E2F3

Материал из hpluswiki
Перейти к навигации Перейти к поиску

Transcription factor E2F3 (E2F-3) [KIAA0075]

Publications[править]

Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution.


miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions.


Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution.


Tumor-suppressive microRNA-449a induces growth arrest and senescence by targeting E2F3 in human lung cancer cells.


Elevated miR-34c-5p mediates dermal fibroblast senescence by ultraviolet irradiation.


Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland.


E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas.


Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo.