LRP1

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Prolow-density lipoprotein receptor-related protein 1 precursor (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen) [Contains: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] [A2MR] [APR]

Publications[править]

Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome.


LXR activation protects hippocampal microvasculature in very old triple transgenic mouse model of Alzheimer's disease.


Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1.


Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats.


Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice.


LRP1 protects the vasculature by regulating levels of connective tissue growth factor and HtrA1.


A lipoprotein receptor cluster IV mutant preferentially binds amyloid-β and regulates its clearance from the mouse brain.