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...therapeutic target for age-related memory decline and perhaps Alzheimer's disease (AD). * Alzheimer’s disease (AD) ...

|title=Alzheimer's Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss i ...Aβ42. Therefore, we show that the mis-expression of [i]Ank2[/i] can drive disease relevant processes and phenocopy some features of AD. Therefore, we propose ...

...functions. These findings reveal that the tumor suppressor [[HACE1]] plays a role in the NRF2 antioxidative stress response pathway and in neurodegenera * Huntington Disease ...

|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. ...do we suggest novel potential risk factors among the FTD-genes interactors as targets for further mechanistic characterization in hypothesis driven cell ...

...[BAG3]] and friends: co-chaperones in selective autophagy during aging and disease. ...SP70) to misfolded proteins and also involves other protein partners, such as [[HSPB8]]. Also crucial for induction and execution of autophagy are seques ...

...knowledge on genes that regulate LTL and their impact on human health and disease. * age-related disease ...

fission regulator 1 precursor (Chondrocyte protein with a poly-proline region) [CHPPR] [FAM54A2] [KIAA0009] |title=A genome-wide scan for common variants affecting the rate of age-related cogn ...

...al dysfunction contributes to dynein-dependent neurological diseases, such as SMA-LED. |mesh-terms=* Aging ...

...t epigenetic changes, which are part of a specific osteoporosis-associated aging process. * Aging ...

|title=Chronic renal failure in a mouse model of human adenine phosphoribosyltransferase deficiency. ...creatinine clearance rates, which measure excretion of infused creatinine as an estimate of glomerular filtration rate (GFR), are about half that of wil ...

|title=Progression of early postnatal retinal pathology in a mouse model of neuronal ceroid lipofuscinosis. ...of the timing, location, and characteristic retinal pathologies of Batten disease may lead to diagnostic and therapeutic advances in the clinical setting. ...

...[BAG3]] and friends: co-chaperones in selective autophagy during aging and disease. ...SP70) to misfolded proteins and also involves other protein partners, such as [[HSPB8]]. Also crucial for induction and execution of autophagy are seques ...

...rebroside-sulfatase) [Contains: Arylsulfatase A component B; Arylsulfatase A component C] |title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. ...

|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. ...are not common factors implicated in AD. Nevertheless, our study suggests a potential pathogenic link between [[NOTCH3]], [[CSF1R]], and sporadic late- ...

|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. ...are not common factors implicated in AD. Nevertheless, our study suggests a potential pathogenic link between [[NOTCH3]], [[CSF1R]], and sporadic late- ...

|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. ...are not common factors implicated in AD. Nevertheless, our study suggests a potential pathogenic link between [[NOTCH3]], [[CSF1R]], and sporadic late- ...

...noreceptors reaches a peak in 3 months, while [[NEFM]] and [[S100B]] reach a peak in 1 year. |mesh-terms=* Aging ...

|title=A genome screen of successful aging without cognitive decline identifies [[LRP1B]] by haplotype analysis. ...haplotypes in the gene [[LRP1B]] are significant/protective for successful aging without cognitive decline. ...

...lved additional pathways. Hence, our results identify [[PINK1]] deficiency as an early modulator of innate immunity in neurons, which precedes late stage * Aging ...

...on in the [[EN1]] gene promoter: implications for understanding ageing and disease. ...ions of DNA. This has implications for the future detection of age-related disease. ...