Редактирование: CRISP2 (раздел)

==Publications==

{{medline-entry
|title=Novel development-related alternative splices in human testis identified by cDNA microarrays.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/15713825
|abstract=Alternative splicing of premessenger RNA is an important regulatory mechanism that increases the diversity of proteins transcribed from a single gene. This is particularly important in the testis because germ cell expansion and differentiation require many cellular changes and regulatory steps. To investigate novel development-related alternative splicings in the human testis, complementary DNA microarray studies were conducted with the use of probes from human fetal testes, adult testes, and human spermatozoa. Of a total of 386 Unigene clusters found to be related to the development of the testis, 67 clusters showed a total of 74 novel alternative spliceoforms. Developmental stage-dependent expression was also performed for a novel Unigene, NYD-SP20 (Hs.351068), which had 4 possible novel spliceoforms and another Unigene, [[CRISP2]] (cysteine-rich secretory protein 2, Hs.2042), which had 3 possible novel spliceoforms. These results indicate that alternative splicing plays an important role in the complicated processes of testis development and spermatogenesis.
|mesh-terms=* Adult
* Aged
* Aging
* Alternative Splicing
* Base Sequence
* DNA Primers
* DNA, Complementary
* Gene Expression Regulation, Developmental
* Humans
* Male
* Oligonucleotide Array Sequence Analysis
* Proteins
* RNA, Messenger
* Spermatozoa
* Testis

|full-text-url=https://sci-hub.do/10.1002/j.1939-4640.2005.tb01085.x
}}