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Редактирование:
Aging genes 60-99
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==TERT== * {{medline-title |title=Telomeres and telomerase in risk assessment of cardiovascular diseases. |date=15.12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33171154 |full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.112361 }} * {{medline-title |title=A 4-Base-Pair Core-Enclosing Helix in Telomerase RNA Is Essential for Activity and for Binding to the Telomerase Reverse Transcriptase Catalytic Protein Subunit. |date=20.11.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33046533 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685517 }} * {{medline-title |title=Angiotensin inhibition and cellular senescence in the developing rat kidney. |date=12.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33010296 |full-text-url=https://sci-hub.do/10.1016/j.yexmp.2020.104551 }} * {{medline-title |title=Decreased expression of [[TERT]] and telomeric proteins as human ovaries age may cause telomere shortening. |date=27.08.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856217 |full-text-url=https://sci-hub.do/10.1007/s10815-020-01932-1 }} * {{medline-title |title=The secrets of telomerase: Retrospective analysis and future prospects. |date=15.09.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32698073 |full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118115 }} * {{medline-title |title=Gene expression in human mesenchymal stem cell aging cultures: modulation by short peptides. |date=06.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399807 |full-text-url=https://sci-hub.do/10.1007/s11033-020-05506-3 }} * {{medline-title |title=Unravelling Cellular Mechanisms of Stem Cell Senescence: An Aid from Natural Bioactive Molecules. |date=20.03.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32244882 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150900 }} * {{medline-title |title=Expression of telomerase reverse transcriptase positively correlates with duration of lithium treatment in bipolar disorder. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32114208 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334059 }} * {{medline-title |title=FAM96B inhibits the senescence of dental pulp stem cells. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32039527 |full-text-url=https://sci-hub.do/10.1002/cbin.11319 }} * {{medline-title |title=Aging and biomarkers: Transcriptional levels evaluation of Osteopontin/miRNA-181a axis in hepatic tissue of rats in different age ranges. |date=05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32061643 |full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110879 }} * {{medline-title |title=Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31978617 |full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115252 }} * {{medline-title |title=Characterization of human telomerase reverse transcriptase immortalized anterior cruciate ligament cell lines. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31948601 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962762 }} * {{medline-title |title=Mitochondria, Telomeres and Telomerase Subunits. |date=2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781563 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851022 }} * {{medline-title |title=Towards Therapeutic Alternatives for Mercury Neurotoxicity in the Amazon: Unraveling the Pre-Clinical Effects of the Superfruit Açaí ([i]Euterpe oleracea[/i], Mart.) as Juice for Human Consumption. |date=26.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31717801 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893510 }} * {{medline-title |title=Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing. |date=08.10.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31597307 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801922 }} * {{medline-title |title=Telomerase Biology Associations Offer Keys to Cancer and Aging Therapeutics. |date=2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544708 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403649 }} * {{medline-title |title=Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts. |date=17.09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31481614 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754593 }} * {{medline-title |title=[[TERT]] assists [[GDF11]] to rejuvenate senescent VEGFR2 /CD133 cells in elderly patients with myocardial infarction. |date=11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292540 |full-text-url=https://sci-hub.do/10.1038/s41374-019-0290-1 }} * {{medline-title |title=Telomerase Reverse Transcriptase ([[TERT]]) in Action: Cross-Talking with Epigenetics. |date=07.07.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31284662 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651578 }} * {{medline-title |title=Role of Senescence and Neuroprotective Effects of Telomerase in Neurodegenerative Diseases. |date=04.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170886 |full-text-url=https://sci-hub.do/10.1089/rej.2018.2115 }} * {{medline-title |title=Telomerase reverse transcriptase ameliorates lung fibrosis by protecting alveolar epithelial cells against senescence. |date=31.05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31000627 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552422 }} * {{medline-title |title=Analysis of the Association Between [i]TERC[/i] and [i][[TERT]][/i] Genetic Variation and Leukocyte Telomere Length and Human Lifespan-A Follow-Up Study. |date=25.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30691026 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409517 }} * {{medline-title |title=Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. |date=23.01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30673631 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366955 }} * {{medline-title |title=Tissue iron is negatively correlated with TERC or [[TERT]] mRNA expression: A heterochronic parabiosis study in mice. |date=16.12.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30555055 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326661 }} * {{medline-title |title=Cell cycle-dependent and -independent telomere shortening accompanies murine brain aging. |date=20.11.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472697 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286833 }} * {{medline-title |title=Extended proliferation of chicken- and Okinawa rail-derived fibroblasts by expression of cell cycle regulators. |date=05.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30417340 |full-text-url=https://sci-hub.do/10.1002/jcp.27417 }} * {{medline-title |title=The Telomerase Complex Directly Controls Hematopoietic Stem Cell Differentiation and Senescence in an Induced Pluripotent Stem Cell Model of Telomeropathy. |date=2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210531 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123533 }} * {{medline-title |title=Clinical Implications of Clonal Hematopoiesis. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30078412 |full-text-url=https://sci-hub.do/10.1016/j.mayocp.2018.04.002 }} * {{medline-title |title=Contact-independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025223 |full-text-url=https://sci-hub.do/10.1016/j.molimm.2018.07.017 }} * {{medline-title |title=Possible association of the [[TERT]] promoter polymorphisms rs2735940, rs7712562 and rs2853669 with diabetes mellitus in obese elderly Polish population: results from the national PolSenior study. |date=08.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29938393 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060992 }} * {{medline-title |title=Telomerase May Paradoxically Accelerate Aging of the DNA Methylome. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667924 |full-text-url=https://sci-hub.do/10.1089/rej.2018.2073 }} * {{medline-title |title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. |date=05.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171 }} * {{medline-title |title=GWAS of epigenetic aging rates in blood reveals a critical role for [[TERT]]. |date=26.01.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29374233 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786029 }} * {{medline-title |title=Curcumin Affects Adipose Tissue-Derived Mesenchymal Stem Cell Aging Through [[TERT]] Gene Expression. |date=04.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29017189 |full-text-url=https://sci-hub.do/10.1055/s-0043-119635 }} * {{medline-title |title=Rat adipose-derived mesenchymal stem cells aging reduction by zinc sulfate under extremely low frequency electromagnetic field exposure is associated with increased telomerase reverse transcriptase gene expression. |date=Spring.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28785382 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524544 }} * {{medline-title |title=Accelerated cellular senescence as underlying mechanism for functionally impaired bone marrow-derived progenitor cells in ischemic heart disease. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28434530 |full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2017.03.023 }} * {{medline-title |title=Cinnamaldehyde and eugenol change the expression folds of [[AKT1]] and [[DKC1]] genes and decrease the telomere length of human adipose-derived stem cells (hASCs): An experimental and in silico study. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28392905 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378970 }} * {{medline-title |title=Immortalized prairie vole-derived fibroblasts (VMF-K4DTs) can be transformed into pluripotent stem cells and provide a useful tool with which to determine optimal reprogramming conditions. |date=21.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28331164 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481634 }} * {{medline-title |title=Comprehensive Analysis of Interaction Networks of Telomerase Reverse Transcriptase with Multiple Bioinformatic Approaches: Deep Mining the Potential Functions of Telomere and Telomerase. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28281877 |full-text-url=https://sci-hub.do/10.1089/rej.2016.1909 }} * {{medline-title |title=Differential decrease in soluble and DNA-bound telomerase in senescent human fibroblasts. |date=08.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28251405 |full-text-url=https://sci-hub.do/10.1007/s10522-017-9688-6 }} * {{medline-title |title=Sex-dependent telomere shortening, telomerase activity and oxidative damage in marine medaka Oryzias melastigma during aging. |date=30.11.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28129920 |full-text-url=https://sci-hub.do/10.1016/j.marpolbul.2017.01.021 }} * {{medline-title |title=Autophagy induction reduces telomerase activity in HeLa cells. |date=04.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28043814 |full-text-url=https://sci-hub.do/10.1016/j.mad.2016.12.011 }} * {{medline-title |title=Common variants of human [[TERT]] and TERC genes and susceptibility to sporadic Alzheimers disease. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039025 |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.12.017 }} * {{medline-title |title=Establishment and application of a novel patient-derived KIAA1549:[[BRAF]]-driven pediatric pilocytic astrocytoma model for preclinical drug testing. |date=14.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28002790 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355278 }} * {{medline-title |title=Regulation of the Human Telomerase Gene [[TERT]] by Telomere Position Effect-Over Long Distances (TPE-OLD): Implications for Aging and Cancer. |date=12.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27977688 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5169358 }} * {{medline-title |title=Targeting of multiple senescence-promoting genes and signaling pathways by triptonide induces complete senescence of acute myeloid leukemia cells. |date=15.02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27908660 |full-text-url=https://sci-hub.do/10.1016/j.bcp.2016.11.024 }} * {{medline-title |title=Increased Telomerase Reverse Transcriptase Expression Associates with Spontaneous Exit from M-II Arrest in Rat Eggs. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27898217 |full-text-url=https://sci-hub.do/10.1089/cell.2016.0036 }} * {{medline-title |title=Low p16 Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27859428 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548187 }} * {{medline-title |title=Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein [[TERT]] within mitochondria. |date=22.10.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27777385 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115906 }} * {{medline-title |title=Telomere length is regulated by FGF-2 in human embryonic stem cells and affects the life span of its differentiated progenies. |date=02.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27757766 |full-text-url=https://sci-hub.do/10.1007/s10522-016-9662-8 }} * {{medline-title |title=Role of Telomerase in the Cardiovascular System. |date=17.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27322328 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929428 }} * {{medline-title |title=Stimulation of cell proliferation by glutathione monoethyl ester in aged bone marrow stromal cells is associated with the assistance of [[TERT]] gene expression and telomerase activity. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27251157 |full-text-url=https://sci-hub.do/10.1007/s11626-016-0021-5 }} * {{medline-title |title=Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations. |date=02.06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27252083 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895768 }} * {{medline-title |title=Neuroprotective effects of the catalytic subunit of telomerase: A potential therapeutic target in the central nervous system. |date=07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27095058 |full-text-url=https://sci-hub.do/10.1016/j.arr.2016.04.004 }} * {{medline-title |title=Clinical Characteristics and Prognostic Significance of [[TERT]] Promoter Mutations in Cancer: A Cohort Study and a Meta-Analysis. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26799744 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723146 }} * {{medline-title |title=[Vitamin C promotes in vitro proliferation of bone marrow mesenchymal stem cells derived from aging mice]. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26714898 }} * {{medline-title |title=Increased expression of telomere-regulating genes in endurance athletes with long leukocyte telomeres. |date=15.01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26586905 |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00587.2015 }} * {{medline-title |title=A novel autosomal recessive [[TERT]] T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34 hematopoietic stem cells not reversible by mTOR-inhibition. |date=11.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26546739 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694062 }} * {{medline-title |title=Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs. |date=25.12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26518879 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692211 }} * {{medline-title |title=Anti-aging effect of estrogen on telomerase activity in ovariectomised rats--animal model for menopause. |date=07.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26340354 |full-text-url=https://sci-hub.do/10.3109/09513590.2015.1065478 }} * {{medline-title |title=Telomerase activity promotes osteoblast differentiation by modulating IGF-signaling pathway. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26260615 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602053 }} * {{medline-title |title=Tissue formation and tissue engineering through host cell recruitment or a potential injectable cell-based biocomposite with replicative potential: Molecular mechanisms controlling cellular senescence and the involvement of controlled transient telomerase activation therapies. |date=12.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26034007 |full-text-url=https://sci-hub.do/10.1002/jbm.a.35515 }} * {{medline-title |title=The impact of immunosenescence on humoral immune response variation after influenza A/H1N1 vaccination in older subjects. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25816015 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376784 }} * {{medline-title |title=Stromal cell-derived factor-1α prevents endothelial progenitor cells senescence and enhances re-endothelialization of injured arteries via human telomerase reverse transcriptase. |date=08.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25820929 |full-text-url=https://sci-hub.do/10.1002/cbin.10471 }} * {{medline-title |title=Telomerase redux: ready for prime time? |date=04.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25790341 |full-text-url=https://sci-hub.do/10.1089/rej.2015.1695 }} * {{medline-title |title=Transient delivery of modified mRNA encoding [[TERT]] rapidly extends telomeres in human cells. |date=05.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25614443 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415018 }} * {{medline-title |title=Telomere length and the risk of atrial fibrillation: insights into the role of biological versus chronological aging. |date=12.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25381796 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294941 }} * {{medline-title |title=Chronic sleep fragmentation induces endothelial dysfunction and structural vascular changes in mice. |date=01.11.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25364077 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196065 }} * {{medline-title |title=The MNS16A polymorphism in the [[TERT]] gene in peri-centenarians from the Han Chinese population. |date=10.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25216705 |full-text-url=https://sci-hub.do/10.1007/s11427-014-4723-1 }} * {{medline-title |title=Molecular cloning and measurement of telomerase reverse transcriptase ([[TERT]]) transcription patterns in tissues of European hake (Merluccius merluccius) and Atlantic cod (Gadus morhua) during aging. |date=10.05.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24607378 |full-text-url=https://sci-hub.do/10.1016/j.gene.2014.03.006 }} * {{medline-title |title=Cellular functions of the dual-targeted catalytic subunit of telomerase, telomerase reverse transcriptase--potential role in senescence and aging. |date=08.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24583100 |full-text-url=https://sci-hub.do/10.1016/j.exger.2014.02.011 }} * {{medline-title |title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. |date=2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567 }} * {{medline-title |title=Polymorphisms within the Telomerase Reverse Transcriptase gene ([[TERT]]) in four breeds of dogs selected for difference in lifespan and cancer susceptibility. |date=14.01.2014 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24423165 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904191 }}
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