DMPK

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Myotonin-protein kinase (EC 2.7.11.1) (MT-PK) (DM-kinase) (DMK) (DM1 protein kinase) (DMPK) (Myotonic dystrophy protein kinase) [DM1PK] [MDPK]

Publications[править]

Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans.


Expanded CTG repeats trigger miRNA alterations in Drosophila that are conserved in myotonic dystrophy type 1 patients.


DM1 CTG expansions affect insulin receptor isoforms expression in various tissues of transgenic mice.


Fen1 does not control somatic hypermutability of the (CTG)(n)*(CAG)(n) repeat in a knock-in mouse model for DM1.


Transgenic overexpression of human DMPK accumulates into hypertrophic cardiomyopathy, myotonic myopathy and hypotension traits of myotonic dystrophy.


The pleiotropic expression of the myotonic dystrophy protein kinase gene illustrates the complex relationships between genetic, biological and clinical covariates of male aging.


Developmental expression of myotonic dystrophy protein kinase in brain and its relevance to clinical phenotype.


Skeletal muscle sodium channel gating in mice deficient in myotonic dystrophy protein kinase.


Progressive atrioventricular conduction block in a mouse myotonic dystrophy model.