Aging genes 300

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  • Acute, exercise-induced alterations in cytokines and chemokines in the blood distinguish physically active and sedentary aging. / 08.12.2020 / PubMed / Full text
  • Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe mice: role of SIRT1. / 18.11.2020 / PubMed / Full text
  • Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism. / 06.11.2020 / PubMed / Full text
  • Anti-aging effect of DL-β-hydroxybutyrate against hepatic cellular senescence induced by D-galactose or γ-irradiation via autophagic flux stimulation in male rats. / 01-02.2021 / PubMed / Full text
  • Exploring the extensive crosstalk between the antagonistic cytokines- TGF-β and TNF-α in regulating cancer pathogenesis. / 03.11.2020 / PubMed / Full text
  • ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19. / 2020 / PubMed / Full text
  • Repeated propofol exposure-induced neuronal damage and cognitive impairment in aged rats by activation of NF-κB pathway and NLRP3 inflammasome. / 01.01.2021 / PubMed / Full text
  • Long non-coding RNA SNHG29 regulates cell senescence via p53/p21 signaling in spontaneous preterm birth. / 15.10.2020 / PubMed / Full text
  • Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress. / 2020 / PubMed / Full text
  • Cognition Is Associated With Peripheral Immune Molecules in Healthy Older Adults: A Cross-Sectional Study. / 2020 / PubMed / Full text
  • Human innate immune cell crosstalk induces melanoma cell senescence. / 30.08.2020 / PubMed / Full text
  • Anti-aging effects of [i]Ribes meyeri[/i] anthocyanins on neural stem cells and aging mice. / 12.09.2020 / PubMed / Full text
  • Effects of a four week detraining period on physical, metabolic, and inflammatory profiles of elderly women who regularly participate in a program of strength training. / 2020 / PubMed / Full text
  • Contribution of Porphyromonas gingivalis lipopolysaccharide to experimental periodontitis in relation to aging. / 26.08.2020 / PubMed / Full text
  • New MoDC-Targeting TNF Fusion Proteins Enhance Cyclic Di-GMP Vaccine Adjuvanticity in Middle-Aged and Aged Mice. / 2020 / PubMed / Full text
  • Cognitive impairment in elderly patients with rheumatic disease and the effect of disease-modifying anti-rheumatic drugs. / 30.08.2020 / PubMed / Full text
  • Cotinine ameliorates memory and learning impairment in senescent mice. / 11.2020 / PubMed / Full text
  • Kynurenines link chronic inflammation to functional decline and physical frailty. / 20.08.2020 / PubMed / Full text
  • Voluntary exercise training attenuated the middle-aged maturity-induced cardiac apoptosis. / 15.10.2020 / PubMed / Full text
  • Preclinical Evaluation of a Food-Derived Functional Ingredient to Address Skeletal Muscle Atrophy. / 29.07.2020 / PubMed / Full text
  • Childhood survivors of high-risk neuroblastoma show signs of immune recovery and not immunosenescence. / 12.2020 / PubMed / Full text
  • FK506 induces lung lymphatic endothelial cell senescence and downregulates LYVE-1 expression, with associated decreased hyaluronan uptake. / 31.07.2020 / PubMed / Full text
  • Late-onset hypogonadism: Reductio ad absurdum of the cardiovascular risk-benefit of testosterone replacement therapy. / 11.2020 / PubMed / Full text
  • Doxorubicin generates senescent microglia that exhibit altered proteomes, higher levels of cytokine secretion, and a decreased ability to internalize amyloid β. / 15.10.2020 / PubMed / Full text
  • Time restricted feeding provides a viable alternative to alternate day fasting when evaluated in terms of redox homeostasis in rats. / 16.07.2020 / PubMed / Full text
  • Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy. / 2020 / PubMed / Full text
  • Chrysin Impact on Oxidative and Inflammation Damages in the Liver of Aged Male Rats. / 17.07.2020 / PubMed / Full text
  • Correction of immunosuppression in aged septic rats by human ghrelin and growth hormone through the vagus nerve-dependent inhibition of TGF-β production. / 16.07.2020 / PubMed / Full text
  • Aging aggravated liver ischemia and reperfusion injury by promoting STING-mediated NLRP3 activation in macrophages. / 08.2020 / PubMed / Full text
  • Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients. / 10.2020 / PubMed / Full text
  • [i]Andrographis paniculata[/i] and Its Bioactive Diterpenoids Against Inflammation and Oxidative Stress in Keratinocytes. / 17.06.2020 / PubMed / Full text
  • Etanercept improves aging-induced cognitive deficits by reducing inflammation and vascular dysfunction in rats. / 01.10.2020 / PubMed / Full text
  • Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients. / 09.2020 / PubMed / Full text
  • Bone marrow mesenchymal stem cells improve thymus and spleen function of aging rats through affecting P21/PCNA and suppressing oxidative stress. / 19.06.2020 / PubMed / Full text
  • Glycolic acid adjusted to pH 4 stimulates collagen production and epidermal renewal without affecting levels of proinflammatory TNF-alpha in human skin explants. / 24.06.2020 / PubMed / Full text
  • A20 of nucleus pulposus cells plays a self-protection role via the nuclear factor-kappa B pathway in the inflammatory microenvironment. / 05.2020 / PubMed / Full text
  • Age-associated decline in neural, endocrine, and immune responses in men and women: Involvement of intracellular signaling pathways. / 15.08.2020 / PubMed / Full text
  • Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults. / 2020 / PubMed / Full text
  • Activation of FoxO1/SIRT1/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis. / 12.06.2020 / PubMed / Full text
  • The senescence-associated secretome as an indicator of age and medical risk. / 18.06.2020 / PubMed / Full text
  • The beneficial effect of physical exercise on inflammatory makers in older individuals. / 06.06.2020 / PubMed / Full text
  • Comparison of Donepezil, Memantine, Melatonin, and Liuwei Dihuang Decoction on Behavioral and Immune Endocrine Responses of Aged Senescence-Accelerated Mouse Resistant 1 Mice. / 2020 / PubMed / Full text
  • Exercise Partially Rejuvenates Muscle Stem Cells. / 06.2020 / PubMed / Full text
  • Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress. / 08.2020 / PubMed / Full text
  • Potential therapeutic effects of endothelial cells trans-differentiated from Wharton's Jelly-derived mesenchymal stem cells on altered vascular functions in aged diabetic rat model. / 2020 / PubMed / Full text
  • [Effect of fragmented sleep on postoperative cognitive function and central neuroinflammation]. / 05.05.2020 / PubMed / Full text
  • CXCL9 and CXCL10 display an age-dependent profile in Chagas patients: a cohort study of aging in Bambui, Brazil. / 11.05.2020 / PubMed / Full text
  • Can blocking inflammation enhance immunity during aging? / 05.2020 / PubMed / Full text
  • [[[FAS]]- and TNF-dependent ways participation in apoptosis mechanisms in hypotalumus in physiological and pathological aging.] / 2020 / PubMed
  • Ultrasound-guided continuous thoracic paravertebral block alleviates postoperative delirium in elderly patients undergoing esophagectomy: A randomized controlled trial. / 04.2020 / PubMed / Full text
  • 17β-Estradiol improves insulin signalling and insulin resistance in the aged female hearts: Role of inflammatory and anti-inflammatory cytokines. / 15.07.2020 / PubMed / Full text
  • Synergistic Antitumor Efficacy of Magnetohyperthermia and Poly(lactic-co-glycolic acid)-Encapsulated Selol in Ehrlich Breast Adenocarcinoma Treatment in Elderly Swiss Mice. / 01.02.2020 / PubMed / Full text
  • Pinitol suppresses TNF-α-induced chondrocyte senescence. / 19.03.2020 / PubMed / Full text
  • [Aging of skin fibroblasts: genetic and epigenetic factors.] / 2019 / PubMed
  • Functional and traditional training improve muscle power and reduce proinflammatory cytokines in older women: A randomized controlled trial. / 01.07.2020 / PubMed / Full text
  • Associations of TNF-α -308 G>A and TNF-β 252 A>G with Physical Function and BNP-Rugao Longevity and Ageing Study. / 2020 / PubMed / Full text
  • 3D TECA hydrogel reduces cellular senescence and enhances fibroblasts migration in wound healing. / 07.2018 / PubMed / Full text
  • Regulatory Effect of Anwulignan on the Immune Function Through Its Antioxidation and Anti-Apoptosis in D-Galactose-Induced Aging Mice. / 2020 / PubMed / Full text
  • Pretreatment Frailty Is Independently Associated With Increased Risk of Infections After Immunosuppression in Patients With Inflammatory Bowel Diseases. / 06.2020 / PubMed / Full text
  • The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1. / 2020 / PubMed / Full text
  • Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population. / 03.2020 / PubMed / Full text
  • In the Absence of a TCR Signal IL-2/IL-12/18-Stimulated γδ T Cells Demonstrate Potent Anti-Tumoral Function Through Direct Killing and Senescence Induction in Cancer Cells. / 04.01.2020 / PubMed / Full text
  • Aging is associated with loss of beneficial effects of estrogen on leptin responsiveness in mice fed high fat diet: Role of estrogen receptor α and cytokines. / 03.2020 / PubMed / Full text
  • Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease? / 2019 / PubMed / Full text
  • Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents. / 01.02.2020 / PubMed / Full text
  • Oral Administration of Okara Soybean By-Product Attenuates Cognitive Impairment in a Mouse Model of Accelerated Aging. / 03.12.2019 / PubMed / Full text
  • Electric vagal nerve stimulation inhibits inflammation and improves early postoperation cognitive dysfunction in aged rats. / 23.11.2019 / PubMed / Full text
  • Metformin decreases LPS-induced inflammatory response in rabbit annulus fibrosus stem/progenitor cells by blocking HMGB1 release. / 26.11.2019 / PubMed / Full text
  • Active vitamin D supplementation alleviates initiation and progression of nonalcoholic fatty liver disease by repressing the p53 pathway. / 15.01.2020 / PubMed / Full text
  • The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro. / 11.12.2019 / PubMed / Full text
  • Arsenic induces human chondrocyte senescence and accelerates rat articular cartilage aging. / 01.2020 / PubMed / Full text
  • Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content. / 08.11.2019 / PubMed / Full text
  • Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161-expressing cells. / 12.2019 / PubMed / Full text
  • Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians. / 26.11.2019 / PubMed / Full text
  • Gut microbiota combined with metabolomics reveals the metabolic profile of the normal aging process and the anti-aging effect of FuFang Zhenshu TiaoZhi(FTZ) in mice. / 01.2020 / PubMed / Full text
  • Intervertebral disc ageing and degeneration: The antiapoptotic effect of oestrogen. / 01.2020 / PubMed / Full text
  • Bone marrow-derived mesenchymal stem cells in three-dimensional co-culture attenuate degeneration of nucleus pulposus cells. / 30.10.2019 / PubMed / Full text
  • MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages. / 30.01.2020 / PubMed / Full text
  • NF-κB signaling in skin aging. / 12.2019 / PubMed / Full text
  • Aerobic exercise modulates cytokine profile and sleep quality in elderly. / 06.2019 / PubMed / Full text
  • Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. / 10.2019 / PubMed / Full text
  • Trehalose targets Nrf2 signal to alleviate d-galactose induced aging and improve behavioral ability. / 01.01.2020 / PubMed / Full text
  • Anti-Inflammatory and Anti-Aging Evaluation of Pigment-Protein Complex Extracted from [i]Chlorella Pyrenoidosa[/i]. / 16.10.2019 / PubMed / Full text
  • Inflammatory mediators and the risk of falls among older women with acute low back pain: data from Back Complaints in the Elders (BACE)-Brazil. / 03.2020 / PubMed / Full text
  • Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders. / 03.10.2019 / PubMed / Full text
  • Study on Metabolic Trajectory of Liver Aging and the Effect of Fufang Zhenzhu Tiaozhi on Aging Mice. / 2019 / PubMed / Full text
  • Culture Model for Non-human Primate Choroid Plexus. / 2019 / PubMed / Full text
  • Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults. / 13.07.2020 / PubMed / Full text
  • Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia. / 14.09.2019 / PubMed / Full text
  • [Investigation of signal molecules in saliva: prospects of application for diagnostics of myocardial infarction and the aging rate of different age people.] / 2019 / PubMed
  • Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice. / 14.08.2019 / PubMed / Full text
  • Moderate hyperoxia induces senescence in developing human lung fibroblasts. / 01.11.2019 / PubMed / Full text
  • Aging-related carcinoembryonic antigen-related cell adhesion molecule 1 signaling promotes vascular dysfunction. / 12.2019 / PubMed / Full text
  • Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APP /PS1 Transgenic Mice. / 2019 / PubMed / Full text
  • Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. / 09.2019 / PubMed / Full text
  • Knockout of longevity gene Sirt1 in zebrafish leads to oxidative injury, chronic inflammation, and reduced life span. / 2019 / PubMed / Full text
  • Glycation of macrophages induces expression of pro-inflammatory cytokines and reduces phagocytic efficiency. / 29.07.2019 / PubMed / Full text
  • Tamoxifen-induced, intestinal-specific deletion of [i]Slc5a6[/i] in adult mice leads to spontaneous inflammation: involvement of NF-κB, NLRP3, and gut microbiota. / 01.10.2019 / PubMed / Full text
  • Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. / 22.07.2019 / PubMed / Full text
  • Inflammatory markers and bone health in postmenopausal women: a cross-sectional overview. / 2019 / PubMed / Full text
  • TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. / 29.08.2019 / PubMed / Full text
  • Plasma Cells Are Obligate Effectors of Enhanced Myelopoiesis in Aging Bone Marrow. / 20.08.2019 / PubMed / Full text
  • Aging-induced elevation in circulating complement C1q level is associated with arterial stiffness. / 09.2019 / PubMed / Full text
  • Immune Mechanisms Underlying Susceptibility to Endotoxin Shock in Aged Hosts: Implication in Age-Augmented Generalized Shwartzman Reaction. / 02.07.2019 / PubMed / Full text
  • Inflammation-related genes are associated with epigenetic aging in HIV. / 12.2019 / PubMed / Full text
  • Function, Oxidative, and Inflammatory Stress Parameters in Immune Cells as Predictive Markers of Lifespan throughout Aging. / 2019 / PubMed / Full text
  • The Impact of Prophylactic Lacosamide on LPS-Induced Neuroinflammation in Aged Rats. / 10.2019 / PubMed / Full text
  • Impaired sleep quality is associated with concurrent elevations in inflammatory markers: are post-menopausal women at greater risk? / 08.07.2019 / PubMed / Full text
  • Potential effects of rapeseed peptide Maillard reaction products on aging-related disorder attenuation and gut microbiota modulation in d-galactose induced aging mice. / 17.07.2019 / PubMed / Full text
  • Ellagic acid dose and time-dependently abrogates d-galactose-induced animal model of aging: Investigating the role of PPAR-γ. / 01.09.2019 / PubMed / Full text
  • Lactobacillus sp. improved microbiota and metabolite profiles of aging rats. / 08.2019 / PubMed / Full text
  • Local and systemic effects of aging on acute pancreatitis. / 07.2019 / PubMed / Full text
  • Salicin prevents TNF-α-induced cellular senescence in human umbilical vein endothelial cells (HUVECs). / 12.2019 / PubMed / Full text
  • Age-related dynamics of pro-inflammatory cytokines in equine bronchoalveolar lavage (BAL) fluid and peripheral blood from horses managed on pasture. / 09.2019 / PubMed / Full text
  • The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity. / 06.2019 / PubMed / Full text
  • The effects of vitamin-rich carbohydrate pretreatment on the surgical stress response and S-100β after splenectomy in elderly rats. / 15.05.2019 / PubMed / Full text
  • Stem Cell-Derived Exosomes Prevent Aging-Induced Cardiac Dysfunction through a Novel Exosome/lncRNA MALAT1/NF-[i]κ[/i]B/TNF-[i]α[/i] Signaling Pathway. / 2019 / PubMed / Full text
  • Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK. / 10.2019 / PubMed / Full text
  • Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet. / 09.2019 / PubMed / Full text
  • Age-related cytokine effects on cancer-related fatigue and quality of life in acute myeloid leukemia. / 04.2020 / PubMed / Full text
  • Protective effect of vildagliptin on TNF-α-induced chondrocyte senescence. / 07.2019 / PubMed / Full text
  • Platelet-Rich Plasma (PRP) From Older Males With Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation. / 08.2019 / PubMed / Full text
  • Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway. / 15.07.2019 / PubMed / Full text
  • Protective effects of pyrroloquinoline quinine against oxidative stress-induced cellular senescence and inflammation in human renal tubular epithelial cells via Keap1/Nrf2 signaling pathway. / 07.2019 / PubMed / Full text
  • Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice. / 02.05.2019 / PubMed / Full text
  • Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with type 2 diabetes. / 08.2019 / PubMed / Full text
  • Resveratrol attenuates inflammation environment-induced nucleus pulposus cell senescence [i]in vitro[/i]. / 31.05.2019 / PubMed / Full text
  • Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. / 2019 / PubMed / Full text
  • Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention. / 06.2019 / PubMed / Full text
  • 2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. / 01.04.2019 / PubMed / Full text
  • N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms. / 05.2019 / PubMed / Full text
  • Neuroprotective Effect of Dioscin on the Aging Brain. / 30.03.2019 / PubMed / Full text
  • CSF Cytokines in Aging, Multiple Sclerosis, and Dementia. / 2019 / PubMed / Full text
  • Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. / 07.2019 / PubMed / Full text
  • A double-blind, randomized trial on the effect of a broad-spectrum dietary supplement on key biomarkers of cellular aging including inflammation, oxidative stress, and DNA damage in healthy adults. / 04.01.2017 / PubMed / Full text
  • A New Understanding of the Role of IL-1 in Age-Related Intervertebral Disc Degeneration in a Murine Model. / 08.2019 / PubMed / Full text
  • Methane ameliorates post-operative cognitive dysfunction by inhibiting microglia NF-κB/MAPKs pathway and promoting IL-10 expression in aged mice. / 06.2019 / PubMed / Full text
  • Age-dependent hepatic alterations induced by a high-fat high-fructose diet. / 05.2019 / PubMed / Full text
  • The senescent status of endothelial cells affects proliferation, inflammatory profile and SOX2 expression in bone marrow-derived mesenchymal stem cells. / 06.2019 / PubMed / Full text
  • Reduced CXCL1/GRO chemokine plasma levels are a possible biomarker of elderly depression. / 15.04.2019 / PubMed / Full text
  • Nontuberculous mycobacterium M. avium infection predisposes aged mice to cardiac abnormalities and inflammation. / 06.2019 / PubMed / Full text
  • Epigenetic Age Acceleration in Adolescence Associates With BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease. / 01.07.2019 / PubMed / Full text
  • Converging Paths of Pulmonary Arterial Hypertension and Cellular Senescence. / 07.2019 / PubMed / Full text
  • Gender-specific association of body composition with inflammatory and adipose-related markers in healthy elderly Europeans from the NU-AGE study. / 09.2019 / PubMed / Full text
  • Lifelong aerobic exercise protects against inflammaging and cancer. / 2019 / PubMed / Full text
  • Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. / 06.2019 / PubMed / Full text
  • The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature. / 01.08.2019 / PubMed / Full text
  • Impact of simulated biological aging on physicochemical and biocompatibility properties of cyclic olefin copolymers. / 04.2019 / PubMed / Full text
  • Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation. / 2018 / PubMed / Full text
  • Lifelong exercise practice and immunosenescence: Master athletes cytokine response to acute exercise. / 03.2019 / PubMed / Full text
  • Human T2R38 Bitter Taste Receptor Expression in Resting and Activated Lymphocytes. / 2018 / PubMed / Full text
  • Ameliorative effect of supercritical fluid extract of Chrysanthemum indicum Linnén against D-galactose induced brain and liver injury in senescent mice via suppression of oxidative stress, inflammation and apoptosis. / 24.04.2019 / PubMed / Full text
  • [Effect of saponins extracted from Panax japonicas on inhibiting myocardial fibrosis by TGF-β1/Smad3 signaling pathway in aging rats]. / 11.2018 / PubMed / Full text
  • Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA DHA. / 06.2019 / PubMed / Full text
  • CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2. / 2018 / PubMed / Full text
  • Role of Exercise in Vascular Function and Inflammatory Profile in Age-Related Obesity. / 2018 / PubMed / Full text
  • Establishment of a lethal aged mouse model of human respiratory syncytial virus infection. / 01.2019 / PubMed / Full text
  • Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs. / 03.2019 / PubMed / Full text
  • Effect of Myricetin on Primary Open-angle Glaucoma. / 2018 / PubMed / Full text
  • Chronic rhinosinusitis in elderly patients is associated with an exaggerated neutrophilic proinflammatory response to pathogenic bacteria. / 03.2019 / PubMed / Full text
  • Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence. / 2018 / PubMed / Full text
  • Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. / 11.12.2018 / PubMed / Full text
  • Association of pro-inflammatory cytokines and monocyte subtypes in older and younger patients on clinical outcomes after mechanical circulatory support device implantation. / 02.2019 / PubMed / Full text
  • Adipose TSHB in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence. / 2018 / PubMed / Full text
  • Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. / 05.2019 / PubMed / Full text
  • Higher levels of tumor necrosis factor β are associated with frailty in socially vulnerable community-dwelling older adults. / 06.11.2018 / PubMed / Full text
  • Epigenetics of Delirium and Aging: Potential Role of DNA Methylation Change on Cytokine Genes in Glia and Blood Along With Aging. / 2018 / PubMed / Full text
  • Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats. / 11.2018 / PubMed / Full text
  • Ellagic acid reveals promising anti-aging effects against d-galactose-induced aging on human neuroblastoma cell line, SH-SY5Y: A mechanistic study. / 12.2018 / PubMed / Full text
  • The Neuro-Immuno-Senescence Integrative Model (NISIM) on the Negative Association Between Parasympathetic Activity and Cellular Senescence. / 2018 / PubMed / Full text
  • Human umbilical cord blood plasma alleviates age-related olfactory dysfunction by attenuating peripheral TNF-α expression. / 04.2019 / PubMed / Full text
  • Manipulating fenestrations in young and old liver sinusoidal endothelial cells. / 01.01.2019 / PubMed / Full text
  • The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease. / 10.2018 / PubMed / Full text
  • Myeloid cell-derived tumor necrosis factor-alpha promotes sarcopenia and regulates muscle cell fusion with aging muscle fibers. / 12.2018 / PubMed / Full text
  • mRNA expressions of peroxisome proliferator-activated receptor gamma coactivator 1α, tumor necrosis factor-α, and interleukin-6 in paraspinal muscles of patients with lumbar kyphosis: a preliminary study. / 2018 / PubMed / Full text
  • Leptin stimulates the release of pro-inflammatory cytokines in hypothalamic astrocyte cultures from adult and aged rats. / 12.2018 / PubMed / Full text
  • Effects of 8-week kettlebell training on body composition, muscle strength, pulmonary function, and chronic low-grade inflammation in elderly women with sarcopenia. / 02.10.2018 / PubMed / Full text
  • Research advances in the regulation of the putative ovarian germline stem cell niche on female germline stem cells. / 04.2019 / PubMed / Full text
  • Efficacy and safety of biological agents in the older rheumatoid arthritis patients compared to Young: A systematic review and meta-analysis. / 04.2019 / PubMed / Full text
  • Leptin, hsCRP, TNF-α and IL-6 levels from normal aging to dementia: Relationship with cognitive and functional status. / 10.2018 / PubMed / Full text
  • Systemic Inflammation Mediates Age-Related Cognitive Deficits. / 2018 / PubMed / Full text
  • Featured Article: Deterioration of visual function mediated by senescence-associated endoplasmic reticulum stress in inflammatory tie2-TNF mice. / 08.2018 / PubMed / Full text
  • Quercetin Enhances Ligand-induced Apoptosis in Senescent Idiopathic Pulmonary Fibrosis Fibroblasts and Reduces Lung Fibrosis In Vivo. / 01.2019 / PubMed / Full text
  • Bioactive Peptide Improves Diet-Induced Hepatic Fat Deposition and Hepatocyte Proinflammatory Response in SAMP8 Ageing Mice. / 2018 / PubMed / Full text
  • Senescence and odontoblastic differentiation of dental pulp cells. / 01.2018 / PubMed / Full text
  • Effect of resistance training on inflammatory markers of older adults: A meta-analysis. / 01.10.2018 / PubMed / Full text
  • Heat-induced extracellular HSP72 release is blunted in elderly diabetic people compared with healthy middle-aged and older adults, but it is partially restored by resistance training. / 01.10.2018 / PubMed / Full text
  • Repeated abortion in adulthood induces cognition impairment in aged mice. / 30.07.2018 / PubMed / Full text
  • Cumulus cell-released tumor necrosis factor (TNF)-α promotes post-ovulatory aging of mouse oocytes. / 26.07.2018 / PubMed / Full text
  • Comparison of neurotoxicity of dexmedetomidine as an adjuvant in brachial plexus block in rats of different age. / 09-10.2018 / PubMed / Full text
  • Inflammatory cytokines and immune system modulation by aerobic versus resisted exercise training for elderly. / 03.2018 / PubMed / Full text
  • Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood. / 15.02.2019 / PubMed / Full text
  • Inhibition of programmed necrosis limits infarct size through altered mitochondrial and immune responses in the aged female rat heart. / 01.11.2018 / PubMed / Full text
  • Accumulation of T-helper 22 cells, interleukin-22 and myeloid-derived suppressor cells promotes gastric cancer progression in elderly patients. / 07.2018 / PubMed / Full text
  • Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text
  • The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. / 13.06.2018 / PubMed / Full text
  • Regulation of p38 mitogen-activated kinase-mediated fetal membrane senescence by statins. / 10.2018 / PubMed / Full text
  • Identification of proteins potentially associated with renal aging in rats. / 14.06.2018 / PubMed / Full text
  • Aerobic Exercise Protects from Pseudomonas aeruginosa-Induced Pneumonia in Elderly Mice. / 2018 / PubMed / Full text
  • Serum Tumor Necrosis Factor-alpha associates with Myocardial Oxygen Demand and Exercise Tolerance in Postmenopausal Women. / 2018 / PubMed / Full text
  • Exercise related anxiety-like behaviours are mediated by TNF receptor signaling, but not depression-like behaviours. / 15.09.2018 / PubMed / Full text
  • Accelerated vascular aging and persistent cognitive impairment in older female breast cancer survivors. / 06.2018 / PubMed / Full text
  • Features of Cytokine Profile in Different Age Groups. / 2014 / PubMed / Full text
  • Anthocyanins Improve Hippocampus-Dependent Memory Function and Prevent Neurodegeneration via JNK/Akt/GSK3β Signaling in LPS-Treated Adult Mice. / 01.2019 / PubMed / Full text
  • Supplementation with eicosapentaenoic acid and docosahexaenoic acid reduces high levels of circulating proinflammatory cytokines in aging adults: A randomized, controlled study. / 05.2018 / PubMed / Full text
  • Effects of nutritional state, aging and high chronic intake of sucrose on brain protein synthesis in rats: modulation of it by rutin and other micronutrients. / 23.05.2018 / PubMed / Full text
  • Plasma zinc in institutionalized elderly individuals: Relation with immune and cardiometabolic biomarkers. / 12.2018 / PubMed / Full text
  • Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. / 2018 / PubMed / Full text
  • Necroptosis increases with age and is reduced by dietary restriction. / 08.2018 / PubMed / Full text
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  • Estrogen upregulates inflammatory signals through NF-κB, IFN-γ, and nitric oxide via Akt/mTOR pathway in the lymph node lymphocytes of middle-aged female rats. / 12.2015 / PubMed / Full text
  • Influence of caffeine on 3,4-methylenedioxymethamphetamine-induced dopaminergic neuron degeneration and neuroinflammation is age-dependent. / 01.2016 / PubMed / Full text
  • Associations of Circulating Soluble Tumor Necrosis Factor-α Receptors 1 and 2 with Interleukin-6 Levels in an Aging Cohort of Injection Drug Users with or at High Risk for HIV Infection. / 12.2015 / PubMed / Full text
  • Chronic inflammation and risk of colorectal and other obesity-related cancers: The health, aging and body composition study. / 01.03.2016 / PubMed / Full text
  • IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation. / 15.09.2015 / PubMed / Full text
  • A Mitochondrion-Targeted Antioxidant Ameliorates Isoflurane-Induced Cognitive Deficits in Aging Mice. / 2015 / PubMed / Full text
  • Exacerbation of tumor necrosis factor-induced vascular leak syndrome by aging. / 08.2015 / PubMed / Full text
  • Skeletal muscle cells possess a 'memory' of acute early life TNF-α exposure: role of epigenetic adaptation. / 06.2016 / PubMed / Full text
  • Migrational changes of mesenchymal stem cells in response to cytokines, growth factors, hypoxia, and aging. / 15.10.2015 / PubMed / Full text
  • GADD34-deficient mice develop obesity, nonalcoholic fatty liver disease, hepatic carcinoma and insulin resistance. / 28.08.2015 / PubMed / Full text
  • Effects of 6-month supplementation with β-hydroxy-β-methylbutyrate, glutamine and arginine on vascular endothelial function of older adults. / 02.2016 / PubMed / Full text
  • Monocyte Phenotype and Polyfunctionality Are Associated With Elevated Soluble Inflammatory Markers, Cytomegalovirus Infection, and Functional and Cognitive Decline in Elderly Adults. / 05.2016 / PubMed / Full text
  • Age-related increased prevalence of asthma and nasal polyps in chronic rhinosinusitis and its association with altered IL-6 trans-signaling. / 11.2015 / PubMed / Full text
  • Inflammatory Markers Change with Age, but do not Fall Beyond Reported Normal Ranges. / 06.2016 / PubMed / Full text
  • Oral treatment with herbal formula B307 alleviates cardiac failure in aging R6/2 mice with Huntington's disease via suppressing oxidative stress, inflammation, and apoptosis. / 2015 / PubMed / Full text
  • Plasma TNF-α Is Associated with Inflammation and Nutrition Status in Community-Dwelling Japanese Elderly. / 2015 / PubMed / Full text
  • Senescent profile of angiogenic T cells from systemic lupus erythematosus patients. / 03.2016 / PubMed / Full text
  • Effects of home-based bench step exercise on inflammatory cytokines and lipid profiles in elderly Japanese females: A randomized controlled trial. / 11-12.2015 / PubMed / Full text
  • Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age. / 2015 / PubMed / Full text
  • The effect of ladder-climbing exercise on atrophy/hypertrophy-related myokine expression in middle-aged male Wistar rats. / 11.2015 / PubMed / Full text
  • Sleep fragmentation and sepsis differentially impact blood-brain barrier integrity and transport of tumor necrosis factor-α in aging. / 11.2015 / PubMed / Full text
  • Mitochondria-targeted antioxidant SkQ1 improves impaired dermal wound healing in old mice. / 07.2015 / PubMed / Full text
  • Role of vascular peroxidase 1 in senescence of endothelial cells in diabetes rats. / 15.10.2015 / PubMed / Full text
  • [Association between carbonyl proteins and tumor necrosis factor alpha with muscle strength in young and older women: exploratory study]. / 11-12.2015 / PubMed / Full text
  • LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING. / 06.2015 / PubMed
  • Age-Dependent Alterations in the Interactions of NF-κB and N-myc with GLT-1/EAAT2 Promoter in the Pericontusional Cortex of Mice Subjected to Traumatic Brain Injury. / 07.2016 / PubMed / Full text
  • The Werner Protein Acts as a Coactivator of Nuclear Factor κB (NF-κB) on HIV-1 and Interleukin-8 (IL-8) Promoters. / 24.07.2015 / PubMed / Full text
  • Interleukin-6 as a first-rated serum inflammatory marker to predict mortality and hospitalization in the oldest old: A regression and CART approach in the BELFRAIL study. / 09.2015 / PubMed / Full text
  • Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice. / 2015 / PubMed / Full text
  • Bile acid mediated effects on gut integrity and performance of early-weaned piglets. / 14.05.2015 / PubMed / Full text
  • Increased serum levels of eotaxin/CCL11 in late-stage patients with bipolar disorder: An accelerated aging biomarker? / 15.08.2015 / PubMed / Full text
  • Vascular endothelial function is improved by oral glycine treatment in aged rats. / 06.2015 / PubMed / Full text
  • Inhibition of hedgehog signalling attenuates UVB-induced skin photoageing. / 08.2015 / PubMed / Full text
  • Age-associated modifications of intestinal permeability and innate immunity in human small intestine. / 10.2015 / PubMed / Full text
  • The stimulatory effect of the TLR4-mediated adjuvant glucopyranosyl lipid A is well preserved in old age. / 02.2016 / PubMed / Full text
  • Inhibiting tumor necrosis factor-α signaling attenuates postoperative cognitive dysfunction in aged rats. / 08.2015 / PubMed / Full text
  • Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by high-fat/high-sucrose feeding at middle age. / 06.2015 / PubMed / Full text
  • [Molecular mechanisms of combined extremely radiofrequency and infrared therapy in various age patients with chronic parodontitis]. / 2014 / PubMed
  • Exercise training increases anabolic and attenuates catabolic and apoptotic processes in aged skeletal muscle of male rats. / 07.2015 / PubMed / Full text
  • Transient early food restriction leads to hypothalamic changes in the long-lived crowded litter female mice. / 04.2015 / PubMed / Full text
  • The probiotic mixture IRT5 ameliorates age-dependent colitis in rats. / 06.2015 / PubMed / Full text
  • Essential role of POLDIP2 in Tau aggregation and neurotoxicity via autophagy/proteasome inhibition. / 26.06.2015 / PubMed / Full text
  • Inflammaging decreases adaptive and innate immune responses in mice and humans. / 02.2016 / PubMed / Full text
  • Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli. / 21.04.2015 / PubMed / Full text
  • Relationship between biomarkers of inflammation, oxidative stress and endothelial/microcirculatory function in successful aging versus healthy youth: a transversal study. / 08.04.2015 / PubMed / Full text
  • No strong correlations between serum cytokine levels, CMV serostatus and hand-grip strength in older subjects in the Berlin BASE-II cohort. / 02.2016 / PubMed / Full text
  • Fibroblast growth factor 21 protects mouse brain against D-galactose induced aging via suppression of oxidative stress response and advanced glycation end products formation. / 06.2015 / PubMed / Full text
  • The p53/miR-17/Smurf1 pathway mediates skeletal deformities in an age-related model via inhibiting the function of mesenchymal stem cells. / 03.2015 / PubMed / Full text
  • Acute exercise increases hippocampal TNF-α, Caspase-3 and Caspase-7 expression in healthy young and older mice. / 04.2015 / PubMed
  • Autophagy in axonal degeneration in glaucomatous optic neuropathy. / 07.2015 / PubMed / Full text
  • Prophylactic lithium alleviates splenectomy-induced cognitive dysfunction possibly by inhibiting hippocampal TLR4 activation in aged rats. / 05.2015 / PubMed / Full text
  • Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment. / 2015 / PubMed / Full text
  • Association of systemic inflammation with epicardial fat and coronary artery calcification. / 05.2015 / PubMed / Full text
  • Age-associated changes in granulosa cell transcript abundance in equine preovulatory follicles. / 07.2015 / PubMed / Full text
  • Effects of er-miao-san extracts on TNF-alpha-induced MMP-1 expression in human dermal fibroblasts. / 26.01.2015 / PubMed / Full text
  • Immunostimulatory effects of RACK1 pseudosubstrate in human leukocytes obtained from young and old donors. / 30.03.2015 / PubMed / Full text
  • Patient-relevant endpoints in inflammatory bowel diseases--have changes occurred in Germany over the past twelve years? / 05.2015 / PubMed / Full text
  • Anti-inflammatory effect of resveratrol in old mice liver. / 04.2015 / PubMed / Full text
  • Blockade of PD-1 or p38 MAP kinase signaling enhances senescent human CD8( ) T-cell proliferation by distinct pathways. / 05.2015 / PubMed / Full text
  • Circulating TNF and mitochondrial DNA are major determinants of neutrophil phenotype in the advanced-age, frail elderly. / 05.2015 / PubMed / Full text
  • Salidroside protects against premature senescence induced by ultraviolet B irradiation in human dermal fibroblasts. / 06.2015 / PubMed / Full text
  • Selected pro- and anti-inflammatory cytokines in cerebrospinal fluid in normal pressure hydrocephalus. / 2014 / PubMed
  • Vaginal cytokines do not correlate with postmenopausal vulvovaginal symptoms. / 04.2015 / PubMed / Full text
  • Age-related differences in polyfunctional T cell responses. / 2014 / PubMed / Full text
  • Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of D-galactose treated mice. / 02.2015 / PubMed / Full text
  • Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice. / 05.01.2015 / PubMed / Full text
  • Tumor necrosis factor-α-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo. / 01.2015 / PubMed / Full text
  • Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice. / 15.01.2015 / PubMed / Full text
  • Pre-Operative, High-IL-6 Blood Level is a Risk Factor of Post-Operative Delirium Onset in Old Patients. / 2014 / PubMed / Full text
  • Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease. / 2015 / PubMed / Full text
  • Inflammasomes in neuroinflammation and changes in brain function: a focused review. / 2014 / PubMed / Full text
  • Impact of gasless laparoscopy on circulation, respiration, stress response, and other complications in gynecological geriatrics. / 2014 / PubMed / Full text
  • Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice. / 17.11.2014 / PubMed / Full text
  • Sleep deprivation and divergent toll-like receptor-4 activation of cellular inflammation in aging. / 01.02.2015 / PubMed / Full text
  • Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging. / 11.2015 / PubMed / Full text
  • The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice. / 15.12.2014 / PubMed / Full text
  • Evidence for altered inflammatory and repair responses in symptomatic carotid plaques from elderly patients. / 11.2014 / PubMed / Full text
  • Immunosenescence in monocytes, macrophages, and dendritic cells: lessons learned from the lung and heart. / 11.2014 / PubMed / Full text
  • Ferrocifen derivatives that induce senescence in cancer cells: selected examples. / 12.2014 / PubMed / Full text
  • Role of mitochondrial reactive oxygen species in age-related inflammatory activation of endothelium. / 08.2014 / PubMed / Full text
  • Aging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery. / 2014 / PubMed / Full text
  • Simultaneous monitoring of cerebral metal accumulation in an experimental model of Wilson's disease by laser ablation inductively coupled plasma mass spectrometry. / 20.08.2014 / PubMed / Full text
  • Interleukin-1 deficiency prolongs ovarian lifespan in mice. / 26.08.2014 / PubMed / Full text
  • HIV-1 transgenic rats display alterations in immunophenotype and cellular responses associated with aging. / 2014 / PubMed / Full text
  • Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers. / 01.2015 / PubMed / Full text
  • Relationship between vitamin D and inflammatory markers in older individuals. / 2014 / PubMed / Full text
  • Association of pulse pressure with serum TNF-α and neutrophil count in the elderly. / 2014 / PubMed / Full text
  • Peritoneal exudate cells from long-lived rats exhibit increased IL-10/IL-1β expression ratio and preserved NO/urea ratio following LPS-stimulation in vitro. / 2014 / PubMed / Full text
  • Cortisol, cytokines, and hippocampal volume interactions in the elderly. / 2014 / PubMed / Full text
  • DaoTan decoction (DTD) inhibits tumor necrosis factor-α (TNF-α)-induced expression of intercellular adhesion molecule-1 (ICAM-1), p53 and p21, in human umbilical vein endothelia cells (HUVECs). / 10.2014 / PubMed / Full text
  • Improvement in Th1/Th2 immune homeostasis, antioxidative status and resistance to pathogenic E. coli on consumption of probiotic Lactobacillus rhamnosus fermented milk in aging mice. / 2014 / PubMed / Full text
  • Aging oppositely affects TNF-α and IL-10 production by macrophages from different rat strains. / 2014 / PubMed / Full text
  • Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging. / 2014 / PubMed / Full text
  • iPLA2β knockout mouse, a genetic model for progressive human motor disorders, develops age-related neuropathology. / 08.2014 / PubMed / Full text
  • Site-specific changes in cytokine response to septic dose of lipopolysaccharide in ovariectomized female rats. / 08.2014 / PubMed / Full text
  • D-galactose induced inflammation lipid peroxidation and platelet activation in rats. / 09.2014 / PubMed / Full text
  • Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity. / 05.2014 / PubMed / Full text
  • Bacteria and Toll-like receptor and cytokine mRNA expression profiles associated with canine arthritis. / 15.08.2014 / PubMed / Full text
  • Distinct age-matched serum biomarker profiles in patients with cutaneous T-cell lymphoma. / 08.2014 / PubMed / Full text
  • Age-related activation of MKK/p38/NF-κB signaling pathway in lung: from mouse to human. / 09.2014 / PubMed / Full text
  • Changes in the expression of the Toll-like receptor system in the aging rat kidneys. / 2014 / PubMed / Full text
  • Comparative analysis of low-level laser therapy (660 nm) on inflammatory biomarker expression during the skin wound-repair process in young and aged rats. / 09.2014 / PubMed / Full text
  • Inflammation and prolonged QT time: results from the Cardiovascular Disease, Living and Ageing in Halle (CARLA) study. / 2014 / PubMed / Full text
  • Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state. / 11.2014 / PubMed / Full text
  • Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals. / 08.2014 / PubMed / Full text
  • Maturation of innate responses to mycobacteria over the first nine months of life. / 15.05.2014 / PubMed / Full text
  • Effects of age and macrophage lineage on intracellular survival and cytokine induction after infection with Rhodococcus equi. / 15.07.2014 / PubMed / Full text
  • IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice. / 06.2014 / PubMed / Full text
  • A comparison of pro-inflammatory cytokine mRNA expression in equine bronchoalveolar lavage (BAL) and peripheral blood. / 15.04.2014 / PubMed / Full text
  • Moderate swimming exercise and caffeine supplementation reduce the levels of inflammatory cytokines without causing oxidative stress in tissues of middle-aged rats. / 05.2014 / PubMed / Full text
  • Effects of aging on influenza virus infection dynamics. / 04.2014 / PubMed / Full text
  • Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for "inflamm-aging". / 05.2014 / PubMed / Full text
  • Markers of low-grade inflammation and endothelial dysfunction are related to reduced information processing speed and executive functioning in an older population - the Hoorn Study. / 02.2014 / PubMed / Full text
  • Bacopa monnieri (L.) exerts anti-inflammatory effects on cells of the innate immune system in vitro. / 03.2014 / PubMed / Full text
  • Resveratrol increases antioxidant defenses and decreases proinflammatory cytokines in hippocampal astrocyte cultures from newborn, adult and aged Wistar rats. / 06.2014 / PubMed / Full text
  • High TNF-α levels in resting B cells negatively correlate with their response. / 06.2014 / PubMed / Full text
  • Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life. / 06.2014 / PubMed / Full text
  • Deleterious effects of aggressive rapid crystalloid resuscitation on treatment of hyperinflammatory response and lung injury induced by hemorrhage in aging rats. / 04.2014 / PubMed / Full text
  • Soluble tumor necrosis factor receptors and heart failure risk in older adults: Health, Aging, and Body Composition (Health ABC) Study. / 01.2014 / PubMed / Full text
  • Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size. / 11-12.2013 / PubMed / Full text
  • Study of antitumor activity of antibodies to TNF-α on Walker carcinosarcoma model. / 09.2013 / PubMed / Full text
  • Voluntary wheel running does not affect lipopolysaccharide-induced depressive-like behavior in young adult and aged mice. / 2014 / PubMed / Full text
  • Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis. / 01.2014 / PubMed / Full text
  • Chronic alcohol consumption disrupts myocardial protein balance and function in aged, but not adult, female F344 rats. / 01.01.2014 / PubMed / Full text
  • Association among 1267 A/G HSP70-2, -308 G/A TNF-α polymorphisms and pro-inflammatory plasma mediators in old ZincAge population. / 02.2014 / PubMed / Full text
  • Diabetes, depressive symptoms, and inflammation in older adults: results from the Health, Aging, and Body Composition Study. / 11.2013 / PubMed / Full text
  • Age effects on mouse and human B cells. / 12.2013 / PubMed / Full text
  • Limited utility of adipokine levels in the diagnosis of malnutrition in the elderly. / 04.2014 / PubMed / Full text
  • Systemic inflammatory responses and lung injury following hip fracture surgery increases susceptibility to infection in aged rats. / 2013 / PubMed / Full text
  • Analysis of cognition, motor performance and anxiety in young and aged tumor necrosis factor alpha receptor 1 and 2 deficient mice. / 01.01.2014 / PubMed / Full text
  • Hip fracture aggravates systemic inflammation and lung injury in aged chronic cigarette smoke exposed rats. / 01.2014 / PubMed / Full text
  • Probiotic modulation of dendritic cell function is influenced by ageing. / 02.2014 / PubMed / Full text
  • Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy. / 21.10.2013 / PubMed / Full text
  • Association of inflammation with loss of ability to walk 400 meters: longitudinal findings from the Invecchiare in Chianti Study. / 10.2013 / PubMed / Full text
  • Elevated COX2 expression and PGE2 production by downregulation of RXRα in senescent macrophages. / 11.10.2013 / PubMed / Full text
  • Tumor necrosis factor-α inhibition improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women. / 10.2013 / PubMed / Full text
  • Effects of ethanol on immune response in the brain: region-specific changes in adolescent versus adult mice. / 02.2014 / PubMed / Full text
  • Aging enhances release of exosomal cytokine mRNAs by Aβ1-42-stimulated macrophages. / 12.2013 / PubMed / Full text
  • Dendritic cells from the elderly display an intrinsic defect in the production of IL-10 in response to lithium chloride. / 11.2013 / PubMed / Full text
  • Longitudinal analysis of short-term high-fat diet on endothelial senescence in baboons. / 2013 / PubMed / Full text
  • Combined administration of oseltamivir and hochu-ekki-to (TJ-41) dramatically decreases the viral load in lungs of senescence-accelerated mice during influenza virus infection. / 02.2014 / PubMed / Full text
  • ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis. / 08.2014 / PubMed / Full text
  • Concentrated fish oil (Lovaza(R)) extends lifespan and attenuates kidney disease in lupus-prone short-lived (NZBxNZW)F1 mice. / 06.2013 / PubMed / Full text
  • Soluble ecto-5'-nucleotidase (5'-NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine. / 20.09.2013 / PubMed / Full text
  • Aging affects AO rat splenic conventional dendritic cell subset composition, cytokine synthesis and T-helper polarizing capacity. / 08.2013 / PubMed / Full text
  • Senescent endothelial cells are prone to TNF-α-induced cell death due to expression of FAS receptor. / 23.08.2013 / PubMed / Full text
  • Age-related CD4( )CD25( )Foxp3( ) regulatory T-cell responses during Plasmodium berghei ANKA infection in mice susceptible or resistant to cerebral malaria. / 06.2013 / PubMed / Full text
  • [The relationship between the polymorphism of immunity genes and both aging and age-related diseases]. / 07.2013 / PubMed / Full text
  • The influence of aging and estradiol to progesterone ratio on rat macrophage phenotypic profile and NO and TNF-α production. / 11.2013 / PubMed / Full text
  • Proinflammatory cytokines, aging, and age-related diseases. / 12.2013 / PubMed / Full text
  • Brief report: deficient thymic output in rheumatoid arthritis despite abundance of prethymic progenitors. / 10.2013 / PubMed / Full text
  • Chronic low dose tumor necrosis factor-α (TNF) suppresses early bone accrual in young mice by inhibiting osteoblasts without affecting osteoclasts. / 09.2013 / PubMed / Full text
  • Calcium dysregulation and neuroinflammation: discrete and integrated mechanisms for age-related synaptic dysfunction. / 09.2013 / PubMed / Full text
  • Expression of angiotensin II and its receptors in activated microglia in experimentally induced cerebral ischemia in the adult rats. / 10.2013 / PubMed / Full text
  • Aging and airway inflammation. / 06.2013 / PubMed / Full text
  • A Jerte valley cherry product provides beneficial effects on sleep quality. Influence on aging. / 2013 / PubMed / Full text
  • Effects of ethanol on immune response in the brain: region-specific changes in aged mice. / 23.05.2013 / PubMed / Full text
  • Heightened muscle inflammation susceptibility may impair regenerative capacity in aging humans. / 09.2013 / PubMed / Full text
  • Angiopoietin-like 2 promotes atherogenesis in mice. / 10.05.2013 / PubMed / Full text
  • The functional tumor necrosis factor-α (308A/G) polymorphism modulates attentional selection in elderly individuals. / 11.2013 / PubMed / Full text
  • Parasitological and immunological aspects of early Ascaris spp. infection in mice. / 08.2013 / PubMed / Full text
  • Neurogenic factor-induced Langerhans cell activation in diabetic mice with mechanical allodynia. / 14.05.2013 / PubMed / Full text
  • The roles of immune memory and aging in protective immunity and endogenous reactivation of tuberculosis. / 2013 / PubMed / Full text
  • Chronic neuron- and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid- and Tau-related pathologies. / 06.2013 / PubMed / Full text
  • Ageing impairs the T cell response to dendritic cells. / 08.2013 / PubMed / Full text
  • Aging accentuates alcohol-induced decrease in protein synthesis in gastrocnemius. / 15.05.2013 / PubMed / Full text
  • Propolis efficacy on TNF-α, IFN-γ and IL2 cytokines production in old mice with and without systemic candidiasis. / 09.2012 / PubMed / Full text
  • Active muscle regeneration following eccentric contraction-induced injury is similar between healthy young and older adults. / 01.06.2014 / PubMed / Full text
  • Maternal immune activation leads to age-related behavioral and immunological changes in male rat offspring - the effect of antipsychotic drugs. / 2012 / PubMed / Full text
  • TNF-α, IL6, and IL10 polymorphisms and the effect of physical exercise on inflammatory parameters and physical performance in elderly women. / 12.2013 / PubMed / Full text
  • Blood CD33( )HLA-DR(-) myeloid-derived suppressor cells are increased with age and a history of cancer. / 04.2013 / PubMed / Full text
  • Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE study. / 03.2013 / PubMed / Full text
  • Maintenance of CMV-specific CD8 T cell responses and the relationship of IL-27 to IFN-γ levels with aging. / 02.2013 / PubMed / Full text
  • Minocycline mitigates isoflurane-induced cognitive impairment in aged rats. / 16.02.2013 / PubMed / Full text
  • Relationships between body condition score and plasma inflammatory cytokines, insulin, and lipids in a mixed population of light-breed horses. / 01-02.2013 / PubMed / Full text
  • Age-related changes in intracellular expression of IFN-γ and TNF-α in equine lymphocytes measured in bronchoalveolar lavage and peripheral blood. / 03.2013 / PubMed / Full text

SIRT1[править]

  • SIRT1 - a new mammalian substrate of nuclear autophagy. / 08.12.2020 / PubMed / Full text
  • The Aging Stress Response and Its Implication for AMD Pathogenesis. / 22.11.2020 / PubMed / Full text
  • Anthocyanins attenuate endothelial dysfunction through regulation of uncoupling of nitric oxide synthase in aged rats. / 03.12.2020 / PubMed / Full text
  • Sirtuins and Their Implications in Neurodegenerative Diseases from a Drug Discovery Perspective. / 05.12.2020 / PubMed / Full text
  • Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe mice: role of SIRT1. / 18.11.2020 / PubMed / Full text
  • Effects of alpha-mangostin on memory senescence induced by high glucose in human umbilical vein endothelial cells. / 10.2020 / PubMed / Full text
  • Melatonin and Sirtuins in Buccal Epithelium: Potential Biomarkers of Aging and Age-Related Pathologies. / 30.10.2020 / PubMed / Full text
  • SIRT1 Activation Using CRISPR/dCas9 Promotes Regeneration of Human Corneal Endothelial Cells through Inhibiting Senescence. / 04.11.2020 / PubMed / Full text
  • Histone Deacetylase SIRT1, Smooth Muscle Cell Function, and Vascular Diseases. / 2020 / PubMed / Full text
  • 6,4'-dihydroxy-7-methoxyflavanone protects against H O -induced cellular senescence by inducing SIRT1 and inhibiting phosphatidylinositol 3-kinase/Akt pathway activation. / 27.10.2020 / PubMed / Full text
  • Sirtuins as Possible Predictors of Aging and Alzheimer's Disease Development: Verification in the Hippocampus and Saliva. / 10.2020 / PubMed / Full text
  • FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. / 14.10.2020 / PubMed / Full text
  • A comparative study on the cellular stressors in mesenchymal stem cells (MSCs) and pancreatic β-cells under hyperglycemic milieu. / 30.09.2020 / PubMed / Full text
  • [i]Citrus hystrix[/i] Extracts Protect Human Neuronal Cells against High Glucose-Induced Senescence. / 30.09.2020 / PubMed / Full text
  • Isoparvifuran isolated from Dalbergia odorifera attenuates H O -induced senescence of BJ cells through SIRT1 activation and AKT/mTOR pathway inhibition. / 30.09.2020 / PubMed / Full text
  • SIRT1 Is the Target Gene for 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside Alleviating the HUVEC Senescence. / 2020 / PubMed / Full text
  • Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction. / 02.11.2020 / PubMed / Full text
  • The Role of Sirtuins in Kidney Diseases. / 12.09.2020 / PubMed / Full text
  • The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men. / 11.2020 / PubMed / Full text
  • Senescence and autophagy in usual interstitial pneumonia of different etiology. / 27.08.2020 / PubMed / Full text
  • Virus-Induced Asthma Exacerbations: SIRT1 Targeted Approach. / 13.08.2020 / PubMed / Full text
  • Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts. / 12.2020 / PubMed / Full text
  • Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/SIRT1-FOXA3-Beclin1 pathway. / 01.10.2020 / PubMed / Full text
  • Ginsenoside Rg1 protects against Sca-1 HSC/HPC cell aging by regulating the SIRT1-FOXO3 and SIRT3-SOD2 signaling pathways in a γ-ray irradiation-induced aging mice model. / 08.2020 / PubMed / Full text
  • Therapeutic Effects of SRT2104 on Lung Injury in Rats with Emphysema via Reduction of Type II Alveolar Epithelial Cell Senescence. / 08.2020 / PubMed / Full text
  • Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis. / 15.09.2020 / PubMed / Full text
  • SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy. / 18.07.2020 / PubMed / Full text
  • Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects. / 09.2020 / PubMed / Full text
  • Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence. / 10.2020 / PubMed / Full text
  • Inhibition of miR-34a reduces cellular senescence in human adipose tissue-derived mesenchymal stem cells through the activation of SIRT1. / 15.09.2020 / PubMed / Full text
  • Transcriptome analysis of common and diverged circulating miRNAs between arterial and venous during aging. / 30.06.2020 / PubMed / Full text
  • Activation of FoxO1/SIRT1/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis. / 12.06.2020 / PubMed / Full text
  • Latifolin Inhibits Oxidative Stress-Induced Senescence via Upregulation of SIRT1 in Human Dermal Fibroblasts. / 01.07.2020 / PubMed / Full text
  • Metabolite Profiling of Rambutan ([i]Nephelium lappaceum[/i] L.) Seeds Using UPLC-qTOF-MS/MS and Senomorphic Effects in Aged Human Dermal Fibroblasts. / 15.05.2020 / PubMed / Full text
  • SRT1720-induced activation of SIRT1 alleviates vascular smooth muscle cell senescence through PKA-dependent phosphorylation of AMPKα at Ser485. / 07.2020 / PubMed / Full text
  • Circadian rhythm disruption and Alzheimer's disease: The dynamics of a vicious cycle. / 28.04.2020 / PubMed / Full text
  • miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss. / 2020 / PubMed / Full text
  • Lymphocyte senescence in COPD is associated with decreased sirtuin 1 expression in steroid resistant pro-inflammatory lymphocytes. / 01-12.2020 / PubMed / Full text
  • Therapeutic effects of hydro-alcoholic leaf extract of Withania somnifera on age-induced changes in daily rhythms of Sirt1, Nrf2 and Rev-erbα in the SCN of male Wistar rats. / 10.2020 / PubMed / Full text
  • Dipeptidyl peptidase-4 inhibition improves endothelial senescence by activating AMPK/SIRT1/Nrf2 signaling pathway. / 07.2020 / PubMed / Full text
  • The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis. / 2020 / PubMed / Full text
  • Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells. / 2020 / PubMed / Full text
  • Spatiotemporal gating of SIRT1 functions by O-GlcNAcylation is essential for liver metabolic switching and prevents hyperglycemia. / 24.03.2020 / PubMed / Full text
  • Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of SIRT1. / 2020 / PubMed / Full text
  • SIRT1 and aging related signaling pathways. / 04.2020 / PubMed / Full text
  • Tropisetron protects against brain aging via attenuating oxidative stress, apoptosis and inflammation: The role of SIRT1 signaling. / 01.05.2020 / PubMed / Full text
  • Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. / 04.2020 / PubMed / Full text
  • The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1. / 2020 / PubMed / Full text
  • Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells. / 01.05.2020 / PubMed / Full text
  • Chronic Polyphenon-60 or Catechin Treatments Increase Brain Monoamines Syntheses and Hippocampal SIRT1 Levels Improving Cognition in Aged Rats. / 26.01.2020 / PubMed / Full text
  • Context-Dependent Roles for SIRT2 and SIRT3 in Tumor Development Upon Calorie Restriction or High Fat Diet. / 2019 / PubMed / Full text
  • Duck Oil-loaded Nanoemulsion Inhibits Senescence of Angiotensin II-treated Vascular Smooth Muscle Cells by Upregulating SIRT1. / 01.2020 / PubMed / Full text
  • Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence. / 06-07.2020 / PubMed / Full text
  • Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1. / 23.12.2019 / PubMed / Full text
  • The protective role of omentin-1 in IL-1β-induced chondrocyte senescence. / 12.2020 / PubMed / Full text
  • The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD Level Is Lower than the Sirtuin-Saturating Concentrations. / 24.12.2019 / PubMed / Full text
  • Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells. / 06.2020 / PubMed / Full text
  • Central nervous system SIRT1 expression is required for cued and contextual fear conditioning memory responses in aging mice. / 23.09.2019 / PubMed / Full text
  • Does education level protect us from rapid ageing? Sirtuin expression versus age and level of education. / 10.2019 / PubMed
  • CO ameliorates endothelial senescence induced by 5-fluorouracil through SIRT1 activation. / 30.11.2019 / PubMed / Full text
  • Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating SIRT1 expression. / 20.10.2019 / PubMed / Full text
  • NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice. / 01.2020 / PubMed / Full text
  • The Role of Sirtuin1 in Regulating Endothelial Function, Arterial Remodeling and Vascular Aging. / 2019 / PubMed / Full text
  • Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. / 03.2020 / PubMed / Full text
  • Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure. / 13.02.2020 / PubMed / Full text
  • Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD). / 11.09.2019 / PubMed / Full text
  • Hydrogen Sulfide Inhibits High Glucose-Induced Neuronal Senescence by Improving Autophagic Flux [i]via[/i] Up-regulation of SIRT1. / 2019 / PubMed / Full text
  • MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities. / 22.08.2019 / PubMed / Full text
  • Activation of the miR-34a-Mediated SIRT1/mTOR Signaling Pathway by Urolithin A Attenuates D-Galactose-Induced Brain Aging in Mice. / 10.2019 / PubMed / Full text
  • [Ginsenoside Rg_1 induces leukemia stem cell senescence via SIRT1/TSC_2 signal axis]. / 06.2019 / PubMed / Full text
  • miR-23b-3p regulates apoptosis and autophagy via suppressing SIRT1 in lens epithelial cells. / 12.2019 / PubMed / Full text
  • Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
  • Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity. / 08.2019 / PubMed / Full text
  • Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence. / 01.10.2019 / PubMed / Full text
  • Involvement of [i]microRNA-34a[/i] in Age-Related Susceptibility to Oxidative Stress in ARPE-19 Cells by Targeting the Silent Mating Type Information Regulation 2 Homolog 1/p66shc Pathway: Implications for Age-Related Macular Degeneration. / 2019 / PubMed / Full text
  • GPR39 agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence. / 12.2019 / PubMed / Full text
  • Rational design of novel sirtuin 1 activators via structure-activity insights from application of QSAR modeling. / 2019 / PubMed / Full text
  • Metformin prevents murine ovarian aging. / 10.06.2019 / PubMed / Full text
  • Time-restricted feeding delays the emergence of the age-associated, neoplastic-prone tissue landscape. / 12.06.2019 / PubMed / Full text
  • Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway. / 10.06.2019 / PubMed / Full text
  • SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy. / 08.2019 / PubMed / Full text
  • Transcriptome analysis revealed potential mechanisms of differences in physiological stress responses between caged male and female magpies. / 03.06.2019 / PubMed / Full text
  • Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. / 10.2019 / PubMed / Full text
  • Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models. / 02.2019 / PubMed / Full text
  • Molecular and Cellular Characterization of SIRT1 Allosteric Activators. / 2019 / PubMed / Full text
  • Total flavonoids from the Carya cathayensis Sarg. leaves inhibit HUVEC senescence through the miR-34a/SIRT1 pathway. / 10.2019 / PubMed / Full text
  • Impaired SIRT1 activity leads to diminution in glomerular endowment without accelerating age-associated GFR decline. / 05.2019 / PubMed / Full text
  • Estrogen-SIRT1 Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis. / 01.01.2020 / PubMed / Full text
  • Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri. / 09.2019 / PubMed / Full text
  • Protective effect of vildagliptin on TNF-α-induced chondrocyte senescence. / 07.2019 / PubMed / Full text
  • Polymorphism rs7895833 in the SIRT1 gene and its association with dyslipidaemia in the elderly. / 07-08.2019 / PubMed / Full text
  • Modulation of miR-34a/SIRT1 signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis. / 07.2019 / PubMed / Full text
  • Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow. / 18.04.2019 / PubMed / Full text
  • Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom [i]Cordyceps militaris[/i] Linn., Ameliorates Age-Related Testicular Dysfunction in Rats. / 23.04.2019 / PubMed / Full text
  • The resistant effect of SIRT1 in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway. / 31.05.2019 / PubMed / Full text
  • Photobiomodulation and Coenzyme Q Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice. / 2019 / PubMed / Full text
  • The role of SIRT1 in neuroinflammation and cognitive dysfunction in aged rats after anesthesia and surgery. / 2019 / PubMed / Full text
  • NAD supplementation rejuvenates aged gut adult stem cells. / 06.2019 / PubMed / Full text
  • NMNAT2-mediated NAD generation is essential for quality control of aged oocytes. / 06.2019 / PubMed / Full text
  • Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure. / 07.2019 / PubMed / Full text
  • Drugs targeting SIRT1, a new generation of therapeutics for osteoporosis and other bone related disorders? / 05.2019 / PubMed / Full text
  • Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks. / 11.03.2019 / PubMed / Full text
  • Knockout of receptor for advanced glycation end-products attenuates age-related renal lesions. / 04.2019 / PubMed / Full text
  • Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson's disease. / 04.02.2019 / PubMed / Full text
  • Bone Marrow Mesenchymal Stem Cells-Derived Exosomal MiR-29b-3p Regulates Aging-Associated Insulin Resistance. / 26.02.2019 / PubMed / Full text
  • Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats. / 02.2019 / PubMed / Full text
  • Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease. / 05.2019 / PubMed / Full text
  • Generation of a novel model of primary human cell senescence through Tenovin-6 mediated inhibition of sirtuins. / 06.2019 / PubMed / Full text
  • Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. / 04.2019 / PubMed / Full text
  • Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanism. / 23.01.2019 / PubMed / Full text
  • Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation. / 2018 / PubMed / Full text
  • NKT-like cells reveal higher than T lymphocytes expression of cellular protective proteins HSP70 and SOD2 and comparably increased expression of SIRT1 in the oldest seniors. / 2018 / PubMed / Full text
  • Melatonin regulates the activities of ovary and delays the fertility decline in female animals via MT1/AMPK pathway. / 04.2019 / PubMed / Full text
  • Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats. / 23.12.2018 / PubMed / Full text
  • Establishment of a Mouse Model of Premature Ovarian Failure Using Consecutive Superovulation. / 2018 / PubMed / Full text
  • Diesel exhaust exposure intensifies inflammatory and structural changes associated with lung aging in mice. / 15.04.2019 / PubMed / Full text
  • CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2. / 2018 / PubMed / Full text
  • Amentoflavone Induces Autophagy and Modulates p53. / 04.2019 / PubMed / Full text
  • Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells. / 03.2019 / PubMed / Full text
  • Sirtuins: Developing Innovative Treatments for Aged-Related Memory Loss and Alzheimer's Disease. / 2018 / PubMed / Full text
  • N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation. / 01.2019 / PubMed / Full text
  • Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice. / 20.11.2018 / PubMed / Full text
  • Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation. / 2018 / PubMed / Full text
  • Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and [i]C. elegans[/i]. / 20.11.2018 / PubMed / Full text
  • Sirtuins and NAD in the Development and Treatment of Metabolic and Cardiovascular Diseases. / 14.09.2018 / PubMed / Full text
  • SIRT1 deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis. / 12.2018 / PubMed / Full text
  • Prevention of Senescence in Vasculature Through Quiescence. / 10.2018 / PubMed / Full text
  • Melatonin and inflammation-Story of a double-edged blade. / 11.2018 / PubMed / Full text
  • ALDH2 mediates the dose-response protection of chronic ethanol against endothelial senescence through SIRT1/p53 pathway. / 12.10.2018 / PubMed / Full text
  • Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats. / 08.2018 / PubMed / Full text
  • Endothelial SIRT1 prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle cells. / 01.03.2019 / PubMed / Full text
  • Effects of Ginsenoside Rg3 on fatigue resistance and SIRT1 in aged rats. / 01.11.2018 / PubMed / Full text
  • PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD levels and increasing SIRT1 activity. / 23.08.2018 / PubMed / Full text
  • Moderate calorie restriction attenuates age‑associated alterations and improves cardiac function by increasing SIRT1 and SIRT3 expression. / 10.2018 / PubMed / Full text
  • Liver regeneration in aged mice: new insights. / 28.08.2018 / PubMed / Full text
  • Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit's Heart and Liver. / 2018 / PubMed / Full text
  • Defect of SIRT1-FoxO3a axis is associated with the production of reactive oxygen species during protein kinase CK2 downregulation-mediated cellular senescence and nematode aging. / 04.2019 / PubMed / Full text
  • Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls. / 10.2018 / PubMed / Full text
  • Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes. / 01.05.2019 / PubMed / Full text
  • PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis. / 07.08.2018 / PubMed / Full text
  • Effect of oral appliance on circulating leukocyte telomere length and SIRT1 in obstructive sleep apnea. / 03.2019 / PubMed / Full text
  • miR-34a Promotes Vascular Smooth Muscle Cell Calcification by Downregulating SIRT1 (Sirtuin 1) and Axl (AXL Receptor Tyrosine Kinase). / 09.2018 / PubMed / Full text
  • A SIRT1-centered circuitry regulates breast cancer stemness and metastasis. / 12.2018 / PubMed / Full text
  • Apelin/APJ axis improves angiotensin II-induced endothelial cell senescence through AMPK/SIRT1 signaling pathway. / 06.2018 / PubMed / Full text
  • Sirtuin 1 and Alzheimer's disease: An up-to-date review. / 10.2018 / PubMed / Full text
  • CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans. / 10.2018 / PubMed / Full text
  • Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-SIRT1-eNOS pathway. / 09.2018 / PubMed / Full text
  • Serum containing Buyang Huanwu decoction prevents age-associated migration and invasion of human vascular smooth muscle cells by up regulating SIRT1 expression. / 17.07.2018 / PubMed / Full text
  • Role of accelerated aging in limb muscle wasting of patients with COPD. / 2018 / PubMed / Full text
  • Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells. / 15.09.2018 / PubMed / Full text
  • Mesenchymal stem cells confer resistance to doxorubicin-induced cardiac senescence by inhibiting microRNA-34a. / 06.2018 / PubMed / Full text
  • The circadian clock in adult neural stem cell maintenance. / 02.2019 / PubMed / Full text
  • Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri. / 09.2018 / PubMed / Full text
  • Loss of NAMPT in aging retinal pigment epithelium reduces NAD availability and promotes cellular senescence. / 12.06.2018 / PubMed / Full text
  • Mushroom extract inhibits ultraviolet B-induced cellular senescence in human keratinocytes. / 06.2018 / PubMed / Full text
  • SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease. / 31.05.2018 / PubMed / Full text
  • Endothelial progenitor cells from aged subjects display decreased expression of sirtuin 1, angiogenic functions, and increased senescence. / 09.2018 / PubMed / Full text
  • Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial Function. / 09.2018 / PubMed / Full text
  • Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats. / 2018 / PubMed / Full text
  • SIRT1 reverses senescence via enhancing autophagy and attenuates oxidative stress-induced apoptosis through promoting p53 degradation. / 01.10.2018 / PubMed / Full text
  • Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers. / 08.2018 / PubMed / Full text
  • Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition. / 07.2018 / PubMed / Full text
  • Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of SIRT1. / 2017 / PubMed / Full text
  • Role of hypothalamus in aging and its underlying cellular mechanisms. / 01.2019 / PubMed / Full text
  • The variable role of SIRT1 in the maintenance and differentiation of mesenchymal stem cells. / 04.2018 / PubMed / Full text
  • Sirtuins in Renal Health and Disease. / 07.2018 / PubMed / Full text
  • Physical Exercise Improves Aging-Related Changes in Angiotensin, IGF-1, SIRT1, SIRT3, and VEGF in the Substantia Nigra. / 10.11.2018 / PubMed / Full text
  • MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells. / 03.04.2018 / PubMed / Full text
  • Natural products with anti-aging potential: Affected targets and molecular mechanisms. / 01.11.2018 / PubMed / Full text
  • [Effect of microRNA-34a/SIRT1/p53 signal pathway on notoginsenoside R₁ delaying vascular endothelial cell senescence]. / 02.2018 / PubMed / Full text
  • SIRT1 and microRNAs: The role in breast, lung and prostate cancers. / 01.06.2018 / PubMed / Full text
  • Leukotriene D4 induces cellular senescence in osteoblasts. / 05.2018 / PubMed / Full text
  • Impairment of an Endothelial NAD -H S Signaling Network Is a Reversible Cause of Vascular Aging. / 22.03.2018 / PubMed / Full text
  • Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas. / 08.2018 / PubMed / Full text
  • Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice. / 06.03.2018 / PubMed / Full text
  • Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming. / 05.2018 / PubMed / Full text
  • HGF and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the SIRT1/FOXO1 Signaling Pathway. / 2018 / PubMed / Full text
  • The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system. / 03.2018 / PubMed / Full text
  • Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. / 04.2018 / PubMed / Full text
  • Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes. / 03.2018 / PubMed / Full text
  • Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress. / 20.02.2018 / PubMed / Full text
  • Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury. / 11.01.2018 / PubMed / Full text
  • Acetylshikonin from Zicao attenuates cognitive impairment and hippocampus senescence in d-galactose-induced aging mouse model via upregulating the expression of SIRT1. / 03.2018 / PubMed / Full text
  • Dexamethasone downregulates SIRT1 and IL6 and upregulates EDN1 genes in stem cells derived from gingivae via the AGE/RAGE pathway. / 03.2018 / PubMed / Full text
  • Sirtuins in Brain Aging and Neurological Disorders. / 2017 / PubMed / Full text
  • [Aging-related change of erectile function and the expression of SIRT1]. / 12.2016 / PubMed
  • Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans. / 2017 / PubMed / Full text
  • Maternal aging affects oocyte resilience to carbonyl cyanide-m-chlorophenylhydrazone -induced mitochondrial dysfunction in cows. / 2017 / PubMed / Full text
  • Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating SIRT1 activity and antioxidant gene expression in mouse cells. / 12.2017 / PubMed / Full text
  • Stem Cells and Progenitors in Human Peripheral Blood Get Activated by Extremely Active Resveratrol (XAR™). / 04.2018 / PubMed / Full text
  • Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H O -induced premature senescence through SIRT1. / 2017 / PubMed / Full text
  • Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating SIRT1-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation. / 14.11.2017 / PubMed / Full text
  • Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice. / 13.10.2017 / PubMed / Full text
  • O-GlcNAcylation of SIRT1 enhances its deacetylase activity and promotes cytoprotection under stress. / 14.11.2017 / PubMed / Full text
  • Aging as an Epigenetic Phenomenon. / 10.2017 / PubMed / Full text
  • MeCP2 mediated dysfunction in senescent EPCs. / 03.10.2017 / PubMed / Full text
  • Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress. / 01.2018 / PubMed / Full text
  • A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction. / 12.09.2017 / PubMed / Full text
  • Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence. / 17.10.2017 / PubMed / Full text
  • Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts. / 28.12.2017 / PubMed / Full text
  • Blocking SIRT1 inhibits cell proliferation and promotes aging through the PI3K/AKT pathway. / 01.12.2017 / PubMed / Full text
  • SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis. / 2017 / PubMed / Full text
  • [Protective effect of total saponins of Panax notoginseng combined with total flavonoids of epimedium on D-galactose-incuced senescence of H9c2 cell]. / 02.2017 / PubMed / Full text
  • SIRT1 is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity. / 05.02.2018 / PubMed / Full text
  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
  • The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway. / 11.2017 / PubMed / Full text
  • Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats. / 03.2018 / PubMed / Full text
  • Aquatide Activation of SIRT1 Reduces Cellular Senescence through a SIRT1-FOXO1-Autophagy Axis. / 01.09.2017 / PubMed / Full text
  • Obesity and aging diminish sirtuin 1 (SIRT1)-mediated deacetylation of SIRT3, leading to hyperacetylation and decreased activity and stability of SIRT3. / 20.10.2017 / PubMed / Full text
  • Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging. / 10.08.2017 / PubMed / Full text
  • High glucose and free fatty acids induce endothelial progenitor cell senescence via PGC-1α/SIRT1 signaling pathway. / 10.2017 / PubMed / Full text
  • Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. / 2017 / PubMed / Full text
  • Comparing the Effects of Melatonin with Caloric Restriction in the Hippocampus of Aging Mice: Involvement of Sirtuin1 and the FOXOs Pathway. / 01.2018 / PubMed / Full text
  • Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression. / 2017 / PubMed / Full text
  • Inflammation, Stem Cells, and the Aging Hypothalamus. / 08.2017 / PubMed / Full text
  • Myricetin improves endurance capacity and mitochondrial density by activating SIRT1 and PGC-1α. / 24.07.2017 / PubMed / Full text
  • Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer. / 2017 / PubMed / Full text
  • The emerging role of alternative splicing in senescence and aging. / 10.2017 / PubMed / Full text
  • miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans. / 08.2017 / PubMed / Full text
  • Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells. / 01.2018 / PubMed / Full text
  • SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection. / 10.03.2018 / PubMed / Full text
  • Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging. / 30.01.2018 / PubMed / Full text
  • Reduction in podocyte SIRT1 accelerates kidney injury in aging mice. / 01.09.2017 / PubMed / Full text
  • Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs. / 12.06.2017 / PubMed / Full text
  • Ursolic Acid Mediates Hepatic Protection through Enhancing of anti-aging Biomarkers. / 2018 / PubMed / Full text
  • The NAD /PARP1/SIRT1 Axis in Aging. / 06.2017 / PubMed / Full text
  • Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota. / 09.2017 / PubMed / Full text
  • Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-SIRT1 pathway. / 08.2017 / PubMed / Full text
  • Bushen-Yizhi formula ameliorates cognitive dysfunction through SIRT1/ER stress pathway in SAMP8 mice. / 25.07.2017 / PubMed / Full text
  • Caveolin-1 deficiency induces premature senescence with mitochondrial dysfunction. / 08.2017 / PubMed / Full text
  • Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-FOXO1 pathway. / 2017 / PubMed / Full text
  • Steroidogenesis decline accompanied with reduced antioxidation and endoplasmic reticulum stress in mice testes during ageing. / 02.2018 / PubMed / Full text
  • Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats. / 08.2017 / PubMed / Full text
  • Caloric restriction delays early phases of carcinogenesis via effects on the tissue microenvironment. / 30.05.2017 / PubMed / Full text
  • During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent. / 08.2017 / PubMed / Full text
  • Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. / 01.06.2017 / PubMed / Full text
  • Regulation of stem cell aging by SIRT1 - Linking metabolic signaling to epigenetic modifications. / 05.11.2017 / PubMed / Full text
  • Ampelopsin attenuates the atrophy of skeletal muscle from d-gal-induced aging rats through activating AMPK/SIRT1/PGC-1α signaling cascade. / 06.2017 / PubMed / Full text
  • SIRT1 Polymorphisms and Serum-Induced SIRT1 Protein Expression in Aging and Frailty: The CHAMP Study. / 01.07.2017 / PubMed / Full text
  • Melatonin reverses H O -induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB. / 08.2017 / PubMed / Full text
  • Alkylresorcinols activate SIRT1 and delay ageing in Drosophila melanogaster. / 02.03.2017 / PubMed / Full text
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|title=Tat-Mediated Induction of miRs-34a