LAPTM4B

Материал из hpluswiki
Версия от 16:39, 12 мая 2021; OdysseusBot (обсуждение | вклад) (Новая страница: «Lysosomal-associated transmembrane protein 4B (Lysosome-associated transmembrane protein 4-beta) [PSEC0001] ==Publications== {{medline-entry |title=Expression o...»)
(разн.) ← Предыдущая версия | Текущая версия (разн.) | Следующая версия → (разн.)
Перейти к навигации Перейти к поиску

Lysosomal-associated transmembrane protein 4B (Lysosome-associated transmembrane protein 4-beta) [PSEC0001]

Publications[править]

Expression of 25 high egg production related transcripts that identified from hypothalamus and pituitary gland in red-feather Taiwan country chickens.

Expression levels of 33 high egg production candidate transcripts in Red-feather Taiwan country chickens (TCCs) were examined by quantitative reverse-transcription (RT) polymerase chain reactions (PCR) in this study. Candidate transcripts were previously identified from a L2-B (L2-subtract-B) hypothalamus/pituitary gland subtractive cDNA library. In this subtractive cDNA library, two divergently selected strains of TCCs, B and L2 were used. These two strains were originated from one single population and were further subjected (since 1982) to the selections of body weight/comb size (B) and eggs to 40wk of age (L2), respectively. Hypothalamuses and pituitary glands that sampled from Red-feather TCCs were previously grouped into high (Red-high; n=20) and low (Red-low; n=20) egg productions based on the rate of lay after 1st egg (hen-day laying rate; %). Rates of lay after 1st egg (mean /-S.E.) in the Red-high and the Red-low subpopulations were 72.2 /-0.6 and 23.0 /-3.5, respectively (P<0.01). Quantitative RT-PCR validated that 25 candidate transcripts were significantly higher expressed in the Red-high than in the Red-low hens. These transcripts were ANP32A, BDH, CDC42, CNTN1, COMT, CPE, CTNNB1, DIO2, EIF4E, GARNL1, HSPCA, LAPTM4B, MBP, NAP1L4, NCAM1, PARK7, PCDHA@, PGDS, PLAG1, PRL, RAD21, SAR1A, SCG2, STMN1 and UFM1. Among these transcripts, 15 (79.0%), 13 (68.4%), and 12 (63.2%) genes were annotated to involve in cellular physiological process (GO:0050875), metabolism (GO:0008152) and cell communication (GO:0007154). Identified transcripts that related to high egg production are most active in focal adhesion, adherens junction, MAPK signaling, tight junction and cell adhesion pathways.

MeSH Terms

  • Aging
  • Animals
  • Chickens
  • Color
  • Feathers
  • Female
  • Gene Expression Profiling
  • Gene Expression Regulation
  • Hypothalamus
  • Oviposition
  • Pituitary Gland
  • Taiwan
  • Transcription, Genetic