Редактирование: ELN (раздел)

==Publications==

{{medline-entry
|title=Curcumin enhances the production of major structural components of elastic fibers, elastin, and fibrillin-1, in normal human fibroblast cells.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25333322
|abstract=Curcumin is the major component of the yellow extract derived from the rhizome of the Curcuma longa, which is also a main bioactive polyphenol and has been generally used as a spice, food additive, and herbal medicine. In this presented study, we found that curcumin can enhance the production of major structural components of elastic fibers, elastin, and fibrillin-1, in normal human fibroblast cells via increasing [[ELN]] and FBN1 promoters' activities. With 2 μM curcumin treatment, the enhanced tropoelastin and fibrillin-1 protein amounts in Detroit 551 cells were approximately 134 and 130% of control, respectively. Therefore, our results demonstrated that curcumin may be used as a functional compound and applied to drugs, foods, and cosmetics in the future.
|mesh-terms=* Aging
* Cell Line
* Curcumin
* Elastic Tissue
* Elastin
* Fibrillin-1
* Fibrillins
* Fibroblasts
* Humans
* Microfilament Proteins
* Promoter Regions, Genetic
* RNA, Messenger
* Tropoelastin
|keywords=* curcumin
* elastin
* fibrillin-1
* fibroblast cells
* promoter activity
|full-text-url=https://sci-hub.do/10.1080/09168451.2014.972324
}}