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Aging genes 3
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==CD4== * {{medline-title |title=Identification of Key Genes and Potential New Biomarkers for Ovarian Aging: A Study Based on RNA-Sequencing Data. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304387 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701310 }} * {{medline-title |title=Distinct Age-Related Epigenetic Signatures in [[CD4]] and CD8 T Cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33262764 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686576 }} * {{medline-title |title=IL-1β-MyD88-mTOR Axis Promotes Immune-Protective IL-17A Foxp3 Cells During Mucosal Infection and Is Dysregulated With Aging. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33240286 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677307 }} * {{medline-title |title=Thymus involution sets the clock of declined immunity and repair with aging. |date=25.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33248315 |full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101231 }} * {{medline-title |title=Food insecurity and T-cell dysregulation in women living with HIV on antiretroviral therapy. |date=28.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33247896 |full-text-url=https://sci-hub.do/10.1093/cid/ciaa1771 }} * {{medline-title |title=Rapamycin Eyedrops Increased [[CD4]] Foxp3 Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface. |date=24.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33255287 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727717 }} * {{medline-title |title=Antioxidants N-Acetylcysteine and Vitamin C Improve T Cell Commitment to Memory and Long-Term Maintenance of Immunological Memory in Old Mice. |date=19.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33228213 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7699597 }} * {{medline-title |title=Evolution of comorbidities in people living with HIV between 2004 and 2014: cross-sectional analyses from ANRS CO3 Aquitaine cohort. |date=16.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33198667 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670698 }} * {{medline-title |title=Impact of age on [[CD4]] recovery and viral suppression over time among adults living with HIV who initiated antiretroviral therapy in the African Cohort Study. |date=12.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33183355 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664082 }} * {{medline-title |title=hPMSCs protects against D-galactose-induced oxidative damage of [[CD4]] T cells through activating Akt-mediated Nrf2 antioxidant signaling. |date=04.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33148324 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641865 }} * {{medline-title |title=Substantial gap in primary care: older adults with HIV presenting late to care. |date=31.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33129258 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603686 }} * {{medline-title |title=Quantitative Digitography Measures Fine Motor Disturbances in Chronically Treated HIV Similar to Parkinson's Disease. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33132893 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575770 }} * {{medline-title |title=Monocyte and T Cell Immune Phenotypic Profiles Associated With Age Advancement Differ Between People With HIV, Lifestyle-Comparable Controls and Blood Donors. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33123168 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573236 }} * {{medline-title |title=HIV and three dimensions of Wisdom: Association with cognitive function and physical and mental well-being: For: Psychiatry Research. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33096437 |full-text-url=https://sci-hub.do/10.1016/j.psychres.2020.113510 }} * {{medline-title |title=CD8 T cells are present at low levels in the white matter with physiological and pathological aging. |date=13.10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33049712 |full-text-url=https://sci-hub.do/10.18632/aging.104043 }} * {{medline-title |title=Immunotherapy in older patients with cancer. |date=26.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33041248 |full-text-url=https://sci-hub.do/10.1016/j.bj.2020.07.009 }} * {{medline-title |title=Multiple genetic programs contribute to [[CD4]] T cell memory differentiation and longevity by maintaining T cell quiescence. |date=11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32987276 |full-text-url=https://sci-hub.do/10.1016/j.cellimm.2020.104210 }} * {{medline-title |title=Conventional Treatment for Multiple Myeloma Drives Premature Aging Phenotypes and Metabolic Dysfunction in T Cells. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013907 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494758 }} * {{medline-title |title=Immunosenescence: the role of age in multiple sclerosis. |date=19.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32962809 |full-text-url=https://sci-hub.do/10.1016/j.nrl.2020.05.016 }} * {{medline-title |title=Umbilical cord mesenchymal stem cells protect thymus structure and function in aged C57 mice by downregulating aging-related genes and upregulating autophagy- and anti-oxidative stress-related genes. |date=14.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32924972 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521525 }} * {{medline-title |title=Impaired Cytotoxic CD8 T Cell Response in Elderly COVID-19 Patients. |date=18.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32948688 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502863 }} * {{medline-title |title=What are the roles of antibodies versus a durable, high quality T-cell response in protective immunity against SARS-CoV-2? |date=11.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32875286 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7452821 }} * {{medline-title |title=Per2 Upregulation in Circulating Hematopoietic Progenitor Cells During Chronic HIV Infection. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850472 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396677 }} * {{medline-title |title=COVID-19: age, Interleukin-6, C-reactive protein, and lymphocytes as key clues from a multicentre retrospective study. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32802142 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426672 }} * {{medline-title |title=Immunosenescence profiles are not associated with muscle strength, physical performance and sarcopenia risk in very old adults: The Newcastle 85+ Study. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32735896 |full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111321 }} * {{medline-title |title=Homeostasis and the functional roles of [[CD4]] Treg cells in aging. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32717201 |full-text-url=https://sci-hub.do/10.1016/j.imlet.2020.07.004 }} * {{medline-title |title=A Comprehensive Evaluation of the Impact of Bovine Milk Containing Different Beta-Casein Profiles on Gut Health of Ageing Mice. |date=19.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32707687 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400800 }} * {{medline-title |title=Premature aging of circulating T cells predicts all-cause mortality in hemodialysis patients. |date=13.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32660510 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359274 }} * {{medline-title |title=In-depth immune cellular profiling reveals sex-specific associations with frailty. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32582361 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310472 }} * {{medline-title |title=CD70 contributes to age-associated T cell defects and overwhelming inflammatory responses. |date=19.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32559178 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343466 }} * {{medline-title |title=Comparison of Overall and Comorbidity-Free Life Expectancy Between Insured Adults With and Without HIV Infection, 2000-2016. |date=01.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32539152 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296391 }} * {{medline-title |title=Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model. |date=11.06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32545199 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313015 }} * {{medline-title |title=Thymus aging in mice deficient in either EphB2 or EphB3, two master regulators of thymic epithelium development. |date=10.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32506584 |full-text-url=https://sci-hub.do/10.1002/dvdy.212 }} * {{medline-title |title=CD8 T-cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with PARN and DKC1 mutations. |date=09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32452087 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521304 }} * {{medline-title |title=Short-Term Environmental Enrichment is a Stronger Modulator of Brain Glial Cells and Cervical Lymph Node T Cell Subtypes than Exercise or Combined Exercise and Enrichment. |date=25.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32451728 |full-text-url=https://sci-hub.do/10.1007/s10571-020-00862-x }} * {{medline-title |title=Viral and host factors related to the clinical outcome of COVID-19. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434211 |full-text-url=https://sci-hub.do/10.1038/s41586-020-2355-0 }} * {{medline-title |title=Use of comedications and potential drug-drug interactions in people living with HIV in China. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32354599 |full-text-url=https://sci-hub.do/10.1016/j.jiac.2020.04.003 }} * {{medline-title |title=[[CD4]] T helper 17 cell response of aged mice promotes prostate cancer cell migration and invasion. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32356608 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310589 }} * {{medline-title |title=The Rules of Human T Cell Fate [i]in vivo[/i]. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32322253 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156550 }} * {{medline-title |title=[[CD4]]/CD8 ratio, comorbidities, and aging in treated HIV infected individuals on viral suppression. |date=21.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32314818 |full-text-url=https://sci-hub.do/10.1002/jmv.25911 }} * {{medline-title |title=The effects of advanced maternal age on T-cell subsets at the maternal-fetal interface prior to term labor and in the offspring: a mouse study. |date=07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32279324 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290081 }} * {{medline-title |title=Structural and Functional Changes in the Mesenteric Lymph Nodes in Humans during Aging. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32248450 |full-text-url=https://sci-hub.do/10.1007/s10517-020-04782-0 }} * {{medline-title |title=Neurocognitive Functioning is Associated with Self-Reported and Performance-Based Treatment Management Abilities in People Living with HIV with Low Health Literacy. |date=24.07.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32090235 |full-text-url=https://sci-hub.do/10.1093/arclin/acaa005 }} * {{medline-title |title=Blockade of Stat3 oncogene addiction induces cellular senescence and reveals a cell-nonautonomous activity suitable for cancer immunotherapy. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32064174 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996562 }} * {{medline-title |title=Age-related changes in T lymphocytes of patients with head and neck squamous cell carcinoma. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32082401 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017629 }} * {{medline-title |title=Immunological history governs human stem cell memory [[CD4]] heterogeneity via the Wnt signaling pathway. |date=10.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041953 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010798 }} * {{medline-title |title=Estimating HIV Management and Comorbidity Costs Among Aging HIV Patients in the United States: A Systematic Review. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32011956 |full-text-url=https://sci-hub.do/10.18553/jmcp.2020.26.2.104 }} * {{medline-title |title=Sex Differences in People Aging With HIV. |date=01.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32032279 |full-text-url=https://sci-hub.do/10.1097/QAI.0000000000002259 }} * {{medline-title |title=Identification of Differentially Expressed miRNAs in the Response of Spleen [[CD4]] T Cells to Electroacupuncture in Senescence-Accelerated Mice. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32026263 |full-text-url=https://sci-hub.do/10.1007/s12013-020-00900-x }} * {{medline-title |title=Thymus Involution and Intravenous Drug Abuse. |date=03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32000220 |full-text-url=https://sci-hub.do/10.1097/PAF.0000000000000530 }} * {{medline-title |title=Depletion of [[CD4]] T cells provides therapeutic benefits in aged mice after ischemic stroke. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31954116 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059209 }} * {{medline-title |title=Immunological and Virological Responses in Older HIV-Infected Adults Receiving Antiretroviral Therapy: An Evidence-Based Meta-Analysis. |date=01.04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31913990 |full-text-url=https://sci-hub.do/10.1097/QAI.0000000000002266 }} * {{medline-title |title=African Mitochondrial DNA Haplogroup L2 Is Associated With Slower Decline of β-cell Function and Lower Incidence of Diabetes Mellitus in Non-Hispanic, Black Women Living With Human Immunodeficiency Virus. |date=05.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31927570 |full-text-url=https://sci-hub.do/10.1093/cid/ciaa026 }} * {{medline-title |title=DP1 Activation Reverses Age-Related Hypertension Via NEDD4L-Mediated T-Bet Degradation in T Cells. |date=25.02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31893939 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