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Редактирование:
Aging genes 30-59
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==IVD== * {{medline-title |title=MicroRNAs in Intervertebral Disc Degeneration, Apoptosis, Inflammation, and Mechanobiology. |date=20.05.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32443722 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279351 }} * {{medline-title |title=A step-by-step protocol for isolation of murine nucleus pulposus cells. |date=12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31891122 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920701 }} * {{medline-title |title=Caspase-3 knockout inhibits intervertebral disc degeneration related to injury but accelerates degeneration related to aging. |date=18.12.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31852919 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920379 }} * {{medline-title |title=Finite element and deformation analyses predict pattern of bone failure in loaded zebrafish spines. |date=29.11.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31690186 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893493 }} * {{medline-title |title=Improvement in determining the risk of damage to the human lumbar functional spinal unit considering age, height, weight and sex using a combination of FEM and RSM. |date=02.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31473842 |full-text-url=https://sci-hub.do/10.1007/s10237-019-01215-4 }} * {{medline-title |title=In vivo contrast-enhanced microCT for the monitoring of mouse thoracic, lumbar, and coccygeal intervertebral discs. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31463468 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686789 }} * {{medline-title |title=MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway. |date=15.04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30987676 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769 }} * {{medline-title |title=Curcumin and o-Vanillin Exhibit Evidence of Senolytic Activity in Human [[IVD]] Cells In Vitro. |date=29.03.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30934902 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518239 }} * {{medline-title |title=Aging of mouse intervertebral disc and association with back pain. |date=06.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30936040 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549718 }} * {{medline-title |title=Role of heparan sulfate 6-0 endosulfatases in intervertebral disc homeostasis. |date=09.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30924907 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742574 }} * {{medline-title |title=Evaluation of age-related changes in lumbar facet joints using T2 mapping. |date=01.2020 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890294 |full-text-url=https://sci-hub.do/10.1016/j.jos.2019.02.017 }} * {{medline-title |title=A histocytological and radiological overview of the natural history of intervertebral disk: from embryonic formation to age-related degeneration. |date=04.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30715648 |full-text-url=https://sci-hub.do/10.1007/s00586-019-05903-8 }} * {{medline-title |title=Regenerative potential of human nucleus pulposus resident stem/progenitor cells declines with ageing and intervertebral disc degeneration. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30015833 |full-text-url=https://sci-hub.do/10.3892/ijmm.2018.3766 }} * {{medline-title |title=[[TRPC6]] in simulated microgravity of intervertebral disc cells. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29968164 |full-text-url=https://sci-hub.do/10.1007/s00586-018-5688-8 }} * {{medline-title |title=FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration. |date=10.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963746 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156454 }} * {{medline-title |title=Major traits of the senescent phenotype of nucleus pulposus intervertebral disc cells persist under the specific microenvironmental conditions of the tissue. |date=01.2019 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778758 |full-text-url=https://sci-hub.do/10.1016/j.mad.2018.05.007 }} * {{medline-title |title=[Influence analysis of aging of spinal segment on the mechanical behavior of vertebral cortex]. |date=01.06.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29745502 |full-text-url=https://sci-hub.do/10.7507/1001-5515.201608050 }} * {{medline-title |title=The adolescent idiopathic scoliotic [[IVD]] displays advanced aggrecanolysis and a glycosaminoglycan composition similar to that of aged human and ovine [[IVD]]s. |date=09.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29441417 |full-text-url=https://sci-hub.do/10.1007/s00586-018-5515-2 }} * {{medline-title |title=Costs and benefits of diagnostic testing: four ways to improve patient care by purposive use of in vitro diagnostics. |date=2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29185242 |full-text-url=https://sci-hub.do/10.4414/smw.2017.14546 }} * {{medline-title |title=Matrisome Profiling During Intervertebral Disc Development And Ageing. |date=14.09.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912585 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599645 }} * {{medline-title |title=Age-related decline in [[AMH]] is assay dependent limiting clinical interpretation of repeat [[AMH]] measures across the reproductive lifespan. |date=02.2018 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28792788 |full-text-url=https://sci-hub.do/10.1080/09513590.2017.1358708 }} * {{medline-title |title=Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration. |date=04.05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473691 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431421 }} * {{medline-title |title=Microcalcification of lumbar spine intervertebral discs and facet joints is associated with cartilage degeneration, but differs in prevalence and its relation to age. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28467655 |full-text-url=https://sci-hub.do/10.1002/jor.23591 }} * {{medline-title |title=Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration. |date=12.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28430387 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650945 }} * {{medline-title |title=Correlation of matrix metalloproteinase (MMP)-1, -2, -3, and -9 expressions with demographic and radiological features in primary lumbar intervertebral disc disease. |date=07.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28343922 |full-text-url=https://sci-hub.do/10.1016/j.jocn.2017.03.001 }} * {{medline-title |title=3D characterization of morphological changes in the intervertebral disc and endplate during aging: A propagation phase contrast synchrotron micro-tomography study. |date=07.03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28266560 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339826 }} * {{medline-title |title=Lumbar intervertebral discs T2 relaxometry and T1ρ relaxometry correlation with age in asymptomatic young adults. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27709076 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009110 }} * {{medline-title |title=Prevalence of Age-Related Changes in Ovine Lumbar Intervertebral Discs during Computed Tomography and Magnetic Resonance Imaging. |date=2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27538861 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983172 }} * {{medline-title |title=The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration. |date=03.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27489225 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446006 }} * {{medline-title |title=Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways. |date=02.07.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27192096 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957599 }} * {{medline-title |title=The aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae. |date=01.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27165182 |full-text-url=https://sci-hub.do/10.1007/s00586-016-4603-4 }} * {{medline-title |title=Molecular mechanisms of cell death in intervertebral disc degeneration (Review). |date=06.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27121482 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866972 }} * {{medline-title |title=Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration. |date=08.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27018499 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321132 }} * {{medline-title |title=Role of [[SHOX2]] in the development of intervertebral disc degeneration. |date=05.2017 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26697824 |full-text-url=https://sci-hub.do/10.1002/jor.23140 }} * {{medline-title |title=Age- and degeneration-related variations in cell density and glycosaminoglycan content in the human cervical intervertebral disc and its endplates. |date=09.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26619109 |full-text-url=https://sci-hub.do/10.5114/pjp.2015.54964 }} * {{medline-title |title=Aging and age related stresses: a senescence mechanism of intervertebral disc degeneration. |date=03.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26455958 |full-text-url=https://sci-hub.do/10.1016/j.joca.2015.09.019 }} * {{medline-title |title=Early changes in morphology, bone mineral density and matrix composition of vertebrae lead to disc degeneration in aged collagen IX -/- mice. |date=01.2016 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26429145 |full-text-url=https://sci-hub.do/10.1016/j.matbio.2015.09.005 }} * {{medline-title |title=Chronic ingestion of advanced glycation end products induces degenerative spinal changes and hypertrophy in aging pre-diabetic mice. |date=2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25668621 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323205 }} * {{medline-title |title=A computational analysis on the implications of age-related changes in the expression of cellular signals on the role of IGF-1 in intervertebral disc homeostasis. |date=21.01.2015 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25488135 |full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2014.11.021 }} * {{medline-title |title=Gene expression analysis in response to osmotic stimuli in the intervertebral disc with DNA microarray. |date=27.12.2013 |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24369767 |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3911967 }}
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