Редактирование: Aging genes 3 (раздел)

==SIRT1==

* {{medline-title
|title=Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats.
|date=03.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274583
|full-text-url=https://sci-hub.do/10.1111/acel.13279
}}
* {{medline-title
|title=Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective.
|date=05.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33280374
|full-text-url=https://sci-hub.do/10.1021/acschemneuro.0c00696
}}
* {{medline-title
|title=Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33149857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585532
}}
* {{medline-title
|title=[[SIRT1]] Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence.
|date=04.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33158256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694272
}}
* {{medline-title
|title=Histone Deacetylase [[SIRT1]], Smooth Muscle Cell Function, and Vascular Diseases.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573826
}}
* {{medline-title
|title=6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing [[SIRT1]] and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation.
|date=27.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33111210
|full-text-url=https://sci-hub.do/10.1007/s11010-020-03951-z
}}
* {{medline-title
|title=Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through [[SIRT1]] activation and AKT/mTOR pathway inhibition.
|date=30.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010892
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.09.096
}}
* {{medline-title
|title=[[SIRT1]] Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7508177
}}
* {{medline-title
|title=The Role of Sirtuins in Kidney Diseases.
|date=12.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555196
}}
* {{medline-title
|title=The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men.
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32919015
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111090
}}
* {{medline-title
|title=Virus-Induced Asthma Exacerbations: [[SIRT1]] Targeted Approach.
|date=13.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32823491
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464235
}}
* {{medline-title
|title=Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793997
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09896-6
}}
* {{medline-title
|title=Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/[[SIRT1]]-FOXA3-Beclin1 pathway.
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768436
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111053
}}
* {{medline-title
|title=Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32722945
|full-text-url=https://sci-hub.do/10.1080/15412555.2020.1797657
}}
* {{medline-title
|title=Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of [[SIRT1]] in Human Dermal Fibroblasts.
|date=01.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32404543
|full-text-url=https://sci-hub.do/10.1248/bpb.b20-00094
}}
* {{medline-title
|title=SRT1720-induced activation of [[SIRT1]] alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485.
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32421926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327920
}}
* {{medline-title
|title=miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32292498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150474
}}
* {{medline-title
|title=Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes.
|date=01-12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153179
}}
* {{medline-title
|title=Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32249404
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09875-x
}}
* {{medline-title
|title=The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32214805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084123
}}
* {{medline-title
|title=Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158519
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048230
}}
* {{medline-title
|title=Spatiotemporal gating of [[SIRT1]] functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia.
|date=24.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32152092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104039
}}
* {{medline-title
|title=Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of [[SIRT1]].
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32132865
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053352
}}
* {{medline-title
|title=[[SIRT1]] and aging related signaling pathways.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32084459
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111215
}}
* {{medline-title
|title=Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of [[SIRT1]] signaling.
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32088214
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.117452
}}
* {{medline-title
|title=Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of [[SIRT1]] activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206476
}}
* {{medline-title
|title=Deacetylation of MRTF-A by [[SIRT1]] defies senescence induced down-regulation of collagen type I in fibroblast cells.
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061777
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165723
}}
* {{medline-title
|title=Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal [[SIRT1]] Levels Improving Cognition in Aged Rats.
|date=26.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31991916
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071257
}}
* {{medline-title
|title=Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating [[SIRT1]].
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957441
}}
* {{medline-title
|title=Two novel [[SIRT1]] activators, SCIC2 and SCIC2.1, enhance [[SIRT1]]-mediated effects in stress response and senescence.
|date=06-07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31942817
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574383
}}
* {{medline-title
|title=Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
|date=23.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31881011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949053
}}
* {{medline-title
|title=The protective role of omentin-1 in IL-1β-induced chondrocyte senescence.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31852248
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1699803
}}
* {{medline-title
|title=The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD  Level Is Lower than the Sirtuin-Saturating Concentrations.
|date=24.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31878234
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982340
}}
* {{medline-title
|title=Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells.
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214571
}}
* {{medline-title
|title=Central nervous system [[SIRT1]] expression is required for cued and contextual fear conditioning memory responses in aging mice.
|date=23.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31763496
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839599
}}
* {{medline-title
|title=Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31785216

}}
* {{medline-title
|title=CO ameliorates endothelial senescence induced by 5-fluorouracil through [[SIRT1]] activation.
|date=30.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704100
|full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108185
}}
* {{medline-title
|title=Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating [[SIRT1]] expression.
|date=20.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31631065
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398
}}
* {{medline-title
|title=The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31572218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751260
}}
* {{medline-title
|title=Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544977
|full-text-url=https://sci-hub.do/10.1002/jcp.29182
}}
* {{medline-title
|title=Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure.
|date=13.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552414
|full-text-url=https://sci-hub.do/10.1093/sleep/zsz217
}}
* {{medline-title
|title=Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of [[SIRT1]].
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710442
}}
* {{medline-title
|title=Activation of the miR-34a-Mediated [[SIRT1]]/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31420820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985387
}}