UST
Uronyl 2-sulfotransferase (EC 2.8.2.-) [DS2ST]
Publications[править]
Changes occur in muscles and nerves with aging. In this study we explore the relationship between unipedal stance time (UST) and frontal plane hip and ankle sensorimotor function in subjects with diabetic neuropathy. UST, quantitative measures of frontal plane ankle proprioceptive thresholds, and ankle and hip motor function were tested in 41 subjects with a spectrum of lower limb sensorimotor function ranging from healthy to moderately severe diabetic neuropathy. Frontal plane hip and ankle sensorimotor function demonstrated significant relationships with UST. Multivariate analysis identified only composite hip strength, ankle proprioceptive threshold, and age to be significant predictors of UST (R(2) = 0.73), explaining 46%, 24%, and 3% of the variance, respectively. Frontal plane hip strength was the single best predictor of UST and appeared to compensate for less precise ankle proprioceptive thresholds. This finding is clinically relevant given the possibility of strengthening the hip, even in patients with significant peripheral neuropathy.
MeSH Terms
- Aged
- Aged, 80 and over
- Aging
- Ankle
- Body Mass Index
- Data Interpretation, Statistical
- Diabetic Neuropathies
- Electromyography
- Female
- Hip
- Humans
- Male
- Middle Aged
- Muscle Strength
- Neurologic Examination
- Postural Balance
- Proprioception
- Regression Analysis
- Time Factors