10.2018 / PubMed / Full text
Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-F10 cells by inducing senescence. / 15.07.2018 / PubMed / Full text
A novel colorimetric sensor array based on boron-dipyrromethene dyes for monitoring the storage time of rice. / 01.12.2018 / PubMed / Full text
Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text
[Chronicity and aging in Cardiology: Geriatric Cardiology, Cardiac Rehabilitation or Care-Related Cardiogeriatric Rehabilitation? delle cure correlate?] / 02.2018 / PubMed
Study on the effects of rapid aging technology on the aroma quality of white tea using GC-MS combined with chemometrics: In comparison with natural aged and fresh white tea. / 01.11.2018 / PubMed / Full text
Infection with phytopathogenic bacterium inhibits melatonin biosynthesis, decreases longevity of its vector, and suppresses the free radical-defense. / 10.2018 / PubMed / Full text
Impact of Increasing Levels of Oxygen Consumption on the Evolution of Color, Phenolic, and Volatile Compounds of Nebbiolo Wines. / 2018 / PubMed / Full text
Constituent and effects of polysaccharides isolated from Sophora moorcroftiana seeds on lifespan, reproduction, stress resistance, and antimicrobial capacity in Caenorhabditis elegans. / 04.2018 / PubMed / Full text
Impact of an early-exposure geriatrics curriculum in an accelerated baccalaureate-MD program. / 10-12.2020 / PubMed / Full text
Norisoprenoids, Sesquiterpenes and Terpenoids Content of Valpolicella Wines During Aging: Investigating Aroma Potential in Relationship to Evolution of Tobacco and Balsamic Aroma in Aged Wine. / 2018 / PubMed / Full text
Effects on inequality in life expectancy from a social ecology perspective. / 13.02.2018 / PubMed / Full text
Effects of stress hormones on the brain and cognition: Evidence from normal to pathological aging. / 01-03.2011 / PubMed / Full text
Extensively re-organized systemic lymph nodes provide a feasible environment for self-reactivity in lupus-prone NZB × NZW F1 mice. / 31.12.2017 / PubMed / Full text
The impact of age-class and social context on fecal glucocorticoid metabolite levels in free-ranging male giraffes. / 01.01.2018 / PubMed / Full text
Metabolic phenotyping using kinetic measurements in young and older healthy adults. / 01.2018 / PubMed / Full text
Changes in anthocyanins and volatile components of purple sweet potato fermented alcoholic beverage during aging. / 10.2017 / PubMed / Full text
Impact of Plasmopara viticola infection of Merlot and Cabernet Sauvignon grapes on wine composition and flavor. / 15.01.2018 / PubMed / Full text
The Effects of Erzincan Grape ([i]Vitis vinifera[/i] spp., [i]Cimin[/i]) and Benzothiazol on a [i]Caenorhabditis elegans[/i] Organism Model. / 07.2017 / PubMed / Full text
Similar post-stress metabolic trajectories in young and old flies. / 02.2018 / PubMed / Full text

Aging genes 60-99

CRP

RPE

PGC

GC

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