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Aging genes 70-79
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==NLRP3== * {{medline-title |title=Innate and Adaptive Immunity in Aging and Longevity: The Foundation of Resilience. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33269094 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673842 }} * {{medline-title |title=Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism. |date=06.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33212416 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680814 }} * {{medline-title |title=Panax notoginseng saponins attenuate neuroinflammation through [[TXNIP]]-mediated [[NLRP3]] inflammasome activation in aging rats. |date=10.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33176641 |full-text-url=https://sci-hub.do/10.2174/1389201021999201110204735 }} * {{medline-title |title=[[TET2]]-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity. |date=27.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33113366 |full-text-url=https://sci-hub.do/10.1016/j.celrep.2020.108326 }} * {{medline-title |title=Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and [[NLRP3]] inflammasome. |date=01.01.2021 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33115643 |full-text-url=https://sci-hub.do/10.1016/j.neulet.2020.135461 }} * {{medline-title |title=A Small Molecule Stabilizer of the [[MYC]] G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma. |date=13.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066043 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650714 }} * {{medline-title |title=Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013631 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493674 }} * {{medline-title |title=Mechanisms of [[NLRP3]] priming in inflammaging and age related diseases. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32883606 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571497 }} * {{medline-title |title=Lamivudine Inhibits [i]Alu[/i] RNA-induced Retinal Pigment Epithelium Degeneration via Anti-inflammatory and Anti-senescence Activities. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32855848 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7422901 }} * {{medline-title |title=The [[NLRP3]] Inflammasome: Metabolic Regulation and Contribution to Inflammaging. |date=30.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32751530 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463618 }} * {{medline-title |title=Aging aggravated liver ischemia and reperfusion injury by promoting STING-mediated [[NLRP3]] activation in macrophages. |date=08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32666684 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431827 }} * {{medline-title |title=Targeting [[NLRP3]] Inflammasome Reduces Age-Related Experimental Alveolar Bone Loss. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32531176 |full-text-url=https://sci-hub.do/10.1177/0022034520933533 }} * {{medline-title |title=Fatty food, fatty acids, and microglial priming in the adult and aged hippocampus and amygdala. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544595 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572563 }} * {{medline-title |title=Korean Red Ginseng Suppresses the Expression of Oxidative Stress Response and [[NLRP3]] Inflammasome Genes in Aged C57BL/6 Mouse Ovaries. |date=22.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32331214 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231237 }} * {{medline-title |title=Cepharanthine promotes the effect of dexmedetomidine on the deposition of β-amyloid in the old age of the senile dementia rat model by regulating inflammasome expression. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32337948 |full-text-url=https://sci-hub.do/10.5114/fn.2019.89855 }} * {{medline-title |title=Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice. |date=08.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268299 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185103 }} * {{medline-title |title=Ginsenoside Rg1 ameliorates glomerular fibrosis during kidney aging by inhibiting [[NOX4]] and [[NLRP3]] inflammasome activation in SAMP8 mice. |date=27.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32114413 |full-text-url=https://sci-hub.do/10.1016/j.intimp.2020.106339 }} * {{medline-title |title=Blockade of the [[NLRP3]] inflammasome improves metabolic health and lifespan in obese mice. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31975052 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206474 }} * {{medline-title |title=Autophagy and [[NLRP3]] inflammasome crosstalk in neuroinflammation in aged bovine brains. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31903559 |full-text-url=https://sci-hub.do/10.1002/jcp.29426 }} * {{medline-title |title=Cellular senescence induced by [[S100A9]] in mesenchymal stromal cells through [[NLRP3]] inflammasome activation. |date=14.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31727865 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874461 }} * {{medline-title |title=[[NLRP3]] Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity. |date=13.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31603987 |full-text-url=https://sci-hub.do/10.1093/gerona/glz239 }} * {{medline-title |title=[[NLRP3]] inflammasome suppression improves longevity and prevents cardiac aging in male mice. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31625260 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974709 }} * {{medline-title |title=Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging. |date=08.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31494646 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756903 }} * {{medline-title |title=Effect of Aging on Taurine Transporter (TauT) Expression in the Mouse Brain Cortex. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468381 |full-text-url=https://sci-hub.do/10.1007/978-981-13-8023-5_1 }} * {{medline-title |title=Tamoxifen-induced, intestinal-specific deletion of [i]Slc5a6[/i] in adult mice leads to spontaneous inflammation: involvement of NF-κB, [[NLRP3]], and gut microbiota. |date=01.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31369292 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842991 }} * {{medline-title |title=Systemic inflammation impairs microglial Aβ clearance through [[NLRP3]] inflammasome. |date=02.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31359456 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717897 }} * {{medline-title |title=Aging in the Syrian hamster testis: Inflammatory-oxidative status and the impact of photoperiod. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31276778 |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110649 }} * {{medline-title |title=[Improved effects of saponins from Panax japonicus on decline of cognitive function in natural aging rats via [[NLRP3]] inflammasome pathway]. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989956 |full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180921.001 }} * {{medline-title |title=Lack of [[NLRP3]] Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin. |date=04.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30869745 |full-text-url=https://sci-hub.do/10.1093/gerona/glz079 }} * {{medline-title |title=Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks. |date=11.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862067 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429360 }} * {{medline-title |title=[[NLRP3]]/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30720125 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423574 }} * {{medline-title |title=Mitochondrial Stress-Initiated Aberrant Activation of the [[NLRP3]] Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. |date=22.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673616 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371804 }} * {{medline-title |title=Purple sweet potato color attenuated [[NLRP3]] inflammasome by inducing autophagy to delay endothelial senescence. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585631 |full-text-url=https://sci-hub.do/10.1002/jcp.28003 }} * {{medline-title |title=Inhibiting the [[NLRP3]] Inflammasome With MCC950 Ameliorates Isoflurane-Induced Pyroptosis and Cognitive Impairment in Aged Mice. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30524241 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262296 }} * {{medline-title |title=Klotho controls the brain-immune system interface in the choroid plexus. |date=27.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30413620 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275534 }} * {{medline-title |title=[[NLRP3]] inflammasome activation in inflammaging. |date=12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30268598 |full-text-url=https://sci-hub.do/10.1016/j.smim.2018.09.001 }} * {{medline-title |title=Melatonin and inflammation-Story of a double-edged blade. |date=11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242884 |full-text-url=https://sci-hub.do/10.1111/jpi.12525 }} * {{medline-title |title=A response to readers' comments. |date=14.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217141 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138902 }} * {{medline-title |title=[[NLRP3]] inflammasome-dependent pyroptosis is proposed to be involved in the mechanism of age-dependent isoflurane-induced cognitive impairment. |date=14.09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217191 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138927 }} * {{medline-title |title=Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30065258 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146930 }} * {{medline-title |title=Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain. |date=06.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896426 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988593 }} * {{medline-title |title=Critical role of [[NLRP3]]-caspase-1 pathway in age-dependent isoflurane-induced microglial inflammatory response and cognitive impairment. |date=17.04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29665808 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904978 }} * {{medline-title |title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149 }} * {{medline-title |title=AMP-Activated Protein Kinase Regulation of the [[NLRP3]] Inflammasome during Aging. |date=01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29150317 |full-text-url=https://sci-hub.do/10.1016/j.tem.2017.10.009 }} * {{medline-title |title=Effects of chronically increased VEGF-A on the aging heart. |date=03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146733 |full-text-url=https://sci-hub.do/10.1096/fj.201700761RR }} * {{medline-title |title=[[NLRP3]] inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection. |date=01.03.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097427 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900358 }} * {{medline-title |title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. |date=05.10.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149 }} * {{medline-title |title=Specific calpain inhibition protects kidney against inflammaging. |date=14.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28808241 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556007 }} * {{medline-title |title=Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress. |date=28.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28659507 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509458 }} * {{medline-title |title=The [[NLRP3]] inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice. |date=01.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28536183 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582883 }} * {{medline-title |title=Human Plasma Thioredoxin-80 Increases With Age and in ApoE Mice Induces Inflammation, Angiogenesis, and Atherosclerosis. |date=01.08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473446 |full-text-url=https://sci-hub.do/10.1161/CIRCULATIONAHA.117.027612 }} * {{medline-title |title=Metaflammation: Tissue-Specific Alterations of the [[NLRP3]] Inflammasome Platform in Metabolic Syndrome. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28403789 |full-text-url=https://sci-hub.do/10.2174/0929867324666170407123522 }} * {{medline-title |title=Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of Apc mice. |date=11.04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28397782 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394268 }} * {{medline-title |title=β-Hydroxybutyrate Deactivates Neutrophil [[NLRP3]] Inflammasome to Relieve Gout Flares. |date=28.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28249154 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527297 }} * {{medline-title |title=Vascular endothelial cells senescence is associated with NOD-like receptor family pyrin domain-containing 3 ([[NLRP3]]) inflammasome activation via reactive oxygen species (ROS)/thioredoxin-interacting protein ([[TXNIP]]) pathway. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28064010 |full-text-url=https://sci-hub.do/10.1016/j.biocel.2017.01.001 }} * {{medline-title |title=Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27845246 |full-text-url=https://sci-hub.do/10.1016/j.bbalip.2016.11.003 }} * {{medline-title |title=Aging-Associated [[TNF]] Production Primes Inflammasome Activation and [[NLRP3]]-Related Metabolic Disturbances. |date=01.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27566828 |full-text-url=https://sci-hub.do/10.4049/jimmunol.1501336 }} * {{medline-title |title=Hepatic NAD( ) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27174364 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945761 }} * {{medline-title |title=Age-Dependent Susceptibility to Pulmonary Fibrosis Is Associated with [[NLRP3]] Inflammasome Activation. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26933834 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979364 }} * {{medline-title |title=Increased VEGF-A promotes multiple distinct aging diseases of the eye through shared pathomechanisms. |date=01.03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912740 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772957 }} * {{medline-title |title=Growth Hormone Receptor Deficiency Protects against Age-Related [[NLRP3]] Inflammasome Activation and Immune Senescence. |date=23.02.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26876170 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992590 }} * {{medline-title |title=Same molecule but different expression: aging and sepsis trigger [[NLRP3]] inflammasome activation, a target of melatonin. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26681113 |full-text-url=https://sci-hub.do/10.1111/jpi.12303 }} * {{medline-title |title=Nod-like receptor pyrin containing 3 ([[NLRP3]]) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26540403 |full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2015.10.015 }} * {{medline-title |title=Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448778 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596365 }} * {{medline-title |title=A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379247 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575031 }} * {{medline-title |title=Purple sweet potato color inhibits endothelial premature senescence by blocking the [[NLRP3]] inflammasome. |date=10.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26164602 |full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2015.04.012 }} * {{medline-title |title=Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye. |date=24.06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26104676 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486438 }} * {{medline-title |title=A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in mice. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26030099 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464010 }} * {{medline-title |title=Drivers of age-related inflammation and strategies for healthspan extension. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25879284 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400872 }} * {{medline-title |title=DAMPs as mediators of sterile inflammation in aging-related pathologies. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25641058 |full-text-url=https://sci-hub.do/10.1016/j.arr.2015.01.003 }} * {{medline-title |title=Protective effect of telmisartan on neurovascular unit and inflammasome in stroke-resistant spontaneously hypertensive rats. |date=06.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25591419 |full-text-url=https://sci-hub.do/10.1179/1743132815Y.0000000002 }} * {{medline-title |title=P2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the [[NLRP3]]/ASC/caspase 1 pathway. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24022661 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038356 }} * {{medline-title |title=Deep tissue injury in development of pressure ulcers: a decrease of inflammasome activation and changes in human skin morphology in response to aging and mechanical load. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23967056 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743891 }} * {{medline-title |title=Differential pathways for interleukin-1β production activated by chromogranin A and amyloid β in microglia. |date=12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23831373 |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2013.05.018 }}
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