Редактирование: Aging genes 3-9

Перейти к навигации Перейти к поиску
Внимание: Вы не вошли в систему. Ваш IP-адрес будет общедоступен, если вы запишете какие-либо изменения. Если вы войдёте или создадите учётную запись, её имя будет использоваться вместо IP-адреса, наряду с другими преимуществами.

Правка может быть отменена. Пожалуйста, просмотрите сравнение версий ниже, чтобы убедиться, что это нужная вам правка, и запишите страницу ниже, чтобы отменить правку.

Текущая версия Ваш текст
Строка 7: Строка 7:
* [[Aging genes 1-2‎‎|Genes with 1-2 publications]]
* [[Aging genes 1-2‎‎|Genes with 1-2 publications]]


==ABO==
==ATG7==


* {{medline-title
* {{medline-title
|title=Allelic distribution of [i][[ABO]][/i] gene in Chinese centenarians.
|title=Age-related impairment of autophagy in cervical motor neurons.
|date=09.2020
|date=05.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33103040
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33290859
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574633
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111193
}}
}}
* {{medline-title
* {{medline-title
|title=Genetically Determined [[ABO]] Blood Group and its Associations With Health and Disease.
|title=Comprehensive Bioinformatics Identifies Key microRNA Players in [[ATG7]]-Deficient Lung Fibroblasts.
|date=03.2020
|date=09.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31969017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32527064
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.119.313658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312768
}}
}}
* {{medline-title
* {{medline-title
|title=Plasma proteomic and autoantibody profiles reveal the proteomic characteristics involved in longevity families in Bama, China.
|title=Regulation of autophagy by DNA G-quadruplexes.
|date=2019
|date=18.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31139026
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32420812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526601
|full-text-url=https://sci-hub.do/10.1080/15548627.2020.1769991
}}
}}
* {{medline-title
* {{medline-title
|title=Recipients with blood group A associated with longer survival rates in cardiac valvular bioprostheses.
|title=[[ATG7]] is essential for secretion of iron from ameloblasts and normal growth of murine incisors during aging.
|date=04.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30878598
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31880208
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491382
|full-text-url=https://sci-hub.do/10.1080/15548627.2019.1709764
}}
}}
* {{medline-title
* {{medline-title
|title=[[ABO]] blood group polymorphism has an impact on prostate, kidney and bladder cancer in association with longevity.
|title=Enhancing Autophagy Diminishes Aberrant Ca  Homeostasis and Arrhythmogenesis in Aging Rabbit Hearts.
|date=07.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061952
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31636573
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063046
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787934
}}
}}
* {{medline-title
* {{medline-title
|title=Aging and [[ABO]] blood type influence von Willebrand factor and factor VIII levels through interrelated mechanisms.
|title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity.
|date=05.2016
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26875505
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949873
|full-text-url=https://sci-hub.do/10.1089/cell.2019.0010
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity.
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=12.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26677855
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
}}
* {{medline-title
* {{medline-title
|title=Evolutionary aspects of [[ABO]] blood group in humans.
|title=Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line.
|date=15.04.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25689219
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29405784
|full-text-url=https://sci-hub.do/10.1016/j.cca.2015.02.016
|full-text-url=https://sci-hub.do/10.1080/21691401.2018.1434187
}}
}}
* {{medline-title
* {{medline-title
|title=Possible role of [[ABO]] system in age-related diseases and longevity: a narrative review.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=2014
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25512760
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265994
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==ACD==
==BAX==


* {{medline-title
* {{medline-title
|title=Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging.
|title=Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-X  -[[BAX]] interaction.
|date=02.12.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792241
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32652830
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889148
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530780
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in Ocular Parameters and Intraocular Lens Powers in Aging Cycloplegic Eyes.
|title=CREB Signaling Mediates Dose-Dependent Radiation Response in the Murine Hippocampus Two Years after Total Body Exposure.
|date=01.2017
|date=03.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27702623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31657930
|full-text-url=https://sci-hub.do/10.1016/j.ajo.2016.09.032
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00552
}}
}}
* {{medline-title
* {{medline-title
|title=Biometry and visual function of a healthy cohort in Leipzig, Germany.
|title=Reduced sucrose nonfermenting AMPK-related kinase (SNARK) activity aggravates cancer-induced skeletal muscle wasting.
|date=07.06.2016
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27268271
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31387190
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895813
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686878
}}
}}
* {{medline-title
* {{medline-title
|title=Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal.
|title=Modulated electro-hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro.
|date=22.03.2016
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27000202
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31183995
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802725
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675742
}}
}}
* {{medline-title
* {{medline-title
|title=Long-term effect of orthokeratology on the anterior segment length.
|title=The Clearance Effect of Tetrahedral DNA Nanostructures on Senescent Human Dermal Fibroblasts.
|date=08.2016
|date=16.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26905786
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30562007
|full-text-url=https://sci-hub.do/10.1016/j.clae.2016.02.003
|full-text-url=https://sci-hub.do/10.1021/acsami.8b20530
}}
}}
* {{medline-title
* {{medline-title
|title=Relationship between age, corneal astigmatism, and ocular dimensions with reference to astigmatism in eyes undergoing routine cataract surgery.
|title=Premature placental aging in term small-for-gestational-age and growth-restricted fetuses.
|date=04.2016
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26795412
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125412
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108535
|full-text-url=https://sci-hub.do/10.1002/uog.20103
}}
}}
* {{medline-title
* {{medline-title
|title=Iron Status and Inflammation in Early Stages of Chronic Kidney Disease.
|title=Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training.
|date=2015
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26160488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030137
|full-text-url=https://sci-hub.do/10.1159/000368512
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.011
}}
}}
* {{medline-title
* {{medline-title
|title=Regulation of autophagic cell death by glycogen synthase kinase-3β in adult hippocampal neural stem cells following insulin withdrawal.
|title=Xanthohumol exerts protective effects in liver alterations associated with aging.
|date=19.05.2015
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25986948
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29536163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436742
|full-text-url=https://sci-hub.do/10.1007/s00394-018-1657-6
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of age, refractive error and gender related changes of the cornea and the anterior segment of the eye with Scheimpflug imaging.
|title=Protective effect of xanthohumol against age-related brain damage.
|date=10.2015
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25910463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154
|full-text-url=https://sci-hub.do/10.1016/j.clae.2015.03.009
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011
}}
}}
==ADA==
==BRAF==


* {{medline-title
* {{medline-title
|title=Adenosine Metabolism in the Cerebral Cortex from Several Mice Models during Aging.
|title=Conditional reprograming culture conditions facilitate growth of lower grade glioma models.
|date=02.10.2020
|date=01.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33023260
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33258947
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582336
|full-text-url=https://sci-hub.do/10.1093/neuonc/noaa263
}}
}}
* {{medline-title
* {{medline-title
|title=Risk factors for diabetic kidney disease in adults with longstanding type 1 diabetes: results from the Canadian Study of Longevity in Diabetes.
|title=Active notch protects MAPK activated melanoma cell lines from MEK inhibitor cobimetinib.
|date=11.2019
|date=14.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31162987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33202284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566893
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2020.111006
}}
}}
* {{medline-title
* {{medline-title
|title=Ideglira is Associated With Improved Short-Term Clinical Outcomes and Cost Savings Compared with Insulin Glargine U100 Plus Insulin Aspart in the U.S.
|title=Mitochondrial metabolic reprograming via [[BRAF]] inhibition ameliorates senescence.
|date=09.2018
|date=15.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30308134
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31421186
|full-text-url=https://sci-hub.do/10.4158/EP-2018-0134
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110691
}}
}}
* {{medline-title
* {{medline-title
|title=Mismatch between [[ADA]] and AGS recommendations for glycated hemoglobin targets for older adults.
|title=Deciphering the genotype and phenotype of hairy cell leukemia: clues for diagnosis and treatment.
|date=04.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29396204
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282776
|full-text-url=https://sci-hub.do/10.1016/j.pcd.2018.01.003
|full-text-url=https://sci-hub.do/10.1080/1744666X.2019.1641405
}}
}}
* {{medline-title
* {{medline-title
|title=Manganese(II) Chloride Alters Nucleotide and Nucleoside Catabolism in Zebrafish (Danio rerio) Adult Brain.
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient.
|date=05.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28547528
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0601-8
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of Extracellular Nucleotide Metabolism in Adult Zebrafish After Embryological Exposure to Valproic Acid.
|title=Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf -Induced Tumorigenesis.
|date=07.2017
|date=11.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27189619
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753828
|full-text-url=https://sci-hub.do/10.1007/s12035-016-9917-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636642
}}
}}
* {{medline-title
* {{medline-title
|title=Web Accessibility for Older Adults: A Comparative Analysis of Disability Laws.
|title=Acquired resistance to [[BRAF]]i reverses senescence-like phenotype in mutant [[BRAF]] melanoma.
|date=10.2015
|date=07.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26156518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30159130
|full-text-url=https://sci-hub.do/10.1093/geront/gnv057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112757
}}
}}
* {{medline-title
* {{medline-title
|title=[Effect of electroacupuncture intervention on expression of testicular P 450 scc/17 β-HSD3 in rats with partial androgen deficiency].
|title=Cancer modeling by Transgene Electroporation in Adult Zebrafish (TEAZ).
|date=02.2015
|date=27.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25845214
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061297
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177007
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of zinc supplementation on E-[[ADA]] activity, seric zinc, and cytokines levels of Trypanosoma evansi infected Wistar rats.
|title=Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement.
|date=09.2014
|date=05.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24994023
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416771
|full-text-url=https://sci-hub.do/10.1016/j.micpath.2014.06.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788639
}}
}}
==ARNT==
==CCS==


* {{medline-title
* {{medline-title
|title=Loss of [[ARNT]] in skeletal muscle limits muscle regeneration in aging.
|title=Frailty Significantly Associated with a Risk for Mid-term Outcomes in Elderly Chronic Coronary Syndrome Patients: a Prospective Study.
|date=12.2020
|date=01.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33064329
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33306315
|full-text-url=https://sci-hub.do/10.1096/fj.202000761RR
|full-text-url=https://sci-hub.do/10.21470/1678-9741-2019-0484
}}
}}
* {{medline-title
* {{medline-title
|title=[Arylhydrocarbon receptor nuclear translocator ([[ARNT]]) in human skin during aging.]
|title=Microbleeds and Medial Temporal Atrophy Determine Cognitive Trajectories in Normal Aging: A Longitudinal PET-MRI Study.
|date=2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32925053
 
|full-text-url=https://sci-hub.do/10.3233/JAD-200559
}}
}}
* {{medline-title
* {{medline-title
|title=The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1.
|title=Hippocampal Volume Loss, Brain Amyloid Accumulation, and APOE Status in Cognitively Intact Elderly Subjects.
|date=03.04.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041778
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31846965
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135990
|full-text-url=https://sci-hub.do/10.1159/000504302
}}
}}
* {{medline-title
* {{medline-title
|title=Deficiency of Bmal1 disrupts the diurnal rhythm of haemostasis.
|title=Amyloid Load, Hippocampal Volume Loss, and Diffusion Tensor Imaging Changes in Early Phases of Brain Aging.
|date=04.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30610898
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31803008
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.12.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872975
}}
}}
* {{medline-title
* {{medline-title
|title=Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling.
|title=Lower bone mass is associated with subclinical atherosclerosis, endothelial dysfunction and carotid thickness in the very elderly.
|date=02.11.2018
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217816
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222112
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2019.11.007
}}
}}
* {{medline-title
* {{medline-title
|title=Aging and chromatoid body assembly: Are these two physiological events linked?
|title=Cardiovascular Risk Assessment and Follow-Up of Women After Hypertensive Disorders of Pregnancy:A Prospective Cohort Study.
|date=07.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29958504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30655227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108056
|full-text-url=https://sci-hub.do/10.1016/j.jogc.2018.10.024
}}
}}
* {{medline-title
* {{medline-title
|title=Deficiency of circadian clock protein BMAL1 in mice results in a low bone mass phenotype.
|title=T cell epigenetic remodeling and accelerated epigenetic aging are linked to long-term immune alterations in childhood cancer survivors.
|date=03.2016
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26789548
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400990
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219017
}}
}}
* {{medline-title
* {{medline-title
|title=Circadian clocks govern calorie restriction-mediated life span extension through BMAL1- and IGF-1-dependent mechanisms.
|title=Circulating microRNAs disclose biology of normal cognitive function in healthy elderly people - a discovery twin study.
|date=04.2016
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26700733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29720677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117263
}}
}}
* {{medline-title
* {{medline-title
|title=Whole blood thrombin generation in Bmal1-deficient mice.
|title=High risk of hypogonadism in young male cancer survivors.
|date=08.2014
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24740693
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29245176
|full-text-url=https://sci-hub.do/10.1160/TH13-11-0910
|full-text-url=https://sci-hub.do/10.1111/cen.13534
}}
}}
==AVP==
==CDK2==


* {{medline-title
* {{medline-title
|title=Plasma oxytocin and vasopressin levels in young and older men and women: Functional relationships with attachment and cognition.
|title=p57  is a master regulator of human adipose derived stem cell quiescence and senescence.
|date=12.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31606581
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32224418
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943921
|full-text-url=https://sci-hub.do/10.1016/j.scr.2020.101759
}}
}}
* {{medline-title
* {{medline-title
|title=Pathophysiological Mechanisms of Nocturia and Nocturnal Polyuria: The Contribution of Cellular Function, the Urinary Bladder Urothelium, and Circadian Rhythm.
|title=Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
|date=11.2019
|date=22.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31369749
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31112603
|full-text-url=https://sci-hub.do/10.1016/j.urology.2019.07.020
|full-text-url=https://sci-hub.do/10.1093/gerona/glz077
}}
}}
* {{medline-title
* {{medline-title
|title=Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension.
|title=Cyclin-Dependent Kinase 2 in Cellular Senescence and Cancer. A Structural and Functional Review.
|date=08.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140326
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30516105
|full-text-url=https://sci-hub.do/10.1080/07420528.2019.1613424
|full-text-url=https://sci-hub.do/10.2174/1389450120666181204165344
}}
}}
* {{medline-title
* {{medline-title
|title=The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system.
|title=Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes.
|date=05.2018
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29494864
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30092626
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513186
}}
}}
* {{medline-title
* {{medline-title
|title=Copeptin and insulin resistance: effect modification by age and 11 β-HSD2 activity in a population-based study.
|title=Relationship between intermuscular adipose tissue infiltration and myostatin before and after aerobic exercise training.
|date=07.2018
|date=01.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29235050
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718700
|full-text-url=https://sci-hub.do/10.1007/s40618-017-0807-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734080
}}
}}
* {{medline-title
* {{medline-title
|title=A decline in female baboon hypothalamo-pituitary-adrenal axis activity anticipates aging.
|title=Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line.
|date=09.05.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28490690
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29405784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472738
|full-text-url=https://sci-hub.do/10.1080/21691401.2018.1434187
}}
}}
* {{medline-title
* {{medline-title
|title=Hyponatremia and bone disease.
|title=Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress.
|date=03.2017
|date=20.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27664044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325896
|full-text-url=https://sci-hub.do/10.1007/s11154-016-9387-7
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.01.007
}}
}}
* {{medline-title
* {{medline-title
|title=Social peptides: measuring urinary oxytocin and vasopressin in a home field study of older adults at risk for dehydration.
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|date=11.2014
|date=08.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25360024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303104
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
}}
}}
* {{medline-title
* {{medline-title
|title=Renal physiology of nocturia.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=04.2014
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24729151
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://sci-hub.do/10.1002/nau.22594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==BMI1==
==CDK6==


* {{medline-title
* {{medline-title
|title=Senescence Induced by [[BMI1]] Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
|title=Saturated Fatty Acids Promote Hepatocytic Senecence through Regulation of miR-34a/Cyclin-Dependent Kinase 6.
|date=20.10.2020
|date=24.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33086074
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32970940
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574900
|full-text-url=https://sci-hub.do/10.1002/mnfr.202000383
}}
}}
* {{medline-title
* {{medline-title
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|title=Hepatoprotective effects of hydroxysafflor yellow A in D-galactose-treated aging mice.
|date=06.2019
|date=15.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32454116
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2020.173214
}}
}}
* {{medline-title
* {{medline-title
|title=Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein [[BMI1]] in breast cancer cells.
|title=Anti-cell growth and anti-cancer stem cell activity of the CDK4/6 inhibitor palbociclib in breast cancer cells.
|date=07.2018
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31823286
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986597
|full-text-url=https://sci-hub.do/10.1007/s12282-019-01035-5
}}
}}
* {{medline-title
* {{medline-title
|title=Suppressing P16 and P14  pathways overcomes apoptosis in individualized human embryonic stem cells.
|title=Compromising the constitutive p16 expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence.
|date=03.2017
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27965321
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31692039
|full-text-url=https://sci-hub.do/10.1096/fj.201600782R
|full-text-url=https://sci-hub.do/10.1002/jcb.29493
}}
}}
* {{medline-title
* {{medline-title
|title=[[BMI1]] inhibits senescence and enhances the immunomodulatory properties of human mesenchymal stem cells via the direct suppression of MKP-1/DUSP1.
|title=Palbociclib Effectively Halts Proliferation but Fails to Induce Senescence in Patient-Derived Glioma Stem Cells.
|date=08.2016
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27454161
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31124078
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032689
|full-text-url=https://sci-hub.do/10.1007/s12035-019-1633-z
}}
}}
* {{medline-title
* {{medline-title
|title=Adipose-derived stem cells from lean and obese humans show depot specific differences in their stem cell markers, exosome contents and senescence: role of protein kinase C delta (PKCδ) in adipose stem cell niche.
|title=Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth.
|date=2016
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27358894
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888162
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923648
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b00833
}}
}}
* {{medline-title
* {{medline-title
|title=A miR-200c/141-[[BMI1]] autoregulatory loop regulates oncogenic activity of [[BMI1]] in cancer cells.
|title=Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line.
|date=14.06.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27105531
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29405784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094995
|full-text-url=https://sci-hub.do/10.1080/21691401.2018.1434187
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence.
|title=Preclinical characterization of abemaciclib in hormone receptor positive breast cancer.
|date=17.04.2015
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25737447
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29050219
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400362
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642494
}}
}}
* {{medline-title
* {{medline-title
|title=PLK1 inhibition down-regulates polycomb group protein [[BMI1]] via modulation of the miR-200c/141 cluster.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=30.01.2015
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25505268
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==BNIP3==
==CX3CR1==


* {{medline-title
* {{medline-title
|title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training.
|title=Monocytes present age-related changes in phospholipid concentration and decreased energy metabolism.
|date=01.10.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32107839
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189998
}}
}}
* {{medline-title
* {{medline-title
|title=Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training.
|title=Muscle Injury Induces Postoperative Cognitive Dysfunction.
|date=01.10.2018
|date=17.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030137
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32066806
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026159
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of β-hydroxy-β-methylbutyrate on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults.
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|date=01.11.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28705993
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00192.2017
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
}}
}}
* {{medline-title
* {{medline-title
|title=Akt2 ablation prolongs life span and improves myocardial contractile function with adaptive cardiac remodeling: role of Sirt1-mediated autophagy regulation.
|title=Surgical Trauma Exacerbates Cognitive Deficits and Neuroinflammation in Aged Rats: The Role of [[CX3CL1]]-[[CX3CR1]] Signaling.
|date=10.2017
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28681509
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29939299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595687
|full-text-url=https://sci-hub.do/10.1093/jnen/nly051
}}
}}
* {{medline-title
* {{medline-title
|title=In Brief: Mitophagy: mechanisms and role in human disease.
|title=Repopulating retinal microglia restore endogenous organization and function under [[CX3CL1]]-[[CX3CR1]] regulation.
|date=11.2016
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27453450
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750189
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071152
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943055
}}
}}
* {{medline-title
* {{medline-title
|title=Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway.
|title=Cryopreserved whole blood for the quantification of monocyte, T-cell and NK-cell subsets, and monocyte receptor expression by multi-color flow cytometry: A methodological study based on participants from the canadian longitudinal study on aging.
|date=01.08.2016
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27334614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969577
|full-text-url=https://sci-hub.do/10.1002/cyto.a.23372
}}
}}
* {{medline-title
* {{medline-title
|title=Interfacing mitochondrial biogenesis and elimination to enhance host pathogen defense and longevity.
|title=Microglia and Aging: The Role of the [[TREM2]]-DAP12 and [[CX3CL1]]-[[CX3CR1]] Axes.
|date=07-09.2015
|date=22.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26430570
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29361745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588546
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796261
}}
}}
* {{medline-title
* {{medline-title
|title=Coupling mitogenesis and mitophagy for longevity.
|title=Strain specificities in age-related changes in mechanisms promoting and controlling rat spinal cord damage in experimental autoimmune encephalomyelitis.
|date=2015
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26083448
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29128575
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590656
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.002
}}
}}
* {{medline-title
* {{medline-title
|title=Dying myofibers in elderly mouse skeletal muscles are characterized by the appearance of dystrophin-encircled vacuoles.
|title=Sex as a determinant of age-related changes in rat spinal cord inflammation-oxidation state.
|date=08.2015
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25758773
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825141
|full-text-url=https://sci-hub.do/10.1007/s10522-015-9565-0
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9726-4
}}
}}
==CBS==
==DCX==


* {{medline-title
* {{medline-title
|title=Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity.
|title=GSK-3β activation accelerates early-stage consumption of Hippocampal Neurogenesis in senescent mice.
|date=02.08.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32800520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32863953
|full-text-url=https://sci-hub.do/10.1016/j.redox.2020.101668
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449917
}}
}}
* {{medline-title
* {{medline-title
|title=Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase.
|title=Doublecortin and IGF-1R protein levels are reduced in spite of unchanged DNA methylation in the hippocampus of aged rats.
|date=06.2020
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32027885
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32236698
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657663
|full-text-url=https://sci-hub.do/10.1007/s00726-020-02834-3
}}
}}
* {{medline-title
* {{medline-title
|title=Methionine restriction leads to hyperhomocysteinemia and alters hepatic H S production capacity in Fischer-344 rats.
|title=Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients.
|date=12.2018
|date=06.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30367932
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31130513
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.10.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608595
}}
}}
* {{medline-title
* {{medline-title
|title=Human Cord Blood Serum-Derived [[APP]] α-Secretase Cleavage Activity is Mediated by C1 Complement.
|title=Age-related changes in Ki-67 and [[DCX]] expression in the BALB/ c mouse (Mus Musculus) brain.
|date=04.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29871524
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020233
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.11.005
}}
}}
* {{medline-title
* {{medline-title
|title=Dietary and Endocrine Regulation of Endogenous Hydrogen Sulfide Production: Implications for Longevity.
|title=Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol.
|date=01.06.2018
|date=11.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29634343
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30201019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930795
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131894
}}
}}
* {{medline-title
* {{medline-title
|title=Nitration-mediated deficiency of cystathionine β-synthase activity accelerates the progression of hyperhomocysteinemia.
|title=Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice.
|date=12.2017
|date=04.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29102635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30181440
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.10.389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165152
}}
}}
* {{medline-title
* {{medline-title
|title=Standing sagittal alignment of the whole axial skeleton with reference to the gravity line in humans.
|title=Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning.
|date=05.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28127750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29793890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382592
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2018.05.007
}}
}}
* {{medline-title
* {{medline-title
|title=Hydrogen sulfide mediates the protection of dietary restriction against renal senescence in aged F344 rats.
|title=Hippocampal neurogenesis in the C57BL/6J mice at early adulthood following prenatal alcohol exposure.
|date=26.07.2016
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27456368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29164372
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960595
|full-text-url=https://sci-hub.do/10.1007/s11011-017-0156-4
}}
}}
* {{medline-title
* {{medline-title
|title=Hippocampal cystathionine beta synthase in young and aged mice.
|title=Puerarin and Amlodipine Improvement of D-Galactose-Induced Impairments of Behaviour and Neurogenesis in Mouse Dentate Gyrus: Correlation with Glucocorticoid Receptor Expression.
|date=20.03.2014
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24491430
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28831640
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2014.01.049
|full-text-url=https://sci-hub.do/10.1007/s11064-017-2366-x
}}
}}
==CD24==
==E2F1==


* {{medline-title
* {{medline-title
|title=[[CD24]] expression indicates healthier phenotype and less tendency of cellular senescence in human nucleus pulposus cells.
|title=Regulation of [[E2F1]] activity via PKA-mediated phosphorylations.
|date=12.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31334674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33110360
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1642205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585165
}}
}}
* {{medline-title
* {{medline-title
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|title=Astragaloside IV ameliorates radiation-induced senescence via antioxidative mechanism.
|date=05.07.2018
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32412100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
|full-text-url=https://sci-hub.do/10.1111/jphp.13284
}}
}}
* {{medline-title
* {{medline-title
|title=Some chemotherapeutics-treated colon cancer cells display a specific phenotype being a combination of stem-like and senescent cell features.
|title=[[E2F1]] mediates the downregulation of [[POLD1]] in replicative senescence.
|date=02.01.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053388
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30895337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588650
}}
}}
* {{medline-title
* {{medline-title
|title=Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration.
|title=Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing [[NRARP]].
|date=04.05.2017
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473691
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30274778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431421
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.09.045
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence-associated IL-6 and IL-8 cytokines induce a self- and cross-reinforced senescence/inflammatory milieu strengthening tumorigenic capabilities in the MCF-7 breast cancer cell line.
|title=Downregulation of [[FOXP1]] correlates with tendon stem/progenitor cells aging.
|date=04.05.2017
|date=26.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28472950
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30170733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418812
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.136
}}
}}
* {{medline-title
* {{medline-title
|title=[[CD24]] enrichment protects while its loss increases susceptibility of juvenile chondrocytes towards inflammation.
|title=Loss of circadian protein [[TIMELESS]] accelerates the progression of cellular senescence.
|date=12.12.2016
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27955675
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30100061
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153697
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.040
}}
}}
* {{medline-title
* {{medline-title
|title=Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration.
|title=Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence.
|date=08.2016
|date=30.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27018499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935093
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of [[CD24]] in Mice Leads to Metabolic Dysfunctions and a Reduction in White Adipocyte Tissue.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=2015
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26536476
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633231
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
* {{medline-title
* {{medline-title
|title=Similar ex vivo expansion and post-irradiation regenerative potential of juvenile and aged salivary gland stem cells.
|title=Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation
|date=09.2015
|date=27.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26138058
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952292
|full-text-url=https://sci-hub.do/10.1016/j.radonc.2015.06.022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660
}}
}}
==CD33==
==ELOVL2==


* {{medline-title
* {{medline-title
|title=Maximum reproductive lifespan correlates with [[CD33]]rSIGLEC gene number: Implications for NADPH oxidase-derived reactive oxygen species in aging.
|title=[[ELOVL2]]: Not just a biomarker of aging.
|date=02.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31907986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33043173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544151
}}
}}
* {{medline-title
* {{medline-title
|title=New genetic players in late-onset Alzheimer's disease: Findings of genome-wide association studies.
|title=The lipid elongation enzyme [[ELOVL2]] is a molecular regulator of aging in the retina.
|date=08.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30381536
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31943697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996962
}}
}}
* {{medline-title
* {{medline-title
|title=Chromogenic Multiplex Immunohistochemistry Reveals Modulation of the Immune Microenvironment Associated with Survival in Elderly Patients with Lung Adenocarcinoma.
|title=Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts.
|date=13.09.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216999
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162494
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691995
}}
}}
* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=Cell and tissue type independent age-associated DNA methylation changes are not rare but common.
|date=28.03.2018
|date=27.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30482885
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286821
}}
}}
* {{medline-title
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|title=DNA methylation of the [[ELOVL2]], [[FHL2]], [[KLF14]], C1orf132/MIR29B2C, and [[TRIM59]] genes for age prediction from blood, saliva, and buccal swab samples.
|date=11.04.2017
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30300865
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010
}}
}}
* {{medline-title
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|title=Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing.
|date=04.2016
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031222
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.07.007
}}
}}
* {{medline-title
* {{medline-title
|title=Impacts of [[CD33]] Genetic Variations on the Atrophy Rates of Hippocampus and Parahippocampal Gyrus in Normal Aging and Mild Cognitive Impairment.
|title=Age-related DNA methylation changes are tissue-specific with [[ELOVL2]] promoter methylation as exception.
|date=03.2017
|date=30.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26803496
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29848354
|full-text-url=https://sci-hub.do/10.1007/s12035-016-9718-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975493
}}
}}
* {{medline-title
* {{medline-title
|title=Human-specific derived alleles of [[CD33]] and other genes protect against postreproductive cognitive decline.
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird.
|date=05.01.2016
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26621708
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723
}}
}}
* {{medline-title
* {{medline-title
|title=Siglec receptors impact mammalian lifespan by modulating oxidative stress.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=07.04.2015
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25846707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384638
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==CXCL8==
==ERCC1==


* {{medline-title
* {{medline-title
|title=Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease.
|title=Chronic Sildenafil Treatment Improves Vasomotor Function in a Mouse Model of Accelerated Aging.
|date=2020
|date=30.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33041998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32630010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369923
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|title=Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction.
|date=2018
|date=17.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32202295
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
|full-text-url=https://sci-hub.do/10.1042/CS20190124
}}
}}
* {{medline-title
* {{medline-title
|title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort.
|title=Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice.
|date=03.2018
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31981461
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059165
}}
}}
* {{medline-title
* {{medline-title
|title=Predictive value of multiple cytokines and chemokines for mortality in an admixed population: 15-year follow-up of the Bambui-Epigen (Brazil) cohort study of aging.
|title=Deficiency in the DNA repair protein [[ERCC1]] triggers a link between senescence and apoptosis in human fibroblasts and mouse skin.
|date=11.2017
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803133
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31737985
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059167
}}
}}
* {{medline-title
* {{medline-title
|title=Gemcitabine induces cell senescence in human pancreatic cancer cell lines.
|title=Aerobic exercise promotes the expression of [[ERCC1]] to prolong lifespan: A new possible mechanism.
|date=26.08.2016
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27311854
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30593415
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.06.063
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2018.10.012
}}
}}
* {{medline-title
* {{medline-title
|title=In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant.
|title=Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging.
|date=07.2016
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27081760
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031267
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076207
}}
}}
* {{medline-title
* {{medline-title
|title=Senescent peritoneal mesothelium induces a pro-angiogenic phenotype in ovarian cancer cells in vitro and in a mouse xenograft model in vivo.
|title=[[ERCC1]]-deficient cells and mice are hypersensitive to lipid peroxidation.
|date=01.2016
|date=20.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26433963
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740564
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098728
}}
}}
* {{medline-title
* {{medline-title
|title=Colorectal cancer-promoting activity of the senescent peritoneal mesothelium.
|title=Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.
|date=06.10.2015
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26284488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29747066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006678
}}
}}
* {{medline-title
* {{medline-title
|title=[[CCL2]], [[CXCL8]], [[CXCL9]] and [[CXCL10]] serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees.
|title=Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice.
|date=12.2017
|date=09.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25955863
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415265
|full-text-url=https://sci-hub.do/10.1111/1756-185X.12589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887695
}}
}}
==CXCR2==
==FES==


* {{medline-title
* {{medline-title
|title=CXCL5-[[CXCR2]] signaling is a senescence-associated secretory phenotype in preimplantation embryos.
|title=An outpatient Tai Chi program: Effects on veterans' functional outcomes.
|date=10.2020
|date=26.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32959976
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33241873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576282
|full-text-url=https://sci-hub.do/10.1111/nuf.12532
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence in Wound Repair: Emerging Strategies to Target Chronic Healing Wounds.
|title=Gait Function in Adults Aged 50 Years and Older With Spina Bifida.
|date=2020
|date=07.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850866
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33166524
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431694
|full-text-url=https://sci-hub.do/10.1016/j.apmr.2020.10.118
}}
}}
* {{medline-title
* {{medline-title
|title=Cellular Senescence in Diabetic Wounds: When Too Many Retirees Stress the System.
|title=A Single Question as a Screening Tool to Assess Fear of Falling in Young-Old Community-Dwelling Persons.
|date=05.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31010531
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32165062
|full-text-url=https://sci-hub.do/10.1016/j.jid.2019.02.019
|full-text-url=https://sci-hub.do/10.1016/j.jamda.2020.01.101
}}
}}
* {{medline-title
* {{medline-title
|title=Elevated Local Senescence in Diabetic Wound Healing Is Linked to Pathological Repair via [[CXCR2]].
|title=Fall-related efficacy is a useful and independent index to detect fall risk in Japanese community-dwelling older people: a 1-year longitudinal study.
|date=05.2019
|date=29.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684552
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31664911
|full-text-url=https://sci-hub.do/10.1016/j.jid.2019.01.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820944
}}
}}
* {{medline-title
* {{medline-title
|title=A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.
|title=Investigating Changes in Real-time Conscious Postural Processing by Older Adults during Different Stance Positions Using Electroencephalography Coherence.
|date=19.02.2019
|date=10-12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30709741
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31514583
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2019.01.002
|full-text-url=https://sci-hub.do/10.1080/0361073X.2019.1664450
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic Resveratrol Treatment Reduces the Pro-angiogenic Effect of Human Fibroblast "Senescent-Associated Secretory Phenotype" on Endothelial Colony-Forming Cells: The Role of IL8.
|title=Effectiveness of Daily Use of Bilateral Custom-Made Ankle-Foot Orthoses on Balance, Fear of Falling, and Physical Activity in Older Adults: A Randomized Controlled Trial.
|date=23.04.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30084946
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30504728
|full-text-url=https://sci-hub.do/10.1093/gerona/gly175
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530116
}}
}}
* {{medline-title
* {{medline-title
|title=Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells.
|title=Decline in sensorimotor systems explains reduced falls self-efficacy.
|date=15.06.2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28418782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30015133
|full-text-url=https://sci-hub.do/10.1089/scd.2016.0324
|full-text-url=https://sci-hub.do/10.1016/j.jelekin.2018.07.001
}}
}}
* {{medline-title
* {{medline-title
|title=Habitual physical activity is associated with the maintenance of neutrophil migratory dynamics in healthy older adults.
|title=Fear of Falling in Older Adults with Diabetes Mellitus: The IMIAS Study.
|date=08.2016
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26928196
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29956644
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929133
|full-text-url=https://sci-hub.do/10.1017/S071498081800020X
}}
}}
* {{medline-title
* {{medline-title
|title=[[CXCL1]] Triggers Caspase-3 Dependent Tau Cleavage in Long-Term Neuronal Cultures and in the Hippocampus of Aged Mice: Implications in Alzheimer's Disease.
|title=Cross-cultural adaptation and measurement properties testing of the Iconographical Falls Efficacy Scale (Icon-[[FES]]).
|date=2015
|date=07-08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26401931
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486980
|full-text-url=https://sci-hub.do/10.3233/JAD-150041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095044
}}
}}
==DBI==
==HSF1==


* {{medline-title
* {{medline-title
|title=Quantifying cumulative anticholinergic and sedative drug load among US Medicare Beneficiaries.
|title=A Mitochondrial Stress-Specific Form of [[HSF1]] Protects against Age-Related Proteostasis Collapse.
|date=01.10.2020
|date=28.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33000867
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32735771
|full-text-url=https://sci-hub.do/10.1002/pds.5144
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2020.06.038
}}
}}
* {{medline-title
* {{medline-title
|title=Drug Burden Index and Cognitive and Physical Function in Aged Care Residents: A Longitudinal Study.
|title=Heat shock factor 1-mediated transcription activation of Omi/HtrA2 induces myocardial mitochondrial apoptosis in the aging heart.
|date=08.2020
|date=18.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736845
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31627188
|full-text-url=https://sci-hub.do/10.1016/j.jamda.2020.05.037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834417
}}
}}
* {{medline-title
* {{medline-title
|title=Using the Drug Burden Index to identify older adults at highest risk for medication-related falls.
|title=Multifactorial Attenuation of the Murine Heat Shock Response With Age.
|date=12.06.2020
|date=25.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32532276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31612204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291506
|full-text-url=https://sci-hub.do/10.1093/gerona/glz204
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of STEADI-Rx: A Community Pharmacy-Based Fall Prevention Intervention.
|title=Nutrition and water temperature regulate the expression of heat-shock proteins in golden pompano larvae (Trachinotus ovata, Limmaeus 1758).
|date=08.2020
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32315461
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30397841
|full-text-url=https://sci-hub.do/10.1111/jgs.16459
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0578-x
}}
}}
* {{medline-title
* {{medline-title
|title=Association of Drug Burden Index with grip strength, timed up and go and Barthel index activities of daily living in older adults with intellectual disabilities: an observational cross-sectional study.
|title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans.
|date=24.06.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31234775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591943
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of drug burden index on adverse health outcomes in Irish community-dwelling older people: a cohort study.
|title=Modulation of Heat Shock Factor 1 Activity through Silencing of Ser303/Ser307 Phosphorylation Supports a Metabolic Program Leading to Age-Related Obesity and Insulin Resistance.
|date=29.04.2019
|date=15.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31035946
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489229
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113599
}}
}}
* {{medline-title
* {{medline-title
|title=Dietary Balance Index-07 and the Risk of Anemia in Middle Aged and Elderly People in Southwest China: A Cross Sectional Study.
|title=The longevity SNP rs2802292 uncovered: [[HSF1]] activates stress-dependent expression of [[FOXO3]] through an intronic enhancer.
|date=31.01.2018
|date=20.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29385057
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852738
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009585
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Changes in Number of Medications and Drug Burden Index Exposure on Transitions Between Frailty States and Death: The Concord Health and Ageing in Men Project Cohort Study.
|title=Acute [[HSF1]] depletion induces cellular senescence through the [[MDM2]]-p53-p21 pathway in human diploid fibroblasts.
|date=01.2016
|date=08.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26782856
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632240
|full-text-url=https://sci-hub.do/10.1111/jgs.13877
|full-text-url=https://sci-hub.do/10.1242/jcs.210724
}}
}}
* {{medline-title
* {{medline-title
|title=Drug Burden Index score and anticholinergic risk scale as predictors of readmission to the hospital.
|title=Azadiradione Restores Protein Quality Control and Ameliorates the Disease Pathogenesis in a Mouse Model of Huntington's Disease.
|date=03.2014
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589765
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29294248
|full-text-url=https://sci-hub.do/10.4140/TCP.n.2014.158
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0853-3
}}
}}
==DPP4==
==JAK2==


* {{medline-title
* {{medline-title
|title=Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-[[DPP4]] Axis.
|title=Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity.
|date=2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013423
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850477
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510459
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399640
}}
}}
* {{medline-title
* {{medline-title
|title=Dipeptidyl peptidase-4 inhibition improves endothelial senescence by activating AMPK/SIRT1/Nrf2 signaling pathway.
|title=Quercetin Directly Targets [[JAK2]] and PKCδ and Prevents UV-Induced Photoaging in Human Skin.
|date=07.2020
|date=23.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32251672
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31652815
|full-text-url=https://sci-hub.do/10.1016/j.bcp.2020.113951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862686
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular crosstalk between Y5 receptor and neuropeptide Y drives liver cancer.
|title=[Red blood cell lifespan detected by endogenous carbon monoxide breath test in patients with polycythemia vera].
|date=01.05.2020
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31999643
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31594177
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190991
|full-text-url=https://sci-hub.do/10.3760/cma.j.issn.0578-1426.2019.10.010
}}
}}
* {{medline-title
* {{medline-title
|title=Dose rectification of an imbalance between [[DPP4]] and GLP-1 ameliorates chronic stress-related vascular aging and atherosclerosis?
|title=Roles of [[JAK2]] in Aging, Inflammation, Hematopoiesis and Malignant Transformation.
|date=05.2018
|date=08.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29220092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31398915
|full-text-url=https://sci-hub.do/10.1111/1440-1681.12903
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721738
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis.
|title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver.
|date=28.09.2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28963101
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of senescent cell surface targetable protein [[DPP4]].
|title=Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development.
|date=01.08.2017
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28877934
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30417440
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630018
|full-text-url=https://sci-hub.do/10.1002/jcp.27752
}}
}}
* {{medline-title
* {{medline-title
|title=Increased dipeptidyl peptidase-4 accelerates diet-related vascular aging and atherosclerosis in ApoE-deficient mice under chronic stress.
|title=Distinctive features of polycythaemia vera in New Zealand Polynesians.
|date=15.09.2017
|date=21.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28549747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235191
|full-text-url=https://sci-hub.do/10.1016/j.ijcard.2017.05.062
 
}}
}}
* {{medline-title
* {{medline-title
|title=Sarcopenia in Elderly Diabetic Patients: Role of Dipeptidyl Peptidase 4 Inhibitors.
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|date=01.10.2016
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27262494
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|full-text-url=https://sci-hub.do/10.1016/j.jamda.2016.04.016
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
}}
}}
* {{medline-title
* {{medline-title
|title=Teneligliptin improves metabolic abnormalities in a mouse model of postmenopausal obesity.
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender.
|date=10.2015
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26264980
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454
|full-text-url=https://sci-hub.do/10.1530/JOE-15-0239
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0
}}
}}
==FNDC5==
==LPO==


* {{medline-title
* {{medline-title
|title=Irisin Correlates Positively With BMD in a Cohort of Older Adult Patients and Downregulates the Senescent Marker p21 in Osteoblasts.
|title=[Features of the changes in lipid peroxidation and activity of Na+/K+-ATPase in the brain of the aged rats in the conditions of two-vessel cerebral ischemia/reperfusion.]
|date=14.10.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33053231
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32160433
|full-text-url=https://sci-hub.do/10.1002/jbmr.4192
 
}}
}}
* {{medline-title
* {{medline-title
|title=[Investigation of signal molecules in saliva: prospects of application for diagnostics of myocardial infarction and the aging rate of different age people.]
|title=Exercise training initiated at old stage of lifespan attenuates aging-and ovariectomy-induced cardiac and renal oxidative stress: Role of baroreflex.
|date=2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31512422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31195102
 
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110635
}}
}}
* {{medline-title
* {{medline-title
|title=Mechanistic complexities of bone loss in Alzheimer's disease: a review.
|title=Tris(1,3-dichloro-2-propyl) phosphate accelerated the aging process induced by the 4-hydroxynon-2-enal response to reactive oxidative species in Caenorhabditis elegans.
|date=01.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31184223
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31159140
|full-text-url=https://sci-hub.do/10.1080/03008207.2019.1624734
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2018.12.082
}}
}}
* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Physical Exercise Attenuates Oxidative Stress and Morphofunctional Cerebellar Damages Induced by the Ethanol Binge Drinking Paradigm from Adolescence to Adulthood in Rats.
|date=11.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911348
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398010
}}
}}
* {{medline-title
* {{medline-title
|title=Exercise Training Protects Against Aging-Induced Cognitive Dysfunction via Activation of the Hippocampal [[PGC]]-1α/[[FNDC5]]/[[BDNF]] Pathway.
|title=[Effect of cryopreserved cord blood nucleated cells on course of pathological processes in progressive aging of brain (experimental study).]
|date=09.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29971668
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30584872
|full-text-url=https://sci-hub.do/10.1007/s12017-018-8500-3
 
}}
}}
* {{medline-title
* {{medline-title
|title=Epistasis, physical capacity-related genes and exceptional longevity: [[FNDC5]] gene interactions with candidate genes FOXOA3 and [[APOE]].
|title=Analysis of Plasma MicroRNAs as Predictors and Biomarkers of Aging and Frailty in Humans.
|date=14.11.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688477
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079380
}}
}}
* {{medline-title
* {{medline-title
|title=Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice.
|title=[[ERCC1]]-deficient cells and mice are hypersensitive to lipid peroxidation.
|date=04.2017
|date=20.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28108329
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346470
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098728
}}
}}
* {{medline-title
* {{medline-title
|title=Irisin-encoding gene ([[FNDC5]]) variant is associated with changes in blood pressure and lipid profile in type 2 diabetic women but not in men.
|title=Antioxidant action of grape seed polyphenols and aerobic exercise in improving neuronal number in the hippocampus is associated with decrease in lipid peroxidation and hydrogen peroxide in adult and middle-aged rats.
|date=09.2015
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26024756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29174497
|full-text-url=https://sci-hub.do/10.1016/j.metabol.2015.05.005
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.012
}}
}}
* {{medline-title
* {{medline-title
|title=[[FNDC5]] (irisin) gene and exceptional longevity: a functional replication study with rs16835198 and rs726344 SNPs.
|title=The antioxidative and anti-aging effects of acidic- and alkalic-extractable mycelium polysaccharides by Agrocybe aegerita (Brig.) Sing.
|date=2014
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25427998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28851637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245403
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2017.08.138
}}
}}
==FOXM1==
==MFN2==


* {{medline-title
* {{medline-title
|title=Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression.
|title=Thioredoxin protects mitochondrial structure, function and biogenesis in myocardial ischemia-reperfusion via redox-dependent activation of AKT-CREB- PGC1α pathway in aged mice.
|date=10.11.2020
|date=13.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33171439
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33049718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695388
|full-text-url=https://sci-hub.do/10.18632/aging.104071
}}
* {{medline-title
|title=[[MFN2]] contributes to metabolic disorders and inflammation in the aging of rat chondrocytes and osteoarthritis.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32416221
|full-text-url=https://sci-hub.do/10.1016/j.joca.2019.11.011
}}
}}
* {{medline-title
* {{medline-title
|title=Upregulation of [[FOXM1]] leads to diminished drug sensitivity in myeloma.
|title=Mitofusin 2 plays a role in oocyte and follicle development, and is required to maintain ovarian follicular reserve during reproductive aging.
|date=21.11.2018
|date=16.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31204316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628992
}}
}}
* {{medline-title
* {{medline-title
|title=Preclinical characterization of abemaciclib in hormone receptor positive breast cancer.
|title=Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides.
|date=19.09.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29050219
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31024341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642494
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467974
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
|title=Low [[MFN2]] expression related to ageing in granulosa cells is associated with assisted reproductive technology outcome.
|date=02.10.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30593438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654
|full-text-url=https://sci-hub.do/10.1016/j.rbmo.2018.10.011
}}
}}
* {{medline-title
* {{medline-title
|title=[[FOXM1]] regulates proliferation, senescence and oxidative stress in keratinocytes and cancer cells.
|title=Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers.
|date=07.2016
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27385468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774638
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052398
}}
}}
* {{medline-title
* {{medline-title
|title=[[MELK]]-T1, a small-molecule inhibitor of protein kinase [[MELK]], decreases DNA-damage tolerance in proliferating cancer cells.
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.
|date=02.10.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26431963
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643329
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
}}
}}
* {{medline-title
* {{medline-title
|title=Increased [[FOXM1]] expression can stimulate DNA repair in normal hepatocytes in vivo but also increases nuclear foci associated with senescence.
|title=Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease.
|date=02.2015
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25477198
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29201274
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522743
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672147
}}
}}
* {{medline-title
* {{medline-title
|title=Cellular senescence and aging: the role of B-[[MYB]].
|title=Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats.
|date=10.2014
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24981831
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331756
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.017
}}
* {{medline-title
|title=MiR-506 suppresses proliferation and induces senescence by directly targeting the [[CDK4]]/6-[[FOXM1]] axis in ovarian cancer.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24604117
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144705
}}
}}
==GSS==
==TSPO==


* {{medline-title
* {{medline-title
|title=Geriatric brain tumor management part I: Meningioma.
|title=Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge.
|date=09.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208835
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31749696
|full-text-url=https://sci-hub.do/10.1016/j.jocn.2019.05.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848890
}}
}}
* {{medline-title
* {{medline-title
|title=Link between cardiac function and the antioxidative defense mechanism in aged rats.
|title=Upregulation of cannabinoid receptor type 2, but not [[TSPO]], in senescence-accelerated neuroinflammation in mice: a positron emission tomography study.
|date=11.06.2019
|date=10.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31010674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31707986
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.03.182
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842455
}}
}}
* {{medline-title
* {{medline-title
|title=Towards improving sterile insect technique: Exposure to orange oil compounds increases sexual signalling and longevity in Ceratitis capitata males of the Vienna 8 [[GSS]].
|title=Effects of age, BMI and sex on the glial cell marker [[[[TSPO]]]] - a multicentre [ C]PBR28 HRRT PET study.
|date=2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29190755
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31363804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717599
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling.
|title=Concentration, distribution, and influence of aging on the 18 kDa translocator protein in human brain: Implications for brain imaging studies.
|date=2015
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27004051
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220997
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181090
}}
}}
* {{medline-title
* {{medline-title
|title=Comparison of Anastrepha ludens (Diptera: Tephritidae) Bisexual and Genetic Sexing (Tapachula-7) Strains: Effect of Hypoxia, Fly Density, Chilling Period, and Food Type on Fly Quality.
|title=Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study.
|date=04.2016
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26685109
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400912
|full-text-url=https://sci-hub.do/10.1093/jee/tov350
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220478
}}
}}
* {{medline-title
* {{medline-title
|title=The Geriatric Scoring System ([[GSS]]) for Risk Stratification in Meningioma Patients as a Predictor of Outcome in Patients Treated with Radiosurgery.
|title=Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
|date=03.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26548822
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297998
|full-text-url=https://sci-hub.do/10.1016/j.wneu.2015.10.081
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739
}}
}}
* {{medline-title
* {{medline-title
|title='Start to finish trans-institutional transdisciplinary care': a novel approach improves colorectal surgical results in frail elderly patients.
|title=[[[[TSPO]]]] ligand PK11195 improves Alzheimer-related outcomes in aged female 3xTg-AD mice.
|date=01.2016
|date=14.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26500155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29925037
|full-text-url=https://sci-hub.do/10.1111/codi.13166
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436542
}}
}}
* {{medline-title
* {{medline-title
|title=Combined inhibitory effects of low temperature and N-acetyl-l-cysteine on the postovulatory aging of mouse oocytes.
|title=Imaging studies of the HIV-infected brain.
|date=04.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25801325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604980
|full-text-url=https://sci-hub.do/10.1017/S0967199415000039
|full-text-url=https://sci-hub.do/10.1016/B978-0-444-63849-6.00018-9
}}
}}
* {{medline-title
* {{medline-title
|title=Aging alters circadian regulation of redox in Drosophila.
|title=Steroidogenic abnormalities in translocator protein knockout mice and significance in the aging male.
|date=2015
|date=02.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25806044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29127254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353305
|full-text-url=https://sci-hub.do/10.1042/BCJ20170645
}}
}}
==ICOS==
==XBP1==


* {{medline-title
* {{medline-title
|title=The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy.
|title=Age-dependent impairment of adipose-derived stem cells isolated from horses.
|date=2018
|date=03.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30560130
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31900232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942290
}}
}}
* {{medline-title
* {{medline-title
|title=End-stage renal disease, dialysis, kidney transplantation and their impact on [[CD4]]  T-cell differentiation.
|title=Effects of a resistance-training programme on endoplasmic reticulum unfolded protein response and mitochondrial functions in PBMCs from elderly subjects.
|date=10.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29722011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30614406
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142287
|full-text-url=https://sci-hub.do/10.1080/17461391.2018.1561950
}}
}}
* {{medline-title
* {{medline-title
|title=Characterization of Blimp-1 function in effector regulatory T cells.
|title=[Protective effect of Wuzi Yanzong recipe on testicular germ cell apoptosis in natural ageing rats through endoplasmic reticulum stress].
|date=07.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29724515
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453716
|full-text-url=https://sci-hub.do/10.1016/j.jaut.2018.04.003
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180530.001
}}
}}
* {{medline-title
* {{medline-title
|title=Functional exhaustion of [[CD4]]  T cells induced by co-stimulatory signals from myeloid leukaemia cells.
|title=Protective effect of Wuzi Yanzong recipe on testicular dysfunction through inhibition of germ cell apoptosis in ageing rats via endoplasmic reticulum stress.
|date=12.2016
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27565576
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30393883
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095494
|full-text-url=https://sci-hub.do/10.1111/and.13181
}}
}}
* {{medline-title
* {{medline-title
|title=Development of a novel monoclonal antibody to human inducible co-stimulator ligand ([[ICOS]]L): Biological characteristics and application for enzyme-linked immunosorbent assay.
|title=Loss of [[XBP1]] accelerates age-related decline in retinal function and neurodegeneration.
|date=07.2016
|date=04.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27138044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615095
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2016.04.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883257
}}
}}
* {{medline-title
* {{medline-title
|title=Defective TFH Cell Function and Increased TFR Cells Contribute to Defective Antibody Production in Aging.
|title=A decay of the adaptive capacity of the unfolded protein response exacerbates Alzheimer's disease.
|date=14.07.2015
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26146074
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29042130
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504745
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.09.012
}}
}}
* {{medline-title
* {{medline-title
|title=IL-6 and [[ICOS]] Antagonize Bim and Promote Regulatory T Cell Accrual with Age.
|title=Amyloid-β42 clearance and neuroprotection mediated by X-box binding protein 1 signaling decline with aging in the Drosophila brain.
|date=01.08.2015
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26109645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28917667
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506860
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.08.012
}}
}}
* {{medline-title
* {{medline-title
|title=Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation.
|title=Ageing sensitized by iPLA β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids.
|date=21.07.2015
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26092469
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512852
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2017.09.001
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating CXCR5 PD-1  response predicts influenza vaccine antibody responses in young adults but not elderly adults.
|title=ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
|date=01.10.2014
|date=12.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25172499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847931
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603998
}}
}}
==IL1B==
==BCL2==


* {{medline-title
* {{medline-title
|title=Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B.
|title=Soy isoflavones protect against oxidative stress and diminish apoptosis in ovary of middle-aged female rats.
|date=18.04.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30998506
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542605
|full-text-url=https://sci-hub.do/10.1080/09513590.2018.1559287
}}
}}
* {{medline-title
* {{medline-title
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|title=Nrdp1 is involved in hippocampus apoptosis in cardiopulmonary bypass-induced cognitive dysfunction via the regulation of ErbB3 protein levels.
|date=18.03.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30720051
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414174
}}
}}
* {{medline-title
* {{medline-title
|title=Measuring the Inflammasome in Oncogene-Induced Senescence.
|title=Self-Digestion for Lifespan Extension: Enhanced Autophagy Delays Aging.
|date=2019
|date=16.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30474840
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30118677
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-8931-7_7
|full-text-url=https://sci-hub.do/10.1016/j.molcel.2018.08.002
}}
}}
* {{medline-title
* {{medline-title
|title=Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin.
|title=Disruption of the beclin 1-[[BCL2]] autophagy regulatory complex promotes longevity in mice.
|date=01.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28777886
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29849149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992097
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent changes in inflammation and extracellular matrix in bovine oviduct epithelial cells during the post-ovulatory phase.
|title=Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis.
|date=09.2016
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27580129
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751091
|full-text-url=https://sci-hub.do/10.1002/mrd.22693
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.006
}}
}}
* {{medline-title
* {{medline-title
|title=Differential Matrix Metalloprotease (MMP) Expression Profiles Found in Aged Gingiva.
|title=Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-[[ULK1]] signaling pathway.
|date=2016
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344647
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810242
}}
}}
* {{medline-title
* {{medline-title
|title=Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age.
|title=The effect of [[ARC]] ablation on skeletal muscle morphology, function, and apoptotic signaling during aging.
|date=2015
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448778
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29056555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596365
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.10.018
}}
}}
* {{medline-title
* {{medline-title
|title=Gene expression markers of age-related inflammation in two human cohorts.
|title=High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.
|date=10.2015
|date=17.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26087330
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29045843
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600657
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2017.09.085
}}
* {{medline-title
|title=Prior infection exacerbates postoperative cognitive dysfunction in aged rats.
|date=15.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25972458
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00002.2015
}}
}}
==LSS==
==CDKN2A==


* {{medline-title
* {{medline-title
|title=Surgical results in older patients with lumbar spinal stenosis according to gait speed in relation to the diagnosis for sarcopenia.
|title=Association between Nrf2 and [[CDKN2A]] expression in patients with end-stage renal disease: a pilot study.
|date=01-04.2020
|date=13.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32329390
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32661200
|full-text-url=https://sci-hub.do/10.1177/2309499020918422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485736
}}
}}
* {{medline-title
* {{medline-title
|title=Streamlining an existing hip fracture patient pathway in an acute tertiary adult Irish hospital to improve patient experience and outcomes.
|title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.
|date=22.12.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31867664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141
}}
}}
* {{medline-title
* {{medline-title
|title=Low-dose radiation from A-bombs elongated lifespan and reduced cancer mortality relative to un-irradiated individuals.
|title=Analysis of the putative tumor suppressor gene cdkn2ab in pigment cells and melanoma of Xiphophorus and medaka.
|date=2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30598710
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377863
}}
}}
* {{medline-title
* {{medline-title
|title=Lung, Laryngeal and Other Respiratory Cancer Incidence among Japanese Atomic Bomb Survivors: An Updated Analysis from 1958 through 2009.
|title=In vitro behavior and UV response of melanocytes derived from carriers of [[[[CDKN2A]]]] mutations and [[MC1R]] variants.
|date=05.2017
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28323575
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505071
|full-text-url=https://sci-hub.do/10.1111/pcmr.12732
}}
}}
* {{medline-title
* {{medline-title
|title=Quantitating the lateral skin stiffness by a new and versatile electro-mechanical instrument. Preliminary studies.
|title=Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging.
|date=08.2017
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27896851
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29735632
|full-text-url=https://sci-hub.do/10.1111/srt.12331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002945
}}
}}
* {{medline-title
* {{medline-title
|title=A message to Fukushima: nothing to fear but fear itself.
|title=Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16  inactivation.
|date=2016
|date=26.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27350831
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482580
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918197
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828408
}}
}}
* {{medline-title
* {{medline-title
|title=Exposure to ionizing radiation and brain cancer incidence: The Life Span Study cohort.
|title=Cellular aging dynamics after acute malaria infection: A 12-month longitudinal study.
|date=06.2016
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27038588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143441
|full-text-url=https://sci-hub.do/10.1016/j.canep.2016.03.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771395
}}
}}
* {{medline-title
* {{medline-title
|title=Lumbar spondylosis, lumbar spinal stenosis, knee pain, back muscle strength are associated with the locomotive syndrome: Rural population study in Japan.
|title=[[ARID1A]] suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[[[CDKN2A]]]] regulatory axis.
|date=05.2016
|date=18.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27021251
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942143
|full-text-url=https://sci-hub.do/10.1016/j.jos.2016.02.006
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.099
}}
* {{medline-title
|title=Does Obesity Affect Outcomes After Decompressive Surgery for Lumbar Spinal Stenosis? A Multicenter, Observational, Registry-Based Study.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26100169
|full-text-url=https://sci-hub.do/10.1016/j.wneu.2015.06.020
}}
}}
==MGMT==
==CFTR==


* {{medline-title
* {{medline-title
|title=Cytotoxic and Senolytic Effects of Methadone in Combination with Temozolomide in Glioblastoma Cells.
|title=Exercise Physiology Across the Lifespan in Cystic Fibrosis.
|date=23.09.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32977591
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31780953
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856653
}}
}}
* {{medline-title
* {{medline-title
|title=Profound, durable and [[MGMT]]-independent sensitivity of glioblastoma cells to cyclin-dependent kinase inhibition.
|title=Reduced expression of the Ion channel [[CFTR]] contributes to airspace enlargement as a consequence of aging and in response to cigarette smoke in mice.
|date=01.07.2019
|date=02.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30549269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31477092
|full-text-url=https://sci-hub.do/10.1002/ijc.32069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720379
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of aging in the modulation of epigenetic biomarkers of carcinogenesis after exposure to air pollution.
|title=Is cellular senescence involved in cystic fibrosis?
|date=09.2018
|date=14.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860068
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30764828
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376730
}}
}}
* {{medline-title
* {{medline-title
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats.
|title=Autophagy delays progression of the two most frequent human monogenetic lethal diseases: cystic fibrosis and Wilson disease.
|date=01.2018
|date=19.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30568028
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326686
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=The Clinical Biology of Cystic Fibrosis Transmembrane Regulator Protein: Its Role and Function in Extrapulmonary Disease.
|date=02.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30359614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414788
}}
}}
* {{medline-title
* {{medline-title
|title=mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and [[PAPPA]]-KO mice.
|title=[Ageing with cystic fibrosis: Classical and emerging comorbidities in adults with cystic fibrosis].
|date=02.2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27618784
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30316653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242303
|full-text-url=https://sci-hub.do/10.1016/j.pneumo.2018.09.012
}}
}}
* {{medline-title
* {{medline-title
|title=GBM-associated mutations and altered protein expression are more common in young patients.
|title=A review of inflammatory mechanism in airway diseases.
|date=25.10.2016
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30306206
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491
|full-text-url=https://sci-hub.do/10.1007/s00011-018-1191-2
}}
}}
* {{medline-title
* {{medline-title
|title=Ursolic acid attenuates temozolomide resistance in glioblastoma cells by downregulating O(6)-methylguanine-DNA methyltransferase ([[MGMT]]) expression.
|title=Up-to-date and projected estimates of survival for people with cystic fibrosis using baseline characteristics: A longitudinal study using UK patient registry data.
|date=2016
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27508051
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29311001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885983
}}
* {{medline-title
|title=Expression and methylation of DNA repair genes in lens epithelium cells of age-related cataract.
|date=08-09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25847269
|full-text-url=https://sci-hub.do/10.1016/j.mrfmmm.2014.05.010
}}
}}
==MIF==
==COMT==


* {{medline-title
* {{medline-title
|title=Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice.
|title=The geriatric pain experience in mice: intact cutaneous thresholds but altered responses to tonic and chronic pain.
|date=09.2019
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31381889
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32008855
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718337
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.12.018
}}
}}
* {{medline-title
* {{medline-title
|title=Macrophage migration inhibitory factor knockdown inhibit viability and induce apoptosis of PVM/Ms.
|title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.
|date=12.2017
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28990052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608707
}}
}}
* {{medline-title
* {{medline-title
|title=Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded [[SOD1]] in a mouse model of ALS.
|title=Frontoparietal cortical thickness mediates the effect of [[COMT]] Val Met polymorphism on age-associated executive function.
|date=06.09.2016
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27551074
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30342271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018779
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251730
}}
}}
* {{medline-title
* {{medline-title
|title=Macrophage Migration Inhibitory Factor ([[MIF]]) Deficiency Exacerbates Aging-Induced Cardiac Remodeling and Dysfunction Despite Improved Inflammation: Role of Autophagy Regulation.
|title=[MELATONIN: THE POSSIBILITY TO ANALYSE THE MARKER OF AGE-RELATED PATHOLOGY IN THE BUCCAL EPITHELIUM AND URINE].
|date=04.03.2016
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26940544
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30303666
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778027
 
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent alterations in the inflammatory response to pulmonary challenge.
|title=The Moderating Role of [[COMT]] and [[BDNF]] Polymorphisms on Transfer Effects Following Multi- and Single-Domain Cognitive Training Among Community-Dwelling Shanghainese Older Adults.
|date=12.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26318747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30026692
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648978
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041383
}}
}}
* {{medline-title
* {{medline-title
|title=Role of macrophage migration inhibitory factor in age-related lung disease.
|title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.
|date=01.07.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25957294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481
}}
}}
* {{medline-title
* {{medline-title
|title=Macrophage migration inhibitory factor confers resistance to senescence through [[CD74]]-dependent AMPK-FOXO3a signaling in mesenchymal stem cells.
|title=Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.
|date=22.04.2015
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25896286
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29637543
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105503
}}
}}
* {{medline-title
* {{medline-title
|title=Role of macrophage migration inhibitory factor in age-related hearing loss.
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=24.10.2014
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25194790
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2014.08.042
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
* {{medline-title
|title=Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease.
|date=15.03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24441872
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949087
}}
}}
==MMP13==
==CTRL==


* {{medline-title
* {{medline-title
|title=Aging aggravates intervertebral disc degeneration by regulating transcription factors toward chondrogenesis.
|title=Aging reduces the maximal level of peripheral fatigue tolerable and impairs exercise capacity.
|date=02.2020
|date=01.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31909538
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32966120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018543
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00151.2020
}}
}}
* {{medline-title
* {{medline-title
|title=[[EGR1]] promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling.
|title=miR-146a Plasma Levels Are Not Altered in Alzheimer's Disease but Correlate With Age and Illness Severity.
|date=01.09.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201921
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32009940
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.06.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978630
}}
}}
* {{medline-title
* {{medline-title
|title=Chondrocyte-Specific [[RUNX2]] Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice.
|title=Centrally-mediated regulation of peripheral fatigue during knee extensor exercise and consequences on the force-duration relationship in older men.
|date=09.2019
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31397211
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047611
|full-text-url=https://sci-hub.do/10.1080/17461391.2019.1655099
}}
}}
* {{medline-title
* {{medline-title
|title=TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
|title=Non-linear registration improves statistical power to detect hippocampal atrophy in aging and dementia.
|date=08.05.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31068441
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31233953
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102613
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595082
}}
}}
* {{medline-title
* {{medline-title
|title=Systemic clearance of p16  -positive senescent cells mitigates age-associated intervertebral disc degeneration.
|title=Plyometric exercise improves jumping performance and skeletal muscle contractile properties in seniors.
|date=06.2019
|date=01.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30900385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30839302
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516165
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454255
}}
}}
* {{medline-title
* {{medline-title
|title=Design, cyclization, and optimization of [[MMP13]]-[[TIMP1]] interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis.
|title=Soy isoflavones protect against oxidative stress and diminish apoptosis in ovary of middle-aged female rats.
|date=01.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352228
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784335
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.10.141
|full-text-url=https://sci-hub.do/10.1080/09513590.2018.1559287
}}
}}
* {{medline-title
* {{medline-title
|title=Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells.
|title=Heterogeneity of Thyroid Function and Impact of Peripheral Thyroxine Deiodination in Centenarians and Semi-Supercentenarians: Association With Functional Status and Mortality.
|date=12.2017
|date=16.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165411
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755030
|full-text-url=https://sci-hub.do/10.1093/gerona/gly194
}}
}}
* {{medline-title
* {{medline-title
|title=Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritis chondrocytes.
|title=Evaluation of Lymphocyte Response to the Induced Oxidative Stress in a Cohort of Ageing Subjects, including Semisupercentenarians and Their Offspring.
|date=16.09.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28728848
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29681767
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.07.094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842690
}}
}}
==CXCL12==
* {{medline-title
* {{medline-title
|title=Differential Matrix Metalloprotease (MMP) Expression Profiles Found in Aged Gingiva.
|title=Co-option of Neutrophil Fates by Tissue Environments.
|date=2016
|date=25.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33098771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938517
|full-text-url=https://sci-hub.do/10.1016/j.cell.2020.10.003
}}
}}
==MSTN==
* {{medline-title
* {{medline-title
|title=Age- and stage-dependent variations of muscle-specific gene expression in brown trout Salmo trutta L.
|title=Heme oxygenase-1 deficiency triggers exhaustion of hematopoietic stem cells.
|date=09.2017
|date=05.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28408166
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31885181
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2017.04.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7001511
}}
}}
* {{medline-title
* {{medline-title
|title=Activity of metabolic enzymes and muscle-specific gene expression in parr and smolts Atlantic salmon Salmo salar L. of different age groups.
|title=Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation.
|date=08.2017
|date=03.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28315163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31801092
|full-text-url=https://sci-hub.do/10.1007/s10695-017-0357-0
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.11.004
}}
}}
* {{medline-title
* {{medline-title
|title=miR-30e is negatively regulated by myostatin in skeletal muscle and is functionally related to fiber-type composition.
|title=Long-term repopulation of aged bone marrow stem cells using young Sca-1 cells promotes aged heart rejuvenation.
|date=01.05.2017
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28338991
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385396
|full-text-url=https://sci-hub.do/10.1093/abbs/gmx019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826122
}}
}}
* {{medline-title
* {{medline-title
|title=Muscle-Related Polymorphisms ([[MSTN]] rs1805086 and [[ACTN3]] rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians.
|title=Reducing [[CXCR4]] Resulted in Impairing Proliferation and Promoting Aging.
|date=2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27861536
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30080220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115755
|full-text-url=https://sci-hub.do/10.1007/s12603-018-1013-9
}}
}}
* {{medline-title
* {{medline-title
|title=Temporal and spatial expression of Smads and their correlation with [[YAP1]] expression in sheep.
|title=Quantitative spatial analysis of haematopoiesis-regulating stromal cells in the bone marrow microenvironment by 3D microscopy.
|date=26.08.2016
|date=28.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27706608
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955044
|full-text-url=https://sci-hub.do/10.4238/gmr.15037715
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023894
}}
}}
* {{medline-title
* {{medline-title
|title=Quantification of [[GDF11]] and Myostatin in Human Aging and Cardiovascular Disease.
|title=Tumor microenvironment in functional adrenocortical adenomas: immune cell infiltration in cortisol-producing adrenocortical adenoma.
|date=14.06.2016
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27304512
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596893
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913514
|full-text-url=https://sci-hub.do/10.1016/j.humpath.2018.03.016
}}
}}
* {{medline-title
* {{medline-title
|title=Morphological analysis and muscle-associated gene expression during different muscle growth phases of Megalobrama amblycephala.
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|date=28.09.2015
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26436405
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|full-text-url=https://sci-hub.do/10.4238/2015.September.28.16
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
}}
}}
==ERF==
* {{medline-title
* {{medline-title
|title=The effect of exercise mode on the acute response of satellite cells in old men.
|title=Angiotensin-Converting Enzyme Gene D/I Polymorphism in Relation to Endothelial Function and Endothelial-Released Factors in Chinese Women.
|date=12.2015
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26367861
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33041838
|full-text-url=https://sci-hub.do/10.1111/apha.12601
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526498
}}
}}
* {{medline-title
* {{medline-title
|title=Haploinsufficiency of myostatin protects against aging-related declines in muscle function and enhances the longevity of mice.
|title=Projections of Ambient Temperature- and Air Pollution-Related Mortality Burden Under Combined Climate Change and Population Aging Scenarios: a Review.
|date=08.2015
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25808276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32542573
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531085
|full-text-url=https://sci-hub.do/10.1007/s40572-020-00281-6
}}
}}
==PER2==
* {{medline-title
* {{medline-title
|title=NAD  Controls Circadian Reprogramming through [[PER2]] Nuclear Translocation to Counter Aging.
|title=Exome Sequencing Analysis Identifies Rare Variants in [i]ATM[/i] and [i]RPL8[/i] That Are Associated With Shorter Telomere Length.
|date=04.06.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32369735
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32425970
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275919
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204400
}}
}}
* {{medline-title
* {{medline-title
|title=The protective effect of cycloastragenol on aging mouse circadian rhythmic disorder induced by d-galactose.
|title=The [[ERF]] transcription factor EPI1 is a negative regulator of dark-induced and jasmonate-stimulated senescence in [i]Arabidopsis[/i].
|date=10.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31367181
|full-text-url=https://sci-hub.do/10.1002/jcb.28587
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637254
}}
}}
* {{medline-title
* {{medline-title
|title=Investigating circadian clock gene expression in human tendon biopsies from acute exercise and immobilization studies.
|title=Transcriptional regulation of Lonicera japonica Thunb. during flower development as revealed by comprehensive analysis of transcription factors.
|date=06.2019
|date=14.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31088368
|full-text-url=https://sci-hub.do/10.1007/s00421-019-04129-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518806
}}
}}
* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=Impact of Alternatively Polyadenylated Isoforms of ETHYLENE RESPONSE FACTOR4 with Activator and Repressor Function on Senescence in [i]Arabidopsis thaliana[/i] L.
|date=21.11.2018
|date=28.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696119
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409740
}}
}}
* {{medline-title
* {{medline-title
|title=Ontogeny of Circadian Rhythms and Synchrony in the Suprachiasmatic Nucleus.
|title=Transcriptome analysis of leaf senescence in red clover ([i]Trifolium pratense[/i] L.).
|date=07.02.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29054877
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30150852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815340
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103954
}}
}}
* {{medline-title
* {{medline-title
|title=Differential menopause- versus aging-induced changes in oxidative stress and circadian rhythm gene markers.
|title=Molecular and functional characterization of ShNAC1, an NAC transcription factor from Solanum habrochaites.
|date=06.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28408140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29650161
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.04.002
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2018.03.005
}}
}}
==G6PD==
* {{medline-title
* {{medline-title
|title=Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging.
|title=[[G6PD]] overexpression protects from oxidative stress and age-related hearing loss.
|date=27.06.2016
|date=22.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27346580
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33222382
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922021
|full-text-url=https://sci-hub.do/10.1111/acel.13275
}}
}}
* {{medline-title
* {{medline-title
|title=Circadian Clock Control by Polyamine Levels through a Mechanism that Declines with Age.
|title=The Sickle Effect: The Silent Titan Affecting Glycated Hemoglobin Reliability.
|date=03.11.2015
|date=12.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26456331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32923278
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2015.09.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486097
}}
}}
* {{medline-title
* {{medline-title
|title=Local receptors as novel regulators for peripheral clock expression.
|title=DNA damage and synaptic and behavioural disorders in glucose-6-phosphate dehydrogenase-deficient mice.
|date=11.2014
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25145629
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31581069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200324
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812046
}}
}}
==SMAD3==
* {{medline-title
* {{medline-title
|title=Sirtuin 6 deficiency transcriptionally up-regulates TGF-β signaling and induces fibrosis in mice.
|title=JNK modifies neuronal metabolism to promote proteostasis and longevity.
|date=10.01.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31744885
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30810280
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956532
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516429
}}
}}
* {{medline-title
* {{medline-title
|title=Restoring extracellular matrix synthesis in senescent stem cells.
|title=Antioxidant SMe1EC2 modulates pentose phosphate pathway and glutathione-dependent enzyme activities in tissues of aged diabetic rats.
|date=10.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287964
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30147422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766659
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102677
}}
}}
* {{medline-title
* {{medline-title
|title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells.
|title=Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of [[TP53]].
|date=15.07.2019
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941676
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106910
}}
}}
* {{medline-title
* {{medline-title
|title=Histopathological and molecular analysis of idiopathic pulmonary fibrosis lungs from patients treated with pirfenidone or nintedanib.
|title=Safety of Single-Dose Primaquine in [[G6PD]]-Deficient and [[G6PD]]-Normal Males in Mali Without Malaria: An Open-Label, Phase 1, Dose-Adjustment Trial.
|date=01.2019
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30152895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29342267
|full-text-url=https://sci-hub.do/10.1111/his.13745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974787
}}
}}
* {{medline-title
* {{medline-title
|title=Beta-Catenin and [[SMAD3]] Are Associated with Skeletal Muscle Aging in the Taurine Transpoeter Knockout Mouse.
|title=Effect of age, period and birth-cohort on the frequency of glucose-6-phosphate dehydrogenase deficiency in Sardinian adults.
|date=2017
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849477
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28985689
|full-text-url=https://sci-hub.do/10.1007/978-94-024-1079-2_39
|full-text-url=https://sci-hub.do/10.1080/07853890.2017.1390247
}}
}}
==HDAC3==
* {{medline-title
* {{medline-title
|title=[[STAT3]]-mediated [[SMAD3]] activation underlies Oncostatin M-induced Senescence.
|title=Histone deacetylase-3: Friend and foe of the brain.
|date=16.02.2017
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27892764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32486848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324753
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400723
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis.
|title=Loss of [[HDAC3]] contributes to meiotic defects in aged oocytes.
|date=01.05.2017
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27522058
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31498540
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964739
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826132
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.
|title=[[HDAC3]]-Mediated Repression of the [i]Nr4a[/i] Family Contributes to Age-Related Impairments in Long-Term Memory.
|date=08.01.2016
|date=19.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26489925
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31000586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748736
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670247
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of aging on cardiac extracellular matrix in men and women.
|title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke.
|date=01.2016
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26280680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954
|full-text-url=https://sci-hub.do/10.1002/prca.201500031
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016
}}
}}
==SON==
* {{medline-title
 
|title=[[HDAC3]] Regulates the Transition to the Homeostatic Myelinating Schwann Cell State.
* {{medline-title
|date=04.12.2018
|title=Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30517863
|date=01.10.2019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293966
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30861131
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656591
}}
}}
* {{medline-title
* {{medline-title
|title=Neural Mechanisms Involved in the Noxious Physical Stress-Induced Inhibition of Ovarian Estradiol Secretion.
|title=Novel anti-aging gene NM_026333 contributes to proton-induced aging via NCX1-pathway.
|date=06.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30730610
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30385152
|full-text-url=https://sci-hub.do/10.1002/ar.24078
|full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2018.10.021
}}
}}
* {{medline-title
* {{medline-title
|title=Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats.
|title=Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory.
|date=01.08.2018
|date=20.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30127461
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019141
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6102273
}}
}}
* {{medline-title
* {{medline-title
|title=The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system.
|title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.
|date=05.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29494864
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771
}}
}}
==IL10==
* {{medline-title
* {{medline-title
|title=Increased oxytocin-monomeric red fluorescent protein 1 fluorescent intensity with urocortin-like immunoreactivity in the hypothalamo-neurohypophysial system of aged transgenic rats.
|title=The beneficial effect of physical exercise on inflammatory makers in older individuals.
|date=03.2018
|date=06.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28859972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32504508
|full-text-url=https://sci-hub.do/10.1016/j.neures.2017.08.001
|full-text-url=https://sci-hub.do/10.2174/1871530320666200606225357
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related (Aged vs. Adult) Comparison of the Effect of Two Mild Stressors on the Nerve Growth Factor ([[NGF]]) in the Rat Hypothalamic Supraoptic Nucleus ([[SON]]) - Immunohistochemical Study.
|title=Astrocyte senescence may drive alterations in GFAPα, CDKN2A p14 , and TAU3 transcript expression and contribute to cognitive decline.
|date=2016
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27978417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654269
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885035
}}
}}
* {{medline-title
* {{medline-title
|title=Exposure to mild stress and brain derived neurotrophin factor ([[BDNF]]) immunoreactivity in the hypothalamic paraventricular (PVN) and supraoptic ([[SON]]) nuclei: Comparison between aged and adult rats.
|title=Dietary Spray-Dried Porcine Plasma Prevents Cognitive Decline in Senescent Mice and Reduces Neuroinflammation and Oxidative Stress.
|date=12.2016
|date=01.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27565677
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562503
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2016.08.007
|full-text-url=https://sci-hub.do/10.1093/jn/nxz239
}}
}}
* {{medline-title
* {{medline-title
|title=Testing the critical window of estradiol replacement on gene expression of vasopressin, oxytocin, and their receptors, in the hypothalamus of aging female rats.
|title=Age-dependent hepatic alterations induced by a high-fat high-fructose diet.
|date=05.01.2016
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26454088
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30874869
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684429
|full-text-url=https://sci-hub.do/10.1007/s00011-019-01223-1
}}
}}
* {{medline-title
* {{medline-title
|title=[Lamellar complex changes in the human basal forebrain and hypothalamic nuclei neurons in different age groups].
|title=[i]Lactobacillus paracasei[/i] PS23 decelerated age-related muscle loss by ensuring mitochondrial function in SAMP8 mice.
|date=2014
|date=29.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25946833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696799
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366975
}}
}}
==SORL1==
* {{medline-title
* {{medline-title
|title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.
|title=Inflammatory cytokines and immune system modulation by aerobic versus resisted exercise training for elderly.
|date=05.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706571
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29977265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016983
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.
|title=Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29715306
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929513
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic epistasis regulates amyloid deposition in resilient aging.
|title=Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia.
|date=10.2017
|date=01.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28322202
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756472
}}
}}
==INS==
* {{medline-title
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|title=Melatonin protects [[INS]]-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity.
|date=11.04.2017
|date=03.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32673151
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527021
}}
}}
* {{medline-title
* {{medline-title
|title=[[SORL1]] rs1699102 polymorphism modulates age-related cognitive decline and gray matter volume reduction in non-demented individuals.
|title=Nicotine triggers islet β cell senescence to facilitate the progression of type 2 diabetes.
|date=01.2017
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27779372
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32473187
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177470
|full-text-url=https://sci-hub.do/10.1016/j.tox.2020.152502
}}
}}
* {{medline-title
* {{medline-title
|title=Sex-specific characterization and evaluation of the Alzheimer's disease genetic risk factor sorl1 in zebrafish during aging and in the adult brain following a 100 ppb embryonic lead exposure.
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading.
|date=04.2017
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27535807
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022
|full-text-url=https://sci-hub.do/10.1002/jat.3372
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of [[SORL1]] genetic variations on MRI markers in non-demented elders.
|title=Insulin-like peptides and the mTOR-[[TFEB]] pathway protect [i]Caenorhabditis elegans[/i] hermaphrodites from mating-induced death.
|date=31.05.2016
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27177090
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697448
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Alzheimer's Disease Risk Variant rs3824968 at [[SORL1]] on Regional Gray Matter Volume and Age-Related Interaction in Adult Lifespan.
|title=The Maghreb demographic transition: Tunisia case study.
|date=21.03.2016
|date=10-11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26996954
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30746669
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800313
 
}}
}}
* {{medline-title
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|title=Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis.
|date=04.2016
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30456853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351846
}}
* {{medline-title
|title=A functional study of all 40 [i]Caenorhabditis elegans[/i] insulin-like peptides.
|date=26.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206121
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204898
}}
}}
==TAZ==
* {{medline-title
* {{medline-title
|title=Transcriptional Coactivator [[TAZ]] Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence.
|title=The anti-aging protein Klotho is induced by GABA therapy and exerts protective and stimulatory effects on pancreatic beta cells.
|date=09.01.2020
|date=02.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31936650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28993191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016652
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.10.029
}}
}}
==KRAS==
* {{medline-title
* {{medline-title
|title=Downregulation of miR-125b promotes resistance of glioma cells to TRAIL through overexpression of Tafazzin which is a mitochondrial protein.
|title=Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging.
|date=05.05.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33067202
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535077
 
}}
}}
* {{medline-title
* {{medline-title
|title=Dysregulation of the Hippo pathway signaling in aging and cancer.
|title=Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
|date=05.2019
|date=16.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30910741
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32234521
|full-text-url=https://sci-hub.do/10.1016/j.phrs.2019.03.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278897
}}
}}
* {{medline-title
* {{medline-title
|title=Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging.
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|date=03.12.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264619
|full-text-url=https://sci-hub.do/10.1002/path.5314
}}
}}
* {{medline-title
* {{medline-title
|title=[[PGC]]-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing [[TAZ]].
|title=Inhibition of ERK1/2 in cancer-associated pancreatic stellate cells suppresses cancer-stromal interaction and metastasis.
|date=02.08.2018
|date=27.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30017591
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31133044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537367
}}
}}
* {{medline-title
* {{medline-title
|title=Transcriptional coactivator with PDZ-binding motif is required to sustain testicular function on aging.
|title=Comprehensive transcriptome profiling in elderly cancer patients reveals aging-altered immune cells and immune checkpoints.
|date=10.2017
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28613007
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30230534
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595677
|full-text-url=https://sci-hub.do/10.1002/ijc.31875
}}
}}
* {{medline-title
* {{medline-title
|title=Mutant p53 Protein and the Hippo Transducers YAP and [[TAZ]]: A Critical Oncogenic Node in Human Cancers.
|title=O-GlcNAcylation is required for mutant [[KRAS]]-induced lung tumorigenesis.
|date=03.05.2017
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28467351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454874
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205381
}}
}}
* {{medline-title
* {{medline-title
|title=Snail/Slug-YAP/[[TAZ]] complexes cooperatively regulate mesenchymal stem cell function and bone formation.
|title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16  and Wild-Type p53.
|date=04.03.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28112996
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351930
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985
}}
}}
* {{medline-title
* {{medline-title
|title=Decreased osteogenesis in mesenchymal stem cells derived from the aged mouse is associated with enhanced NF-κB activity.
|title=[[ARID1A]] suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[[[CDKN2A]]]] regulatory axis.
|date=02.2017
|date=18.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27105133
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942143
|full-text-url=https://sci-hub.do/10.1002/jor.23270
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.099
}}
}}
==TLR7==
==MMP2==


* {{medline-title
* {{medline-title
|title=Bovine Lactoferrin Enhances [[TLR7]]-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D.
|title=Cellular retinoic acid binding protein-II expression and its potential role in skin aging.
|date=2018
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515164
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255898
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461173
}}
}}
* {{medline-title
* {{medline-title
|title=B cell responses to apoptotic cells in MFG-E8-/- mice.
|title=[Effect of saponins extracted from Panax japonicas on inhibiting myocardial fibrosis by TGF-β1/Smad3 signaling pathway in aging rats].
|date=2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30286201
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30593247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171925
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180724.006
}}
}}
* {{medline-title
* {{medline-title
|title=Small RNAs induce the activation of the pro-inflammatory [[TLR7]] signaling pathway in aged rat kidney.
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|date=10.2017
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28665028
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595700
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
}}
}}
* {{medline-title
* {{medline-title
|title=Aging effects on T-bet expression in human B cell subsets.
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|date=11.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28457482
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|full-text-url=https://sci-hub.do/10.1016/j.cellimm.2017.04.007
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes and distribution of T cell markers (CD3 and [[CD4]]) and toll-like receptors(TLR2, [[TLR3]],[[TLR4]] and [[TLR7]]) in the duck lymphoid organs.
|title=PM2.5 promotes abdominal aortic aneurysm formation in angiotensin Ⅱ-infused apoe-/- mice.
|date=07.2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356195
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29800919
|full-text-url=https://sci-hub.do/10.1016/j.imbio.2017.01.004
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.04.107
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated B cells: key mediators of both protective and autoreactive humoral responses.
|title=Activation of DNA demethylases attenuates aging-associated arterial stiffening and hypertension.
|date=01.2016
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26683149
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659128
|full-text-url=https://sci-hub.do/10.1111/imr.12380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052484
}}
}}
* {{medline-title
* {{medline-title
|title=Aging Impairs the Ability of Conventional Dendritic Cells to Cross-Prime CD8  T Cells upon Stimulation with a [[TLR7]] Ligand.
|title=[[MMP2]]-[[A2M]] interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction.
|date=2015
|date=19.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26474053
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29464020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814160
}}
}}
* {{medline-title
* {{medline-title
|title=Topical treatment of basal cell carcinoma with the immune response modifier imiquimod.
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|date=11.2015
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26450707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|full-text-url=https://sci-hub.do/10.2217/fon.15.192
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
}}
* {{medline-title
|title=Bacteria and Toll-like receptor and cytokine mRNA expression profiles associated with canine arthritis.
|date=15.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24856731
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2014.04.004
}}
}}
==BMP4==
==MTOR==


* {{medline-title
* {{medline-title
|title=Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome.
|title=The roles of [[MTOR]] and miRNAs in endothelial cell senescence.
|date=08.09.2020
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32896271
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32246301
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478891
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09876-w
}}
}}
* {{medline-title
* {{medline-title
|title=Interplay between Follistatin, Activin A, and [[BMP4]] Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging.
|title=Autophagy drives fibroblast senescence through [[MTOR]]C2 regulation.
|date=25.06.2019
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31931659
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.05.045
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595590
}}
}}
* {{medline-title
* {{medline-title
|title=Centenarians Overexpress Pluripotency-Related Genes.
|title=The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.
|date=16.08.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31795790
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
|full-text-url=https://sci-hub.do/10.1080/15548627.2019.1695399
}}
}}
* {{medline-title
* {{medline-title
|title=BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence.
|title=The double-edged sword of [[MTOR]] in autophagy deficiency induced-liver injury and tumorigenesis.
|date=15.11.2016
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27794120
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31216956
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693464
}}
}}
* {{medline-title
* {{medline-title
|title=Increased bone morphogenetic protein signaling contributes to age-related declines in neurogenesis and cognition.
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=02.2016
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26827654
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
* {{medline-title
* {{medline-title
|title=Control of the Normal and Pathological Development of Neural Stem and Progenitor Cells by the PC3/Tis21/Btg2 and Btg1 Genes.
|title=Effect of young exosomes injected in aged mice.
|date=12.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25967096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30254438
|full-text-url=https://sci-hub.do/10.1002/jcp.25038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141108
}}
}}
* {{medline-title
* {{medline-title
|title=FSH-FSHR3-stem cells in ovary surface epithelium: basis for adult ovarian biology, failure, aging, and cancer.
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=01.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25269615
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://sci-hub.do/10.1530/REP-14-0220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular cloning and expression analysis of prostaglandin E receptor 2 gene in cashmere goat (Capra hircus) skin during hair follicle development.
|title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107.
|date=03.04.2014
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24555795
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052
|full-text-url=https://sci-hub.do/10.1080/10495398.2013.826236
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016
}}
}}
==CCL4==
==MYB==


* {{medline-title
* {{medline-title
|title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau.
|title=Transcriptome profiling of postharvest shoots identifies PheNAP2- and PheNAP3-promoted shoot senescence.
|date=03.09.2018
|date=01.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082275
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31595958
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978
|full-text-url=https://sci-hub.do/10.1093/treephys/tpz100
}}
}}
* {{medline-title
* {{medline-title
|title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles.
|title=Systematic Analysis of [[MYB]] Family Genes in Potato and Their Multiple Roles in Development and Stress Responses.
|date=05.2018
|date=30.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31366107
|full-text-url=https://sci-hub.do/10.1620/tjem.245.29
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723670
}}
}}
* {{medline-title
* {{medline-title
|title=Human Body Composition and Immunity: Visceral Adipose Tissue Produces IL-15 and Muscle Strength Inversely Correlates with NK Cell Function in Elderly Humans.
|title=Transcriptional regulation of Lonicera japonica Thunb. during flower development as revealed by comprehensive analysis of transcription factors.
|date=2018
|date=14.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29559978
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31088368
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845694
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518806
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|title=Transgenic expression of rice [[MYB]]102 (Os[[MYB]]102) delays leaf senescence and decreases abiotic stress tolerance in Arabidopsis thaliana.
|date=2018
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31072449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889895
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A  receptor.
|title=The WRKY transcription factor GhWRKY27 coordinates the senescence regulatory pathway in upland cotton (Gossypium hirsutum L.).
|date=18.10.2017
|date=29.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29064819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680557
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440019
}}
}}
* {{medline-title
* {{medline-title
|title=Simultaneous time course analysis of multiple markers based on DNA microarray in incised wound in skeletal muscle for wound aging.
|title=Rice transcription factor Os[[MYB]]102 delays leaf senescence by down-regulating abscisic acid accumulation and signaling.
|date=09.2016
|date=09.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27376479
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30825376
|full-text-url=https://sci-hub.do/10.1016/j.forsciint.2016.06.027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506775
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in the expression of the Toll-like receptor system in the aging rat kidneys.
|title=Transcriptome analysis of leaf senescence in red clover ([i]Trifolium pratense[/i] L.).
|date=2014
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30150852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014502
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103954
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related brain expression and regulation of the chemokine [[CCL4]]/MIP-1β in APP/PS1 double-transgenic mice.
|title=The Direct Involvement of Dark-Induced Tic55 Protein in Chlorophyll Catabolism and Its Indirect Role in the [[MYB]]108-NAC Signaling Pathway during Leaf Senescence in [i]Arabidopsis thaliana[/i].
|date=04.2014
|date=23.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24607962
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29937503
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977177
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073118
}}
}}
==CD163==
==NQO1==


* {{medline-title
* {{medline-title
|title=Complement Inhibition Attenuates Early Erythrolysis in the Hematoma and Brain Injury in Aged Rats.
|title=Augmentation of cellular NAD  by [[NQO1]] enzymatic action improves age-related hearing impairment.
|date=07.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31177985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31353811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591097
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718544
}}
}}
* {{medline-title
* {{medline-title
|title=Increased monocyte activation with age among HIV-infected long term non-progressor children: implications for early treatment initiation.
|title=Well-aging: A new strategy for skin homeostasis under multi-stressed conditions.
|date=09.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31131542
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31232507
|full-text-url=https://sci-hub.do/10.1111/hiv.12751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003805
}}
}}
* {{medline-title
* {{medline-title
|title=Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
|title=Limitations to adaptive homeostasis in an hyperoxia-induced model of accelerated ageing.
|date=2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31022673
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479762
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related M1/M2 phenotype changes in circulating monocytes from healthy/unhealthy individuals.
|title=Link between cardiac function and the antioxidative defense mechanism in aged rats.
|date=08.06.2018
|date=11.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29885276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31010674
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046240
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.03.182
}}
}}
* {{medline-title
* {{medline-title
|title=Distinct effect of age, sex, and CMV seropositivity on dendritic cells and monocytes in human blood.
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats].
|date=01.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29359459
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111059
|full-text-url=https://sci-hub.do/10.1111/imcb.1004
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180408.005
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-related effects of bed rest followed by eccentric exercise rehabilitation on skeletal muscle macrophages and insulin sensitivity.
|title=Benefits of Caloric Restriction in Longevity and Chemical-Induced Tumorigenesis Are Transmitted Independent of [[NQO1]].
|date=01.07.2018
|date=16.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28705613
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733330
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762440
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599277
}}
}}
* {{medline-title
* {{medline-title
|title=[Signal molecules of endometrium: gerontological and general pathhological aspects].
|title=Overexpression of [[CYB5R3]] and [[NQO1]], two NAD  -producing enzymes, mimics aspects of caloric restriction.
|date=2015
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28509480
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706024
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052403
}}
}}
* {{medline-title
* {{medline-title
|title=Myocardial Infarction Superimposed on Aging: MMP-9 Deletion Promotes M2 Macrophage Polarization.
|title=Sargassum fusiforme Polysaccharide Rejuvenat es the Small Intestine in Mice Through Altering its Physiol ogy and Gut Microbiota Composition.
|date=04.2016
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25878031
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29210649
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175450
|full-text-url=https://sci-hub.do/10.2174/1566524018666171205115516
}}
}}
==CD2==
==PIP==


* {{medline-title
* {{medline-title
|title=Adaptive NKG2C CD57  Natural Killer Cell and Tim-3 Expression During Viral Infections.
|title=Potentially inappropriate prescriptions according to explicit and implicit criteria in patients with multimorbidity and polypharmacy. MULTIPAP: A cross-sectional study.
|date=2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731749
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32785232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919961
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7423095
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|title=Quality of prescribing predicts hospitalisation in octogenarians: life and living in advanced age: a cohort study in New Zealand (LiLACS NZ).
|date=12.2017
|date=19.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31856733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921419
}}
}}
* {{medline-title
* {{medline-title
|title=Tumor-host signaling interaction reveals a systemic, age-dependent splenic immune influence on tumor development.
|title=A Systematic Review of Studies of the STOPP/START 2015 and American Geriatric Society Beers 2015 Criteria in Patients ≥ 65 Years.
|date=03.11.2015
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26497558
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31096900
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742115
|full-text-url=https://sci-hub.do/10.2174/1874609812666190516093742
}}
}}
* {{medline-title
* {{medline-title
|title=Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age.
|title=Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension.
|date=2015
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26241743
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109455
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524632
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.08.027
}}
}}
* {{medline-title
* {{medline-title
|title=Activation-induced and damage-induced cell death in aging human T cells.
|title=Medicinal products for geriatric patients in Germany : Current status of regulatory requirements and clinical reality.
|date=11.2015
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25843236
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31041579
|full-text-url=https://sci-hub.do/10.1016/j.mad.2015.03.011
|full-text-url=https://sci-hub.do/10.1007/s00391-019-01550-2
}}
}}
* {{medline-title
* {{medline-title
|title=White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke.
|title=Patterns of multi-morbidity and prediction of hospitalisation and all-cause mortality in advanced age.
|date=10.2015
|date=01.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25836044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29281041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591088
|full-text-url=https://sci-hub.do/10.1093/ageing/afx184
}}
}}
* {{medline-title
* {{medline-title
|title=The impact of immunosenescence on humoral immune response variation after influenza A/H1N1 vaccination in older subjects.
|title=A Pharmacist-Led Program to Evaluate and Reduce Polypharmacy and Potentially Inappropriate Prescribing in Older HIV-Positive Patients.
|date=2015
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25816015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29023938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376784
|full-text-url=https://sci-hub.do/10.1002/phar.2043
}}
}}
* {{medline-title
* {{medline-title
|title=Therapeutic efficacy of bone marrow-derived mononuclear cells in diabetic polyneuropathy is impaired with aging or diabetes.
|title=Prevalence and predictors of potentially inappropriate prescribing of central nervous system and psychotropic drugs among elderly patients: A national population study in Korea.
|date=03.2015
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25802721
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28917110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364848
|full-text-url=https://sci-hub.do/10.1016/j.archger.2017.08.013
}}
}}
==CD63==
==PML==


* {{medline-title
* {{medline-title
|title=Cellular senescence contributes to age-dependent changes in circulating extracellular vesicle cargo and function.
|title=Progressive multifocal leukoencephalopathy in dimethyl fumarate-treated multiple sclerosis patients.
|date=03.2020
|date=18.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31960578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32808554
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059145
|full-text-url=https://sci-hub.do/10.1177/1352458520949158
}}
}}
* {{medline-title
* {{medline-title
|title=Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging.
|title=[[PML]]2-mediated thread-like nuclear bodies mark late senescence in Hutchinson-Gilford progeria syndrome.
|date=01.09.2019
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220525
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32351002
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294779
}}
}}
* {{medline-title
* {{medline-title
|title=Adiponectin promotes muscle regeneration through binding to T-cadherin.
|title=Trophoblast type-specific expression of senescence markers in the human placenta.
|date=09.01.2019
|date=15.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30626897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327484
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327035
|full-text-url=https://sci-hub.do/10.1016/j.placenta.2019.06.377
}}
}}
* {{medline-title
* {{medline-title
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.
|title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair.
|date=2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001
}}
}}
* {{medline-title
* {{medline-title
|title=The Aging Process Alters IL-1β and [[CD63]] Levels Differently in Extracellular Vesicles Obtained from the Plasma and Cerebrospinal Fluid.
|title=Nuclear Nox4 interaction with prelamin A is associated with nuclear redox control of stem cell aging.
|date=2018
|date=24.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362963
|full-text-url=https://sci-hub.do/10.1159/000488943
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224265
}}
}}
* {{medline-title
* {{medline-title
|title=miRNA in Circulating Microvesicles as Biomarkers for Age-Related Cognitive Decline.
|title=Aging and lymphocyte changes by immunomodulatory therapies impact [[PML]] risk in multiple sclerosis patients.
|date=2017
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29046635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013383
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating extracellular vesicles in the aging process: impact of aerobic exercise.
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|date=03.2018
|date=28.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28819811
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|full-text-url=https://sci-hub.do/10.1007/s11010-017-3160-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA-183-5p Increases with Age in Bone-Derived Extracellular Vesicles, Suppresses Bone Marrow Stromal (Stem) Cell Proliferation, and Induces Stem Cell Senescence.
|title=Age as a risk factor for early onset of natalizumab-related progressive multifocal leukoencephalopathy.
|date=11.2017
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28363268
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689127
|full-text-url=https://sci-hub.do/10.1007/s13365-017-0561-9
}}
}}
==CDA==
==S100A9==


* {{medline-title
* {{medline-title
|title=Cumulative Dis/Advantage and Health Pattern in Late Life: A Comparison between Genders and Welfare State Regimes.
|title=Cigarette smoke induction of [[S100A9]] contributes to chronic obstructive pulmonary disease.
|date=2019
|date=23.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32964723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367435
|full-text-url=https://sci-hub.do/10.1152/ajplung.00207.2020
}}
}}
* {{medline-title
* {{medline-title
|title=Does numerical similarity alter age-related distractibility in working memory?
|title=Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations.
|date=2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31483830
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32469975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259601
}}
}}
* {{medline-title
* {{medline-title
|title=Can working memory capacity be expanded by boosting working memory updating efficiency in older adults?
|title=Cellular senescence induced by [[S100A9]] in mesenchymal stromal cells through NLRP3 inflammasome activation.
|date=12.2018
|date=14.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30475011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31727865
|full-text-url=https://sci-hub.do/10.1037/pag0000311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874461
}}
}}
* {{medline-title
* {{medline-title
|title=Negative Affect Influences Electrophysiological Markers of Visual Working Memory in Mildly Stressed Older Adults.
|title=[[S100A9]] extends lifespan in insulin deficiency.
|date=2018
|date=07.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29872391
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31391467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686003
}}
}}
* {{medline-title
* {{medline-title
|title=EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development.
|title=[[S100A8]], which increases with age, induces cellular senescence-like changes in bovine oviduct epithelial cells.
|date=02.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175710
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237976
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.10.018
|full-text-url=https://sci-hub.do/10.1111/aji.13163
}}
}}
* {{medline-title
* {{medline-title
|title=Mini dental assessment: a simple screening test for non-dental staff.
|title=Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model.
|date=06.2017
|date=06.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27401181
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991479
|full-text-url=https://sci-hub.do/10.1007/s00784-016-1906-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078409
}}
}}
* {{medline-title
* {{medline-title
|title=Electrophysiological Correlates of Subitizing in Healthy Aging.
|title=Intranasally Administered [[S100A9]] Amyloids Induced Cellular Stress, Amyloid Seeding, and Behavioral Impairment in Aged Mice.
|date=2015
|date=20.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26098959
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29618200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476746
|full-text-url=https://sci-hub.do/10.1021/acschemneuro.7b00512
}}
}}
* {{medline-title
* {{medline-title
|title=Understanding age-related reductions in visual working memory capacity: examining the stages of change detection.
|title=[[S100A9]] Protein Aggregates Boost Hippocampal Glutamate Modifying Monoaminergic Neurochemistry: A Glutamate Antibody Sensitive Outcome on Alzheimer-like Memory Decline.
|date=10.2014
|date=21.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24420648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29160692
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098047
|full-text-url=https://sci-hub.do/10.1021/acschemneuro.7b00379
}}
}}
==CRH==
==SFN==


* {{medline-title
* {{medline-title
|title=Roles of peptides and steroids in sleep disorders.
|title=The phytoprotective agent sulforaphane prevents inflammatory degenerative diseases and age-related pathologies via Nrf2-mediated hormesis.
|date=09.2006
|date=04.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30754093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33160067
|full-text-url=https://sci-hub.do/10.1586/17446651.1.5.609
|full-text-url=https://sci-hub.do/10.1016/j.phrs.2020.105283
}}
}}
* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice.
|date=15.11.2018
|date=29.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33003447
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599699
}}
}}
* {{medline-title
* {{medline-title
|title=Caenorhabditis elegans respond to high-glucose diets through a network of stress-responsive transcription factors.
|title=Sulforaphane controls the release of paracrine factors by keratinocytes and thus mitigates particulate matter-induced premature skin aging by suppressing melanogenesis and maintaining collagen homeostasis.
|date=2018
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039004
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2020.153276
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Sulforaphane Inhibits Autophagy and Induces Exosome-Mediated Paracrine Senescence via Regulating mTOR/TFE3.
|date=12.2017
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32476238
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://sci-hub.do/10.1002/mnfr.201901231
}}
}}
* {{medline-title
* {{medline-title
|title=A C. elegans Thermosensory Circuit Regulates Longevity through crh-1/CREB-Dependent flp-6 Neuropeptide Signaling.
|title=Effects of sulforaphane on D-galactose-induced liver aging in rats: Role of keap-1/nrf-2 pathway.
|date=24.10.2016
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27720609
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039346
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2016.08.021
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2019.04.043
}}
}}
* {{medline-title
* {{medline-title
|title=Variation in the corticotropin-releasing hormone receptor 1 ([[CRH]]R1) gene modulates age effects on working memory.
|title=Sulforaphane - role in aging and neurodegeneration.
|date=02.2015
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25541005
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30941620
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2014.12.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885086
}}
}}
* {{medline-title
* {{medline-title
|title=HPA axis and aging in depression: systematic review and meta-analysis.
|title=The secretory phenotype of senescent astrocytes isolated from Wistar newborn rats changes with anti-inflammatory drugs, but does not have a short-term effect on neuronal mitochondrial potential.
|date=03.2014
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24495607
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097900
|full-text-url=https://sci-hub.do/10.1016/j.psyneuen.2013.12.004
|full-text-url=https://sci-hub.do/10.1007/s10522-018-9767-3
}}
}}
* {{medline-title
* {{medline-title
|title=Regulation of corticosterone secretion is modified by PFOS exposure at different levels of the hypothalamic-pituitary-adrenal axis in adult male rats.
|title=Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress.
|date=15.10.2014
|date=26.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24440345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29074861
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2014.01.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658327
}}
}}
==CYP2C19==
==SST==


* {{medline-title
* {{medline-title
|title=Physiologically Based Pharmacokinetic Approach Can Successfully Predict Pharmacokinetics of Citalopram in Different Patient Populations.
|title=The distance to death perceptions of older adults explain why they age in place: A theoretical examination.
|date=04.2020
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31750550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32972627
|full-text-url=https://sci-hub.do/10.1002/jcph.1541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489887
}}
}}
* {{medline-title
* {{medline-title
|title=Longitudinal exposure of English primary care patients to pharmacogenomic drugs: An analysis to inform design of pre-emptive pharmacogenomic testing.
|title=Population Segmentation Based on Healthcare Needs: Validation of a Brief Clinician-Administered Tool.
|date=12.2019
|date=30.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31454087
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32607929
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955399
|full-text-url=https://sci-hub.do/10.1007/s11606-020-05962-4
}}
}}
* {{medline-title
* {{medline-title
|title=The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers.
|title=Examination on how emotion regulation mediates the relationship between future time perspective and well-being: a counter-evidence to the socioemotional selectivity theory.
|date=05.2018
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567399
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158369
|full-text-url=https://sci-hub.do/10.1016/j.euroneuro.2018.01.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040126
}}
}}
* {{medline-title
* {{medline-title
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
|title=Shear-Wave and Strain Ultrasound Elastography of the Supraspinatus and Infraspinatus Tendons in Patients with Idiopathic Adhesive Capsulitis of the Shoulder: A Prospective Case-Control Study.
|date=12.2017
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31270981
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609436
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits.
|title=Counting down while time flies: implications of age-related time acceleration for goal pursuit across adulthood.
|date=06.2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396010
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048830
|full-text-url=https://sci-hub.do/10.1016/j.ijheh.2017.03.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436994
}}
}}
* {{medline-title
* {{medline-title
|title=Determination of Human Hepatic [[CYP2C8]] and [[CYP1A2]] Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages.
|title=Relative costs and benefits of alternative reproductive phenotypes at different temperatures - genotype-by-environment interactions in a sexually selected trait.
|date=05.2017
|date=11.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28228413
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29996775
|full-text-url=https://sci-hub.do/10.1124/dmd.116.074583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042425
}}
}}
* {{medline-title
* {{medline-title
|title=Identifying clinically relevant sources of variability: The clopidogrel challenge.
|title=Climate change and functional traits affect population dynamics of a long-lived seabird.
|date=02.2017
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27557470
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29931768
|full-text-url=https://sci-hub.do/10.1002/cpt.459
|full-text-url=https://sci-hub.do/10.1111/1365-2656.12827
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of age on serum concentrations of venlafaxine and escitalopram in different [[CYP2D6]] and [[CYP2C19]] genotype subgroups.
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography.
|date=08.2014
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24858822
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483
|full-text-url=https://sci-hub.do/10.1007/s00228-014-1696-8
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0
}}
}}
==DCC==
==STAT1==


* {{medline-title
* {{medline-title
|title=X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation.
|title=[[STAT1]]-p53-p21axis-dependent stress-induced progression of chronic nephrosis in adriamycin-induced mouse model.
|date=21.10.2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31495695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32953802
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810858
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7475511
}}
}}
* {{medline-title
* {{medline-title
|title=Dynamic functional connectivity analysis of functional MRI based on copula time-varying correlation.
|title=Age-Dependent and -Independent Effects of Perivascular Adipose Tissue and Its Paracrine Activities during Neointima Formation.
|date=15.07.2019
|date=31.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31100293
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31906225
|full-text-url=https://sci-hub.do/10.1016/j.jneumeth.2019.05.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981748
}}
}}
* {{medline-title
* {{medline-title
|title=Comprehensive outpatient rehabilitation increases the ability of people over 60 to live independently.
|title=Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/[[STAT1]] activation.
|date=20.12.2018
|date=01.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30586960
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31857155
|full-text-url=https://sci-hub.do/10.26444/aaem/99642
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2019.12.013
}}
}}
* {{medline-title
* {{medline-title
|title=Mesocorticolimbic Connectivity and Volumetric Alterations in [i][[DCC]][/i] Mutation Carriers.
|title=Inflammaging: Age and Systemic, Cellular, and Nuclear Inflammatory Biology in Older Adults.
|date=16.05.2018
|date=04.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712788
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31107949
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956985
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777092
}}
}}
* {{medline-title
* {{medline-title
|title=Dcc haploinsufficiency regulates dopamine receptor expression across postnatal lifespan.
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|date=27.03.2017
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28108253
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337141
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
}}
}}
* {{medline-title
* {{medline-title
|title=Potential effect of mechano growth factor E-domain peptide on axonal guidance growth in primary cultured cortical neurons of rats.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=01.2018
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27863093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1002/term.2364
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
* {{medline-title
* {{medline-title
|title=Mouse genome-wide association study identifies polymorphisms on chromosomes 4, 11, and 15 for age-related cardiac fibrosis.
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|date=06.2016
|date=14.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27126641
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235362
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic Analysis of Protein Expression Throughout Disease Progression in a Mouse Model of Alzheimer's Disease.
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|date=2015
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26401771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|full-text-url=https://sci-hub.do/10.3233/JAD-150312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
}}
}}
==DES==
==ULK1==


* {{medline-title
* {{medline-title
|title=Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis.
|title=[Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/[[ULK1]] signaling activation].
|date=20.03.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29558926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989992
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859529
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20181205.001
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic variation in low-dose effects of neonatal [[DES]] exposure in female rats.
|title=The autophagy-related gene [i]Atg101[/i] in [i]Drosophila[/i] regulates both neuron and midgut homeostasis.
|date=10.2017
|date=05.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28734970
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760524
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2017.07.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462509
}}
}}
* {{medline-title
* {{medline-title
|title=Aging Eye Microbiota in Dry Eye Syndrome in Patients Treated with [i]Enterococcus faecium[/i] and [i]Saccharomyces boulardii[/i].
|title=Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-[[ULK1]] signaling-mediated autophagy.
|date=2017
|date=24.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585174
|full-text-url=https://sci-hub.do/10.2174/1574884712666170704145046
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326678
}}
}}
* {{medline-title
* {{medline-title
|title=The influence of advancing age on implantation of drug-eluting stents.
|title=Sarcopenia targeting with autophagy mechanism by exercise.
|date=10.2016
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26603135
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526769
|full-text-url=https://sci-hub.do/10.1002/ccd.26333
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386226
}}
}}
* {{medline-title
* {{medline-title
|title=Calculating when elective abdominal aortic aneurysm repair improves survival for individual patients: development of the Aneurysm Repair Decision Aid and economic evaluation.
|title=Young plasma attenuates age-dependent liver ischemia reperfusion injury.
|date=04.2015
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25924187
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30383439
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781543
|full-text-url=https://sci-hub.do/10.1096/fj.201801234R
}}
}}
* {{medline-title
* {{medline-title
|title=Diethylstilbestrol exposure in neonatal mice induces changes in the adulthood in the immune response to taenia crassiceps without modifications of parasite loads.
|title=Depletion of gamma-glutamylcyclotransferase in cancer cells induces autophagy followed by cellular senescence.
|date=2014
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25243144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29736310
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934555
}}
}}
* {{medline-title
* {{medline-title
|title=Androgen deficiency and dry eye syndrome in the aging male.
|title=Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells.
|date=03.07.2014
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24994872
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132553
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989724
}}
}}
* {{medline-title
* {{medline-title
|title=[[[DES]] Daughter--expertise remains necessary].
|title=Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-[[ULK1]] signaling pathway.
|date=2013
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24382040
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344647
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810242
}}
}}
==EDA==
==ATF6==


* {{medline-title
* {{medline-title
|title=Interplay between aging, lung inflammation/remodeling, and fibronectin [[EDA]] in lung cancer progression.
|title=Cellular proteostasis decline in human senescence.
|date=01.12.2020
|date=30.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33222614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33257563
|full-text-url=https://sci-hub.do/10.1080/15384047.2020.1831372
|full-text-url=https://sci-hub.do/10.1073/pnas.2018138117
}}
}}
* {{medline-title
* {{medline-title
|title=Arousal Detection in Elderly People from Electrodermal Activity Using Musical Stimuli.
|title=Impact of endoplasmic reticulum stress on oocyte aging mechanisms.
|date=25.08.2020
|date=01.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32854302
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32514562
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506973
|full-text-url=https://sci-hub.do/10.1093/molehr/gaaa040
}}
}}
* {{medline-title
* {{medline-title
|title=The structure of agricultural microplastics (PT, PU and UF) and their sorption capacities for PAHs and PHE derivates under various salinity and oxidation treatments.
|title=ER stress activates immunosuppressive network: implications for aging and Alzheimer's disease.
|date=02.2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31761592
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32279085
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2019.113525
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220864
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of storage on quality parameters and phenolic content of Italian extra-virgin olive oils.
|title=Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes.
|date=01.2020
|date=21.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30896291
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31972978
|full-text-url=https://sci-hub.do/10.1080/14786419.2019.1587434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072557
}}
}}
* {{medline-title
* {{medline-title
|title=Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice.
|title=Reaction to Endoplasmic Reticulum Stress [i]via[/i] [[ATF6]] in Amyotrophic Lateral Sclerosis Deteriorates With Aging.
|date=03.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326316
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30740050
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823768
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355670
}}
}}
* {{medline-title
* {{medline-title
|title=An Extract from the Plant [i]Deschampsia antarctica[/i] Protects Fibroblasts from Senescence Induced by Hydrogen Peroxide.
|title=[Protective effect of Wuzi Yanzong recipe on testicular germ cell apoptosis in natural ageing rats through endoplasmic reticulum stress].
|date=2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453716
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574316
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180530.001
}}
}}
* {{medline-title
* {{medline-title
|title=Occurrence of fibronectin-fibrin complexes in plasma of patients with multimorbidity due to the inflamm-aging phenomenon.
|title=[[PGC]]-1α in aging and lifelong exercise training-mediated regulation of UPR in mouse liver.
|date=05.2016
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26883337
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28801170
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.02.006
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.006
}}
}}
==ATG5==
* {{medline-title
* {{medline-title
|title=Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy.
|title=Autophagy and heat-shock response impair stress granule assembly during cellular senescence.
|date=09.2015
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26220387
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33049246
|full-text-url=https://sci-hub.do/10.1016/j.eplepsyres.2015.06.005
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111382
}}
}}
==F5==
* {{medline-title
* {{medline-title
|title=Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis.
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models.
|date=02.2020
|date=28.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32039401
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005566
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415
}}
}}
* {{medline-title
* {{medline-title
|title=Fermentation of Blackberry with [i]L. plantarum[/i] JBMI [[F5]] Enhance the Protection Effect on UVB-Mediated Photoaging in Human Foreskin Fibroblast and Hairless Mice through Regulation of MAPK/NF-κB Signaling.
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=11.10.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31614689
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835613
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
* {{medline-title
* {{medline-title
|title=Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing.
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|date=09.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031222
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.07.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
}}
}}
* {{medline-title
* {{medline-title
|title=Multigenerational effects of 4-methylbenzylidene camphor (4-MBC) on the survival, development and reproduction of the marine copepod Tigriopus japonicus.
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=01.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172130
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://sci-hub.do/10.1016/j.aquatox.2017.11.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
}}
* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=Carvacrol nanoemulsion evokes cell cycle arrest, apoptosis induction and autophagy inhibition in doxorubicin resistant-A549 cell line.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29405784
|full-text-url=https://sci-hub.do/10.1080/21691401.2018.1434187
}}
* {{medline-title
|title=Compromised autophagy precedes meniscus degeneration and cartilage damage in mice.
|date=11.2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28801209
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650923
}}
}}
==BCR==
* {{medline-title
* {{medline-title
|title=Sublethal effects of imidacloprid on the fecundity, longevity, and enzyme activity of Sitobion avenae (Fabricius) and Rhopalosiphum padi (Linnaeus).
|title=The presence of CLL-associated stereotypic B cell receptors in the normal [[BCR]] repertoire from healthy individuals increases with age.
|date=08.2016
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27161277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31485252
|full-text-url=https://sci-hub.do/10.1017/S0007485316000286
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714092
}}
}}
* {{medline-title
* {{medline-title
|title=Nutritional habits, lifestyle, and genetic predisposition in cardiovascular and metabolic traits in Turkish population.
|title=Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation.
|date=06.2016
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26856649
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930899
|full-text-url=https://sci-hub.do/10.1016/j.nut.2015.12.027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428705
}}
}}
* {{medline-title
* {{medline-title
|title=[Clinical and genetic characteristics of long-livers in Moscow region].
|title=Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors.
|date=2013
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30487792
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246921
}}
}}
==FGFR1==
* {{medline-title
* {{medline-title
|title=Alignment of Alzheimer's disease amyloid β-peptide and klotho.
|title=B cell responses to apoptotic cells in MFG-E8-/- mice.
|date=11-12.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32999998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30286201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521834
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171925
}}
}}
* {{medline-title
* {{medline-title
|title=Satellite cell-specific ablation of Cdon impairs integrin activation, FGF signalling, and muscle regeneration.
|title=Early Generated B-1-Derived B Cells Have the Capacity To Progress To Become Mantle Cell Lymphoma-like Neoplasia in Aged Mice.
|date=08.2020
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32103583
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432598
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036230
}}
}}
* {{medline-title
* {{medline-title
|title=Systemic administration of a fibroblast growth factor receptor 1 agonist rescues the cognitive deficit in aged socially isolated rats.
|title=Mean residual life regression with functional principal component analysis on longitudinal data for dynamic prediction.
|date=06.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928883
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29601636
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.02.011
|full-text-url=https://sci-hub.do/10.1111/biom.12876
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of aging and caloric restriction on fibroblast growth factor 21 signaling in rat white adipose tissue.
|title=NLR Nod1 signaling promotes survival of [[BCR]]-engaged mature B cells through up-regulated Nod1 as a positive outcome.
|date=04.2019
|date=02.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30620889
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28878001
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626402
}}
}}
==CCL11==
* {{medline-title
* {{medline-title
|title=Activity-dependent neuronal Klotho enhances astrocytic aerobic glycolysis.
|title=CCL-11 or Eotaxin-1: An Immune Marker for Ageing and Accelerated Ageing in Neuro-Psychiatric Disorders.
|date=08.2019
|date=02.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29493420
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32887304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7558796
}}
}}
* {{medline-title
* {{medline-title
|title=Decline in Proliferation and Immature Neuron Markers in the Human Subependymal Zone during Aging: Relationship to [[EGF]]- and FGF-Related Transcripts.
|title=Young bone marrow transplantation preserves learning and memory in old mice.
|date=2016
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27932973
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123444
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382867
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Changes in FGF-2, Fibroblast Growth Factor Receptors and β-Catenin Expression in Human Mesenchyme-Derived Progenitor Cells.
|title=[The role of «Youth and aging proteins» in essential hypertension pathogenesis.]
|date=03.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26332075
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30584875
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861164
 
}}
}}
* {{medline-title
* {{medline-title
|title=A correlation between decreased parathyroid α-Klotho and fibroblast growth factor receptor 1 expression with pathological category and parathyroid gland volume in dialysis patients.
|title=Association between plasma [[CCL11]] (eotaxin-1) and cognitive status in older adults: Differences between rural and urban dwellers.
|date=04.2015
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25749987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30308289
|full-text-url=https://sci-hub.do/10.1007/s11255-015-0917-0
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.10.004
}}
}}
==GAA==
* {{medline-title
* {{medline-title
|title=Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia.
|title=Inflammaging impairs peripheral nerve maintenance and regeneration.
|date=27.07.2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32586831
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30168637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260910
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Changes in Serum Guanidinoacetic Acid in Women.
|title=Stem Cell-Induced Pulp Regeneration Can Be Enhanced by Administration of [[CCL11]]-Neutralizing Antibody in the Ectopic Tooth Transplantation Model in the Aged Mice.
|date=30.12.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31647299
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29962294
|full-text-url=https://sci-hub.do/10.33549/physiolres.934189
|full-text-url=https://sci-hub.do/10.1089/rej.2018.2064
}}
}}
* {{medline-title
* {{medline-title
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|title=Inflammatory chemokine eotaxin-1 is correlated with age in heroin dependent patients under methadone maintenance therapy.
|date=2018
|date=01.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29222992
|full-text-url=https://sci-hub.do/10.1016/j.drugalcdep.2017.10.014
}}
==CCL5==


* {{medline-title
|title=[[CCL5]] secreted by senescent theca-interstitial cells inhibits preantral follicular development via granulosa cellular apoptosis.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31111482
|full-text-url=https://sci-hub.do/10.1002/jcp.28819
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Inflammatory markers and occurrence of falls: Bambuí Cohort Study of Aging.
|date=09.2017
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30942277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474745
}}
}}
* {{medline-title
* {{medline-title
|title=Age and gender-specific reference intervals for lysosomal enzymes in dried blood spot samples: A study in Indian population.
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|date=10.2017
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396248
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|full-text-url=https://sci-hub.do/10.1016/j.clinbiochem.2017.04.004
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of guanidinoacetic acid diet supplementation on semen quality and fertility of broiler breeder roosters.
|title=Burn wounds in the young versus the aged patient display differential immunological responses.
|date=02.2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28043349
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29895402
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2016.11.012
|full-text-url=https://sci-hub.do/10.1016/j.burns.2018.05.012
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of feeding guanidinoacetic acid and L-arginine on the fertility rate and sperm penetration in the perivitelline layer of aged broiler breeder hens.
|title=Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age.
|date=04.2016
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26216477
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891542
|full-text-url=https://sci-hub.do/10.1111/jpn.12372
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105902
}}
}}
* {{medline-title
* {{medline-title
|title=Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease.
|title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort.
|date=10.2015
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26001726
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2015.05.019
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006
}}
}}
==GCA==
* {{medline-title
* {{medline-title
|title=Familial aggregation of longevity in giant cell arteritis and polymyalgia rheumatica.
|title=Predictive value of multiple cytokines and chemokines for mortality in an admixed population: 15-year follow-up of the Bambui-Epigen (Brazil) cohort study of aging.
|date=12.2020
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32683496
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803133
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591435
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.002
}}
}}
==CD19==
* {{medline-title
* {{medline-title
|title=Interaction between Alcohol Consumption and Apolipoprotein E (ApoE) Genotype with Cognition in Middle-Aged Men.
|title=Sequential treatment with aT19 cells generates memory CAR-T cells and prolongs the lifespan of Raji-B-NDG mice.
|date=14.07.2020
|date=28.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32662384
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634527
|full-text-url=https://sci-hub.do/10.1017/S1355617720000570
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2019.10.022
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of young adult cognitive ability and additional education on later-life cognition.
|title=Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma
|date=05.02.2019
|date=18.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30670647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863019
}}
}}
* {{medline-title
* {{medline-title
|title=Altered effective connectivity anchored in the posterior cingulate cortex and the medial prefrontal cortex in cognitively intact elderly [[APOE]] ε4 carriers: a preliminary study.
|title=Effects of pepsin and pepstatin on reflux tonsil hypertrophy in vitro.
|date=02.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29549664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30408092
|full-text-url=https://sci-hub.do/10.1007/s11682-018-9857-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224077
}}
}}
* {{medline-title
* {{medline-title
|title=Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal Atrophy, and White Matter Hyperintensities.
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|date=05.2018
|date=05.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29314393
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932214
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
}}
}}
* {{medline-title
* {{medline-title
|title=Evaluation and clinical correlation of practical cut-offs for visual rating scales of atrophy: normal aging versus mild cognitive impairment and Alzheimer's disease.
|title=Vitamin D levels correlate with lymphocyte subsets in elderly patients with age-related diseases.
|date=09.2017
|date=16.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28397182
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769621
|full-text-url=https://sci-hub.do/10.1007/s13760-017-0777-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956012
}}
}}
* {{medline-title
* {{medline-title
|title=Neurodevelopmental origins of lifespan changes in brain and cognition.
|title=Normal variation of bone marrow B-cell precursors according to age - reference ranges for studies in myelodysplastic syndromes in Brazil.
|date=16.08.2016
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27432992
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29205788
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995982
|full-text-url=https://sci-hub.do/10.1002/cyto.b.21604
}}
}}
* {{medline-title
* {{medline-title
|title=Does degree of gyrification underlie the phenotypic and genetic associations between cortical surface area and cognitive ability?
|title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses.
|date=01.02.2015
|date=17.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25433211
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542
}}
}}
==GPI==
==CD63==


* {{medline-title
* {{medline-title
|title=Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain.
|title=Cellular senescence contributes to age-dependent changes in circulating extracellular vesicle cargo and function.
|date=10.07.2020
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32646997
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31960578
|full-text-url=https://sci-hub.do/10.1126/science.aaw2622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059145
}}
* {{medline-title
|title=Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging.
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220525
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116582
}}
}}
* {{medline-title
* {{medline-title
|title=Potential role of exercise-induced glucose-6-phosphate isomerase in skeletal muscle function.
|title=Adiponectin promotes muscle regeneration through binding to T-cadherin.
|date=30.06.2019
|date=09.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31337203
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30626897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327035
}}
}}
* {{medline-title
* {{medline-title
|title=Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria.
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529780
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223
}}
}}
* {{medline-title
* {{medline-title
|title=Can the health of a nation be correlated to its state of internal peace?
|title=The Aging Process Alters IL-1β and [[CD63]] Levels Differently in Extracellular Vesicles Obtained from the Plasma and Cerebrospinal Fluid.
|date=01-03.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27416918
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021215
|full-text-url=https://sci-hub.do/10.1080/13623699.2016.1207868
|full-text-url=https://sci-hub.do/10.1159/000488943
}}
}}
* {{medline-title
* {{medline-title
|title=Developmental role of the cell adhesion molecule Contactin-6 in the cerebral cortex and hippocampus.
|title=miRNA in Circulating Microvesicles as Biomarkers for Age-Related Cognitive Decline.
|date=03.07.2016
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26939565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29046635
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986711
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632661
}}
}}
* {{medline-title
* {{medline-title
|title=Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus).
|title=Circulating extracellular vesicles in the aging process: impact of aerobic exercise.
|date=11.2015
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26568298
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28819811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694066
|full-text-url=https://sci-hub.do/10.1007/s11010-017-3160-4
}}
}}
==CDKN1A==
* {{medline-title
* {{medline-title
|title=Urokinase receptor and resistance to targeted anticancer agents.
|title=Involvement of [[CDKN1A]] (p21) in cellular senescence in response to heat and irradiation stress during preimplantation development.
|date=2015
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26283964
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32253738
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193008
}}
}}
* {{medline-title
* {{medline-title
|title=The glycolytic enzyme, [[GPI]], is a functionally conserved modifier of dopaminergic neurodegeneration in Parkinson's models.
|title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells.
|date=01.07.2014
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24882066
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097176
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023
}}
}}
==GSTM1==
* {{medline-title
* {{medline-title
|title=The effects of everyday-life exposure to polycyclic aromatic hydrocarbons on biological age indicators.
|title=Histone demethylase [[KDM6B]] regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells.
|date=03.12.2020
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33272294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30825201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713168
|full-text-url=https://sci-hub.do/10.1002/jcp.28431
}}
}}
* {{medline-title
* {{medline-title
|title=Carrying the T Allele of the SNP rs574344, an eQTL of [[GSTM1]], Contributes to Longevity in the Han Chinese Population.
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|date=01.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30589570
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|full-text-url=https://sci-hub.do/10.1089/gtmb.2018.0178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Altered modulation of lamin A/C-[[HDAC2]] interaction and p21 expression during oxidative stress response in HGPS.
|date=12.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30109767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156291
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-dependent DNA hypermethylation and gene expression of [[GSTM1]] involved in T cell differentiation.
|title=Conditioned medium from stimulated macrophages inhibits growth but induces an inflammatory phenotype in breast cancer cells.
|date=25.07.2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28596482
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966967
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564710
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.06.126
}}
}}
* {{medline-title
* {{medline-title
|title=[Age features of cytogenetic effects of spring-summer encephalitis among residents of northern western Siberia in connection with polymorphism for genes of glutathione-S-transferase].
|title=DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice.
|date=2016
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28556645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877805
}}
==CLOCK==


* {{medline-title
|title=Investigating circadian clock gene expression in human tendon biopsies from acute exercise and immobilization studies.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923873
|full-text-url=https://sci-hub.do/10.1007/s00421-019-04129-2
}}
}}
* {{medline-title
* {{medline-title
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
|title=[[CLOCK]] gene polymorphisms and quality of aging in a cohort of nonagenarians - The MUGELLO Study.
|date=2016
|date=06.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30728411
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365537
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of [[APOE]] rs429358, rs7412 and [[GSTM1]]/[[GSTT1]] Polymorphism on Plasma and Erythrocyte Antioxidant Parameters and Cognition in Old Chinese Adults.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=24.09.2015
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26404360
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632411
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
* {{medline-title
* {{medline-title
|title=[Frequency of gene polymorphic variants (phase II) of biotransformation of [[GSTT1]] and [[GSTM1]] xenobiotics among long-livers (Precarpathian region)].
|title=Aging and chromatoid body assembly: Are these two physiological events linked?
|date=2013
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640692
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29958504
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108056
}}
}}
==HDAC2==
* {{medline-title
* {{medline-title
|title=EEF1A1 deacetylation enables transcriptional activation of remyelination.
|title=CIRCADIAN [[CLOCK]]-ASSOCIATED 1 Inhibits Leaf Senescence in [i]Arabidopsis[/i].
|date=09.07.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32647127
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29559987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347577
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845730
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16 .
|title=Circadian clocks: from stem cells to tissue homeostasis and regeneration.
|date=06.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29258993
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757216
}}
}}
* {{medline-title
* {{medline-title
|title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke.
|title=Female ClockΔ19/Δ19 mice are protected from the development of age-dependent cardiomyopathy.
|date=04.2019
|date=01.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28927226
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016
|full-text-url=https://sci-hub.do/10.1093/cvr/cvx185
}}
}}
==CR1==
* {{medline-title
* {{medline-title
|title=[[HDAC3]] Regulates the Transition to the Homeostatic Myelinating Schwann Cell State.
|title=Single Nucleotide Polymorphisms in Alzheimer's Disease Risk Genes Are Associated with Intrinsic Connectivity in Middle Age.
|date=04.12.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30517863
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32986668
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293966
|full-text-url=https://sci-hub.do/10.3233/JAD-200444
}}
}}
* {{medline-title
* {{medline-title
|title=Altered modulation of lamin A/C-[[HDAC2]] interaction and p21 expression during oxidative stress response in HGPS.
|title=The whale shark genome reveals how genomic and physiological properties scale with body size.
|date=10.2018
|date=25.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30109767
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32753383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456109
}}
}}
* {{medline-title
* {{medline-title
|title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.
|title=Mouse models of Alzheimer's disease cause rarefaction of pial collaterals and increased severity of ischemic stroke.
|date=09.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30519973
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475514
}}
}}
* {{medline-title
* {{medline-title
|title=Histone Deacetylase 2 Inhibition Attenuates Downregulation of Hippocampal Plasticity Gene Expression during Aging.
|title=Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia.
|date=03.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28364391
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429373
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0490-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303009
}}
}}
* {{medline-title
* {{medline-title
|title=Non-sirtuin histone deacetylases in the control of cardiac aging.
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=06.2015
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25791169
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459895
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
==IDH2==
* {{medline-title
 
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
* {{medline-title
* {{medline-title
|title=Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions.
|title=Associations between management practices and major reproductive parameters of Holstein-Friesian replacement heifers.
|date=10.09.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31503005
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175177
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756887
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2017.11.015
}}
}}
==CXCL10==
* {{medline-title
* {{medline-title
|title=Augmentation of cellular NAD  by [[NQO1]] enzymatic action improves age-related hearing impairment.
|title=Age-related decline of interferon-gamma responses in macrophage impairs satellite cell proliferation and regeneration.
|date=10.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31353811
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32725722
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718544
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567146
}}
}}
* {{medline-title
* {{medline-title
|title=Improving Treatment for Myelodysplastic Syndromes Patients.
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke.
|date=25.10.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362079
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008
|full-text-url=https://sci-hub.do/10.1007/s11864-018-0583-4
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of [[IDH2]] Accelerates Age-related Hearing Loss in Male Mice.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=22.03.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567975
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864918
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
* {{medline-title
* {{medline-title
|title=[[IDH2]]-deficient mice develop spinal deformities with aging.
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|date=17.07.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29527922
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|full-text-url=https://sci-hub.do/10.33549/physiolres.933711
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
}}
}}
* {{medline-title
* {{medline-title
|title=Idh2 deficiency accelerates renal dysfunction in aged mice.
|title=Aged Chinese-origin rhesus macaques infected with SIV develop marked viremia in absence of clinical disease, inflammation or cognitive impairment.
|date=04.11.2017
|date=01.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29391069
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796498
}}
}}
* {{medline-title
* {{medline-title
|title=[[IDH1]] Associated with Neuronal Apoptosis in Adult Rats Brain Following Intracerebral Hemorrhage.
|title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort.
|date=07.2017
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27568302
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791
|full-text-url=https://sci-hub.do/10.1007/s10571-016-0421-9
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic Aging Signatures Are Coherently Modified in Cancer.
|title=Dysregulation of C-X-C motif ligand 10 during aging and association with cognitive performance.
|date=06.2015
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26110659
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29223680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805841
}}
}}
==LPL==
==DBI==


* {{medline-title
* {{medline-title
|title=Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects.
|title=Quantifying cumulative anticholinergic and sedative drug load among US Medicare Beneficiaries.
|date=09.2020
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32684467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33000867
|full-text-url=https://sci-hub.do/10.3168/jds.2020-18174
|full-text-url=https://sci-hub.do/10.1002/pds.5144
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of common health disorders on the length of productive life and stayability in German Holstein cows.
|title=Drug Burden Index and Cognitive and Physical Function in Aged Care Residents: A Longitudinal Study.
|date=01.2020
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31677834
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736845
|full-text-url=https://sci-hub.do/10.3168/jds.2019-16985
|full-text-url=https://sci-hub.do/10.1016/j.jamda.2020.05.037
}}
}}
* {{medline-title
* {{medline-title
|title=GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling.
|title=Using the Drug Burden Index to identify older adults at highest risk for medication-related falls.
|date=07.2018
|date=12.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29694926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32532276
|full-text-url=https://sci-hub.do/10.1016/j.bone.2018.04.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291506
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle.
|title=Impact of STEADI-Rx: A Community Pharmacy-Based Fall Prevention Intervention.
|date=29.06.2017
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32315461
|full-text-url=https://sci-hub.do/10.4238/gmr16029091
|full-text-url=https://sci-hub.do/10.1111/jgs.16459
}}
}}
* {{medline-title
* {{medline-title
|title=Association of Metabolic Syndrome with Serum Adipokines in Community-Living Elderly Japanese Women: Independent Association with Plasminogen Activator-Inhibitor-1.
|title=Association of Drug Burden Index with grip strength, timed up and go and Barthel index activities of daily living in older adults with intellectual disabilities: an observational cross-sectional study.
|date=11.2015
|date=24.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26451494
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31234775
|full-text-url=https://sci-hub.do/10.1089/met.2015.0014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591943
}}
}}
* {{medline-title
* {{medline-title
|title=Moderate Exercise Mitigates the Detrimental Effects of Aging on Tendon Stem Cells.
|title=Impact of drug burden index on adverse health outcomes in Irish community-dwelling older people: a cohort study.
|date=2015
|date=29.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26086850
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31035946
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472753
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489229
}}
}}
* {{medline-title
* {{medline-title
|title=Association of adiponectin with serum preheparin lipoprotein lipase mass in women independent of fat mass and distribution, insulin resistance, and inflammation.
|title=Dietary Balance Index-07 and the Risk of Anemia in Middle Aged and Elderly People in Southwest China: A Cross Sectional Study.
|date=10.2014
|date=31.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24905278
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29385057
|full-text-url=https://sci-hub.do/10.1089/met.2014.0023
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852738
}}
}}
==FAS==
* {{medline-title
* {{medline-title
|title=[Clinical and genetic characteristics of long-livers in Moscow region].
|title=Five-year change in maximum tongue pressure and physical function in community-dwelling elderly adults.
|date=2013
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32952883
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486543
}}
}}
==LTA==
* {{medline-title
* {{medline-title
|title=Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice.
|title=Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity.
|date=02.2020
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814084
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32064756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059172
}}
}}
* {{medline-title
* {{medline-title
|title=The change of pain classes over time: a latent transition analysis.
|title=Application of GFR estimation equations in elderly patients with measured GFR below 60 mL/min/1.73 m .
|date=02.2020
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31680381
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31115878
|full-text-url=https://sci-hub.do/10.1002/ejp.1502
|full-text-url=https://sci-hub.do/10.1007/s40520-019-01218-2
}}
}}
* {{medline-title
* {{medline-title
|title=Leisure time activities as mediating variables in functional disability progression: An application of parallel latent growth curve modeling.
|title=Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes.
|date=2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30281590
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169861
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2019.01.005
}}
}}
* {{medline-title
* {{medline-title
|title=The Neighborhood Built Environment and Cognitive Function of Older Persons: Results from the Singapore Longitudinal Ageing Study.
|title=Genetic and Environmental Influences on Language Ability in Older Adults: Findings from the Older Australian Twins Study.
|date=2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28910813
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29619677
|full-text-url=https://sci-hub.do/10.1159/000480080
|full-text-url=https://sci-hub.do/10.1007/s10519-018-9897-z
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in depression among older adults in China: A latent transition analysis.
|title=Effects of aging on fat deposition and meat quality in Sheldrake duck.
|date=02.2017
|date=01.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866046
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29554357
|full-text-url=https://sci-hub.do/10.1016/j.jad.2016.11.004
|full-text-url=https://sci-hub.do/10.3382/ps/pey077
}}
}}
* {{medline-title
* {{medline-title
|title=Joint effect of gene-physical activity and the interactions among [[CRP]], [[TNF]]-α, and [[LTA]] polymorphisms on serum [[CRP]], [[TNF]]-α levels, and handgrip strength in community-dwelling elders in Taiwan - TCHS-E.
|title=Impact of sociodemographic variables on executive functions.
|date=04.2016
|date=01-03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27056089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29213495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005924
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619216
}}
}}
* {{medline-title
==MFI==
|title=In vitro anti-platelet potency of ticagrelor in blood samples from infants and children.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26210892
|full-text-url=https://sci-hub.do/10.1016/j.thromres.2015.07.013
}}
* {{medline-title
|title=Physical Activity, Mediterranean Diet and Biomarkers-Assessed Risk of Alzheimer's: A Multi-Modality Brain Imaging Study.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25599008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294269
}}
==MAG==


* {{medline-title
* {{medline-title
|title=Exploration of life satisfaction of Korean people with sensory impairments across the lifespan.
|title=The Influence of the Accelerated Aging Conditions on the Properties of Polyolefin Geogrids Used for Landfill Slope Reinforcement.
|date=10.2020
|date=20.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32327387
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32825284
|full-text-url=https://sci-hub.do/10.1016/j.dhjo.2020.100931
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564637
}}
}}
* {{medline-title
* {{medline-title
|title=Omega-3 Monoacylglyceride Effects on Longevity, Mitochondrial Metabolism and Oxidative Stress: Insights from [i]Drosophila melanogaster[/i].
|title=Changes in Physical Meat Traits, Protein Solubility, and the Microstructure of Different Beef Muscles during Post-Mortem Aging.
|date=16.11.2018
|date=19.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32575353
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266923
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353465
}}
}}
* {{medline-title
* {{medline-title
|title=Glial Sulfatides and Neuronal Complex Gangliosides Are Functionally Interdependent in Maintaining Myelinating Axon Integrity.
|title=Effect of a low-voltage electrical stimulation on yak meat tenderness during postmortem aging.
|date=02.01.2019
|date=01-12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30446529
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32583539
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325269
|full-text-url=https://sci-hub.do/10.1111/asj.13410
}}
}}
* {{medline-title
* {{medline-title
|title=Gray Matter Volume and Cognitive Performance During Normal Aging. A Voxel-Based Morphometry Study.
|title=Comparative effects of dry-aging and wet-aging on physicochemical properties and digestibility of Hanwoo beef.
|date=2018
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30123123
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31480178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085481
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054618
}}
}}
* {{medline-title
* {{medline-title
|title=Oxidative Stress Function in Women over 40 Years of Age, Considering Their Lifestyle.
|title=Sexual dimorphism in rat thymic involution: a correlation with thymic oxidative status and inflammation.
|date=2017
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28360887
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31119497
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352663
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09816-3
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in retinoic, docosahexaenoic and arachidonic acid modulation in nuclear lipid metabolism.
|title=Circulating soluble RAGE and cell surface RAGE on peripheral blood mononuclear cells in healthy children.
|date=15.08.2016
|date=27.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27355428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29723156
|full-text-url=https://sci-hub.do/10.1016/j.abb.2016.06.017
|full-text-url=https://sci-hub.do/10.1515/jpem-2017-0512
}}
}}
* {{medline-title
* {{medline-title
|title=Transcriptional and biochemical responses of monoacylglycerol acyltransferase-mediated oil synthesis and associated senescence-like responses in Nicotiana benthamiana.
|title=The frail fail: Increased mortality and post-operative complications in orthopaedic trauma patients.
|date=2014
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24904604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033622
|full-text-url=https://sci-hub.do/10.1016/j.injury.2017.08.026
}}
}}
==MMP13==
* {{medline-title
* {{medline-title
|title=Electromechanical delay of the knee extensor muscles: comparison among young, middle-age and older individuals.
|title=Aging aggravates intervertebral disc degeneration by regulating transcription factors toward chondrogenesis.
|date=07.2015
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24797398
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31909538
|full-text-url=https://sci-hub.do/10.1111/cpf.12157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018543
}}
}}
==MAP2==
* {{medline-title
* {{medline-title
|title=Protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent.
|title=[[EGR1]] promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling.
|date=11.2020
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32314365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201921
|full-text-url=https://sci-hub.do/10.1111/jnc.15029
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.06.010
}}
}}
* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Chondrocyte-Specific [[RUNX2]] Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice.
|date=04.07.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047611
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
|date=25.07.2018
|date=08.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31068441
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102613
}}
}}
* {{medline-title
* {{medline-title
|title=Systemic overexpression of [[SQSTM1]]/p62 accelerates disease onset in a [[SOD1]] -expressing ALS mouse model.
|title=Systemic clearance of p16  -positive senescent cells mitigates age-associated intervertebral disc degeneration.
|date=29.05.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843805
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30900385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516165
}}
}}
* {{medline-title
* {{medline-title
|title=Long-term treadmill exercise improves memory impairment through restoration of decreased synaptic adhesion molecule 1/2/3 induced by transient cerebral ischemia in the aged gerbil hippocampus.
|title=Design, cyclization, and optimization of [[MMP13]]-[[TIMP1]] interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis.
|date=03.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29341891
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352228
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.01.015
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.10.141
}}
}}
* {{medline-title
* {{medline-title
|title=Synaptic Compensation as a Probable Cause of Prolonged Mild Cognitive Impairment in Alzheimer's Disease: Implications from a Transgenic Mouse Model of the Disease.
|title=Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells.
|date=2017
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28222506
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344220
|full-text-url=https://sci-hub.do/10.3233/JAD-160845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755030
}}
}}
==MPO==
* {{medline-title
* {{medline-title
|title=Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.
|title=Impaired sleep quality is associated with concurrent elevations in inflammatory markers: are post-menopausal women at greater risk?
|date=21.05.2014
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24849348
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615113
}}
}}
* {{medline-title
* {{medline-title
|title=Removal of DELLA repression promotes leaf senescence in Arabidopsis.
|title=Local and systemic effects of aging on acute pancreatitis.
|date=04.2014
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24576761
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31204259
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2013.11.016
|full-text-url=https://sci-hub.do/10.1016/j.pan.2019.06.005
}}
}}
==MFI==
* {{medline-title
* {{medline-title
|title=The Influence of the Accelerated Aging Conditions on the Properties of Polyolefin Geogrids Used for Landfill Slope Reinforcement.
|title=Inflammatory signatures in older persons with physical frailty and sarcopenia: The frailty "cytokinome" at its core.
|date=20.08.2020
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32825284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31054959
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564637
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.04.019
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in Physical Meat Traits, Protein Solubility, and the Microstructure of Different Beef Muscles during Post-Mortem Aging.
|title=Astaxanthin-Rich [i]Haematococcus pluvialis[/i] Algal Hepatic Modulation in D-Galactose-Induced Aging in Rats: Role of Nrf2.
|date=19.06.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32575353
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30276150
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156486
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of a low-voltage electrical stimulation on yak meat tenderness during postmortem aging.
|title=Effect of β-D-Mannuronic Acid (M2000) on Oxidative Stress Enzymes' Gene Using Healthy Donor Peripheral Blood Mononuclear Cells for Evaluating the Anti-Aging Property.
|date=01-12.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32583539
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29766814
|full-text-url=https://sci-hub.do/10.1111/asj.13410
|full-text-url=https://sci-hub.do/10.2174/1570163815666180515122834
}}
}}
* {{medline-title
* {{medline-title
|title=Comparative effects of dry-aging and wet-aging on physicochemical properties and digestibility of Hanwoo beef.
|title=Chlorinative stress in age-related diseases: a literature review.
|date=03.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31480178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054618
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686828
}}
}}
* {{medline-title
* {{medline-title
|title=Sexual dimorphism in rat thymic involution: a correlation with thymic oxidative status and inflammation.
|title=Hippocampal-dependent memory deficit induced by perinatal exposure to polutted eels in middle-aged offspring mice: Sex differential effects.
|date=08.2019
|date=05.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31119497
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847518
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09816-3
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2017.08.019
}}
}}
==NOX4==
* {{medline-title
* {{medline-title
|title=Circulating soluble RAGE and cell surface RAGE on peripheral blood mononuclear cells in healthy children.
|title=Sestrin2 Attenuates Cellular Senescence by Inhibiting NADPH Oxidase 4 Expression.
|date=27.06.2018
|date=24.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29723156
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33227845
|full-text-url=https://sci-hub.do/10.1515/jpem-2017-0512
|full-text-url=https://sci-hub.do/10.4235/agmr.20.0051
}}
}}
* {{medline-title
* {{medline-title
|title=The frail fail: Increased mortality and post-operative complications in orthopaedic trauma patients.
|title=NADPH Oxidases and Aging Models of Lung Fibrosis.
|date=11.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888718
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31172491
|full-text-url=https://sci-hub.do/10.1016/j.injury.2017.08.026
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-9424-3_29
}}
}}
* {{medline-title
* {{medline-title
|title=Meat quality attributes of Agile Wallabies.
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|date=11.2017
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28697421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|full-text-url=https://sci-hub.do/10.1016/j.meatsci.2017.06.016
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
}}
}}
==MIA==
* {{medline-title
* {{medline-title
|title=Age, cohort, and period effects on metamemory beliefs.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=12.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31804113
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901096
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
* {{medline-title
* {{medline-title
|title=Memory Age-based Stereotype Threat: Role of Locus of Control and Anxiety.
|title=Redox Imbalance in Idiopathic Pulmonary Fibrosis: A Role for Oxidant Cross-Talk Between NADPH Oxidase Enzymes and Mitochondria.
|date=01-02.2020
|date=10.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31752597
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30793932
|full-text-url=https://sci-hub.do/10.1080/0361073X.2019.1693009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767863
}}
}}
* {{medline-title
* {{medline-title
|title=Role of melanoma inhibitory activity in melanocyte senescence.
|title=NADPH oxidase 4 mediates ROS production in radiation-induced senescent cells and promotes migration of inflammatory cells.
|date=11.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31172672
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228832
|full-text-url=https://sci-hub.do/10.1111/pcmr.12801
|full-text-url=https://sci-hub.do/10.1080/10715762.2017.1416112
}}
}}
* {{medline-title
* {{medline-title
|title=Refining the metamemory in adulthood questionnaire: a 20-item version of change and capacity designed for research and clinical settings.
|title=Alternative Splicing of [[NOX4]] in the Failing Human Heart.
|date=07.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30957531
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29204124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698687
}}
}}
==NPY==
* {{medline-title
* {{medline-title
|title=Maternal Immune Activation Alters Adult Behavior, Gut Microbiome and Juvenile Brain Oscillations in Ferrets.
|title=Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells.
|date=09-10.2018
|date=22.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30406186
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012215
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220580
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243588
}}
}}
* {{medline-title
* {{medline-title
|title=Differential proteomic and oxidative profiles unveil dysfunctional protein import to adipocyte mitochondria in obesity-associated aging and diabetes.
|title=Effects of rikkunshito supplementation on resistance to oxidative stress and lifespan in mice.
|date=04.2017
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28064117
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31855319
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220168
|full-text-url=https://sci-hub.do/10.1111/ggi.13848
}}
}}
* {{medline-title
* {{medline-title
|title=Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice.
|title=Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner.
|date=06.2015
|date=21.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25971876
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30899013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428838
}}
}}
* {{medline-title
* {{medline-title
|title=Factors associated with hypertension prevalence, awareness, treatment and control among participants in the International Mobility in Aging Study (I[[MIA]]S).
|title=β-Alanine supplementation reduces anxiety and increases neurotrophin expression in both young and older rats.
|date=02.2016
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25833704
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30803507
|full-text-url=https://sci-hub.do/10.1038/jhh.2015.30
|full-text-url=https://sci-hub.do/10.1016/j.nutres.2018.11.001
}}
}}
==MITF==
* {{medline-title
* {{medline-title
|title=Thymocid , a Standardized Black Cumin ([i]Nigella sativa[/i]) Seed Extract, Modulates Collagen Cross-Linking, Collagenase and Elastase Activities, and Melanogenesis in Murine B16F10 Melanoma Cells.
|title=Age-related central regulation of orexin and [[NPY]] in the short-lived African killifish Nothobranchius furzeri.
|date=19.07.2020
|date=15.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32707654
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400895
|full-text-url=https://sci-hub.do/10.1002/cne.24638
}}
* {{medline-title
|title=Chronic treatment with tributyltin induces sexually dimorphic alterations in the hypothalamic [[POMC]] system of adult mice.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30078105
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2896-9
}}
* {{medline-title
|title=Expression of CGRP neurotransmitter and vascular genesis marker mRNA is age-dependent in superior cervical ganglia of senescence-accelerated prone mice.
|date=18.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154859
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.11.034
}}
}}
==OPA1==
* {{medline-title
* {{medline-title
|title=HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth.
|title=[i]Sirt3[/i] Deficiency Shortens Life Span and Impairs Cardiac Mitochondrial Function Rescued by [i]Opa1[/i] Gene Transfer.
|date=21.05.2020
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32455577
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31269804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281285
|full-text-url=https://sci-hub.do/10.1089/ars.2018.7703
}}
}}
* {{medline-title
* {{medline-title
|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells.
|title=Novel role of the [[SIRT4]]-[[OPA1]] axis in mitochondrial quality control.
|date=01.2020
|date=23.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225445
|full-text-url=https://sci-hub.do/10.1111/pcmr.12811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551841
}}
}}
* {{medline-title
* {{medline-title
|title=H O  promotes the aging process of melanogenesis through modulation of [[MITF]] and Nrf2.
|title=Inhibition of the Fission Machinery Mitigates [[OPA1]] Impairment in Adult Skeletal Muscles.
|date=04.2019
|date=15.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805890
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208084
|full-text-url=https://sci-hub.do/10.1007/s11033-019-04708-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627087
}}
}}
* {{medline-title
* {{medline-title
|title=Deregulated [[MITF]] sumoylation: A route to melanoma.
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.
|date=2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28868345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
}}
}}
* {{medline-title
* {{medline-title
|title=Phosphorylation of [[MITF]] by AKT affects its downstream targets and causes [[TP53]]-dependent cell senescence.
|title=[[SIRT4]] interacts with [[OPA1]] and regulates mitochondrial quality control and mitophagy.
|date=11.2016
|date=29.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27702651
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081403
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2016.09.029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680561
}}
}}
* {{medline-title
* {{medline-title
|title=Parthenolide induces [[MITF]]-M downregulation and senescence in patient-derived [[MITF]]-M(high) melanoma cell populations.
|title=Optic atrophy 1 mediates coenzyme Q-responsive regulation of respiratory complex IV activity in brain mitochondria.
|date=23.02.2016
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26824319
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28890359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891023
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.002
}}
}}
* {{medline-title
* {{medline-title
|title=Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma.
|title=Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats.
|date=06.2014
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25030625
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198745
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.017
}}
}}
==MMP3==
==RET==


* {{medline-title
* {{medline-title
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|title=Effects of resistance exercise training on redox homeostasis in older adults. A systematic review and meta-analysis.
|date=14.11.2017
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32615210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111012
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of a pyridine derivative inducing senescence in ovarian cancer cell lines via P21 activation.
|title=Effects of an 8-week resistance training intervention on plantar flexor muscle quality and functional capacity in older women: A randomised controlled trial.
|date=05.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143360
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32562747
|full-text-url=https://sci-hub.do/10.1111/1440-1681.12891
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.111003
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells.
|title=Resistance exercise training promotes fiber type-specific myonuclear adaptations in older adults.
|date=01.09.2017
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28329136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32134710
|full-text-url=https://sci-hub.do/10.1093/gerona/glw336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191507
}}
}}
* {{medline-title
* {{medline-title
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|title=Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults.
|date=10.2016
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31518665
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904952
}}
}}
* {{medline-title
* {{medline-title
|title=Differential Matrix Metalloprotease (MMP) Expression Profiles Found in Aged Gingiva.
|title=Resistance Exercise Training as a Primary Countermeasure to Age-Related Chronic Disease.
|date=2016
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31244666
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563593
}}
}}
* {{medline-title
* {{medline-title
|title=Role of [[SHOX2]] in the development of intervertebral disc degeneration.
|title=Physical, Chemical, Microstructural and Rheological Properties of Reactive Terpolymer-Modified Bitumen.
|date=05.2017
|date=20.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26697824
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30897695
|full-text-url=https://sci-hub.do/10.1002/jor.23140
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471383
}}
}}
* {{medline-title
* {{medline-title
|title=Biological Effects Induced by Specific Advanced Glycation End Products in the Reconstructed Skin Model of Aging.
|title=Citrulline counteracts overweight- and aging-related effects on adiponectin and leptin gene expression in rat white adipose tissue.
|date=2015
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26309782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632824
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497626
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889428
}}
* {{medline-title
|title=Anti-photoaging potential of Botulinum Toxin Type A in UVB-induced premature senescence of human dermal fibroblasts in vitro through decreasing senescence-related proteins.
|date=05.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24727404
|full-text-url=https://sci-hub.do/10.1016/j.jphotobiol.2014.03.009
}}
}}
==MOS==
==SPARC==


* {{medline-title
* {{medline-title
|title=Effect of mannan oligosaccharides on the microbiota and productivity parameters of Litopenaeus vannamei shrimp under intensive cultivation in Ecuador.
|title=[[SPARC]] Metrics Provide Mobility Smoothness Assessment in Oldest-Old With and Without a History of Falls: A Case Control Study.
|date=17.02.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32066764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32587523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298141
}}
}}
* {{medline-title
* {{medline-title
|title=Predictors of health-related quality of life among older adults living with HIV in Thailand: results from the baseline and follow-up surveys.
|title=Reduced fibrillar collagen accumulation in skeletal muscle of secreted protein acidic and rich in cysteine ([[SPARC]])-null mice.
|date=23.12.2019
|date=29.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31870166
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31582603
|full-text-url=https://sci-hub.do/10.1080/09540121.2019.1707472
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895640
}}
}}
* {{medline-title
* {{medline-title
|title=Comparison of health-related quality of life between the Han and Yi ethnicity elderly in the Yi autonomous areas of Yunnan Province.
|title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment.
|date=25.11.2019
|date=18.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31766992
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878633
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664
}}
}}
* {{medline-title
* {{medline-title
|title=Mannan oligosaccharide increases the growth performance, immunity and resistance capability against Vibro Parahemolyticus in juvenile abalone Haliotis discus hannai Ino.
|title=Lifelong aerobic exercise protects against inflammaging and cancer.
|date=11.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31561025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30682077
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2019.09.058
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347267
}}
}}
* {{medline-title
* {{medline-title
|title=A global human health risk assessment for octamethylcyclotetrasiloxane (D ).
|title=[[SPARC]] is required for the maintenance of glucose homeostasis and insulin secretion in mice.
|date=20.10.2017
|date=31.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28522410
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30626728
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2017.05.019
|full-text-url=https://sci-hub.do/10.1042/CS20180714
}}
}}
* {{medline-title
* {{medline-title
|title=Comprehensive Assessment of Compliance with Antimuscarinic Drug Treatment in the Case of Urge Urinary Incontinence of Older Patients.
|title=Aging may negatively impact movement smoothness during stair negotiation.
|date=2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889999
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843055
|full-text-url=https://sci-hub.do/10.2174/1874609808666161124143150
|full-text-url=https://sci-hub.do/10.1016/j.humov.2018.05.008
}}
}}
* {{medline-title
* {{medline-title
|title=Sleep Disordered Breathing and White Matter Hyperintensities in Community-Dwelling Elders.
|title=The impact of [[SPARC]] on age-related cardiac dysfunction and fibrosis in Drosophila.
|date=01.04.2016
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27071695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29032244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094046
}}
* {{medline-title
|title=Effects of narrow base gait on mediolateral balance control in young and older adults.
|date=03.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27018156
|full-text-url=https://sci-hub.do/10.1016/j.jbiomech.2016.03.011
}}
}}
==NNT==
==TOMM40==


* {{medline-title
* {{medline-title
|title=Yoga, Health-Related Quality of Life and Mental Well-Being: A Re-analysis of a Meta-analysis Using the Quality Effects Model.
|title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.
|date=16.09.2020
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706571
|full-text-url=https://sci-hub.do/10.1093/gerona/glz284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608707
}}
}}
* {{medline-title
* {{medline-title
|title=Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database.
|title=Independent associations of [[TOMM40]] and [[APOE]] variants with body mass index.
|date=02.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31647578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30462377
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351823
}}
}}
* {{medline-title
* {{medline-title
|title=Years of Life Lost for Older Patients After Colorectal Cancer Diagnosis.
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|date=08.2019
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30863872
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|full-text-url=https://sci-hub.do/10.1007/s00268-019-04978-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet.
|title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30281804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048
|full-text-url=https://sci-hub.do/10.1111/jnc.14602
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481
}}
}}
* {{medline-title
* {{medline-title
|title=Upregulation of mitochondrial NAD  levels impairs the clonogenicity of SSEA1  glioblastoma tumor-initiating cells.
|title=Apolipoprotein E region molecular signatures of Alzheimer's disease.
|date=09.06.2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28604662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797398
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052488
}}
}}
* {{medline-title
* {{medline-title
|title=The Health Gain Obtainable from Pancreatic Resection for Adenocarcinoma in the Elderly.
|title=Genetic Variation in [[FOXO3]] is Associated with Self-Rated Health in a Population-Based Sample of Older Individuals.
|date=04.2017
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27826771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415201
|full-text-url=https://sci-hub.do/10.1007/s00268-016-3793-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175024
}}
}}
* {{medline-title
* {{medline-title
|title=Restoration of Mitochondrial NAD  Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells.
|title=Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort.
|date=12.2016
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27428041
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28800603
|full-text-url=https://sci-hub.do/10.1002/stem.2460
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553750
}}
* {{medline-title
|title=Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons.
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24655393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116450
}}
}}
==NPS==
==TST==


* {{medline-title
* {{medline-title
|title=Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging.
|title=H S Donors Reverse Age-Related Gastric Malfunction Impaired Due to Fructose-Induced Injury [i]via[/i] CBS, CSE, and [[TST]] Expression.
|date=28.03.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923322
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32848752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438979
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396573
}}
}}
* {{medline-title
* {{medline-title
|title=Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults.
|title=Adaptations in mechanical muscle function, muscle morphology, and aerobic power to high-intensity endurance training combined with either traditional or power strength training in older adults: a randomized clinical trial.
|date=08.2019
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30902566
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32239311
|full-text-url=https://sci-hub.do/10.1016/j.jagp.2019.01.215
|full-text-url=https://sci-hub.do/10.1007/s00421-020-04355-z
}}
}}
* {{medline-title
* {{medline-title
|title=The course of neuropsychiatric symptoms in patients with dementia in primary care.
|title=Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging.
|date=31.07.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30517631
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31602410
|full-text-url=https://sci-hub.do/10.1093/fampra/cmy117
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778117
}}
}}
* {{medline-title
* {{medline-title
|title=Serum calcium levels and neuropsychological performance in depression and matched healthy controls: Reversal of correlation a marker of the aging cognitive clock?
|title=Objective Sleep Duration in Older Adults: Results From The Irish Longitudinal Study on Ageing.
|date=05.2018
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587243
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31579942
|full-text-url=https://sci-hub.do/10.1016/j.psyneuen.2018.03.012
|full-text-url=https://sci-hub.do/10.1111/jgs.16177
}}
}}
* {{medline-title
* {{medline-title
|title=Persistent use of psychotropic drugs in nursing home residents in Norway.
|title=Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis.
|date=13.02.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28193181
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31312133
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307887
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614445
}}
}}
* {{medline-title
* {{medline-title
|title=FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging.
|title=Validity Evaluation of the Fitbit Charge2 and the Garmin vivosmart HR+ in Free-Living Environments in an Older Adult Cohort.
|date=14.07.2016
|date=19.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27447426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219048
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981903
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607774
}}
}}
* {{medline-title
* {{medline-title
|title=Cardiorenal fibrosis and dysfunction in aging: Imbalance in mediators and regulators of collagen.
|title=Paradoxical effect of testosterone supplementation therapy on cardiac ischemia/reperfusion injury in aged rats.
|date=02.2016
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26774586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754975
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.012
}}
}}
==UCP2==
* {{medline-title
* {{medline-title
|title=Personalized technology to support older adults with and without cognitive impairment living at home.
|title=Potential Role of Leptin in Cardiac Steatosis Induced by Highly Saturated Fat Intake during Adolescence.
|date=02.2015
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25614507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298470
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819239
|full-text-url=https://sci-hub.do/10.1002/mnfr.201900110
}}
}}
==POLG==
* {{medline-title
* {{medline-title
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|title=Effect of Initial Aging and High-Fat/High-Fructose Diet on Mitochondrial Bioenergetics and Oxidative Status in Rat Brain.
|date=08.07.2019
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089964
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
|full-text-url=https://sci-hub.do/10.1007/s12035-019-1617-z
}}
}}
* {{medline-title
* {{medline-title
|title=Parkin does not prevent accelerated cardiac aging in mitochondrial DNA mutator mice.
|title=Decreased uncoupling protein 2 expression in aging retinal pigment epithelial cells.
|date=16.04.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30990467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30918803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423381
}}
}}
* {{medline-title
* {{medline-title
|title=The effects of AICAR and rapamycin on mitochondrial function in immortalized mitochondrial DNA mutator murine embryonic fibroblasts.
|title=The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature.
|date=16.11.2018
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30177551
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30676214
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262855
|full-text-url=https://sci-hub.do/10.1123/japa.2018-0155
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of exercise on oocyte quality in the [[POLG]] mitochondrial DNA mutator mouse.
|title=G-1 exhibit antidepressant effect, increase of hippocampal ERs expression and improve hippocampal redox status in aged female rats.
|date=08.2018
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875308
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30041006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074767
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2018.07.017
}}
}}
* {{medline-title
* {{medline-title
|title=The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways.
|title=Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts.
|date=08.2017
|date=21.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28499253
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29931650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060207
}}
}}
* {{medline-title
* {{medline-title
|title=Metabolomic analysis of exercise effects in the [[POLG]] mitochondrial DNA mutator mouse brain.
|title=Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/[[PGC]]-1α pathway.
|date=11.2015
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26294258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325933
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820139
}}
}}
==VDR==
* {{medline-title
* {{medline-title
|title=Mitochondria DNA mutations cause sex-dependent development of hypertension and alterations in cardiovascular function.
|title=25-Hydroxyvitamin D  positively regulates periodontal inflammaging via SOCS3/STAT signaling in diabetic mice.
|date=05.02.2015
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25582357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31917967
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306604
|full-text-url=https://sci-hub.do/10.1016/j.steroids.2019.108570
}}
}}
* {{medline-title
* {{medline-title
|title=Somatic mitochondrial DNA mutations do not increase neuronal  vulnerability to MPTP in young [[POLG]] mutator mice.
|title=1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel [[VDR]]-Ezh2-p16 signal axis.
|date=11-12.2014
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25450660
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31880094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293310
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996957
}}
}}
==RAD51==
* {{medline-title
* {{medline-title
|title=Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium.
|title=Active vitamin D impedes the progression of non-alcoholic fatty liver disease by inhibiting cell senescence in a rat model.
|date=09.07.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31291576
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31810868
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.06.043
|full-text-url=https://sci-hub.do/10.1016/j.clinre.2019.10.007
}}
}}
* {{medline-title
* {{medline-title
|title=Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae.
|title=Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H O -induced apoptosis in rat intervertebral disc cells.
|date=01.08.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075257
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30905826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563841
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.013
}}
}}
* {{medline-title
* {{medline-title
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|title=Vitamin D Receptor in Muscle Atrophy of Elderly Patients: A Key Element of Osteoporosis-Sarcopenia Connection.
|date=2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284754
}}
}}
* {{medline-title
* {{medline-title
|title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment.
|title=Reduced vitamin D receptor ([[VDR]]) expression and plasma vitamin D levels are associated with aging-related prostate lesions.
|date=2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29508414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527
|full-text-url=https://sci-hub.do/10.1002/pros.23498
}}
}}
* {{medline-title
* {{medline-title
|title=Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence.
|title=[[VDR]] Activation Reduces Proteinuria and High-Glucose-Induced Injury of Kidneys and Podocytes by Regulating Wnt Signaling Pathway.
|date=11.10.2016
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27626497
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28848172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341871
|full-text-url=https://sci-hub.do/10.1159/000480315
}}
}}
==ADAM10==
* {{medline-title
* {{medline-title
|title=BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries.
|title=NKG2D Ligand Shedding in Response to Stress: Role of [[ADAM10]].
|date=03.04.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552356
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32269567
|full-text-url=https://sci-hub.do/10.1080/10495398.2016.1210613
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109295
}}
}}
* {{medline-title
* {{medline-title
|title=[[SQSTM1]]/p62 mediates crosstalk between autophagy and the UPS in DNA repair.
|title=Chronic Mild Stress Modified Epigenetic Mechanisms Leading to Accelerated Senescence and Impaired Cognitive Performance in Mice.
|date=02.10.2016
|date=10.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391408
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32050516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037343
}}
}}
* {{medline-title
* {{medline-title
|title=[[RECQL5]] has unique strand annealing properties relative to the other human RecQ helicase proteins.
|title=Removal of p75 Neurotrophin Receptor Expression from Cholinergic Basal Forebrain Neurons Reduces Amyloid-β Plaque Deposition and Cognitive Impairment in Aged APP/PS1 Mice.
|date=01.2016
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26717024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30374941
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903426
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1404-2
}}
}}
==SQSTM1==
* {{medline-title
* {{medline-title
|title=The selective autophagy receptor [[SQSTM1]]/p62 improves lifespan and proteostasis in an evolutionarily conserved manner.
|title=11β-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model.
|date=04.2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041473
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29611102
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138197
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1026-8
}}
* {{medline-title
|title=Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells.
|date=15.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29348391
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811245
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT2]] functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.
|title=microRNA 221 Targets [[ADAM10]] mRNA and is Downregulated in Alzheimer's Disease.
|date=01.09.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31295472
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29036829
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116639
|full-text-url=https://sci-hub.do/10.3233/JAD-170592
}}
}}
==AIP==
* {{medline-title
* {{medline-title
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|title=[Aryl hydrocarbon receptor interacting protein ([[AIP]]) in human dermis during aging.]
|date=07.12.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33280328
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
 
}}
}}
* {{medline-title
* {{medline-title
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|title=Sex-Specific Association between Serum Vitamin D Status and Lipid Profiles: A Cross-Sectional Study of a Middle-Aged and Elderly Chinese Population.
|date=04.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32350171
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
|full-text-url=https://sci-hub.do/10.3177/jnsv.66.105
}}
}}
* {{medline-title
* {{medline-title
|title=Systemic overexpression of [[SQSTM1]]/p62 accelerates disease onset in a [[SOD1]] -expressing ALS mouse model.
|title=The oblique effect: The relationship between profiles of visuospatial preference, cognition, and brain connectomics in older adults.
|date=29.05.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843805
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31654648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887099
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=A logic of choice: Problematizing the documentary reality of Canadian aging in place policies.
|date=09.2017
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30832929
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://sci-hub.do/10.1016/j.jaging.2019.01.002
}}
}}
* {{medline-title
* {{medline-title
|title=[[SQSTM1]]/p62 mediates crosstalk between autophagy and the UPS in DNA repair.
|title=Enhanced basal late sodium current appears to underlie the age-related prolongation of action potential duration in guinea pig ventricular myocytes.
|date=02.10.2016
|date=14.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391408
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29357519
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391493
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00916.2017
}}
}}
* {{medline-title
* {{medline-title
|title=Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis.
|title=Building IoT Services for Aging in Place Using Standard-Based IoT Platforms and Heterogeneous IoT Products.
|date=02.11.2015
|date=11.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29019964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824610
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677444
}}
}}
==SUV39H1==
==AKT1==


* {{medline-title
* {{medline-title
|title=Increase in hippocampal histone H3K9me3 is negatively correlated with memory in old male mice.
|title=MicroRNA-495 enhances chondrocyte apoptosis, senescence and promotes the progression of osteoarthritis by targeting [[AKT1]].
|date=04.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31760560
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31105831
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09850-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511756
}}
}}
* {{medline-title
* {{medline-title
|title=Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=27.09.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952292
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
* {{medline-title
* {{medline-title
|title=The Ubiquitin-like with PHD and Ring Finger Domains 1 ([[UHRF1]])/DNA Methyltransferase 1 ([[DNMT1]]) Axis Is a Primary Regulator of Cell Senescence.
|title=The biological age linked to oxidative stress modifies breast cancer aggressiveness.
|date=03.03.2017
|date=20.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28100769
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29550329
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339756
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.03.012
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Associated Decrease of the Histone Methyltransferase [[SUV39H1]] in HSC Perturbs Heterochromatin and B Lymphoid Differentiation.
|title=Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement.
|date=14.06.2016
|date=05.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27304919
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911502
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788639
}}
}}
* {{medline-title
* {{medline-title
|title=H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases [[BDNF]] Levels in the Aged Hippocampus.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=23.03.2016
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27013689
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
* {{medline-title
* {{medline-title
|title=Stem Cell Depletion by Global Disorganization of the H3K9me3 Epigenetic Marker in Aging.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=08.2015
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26160351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://sci-hub.do/10.1089/rej.2015.1742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==ALDH2==
* {{medline-title
* {{medline-title
|title=Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging.
|title=Aldehyde Dehydrogenase 2 ([[ALDH2]]) and Aging: Is There a Sensible Link?
|date=05.06.2015
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25931448
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31368109
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494668
|full-text-url=https://sci-hub.do/10.1007/978-981-13-6260-6_15
}}
}}
* {{medline-title
* {{medline-title
|title=[[SUV39H1]] downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation.
|title=Appropriate dose of ethanol exerts anti-senescence and anti-atherosclerosis protective effects by activating [[ALDH2]].
|date=2014
|date=30.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25484892
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885430
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240170
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.03.037
}}
}}
==TRPM2==
* {{medline-title
* {{medline-title
|title=Paraquat as an Environmental Risk Factor in Parkinson's Disease Accelerates Age-Related Degeneration Via Rapid Influx of Extracellular Zn  into Nigral Dopaminergic Neurons.
|title=Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue.
|date=11.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31119555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472277
|full-text-url=https://sci-hub.do/10.1007/s12035-019-01642-5
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.013
}}
}}
* {{medline-title
* {{medline-title
|title=Pathophysiological Role of [[TRPM2]] in Age-Related Cognitive Impairment in Mice.
|title=Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde.
|date=01.06.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30999030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466069
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2019.04.012
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2018.11.007
}}
}}
* {{medline-title
* {{medline-title
|title=The [[TRPM2]] channel nexus from oxidative damage to Alzheimer's pathologies: An emerging novel intervention target for age-related dementia.
|title=Aldehyde dehydrogenase 2 deficiency promotes atherosclerotic plaque instability through accelerating mitochondrial ROS-mediated vascular smooth muscle cell senescence.
|date=11.2018
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30009973
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30315930
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.002
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.09.033
}}
}}
* {{medline-title
* {{medline-title
|title=[[TRPM2]] in the Brain: Role in Health and Disease.
|title=[[ALDH2]] mediates the dose-response protection of chronic ethanol against endothelial senescence through [[SIRT1]]/p53 pathway.
|date=22.07.2018
|date=12.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037128
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217444
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070997
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.081
}}
}}
==ARNT==
* {{medline-title
* {{medline-title
|title=mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development.
|title=Loss of [[ARNT]] in skeletal muscle limits muscle regeneration in aging.
|date=10.2018
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29842890
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33064329
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.05.008
|full-text-url=https://sci-hub.do/10.1096/fj.202000761RR
}}
}}
* {{medline-title
* {{medline-title
|title=Prolactin protects retinal pigment epithelium by inhibiting sirtuin 2-dependent cell death.
|title=[Arylhydrocarbon receptor nuclear translocator ([[ARNT]]) in human skin during aging.]
|date=05.2016
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27322457
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909382
 
}}
}}
* {{medline-title
* {{medline-title
|title=Extended therapeutic window of a novel peptide inhibitor of [[TRPM2]] channels following focal cerebral ischemia.
|title=The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1.
|date=09.2016
|date=03.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27317297
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240152
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135990
}}
}}
* {{medline-title
* {{medline-title
|title=The Protective Role of Selenium on Scopolamine-Induced Memory Impairment, Oxidative Stress, and Apoptosis in Aged Rats: The Involvement of [[TRPM2]] and [[TRPV1]] Channels.
|title=Deficiency of Bmal1 disrupts the diurnal rhythm of haemostasis.
|date=05.2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27021021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30610898
|full-text-url=https://sci-hub.do/10.1007/s12035-016-9835-0
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.12.017
}}
}}
==TRPV4==
* {{medline-title
* {{medline-title
|title=[[TRPV4]] receptor as a functional sensory molecule in bladder urothelium: Stretch-independent, tissue-specific actions and pathological implications.
|title=Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling.
|date=01.2020
|date=02.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31914645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973053
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222112
}}
}}
* {{medline-title
* {{medline-title
|title=Exercise restores impaired endothelium-derived hyperpolarizing factor-mediated vasodilation in aged rat aortic arteries via the [[TRPV4]]-K 2.3 signaling complex.
|title=Aging and chromatoid body assembly: Are these two physiological events linked?
|date=2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31564840
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29958504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731547
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108056
}}
}}
==BRCA2==
* {{medline-title
* {{medline-title
|title=Autonomic dysregulation at multiple sites is implicated in age-associated underactive bladder in female mice.
|title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.
|date=06.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30932250
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397
|full-text-url=https://sci-hub.do/10.1002/nau.23990
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141
}}
}}
* {{medline-title
* {{medline-title
|title=Reduced bladder responses to capsaicin and GSK-1016790A in retired-breeder female rats with diminished volume sensitivity.
|title=Klotho gene polymorphisms are associated with healthy aging and longevity: Evidence from a meta-analysis.
|date=01.11.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019934
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30633899
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00198.2018
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.12.003
}}
}}
* {{medline-title
* {{medline-title
|title=Cartilage-Specific Knockout of the Mechanosensory Ion Channel [[TRPV4]] Decreases Age-Related Osteoarthritis.
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.
|date=08.07.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27388701
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937413
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081
}}
}}
* {{medline-title
* {{medline-title
|title=Increasing [[TRPV4]] expression restores flow-induced dilation impaired in mesenteric arteries with aging.
|title=Faulty [[BRCA1]], [[BRCA2]] genes: how poor is the prognosis?
|date=07.03.2016
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26947561
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29017890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780030
|full-text-url=https://sci-hub.do/10.1016/j.annepidem.2017.09.005
}}
}}
* {{medline-title
* {{medline-title
|title=Berberine via suppression of transient receptor potential vanilloid 4 channel improves vascular stiffness in mice.
|title=Ovarian Aging in Women With BRCA Germline Mutations.
|date=11.2015
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26177349
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28938488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627566
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630253
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in the distribution of transient receptor potential vanilloid 4 channel ([[TRPV4]]) in the central nervous system of rats.
|title=The expected benefit of preventive mastectomy on breast cancer incidence and mortality in BRCA mutation carriers, by age at mastectomy.
|date=10.2014
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24917364
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28914396
|full-text-url=https://sci-hub.do/10.1007/s10735-014-9578-z
|full-text-url=https://sci-hub.do/10.1007/s10549-017-4476-1
}}
}}
==VWF==
==C9==


* {{medline-title
* {{medline-title
|title=Von Willebrand disease in the elderly: clinical perspectives.
|title=[[C9]]orf72 in myeloid cells suppresses STING-induced inflammation.
|date=2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30214173
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32814898
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124462
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484469
}}
}}
* {{medline-title
* {{medline-title
|title=Comorbidities associated with higher von Willebrand factor ([[VWF]]) levels may explain the age-related increase of [[VWF]] in von Willebrand disease.
|title=Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain.
|date=07.2018
|date=16.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29767844
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032952
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916080
}}
}}
* {{medline-title
* {{medline-title
|title=The Association of Aging With Von Willebrand Factor Levels and Bleeding Risk in Type 1 Von Willebrand Disease.
|title=Human iPSC-derived astrocytes from ALS patients with mutated [[C9]]ORF72 show increased oxidative stress and neurotoxicity.
|date=04.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28874064
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31787569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921360
}}
}}
* {{medline-title
* {{medline-title
|title=Aging and [[ABO]] blood type influence von Willebrand factor and factor VIII levels through interrelated mechanisms.
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.
|date=05.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26875505
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in platelet function are more profound in women than in men.
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|date=16.07.2015
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26179119
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503960
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
}}
}}
* {{medline-title
* {{medline-title
|title=Von Willebrand factor and aging.
|title=[[C9]]orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons.
|date=09.2014
|date=29.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25151524
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037833
|full-text-url=https://sci-hub.do/10.1055/s-0034-1389079
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705968
}}
}}
==CA4==
* {{medline-title
* {{medline-title
|title=Aging hemostasis: changes to laboratory markers of hemostasis as we age - a narrative review.
|title=Dissociable age and memory relationships with hippocampal subfield volumes in vivo:Data from the Irish Longitudinal Study on Ageing (TILDA).
|date=09.2014
|date=29.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25099191
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31358771
|full-text-url=https://sci-hub.do/10.1055/s-0034-1384631
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662668
}}
}}
* {{medline-title
* {{medline-title
|title=von Willebrand disease and aging: an evolving phenotype.
|title=Aerobic exercise increases hippocampal subfield volumes in younger adults and prevents volume decline in the elderly.
|date=07.2014
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24750783
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30927200
|full-text-url=https://sci-hub.do/10.1111/jth.12586
|full-text-url=https://sci-hub.do/10.1007/s11682-019-00088-6
}}
}}
==ACTN3==
* {{medline-title
* {{medline-title
|title=The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature.
|title=The Volume of Hippocampal Subfields in Relation to Decline of Memory Recall Across the Adult Lifespan.
|date=01.08.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30676214
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30364081
|full-text-url=https://sci-hub.do/10.1123/japa.2018-0155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191512
}}
}}
* {{medline-title
* {{medline-title
|title=Is evolutionary loss our gain? The role of [[ACTN3]] p.Arg577Ter (R577X) genotype in athletic performance, ageing, and disease.
|title=Alzheimer's Disease Biomarkers Have Distinct Associations with Specific Hippocampal Subfield Volumes.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30281865
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320590
|full-text-url=https://sci-hub.do/10.1002/humu.23663
|full-text-url=https://sci-hub.do/10.3233/JAD-180676
}}
}}
* {{medline-title
* {{medline-title
|title=[[ACTN3]] genotype and physical function and frailty in an elderly Chinese population: the Rugao Longevity and Ageing Study.
|title=Age-related changes in cortical and subcortical structures of healthy adult brains: A surface-based morphometry study.
|date=01.05.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29447359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29676856
|full-text-url=https://sci-hub.do/10.1093/ageing/afy007
|full-text-url=https://sci-hub.do/10.1002/jmri.26037
}}
}}
* {{medline-title
* {{medline-title
|title=Muscle-Related Polymorphisms ([[MSTN]] rs1805086 and [[ACTN3]] rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians.
|title=Hippocampal sclerosis, hippocampal neuron loss patterns and TDP-43 in the aged population.
|date=2016
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27861536
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28833898
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115755
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099461
}}
}}
==CBS==
* {{medline-title
* {{medline-title
|title=Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing.
|title=Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity.
|date=09.2016
|date=02.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27294501
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32800520
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983298
|full-text-url=https://sci-hub.do/10.1016/j.redox.2020.101668
}}
}}
* {{medline-title
* {{medline-title
|title=The [[ACTN3]] R577X genotype is associated with muscle function in a Japanese population.
|title=Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase.
|date=04.2015
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761735
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32027885
|full-text-url=https://sci-hub.do/10.1139/apnm-2014-0346
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7657663
}}
}}
* {{medline-title
* {{medline-title
|title=1000 Norms Project: protocol of a cross-sectional study cataloging human variation.
|title=Methionine restriction leads to hyperhomocysteinemia and alters hepatic H S production capacity in Fischer-344 rats.
|date=03.2016
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25733400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30367932
|full-text-url=https://sci-hub.do/10.1016/j.physio.2014.12.002
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.10.004
}}
}}
==AMT==
* {{medline-title
* {{medline-title
|title=A multi-method comparison of autobiographical memory impairments amongst younger and older adults.
|title=Human Cord Blood Serum-Derived [[APP]] α-Secretase Cleavage Activity is Mediated by C1 Complement.
|date=12.03.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162531
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29871524
|full-text-url=https://sci-hub.do/10.1080/13607863.2020.1729338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020233
}}
}}
* {{medline-title
* {{medline-title
|title=Autobiographical Memory From Different Life Stages in Individuals With Obstructive Sleep Apnea.
|title=Dietary and Endocrine Regulation of Endogenous Hydrogen Sulfide Production: Implications for Longevity.
|date=03.2019
|date=01.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29634343
|full-text-url=https://sci-hub.do/10.1017/S1355617718001091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930795
}}
}}
* {{medline-title
* {{medline-title
|title=Fatigue in Younger and Older Drivers: Effectiveness of an Alertness-Maintaining Task.
|title=Nitration-mediated deficiency of cystathionine β-synthase activity accelerates the progression of hyperhomocysteinemia.
|date=09.2017
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28510495
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29102635
|full-text-url=https://sci-hub.do/10.1177/0018720817706811
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.10.389
}}
}}
==CD47==
* {{medline-title
* {{medline-title
|title=Reduced specificity and enhanced subjective experience of future thinking in ageing: the influence of avoidance and emotion-regulation strategies.
|title=Aging-associated changes in [[CD47]] arrangement and interaction with thrombospondin-1 on red blood cells visualized by super-resolution imaging.
|date=01.2018
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28470139
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32866348
|full-text-url=https://sci-hub.do/10.1080/09658211.2017.1322108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576236
}}
}}
* {{medline-title
* {{medline-title
|title=Evaluation of delirium screening tools in geriatric medical inpatients: a diagnostic test accuracy study.
|title=[[CD47]] Promotes Age-Associated Deterioration in Angiogenesis, Blood Flow and Glucose Homeostasis.
|date=11.2016
|date=15.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27503794
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32679764
|full-text-url=https://sci-hub.do/10.1093/ageing/afw130
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407670
}}
}}
* {{medline-title
* {{medline-title
|title=Falls and other geriatric syndromes in Blantyre, Malawi: a community survey of older adults.
|title=Unique Spatial Immune Profiling in Pancreatic Ductal Adenocarcinoma with Enrichment of Exhausted and Senescent T Cells and Diffused [[CD47]]-SIRPα Expression.
|date=12.2014
|date=07.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26167258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32645996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408661
}}
}}
* {{medline-title
* {{medline-title
|title=Cognitive assessment of elderly inpatients: a clinical audit.
|title=Diabetes Impairs Angiogenesis and Induces Endothelial Cell Senescence by Up-Regulating Thrombospondin-[[CD47]]-Dependent Signaling.
|date=01-04.2015
|date=04.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25759716
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30720765
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335629
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386981
}}
}}
==ATF3==
* {{medline-title
* {{medline-title
|title=[[ATF3]] represses [[PINK1]] gene transcription in lung epithelial cells to control mitochondrial homeostasis.
|title=Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia.
|date=04.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29363258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303009
}}
}}
* {{medline-title
* {{medline-title
|title=p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells.
|title=The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through [[CD47]] and Nox1.
|date=15.09.2017
|date=17.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28765281
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29042481
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679204
}}
}}
==CD5==
* {{medline-title
* {{medline-title
|title=Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival.
|title=Comparative proteomic analysis identifies biomarkers for renal aging.
|date=04.05.2017
|date=06.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28475871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33159023
|full-text-url=https://sci-hub.do/10.1016/j.molcel.2017.04.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695359
}}
}}
* {{medline-title
* {{medline-title
|title=Rutin protects against aging-related metabolic dysfunction.
|title=Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation.
|date=02.2016
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26804783
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930899
|full-text-url=https://sci-hub.do/10.1039/c5fo01036e
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428705
}}
}}
* {{medline-title
* {{medline-title
|title=Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age.
|title=Correlation of cell-surface CD8 levels with function, phenotype and transcriptome of naive CD8 T cells.
|date=2015
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26241743
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30556901
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418459
}}
}}
* {{medline-title
* {{medline-title
|title=Activation of autophagic pathways is related to growth inhibition and senescence in cutaneous squamous cell carcinoma.
|title=Early Generated B-1-Derived B Cells Have the Capacity To Progress To Become Mantle Cell Lymphoma-like Neoplasia in Aged Mice.
|date=10.2014
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25046976
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898964
|full-text-url=https://sci-hub.do/10.1111/exd.12515
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036230
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related brain expression and regulation of the chemokine [[CCL4]]/MIP-1β in APP/PS1 double-transgenic mice.
|title=Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves.
|date=04.2014
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24607962
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977177
|full-text-url=https://sci-hub.do/10.24425/119039
}}
}}
==ATG12==
* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses.
|date=2019
|date=17.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542
}}
}}
==CPM==
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Test-Retest Instability of Temporal Summation and Conditioned Pain Modulation Measures in Older Adults.
|date=09.2017
|date=21.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33083842
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://sci-hub.do/10.1093/pm/pnaa288
}}
}}
* {{medline-title
* {{medline-title
|title=Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats.
|title=Age does not affect sex effect of conditioned pain modulation of pressure and thermal pain across 2 conditioning stimuli.
|date=06.2017
|date=01-02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286171
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32072094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501279
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004505
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging.
|title=The Decline of Endogenous Pain Modulation With Aging: A Meta-Analysis of Temporal Summation and Conditioned Pain Modulation.
|date=26.02.2017
|date=05-06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28238968
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562994
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361683
|full-text-url=https://sci-hub.do/10.1016/j.jpain.2019.09.005
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells.
|title=A keratinocyte and integrated fibroblast culture model for studying particulate matter-induced skin lesions and therapeutic intervention of fucosterol.
|date=02.2017
|date=15.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31376370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116714
}}
}}
* {{medline-title
* {{medline-title
|title=Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts.
|title=Daily physical activity patterns among aging workers: the Finnish Retirement and Aging Study (FIREA).
|date=12.2016
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27825071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099282
|full-text-url=https://sci-hub.do/10.1136/oemed-2018-105266
}}
}}
* {{medline-title
* {{medline-title
|title=Follicle-stimulating hormone promotes age-related endometrial atrophy through cross-talk with transforming growth factor beta signal transduction pathway.
|title=Resting-state functional connectivity predicts neuroticism and extraversion in novel individuals.
|date=04.2015
|date=01.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25393561
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29373729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364840
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827338
}}
}}
==B2M==
==CX3CL1==


* {{medline-title
* {{medline-title
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes.
|title=Two forms of [[CX3CL1]] display differential activity and rescue cognitive deficits in [[CX3CL1]] knockout mice.
|date=03.2019
|date=14.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32410624
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227354
}}
}}
* {{medline-title
* {{medline-title
|title=Association between serum β2-microglobulin levels and frailty in an elderly Chinese population: results from RuLAS.
|title=Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens.
|date=2017
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081654
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652941
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.09.015
}}
}}
* {{medline-title
* {{medline-title
|title=Non-GFR Determinants of Low-Molecular-Weight Serum Protein Filtration Markers in the Elderly: AGES-Kidney and MESA-Kidney.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=09.2017
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28549536
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572311
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
* {{medline-title
* {{medline-title
|title=Association Between Serum β  -Microglobulin Levels and Prevalent and Incident Physical Frailty in Community-Dwelling Older Women.
|title=Surgical Trauma Exacerbates Cognitive Deficits and Neuroinflammation in Aged Rats: The Role of [[CX3CL1]]-[[CX3CR1]] Signaling.
|date=04.2017
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28140452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29939299
|full-text-url=https://sci-hub.do/10.1111/jgs.14733
|full-text-url=https://sci-hub.do/10.1093/jnen/nly051
}}
}}
* {{medline-title
* {{medline-title
|title=A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood.
|title=Repopulating retinal microglia restore endogenous organization and function under [[CX3CL1]]-[[CX3CR1]] regulation.
|date=22.11.2016
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27874859
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750189
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943055
}}
}}
* {{medline-title
* {{medline-title
|title=β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis.
|title=Microglia and Aging: The Role of the [[TREM2]]-DAP12 and [[CX3CL1]]-[[CX3CR1]] Axes.
|date=08.2015
|date=22.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26147761
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29361745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529371
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796261
}}
}}
* {{medline-title
==CXCL2==
|title=Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal.
|date=20.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26003168
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494916
}}
==BIN1==


* {{medline-title
* {{medline-title
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.
|title=Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression.
|date=20.03.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182922
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535784
}}
}}
* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice.
|date=28.03.2018
|date=02.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31048563
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535057
}}
}}
* {{medline-title
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|title=A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.
|date=11.04.2017
|date=19.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30709741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2019.01.002
}}
}}
* {{medline-title
* {{medline-title
|title=Dopamine Receptor Genes Modulate Associative Memory in Old Age.
|title=Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality.
|date=02.2017
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27647283
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30617300
|full-text-url=https://sci-hub.do/10.1162/jocn_a_01048
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375784
}}
}}
* {{medline-title
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles.
|date=04.2016
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
|full-text-url=https://sci-hub.do/10.1620/tjem.245.29
}}
}}
* {{medline-title
* {{medline-title
|title=Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.
|title=Tumor microenvironment in functional adrenocortical adenomas: immune cell infiltration in cortisol-producing adrenocortical adenoma.
|date=04.2015
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25670335
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596893
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391343
|full-text-url=https://sci-hub.do/10.1016/j.humpath.2018.03.016
}}
}}
* {{medline-title
==CXCR2==
|title=The benefits of staying active in old age: physical activity counteracts the negative influence of [[PICALM]], [[BIN1]], and [[CLU]] risk alleles on episodic memory functioning.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24660791
|full-text-url=https://sci-hub.do/10.1037/a0035465
}}
==C9==


* {{medline-title
* {{medline-title
|title=[[C9]]orf72 in myeloid cells suppresses STING-induced inflammation.
|title=CXCL5-[[CXCR2]] signaling is a senescence-associated secretory phenotype in preimplantation embryos.
|date=09.2020
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32814898
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32959976
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576282
}}
}}
* {{medline-title
* {{medline-title
|title=Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain.
|title=Senescence in Wound Repair: Emerging Strategies to Target Chronic Healing Wounds.
|date=16.12.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431694
}}
}}
* {{medline-title
* {{medline-title
|title=Human iPSC-derived astrocytes from ALS patients with mutated [[C9]]ORF72 show increased oxidative stress and neurotoxicity.
|title=Cellular Senescence in Diabetic Wounds: When Too Many Retirees Stress the System.
|date=12.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31787569
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31010531
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921360
|full-text-url=https://sci-hub.do/10.1016/j.jid.2019.02.019
}}
}}
* {{medline-title
* {{medline-title
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.
|title=Elevated Local Senescence in Diabetic Wound Healing Is Linked to Pathological Repair via [[CXCR2]].
|date=2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684552
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829
|full-text-url=https://sci-hub.do/10.1016/j.jid.2019.01.005
}}
}}
* {{medline-title
* {{medline-title
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|title=A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.
|date=07.2019
|date=19.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30709741
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2019.01.002
}}
}}
* {{medline-title
* {{medline-title
|title=[[C9]]orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons.
|title=Chronic Resveratrol Treatment Reduces the Pro-angiogenic Effect of Human Fibroblast "Senescent-Associated Secretory Phenotype" on Endothelial Colony-Forming Cells: The Role of IL8.
|date=29.08.2018
|date=23.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30084946
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705968
|full-text-url=https://sci-hub.do/10.1093/gerona/gly175
}}
}}
==DPP4==
* {{medline-title
* {{medline-title
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|title=Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-[[DPP4]] Axis.
|date=05.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510459
}}
}}
==C9orf72==
* {{medline-title
* {{medline-title
|title=Carriership of two copies of [[C9orf72]] hexanucleotide repeat intermediate-length alleles is a risk factor for ALS in the Finnish population.
|title=Dipeptidyl peptidase-4 inhibition improves endothelial senescence by activating AMPK/SIRT1/Nrf2 signaling pathway.
|date=09.11.2020
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168078
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32251672
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654028
|full-text-url=https://sci-hub.do/10.1016/j.bcp.2020.113951
}}
}}
* {{medline-title
* {{medline-title
|title=[[C9]]orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons.
|title=Molecular crosstalk between Y5 receptor and neuropeptide Y drives liver cancer.
|date=29.08.2018
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31999643
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190991
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related penetrance of the [[C9orf72]] repeat expansion.
|title=Dose rectification of an imbalance between [[DPP4]] and GLP-1 ameliorates chronic stress-related vascular aging and atherosclerosis?
|date=18.05.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28522837
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29220092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437033
|full-text-url=https://sci-hub.do/10.1111/1440-1681.12903
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation age-acceleration is associated with disease duration and age at onset in [[C9orf72]] patients.
|title=Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis.
|date=08.2017
|date=28.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439722
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28963101
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721852
}}
}}
* {{medline-title
* {{medline-title
|title=[[C9orf72]] is required for proper macrophage and microglial function in mice.
|title=Identification of senescent cell surface targetable protein [[DPP4]].
|date=18.03.2016
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26989253
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28877934
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630018
}}
}}
==DRD2==
* {{medline-title
* {{medline-title
|title=Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients.
|title=Cortical thickness mediates the relationship between [[DRD2]] C957T polymorphism and executive function across the adult lifespan.
|date=2016
|date=11.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26919046
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33179159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769150
|full-text-url=https://sci-hub.do/10.1007/s00429-020-02169-5
}}
}}
* {{medline-title
* {{medline-title
|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.
|title=The relationship of age and [[DRD2]] polymorphisms to frontostriatal brain activity and working memory performance.
|date=24.02.2016
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31629117
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.08.022
}}
}}
==CD9==
* {{medline-title
* {{medline-title
|title=Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging.
|title=Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.
|date=01.09.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220525
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29637543
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105503
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of RSC96 Schwann Cell-Derived Exosomes on Proliferation, Senescence, and Apoptosis of Dorsal Root Ganglion Cells In Vitro.
|title=Influence of the [[DRD2]]/ANKK1 Taq1A polymorphism on caudate volume in older adults without dementia.
|date=02.11.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30387453
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564530
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6228118
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995982
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice.
|title=[[FTO]] affects food cravings and interacts with age to influence age-related decline in food cravings.
|date=28.09.2018
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30265241
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233619
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167054
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994171
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA-183-5p Increases with Age in Bone-Derived Extracellular Vesicles, Suppresses Bone Marrow Stromal (Stem) Cell Proliferation, and Induces Stem Cell Senescence.
|title=The [[DRD2]] Taq1A A1 Allele May Magnify the Risk of Alzheimer's in Aging African-Americans.
|date=11.2017
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28363268
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28965318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878111
}}
}}
==EDA==
* {{medline-title
* {{medline-title
|title=Mitochondria defects are involved in lead-acetate-induced adult hematopoietic stem cell decline.
|title=Interplay between aging, lung inflammation/remodeling, and fibronectin [[EDA]] in lung cancer progression.
|date=19.05.2015
|date=01.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25800560
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33222614
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2015.03.007
|full-text-url=https://sci-hub.do/10.1080/15384047.2020.1831372
}}
}}
* {{medline-title
* {{medline-title
|title=Therapeutic efficacy of bone marrow-derived mononuclear cells in diabetic polyneuropathy is impaired with aging or diabetes.
|title=Arousal Detection in Elderly People from Electrodermal Activity Using Musical Stimuli.
|date=03.2015
|date=25.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25802721
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32854302
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506973
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in tissue macrophages precede cardiac functional impairment.
|title=The structure of agricultural microplastics (PT, PU and UF) and their sorption capacities for PAHs and PHE derivates under various salinity and oxidation treatments.
|date=05.2014
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24861132
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31761592
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069267
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2019.113525
}}
* {{medline-title
|title=Effect of storage on quality parameters and phenolic content of Italian extra-virgin olive oils.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30896291
|full-text-url=https://sci-hub.do/10.1080/14786419.2019.1587434
}}
* {{medline-title
|title=Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823768
}}
}}
==CDK5==
* {{medline-title
* {{medline-title
|title=Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence.
|title=An Extract from the Plant [i]Deschampsia antarctica[/i] Protects Fibroblasts from Senescence Induced by Hydrogen Peroxide.
|date=11.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31636448
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894504
|full-text-url=https://sci-hub.do/10.1038/s41593-019-0505-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574316
}}
}}
==FAP==
* {{medline-title
* {{medline-title
|title=CK2 inhibition protects white matter from ischemic injury.
|title=Rapamycin Extends Life Span in Apc  Colon Cancer [[FAP]] Model.
|date=20.11.2018
|date=15.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125643
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33132009
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.08.021
|full-text-url=https://sci-hub.do/10.1016/j.clcc.2020.08.006
}}
}}
* {{medline-title
* {{medline-title
|title=CK2 inhibition confers functional protection to young and aging axons against ischemia by differentially regulating the [[CDK5]] and AKT signaling pathways.
|title=Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors.
|date=06.2019
|date=14.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29944965
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32060352
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2018.05.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021787
}}
}}
* {{medline-title
* {{medline-title
|title=The pathological roles of [[NDRG2]] in Alzheimer's disease, a study using animal models and APPwt-overexpressed cells.
|title=Control of Muscle Fibro-Adipogenic Progenitors by Myogenic Lineage is Altered in Aging and Duchenne Muscular Dystrophy.
|date=08.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28670853
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31865646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492714
|full-text-url=https://sci-hub.do/10.33594/000000196
}}
}}
* {{medline-title
* {{medline-title
|title=[[APOE]]4 Induces Site-Specific Tau Phosphorylation Through Calpain-[[CDK5]] Signaling Pathway in EFAD-Tg Mice.
|title=Higher serum levels of fibroblast growth factor 21 in old patients with cachexia.
|date=2016
|date=07-08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27087442
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30933730
|full-text-url=https://sci-hub.do/10.2174/1567205013666160415154550
|full-text-url=https://sci-hub.do/10.1016/j.nut.2018.11.004
}}
}}
* {{medline-title
* {{medline-title
|title=GENETICS OF HUMAN AGE RELATED DISORDERS.
|title=Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.
|date=2015
|date=07.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26856084
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30686765
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408230
}}
}}
* {{medline-title
* {{medline-title
|title=Surgical stress induces brain-derived neurotrophic factor reduction and postoperative cognitive dysfunction via glucocorticoid receptor phosphorylation in aged mice.
|title=Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development.
|date=05.2015
|date=31.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25611431
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29084951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495659
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662571
}}
}}
==COMP==
==FH==


* {{medline-title
* {{medline-title
|title=Effect of circadian rhythm, age, training and acute lameness on serum concentrations of cartilage oligomeric matrix protein ([[COMP]]) neo-epitope in horses.
|title=Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study.
|date=09.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30739342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33252089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767518
|full-text-url=https://sci-hub.do/10.3233/JAD-201058
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic overexpression of [[COMP]]-Ang1 impairs BM microenvironment and induces senescence of BM HSCs.
|title=Volumetric alterations in the hippocampal subfields of subjects at increased risk of dementia.
|date=15.05.2018
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604278
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32311609
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.210
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.03.006
}}
}}
* {{medline-title
* {{medline-title
|title=Longitudinal Twin Study of Subjective Health: Differences in Genetic and Environmental Components of Variance Across Age and Sex.
|title=Macroscopic hematuria as a risk factor for hypertension in ageing people with hemophilia and a family history of hypertension.
|date=01.01.2020
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32118768
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478422
}}
}}
* {{medline-title
* {{medline-title
|title=Cartilage biomarkers in the osteoarthropathy of alkaptonuria reveal low turnover and accelerated ageing.
|title=LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis.
|date=01.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28028161
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31815695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5188995
|full-text-url=https://sci-hub.do/10.3233/JAD-190742
}}
}}
* {{medline-title
* {{medline-title
|title=Scleraxis Is Essential for Tendon Differentiation by Equine Embryonic Stem Cells and in Equine Fetal Tenocytes.
|title=Sex differences in cholesterol levels from birth to 19 years of age may lead to increased cholesterol burden in females with [[FH]].
|date=15.03.2017
|date=05-06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27899062
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29609857
|full-text-url=https://sci-hub.do/10.1089/scd.2016.0279
|full-text-url=https://sci-hub.do/10.1016/j.jacl.2018.02.021
}}
}}
* {{medline-title
* {{medline-title
|title=Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence.
|title=Association between lipoprotein (a) and proprotein convertase substilisin/kexin type 9 in patients with heterozygous familial hypercholesterolemia: A case-control study.
|date=16.09.2016
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27498005
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129821
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.08.004
|full-text-url=https://sci-hub.do/10.1016/j.metabol.2017.11.004
}}
}}
* {{medline-title
==FNDC5==
|title=Fibrotic-like changes in degenerate human intervertebral discs revealed by quantitative proteomic analysis.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26463451
|full-text-url=https://sci-hub.do/10.1016/j.joca.2015.09.020
}}
==CTSB==


* {{medline-title
* {{medline-title
|title=Myocardial cathepsin D is downregulated in sudden cardiac death.
|title=Irisin Correlates Positively With BMD in a Cohort of Older Adult Patients and Downregulates the Senescent Marker p21 in Osteoblasts.
|date=2020
|date=14.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32176724
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33053231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075574
|full-text-url=https://sci-hub.do/10.1002/jbmr.4192
}}
}}
* {{medline-title
* {{medline-title
|title=A Free Radical-Generating System Regulates Amyloid Oligomers: Involvement of Cathepsin B.
|title=[Investigation of signal molecules in saliva: prospects of application for diagnostics of myocardial infarction and the aging rate of different age people.]
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400084
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31512422
|full-text-url=https://sci-hub.do/10.3233/JAD-170159
 
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Mechanistic complexities of bone loss in Alzheimer's disease: a review.
|date=09.2017
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31184223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://sci-hub.do/10.1080/03008207.2019.1624734
}}
}}
* {{medline-title
* {{medline-title
|title=Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=03.04.2017
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388215
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
* {{medline-title
* {{medline-title
|title=Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function.
|title=Exercise Training Protects Against Aging-Induced Cognitive Dysfunction via Activation of the Hippocampal [[PGC]]-1α/[[FNDC5]]/[[BDNF]] Pathway.
|date=09.08.2016
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27345423
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29971668
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029441
|full-text-url=https://sci-hub.do/10.1007/s12017-018-8500-3
}}
}}
* {{medline-title
* {{medline-title
|title=The association of serum cathepsin B concentration with age-related cardiovascular-renal subclinical state in a healthy Chinese population.
|title=Epistasis, physical capacity-related genes and exceptional longevity: [[FNDC5]] gene interactions with candidate genes FOXOA3 and [[APOE]].
|date=07-08.2016
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27032082
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143599
|full-text-url=https://sci-hub.do/10.1016/j.archger.2016.03.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688477
}}
}}
==FOXO4==
* {{medline-title
* {{medline-title
|title=Decreased serum level of [[HMGB1]] and MyD88 during human aging progress in healthy individuals.
|title=[[FOXO4]]-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice.
|date=04.2016
|date=20.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26130428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31959736
|full-text-url=https://sci-hub.do/10.1007/s40520-015-0402-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053614
}}
}}
==CX3CL1==
* {{medline-title
* {{medline-title
|title=Two forms of [[CX3CL1]] display differential activity and rescue cognitive deficits in [[CX3CL1]] knockout mice.
|title=Introduction to FOXO Biology.
|date=14.05.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32410624
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414140
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227354
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-8900-3_1
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens.
|title=Regulation of cellular senescence via the [[FOXO4]]-p53 axis.
|date=11.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269026
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29683489
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.09.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033032
}}
}}
* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Cellular senescence in the aging and diseased kidney.
|date=11.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29260442
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842195
}}
}}
* {{medline-title
* {{medline-title
|title=Surgical Trauma Exacerbates Cognitive Deficits and Neuroinflammation in Aged Rats: The Role of [[CX3CL1]]-[[CX3CR1]] Signaling.
|title=[Molecular regulative mechanisms of aging and interventional effects of Chinese herbal medicine].
|date=01.08.2018
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29939299
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171222
|full-text-url=https://sci-hub.do/10.1093/jnen/nly051
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20170731.001
}}
}}
* {{medline-title
* {{medline-title
|title=Repopulating retinal microglia restore endogenous organization and function under [[CX3CL1]]-[[CX3CR1]] regulation.
|title=FOXO Transcriptional Factors and Long-Term Living.
|date=03.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750189
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574317
}}
}}
==FST==
* {{medline-title
* {{medline-title
|title=Microglia and Aging: The Role of the [[TREM2]]-DAP12 and [[CX3CL1]]-[[CX3CR1]] Axes.
|title=Comorbid sensorimotor and emotional profiles in the forced swim test immobility and predictive value of a single assay in very old female mice.
|date=22.01.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29361745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30878642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796261
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.03.004
}}
}}
* {{medline-title
* {{medline-title
|title=Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models.
|title=Structure-function multi-scale connectomics reveals a major role of the fronto-striato-thalamic circuit in brain aging.
|date=24.09.2015
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26235435
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30004604
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2015.07.070
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866396
}}
}}
==CXCL2==
* {{medline-title
* {{medline-title
|title=Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression.
|title=Exercise related anxiety-like behaviours are mediated by [[TNF]] receptor signaling, but not depression-like behaviours.
|date=2019
|date=15.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182922
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29800552
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535784
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2018.05.032
}}
}}
* {{medline-title
* {{medline-title
|title=Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice.
|title=Preliminary Data on Some Behavioral Changes Induced by Short-Term Intraperitoneal Oxytocin Administration in Aged Rats.
|date=02.05.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31048563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535057
|full-text-url=https://sci-hub.do/10.24869/psyd.2018.91
}}
}}
* {{medline-title
* {{medline-title
|title=A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=19.02.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30709741
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2019.01.002
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
* {{medline-title
* {{medline-title
|title=Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality.
|title=Desipramine rescues age-related phenotypes in depression-like rats induced by chronic mild stress.
|date=03.2019
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30617300
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28842312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375784
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2017.08.020
}}
}}
==FTO==
* {{medline-title
* {{medline-title
|title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles.
|title=Decreased expression of m A demethylase [[FTO]] in ovarian aging.
|date=05.2018
|date=22.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33221958
|full-text-url=https://sci-hub.do/10.1620/tjem.245.29
|full-text-url=https://sci-hub.do/10.1007/s00404-020-05895-7
}}
}}
* {{medline-title
* {{medline-title
|title=Tumor microenvironment in functional adrenocortical adenomas: immune cell infiltration in cortisol-producing adrenocortical adenoma.
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|date=07.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596893
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|full-text-url=https://sci-hub.do/10.1016/j.humpath.2018.03.016
 
}}
}}
* {{medline-title
* {{medline-title
|title=Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts.
|title=The [[GDF11]]-[[FTO]]-PPARγ axis controls the shift of osteoporotic [[MSC]] fate to adipocyte and inhibits bone formation during osteoporosis.
|date=02.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27845246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279140
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2016.11.003
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.09.015
}}
}}
==CXCR3==
* {{medline-title
* {{medline-title
|title=Senescent hepatocytes enhance natural killer cell activity via the CXCL-10/[[CXCR3]] axis.
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
|date=11.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31616512
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells.
|title=[[FTO]] is involved in Alzheimer's disease by targeting [[TSC1]]-mTOR-Tau signaling.
|date=07.2019
|date=25.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696983
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.02.201
}}
}}
* {{medline-title
* {{medline-title
|title=[[CXCR3]] CD8  T cells with naïve phenotype and high capacity for IFN-γ production are generated during homeostatic T-cell proliferation.
|title=[[FTO]] affects food cravings and interacts with age to influence age-related decline in food cravings.
|date=10.2018
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30058200
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233619
|full-text-url=https://sci-hub.do/10.1002/eji.201747431
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994171
}}
}}
==GATA4==
* {{medline-title
* {{medline-title
|title=The parasite-derived rOv-ASP-1 is an effective antigen-sparing [[CD4]]  T cell-dependent adjuvant for the trivalent inactivated influenza vaccine, and functions in the absence of MyD88 pathway.
|title=Epigenetics and Vascular Senescence-Potential New Therapeutic Targets?
|date=14.06.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29764680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33101015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595497
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556287
}}
}}
* {{medline-title
* {{medline-title
|title=Calorie Restriction Attenuates Terminal Differentiation of Immune Cells.
|title=Prolonged treatment with Y-27632 promotes the senescence of primary human dermal fibroblasts by increasing the expression of IGFBP-5 and transforming them into a CAF-like phenotype.
|date=2016
|date=25.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28127296
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32843583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226962
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485707
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects.
|title=The zinc finger protein [[GATA4]] induces mesenchymal-to-epithelial transition and cellular senescence through the nuclear factor-κB pathway in hepatocellular carcinoma.
|date=10.2016
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27190305
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30995348
|full-text-url=https://sci-hub.do/10.1189/jlb.5A0116-025R
|full-text-url=https://sci-hub.do/10.1111/jgh.14684
}}
}}
* {{medline-title
* {{medline-title
|title=Trafficking phenotype and production of granzyme B by double negative B cells (IgG( )IgD(-)CD27(-)) in the elderly.
|title=Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart.
|date=06.2014
|date=07.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24389059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30663680
|full-text-url=https://sci-hub.do/10.1016/j.exger.2013.12.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207148
}}
}}
==DCN==
* {{medline-title
* {{medline-title
|title=Decorin inhibits the insulin-like growth factor I signaling in bone marrow mesenchymal stem cells of aged humans.
|title=GATA Regulation and Function During the Ovarian Life Cycle.
|date=26.11.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33257596
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544631
|full-text-url=https://sci-hub.do/10.18632/aging.202166
|full-text-url=https://sci-hub.do/10.1016/bs.vh.2018.01.014
}}
}}
* {{medline-title
* {{medline-title
|title=The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity.
|title=Genetic interrogation of replicative senescence uncovers a dual role for [[USP28]] in coordinating the p53 and [[GATA4]] branches of the senescence program.
|date=06.2019
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102684
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089421
|full-text-url=https://sci-hub.do/10.1016/j.diabres.2019.05.009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710139
}}
}}
==GDNF==
* {{medline-title
* {{medline-title
|title=MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway.
|title=GFR-α1 Expression in Substantia Nigra Increases Bilaterally Following Unilateral Striatal [[GDNF]] in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss Following 6-OHDA Nigrostriatal Lesion.
|date=15.04.2019
|date=16.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30987676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31538765
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769
|full-text-url=https://sci-hub.do/10.1021/acschemneuro.9b00291
}}
}}
* {{medline-title
* {{medline-title
|title=Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?: A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats.
|title=The Gender-Biased Effects of Intranasal MPTP Administration on Anhedonic- and Depressive-Like Behaviors in C57BL/6 Mice: the Role of Neurotrophic Factors.
|date=02.2019
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30394964
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310471
|full-text-url=https://sci-hub.do/10.1007/s12640-018-9912-4
}}
}}
* {{medline-title
* {{medline-title
|title=Extracellular proteoglycan decorin maintains human hair follicle stem cells.
|title=Analysis of neurotrophic and antioxidant factors related to midbrain dopamine neuronal loss and brain inflammation in the cerebrospinal fluid of the elderly.
|date=12.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775745
|full-text-url=https://sci-hub.do/10.1111/1346-8138.14678
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.009
}}
}}
* {{medline-title
* {{medline-title
|title=Synaptic Specializations Support Frequency-Independent Purkinje Cell Output from the Cerebellar Cortex.
|title=Glial cell line-derived neurotrophic factor ([[GDNF]]) attenuates the peripheral neuromuscular dysfunction without inhibiting the activation of spinal microglia/monocyte.
|date=20.12.2016
|date=09.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28009294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29743034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870134
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944173
}}
}}
* {{medline-title
* {{medline-title
|title=The aging human cochlear nucleus: Changes in the glial fibrillary acidic protein, intracellular calcium regulatory proteins, GABA neurotransmitter and cholinergic receptor.
|title=Aging-related limit of exercise efficacy on motor decline.
|date=03.2014
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24412669
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29176896
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2013.12.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703560
}}
}}
==DNMT3B==
* {{medline-title
* {{medline-title
|title=Alcohol Extracts From [i]Ganoderma lucidum[/i] Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents.
|title=The Noradrenergic System of Aged [[GDNF]] Heterozygous Mice.
|date=2019
|date=04.2003
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971923
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28853928
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444160
|full-text-url=https://sci-hub.do/10.3727/000000003108746740
}}
}}
==HDAC1==
* {{medline-title
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|title=[[HDAC1]] modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease.
|date=18.03.2019
|date=18.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235043
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Parental Aging During Embryo Development and Adult Life: The Case of Nothobranchius furzeri.
|title=Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.
|date=04.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304310
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30886000
|full-text-url=https://sci-hub.do/10.1089/zeb.2017.1494
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446199
}}
}}
* {{medline-title
* {{medline-title
|title=Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts.
|title=Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies.
|date=01.09.2017
|date=20.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635509
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30341976
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576272
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224233
}}
}}
* {{medline-title
* {{medline-title
|title=Forkhead box A2 regulates biliary heterogeneity and senescence during cholestatic liver injury in mice‡.
|title=Acetylation of PGC1α by Histone Deacetylase 1 Downregulation Is Implicated in Radiation-Induced Senescence of Brain Endothelial Cells.
|date=02.2017
|date=16.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27639079
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30016403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258713
|full-text-url=https://sci-hub.do/10.1093/gerona/gly167
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent expression of [[DNMT1]] and [[DNMT3B]] in PBMCs from a large European population enrolled in the MARK-AGE study.
|title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.
|date=08.2016
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27169697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771
}}
}}
* {{medline-title
* {{medline-title
|title=Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy.
|title=Ablation of toll-like receptor 4 attenuates aging-induced myocardial remodeling and contractile dysfunction through NCoRI-[[HDAC1]]-mediated regulation of autophagy.
|date=10.2016
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27147278
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660306
|full-text-url=https://sci-hub.do/10.1111/ejh.12771
|full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2018.04.009
}}
}}
==FAAH==
==HDAC2==


* {{medline-title
* {{medline-title
|title=Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice.
|title=EEF1A1 deacetylation enables transcriptional activation of remyelination.
|date=02.2020
|date=09.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32095523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32647127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015690
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347577
}}
}}
* {{medline-title
* {{medline-title
|title=Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan.
|title=Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16 .
|date=05.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548519
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516428
}}
}}
* {{medline-title
* {{medline-title
|title=Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease.
|title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke.
|date=11.2016
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26976670
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2016.03.015
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016
}}
}}
* {{medline-title
* {{medline-title
|title=Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth.
|title=[[HDAC3]] Regulates the Transition to the Homeostatic Myelinating Schwann Cell State.
|date=08.04.2016
|date=04.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26900150
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30517863
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825023
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293966
}}
}}
* {{medline-title
* {{medline-title
|title=Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development.
|title=Altered modulation of lamin A/C-[[HDAC2]] interaction and p21 expression during oxidative stress response in HGPS.
|date=03.2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26642910
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30109767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156291
}}
}}
* {{medline-title
* {{medline-title
|title=Enhanced microglial activity in [[FAAH]](-/-) animals.
|title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.
|date=01.10.2015
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25534441
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2014.12.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771
}}
}}
* {{medline-title
==IDH2==
|title=Normal aging in rats and pathological aging in human Alzheimer's disease decrease [[FAAH]] activity: modulation by cannabinoid agonists.
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25456842
|full-text-url=https://sci-hub.do/10.1016/j.exger.2014.10.011
}}
==GBA==


* {{medline-title
* {{medline-title
|title=Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease.
|title=Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions.
|date=08.11.2019
|date=10.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31703585
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31503005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842240
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756887
}}
}}
* {{medline-title
* {{medline-title
|title=Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain.
|title=Augmentation of cellular NAD  by [[NQO1]] enzymatic action improves age-related hearing impairment.
|date=07.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29735433
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31353811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015735
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718544
}}
}}
* {{medline-title
* {{medline-title
|title=[[GBA]] mutations in Parkinson disease: earlier death but similar neuropathological features.
|title=Improving Treatment for Myelodysplastic Syndromes Patients.
|date=11.2017
|date=25.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28834018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362079
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657539
|full-text-url=https://sci-hub.do/10.1007/s11864-018-0583-4
}}
}}
* {{medline-title
* {{medline-title
|title=Cognitive and motor functioning in elderly glucocerebrosidase mutation carriers.
|title=Loss of [[IDH2]] Accelerates Age-related Hearing Loss in Male Mice.
|date=10.2017
|date=22.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28728889
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647652
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864918
}}
}}
* {{medline-title
* {{medline-title
|title=Age and gender-specific reference intervals for lysosomal enzymes in dried blood spot samples: A study in Indian population.
|title=[[IDH2]]-deficient mice develop spinal deformities with aging.
|date=10.2017
|date=17.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396248
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29527922
|full-text-url=https://sci-hub.do/10.1016/j.clinbiochem.2017.04.004
|full-text-url=https://sci-hub.do/10.33549/physiolres.933711
}}
}}
* {{medline-title
* {{medline-title
|title=Minos-insertion mutant of the Drosophila [[GBA]] gene homologue showed abnormal phenotypes of climbing ability, sleep and life span with accumulation of hydroxy-glucocerebroside.
|title=Idh2 deficiency accelerates renal dysfunction in aged mice.
|date=30.05.2017
|date=04.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286087
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928092
|full-text-url=https://sci-hub.do/10.1016/j.gene.2017.03.004
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.082
}}
}}
==IGFBP3==
* {{medline-title
* {{medline-title
|title=Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase ([[GBA]]) and alpha-galactosidase A ([[GLA]]) enzymes.
|title=Cellular and Molecular Biomarkers Indicate Premature Aging in Pseudoxanthoma Elasticum Patients.
|date=12.2017
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28098348
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32489700
|full-text-url=https://sci-hub.do/10.1002/jcp.25807
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220280
}}
}}
==GHRH==
* {{medline-title
* {{medline-title
|title=Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone.
|title=Paracrine senescence of human endometrial mesenchymal stem cells: a role for the insulin-like growth factor binding protein 3.
|date=18.05.2020
|date=17.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32422607
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31951594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288930
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053595
}}
}}
* {{medline-title
* {{medline-title
|title=Transcriptomic and metabolomic profiling of long-lived growth hormone releasing hormone knock-out mice: evidence for altered mitochondrial function and amino acid metabolism.
|title=Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging?
|date=23.02.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32091406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156709
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066919
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529819
}}
}}
* {{medline-title
* {{medline-title
|title=Roles of peptides and steroids in sleep disorders.
|title=Blunted satellite cell response is associated with dysregulated IGF-1 expression after exercise with age.
|date=09.2006
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30754093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30062517
|full-text-url=https://sci-hub.do/10.1586/17446651.1.5.609
|full-text-url=https://sci-hub.do/10.1007/s00421-018-3954-4
}}
}}
* {{medline-title
* {{medline-title
|title=Growth Hormone Deficiency: Health and Longevity.
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|date=01.04.2019
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416709
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
}}
}}
* {{medline-title
* {{medline-title
|title=Aromatized Estrogens Amplify Nocturnal Growth Hormone Secretion in Testosterone-Replaced Older Hypogonadal Men.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=01.12.2018
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30032193
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==LBR==
* {{medline-title
* {{medline-title
|title=Bioactive growth hormone in older men and women: It's relationship to immune markers and healthspan.
|title=Lamin B receptor: role on chromatin structure, cellular senescence and possibly aging.
|date=06.2017
|date=31.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28551577
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32726434
|full-text-url=https://sci-hub.do/10.1016/j.ghir.2017.05.002
|full-text-url=https://sci-hub.do/10.1042/BCJ20200165
}}
}}
* {{medline-title
* {{medline-title
|title=The Somatotrope Growth Hormone-Releasing Hormone/Growth Hormone/Insulin-Like Growth Factor-1 Axis in Immunoregulation and Immunosenescence.
|title=The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers.
|date=2017
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28245459
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32173784
|full-text-url=https://sci-hub.do/10.1159/000452913
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125286
}}
}}
==GK==
* {{medline-title
* {{medline-title
|title=Progression of diabetic kidney disease in T2DN rats.
|title=The role of lamin B receptor in the regulation of senescence-associated secretory phenotype (SASP).
|date=01.12.2019
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32126237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960784
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.111927
}}
}}
* {{medline-title
* {{medline-title
|title=Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging.
|title=Lamin B receptor plays a key role in cellular senescence induced by inhibition of the proteasome.
|date=04.2019
|date=11.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30609251
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31825172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413652
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996348
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Reduction of Contractile Responses to Urotensin II Is Seen in Aortas from Wistar Rats but Not from Type 2 Diabetic Goto-Kakizaki Rats.
|title=Lamin B receptor ([[LBR]]) is involved in the induction of cellular senescence in human cells.
|date=04.2017
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27841739
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30615890
|full-text-url=https://sci-hub.do/10.1089/rej.2016.1864
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.01.001
}}
}}
* {{medline-title
* {{medline-title
|title=[STUDY RELATIVE EXPRESSION OF GENES THAT CONTROL GLUCOSE METABOLISM IN THE LIVER IN MICE WITH DEVELOPMENT OF MELANOCORTIN OBESITY].
|title=Consequences of Lamin B1 and Lamin B Receptor Downregulation in Senescence.
|date=06.2015
|date=06.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26470488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415520
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850099
}}
==LOX==


}}
* {{medline-title
* {{medline-title
|title=Delta Cell Hyperplasia in Adult Goto-Kakizaki ([[GK]]/MolTac) Diabetic Rats.
|title=12-[[LOX]] catalyzes the oxidation of 2-arachidonoyl-lysolipids in platelets generating eicosanoid-lysolipids that are attenuated by iPLA γ knockout.
|date=2015
|date=17.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26236746
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32161117
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506919
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170522
}}
}}
* {{medline-title
* {{medline-title
|title=Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes.
|title=Rice DNA-Binding One Zinc Finger 24 (OsDOF24) Delays Leaf Senescence in a Jasmonate-Mediated Pathway.
|date=2014
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25182811
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31135055
|full-text-url=https://sci-hub.do/10.2174/1567202611666140903122801
|full-text-url=https://sci-hub.do/10.1093/pcp/pcz105
}}
}}
* {{medline-title
* {{medline-title
|title=Evidence for cortical neuronal loss in male type 2 diabetic Goto-Kakizaki rats.
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|date=2014
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24643136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|full-text-url=https://sci-hub.do/10.3233/JAD-131958
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
}}
}}
==GLA==
 
* {{medline-title
* {{medline-title
|title=TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25.
|title=Suppression of [[LOX]] activity enhanced seed vigour and longevity of tobacco ([i]Nicotiana tabacum[/i] L.) seeds during storage.
|date=17.05.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769448
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279990
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012510
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161406
}}
}}
* {{medline-title
* {{medline-title
|title=Gamma-linolenic acid ameliorated glycation-induced memory impairment in rats.
|title=Dermal Collagen Stabilization by Polyphenols and Spray Drying as an Encapsulation Strategy.
|date=12.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28545346
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30095055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012036
|full-text-url=https://sci-hub.do/10.2174/1568026618666180810143730
}}
}}
* {{medline-title
* {{medline-title
|title=Age and gender-specific reference intervals for lysosomal enzymes in dried blood spot samples: A study in Indian population.
|title=Oxygenation of polyunsaturated fatty acids and oxidative stress within blood platelets.
|date=10.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396248
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555597
|full-text-url=https://sci-hub.do/10.1016/j.clinbiochem.2017.04.004
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2018.03.005
}}
}}
==MBP==
* {{medline-title
* {{medline-title
|title=Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase ([[GBA]]) and alpha-galactosidase A ([[GLA]]) enzymes.
|title=Demyelination associated with chronic arsenic exposure in Wistar rats.
|date=12.2017
|date=15.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28098348
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32171569
|full-text-url=https://sci-hub.do/10.1002/jcp.25807
|full-text-url=https://sci-hub.do/10.1016/j.taap.2020.114955
}}
}}
* {{medline-title
* {{medline-title
|title=In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant.
|title=Natural killer cells as participants in pathogenesis of rat experimental autoimmune encephalomyelitis (EAE): lessons from research on rats with distinct age and strain.
|date=07.2016
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27081760
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32140045
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050050
}}
}}
* {{medline-title
* {{medline-title
|title=The stimulatory effect of the [[TLR4]]-mediated adjuvant glucopyranosyl lipid A is well preserved in old age.
|title=Whey protein concentrate supplementation protects rat brain against aging-induced oxidative stress and neurodegeneration.
|date=02.2016
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25957253
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29199432
|full-text-url=https://sci-hub.do/10.1007/s10522-015-9576-x
|full-text-url=https://sci-hub.do/10.1139/apnm-2017-0578
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.
|title=Strain specificities in age-related changes in mechanisms promoting and controlling rat spinal cord damage in experimental autoimmune encephalomyelitis.
|date=06.2014
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24823311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29128575
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123862
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.002
}}
* {{medline-title
|title=Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29046699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645602
}}
}}
==HCN4==
* {{medline-title
* {{medline-title
|title=Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels.
|title=Schwann Cell Phenotype Changes in Aging Human Dental Pulp.
|date=05.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288034
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28972819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934612
|full-text-url=https://sci-hub.do/10.1177/0022034517733967
}}
}}
==MMP1==
* {{medline-title
* {{medline-title
|title=Age-dependent down-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 4 causes deterioration of canine sinoatrial node function.
|title=Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts.
|date=01.05.2017
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28369243
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32533368
|full-text-url=https://sci-hub.do/10.1093/abbs/gmx026
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09886-8
}}
}}
* {{medline-title
* {{medline-title
|title=Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes.
|title=A novel multifunctional skin care formulation with a unique blend of antipollution, brightening and antiaging active complexes.
|date=11.11.2015
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31584241
|full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000455
|full-text-url=https://sci-hub.do/10.1111/jocd.13176
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated expression of HCN channel isoforms in rat sinoatrial node.
|title=Seno-destructive smooth muscle cells in the ascending aorta of patients with bicuspid aortic valve disease.
|date=02.2016
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341471
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31078518
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935443
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562112
}}
}}
* {{medline-title
* {{medline-title
|title=Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation.
|title=Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D.
|date=09.2015
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005035
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526032
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850482
}}
}}
* {{medline-title
* {{medline-title
|title=Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse.
|title=Ginsenoside Rh2 Ameliorates Doxorubicin-Induced Senescence Bystander Effect in Breast Carcinoma Cell MDA-[[MB]]-231 and Normal Epithelial Cell MCF-10A.
|date=27.02.2015
|date=12.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761792
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30871042
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352274
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429443
}}
}}
* {{medline-title
* {{medline-title
|title=Association between reversal in the expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel and age-related atrial fibrillation.
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|date=14.11.2014
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25404650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242900
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
}}
}}
==HDAC6==
==MMP9==


* {{medline-title
* {{medline-title
|title=Inhibition of [[HDAC6]] Attenuates Diabetes-Induced Retinal Redox Imbalance and Microangiopathy.
|title=[[EGR1]] promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling.
|date=09.07.2020
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32660051
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201921
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402090
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.06.010
}}
}}
* {{medline-title
* {{medline-title
|title=Cellular senescence is associated with reorganization of the microtubule cytoskeleton.
|title=[Effect of saponins extracted from Panax japonicas on inhibiting myocardial fibrosis by TGF-β1/Smad3 signaling pathway in aging rats].
|date=03.2019
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30599068
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30593247
|full-text-url=https://sci-hub.do/10.1007/s00018-018-2999-1
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180724.006
}}
}}
* {{medline-title
* {{medline-title
|title=2,4‑Di‑tert‑butylphenol, a potential [[HDAC6]] inhibitor, induces senescence and mitotic catastrophe in human gastric adenocarcinoma AGS cells.
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|date=05.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29427610
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2018.02.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
}}
}}
* {{medline-title
* {{medline-title
|title=[[HDAC6]] Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of [[PLIN2]] in Drosophila.
|title=Oxidative stress induces p38MAPK-dependent senescence in the feto-maternal interface cells.
|date=09.10.2017
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28966044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941169
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2017.09.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023622
}}
}}
* {{medline-title
* {{medline-title
|title=The Deacetylase [[HDAC6]] Mediates Endogenous Neuritic Tau Pathology.
|title=Activation of DNA demethylases attenuates aging-associated arterial stiffening and hypertension.
|date=29.08.2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854366
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052484
}}
}}
* {{medline-title
* {{medline-title
|title=Declined Expression of Histone Deacetylase 6 Contributes to Periodontal Ligament Stem Cell Aging.
|title=Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice.
|date=01.2017
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27562218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326316
|full-text-url=https://sci-hub.do/10.1902/jop.2016.160338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823768
}}
* {{medline-title
|title=Non-sirtuin histone deacetylases in the control of cardiac aging.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25791169
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459895
}}
}}
==HFE==
==OGG1==


* {{medline-title
* {{medline-title
|title=Polyphenol Characterization and Skin-Preserving Properties of Hydroalcoholic Flower Extract from [i]Himantoglossum robertianum[/i] (Orchidaceae).
|title=Advanced Age Is Associated with Iron Dyshomeostasis and Mitochondrial DNA Damage in Human Skeletal Muscle.
|date=14.11.2019
|date=27.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31739534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918203
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953082
}}
}}
* {{medline-title
* {{medline-title
|title=Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-[[F10]] cells by inducing senescence.
|title=8-Oxoguanine accumulation in aged female brain impairs neurogenesis in the dentate gyrus and major island of Calleja, causing sexually dimorphic phenotypes.
|date=15.07.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097108
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026482
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.06.008
|full-text-url=https://sci-hub.do/10.1016/j.pneurobio.2019.04.002
}}
}}
* {{medline-title
* {{medline-title
|title=Iron-processing genotypes, nutrient intakes, and cadmium levels in the Normative Aging Study: Evidence of sensitive subpopulations in cadmium risk assessment.
|title=Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
|date=10.2018
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30059941
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735837
|full-text-url=https://sci-hub.do/10.1016/j.envint.2018.06.040
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2019.02.005
}}
}}
* {{medline-title
* {{medline-title
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats].
|date=2016
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180408.005
}}
}}
* {{medline-title
* {{medline-title
|title=Haplotype analysis of the [[HFE]] gene among populations of Northern Eurasia, in patients with metabolic disorders or stomach cancer, and in long-lived people.
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.
|date=17.06.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27317329
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912798
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081
}}
}}
* {{medline-title
* {{medline-title
|title=No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.
|title=DNA damage and telomere length shortening in the peripheral blood leukocytes of 20 years SM-exposed veterans.
|date=06.2016
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946122
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29803135
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2018.05.008
}}
* {{medline-title
|title=Cumulative lead exposure is associated with reduced olfactory recognition performance in elderly men: The Normative Aging Study.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26121922
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523435
}}
}}
==HMOX1==
==PAM==


* {{medline-title
* {{medline-title
|title=Well-aging: A new strategy for skin homeostasis under multi-stressed conditions.
|title=Relationship between patient activation measurement and self-rated health in patients with chronic diseases.
|date=02.2020
|date=04.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31232507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33148185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643260
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|title=Reversal of Age-Related Neuronal Atrophy by α5-GABAA Receptor Positive Allosteric Modulation.
|date=08.2019
|date=17.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33068001
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
|full-text-url=https://sci-hub.do/10.1093/cercor/bhaa310
}}
}}
* {{medline-title
* {{medline-title
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
|title=The ratio of prematurely aging to non-prematurely aging mice cohabiting, conditions their behavior, immunity and lifespan.
|date=2016
|date=15.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32330742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632
|full-text-url=https://sci-hub.do/10.1016/j.jneuroim.2020.577240
}}
}}
* {{medline-title
* {{medline-title
|title=Exercise-induced Nrf2-signaling is impaired in aging.
|title=Oxidative-Inflammatory Stress in Immune Cells from Adult Mice with Premature Aging.
|date=07.2016
|date=12.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27109910
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30759732
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.04.024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387005
}}
}}
* {{medline-title
* {{medline-title
|title=Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence.
|title=Social environment improves immune function and redox state in several organs from prematurely aging female mice and increases their lifespan.
|date=07.2016
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27094468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30255225
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.014
|full-text-url=https://sci-hub.do/10.1007/s10522-018-9774-4
}}
}}
* {{medline-title
* {{medline-title
|title=Neurotherapeutic effects of novel HO-1 inhibitors in vitro and in a transgenic mouse model of Alzheimer's disease.
|title=Synergistic enhancing-memory effect of donepezil and S 47445, an AMPA positive allosteric modulator, in middle-aged and aged mice.
|date=12.2014
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25111043
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167913
|full-text-url=https://sci-hub.do/10.1111/jnc.12927
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847048
}}
* {{medline-title
|title=Astroglial heme oxygenase-1 and the origin of corpora amylacea in aging and degenerating neural tissues.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24440642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020524
}}
}}
==IDE==
==POMC==


* {{medline-title
* {{medline-title
|title=Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
|title=Gpr17 deficiency in [[POMC]] neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding.
|date=2020
|date=14.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32538851
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31611548
|full-text-url=https://sci-hub.do/10.3233/JAD-200308
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791877
}}
}}
* {{medline-title
* {{medline-title
|title=Hyperinsulinemia is associated with increasing insulin secretion but not with decreasing insulin clearance in an age-related metabolic dysfunction mice model.
|title=Congenital Hypothyroidism is Associated With Impairment of the Leptin Signaling Pathway in the Hypothalamus in Male Wistar Animals in Adult Life.
|date=06.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30370604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30943548
|full-text-url=https://sci-hub.do/10.1002/jcp.27667
|full-text-url=https://sci-hub.do/10.1055/a-0876-6007
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of the Interplay Between Genetic and Behavioral Risks on Survival After Age 75.
|title=Age-dependent decline of hypothalamic HIF2α in response to insulin and its contribution to advanced age-associated metabolic disorders in mice.
|date=12.2016
|date=29.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27806189
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30709906
|full-text-url=https://sci-hub.do/10.1111/jgs.14391
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442045
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic factors moderate everyday physical activity effects on executive functions in aging: Evidence from the Victoria Longitudinal Study.
|title=Prss56 expression in the rodent hypothalamus: Inverse correlation with pro-opiomelanocortin suggests oscillatory gene expression in adult rat tanycytes.
|date=01.2016
|date=15.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26710092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30242838
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693634
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196109
}}
}}
* {{medline-title
* {{medline-title
|title=Enhanced Phospholipase A2 Group 3 Expression by Oxidative Stress Decreases the Insulin-Degrading Enzyme.
|title=Chronic treatment with tributyltin induces sexually dimorphic alterations in the hypothalamic [[POMC]] system of adult mice.
|date=2015
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26637123
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30078105
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670075
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2896-9
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of ageing and experimental diabetes on insulin-degrading enzyme expression in male rat tissues.
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2.
|date=08.2015
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25792373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534
|full-text-url=https://sci-hub.do/10.1007/s10522-015-9569-9
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4
}}
}}
* {{medline-title
==RIPK1==
|title=[[IDE]] (rs6583817) polymorphism and pulse pressure are independently and interactively associated with level and change in executive function in older adults.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24660790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069225
}}
==LBR==


* {{medline-title
* {{medline-title
|title=Lamin B receptor: role on chromatin structure, cellular senescence and possibly aging.
|title=Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3.
|date=31.07.2020
|date=18.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32726434
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33206046
|full-text-url=https://sci-hub.do/10.1042/BCJ20200165
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673785
}}
}}
* {{medline-title
* {{medline-title
|title=The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers.
|title=Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma.
|date=03.2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32173784
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31981738
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125286
|full-text-url=https://sci-hub.do/10.1016/j.joca.2020.01.004
}}
}}
* {{medline-title
* {{medline-title
|title=The role of lamin B receptor in the regulation of senescence-associated secretory phenotype (SASP).
|title=RIP kinases as modulators of inflammation and immunity.
|date=01.05.2020
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32126237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.111927
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x
}}
}}
* {{medline-title
* {{medline-title
|title=Lamin B receptor plays a key role in cellular senescence induced by inhibition of the proteasome.
|title=[[TBK1]] Suppresses [[RIPK1]]-Driven Apoptosis and Inflammation during Development and in Aging.
|date=11.12.2019
|date=06.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31825172
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30146158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128749
}}
}}
* {{medline-title
* {{medline-title
|title=Lamin B receptor ([[LBR]]) is involved in the induction of cellular senescence in human cells.
|title=Necroptosis increases with age and is reduced by dietary restriction.
|date=03.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30615890
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696779
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.01.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052392
}}
}}
* {{medline-title
* {{medline-title
|title=Consequences of Lamin B1 and Lamin B Receptor Downregulation in Senescence.
|title=[[RIPK1]]-[[RIPK3]]-[[MLKL]]-dependent necrosis promotes the aging of mouse male reproductive system.
|date=06.02.2018
|date=15.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807105
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850099
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557593
}}
}}
==S100B==
* {{medline-title
* {{medline-title
|title=Overexpression of Lamin B Receptor Results in Impaired Skin Differentiation.
|title=Aging protects rat cortical slices against to oxygen-glucose deprivation induced damage.
|date=2015
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26053873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32064981
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459694
|full-text-url=https://sci-hub.do/10.1080/00207454.2020.1730830
}}
}}
==MMD==
* {{medline-title
* {{medline-title
|title=Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study.
|title=The Role of [[S100B]] in Aerobic Training Efficacy in Older Adults with Mild Vascular Cognitive Impairment: Secondary Analysis of a Randomized Controlled Trial.
|date=22.11.2020
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33266358
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075314
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700674
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2019.04.052
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study.
|title=Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age.
|date=16.09.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32947839
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30927131
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564216
|full-text-url=https://sci-hub.do/10.1007/s10735-019-09820-4
}}
}}
* {{medline-title
* {{medline-title
|title=Impact and Lessons From the Lifestyle Interventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=04.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105353
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187344
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
* {{medline-title
* {{medline-title
|title=Lactobacillus rescues postnatal neurobehavioral and microglial dysfunction in a model of maternal microbiome dysbiosis.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=10.2019
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31351186
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2019.07.025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
* {{medline-title
* {{medline-title
|title=A Case for Promoting Movement Medicine: Preventing Disability in the LIFE Randomized Controlled Trial.
|title=Proteome profiling in the hippocampus, medial prefrontal cortex, and striatum of aging rat.
|date=04.10.2019
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30778518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29981398
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777081
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.002
}}
}}
==SIRT4==
* {{medline-title
* {{medline-title
|title=Determinants of Basal Collaterals in Moyamoya Disease: Clinical and Genetic Factors.
|title=Novel role of the [[SIRT4]]-[[OPA1]] axis in mitochondrial quality control.
|date=2016
|date=23.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27046023
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225445
|full-text-url=https://sci-hub.do/10.1159/000445348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551841
}}
}}
* {{medline-title
* {{medline-title
|title=Antihypertensive Use and the Effect of a Physical Activity Intervention in the Prevention of Major Mobility Disability Among Older Adults: The LIFE Study.
|title=Mitochondrial Function, Metabolic Regulation, and Human Disease Viewed through the Prism of Sirtuin 4 ([[SIRT4]]) Functions.
|date=07.2016
|date=03.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26865496
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30913880
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906322
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889813
}}
}}
==NRAS==
* {{medline-title
|title=Loss of mitochondrial [[SIRT4]] shortens lifespan and leads to a decline in physical activity.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29872013


}}
* {{medline-title
* {{medline-title
|title=Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor.
|title=[[SIRT4]] is essential for metabolic control and meiotic structure during mouse oocyte maturation.
|date=10.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32558183
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29845740
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052465
}}
}}
* {{medline-title
* {{medline-title
|title=STAT3 Relays a Differential Response to Melanoma-Associated [i][[NRAS]][/i] Mutations.
|title=Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas.
|date=02.01.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31906480
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564694
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016650
|full-text-url=https://sci-hub.do/10.1007/s11102-018-0881-7
}}
}}
* {{medline-title
* {{medline-title
|title=Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study.
|title=[[SIRT4]] interacts with [[OPA1]] and regulates mitochondrial quality control and mitophagy.
|date=08.11.2019
|date=29.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31703632
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842226
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680561
}}
}}
==SIRT7==
* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=[[SIRT7]] antagonizes human stem cell aging as a heterochromatin stabilizer.
|date=2017
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32504224
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305295
}}
}}
* {{medline-title
* {{medline-title
|title=ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A.
|title=Spatio-temporal expression profile of sirtuins during aging of the annual fish Nothobranchius furzeri.
|date=24.03.2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28184004
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075496
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377799
|full-text-url=https://sci-hub.do/10.1016/j.gep.2019.05.001
}}
}}
* {{medline-title
* {{medline-title
|title=Trametinib radiosensitises RAS- and [[BRAF]]-mutated melanoma by perturbing cell cycle and inducing senescence.
|title=Advances in Cellular Characterization of the Sirtuin Isoform, [[SIRT7]].
|date=11.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26163092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30510540
|full-text-url=https://sci-hub.do/10.1016/j.radonc.2015.06.026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253933
}}
}}
* {{medline-title
* {{medline-title
|title=Registered report: senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
|title=The epigenetic regulator [[SIRT7]] guards against mammalian cellular senescence induced by ribosomal DNA instability.
|date=26.01.2015
|date=13.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25621566
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383234
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052228
}}
}}
==NRF1==
* {{medline-title
* {{medline-title
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|title=Differential gene expression of sirtuins between somatotropinomas and nonfunctioning pituitary adenomas.
|date=08.07.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29564694
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
|full-text-url=https://sci-hub.do/10.1007/s11102-018-0881-7
}}
}}
* {{medline-title
* {{medline-title
|title=Photobiomodulation and Coenzyme Q  Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice.
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|date=2019
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
}}
}}
==SQSTM1==
* {{medline-title
* {{medline-title
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
|title=The selective autophagy receptor [[SQSTM1]]/p62 improves lifespan and proteostasis in an evolutionarily conserved manner.
|date=01.08.2018
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041473
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138197
}}
}}
* {{medline-title
* {{medline-title
|title=Response of [[BAX]], Bcl-2 Proteins, and [[SIRT1]]/[[PGC]]-1α mRNA Expression to 8-Week Treadmill Running in the Aging Rat Skeletal Muscle.
|title=[[SIRT2]] functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes.
|date=2016
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27526155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31295472
|full-text-url=https://sci-hub.do/10.1007/978-3-319-38810-6_38
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116639
}}
}}
* {{medline-title
* {{medline-title
|title=mTORC1 signaling activates [[NRF1]] to increase cellular proteasome levels.
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|date=2015
|date=07.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26017155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
}}
}}
* {{medline-title
* {{medline-title
|title=Stressed [[SIRT7]]: facing a crossroad of senescence and immortality.
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|date=06.2015
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25970806
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|full-text-url=https://sci-hub.do/10.1111/1440-1681.12423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
}}
}}
* {{medline-title
* {{medline-title
|title=The thyroid hormone receptor β induces DNA damage and premature senescence.
|title=Systemic overexpression of [[SQSTM1]]/p62 accelerates disease onset in a [[SOD1]] -expressing ALS mouse model.
|date=06.01.2014
|date=29.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24395638
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882795
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975400
}}
}}
==NTS==
* {{medline-title
* {{medline-title
|title=Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=08.2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140326
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://sci-hub.do/10.1080/07420528.2019.1613424
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==TLR9==
* {{medline-title
* {{medline-title
|title=Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats.
|title=Age-Associated B Cells.
|date=01.08.2018
|date=26.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31986068
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019141
|full-text-url=https://sci-hub.do/10.1146/annurev-immunol-092419-031130
}}
}}
* {{medline-title
* {{medline-title
|title=Neural processing of basic tastes in healthy young and older adults - an fMRI study.
|title=Inhibition of [[TLR9]] attenuates skeletal muscle fibrosis in aged sarcopenic mice via the p53/SIRT1 pathway.
|date=01.10.2015
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26072251
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31003004
|full-text-url=https://sci-hub.do/10.1016/j.neuroimage.2015.06.017
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.04.008
}}
}}
* {{medline-title
* {{medline-title
|title=eHealth literacy and Web 2.0 health information seeking behaviors among baby boomers and older adults.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=17.03.2015
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25783036
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381816
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
* {{medline-title
* {{medline-title
|title=Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity.
|title=B cell responses to apoptotic cells in MFG-E8-/- mice.
|date=05.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25636077
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30286201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424182
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171925
}}
}}
* {{medline-title
* {{medline-title
|title=Endogenous leptin contributes to baroreflex suppression within the solitary tract nucleus of aged rats.
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|date=01.12.2014
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25260611
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
}}
}}
* {{medline-title
* {{medline-title
|title=Central hydrogen sulphide mediates ventilatory responses to hypercapnia in adult conscious rats.
|title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.
|date=11.2014
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25042027
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400
|full-text-url=https://sci-hub.do/10.1111/apha.12346
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149
}}
}}
==OGT==
==TPR==


* {{medline-title
* {{medline-title
|title=ELT-2 promotes O-GlcNAc transferase [[OGT]]-1 expression to modulate Caenorhabditis elegans lifespan.
|title=Catalytic Performances of Cu/MCM-22 Zeolites with Different Cu Loadings in NH -SCR.
|date=06.07.2020
|date=30.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32628333
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143192
|full-text-url=https://sci-hub.do/10.1002/jcb.29817
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694057
}}
}}
* {{medline-title
* {{medline-title
|title=Neuronal O-GlcNAcylation Improves Cognitive Function in the Aged Mouse Brain.
|title=Do traits of plant species predict the efficacy of species distribution models for finding new occurrences?
|date=21.10.2019
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31588002
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32551077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199460
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297770
}}
}}
* {{medline-title
* {{medline-title
|title=Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor [[JUN]].
|title=In-situ modified the surface of Pt-doped perovskite catalyst for soot oxidation.
|date=31.07.2018
|date=05.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30012597
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31541957
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077742
|full-text-url=https://sci-hub.do/10.1016/j.jhazmat.2019.121210
}}
}}
* {{medline-title
* {{medline-title
|title=O-GlcNAcylation of SKN-1 modulates the lifespan and oxidative stress resistance in Caenorhabditis elegans.
|title=Nuclear pore density controls heterochromatin reorganization during senescence.
|date=08.03.2017
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28272406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30692205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341102
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362808
}}
}}
* {{medline-title
* {{medline-title
|title=O-linked N-acetylglucosamine transferase ([[OGT]]) interacts with the histone chaperone [[HIRA]] complex and regulates nucleosome assembly and cellular senescence.
|title=Spontaneous mutations in [i]CYC8[/i] and [i]MIG1[/i] suppress the short chronological lifespan of budding yeast lacking SNF1/AMPK.
|date=07.06.2016
|date=19.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27217568
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29796388
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988580
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961917
}}
}}
* {{medline-title
* {{medline-title
|title=Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=22.12.2015
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26673325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839001
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
* {{medline-title
==TXNIP==
|title=Dietary vitamin D3 improves postprandial hyperglycemia in aged mice.
|date=22.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25869067
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.04.008
}}
==P2RY12==


* {{medline-title
* {{medline-title
|title=Potential caveats of putative microglia-specific markers for assessment of age-related cerebrovascular neuroinflammation.
|title=Panax notoginseng saponins attenuate neuroinflammation through [[TXNIP]]-mediated NLRP3 inflammasome activation in aging rats.
|date=01.12.2020
|date=10.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33261619
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33176641
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709276
|full-text-url=https://sci-hub.do/10.2174/1389201021999201110204735
}}
}}
* {{medline-title
* {{medline-title
|title=Microglial changes in the early aging stage in a healthy retina and an experimental glaucoma model.
|title=Redox homeostasis and cell cycle activation mediate beta-cell mass expansion in aged, diabetes-prone mice under metabolic stress conditions: Role of thioredoxin-interacting protein ([[TXNIP]]).
|date=2020
|date=07.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32958210
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33128997
|full-text-url=https://sci-hub.do/10.1016/bs.pbr.2020.05.024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589534
}}
}}
* {{medline-title
* {{medline-title
|title=Patterns of Expression of Purinergic Receptor [[P2RY12]], a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains.
|title=[Effect of diabetic induced thioredoxin interacting protein ([[TXNIP]]) on islet cell senescence].
|date=20.01.2020
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31968618
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32744003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014248
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5878.2020.027
}}
}}
* {{medline-title
* {{medline-title
|title=Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
|title=PRMT5-TRIM21 interaction regulates the senescence of osteosarcoma cells by targeting the [[TXNIP]]/p21 axis.
|date=2018
|date=05.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32023548
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041745
}}
}}
* {{medline-title
* {{medline-title
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|title=[[TXNIP]] regulates AKT-mediated cellular senescence by direct interaction under glucose-mediated metabolic stress.
|date=02.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30168649
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260918
}}
}}
* {{medline-title
* {{medline-title
|title=Transcriptomic analysis of purified human cortical microglia reveals age-associated changes.
|title=Enhanced expression of thioredoxin-interacting-protein regulates oxidative DNA damage and aging.
|date=08.2017
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671693
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897613
|full-text-url=https://sci-hub.do/10.1038/nn.4597
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099297
}}
}}
==VIP==
* {{medline-title
* {{medline-title
|title=Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis.
|title=Alterations in Intrinsic and Synaptic Properties of Hippocampal CA1 [[VIP]] Interneurons During Aging.
|date=01.07.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28541408
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33173468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057548
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591401
}}
}}
==PCSK9==
* {{medline-title
* {{medline-title
|title=Lipoprotein removal mechanisms and aging: implications for the cardiovascular health of the elderly.
|title=Nutrition and exercise interventions could ameliorate age-related cognitive decline: a meta-analysis of randomized controlled trials.
|date=04.2020
|date=14.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32011347
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33052590
|full-text-url=https://sci-hub.do/10.1097/MED.0000000000000529
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01730-w
}}
}}
* {{medline-title
* {{medline-title
|title=The role of proprotein convertase subtilisin-kexin type 9 ([[PCSK9]]) in the vascular aging process - is there a link?
|title=Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension.
|date=10.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31708986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140326
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836637
|full-text-url=https://sci-hub.do/10.1080/07420528.2019.1613424
}}
}}
* {{medline-title
* {{medline-title
|title=[[PCSK9]] Inhibitors Show Value for Patients and the US Health Care System.
|title=The Alabama [[VIP]] older driver study rationale and design: examining the relationship between vision impairment and driving using naturalistic driving techniques.
|date=12.2017
|date=07.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29241886
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415670
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929151
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804048
}}
}}
* {{medline-title
* {{medline-title
|title=Association between lipoprotein (a) and proprotein convertase substilisin/kexin type 9 in patients with heterozygous familial hypercholesterolemia: A case-control study.
|title=Aging-Induced Modulation of Pituitary Adenylate Cyclase-Activating Peptide- and Vasoactive Intestinal Peptide-Induced Vasomotor Responses in the Arteries of Mice.
|date=02.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29131060
|full-text-url=https://sci-hub.do/10.1016/j.metabol.2017.11.004
|full-text-url=https://sci-hub.do/10.1159/000481781
}}
}}
* {{medline-title
* {{medline-title
|title=What's next for dyslipidemia management? The 2013 ACC/AHA Guidelines, the NLA recommendations, and beyond.
|title=Ontogeny of Circadian Rhythms and Synchrony in the Suprachiasmatic Nucleus.
|date=05-06.2016
|date=07.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27156942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29054877
|full-text-url=https://sci-hub.do/10.1016/j.japh.2015.12.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815340
}}
}}
==ABO==
* {{medline-title
* {{medline-title
|title=Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice.
|title=Allelic distribution of [i][[ABO]][/i] gene in Chinese centenarians.
|date=15.01.2016
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26592663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33103040
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.11.064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574633
}}
}}
* {{medline-title
* {{medline-title
|title=[[[[PC]]SK9]]: a key modulator of cardiovascular health.
|title=Genetically Determined [[ABO]] Blood Group and its Associations With Health and Disease.
|date=14.03.2014
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24625727
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31969017
|full-text-url=https://sci-hub.do/10.1161/CIRCRESAHA.114.301621
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.119.313658
}}
}}
==PDK1==
* {{medline-title
* {{medline-title
|title=Inhibition of 3-phosphoinositide-dependent protein kinase 1 ([[PDK1]]) can revert cellular senescence in human dermal fibroblasts.
|title=Plasma proteomic and autoantibody profiles reveal the proteomic characteristics involved in longevity families in Bama, China.
|date=08.12.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33229519
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31139026
|full-text-url=https://sci-hub.do/10.1073/pnas.1920338117
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526601
}}
}}
* {{medline-title
* {{medline-title
|title=The Impact of the PI3K/Akt Signaling Pathway in Anxiety and Working Memory in Young and Middle-Aged [[PDK1]] K465E Knock-In Mice.
|title=Recipients with blood group A associated with longer survival rates in cardiac valvular bioprostheses.
|date=2020
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32457586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30878598
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491382
}}
}}
* {{medline-title
* {{medline-title
|title=Vps15 is critical to mediate autophagy in AngII treated HUVECs probably by [[PDK1]]/PKC signaling pathway.
|title=[[ABO]] blood group polymorphism has an impact on prostate, kidney and bladder cancer in association with longevity.
|date=15.09.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31356904
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30061952
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063046
}}
}}
==ACR==
* {{medline-title
* {{medline-title
|title=Acupuncture Administration Improves Cognitive Functions and Alleviates Inflammation and Nuclear Damage by Regulating Phosphatidylinositol 3 Kinase (PI3K)/Phosphoinositol-Dependent Kinase 1 ([[PDK1]])/Novel Protein Kinase C (nPKC)/Rac 1 Signaling Pathway in Senescence-Accelerated Prone 8 (SAM-P8) Mice.
|title=Progenitor cell niche senescence reflects pathology of the parotid salivary gland in primary Sjögren's syndrome.
|date=01.06.2019
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31152645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32159757
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7516109
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species.
|title=Jumping Joints: The Complex Relationship Between Osteoarthritis and Jumping Mechanography.
|date=2017
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28632756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31655874
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994439
}}
}}
* {{medline-title
* {{medline-title
|title=Selective deletion of Pten in theca-interstitial cells leads to androgen excess and ovarian dysfunction in mice.
|title=Hospitalization Risk among Older Adults with Chronic Kidney Disease.
|date=15.03.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28137614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31311014
|full-text-url=https://sci-hub.do/10.1016/j.mce.2017.01.043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726535
}}
}}
* {{medline-title
* {{medline-title
|title=Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging.
|title=Longitudinal association of carotid endothelial shear stress with renal function decline in aging adults with normal renal function: A population-based cohort study.
|date=02.2014
|date=14.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24516402
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30765747
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376032
}}
}}
==PNN==
* {{medline-title
* {{medline-title
|title=Hyaluronan degradation and release of a hyaluronan-aggrecan complex from perineuronal nets in the aged mouse brain.
|title=Albumin-to-creatinine ratio as a predictor of all-cause mortality and hospitalization of congestive heart failure in Chinese elder hypertensive patients with high cardiovascular risks.
|date=28.11.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33253804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30167324
|full-text-url=https://sci-hub.do/10.1016/j.bbagen.2020.129804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109984
}}
}}
==AVP==
* {{medline-title
* {{medline-title
|title=Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex.
|title=Plasma oxytocin and vasopressin levels in young and older men and women: Functional relationships with attachment and cognition.
|date=09.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706367
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31606581
|full-text-url=https://sci-hub.do/10.1007/s12035-019-1499-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943921
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Pathophysiological Mechanisms of Nocturia and Nocturnal Polyuria: The Contribution of Cellular Function, the Urinary Bladder Urothelium, and Circadian Rhythm.
|date=02.2018
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31369749
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://sci-hub.do/10.1016/j.urology.2019.07.020
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent and region-specific alteration of parvalbumin neurons and perineuronal nets in the mouse cerebral cortex.
|title=Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension.
|date=01.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29126935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140326
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2017.11.001
|full-text-url=https://sci-hub.do/10.1080/07420528.2019.1613424
}}
}}
* {{medline-title
* {{medline-title
|title=Brain ageing changes proteoglycan sulfation, rendering perineuronal nets more inhibitory.
|title=The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system.
|date=28.06.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28657900
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29494864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509459
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878011
}}
}}
* {{medline-title
* {{medline-title
|title=Removal of Perineuronal Nets Unlocks Juvenile Plasticity Through Network Mechanisms of Decreased Inhibition and Increased Gamma Activity.
|title=Copeptin and insulin resistance: effect modification by age and 11 β-HSD2 activity in a population-based study.
|date=01.02.2017
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039374
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29235050
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596863
|full-text-url=https://sci-hub.do/10.1007/s40618-017-0807-7
}}
}}
* {{medline-title
==BRD4==
|title=Age-Related Deterioration of Perineuronal Nets in the Primary Auditory Cortex of Mice.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27877127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099154
}}
==PSEN1==


* {{medline-title
* {{medline-title
|title=Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease.
|title=Inhibition of [[BRD4]] triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells.
|date=20.05.2016
|date=20.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27207465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32954665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875608
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701500
}}
}}
* {{medline-title
* {{medline-title
|title=White Matter Abnormalities Track Disease Progression in [[PSEN1]] Autosomal Dominant Alzheimer's Disease.
|title=[[BRD4]] contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake.
|date=2016
|date=11.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26923015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32392533
|full-text-url=https://sci-hub.do/10.3233/JAD-150899
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288959
}}
}}
* {{medline-title
* {{medline-title
|title=Characterization of Amyloid-β Deposits in Bovine Brains.
|title=BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes.
|date=2016
|date=26.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26890772
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31561444
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801956
}}
}}
* {{medline-title
* {{medline-title
|title=Functions of miR-9 and miR-9* during Aging in SAMP8 Mice and Their Possible Mechanisms.
|title=Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence.
|date=06.2015
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26149132
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31265875
|full-text-url=https://sci-hub.do/10.3881/j.issn.1000-503X.2015.03.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159039
}}
}}
* {{medline-title
* {{medline-title
|title=DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease.
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke.
|date=2015
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25933409
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416920
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004
}}
}}
==C5==
* {{medline-title
* {{medline-title
|title=Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study.
|title=The [[C5]]-75 Program: Meeting the Need for Efficient, Pragmatic Frailty Screening and Management in Primary Care.
|date=03.2015
|date=23.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25580592
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32638663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355261
|full-text-url=https://sci-hub.do/10.1017/S0714980820000161
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent, non-cell-autonomous deposition of amyloid from synthesis of β-amyloid by cells other than excitatory neurons.
|title=Can a relatively large spinal cord for the dural sac influence severity of paralysis in elderly patients with cervical spinal cord injury caused by minor trauma?
|date=05.03.2014
|date=26.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24599465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32590805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328921
}}
* {{medline-title
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829
}}
}}
==RIG==
* {{medline-title
* {{medline-title
|title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling.
|title=Longevity of adenovirus vector immunity in mice and its implications for vaccine efficacy.
|date=2017
|date=29.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30266488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200586
}}
}}
* {{medline-title
* {{medline-title
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes.
|title=Generating Rasch-based activity of daily living measures from the Spinal Cord Injury Longitudinal Aging Study.
|date=12.12.2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28895574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941
|full-text-url=https://sci-hub.do/10.1038/sc.2017.99
}}
}}
==C7==
* {{medline-title
* {{medline-title
|title=Random Item Generation Is Affected by Age.
|title=The Vertebral Artery Convergence to the Cervical Spine in Elders.
|date=01.10.2016
|date=30.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27681687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32337923
|full-text-url=https://sci-hub.do/10.1044/2016_JSLHR-L-15-0077
|full-text-url=https://sci-hub.do/10.3897/folmed.61.e39418
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-related renal injury and inflammation are associated with downregulation of Klotho and induction of [[RIG]]-I/NF-κB signaling pathway in senescence-accelerated mice.
|title=Age-related Changes in Cervical Sagittal Alignment: A Radiographic Analysis.
|date=02.2016
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25986237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31261278
|full-text-url=https://sci-hub.do/10.1007/s40520-015-0371-y
|full-text-url=https://sci-hub.do/10.1097/BRS.0000000000003082
}}
}}
* {{medline-title
* {{medline-title
|title=Age changes of human serum polyreactive immunoglobulins (P[[RIG]]) activity.
|title=Early Intravenous Infusion of Mesenchymal Stromal Cells Exerts a Tissue Source Age-Dependent Beneficial Effect on Neurovascular Integrity and Neurobehavioral Recovery After Traumatic Cervical Spinal Cord Injury.
|date=09-10.2014
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25816599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912623
|full-text-url=https://sci-hub.do/10.15407/ubj86.05.151
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591557
}}
}}
* {{medline-title
* {{medline-title
|title=Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors.
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.
|date=06.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25728020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406671
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829
}}
}}
* {{medline-title
* {{medline-title
|title=Attenuation of respiratory syncytial virus-induced and [[RIG]]-I-dependent type I IFN responses in human neonates and very young children.
|title=Twenty-year Longitudinal Follow-up MRI Study of Asymptomatic Volunteers: The Impact of Cervical Alignment on Disk Degeneration.
|date=01.02.2014
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24391215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102637
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1302007
|full-text-url=https://sci-hub.do/10.1097/BSD.0000000000000706
}}
}}
==ROCK1==
==CCL4==


* {{medline-title
* {{medline-title
|title=Disruption of both [[ROCK1]] and [[ROCK2]] genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging.
|title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau.
|date=06.2019
|date=03.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30848941
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529334
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978
}}
}}
* {{medline-title
* {{medline-title
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles.
|date=02.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
|full-text-url=https://sci-hub.do/10.1620/tjem.245.29
}}
}}
* {{medline-title
* {{medline-title
|title=Vascular Smooth Muscle Contractile Function Declines With Age in Skeletal Muscle Feed Arteries.
|title=Human Body Composition and Immunity: Visceral Adipose Tissue Produces IL-15 and Muscle Strength Inversely Correlates with NK Cell Function in Elderly Humans.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30108507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29559978
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845694
}}
}}
* {{medline-title
* {{medline-title
|title=Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1.
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|date=01-02.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27678468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227678
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
}}
}}
* {{medline-title
* {{medline-title
|title=Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis.
|title=Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A  receptor.
|date=14.01.2016
|date=18.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26765561
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29064819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680557
}}
* {{medline-title
|title=Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle.
|date=15.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26468005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606542
}}
* {{medline-title
|title=miR-135a modulates tendon stem/progenitor cell senescence via suppressing [[ROCK1]].
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25460182
|full-text-url=https://sci-hub.do/10.1016/j.bone.2014.11.001
}}
}}
==SLA==
==CCR7==


* {{medline-title
* {{medline-title
|title=Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity.
|title=Are skin senescence and immunosenescence linked within individuals?
|date=14.07.2020
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32540272
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31062498
|full-text-url=https://sci-hub.do/10.1016/j.vaccine.2020.05.085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612632
}}
}}
* {{medline-title
* {{medline-title
|title=Mechanical Anisotropy and Surface Roughness in Additively Manufactured Parts Fabricated by Stereolithography ([[SLA]]) Using Statistical Analysis.
|title=[[CCL21]]/[[CCR7]] axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
|date=30.05.2020
|date=26.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32486137
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30914733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321476
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435673
}}
}}
* {{medline-title
* {{medline-title
|title=The Effect of Age of Titanium Dental Implants on Implant Survival and Marginal Bone Resorption: A 5-Year Retrospective Follow-Up Study.
|title=Low IL-2 Expressing T Cells in Thalassemia Major Patients: Is It Immune Aging.
|date=01.10.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32369581
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30369736
|full-text-url=https://sci-hub.do/10.1563/aaid-joi-D-19-00316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186253
}}
}}
* {{medline-title
* {{medline-title
|title="Spirometric" lung age reference equations: A narrative review.
|title=Abnormalities of age-related T cell senescence in Parkinson's disease.
|date=01.2018
|date=28.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28870870
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29807534
|full-text-url=https://sci-hub.do/10.1016/j.resp.2017.08.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972443
}}
}}
* {{medline-title
* {{medline-title
|title=Relative growth rate in phylogenetically related deciduous and evergreen woody species.
|title=Effects of lifelong training on senescence and mobilization of T lymphocytes in response to acute exercise.
|date=07.2001
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28547465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29461967
|full-text-url=https://sci-hub.do/10.1007/s004420100645
 
}}
}}
==CD163==
* {{medline-title
* {{medline-title
|title=Leaf lifespan as a determinant of leaf structure and function among 23 amazonian tree species.
|title=Complement Inhibition Attenuates Early Erythrolysis in the Hematoma and Brain Injury in Aged Rats.
|date=03.1991
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28313152
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31177985
|full-text-url=https://sci-hub.do/10.1007/BF00317383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591097
}}
}}
* {{medline-title
* {{medline-title
|title=The Performance of Titanium-Zirconium Implants in the Elderly: A Biomechanical Comparative Study in the Minipig.
|title=Increased monocyte activation with age among HIV-infected long term non-progressor children: implications for early treatment initiation.
|date=12.2016
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26834004
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31131542
|full-text-url=https://sci-hub.do/10.1111/cid.12389
|full-text-url=https://sci-hub.do/10.1111/hiv.12751
}}
}}
==SLC6A4==
* {{medline-title
* {{medline-title
|title=The Psilocybin-Telomere Hypothesis: An empirically falsifiable prediction concerning the beneficial neuropsychopharmacological effects of psilocybin on genetic aging.
|title=Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
|date=01.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634774
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297998
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2019.109406
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetics-by-sex interaction for somatization conferred by methylation at the promoter region of [[SLC6A4]] gene.
|title=Age-related M1/M2 phenotype changes in circulating monocytes from healthy/unhealthy individuals.
|date=08.03.2019
|date=08.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30201454
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29885276
|full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2018.09.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046240
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Distinct effect of age, sex, and CMV seropositivity on dendritic cells and monocytes in human blood.
|date=02.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29359459
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://sci-hub.do/10.1111/imcb.1004
}}
}}
==CD69==
* {{medline-title
* {{medline-title
|title=DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor ([[BDNF]]) and oxytocin receptor ([[OXTR]]) genes are associated with anxiety/depression in older women.
|title=CD8 HLADR  Regulatory T Cells Change With Aging: They Increase in Number, but Lose Checkpoint Inhibitory Molecules and Suppressive Function.
|date=2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26175754
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29915580
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485183
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994398
}}
}}
* {{medline-title
* {{medline-title
|title=Role of the serotonin transporter gene locus in the response to S[[SRI]] treatment of major depressive disorder in late life.
|title=Differential Impact of Obesity on [[CD69]] Expression in Individuals with Bipolar Disorder and Healthy Controls.
|date=05.2015
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25827644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29888230
|full-text-url=https://sci-hub.do/10.1177/0269881115578159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981622
}}
}}
* {{medline-title
* {{medline-title
|title=The Impact of Genetics on Physical Resilience and Successful Aging.
|title=An immunological age index in bipolar disorder: A confirmatory factor analysis of putative immunosenescence markers and associations with clinical characteristics.
|date=09.2015
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25818147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29691917
|full-text-url=https://sci-hub.do/10.1177/0898264315577586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877115
}}
}}
* {{medline-title
* {{medline-title
|title=Serotonin transporter polymorphism modifies the association between depressive symptoms and sleep onset latency complaint in elderly people: results from the 'InveCe.Ab' study.
|title=Differences Between Pediatric and Adult T Cell Responses to [i]In Vitro[/i] Staphylococcal Enterotoxin B Stimulation.
|date=04.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25297871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29616025
|full-text-url=https://sci-hub.do/10.1111/jsr.12248
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869216
}}
}}
==SNCA==
* {{medline-title
|title=Associations between immunological function and memory recall in healthy adults.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020639
|full-text-url=https://sci-hub.do/10.1016/j.bandc.2017.10.002
}}
==CD80==


* {{medline-title
* {{medline-title
|title=Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease.
|title=The aging common marmoset's immune system: From junior to senior.
|date=22.11.2019
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31758049
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32246726
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874660
|full-text-url=https://sci-hub.do/10.1002/ajp.23128
}}
}}
* {{medline-title
* {{medline-title
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading.
|title=[i]Akkermansia muciniphila[/i] ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging [i]Ercc1[/i]   mice.
|date=05.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30899315
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408808
}}
}}
* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy.
|date=04.07.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30560130
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287204
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent accumulation of oligomeric [[SNCA]]/α-synuclein from impaired degradation in mutant [[LRRK2]] knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
|title=Age-related M1/M2 phenotype changes in circulating monocytes from healthy/unhealthy individuals.
|date=02.2020
|date=08.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29885276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046240
}}
}}
* {{medline-title
* {{medline-title
|title=Caloric restriction rescues yeast cells from alpha-synuclein toxicity through autophagic control of proteostasis.
|title=Elderly dendritic cells respond to LPS/IFN-γ and [[CD40]]L stimulation despite incomplete maturation.
|date=07.12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530923
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29652910
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326672
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898732
}}
}}
==CD86==
* {{medline-title
* {{medline-title
|title=Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats.
|title=Iso-α-acids, Hop-Derived Bitter Components of Beer, Attenuate Age-Related Inflammation and Cognitive Decline.
|date=06.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286171
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30778295
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501279
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369178
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation levels of α-synuclein intron 1 in the aging brain.
|title=Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells.
|date=12.2015
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26422361
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696983
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.08.028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474
}}
}}
==SOCS3==
* {{medline-title
* {{medline-title
|title=Congenital Hypothyroidism is Associated With Impairment of the Leptin Signaling Pathway in the Hypothalamus in Male Wistar Animals in Adult Life.
|title=One-Year Consumption of a Mediterranean-Like Dietary Pattern With Vitamin D3 Supplements Induced Small Scale but Extensive Changes of Immune Cell Phenotype, Co-receptor Expression and Innate Immune Responses in Healthy Elderly Subjects: Results From the United Kingdom Arm of the NU-AGE Trial.
|date=05.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30943548
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30093866
|full-text-url=https://sci-hub.do/10.1055/a-0876-6007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070774
}}
}}
* {{medline-title
* {{medline-title
|title=Deletion of suppressor of cytokine signaling 3 ([[SOCS3]]) in muscle stem cells does not alter muscle regeneration in mice after injury.
|title=C-Reactive Protein Impairs Dendritic Cell Development, Maturation, and Function: Implications for Peripheral Tolerance.
|date=2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30811469
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29556231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392323
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845098
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related remodeling of the JAK/STAT/SOCS signaling pathway and associated myocardial changes: From histological to molecular level.
|title=Immunoglobulin therapy ameliorates the phenotype and increases lifespan in the severely affected dystrophin-utrophin double knockout mice.
|date=11.2017
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782583
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29255177
|full-text-url=https://sci-hub.do/10.1016/j.aanat.2017.07.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865115
}}
}}
==CDA==
* {{medline-title
* {{medline-title
|title=Gemfibrozil, food and drug administration-approved lipid-lowering drug, increases longevity in mouse model of late infantile neuronal ceroid lipofuscinosis.
|title=Cumulative Dis/Advantage and Health Pattern in Late Life: A Comparison between Genders and Welfare State Regimes.
|date=05.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367435
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in acute central leptin effects on energy balance are promoted by obesity.
|title=Does numerical similarity alter age-related distractibility in working memory?
|date=01.12.2016
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27780783
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31483830
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.10.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726243
}}
}}
* {{medline-title
* {{medline-title
|title=Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections.
|title=Can working memory capacity be expanded by boosting working memory updating efficiency in older adults?
|date=01.11.2016
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27694475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30475011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504405
|full-text-url=https://sci-hub.do/10.1037/pag0000311
}}
}}
* {{medline-title
* {{medline-title
|title=[[IL10]]-driven [[STAT3]] signalling in senescent macrophages promotes pathological eye angiogenesis.
|title=Negative Affect Influences Electrophysiological Markers of Visual Working Memory in Mildly Stressed Older Adults.
|date=11.08.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26260587
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29872391
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918330
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972212
}}
}}
==SRC==
* {{medline-title
* {{medline-title
|title=Metabolic characteristics of CD8  T cell subsets in young and aged individuals are not predictive of functionality.
|title=EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development.
|date=05.06.2020
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32504069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175710
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275080
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.10.018
}}
}}
==CLU==
* {{medline-title
* {{medline-title
|title=Overexpression of steroid receptor coactivators alleviates hyperglycemia-induced endothelial cell injury in rats through activating the PI3K/Akt pathway.
|title=Expression of Clusterin suppresses Cr(VI)-induced premature senescence through activation of PI3K/AKT pathway.
|date=05.2019
|date=15.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30089865
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31376806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786429
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2019.109465
}}
}}
* {{medline-title
* {{medline-title
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|title=Informative combination of [[CLU]] rs11136000, serum HDL levels, diabetes, and age as a new piece of puzzle-picture of predictive medicine for cognitive disorders.
|date=2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30560405
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
|full-text-url=https://sci-hub.do/10.1007/s11033-018-4561-5
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic and Environmental Models of Circadian Disruption Link [[SRC]]-2 Function to Hepatic Pathology.
|title=Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
|date=10.2016
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27432117
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248931
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354244
}}
}}
* {{medline-title
* {{medline-title
|title=Conflict-Specific Aging Effects Mainly Manifest in Early Information Processing Stages-An ERP Study with Different Conflict Types.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=2016
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27014059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
* {{medline-title
* {{medline-title
|title=Physical ACtivity facilitation for Elders (P[[ACE]]): study protocol for a randomised controlled trial.
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=13.03.2015
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25872500
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359571
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
==CSF1R==
* {{medline-title
* {{medline-title
|title=Investigating the stability of mcDESPOT myelin water fraction values derived using a stochastic region contraction approach.
|title=[[CSF1R]] inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice.
|date=01.2015
|date=02.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24464472
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32007953
|full-text-url=https://sci-hub.do/10.1002/mrm.25108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041757
}}
}}
==SRM==
* {{medline-title
* {{medline-title
|title=[Geriatric specificities of localized renal cell carcinoma].
|title=Modulation of Microglia by Voluntary Exercise or [[CSF1R]] Inhibition Prevents Age-Related Loss of Functional Motor Units.
|date=11.2019
|date=05.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771769
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31693894
|full-text-url=https://sci-hub.do/10.1016/j.purol.2019.08.281
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.10.003
}}
}}
* {{medline-title
* {{medline-title
|title=A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes.
|title=Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge.
|date=08.2017
|date=26.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28508553
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30477578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863538
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260864
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of tone-vocoding on spatial release from masking for old, hearing-impaired listeners.
|title=Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice.
|date=04.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28464637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30276955
|full-text-url=https://sci-hub.do/10.1121/1.4979593
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260908
}}
}}
* {{medline-title
* {{medline-title
|title=The role of early and late reflections on spatial release from masking: Effects of age and hearing loss.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=03.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28372125
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392074
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==CXCL9==
* {{medline-title
* {{medline-title
|title=Cortical Measures of Binaural Processing Predict Spatial Release from Masking Performance.
|title=[[CXCL9]] and CXCL10 display an age-dependent profile in Chagas patients: a cohort study of aging in Bambui, Brazil.
|date=2017
|date=11.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28377706
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32393333
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359282
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216412
}}
}}
* {{medline-title
* {{medline-title
|title=Release from masking for small spatial separations: Effects of age and hearing loss.
|title=Inflammatory markers and occurrence of falls: Bambuí Cohort Study of Aging.
|date=07.2016
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27475216
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30942277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392088
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474745
}}
}}
* {{medline-title
* {{medline-title
|title=Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes.
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|date=01.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26577303
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853592
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
}}
}}
==TRIM59==
* {{medline-title
* {{medline-title
|title=DNA methylation of the [[ELOVL2]], [[FHL2]], [[KLF14]], C1orf132/MIR29B2C, and [[TRIM59]] genes for age prediction from blood, saliva, and buccal swab samples.
|title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort.
|date=01.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30300865
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006
}}
}}
* {{medline-title
* {{medline-title
|title=Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing.
|title=Predictive value of multiple cytokines and chemokines for mortality in an admixed population: 15-year follow-up of the Bambui-Epigen (Brazil) cohort study of aging.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031222
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.07.007
}}
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=11.2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803133
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.002
}}
}}
==CYP11A1==
* {{medline-title
* {{medline-title
|title=DNA methylation in [[ELOVL2]] and C1orf132 correctly predicted chronological age of individuals from three disease groups.
|title=Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice.
|date=01.2018
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28725932
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576894
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748441
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.12.034
}}
}}
* {{medline-title
* {{medline-title
|title=Independent validation of DNA-based approaches for age prediction in blood.
|title=Morphological rearrangement of the cortical region, in aging ovaries.
|date=07.2017
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28511095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30589059
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.04.020
|full-text-url=https://sci-hub.do/10.14670/HH-18-078
}}
* {{medline-title
|title=Donor age and C1orf132/MIR29B2C determine age-related methylation signature of blood after allogeneic hematopoietic stem cell transplantation.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27602173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012039
}}
}}
* {{medline-title
* {{medline-title
|title=Development of a forensically useful age prediction method based on DNA methylation analysis.
|title=Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice.
|date=07.2015
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26026729
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778464
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2015.05.001
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.05.059
}}
}}
==TSC2==
* {{medline-title
* {{medline-title
|title=AMPK/[[TSC2]]/mTOR pathway regulates replicative senescence of human vascular smooth muscle cells.
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|date=12.2018
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30542441
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257130
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging.
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio).
|date=25.09.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128
}}
}}
==DCN==
* {{medline-title
* {{medline-title
|title=[[FTO]] is involved in Alzheimer's disease by targeting [[TSC1]]-mTOR-Tau signaling.
|title=Decorin inhibits the insulin-like growth factor I signaling in bone marrow mesenchymal stem cells of aged humans.
|date=25.03.2018
|date=26.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501742
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33257596
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.02.201
|full-text-url=https://sci-hub.do/10.18632/aging.202166
}}
}}
* {{medline-title
* {{medline-title
|title=Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner.
|title=The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity.
|date=12.2017
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29023667
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716871
|full-text-url=https://sci-hub.do/10.1016/j.diabres.2019.05.009
}}
}}
* {{medline-title
* {{medline-title
|title=Complex inhibition of autophagy by mitochondrial aldehyde dehydrogenase shortens lifespan and exacerbates cardiac aging.
|title=MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway.
|date=08.2017
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28347844
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30987676
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2017.03.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769
}}
}}
* {{medline-title
* {{medline-title
|title=Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake.
|title=Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?: A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats.
|date=08.2015
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25866088
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30394964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310471
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells.
|title=Extracellular proteoglycan decorin maintains human hair follicle stem cells.
|date=01.08.2014
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24858802
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320452
|full-text-url=https://sci-hub.do/10.1016/j.bcp.2014.05.009
|full-text-url=https://sci-hub.do/10.1111/1346-8138.14678
}}
}}
==UCHL1==
==DNMT1==


* {{medline-title
* {{medline-title
|title=Abolishing [[UCHL1]]'s hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice.
|title=DNA Methyltransferase 1 ([[DNMT1]]) Function Is Implicated in the Age-Related Loss of Cortical Interneurons.
|date=04.11.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33159930
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793592
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2020.113524
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387673
}}
}}
* {{medline-title
* {{medline-title
|title=Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence.
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|date=2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|full-text-url=https://sci-hub.do/10.1159/000468944
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
}}
}}
* {{medline-title
* {{medline-title
|title=Life and death in the trash heap: The ubiquitin proteasome pathway and [[UCHL1]] in brain aging, neurodegenerative disease and cerebral Ischemia.
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
|date=03.2017
|date=05.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27702698
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250550
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005
}}
}}
* {{medline-title
* {{medline-title
|title=Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system.
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells.
|date=07.2016
|date=15.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27260470
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2016.03.008
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of age on expression of spermatogonial markers in bovine testis and isolated cells.
|title=Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating [[DNMT1]] via [[ZEB1]].
|date=07.2016
|date=16.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27180120
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29466247
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2016.04.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842848
}}
}}
==ECD==
* {{medline-title
* {{medline-title
|title=It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and [[UCHL1]] in Alzheimer Disease.
|title=Outcome of Descemet Membrane Endothelial Keratoplasty Using Corneas from Donors ≥80 Years of Age.
|date=2016
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26881020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31837315
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736377
|full-text-url=https://sci-hub.do/10.1016/j.ajo.2019.12.001
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of [[UCHL1]] promotes age-related degenerative changes in the enteric nervous system.
|title=The occurrence and dynamics of polychlorinated hydrocarbons in roe deer ([i]Capreolus capreolus[/i]) in South-western Slovakia.
|date=2014
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24994982
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30729857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063237
|full-text-url=https://sci-hub.do/10.1080/10934529.2019.1574152
}}
}}
==VIM==
* {{medline-title
* {{medline-title
|title=Establishment and characterization of a fibroblast cell line from postmortem skin of an adult Chinese muntjac (Muntiacus reevesi).
|title=Corneal thickness, endothelial cell density, and morphological and morphometric features of corneal endothelial cells in goats.
|date=02.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31898011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30256142
|full-text-url=https://sci-hub.do/10.1007/s11626-019-00422-8
|full-text-url=https://sci-hub.do/10.2460/ajvr.79.10.1087
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of test modality on dynamic exercise biomarkers in children, adolescents, and young adults.
|title=Endothelial cell density and characterization of corneal endothelial cells in the Tawny Owl (Strix aluco) using specular microscopy.
|date=07.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31353834
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29762889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796805
|full-text-url=https://sci-hub.do/10.1111/vop.12578
}}
}}
* {{medline-title
* {{medline-title
|title=Centenarians Overexpress Pluripotency-Related Genes.
|title=An autopsy case report: Differences in radiological images correlate with histology in Erdheim-Chester disease.
|date=16.08.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603831
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
|full-text-url=https://sci-hub.do/10.1111/pin.12663
}}
}}
==EGR1==
* {{medline-title
* {{medline-title
|title=Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells.
|title=Glucocorticoids delay RAF-induced senescence promoted by [[EGR1]].
|date=01.04.2016
|date=22.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27036204
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31371485
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818421
|full-text-url=https://sci-hub.do/10.1242/jcs.230748
}}
}}
* {{medline-title
* {{medline-title
|title=Assessment of Age-Related Differences in Functional Capacity Using the Virtual Reality Functional Capacity Assessment Tool (VRFCAT).
|title=[[EGR1]] promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling.
|date=06.2015
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26618145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201921
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657736
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.06.010
}}
}}
* {{medline-title
* {{medline-title
|title=Reactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=10.2015
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26184673
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1002/pros.23045
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
* {{medline-title
* {{medline-title
|title=Cytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice.
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|date=22.05.2015
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25847236
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505553
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
}}
}}
==XIAP==
* {{medline-title
* {{medline-title
|title=Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and [[XIAP]].
|title=The p16/miR-217/[[EGR1]] pathway modulates age-related tenogenic differentiation in tendon stem/progenitor cells.
|date=01.10.2019
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29036495
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.05.017
|full-text-url=https://sci-hub.do/10.1093/abbs/gmx104
}}
}}
==EPO==
* {{medline-title
* {{medline-title
|title=Modulated electro-hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro.
|title=Regulation of muscle and metabolic physiology by hypothalamic erythropoietin independently of its peripheral action.
|date=08.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31183995
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32029230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938905
}}
}}
* {{medline-title
* {{medline-title
|title=Protective effect of xanthohumol against age-related brain damage.
|title=Red Blood Cell Lifespan Shortening in Patients with Early-Stage Chronic Kidney Disease.
|date=11.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31550724
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011
|full-text-url=https://sci-hub.do/10.1159/000502525
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular modeling in the age of clinical genomics, the enterprise of the next generation.
|title=Age-Dependent Systemic Effects of a Systemic Intermittent Hypoxic Therapy [i]In Vivo[/i].
|date=03.2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28204942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529140
|full-text-url=https://sci-hub.do/10.1089/ham.2018.0113
}}
}}
* {{medline-title
* {{medline-title
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|title=Erythropoietin does not improve fracture healing in aged mice.
|date=10.2016
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30998964
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.04.005
}}
}}
* {{medline-title
* {{medline-title
|title=[[XIAP]]-associating factor 1, a transcriptional target of [[BRD7]], contributes to endothelial cell senescence.
|title=Dose-response relationship of intermittent normobaric hypoxia to stimulate erythropoietin in the context of health promotion in young and old people.
|date=02.02.2016
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802028
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30756167
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868675
|full-text-url=https://sci-hub.do/10.1007/s00421-019-04096-8
}}
}}
==F5==
* {{medline-title
* {{medline-title
|title=Targeting protein neddylation with an [[NEDD8]]-activating enzyme inhibitor [[MLN]]4924 induced apoptosis or senescence in human lymphoma cells.
|title=Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis.
|date=2015
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782162
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32039401
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005566
}}
}}
==ABCA7==
* {{medline-title
* {{medline-title
|title=New genetic players in late-onset Alzheimer's disease: Findings of genome-wide association studies.
|title=Fermentation of Blackberry with [i]L. plantarum[/i] JBMI [[F5]] Enhance the Protection Effect on UVB-Mediated Photoaging in Human Foreskin Fibroblast and Hairless Mice through Regulation of MAPK/NF-κB Signaling.
|date=08.2018
|date=11.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30381536
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31614689
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835613
}}
}}
* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing.
|date=16.08.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031222
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.07.007
}}
}}
* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=Multigenerational effects of 4-methylbenzylidene camphor (4-MBC) on the survival, development and reproduction of the marine copepod Tigriopus japonicus.
|date=28.03.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172130
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://sci-hub.do/10.1016/j.aquatox.2017.11.008
}}
}}
* {{medline-title
* {{medline-title
|title=Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28269768
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://sci-hub.do/10.3233/JAD-160774
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==FGFR1==
* {{medline-title
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|title=Alignment of Alzheimer's disease amyloid β-peptide and klotho.
|date=11.04.2017
|date=11-12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32999998
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521834
}}
}}
* {{medline-title
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|title=Satellite cell-specific ablation of Cdon impairs integrin activation, FGF signalling, and muscle regeneration.
|date=04.2016
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32103583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432598
}}
}}
==AGA==
* {{medline-title
* {{medline-title
|title=Relationship between androgenic alopecia and white matter hyperintensities in apparently healthy subjects.
|title=Systemic administration of a fibroblast growth factor receptor 1 agonist rescues the cognitive deficit in aged socially isolated rats.
|date=04.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928883
|full-text-url=https://sci-hub.do/10.1007/s11682-019-00147-y
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.02.011
}}
}}
* {{medline-title
* {{medline-title
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|title=Impact of aging and caloric restriction on fibroblast growth factor 21 signaling in rat white adipose tissue.
|date=2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30620889
 
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.001
}}
}}
* {{medline-title
* {{medline-title
|title=The Impact of Being Born Preterm or Small for Gestational Age on Early Vascular Aging in Adolescents.
|title=Activity-dependent neuronal Klotho enhances astrocytic aerobic glycolysis.
|date=10.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29960764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29493420
|full-text-url=https://sci-hub.do/10.1016/j.jpeds.2018.05.056
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681535
}}
}}
==FSHR==
* {{medline-title
* {{medline-title
|title=Adult height of preterm infants: a longitudinal cohort study.
|title=[[FSHR]] ablation induces depression-like behaviors.
|date=06.2017
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27998884
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32203083
|full-text-url=https://sci-hub.do/10.1136/archdischild-2016-310469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468367
}}
}}
* {{medline-title
* {{medline-title
|title=The telomere attrition rate is not accelerated in women born small for gestational age: A birth cohort study.
|title=Direct actions of gonadotropins beyond the reproductive system and their role in human aging and neoplasia [Bezpośrednie działanie gonadotropin poza układem rozrodczym i ich rola w starzeniu się i nowotworzeniu u człowieka].
|date=05.02.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27871926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31681968
|full-text-url=https://sci-hub.do/10.1016/j.gene.2016.11.030
|full-text-url=https://sci-hub.do/10.5603/EP.a2019.0034
}}
}}
* {{medline-title
* {{medline-title
|title=Does prostaglandin D2 hold the cure to male pattern baldness?
|title=Follicle-stimulating hormone promotes renal tubulointerstitial fibrosis in aging women via the AKT/GSK-3β/β-catenin pathway.
|date=04.2014
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24521203
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31243899
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982925
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718534
}}
}}
==ALB==
* {{medline-title
* {{medline-title
|title=Effects of Age on Inflammatory Profiles and Nutrition/Energy Metabolism in Domestic Cats.
|title=Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes.
|date=2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33262938
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503129
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695597
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.08.018
}}
}}
* {{medline-title
* {{medline-title
|title=Blood Chemistry Reference Values for Free-Ranging Asiatic Black Bears ( Ursus thibetanus) by Season, Age, and Sex.
|title=Diurnal rhythm of follicle-stimulating hormone is associated with nonalcoholic fatty liver disease in a Chinese elderly population.
|date=07.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29671714
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29408750
|full-text-url=https://sci-hub.do/10.7589/2017-08-201
|full-text-url=https://sci-hub.do/10.1016/j.ejogrb.2018.01.034
}}
}}
==FUS==
* {{medline-title
* {{medline-title
|title=Higher serum albumin was related with diabetes incidence and the impact of BMI changes: Based on cohort study of 18,384 Chinese male elderly.
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif.
|date=12.2017
|date=29.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29033312
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132
|full-text-url=https://sci-hub.do/10.1016/j.jdiacomp.2017.08.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004
}}
}}
* {{medline-title
* {{medline-title
|title=Estimating the survival advantage based on telomere length and serum biomarkers of aging.
|title=Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis.
|date=01.08.2017
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28764708
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30128653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540222
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1314-3
}}
}}
* {{medline-title
* {{medline-title
|title=HEMATOLOGY AND PLASMA CHEMISTRY OF THE PLOUGHSHARE TORTOISE (ASTROCHELYS YNIPHORA) IN A CAPTIVE BREEDING PROGRAM.
|title=[Development of imaging-based diagnostic procedures for brain protein aging using a mouse model of tauopathy].
|date=03.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28363080
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29998952
|full-text-url=https://sci-hub.do/10.1638/2016-0201.1
|full-text-url=https://sci-hub.do/10.1254/fpj.152.4
}}
}}
* {{medline-title
* {{medline-title
|title=Too old to have children? Lessons from natural fertility populations.
|title=Riluzole does not improve lifespan or motor function in three ALS mouse models.
|date=06.2014
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24676403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29221425
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389129
|full-text-url=https://sci-hub.do/10.1080/21678421.2017.1407796
}}
}}
==AQP1==
* {{medline-title
* {{medline-title
|title=Blue Light Induces Down-Regulation of Aquaporin 1, 3, and 9 in Human Keratinocytes.
|title=Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging.
|date=03.11.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400272
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912896
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596444
}}
}}
==GCA==
* {{medline-title
* {{medline-title
|title=[Age-related changes of water transport by corneal endothelial cells in rats.]
|title=Familial aggregation of longevity in giant cell arteritis and polymyalgia rheumatica.
|date=2017
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322730
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32683496
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591435
}}
}}
* {{medline-title
* {{medline-title
|title=Investigation of the effects of aging on the expression of aquaporin 1 and aquaporin 4 protein in heart tissue.
|title=Interaction between Alcohol Consumption and Apolipoprotein E (ApoE) Genotype with Cognition in Middle-Aged Men.
|date=01.2017
|date=14.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27443479
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32662384
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324856
|full-text-url=https://sci-hub.do/10.1017/S1355617720000570
}}
}}
* {{medline-title
* {{medline-title
|title=Seasonal and Ageing-Depending Changes of Aquaporins 1 and 9 Expression in the Genital Tract of Buffalo Bulls (Bubalus bubalis).
|title=Influence of young adult cognitive ability and additional education on later-life cognition.
|date=08.2016
|date=05.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27260501
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30670647
|full-text-url=https://sci-hub.do/10.1111/rda.12713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369818
}}
}}
* {{medline-title
* {{medline-title
|title=Investigation of age-related changes in the expression of aquaporin-1 and aquaporin-5 in the salivary glands of mice.
|title=Altered effective connectivity anchored in the posterior cingulate cortex and the medial prefrontal cortex in cognitively intact elderly [[APOE]] ε4 carriers: a preliminary study.
|date=09.2016
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27067150
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29549664
|full-text-url=https://sci-hub.do/10.3109/00016489.2016.1165353
|full-text-url=https://sci-hub.do/10.1007/s11682-018-9857-5
}}
}}
* {{medline-title
* {{medline-title
|title=The effects of high doses of nandrolone decanoate and exercise on prostate microvasculature of adult and older rats.
|title=Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal Atrophy, and White Matter Hyperintensities.
|date=15.01.2015
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25447446
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29314393
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2014.11.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932214
}}
}}
==ASPA==
==GHR==


* {{medline-title
* {{medline-title
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|title=Tissue-Specific [[GHR]] Knockout Mice: An Updated Review.
|date=04.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33162937
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581730
}}
}}
* {{medline-title
* {{medline-title
|title=Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system.
|title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver.
|date=09.2016
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27337627
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2016.06.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures.
|title=Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes.
|date=05.2016
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27249102
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503129
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931852
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.08.018
}}
}}
* {{medline-title
* {{medline-title
|title=Plasma Amyloid Beta 1-42 and DNA Methylation Pattern Predict Accelerated Aging in Young Subjects with Down Syndrome.
|title=Effects of rapamycin on growth hormone receptor knockout mice.
|date=12.2016
|date=13.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27234618
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29378959
|full-text-url=https://sci-hub.do/10.1007/s12017-016-8413-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816183
}}
}}
* {{medline-title
* {{medline-title
|title=Developing a DNA methylation assay for human age prediction in blood and bloodstain.
|title=Disruption of the GH receptor gene in adult mice and in insulin sensitive tissues.
|date=07.2015
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25979242
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29198419
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2015.05.007
|full-text-url=https://sci-hub.do/10.1016/j.ghir.2017.11.003
}}
}}
==GHRH==
* {{medline-title
* {{medline-title
|title=Aging of blood can be tracked by DNA methylation changes at just three CpG sites.
|title=Physiological and metabolic features of mice with CRISPR/Cas9-mediated loss-of-function in growth hormone-releasing hormone.
|date=03.02.2014
|date=18.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24490752
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32422607
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288930
}}
}}
==ATRX==
* {{medline-title
* {{medline-title
|title=[[ATRX]]-[[DAXX]] Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains.
|title=Transcriptomic and metabolomic profiling of long-lived growth hormone releasing hormone knock-out mice: evidence for altered mitochondrial function and amino acid metabolism.
|date=09.2019
|date=23.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31361513
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32091406
|full-text-url=https://sci-hub.do/10.1089/dna.2019.4752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066919
}}
}}
* {{medline-title
* {{medline-title
|title=Inactivation of hepatic [[ATRX]] in [i]Atrx[/i] Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine.
|title=Roles of peptides and steroids in sleep disorders.
|date=07.06.2018
|date=09.2006
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883366
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30754093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046231
|full-text-url=https://sci-hub.do/10.1586/17446651.1.5.609
}}
}}
* {{medline-title
* {{medline-title
|title=Mechanistic understanding of the role of [[ATRX]] in senescence provides new insight for combinatorial therapies with [[CDK4]] inhibitors.
|title=Growth Hormone Deficiency: Health and Longevity.
|date=2018
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29404388
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791849
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416709
}}
}}
* {{medline-title
* {{medline-title
|title=GBM-associated mutations and altered protein expression are more common in young patients.
|title=Aromatized Estrogens Amplify Nocturnal Growth Hormone Secretion in Testosterone-Replaced Older Hypogonadal Men.
|date=25.10.2016
|date=01.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30032193
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212797
}}
}}
==GIP==
* {{medline-title
* {{medline-title
|title=Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes.
|title=Absence of [[GIP]] secretion alleviates age-related obesity and insulin resistance.
|date=01.2016
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26577303
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31977316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853592
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040458
}}
}}
* {{medline-title
* {{medline-title
|title=[[MDM2]] turnover and expression of [[ATR]]X determine the choice between quiescence and senescence in response to [[CDK4]] inhibition.
|title=Inhibition of [[GIP]] signaling extends lifespan without caloric restriction.
|date=10.04.2015
|date=11.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25803170
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31003779
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480747
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.036
}}
}}
==BAD==
* {{medline-title
* {{medline-title
|title=I  imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway.
|title=Transcriptional factor Pdx1 is involved in age-related [[GIP]] hypersecretion in mice.
|date=31.10.2020
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33128688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29723041
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00281-2
|full-text-url=https://sci-hub.do/10.1152/ajpgi.00054.2018
}}
}}
* {{medline-title
* {{medline-title
|title=Xanthohumol exerts protective effects in liver alterations associated with aging.
|title=Older Subjects With β-Cell Dysfunction Have an Accentuated Incretin Release.
|date=03.2019
|date=01.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29536163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29672742
|full-text-url=https://sci-hub.do/10.1007/s00394-018-1657-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669818
}}
}}
* {{medline-title
* {{medline-title
|title=Protective effect of xanthohumol against age-related brain damage.
|title=Effect of Age on Blood Glucose and Plasma Insulin, Glucagon, Ghrelin, [[CCK]], [[GIP]], and GLP-1 Responses to Whey Protein Ingestion.
|date=11.2017
|date=21.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29267221
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793230
}}
==GRN==
 
* {{medline-title
|title=Stressful development: Integrating endoderm development, stress, and longevity.
|date=08.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33307045
|full-text-url=https://sci-hub.do/10.1016/j.ydbio.2020.12.002
}}
}}
* {{medline-title
* {{medline-title
|title=Melatonin decreases the expression of inflammation and apoptosis markers in the lung of a senescence-accelerated mice model.
|title=A Scoping Review of the Evidence About the Nurses Improving Care for Healthsystem Elders (NICHE) Program.
|date=03.2016
|date=04.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26656745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31681955
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.11.021
|full-text-url=https://sci-hub.do/10.1093/geront/gnz150
}}
}}
* {{medline-title
* {{medline-title
|title=Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats.
|title=Methods to Investigate the Molecular Basis of Progranulin Actions on Brain and Behavior In Vivo Using Knockout Mice.
|date=2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26594596
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29956280
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642830
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-8559-3_16
}}
}}
* {{medline-title
* {{medline-title
|title=Preliminary cognitive scale of basic and instrumental activities of daily living for dementia and mild cognitive impairment.
|title=Combined Pathologies in FTLD-TDP Types A and C.
|date=2015
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25805061
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29584904
|full-text-url=https://sci-hub.do/10.1080/13803395.2015.1013022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019001
}}
}}
==BLM==
* {{medline-title
* {{medline-title
|title=[Olmesartan inhibits age-associated migration and invasion of human aortic vascular smooth muscle cells by upregulating miR-3133 axis].
|title=A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity.
|date=30.04.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32895132
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29408220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225100
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.01.044
}}
}}
==HDAC6==
* {{medline-title
* {{medline-title
|title=Genomic instability and DNA replication defects in progeroid syndromes.
|title=Inhibition of [[HDAC6]] Attenuates Diabetes-Induced Retinal Redox Imbalance and Microangiopathy.
|date=31.12.2018
|date=09.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29936894
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32660051
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000143
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402090
}}
}}
* {{medline-title
* {{medline-title
|title=Human RecQL4 helicase plays multifaceted roles in the genomic stability of normal and cancer cells.
|title=Cellular senescence is associated with reorganization of the microtubule cytoskeleton.
|date=28.01.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30599068
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2017.10.021
|full-text-url=https://sci-hub.do/10.1007/s00018-018-2999-1
}}
}}
* {{medline-title
* {{medline-title
|title=Bloom's syndrome: Why not premature aging?: A comparison of the [[BLM]] and [[WRN]] helicases.
|title=2,4‑Di‑tert‑butylphenol, a potential [[HDAC6]] inhibitor, induces senescence and mitotic catastrophe in human gastric adenocarcinoma AGS cells.
|date=01.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27238185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29427610
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124422
|full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2018.02.003
}}
}}
* {{medline-title
* {{medline-title
|title=[[NSMCE2]] suppresses cancer and aging in mice independently of its SUMO ligase activity.
|title=[[HDAC6]] Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of [[PLIN2]] in Drosophila.
|date=03.11.2015
|date=09.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26443207
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28966044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641528
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2017.09.001
}}
}}
* {{medline-title
* {{medline-title
|title=Senescence induced by [[RECQL4]] dysfunction contributes to Rothmund-Thomson syndrome features in mice.
|title=The Deacetylase [[HDAC6]] Mediates Endogenous Neuritic Tau Pathology.
|date=15.05.2014
|date=29.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24832598
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047874
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578720
}}
}}
==BMP2==
==HTT==


* {{medline-title
* {{medline-title
|title=Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells.
|title=Biological Aging and the Cellular Pathogenesis of Huntington's Disease.
|date=2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32126555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32417788
|full-text-url=https://sci-hub.do/10.1159/000504298
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7369111
}}
}}
* {{medline-title
* {{medline-title
|title=Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging.
|title=Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models.
|date=03.12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264619
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002862
}}
}}
* {{medline-title
* {{medline-title
|title=Synthesis of Extracellular Pyrophosphate Increases in Vascular Smooth Muscle Cells During Phosphate-Induced Calcification.
|title=Early Neurodegeneration in R6/2 Mice Carrying the Huntington's Disease Mutation with a Super-Expanded CAG Repeat, Despite Normal Lifespan.
|date=09.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29480204
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.311444
|full-text-url=https://sci-hub.do/10.3233/JHD-170265
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Insulin-Like Growth Factor Binding Protein-4 Overexpression Inhibits Osteogenic Differentiation of Rat Mesenchymal Stem Cells.
|title=Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes.
|date=2017
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28595186
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403030
|full-text-url=https://sci-hub.do/10.1159/000477873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857213
}}
}}
* {{medline-title
* {{medline-title
|title=p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner.
|title=Cell-to-cell Transmission of Polyglutamine Aggregates in [i]C. elegans[/i].
|date=06.04.2017
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28382965
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302199
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746497
}}
* {{medline-title
|title=Vaccination with [[DKK1]]-derived peptides promotes bone formation and bone mass in an aged mouse osteoporosis model.
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24907907
|full-text-url=https://sci-hub.do/10.1007/s00223-014-9875-2
}}
}}
==BPIFB4==
==IGF1R==


* {{medline-title
* {{medline-title
|title=New Insights for [[BPIFB4]] in Cardiovascular Therapy.
|title=Comparison of mitochondrial transplantation by using a stamp-type multineedle injector and platelet-rich plasma therapy for hair aging in naturally aging mice.
|date=28.09.2020
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32998388
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32707439
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583974
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2020.110520
}}
}}
* {{medline-title
* {{medline-title
|title=LAV-[[BPIFB4]] associates with reduced frailty in humans and its transfer prevents frailty progression in old mice.
|title=In mice transgenic for [[IGF1]] under keratin-14 promoter, lifespan is decreased and the rates of aging and thymus involution are accelerated.
|date=28.08.2019
|date=13.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31461407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30981207
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738439
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503882
}}
}}
* {{medline-title
* {{medline-title
|title=Longevity-Associated Variant of [[BPIFB4]] Mitigates Monocyte-Mediated Acquired Immune Response.
|title=Insulin/IGF-1 signaling and aging.
|date=13.11.2019
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557473
|full-text-url=https://sci-hub.do/10.1093/gerona/glz036
 
}}
}}
* {{medline-title
* {{medline-title
|title=A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of [[BPIFB4]].
|title=Effect of young exosomes injected in aged mice.
|date=19.10.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30347645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30254438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141108
}}
}}
* {{medline-title
* {{medline-title
|title=The expression of the [[BPI]]FB4 and [[CXCR4]] associates with sustained health in long-living individuals from Cilento-Italy.
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=22.01.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121621
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361669
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
}}
==KEAP1==
* {{medline-title
* {{medline-title
|title=Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis.
|title=NRF2 pathway activation by [[KEAP1]] inhibition attenuates the manifestation of aging phenotypes in salivary glands.
|date=31.07.2015
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26034043
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32590331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496930
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322188
}}
}}
==BRD4==
* {{medline-title
* {{medline-title
|title=Inhibition of [[BRD4]] triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells.
|title=Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds.
|date=20.09.2020
|date=18.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32954665
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424161
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701500
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234996
}}
}}
* {{medline-title
* {{medline-title
|title=[[BRD4]] contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake.
|title=Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression.
|date=11.05.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32392533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182922
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288959
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535784
}}
}}
* {{medline-title
* {{medline-title
|title=BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes.
|title=Systemic overexpression of [[SQSTM1]]/p62 accelerates disease onset in a [[SOD1]] -expressing ALS mouse model.
|date=26.09.2019
|date=29.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31561444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801956
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975400
}}
}}
* {{medline-title
* {{medline-title
|title=Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence.
|title=Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates.
|date=01.10.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31265875
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159039
|full-text-url=https://sci-hub.do/10.1111/nyas.13556
}}
}}
==LMNB1==
* {{medline-title
* {{medline-title
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke.
|title=SIRT1 - a new mammalian substrate of nuclear autophagy.
|date=07.2019
|date=08.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33292048
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004
|full-text-url=https://sci-hub.do/10.1080/15548627.2020.1860541
}}
}}
* {{medline-title
* {{medline-title
|title=Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases.
|title=Cellular senescence as a response to multiwalled carbon nanotube (MWCNT) exposure in human mesothelial cells.
|date=04.11.2016
|date=03.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27650498
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33279583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095428
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111412
}}
}}
==CBL==
* {{medline-title
* {{medline-title
|title=Effects of cerebrolysin on nerve growth factor system in the aging rat brain.
|title=Inflammatory Drivers of Cardiovascular Disease: Molecular Characterization of Senescent Coronary Vascular Smooth Muscle Cells.
|date=2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32523550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701766
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261939
}}
}}
* {{medline-title
* {{medline-title
|title=Skeletal Muscle CAP Expression Increases after Dietary Restriction and Aerobic Training in Women with a History of Gestational Diabetes.
|title=Neuronal [i]Lamin[/i] regulates motor circuit integrity and controls motor function and lifespan.
|date=2016
|date=17.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28989819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628746
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558924
}}
}}
* {{medline-title
* {{medline-title
|title=Intranasal Cerebrolysin Attenuates Learning and Memory Impairments in D-galactose-Induced Senescence in Mice.
|title=KMT1 family methyltransferases regulate heterochromatin-nuclear periphery tethering via histone and non-histone protein methylation.
|date=01.2017
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27894939
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30858340
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.11.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501005
}}
}}
==LPP==
* {{medline-title
* {{medline-title
|title=Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick's disease and fronto-temporal tauopathies.
|title=Effects of lifelong intake of lemon polyphenols on aging and intestinal microbiome in the senescence-accelerated mouse prone 1 (SAMP1).
|date=26.11.2015
|date=06.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26611895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403313
}}
}}
* {{medline-title
* {{medline-title
|title=Cerebrolysin Accelerates Metamorphosis and Attenuates Aging-Accelerating Effect of High Temperature in Drosophila Melanogaster.
|title=Age differences in the neural correlates underlying control of emotional memory: An event-related potential study.
|date=01.10.2014
|date=15.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25798213
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29920247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367862
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2018.06.019
}}
}}
* {{medline-title
* {{medline-title
|title=Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure.
|title=The Influence of Emotional Material on Encoding and Retrieving Intentions: An ERP Study in Younger and Older Adults.
|date=21.07.2014
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25047000
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820342
}}
}}
==CCL20==
* {{medline-title
* {{medline-title
|title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors.
|title=Convergence of BOLD and ERP measures of neural reactivity to emotional faces in children and adolescents with and without anxiety disorders.
|date=06.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272174
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29462655
|full-text-url=https://sci-hub.do/10.1016/j.antiviral.2020.104784
|full-text-url=https://sci-hub.do/10.1016/j.biopsycho.2018.02.006
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly.
|title=Urethral function and histopathology in aged female rats as a stress urinary incontinence model.
|date=02.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29193757
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29266769
|full-text-url=https://sci-hub.do/10.1002/mnfr.201700307
|full-text-url=https://sci-hub.do/10.1111/luts.12209
}}
}}
==MAP2==
* {{medline-title
* {{medline-title
|title=Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists.
|title=Protective effects of ischemic preconditioning against neuronal apoptosis and dendritic injury in the hippocampus are age-dependent.
|date=15.08.2017
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28696254
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32314365
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548610
|full-text-url=https://sci-hub.do/10.1111/jnc.15029
}}
}}
* {{medline-title
* {{medline-title
|title=Interferon-gamma deficiency protects against aging-related goblet cell loss.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=04.10.2016
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27623073
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323102
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
* {{medline-title
* {{medline-title
|title=Age dependent changes in the LPS induced transcriptome of bovine dermal fibroblasts occurs without major changes in the methylome.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=27.01.2015
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25623529
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312471
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
* {{medline-title
* {{medline-title
|title=Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state.
|title=Systemic overexpression of [[SQSTM1]]/p62 accelerates disease onset in a [[SOD1]] -expressing ALS mouse model.
|date=11.2014
|date=29.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24759206
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205198
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975400
}}
}}
==CCR5==
* {{medline-title
* {{medline-title
|title=[Enhancement can do harm].
|title=Long-term treadmill exercise improves memory impairment through restoration of decreased synaptic adhesion molecule 1/2/3 induced by transient cerebral ischemia in the aged gerbil hippocampus.
|date=08-09.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31532388
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29341891
|full-text-url=https://sci-hub.do/10.1051/medsci/2019136
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.01.015
}}
}}
==MECP2==
* {{medline-title
* {{medline-title
|title=[[CCR5]]-∆32 is deleterious in the homozygous state in humans.
|title=Senescence Phenomena and Metabolic Alteration in Mesenchymal Stromal Cells from a Mouse Model of Rett Syndrome.
|date=06.2019
|date=21.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160814
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31117273
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567034
}}
}}
* {{medline-title
* {{medline-title
|title=[[CCR5]] chemokine receptor gene polymorphisms in ocular toxoplasmosis.
|title=A Novel Mecp2  Knock-in Model Displays Similar Behavioral Traits But Distinct Molecular Features Compared to the Mecp2-Null Mouse Implying Precision Medicine for the Treatment of Rett Syndrome.
|date=02.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29221851
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30402709
|full-text-url=https://sci-hub.do/10.1016/j.actatropica.2017.12.012
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1412-2
}}
}}
* {{medline-title
* {{medline-title
|title=Peripheral loss of CD8( ) CD161(  ) TCRVα7·2( ) mucosal-associated invariant T cells in chronic hepatitis C virus-infected patients.
|title=Tsix-Mecp2 female mouse model for Rett syndrome reveals that low-level [[MECP2]] expression extends life and improves neuromotor function.
|date=02.2016
|date=07.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26681320
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038001
|full-text-url=https://sci-hub.do/10.1111/eci.12581
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094149
}}
}}
* {{medline-title
* {{medline-title
|title=Increased susceptibility of [[CD4]]  T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced [[CD4]] and enhanced [[CXCR4]] and [[FAS]] surface expression levels.
|title=Epilepsy in classic Rett syndrome: Course and characteristics in adult age.
|date=09.10.2015
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26452480
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600300
|full-text-url=https://sci-hub.do/10.1016/j.eplepsyres.2018.06.012
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-associated subpopulations of human CD8  T-lymphocytes identified by their [[CD28]] and CD57 phenotypes.
|title=Loss of [[MECP2]] Leads to Activation of P53 and Neuronal Senescence.
|date=11-12.2015
|date=08.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26277688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29742391
|full-text-url=https://sci-hub.do/10.1016/j.archger.2015.08.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995366
}}
}}
==COL1A1==
==MGMT==


* {{medline-title
* {{medline-title
|title=Remodeling process in bone of aged rats in response to resistance training.
|title=Cytotoxic and Senolytic Effects of Methadone in Combination with Temozolomide in Glioblastoma Cells.
|date=01.09.2020
|date=23.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593709
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32977591
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582495
}}
}}
* {{medline-title
* {{medline-title
|title=Diet enrichment with a specific essential free amino acid mixture improves healing of undressed wounds in aged rats.
|title=Profound, durable and [[MGMT]]-independent sensitivity of glioblastoma cells to cyclin-dependent kinase inhibition.
|date=01.10.2017
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28669821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30549269
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.06.020
|full-text-url=https://sci-hub.do/10.1002/ijc.32069
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts.
|title=Influence of aging in the modulation of epigenetic biomarkers of carcinogenesis after exposure to air pollution.
|date=01.06.2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29860068
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.018
}}
}}
* {{medline-title
* {{medline-title
|title=Scleraxis Is Essential for Tendon Differentiation by Equine Embryonic Stem Cells and in Equine Fetal Tenocytes.
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats.
|date=15.03.2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27899062
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930
|full-text-url=https://sci-hub.do/10.1089/scd.2016.0279
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001
}}
}}
* {{medline-title
* {{medline-title
|title=The comparison of microRNA profile of the dermis between the young and elderly.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=05.2016
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26899446
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2016.01.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
* {{medline-title
==MIA==
|title=Molecular differences between stromal cell populations from deciduous and permanent human teeth.
|date=18.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25927523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417277
}}
==CPD==


* {{medline-title
* {{medline-title
|title=Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease.
|title=Age, cohort, and period effects on metamemory beliefs.
|date=05.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470706
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31804113
|full-text-url=https://sci-hub.do/10.1007/s00391-018-1377-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901096
}}
}}
* {{medline-title
* {{medline-title
|title=What Do Clinical Supervisors Require to Teach Residents in Family Medicine How to Care for Seniors?
|title=Memory Age-based Stereotype Threat: Role of Locus of Control and Anxiety.
|date=03.2018
|date=01-02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29310735
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31752597
|full-text-url=https://sci-hub.do/10.1017/S0714980817000460
|full-text-url=https://sci-hub.do/10.1080/0361073X.2019.1693009
}}
}}
* {{medline-title
* {{medline-title
|title=Survey of Australasian geriatricians' satisfaction with, and preferences for, continuing professional development.
|title=Role of melanoma inhibitory activity in melanocyte senescence.
|date=07.2016
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27087018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31172672
|full-text-url=https://sci-hub.do/10.1111/imj.13116
|full-text-url=https://sci-hub.do/10.1111/pcmr.12801
}}
}}
* {{medline-title
* {{medline-title
|title=The aging psychiatrist: lessons from our colleagues in surgery and anaesthesia.
|title=Refining the metamemory in adulthood questionnaire: a 20-item version of change and capacity designed for research and clinical settings.
|date=04.2016
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912470
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30957531
|full-text-url=https://sci-hub.do/10.1177/1039856216632401
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779492
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of donor age and proliferative aging on the phenotype stability of rat aortic smooth muscle cells.
|title=Maternal Immune Activation Alters Adult Behavior, Gut Microbiome and Juvenile Brain Oscillations in Ferrets.
|date=11.2015
|date=09-10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26603458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30406186
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673651
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220580
}}
}}
==MITF==
* {{medline-title
* {{medline-title
|title=Specificity of cytochemical and fluorescence methods of senescence-associated β-galactosidase detection for ageing driven by replication and time.
|title=Thymocid , a Standardized Black Cumin ([i]Nigella sativa[/i]) Seed Extract, Modulates Collagen Cross-Linking, Collagenase and Elastase Activities, and Melanogenesis in Murine B16F10 Melanoma Cells.
|date=08.2014
|date=19.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24878779
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32707654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400895
}}
}}
==CSF1R==
* {{medline-title
* {{medline-title
|title=[[CSF1R]] inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice.
|title=HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth.
|date=02.02.2020
|date=21.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32007953
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32455577
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041757
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281285
}}
}}
* {{medline-title
* {{medline-title
|title=Modulation of Microglia by Voluntary Exercise or [[CSF1R]] Inhibition Prevents Age-Related Loss of Functional Motor Units.
|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells.
|date=05.11.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31693894
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.10.003
|full-text-url=https://sci-hub.do/10.1111/pcmr.12811
}}
}}
* {{medline-title
* {{medline-title
|title=Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge.
|title=H O  promotes the aging process of melanogenesis through modulation of [[MITF]] and Nrf2.
|date=26.11.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30477578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260864
|full-text-url=https://sci-hub.do/10.1007/s11033-019-04708-8
}}
}}
* {{medline-title
* {{medline-title
|title=Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice.
|title=Deregulated [[MITF]] sumoylation: A route to melanoma.
|date=12.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30276955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28868345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260908
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540212
}}
}}
==MMD==
* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study.
|date=06.2018
|date=22.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33266358
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700674
}}
}}
* {{medline-title
* {{medline-title
|title=Pleiotropic effects of extended blockade of [[CSF1]]R signaling in adult mice.
|title=Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study.
|date=08.2014
|date=16.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24652541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32947839
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564216
}}
}}
==CYP11A1==
* {{medline-title
* {{medline-title
|title=Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice.
|title=Impact and Lessons From the Lifestyle Interventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability.
|date=15.04.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576894
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105353
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.12.034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187344
}}
}}
* {{medline-title
* {{medline-title
|title=Morphological rearrangement of the cortical region, in aging ovaries.
|title=Lactobacillus rescues postnatal neurobehavioral and microglial dysfunction in a model of maternal microbiome dysbiosis.
|date=07.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30589059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31351186
|full-text-url=https://sci-hub.do/10.14670/HH-18-078
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2019.07.025
}}
}}
* {{medline-title
* {{medline-title
|title=Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice.
|title=A Case for Promoting Movement Medicine: Preventing Disability in the LIFE Randomized Controlled Trial.
|date=01.08.2018
|date=04.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778464
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30778518
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.05.059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777081
}}
}}
==MTHFR==
* {{medline-title
* {{medline-title
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|title=One-carbon metabolism supplementation improves outcome after stroke in aged male [[MTHFR]]-deficient mice.
|date=14.11.2017
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31525435
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2019.104613
}}
}}
* {{medline-title
* {{medline-title
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio).
|title=One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults.
|date=03.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208817
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.05.013
}}
}}
* {{medline-title
* {{medline-title
|title=Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs.
|title=Dietary Intervention Modifies DNA Methylation Age Assessed by the Epigenetic Clock.
|date=01.03.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28166986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30350398
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2016.11.007
|full-text-url=https://sci-hub.do/10.1002/mnfr.201800092
}}
}}
==CYP1A2==
* {{medline-title
* {{medline-title
|title=Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of [[CYP1A2]]-Mediated Pharmacokinetics in Young and Elderly Chinese Adults.
|title=Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild [[MTHFR]] Deficiency.
|date=07.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767128
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30288696
|full-text-url=https://sci-hub.do/10.1007/s40262-019-00737-5
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1375-3
}}
}}
* {{medline-title
* {{medline-title
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
|title=Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels.
|date=12.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442
|full-text-url=https://sci-hub.do/10.3233/JAD-180032
}}
}}
==NANOG==
* {{medline-title
* {{medline-title
|title=Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits.
|title=Restoring extracellular matrix synthesis in senescent stem cells.
|date=06.2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396010
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287964
|full-text-url=https://sci-hub.do/10.1016/j.ijheh.2017.03.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766659
}}
}}
* {{medline-title
* {{medline-title
|title=Determination of Human Hepatic [[CYP2C8]] and [[CYP1A2]] Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages.
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|date=05.2017
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28228413
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|full-text-url=https://sci-hub.do/10.1124/dmd.116.074583
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
}}
}}
* {{medline-title
* {{medline-title
|title=Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants.
|title=Amnion epithelial cell-derived exosomes induce inflammatory changes in uterine cells.
|date=06.2017
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27995649
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30138617
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239974
}}
}}
* {{medline-title
* {{medline-title
|title=[Age-dependent [[CYP1A2]] gene polymorphism -163C>A in three ethnic groups of Bashkortostan Republic residents].
|title=[[NANOG]] restores the impaired myogenic differentiation potential of skeletal myoblasts after multiple population doublings.
|date=2014
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29245050
 
|full-text-url=https://sci-hub.do/10.1016/j.scr.2017.11.018
}}
}}
==CYP2D6==
* {{medline-title
* {{medline-title
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|title=Some chemotherapeutics-treated colon cancer cells display a specific phenotype being a combination of stem-like and senescent cell features.
|date=05.2019
|date=02.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053388
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790359
}}
}}
==P2RY12==
* {{medline-title
* {{medline-title
|title=[Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug].
|title=Potential caveats of putative microglia-specific markers for assessment of age-related cerebrovascular neuroinflammation.
|date=2018
|date=01.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30175758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33261619
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00114
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709276
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits.
|title=Microglial changes in the early aging stage in a healthy retina and an experimental glaucoma model.
|date=06.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396010
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32958210
|full-text-url=https://sci-hub.do/10.1016/j.ijheh.2017.03.007
|full-text-url=https://sci-hub.do/10.1016/bs.pbr.2020.05.024
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of Ageing on Serum Concentrations of Risperidone and Its Active Metabolite in Patients with Known [[CYP2D6]] Genotype.
|title=Patterns of Expression of Purinergic Receptor [[P2RY12]], a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains.
|date=11.2016
|date=20.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27145399
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31968618
|full-text-url=https://sci-hub.do/10.1111/bcpt.12614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014248
}}
* {{medline-title
|title=Steady-state serum concentrations of venlafaxine in patients with late-life depression. Impact of age, sex and BMI.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25257248
|full-text-url=https://sci-hub.do/10.1007/s00702-014-1317-9
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of age on serum concentrations of venlafaxine and escitalopram in different [[CYP2D6]] and [[CYP2C19]] genotype subgroups.
|title=Age Influences Microglial Activation After Cuprizone-Induced Demyelination.
|date=08.2014
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24858822
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297998
|full-text-url=https://sci-hub.do/10.1007/s00228-014-1696-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739
}}
}}
==CYP2E1==
* {{medline-title
* {{medline-title
|title=DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver.
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|date=06.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32221779
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287002
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
}}
}}
==PER2==
* {{medline-title
* {{medline-title
|title=2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms.
|title=NAD  Controls Circadian Reprogramming through [[PER2]] Nuclear Translocation to Counter Aging.
|date=01.04.2019
|date=04.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30939745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32369735
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479705
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275919
}}
}}
* {{medline-title
* {{medline-title
|title=Neuroprotective Effect of Dioscin on the Aging Brain.
|title=The protective effect of cycloastragenol on aging mouse circadian rhythmic disorder induced by d-galactose.
|date=30.03.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30935017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479446
|full-text-url=https://sci-hub.do/10.1002/jcb.28587
}}
}}
* {{medline-title
* {{medline-title
|title=Cytochrome P450-2E1 is involved in aging-related kidney damage in mice through increased nitroxidative stress.
|title=Investigating circadian clock gene expression in human tendon biopsies from acute exercise and immobilization studies.
|date=11.2017
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28843596
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656532
|full-text-url=https://sci-hub.do/10.1007/s00421-019-04129-2
}}
}}
* {{medline-title
* {{medline-title
|title=Cytochrome P450-2E1 promotes aging-related hepatic steatosis, apoptosis and fibrosis through increased nitroxidative stress.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=02.2016
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26703967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761508
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
* {{medline-title
* {{medline-title
|title=Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures.
|title=Ontogeny of Circadian Rhythms and Synchrony in the Suprachiasmatic Nucleus.
|date=25.12.2015
|date=07.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25795400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29054877
|full-text-url=https://sci-hub.do/10.1016/j.tiv.2015.03.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815340
}}
}}
==DKK1==
==PIK3CA==


* {{medline-title
* {{medline-title
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women.
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|date=07.2019
|date=10.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
}}
}}
* {{medline-title
* {{medline-title
|title=Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling.
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|date=11.06.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080114
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565990
|full-text-url=https://sci-hub.do/10.1002/path.5314
}}
}}
* {{medline-title
* {{medline-title
|title=[Role and alterations of DNA methylation during the aging and cancer].
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient.
|date=01.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7
}}
}}
* {{medline-title
* {{medline-title
|title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway.
|title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]] accompanied with pro-tumorigenic secretome.
|date=2017
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465
|full-text-url=https://sci-hub.do/10.1002/ijc.32153
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating sclerostin and dickkopf-1 levels in ossification of the posterior longitudinal ligament of the spine.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=05.2016
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26040409
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://sci-hub.do/10.1007/s00774-015-0671-5
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
* {{medline-title
==RIPK3==
|title=Vaccination with [[DKK1]]-derived peptides promotes bone formation and bone mass in an aged mouse osteoporosis model.
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24907907
|full-text-url=https://sci-hub.do/10.1007/s00223-014-9875-2
}}
==FGF19==


* {{medline-title
* {{medline-title
|title=Bile acid receptor agonists in primary biliary cholangitis: Regulation of the cholangiocyte secretome and downstream T cell differentiation.
|title=Metformin mediates cardioprotection against aging-induced ischemic necroptosis.
|date=05.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32123836
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31944526
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996959
}}
}}
* {{medline-title
* {{medline-title
|title=Kotho and aging.
|title=A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice.
|date=09.2016
|date=12.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862818
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414664
}}
}}
* {{medline-title
* {{medline-title
|title=The Klotho proteins in health and disease.
|title=RIP kinases as modulators of inflammation and immunity.
|date=01.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615
|full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x
}}
}}
* {{medline-title
* {{medline-title
|title=Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging.
|title=Necroptosis increases with age and is reduced by dietary restriction.
|date=2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765501
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696779
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052392
}}
}}
* {{medline-title
* {{medline-title
|title=A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion.
|title=[[RIPK1]]-[[RIPK3]]-[[MLKL]]-dependent necrosis promotes the aging of mouse male reproductive system.
|date=08.11.2016
|date=15.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27829151
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807105
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557593
}}
* {{medline-title
|title=A preliminary candidate approach identifies the combination of chemerin, fetuin-A, and fibroblast growth factors 19 and 21 as a potential biomarker panel of successful aging.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25911468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409588
}}
}}
==FIS1==
==ROCK2==


* {{medline-title
* {{medline-title
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.
|title=Physical exercise increases ROCK activity in the skeletal muscle of middle-aged rats.
|date=01.02.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32032622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111213
}}
}}
* {{medline-title
* {{medline-title
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.
|title=Disruption of both [[ROCK1]] and [[ROCK2]] genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging.
|date=2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30848941
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529334
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Role of age, Rho-kinase 2 expression, and G protein-mediated signaling in the myogenic response in mouse small mesenteric arteries.
|date=02.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30198176
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129776
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of β-hydroxy-β-methylbutyrate on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults.
|title=Vascular Smooth Muscle Contractile Function Declines With Age in Skeletal Muscle Feed Arteries.
|date=01.11.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28705993
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30108507
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00192.2017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079263
}}
}}
* {{medline-title
* {{medline-title
|title=Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity.
|title=Changes in Cerebral Arteries and Parenchymal Arterioles With Aging: Role of Rho Kinase 2 and Impact of Genetic Background.
|date=03.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27993601
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29531174
|full-text-url=https://sci-hub.do/10.1016/j.mad.2016.12.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897142
}}
* {{medline-title
|title=Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25840089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614869
}}
}}
==FMR1==
==SAG==


* {{medline-title
* {{medline-title
|title=Static and dynamic postural control deficits in aging fragile X mental retardation 1 ([[FMR1]]) gene premutation carriers.
|title=WRKY42 transcription factor positively regulates leaf senescence through modulating SA and ROS synthesis in Arabidopsis thaliana.
|date=21.01.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30665341
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634860
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341725
|full-text-url=https://sci-hub.do/10.1111/tpj.14914
}}
}}
* {{medline-title
* {{medline-title
|title=Aging in Fragile X Premutation Carriers.
|title=Neurogenesis in the inner ear: the zebrafish statoacoustic ganglion provides new neurons from a Neurod/Nestin-positive progenitor pool well into adulthood.
|date=10.2016
|date=10.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27334385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32165493
|full-text-url=https://sci-hub.do/10.1007/s12311-016-0805-x
|full-text-url=https://sci-hub.do/10.1242/dev.176750
}}
}}
* {{medline-title
* {{medline-title
|title=A Majority of FXTAS Cases Present with Intranuclear Inclusions Within Purkinje Cells.
|title=Effects of natural dietary supplementation with Macleaya cordata extract containing sanguinarine on growth performance and gut health of early-weaned piglets.
|date=10.2016
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27108270
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30129225
|full-text-url=https://sci-hub.do/10.1007/s12311-016-0776-y
|full-text-url=https://sci-hub.do/10.1111/jpn.12976
}}
}}
* {{medline-title
* {{medline-title
|title=Regional brain volumes changes in adult male [[FMR1]]-KO mouse on the FVB strain.
|title=Genetic redundancy of senescence-associated transcription factors in Arabidopsis.
|date=24.03.2016
|date=12.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26794591
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29309664
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2016.01.021
|full-text-url=https://sci-hub.do/10.1093/jxb/erx345
}}
}}
* {{medline-title
* {{medline-title
|title=[[FMR1]] premutation is an uncommon explanation for premature ovarian failure in Han Chinese.
|title=Proteomic Investigations of Proteases Involved in Cotyledon Senescence: A Model to Explore the Genotypic Variability of Proteolysis Machinery Associated with Nitrogen Remobilization Efficiency during the Leaf Senescence of Oilseed Rape.
|date=2014
|date=02.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25050920
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29099081
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748564
}}
}}
* {{medline-title
==SMAD3==
|title=Age and CGG-repeat length are associated with neuromotor impairments in at-risk females with the [[FMR1]] premutation.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24814676
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2014.03.018
}}
==FOXP3==


* {{medline-title
* {{medline-title
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|title=Sirtuin 6 deficiency transcriptionally up-regulates TGF-β signaling and induces fibrosis in mice.
|date=2019
|date=10.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31744885
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956532
}}
}}
* {{medline-title
* {{medline-title
|title=Enhanced expression of PD-1 and other activation markers by CD4  T cells of young but not old patients with metastatic melanoma.
|title=Restoring extracellular matrix synthesis in senescent stem cells.
|date=06.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546435
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951899
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766659
}}
}}
* {{medline-title
* {{medline-title
|title=Non-linear patterns in age-related DNA methylation may reflect [[CD4]] T cell differentiation.
|title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells.
|date=03.06.2017
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28387568
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501198
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023
}}
}}
* {{medline-title
* {{medline-title
|title=Novel Senescent Regulatory T-Cell Subset with Impaired Suppressive Function in Rheumatoid Arthritis.
|title=Histopathological and molecular analysis of idiopathic pulmonary fibrosis lungs from patients treated with pirfenidone or nintedanib.
|date=2017
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28373873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30152895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357868
|full-text-url=https://sci-hub.do/10.1111/his.13745
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in CD4 CD25 [[FOXP3]] regulatory T cells and their relationship with lung cancer.
|title=Beta-Catenin and [[SMAD3]] Are Associated with Skeletal Muscle Aging in the Taurine Transpoeter Knockout Mouse.
|date=2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28253320
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849477
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333862
|full-text-url=https://sci-hub.do/10.1007/978-94-024-1079-2_39
}}
}}
==SNCA==
* {{medline-title
* {{medline-title
|title=Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects.
|title=Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease.
|date=10.2016
|date=22.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27190305
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31758049
|full-text-url=https://sci-hub.do/10.1189/jlb.5A0116-025R
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874660
}}
}}
==GAP43==
* {{medline-title
* {{medline-title
|title=HDAC inhibition leads to age-dependent opposite regenerative effect upon PTEN deletion in rubrospinal axons after SCI.
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading.
|date=06.2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32171589
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.02.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869
}}
}}
* {{medline-title
* {{medline-title
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=02.2019
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
* {{medline-title
* {{medline-title
|title=Differential expression of synaptic and interneuron genes in the aging human prefrontal cortex.
|title=Age-dependent accumulation of oligomeric [[SNCA]]/α-synuclein from impaired degradation in mutant [[LRRK2]] knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
|date=10.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031232
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983487
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.06.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984454
}}
}}
* {{medline-title
* {{medline-title
|title=Schwann Cell Phenotype Changes in Aging Human Dental Pulp.
|title=Caloric restriction rescues yeast cells from alpha-synuclein toxicity through autophagic control of proteostasis.
|date=03.2018
|date=07.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28972819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530923
|full-text-url=https://sci-hub.do/10.1177/0022034517733967
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326672
}}
}}
==SON==
* {{medline-title
* {{medline-title
|title=Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.
|title=Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha.
|date=01.01.2017
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28013231
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30861131
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656591
}}
}}
* {{medline-title
* {{medline-title
|title=Alterations of Ca²⁺-responsive proteins within cholinergic neurons in aging and Alzheimer's disease.
|title=Neural Mechanisms Involved in the Noxious Physical Stress-Induced Inhibition of Ovarian Estradiol Secretion.
|date=06.2014
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24461366
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30730610
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961506
|full-text-url=https://sci-hub.do/10.1002/ar.24078
}}
}}
==HBP1==
* {{medline-title
* {{medline-title
|title=Suppression of p38/[[HBP1]] pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence.
|title=Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats.
|date=03-04.2020
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32549582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518407
|full-text-url=https://sci-hub.do/10.23812/20-63-A-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019141
}}
}}
* {{medline-title
* {{medline-title
|title=Transcription factor [[HBP1]]: A regulator of senescence and apoptosis of preadipocytes.
|title=The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system.
|date=17.09.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331641
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29494864
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.07.048
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878011
}}
}}
* {{medline-title
* {{medline-title
|title=A positive feedback loop between Pim-1 kinase and [[HBP1]] transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis.
|title=Increased oxytocin-monomeric red fluorescent protein 1 fluorescent intensity with urocortin-like immunoreactivity in the hypothalamo-neurohypophysial system of aged transgenic rats.
|date=19.05.2017
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28348080
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28859972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437229
|full-text-url=https://sci-hub.do/10.1016/j.neures.2017.08.001
}}
}}
==SRF==
* {{medline-title
* {{medline-title
|title=Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve.
|title=Changes in snail and [[SRF]] expression in the kidneys of diabetic rats during ageing.
|date=10.2016
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27206316
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31668740
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041189
|full-text-url=https://sci-hub.do/10.1016/j.acthis.2019.151460
}}
}}
* {{medline-title
* {{medline-title
|title=[[HBP1]]-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/[[EZH2]] Pathways and Its Impact on Cell Senescence and Tumorigenesis.
|title=Mechanosensitive transcriptional coactivators MRTF-A and YAP/TAZ regulate nucleus pulposus cell phenotype through cell shape.
|date=10.06.2016
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27129219
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31638828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933444
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894097
}}
}}
* {{medline-title
* {{medline-title
|title=Absence of AMPKα2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts.
|title=Resource recovery potentials by landfill mining and reclamation in South Korea.
|date=02.2016
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26718972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31035180
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720555
|full-text-url=https://sci-hub.do/10.1016/j.jenvman.2019.01.101
}}
}}
==HCN1==
* {{medline-title
* {{medline-title
|title=Protein expression changes of [[HCN1]] and HCN2 in hippocampal subregions of gerbils during the normal aging process.
|title=Pre-existing fibroblasts of epicardial origin are the primary source of pathological fibrosis in cardiac ischemia and aging.
|date=11.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32128096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30771308
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585455
}}
}}
* {{medline-title
* {{medline-title
|title=HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation.
|title=Targeting MRTF/[[SRF]] in [[CAP2]]-dependent dilated cardiomyopathy delays disease onset.
|date=15.02.2019
|date=21.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30124776
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30762586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483011
}}
}}
==TAZ==
* {{medline-title
* {{medline-title
|title=Dopaminergic Neurons Exhibit an Age-Dependent Decline in Electrophysiological Parameters in the MitoPark Mouse Model of Parkinson's Disease.
|title=Transcriptional Coactivator [[TAZ]] Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence.
|date=06.04.2016
|date=09.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27053209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31936650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821912
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016652
}}
}}
* {{medline-title
* {{medline-title
|title=Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes.
|title=Downregulation of miR-125b promotes resistance of glioma cells to TRAIL through overexpression of Tafazzin which is a mitochondrial protein.
|date=11.11.2015
|date=05.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056533
|full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000455
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535077
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated expression of HCN channel isoforms in rat sinoatrial node.
|title=Dysregulation of the Hippo pathway signaling in aging and cancer.
|date=02.2016
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341471
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30910741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935443
|full-text-url=https://sci-hub.do/10.1016/j.phrs.2019.03.018
}}
}}
* {{medline-title
* {{medline-title
|title=Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse.
|title=Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging.
|date=27.02.2015
|date=03.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761792
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352274
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264619
}}
}}
==IL4==
* {{medline-title
* {{medline-title
|title=Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia.
|title=[[PGC]]-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing [[TAZ]].
|date=01.01.2018
|date=02.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122767
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30017591
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756472
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322535
}}
}}
==TRPM2==
* {{medline-title
* {{medline-title
|title=Aging Affects Bone Marrow Macrophage Polarization: Relevance to Bone Healing.
|title=Paraquat as an Environmental Risk Factor in Parkinson's Disease Accelerates Age-Related Degeneration Via Rapid Influx of Extracellular Zn  into Nigral Dopaminergic Neurons.
|date=06.2016
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28138512
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31119555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270653
|full-text-url=https://sci-hub.do/10.1007/s12035-019-01642-5
}}
}}
* {{medline-title
* {{medline-title
|title=[[IL4]]/[[STAT6]] Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain.
|title=Pathophysiological Role of [[TRPM2]] in Age-Related Cognitive Impairment in Mice.
|date=18.10.2016
|date=01.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27760324
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30999030
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2016.09.075
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2019.04.012
}}
}}
* {{medline-title
* {{medline-title
|title=[[IL10]]-driven [[STAT3]] signalling in senescent macrophages promotes pathological eye angiogenesis.
|title=The [[TRPM2]] channel nexus from oxidative damage to Alzheimer's pathologies: An emerging novel intervention target for age-related dementia.
|date=11.08.2015
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26260587
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30009973
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918330
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.002
}}
}}
* {{medline-title
* {{medline-title
|title=LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING.
|title=[[TRPM2]] in the Brain: Role in Health and Disease.
|date=06.2015
|date=22.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26087730
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037128
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070997
}}
}}
* {{medline-title
* {{medline-title
|title=Ageing related periostin expression increase from cardiac fibroblasts promotes cardiomyocytes senescent.
|title=mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development.
|date=26.09.2014
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25173938
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29842890
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.08.109
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.05.008
}}
}}
==ILK==
==TTR==


* {{medline-title
* {{medline-title
|title=Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy.
|title=Cellular secretion and cytotoxicity of transthyretin mutant proteins underlie late-onset amyloidosis and neurodegeneration.
|date=01.04.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30605403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31728576
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485685
|full-text-url=https://sci-hub.do/10.1007/s00018-019-03357-1
}}
}}
* {{medline-title
* {{medline-title
|title=Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia.
|title=Development of transgenic Caenorhabditis elegans expressing human transthyretin as a model for drug screening.
|date=10.2018
|date=14.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30271655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30552363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147593
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294829
}}
* {{medline-title
|title=Age-dependent cognitive dysfunction in untreated hereditary transthyretin amyloidosis.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209781
|full-text-url=https://sci-hub.do/10.1007/s00415-017-8668-8
}}
}}
* {{medline-title
* {{medline-title
|title=Integrin-linked kinase: A new actor in the ageing process?
|title=The delaying effect of alpha-glycerophosphocholine on senescence, transthyretin deposition, and osteoarthritis in senescence-accelerated mouse prone 8 mice.
|date=15.12.2017
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29191088
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.10.026
|full-text-url=https://sci-hub.do/10.1080/09168451.2017.1403883
}}
}}
* {{medline-title
* {{medline-title
|title=Hyperphosphatemia induces cellular senescence in human aorta smooth muscle cells through integrin linked kinase ([[ILK]]) up-regulation.
|title=Transthyretin deposition promotes progression of osteoarthritis.
|date=12.2015
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26467393
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28941045
|full-text-url=https://sci-hub.do/10.1016/j.mad.2015.10.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676063
}}
}}
==ZMPSTE24==
* {{medline-title
* {{medline-title
|title=Integrin-linked kinase regulates senescence in an Rb-dependent manner in cancer cell lines.
|title=Bone marrow-derived mesenchymal stem cells in three-dimensional co-culture attenuate degeneration of nucleus pulposus cells.
|date=2015
|date=30.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26176204
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31666429
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825635
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834418
}}
}}
* {{medline-title
* {{medline-title
|title=A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging.
|title=A humanized yeast system to analyze cleavage of prelamin A by [[ZMPSTE24]].
|date=06.2014
|date=15.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24400780
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30625386
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032615
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401292
}}
}}
==KEAP1==
* {{medline-title
* {{medline-title
|title=NRF2 pathway activation by [[KEAP1]] inhibition attenuates the manifestation of aging phenotypes in salivary glands.
|title=Proteomic Evidence of Biological Aging in a Child with a Compound Heterozygous [[ZMPSTE24]] Mutation.
|date=09.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32590331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492098
}}
}}
* {{medline-title
* {{medline-title
|title=Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds.
|title=Abnormal nuclear morphology is independent of longevity in a zmpste24-deficient fish model of Hutchinson-Gilford progeria syndrome (HGPS).
|date=18.05.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424161
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567411
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234996
|full-text-url=https://sci-hub.do/10.1016/j.cbpc.2018.03.006
}}
}}
* {{medline-title
* {{medline-title
|title=Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression.
|title=Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing.
|date=2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182922
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29208544
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535784
|full-text-url=https://sci-hub.do/10.1016/j.arr.2017.12.001
}}
}}
==ADA==
* {{medline-title
* {{medline-title
|title=Systemic overexpression of [[SQSTM1]]/p62 accelerates disease onset in a [[SOD1]] -expressing ALS mouse model.
|title=Adenosine Metabolism in the Cerebral Cortex from Several Mice Models during Aging.
|date=29.05.2018
|date=02.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843805
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33023260
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582336
}}
}}
* {{medline-title
* {{medline-title
|title=Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates.
|title=Risk factors for diabetic kidney disease in adults with longstanding type 1 diabetes: results from the Canadian Study of Longevity in Diabetes.
|date=04.2018
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31162987
|full-text-url=https://sci-hub.do/10.1111/nyas.13556
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566893
}}
}}
* {{medline-title
* {{medline-title
|title=The Anti-Aging Effect of Erythropoietin via the ERK/Nrf2-ARE Pathway in Aging Rats.
|title=Ideglira is Associated With Improved Short-Term Clinical Outcomes and Cost Savings Compared with Insulin Glargine U100 Plus Insulin Aspart in the U.S.
|date=03.2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28168414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30308134
|full-text-url=https://sci-hub.do/10.1007/s12031-017-0885-1
|full-text-url=https://sci-hub.do/10.4158/EP-2018-0134
}}
}}
==MAPK1==
* {{medline-title
* {{medline-title
|title=Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1.
|title=Mismatch between [[ADA]] and AGS recommendations for glycated hemoglobin targets for older adults.
|date=2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850814
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29396204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413062
|full-text-url=https://sci-hub.do/10.1016/j.pcd.2018.01.003
}}
}}
==AHR==
* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Indoles from the commensal microbiota act via the [[AHR]] and IL-10 to tune the cellular composition of the colonic epithelium during aging.
|date=15.04.2019
|date=01.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32817517
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474656
}}
}}
* {{medline-title
* {{medline-title
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|title=Role of the Aryl Hydrocarbon Receptor in Environmentally Induced Skin Aging and Skin Carcinogenesis.
|date=2018
|date=28.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31795255
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928879
}}
}}
* {{medline-title
* {{medline-title
|title=iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation.
|title=Loss of Neurogenesis in Aging Hydra.
|date=01.10.2017
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708522
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912256
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.06.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586502
}}
}}
* {{medline-title
* {{medline-title
|title=Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging.
|title=Environmental cues received during development shape dendritic cell responses later in life.
|date=01.07.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28515230
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30412605
|full-text-url=https://sci-hub.do/10.1242/jcs.197327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226176
}}
}}
* {{medline-title
==BPIFB4==
|title=Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25592202
|full-text-url=https://sci-hub.do/10.1159/000368305
}}
==MCU==


* {{medline-title
* {{medline-title
|title=A rare case of Epstein-Barr virus-positive mucocutaneous ulcer that developed into an intestinal obstruction: a case report.
|title=New Insights for [[BPIFB4]] in Cardiovascular Therapy.
|date=13.01.2020
|date=28.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31931725
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32998388
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958744
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583974
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of Mitochondrial Calcium Overload by SIRT3 Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue.
|title=LAV-[[BPIFB4]] associates with reduced frailty in humans and its transfer prevents frailty progression in old mice.
|date=02.2020
|date=28.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31712319
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31461407
|full-text-url=https://sci-hub.do/10.2337/db19-0526
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738439
}}
}}
* {{medline-title
* {{medline-title
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|title=Longevity-Associated Variant of [[BPIFB4]] Mitigates Monocyte-Mediated Acquired Immune Response.
|date=09.2019
|date=13.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074771
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
|full-text-url=https://sci-hub.do/10.1093/gerona/glz036
}}
}}
* {{medline-title
* {{medline-title
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling.
|title=A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of [[BPIFB4]].
|date=12.2018
|date=19.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30347645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214030
}}
}}
* {{medline-title
==C6==
|title=Physical exercise in aging human skeletal muscle increases mitochondrial calcium uniporter expression levels and affects mitochondria dynamics.
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210373
}}
* {{medline-title
|title=Evolution of increased adult longevity in Drosophila melanogaster populations selected for adaptation to larval crowding.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26575793
|full-text-url=https://sci-hub.do/10.1111/jeb.12795
}}
==MEF2C==


* {{medline-title
* {{medline-title
|title=Decline in cellular function of aged mouse c-kit  cardiac progenitor cells.
|title=Evolution of the Aroma of Treixadura Wines during Bottle Aging.
|date=01.10.2017
|date=08.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28737214
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33049919
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621489
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600726
}}
}}
* {{medline-title
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|title=D-galactose induces senescence of glioblastoma cells through YAP-CDK6 pathway.
|date=11.04.2017
|date=29.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32991321
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585072
}}
}}
* {{medline-title
* {{medline-title
|title=Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study.
|title=Alcohol Extracts From [i]Ganoderma lucidum[/i] Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents.
|date=01.12.2016
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27616567
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971923
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837042
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444160
}}
}}
* {{medline-title
* {{medline-title
|title=Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy.
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.
|date=03.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27612437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158
|full-text-url=https://sci-hub.do/10.1002/stem.2495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829
}}
}}
==CD33==
* {{medline-title
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|title=Maximum reproductive lifespan correlates with [[CD33]]rSIGLEC gene number: Implications for NADPH oxidase-derived reactive oxygen species in aging.
|date=04.2016
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31907986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018541
}}
}}
* {{medline-title
* {{medline-title
|title=Postnatal expression patterns and polymorphism analysis of the bovine myocyte enhancer factor 2C (Mef2C) gene.
|title=New genetic players in late-onset Alzheimer's disease: Findings of genome-wide association studies.
|date=12.2014
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25108515
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30381536
|full-text-url=https://sci-hub.do/10.1016/j.meatsci.2014.06.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206761
}}
}}
==MRE11==
* {{medline-title
* {{medline-title
|title=Chromosomal alterations among age-related haematopoietic clones in Japan.
|title=Chromogenic Multiplex Immunohistochemistry Reveals Modulation of the Immune Microenvironment Associated with Survival in Elderly Patients with Lung Adenocarcinoma.
|date=08.2020
|date=13.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32581364
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489641
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162494
}}
}}
* {{medline-title
* {{medline-title
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=2019
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
==CRH==
* {{medline-title
* {{medline-title
|title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment.
|title=Roles of peptides and steroids in sleep disorders.
|date=2018
|date=09.2006
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30754093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527
|full-text-url=https://sci-hub.do/10.1586/17446651.1.5.609
}}
}}
* {{medline-title
* {{medline-title
|title=Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=01.09.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775409
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172637
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
* {{medline-title
* {{medline-title
|title=BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries.
|title=Caenorhabditis elegans respond to high-glucose diets through a network of stress-responsive transcription factors.
|date=03.04.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552356
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990370
|full-text-url=https://sci-hub.do/10.1080/10495398.2016.1210613
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039004
}}
}}
* {{medline-title
* {{medline-title
|title=NBS1 is required for macrophage homeostasis and functional activity in mice.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=26.11.2015
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26324700
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://sci-hub.do/10.1182/blood-2015-04-637371
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==NES==
==CXCL8==


* {{medline-title
* {{medline-title
|title=Mini-review: Aging of the neuroendocrine system: Insights from nonhuman primate models.
|title=Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease.
|date=08.06.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31891735
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33041998
|full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2019.109854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525127
}}
}}
* {{medline-title
* {{medline-title
|title=Age Dependent Hypothalamic and Pituitary Responses to Novel Environment Stress or Lipopolysaccharide in Rats.
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615881
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
}}
}}
* {{medline-title
* {{medline-title
|title=[Prediction of life expectancy for prostate cancer patients based on the kinetic theory of aging of living systems].
|title=Immune senescence and biomarkers profile of Bambuí aged population-based cohort.
|date=2017
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849878
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29247791
 
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.12.006
}}
}}
* {{medline-title
* {{medline-title
|title=Self-reported Calcium Supplementation and Age-Related Macular Degeneration.
|title=Predictive value of multiple cytokines and chemokines for mortality in an admixed population: 15-year follow-up of the Bambui-Epigen (Brazil) cohort study of aging.
|date=07.2015
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25856252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803133
|full-text-url=https://sci-hub.do/10.1001/jamaophthalmol.2015.0514
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.002
}}
}}
==CXCR3==
* {{medline-title
* {{medline-title
|title=Association between phosphorus intake and bone health in the NHA[[NES]] population.
|title=Senescent hepatocytes enhance natural killer cell activity via the CXCL-10/[[CXCR3]] axis.
|date=21.03.2015
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25856461
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31616512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781833
}}
}}
* {{medline-title
* {{medline-title
|title=Human induced pluripotent stem cells improve recovery in stroke-injured aged rats.
|title=Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells.
|date=2014
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24916776
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696983
|full-text-url=https://sci-hub.do/10.3233/RNN-140404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474
}}
}}
==NOS1==
* {{medline-title
* {{medline-title
|title=Prepubertal overexposure to manganese induce precocious puberty through GABA receptor/nitric oxide pathway in immature female rats.
|title=[[CXCR3]] CD8  T cells with naïve phenotype and high capacity for IFN-γ production are generated during homeostatic T-cell proliferation.
|date=30.01.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31711775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30058200
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2019.109898
|full-text-url=https://sci-hub.do/10.1002/eji.201747431
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity.
|title=The parasite-derived rOv-ASP-1 is an effective antigen-sparing [[CD4]]  T cell-dependent adjuvant for the trivalent inactivated influenza vaccine, and functions in the absence of MyD88 pathway.
|date=10.2019
|date=14.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29764680
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595497
}}
}}
==CYP2C19==
* {{medline-title
* {{medline-title
|title=[[NOS3]] Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels.
|title=Physiologically Based Pharmacokinetic Approach Can Successfully Predict Pharmacokinetics of Citalopram in Different Patient Populations.
|date=11.07.2018
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891729
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31750550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041791
|full-text-url=https://sci-hub.do/10.1002/jcph.1541
}}
}}
* {{medline-title
* {{medline-title
|title=[[NOS1]] and [[SNAP25]] polymorphisms are associated with Attention-Deficit/Hyperactivity Disorder symptoms in adults but not in children.
|title=Longitudinal exposure of English primary care patients to pharmacogenomic drugs: An analysis to inform design of pre-emptive pharmacogenomic testing.
|date=04.2016
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26821215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31454087
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2016.01.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955399
}}
}}
* {{medline-title
* {{medline-title
|title=[[NOS1]] induces NADPH oxidases and impairs contraction kinetics in aged murine ventricular myocytes.
|title=The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers.
|date=09.2015
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26173391
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567399
|full-text-url=https://sci-hub.do/10.1007/s00395-015-0506-5
|full-text-url=https://sci-hub.do/10.1016/j.euroneuro.2018.01.003
}}
}}
* {{medline-title
* {{medline-title
|title=Sex-dependent hypertension and renal changes in aged rats with altered renal development.
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
|date=15.08.2014
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24944267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00198.2014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442
}}
}}
==NOS2==
==CYP2E1==


* {{medline-title
* {{medline-title
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity.
|title=DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver.
|date=10.2019
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32221779
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287002
}}
}}
* {{medline-title
* {{medline-title
|title=Secreted α-Klotho maintains cartilage tissue homeostasis by repressing [i][[NOS2]][/i] and [i]ZIP8-MMP13[/i] catabolic axis.
|title=2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms.
|date=19.06.2018
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29920476
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30939745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046234
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479705
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging.
|title=Neuroprotective Effect of Dioscin on the Aging Brain.
|date=28.12.2016
|date=30.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30935017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479446
}}
}}
* {{medline-title
* {{medline-title
|title=All-trans retinoic acid (ATRA) prevents lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment in aged rats.
|title=Cytochrome P450-2E1 is involved in aging-related kidney damage in mice through increased nitroxidative stress.
|date=15.11.2016
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27806872
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28843596
|full-text-url=https://sci-hub.do/10.1016/j.jneuroim.2016.10.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656532
}}
}}
==DCC==
* {{medline-title
* {{medline-title
|title=TNFα antagonization alters [[NOS2]] dependent nasopharyngeal carcinoma tumor growth.
|title=X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation.
|date=07.2015
|date=21.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25912222
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31495695
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2015.04.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810858
}}
}}
* {{medline-title
* {{medline-title
|title=Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli.
|title=Dynamic functional connectivity analysis of functional MRI based on copula time-varying correlation.
|date=09.04.2015
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25890218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31100293
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397943
|full-text-url=https://sci-hub.do/10.1016/j.jneumeth.2019.05.004
}}
}}
==NOTCH1==
* {{medline-title
* {{medline-title
|title=[How Does Aging Contribute to Cancer?]
|title=Comprehensive outpatient rehabilitation increases the ability of people over 60 to live independently.
|date=09.2020
|date=20.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33130684
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30586960
 
|full-text-url=https://sci-hub.do/10.26444/aaem/99642
}}
}}
* {{medline-title
* {{medline-title
|title=H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice.
|title=Mesocorticolimbic Connectivity and Volumetric Alterations in [i][[DCC]][/i] Mutation Carriers.
|date=10.2019
|date=16.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31609547
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29712788
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778597
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956985
}}
}}
==EFS==
* {{medline-title
* {{medline-title
|title=Age-related remodelling of oesophageal epithelia by mutated cancer drivers.
|title=The aging bladder phenotype is not the direct consequence of bladder aging.
|date=01.2019
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30602793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31452236
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0811-x
|full-text-url=https://sci-hub.do/10.1002/nau.24149
}}
}}
* {{medline-title
* {{medline-title
|title=Dynamic regulation of [[NOTCH1]] activation and Notch ligand expression in human thymus development.
|title=Autonomic dysregulation at multiple sites is implicated in age-associated underactive bladder in female mice.
|date=13.08.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30042180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30932250
|full-text-url=https://sci-hub.do/10.1242/dev.165597
|full-text-url=https://sci-hub.do/10.1002/nau.23990
}}
}}
* {{medline-title
* {{medline-title
|title=Long telomeres protect against age-dependent cardiac disease caused by [[NOTCH1]] haploinsufficiency.
|title=Does the empty follicle syndrome occur in cases of low number of maturing follicles in assisted reproduction?
|date=01.05.2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28346225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30303699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409071
|full-text-url=https://sci-hub.do/10.1080/09513590.2018.1519793
}}
}}
* {{medline-title
* {{medline-title
|title=Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study.
|title=Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats.
|date=09.04.2016
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27060904
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705109
}}
}}
==PDE4C==
==ERAS==


* {{medline-title
* {{medline-title
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|title=Enhanced Recovery After Surgery: Are the Principles Applicable to Adult and Geriatric Acute Care and Trauma Surgery?
|date=04.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30711234
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
|full-text-url=https://sci-hub.do/10.1016/j.anclin.2018.10.001
}}
}}
* {{medline-title
* {{medline-title
|title=Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system.
|title=Prospective application of an implementation framework to improve postoperative nutrition care processes: Evaluation of a mixed methods implementation study.
|date=09.2016
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27337627
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30151938
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2016.06.005
|full-text-url=https://sci-hub.do/10.1111/1747-0080.12464
}}
}}
* {{medline-title
* {{medline-title
|title=Plasma Amyloid Beta 1-42 and DNA Methylation Pattern Predict Accelerated Aging in Young Subjects with Down Syndrome.
|title=Enhanced Recovery After Surgery ([[ERAS]]) - The Evidence in Geriatric Emergency Surgery: A Systematic Review.
|date=12.2016
|date=Sept-10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27234618
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088554
|full-text-url=https://sci-hub.do/10.1007/s12017-016-8413-y
|full-text-url=https://sci-hub.do/10.21614/chirurgia.112.5.546
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model.
|title=Multimodal Rehabilitation in Geriatric Emergency Surgery.
|date=03.2016
|date=Sept-10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26861500
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798846
|full-text-url=https://sci-hub.do/10.21614/chirurgia.112.5.558
}}
}}
==FGA==
* {{medline-title
* {{medline-title
|title=Improved age determination of blood and teeth samples using a selected set of DNA methylation markers.
|title=Goal Pursuit, Goal Adjustment, and Pain in Middle-Aged Adults Aging With Physical Disability.
|date=2015
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26280308
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31718416
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844214
|full-text-url=https://sci-hub.do/10.1177/0898264319827142
}}
}}
* {{medline-title
* {{medline-title
|title=Aging of blood can be tracked by DNA methylation changes at just three CpG sites.
|title=Tenacious Goal Pursuit, Flexible Goal Adjustment, and Life Satisfaction Among Chinese Older Adult Couples.
|date=03.02.2014
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24490752
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31547780
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053864
|full-text-url=https://sci-hub.do/10.1177/0164027519876125
}}
}}
==PGP==
* {{medline-title
* {{medline-title
|title=Age-associated changes of the intrinsic nervous system in relation with interstitial cells in the pre-weaning goat rumen.
|title=Association of tenacious goal pursuit and flexible goal adjustment with out-of-home mobility among community-dwelling older people.
|date=14.07.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31305258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30449015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660047
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682663
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats.
|title=Assimilative and accommodative coping in older adults with and without sensory impairment: four-year change and prospective relations with affective well-being.
|date=2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182640
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30407084
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705109
|full-text-url=https://sci-hub.do/10.1080/13607863.2018.1479833
}}
}}
==FGF19==
* {{medline-title
* {{medline-title
|title=Change in the Interstitial Cells of Cajal and nNOS Positive Neuronal Cells with Aging in the Stomach of F344 Rats.
|title=Bile acid receptor agonists in primary biliary cholangitis: Regulation of the cholangiocyte secretome and downstream T cell differentiation.
|date=2017
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28045993
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32123836
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207530
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996327
}}
}}
* {{medline-title
* {{medline-title
|title=The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via [[CXCR1]]-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs.
|title=Kotho and aging.
|date=01.2017
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27769935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557478
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2016.10.011
 
}}
}}
* {{medline-title
* {{medline-title
|title=[CHANGES IN [[TH]]E PANCREATIC ISLETS AND NERVOUS ELEMENTS IN RATS DURING AGING (AN IMMUNOHISTOCHEMICAL STUDY)].
|title=The Klotho proteins in health and disease.
|date=2015
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27141588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427
 
|full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3
}}
}}
* {{medline-title
* {{medline-title
|title=Associations between xerostomia, histopathological alterations, and autonomic innervation of labial salivary glands in men in late midlife.
|title=Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging.
|date=09.2014
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24905142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765501
|full-text-url=https://sci-hub.do/10.1016/j.exger.2014.06.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889864
}}
}}
==PIK3CA==
==FGF2==


* {{medline-title
* {{medline-title
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|title=The influence of fibroblast growth factor 2 on the senescence of human adipose-derived mesenchymal stem cells during long-term culture.
|date=10.06.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31840944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103622
}}
}}
* {{medline-title
* {{medline-title
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|title=Adipose-Derived Stem/Stromal Cells Recapitulate Aging Biomarkers and Show Reduced Stem Cell Plasticity Affecting Their Adipogenic Differentiation Capacity.
|date=10.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31298565
|full-text-url=https://sci-hub.do/10.1002/path.5314
|full-text-url=https://sci-hub.do/10.1089/cell.2019.0010
}}
}}
* {{medline-title
* {{medline-title
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient.
|title=Evaluation of human mesenchymal stem cell senescence, differentiation and secretion behavior cultured on polycarbonate cell culture inserts.
|date=09.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30372670
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7
|full-text-url=https://sci-hub.do/10.3233/CH-189322
}}
}}
* {{medline-title
* {{medline-title
|title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]] accompanied with pro-tumorigenic secretome.
|title=Young bone marrow Sca-1 cells protect aged retina from ischaemia-reperfusion injury through activation of [[FGF2]].
|date=01.08.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30255622
|full-text-url=https://sci-hub.do/10.1002/ijc.32153
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237572
}}
}}
==FGR==
* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Aurora kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction.
|date=02.2019
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32452402
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://sci-hub.do/10.1016/j.placenta.2020.04.012
}}
}}
* {{medline-title
* {{medline-title
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|title=Premature Vascular Aging in Guinea Pigs Affected by Fetal Growth Restriction.
|date=2015
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31311132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678381
}}
}}
==PON1==
* {{medline-title
* {{medline-title
|title=Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview.
|title=Premature placental aging in term small-for-gestational-age and growth-restricted fetuses.
|date=02.05.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31052559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125412
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562914
|full-text-url=https://sci-hub.do/10.1002/uog.20103
}}
}}
* {{medline-title
* {{medline-title
|title=The role of paraoxonase 1 in regulating high-density lipoprotein functionality during aging.
|title=The effect of fertility treatment on adverse perinatal outcomes in women aged at least 40 years.
|date=10.2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28746818
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994115
|full-text-url=https://sci-hub.do/10.1139/cjpp-2017-0117
|full-text-url=https://sci-hub.do/10.1002/ijgo.12345
}}
}}
==FOXM1==
* {{medline-title
* {{medline-title
|title=Advanced glycation end products affect cholesterol homeostasis by impairing [[ABCA1]] expression on macrophages.
|title=Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression.
|date=08.2017
|date=10.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28704619
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33171439
|full-text-url=https://sci-hub.do/10.1139/cjpp-2017-0170
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695388
}}
}}
* {{medline-title
* {{medline-title
|title=Paraoxonase-1 ([[PON1]]) rs662 Polymorphism and Its Association with Serum Lipid Levels and Longevity in the Bama Zhuang Population.
|title=Upregulation of [[FOXM1]] leads to diminished drug sensitivity in myeloma.
|date=27.12.2016
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28027289
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463534
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214702
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249818
}}
}}
* {{medline-title
* {{medline-title
|title=Differential effects of a high-fat diet on serum lipid parameters and ovarian gene expression in young and aged female mice.
|title=Preclinical characterization of abemaciclib in hormone receptor positive breast cancer.
|date=10.2016
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26883034
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29050219
|full-text-url=https://sci-hub.do/10.1017/S0967199415000684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642494
}}
}}
* {{medline-title
* {{medline-title
|title=Paraoxonase ([[PON1]]) polymorphisms Q192R and L55M are not associated with human longevity: A meta-analysis.
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
|date=01.2016
|date=02.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25962362
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919
|full-text-url=https://sci-hub.do/10.1007/s00391-015-0892-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654
}}
}}
==POR==
==FOXO6==


* {{medline-title
* {{medline-title
|title=The Ventricular System Enlarges Abnormally in the Seventies, Earlier in Men, and First in the Frontal Horn: A Study Based on More Than 3,000 Scans.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31749695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848156
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
* {{medline-title
* {{medline-title
|title=Clinical findings associated with development of postoperative reflux and short-term survival after small intestinal surgery in geriatric and mature nongeriatric horses.
|title=Introduction to FOXO Biology.
|date=07.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002397
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414140
|full-text-url=https://sci-hub.do/10.1111/vsu.13217
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-8900-3_1
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia.
|title=FOXO in Neural Cells and Diseases of the Nervous System.
|date=12.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433734
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881381
}}
}}
* {{medline-title
* {{medline-title
|title=Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis.
|title=FOXO Transcriptional Factors and Long-Term Living.
|date=01.05.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412544
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894507
|full-text-url=https://sci-hub.do/10.1016/j.molp.2017.03.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574317
}}
}}
==GAA==
* {{medline-title
* {{medline-title
|title=Endometriosis has no negative impact on outcomes of in vitro fertilisation in women with poor ovarian response.
|title=Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia.
|date=09.2016
|date=27.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27627604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32586831
|full-text-url=https://sci-hub.do/10.1111/1471-0528.14018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406325
}}
}}
* {{medline-title
* {{medline-title
|title=Short-term complications after colic surgery in geriatric versus mature non-geriatric horses.
|title=Age-Related Changes in Serum Guanidinoacetic Acid in Women.
|date=02.2015
|date=30.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25289944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31647299
|full-text-url=https://sci-hub.do/10.1111/j.1532-950X.2014.12281.x
|full-text-url=https://sci-hub.do/10.33549/physiolres.934189
}}
}}
==PPID==
* {{medline-title
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756


* {{medline-title
|title=Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32058159
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2020.110013
}}
}}
* {{medline-title
* {{medline-title
|title=Epidemiology of pituitary pars intermedia dysfunction: A systematic literature review of clinical presentation, disease prevalence and risk factors.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=05.2018
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29704935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://sci-hub.do/10.1016/j.tvjl.2018.03.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==GAP43==
* {{medline-title
* {{medline-title
|title=Effect of Age, Season, Body Condition, and Endocrine Status on Serum Free Cortisol Fraction and Insulin Concentration in Horses.
|title=HDAC inhibition leads to age-dependent opposite regenerative effect upon PTEN deletion in rubrospinal axons after SCI.
|date=03-04.2016
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26860336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32171589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913614
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.02.006
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related Qualitative Histological and Quantitative Stereological Changes in the Equine Pituitary.
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|date=02-04.2016
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26810844
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|full-text-url=https://sci-hub.do/10.1016/j.jcpa.2015.11.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
}}
}}
* {{medline-title
* {{medline-title
|title=What's New in Old Horses? Postmortem Diagnoses in Mature and Aged Equids.
|title=Differential expression of synaptic and interneuron genes in the aging human prefrontal cortex.
|date=03.2016
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26459516
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031232
|full-text-url=https://sci-hub.do/10.1177/0300985815608674
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.06.011
}}
}}
* {{medline-title
* {{medline-title
|title=Pituitary pars intermedia dysfunction does not necessarily impair insulin sensitivity in old horses.
|title=Schwann Cell Phenotype Changes in Aging Human Dental Pulp.
|date=01.2015
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25240230
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28972819
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2014.07.003
|full-text-url=https://sci-hub.do/10.1177/0022034517733967
}}
}}
==RAD50==
==GAPDH==


* {{medline-title
* {{medline-title
|title=Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells.
|title=Age-dependent accumulation of oligomeric [[SNCA]]/α-synuclein from impaired degradation in mutant [[LRRK2]] knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).
|date=01.09.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775409
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983487
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984454
}}
}}
* {{medline-title
* {{medline-title
|title=Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis.
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=01.05.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412544
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://sci-hub.do/10.1016/j.molp.2017.03.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
}}
* {{medline-title
* {{medline-title
|title=HIF-1α and rapamycin act as gerosuppressant in multiple myeloma cells upon genotoxic stress.
|title=Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves.
|date=17.08.2016
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27340936
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993538
|full-text-url=https://sci-hub.do/10.24425/119039
}}
}}
* {{medline-title
* {{medline-title
|title=Immunochip analysis identifies association of the [[RAD50]]/IL13 region with human longevity.
|title=Changes in contractile and metabolic parameters of skeletal muscle as rats age from 3 to 12 months.
|date=06.2016
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27004735
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29185184
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854908
|full-text-url=https://sci-hub.do/10.1007/s10974-017-9484-6
}}
}}
==GCLM==
* {{medline-title
* {{medline-title
|title=Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.
|title=Silencing Bach1 alters aging-related changes in the expression of Nrf2-regulated genes in primary human bronchial epithelial cells.
|date=29.09.2015
|date=15.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31422075
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598835
|full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108074
}}
}}
* {{medline-title
* {{medline-title
|title=Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells.
|title=Ontogeny and aging of Nrf2 pathway genes in livers of rats.
|date=06.2015
|date=15.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24747666
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29689272
|full-text-url=https://sci-hub.do/10.1093/gerona/glu019
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2018.04.018
}}
}}
==RIPK1==
* {{medline-title
 
|title=Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates.
* {{medline-title
|date=04.2018
|title=Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377163
|date=18.11.2020
|full-text-url=https://sci-hub.do/10.1111/nyas.13556
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33206046
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673785
}}
}}
* {{medline-title
* {{medline-title
|title=Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma.
|title=Aging-related decline in the induction of Nrf2-regulated antioxidant genes in human bronchial epithelial cells.
|date=05.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31981738
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28863281
|full-text-url=https://sci-hub.do/10.1016/j.joca.2020.01.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576992
}}
}}
==GGCT==
* {{medline-title
* {{medline-title
|title=RIP kinases as modulators of inflammation and immunity.
|title=Blockade of γ-Glutamylcyclotransferase Enhances Docetaxel Growth Inhibition of Prostate Cancer Cells.
|date=09.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31519583
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x
|full-text-url=https://sci-hub.do/10.21873/anticanres.13666
}}
}}
* {{medline-title
* {{medline-title
|title=[[TBK1]] Suppresses [[RIPK1]]-Driven Apoptosis and Inflammation during Development and in Aging.
|title=Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase ([[GGCT]]): A Novel Molecular Target for Anticancer Therapy.
|date=06.09.2018
|date=14.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30146158
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30011933
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128749
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073726
}}
}}
* {{medline-title
* {{medline-title
|title=Necroptosis increases with age and is reduced by dietary restriction.
|title=Depletion of gamma-glutamylcyclotransferase in cancer cells induces autophagy followed by cellular senescence.
|date=08.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696779
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29736310
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934555
}}
}}
* {{medline-title
* {{medline-title
|title=[[RIPK1]]-[[RIPK3]]-[[MLKL]]-dependent necrosis promotes the aging of mouse male reproductive system.
|title=Prohibitin-2 is a novel regulator of p21  induced by depletion of γ-glutamylcyclotransferase.
|date=15.08.2017
|date=29.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807105
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29307834
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557593
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.029
}}
}}
==RUNX1==
==GRK2==


* {{medline-title
* {{medline-title
|title=RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing [[RUNX1]] fusion oncoproteins.
|title=G protein-coupled receptor kinase 2 modifies the ability of Caenorhabditis elegans to survive oxidative stress.
|date=03.2018
|date=16.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29052866
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33064264
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813226
|full-text-url=https://sci-hub.do/10.1007/s12192-020-01168-z
}}
}}
* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=G protein coupled receptor kinases modulate Caenorhabditis elegans reactions to heat stresses.
|date=2017
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768194
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.07.121
}}
}}
* {{medline-title
* {{medline-title
|title=Conversion of adult endothelium to immunocompetent haematopoietic stem cells.
|title=Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging.
|date=25.05.2017
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28514438
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32216616
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794215
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346533
}}
}}
* {{medline-title
* {{medline-title
|title=Resistance Training Enhances Skeletal Muscle Innervation Without Modifying the Number of Satellite Cells or their Myofiber Association in Obese Older Adults.
|title=Senescent Cells Differentially Translate Senescence-Related mRNAs Via Ribosome Heterogeneity.
|date=10.2016
|date=18.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26447161
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30285098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018557
|full-text-url=https://sci-hub.do/10.1093/gerona/gly228
}}
}}
==HMGB2==
* {{medline-title
* {{medline-title
|title=Epigenetic Aging Signatures Are Coherently Modified in Cancer.
|title=Loss of Endogenous [[HMGB2]] Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice.
|date=06.2015
|date=25.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26110659
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30487376
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482318
|full-text-url=https://sci-hub.do/10.1253/circj.CJ-18-0925
}}
}}
* {{medline-title
* {{medline-title
|title=Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex.
|title=[[HMGB2]] Loss upon Senescence Entry Disrupts Genomic Organization and Induces [[CTCF]] Clustering across Cell Types.
|date=08.2015
|date=17.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26002684
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706538
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503803
|full-text-url=https://sci-hub.do/10.1016/j.molcel.2018.03.030
}}
}}
==SHH==
* {{medline-title
* {{medline-title
|title=Recent advances in [[SHH]] medulloblastoma progression: tumor suppressor mechanisms and the tumor microenvironment.
|title=Correlations between age, functional status, and the senescence-associated proteins [[HMGB2]] and p16 .
|date=2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31700613
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29651745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820827
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964056
}}
}}
* {{medline-title
* {{medline-title
|title=An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through [[SERPINB2]].
|title=Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence.
|date=03.07.2019
|date=30.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935093
}}
}}
==HMGCR==
* {{medline-title
* {{medline-title
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|title=Cholesterol Homeostasis: An In Silico Investigation into How Aging Disrupts Its Key Hepatic Regulatory Mechanisms.
|date=02.2019
|date=30.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33007859
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599957
}}
}}
* {{medline-title
* {{medline-title
|title=Evasion of cell senescence in [[SHH]] medulloblastoma.
|title=Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence.
|date=17.08.2016
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27229128
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31746143
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933330
}}
}}
* {{medline-title
* {{medline-title
|title=Expression and Role of Sonic Hedgehog in the Process of Fracture Healing with Aging.
|title=Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging.
|date=03-04.2016
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30609251
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413652
}}
}}
* {{medline-title
* {{medline-title
|title=The Subjective Health Horizon Questionnaire ([[SHH]]-Q): Assessing Future Time Perspectives for Facets of an Active Lifestyle.
|title=The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
|date=2016
|date=15.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26820307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125687
|full-text-url=https://sci-hub.do/10.1159/000441493
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.08.003
}}
}}
==SMAD2==
==IGFBP2==


* {{medline-title
* {{medline-title
|title=Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation.
|title=Intracellular Insulin-like growth factor binding protein 2 ([[IGFBP2]]) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21.
|date=02.2020
|date=17.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31674011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32302288
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202509
}}
}}
* {{medline-title
* {{medline-title
|title=Restoring extracellular matrix synthesis in senescent stem cells.
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|date=10.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287964
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766659
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
}}
}}
* {{medline-title
* {{medline-title
|title=iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation.
|title=IGFBP-2 and aging: a 20-year longitudinal study on IGFBP-2, IGF-I, BMI, insulin sensitivity and mortality in an aging population.
|date=01.10.2017
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708522
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30475224
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.06.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445262
}}
}}
* {{medline-title
* {{medline-title
|title=Exogenous [[GDF11]] induces cardiac and skeletal muscle dysfunction and wasting.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=07.2017
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28647906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833306
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==IL1B==
* {{medline-title
* {{medline-title
|title=Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.
|title=Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B.
|date=08.01.2016
|date=18.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26489925
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30998506
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748736
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542605
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of aging on cardiac extracellular matrix in men and women.
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|date=01.2016
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26280680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|full-text-url=https://sci-hub.do/10.1002/prca.201500031
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
}}
}}
==SOD3==
* {{medline-title
* {{medline-title
|title=Prenatal hypoxia affected endothelium-dependent vasodilation in mesenteric arteries of aged offspring via increased oxidative stress.
|title=Measuring the Inflammasome in Oncogene-Induced Senescence.
|date=06.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30617312
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30474840
|full-text-url=https://sci-hub.do/10.1038/s41440-018-0181-7
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-8931-7_7
}}
}}
* {{medline-title
* {{medline-title
|title=Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage.
|title=Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin.
|date=2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222787
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28777886
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721243
}}
}}
==IMPACT==
* {{medline-title
* {{medline-title
|title=In silico analysis and molecular dynamics simulation of human superoxide dismutase 3 ([[SOD3]]) genetic variants.
|title=Load-dependent modulation of alpha oscillations during working memory encoding and retention in young and older adults.
|date=03.2019
|date=03.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206983
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33141460
|full-text-url=https://sci-hub.do/10.1002/jcb.27636
|full-text-url=https://sci-hub.do/10.1111/psyp.13719
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Using Video Telehealth to Deliver Patient-Centered Collaborative Care: The G-[[IMPACT]] Pilot.
|date=02.2018
|date=31.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32228299
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://sci-hub.do/10.1080/07317115.2020.1738000
}}
}}
* {{medline-title
* {{medline-title
|title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa.
|title=AGING, HEART RATE VARIABILITY AND METABOLIC [[IMPACT]] OF OBESITY.
|date=2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31969754
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971797
}}
}}
* {{medline-title
* {{medline-title
|title=Extracellular superoxide dismutase deficiency impairs wound healing in advanced age by reducing neovascularization and fibroblast function.
|title=Endophytic Bacillus strains isolated from alfalfa (Medicago sativa L.) seeds: enhancing the lifespan of Caenorhabditis elegans.
|date=03.2016
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26663425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30489645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998179
|full-text-url=https://sci-hub.do/10.1111/lam.13102
}}
}}
==SSB==
==IRS2==


* {{medline-title
* {{medline-title
|title=Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study.
|title=Effects of Heshouwuyin on gene expression of the insulin/IGF signalling pathway in rat testis and spermatogenic cells.
|date=03.12.2019
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816850
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33264567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950484
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717869
}}
* {{medline-title
|title=Involvement of insulin receptor substrates in cognitive impairment and Alzheimer's disease.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30964050
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524492
}}
* {{medline-title
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
}}
}}
* {{medline-title
* {{medline-title
|title=WHIRLY1 Occupancy Affects Histone Lysine Modification and [i]WRKY53[/i] Transcription in [i]Arabidopsis[/i] Developmental Manner.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30405658
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202938
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
==JAK1==
* {{medline-title
* {{medline-title
|title=Modelled health benefits of a sugar-sweetened beverage tax across different socioeconomic groups in Australia: A cost-effectiveness and equity analysis.
|title=Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling.
|date=06.2017
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28654688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32233952
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486958
|full-text-url=https://sci-hub.do/10.1152/ajpcell.00520.2019
}}
}}
* {{medline-title
* {{medline-title
|title=Reduction of Sugar-Sweetened Beverage Consumption in Elementary School Students Using an Educational Curriculum of Beverage Sugar Content.
|title=The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Through [[JAK1]].
|date=2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28620628
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396213
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6665952
}}
}}
* {{medline-title
* {{medline-title
|title=Interannual and Spatial Variability in Maturity of Walleye Pollock Gadus chalcogrammus and Implications for Spawning Stock Biomass Estimates in the Gulf of Alaska.
|title=Influence of age and renal impairment on the steady state pharmacokinetics of filgotinib, a selective [[JAK1]] inhibitor.
|date=2016
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27736982
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256002
}}
}}
* {{medline-title
* {{medline-title
|title=Age dynamics of DNA damage and CpG methylation in the peripheral blood leukocytes of mice.
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|date=05.2015
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25867117
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|full-text-url=https://sci-hub.do/10.1016/j.mrfmmm.2015.03.006
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
}}
}}
==TIGIT==
==JUN==


* {{medline-title
* {{medline-title
|title=Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma.
|title=Age-Onset Phosphorylation of a Minor Actin Variant Promotes Intestinal Barrier Dysfunction.
|date=05.2019
|date=02.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30768970
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794717
|full-text-url=https://sci-hub.do/10.1016/j.jtho.2019.01.024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897307
}}
* {{medline-title
|title=1,3,5,8-Tetrahydroxy-9H-xanthen-9-one exerts its antiageing effect through the regulation of stress-response genes and the MAPK signaling pathway.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31313862
|full-text-url=https://sci-hub.do/10.1002/ardp.201900100
}}
}}
* {{medline-title
* {{medline-title
|title=Multivariate Computational Analysis of Gamma Delta T Cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV  Aging.
|title=Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration [i]in vivo[/i].
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30568654
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157327
}}
}}
* {{medline-title
* {{medline-title
|title=Characterization of Blimp-1 function in effector regulatory T cells.
|title=Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor [[JUN]].
|date=07.2018
|date=31.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29724515
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30012597
|full-text-url=https://sci-hub.do/10.1016/j.jaut.2018.04.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077742
}}
* {{medline-title
|title=T-cell Immunoglobulin and ITIM Domain Contributes to CD8  T-cell Immunosenescence.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29349889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847879
}}
* {{medline-title
|title=Long-Lived [[CD4]] IFN-γ  T Cells rather than Short-Lived [[CD4]] IFN-γ IL-10  T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection.
|date=15.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27630165
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055201
}}
}}
* {{medline-title
==KLF14==
|title=Combinatorial approach to cancer immunotherapy: strength in numbers.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27256570
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608090
}}
==TIMP1==


* {{medline-title
* {{medline-title
|title=Design, cyclization, and optimization of [[MMP13]]-[[TIMP1]] interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis.
|title=DNA methylation of the [[ELOVL2]], [[FHL2]], [[KLF14]], C1orf132/MIR29B2C, and [[TRIM59]] genes for age prediction from blood, saliva, and buccal swab samples.
|date=01.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352228
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30300865
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.10.141
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010
}}
}}
* {{medline-title
* {{medline-title
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|title=Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing.
|date=2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031222
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.07.007
}}
}}
* {{medline-title
* {{medline-title
|title=Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=04.2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866058
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2016.10.002
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of [[TIMP1]] transfection on [[PTEN]] expression in human kidney proximal tubular cells.
|title=Detection and evaluation of DNA methylation markers found at [[SCGN]] and [[KLF14]] loci to estimate human age.
|date=21.12.2015
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26782378
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854399
|full-text-url=https://sci-hub.do/10.4238/2015.December.21.6
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011
}}
}}
==LEP==
* {{medline-title
* {{medline-title
|title=Biological Effects Induced by Specific Advanced Glycation End Products in the Reconstructed Skin Model of Aging.
|title=Age- and Sex-Specific Changes in Lower-Limb Muscle Power Throughout the Lifespan.
|date=2015
|date=18.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26309782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31943003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497626
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa013
}}
}}
* {{medline-title
* {{medline-title
|title=Fat and Sucrose Intake Induces Obesity-Related Bone Metabolism Disturbances: Kinetic and Reversibility Studies in Growing and Adult Rats.
|title=The Copenhagen Sarcopenia Study: lean mass, strength, power, and physical function in a Danish cohort aged 20-93 years.
|date=01.2016
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26175082
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31419087
|full-text-url=https://sci-hub.do/10.1002/jbmr.2596
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903448
}}
}}
==TPO==
* {{medline-title
* {{medline-title
|title=Megakaryocytes promote osteoclastogenesis in aging.
|title=Caregiving for Older Adults with Limited English Proficiency: Transitioning from Hospital to Home.
|date=07.07.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31236893
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712121
}}
}}
* {{medline-title
* {{medline-title
|title=To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex-independent) NOD.H2  mice.
|title=Effects of macronutrient intake on the lifespan and fecundity of the marula fruit fly, [i]Ceratitis cosyra[/i] (Tephritidae): Extreme lifespan in a host specialist.
|date=04.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566234
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29188010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696426
}}
}}
==LTA==
* {{medline-title
* {{medline-title
|title=Kras is Required for Adult Hematopoiesis.
|title=Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice.
|date=07.2016
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26972179
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814084
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031475
}}
}}
* {{medline-title
* {{medline-title
|title=Signal for Thrombosis with Eltrombopag and Romiplostim: A Disproportionality Analysis of Spontaneous Reports Within VigiBase®.
|title=The change of pain classes over time: a latent transition analysis.
|date=12.2015
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26338346
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31680381
|full-text-url=https://sci-hub.do/10.1007/s40264-015-0337-1
|full-text-url=https://sci-hub.do/10.1002/ejp.1502
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of different photoinitiators and reducing agents on cure efficiency and color stability of resin-based composites using different LED wavelengths.
|title=Leisure time activities as mediating variables in functional disability progression: An application of parallel latent growth curve modeling.
|date=12.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26343422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30281590
|full-text-url=https://sci-hub.do/10.1016/j.jdent.2015.08.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169861
}}
}}
* {{medline-title
* {{medline-title
|title=Complex reference value distributions and partitioned reference intervals across the pediatric age range for 14 specialized biochemical markers in the CALIPER cohort of healthy community children and adolescents.
|title=The Neighborhood Built Environment and Cognitive Function of Older Persons: Results from the Singapore Longitudinal Ageing Study.
|date=23.10.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26310965
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28910813
|full-text-url=https://sci-hub.do/10.1016/j.cca.2015.08.020
|full-text-url=https://sci-hub.do/10.1159/000480080
}}
}}
==TPP1==
==MAG==


* {{medline-title
* {{medline-title
|title=FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping.
|title=Exploration of life satisfaction of Korean people with sensory impairments across the lifespan.
|date=03.11.2020
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33086033
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32327387
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2020.10.004
|full-text-url=https://sci-hub.do/10.1016/j.dhjo.2020.100931
}}
}}
* {{medline-title
* {{medline-title
|title=Gemfibrozil, food and drug administration-approved lipid-lowering drug, increases longevity in mouse model of late infantile neuronal ceroid lipofuscinosis.
|title=Omega-3 Monoacylglyceride Effects on Longevity, Mitochondrial Metabolism and Oxidative Stress: Insights from [i]Drosophila melanogaster[/i].
|date=05.2017
|date=16.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266923
}}
}}
* {{medline-title
* {{medline-title
|title=Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease.
|title=Glial Sulfatides and Neuronal Complex Gangliosides Are Functionally Interdependent in Maintaining Myelinating Axon Integrity.
|date=01.2017
|date=02.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27559927
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30446529
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248966
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325269
}}
}}
* {{medline-title
* {{medline-title
|title=Increased expression of telomere-regulating genes in endurance athletes with long leukocyte telomeres.
|title=Gray Matter Volume and Cognitive Performance During Normal Aging. A Voxel-Based Morphometry Study.
|date=15.01.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26586905
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30123123
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00587.2015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085481
}}
}}
==MCU==
* {{medline-title
* {{medline-title
|title=[[SIRT1]] ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin.
|title=A rare case of Epstein-Barr virus-positive mucocutaneous ulcer that developed into an intestinal obstruction: a case report.
|date=2014
|date=13.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24917814
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31931725
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958744
}}
}}
* {{medline-title
* {{medline-title
|title=Essential role for the TRF2 telomere protein in adult skin homeostasis.
|title=Inhibition of Mitochondrial Calcium Overload by SIRT3 Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue.
|date=08.2014
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24725274
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31712319
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326939
|full-text-url=https://sci-hub.do/10.2337/db19-0526
}}
}}
==TRA==
* {{medline-title
* {{medline-title
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|date=10.04.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
}}
}}
* {{medline-title
* {{medline-title
|title=Sex-specific regulation of aging in Caenorhabditis elegans.
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling.
|date=06.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29493066
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946081
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923
}}
}}
==MME==
* {{medline-title
* {{medline-title
|title=Age-Associated Decline in Thymic B Cell Expression of Aire and Aire-Dependent Self-Antigens.
|title=Geriatric Opioid Harm Reduction: Interprofessional Student Learning Outcomes.
|date=30.01.2018
|date=01-12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29386114
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32284953
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813500
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139179
}}
}}
* {{medline-title
* {{medline-title
|title=[Research of anti-aging mechanism of ginsenoside Rg1 on brain].
|title=Effectiveness of local anesthetic injection in geriatric patients following operative management of proximal and diaphyseal femur fracture.
|date=11.2014
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25850282
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31564373
 
|full-text-url=https://sci-hub.do/10.1016/j.injury.2019.09.013
}}
}}
* {{medline-title
* {{medline-title
|title=Post-mortem findings and piglet mortality in relation to strategic use of straw at farrowing.
|title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]]  accompanied with pro-tumorigenic secretome.
|date=01.05.2015
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25792335
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946
|full-text-url=https://sci-hub.do/10.1016/j.prevetmed.2015.02.023
|full-text-url=https://sci-hub.do/10.1002/ijc.32153
}}
}}
* {{medline-title
* {{medline-title
|title=TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons.
|title=Medial meniscus extrusion increases with age and BMI and is depending on different loading conditions.
|date=03.09.2014
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25186754
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29511818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262699
|full-text-url=https://sci-hub.do/10.1007/s00167-018-4885-7
}}
}}
==XPC==
==MOS==


* {{medline-title
* {{medline-title
|title=MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene [[XPC]] in Age-related Cataract.
|title=Effect of mannan oligosaccharides on the microbiota and productivity parameters of Litopenaeus vannamei shrimp under intensive cultivation in Ecuador.
|date=12.10.2018
|date=17.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30315181
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32066764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185952
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026423
}}
}}
* {{medline-title
* {{medline-title
|title=Global-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo Modifiers.
|title=Predictors of health-related quality of life among older adults living with HIV in Thailand: results from the baseline and follow-up surveys.
|date=2016
|date=23.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27200078
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31870166
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848295
|full-text-url=https://sci-hub.do/10.1080/09540121.2019.1707472
}}
}}
* {{medline-title
* {{medline-title
|title=Xeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulation.
|title=Comparison of health-related quality of life between the Han and Yi ethnicity elderly in the Yi autonomous areas of Yunnan Province.
|date=02.2016
|date=25.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26521083
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31766992
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713717
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878633
}}
}}
* {{medline-title
* {{medline-title
|title=Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes.
|title=Mannan oligosaccharide increases the growth performance, immunity and resistance capability against Vibro Parahemolyticus in juvenile abalone Haliotis discus hannai Ino.
|date=19.10.2015
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26477511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31561025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609912
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2019.09.058
}}
}}
* {{medline-title
==MRE11==
|title=[Role of DNA repair genes in radiation-induced changes of lifespan of Drosophila melanogaster].
|date=09-10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25775840


}}
* {{medline-title
* {{medline-title
|title=Defective mitophagy in [[XPA]] via PARP-1 hyperactivation and NAD( )/[[SIRT1]] reduction.
|title=Chromosomal alterations among age-related haematopoietic clones in Japan.
|date=08.05.2014
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24813611
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32581364
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625837
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489641
}}
}}
==YAP1==
* {{medline-title
* {{medline-title
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|date=25.06.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
}}
}}
* {{medline-title
* {{medline-title
|title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis.
|title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment.
|date=03.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527
}}
}}
* {{medline-title
* {{medline-title
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|title=Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells.
|date=05.2017
|date=01.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172637
}}
}}
==NEDD8==
* {{medline-title
* {{medline-title
|title=Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases [[MST1]] and MST2.
|title=Targeting Protein Neddylation for Cancer Therapy.
|date=01.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27940445
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31898235
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210079
|full-text-url=https://sci-hub.do/10.1007/978-981-15-1025-0_18
}}
}}
* {{medline-title
* {{medline-title
|title=Temporal and spatial expression of Smads and their correlation with [[YAP1]] expression in sheep.
|title=Effective targeting of the ubiquitin-like modifier [[NEDD8]] for lung adenocarcinoma treatment.
|date=26.08.2016
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27706608
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31907687
|full-text-url=https://sci-hub.do/10.4238/gmr.15037715
|full-text-url=https://sci-hub.do/10.1007/s10565-019-09503-6
}}
}}
* {{medline-title
* {{medline-title
|title=Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.
|title=Pevonedistat targeted therapy inhibits canine melanoma cell growth through induction of DNA re-replication and senescence.
|date=29.09.2015
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665821
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598835
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473101
}}
}}
==ABCA1==
 
* {{medline-title
* {{medline-title
|title=Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension.
|title=Protein neddylation and its alterations in human cancers for targeted therapy.
|date=01.07.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109455
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29331584
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.08.027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829022
}}
}}
==NNT==
* {{medline-title
* {{medline-title
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.
|title=Yoga, Health-Related Quality of Life and Mental Well-Being: A Re-analysis of a Meta-analysis Using the Quality Effects Model.
|date=08.2018
|date=16.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770
|full-text-url=https://sci-hub.do/10.1093/gerona/glz284
}}
}}
* {{medline-title
* {{medline-title
|title=Advanced glycation end products affect cholesterol homeostasis by impairing [[ABCA1]] expression on macrophages.
|title=Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database.
|date=08.2017
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28704619
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31647578
|full-text-url=https://sci-hub.do/10.1139/cjpp-2017-0170
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028025
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide DNA methylation profiles reveal novel candidate genes associated with meat quality at different age stages in hens.
|title=Years of Life Lost for Older Patients After Colorectal Cancer Diagnosis.
|date=05.04.2017
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28378745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30863872
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381223
|full-text-url=https://sci-hub.do/10.1007/s00268-019-04978-0
}}
}}
* {{medline-title
* {{medline-title
|title=Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice.
|title=Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet.
|date=15.01.2016
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26592663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30281804
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.11.064
|full-text-url=https://sci-hub.do/10.1111/jnc.14602
}}
}}
==ABCG2==
==NOTCH1==


* {{medline-title
* {{medline-title
|title=Contribution of senescence in human endometrial stromal cells during proliferative phase to embryo receptivity†.
|title=[How Does Aging Contribute to Cancer?]
|date=23.06.2020
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32285109
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33130684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313258
 
}}
}}
* {{medline-title
* {{medline-title
|title=[[ABCG2]] rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population.
|title=H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice.
|date=17.03.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32183743
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31609547
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778597
}}
}}
* {{medline-title
* {{medline-title
|title=Morphological and immunohistochemical characteristics of the equine corneal epithelium.
|title=Age-related remodelling of oesophageal epithelia by mutated cancer drivers.
|date=11.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30602793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900071
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0811-x
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life.
|title=Dynamic regulation of [[NOTCH1]] activation and Notch ligand expression in human thymus development.
|date=07.2016
|date=13.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27103634
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30042180
|full-text-url=https://sci-hub.do/10.1124/dmd.115.068577
|full-text-url=https://sci-hub.do/10.1242/dev.165597
}}
}}
==NPC1==
* {{medline-title
* {{medline-title
|title=Gene specific epigenetic regulation of hepatic folate transport system is responsible for perturbed cellular folate status during aging and exogenous modulation.
|title=Evaluation of age of death in Niemann-Pick disease, type C: Utility of disease support group websites to understand natural history.
|date=06.2016
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26990146
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30850267
|full-text-url=https://sci-hub.do/10.1002/mnfr.201500991
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535124
}}
}}
==AIM2==
* {{medline-title
* {{medline-title
|title=Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of Apc  mice.
|title=AAV9 intracerebroventricular gene therapy improves lifespan, locomotor function and pathology in a mouse model of Niemann-Pick type C1 disease.
|date=11.04.2017
|date=01.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28397782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394268
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097154
}}
}}
* {{medline-title
* {{medline-title
|title=Reduced levels of cytosolic DNA sensor [[AIM2]] are associated with impaired cytokine responses in healthy elderly.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=06.2016
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26944367
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.02.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
* {{medline-title
* {{medline-title
|title=Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age.
|title=The adenosine A  receptor agonist T1-11 ameliorates neurovisceral symptoms and extends the lifespan of a mouse model of Niemann-Pick type C disease.
|date=2015
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448778
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29079454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596365
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2017.10.013
}}
}}
==NPS==
* {{medline-title
* {{medline-title
|title=Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa.
|title=Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging.
|date=02.2016
|date=28.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26197995
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923322
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712099
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438979
}}
}}
* {{medline-title
* {{medline-title
|title=DAMPs, ageing, and cancer: The 'DAMP Hypothesis'.
|title=Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults.
|date=11.2015
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25446804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30902566
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416066
|full-text-url=https://sci-hub.do/10.1016/j.jagp.2019.01.215
}}
}}
==ARMS2==
* {{medline-title
* {{medline-title
|title=Benefits, Potential Harms, and Optimal Use of Nutritional Supplementation for Preventing Progression of Age-Related Macular Degeneration.
|title=The course of neuropsychiatric symptoms in patients with dementia in primary care.
|date=03.2017
|date=31.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30517631
|full-text-url=https://sci-hub.do/10.1177/1060028016680643
|full-text-url=https://sci-hub.do/10.1093/fampra/cmy117
}}
}}
* {{medline-title
* {{medline-title
|title=A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging.
|title=Serum calcium levels and neuropsychological performance in depression and matched healthy controls: Reversal of correlation a marker of the aging cognitive clock?
|date=14.07.2016
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27500671
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587243
|full-text-url=https://sci-hub.do/10.3791/54136
|full-text-url=https://sci-hub.do/10.1016/j.psyneuen.2018.03.012
}}
}}
==NRAS==
* {{medline-title
* {{medline-title
|title=Mesopic Pelli-Robson contrast sensitivity and MP-1 microperimetry in healthy ageing and age-related macular degeneration.
|title=Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor.
|date=12.2016
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27225020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32558183
|full-text-url=https://sci-hub.do/10.1111/aos.13112
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669612
}}
}}
* {{medline-title
* {{medline-title
|title=[Age-related Macular Degeneration in the Japanese].
|title=STAT3 Relays a Differential Response to Melanoma-Associated [i][[NRAS]][/i] Mutations.
|date=03.2016
|date=02.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27164756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31906480
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016650
}}
}}
* {{medline-title
* {{medline-title
|title=Prevalence and Genetic Characteristics of Geographic Atrophy among Elderly Japanese with Age-Related Macular Degeneration.
|title=Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study.
|date=2016
|date=08.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26918864
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31703632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842226
}}
}}
==ASXL1==
* {{medline-title
* {{medline-title
|title=[[ASXL1]] mutation in clonal hematopoiesis.
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|date=03.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31945396
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|full-text-url=https://sci-hub.do/10.1016/j.exphem.2020.01.002
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
}}
}}
==OTC==
* {{medline-title
* {{medline-title
|title=[Role of [[ASXL1]] mutations in hematological disorders].
|title=Age and growth of stocked juvenile Shoal Bass in a tailwater: Environmental variation and accuracy of daily age estimates.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31281161
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31644599
|full-text-url=https://sci-hub.do/10.11406/rinketsu.60.680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808449
}}
}}
* {{medline-title
* {{medline-title
|title=Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development.
|title=Comprehensive characterization of ureagenesis in the spf  mouse, a model of human ornithine transcarbamylase deficiency, reveals age-dependency of ammonia detoxification.
|date=06.2019
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30417440
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30714172
|full-text-url=https://sci-hub.do/10.1002/jcp.27752
|full-text-url=https://sci-hub.do/10.1002/jimd.12068
}}
}}
* {{medline-title
* {{medline-title
|title=A primer for epigenetics of hematological malignancies.
|title=Patterns and Perceptions of Self-Management for Osteoarthritis Pain in African American Older Adults.
|date=2016
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27725578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541043
|full-text-url=https://sci-hub.do/10.11406/rinketsu.57.1835
|full-text-url=https://sci-hub.do/10.1093/pm/pny260
}}
}}
* {{medline-title
* {{medline-title
|title=The [[BAP1]]/[[ASXL2]] Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.
|title=Use of over the counter products in older cardiovascular patients admitted to a tertiary care center in USA.
|date=27.11.2015
|date=04.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416890
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278107
}}
}}
==BID==
==PARP1==


* {{medline-title
* {{medline-title
|title=Dabigatran etexilate: appropriate use in patients with chronic kidney disease and in the elderly patients.
|title=Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections.
|date=06.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439778
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285747
|full-text-url=https://sci-hub.do/10.1007/s11739-017-1660-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591813
}}
}}
* {{medline-title
* {{medline-title
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|title=[[PARP1]] inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD  levels and increasing [[SIRT1]] activity.
|date=10.2016
|date=23.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30139380
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107962
}}
}}
* {{medline-title
* {{medline-title
|title=Rationale for the Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects Trial (POST5).
|title=Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice.
|date=04.2016
|date=13.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26995374
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29137352
|full-text-url=https://sci-hub.do/10.1016/j.ahj.2016.01.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663524
}}
}}
* {{medline-title
* {{medline-title
|title=The geriatric mania asenapine study (GeMS).
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|date=05-06.2016
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26952385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|full-text-url=https://sci-hub.do/10.1016/j.archger.2016.01.012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
}}
}}
* {{medline-title
==PCSK9==
|title=The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25910621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854160
}}
==CCR6==


* {{medline-title
* {{medline-title
|title=Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells.
|title=Lipoprotein removal mechanisms and aging: implications for the cardiovascular health of the elderly.
|date=07.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696983
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32011347
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474
|full-text-url=https://sci-hub.do/10.1097/MED.0000000000000529
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|title=The role of proprotein convertase subtilisin-kexin type 9 ([[PCSK9]]) in the vascular aging process - is there a link?
|date=19.01.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31708986
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836637
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects.
|title=[[PCSK9]] Inhibitors Show Value for Patients and the US Health Care System.
|date=10.2016
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27190305
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29241886
|full-text-url=https://sci-hub.do/10.1189/jlb.5A0116-025R
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929151
}}
}}
* {{medline-title
* {{medline-title
|title=Double negative (IgG IgD-CD27-) B cells are increased in a cohort of moderate-severe Alzheimer's disease patients and show a pro-inflammatory trafficking receptor phenotype.
|title=Association between lipoprotein (a) and proprotein convertase substilisin/kexin type 9 in patients with heterozygous familial hypercholesterolemia: A case-control study.
|date=2015
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25408215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129821
|full-text-url=https://sci-hub.do/10.3233/JAD-142412
|full-text-url=https://sci-hub.do/10.1016/j.metabol.2017.11.004
}}
}}
* {{medline-title
==PDK1==
|title=Trafficking phenotype and production of granzyme B by double negative B cells (IgG( )IgD(-)CD27(-)) in the elderly.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24389059
|full-text-url=https://sci-hub.do/10.1016/j.exger.2013.12.011
}}
==CD2AP==


* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=Inhibition of 3-phosphoinositide-dependent protein kinase 1 ([[PDK1]]) can revert cellular senescence in human dermal fibroblasts.
|date=28.03.2018
|date=08.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33229519
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://sci-hub.do/10.1073/pnas.1920338117
}}
}}
* {{medline-title
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|title=The Impact of the PI3K/Akt Signaling Pathway in Anxiety and Working Memory in Young and Middle-Aged [[PDK1]] K465E Knock-In Mice.
|date=11.04.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32457586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225327
}}
}}
* {{medline-title
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|title=Vps15 is critical to mediate autophagy in AngII treated HUVECs probably by [[PDK1]]/PKC signaling pathway.
|date=04.2016
|date=15.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31356904
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116701
}}
}}
* {{medline-title
* {{medline-title
|title=HYDRA: Revealing heterogeneity of imaging and genetic patterns through a multiple max-margin discriminative analysis framework.
|title=Acupuncture Administration Improves Cognitive Functions and Alleviates Inflammation and Nuclear Damage by Regulating Phosphatidylinositol 3 Kinase (PI3K)/Phosphoinositol-Dependent Kinase 1 ([[PDK1]])/Novel Protein Kinase C (nPKC)/Rac 1 Signaling Pathway in Senescence-Accelerated Prone 8 (SAM-P8) Mice.
|date=15.01.2017
|date=01.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26923371
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31152645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408358
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559003
}}
}}
* {{medline-title
==PGF==
|title=Dendrin ablation prolongs life span by delaying kidney failure.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26073036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530132
}}
==CD74==


* {{medline-title
* {{medline-title
|title=Identification of a conserved gene signature associated with an exacerbated inflammatory environment in the hippocampus of aging rats.
|title=Long-Term Aspirin Administration Has No Effect on Erectile Function: Evidence from Adult Rats and Ageing Rat Model.
|date=04.2017
|date=28.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28085212
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138859
|full-text-url=https://sci-hub.do/10.1002/hipo.22703
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538637
}}
}}
* {{medline-title
* {{medline-title
|title=Intramembrane proteolysis within lysosomes.
|title=In Vitro and In Vivo Antioxidant Activities of the Flowers and Leaves from Paeonia rockii and Identification of Their Antioxidant Constituents by UHPLC-ESI-HRMS  via Pre-Column DPPH Reaction.
|date=12.2016
|date=12.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27143694
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29439520
|full-text-url=https://sci-hub.do/10.1016/j.arr.2016.04.012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017382
}}
}}
* {{medline-title
* {{medline-title
|title=Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue.
|title=Redox cycling induces spermptosis and necrosis in stallion spermatozoa while the hydroxyl radical (OH•) only induces spermptosis.
|date=09.2015
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26253138
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28833663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577010
|full-text-url=https://sci-hub.do/10.1111/rda.13052
}}
}}
* {{medline-title
* {{medline-title
|title=Macrophage migration inhibitory factor confers resistance to senescence through [[CD74]]-dependent AMPK-FOXO3a signaling in mesenchymal stem cells.
|title=Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis.
|date=22.04.2015
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25896286
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803166
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453287
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.07.043
}}
* {{medline-title
|title=Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease.
|date=15.03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24441872
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949087
}}
}}
==CDC42==
==PICALM==


* {{medline-title
* {{medline-title
|title=Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1.
|title=Genetic Association between Alzheimer's Disease Risk Variant of the [[PICALM]] Gene and Auditory Event-Related Potentials in Aging.
|date=05.09.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31487690
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472946
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756888
|full-text-url=https://sci-hub.do/10.1134/S0006297918090092
}}
}}
* {{medline-title
* {{medline-title
|title=Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies.
|title=Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
|date=20.10.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30341976
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224233
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354244
}}
}}
* {{medline-title
* {{medline-title
|title=The relationship between reproductive and biochemical ageing at the time of the menopausal transition.
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=11.2017
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28843511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.028
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
* {{medline-title
* {{medline-title
|title=Senescent cells communicate via intercellular protein transfer.
|title=Alterations in endocytic protein expression with increasing age in the transgenic APP695 V717I London mouse model of amyloid pathology: implications for Alzheimer's disease.
|date=15.04.2015
|date=18.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25854920
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28885485
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403256
|full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000861
}}
}}
* {{medline-title
==PIN1==
|title=A crucial role for [[CDC42]] in senescence-associated inflammation and atherosclerosis.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25057989
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109913
}}
==CTNNB1==


* {{medline-title
* {{medline-title
|title=[i][[TP53]][/i] Tumor-suppressor Gene Plays a Key Role in [[IGF1]] Signaling Pathway Related to the Aging of Human Melanocytes.
|title=Brain somatic mutations observed in Alzheimer's disease associated with aging and dysregulation of tau phosphorylation.
|date=05.2019
|date=12.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092438
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31300647
|full-text-url=https://sci-hub.do/10.21873/anticanres.13363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626023
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Class XI Myosins Contribute to Auxin Response and Senescence-Induced Cell Death in [i]Arabidopsis[/i].
|date=15.04.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30538710
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277483
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Effects of Melatonin and Its Underlying Mechanism on Ethanol-Stimulated Senescence and Osteoclastic Differentiation in Human Periodontal Ligament Cells and Cementoblasts.
|date=02.2018
|date=12.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29895782
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032161
}}
}}
* {{medline-title
* {{medline-title
|title=P4 medicine and osteoporosis: a systematic review.
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=12.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27873024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://sci-hub.do/10.1007/s00508-016-1125-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
}}
==PNN==
* {{medline-title
* {{medline-title
|title=Expression profile analysis of new candidate genes for the therapy of primary osteoporosis.
|title=Hyaluronan degradation and release of a hyaluronan-aggrecan complex from perineuronal nets in the aged mouse brain.
|date=2016
|date=28.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26914116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33253804
 
|full-text-url=https://sci-hub.do/10.1016/j.bbagen.2020.129804
}}
}}
==DLD==
* {{medline-title
* {{medline-title
|title=A preliminary study of cerebral blood flow, aging and dementia in people with Down syndrome.
|title=Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex.
|date=12.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32996650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706367
|full-text-url=https://sci-hub.do/10.1111/jir.12784
|full-text-url=https://sci-hub.do/10.1007/s12035-019-1499-0
}}
}}
* {{medline-title
* {{medline-title
|title=Premature senescence activation in [[DLD]]-1 colorectal cancer cells through adjuvant therapy to induce a miRNA profile modulating cellular death.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=08.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116375
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
* {{medline-title
* {{medline-title
|title=Immature Auditory Evoked Potentials in Children With Moderate-Severe Developmental Language Disorder.
|title=Age-dependent and region-specific alteration of parvalbumin neurons and perineuronal nets in the mouse cerebral cortex.
|date=13.07.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29974119
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29126935
|full-text-url=https://sci-hub.do/10.1044/2018_JSLHR-L-17-0420
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2017.11.001
}}
}}
* {{medline-title
==POLD1==
|title=Trifluridine/tipiracil increases survival rates in peritoneal dissemination mouse models of human colorectal and gastric cancer.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28693216
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494646
}}
* {{medline-title
|title=Age dynamics of DNA damage and CpG methylation in the peripheral blood leukocytes of mice.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25867117
|full-text-url=https://sci-hub.do/10.1016/j.mrfmmm.2015.03.006
}}
==DSP==


* {{medline-title
* {{medline-title
|title=Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions.
|title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes.
|date=10.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754798
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529
}}
}}
* {{medline-title
* {{medline-title
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease.
|title=[[POLD1]] deficiency is involved in cognitive function impairment in AD patients and SAMP8 mice.
|date=05.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30978525
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2019.108833
}}
}}
* {{medline-title
* {{medline-title
|title=Metabolic Syndrome Components Are Associated With Symptomatic Polyneuropathy Independent of Glycemic Status.
|title=[[E2F1]] mediates the downregulation of [[POLD1]] in replicative senescence.
|date=05.2016
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26965720
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30895337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839175
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588650
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of diarrhetic shellfish poisoning toxins and pectenotoxin-2 in the bottlenose dolphin (Tursiops truncatus) by liquid chromatography-tandem mass spectrometry.
|title=Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing.
|date=16.10.2015
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26381568
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29208544
|full-text-url=https://sci-hub.do/10.1016/j.chroma.2015.08.066
|full-text-url=https://sci-hub.do/10.1016/j.arr.2017.12.001
}}
}}
==POLG==
* {{medline-title
* {{medline-title
|title=Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances.
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|date=15.11.2014
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25403178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233240
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
}}
}}
==ERAS==
* {{medline-title
* {{medline-title
|title=Enhanced Recovery After Surgery: Are the Principles Applicable to Adult and Geriatric Acute Care and Trauma Surgery?
|title=Parkin does not prevent accelerated cardiac aging in mitochondrial DNA mutator mice.
|date=03.2019
|date=16.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30711234
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30990467
|full-text-url=https://sci-hub.do/10.1016/j.anclin.2018.10.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542612
}}
}}
* {{medline-title
* {{medline-title
|title=Prospective application of an implementation framework to improve postoperative nutrition care processes: Evaluation of a mixed methods implementation study.
|title=The effects of AICAR and rapamycin on mitochondrial function in immortalized mitochondrial DNA mutator murine embryonic fibroblasts.
|date=09.2018
|date=16.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30151938
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30177551
|full-text-url=https://sci-hub.do/10.1111/1747-0080.12464
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262855
}}
}}
* {{medline-title
* {{medline-title
|title=Enhanced Recovery After Surgery ([[ERAS]]) - The Evidence in Geriatric Emergency Surgery: A Systematic Review.
|title=Impact of exercise on oocyte quality in the [[POLG]] mitochondrial DNA mutator mouse.
|date=Sept-10.2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088554
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875308
|full-text-url=https://sci-hub.do/10.21614/chirurgia.112.5.546
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074767
}}
}}
==RAD51==
* {{medline-title
* {{medline-title
|title=Multimodal Rehabilitation in Geriatric Emergency Surgery.
|title=Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium.
|date=Sept-10.2017
|date=09.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31291576
|full-text-url=https://sci-hub.do/10.21614/chirurgia.112.5.558
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.06.043
}}
}}
* {{medline-title
* {{medline-title
|title=Surgical Stress Reduction in Elderly Patients Undergoing Elective Colorectal Laparoscopic Surgery within an [[ERAS]] Protocol.
|title=Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae.
|date=11-12.2016
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28044948
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075257
|full-text-url=https://sci-hub.do/10.21614/chirurgia.111.6.476
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563841
}}
}}
==ESR1==
* {{medline-title
* {{medline-title
|title=Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement.
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|date=05.01.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788639
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
}}
}}
* {{medline-title
* {{medline-title
|title=Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain.
|title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment.
|date=01.04.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28334178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527
}}
}}
==SATB1==
* {{medline-title
* {{medline-title
|title=Age- and menopause-related differences in subcutaneous adipose tissue estrogen receptor mRNA expression.
|title=Loss of [[SATB1]] Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons.
|date=05.2017
|date=03.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28288896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31543366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493192
}}
}}
* {{medline-title
* {{medline-title
|title=Association of PvuII and XbaI polymorphisms on estrogen receptor alpha ([[ESR1]]) gene to changes into serum lipid profile of post-menopausal women: Effects of aging, body mass index and breast cancer incidence.
|title=Transcriptomic analysis of human IL-7 receptor alpha   and  effector memory CD8  T cells reveals an age-associated signature linked to influenza vaccine response in older adults.
|date=2017
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199328
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310899
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612637
}}
}}
* {{medline-title
* {{medline-title
|title=Differential roles of estrogen receptors, [[ESR1]] and [[ESR2]], in adult rat spermatogenesis.
|title=Divergent [[SATB1]] expression across human life span and tissue compartments.
|date=15.06.2016
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27004961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30803026
|full-text-url=https://sci-hub.do/10.1016/j.mce.2016.03.024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618325
}}
}}
==FADD==
 
* {{medline-title
* {{medline-title
|title=Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal [[FADD]].
|title=Changes in expression of special AT-rich sequence binding protein 1 and phosphatase and tensin homologue in kidneys of diabetic rats during ageing.
|date=11.2018
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30138765
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29506055
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.07.014
|full-text-url=https://sci-hub.do/10.1093/ndt/gfy003
}}
}}
==SET==
* {{medline-title
* {{medline-title
|title=Decreased cortical [[FADD]] protein is associated with clinical dementia and cognitive decline in an elderly community sample.
|title=Chromatin Modifiers [[SET]]-25 and [[SET]]-32 Are Required for Establishment but Not Long-Term Maintenance of Transgenerational Epigenetic Inheritance.
|date=20.03.2017
|date=20.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28320441
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360099
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.10.085
}}
}}
* {{medline-title
* {{medline-title
|title=Chronic MDMA induces neurochemical changes in the hippocampus of adolescent and young adult rats: Down-regulation of apoptotic markers.
|title=[[SET]]-9 and [[SET]]-26 are H3K4me3 readers and play critical roles in germline development and longevity.
|date=07.2015
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26068050
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29714684
|full-text-url=https://sci-hub.do/10.1016/j.neuro.2015.06.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010342
}}
}}
* {{medline-title
* {{medline-title
|title=The Heart Protection Effect of Alcalase Potato Protein Hydrolysate Is through [[IGF1R]]-PI3K-Akt Compensatory Reactivation in Aging Rats on High Fat Diets.
|title=Muscle-Specific Histone H3K36 Dimethyltransferase [[SET]]-18 Shortens Lifespan of Caenorhabditis elegans by Repressing daf-16a Expression.
|date=05.05.2015
|date=06.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25950762
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29514099
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463638
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.02.029
}}
}}
* {{medline-title
* {{medline-title
|title=TNF/TNFR₁ pathway and endoplasmic reticulum stress are involved in ofloxacin-induced apoptosis of juvenile canine chondrocytes.
|title=Assessing efficacy of day 3 embryo time-lapse algorithms retrospectively: impacts of dataset type and confounding factors.
|date=15.04.2014
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24582689
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338469
|full-text-url=https://sci-hub.do/10.1016/j.taap.2014.02.003
|full-text-url=https://sci-hub.do/10.1080/14647273.2018.1425919
}}
}}
==FGA==
==SLA==


* {{medline-title
* {{medline-title
|title=Goal Pursuit, Goal Adjustment, and Pain in Middle-Aged Adults Aging With Physical Disability.
|title=Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity.
|date=12.2019
|date=14.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31718416
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32540272
|full-text-url=https://sci-hub.do/10.1177/0898264319827142
|full-text-url=https://sci-hub.do/10.1016/j.vaccine.2020.05.085
}}
}}
* {{medline-title
* {{medline-title
|title=Tenacious Goal Pursuit, Flexible Goal Adjustment, and Life Satisfaction Among Chinese Older Adult Couples.
|title=Mechanical Anisotropy and Surface Roughness in Additively Manufactured Parts Fabricated by Stereolithography ([[SLA]]) Using Statistical Analysis.
|date=01.2020
|date=30.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31547780
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32486137
|full-text-url=https://sci-hub.do/10.1177/0164027519876125
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321476
}}
}}
* {{medline-title
* {{medline-title
|title=Association of tenacious goal pursuit and flexible goal adjustment with out-of-home mobility among community-dwelling older people.
|title=The Effect of Age of Titanium Dental Implants on Implant Survival and Marginal Bone Resorption: A 5-Year Retrospective Follow-Up Study.
|date=09.2019
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30449015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32369581
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682663
|full-text-url=https://sci-hub.do/10.1563/aaid-joi-D-19-00316
}}
}}
* {{medline-title
* {{medline-title
|title=Assimilative and accommodative coping in older adults with and without sensory impairment: four-year change and prospective relations with affective well-being.
|title="Spirometric" lung age reference equations: A narrative review.
|date=09.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30407084
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28870870
|full-text-url=https://sci-hub.do/10.1080/13607863.2018.1479833
|full-text-url=https://sci-hub.do/10.1016/j.resp.2017.08.018
}}
}}
* {{medline-title
==SMS==
|title=Age stereotypes, flexible goal adjustment, and well-being among Chinese older adults.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635315
|full-text-url=https://sci-hub.do/10.1080/13548506.2017.1344253
}}
==FGR==


* {{medline-title
* {{medline-title
|title=Aurora kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction.
|title=Does a Live Performance Impact Synchronization to Musical Rhythm in Cognitively Impaired Elderly?
|date=06.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32452402
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33104027
|full-text-url=https://sci-hub.do/10.1016/j.placenta.2020.04.012
|full-text-url=https://sci-hub.do/10.3233/JAD-200521
}}
}}
* {{medline-title
* {{medline-title
|title=Premature Vascular Aging in Guinea Pigs Affected by Fetal Growth Restriction.
|title=Testing the effectiveness of physical activity advice delivered via text messaging vs. human phone advisors in a Latino population: The On The Move randomized controlled trial design and methods.
|date=15.07.2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31311132
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659437
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351675
}}
}}
* {{medline-title
* {{medline-title
|title=Premature placental aging in term small-for-gestational-age and growth-restricted fetuses.
|title=Mobile Health Interventions for Physical Activity, Sedentary Behavior, and Sleep in Adults Aged 50 Years and Older: A Systematic Literature Review.
|date=05.2019
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125412
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30507266
|full-text-url=https://sci-hub.do/10.1002/uog.20103
|full-text-url=https://sci-hub.do/10.1123/japa.2017-0410
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of fertility treatment on adverse perinatal outcomes in women aged at least 40 years.
|title=Senescence-messaging secretome factors trigger premature senescence in human endometrium-derived stem cells.
|date=01.2018
|date=19.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994115
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397942
|full-text-url=https://sci-hub.do/10.1002/ijgo.12345
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.163
}}
}}
* {{medline-title
==SOD3==
|title=Seroprevalence of spotted fever group Rickettsiae in dogs in Germany.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25793474
|full-text-url=https://sci-hub.do/10.1089/vbz.2014.1715
}}
==FOXA1==


* {{medline-title
* {{medline-title
|title=Analyses of an epigenetic switch involved in the activation of pioneer factor [[FOXA1]] leading to the prognostic value of estrogen receptor and [[FOXA1]] co-expression in breast cancer.
|title=Prenatal hypoxia affected endothelium-dependent vasodilation in mesenteric arteries of aged offspring via increased oxidative stress.
|date=28.09.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562808
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30617312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782010
|full-text-url=https://sci-hub.do/10.1038/s41440-018-0181-7
}}
}}
* {{medline-title
* {{medline-title
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
|title=Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage.
|date=05.06.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222787
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141073
}}
}}
* {{medline-title
* {{medline-title
|title=[[FOXA1]] and [[SOX9]] Expression in the Developing Urogenital Sinus of the Tammar Wallaby (Macropus eugenii).
|title=In silico analysis and molecular dynamics simulation of human superoxide dismutase 3 ([[SOD3]]) genetic variants.
|date=2015
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26406875
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206983
|full-text-url=https://sci-hub.do/10.1159/000439499
|full-text-url=https://sci-hub.do/10.1002/jcb.27636
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=03.2015
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1134/S0006297915030062
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
* {{medline-title
|title=Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-[[MADD]] locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066205
}}
}}
==FOXN1==
==SOX9==


* {{medline-title
* {{medline-title
|title=Thymic rejuvenation via [[FOXN1]]-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation.
|title=Positive Effects of a Young Systemic Environment and High Growth Differentiation Factor 11 Levels on Chondrocyte Proliferation and Cartilage Matrix Synthesis in Old Mice.
|date=17.09.2020
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32790650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32067417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526556
|full-text-url=https://sci-hub.do/10.1002/art.41230
}}
}}
* {{medline-title
* {{medline-title
|title=Role of Bone Marrow Maturity, Insulin-Like Growth Factor 1 Receptor, and Forkhead Box Protein N1 in Thymic Involution and Rejuvenation.
|title=Epigenetic Mechanisms Underlying the Aging of Articular Cartilage and Osteoarthritis.
|date=10.2016
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27145342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30970348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097038
|full-text-url=https://sci-hub.do/10.1159/000496688
}}
}}
* {{medline-title
* {{medline-title
|title=Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution.
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|date=2016
|date=26.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26983083
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794177
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
}}
}}
* {{medline-title
* {{medline-title
|title=A deletion in [[FOXN1]] is associated with a syndrome characterized by congenital hypotrichosis and short life expectancy in Birman cats.
|title=Role of CD133 Molecule in Wnt Response and Renal Repair.
|date=2015
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25781316
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29431914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363148
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827750
}}
}}
* {{medline-title
==TIGIT==
|title=Regeneration of the aged thymus by a single transcription factor.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24715454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978836
}}
==FOXO6==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma.
|date=15.11.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30768970
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1016/j.jtho.2019.01.024
}}
}}
* {{medline-title
* {{medline-title
|title=Introduction to FOXO Biology.
|title=Multivariate Computational Analysis of Gamma Delta T Cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV+ Aging.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414140
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-8900-3_1
}}
* {{medline-title
|title=FOXO in Neural Cells and Diseases of the Nervous System.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433734
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30568654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290897
}}
}}
* {{medline-title
* {{medline-title
|title=FOXO Transcriptional Factors and Long-Term Living.
|title=Characterization of Blimp-1 function in effector regulatory T cells.
|date=2017
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29724515
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574317
|full-text-url=https://sci-hub.do/10.1016/j.jaut.2018.04.003
}}
}}
* {{medline-title
* {{medline-title
|title=Long live FOXO: unraveling the role of FOXO proteins in aging and longevity.
|title=T-cell Immunoglobulin and ITIM Domain Contributes to CD8  T-cell Immunosenescence.
|date=04.2016
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26643314
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29349889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783344
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847879
}}
}}
==GCLC==
==TRPA1==


* {{medline-title
* {{medline-title
|title=Aerobic exercise training partially reverses the impairment of Nrf2 activation in older humans.
|title=Important regulatory function of transient receptor potential ankyrin 1 receptors in age-related learning and memory alterations of mice.
|date=20.11.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32866619
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885083
}}
}}
* {{medline-title
* {{medline-title
|title=Ontogeny and aging of Nrf2 pathway genes in livers of rats.
|title=Aging of mouse intervertebral disc and association with back pain.
|date=15.06.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29689272
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30936040
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2018.04.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549718
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Congeneric variability in lifespan extension and onset of senescence suggest active regulation of aging in response to low temperature.
|date=02.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399408
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336457
}}
}}
* {{medline-title
* {{medline-title
|title=Increase in Blood Glutathione and Erythrocyte Proteins Related to Glutathione Generation, Reduction and Utilization in African-American Old Women with Diabetes.
|title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases.
|date=2015
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26770888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710176
|full-text-url=https://sci-hub.do/10.1111/nmo.13185
}}
}}
* {{medline-title
==TRPV4==
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201
}}
==GEM==


* {{medline-title
* {{medline-title
|title=The Impact of Geriatric Emergency Management Nurses on the Care of Frail Older Patients in the Emergency Department: a Systematic Review.
|title=[[TRPV4]] receptor as a functional sensory molecule in bladder urothelium: Stretch-independent, tissue-specific actions and pathological implications.
|date=09.2020
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32904804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31914645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973053
}}
}}
* {{medline-title
* {{medline-title
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|title=Exercise restores impaired endothelium-derived hyperpolarizing factor-mediated vasodilation in aged rat aortic arteries via the [[TRPV4]]-K 2.3 signaling complex.
|date=09.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31564840
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731547
}}
}}
* {{medline-title
* {{medline-title
|title=Understanding of diagnosis and medications among non-English-speaking older patients.
|title=Autonomic dysregulation at multiple sites is implicated in age-associated underactive bladder in female mice.
|date=06.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377482
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30932250
|full-text-url=https://sci-hub.do/10.1111/ajag.12503
|full-text-url=https://sci-hub.do/10.1002/nau.23990
}}
}}
* {{medline-title
* {{medline-title
|title=Increased gait variability may not imply impaired stride-to-stride control of walking in healthy older adults: Winner: 2013 Gait and Clinical Movement Analysis Society Best Paper Award.
|title=Reduced bladder responses to capsaicin and GSK-1016790A in retired-breeder female rats with diminished volume sensitivity.
|date=06.2017
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28454071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019934
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869351
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00198.2018
}}
}}
==TSC2==
* {{medline-title
* {{medline-title
|title=The development and evaluation of mini-[[GEM]]s - short, focused, online e-learning videos in geriatric medicine.
|title=AMPK/[[TSC2]]/mTOR pathway regulates replicative senescence of human vascular smooth muscle cells.
|date=04-06.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27050439
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30542441
|full-text-url=https://sci-hub.do/10.1080/02701960.2016.1165217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257130
}}
}}
==GGCT==
* {{medline-title
* {{medline-title
|title=Blockade of γ-Glutamylcyclotransferase Enhances Docetaxel Growth Inhibition of Prostate Cancer Cells.
|title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging.
|date=09.2019
|date=25.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31519583
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750
|full-text-url=https://sci-hub.do/10.21873/anticanres.13666
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052
}}
}}
* {{medline-title
* {{medline-title
|title=Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase ([[GGCT]]): A Novel Molecular Target for Anticancer Therapy.
|title=[[FTO]] is involved in Alzheimer's disease by targeting [[TSC1]]-mTOR-Tau signaling.
|date=14.07.2018
|date=25.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30011933
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073726
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.02.201
}}
}}
* {{medline-title
* {{medline-title
|title=Depletion of gamma-glutamylcyclotransferase in cancer cells induces autophagy followed by cellular senescence.
|title=Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner.
|date=2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29736310
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29023667
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716871
}}
}}
==A2M==
* {{medline-title
* {{medline-title
|title=Prohibitin-2 is a novel regulator of p21  induced by depletion of γ-glutamylcyclotransferase.
|title=Age-Dependent Variation in Glycosylation Features of Alpha-2-Macroglobulin.
|date=29.01.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29307834
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31489526
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.029
|full-text-url=https://sci-hub.do/10.1007/s12013-019-00883-4
}}
}}
* {{medline-title
* {{medline-title
|title=Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation.
|title=[[MMP2]]-[[A2M]] interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction.
|date=22.09.2016
|date=19.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27658708
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29464020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814160
}}
}}
==GPX4==
* {{medline-title
* {{medline-title
|title=l-carnitine supplementation during in vitro culture regulates oxidative stress in embryos from bovine aged oocytes.
|title=[[SPARCL1]] Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging.
|date=02.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31837632
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154276
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2019.11.036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934753
}}
}}
==ABCA7==
* {{medline-title
* {{medline-title
|title=Dietary Selenium Supplementation Ameliorates Female Reproductive Efficiency in Aging Mice.
|title=New genetic players in late-onset Alzheimer's disease: Findings of genome-wide association studies.
|date=11.12.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31835711
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30381536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206761
}}
}}
* {{medline-title
* {{medline-title
|title=Resveratrol improves in vitro maturation of oocytes in aged mice and humans.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=05.2018
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.01.020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
* {{medline-title
* {{medline-title
|title=Differential menopause- versus aging-induced changes in oxidative stress and circadian rhythm gene markers.
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=06.2017
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28408140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.04.002
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
==ABCG2==
* {{medline-title
* {{medline-title
|title=Maternal obesity in the rat impairs male offspring aging of the testicular antioxidant defence system.
|title=Contribution of senescence in human endometrial stromal cells during proliferative phase to embryo receptivity†.
|date=09.2017
|date=23.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28063465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32285109
|full-text-url=https://sci-hub.do/10.1071/RD16277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313258
}}
}}
==HMGB2==
* {{medline-title
* {{medline-title
|title=Loss of Endogenous [[HMGB2]] Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice.
|title=[[ABCG2]] rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population.
|date=25.01.2019
|date=17.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30487376
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32183743
|full-text-url=https://sci-hub.do/10.1253/circj.CJ-18-0925
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077001
}}
}}
* {{medline-title
* {{medline-title
|title=[[HMGB2]] Loss upon Senescence Entry Disrupts Genomic Organization and Induces [[CTCF]] Clustering across Cell Types.
|title=Morphological and immunohistochemical characteristics of the equine corneal epithelium.
|date=17.05.2018
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706538
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767359
|full-text-url=https://sci-hub.do/10.1016/j.molcel.2018.03.030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900071
}}
}}
==ACLY==
* {{medline-title
* {{medline-title
|title=Correlations between age, functional status, and the senescence-associated proteins [[HMGB2]] and p16 .
|title=In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase.
|date=04.2018
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29651745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32666259
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964056
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527365
}}
}}
* {{medline-title
* {{medline-title
|title=Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence.
|title=Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes.
|date=30.04.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935093
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2019.01.005
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of Endometrial Plasticity in Recurrent Pregnancy Loss.
|title=Spermidine reduces cancer-related mortality in humans.
|date=02.2016
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26418742
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354939
|full-text-url=https://sci-hub.do/10.1002/stem.2222
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333461
}}
}}
==IGF2==
==ACTN3==


* {{medline-title
* {{medline-title
|title=Paternal Insulin-like Growth Factor 2 (Igf2) Regulates Stem Cell Activity During Adulthood.
|title=The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature.
|date=02.2017
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28007480
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30676214
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233811
|full-text-url=https://sci-hub.do/10.1123/japa.2018-0155
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing.
|title=Is evolutionary loss our gain? The role of [[ACTN3]] p.Arg577Ter (R577X) genotype in athletic performance, ageing, and disease.
|date=09.2016
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27294501
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30281865
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983298
|full-text-url=https://sci-hub.do/10.1002/humu.23663
}}
}}
* {{medline-title
* {{medline-title
|title=Autocrine Action of [[IGF2]] Regulates Adult β-Cell Mass and Function.
|title=[[ACTN3]] genotype and physical function and frailty in an elderly Chinese population: the Rugao Longevity and Ageing Study.
|date=12.2015
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26384384
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29447359
|full-text-url=https://sci-hub.do/10.2337/db14-1735
|full-text-url=https://sci-hub.do/10.1093/ageing/afy007
}}
* {{medline-title
|title=Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex.
|date=07.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26100875
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500222
}}
}}
* {{medline-title
==ADM==
|title=miR-30e targets [[IGF2]]-regulated osteogenesis in bone marrow-derived mesenchymal stem cells, aortic smooth muscle cells, and ApoE-/- mice.
|date=01.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25678587
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375408
}}
==IK==


* {{medline-title
* {{medline-title
|title=Pial Collateral Reactivity During Hypertension and Aging: Understanding the Function of Collaterals for Stroke Therapy.
|title=Assessment of age-related differences in decomposition-based quantitative EMG in the intrinsic hand muscles: A multivariate approach.
|date=06.2016
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27103017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32693193
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878286
|full-text-url=https://sci-hub.do/10.1016/j.clinph.2020.06.017
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelium-dependent hyperpolarization: age, gender and blood pressure, do they matter?
|title=Evaluation of transcriptional levels of the natriuretic peptides, endothelin-1, adrenomedullin, their receptors and long non-coding RNAs in rat cardiac tissue as cardiovascular biomarkers of aging.
|date=01.2017
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26548576
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31629715
|full-text-url=https://sci-hub.do/10.1111/apha.12628
|full-text-url=https://sci-hub.do/10.1016/j.peptides.2019.170173
}}
}}
* {{medline-title
* {{medline-title
|title=17β-estradiol potentiates endothelium-dependent nitric oxide- and hyperpolarization-mediated relaxations in blood vessels of male but not female apolipoprotein-E deficient mice.
|title=Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti.
|date=08.2015
|date=16.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25869512
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146940
|full-text-url=https://sci-hub.do/10.1016/j.vph.2015.02.009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691197
}}
}}
==AGA==
* {{medline-title
* {{medline-title
|title=Altered neutrophil functions in elderly patients during a 6-month follow-up period after a hip fracture.
|title=Relationship between androgenic alopecia and white matter hyperintensities in apparently healthy subjects.
|date=05.2015
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25797136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250269
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.03.009
|full-text-url=https://sci-hub.do/10.1007/s11682-019-00147-y
}}
}}
* {{medline-title
* {{medline-title
|title=Microglial K( ) channel expression in young adult and aged mice.
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|date=04.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25472417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359010
}}
==IL2==


* {{medline-title
|title=Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33193368
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662090
}}
}}
* {{medline-title
* {{medline-title
|title=Redox, immune and genetic biomarker system for personalized treatments in colorectal cancer.
|title=The Impact of Being Born Preterm or Small for Gestational Age on Early Vascular Aging in Adolescents.
|date=15.02.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30788039
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29960764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379753
|full-text-url=https://sci-hub.do/10.1016/j.jpeds.2018.05.056
}}
}}
==ALB==
* {{medline-title
* {{medline-title
|title=Low IL-2 Expressing T Cells in Thalassemia Major Patients: Is It Immune Aging.
|title=Effects of Age on Inflammatory Profiles and Nutrition/Energy Metabolism in Domestic Cats.
|date=10.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30369736
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33262938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695597
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic repression of interleukin 2 expression in senescent CD4  T cells during chronic HIV type 1 infection.
|title=Blood Chemistry Reference Values for Free-Ranging Asiatic Black Bears ( Ursus thibetanus) by Season, Age, and Sex.
|date=01.01.2015
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25001463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29671714
|full-text-url=https://sci-hub.do/10.1093/infdis/jiu376
|full-text-url=https://sci-hub.do/10.7589/2017-08-201
}}
}}
* {{medline-title
* {{medline-title
|title=Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life.
|title=Higher serum albumin was related with diabetes incidence and the impact of BMI changes: Based on cohort study of 18,384 Chinese male elderly.
|date=06.2014
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24370373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29033312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003347
|full-text-url=https://sci-hub.do/10.1016/j.jdiacomp.2017.08.015
}}
}}
==IRS2==
==ASXL1==


* {{medline-title
* {{medline-title
|title=Effects of Heshouwuyin on gene expression of the insulin/IGF signalling pathway in rat testis and spermatogenic cells.
|title=[[ASXL1]] mutation in clonal hematopoiesis.
|date=12.2020
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33264567
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31945396
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717869
|full-text-url=https://sci-hub.do/10.1016/j.exphem.2020.01.002
}}
}}
* {{medline-title
* {{medline-title
|title=Involvement of insulin receptor substrates in cognitive impairment and Alzheimer's disease.
|title=[Role of [[ASXL1]] mutations in hematological disorders].
|date=08.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30964050
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31281161
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524492
|full-text-url=https://sci-hub.do/10.11406/rinketsu.60.680
}}
}}
* {{medline-title
* {{medline-title
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|title=Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development.
|date=06.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30417440
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
|full-text-url=https://sci-hub.do/10.1002/jcp.27752
}}
}}
==ATRX==
* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=[[ATRX]]-[[DAXX]] Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains.
|date=02.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31361513
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://sci-hub.do/10.1089/dna.2019.4752
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of [[MTNR1B]] gene polymorphisms in relationship with [[IRS2]] gene variants, epicardial fat thickness, glucose homeostasis and cognitive performance in the elderly.
|title=Inactivation of hepatic [[ATRX]] in [i]Atrx[/i] Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine.
|date=2017
|date=07.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708046
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883366
|full-text-url=https://sci-hub.do/10.1080/07420528.2017.1340894
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046231
}}
}}
==JAK1==
* {{medline-title
* {{medline-title
|title=Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling.
|title=Mechanistic understanding of the role of [[ATRX]] in senescence provides new insight for combinatorial therapies with [[CDK4]] inhibitors.
|date=01.05.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32233952
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29404388
|full-text-url=https://sci-hub.do/10.1152/ajpcell.00520.2019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791849
}}
}}
==BAD==
* {{medline-title
* {{medline-title
|title=The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Through [[JAK1]].
|title=I  imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway.
|date=2019
|date=31.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396213
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33128688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6665952
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00281-2
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of age and renal impairment on the steady state pharmacokinetics of filgotinib, a selective [[JAK1]] inhibitor.
|title=Xanthohumol exerts protective effects in liver alterations associated with aging.
|date=12.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088677
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29536163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256002
|full-text-url=https://sci-hub.do/10.1007/s00394-018-1657-6
}}
}}
* {{medline-title
* {{medline-title
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|title=Protective effect of xanthohumol against age-related brain damage.
|date=04.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011
}}
}}
* {{medline-title
==BATF==
|title=Interferon-γ induces senescence in normal human melanocytes.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24681574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969336
}}
==LRP1==


* {{medline-title
* {{medline-title
|title=Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome.
|title=LncRNA-ES3 inhibition by Bhlhe40 is involved in high glucose-induced calcification/senescence of vascular smooth muscle cells.
|date=06.2020
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268785
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32483833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255962
|full-text-url=https://sci-hub.do/10.1111/nyas.14381
}}
}}
* {{medline-title
* {{medline-title
|title=LXR activation protects hippocampal microvasculature in very old triple transgenic mouse model of Alzheimer's disease.
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|date=16.05.2016
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27057732
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2016.04.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
}}
* {{medline-title
|title=Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal [[LRP1]].
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26688581
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761336
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats.
|title=Transcriptomic analysis of human IL-7 receptor alpha  and   effector memory CD8  T cells reveals an age-associated signature linked to influenza vaccine response in older adults.
|date=20.05.2015
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782004
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612637
}}
}}
==BLM==
* {{medline-title
* {{medline-title
|title=Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice.
|title=[Olmesartan inhibits age-associated migration and invasion of human aortic vascular smooth muscle cells by upregulating miR-3133 axis].
|date=10.10.2014
|date=30.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25301084
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32895132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192620
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225100
}}
}}
==MAL==
* {{medline-title
* {{medline-title
|title=Daylight photodynamic therapy versus cryosurgery for the treatment and prophylaxis of actinic keratoses of the face - protocol of a multicenter, prospective, randomized, controlled, two-armed study.
|title=Genomic instability and DNA replication defects in progeroid syndromes.
|date=25.10.2017
|date=31.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29070025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29936894
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000143
}}
}}
* {{medline-title
* {{medline-title
|title=Infant Nutritional Status, Feeding Practices, Enteropathogen Exposure, Socioeconomic Status, and Illness Are Associated with Gut Barrier Function As Assessed by the Lactulose Mannitol Test in the [[MAL]]-ED Birth Cohort.
|title=Human RecQL4 helicase plays multifaceted roles in the genomic stability of normal and cancer cells.
|date=07.2017
|date=28.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28719336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508897
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2017.10.021
}}
}}
==BMI1==
* {{medline-title
* {{medline-title
|title=Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis.
|title=Senescence Induced by [[BMI1]] Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
|date=19.07.2015
|date=20.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26056366
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33086074
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574900
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|date=07.2015
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25846207
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|full-text-url=https://sci-hub.do/10.1007/s12576-015-0373-8
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
}}
}}
* {{medline-title
* {{medline-title
|title=Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications.
|title=Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein [[BMI1]] in breast cancer cells.
|date=06.2015
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25817264
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528145
|full-text-url=https://sci-hub.do/10.1111/jocd.12135
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986597
}}
}}
==MLN==
==BMP2==


* {{medline-title
* {{medline-title
|title=Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.
|title=Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells.
|date=2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849526
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32126555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432217
|full-text-url=https://sci-hub.do/10.1159/000504298
}}
}}
* {{medline-title
* {{medline-title
|title=Variability of Spleen and Mesenteric Lymph Node in Control Cynomolgus Monkeys ( Macaca fascicularis) from Nonclinical Safety Studies: A Retrospective Assessment.
|title=Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging.
|date=01.2019
|date=03.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30563426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352426
|full-text-url=https://sci-hub.do/10.1177/0192623318809073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264619
}}
}}
* {{medline-title
* {{medline-title
|title=Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life.
|title=Synthesis of Extracellular Pyrophosphate Increases in Vascular Smooth Muscle Cells During Phosphate-Induced Calcification.
|date=03.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30523311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375790
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.311444
}}
}}
==BMP4==
* {{medline-title
* {{medline-title
|title=Immunological Basis for Rapid Progression of Diabetes in Older NOD Mouse Recipients Post BM-HSC Transplantation.
|title=Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome.
|date=2015
|date=08.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26020954
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32896271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447290
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478891
}}
}}
* {{medline-title
* {{medline-title
|title=Targeting protein neddylation with an [[NEDD8]]-activating enzyme inhibitor [[MLN]]4924 induced apoptosis or senescence in human lymphoma cells.
|title=Interplay between Follistatin, Activin A, and [[BMP4]] Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging.
|date=2015
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782162
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623239
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.05.045
}}
}}
==MME==
* {{medline-title
* {{medline-title
|title=Geriatric Opioid Harm Reduction: Interprofessional Student Learning Outcomes.
|title=Centenarians Overexpress Pluripotency-Related Genes.
|date=01-12.2020
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32284953
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139179
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
}}
}}
==BPI==
* {{medline-title
* {{medline-title
|title=Effectiveness of local anesthetic injection in geriatric patients following operative management of proximal and diaphyseal femur fracture.
|title=High TARC plasma levels confer protection to long living individuals by inducing M2 profile.
|date=11.2019
|date=01.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31564373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002742
|full-text-url=https://sci-hub.do/10.1016/j.injury.2019.09.013
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155305
}}
}}
* {{medline-title
* {{medline-title
|title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]] accompanied with pro-tumorigenic secretome.
|title=Circulating [[BPI]]FB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals.
|date=01.08.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32547549
|full-text-url=https://sci-hub.do/10.1002/ijc.32153
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272600
}}
}}
* {{medline-title
* {{medline-title
|title=Medial meniscus extrusion increases with age and BMI and is depending on different loading conditions.
|title=The effect of postural deformities on back function and pain in patients with Parkinson's disease.
|date=08.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29511818
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31177242
|full-text-url=https://sci-hub.do/10.1007/s00167-018-4885-7
|full-text-url=https://sci-hub.do/10.3233/NRE-182637
}}
}}
* {{medline-title
==CCL3==
|title=Rare Variants in [[MME]], Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies.
|date=01.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27588448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011077
}}
==MVD==


* {{medline-title
* {{medline-title
|title=Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density.
|title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau.
|date=12.2018
|date=03.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297390
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082275
|full-text-url=https://sci-hub.do/10.1136/jim-2018-000804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978
}}
}}
* {{medline-title
* {{medline-title
|title=Assessing Microvascular Function in Humans from a Chronic Disease Perspective.
|title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles.
|date=12.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904002
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698072
|full-text-url=https://sci-hub.do/10.1620/tjem.245.29
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women.
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|date=08.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28316011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514208
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
}}
}}
==CCN1==
* {{medline-title
* {{medline-title
|title=Diffusion-weighted multiparametric MRI for monitoring longitudinal changes of parameters in rabbit VX2 liver tumors.
|title=Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis.
|date=09.2016
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26878263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32651107
|full-text-url=https://sci-hub.do/10.1002/jmri.25179
|full-text-url=https://sci-hub.do/10.1016/j.rbmo.2020.04.006
}}
}}
* {{medline-title
* {{medline-title
|title=[Expression of vascular endothelial growth factor and microvessel density in different brain regions in aged rats].
|title=Inhibition of cellular communication network factor 1 ([[CCN1]])-driven senescence slows down cartilage inflammaging and osteoarthritis.
|date=07.2014
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25080903
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32622876
|full-text-url=https://sci-hub.do/10.11817/j.issn.1672-7347.2014.07.005
|full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115522
}}
}}
==NEDD8==
* {{medline-title
* {{medline-title
|title=Targeting Protein Neddylation for Cancer Therapy.
|title=The senescence-associated matricellular protein [[CCN1]] in plasma of human subjects with idiopathic pulmonary fibrosis.
|date=2020
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31898235
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765873
|full-text-url=https://sci-hub.do/10.1007/978-981-15-1025-0_18
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023981
}}
}}
==CCNB1==
* {{medline-title
* {{medline-title
|title=Effective targeting of the ubiquitin-like modifier [[NEDD8]] for lung adenocarcinoma treatment.
|title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro.
|date=08.2020
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31907687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012
|full-text-url=https://sci-hub.do/10.1007/s10565-019-09503-6
|full-text-url=https://sci-hub.do/10.1002/mrd.23079
}}
}}
* {{medline-title
* {{medline-title
|title=Pevonedistat targeted therapy inhibits canine melanoma cell growth through induction of DNA re-replication and senescence.
|title=Effect of [[CCNB1]] silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer.
|date=09.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30069972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473101
|full-text-url=https://sci-hub.do/10.1002/jcp.26816
}}
}}
* {{medline-title
* {{medline-title
|title=Protein neddylation and its alterations in human cancers for targeted therapy.
|title=Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan.
|date=04.2018
|date=31.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29331584
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881094
}}
}}
==CCR5==
* {{medline-title
* {{medline-title
|title=Targeting protein neddylation with an [[NEDD8]]-activating enzyme inhibitor [[MLN]]4924 induced apoptosis or senescence in human lymphoma cells.
|title=[Enhancement can do harm].
|date=2015
|date=08-09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782162
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31532388
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623239
|full-text-url=https://sci-hub.do/10.1051/medsci/2019136
}}
}}
==NFE2L2==
* {{medline-title
* {{medline-title
|title=The double-edged sword of [[MTOR]] in autophagy deficiency induced-liver injury and tumorigenesis.
|title=[[CCR5]]-∆32 is deleterious in the homozygous state in humans.
|date=09.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31216956
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693464
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613792
}}
}}
* {{medline-title
* {{medline-title
|title=The Association of a Single-Nucleotide Polymorphism in the Nuclear Factor (Erythroid-Derived 2)-Like 2 Gene With Adverse Drug Reactions, Multimorbidity, and Frailty in Older People.
|title=[[CCR5]] chemokine receptor gene polymorphisms in ocular toxoplasmosis.
|date=22.05.2020
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102514
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29221851
|full-text-url=https://sci-hub.do/10.1093/gerona/glz131
|full-text-url=https://sci-hub.do/10.1016/j.actatropica.2017.12.012
}}
}}
==CD24==
* {{medline-title
* {{medline-title
|title=Immunohistochemical localization of Nrf2 in the human cochlea.
|title=[[CD24]] expression indicates healthier phenotype and less tendency of cellular senescence in human nucleus pulposus cells.
|date=01.12.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29981724
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31334674
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231984
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1642205
}}
}}
* {{medline-title
* {{medline-title
|title=Lifespan extension by peroxidase and dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in [i]C. elegans[/i].
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|date=01.08.2017
|date=05.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676501
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|full-text-url=https://sci-hub.do/10.1242/jcs.202119
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
}}
}}
* {{medline-title
* {{medline-title
|title=Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis.
|title=Some chemotherapeutics-treated colon cancer cells display a specific phenotype being a combination of stem-like and senescent cell features.
|date=02.11.2015
|date=02.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053388
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824610
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790359
}}
}}
==NOS3==
==CD81==


* {{medline-title
* {{medline-title
|title=Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation.
|title=Ovarian aging increases small extracellular vesicle [[CD81]]  release in human follicular fluid and influences miRNA profiles.
|date=22.05.2020
|date=17.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32455928
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290800
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343446
}}
}}
* {{medline-title
* {{medline-title
|title=Hypertension and longevity: role of genetic polymorphisms in renin-angiotensin-aldosterone system and endothelial nitric oxide synthase.
|title=Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature.
|date=05.2019
|date=15.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30460536
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32326435
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3470-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227017
}}
}}
* {{medline-title
* {{medline-title
|title=[[NOS3]] Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels.
|title=Increased production of functional small extracellular vesicles in senescent endothelial cells.
|date=11.07.2018
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891729
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32101370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041791
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176858
}}
}}
==CD9==
* {{medline-title
* {{medline-title
|title=Vascular senescence and ageing: a role for the MEOX proteins in promoting endothelial dysfunction.
|title=Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging.
|date=10.2017
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28727928
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220525
|full-text-url=https://sci-hub.do/10.1139/cjpp-2017-0149
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116582
}}
}}
* {{medline-title
* {{medline-title
|title=Fetal programming of blood pressure in a transgenic mouse model of altered intrauterine environment.
|title=Effects of RSC96 Schwann Cell-Derived Exosomes on Proliferation, Senescence, and Apoptosis of Dorsal Root Ganglion Cells In Vitro.
|date=01.12.2016
|date=02.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27506899
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30387453
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134377
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6228118
}}
}}
==NPR1==
* {{medline-title
* {{medline-title
|title=The [[NPR1]]-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana.
|title=Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice.
|date=03.12.2020
|date=28.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33270345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30265241
|full-text-url=https://sci-hub.do/10.1111/jipb.13044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167054
}}
}}
==CDC42==
* {{medline-title
* {{medline-title
|title=Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis.
|title=Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1.
|date=07.2020
|date=05.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32540002
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31487690
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2020.110472
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756888
}}
}}
* {{medline-title
* {{medline-title
|title=Some things get better with age: differences in salicylic acid accumulation and defense signaling in young and mature Arabidopsis.
|title=Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies.
|date=2014
|date=20.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25620972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30341976
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288333
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224233
}}
}}
* {{medline-title
* {{medline-title
|title=Mitogen-activated protein kinase 6 regulates [[NPR1]] gene expression and activation during leaf senescence induced by salicylic acid.
|title=The relationship between reproductive and biochemical ageing at the time of the menopausal transition.
|date=12.2014
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25210078
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28843511
|full-text-url=https://sci-hub.do/10.1093/jxb/eru369
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.028
}}
}}
==CDK5==
* {{medline-title
* {{medline-title
|title=Autophagy deficiency leads to accumulation of ubiquitinated proteins, ER stress, and cell death in Arabidopsis.
|title=Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence.
|date=09.2014
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25046116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31636448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206536
|full-text-url=https://sci-hub.do/10.1038/s41593-019-0505-1
}}
}}
==NRK==
* {{medline-title
* {{medline-title
|title=[Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/[[ULK1]] signaling activation].
|title=CK2 inhibition protects white matter from ischemic injury.
|date=03.2019
|date=20.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989992
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125643
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20181205.001
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.08.021
}}
}}
* {{medline-title
* {{medline-title
|title=Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-[[ULK1]] signaling-mediated autophagy.
|title=CK2 inhibition confers functional protection to young and aging axons against ischemia by differentially regulating the [[CDK5]] and AKT signaling pathways.
|date=24.12.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585174
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29944965
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326678
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2018.05.011
}}
}}
==COMP==
* {{medline-title
* {{medline-title
|title=Fascin2 regulates cisplatin-induced apoptosis in [[NRK]]-52E cells.
|title=Effect of circadian rhythm, age, training and acute lameness on serum concentrations of cartilage oligomeric matrix protein ([[COMP]]) neo-epitope in horses.
|date=15.01.2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27989596
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30739342
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074922
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767518
}}
}}
* {{medline-title
* {{medline-title
|title=2,3,5,4'-Tetrahydroxystilbene-2-O-[i]β[/i]-D-glucoside Promotes Expression of the Longevity Gene Klotho.
|title=Genetic overexpression of [[COMP]]-Ang1 impairs BM microenvironment and induces senescence of BM HSCs.
|date=2016
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27885332
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112329
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.210
}}
}}
* {{medline-title
* {{medline-title
|title=A role for the age-dependent loss of α(E)-catenin in regulation of N-cadherin expression and cell migration.
|title=Longitudinal Twin Study of Subjective Health: Differences in Genetic and Environmental Components of Variance Across Age and Sex.
|date=01.06.2014
|date=01.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24920123
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909438
}}
}}
==PIN1==
==CPT1C==


* {{medline-title
* {{medline-title
|title=Brain somatic mutations observed in Alzheimer's disease associated with aging and dysregulation of tau phosphorylation.
|title=Carnitine palmitoyltransferase 1C reverses cellular senescence of MRC-5 fibroblasts via regulating lipid accumulation and mitochondrial function.
|date=12.07.2019
|date=02.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31300647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32632982
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626023
|full-text-url=https://sci-hub.do/10.1002/jcp.29906
}}
* {{medline-title
|title=Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence.
|date=14.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32289751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202531
}}
}}
* {{medline-title
* {{medline-title
|title=Class XI Myosins Contribute to Auxin Response and Senescence-Induced Cell Death in [i]Arabidopsis[/i].
|title=Effects of carnitine palmitoyltransferases on cancer cellular senescence.
|date=2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30538710
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30070697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277483
|full-text-url=https://sci-hub.do/10.1002/jcp.27042
}}
}}
==CRY1==
* {{medline-title
* {{medline-title
|title=Effects of Melatonin and Its Underlying Mechanism on Ethanol-Stimulated Senescence and Osteoclastic Differentiation in Human Periodontal Ligament Cells and Cementoblasts.
|title=Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-[[CRY1]] Transgenic Mice.
|date=12.06.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29895782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31179341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032161
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507265
}}
}}
* {{medline-title
* {{medline-title
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|title=Investigating circadian clock gene expression in human tendon biopsies from acute exercise and immobilization studies.
|date=2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
|full-text-url=https://sci-hub.do/10.1007/s00421-019-04129-2
}}
}}
* {{medline-title
* {{medline-title
|title=Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=03.2017
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27612437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://sci-hub.do/10.1002/stem.2495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
==POLD1==
==CTCF==


* {{medline-title
* {{medline-title
|title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes.
|title=New targeted approaches for epigenetic age predictions.
|date=10.2019
|date=24.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32580727
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315536
}}
}}
* {{medline-title
* {{medline-title
|title=[[POLD1]] deficiency is involved in cognitive function impairment in AD patients and SAMP8 mice.
|title=Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty.
|date=06.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30978525
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765957
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2019.108833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938407
}}
}}
* {{medline-title
* {{medline-title
|title=[[E2F1]] mediates the downregulation of [[POLD1]] in replicative senescence.
|title=[[HMGB2]] Loss upon Senescence Entry Disrupts Genomic Organization and Induces [[CTCF]] Clustering across Cell Types.
|date=07.2019
|date=17.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30895337
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706538
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588650
|full-text-url=https://sci-hub.do/10.1016/j.molcel.2018.03.030
}}
}}
==CTH==
* {{medline-title
* {{medline-title
|title=Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing.
|title=Anterior Cingulate Structure and Perfusion is Associated with Cerebrospinal Fluid Tau among Cognitively Normal Older Adult APOEɛ4 Carriers.
|date=03.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29208544
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31743999
|full-text-url=https://sci-hub.do/10.1016/j.arr.2017.12.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310575
}}
}}
* {{medline-title
* {{medline-title
|title=[[POLD1]]: Central mediator of DNA replication and repair, and implication in cancer and other pathologies.
|title=Curious CXR.
|date=15.09.2016
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27320729
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31320335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969162
|full-text-url=https://sci-hub.do/10.1136/emermed-2019-208453
}}
}}
==PRMT1==
* {{medline-title
* {{medline-title
|title=Reactive oxygen species extend insect life span using components of the insulin-signaling pathway.
|title=Mechanochemical Catalytic Transfer Hydrogenation of Aromatic Nitro Derivatives.
|date=12.09.2017
|date=30.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847950
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30513686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604040
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321105
}}
}}
==CTNNB1==
* {{medline-title
* {{medline-title
|title=Regenerating muscle with arginine methylation.
|title=[i][[TP53]][/i] Tumor-suppressor Gene Plays a Key Role in [[IGF1]] Signaling Pathway Related to the Aging of Human Melanocytes.
|date=27.05.2017
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28301308
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501374
|full-text-url=https://sci-hub.do/10.21873/anticanres.13363
}}
}}
* {{medline-title
* {{medline-title
|title=Simultaneous ablation of prmt-1 and prmt-5 abolishes asymmetric and symmetric arginine dimethylations in Caenorhabditis elegans.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=01.06.2017
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28158808
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1093/jb/mvw101
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
* {{medline-title
* {{medline-title
|title=Caveolin1/protein arginine methyltransferase1/sirtuin1 axis as a potential target against endothelial dysfunction.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=05.2017
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28126510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1016/j.phrs.2017.01.022
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
* {{medline-title
==CTSB==
|title=Epigallocatechin-3-gallate ameliorates erectile function in aged rats via regulation of [[PRMT1]]/DDAH/ADMA/NOS metabolism pathway.
|date=05-06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27080477
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427783
}}
==PROC==


* {{medline-title
* {{medline-title
|title=Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation.
|title=Myocardial cathepsin D is downregulated in sudden cardiac death.
|date=15.04.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32176724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157190
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075574
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of feeding frequency of an elevated plane of milk replacer and calf age on behavior, and glucose and insulin kinetics in male Holstein calves.
|title=A Free Radical-Generating System Regulates Amyloid Oligomers: Involvement of Cathepsin B.
|date=07.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30419975
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400084
|full-text-url=https://sci-hub.do/10.1017/S175173111800294X
|full-text-url=https://sci-hub.do/10.3233/JAD-170159
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related effects on markers of inflammation and cartilage metabolism in response to an intra-articular lipopolysaccharide challenge in horses.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=02.2017
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28380609
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://sci-hub.do/10.2527/jas.2016.1078
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==CYP2J2==
* {{medline-title
* {{medline-title
|title=Normative data for rotational chair stratified by age.
|title=The effects of endothelium-specific [[CYP2J2]] overexpression on the attenuation of retinal ganglion cell apoptosis in a glaucoma rat model.
|date=02.2016
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26227880
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31295013
|full-text-url=https://sci-hub.do/10.1002/lary.25497
|full-text-url=https://sci-hub.do/10.1096/fj.201900756R
}}
}}
* {{medline-title
* {{medline-title
|title=Day-to-Day Impact of Vaginal Aging questionnaire: a multidimensional measure of the impact of vaginal symptoms on functioning and well-being in postmenopausal women.
|title=Regional vulnerability to lipoxidative damage and inflammation in normal human brain aging.
|date=02.2015
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24983271
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30077575
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280352
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.023
}}
}}
==PTS==
* {{medline-title
* {{medline-title
|title=Posttraumatic stress symptom persistence across 24 years: association with brain structures.
|title=Endothelium-specific [[CYP2J2]] overexpression attenuates age-related insulin resistance.
|date=08.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30830577
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29318723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722032
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847864
}}
}}
==DCT==
* {{medline-title
* {{medline-title
|title=Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis.
|title=Changes in expression of special AT-rich sequence binding protein 1 and phosphatase and tensin homologue in kidneys of diabetic rats during ageing.
|date=18.07.2018
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29506055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052528
|full-text-url=https://sci-hub.do/10.1093/ndt/gfy003
}}
}}
* {{medline-title
* {{medline-title
|title=Post-traumatic stress syndrome in a large sample of older adults: determinants and quality of life.
|title=Evaluation of the NAL Dynamic Conversations Test in older listeners with hearing loss.
|date=2016
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25803227
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28826285
|full-text-url=https://sci-hub.do/10.1080/13607863.2015.1018864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114171
}}
}}
* {{medline-title
* {{medline-title
|title=Continuous exposure to life threats among different age groups in different types of communities.
|title=Dihydrocapsiate improved age-associated impairments in mice by increasing energy expenditure.
|date=05.2015
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25793400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28811294
|full-text-url=https://sci-hub.do/10.1037/a0038772
|full-text-url=https://sci-hub.do/10.1152/ajpendo.00132.2017
}}
}}
==DDC==
* {{medline-title
* {{medline-title
|title=Post-traumatic stress symptoms and adult attachment: a 24-year longitudinal study.
|title=N-Acetyl Cysteine Attenuates the Sarcopenia and Muscle Apoptosis Induced by Chronic Liver Disease.
|date=12.2014
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24636844
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31530262
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138283
|full-text-url=https://sci-hub.do/10.2174/1566524019666190917124636
}}
}}
==PTX3==
* {{medline-title
* {{medline-title
|title=Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects.
|title=Aging-Related Expression of Twinfilin-1 Regulates Cholangiocyte Biological Response to Injury.
|date=27.01.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012711
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30561764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070734
|full-text-url=https://sci-hub.do/10.1002/hep.30466
}}
}}
* {{medline-title
* {{medline-title
|title=Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study.
|title=Life History of Parthenolecanium spp. (Hemiptera: Coccidae) in Urban Landscapes of the Southeastern United States.
|date=13.07.2020
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31808814
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357589
|full-text-url=https://sci-hub.do/10.1093/jee/tox170
}}
}}
==DDO==
* {{medline-title
* {{medline-title
|title=Inflammatory Long Pentraxin 3 is Associated with Leukocyte Telomere Length in Night-Shift Workers.
|title=New insights on the influence of free d-aspartate metabolism in the mammalian brain during prenatal and postnatal life.
|date=2017
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28536575
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32561430
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422482
|full-text-url=https://sci-hub.do/10.1016/j.bbapap.2020.140471
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent cellular reactions of the human immune system of humanized NOD scid gamma mice on LPS stimulus.
|title=Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity.
|date=04.2017
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28162006
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822420
|full-text-url=https://sci-hub.do/10.1177/1753425917690814
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2019.02.014
}}
}}
* {{medline-title
* {{medline-title
|title=Elevated pentraxin 3 level at the early stage of exercise training is associated with reduction of arterial stiffness in middle-aged and older adults.
|title=Secreted d-aspartate oxidase functions in C. elegans reproduction and development.
|date=09.2016
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26467819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30387556
|full-text-url=https://sci-hub.do/10.1038/jhh.2015.105
|full-text-url=https://sci-hub.do/10.1111/febs.14691
}}
}}
==PYY==
==DKK1==


* {{medline-title
* {{medline-title
|title=Peptide YY ([[PYY]]) Is Expressed in Human Skeletal Muscle Tissue and Expanding Human Muscle Progenitor Cells.
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women.
|date=2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448
}}
}}
* {{medline-title
* {{medline-title
|title=Peptide YY induces characteristic meal patterns of aged mice.
|title=Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling.
|date=11.2017
|date=11.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28916138
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080114
|full-text-url=https://sci-hub.do/10.1016/j.yhbeh.2017.09.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565990
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of randomized whey-protein loads on energy intake, appetite, gastric emptying, and plasma gut-hormone concentrations in older men and women.
|title=[Role and alterations of DNA methylation during the aging and cancer].
|date=09.2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28747330
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|full-text-url=https://sci-hub.do/10.3945/ajcn.117.154377
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
}}
}}
==DLD==
* {{medline-title
* {{medline-title
|title=Glucagon-like peptide-1 (GLP-1) increases in plasma and colon tissue prior to estrus and circulating levels change with increasing age in reproductively competent Wistar rats.
|title=A preliminary study of cerebral blood flow, aging and dementia in people with Down syndrome.
|date=04.2017
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28237410
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32996650
|full-text-url=https://sci-hub.do/10.1016/j.peptides.2017.02.010
|full-text-url=https://sci-hub.do/10.1111/jir.12784
}}
}}
* {{medline-title
* {{medline-title
|title=Increased peptide YY blood concentrations, not decreased acyl-ghrelin, are associated with reduced hunger and food intake in healthy older women: Preliminary evidence.
|title=Premature senescence activation in [[DLD]]-1 colorectal cancer cells through adjuvant therapy to induce a miRNA profile modulating cellular death.
|date=01.10.2016
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27264721
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116375
|full-text-url=https://sci-hub.do/10.1016/j.appet.2016.06.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090263
}}
}}
==RACK1==
* {{medline-title
* {{medline-title
|title=Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging.
|title=Immature Auditory Evoked Potentials in Children With Moderate-Severe Developmental Language Disorder.
|date=05.11.2019
|date=13.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31636180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29974119
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842600
|full-text-url=https://sci-hub.do/10.1044/2018_JSLHR-L-17-0420
}}
}}
==DNMT3B==
* {{medline-title
* {{medline-title
|title=Role of Hormones in the Regulation of [[RACK1]] Expression as a Signaling Checkpoint in Immunosenescence.
|title=Alcohol Extracts From [i]Ganoderma lucidum[/i] Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents.
|date=06.07.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28684670
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971923
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444160
}}
}}
* {{medline-title
* {{medline-title
|title=Transcriptional regulation of [[RACK1]] and modulation of its expression: Role of steroid hormones and significance in health and aging.
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|date=07.2017
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28192162
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2017.02.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
}}
}}
* {{medline-title
* {{medline-title
|title=Role of androgens in dhea-induced rack1 expression and cytokine modulation in monocytes.
|title=Effects of Parental Aging During Embryo Development and Adult Life: The Case of Nothobranchius furzeri.
|date=2016
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27239218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304310
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884617
|full-text-url=https://sci-hub.do/10.1089/zeb.2017.1494
}}
}}
* {{medline-title
==EP300==
|title=Immunostimulatory effects of [[RACK1]] pseudosubstrate in human leukocytes obtained from young and old donors.
|date=30.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25779661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466631
}}
==RB1==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=15.11.2017
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
* {{medline-title
* {{medline-title
|title=Mesenchymal stromal cells having inactivated [[RB1]] survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy.
|title=Aspirin-another caloric-restriction mimetic.
|date=02.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27124644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29929449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103658
}}
}}
* {{medline-title
* {{medline-title
|title=Suppression of [[RAD21]] Induces Senescence of MDA-[[MB]]-231 Human Breast Cancer Cells Through [[RB1]] Pathway Activation Via c-Myc Downregulation.
|title=Aspirin Recapitulates Features of Caloric Restriction.
|date=06.2016
|date=27.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26529363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29490275
|full-text-url=https://sci-hub.do/10.1002/jcb.25426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848858
}}
* {{medline-title
|title=Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824446
|full-text-url=https://sci-hub.do/10.1136/bjsports-2014-094073
}}
}}
==FABP3==
* {{medline-title
* {{medline-title
|title=[[RB1]]-mediated cell-autonomous and host-dependent oncosuppressor mechanisms in radiation-induced osteosarcoma.
|title=[[FABP3]]-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging.
|date=01.01.2014
|date=09.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24800165
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168829
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653047
}}
}}
==REN==
* {{medline-title
* {{medline-title
|title=The Hispanic Paradox: Race/Ethnicity and Nativity, Immigrant Enclave Residence and Cognitive Impairment Among Older US Adults.
|title=Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing [[FABP3]].
|date=05.2017
|date=04.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28369694
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143524
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435528
|full-text-url=https://sci-hub.do/10.1080/15548627.2020.1839286
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of Clinical Features and Outcomes of Skull Base Chordoma in Different Age-Groups.
|title=Myokines as biomarkers of frailty and cardiovascular disease risk in females.
|date=08.2016
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27237421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32017952
|full-text-url=https://sci-hub.do/10.1016/j.wneu.2016.05.035
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110859
}}
}}
==FIS1==
* {{medline-title
* {{medline-title
|title=ASSOCIATION OF PREVASCUL[[AR]] [[VIT]]REOUS FISSURES AND CISTERNS WI[[TH]] [[VIT]]REOUS DEGENERATION AS ASSESSED BY SWEPT SOURCE OPTICAL COHE[[REN]]CE TO[[MOG]]RAPHY.
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.
|date=09.2015
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25874366
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555
|full-text-url=https://sci-hub.do/10.1097/IAE.0000000000000540
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of advanced age and renal dysfunction on the single- and repeated-dose pharmacokinetics of modified-release flupirtine.
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.
|date=03.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25613539
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614
|full-text-url=https://sci-hub.do/10.5414/CP202236
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
}}
}}
* {{medline-title
* {{medline-title
|title=Mapping nutrient resorption efficiencies of subarctic cryptogams and seed plants onto the Tree of Life.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=06.2014
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25360262
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201435
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==RHO==
==FOS==


* {{medline-title
* {{medline-title
|title=Conditional reprogramming: next generation cell culture.
|title=Muscle atrophy-related myotube-derived exosomal microRNA in neuronal dysfunction: Targeting both coding and long noncoding RNAs.
|date=08.2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32963937
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32233025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488362
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253071
}}
}}
* {{medline-title
* {{medline-title
|title=SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells.
|title=Dietary Fructooligosaccharide and Glucomannan Alter Gut Microbiota and Improve Bone Metabolism in Senescence-Accelerated Mouse.
|date=18.05.2020
|date=23.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32246845
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30632742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232010
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.8b05164
}}
}}
* {{medline-title
* {{medline-title
|title=Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=28.09.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30274229
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210377
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==FOXP1==
* {{medline-title
* {{medline-title
|title=NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through [i]memo-1[/i] in [i]C. elegans[/i].
|title=GATA6 regulates aging of human mesenchymal stem/stromal cells.
|date=13.01.2017
|date=30.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28085666
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33252174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235354
|full-text-url=https://sci-hub.do/10.1002/stem.3297
}}
}}
* {{medline-title
* {{medline-title
|title=Guanine nucleotide exchange factor OSG-1 confers functional aging via dysregulated Rho signaling in Caenorhabditis elegans neurons.
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.
|date=02.2015
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25527286
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317656
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247
}}
}}
==RICTOR==
* {{medline-title
* {{medline-title
|title=Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase.
|title=Downregulation of [[FOXP1]] correlates with tendon stem/progenitor cells aging.
|date=11.2019
|date=26.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31476350
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30170733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059097
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.136
}}
}}
==FYN==
* {{medline-title
* {{medline-title
|title=The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging.
|title=An inhibitor role of Nrf2 in the regulation of myocardial senescence and dysfunction after myocardial infarction.
|date=16.08.2016
|date=15.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27486771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32781064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288141
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118199
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=04.2015
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25751060
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396470
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
* {{medline-title
* {{medline-title
|title=Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan.
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|date=10.2014
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25059582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172536
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
}}
}}
==GBA==
* {{medline-title
* {{medline-title
|title=Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry.
|title=Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease.
|date=02.2015
|date=08.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589862
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31703585
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366598
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842240
}}
}}
==RIPK3==
* {{medline-title
* {{medline-title
|title=Metformin mediates cardioprotection against aging-induced ischemic necroptosis.
|title=Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain.
|date=02.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31944526
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29735433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996959
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015735
}}
}}
* {{medline-title
* {{medline-title
|title=A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice.
|title=[[GBA]] mutations in Parkinson disease: earlier death but similar neuropathological features.
|date=12.03.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862818
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28834018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657539
}}
}}
==GCLC==
* {{medline-title
* {{medline-title
|title=RIP kinases as modulators of inflammation and immunity.
|title=Aerobic exercise training partially reverses the impairment of Nrf2 activation in older humans.
|date=09.2018
|date=20.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32866619
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704731
}}
}}
* {{medline-title
* {{medline-title
|title=Necroptosis increases with age and is reduced by dietary restriction.
|title=Ontogeny and aging of Nrf2 pathway genes in livers of rats.
|date=08.2018
|date=15.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696779
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29689272
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052392
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2018.04.018
}}
}}
* {{medline-title
* {{medline-title
|title=[[RIPK1]]-[[RIPK3]]-[[MLKL]]-dependent necrosis promotes the aging of mouse male reproductive system.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=15.08.2017
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807105
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557593
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==S100A8==
==GEM==


* {{medline-title
* {{medline-title
|title=[[S100A8]], which increases with age, induces cellular senescence-like changes in bovine oviduct epithelial cells.
|title=The Impact of Geriatric Emergency Management Nurses on the Care of Frail Older Patients in the Emergency Department: a Systematic Review.
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32904804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458600
}}
* {{medline-title
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|date=09.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237976
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|full-text-url=https://sci-hub.do/10.1111/aji.13163
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
}}
}}
* {{medline-title
* {{medline-title
|title=Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model.
|title=Understanding of diagnosis and medications among non-English-speaking older patients.
|date=06.07.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991479
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377482
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078409
|full-text-url=https://sci-hub.do/10.1111/ajag.12503
}}
}}
==GPI==
* {{medline-title
* {{medline-title
|title=Lung cellular senescence is independent of aging in a mouse model of COPD/emphysema.
|title=Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain.
|date=13.06.2018
|date=10.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29899396
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32646997
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998122
|full-text-url=https://sci-hub.do/10.1126/science.aaw2622
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent changes in inflammation and extracellular matrix in bovine oviduct epithelial cells during the post-ovulatory phase.
|title=Potential role of exercise-induced glucose-6-phosphate isomerase in skeletal muscle function.
|date=09.2016
|date=30.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27580129
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31337203
|full-text-url=https://sci-hub.do/10.1002/mrd.22693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651688
}}
}}
* {{medline-title
* {{medline-title
|title=A transcriptional roadmap to the senescence and differentiation of human oral keratinocytes.
|title=Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria.
|date=01.2015
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24398559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156458
|full-text-url=https://sci-hub.do/10.1093/gerona/glt212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529780
}}
}}
==SCT==
==GPX1==


* {{medline-title
* {{medline-title
|title=Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults.
|title=Glutathione peroxidase-1 overexpression reduces oxidative stress, and improves pathology and proteome remodeling in the kidneys of old mice.
|date=10.2019
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32400101
|full-text-url=https://sci-hub.do/10.1519/JSC.0000000000002536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294784
}}
}}
* {{medline-title
* {{medline-title
|title=High-intensity interval training improves acute plasma volume responses to exercise that is age dependent.
|title=Effect of β-D-Mannuronic Acid (M2000) on Oxidative Stress Enzymes' Gene Using Healthy Donor Peripheral Blood Mononuclear Cells for Evaluating the Anti-Aging Property.
|date=02.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29464883
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29766814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820462
|full-text-url=https://sci-hub.do/10.2174/1570163815666180515122834
}}
}}
* {{medline-title
* {{medline-title
|title=Communication technology adoption among older adult veterans: the interplay of social and cognitive factors.
|title=The impact of preserved Klotho gene expression on antioxidative stress activity in healthy kidney.
|date=12.2018
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29019416
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29693450
|full-text-url=https://sci-hub.do/10.1080/13607863.2017.1381946
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00486.2017
}}
==GPX4==
 
* {{medline-title
|title=l-carnitine supplementation during in vitro culture regulates oxidative stress in embryos from bovine aged oocytes.
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31837632
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2019.11.036
}}
}}
* {{medline-title
* {{medline-title
|title=Repeatability of Choroidal Thickness Measurements on Enhanced Depth Imaging Optical Coherence Tomography Using Different Posterior Boundaries.
|title=Dietary Selenium Supplementation Ameliorates Female Reproductive Efficiency in Aging Mice.
|date=09.2016
|date=11.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27345731
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31835711
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687829
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969897
}}
}}
* {{medline-title
* {{medline-title
|title=HIV cure strategies: how good must they be to improve on current antiretroviral therapy?
|title=Resveratrol improves in vitro maturation of oocytes in aged mice and humans.
|date=2014
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25397616
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232561
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.01.020
}}
}}
==SET==
==GSS==


* {{medline-title
* {{medline-title
|title=Chromatin Modifiers [[SET]]-25 and [[SET]]-32 Are Required for Establishment but Not Long-Term Maintenance of Transgenerational Epigenetic Inheritance.
|title=Geriatric brain tumor management part I: Meningioma.
|date=20.11.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208835
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.10.085
|full-text-url=https://sci-hub.do/10.1016/j.jocn.2019.05.063
}}
}}
* {{medline-title
* {{medline-title
|title=[[SET]]-9 and [[SET]]-26 are H3K4me3 readers and play critical roles in germline development and longevity.
|title=Link between cardiac function and the antioxidative defense mechanism in aged rats.
|date=01.05.2018
|date=11.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29714684
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31010674
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010342
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.03.182
}}
}}
* {{medline-title
* {{medline-title
|title=Muscle-Specific Histone H3K36 Dimethyltransferase [[SET]]-18 Shortens Lifespan of Caenorhabditis elegans by Repressing daf-16a Expression.
|title=Towards improving sterile insect technique: Exposure to orange oil compounds increases sexual signalling and longevity in Ceratitis capitata males of the Vienna 8 [[GSS]].
|date=06.03.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29514099
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29190755
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.02.029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708806
}}
}}
==GSTM1==
* {{medline-title
* {{medline-title
|title=Assessing efficacy of day 3 embryo time-lapse algorithms retrospectively: impacts of dataset type and confounding factors.
|title=The effects of everyday-life exposure to polycyclic aromatic hydrocarbons on biological age indicators.
|date=09.2019
|date=03.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338469
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33272294
|full-text-url=https://sci-hub.do/10.1080/14647273.2018.1425919
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713168
}}
}}
* {{medline-title
* {{medline-title
|title=CONSTANCES: a general prospective population-based cohort for occupational and environmental epidemiology: cohort profile.
|title=Carrying the T Allele of the SNP rs574344, an eQTL of [[GSTM1]], Contributes to Longevity in the Han Chinese Population.
|date=01.2017
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27884936
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30589570
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241503
|full-text-url=https://sci-hub.do/10.1089/gtmb.2018.0178
}}
}}
==SMAD4==
* {{medline-title
* {{medline-title
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=09.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==HDAC4==
* {{medline-title
* {{medline-title
|title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16  and Wild-Type p53.
|title=The posttranslational modification of [[HDAC4]] in cell biology: Mechanisms and potential targets.
|date=2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31588631
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985
|full-text-url=https://sci-hub.do/10.1002/jcb.29365
}}
}}
* {{medline-title
* {{medline-title
|title=iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation.
|title=Exercise preconditioning attenuates hind limb unloading-induced gastrocnemius muscle atrophy possibly via the [[HDAC4]]/Gadd45 axis in old rats.
|date=01.10.2017
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708522
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009659
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.06.014
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.04.010
}}
}}
* {{medline-title
* {{medline-title
|title=miR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4.
|title=Novel anti-aging gene NM_026333 contributes to proton-induced aging via NCX1-pathway.
|date=01.08.2015
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26215566
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30385152
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536309
|full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2018.10.021
}}
}}
* {{medline-title
==HFE==
|title=Loss of smad4 in Sertoli and Leydig cells leads to testicular dysgenesis and hemorrhagic tumor formation in mice.
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24501173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076392
}}
==SMS==


* {{medline-title
* {{medline-title
|title=Does a Live Performance Impact Synchronization to Musical Rhythm in Cognitively Impaired Elderly?
|title=Polyphenol Characterization and Skin-Preserving Properties of Hydroalcoholic Flower Extract from [i]Himantoglossum robertianum[/i] (Orchidaceae).
|date=2020
|date=14.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33104027
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31739534
|full-text-url=https://sci-hub.do/10.3233/JAD-200521
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918203
}}
}}
* {{medline-title
* {{medline-title
|title=Testing the effectiveness of physical activity advice delivered via text messaging vs. human phone advisors in a Latino population: The On The Move randomized controlled trial design and methods.
|title=Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-[[F10]] cells by inducing senescence.
|date=08.2020
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351675
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.06.008
}}
}}
* {{medline-title
* {{medline-title
|title=Mobile Health Interventions for Physical Activity, Sedentary Behavior, and Sleep in Adults Aged 50 Years and Older: A Systematic Literature Review.
|title=Iron-processing genotypes, nutrient intakes, and cadmium levels in the Normative Aging Study: Evidence of sensitive subpopulations in cadmium risk assessment.
|date=01.08.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30507266
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30059941
|full-text-url=https://sci-hub.do/10.1123/japa.2017-0410
|full-text-url=https://sci-hub.do/10.1016/j.envint.2018.06.040
}}
}}
==HMGA2==
* {{medline-title
* {{medline-title
|title=Senescence-messaging secretome factors trigger premature senescence in human endometrium-derived stem cells.
|title=4D Genome Rewiring during Oncogene-Induced and Replicative Senescence.
|date=19.02.2018
|date=07.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32220303
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208559
}}
}}
* {{medline-title
* {{medline-title
|title=PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.
|title=The protective effects of [[HMGA2]] in the senescence process of bone marrow-derived mesenchymal stromal cells.
|date=13.05.2014
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24778222
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32068957
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024885
|full-text-url=https://sci-hub.do/10.1002/term.3023
}}
}}
==SNAP25==
* {{medline-title
* {{medline-title
|title=The Biological Foundations of Sarcopenia: Established and Promising Markers.
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
|date=05.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005
}}
==HSPA8==
 
* {{medline-title
|title=Influence of Normal Aging on Brain Autophagy: A Complex Scenario.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31457015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30914945
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700259
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421305
}}
* {{medline-title
|title=Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone [[HSPA8]] and the ubiquitin ligase UBE2D.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30368041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202877
}}
}}
* {{medline-title
* {{medline-title
|title=Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age.
|title=Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging.
|date=06.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29496544
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29867441
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952035
}}
}}
==ICOS==
* {{medline-title
* {{medline-title
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells.
|title=The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30560130
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287204
}}
}}
* {{medline-title
* {{medline-title
|title=Global hypoxia induced impairment in learning and spatial memory is associated with precocious hippocampal aging.
|title=End-stage renal disease, dialysis, kidney transplantation and their impact on [[CD4]]  T-cell differentiation.
|date=09.2016
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27246251
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29722011
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2016.05.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142287
}}
}}
* {{medline-title
* {{medline-title
|title=[[NOS1]] and [[SNAP25]] polymorphisms are associated with Attention-Deficit/Hyperactivity Disorder symptoms in adults but not in children.
|title=Characterization of Blimp-1 function in effector regulatory T cells.
|date=04.2016
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26821215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29724515
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2016.01.010
|full-text-url=https://sci-hub.do/10.1016/j.jaut.2018.04.003
}}
}}
==SOCS1==
==IGFBP5==


* {{medline-title
* {{medline-title
|title=Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus.
|title=Intracellular Heat Shock Protein 70 Deficiency in Pulmonary Fibrosis.
|date=06.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30656452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30543447
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0607-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543745
}}
}}
* {{medline-title
* {{medline-title
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|title=Blunted satellite cell response is associated with dysregulated IGF-1 expression after exercise with age.
|date=28.10.2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30062517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
|full-text-url=https://sci-hub.do/10.1007/s00421-018-3954-4
}}
}}
* {{medline-title
* {{medline-title
|title=Daily Socs1 rhythms alter with aging differentially in peripheral clocks in male Wistar rats: therapeutic effects of melatonin.
|title=Material-induced Senescence (MIS): Fluidity Induces Senescent Type Cell Death of Lung Cancer Cells via Insulin-Like Growth Factor Binding Protein 5.
|date=06.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28331994
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29187894
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9687-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706090
}}
}}
==IL2==
* {{medline-title
* {{medline-title
|title=Differential response to intrahippocampal interleukin-4/interleukin-13 in aged and exercise mice.
|title=Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus.
|date=20.02.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27916728
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33193368
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800496
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662090
}}
}}
* {{medline-title
* {{medline-title
|title=Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4  T cells in aged rats.
|title=Redox, immune and genetic biomarker system for personalized treatments in colorectal cancer.
|date=2015
|date=15.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448779
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30788039
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596406
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379753
}}
}}
==TAT==
* {{medline-title
* {{medline-title
|title=Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides.
|title=Low IL-2 Expressing T Cells in Thalassemia Major Patients: Is It Immune Aging.
|date=2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31024341
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30369736
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467974
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186253
}}
}}
==ILK==
* {{medline-title
* {{medline-title
|title=Effects of HIV-1 gp120 and [[TAT]]-derived microvesicles on endothelial cell function.
|title=Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy.
|date=01.05.2019
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789287
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30605403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485685
}}
}}
* {{medline-title
* {{medline-title
|title=Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation.
|title=Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia.
|date=05.01.2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28055018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30271655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386354
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147593
}}
}}
* {{medline-title
* {{medline-title
|title=Characteristics, tissue-specific expression, and hormonal regulation of expression of tyrosine aminotransferase in the avian female reproductive tract.
|title=Integrin-linked kinase: A new actor in the ageing process?
|date=10.2016
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27295280
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101014
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2016.05.001
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.10.026
}}
}}
* {{medline-title
==IPP==
|title=Nanog induces suppression of senescence through downregulation of p27KIP1 expression.
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26795560
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813312
}}
==TCF7L2==


* {{medline-title
* {{medline-title
|title=A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder.
|title=Toxic effect of the novel chiral insecticide [[IPP]] and its biodegradation intermediate in nematode Caenorhabditis elegans.
|date=03.2020
|date=30.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32015540
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30153642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065955
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.08.059
}}
}}
* {{medline-title
* {{medline-title
|title=Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle.
|title=The inositol pyrophosphate pathway in health and diseases.
|date=01.03.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30824849
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29282838
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383672
}}
}}
* {{medline-title
* {{medline-title
|title=[[TCF7L1]] promotes skin tumorigenesis independently of β-catenin through induction of [[LCN2]].
|title=Integrin-linked kinase: A new actor in the ageing process?
|date=03.05.2017
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28467300
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438253
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.10.026
}}
}}
* {{medline-title
==IRF8==
|title=[Frequency of some diseases and conditions in geriatric patients with coronary heart disease and various genotypes of transcription factor 7-like 2 protein].
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25946847


}}
* {{medline-title
* {{medline-title
|title=Aging and cardiovascular diseases: the role of gene-diet interactions.
|title=[[IRF8]] induces senescence of lung cancer cells to exert its tumor suppressive function.
|date=11.2014
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25159268
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31594449
|full-text-url=https://sci-hub.do/10.1016/j.arr.2014.08.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927690
}}
}}
==TLR1==
* {{medline-title
* {{medline-title
|title=Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=01.12.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32969782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00615.2020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
* {{medline-title
* {{medline-title
|title=Association of TLR gene variants in a Czech Red Pied cattle population with reproductive traits.
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes.
|date=02.2020
|date=12.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31901560
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2019.109997
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941
}}
}}
==KIN==
* {{medline-title
* {{medline-title
|title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.
|title=The noncanonical small heat shock protein HSP-17 from [i]Caenorhabditis elegans[/i] is a selective protein aggregase.
|date=05.2018
|date=06.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32001616
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062175
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in the expression of the Toll-like receptor system in the aging rat kidneys.
|title=[[KIN]]-4/MAST kinase promotes [[PTEN]]-mediated longevity of Caenorhabditis elegans via binding through a PDZ domain.
|date=2014
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30773781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014502
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516182
}}
}}
* {{medline-title
* {{medline-title
|title=Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging.
|title=Adenine type and diphenyl urea derived cytokinins improve the postharvest performance of [i]Iris germanica[/i] L. cut scapes.
|date=02.2014
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24595889
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30425429
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969281
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214446
}}
}}
==TRPA1==
==KLRG1==


* {{medline-title
* {{medline-title
|title=Important regulatory function of transient receptor potential ankyrin 1 receptors in age-related learning and memory alterations of mice.
|title=Are skin senescence and immunosenescence linked within individuals?
|date=10.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327098
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31062498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612632
}}
}}
* {{medline-title
* {{medline-title
|title=Aging of mouse intervertebral disc and association with back pain.
|title=Increased T cell immunosenescence and accelerated maturation phenotypes in older kidney transplant recipients.
|date=06.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30936040
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29913200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429965
}}
}}
* {{medline-title
* {{medline-title
|title=Congeneric variability in lifespan extension and onset of senescence suggest active regulation of aging in response to low temperature.
|title=Impact of Aging on the Frequency, Phenotype, and Function of CD161-Expressing T Cells.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399408
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29725326
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336457
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917671
}}
}}
==LAMP1==
* {{medline-title
* {{medline-title
|title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases.
|title=Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain.
|date=02.2018
|date=24.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32579115
|full-text-url=https://sci-hub.do/10.1111/nmo.13185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367682
}}
}}
* {{medline-title
* {{medline-title
|title=A Caenorhabditis elegans Model Elucidates a Conserved Role for [[TRPA1]]-Nrf Signaling in Reactive α-Dicarbonyl Detoxification.
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|date=21.11.2016
|date=07.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27773573
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
}}
}}
==TRPM8==
* {{medline-title
* {{medline-title
|title=Morphological and functional changes in [[TRPM8]]-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice.
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|date=01.08.2018
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29664111
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|full-text-url=https://sci-hub.do/10.1002/cne.24454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
}}
}}
==LPL==
* {{medline-title
* {{medline-title
|title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases.
|title=Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects.
|date=02.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32684467
|full-text-url=https://sci-hub.do/10.1111/nmo.13185
|full-text-url=https://sci-hub.do/10.3168/jds.2020-18174
}}
}}
* {{medline-title
* {{medline-title
|title=Roles of [[TRPM8]] Ion Channels in Cancer: Proliferation, Survival, and Invasion.
|title=Influence of common health disorders on the length of productive life and stayability in German Holstein cows.
|date=23.10.2015
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26512697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31677834
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695882
|full-text-url=https://sci-hub.do/10.3168/jds.2019-16985
}}
}}
* {{medline-title
* {{medline-title
|title=Function and postnatal changes of dural afferent fibers expressing [[TRPM8]] channels.
|title=GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling.
|date=26.06.2015
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26111800
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29694926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480580
|full-text-url=https://sci-hub.do/10.1016/j.bone.2018.04.014
}}
}}
* {{medline-title
==LSS==
|title=Induction of oxidative stress causes functional alterations in mouse urothelium via a [[TRPM8]]-mediated mechanism: implications for aging.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24593692
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326884
}}
==UCP3==


* {{medline-title
* {{medline-title
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats.
|title=Surgical results in older patients with lumbar spinal stenosis according to gait speed in relation to the diagnosis for sarcopenia.
|date=01.2018
|date=01-04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32329390
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001
|full-text-url=https://sci-hub.do/10.1177/2309499020918422
}}
}}
* {{medline-title
* {{medline-title
|title=Pleiotropic effects of [[UCP2]]-[[UCP3]] variability on leucocyte telomere length and glucose homeostasis.
|title=Streamlining an existing hip fracture patient pathway in an acute tertiary adult Irish hospital to improve patient experience and outcomes.
|date=06.2017
|date=22.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28281015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31867664
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9690-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926383
}}
}}
* {{medline-title
* {{medline-title
|title=Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes [[UCP2]] and [[UCP3]] affect mitochondrial metabolism and healthy aging in female nonagenarians.
|title=Low-dose radiation from A-bombs elongated lifespan and reduced cancer mortality relative to un-irradiated individuals.
|date=08.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26965008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30598710
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935613
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299535
}}
}}
==MAPK1==
* {{medline-title
* {{medline-title
|title=[Genotype and allele frequencies of U[[CP]] and PP[[AR]] gene families in residents of besieged Leningrad and in the control group].
|title=Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1.
|date=2014
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850814
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413062
}}
}}
* {{medline-title
* {{medline-title
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=04.2014
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
==VCP==
* {{medline-title
* {{medline-title
|title=The role of air pollution and lung function in cognitive impairment.
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=02.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467204
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://sci-hub.do/10.1183/13993003.01963-2017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
}}
* {{medline-title
==MEF2A==
|title=Better parameters of ventilation-CO₂output relationship predict death in CHF patients.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27215018


}}
* {{medline-title
* {{medline-title
|title=Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal.
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|date=22.03.2016
|date=10.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27000202
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802725
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
}}
}}
* {{medline-title
* {{medline-title
|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|date=24.02.2016
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
}}
}}
* {{medline-title
* {{medline-title
|title=Characterization of C-terminal adaptors, UFD-2 and UFD-3, of CDC-48 on the polyglutamine aggregation in C. elegans.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=27.03.2015
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25721663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.02.088
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
==VDAC1==
==MGA==


* {{medline-title
* {{medline-title
|title=Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and [[VDAC1]] predicts mammalian longevity.
|title=Fatigue at baseline is associated with geriatric impairments and represents an adverse prognostic factor in older patients with a hematological malignancy.
|date=07.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32353747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054708
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191849
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182757
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in the expression of oxidative phosphorylation complexes in the aging intestinal mucosa.
|title=Geriatric assessment in oncology: Moving the concept forward. The 20 years of experience of the Centre Léon Bérard geriatric oncology program.
|date=01.07.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32173460
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29866469
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110924
|full-text-url=https://sci-hub.do/10.1016/j.jgo.2018.05.008
}}
}}
* {{medline-title
* {{medline-title
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|title=Degree of Peripheral Thyroxin Deiodination, Frailty, and Long-Term Survival in Hospitalized Older Patients.
|date=09.2019
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546287
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
|full-text-url=https://sci-hub.do/10.1210/jc.2017-02149
}}
}}
==MLKL==
* {{medline-title
* {{medline-title
|title=The Immp2l mutation causes age-dependent degeneration of cerebellar granule neurons prevented by antioxidant treatment.
|title=Remifentanil preconditioning protects against hypoxia-induced senescence and necroptosis in human cardiac myocytes [i]in vitro[/i].
|date=02.2016
|date=25.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26616244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32584786
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425462
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats.
|title=Necroptosis increases with age and is reduced by dietary restriction.
|date=07.2015
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25910621
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696779
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854160
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052392
}}
}}
==WAS==
* {{medline-title
* {{medline-title
|title=Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number.
|title=[[RIPK1]]-[[RIPK3]]-[[MLKL]]-dependent necrosis promotes the aging of mouse male reproductive system.
|date=09.11.2017
|date=15.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129830
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807105
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557593
}}
}}
==MLN==
* {{medline-title
* {{medline-title
|title=Measuring Work Ability with Its Antecedents: Evaluation of the Work Ability Survey.
|title=Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.
|date=06.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28741256
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849526
|full-text-url=https://sci-hub.do/10.1007/s10926-017-9720-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432217
}}
}}
* {{medline-title
* {{medline-title
|title=CONSTANCES: a general prospective population-based cohort for occupational and environmental epidemiology: cohort profile.
|title=Variability of Spleen and Mesenteric Lymph Node in Control Cynomolgus Monkeys ( Macaca fascicularis) from Nonclinical Safety Studies: A Retrospective Assessment.
|date=01.2017
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27884936
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30563426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241503
|full-text-url=https://sci-hub.do/10.1177/0192623318809073
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice.
|title=Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life.
|date=2015
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30523311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375790
}}
}}
==MTR==
* {{medline-title
* {{medline-title
|title=Genome-wide association studies of late-onset cardiovascular disease.
|title=Amide proton transfer-weighted magnetic resonance imaging of human brain aging at 3 Tesla.
|date=06.2015
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25870159
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32269932
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136735
}}
}}
==XRCC1==
* {{medline-title
* {{medline-title
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats].
|title=One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults.
|date=07.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208817
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180408.005
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.05.013
}}
}}
* {{medline-title
* {{medline-title
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.
|title=Test-retest reliability of myelin imaging in the human spinal cord: Measurement errors versus region- and aging-induced variations.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29293550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749716
}}
}}
==NES==
* {{medline-title
* {{medline-title
|title=X[[RCC1]] and XPD genetic polymorphisms and susceptibility to age-related cataract: a meta-analysis.
|title=Mini-review: Aging of the neuroendocrine system: Insights from nonhuman primate models.
|date=2015
|date=08.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873778
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31891735
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384174
|full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2019.109854
}}
}}
* {{medline-title
* {{medline-title
|title=Polymorphisms of DNA repair genes XPD (Lys751Gln) and [[XRCC1]] (Arg399Gln), and the risk of age-related cataract: a meta-analysis.
|title=Age Dependent Hypothalamic and Pituitary Responses to Novel Environment Stress or Lipopolysaccharide in Rats.
|date=07.2015
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25285569
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615881
|full-text-url=https://sci-hub.do/10.3109/02713683.2014.957325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868128
}}
}}
* {{medline-title
* {{medline-title
|title=Association between DNA repair genes (XPD and [[XRCC1]]) polymorphisms and susceptibility to age-related cataract ([[ARC]]): a meta-analysis.
|title=[Prediction of life expectancy for prostate cancer patients based on the kinetic theory of aging of living systems].
|date=08.2014
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24906341
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849878
|full-text-url=https://sci-hub.do/10.1007/s00417-014-2679-2
 
}}
}}
==ACAD10==
==NFE2L2==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=The double-edged sword of [[MTOR]] in autophagy deficiency induced-liver injury and tumorigenesis.
|date=12.2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31216956
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693464
}}
}}
* {{medline-title
* {{medline-title
|title=Metformin: a metabolic modulator.
|title=The Association of a Single-Nucleotide Polymorphism in the Nuclear Factor (Erythroid-Derived 2)-Like 2 Gene With Adverse Drug Reactions, Multimorbidity, and Frailty in Older People.
|date=07.02.2017
|date=22.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28122334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102514
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354711
|full-text-url=https://sci-hub.do/10.1093/gerona/glz131
}}
}}
* {{medline-title
* {{medline-title
|title=An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer.
|title=Immunohistochemical localization of Nrf2 in the human cochlea.
|date=15.12.2016
|date=01.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27984722
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29981724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231984
}}
}}
==NOS1==
* {{medline-title
* {{medline-title
|title=Metformin: Restraining Nucleocytoplasmic Shuttling to Fight Cancer and Aging.
|title=Prepubertal overexposure to manganese induce precocious puberty through GABA  receptor/nitric oxide pathway in immature female rats.
|date=15.12.2016
|date=30.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27984715
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31711775
|full-text-url=https://sci-hub.do/10.1016/j.cell.2016.11.058
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2019.109898
}}
}}
==ACAT1==
* {{medline-title
* {{medline-title
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity.
|date=06.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3
}}
}}
* {{medline-title
* {{medline-title
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
|title=[[NOS3]] Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels.
|date=15.12.2017
|date=11.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041791
}}
}}
==NOS3==
* {{medline-title
* {{medline-title
|title=Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men.
|title=Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation.
|date=07.2017
|date=22.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32455928
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.03.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290800
}}
}}
* {{medline-title
* {{medline-title
|title=Prenatal betaine exposure alleviates corticosterone-induced inhibition of [[CYP27A1]] expression in the liver of juvenile chickens associated with its promoter DNA methylation.
|title=Hypertension and longevity: role of genetic polymorphisms in renin-angiotensin-aldosterone system and endothelial nitric oxide synthase.
|date=15.05.2017
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039067
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30460536
|full-text-url=https://sci-hub.do/10.1016/j.ygcen.2016.12.014
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3470-1
}}
}}
==ACLY==
* {{medline-title
* {{medline-title
|title=In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase.
|title=[[NOS3]] Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels.
|date=10.2020
|date=11.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32666259
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527365
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041791
}}
}}
==NRF1==
* {{medline-title
* {{medline-title
|title=Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes.
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|date=04.2019
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677513
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2019.01.005
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
}}
}}
* {{medline-title
* {{medline-title
|title=Spermidine reduces cancer-related mortality in humans.
|title=Photobiomodulation and Coenzyme Q  Treatments Attenuate Cognitive Impairment Associated With Model of Transient Global Brain Ischemia in Artificially Aged Mice.
|date=02.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30354939
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983970
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333461
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434313
}}
}}
* {{medline-title
* {{medline-title
|title=ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway.
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
|date=01.2015
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25367309
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168
|full-text-url=https://sci-hub.do/10.1111/febs.13139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498
}}
}}
==ACOX1==
==OGT==


* {{medline-title
* {{medline-title
|title=Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes.
|title=ELT-2 promotes O-GlcNAc transferase [[OGT]]-1 expression to modulate Caenorhabditis elegans lifespan.
|date=04.2019
|date=06.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677513
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32628333
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2019.01.005
|full-text-url=https://sci-hub.do/10.1002/jcb.29817
}}
}}
* {{medline-title
* {{medline-title
|title=Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging.
|title=Neuronal O-GlcNAcylation Improves Cognitive Function in the Aged Mouse Brain.
|date=2018
|date=21.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765501
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31588002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199460
}}
}}
* {{medline-title
* {{medline-title
|title=Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging.
|title=Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor [[JUN]].
|date=11.07.2017
|date=31.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28545035
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30012597
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077742
}}
}}
* {{medline-title
==OXTR==
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
==ADAM17==


* {{medline-title
* {{medline-title
|title=ACE2/[[ADAM17]]/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19.
|title=Association of oxytocin levels and oxytocin receptor gene polymorphism (rs2254298) with cardiovascular risk factors in Brazilian elderly from Primary Health Care.
|date=2020
|date=09-10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31326852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575774
|full-text-url=https://sci-hub.do/10.1016/j.archger.2019.103903
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Impact of housing conditions on social behavior, neuroimmune markers, and oxytocin receptor expression in aged male and female Fischer 344 rats.
|date=25.07.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31100373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559851
}}
}}
* {{medline-title
* {{medline-title
|title=Role of Adipose Tissue Endothelial [[ADAM17]] in Age-Related Coronary Microvascular Dysfunction.
|title=Associations between oxytocin receptor gene ([[OXTR]]) methylation, plasma oxytocin, and attachment across adulthood.
|date=06.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29410310
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072619
}}
}}
* {{medline-title
==PFAS==
|title=Selective Inhibition of [[ADAM17]] Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28297575
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442763
}}
==ADAMTS9==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Associations between serum concentrations of perfluoroalkyl substances and DNA methylation in women exposed through drinking water: A pilot study in Ronneby, Sweden.
|date=02.2018
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33007577
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://sci-hub.do/10.1016/j.envint.2020.106148
}}
}}
* {{medline-title
* {{medline-title
|title=The [[ADAMTS9]] gene is associated with cognitive aging in the elderly in a Taiwanese population.
|title=Perfluorinated alkyl substances impede growth, reproduction, lipid metabolism and lifespan in Daphnia magna.
|date=2017
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28225792
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32521362
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321460
|full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2020.139682
}}
}}
* {{medline-title
* {{medline-title
|title=Adaptive sequence convergence of the tumor suppressor [[ADAMTS9]] between small-bodied mammals displaying exceptional longevity.
|title=The effect of weathering on per- and polyfluoroalkyl substances ([[PFAS]]s) from durable water repellent (DWR) clothing.
|date=26.02.2017
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28244876
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32062207
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361682
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2020.126100
}}
* {{medline-title
|title=Loss of C. elegans GON-1, an [[ADAMTS9]] Homolog, Decreases Secretion Resulting in Altered Lifespan and Dauer Formation.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26218657
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517882
}}
}}
==AFP==
==PI3==


* {{medline-title
* {{medline-title
|title=Effect of Alpha-Fetoprotein on Lifespan of Old Mice.
|title=Pulmonary Diseases and Ageing.
|date=12.2016
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28259124
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888649
|full-text-url=https://sci-hub.do/10.1134/S0006297916120087
|full-text-url=https://sci-hub.do/10.1007/978-981-13-3681-2_3
}}
}}
* {{medline-title
* {{medline-title
|title=Correlation between vitamin D levels and apoptosis in geriatric patients infected with hepatitis C virus genotype 4.
|title=CD57 identifies T cells with functional senescence before terminal differentiation and relative telomere shortening in patients with activated [[PI3]] kinase delta syndrome.
|date=2016
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27217734
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29790605
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862759
|full-text-url=https://sci-hub.do/10.1111/imcb.12169
}}
}}
* {{medline-title
* {{medline-title
|title=A new paradigm about HERV-K102 particle production and blocked release to explain cortisol mediated immunosenescence and age-associated risk of chronic disease.
|title=Maternal diabetes up-regulates NOX2 and enhances myocardial ischaemia/reperfusion injury in adult offspring.
|date=12.2015
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26760982
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377505
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867143
}}
}}
* {{medline-title
==PLAU==
|title=Are Performance Measures Necessary to Predict Loss of Independence in Elderly People?
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26273019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715230
}}
==AMPH==


* {{medline-title
* {{medline-title
|title=Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=01.09.2018
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29792867
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026035
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
* {{medline-title
* {{medline-title
|title=The effects of amphetamine exposure on juvenile rats on the neuronal morphology of the limbic system at prepubertal, pubertal and postpubertal ages.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=11.2016
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27208629
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2016.05.004
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
* {{medline-title
* {{medline-title
|title=Amphetamine modulates brain signal variability and working memory in younger and older adults.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=16.06.2015
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26034283
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
* {{medline-title
==PNP==
|title=Adolescent exposure to cocaine, amphetamine, and methylphenidate cross-sensitizes adults to methamphetamine with drug- and sex-specific effects.
|date=15.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25496784
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2014.12.002
}}
==BMF==


* {{medline-title
* {{medline-title
|title=lncRNA-ES3/miR-34c-5p/[[BMF]] axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs.
|title=Temporal Discrimination Thresholds and Proprioceptive Performance: Impact of Age and Nerve Conduction.
|date=17.01.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31803012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366973
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877661
}}
}}
* {{medline-title
* {{medline-title
|title=Aging, hematopoiesis, and the myelodysplastic syndromes.
|title=Polyneuropathy in Severely Obese Women Without Diabetes: Prevalence and Associated Factors.
|date=08.12.2017
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29222239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30536202
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142578
|full-text-url=https://sci-hub.do/10.1007/s11695-018-03627-0
}}
}}
* {{medline-title
* {{medline-title
|title=Bone marrow fat unsaturation in young adults is not affected by present or childhood obesity, but increases with age: A pilot study.
|title=Electrophysiological evidence for preserved primacy of lexical prediction in aging.
|date=11.2015
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26388537
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29852201
|full-text-url=https://sci-hub.do/10.1016/j.metabol.2015.08.014
|full-text-url=https://sci-hub.do/10.1016/j.neuropsychologia.2018.05.023
}}
}}
* {{medline-title
==POR==
|title=Loss of the proapoptotic BH3-only protein BCL-2 modifying factor prolongs the fertile life span in female mice.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24571986
|full-text-url=https://sci-hub.do/10.1095/biolreprod.113.116947
}}
==BPI==


* {{medline-title
* {{medline-title
|title=High TARC plasma levels confer protection to long living individuals by inducing M2 profile.
|title=The Ventricular System Enlarges Abnormally in the Seventies, Earlier in Men, and First in the Frontal Horn: A Study Based on More Than 3,000 Scans.
|date=01.2021
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002742
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31749695
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155305
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848156
}}
}}
* {{medline-title
* {{medline-title
|title=Circulating [[BPI]]FB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals.
|title=Clinical findings associated with development of postoperative reflux and short-term survival after small intestinal surgery in geriatric and mature nongeriatric horses.
|date=2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32547549
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272600
|full-text-url=https://sci-hub.do/10.1111/vsu.13217
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of postural deformities on back function and pain in patients with Parkinson's disease.
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia.
|date=2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31177242
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906
|full-text-url=https://sci-hub.do/10.3233/NRE-182637
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442
}}
}}
* {{medline-title
==PRDX1==
|title=The expression of the [[BPI]]FB4 and [[CXCR4]] associates with sustained health in long-living individuals from Cilento-Italy.
|date=22.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361669
}}
==CARF==


* {{medline-title
* {{medline-title
|title=Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
|title=Active vitamin D supplementation alleviates initiation and progression of nonalcoholic fatty liver disease by repressing the p53 pathway.
|date=22.05.2020
|date=15.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31112603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31756344
|full-text-url=https://sci-hub.do/10.1093/gerona/glz077
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.117086
}}
}}
* {{medline-title
* {{medline-title
|title=[[CARF]] is a multi-module regulator of cell proliferation and a molecular bridge between cellular senescence and carcinogenesis.
|title=[[PRDX1]] and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase.
|date=09.2017
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28754531
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29773556
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.07.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004070
}}
}}
* {{medline-title
* {{medline-title
|title=Collaborator of ARF ([[CARF]]) regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signaling.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=27.06.2014
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24825908
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140265
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==PRDX3==
* {{medline-title
* {{medline-title
|title=Molecular characterization of collaborator of ARF ([[CARF]]) as a DNA damage response and cell cycle checkpoint regulatory protein.
|title=Proteomic analyses reveal that ginsenoside Rg3([i]S[/i]) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin.
|date=01.04.2014
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24485912
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32148389
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2014.01.022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033328
}}
}}
==CASP3==
* {{medline-title
* {{medline-title
|title=Does cartilage ERα overexpression correlate with osteoarthritic chondrosenescence? Indications from [i]Labisia pumila[/i] OA mitigation.
|title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training.
|date=09.2019
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31502578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging.
|title=The impact of preserved Klotho gene expression on antioxidative stress activity in healthy kidney.
|date=28.12.2016
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29693450
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198498
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00486.2017
}}
}}
==PVR==
* {{medline-title
* {{medline-title
|title=Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium.
|title=Age estimation based on the volume change in the maxillary premolar crown using micro CT.
|date=27.11.2015
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26468292
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30597413
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661415
|full-text-url=https://sci-hub.do/10.1016/j.legalmed.2018.12.001
}}
}}
* {{medline-title
* {{medline-title
|title=A genome-wide scan reveals important roles of DNA methylation in human longevity by regulating age-related disease genes.
|title=Effect of age on the presence of comet tails at high altitude.
|date=2015
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25793257
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30056244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368809
|full-text-url=https://sci-hub.do/10.1016/j.resp.2018.07.010
}}
}}
==CCL19==
* {{medline-title
* {{medline-title
|title=Age-Related Gliosis Promotes Central Nervous System Lymphoma through [[CCL19]]-Mediated Tumor Cell Retention.
|title=Natural history of post-void residual urine volume over 5 years in community-dwelling older men: The Concord Health and Ageing in Men Project.
|date=16.09.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31526758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28940729
|full-text-url=https://sci-hub.do/10.1016/j.ccell.2019.08.001
|full-text-url=https://sci-hub.do/10.1002/nau.23415
}}
}}
==RHEB==
* {{medline-title
* {{medline-title
|title=Tumor-host signaling interaction reveals a systemic, age-dependent splenic immune influence on tumor development.
|title=The Rheb-TORC1 signaling axis functions as a developmental checkpoint.
|date=03.11.2015
|date=02.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26497558
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063671
}}
}}
* {{medline-title
* {{medline-title
|title=Differential Gene Expression Profiles Reflecting Macrophage Polarization in Aging and Periodontitis Gingival Tissues.
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|date=2015
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26397131
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
}}
}}
* {{medline-title
* {{medline-title
|title=CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs.
|title=CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in [i]C. elegans[/i].
|date=01.07.2015
|date=09.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26034175
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29515755
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475418
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839386
}}
}}
==CCL21==
==RHO==


* {{medline-title
* {{medline-title
|title=[[CCL21]]/[[CCR7]] axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
|title=Conditional reprogramming: next generation cell culture.
|date=26.03.2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30914733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32963937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435673
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488362
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|title=SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells.
|date=01.2018
|date=18.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32246845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232010
}}
}}
* {{medline-title
* {{medline-title
|title=Artery Tertiary Lymphoid Organs: Powerhouses of Atherosclerosis Immunity.
|title=Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging.
|date=2016
|date=28.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27777573
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30274229
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056324
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210377
}}
}}
* {{medline-title
==ROCK1==
|title=CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs.
|date=01.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26034175
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475418
}}
==CCL3==


* {{medline-title
* {{medline-title
|title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau.
|title=Disruption of both [[ROCK1]] and [[ROCK2]] genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging.
|date=03.09.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082275
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30848941
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529334
}}
}}
* {{medline-title
* {{medline-title
|title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles.
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|date=05.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|full-text-url=https://sci-hub.do/10.1620/tjem.245.29
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor.
|title=Vascular Smooth Muscle Contractile Function Declines With Age in Skeletal Muscle Feed Arteries.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30108507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079263
}}
* {{medline-title
|title=Changes in the expression of the Toll-like receptor system in the aging rat kidneys.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014502
}}
}}
==CCN1==
==RUNX2==


* {{medline-title
* {{medline-title
|title=Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis.
|title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity.
|date=09.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32651107
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681
|full-text-url=https://sci-hub.do/10.1016/j.rbmo.2020.04.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of cellular communication network factor 1 ([[CCN1]])-driven senescence slows down cartilage inflammaging and osteoarthritis.
|title=Chondrocyte-Specific [[RUNX2]] Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice.
|date=10.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32622876
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189030
|full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047611
}}
}}
* {{medline-title
* {{medline-title
|title=The senescence-associated matricellular protein [[CCN1]] in plasma of human subjects with idiopathic pulmonary fibrosis.
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|date=01.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023981
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
}}
}}
* {{medline-title
==S100A8==
|title=[[CCN1]] (CYR61) and [[CCN3]] (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties.
|date=03.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26744771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853050
}}
==CD22==


* {{medline-title
* {{medline-title
|title=[[CD22]] blockade restores homeostatic microglial phagocytosis in ageing brains.
|title=[[S100A8]], which increases with age, induces cellular senescence-like changes in bovine oviduct epithelial cells.
|date=04.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237976
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6574119
|full-text-url=https://sci-hub.do/10.1111/aji.13163
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves.
|title=Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model.
|date=03.2018
|date=06.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991479
|full-text-url=https://sci-hub.do/10.24425/119039
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078409
}}
}}
* {{medline-title
* {{medline-title
|title=Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice.
|title=Lung cellular senescence is independent of aging in a mouse model of COPD/emphysema.
|date=01.07.2015
|date=13.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25987743
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29899396
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1403139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998122
}}
}}
* {{medline-title
==SCT==
|title=Double negative (CD19 IgG IgD-[[CD27]]-) B lymphocytes: a new insight from telomerase in healthy elderly, in centenarian offspring and in Alzheimer's disease patients.
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951896
|full-text-url=https://sci-hub.do/10.1016/j.imlet.2014.06.003
}}
==CES1==


* {{medline-title
* {{medline-title
|title=[Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog].
|title=Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults.
|date=2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31061351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528961
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00228
|full-text-url=https://sci-hub.do/10.1519/JSC.0000000000002536
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Dependent Absolute Abundance of Hepatic Carboxylesterases ([[CES1]] and [[CES2]]) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants.
|title=High-intensity interval training improves acute plasma volume responses to exercise that is age dependent.
|date=02.2017
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27895113
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29464883
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820462
}}
}}
* {{medline-title
* {{medline-title
|title=Identifying clinically relevant sources of variability: The clopidogrel challenge.
|title=Communication technology adoption among older adult veterans: the interplay of social and cognitive factors.
|date=02.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27557470
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29019416
|full-text-url=https://sci-hub.do/10.1002/cpt.459
|full-text-url=https://sci-hub.do/10.1080/13607863.2017.1381946
}}
}}
* {{medline-title
==SDC1==
|title=Age-Dependent Human Hepatic Carboxylesterase 1 ([[CES1]]) and Carboxylesterase 2 ([[CES2]]) Postnatal Ontogeny.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26825642
|full-text-url=https://sci-hub.do/10.1124/dmd.115.068957
}}
==CLN3==


* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Olmesartan alleviates bleomycin-mediated vascular smooth muscle cell senescence via the miR-665/[[SDC1]] axis.
|date=09.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33042414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540088
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent alterations in neuronal activity in the hippocampus and visual cortex in a mouse model of Juvenile Neuronal Ceroid Lipofuscinosis ([[CLN3]]).
|title=Sulfated syndecan 1 is critical to preventing cellular senescence by modulating fibroblast growth factor receptor endocytosis.
|date=04.2017
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28042098
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32530114
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2016.12.022
|full-text-url=https://sci-hub.do/10.1096/fj.201902714R
}}
}}
* {{medline-title
* {{medline-title
|title=Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease).
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|date=15.12.2015
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26450516
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654058
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
}}
}}
* {{medline-title
==SERPINE1==
|title=Finding the most appropriate mouse model of juvenile [[CLN3]] (Batten) disease for therapeutic studies: the importance of genetic background and gender.
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26035843
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381334
}}
==CPE==


* {{medline-title
* {{medline-title
|title=Cross-Sectional and Cumulative Longitudinal Central Nervous System Penetration Effectiveness Scores Are Not Associated With Neurocognitive Impairment in a Well Treated Aging Human Immunodeficiency Virus-Positive Population in Switzerland.
|title=Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes.
|date=07.2019
|date=15.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612860
|full-text-url=https://sci-hub.do/10.1016/j.placenta.2019.12.012
}}
}}
* {{medline-title
* {{medline-title
|title=COCOA (Theobroma cacao) Polyphenol-Rich Extract Increases the Chronological Lifespan of Saccharomyces cerevisiae.
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|date=2016
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29240368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
}}
}}
* {{medline-title
* {{medline-title
|title=The choroid plexus-cerebrospinal fluid interface in Alzheimer's disease: more than just a barrier.
|title=A null mutation in [i][[SERPINE1]][/i] protects against biological aging in humans.
|date=04.2016
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27212900
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29152572
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870896
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687852
}}
}}
* {{medline-title
==SHH==
|title=Characterization of Clostridium perfringens in the feces of adult horses and foals with acute enterocolitis.
|date=01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24396174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878003
}}
==CRY1==


* {{medline-title
* {{medline-title
|title=Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-[[CRY1]] Transgenic Mice.
|title=Recent advances in [[SHH]] medulloblastoma progression: tumor suppressor mechanisms and the tumor microenvironment.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31179341
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31700613
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820827
}}
}}
* {{medline-title
* {{medline-title
|title=Investigating circadian clock gene expression in human tendon biopsies from acute exercise and immobilization studies.
|title=An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through [[SERPINB2]].
|date=06.2019
|date=03.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080015
|full-text-url=https://sci-hub.do/10.1007/s00421-019-04129-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612665
}}
}}
* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|date=21.11.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
}}
* {{medline-title
|title=Circadian Clock Control by Polyamine Levels through a Mechanism that Declines with Age.
|date=03.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26456331
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2015.09.011
}}
}}
==CTCF==
==SIRT5==


* {{medline-title
* {{medline-title
|title=New targeted approaches for epigenetic age predictions.
|title=Lysine malonylation and propionylation are prevalent in human lens proteins.
|date=24.06.2020
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32580727
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957740
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty.
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|date=2018
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765957
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
}}
}}
* {{medline-title
* {{medline-title
|title=[[HMGB2]] Loss upon Senescence Entry Disrupts Genomic Organization and Induces [[CTCF]] Clustering across Cell Types.
|title=Expression of Sirtuins in the Retinal Neurons of Mice, Rats, and Humans.
|date=17.05.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706538
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29249955
|full-text-url=https://sci-hub.do/10.1016/j.molcel.2018.03.030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715387
}}
}}
* {{medline-title
==SLC6A4==
|title=Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25880792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623031
}}
==CXCR1==


* {{medline-title
* {{medline-title
|title=Harmful neutrophil subsets in patients with ischemic stroke: Association with disease severity.
|title=The Psilocybin-Telomere Hypothesis: An empirically falsifiable prediction concerning the beneficial neuropsychopharmacological effects of psilocybin on genetic aging.
|date=07.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31355307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634774
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624098
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2019.109406
}}
}}
* {{medline-title
* {{medline-title
|title=Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells.
|title=Epigenetics-by-sex interaction for somatization conferred by methylation at the promoter region of [[SLC6A4]] gene.
|date=15.06.2017
|date=08.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28418782
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30201454
|full-text-url=https://sci-hub.do/10.1089/scd.2016.0324
|full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2018.09.002
}}
* {{medline-title
|title=The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via [[CXCR1]]-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27769935
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2016.10.011
}}
}}
* {{medline-title
* {{medline-title
|title=Habitual physical activity is associated with the maintenance of neutrophil migratory dynamics in healthy older adults.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=08.2016
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26928196
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929133
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==CYP17A1==
==SNAI1==


* {{medline-title
* {{medline-title
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio).
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|date=03.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
}}
}}
* {{medline-title
* {{medline-title
|title=Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs.
|title=O-GlcNAcylation is required for mutant [[KRAS]]-induced lung tumorigenesis.
|date=01.03.2017
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28166986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130254
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2016.11.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205381
}}
}}
* {{medline-title
* {{medline-title
|title=[[CYP17A1]] Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study.
|title=Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16  inactivation.
|date=04.2016
|date=26.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26297028
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482580
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828408
}}
}}
* {{medline-title
==SNAP25==
|title=Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25275628
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183565
}}
==CYP3A5==


* {{medline-title
* {{medline-title
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia.
|title=The Biological Foundations of Sarcopenia: Established and Promising Markers.
|date=12.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31457015
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700259
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits.
|title=Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age.
|date=06.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396010
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29496544
|full-text-url=https://sci-hub.do/10.1016/j.ijheh.2017.03.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483375
}}
}}
* {{medline-title
* {{medline-title
|title=Donor [[CYP3A5]] genotype influences tacrolimus disposition on the first day after paediatric liver transplantation.
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells.
|date=06.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28044353
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327
}}
}}
* {{medline-title
==SOCS3==
|title=Relationship between mRNA expression levels of [[CYP3A4]], [[CYP3A5]] and SXR in peripheral mononuclear blood cells and aging in young kidney transplant recipients under tacrolimus treatment.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25916520
|full-text-url=https://sci-hub.do/10.2217/pgs.15.18
}}
==DICER1==


* {{medline-title
* {{medline-title
|title=[[DICER1]]: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging.
|title=Congenital Hypothyroidism is Associated With Impairment of the Leptin Signaling Pathway in the Hypothalamus in Male Wistar Animals in Adult Life.
|date=2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087677
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30943548
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066587
|full-text-url=https://sci-hub.do/10.1055/a-0876-6007
}}
}}
* {{medline-title
* {{medline-title
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability.
|title=Deletion of suppressor of cytokine signaling 3 ([[SOCS3]]) in muscle stem cells does not alter muscle regeneration in mice after injury.
|date=06.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30811469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392323
}}
}}
* {{medline-title
* {{medline-title
|title=Metformin-mediated increase in [[DICER1]] regulates microRNA expression and cellular senescence.
|title=Age-related remodeling of the JAK/STAT/SOCS signaling pathway and associated myocardial changes: From histological to molecular level.
|date=06.2016
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26990999
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854919
|full-text-url=https://sci-hub.do/10.1016/j.aanat.2017.07.003
}}
}}
* {{medline-title
==SPRY1==
|title=Radiographic screening of infants and young children with genetic predisposition for rare malignancies: DI[[CER1]] mutations and pleuropulmonary blastoma.
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25794098
|full-text-url=https://sci-hub.do/10.2214/AJR.14.12802
}}
==DYRK1A==


* {{medline-title
* {{medline-title
|title=Altered age-linked regulation of plasma [[DYRK1A]] in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load.
|title=Sprouty1 Prevents Cellular Senescence Maintaining Proliferation and Differentiation Capacity of Human Adipose Stem/Progenitor Cells.
|date=2020
|date=13.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32642550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32304210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331462
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662188
}}
}}
* {{medline-title
* {{medline-title
|title=Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes.
|title=Mechanism of [[SPRY1]] methylation regulating natural aging of skin epidermal cells.
|date=10.2017
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28647555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31483543
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2017.06.010
|full-text-url=https://sci-hub.do/10.1111/jocd.13126
}}
}}
* {{medline-title
* {{medline-title
|title=The protein kinase MBK-1 contributes to lifespan extension in [i]daf-2[/i] mutant and germline-deficient [i]Caenorhabditis elegans[/i].
|title=MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting [[SPRY1]] via the [[PTEN]]/PI3K/AKT signaling pathway.
|date=25.05.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28562327
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29316313
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489721
}}
}}
* {{medline-title
==SRC==
|title=Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26363314
|full-text-url=https://sci-hub.do/10.1016/j.pbb.2015.09.002
}}
==EBP==


* {{medline-title
* {{medline-title
|title=National dissemination of multiple evidence-based disease prevention programs: reach to vulnerable older adults.
|title=Metabolic characteristics of CD8  T cell subsets in young and aged individuals are not predictive of functionality.
|date=2014
|date=05.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25964901
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32504069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410420
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275080
}}
}}
* {{medline-title
* {{medline-title
|title=Roles for education in development and implementation of evidence-based practices for community programs for older adults.
|title=Overexpression of steroid receptor coactivators alleviates hyperglycemia-induced endothelial cell injury in rats through activating the PI3K/Akt pathway.
|date=2015
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25950811
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30089865
|full-text-url=https://sci-hub.do/10.1080/02701960.2015.1031895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786429
}}
}}
* {{medline-title
* {{medline-title
|title=Methods for streamlining intervention fidelity checklists: an example from the chronic disease self-management program.
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=2014
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25964941
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410323
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
}}
==SYK==
* {{medline-title
* {{medline-title
|title=Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome/IL-1β for steatohepatitis.
|title=miR-25-3p promotes endothelial cell angiogenesis in aging mice via TULA-2/[[SYK]]/VEGFR-2 downregulation.
|date=08.2015
|date=17.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25847140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33201836
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531067
|full-text-url=https://sci-hub.do/10.18632/aging.103834
}}
}}
==EFEMP1==
* {{medline-title
* {{medline-title
|title=A novel age-related venous amyloidosis derived from [[EGF]]-containing fibulin-like extracellular matrix protein 1.
|title=Identification of [[SYK]] inhibitor, R406 as a novel senolytic agent.
|date=04.2019
|date=07.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30565683
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32379705
|full-text-url=https://sci-hub.do/10.1002/path.5203
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244031
}}
}}
* {{medline-title
* {{medline-title
|title=Mutant Fibulin-3 Causes Proteoglycan Accumulation and Impaired Diffusion Across Bruch's Membrane.
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=01.06.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28622396
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477800
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
}}
==TET1==
* {{medline-title
* {{medline-title
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|date=05.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
}}
}}
* {{medline-title
* {{medline-title
|title=Role of Fibulin 3 in Aging-Related Joint Changes and Osteoarthritis Pathogenesis in Human and Mouse Knee Cartilage.
|title=Epigenetic Co-Deregulation of [[EZH2]]/[[TET1]] is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer.
|date=03.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27780308
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30809307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328782
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376470
}}
}}
==EPHA1==
* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=DNA Hydroxymethylation Levels Are Altered in Blood Cells From Down Syndrome Persons Enrolled in the MARK-AGE Project.
|date=16.08.2019
|date=09.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29069286
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946825
}}
}}
==TLR1==
* {{medline-title
* {{medline-title
|title=Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study.
|title=Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle.
|date=2017
|date=01.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28269768
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32969782
|full-text-url=https://sci-hub.do/10.3233/JAD-160774
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00615.2020
}}
}}
* {{medline-title
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|title=Association of TLR gene variants in a Czech Red Pied cattle population with reproductive traits.
|date=11.04.2017
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31901560
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2019.109997
}}
}}
* {{medline-title
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.
|date=04.2016
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149
}}
}}
==ESR2==
==TMEM106B==


* {{medline-title
* {{medline-title
|title=Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain.
|title=Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology.
|date=01.04.2018
|date=05.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28334178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32526197
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416464
}}
}}
* {{medline-title
* {{medline-title
|title=Age- and menopause-related differences in subcutaneous adipose tissue estrogen receptor mRNA expression.
|title=[[TMEM106B]], a risk factor for FTLD and aging, has an intrinsically disordered cytoplasmic domain.
|date=05.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28288896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30332472
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192649
}}
}}
* {{medline-title
* {{medline-title
|title=Differential roles of estrogen receptors, [[ESR1]] and [[ESR2]], in adult rat spermatogenesis.
|title=[[TMEM106B]] haplotypes have distinct gene expression patterns in aged brain.
|date=15.06.2016
|date=03.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27004961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29970152
|full-text-url=https://sci-hub.do/10.1016/j.mce.2016.03.024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029036
}}
}}
* {{medline-title
==TNC==
|title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460
}}
==FABP4==


* {{medline-title
* {{medline-title
|title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation.
|title=Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging.
|date=05.2018
|date=18.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33217999
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698786
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial [[APLNR]] regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.
|title=Tenascin-C expression controls the maturation of articular cartilage in mice.
|date=13.09.2017
|date=17.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32066496
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027060
}}
}}
* {{medline-title
* {{medline-title
|title=Determination of the Mechanisms that Cause Sarcopenia through cDNA Microarray.
|title=Effects of hydrothermal aging, thermal cycling, and water storage on the mechanical properties of a machinable resin-based composite containing nano-zirconia fillers.
|date=2017
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28555711
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31877525
|full-text-url=https://sci-hub.do/10.14283/jfa.2017.13
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2019.103522
}}
}}
* {{medline-title
==TRA==
|title=Bariatric surgery and diet-induced long-term caloric restriction protect subcutaneous adipose-derived stromal/progenitor cells and prolong their life span in formerly obese humans.
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24747059
|full-text-url=https://sci-hub.do/10.1016/j.exger.2014.03.030
}}
==FBL==


* {{medline-title
* {{medline-title
|title=APPLICATION OF A NOVEL QUANTITATIVE TRACTOGRAPHY-BASED ANALYSIS OF DIFFUSION TENSOR IMAGING TO EXAMINE FIBER BUNDLE LENGTH IN HUMAN CEREBRAL WHITE MATTER.
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|date=04.2016
|date=10.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27721932
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055128
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
}}
}}
* {{medline-title
* {{medline-title
|title=Cognitive reserve moderates the relationship between neuropsychological performance and white matter fiber bundle length in healthy older adults.
|title=Sex-specific regulation of aging in Caenorhabditis elegans.
|date=06.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26961092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29493066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083104
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946081
}}
}}
* {{medline-title
* {{medline-title
|title=Fiber bundle length and cognition: a length-based tractography MRI study.
|title=Age-Associated Decline in Thymic B Cell Expression of Aire and Aire-Dependent Self-Antigens.
|date=12.2015
|date=30.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25376332
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29386114
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813500
}}
}}
* {{medline-title
==TRAF3==
|title=White matter changes with age utilizing quantitative diffusion MRI.
|date=15.07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24928121
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117364
}}
==FKBP5==


* {{medline-title
* {{medline-title
|title=Epigenetic upregulation of [[FKBP5]] by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk.
|title=[[TRAF3]], a Target of MicroRNA-363-3p, Suppresses Senescence and Regulates the Balance Between Osteoblastic and Adipocytic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells.
|date=04.06.2019
|date=01.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113877
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32111144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561294
|full-text-url=https://sci-hub.do/10.1089/scd.2019.0276
}}
}}
* {{medline-title
* {{medline-title
|title=The common functional [[FKBP5]] variant rs1360780 is associated with altered cognitive function in aged individuals.
|title=TGFβ-induced degradation of [[TRAF3]] in mesenchymal progenitor cells causes age-related osteoporosis.
|date=21.10.2014
|date=26.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25331639
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31243287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595054
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated epigenetic upregulation of the [[FKBP5]] gene selectively impairs stress resiliency.
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes.
|date=2014
|date=12.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25191701
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941
}}
}}
==TRIM59==
* {{medline-title
* {{medline-title
|title=Role of [[FKBP5]] in emotion processing: results on amygdala activity, connectivity and volume.
|title=DNA methylation of the [[ELOVL2]], [[FHL2]], [[KLF14]], C1orf132/MIR29B2C, and [[TRIM59]] genes for age prediction from blood, saliva, and buccal swab samples.
|date=2015
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24756342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30300865
|full-text-url=https://sci-hub.do/10.1007/s00429-014-0729-5
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010
}}
}}
==GALT==
* {{medline-title
* {{medline-title
|title=Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life.
|title=Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing.
|date=03.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30523311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031222
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375790
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.07.007
}}
}}
* {{medline-title
* {{medline-title
|title=Dietary Animal Plasma Proteins Improve the Intestinal Immune Response in Senescent Mice.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=11.12.2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29232896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748796
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==TRPV1==
* {{medline-title
* {{medline-title
|title=Ageing combines [[CD4]] T cell lymphopenia in secondary lymphoid organs and T cell accumulation in gut associated lymphoid tissue.
|title=Reduced bladder responses to capsaicin and GSK-1016790A in retired-breeder female rats with diminished volume sensitivity.
|date=2014
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24829607
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019934
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020584
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00198.2018
}}
}}
* {{medline-title
* {{medline-title
|title=Influence of ageing on the gastrointestinal environment of the rat and its implications for drug delivery.
|title=Expression of CGRP neurotransmitter and vascular genesis marker mRNA is age-dependent in superior cervical ganglia of senescence-accelerated prone mice.
|date=01.10.2014
|date=18.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24834990
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154859
|full-text-url=https://sci-hub.do/10.1016/j.ejps.2014.05.004
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2017.11.034
}}
}}
==GCLM==
* {{medline-title
* {{medline-title
|title=Silencing Bach1 alters aging-related changes in the expression of Nrf2-regulated genes in primary human bronchial epithelial cells.
|title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases.
|date=15.09.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31422075
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699
|full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108074
|full-text-url=https://sci-hub.do/10.1111/nmo.13185
}}
}}
==TSC1==
* {{medline-title
* {{medline-title
|title=Ontogeny and aging of Nrf2 pathway genes in livers of rats.
|title=mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism.
|date=15.06.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29689272
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30924297
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2018.04.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516169
}}
}}
* {{medline-title
* {{medline-title
|title=Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates.
|title=[[FTO]] is involved in Alzheimer's disease by targeting [[TSC1]]-mTOR-Tau signaling.
|date=04.2018
|date=25.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501742
|full-text-url=https://sci-hub.do/10.1111/nyas.13556
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.02.201
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-related decline in the induction of Nrf2-regulated antioxidant genes in human bronchial epithelial cells.
|title=Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner.
|date=04.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28863281
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29023667
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576992
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716871
}}
}}
==GIT2==
==VDAC1==


* {{medline-title
* {{medline-title
|title=Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic [[GIT2]] in aging trajectories.
|title=Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and [[VDAC1]] predicts mammalian longevity.
|date=12.2019
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31574270
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32353747
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111150
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191849
}}
}}
* {{medline-title
* {{medline-title
|title=[[GIT2]]-A keystone in ageing and age-related disease.
|title=Changes in the expression of oxidative phosphorylation complexes in the aging intestinal mucosa.
|date=05.2018
|date=01.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32173460
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110924
}}
}}
* {{medline-title
* {{medline-title
|title=Genomic deletion of [[GIT2]] induces a premature age-related thymic dysfunction and systemic immune system disruption.
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|date=04.03.2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28260693
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391227
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
}}
}}
* {{medline-title
==VHL==
|title=[[GIT2]] Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26834700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716144
}}
==GLS==


* {{medline-title
* {{medline-title
|title=Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography.
|title=Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a [[VHL]]-1-independent transcriptional response.
|date=15.07.2018
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29784576
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399915
|full-text-url=https://sci-hub.do/10.1016/j.amjcard.2018.03.355
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00194-0
}}
}}
* {{medline-title
* {{medline-title
|title=Future Perspectives for Management of Stage A Heart Failure.
|title=The Energy Maintenance Theory of Aging: Maintaining Energy Metabolism to Allow Longevity.
|date=01.07.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731506
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29901833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055033
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314662
}}
}}
* {{medline-title
* {{medline-title
|title=Reference Ranges of Left Ventricular Strain Measures by Two-Dimensional Speckle-Tracking Echocardiography in Children: A Systematic Review and Meta-Analysis.
|title=Shorter telomere length increases age-related tumor risks in von Hippel-Lindau disease patients.
|date=03.2016
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26747685
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28776935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603836
}}
}}
* {{medline-title
==VIM==
|title=Cardiorespiratory fitness modifies the relationship between myocardial function and cerebral blood flow in older adults.
|date=01.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26032886
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029275
}}
==GRK2==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 2 modifies the ability of Caenorhabditis elegans to survive oxidative stress.
|title=Establishment and characterization of a fibroblast cell line from postmortem skin of an adult Chinese muntjac (Muntiacus reevesi).
|date=16.10.2020
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33064264
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31898011
|full-text-url=https://sci-hub.do/10.1007/s12192-020-01168-z
|full-text-url=https://sci-hub.do/10.1007/s11626-019-00422-8
}}
}}
* {{medline-title
* {{medline-title
|title=G protein coupled receptor kinases modulate Caenorhabditis elegans reactions to heat stresses.
|title=The effect of test modality on dynamic exercise biomarkers in children, adolescents, and young adults.
|date=01.10.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768194
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31353834
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.07.121
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796805
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging.
|title=Centenarians Overexpress Pluripotency-Related Genes.
|date=01.05.2020
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32216616
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346533
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
}}
}}
* {{medline-title
==VWF==
|title=Senescent Cells Differentially Translate Senescence-Related mRNAs Via Ribosome Heterogeneity.
|date=18.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30285098
|full-text-url=https://sci-hub.do/10.1093/gerona/gly228
}}
==GSTT1==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Von Willebrand disease in the elderly: clinical perspectives.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30214173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124462
}}
}}
* {{medline-title
* {{medline-title
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
|title=Comorbidities associated with higher von Willebrand factor ([[VWF]]) levels may explain the age-related increase of [[VWF]] in von Willebrand disease.
|date=2016
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29767844
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032952
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of [[APOE]] rs429358, rs7412 and [[GSTM1]]/[[GSTT1]] Polymorphism on Plasma and Erythrocyte Antioxidant Parameters and Cognition in Old Chinese Adults.
|title=The Association of Aging With Von Willebrand Factor Levels and Bleeding Risk in Type 1 Von Willebrand Disease.
|date=24.09.2015
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26404360
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28874064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632411
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714664
}}
}}
* {{medline-title
==WNT1==
|title=[Frequency of gene polymorphic variants (phase II) of biotransformation of [[GSTT1]] and [[GSTM1]] xenobiotics among long-livers (Precarpathian region)].
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640692
 
}}
==HAL==


* {{medline-title
* {{medline-title
|title=Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population.
|title=Plasma proteomic profile of age, health span, and all-cause mortality in older adults.
|date=06-09.2018
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31066639
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33089916
|full-text-url=https://sci-hub.do/10.1080/15360288.2018.1513434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681045
}}
}}
* {{medline-title
* {{medline-title
|title=Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats.
|title=Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.
|date=06.2019
|date=07.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31049689
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30686765
|full-text-url=https://sci-hub.do/10.1007/s00540-019-02646-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408230
}}
}}
* {{medline-title
* {{medline-title
|title=Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice.
|title=Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.
|date=08.2017
|date=07.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28421257
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30404864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538925
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aau7137
}}
}}
* {{medline-title
==WNT3A==
|title=Differential effects of intermittent versus continuous haloperidol treatment throughout adolescence on haloperidol sensitization and social behavior in adulthood.
|date=03.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24942467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134967
}}
==HCN2==


* {{medline-title
* {{medline-title
|title=Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes.
|title=Chronic WNT/β-catenin signaling induces cellular senescence in lung epithelial cells.
|date=11.11.2015
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109549
|full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000455
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2020.109588
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated expression of HCN channel isoforms in rat sinoatrial node.
|title=[[WNT3A]] accelerates delayed alveolar bone repair in ovariectomized mice.
|date=02.2016
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341471
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31338519
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935443
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007703
}}
}}
* {{medline-title
* {{medline-title
|title=Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation.
|title=WNT-activated bone grafts repair osteonecrotic lesions in aged animals.
|date=09.2015
|date=27.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005035
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29079746
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526032
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660190
}}
* {{medline-title
|title=Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse.
|date=27.02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352274
}}
}}
==HIRA==
==XIAP==


* {{medline-title
* {{medline-title
|title=Pak2 kinase promotes cellular senescence and organismal aging.
|title=Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and [[XIAP]].
|date=02.07.2019
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31209047
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613284
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.05.017
}}
}}
* {{medline-title
* {{medline-title
|title=ChIP-Sequencing to Map the Epigenome of Senescent Cells Using Benzonase Endonuclease.
|title=Modulated electro-hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro.
|date=2016
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27423868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31183995
|full-text-url=https://sci-hub.do/10.1016/bs.mie.2016.01.021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675742
}}
}}
* {{medline-title
* {{medline-title
|title=O-linked N-acetylglucosamine transferase ([[OGT]]) interacts with the histone chaperone [[HIRA]] complex and regulates nucleosome assembly and cellular senescence.
|title=Protective effect of xanthohumol against age-related brain damage.
|date=07.06.2016
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27217568
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988580
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011
}}
}}
* {{medline-title
==XPA==
|title=[[HIRA]] orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.
|date=15.12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25512559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265675
}}
==HMGA2==


* {{medline-title
* {{medline-title
|title=4D Genome Rewiring during Oncogene-Induced and Replicative Senescence.
|title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.
|date=07.05.2020
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32220303
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141
}}
}}
* {{medline-title
* {{medline-title
|title=The protective effects of [[HMGA2]] in the senescence process of bone marrow-derived mesenchymal stromal cells.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=04.2020
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32068957
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://sci-hub.do/10.1002/term.3023
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
* {{medline-title
* {{medline-title
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
|title=Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans.
|date=05.11.2018
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28934497
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766164
}}
* {{medline-title
|title=Molecular differences between stromal cell populations from deciduous and permanent human teeth.
|date=18.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25927523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417277
}}
==HMGCR==
 
* {{medline-title
|title=Cholesterol Homeostasis: An In Silico Investigation into How Aging Disrupts Its Key Hepatic Regulatory Mechanisms.
|date=30.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33007859
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7599957
}}
* {{medline-title
|title=Artesunate inhibits the mevalonate pathway and promotes glioma cell senescence.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31746143
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933330
}}
* {{medline-title
|title=Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30609251
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413652
}}
* {{medline-title
|title=The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
|date=15.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125687
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.08.003
}}
==HSPA8==
 
* {{medline-title
|title=Influence of Normal Aging on Brain Autophagy: A Complex Scenario.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30914945
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421305
}}
* {{medline-title
|title=Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone [[HSPA8]] and the ubiquitin ligase UBE2D.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30368041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202877
}}
* {{medline-title
|title=Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29867441
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952035
}}
* {{medline-title
|title=Age-Related Decrease in Heat Shock 70-kDa Protein 8 in Cerebrospinal Fluid Is Associated with Increased Oxidative Stress.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27507943
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960228
}}
==ID1==
 
* {{medline-title
|title=Commentary on Some Recent Theses Relevant to Combating Aging: April 2019.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30957657
|full-text-url=https://sci-hub.do/10.1089/rej.2019.2201
}}
* {{medline-title
|title=ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
|date=12.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847931
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603998
}}
* {{medline-title
|title=Expansion of adipose tissue-derived stromal cells at "physiologic" hypoxia attenuates replicative senescence.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28589682
|full-text-url=https://sci-hub.do/10.1002/cbf.3267
}}
* {{medline-title
|title=Endoglin overexpression mediates gastric cancer peritoneal dissemination by inducing mesothelial cell senescence.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27067789
|full-text-url=https://sci-hub.do/10.1016/j.humpath.2015.12.023
}}
==IFNG==
 
* {{medline-title
|title=Glutathione Peroxidase 3 Delivered by hiPSC-[[MSC]]s Ameliorated Hepatic IR Injury via Inhibition of Hepatic Senescence.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29290803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743470
}}
* {{medline-title
|title=Impact of aging on host immune response and survival in melanoma: an analysis of 3 patient cohorts.
|date=19.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27760559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070187
}}
* {{medline-title
|title=Age-related profiling of DNA methylation in CD8  T cells reveals changes in immune response and transcriptional regulator genes.
|date=19.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26286994
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541364
}}
* {{medline-title
|title=Lifespan of mice and primates correlates with immunoproteasome expression.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25866968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463211
}}
==IGFBP2==
 
* {{medline-title
|title=Intracellular Insulin-like growth factor binding protein 2 ([[IGFBP2]]) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21.
|date=17.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32302288
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202509
}}
* {{medline-title
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
}}
* {{medline-title
|title=IGFBP-2 and aging: a 20-year longitudinal study on IGFBP-2, IGF-I, BMI, insulin sensitivity and mortality in an aging population.
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30475224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445262
}}
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
==IGFBP5==
 
* {{medline-title
|title=Intracellular Heat Shock Protein 70 Deficiency in Pulmonary Fibrosis.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30543447
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543745
}}
* {{medline-title
|title=Blunted satellite cell response is associated with dysregulated IGF-1 expression after exercise with age.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30062517
|full-text-url=https://sci-hub.do/10.1007/s00421-018-3954-4
}}
* {{medline-title
|title=Material-induced Senescence (MIS): Fluidity Induces Senescent Type Cell Death of Lung Cancer Cells via Insulin-Like Growth Factor Binding Protein 5.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29187894
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706090
}}
* {{medline-title
|title=Transcriptomic profiling suggests a role for [[IGFBP5]] in premature senescence of endothelial cells after chronic low dose rate irradiation.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24646080
|full-text-url=https://sci-hub.do/10.3109/09553002.2014.905724
}}
==IGFBP7==
 
* {{medline-title
|title=Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31904196
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031646
}}
* {{medline-title
|title=Unique sex- and age-dependent effects in protective pathways in acute kidney injury.
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28679590
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625098
}}
* {{medline-title
|title=A-to-I RNA editing of the [[IGFBP7]] transcript increases during aging in porcine brain tissues.
|date=21.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27687550
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.09.125
}}
* {{medline-title
|title=Emerging role of insulin-like growth factor-binding protein 7 in hepatocellular carcinoma.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27508172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918263
}}
==INSL3==
 
* {{medline-title
|title=Effect of Thyroxine Replacement on Leydig Cell and Sertoli Cell Function in Men with Hypothyroidism.
|date=05-06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33083267
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539029
}}
* {{medline-title
|title=Age related and seasonal changes of plasma concentrations of insulin-like peptide 3 and testosterone from birth to early-puberty in Thoroughbred male horses.
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31029851
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2019.04.014
}}
* {{medline-title
|title=Plasma insulin-like peptide 3 concentrations are acutely regulated by luteinizing hormone in pubertal Japanese Black beef bulls.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26318230
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2015.07.039
}}
* {{medline-title
|title=[[INSL3]] stimulates spermatogonial differentiation in testis of adult zebrafish (Danio rerio).
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26077926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735252
}}
==IPP==
 
* {{medline-title
|title=Toxic effect of the novel chiral insecticide [[IPP]] and its biodegradation intermediate in nematode Caenorhabditis elegans.
|date=30.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30153642
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.08.059
}}
* {{medline-title
|title=The inositol pyrophosphate pathway in health and diseases.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29282838
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383672
}}
* {{medline-title
|title=Integrin-linked kinase: A new actor in the ageing process?
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101014
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.10.026
}}
* {{medline-title
|title=Efficacy of a computer-based cognitive training program in older people with subjective memory complaints: a randomized study.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28316267
|full-text-url=https://sci-hub.do/10.1080/00207454.2017.1308930
}}
==IRF8==
 
* {{medline-title
|title=[[IRF8]] induces senescence of lung cancer cells to exert its tumor suppressive function.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31594449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927690
}}
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
* {{medline-title
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes.
|date=12.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941
}}
* {{medline-title
|title=Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26002684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503803
}}
==ITGA2B==
 
* {{medline-title
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
}}
* {{medline-title
|title=Plasma Amyloid Beta 1-42 and DNA Methylation Pattern Predict Accelerated Aging in Young Subjects with Down Syndrome.
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27234618
|full-text-url=https://sci-hub.do/10.1007/s12017-016-8413-y
}}
* {{medline-title
|title=Developing a DNA methylation assay for human age prediction in blood and bloodstain.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25979242
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2015.05.007
}}
* {{medline-title
|title=Aging of blood can be tracked by DNA methylation changes at just three CpG sites.
|date=03.02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24490752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053864
}}
==KCNB1==
 
* {{medline-title
|title=Oxidation of [[KCNB1]] potassium channels in the murine brain during aging is associated with cognitive impairment.
|date=14.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922570
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471606
}}
* {{medline-title
|title=Oxidation of [[KCNB1]] Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury.
|date=26.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27798188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098843
}}
* {{medline-title
|title=Oxidation of K( ) Channels in Aging and Neurodegeneration.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27114846
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809605
}}
* {{medline-title
|title=Oxidation of [[KCNB1]] K( ) channels in central nervous system and beyond.
|date=26.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24921000
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050120
}}
==KISS1==
 
* {{medline-title
|title=Kisspeptin level in the aging ovary is regulated by the sympathetic nervous system.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27856623
|full-text-url=https://sci-hub.do/10.1530/JOE-16-0181
}}
* {{medline-title
|title=Kisspeptin across the human lifespan:evidence from animal studies and beyond.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27340201
|full-text-url=https://sci-hub.do/10.1530/JOE-15-0538
}}
* {{medline-title
|title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460
}}
* {{medline-title
|title=[Profiles of reproduction-related mRNA expressions in hypothalamus of female mice with advancing age].
|date=17.12.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24548401
 
}}
==L1CAM==
 
* {{medline-title
|title=Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression.
|date=12.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31510944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739972
}}
* {{medline-title
|title=Induction, regulation and roles of neural adhesion molecule [[L1CAM]] in cellular senescence.
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615539
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892697
}}
* {{medline-title
|title=Cerebrospinal fluid biomarkers of infantile congenital hydrocephalus.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28212403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315300
}}
* {{medline-title
|title=Neuropsin Expression Correlates with Dendritic Marker MAP2c Level in Different Brain Regions of Aging Mice.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24965600
|full-text-url=https://sci-hub.do/10.1007/s12035-014-8780-z
}}
==LAMP1==
 
* {{medline-title
|title=Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain.
|date=24.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32579115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367682
}}
* {{medline-title
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|date=07.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
}}
* {{medline-title
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
}}
* {{medline-title
|title=Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease).
|date=15.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26450516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654058
}}
==LIF==
 
* {{medline-title
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity.
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174
}}
* {{medline-title
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.
|date=15.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304
}}
* {{medline-title
|title=Assaying human neutrophil elastase activity by capillary zone electrophoresis combined with laser-induced fluorescence.
|date=06.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26454788
|full-text-url=https://sci-hub.do/10.1016/j.chroma.2015.09.084
}}
* {{medline-title
|title=iPSCs, aging and age-related diseases.
|date=25.09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24784583
|full-text-url=https://sci-hub.do/10.1016/j.nbt.2014.04.004
}}
==LONP1==
 
* {{medline-title
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence.
|date=15.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833
}}
* {{medline-title
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068
}}
* {{medline-title
|title=Mitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disorders.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27387767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183306
}}
* {{medline-title
|title=Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer.
|date=10-12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27308364
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905204
}}
==MAOA==
 
* {{medline-title
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.
|date=05.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149
}}
* {{medline-title
|title=Age-dependent role of pre- and perinatal factors in interaction with genes on ADHD symptoms across adolescence.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28259004
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2017.02.014
}}
* {{medline-title
|title=Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24791650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163500
}}
* {{medline-title
|title=Investigation of association of serotonin transporter and monoamine oxidase-A genes with Alzheimer's disease and depression in the VITA study cohort: a 90-month longitudinal study.
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24443391
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32220
}}
==MAPKAPK2==
 
* {{medline-title
|title=Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks.
|date=03.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31801093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980792
}}
* {{medline-title
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
}}
* {{medline-title
|title=Rapamycin and the inhibition of the secretory phenotype.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28167236
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.01.026
}}
* {{medline-title
|title=Microwave-Assisted Synthesis of a MK2 Inhibitor by Suzuki-Miyaura Coupling for Study in Werner Syndrome Cells.
|date=03.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26046488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491660
}}
==MARCKS==
 
* {{medline-title
|title=Ser46-Phosphorylated [[MARCKS]] Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology.
|date=07-08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225354
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140116
}}
* {{medline-title
|title=[[MARCKS]] contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis.
|date=21.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27081703
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122339
}}
* {{medline-title
|title=[[MARCKS]]-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26010231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568964
}}
* {{medline-title
|title=The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release.
|date=10.02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348107
}}
==MCL1==
 
* {{medline-title
|title=[[MCL1]] gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30296359
|full-text-url=https://sci-hub.do/10.1002/iub.1944
}}
* {{medline-title
|title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
|date=10.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741
}}
* {{medline-title
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
}}
* {{medline-title
|title=[[RHEB]]: a potential regulator of chondrocyte phenotype for cartilage tissue regeneration.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27061379
|full-text-url=https://sci-hub.do/10.1002/term.2148
}}
==MCM2==
 
* {{medline-title
|title=Trophoblast type-specific expression of senescence markers in the human placenta.
|date=15.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327484
|full-text-url=https://sci-hub.do/10.1016/j.placenta.2019.06.377
}}
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
* {{medline-title
|title=Evaluation of Nestin Expression in the Developing and Adult Mouse Inner Ear.
|date=01.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27474107
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036354
}}
* {{medline-title
|title=A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation.
|date=04.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26337530
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559945
}}
==MTMR14==
 
* {{medline-title
|title=EDTP/[[MTMR14]]: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates.
|date=13.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31029679
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2019.04.053
}}
* {{medline-title
|title=Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster.
|date=16.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30528881
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.12.009
}}
* {{medline-title
|title=AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26312549
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835959
}}
* {{medline-title
|title=Novel excitation-contraction coupling related genes reveal aspects of muscle weakness beyond atrophy-new hopes for treatment of musculoskeletal diseases.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24600395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927072
}}
==NCL==
 
* {{medline-title
|title=Factors Affecting Microvascular Responses in the Bulbar Conjunctiva in Habitual Contact Lens Wearers.
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30098199
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088803
}}
* {{medline-title
|title=Small nucleoli are a cellular hallmark of longevity.
|date=30.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28853436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582349
}}
* {{medline-title
|title=Mesterolone treatment of aging male syndrome improves lower urinary tract symptoms.
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25842579
 
}}
* {{medline-title
|title=Retinal function in aging homozygous Cln3 (Δex7/8) knock-in mice.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24664736
|full-text-url=https://sci-hub.do/10.1007/978-1-4614-3209-8_63
}}
==NF1==
 
* {{medline-title
|title=The S[[NF1]] Kinase Ubiquitin-associated Domain Restrains Its Activation, Activity, and the Yeast Life Span.
|date=19.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25869125
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505455
}}
* {{medline-title
|title=[[NF1]] loss induces senescence during human melanocyte differentiation in an iPSC-based model.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824590
|full-text-url=https://sci-hub.do/10.1111/pcmr.12369
}}
* {{medline-title
|title=TGF-β/[[NF1]]/Smad4-mediated suppression of ANT2 contributes to oxidative stress in cellular senescence.
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25220407
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2014.08.029
}}
* {{medline-title
|title=Neuropsychological impairments in elderly Neurofibromatosis type 1 patients.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24556498
|full-text-url=https://sci-hub.do/10.1016/j.ejmg.2014.02.004
}}
==NLRC4==
 
* {{medline-title
|title=Hyperglycemia-induced inflamm-aging accelerates gingival senescence via [[NLRC4]] phosphorylation.
|date=06.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31676687
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901307
}}
* {{medline-title
|title=Contribution of the inflammasome to inflammaging.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30473634
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240324
}}
* {{medline-title
|title=Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28092664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320935
}}
* {{medline-title
|title=The Expression Changes of Inflammasomes in the Aging Rat Kidneys.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26219846
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888379
}}
==NPC2==
 
* {{medline-title
|title=Attenuation of the Niemann-Pick type [[C2]] disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29655638
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2018.04.001
}}
* {{medline-title
|title=Quantification of age-related changes of α-tocopherol in lysosomal membranes in murine tissues and human fibroblasts.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27095633
|full-text-url=https://sci-hub.do/10.1002/biof.1274
}}
* {{medline-title
|title=Systemic administration of 2-hydroxypropyl-β-cyclodextrin to symptomatic Npc1-deficient mice slows cholesterol sequestration in the major organs and improves liver function.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25115571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526211
}}
* {{medline-title
|title=Niemann-Pick C disease gene mutations and age-related neurodegenerative disorders.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24386122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875432
}}
==NRG1==
 
* {{medline-title
|title=Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis.
|date=29.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27469430
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965755
}}
* {{medline-title
|title=Neuregulin-1 Administration Protocols Sufficient for Stimulating Cardiac Regeneration in Young Mice Do Not Induce Somatic, Organ, or Neoplastic Growth.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27175488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866786
}}
* {{medline-title
|title=Neuregulin 1 improves glucose tolerance in adult and old rats.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26404652
|full-text-url=https://sci-hub.do/10.1016/j.diabet.2015.08.003
}}
* {{medline-title
|title=Disruption of hippocampal neuregulin 1-ErbB4 signaling contributes to the hippocampus-dependent cognitive impairment induced by isoflurane in aged mice.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589481
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062586
}}
==ORC1==
 
* {{medline-title
|title=The hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.
|date=11.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25874378
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358699
}}
* {{medline-title
|title=The role of T[[ORC1]] in muscle development in Drosophila.
|date=13.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25866192
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394354
}}
* {{medline-title
|title=mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25796566
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2015.03.014
}}
* {{medline-title
|title=Drug synergy drives conserved pathways to increase fission yeast lifespan.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786258
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364780
}}
==OXTR==
 
* {{medline-title
|title=Association of oxytocin levels and oxytocin receptor gene polymorphism (rs2254298) with cardiovascular risk factors in Brazilian elderly from Primary Health Care.
|date=09-10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31326852
|full-text-url=https://sci-hub.do/10.1016/j.archger.2019.103903
}}
* {{medline-title
|title=Impact of housing conditions on social behavior, neuroimmune markers, and oxytocin receptor expression in aged male and female Fischer 344 rats.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31100373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559851
}}
* {{medline-title
|title=Associations between oxytocin receptor gene ([[OXTR]]) methylation, plasma oxytocin, and attachment across adulthood.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29410310
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072619
}}
* {{medline-title
|title=DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor ([[BDNF]]) and oxytocin receptor ([[OXTR]]) genes are associated with anxiety/depression in older women.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26175754
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485183
}}
==PAK1==
 
* {{medline-title
|title=1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating [[PAK1]] at nM levels.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760342
|full-text-url=https://sci-hub.do/10.5582/ddt.2018.01018
}}
* {{medline-title
|title=From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic [[PAK1]]-blockers/longevity-promoters for cancer therapy.
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814374
|full-text-url=https://sci-hub.do/10.1016/j.ejmech.2017.07.043
}}
* {{medline-title
|title=Effect of Okinawa Propolis on [[PAK1]] Activity, Caenorhabditis elegans Longevity, Melanogenesis, and Growth of Cancer Cells.
|date=13.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27337169
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.6b01785
}}
* {{medline-title
|title=Several herbal compounds in Okinawa plants directly inhibit the oncogenic/aging kinase [[PAK1]].
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25639302
|full-text-url=https://sci-hub.do/10.5582/ddt.2014.01045
}}
==PARK7==
 
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
* {{medline-title
|title=The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28177569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334568
}}
* {{medline-title
|title=Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27288264
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993333
}}
* {{medline-title
|title=Life-time expression of the proteins peroxiredoxin, beta-synuclein, [[P[[AR]]K7]]/DJ-1, and stathmin in the primary visual and primary somatosensory cortices in rats.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25788877
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349188
}}
==PDC==
 
* {{medline-title
|title=The mitochondrial translocase of the inner membrane PaTim54 is involved in defense response and longevity in Podospora anserina.
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31351193
|full-text-url=https://sci-hub.do/10.1016/j.fgb.2019.103257
}}
* {{medline-title
|title=Neuron-specific knockdown of Drosophila [[PDHB]] induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting.
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501567
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.02.035
}}
* {{medline-title
|title=Assessing degradation of composite resin cements during artificial aging by Martens hardness.
|date=19.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28526054
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437403
}}
* {{medline-title
|title=Sevoflurane anesthesia induces neither contextual fear memory impairment nor alterations in local population connectivity of medial prefrontal cortex local field potentials networks in aged rats.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946081
|full-text-url=https://sci-hub.do/10.1111/fcp.12194
}}
==PDE4D==
 
* {{medline-title
|title=Phosphodiesterase [[PDE4D]] Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33192469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655962
}}
* {{medline-title
|title=Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function.
|date=02.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30409425
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.180
}}
* {{medline-title
|title=The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28438557
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2017.04.015
}}
* {{medline-title
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490
|full-text-url=https://sci-hub.do/10.1071/RD14472
}}
==PDF==
 
* {{medline-title
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models.
|date=28.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415
}}
* {{medline-title
|title=Drosophila Clock Is Required in Brain Pacemaker Neurons to Prevent Premature Locomotor Aging Independently of Its Circadian Function.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28072817
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224980
}}
* {{medline-title
|title=SnapShot: Neuronal Regulation of Aging.
|date=28.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27471972
|full-text-url=https://sci-hub.do/10.1016/j.cell.2016.07.022
}}
* {{medline-title
|title=Recent data on Mediterranean diet, cardiovascular disease, cancer, diabetes and life expectancy.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26084734
|full-text-url=https://sci-hub.do/10.4149/bll_2015_065
}}
==PFAS==
 
* {{medline-title
|title=Associations between serum concentrations of perfluoroalkyl substances and DNA methylation in women exposed through drinking water: A pilot study in Ronneby, Sweden.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33007577
|full-text-url=https://sci-hub.do/10.1016/j.envint.2020.106148
}}
* {{medline-title
|title=Perfluorinated alkyl substances impede growth, reproduction, lipid metabolism and lifespan in Daphnia magna.
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32521362
|full-text-url=https://sci-hub.do/10.1016/j.scitotenv.2020.139682
}}
* {{medline-title
|title=The effect of weathering on per- and polyfluoroalkyl substances ([[PFAS]]s) from durable water repellent (DWR) clothing.
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32062207
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2020.126100
}}
* {{medline-title
|title=Longitudinal measures of perfluoroalkyl substances (P[[FAS]]) in serum of Gullah African Americans in South Carolina: 2003-2013.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25819541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583839
}}
==PLAU==
 
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
* {{medline-title
|title=Functional networks of aging markers in the glomeruli of IgA nephropathy: a new therapeutic opportunity.
|date=07.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27127888
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085107
}}
==PNP==
 
* {{medline-title
|title=Temporal Discrimination Thresholds and Proprioceptive Performance: Impact of Age and Nerve Conduction.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31803012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877661
}}
* {{medline-title
|title=Polyneuropathy in Severely Obese Women Without Diabetes: Prevalence and Associated Factors.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30536202
|full-text-url=https://sci-hub.do/10.1007/s11695-018-03627-0
}}
* {{medline-title
|title=Electrophysiological evidence for preserved primacy of lexical prediction in aging.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29852201
|full-text-url=https://sci-hub.do/10.1016/j.neuropsychologia.2018.05.023
}}
* {{medline-title
|title=High prevalence of colonization of oral cavity by respiratory pathogens in frail older patients with oropharyngeal dysphagia.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416412
|full-text-url=https://sci-hub.do/10.1111/nmo.12690
}}
==POU5F1==
 
* {{medline-title
|title=Cell quality evaluation with gene expression analysis of spheroids (3D) and adherent (2D) adipose stem cells.
|date=24.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33148459
|full-text-url=https://sci-hub.do/10.1016/j.gene.2020.145269
}}
* {{medline-title
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853
}}
* {{medline-title
|title=Characterization of the [[POU5F1]] Homologue in Nile Tilapia: From Expression Pattern to Biological Activity.
|date=15.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27473876
|full-text-url=https://sci-hub.do/10.1089/scd.2016.0143
}}
* {{medline-title
|title=Determination phase at transition of gonocytes to spermatogonial stem cells improves establishment efficiency of spermatogonial stem cells in domestic cats.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26411537
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685225
}}
==PRC1==
 
* {{medline-title
|title=Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein [[BMI1]] in breast cancer cells.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986597
}}
* {{medline-title
|title=Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177687
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9737-1
}}
* {{medline-title
|title=The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27442247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956247
}}
* {{medline-title
|title=[[CBX7]] and miR-9 are part of an autoregulatory loop controlling p16(INK) (4a).
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416703
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693451
}}
==PREP==
 
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
* {{medline-title
|title=Mechanism of Action of Prolyl Oligopeptidase ([[PREP]]) in Degenerative Brain Diseases: Has Peptidase Activity Only a Modulatory Role on the Interactions of [[PREP]] with Proteins?
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28261087
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306367
}}
* {{medline-title
|title=Improving Pain Relief in Elder Patients (I-[[PREP]]): An Emergency Department Education and Quality Intervention.
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27806183
|full-text-url=https://sci-hub.do/10.1111/jgs.14377
}}
* {{medline-title
|title=Age and muscle-dependent variations in corticospinal excitability during standing tasks.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25310218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195709
}}
==PTGS2==
 
* {{medline-title
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism.
|date=21.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237
}}
* {{medline-title
|title=Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging.
|date=28.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198498
}}
* {{medline-title
|title=Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25329999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203852
}}
* {{medline-title
|title=Coordination of gene expression of arachidonic and docosahexaenoic acid cascade enzymes during human brain development and aging.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24963629
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070994
}}
==RBP4==
 
* {{medline-title
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats].
|date=08.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110
}}
* {{medline-title
|title=Transport of vitamin A across blood-tissue barriers is facilitated by [[STRA6]].
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27189978
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970611
}}
* {{medline-title
|title=[Adipose tissue, adipokines and aging].
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27000819
 
}}
* {{medline-title
|title=Transgenic Mice Overexpressing Serum Retinol-Binding Protein Develop Progressive Retinal Degeneration through a Retinoid-Independent Mechanism.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26055327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508322
}}
==REC8==
 
* {{medline-title
|title=Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667147
|full-text-url=https://sci-hub.do/10.1007/s11655-018-2835-3
}}
* {{medline-title
|title=The effect of DHEA on apoptosis and cohesin levels in oocytes in aged mice.
|date=12.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28717062
|full-text-url=https://sci-hub.do/10.5582/bst.2017.01108
}}
* {{medline-title
|title=Rec-8 dimorphism affects longevity, stress resistance and X-chromosome nondisjunction in C. elegans, and replicative lifespan in S. cerevisiae.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25136348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120681
}}
* {{medline-title
|title=Age-related decrease of meiotic cohesins in human oocytes.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24806359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013030
}}
==RHEB==
 
* {{medline-title
|title=The Rheb-TORC1 signaling axis functions as a developmental checkpoint.
|date=02.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063671
}}
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
}}
* {{medline-title
|title=CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in [i]C. elegans[/i].
|date=09.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29515755
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839386
}}
* {{medline-title
|title=[[RHEB]]: a potential regulator of chondrocyte phenotype for cartilage tissue regeneration.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27061379
|full-text-url=https://sci-hub.do/10.1002/term.2148
}}
==RPE65==
 
* {{medline-title
|title=Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30091312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085187
}}
* {{medline-title
|title=Age-related macular degeneration phenotypes are associated with increased tumor necrosis-alpha and subretinal immune cells in aged Cxcr5 knockout mice.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28282423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345864
}}
* {{medline-title
|title=The amino acid transporter [[SLC36A4]] regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28083894
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334531
}}
* {{medline-title
|title=Thinning of the [[RPE]] and choroid associated with T lymphocyte recruitment in aged and light-challenged mice.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26392743
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558476
}}
==SATB1==
 
* {{medline-title
|title=Loss of [[SATB1]] Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons.
|date=03.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31543366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493192
}}
* {{medline-title
|title=Transcriptomic analysis of human IL-7 receptor alpha  and  effector memory CD8  T cells reveals an age-associated signature linked to influenza vaccine response in older adults.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612637
}}
* {{medline-title
|title=Divergent [[SATB1]] expression across human life span and tissue compartments.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30803026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618325
}}
* {{medline-title
|title=Changes in expression of special AT-rich sequence binding protein 1 and phosphatase and tensin homologue in kidneys of diabetic rats during ageing.
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29506055
|full-text-url=https://sci-hub.do/10.1093/ndt/gfy003
}}
==SATB2==
 
* {{medline-title
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
}}
* {{medline-title
|title=[[SATB2]]-Nanog axis links age-related intrinsic changes of mesenchymal stem cells from craniofacial bone.
|date=14.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27632702
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076449
}}
* {{medline-title
|title=Transplantation of osteoporotic bone marrow stromal cells rejuvenated by the overexpression of [[SATB2]] prevents alveolar bone loss in ovariectomized rats.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27599698
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.09.001
}}
* {{medline-title
|title=Roles of [[SATB2]] in site-specific stemness, autophagy and senescence of bone marrow mesenchymal stem cells.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25200657
|full-text-url=https://sci-hub.do/10.1002/jcp.24792
}}
==SDC1==
 
* {{medline-title
|title=Olmesartan alleviates bleomycin-mediated vascular smooth muscle cell senescence via the miR-665/[[SDC1]] axis.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33042414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540088
}}
* {{medline-title
|title=Sulfated syndecan 1 is critical to preventing cellular senescence by modulating fibroblast growth factor receptor endocytosis.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32530114
|full-text-url=https://sci-hub.do/10.1096/fj.201902714R
}}
* {{medline-title
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
}}
* {{medline-title
|title=Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: the role of TGF-β.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27434331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032688
}}
==SF1==
 
* {{medline-title
|title=Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576894
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.12.034
}}
* {{medline-title
|title=Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans.
|date=05.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27919065
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361225
}}
* {{medline-title
|title=The cerebellum ages slowly according to the epigenetic clock.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26000617
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468311
}}
* {{medline-title
|title=Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice.
|date=30.09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25225411
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191810
}}
==SFRP1==
 
* {{medline-title
|title=[Role and alterations of DNA methylation during the aging and cancer].
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
}}
* {{medline-title
|title=Age-related increase in Wnt inhibitor causes a senescence-like phenotype in human cardiac stem cells.
|date=03.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28435069
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.04.110
}}
* {{medline-title
|title=Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma.
|date=21.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28058013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175245
}}
* {{medline-title
|title=The intrinsic stiffness of human trabecular meshwork cells increases with senescence.
|date=20.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25915531
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558157
}}
==SMN2==
 
* {{medline-title
|title=Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment.
|date=01.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589162
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819103
}}
* {{medline-title
|title=Type 0 Spinal Muscular Atrophy: Further Delineation of Prenatal and Postnatal Features in 16 Patients.
|date=29.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27911332
|full-text-url=https://sci-hub.do/10.3233/JND-160177
}}
* {{medline-title
|title=Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy.
|date=27.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27621445
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047168
}}
* {{medline-title
|title=Motor neuron disease. [[SMN2]] splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.
|date=08.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25104390
|full-text-url=https://sci-hub.do/10.1126/science.1250127
}}
==SP1==
 
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
* {{medline-title
|title=Downregulation of [[CITED2]] contributes to TGFβ-mediated senescence of tendon-derived stem cells.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28084522
|full-text-url=https://sci-hub.do/10.1007/s00441-016-2552-1
}}
* {{medline-title
|title=[[WNT1]]-induced Secreted Protein-1 (WI[[SP1]]), a Novel Regulator of Bone Turnover and Wnt Signaling.
|date=29.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25864198
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447973
}}
* {{medline-title
|title=Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase.
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25359865
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.114.303899
}}
==SPP1==
 
* {{medline-title
|title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781
}}
* {{medline-title
|title=Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence.
|date=28.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28105936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249001
}}
* {{medline-title
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853
}}
* {{medline-title
|title=Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26859687
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844783
}}
==SPR==
 
* {{medline-title
|title=Regulation of lifespan by neural excitation and REST.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31619788
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893853
}}
* {{medline-title
|title=How many geriatricians should, at minimum, be staffing health regions in Australia?
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171127
|full-text-url=https://sci-hub.do/10.1111/ajag.12467
}}
* {{medline-title
|title=Mutation of C. elegans demethylase spr-5 extends transgenerational longevity.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26691751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746603
}}
* {{medline-title
|title=[[REST]] and stress resistance in ageing and Alzheimer's disease.
|date=27.03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24670762
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110979
}}
==SPRY1==
 
* {{medline-title
|title=Sprouty1 Prevents Cellular Senescence Maintaining Proliferation and Differentiation Capacity of Human Adipose Stem/Progenitor Cells.
|date=13.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32304210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662188
}}
* {{medline-title
|title=Mechanism of [[SPRY1]] methylation regulating natural aging of skin epidermal cells.
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31483543
|full-text-url=https://sci-hub.do/10.1111/jocd.13126
}}
* {{medline-title
|title=MicroRNA-21 promotes glioma cell proliferation and inhibits senescence and apoptosis by targeting [[SPRY1]] via the [[PTEN]]/PI3K/AKT signaling pathway.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29316313
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489721
}}
* {{medline-title
|title=Age-Associated Methylation Suppresses [[SPRY1]], Leading to a Failure of Re-quiescence and Loss of the Reserve Stem Cell Pool in Elderly Muscle.
|date=10.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26526994
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2015.09.067
}}
==SRD5A2==
 
* {{medline-title
|title=Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II.
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32125089
|full-text-url=https://sci-hub.do/10.1111/jocd.13355
}}
* {{medline-title
|title=Epidemiological and Mendelian Randomization Studies of Dihydrotestosterone and Estradiol and Leukocyte Telomere Length in Men.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26789780
|full-text-url=https://sci-hub.do/10.1210/jc.2015-4139
}}
* {{medline-title
|title=DNA methyl transferase 1 reduces expression of [[SRD5A2]] in the aging adult prostate.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25700986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348471
}}
* {{medline-title
|title=Lessons learned about prostatic transformation from the age-related methylation of 5α-reductase type 2 gene.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25700984
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348462
}}
==STAR==
 
* {{medline-title
|title=Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs.
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28166986
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2016.11.007
}}
* {{medline-title
|title=Role of the steroidogenic acute regulatory protein in health and disease.
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26271515
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707056
}}
* {{medline-title
|title=Impact of acute geriatric care in elderly patients according to the Screening Tool of Older Persons' Prescriptions/Screening Tool to Alert doctors to Right Treatment criteria in northern France.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25809727
|full-text-url=https://sci-hub.do/10.1111/ggi.12474
}}
* {{medline-title
|title=[Polypharmacy to the elderly prevails].
|date=16.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786836
 
}}
==STH==
 
* {{medline-title
|title=Regional variation in Ascaris lumbricoides and Trichuris trichiura infections by age cohort and sex: effects of market integration among the indigenous Shuar of Amazonian Ecuador.
|date=24.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27884213
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123216
}}
* {{medline-title
|title=Koolen-de Vries Syndrome: Clinical Report of an Adult and Literature Review.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27852077
|full-text-url=https://sci-hub.do/10.1159/000452724
}}
* {{medline-title
|title=Heritability and factors associated with number of harness race starts in the Spanish Trotter horse population.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27566678
|full-text-url=https://sci-hub.do/10.1111/evj.12632
}}
* {{medline-title
|title=Can chemotherapy alone eliminate the transmission of soil transmitted helminths?
|date=10.06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24916278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079919
}}
==TBC1D1==
 
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
* {{medline-title
|title=Calorie restriction leads to greater Akt2 activity and glucose uptake by insulin-stimulated skeletal muscle from old rats.
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26739650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796740
}}
* {{medline-title
|title=Insulin Signaling and Glucose Uptake in the Soleus Muscle of 30-Month-Old Rats After Calorie Restriction With or Without Acute Exercise.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341783
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864161
}}
* {{medline-title
|title=Effects of sex and age on chicken [[TBC1D1]] gene mRNA expression.
|date=13.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26214451
|full-text-url=https://sci-hub.do/10.4238/2015.July.13.16
}}
==TBP==
 
* {{medline-title
|title=Trinucleotide repeat expansion of TATA-binding protein gene associated with Parkinson's disease: A Thai multicenter study.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27172828
|full-text-url=https://sci-hub.do/10.1016/j.parkreldis.2016.05.008
}}
* {{medline-title
|title=[[CALHM1]] Deletion in Mice Affects Glossopharyngeal Taste Responses, Food Intake, Body Weight, and Life Span.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25855639
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542651
}}
* {{medline-title
|title=Deactivation of [[TBP]] contributes to SCA17 pathogenesis.
|date=20.12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25104854
|full-text-url=https://sci-hub.do/10.1093/hmg/ddu410
}}
* {{medline-title
|title=Age-dependent decrease in chaperone activity impairs [[MANF]] expression, leading to Purkinje cell degeneration in inducible SCA17 mice.
|date=22.01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863472
}}
==TET1==
 
* {{medline-title
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
}}
* {{medline-title
|title=Epigenetic Co-Deregulation of [[EZH2]]/[[TET1]] is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30809307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376470
}}
* {{medline-title
|title=DNA Hydroxymethylation Levels Are Altered in Blood Cells From Down Syndrome Persons Enrolled in the MARK-AGE Project.
|date=09.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29069286
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946825
}}
* {{medline-title
|title=Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24746615
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410980
}}
==TLR8==
 
* {{medline-title
|title=[[TLR8]]-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy.
|date=08.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30344014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050437
}}
* {{medline-title
|title=Controlling T cell senescence in the tumor microenvironment for tumor immunotherapy.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25949919
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404789
}}
* {{medline-title
|title=Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834936
|full-text-url=https://sci-hub.do/10.1016/j.patbio.2015.03.002
}}
* {{medline-title
|title=[[TLR8]] signaling enhances tumor immunity by preventing tumor-induced T-cell senescence.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25231413
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287933
}}
==TNNT3==
 
* {{medline-title
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|date=06.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
}}
* {{medline-title
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179
}}
* {{medline-title
|title=Effects of age and hindlimb immobilization and remobilization on fast troponin T precursor mRNA alternative splicing in rat gastrocnemius muscle.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26799695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876695
}}
* {{medline-title
|title=Influence of ageing and essential amino acids on quantitative patterns of troponin T alternative splicing in human skeletal muscle.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26201856
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527890
}}
==TSC1==
 
* {{medline-title
|title=mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30924297
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516169
}}
* {{medline-title
|title=[[FTO]] is involved in Alzheimer's disease by targeting [[TSC1]]-mTOR-Tau signaling.
|date=25.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501742
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.02.201
}}
* {{medline-title
|title=Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29023667
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716871
}}
* {{medline-title
|title=Moderate lifelong overexpression of tuberous sclerosis complex 1 ([[TSC1]]) improves health and survival in mice.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28400571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429778
}}
==TTL==
 
* {{medline-title
|title=Longitudinal Associations of Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio with Biomarkers of Oxidative Stress in Older Adults: Results of a Large Cohort Study.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31986512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098284
}}
* {{medline-title
|title=Evidence for the free radical/oxidative stress theory of ageing from the CHANCES consortium: a meta-analysis of individual participant data.
|date=15.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26666526
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678534
}}
* {{medline-title
|title=Role of the serotonin transporter gene locus in the response to S[[SRI]] treatment of major depressive disorder in late life.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25827644
|full-text-url=https://sci-hub.do/10.1177/0269881115578159
}}
* {{medline-title
|title=Oxidative stress markers and all-cause mortality at older age: a population-based cohort study.
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25070660
|full-text-url=https://sci-hub.do/10.1093/gerona/glu111
}}
==TXNRD1==
 
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
* {{medline-title
|title=Mitochondrial thioredoxin reductase 2 is elevated in long-lived primate as well as rodent species and extends fly mean lifespan.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28474396
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506402
}}
* {{medline-title
|title=Antioxidants and Quality of Aging: Further Evidences for a Major Role of [[TXNRD1]] Gene Variability on Physical Performance at Old Age.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26064428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429211
}}
* {{medline-title
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201
}}
==VCAM1==
 
* {{medline-title
|title=Sunitinib facilitates metastatic breast cancer spreading by inducing endothelial cell senescence.
|date=29.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32993785
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526390
}}
* {{medline-title
|title=Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell [[VCAM1]].
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31086348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642642
}}
* {{medline-title
|title=Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and [[APOE]] genotype in cognitively normal adults.
|date=03.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28673336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496132
}}
* {{medline-title
|title=Endothelial Notch1 Activity Facilitates Metastasis.
|date=13.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28238683
|full-text-url=https://sci-hub.do/10.1016/j.ccell.2017.01.007
}}
==VHL==
 
* {{medline-title
|title=Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a [[VHL]]-1-independent transcriptional response.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399915
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00194-0
}}
* {{medline-title
|title=The Energy Maintenance Theory of Aging: Maintaining Energy Metabolism to Allow Longevity.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29901833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314662
}}
* {{medline-title
|title=Shorter telomere length increases age-related tumor risks in von Hippel-Lindau disease patients.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28776935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603836
}}
* {{medline-title
|title=Biological and clinical impact of hemangioblastoma-associated peritumoral cysts in von Hippel-Lindau disease.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26517769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818154
}}
==WNT1==
 
* {{medline-title
|title=Plasma proteomic profile of age, health span, and all-cause mortality in older adults.
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33089916
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681045
}}
* {{medline-title
|title=Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.
|date=07.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30686765
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6408230
}}
* {{medline-title
|title=Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.
|date=07.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30404864
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aau7137
}}
* {{medline-title
|title=[[WNT1]]-induced Secreted Protein-1 (WI[[SP1]]), a Novel Regulator of Bone Turnover and Wnt Signaling.
|date=29.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25864198
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447973
}}
==XPA==
 
* {{medline-title
|title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141
}}
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
* {{medline-title
|title=Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans.
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28934497
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766164
}}
* {{medline-title
|title=Defective mitophagy in [[XPA]] via PARP-1 hyperactivation and NAD( )/[[SIRT1]] reduction.
|date=08.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24813611
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625837
}}
==XRCC4==
 
* {{medline-title
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081
}}
* {{medline-title
|title=Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans.
|date=01.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071568
}}
* {{medline-title
|title=The impact of statins on biological characteristics of stem cells provides a novel explanation for their pleiotropic beneficial and adverse clinical effects.
|date=15.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26224580
|full-text-url=https://sci-hub.do/10.1152/ajpcell.00406.2014
}}
* {{medline-title
|title=Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25678531
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359693
}}
==ZEB1==
 
* {{medline-title
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
}}
* {{medline-title
|title=Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating [[DNMT1]] via [[ZEB1]].
|date=16.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29466247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842848
}}
* {{medline-title
|title=p16  induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27596953
|full-text-url=https://sci-hub.do/10.1002/mc.22564
}}
* {{medline-title
|title=The [[ZEB1]] transcription factor acts in a negative feedback loop with miR200 downstream of Ras and Rb1 to regulate Bmi1 expression.
|date=14.02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24371144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924277
}}
==A2M==
 
* {{medline-title
|title=Age-Dependent Variation in Glycosylation Features of Alpha-2-Macroglobulin.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31489526
|full-text-url=https://sci-hub.do/10.1007/s12013-019-00883-4
}}
* {{medline-title
|title=[[MMP2]]-[[A2M]] interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction.
|date=19.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29464020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814160
}}
* {{medline-title
|title=[[SPARCL1]] Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934753
}}
==AANAT==
 
* {{medline-title
|title=Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis.
|date=01.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993622
}}
* {{medline-title
|title=Morphofunctional and signaling molecules overlap of the pineal gland and thymus: role and significance in aging.
|date=15.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26943046
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914262
}}
* {{medline-title
|title=Comparison of arylalkylamine N-acetyltransferase and melatonin receptor type 1B immunoreactivity between young adult and aged canine spinal cord.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24962405
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178134
}}
==ABCB1==
 
* {{medline-title
|title=Paclitaxel-induced sensory peripheral neuropathy is associated with an [[ABCB1]] single nucleotide polymorphism and older age in Japanese.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28447211
|full-text-url=https://sci-hub.do/10.1007/s00280-017-3314-9
}}
* {{medline-title
|title=Relationship between mRNA expression levels of [[CYP3A4]], [[CYP3A5]] and SXR in peripheral mononuclear blood cells and aging in young kidney transplant recipients under tacrolimus treatment.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25916520
|full-text-url=https://sci-hub.do/10.2217/pgs.15.18
}}
* {{medline-title
|title=Vascular and extravascular distribution of the ATP-binding cassette transporters [[ABCB1]] and ABCC1 in aged human brain and pituitary.
|date=11-12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25218792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310818
}}
==ACO1==
 
* {{medline-title
|title=Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine.
|date=24.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30690072
|full-text-url=https://sci-hub.do/10.1016/j.jep.2019.01.019
}}
* {{medline-title
|title=Analysis of nodule senescence in pea (Pisum sativum L.) using laser microdissection, real-time PCR, and ACC immunolocalization.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28242415
|full-text-url=https://sci-hub.do/10.1016/j.jplph.2017.01.012
}}
* {{medline-title
|title=The Persimmon 9-lipoxygenase Gene DkLOX3 Plays Positive Roles in Both Promoting Senescence and Enhancing Tolerance to Abiotic Stress.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26697033
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674570
}}
==AGT==
 
* {{medline-title
|title=SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence.
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441382
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469683
}}
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
* {{medline-title
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632
}}
==AGTR1==
 
* {{medline-title
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632
}}
* {{medline-title
|title=Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age.
|date=01.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25124854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329281
}}
* {{medline-title
|title=Impact of the [[AGTR1]] A1166C polymorphism on subcortical hyperintensities and cognition in healthy older adults.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24981111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150909
}}
==ALK==
 
* {{medline-title
|title=Catalog of Lung Cancer Gene Mutations Among Chinese Patients.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850378
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417348
}}
* {{medline-title
|title=Age-related expression of TGF beta family receptors in human cumulus oophorus cells.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28466233
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581779
}}
* {{medline-title
|title=GBM-associated mutations and altered protein expression are more common in young patients.
|date=25.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491
}}
==APLP2==
 
* {{medline-title
|title=Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362021
|full-text-url=https://sci-hub.do/10.1007/s11064-018-2669-6
}}
* {{medline-title
|title=Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics.
|date=08.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27267879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897877
}}
* {{medline-title
|title=Combined deletions of amyloid precursor protein and amyloid precursor-like protein 2 reveal different effects on mouse brain metal homeostasis.
|date=03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24448592
|full-text-url=https://sci-hub.do/10.1039/c3mt00358b
}}
==APOA1==
 
* {{medline-title
|title=Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29623474
|full-text-url=https://sci-hub.do/10.1007/s10534-018-0101-y
}}
* {{medline-title
|title=Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans.
|date=06.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26337083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745765
}}
* {{medline-title
|title=DNA methylation in the apolipoprotein-A1 gene is associated with episodic memory performance in healthy older individuals.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25261444
|full-text-url=https://sci-hub.do/10.3233/JAD-141314
}}
==APOA5==
 
* {{medline-title
|title=Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30700132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399473
}}
* {{medline-title
|title=Longitudinal interaction between [[APOA5]] -1131T>C and overweight in the acceleration of age-related increase in arterial stiffness through the regulation of circulating triglycerides.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451986
|full-text-url=https://sci-hub.do/10.1038/s41440-018-0137-y
}}
* {{medline-title
|title=Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24917880
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042684
}}
==APOC3==
 
* {{medline-title
|title=Positional Obstructive Sleep Apnea Syndrome in Elderly Patients.
|date=10.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32050596
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042812
}}
* {{medline-title
|title=No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709
}}
* {{medline-title
|title=Nutritional habits, lifestyle, and genetic predisposition in cardiovascular and metabolic traits in Turkish population.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26856649
|full-text-url=https://sci-hub.do/10.1016/j.nut.2015.12.027
}}
==AQP5==
 
* {{medline-title
|title=Submandibular gland-specific inflammaging-induced hyposalivation in the male senescence-accelerated mouse prone -1 line (SAM-P1).
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684147
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09797-3
}}
* {{medline-title
|title=Investigation of age-related changes in the expression of aquaporin-1 and aquaporin-5 in the salivary glands of mice.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27067150
|full-text-url=https://sci-hub.do/10.3109/00016489.2016.1165353
}}
* {{medline-title
|title=Combinations of differentiation markers distinguish subpopulations of alveolar epithelial cells in adult lung.
|date=15.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26545903
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719049
}}
==AREG==
 
* {{medline-title
|title=Targeting amphiregulin ([[AREG]]) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31493351
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826133
}}
* {{medline-title
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
}}
* {{medline-title
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490
|full-text-url=https://sci-hub.do/10.1071/RD14472
}}
==ARHGAP18==
 
* {{medline-title
|title=Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma
|date=18.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863019
}}
* {{medline-title
|title=Caveolae control the anti-inflammatory phenotype of senescent endothelial cells.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25407919
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326911
}}
* {{medline-title
|title=Transcript profile of cellular senescence-related genes in Fuchs endothelial corneal dystrophy.
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25311168
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259834
}}
==ARID1A==
 
* {{medline-title
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|full-text-url=https://sci-hub.do/10.1002/path.5314
}}
* {{medline-title
|title=[[ARID1A]] suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[[[CDKN2A]]]] regulatory axis.
|date=18.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942143
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.099
}}
* {{medline-title
|title=The Chromatin Remodeling Component Arid1a Is a Suppressor of Spontaneous Mammary Tumors in Mice.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27280691
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981264
}}
==ATG3==
 
* {{medline-title
|title=Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells.
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32244623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235898
}}
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
* {{medline-title
|title=Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging.
|date=26.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28238968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361683
}}
==BAK1==
 
* {{medline-title
|title=Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon.
|date=23.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32710818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529960
}}
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
* {{medline-title
|title=The dominant negative [[AR]]M domain uncovers multiple functions of PUB13 in Arabidopsis immunity, flowering, and senescence.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449551
}}
==BATF==
 
* {{medline-title
|title=LncRNA-ES3 inhibition by Bhlhe40 is involved in high glucose-induced calcification/senescence of vascular smooth muscle cells.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32483833
|full-text-url=https://sci-hub.do/10.1111/nyas.14381
}}
* {{medline-title
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
}}
* {{medline-title
|title=Transcriptomic analysis of human IL-7 receptor alpha  and  effector memory CD8  T cells reveals an age-associated signature linked to influenza vaccine response in older adults.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612637
}}
==BECN1==
 
* {{medline-title
|title=Calpain-dependent Beclin1 cleavage stimulates senescence-associated cell death in HT22 hippocampal cells under the oxidative stress conditions.
|date=14.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30807795
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2019.02.036
}}
* {{medline-title
|title=Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-[[ULK1]] signaling pathway.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344647
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810242
}}
* {{medline-title
|title=Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo.
|date=03.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26098646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615103
}}
==BGN==
 
* {{medline-title
|title=Alterations of local functional connectivity in lifespan: A resting-state fMRI study.
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32462815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375100
}}
* {{medline-title
|title=Exploring variability in basal ganglia connectivity with functional MRI in healthy aging.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29442271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302142
}}
* {{medline-title
|title=Age-dependent changes in inflammation and extracellular matrix in bovine oviduct epithelial cells during the post-ovulatory phase.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27580129
|full-text-url=https://sci-hub.do/10.1002/mrd.22693
}}
==BMP15==
 
* {{medline-title
|title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012
|full-text-url=https://sci-hub.do/10.1002/mrd.23079
}}
* {{medline-title
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|date=18.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
}}
* {{medline-title
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490
|full-text-url=https://sci-hub.do/10.1071/RD14472
}}
==BMP6==
 
* {{medline-title
|title=Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology.
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233090
}}
* {{medline-title
|title=Cyp1b1 deletion and retinol deficiency coordinately suppress mouse liver lipogenic genes and hepcidin expression during post-natal development.
|date=15.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28583802
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985816
}}
* {{medline-title
|title=Age-dependent shifts in renal response to injury relate to altered [[BMP6]]/CTGF expression and signaling.
|date=01.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27558559
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00324.2016
}}
==BMP7==
 
* {{medline-title
|title=Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting [[BMP7]].
|date=11.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31829291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907335
}}
* {{medline-title
|title=TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27696331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233610
}}
* {{medline-title
|title=Effects of Usag-1 and Bmp7 deficiencies on murine tooth morphogenesis.
|date=13.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27178071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866418
}}
==BMPR2==
 
* {{medline-title
|title=Centenarians Overexpress Pluripotency-Related Genes.
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
}}
* {{medline-title
|title=Age-related expression of TGF beta family receptors in human cumulus oophorus cells.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28466233
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581779
}}
* {{medline-title
|title=Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26076038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496295
}}
==BSN==
 
* {{medline-title
|title=Nurses' perspectives: hospitalized older patients and end-of-life decision-making.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25892177
|full-text-url=https://sci-hub.do/10.1111/nicc.12125
}}
* {{medline-title
|title=Buddhist social networks and health in old age: A study in central Thailand.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25496203
|full-text-url=https://sci-hub.do/10.1111/ggi.12421
}}
* {{medline-title
|title=Retaining the wisdom: Academic nurse leaders' reflections on extending the working life of aging nurse faculty.
|date=01-02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24503313
|full-text-url=https://sci-hub.do/10.1016/j.profnurs.2013.06.012
}}
==CAPS==
 
* {{medline-title
|title=The Effect of Aging on the Ventilatory Response to Wearing a Chemical, Biological, Radiological, and Nuclear Hood Respirator at Rest and During Mild Exercise.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28051970
|full-text-url=https://sci-hub.do/10.7205/MILMED-D-16-00151
}}
* {{medline-title
|title=[Human bioaging acceleration as Chernobyl radiation consequence].
|date=11-12.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25486744
 
}}
* {{medline-title
|title=[Adaptation of self-image level and defense mechanisms in elderly patients with complicated stoma].
|date=11-12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25240989
|full-text-url=https://sci-hub.do/10.1016/j.enfcli.2014.07.006
}}
==CARM1==
 
* {{medline-title
|title=[[CARM1]] regulates senescence during airway epithelial cell injury in COPD pathogenesis.
|date=01.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31461302
|full-text-url=https://sci-hub.do/10.1152/ajplung.00441.2018
}}
* {{medline-title
|title=Nuclear AMPK regulated [[CARM1]] stabilization impacts autophagy in aged heart.
|date=29.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28315332
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.03.053
}}
* {{medline-title
|title=Coactivator-Associated Arginine Methyltransferase-1 Function in Alveolar Epithelial Senescence and Elastase-Induced Emphysema Susceptibility.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25906418
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455466
}}
==CASS4==
 
* {{medline-title
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
==CCN3==
 
* {{medline-title
|title=[[CCN3]] Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304321
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701218
}}
* {{medline-title
|title=[[CCN3]] (NOV) Drives Degradative Changes in Aging Articular Cartilage.
|date=13.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066270
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593953
}}
* {{medline-title
|title=[[CCN1]] (CYR61) and [[CCN3]] (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties.
|date=03.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26744771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853050
}}
==CCNA2==
 
* {{medline-title
|title=Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan.
|date=31.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881094
}}
* {{medline-title
|title=Cyclin A2 promotes DNA repair in the brain during both development and aging.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27425845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993346
}}
* {{medline-title
|title=PIM-1 modulates cellular senescence and links IL-6 signaling to heterochromatin formation.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25040935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331745
}}
==CCNB1==
 
* {{medline-title
|title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012
|full-text-url=https://sci-hub.do/10.1002/mrd.23079
}}
* {{medline-title
|title=Effect of [[CCNB1]] silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30069972
|full-text-url=https://sci-hub.do/10.1002/jcp.26816
}}
* {{medline-title
|title=Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan.
|date=31.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881094
}}
==CCR3==
 
* {{medline-title
|title=Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro.
|date=04.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32033185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036885
}}
* {{medline-title
|title=Early life allergen and air pollutant exposures alter longitudinal blood immune profiles in infant rhesus monkeys.
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28529118
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535809
}}
* {{medline-title
|title=An emerging role for eotaxins in neurodegenerative disease.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27664933
|full-text-url=https://sci-hub.do/10.1016/j.clim.2016.09.010
}}
==CCR4==
 
* {{medline-title
|title=mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and [[PAPPA]]-KO mice.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27618784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242303
}}
* {{medline-title
|title=Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27190305
|full-text-url=https://sci-hub.do/10.1189/jlb.5A0116-025R
}}
* {{medline-title
|title=[[CCR4]]  Regulatory T Cells Accumulate in the Very Elderly and Correlate With Superior 8-Year Survival.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25852090
|full-text-url=https://sci-hub.do/10.1093/gerona/glu128
}}
==CD200==
 
* {{medline-title
|title=Age exacerbates surgery-induced cognitive impairment and neuroinflammation in Sprague-Dawley rats: the role of IL-4.
|date=15.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28414034
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2017.04.004
}}
* {{medline-title
|title=Prior stressor exposure delays the recovery of surgery-induced cognitive impairment and prolongs neuroinflammation in aged rats.
|date=01.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27487302
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2016.07.045
}}
* {{medline-title
|title=Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating [[CD200]]-[[CD200]]R interaction involve the cannabinoid system.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24588829
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157566
}}
==CD81==
 
* {{medline-title
|title=Ovarian aging increases small extracellular vesicle [[CD81]]  release in human follicular fluid and influences miRNA profiles.
|date=17.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343446
}}
* {{medline-title
|title=Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature.
|date=15.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32326435
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227017
}}
* {{medline-title
|title=Increased production of functional small extracellular vesicles in senescent endothelial cells.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32101370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176858
}}
==CEL==
 
* {{medline-title
|title=Nanocarrier-Mediated Chemo-Immunotherapy Arrested Cancer Progression and Induced Tumor Dormancy in Desmoplastic Melanoma.
|date=28.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30016071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115293
}}
* {{medline-title
|title=An advanced glycation endproduct (AGE)-rich diet promotes accumulation of AGEs in Achilles tendon.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28336820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371572
}}
* {{medline-title
|title=Biological Effects Induced by Specific Advanced Glycation End Products in the Reconstructed Skin Model of Aging.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26309782
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497626
}}
==CFB==
 
* {{medline-title
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye.
|date=13.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230
}}
* {{medline-title
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
* {{medline-title
|title=Genetic factors associated with the development of age-related macular degeneration.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27170480
|full-text-url=https://sci-hub.do/10.1016/j.medici.2016.02.004
}}
==CHAT==
 
* {{medline-title
|title=Satisfaction and Technology Evaluation of a Telehealth Robotic Program to Optimize Healthy Independent Living for Older Adults.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320967
|full-text-url=https://sci-hub.do/10.1111/jnu.12436
}}
* {{medline-title
|title=Reliability of the Language ENvironment Analysis system (LENA™) in European French.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26174716
|full-text-url=https://sci-hub.do/10.3758/s13428-015-0634-8
}}
* {{medline-title
|title=Age-related gene expression analysis in enteric ganglia of human colon after laser microdissection.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25360110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197768
}}
==CISD2==
 
* {{medline-title
|title=[[CISD2]] Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells-As a Potential Therapeutic Target for Neurodegenerative Dementia.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33005144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479185
}}
* {{medline-title
|title=Protective Effects of [[CISD2]] and Influence of Curcumin on [[CISD2]] Expression in Aged Animals and Inflammatory Cell Model.
|date=25.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30934593
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470567
}}
* {{medline-title
|title=Cisd2 mediates lifespan: is there an interconnection among Ca²⁺ homeostasis, autophagy, and lifespan?
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24974737
|full-text-url=https://sci-hub.do/10.3109/10715762.2014.936431
}}
==COL1A2==
 
* {{medline-title
|title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts.
|date=01.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944
}}
* {{medline-title
|title=Genetic variants associated with skin aging in the Chinese Han population.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28057405
|full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2016.12.017
}}
* {{medline-title
|title=Effects of aging and uninephrectomy on renal changes in Tsukuba hypertensive mice.
|date=05.2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24648949
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917043
}}
==COL3A1==
 
* {{medline-title
|title=Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season.
|date=21.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31864349
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925900
}}
* {{medline-title
|title=Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890563
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553930
}}
* {{medline-title
|title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts.
|date=01.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944
}}
==COL6A1==
 
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
* {{medline-title
|title=Genome-wide DNA methylation profiles reveal novel candidate genes associated with meat quality at different age stages in hens.
|date=05.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28378745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381223
}}
* {{medline-title
|title=Bethlem myopathy: long-term follow-up identifies COL6 mutations predicting severe clinical evolution.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25535305
|full-text-url=https://sci-hub.do/10.1136/jnnp-2013-307245
}}
==CPT1C==
 
* {{medline-title
|title=Carnitine palmitoyltransferase 1C reverses cellular senescence of MRC-5 fibroblasts via regulating lipid accumulation and mitochondrial function.
|date=02.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32632982
|full-text-url=https://sci-hub.do/10.1002/jcp.29906
}}
* {{medline-title
|title=Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence.
|date=14.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32289751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202531
}}
* {{medline-title
|title=Effects of carnitine palmitoyltransferases on cancer cellular senescence.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30070697
|full-text-url=https://sci-hub.do/10.1002/jcp.27042
}}
==CRY2==
 
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
* {{medline-title
|title=Role of Aging and Hippocampus in Time-Place Learning: Link to Episodic-Like Memory?
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26834595
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717310
}}
* {{medline-title
|title=Association of osteoporosis with genetic variants of circadian genes in Chinese geriatrics.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26564225
|full-text-url=https://sci-hub.do/10.1007/s00198-015-3391-8
}}
==CTC1==
 
* {{medline-title
|title=[[CTC1]]-[[STN1]] coordinates G- and C-strand synthesis to regulate telomere length.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479
}}
* {{medline-title
|title=Stimulation of cell proliferation by glutathione monoethyl ester in aged bone marrow stromal cells is associated with the assistance of [[TERT]] gene expression and telomerase activity.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27251157
|full-text-url=https://sci-hub.do/10.1007/s11626-016-0021-5
}}
* {{medline-title
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
==CTH==
 
* {{medline-title
|title=Anterior Cingulate Structure and Perfusion is Associated with Cerebrospinal Fluid Tau among Cognitively Normal Older Adult APOEɛ4 Carriers.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31743999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310575
}}
* {{medline-title
|title=Curious CXR.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31320335
|full-text-url=https://sci-hub.do/10.1136/emermed-2019-208453
}}
* {{medline-title
|title=Mechanochemical Catalytic Transfer Hydrogenation of Aromatic Nitro Derivatives.
|date=30.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30513686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321105
}}
==CTLA4==
 
* {{medline-title
|title=Horticultural Therapy Reduces Biomarkers of Immunosenescence and Inflammaging in Community-Dwelling Older Adults: A Feasibility Pilot Randomized Controlled Trial.
|date=18.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33070170
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa271
}}
* {{medline-title
|title=[Efficacy and toxicity of immune checkpoint inhibitors in elderly patients - 5th edition of the congress of pharmacology of anticancer drugs].
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30471959
|full-text-url=https://sci-hub.do/10.1016/j.bulcan.2018.10.004
}}
* {{medline-title
|title=Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27190305
|full-text-url=https://sci-hub.do/10.1189/jlb.5A0116-025R
}}
==CXCL11==
 
* {{medline-title
|title=Endothelial cells under therapy-induced senescence secrete [[CXCL11]], which increases aggressiveness of breast cancer cells.
|date=10.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659248
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2020.06.019
}}
* {{medline-title
|title=Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity.
|date=13.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30867067
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417215
}}
* {{medline-title
|title=[Signal molecules of endometrium: gerontological and general pathhological aspects].
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28509480
 
}}
==CXCL13==
 
* {{medline-title
|title=RNA-seq data from C-X-C chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32642521
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334305
}}
* {{medline-title
|title=Structural and functional changes to lymph nodes in ageing mice.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28207940
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418465
}}
* {{medline-title
|title=Artery Tertiary Lymphoid Organs: Powerhouses of Atherosclerosis Immunity.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27777573
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056324
}}
==CXCL16==
 
* {{medline-title
|title=[[CXCR6]] Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and [[CD4]]  T-Cell-Dependent Control of Senescence.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710528
|full-text-url=https://sci-hub.do/10.1053/j.gastro.2019.01.247
}}
* {{medline-title
|title=Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate.
|date=09.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441728
}}
* {{medline-title
|title=Age-related alterations in blood and colonic dendritic cell properties.
|date=15.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26942871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914258
}}
==CXCL5==
 
* {{medline-title
|title=Hassall's corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus.
|date=05.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534943
|full-text-url=https://sci-hub.do/10.1093/intimm/dxy073
}}
* {{medline-title
|title=Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891542
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105902
}}
* {{medline-title
|title=Simultaneous time course analysis of multiple markers based on DNA microarray in incised wound in skeletal muscle for wound aging.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27376479
|full-text-url=https://sci-hub.do/10.1016/j.forsciint.2016.06.027
}}
==CXCR5==
 
* {{medline-title
|title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses.
|date=17.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542
}}
* {{medline-title
|title=Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27190305
|full-text-url=https://sci-hub.do/10.1189/jlb.5A0116-025R
}}
* {{medline-title
|title=Trafficking phenotype and production of granzyme B by double negative B cells (IgG( )IgD(-)CD27(-)) in the elderly.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24389059
|full-text-url=https://sci-hub.do/10.1016/j.exger.2013.12.011
}}
==CYLD==
 
* {{medline-title
|title=Premature aging and cancer development in transgenic mice lacking functional [[CYLD]].
|date=10.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30631004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339805
}}
* {{medline-title
|title=Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis.
|date=22.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554661
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.12.025
}}
* {{medline-title
|title=Elevated A20 contributes to age-dependent macrophage dysfunction in the lungs.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24440463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989429
}}
==CYP19A1==
 
* {{medline-title
|title=Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923019
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.016
}}
* {{medline-title
|title=Epidemiological and Mendelian Randomization Studies of Dihydrotestosterone and Estradiol and Leukocyte Telomere Length in Men.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26789780
|full-text-url=https://sci-hub.do/10.1210/jc.2015-4139
}}
* {{medline-title
|title=Compensatory Increase in Ovarian Aromatase in Older Regularly Cycling Women.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26126208
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570155
}}
==CYP1A1==
 
* {{medline-title
|title=Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31522824
|full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2019.08.010
}}
* {{medline-title
|title=Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in [[CYP1A1]]-overexpressing breast cancer cells.
|date=15.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448188
|full-text-url=https://sci-hub.do/10.1016/j.bmc.2018.11.013
}}
* {{medline-title
|title=Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures.
|date=25.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25795400
|full-text-url=https://sci-hub.do/10.1016/j.tiv.2015.03.005
}}
==CYP1B1==
 
* {{medline-title
|title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3
}}
* {{medline-title
|title=Target disruption of ribosomal protein pNO40 accelerates aging and impairs osteogenic differentiation of mesenchymal stem cells.
|date=22.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26721440
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.12.003
}}
* {{medline-title
|title=Expression of genes for AhR and Nrf2 signal pathways in the retina of OXYS rats during the development of retinopathy and melatonin-induced changes in this process.
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25110076
|full-text-url=https://sci-hub.do/10.1007/s10517-014-2582-1
}}
==CYP27B1==
 
* {{medline-title
|title=Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance.
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955863
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693043
}}
* {{medline-title
|title=Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism.
|date=22.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823
}}
* {{medline-title
|title=Environmental and genetic determinants of vitamin D status among older adults in London, UK.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26776442
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2016.01.005
}}
==CYP2C9==
 
* {{medline-title
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442
}}
* {{medline-title
|title=Determination of Human Hepatic [[CYP2C8]] and [[CYP1A2]] Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28228413
|full-text-url=https://sci-hub.do/10.1124/dmd.116.074583
}}
* {{medline-title
|title=Genotype-based dosage of acenocoumarol in highly-sensitive geriatric patients.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25669612
|full-text-url=https://sci-hub.do/10.5414/CP202206
}}
==CYP2J2==
 
* {{medline-title
|title=The effects of endothelium-specific [[CYP2J2]] overexpression on the attenuation of retinal ganglion cell apoptosis in a glaucoma rat model.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31295013
|full-text-url=https://sci-hub.do/10.1096/fj.201900756R
}}
* {{medline-title
|title=Regional vulnerability to lipoxidative damage and inflammation in normal human brain aging.
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30077575
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.023
}}
* {{medline-title
|title=Endothelium-specific [[CYP2J2]] overexpression attenuates age-related insulin resistance.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29318723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847864
}}
==CYP2R1==
 
* {{medline-title
|title=Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance.
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955863
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693043
}}
* {{medline-title
|title=Environmental and genetic determinants of vitamin D status among older adults in London, UK.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26776442
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2016.01.005
}}
* {{medline-title
|title=Late-onset hypogonadism: beyond testosterone.
|date=03-04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25248651
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650463
}}
==CYP7A1==
 
* {{medline-title
|title=Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396457
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681801
}}
* {{medline-title
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio).
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128
}}
* {{medline-title
|title=Synergic hypocholesterolaemic effect of n-3 PUFA and oestrogen by modulation of hepatic cholesterol metabolism in female rats.
|date=14.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26388416
|full-text-url=https://sci-hub.do/10.1017/S0007114515003517
}}
==DAP==
 
* {{medline-title
|title=Examining changes in the equity of physician distribution in Japan: a specialty-specific longitudinal study.
|date=08.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29317415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781009
}}
* {{medline-title
|title=Evaluation of organ and effective doses during paediatric barium meal examinations using PCXMC 2.0 Monte Carlo code.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24876338
|full-text-url=https://sci-hub.do/10.1093/rpd/ncu174
}}
* {{medline-title
|title=Relationship between identity and attitude toward death in Japanese senior citizens.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24705756
|full-text-url=https://sci-hub.do/10.2152/jmi.61.103
}}
==DBH==
 
* {{medline-title
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711
}}
* {{medline-title
|title=Age-related changes in immunoreactivity for dopamine β-hydroxylase in carotid body glomus cells in spontaneously hypertensive rats.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473232
|full-text-url=https://sci-hub.do/10.1016/j.autneu.2017.04.005
}}
* {{medline-title
|title=Healthy aging increases the cognitive effects of two genes that influence extracellular dopamine.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24956005
|full-text-url=https://sci-hub.do/10.1037/a0036109
}}
==DDC==
 
* {{medline-title
|title=N-Acetyl Cysteine Attenuates the Sarcopenia and Muscle Apoptosis Induced by Chronic Liver Disease.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31530262
|full-text-url=https://sci-hub.do/10.2174/1566524019666190917124636
}}
* {{medline-title
|title=Aging-Related Expression of Twinfilin-1 Regulates Cholangiocyte Biological Response to Injury.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30561764
|full-text-url=https://sci-hub.do/10.1002/hep.30466
}}
* {{medline-title
|title=Life History of Parthenolecanium spp. (Hemiptera: Coccidae) in Urban Landscapes of the Southeastern United States.
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854655
|full-text-url=https://sci-hub.do/10.1093/jee/tox170
}}
==DDO==
 
* {{medline-title
|title=New insights on the influence of free d-aspartate metabolism in the mammalian brain during prenatal and postnatal life.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32561430
|full-text-url=https://sci-hub.do/10.1016/j.bbapap.2020.140471
}}
* {{medline-title
|title=Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822420
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2019.02.014
}}
* {{medline-title
|title=Secreted d-aspartate oxidase functions in C. elegans reproduction and development.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30387556
|full-text-url=https://sci-hub.do/10.1111/febs.14691
}}
==DDX58==
 
* {{medline-title
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|date=14.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
}}
* {{medline-title
|title=Age-associated mRNA expression changes in bovine endometrial cells in vitro.
|date=14.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28806906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556672
}}
* {{medline-title
|title=Progression of pathology in [[PINK1]]-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.
|date=02.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28768533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541666
}}
==DGAT1==
 
* {{medline-title
|title=Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPα-p300/[[DGAT1]] pathway.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771394
}}
* {{medline-title
|title=Genome-wide association study for lactation persistency, female fertility, longevity, and lifetime profit index traits in Holstein dairy cattle.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889128
|full-text-url=https://sci-hub.do/10.3168/jds.2016-11770
}}
* {{medline-title
|title=Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 ([[DGAT1]]) reproduces the abnormalities in lipids found in severe heart failure.
|date=24.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25157099
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207999
}}
==DISC1==
 
* {{medline-title
|title=Age-Related Changes in Topological Degradation of White Matter Networks and Gene Expression in Chronic Schizophrenia.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28946750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695754
}}
* {{medline-title
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
}}
* {{medline-title
|title=PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence.
|date=29.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24706880
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035976
}}
==DKC1==
 
* {{medline-title
|title=Successful liver transplantation in short telomere syndromes without bone marrow failure due to [[DKC1]] mutation.
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32166868
|full-text-url=https://sci-hub.do/10.1111/petr.13695
}}
* {{medline-title
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
}}
* {{medline-title
|title=Cinnamaldehyde and eugenol change the expression folds of [[AKT1]] and [[DKC1]] genes and decrease the telomere length of human adipose-derived stem cells (hASCs): An experimental and in silico study.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28392905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378970
}}
==DMP1==
 
* {{medline-title
|title=Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029870
}}
* {{medline-title
|title=[i]Dmp1[/i] Null Mice Develop a Unique Osteoarthritis-like Phenotype.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27766035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069442
}}
* {{medline-title
|title=Decline in calcitonin receptor expression in osteocytes with age.
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24516262
|full-text-url=https://sci-hub.do/10.1530/JOE-13-0524
}}
==DPT==
 
* {{medline-title
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0
}}
* {{medline-title
|title=Effects of an integrated geriatric group balance class within an entry-level Doctorate of Physical Therapy program on students' perceptions of geriatrics and geriatric education in the United States.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27776400
|full-text-url=https://sci-hub.do/10.3352/jeehp.2016.13.35
}}
* {{medline-title
|title=Auditory Temporal Processing Deficits in Chronic Stroke: A Comparison of Brain Damage Lateralization Effect.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27021038
|full-text-url=https://sci-hub.do/10.1016/j.jstrokecerebrovasdis.2016.02.030
}}
==DRD3==
 
* {{medline-title
|title=Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30439596
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.10.012
}}
* {{medline-title
|title=Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29637543
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105503
}}
* {{medline-title
|title=Dopamine Receptor Genes Modulate Associative Memory in Old Age.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27647283
|full-text-url=https://sci-hub.do/10.1162/jocn_a_01048
}}
==DST==
 
* {{medline-title
|title=Ancestral germen/soma distinction in microbes: Expanding the disposable soma theory of aging to all unicellular lineages.
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268207
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101064
}}
* {{medline-title
|title=Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386173
|full-text-url=https://sci-hub.do/10.1111/jgs.16089
}}
* {{medline-title
|title=The associations between diet quality, Body Mass Index (BMI) and Health and Activity Limitation Index (HALex) in the Geisinger Rural Aging Study (GRAS).
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24522469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550808
}}
==E2F3==
 
* {{medline-title
|title=Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730547
|full-text-url=https://sci-hub.do/10.1016/j.molimm.2018.04.010
}}
* {{medline-title
|title=miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions.
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27979858
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374304
}}
* {{medline-title
|title=Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution.
|date=09.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25284794
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194175
}}
==EHF==
 
* {{medline-title
|title=Extended high frequency hearing and speech perception implications in adults and children.
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32111404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431381
}}
* {{medline-title
|title=[INFLUENCE OF MILLIMETER-WAVE ELECTROMAGNETIC EMISSION ON NITRIC OXIDE SYNTHESIS DURING VESSEL ENDOTHELIUM AGING IN VITRO].
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26390613
 
}}
* {{medline-title
|title=[Molecular mechanisms of combined extremely radiofrequency and infrared therapy in various age patients with chronic parodontitis].
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25946839
 
}}
==ELF3==
 
* {{medline-title
|title=High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in [i]Arabidopsis[/i].
|date=31.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32732458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398796
}}
* {{medline-title
|title=Mutation of Rice Early Flowering3.1 (Os[[ELF3]].1) delays leaf senescence in rice.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27380315
|full-text-url=https://sci-hub.do/10.1007/s11103-016-0507-2
}}
* {{medline-title
|title=Phytochrome-interacting transcription factors PIF4 and PIF5 induce leaf senescence in Arabidopsis.
|date=14.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25119965
|full-text-url=https://sci-hub.do/10.1038/ncomms5636
}}
==EP300==
 
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
* {{medline-title
|title=Aspirin-another caloric-restriction mimetic.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29929449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103658
}}
* {{medline-title
|title=Aspirin Recapitulates Features of Caloric Restriction.
|date=27.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29490275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848858
}}
==EPOR==
 
* {{medline-title
|title=Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27959434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355685
}}
* {{medline-title
|title=Erythropoietin Does Not Enhance Skeletal Muscle Protein Synthesis Following Exercise in Young and Older Adults.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27458387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937030
}}
* {{medline-title
|title=Oxidative stress induces the decline of brain [[EPO]] expression in aging rats.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27452792
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.07.012
}}
==ETS1==
 
* {{medline-title
|title=The transcription factor [[ETS1]] promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1.
|date=06.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31659122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901313
}}
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
* {{medline-title
|title=ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A.
|date=24.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28184004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377799
}}
==F7==
 
* {{medline-title
|title=The Pattern of Mu Rhythm Modulation During Emotional Destination Memory: Comparison Between Mild Cognitive Impairment Patients and Healthy Controls.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524160
|full-text-url=https://sci-hub.do/10.3233/JAD-190311
}}
* {{medline-title
|title=High levels of incidental physical activity are positively associated with cognition and EEG activity in aging.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29370215
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784952
}}
* {{medline-title
|title=[Clinical and genetic characteristics of long-livers in Moscow region].
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693
 
}}
==F9==
 
* {{medline-title
|title=Hypermaintenance and hypofunction of aged spermatogonia: insight from age-related increase of Plzf expression.
|date=30.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25986924
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599245
}}
* {{medline-title
|title=eHealth literacy and Web 2.0 health information seeking behaviors among baby boomers and older adults.
|date=17.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25783036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381816
}}
* {{medline-title
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490
|full-text-url=https://sci-hub.do/10.1071/RD14472
}}
==FABP3==
 
* {{medline-title
|title=[[FABP3]]-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging.
|date=09.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168829
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653047
}}
* {{medline-title
|title=Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing [[FABP3]].
|date=04.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143524
|full-text-url=https://sci-hub.do/10.1080/15548627.2020.1839286
}}
* {{medline-title
|title=Myokines as biomarkers of frailty and cardiovascular disease risk in females.
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32017952
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110859
}}
==FAH==
 
* {{medline-title
|title=Oxaloacetate decarboxylase [[FAH]]D1 - a new regulator of mitochondrial function and senescence.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055189
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.07.007
}}
* {{medline-title
|title=Depletion of oxaloacetate decarboxylase [[FAH]]D1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286170
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.03.004
}}
* {{medline-title
|title=Associations between toe grip strength and hallux valgus, toe curl ability, and foot arch height in Japanese adults aged 20 to 79 years: a cross-sectional study.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25972928
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430032
}}
==FERMT2==
 
* {{medline-title
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
==FOXP1==
 
* {{medline-title
|title=GATA6 regulates aging of human mesenchymal stem/stromal cells.
|date=30.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33252174
|full-text-url=https://sci-hub.do/10.1002/stem.3297
}}
* {{medline-title
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247
}}
* {{medline-title
|title=Downregulation of [[FOXP1]] correlates with tendon stem/progenitor cells aging.
|date=26.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30170733
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.136
}}
==FUNDC1==
 
* {{medline-title
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence.
|date=15.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833
}}
* {{medline-title
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068
}}
* {{medline-title
|title=In Brief: Mitophagy: mechanisms and role in human disease.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27453450
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071152
}}
==FYN==
 
* {{medline-title
|title=An inhibitor role of Nrf2 in the regulation of myocardial senescence and dysfunction after myocardial infarction.
|date=15.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32781064
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118199
}}
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
* {{medline-title
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
}}
==GALC==
 
* {{medline-title
|title=Analysis of age-related changes in psychosine metabolism in the human brain.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29481565
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826537
}}
* {{medline-title
|title=Age and gender-specific reference intervals for lysosomal enzymes in dried blood spot samples: A study in Indian population.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396248
|full-text-url=https://sci-hub.do/10.1016/j.clinbiochem.2017.04.004
}}
* {{medline-title
|title=Long-term Improvements in Lifespan and Pathology in CNS and PNS After BMT Plus One Intravenous Injection of AAVrh10-[[GALC]] in Twitcher Mice.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26329589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817953
}}
==GATA3==
 
* {{medline-title
|title=An imbalance in the T-helper phenotypes displayed by senescent [[CD4]] [[CD28]]  T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111238
|full-text-url=https://sci-hub.do/10.1177/0961203318793715
}}
* {{medline-title
|title=Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30004288
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262508
}}
* {{medline-title
|title=In Vivo Interplay between p27 , [[GATA3]], [[ATOH1]], and [[POU4F3]] Converts Non-sensory Cells to Hair Cells in Adult Mice.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28402854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423718
}}
==GATA6==
 
* {{medline-title
|title=GATA Regulation and Function During the Ovarian Life Cycle.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544631
|full-text-url=https://sci-hub.do/10.1016/bs.vh.2018.01.014
}}
* {{medline-title
|title=Decline in cellular function of aged mouse c-kit  cardiac progenitor cells.
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28737214
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621489
}}
* {{medline-title
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853
}}
==GCK==
 
* {{medline-title
|title=The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31558549
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868460
}}
* {{medline-title
|title=Developmental changes in hepatic glucose metabolism in a newborn piglet model: A comparative analysis for suckling period and early weaning period.
|date=19.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802463
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.01.114
}}
* {{medline-title
|title=Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24405752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965585
}}
==GHSR==
 
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
* {{medline-title
|title=Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329260
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013013
}}
* {{medline-title
|title=Ghrelin accelerates synapse formation and activity development in cultured cortical networks.
|date=17.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24742241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998954
}}
==GLO1==
 
* {{medline-title
|title=The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29259621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723304
}}
* {{medline-title
|title=Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments.
|date=01.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27555612
|full-text-url=https://sci-hub.do/10.1042/CS20160025
}}
* {{medline-title
|title=Glyoxalase I reduces glycative and oxidative stress and prevents age-related endothelial dysfunction through modulation of endothelial nitric oxide synthase phosphorylation.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24612481
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326886
}}
==GNE==
 
* {{medline-title
|title=Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2  mice.
|date=10.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33300446
|full-text-url=https://sci-hub.do/10.1080/15548627.2020.1850008
}}
* {{medline-title
|title=Effects of altered sialic acid biosynthesis on [i]N[/i]-linked glycan branching and cell surface interactions.
|date=09.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28424265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465488
}}
* {{medline-title
|title=Sialyllactose ameliorates myopathic phenotypes in symptomatic [[GNE]] myopathy model mice.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25062695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172045
}}
==GPT==
 
* {{medline-title
|title=Brain Structural-Behavioral Correlates Underlying Grooved Pegboard Test Performance Across Lifespan.
|date=07.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32631206
|full-text-url=https://sci-hub.do/10.1080/00222895.2020.1787320
}}
* {{medline-title
|title=Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31275139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592113
}}
* {{medline-title
|title=A comparative study of glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase ([[GPT]]) levels in the saliva of diabetic and normal patients.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24849491
|full-text-url=https://sci-hub.do/10.3109/10520295.2014.905705
}}
==GPX2==
 
* {{medline-title
|title=RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells.
|date=10.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020613
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639470
}}
* {{medline-title
|title=Maternal obesity in the rat impairs male offspring aging of the testicular antioxidant defence system.
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28063465
|full-text-url=https://sci-hub.do/10.1071/RD16277
}}
* {{medline-title
|title=[[FOXM1]] regulates proliferation, senescence and oxidative stress in keratinocytes and cancer cells.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27385468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993337
}}
==GRK5==
 
* {{medline-title
|title=Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone.
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31043680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494869
}}
* {{medline-title
|title=[[GRK5]] - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30618771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304357
}}
* {{medline-title
|title=[[GRK5]] dysfunction accelerates tau hyperphosphorylation in [[APP]] (swe) mice through impaired cholinergic activity.
|date=07.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24598771
|full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000142
}}
==GSTP1==
 
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
* {{medline-title
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632
}}
* {{medline-title
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201
}}
==HAS2==
 
* {{medline-title
|title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508
|full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7
}}
* {{medline-title
|title=Microvasculature of the Mouse Cerebral Cortex Exhibits Increased Accumulation and Synthesis of Hyaluronan With Aging.
|date=01.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28482035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075594
}}
* {{medline-title
|title=Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26987798
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383204
}}
==HDAC5==
 
* {{medline-title
|title=Emerging roles for histone deacetylases in age-related muscle atrophy.
|date=27.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28035339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166515
}}
* {{medline-title
|title=AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27259535
|full-text-url=https://sci-hub.do/10.1007/s10522-016-9655-7
}}
* {{medline-title
|title=AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27010499
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2016.03.009
}}
==HES1==
 
* {{medline-title
|title=A Single-Cell Transcriptomic Atlas of Human Skin Aging.
|date=23.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33238152
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2020.11.002
}}
* {{medline-title
|title=Hypothesis: cell signalling influences age-related risk of colorectal cancer.
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25388238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288351
}}
* {{medline-title
|title=A transcriptional roadmap to the senescence and differentiation of human oral keratinocytes.
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24398559
|full-text-url=https://sci-hub.do/10.1093/gerona/glt212
}}
==HLA-A==
 
* {{medline-title
|title=Reduced expression of the lncRNA NRON is a potential hallmark of the CMV-amplified CD8  T cell accumulations commonly seen in older humans.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415066
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.004
}}
* {{medline-title
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
}}
* {{medline-title
|title=Telomere Length as an Indicator of the Robustness of B- and T-Cell Response to Influenza in Older Adults.
|date=15.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25828247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577042
}}
==HLA-DRB1==
 
* {{medline-title
|title=The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle.
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32942037
|full-text-url=https://sci-hub.do/10.1016/j.autrev.2020.102670
}}
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
* {{medline-title
|title=[Clinical and genetic characteristics of long-livers in Moscow region].
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693
 
}}
==HRAS==
 
* {{medline-title
|title=How do combinations of unhealthy behaviors relate to attitudinal factors and subjective health among the adult population in the Netherlands?
|date=03.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32245376
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126128
}}
* {{medline-title
|title=Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype.
|date=07.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31940439
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032038
}}
* {{medline-title
|title="Back to the future": Influence of beliefs regarding the future on TTO answers.
|date=12.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26753687
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709901
}}
==HSF2==
 
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
* {{medline-title
|title=Nutrition and water temperature regulate the expression of heat-shock proteins in golden pompano larvae (Trachinotus ovata, Limmaeus 1758).
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30397841
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0578-x
}}
* {{medline-title
|title=Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins.
|date=15.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27038700
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.015
}}
==HSPA1A==
 
* {{medline-title
|title=Vitamin D3 treatment regulates apoptosis, antioxidant defense system, and DNA integrity in the epididymal sperm of an aged rat model.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566824
|full-text-url=https://sci-hub.do/10.1002/mrd.23280
}}
* {{medline-title
|title=The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells.
|date=01.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269563
|full-text-url=https://sci-hub.do/10.1556/2060.105.2018.3.20
}}
* {{medline-title
|title=The Brewed Rice Vinegar Kurozu Increases [[HSPA1A]] Expression and Ameliorates Cognitive Dysfunction in Aged P8 Mice.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26943920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778952
}}
==IDH1==
 
* {{medline-title
|title=GBM-associated mutations and altered protein expression are more common in young patients.
|date=25.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491
}}
* {{medline-title
|title=[[IDH1]] Associated with Neuronal Apoptosis in Adult Rats Brain Following Intracerebral Hemorrhage.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27568302
|full-text-url=https://sci-hub.do/10.1007/s10571-016-0421-9
}}
* {{medline-title
|title=2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling.
|date=01.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26190651
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663076
}}
==IFI16==
 
* {{medline-title
|title=Transcriptomic analysis of purified human cortical microglia reveals age-associated changes.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671693
|full-text-url=https://sci-hub.do/10.1038/nn.4597
}}
* {{medline-title
|title=[[IFI16]], an amplifier of DNA-damage response: Role in cellular senescence and aging-associated inflammatory diseases.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27063514
|full-text-url=https://sci-hub.do/10.1016/j.arr.2016.04.002
}}
* {{medline-title
|title=Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25963977
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450138
}}
==IGF2R==
 
* {{medline-title
|title=Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks.
|date=05-06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29554514
|full-text-url=https://sci-hub.do/10.1016/j.archger.2018.03.004
}}
* {{medline-title
|title=A serum miRNA profile of human longevity: findings from the Baltimore Longitudinal Study of Aging (BLSA).
|date=07.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27824314
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191881
}}
* {{medline-title
|title=Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts.
|date=28.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27167200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129910
}}
==IL15==
 
* {{medline-title
|title=Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of [[IL15]].
|date=27.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32221610
|full-text-url=https://sci-hub.do/10.1093/ageing/afaa035
}}
* {{medline-title
|title=From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration.
|date=22.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28185567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133493
}}
* {{medline-title
|title=Human monocytes have increased IFN-γ-mediated IL-15 production with age alongside altered IFN-γ receptor signaling.
|date=05-06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24657713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018768
}}
==IL1A==
 
* {{medline-title
|title=IL1B triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via CCL2.
|date=25.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099841
|full-text-url=https://sci-hub.do/10.1111/aji.13365
}}
* {{medline-title
|title=Age-associated mRNA expression changes in bovine endometrial cells in vitro.
|date=14.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28806906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556672
}}
* {{medline-title
|title=Age-dependent changes in inflammation and extracellular matrix in bovine oviduct epithelial cells during the post-ovulatory phase.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27580129
|full-text-url=https://sci-hub.do/10.1002/mrd.22693
}}
==INPP5D==
 
* {{medline-title
|title=Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28269768
|full-text-url=https://sci-hub.do/10.3233/JAD-160774
}}
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
==IRF7==
 
* {{medline-title
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|date=14.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
}}
* {{medline-title
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
}}
* {{medline-title
|title=Age-related changes in murine myometrial transcript profile are mediated by exposure to the female sex hormones.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26490259
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717263
}}
==KCNMB2==
 
* {{medline-title
|title=CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of [[GRN]]/P[[GRN]].
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28189700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389672
}}
* {{medline-title
|title=Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: [[GRN]], [[TMEM106B]], [[ABCC9]], and [[KCNMB2]].
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28131462
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385271
}}
* {{medline-title
|title=Hippocampal Sclerosis of Aging, a Common Alzheimer's Disease 'Mimic': Risk Genotypes are Associated with Brain Atrophy Outside the Temporal Lobe.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27003218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978172
}}
==KIN==
 
* {{medline-title
|title=The noncanonical small heat shock protein HSP-17 from [i]Caenorhabditis elegans[/i] is a selective protein aggregase.
|date=06.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32001616
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062175
}}
* {{medline-title
|title=[[KIN]]-4/MAST kinase promotes [[PTEN]]-mediated longevity of Caenorhabditis elegans via binding through a PDZ domain.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30773781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516182
}}
* {{medline-title
|title=Adenine type and diphenyl urea derived cytokinins improve the postharvest performance of [i]Iris germanica[/i] L. cut scapes.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30425429
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214446
}}
==KIT==
 
* {{medline-title
|title=Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-[[KIT]].
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223330
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221484
}}
* {{medline-title
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
}}
* {{medline-title
|title=Comparison of Changes in the Interstitial Cells of Cajal and Neuronal Nitric Oxide Synthase-positive Neuronal Cells With Aging Between the Ascending and Descending Colon of F344 Rats.
|date=30.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28774159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628993
}}
==LAT2==
 
* {{medline-title
|title=Blood glucose, amino acid profiles and nutrient transporter gene expressions in the small intestine of low and normal birthweight piglets during the early suckling period.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971346
|full-text-url=https://sci-hub.do/10.1016/j.tvjl.2019.02.006
}}
* {{medline-title
|title=Skeletal muscle: from birth to old age, routes to mechanical and metabolic failure.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29099099
|full-text-url=https://sci-hub.do/10.24875/GMM.17000008
}}
* {{medline-title
|title=Dihydrotestosterone treatment rescues the decline in protein synthesis as a result of sarcopenia in isolated mouse skeletal muscle fibres.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27239418
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863930
}}
==LCN2==
 
* {{medline-title
|title=Anthropometric and glucometabolic changes in an aged mouse model of lipocalin-2 overexpression.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082752
|full-text-url=https://sci-hub.do/10.1038/s41366-018-0171-5
}}
* {{medline-title
|title=Expression patterns and changes of the [[LCN2]] gene in the testes of induced cryptorchidism and busulfan-treated mice.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28771045
|full-text-url=https://sci-hub.do/10.1080/19396368.2017.1355416
}}
* {{medline-title
|title=[[TCF7L1]] promotes skin tumorigenesis independently of β-catenin through induction of [[LCN2]].
|date=03.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28467300
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438253
}}
==LCT==
 
* {{medline-title
|title=Functional MRI of Letter Cancellation Task Performance in Older Adults.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31057377
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477506
}}
* {{medline-title
|title=Milk Intake at Midlife and Cognitive Decline over 20 Years. The Atherosclerosis Risk in Communities (ARIC) Study.
|date=17.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039795
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691750
}}
* {{medline-title
|title=Frailty phenotype and the role of levodopa challenge test in geriatric inpatients with mild parkinsonian signs.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28612154
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9716-6
}}
==LGR5==
 
* {{medline-title
|title=Thyroid hormone activates Wnt/β-catenin signaling involved in adult epithelial development during intestinal remodeling in Xenopus laevis.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27068920
|full-text-url=https://sci-hub.do/10.1007/s00441-016-2396-8
}}
* {{medline-title
|title=An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth.
|date=01.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834110
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.3010567
}}
* {{medline-title
|title=Cancer stem cells in Helicobacter pylori infection and aging: Implications for gastric carcinogenesis.
|date=15.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25133037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133534
}}
==LOXL2==
 
* {{medline-title
|title=Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice.
|date=27.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31569601
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801581
}}
* {{medline-title
|title=Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening.
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002285
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692735
}}
* {{medline-title
|title=Blood Vessel Basement Membrane Alterations in Human Retinal Microaneurysms During Aging.
|date=01.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28196225
|full-text-url=https://sci-hub.do/10.1167/iovs.16-19998
}}
==LRP6==
 
* {{medline-title
|title=Low-density lipoprotein receptor-related protein 6-mediated signaling pathways and associated cardiovascular diseases: diagnostic and therapeutic opportunities.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32076828
|full-text-url=https://sci-hub.do/10.1007/s00439-020-02124-8
}}
* {{medline-title
|title=Wnt signaling in age-related macular degeneration: human macular tissue and mouse model.
|date=17.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26476672
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609061
}}
* {{medline-title
|title=[[WNT1]]-induced Secreted Protein-1 (WI[[SP1]]), a Novel Regulator of Bone Turnover and Wnt Signaling.
|date=29.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25864198
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447973
}}
==LSR==
 
* {{medline-title
|title=Age-related changes in regiospecific expression of Lipolysis Stimulated Receptor ([[LSR]]) in mice brain.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31233547
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590887
}}
* {{medline-title
|title=Discriminating Alzheimer's disease progression using a new hippocampal marker from T1-weighted MRI: The local surface roughness.
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865478
}}
* {{medline-title
|title=Wave intensity analysis in mice: age-related changes in WIA peaks and correlation with cardiac indexes.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27812747
|full-text-url=https://sci-hub.do/10.1007/s00380-016-0914-y
}}
==MAF==
 
* {{medline-title
|title=Biocatalytic Degradation Efficiency of Postconsumer Polyethylene Terephthalate Packaging Determined by Their Polymer Microstructures.
|date=17.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31380212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662049
}}
* {{medline-title
|title=Binocular and Accommodative Characteristics in a Normal Population.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28095087
|full-text-url=https://sci-hub.do/10.1080/09273972.2016.1276937
}}
* {{medline-title
|title=Association of Klotho and interleukin 6 gene polymorphisms with aging in Han Chinese population.
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25470806
|full-text-url=https://sci-hub.do/10.1007/s12603-014-0470-z
}}
==MAF1==
 
* {{medline-title
|title=Beyond regulation of pol III: Role of [[MAF1]] in growth, metabolism, aging and cancer.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407795
|full-text-url=https://sci-hub.do/10.1016/j.bbagrm.2018.01.019
}}
* {{medline-title
|title=Loss of the RNA polymerase III repressor [[MAF1]] confers obesity resistance.
|date=01.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25934505
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421982
}}
* {{medline-title
|title=Distinct regulation of Maf1 for lifespan extension by Protein kinase A and Sch9.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25720796
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359695
}}
==MAP1B==
 
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
* {{medline-title
|title=[[NOS1]] and [[SNAP25]] polymorphisms are associated with Attention-Deficit/Hyperactivity Disorder symptoms in adults but not in children.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26821215
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2016.01.010
}}
* {{medline-title
|title=Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.
|date=21.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24849348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028492
}}
==MAP3K3==
 
* {{medline-title
|title=miR-188 promotes senescence of lineage-negative bone marrow cells by targeting [[MAP3K3]] expression.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28640956
|full-text-url=https://sci-hub.do/10.1002/1873-3468.12720
}}
* {{medline-title
|title=Functions of miR-9 and miR-9* during Aging in SAMP8 Mice and Their Possible Mechanisms.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26149132
|full-text-url=https://sci-hub.do/10.3881/j.issn.1000-503X.2015.03.001
}}
* {{medline-title
|title=Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26029164
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432801
}}
==MAPK14==
 
* {{medline-title
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
}}
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
* {{medline-title
|title=Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts.
|date=11-12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26794818
|full-text-url=https://sci-hub.do/10.7417/T.2015.1902
}}
==MAPK3==
 
* {{medline-title
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
}}
* {{medline-title
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
}}
* {{medline-title
|title=Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging.
|date=01.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28515230
|full-text-url=https://sci-hub.do/10.1242/jcs.197327
}}
==MAX==
 
* {{medline-title
|title=Validation of the MedUseQ: A Self-Administered Screener for Older Adults to Assess Medication Use Problems.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656678
|full-text-url=https://sci-hub.do/10.1177/0897190018766789
}}
* {{medline-title
|title=Midlife plasma vitamin D concentrations and performance in different cognitive domains assessed 13 years later.
|date=28.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25864611
|full-text-url=https://sci-hub.do/10.1017/S0007114515001051
}}
* {{medline-title
|title=Effect of long-term care use on Medicare and Medicaid expenditures for dual eligible and non-dual eligible elderly beneficiaries.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24753971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983730
}}
==MCAT==
 
* {{medline-title
|title=Small molecules as therapeutic drugs for Alzheimer's disease.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30877034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510253
}}
* {{medline-title
|title=Overexpression of catalase in mice reduces age-related oxidative stress and maintains sperm production.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27575890
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.08.012
}}
* {{medline-title
|title=Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.
|date=25.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26797130
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807251
}}
==MCM7==
 
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
* {{medline-title
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|date=08.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
}}
* {{medline-title
|title=Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26253138
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577010
}}
==MEF2A==
 
* {{medline-title
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|date=10.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
}}
* {{medline-title
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
}}
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
==MGA==
 
* {{medline-title
|title=Fatigue at baseline is associated with geriatric impairments and represents an adverse prognostic factor in older patients with a hematological malignancy.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054708
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182757
}}
* {{medline-title
|title=Geriatric assessment in oncology: Moving the concept forward. The 20 years of experience of the Centre Léon Bérard geriatric oncology program.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29866469
|full-text-url=https://sci-hub.do/10.1016/j.jgo.2018.05.008
}}
* {{medline-title
|title=Degree of Peripheral Thyroxin Deiodination, Frailty, and Long-Term Survival in Hospitalized Older Patients.
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546287
|full-text-url=https://sci-hub.do/10.1210/jc.2017-02149
}}
==MGP==
 
* {{medline-title
|title=Circulating Vitamin K Is Inversely Associated with Incident Cardiovascular Disease Risk among Those Treated for Hypertension in the Health, Aging, and Body Composition Study (Health ABC).
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404216
}}
* {{medline-title
|title=Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma.
|date=21.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28058013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175245
}}
* {{medline-title
|title=[Bone metabolism and cardiovascular function update. Cross link of hypertension, bone loss and vascular calcification - common back grounds in renin angiotensin system with anti-aging aspect -].
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24976056
|full-text-url=https://sci-hub.do/CliCa140710211030
}}
==MGRN1==
 
* {{medline-title
|title=Chronic and age-dependent effects of the spongiform neurodegeneration-associated [[MGRN1]] E3 ubiquitin ligase on mitochondrial homeostasis.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089807
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639055
}}
* {{medline-title
|title=Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival.
|date=04.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28475871
|full-text-url=https://sci-hub.do/10.1016/j.molcel.2017.04.005
}}
* {{medline-title
|title=Mahogunin Ring Finger-1 ([[MGRN1]]), a Multifaceted Ubiquitin Ligase: Recent Unraveling of Neurobiological Mechanisms.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26255182
|full-text-url=https://sci-hub.do/10.1007/s12035-015-9379-8
}}
==MLKL==
 
* {{medline-title
|title=Remifentanil preconditioning protects against hypoxia-induced senescence and necroptosis in human cardiac myocytes [i]in vitro[/i].
|date=25.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32584786
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425462
}}
* {{medline-title
|title=Necroptosis increases with age and is reduced by dietary restriction.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696779
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052392
}}
* {{medline-title
|title=[[RIPK1]]-[[RIPK3]]-[[MLKL]]-dependent necrosis promotes the aging of mouse male reproductive system.
|date=15.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807105
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557593
}}
==MMP12==
 
* {{medline-title
|title=Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for [[MMP12]] through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice.
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814604
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1601696
}}
* {{medline-title
|title=Differential Matrix Metalloprotease (MMP) Expression Profiles Found in Aged Gingiva.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938517
}}
* {{medline-title
|title=Matrix metalloproteinase-12 is an essential mediator of acute and chronic arterial stiffening.
|date=26.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26608672
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4660439
}}
==MMP7==
 
* {{medline-title
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
}}
* {{medline-title
|title=High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28129359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271178
}}
* {{medline-title
|title=Metzincins and related genes in experimental renal ageing: towards a unifying fibrosis classifier across species.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24569495
|full-text-url=https://sci-hub.do/10.1093/ndt/gfu027
}}
==MS4A4E==
 
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
* {{medline-title
|title=Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28269768
|full-text-url=https://sci-hub.do/10.3233/JAD-160774
}}
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
==MST1==
 
* {{medline-title
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
 
}}
* {{medline-title
|title=High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28129359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5271178
}}
* {{medline-title
|title=Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases [[MST1]] and MST2.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27940445
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210079
}}
==MT1A==
 
* {{medline-title
|title=Pharmacological advantages of melatonin in immunosenescence by improving activity of T lymphocytes.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27533940
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946322
}}
* {{medline-title
|title=A novel strain of Lactobacillus mucosae isolated from a Gaotian villager improves in vitro and in vivo antioxidant as well as biological properties in D-galactose-induced aging mice.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26709186
|full-text-url=https://sci-hub.do/10.3168/jds.2015-10265
}}
* {{medline-title
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201
}}
==MTNR1B==
 
* {{medline-title
|title=Analysis of [[MTNR1B]] gene polymorphisms in relationship with [[IRS2]] gene variants, epicardial fat thickness, glucose homeostasis and cognitive performance in the elderly.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708046
|full-text-url=https://sci-hub.do/10.1080/07420528.2017.1340894
}}
* {{medline-title
|title=Melatonin and the pathologies of weakened or dysregulated circadian oscillators.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27763686
|full-text-url=https://sci-hub.do/10.1111/jpi.12377
}}
* {{medline-title
|title=Association of osteoporosis with genetic variants of circadian genes in Chinese geriatrics.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26564225
|full-text-url=https://sci-hub.do/10.1007/s00198-015-3391-8
}}
==MUC5AC==
 
* {{medline-title
|title=InflammAging at Ocular Surface: Clinical and Biomolecular Analyses in Healthy Volunteers.
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31022299
|full-text-url=https://sci-hub.do/10.1167/iovs.18-25822
}}
* {{medline-title
|title=Expression of polycomb protein BMI-1 maintains the plasticity of basal bronchial epithelial cells.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27558999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002903
}}
* {{medline-title
|title=Immunohistochemical Expressions of MUC2, [[MUC5AC]], and MUC6 in Normal, Helicobacter pylori Infected and Metaplastic Gastric Mucosa of Children and Adolescents.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25704078
|full-text-url=https://sci-hub.do/10.1111/hel.12198
}}
==MUS81==
 
* {{medline-title
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
}}
* {{medline-title
|title=[[MUS81]] is associated with cell proliferation and cisplatin sensitivity in serous ovarian cancer.
|date=05.08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27255997
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.05.152
}}
* {{medline-title
|title=Acute [[MUS81]] depletion leads to replication fork slowing and a constitutive DNA damage response.
|date=10.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26415217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741954
}}
==NDRG1==
 
* {{medline-title
|title=Cx43 phosphorylation-mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein [[NDRG1]].
|date=02.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682735
}}
* {{medline-title
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
* {{medline-title
|title=mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and [[PAPPA]]-KO mice.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27618784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242303
}}
==NDRG2==
 
* {{medline-title
|title=[[NDRG2]] Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain.
|date=04.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31947996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982267
}}
* {{medline-title
|title=The pathological roles of [[NDRG2]] in Alzheimer's disease, a study using animal models and APPwt-overexpressed cells.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28670853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492714
}}
* {{medline-title
|title=Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27442752
|full-text-url=https://sci-hub.do/10.1111/nan.12338
}}
==NDUFB8==
 
* {{medline-title
|title=Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats.
|date=23.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29882895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032417
}}
* {{medline-title
|title=Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29802507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060193
}}
* {{medline-title
|title=Resveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26873850
|full-text-url=https://sci-hub.do/10.1007/s12035-016-9770-0
}}
==NFKB1==
 
* {{medline-title
|title=[[NFKB1]] gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32002656
|full-text-url=https://sci-hub.do/10.1007/s00277-020-03935-5
}}
* {{medline-title
|title=The Inflammatory Transcription Factors NFκB, [[STAT1]] and [[STAT3]] Drive Age-Associated Transcriptional Changes in the Human Kidney.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26678048
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682820
}}
* {{medline-title
|title=[[NFKB1]]: a suppressor of inflammation, ageing and cancer.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26663363
|full-text-url=https://sci-hub.do/10.1111/febs.13627
}}
==NOA1==
 
* {{medline-title
|title=The dependence of leaf senescence on the balance between 1-aminocyclopropane-1-carboxylate acid synthase 1 (ACS1)-catalysed ACC generation and nitric oxide-associated 1 (NOS1)-dependent NO accumulation in Arabidopsis.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30734982
|full-text-url=https://sci-hub.do/10.1111/plb.12970
}}
* {{medline-title
|title=Low concentrations of salicylic acid delay methyl jasmonate-induced leaf senescence by up-regulating nitric oxide synthase activity.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27440938
|full-text-url=https://sci-hub.do/10.1093/jxb/erw280
}}
* {{medline-title
|title=Two homologous protein S-acyltransferases, PAT13 and PAT14, cooperatively regulate leaf senescence in Arabidopsis.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26160582
|full-text-url=https://sci-hub.do/10.1093/jxb/erv347
}}
==NOG==
 
* {{medline-title
|title=The p53 Pathway Controls [[SOX2]]-Mediated Reprogramming in the Adult Mouse Spinal Cord.
|date=11.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27732862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094368
}}
* {{medline-title
|title=Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26161905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498777
}}
* {{medline-title
|title=Nucleolar GTPase [[NOG]]-1 regulates development, fat storage, and longevity through insulin/IGF signaling in C. elegans.
|date=01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24552710
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907010
}}
==NOTCH3==
 
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
* {{medline-title
|title=Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny.
|date=13.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26436701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741551
}}
==NOX1==
 
* {{medline-title
|title=Identification of the mechanisms by which age alters the mechanosensitivity of mesenchymal stromal cells on substrates of differing stiffness: Implications for osteogenesis and angiogenesis.
|date=15.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28216301
|full-text-url=https://sci-hub.do/10.1016/j.actbio.2017.02.031
}}
* {{medline-title
|title=Antioxidant Supplementation Modulates Age-Related Placental Bed Morphology and Reproductive Outcome in Mice.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26178715
|full-text-url=https://sci-hub.do/10.1095/biolreprod.114.127746
}}
* {{medline-title
|title=NADPH oxidase [[NOX1]] is involved in activation of protein kinase C and premature senescence in early stage diabetic kidney.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25701431
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2015.02.009
}}
==NPM1==
 
* {{medline-title
|title=Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats.
|date=29.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31784606
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884578
}}
* {{medline-title
|title=Sirtuin 7 in cell proliferation, stress and disease: Rise of the Seventh Sirtuin!
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25435428
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2014.11.026
}}
* {{medline-title
|title=Comparative interactomes of [[SIRT6]] and [[SIRT7]]: Implication of functional links to aging.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24782448
|full-text-url=https://sci-hub.do/10.1002/pmic.201400001
}}
==OCM==
 
* {{medline-title
|title=Survival Outcomes in Octogenarian and Nonagenarian Patients Treated with First-line Androgen Deprivation Therapy for Organ-confined Prostate Cancer.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28753853
|full-text-url=https://sci-hub.do/10.1016/j.euf.2017.01.017
}}
* {{medline-title
|title=Comorbidity and age cannot explain variation in life expectancy associated with treatment of non-metastatic prostate cancer.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27796538
|full-text-url=https://sci-hub.do/10.1007/s00345-016-1963-7
}}
* {{medline-title
|title=Changing Trends in Surgical Management of Prostate Cancer: The End of Overtreatment?
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25736732
|full-text-url=https://sci-hub.do/10.1016/j.eururo.2015.02.020
}}
==OSM==
 
* {{medline-title
|title=Age Differences in Sexual Minority Stress and the Importance of Friendship in Later Life.
|date=04.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143546
|full-text-url=https://sci-hub.do/10.1080/07317115.2020.1836107
}}
* {{medline-title
|title=[[STAT3]]-mediated [[SMAD3]] activation underlies Oncostatin M-induced Senescence.
|date=16.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27892764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324753
}}
* {{medline-title
|title=Caenorhabditis elegans [[OSM]]-11 signaling regulates SKN-1/Nrf during embryonic development and adult longevity and stress response.
|date=01.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25637691
|full-text-url=https://sci-hub.do/10.1016/j.ydbio.2015.01.021
}}
==OTX2==
 
* {{medline-title
|title=Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice.
|date=01.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29337233
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819331
}}
* {{medline-title
|title=Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts.
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635509
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576272
}}
* {{medline-title
|title=Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics.
|date=08.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27267879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897877
}}
==OXR1==
 
* {{medline-title
|title=Oxidation resistance 1 is a novel senolytic target.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29766639
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052462
}}
* {{medline-title
|title=Cloning of cDNA encoding a Bombyx mori homolog of human oxidation resistance 1 ([[OXR1]]) protein from diapause eggs, and analyses of its expression and function.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25010546
|full-text-url=https://sci-hub.do/10.1016/j.jinsphys.2014.06.020
}}
* {{medline-title
|title=Oxidation resistance 1 is essential for protection against oxidative stress and participates in the regulation of aging in Caenorhabditis elegans.
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24865925
|full-text-url=https://sci-hub.do/10.3109/10715762.2014.927063
}}
==PABPN1==
 
* {{medline-title
|title=Dysfunctional transcripts are formed by alternative polyadenylation in OPMD.
|date=26.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650278
}}
* {{medline-title
|title=[[PABPN1]]-Dependent mRNA Processing Induces Muscle Wasting.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27152426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859507
}}
* {{medline-title
|title=A novel feed-forward loop between [[ARIH2]] E3-ligase and [[PABPN1]] regulates aging-associated muscle degeneration.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24486325
|full-text-url=https://sci-hub.do/10.1016/j.ajpath.2013.12.011
}}
==PAPPA==
 
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
* {{medline-title
|title=mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and [[PAPPA]]-KO mice.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27618784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242303
}}
==PER1==
 
* {{medline-title
|title=Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells.
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31773385
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05194-8
}}
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
* {{medline-title
|title=Ectopic expression of Nn[[PER1]], a Nelumbo nucifera 1-cysteine peroxiredoxin antioxidant, enhances seed longevity and stress tolerance in Arabidopsis.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27464651
|full-text-url=https://sci-hub.do/10.1111/tpj.13286
}}
==PF4==
 
* {{medline-title
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
}}
* {{medline-title
|title=Effects of collagen peptides intake on skin ageing and platelet release in chronologically aged mice revealed by cytokine array analysis.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28922541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742730
}}
* {{medline-title
|title=Changes in platelet morphology and function during 24 hours of storage.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25227196
|full-text-url=https://sci-hub.do/10.3233/CH-141876
}}
==PHB==
 
* {{medline-title
|title=Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30674441
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412871
}}
* {{medline-title
|title=Analysis of the effect of the mitochondrial prohibitin complex, a context-dependent modulator of longevity, on the C. elegans metabolome.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26092086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580209
}}
* {{medline-title
|title=Prohibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25265021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180437
}}
==PIK3CG==
 
* {{medline-title
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|date=10.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
}}
* {{medline-title
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
}}
* {{medline-title
|title=Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951662
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112104
}}
==PLD2==
 
* {{medline-title
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
}}
* {{medline-title
|title=Role of phospholipase D in the lifespan of Caenorhabditis elegans.
|date=06.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29622768
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938010
}}
* {{medline-title
|title=Phospholipase D2 downregulation induces cellular senescence through a reactive oxygen species-p53-p21Cip1/WAF1 pathway.
|date=25.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25064843
|full-text-url=https://sci-hub.do/10.1016/j.febslet.2014.07.009
}}
==PLIN2==
 
* {{medline-title
|title=Cardiac overexpression of perilipin 2 induces atrial steatosis, connexin 43 remodeling, and atrial fibrillation in aged mice.
|date=01.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31661297
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957375
}}
* {{medline-title
|title=[[HDAC6]] Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of [[PLIN2]] in Drosophila.
|date=09.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28966044
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2017.09.001
}}
* {{medline-title
|title=Effects of immobilization and aerobic training on proteins related to intramuscular substrate storage and metabolism in young and older men.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26626913
|full-text-url=https://sci-hub.do/10.1007/s00421-015-3302-x
}}
==PLN==
 
* {{medline-title
|title=An analysis of the costs of treating aged patients in a large clinical hospital in Poland under the pressure of recent demographic trends.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399116
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212232
}}
* {{medline-title
|title=Molecular evidence on the protective effect of ellagic acid on phosalone-induced senescence in rat embryonic fibroblast cells.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27965107
|full-text-url=https://sci-hub.do/10.1016/j.fct.2016.12.008
}}
* {{medline-title
|title=Health outcomes and economic consequences of using angiotensin-converting enzyme inhibitors in comparison with angiotensin receptor blockers in the treatment of arterial hypertension in the contemporary Polish setting.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27112942
|full-text-url=https://sci-hub.do/10.5603/KP.a2016.0055
}}
==POSTN==
 
* {{medline-title
|title=A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals [[POSTN]] As a New Element in Proline Metabolic Disorder.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284769
}}
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
* {{medline-title
|title=Age-dependent changes in inflammation and extracellular matrix in bovine oviduct epithelial cells during the post-ovulatory phase.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27580129
|full-text-url=https://sci-hub.do/10.1002/mrd.22693
}}
==POT1==
 
* {{medline-title
|title=MiR-185 targets [[POT1]] to induce telomere dysfunction and cellular senescence.
|date=18.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32687062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425516
}}
* {{medline-title
|title=Seryl tRNA synthetase cooperates with [[POT1]] to regulate telomere length and cellular senescence.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31815007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882858
}}
* {{medline-title
|title=A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region.
|date=03.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26462146
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742130
}}
==PPARG==
 
* {{medline-title
|title=The [[PPARG]] Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity.
|date=04-06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29116943
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938164
}}
* {{medline-title
|title=The [[ADAMTS9]] gene is associated with cognitive aging in the elderly in a Taiwanese population.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28225792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321460
}}
* {{medline-title
|title=[Genotype and allele frequencies of U[[CP]] and PP[[AR]] gene families in residents of besieged Leningrad and in the control group].
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826986
 
}}
==PPARGC1A==
 
* {{medline-title
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
}}
* {{medline-title
|title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417
}}
* {{medline-title
|title=Synergistic effect of high charge and energy particle radiation and chronological age on biomarkers of oxidative stress and tissue degeneration: a ground-based study using the vertebrate laboratory model organism Oryzias latipes.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25375139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222877
}}
==PRDX1==
 
* {{medline-title
|title=Active vitamin D supplementation alleviates initiation and progression of nonalcoholic fatty liver disease by repressing the p53 pathway.
|date=15.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31756344
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.117086
}}
* {{medline-title
|title=[[PRDX1]] and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase.
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29773556
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004070
}}
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
==PRDX3==
 
* {{medline-title
|title=Proteomic analyses reveal that ginsenoside Rg3([i]S[/i]) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32148389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033328
}}
* {{medline-title
|title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training.
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857
}}
* {{medline-title
|title=The impact of preserved Klotho gene expression on antioxidative stress activity in healthy kidney.
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29693450
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00486.2017
}}
==PRDX6==
 
* {{medline-title
|title=Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31417400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684764
}}
* {{medline-title
|title=Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts.
|date=11-12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26794818
|full-text-url=https://sci-hub.do/10.7417/T.2015.1902
}}
* {{medline-title
|title=Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25796034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371547
}}
==PRKG1==
 
* {{medline-title
|title=Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis.
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660387
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.04.007
}}
* {{medline-title
|title=Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle.
|date=29.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671246
|full-text-url=https://sci-hub.do/10.4238/gmr16029091
}}
* {{medline-title
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
==PSEN2==
 
* {{medline-title
|title=Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human [[PSEN2]].
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31978074
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980398
}}
* {{medline-title
|title=Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31862541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462087
}}
* {{medline-title
|title=Characterization of Amyloid-β Deposits in Bovine Brains.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26890772
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927890
}}
==PTK2B==
 
* {{medline-title
|title=Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354244
}}
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
==PTN==
 
* {{medline-title
|title=Connecting Metainflammation and Neuroinflammation Through the [[PTN]]-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31031625
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474308
}}
* {{medline-title
|title=Early Disruption of Extracellular Pleiotrophin Distribution Alters Cerebellar Neuronal Circuit Development and Function.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26399645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012153
}}
* {{medline-title
|title=Mass spectrometric analysis of protein tyrosine nitration in aging and neurodegenerative diseases.
|date=03-04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24889964
|full-text-url=https://sci-hub.do/10.1002/mas.21429
}}
==PTPN11==
 
* {{medline-title
|title=Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array.
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32888012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568434
}}
* {{medline-title
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
}}
* {{medline-title
|title=GBM-associated mutations and altered protein expression are more common in young patients.
|date=25.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491
}}
==RAD52==
 
* {{medline-title
|title=Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae.
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075257
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563841
}}
* {{medline-title
|title=Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human [[RAD52]] gene in a cardiovascular cohort.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024686
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.10.003
}}
* {{medline-title
|title=Functional characterization of [[RAD52]] as a lung cancer susceptibility gene in the 12p13.33 locus.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26013599
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662629
}}
==RAN==
 
* {{medline-title
|title=Rapid automatized naming ([[RAN]]): effects of aging on a predictor of reading skill.
|date=17.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32799742
|full-text-url=https://sci-hub.do/10.1080/13825585.2020.1806987
}}
* {{medline-title
|title=SCA8 [[RAN]] polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F.
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166133
}}
* {{medline-title
|title=Responses to Predictable versus Random Temporally Complex Stimuli from Single Units in Auditory Thalamus: Impact of Aging and Anesthesia.
|date=12.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27733619
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059434
}}
==RCAN1==
 
* {{medline-title
|title=Mitochondrial dysfunction and endoplasmic reticulum stress involved in oocyte aging: an analysis using single-cell RNA-sequencing of mouse oocytes.
|date=08.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31176373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556043
}}
* {{medline-title
|title=[[RCAN1]] overexpression promotes age-dependent mitochondrial dysregulation related to neurodegeneration in Alzheimer's disease.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26497675
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782929
}}
* {{medline-title
|title=Chaperone-mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation.
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25263126
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208273
}}
==RDX==
 
* {{medline-title
|title=Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25796034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371547
}}
* {{medline-title
|title=A peroxiredoxin, P[[RDX]]-2, is required for insulin secretion and insulin/IIS-dependent regulation of stress resistance and longevity.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25808059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531070
}}
* {{medline-title
|title=Toxicity of the conventional energetics TNT and [[RDX]] relative to new insensitive munitions constituents DNAN and NTO in Rana pipiens tadpoles.
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25586961
|full-text-url=https://sci-hub.do/10.1002/etc.2890
}}
==RECQL4==
 
* {{medline-title
|title=Aging in Rothmund-Thomson syndrome and related [[RECQL4]] genetic disorders.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27287744
|full-text-url=https://sci-hub.do/10.1016/j.arr.2016.06.002
}}
* {{medline-title
|title=Bloom's syndrome: Why not premature aging?: A comparison of the [[BLM]] and [[WRN]] helicases.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27238185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124422
}}
* {{medline-title
|title=Senescence induced by [[RECQL4]] dysfunction contributes to Rothmund-Thomson syndrome features in mice.
|date=15.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24832598
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047874
}}
==RGN==
 
* {{medline-title
|title=Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29675370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902356
}}
* {{medline-title
|title=Effect of supplementation of recombinant Regucalcin in extender on cryopreservation of spermatozoa of water buffalo (Bubalus bubalis).
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782859
|full-text-url=https://sci-hub.do/10.1002/mrd.22873
}}
* {{medline-title
|title=Aging-associated changes in oxidative stress, cell proliferation, and apoptosis are prevented in the prostate of transgenic rats overexpressing regucalcin.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26397424
|full-text-url=https://sci-hub.do/10.1016/j.trsl.2015.08.009
}}
==RGR==
 
* {{medline-title
|title=Relative growth rate in phylogenetically related deciduous and evergreen woody species.
|date=07.2001
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28547465
|full-text-url=https://sci-hub.do/10.1007/s004420100645
}}
* {{medline-title
|title=Tolerance to herbivory and the resource availability hypothesis.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28490446
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454241
}}
* {{medline-title
|title=Linking size-dependent growth and mortality with architectural traits across 145 co-occurring tropical tree species.
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24669729
|full-text-url=https://sci-hub.do/10.1890/11-2173.1
}}
==RGS2==
 
* {{medline-title
|title=Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone.
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31043680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494869
}}
* {{medline-title
|title=Regulator of G protein signaling 2 is a key regulator of pancreatic β-cell mass and function.
|date=25.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28542139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520679
}}
* {{medline-title
|title=miR-17 extends mouse lifespan by inhibiting senescence signaling mediated by MKP7.
|date=31.07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25077541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123096
}}
==RNF8==
 
* {{medline-title
|title=Expression of [[RNF8]] on cochlear apoptosis and aging in mice of different ages.
|date=03-Apr,.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915826
 
}}
* {{medline-title
|title=Function of RAD6B and [[RNF8]] in spermatogenesis.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884393
}}
* {{medline-title
|title=HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and [[HBZ]].
|date=16.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27322308
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926181
}}
==RORA==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
* {{medline-title
|title=Effects of circadian clock genes and environmental factors on cognitive aging in old adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421829
}}
* {{medline-title
|title=Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27268410
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986421
}}
==RPL11==
 
* {{medline-title
|title=[[NOL12]] Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
|date=15.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549468
}}
* {{medline-title
|title=Protection against High-Fat-Diet-Induced Obesity in [[MDM2]]  Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure.
|date=24.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28122227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560502
}}
* {{medline-title
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
==RPTOR==
 
* {{medline-title
|title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016
}}
* {{medline-title
|title=MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation.
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25751060
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396470
}}
* {{medline-title
|title=Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366598
}}
==S1PR1==
 
* {{medline-title
|title=Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair.
|date=22.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544390
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607448
}}
* {{medline-title
|title=Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota.
|date=04.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754350
}}
* {{medline-title
|title=Hypothalamic S1P/[[S1PR1]] axis controls energy homeostasis in Middle-Aged Rodents: the reversal effects of physical exercise.
|date=26.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039439
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310661
}}
==SCAP==
 
* {{medline-title
|title=Dementia outcomes after addition of proxy-based assessments for deceased or proxy-dependent participants.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31034676
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742525
}}
* {{medline-title
|title=Increased hepatic INSIG-[[SCAP]]-SREBP expression is associated with cholesterol metabolism disorder in assisted reproductive technology-conceived aged mice.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30562550
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2018.12.003
}}
* {{medline-title
|title=[Individually Safe and Realistic Correction of Antipsychotic Polypharmacy and High-dose Regimens in Japanese Patients with Chronic Schizophrenia: The [[SCAP]] method].
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26524843
 
}}
==SERPINE1==
 
* {{medline-title
|title=Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes.
|date=15.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056555
|full-text-url=https://sci-hub.do/10.1016/j.placenta.2019.12.012
}}
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
}}
* {{medline-title
|title=A null mutation in [i][[SERPINE1]][/i] protects against biological aging in humans.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29152572
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687852
}}
==SHE==
 
* {{medline-title
|title=Strong, healthy, energized: Striving for a healthy weight in an older lesbian population.
|date=05-06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27484950
|full-text-url=https://sci-hub.do/10.1080/08952841.2015.1137436
}}
* {{medline-title
|title=A mechanistic evaluation of the Syrian hamster embryo cell transformation assay (pH 6.7) and molecular events leading to senescence bypass in [[SHE]] cells.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27169376
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877681
}}
* {{medline-title
|title=Short-Term Buffers, but Long-Term Suffers? Differential Effects of Negative Self-Perceptions of Aging Following Serious Health Events.
|date=01.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26443013
|full-text-url=https://sci-hub.do/10.1093/geronb/gbv058
}}
==SKP2==
 
* {{medline-title
|title=Nuclear AMPK regulated [[CARM1]] stabilization impacts autophagy in aged heart.
|date=29.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28315332
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.03.053
}}
* {{medline-title
|title=14-3-3β Depletion Drives a Senescence Program in Glioblastoma Cells Through the ERK/[[SKP2]]/p27 Pathway.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28116547
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0407-8
}}
* {{medline-title
|title=Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26987798
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383204
}}
==SMC3==
 
* {{medline-title
|title=Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667147
|full-text-url=https://sci-hub.do/10.1007/s11655-018-2835-3
}}
* {{medline-title
|title=The effect of DHEA on apoptosis and cohesin levels in oocytes in aged mice.
|date=12.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28717062
|full-text-url=https://sci-hub.do/10.5582/bst.2017.01108
}}
* {{medline-title
|title=Elevated intracellular pH appears in aged oocytes and causes oocyte aneuploidy associated with the loss of cohesion in mice.
|date=16.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27472084
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026820
}}
==SMN1==
 
* {{medline-title
|title=Changing respiratory expectations with the new disease trajectory of nusinersen treated spinal muscular atrophy [SMA] type 1.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414815
|full-text-url=https://sci-hub.do/10.1016/j.prrv.2018.07.002
}}
* {{medline-title
|title=Type 0 Spinal Muscular Atrophy: Further Delineation of Prenatal and Postnatal Features in 16 Patients.
|date=29.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27911332
|full-text-url=https://sci-hub.do/10.3233/JND-160177
}}
* {{medline-title
|title=Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy.
|date=27.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27621445
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047168
}}
==SNAI1==
 
* {{medline-title
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
}}
* {{medline-title
|title=O-GlcNAcylation is required for mutant [[KRAS]]-induced lung tumorigenesis.
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205381
}}
* {{medline-title
|title=Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16  inactivation.
|date=26.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482580
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828408
}}
==SOST==
 
* {{medline-title
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448
}}
* {{medline-title
|title=Bone adaptation in response to treadmill exercise in young and adult mice.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29379848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787623
}}
* {{medline-title
|title=[[WNT1]]-induced Secreted Protein-1 (WI[[SP1]]), a Novel Regulator of Bone Turnover and Wnt Signaling.
|date=29.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25864198
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447973
}}
==SOX4==
 
* {{medline-title
|title=Age-induced accumulation of methylmalonic acid promotes tumour progression.
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32814897
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2630-0
}}
* {{medline-title
|title=P4 medicine and osteoporosis: a systematic review.
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27873024
|full-text-url=https://sci-hub.do/10.1007/s00508-016-1125-3
}}
* {{medline-title
|title=Upregulation of [[SOX4]] antagonizes cellular senescence in esophageal squamous cell carcinoma.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27446439
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950821
}}
==SPRTN==
 
* {{medline-title
|title=Tandem Deubiquitination and Acetylation of [[SPRTN]] Promotes DNA-Protein Crosslink Repair and Protects against Aging.
|date=03.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32649882
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484104
}}
* {{medline-title
|title=Metalloprotease [[SPRTN]]/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.
|date=17.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27871366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128727
}}
* {{medline-title
|title=[[SPRTN]] is a mammalian DNA-binding metalloprotease that resolves DNA-protein crosslinks.
|date=17.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27852435
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127644
}}
==SRI==
 
* {{medline-title
|title=The Role of Aging, Drug Dependence, and Hepatitis C Comorbidity in Alcoholism Cortical Compromise.
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29541774
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875381
}}
* {{medline-title
|title=Fluoxetine induces input-specific hippocampal dendritic spine remodeling along the septotemporal axis in adulthood and middle age.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25850664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596739
}}
* {{medline-title
|title=Role of the serotonin transporter gene locus in the response to S[[SRI]] treatment of major depressive disorder in late life.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25827644
|full-text-url=https://sci-hub.do/10.1177/0269881115578159
}}
==STAC==
 
* {{medline-title
|title=Obesity and Aging: Consequences for Cognition, Brain Structure, and Brain Function.
|date=07-08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26107577
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648343
}}
* {{medline-title
|title=Genetic risk for Alzheimer's disease alters the five-year trajectory of semantic memory activation in cognitively intact elders.
|date=01.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25687593
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387085
}}
* {{medline-title
|title=How does it [[STAC]] up? Revisiting the scaffolding theory of aging and cognition.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25143069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150993
}}
==STAT6==
 
* {{medline-title
|title=[[IL4]]/[[STAT6]] Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain.
|date=18.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27760324
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2016.09.075
}}
* {{medline-title
|title=[[STAT6]] inhibitory peptide given during RSV infection of neonatal mice reduces exacerbated airway responses upon adult reinfection.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27566834
|full-text-url=https://sci-hub.do/10.1189/jlb.4A0215-062RR
}}
* {{medline-title
|title=The role of STAT transcription factors in apoptosis regulation of hypothalamic neurons in aging in HER-2/neu transgenic mice and wild-type FVB/N mice.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27417725
|full-text-url=https://sci-hub.do/10.1134/S1607672916030169
}}
==STIM1==
 
* {{medline-title
|title=Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis.
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31833196
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996945
}}
* {{medline-title
|title=Ca  entry via [[TRPC1]] is essential for cellular differentiation and modulates secretion via the SNARE complex.
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397
}}
* {{medline-title
|title=Calcium Dynamics of Ex Vivo Long-Term Cultured CD8  T Cells Are Regulated by Changes in Redox Metabolism.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27526200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985122
}}
==SYK==
 
* {{medline-title
|title=miR-25-3p promotes endothelial cell angiogenesis in aging mice via TULA-2/[[SYK]]/VEGFR-2 downregulation.
|date=17.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33201836
|full-text-url=https://sci-hub.do/10.18632/aging.103834
}}
* {{medline-title
|title=Identification of [[SYK]] inhibitor, R406 as a novel senolytic agent.
|date=07.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32379705
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244031
}}
* {{medline-title
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
==SYP==
 
* {{medline-title
|title=The neuropeptide-12 improves recognition memory and neuronal plasticity of the limbic system in old rats.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29740871
|full-text-url=https://sci-hub.do/10.1002/syn.22036
}}
* {{medline-title
|title=Aging alters the molecular dynamics of synapses in a sexually dimorphic pattern in zebrafish (Danio rerio).
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28314159
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.02.007
}}
* {{medline-title
|title=The reciprocal links between synaptophysin serum levels and the prevalence of metabolic syndrome according to selected low-grade inflammation indices and age-related androgen serum level changes in men.
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26891429
 
}}
==TAS2R38==
 
* {{medline-title
|title=[[TAS2R38]] bitter taste receptor and attainment of exceptional longevity.
|date=02.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889489
}}
* {{medline-title
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects.
|date=18.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
}}
* {{medline-title
|title=Age-related differences in bitter taste and efficacy of bitter blockers.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25050705
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106902
}}
==TES==
 
* {{medline-title
|title=The Effects of Electrical Stimulation Pulse Duration on Lingual Palatal Pressure Measures During Swallowing in Healthy Older Adults.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820657
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456514
}}
* {{medline-title
|title=Comparison of different extenders on the recovery and longevity of epididymal sperm from Spix's yellow-toothed cavies (Galea spixii Wagler, 1831).
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28245889
|full-text-url=https://sci-hub.do/10.1017/S0967199417000016
}}
* {{medline-title
|title=Aging Affects Identification of Vocal Emotions in Semantically Neutral Sentences.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25810032
|full-text-url=https://sci-hub.do/10.1044/2015_JSLHR-H-14-0256
}}
==TET3==
 
* {{medline-title
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
}}
* {{medline-title
|title=Dynamic changes in DNA demethylation in the tree shrew ([i]Tupaia belangeri chinensis[/i]) brain during postnatal development and aging.
|date=18.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28409505
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396032
}}
* {{medline-title
|title=5-azacytidine improves the osteogenic differentiation potential of aged human adipose-derived mesenchymal stem cells by DNA demethylation.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24603866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946260
}}
==TGFB1==
 
* {{medline-title
|title=Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28812215
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665708
}}
* {{medline-title
|title=Seminal plasma transforming growth factor-β, activin A and follistatin fluctuate within men over time.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27609985
|full-text-url=https://sci-hub.do/10.1093/humrep/dew185
}}
* {{medline-title
|title=No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709
}}
==THRB==
 
* {{medline-title
|title=Age-associated increase of thyroid hormone receptor β gene promoter methylation coexists with decreased gene expression.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733698
|full-text-url=https://sci-hub.do/10.1080/07435800.2018.1469648
}}
* {{medline-title
|title=Genome-wide association study for lactation persistency, female fertility, longevity, and lifetime profit index traits in Holstein dairy cattle.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889128
|full-text-url=https://sci-hub.do/10.3168/jds.2016-11770
}}
* {{medline-title
|title=The thyroid hormone receptor β induces DNA damage and premature senescence.
|date=06.01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24395638
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882795
}}
==TLR5==
 
* {{medline-title
|title=Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30089902
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0395-5
}}
* {{medline-title
|title=Direct Regulation of [[TLR5]] Expression by Caveolin-1.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26615831
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697003
}}
* {{medline-title
|title=Flagellin-dependent [[TLR5]]/caveolin-1 as a promising immune activator in immunosenescence.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26223660
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568978
}}
==TNC==
 
* {{medline-title
|title=Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging.
|date=18.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33217999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698786
}}
* {{medline-title
|title=Tenascin-C expression controls the maturation of articular cartilage in mice.
|date=17.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32066496
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027060
}}
* {{medline-title
|title=Effects of hydrothermal aging, thermal cycling, and water storage on the mechanical properties of a machinable resin-based composite containing nano-zirconia fillers.
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31877525
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2019.103522
}}
==TPH1==
 
* {{medline-title
|title=[i]Lactobacillus plantarum[/i] DR7 improved brain health in aging rats via the serotonin, inflammatory and apoptosis pathways.
|date=02.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33245015
|full-text-url=https://sci-hub.do/10.3920/BM2019.0200
}}
* {{medline-title
|title=Ageing and gastrointestinal sensory function: altered colonic mechanosensory and chemosensory function in the aged mouse.
|date=15.08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26592729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983623
}}
* {{medline-title
|title=Use of the RatLoft decreases pup mortality in lactating mice.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26568578
|full-text-url=https://sci-hub.do/10.1177/0023677215617388
}}
==TRAF3==
 
* {{medline-title
|title=[[TRAF3]], a Target of MicroRNA-363-3p, Suppresses Senescence and Regulates the Balance Between Osteoblastic and Adipocytic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells.
|date=01.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32111144
|full-text-url=https://sci-hub.do/10.1089/scd.2019.0276
}}
* {{medline-title
|title=TGFβ-induced degradation of [[TRAF3]] in mesenchymal progenitor cells causes age-related osteoporosis.
|date=26.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31243287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595054
}}
* {{medline-title
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes.
|date=12.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941
}}
==TRAP1==
 
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
* {{medline-title
|title=Changes in Drosophila mitochondrial proteins following chaperone-mediated lifespan extension confirm a role of Hsp22 in mitochondrial UPR and reveal a mitochondrial localization for cathepsin D.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26930296
|full-text-url=https://sci-hub.do/10.1016/j.mad.2016.02.011
}}
* {{medline-title
|title=Mitochondrial chaperone [[TRAP1]] activates the mitochondrial UPR and extends healthspan in Drosophila.
|date=11-12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25265088
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310785
}}
==TRPC4==
 
* {{medline-title
|title=Alterations of store-operated calcium entry and cyclopiazonic acid-induced endothelium-derived relaxations in aging rat thoracic aorta.
|date=01.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28639863
|full-text-url=https://sci-hub.do/10.1556/036.103.2016.2.2
}}
* {{medline-title
|title=Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27854075
|full-text-url=https://sci-hub.do/10.1007/s11010-016-2884-x
}}
* {{medline-title
|title=Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24496748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209016
}}
==TRPV5==
 
* {{medline-title
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
}}
* {{medline-title
|title=Lifelong challenge of calcium homeostasis in male mice lacking [[TRPV5]] leads to changes in bone and calcium metabolism.
|date=03.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27102152
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041880
}}
* {{medline-title
|title=Molecular aspects of intestinal calcium absorption.
|date=21.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26109800
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476875
}}
==TUBB3==
 
* {{medline-title
|title=Evaluation of tubulin β-3 as a novel senescence-associated gene in melanocytic malignant transformation.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28024114
|full-text-url=https://sci-hub.do/10.1111/pcmr.12572
}}
* {{medline-title
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853
}}
* {{medline-title
|title=GBM-associated mutations and altered protein expression are more common in young patients.
|date=25.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491
}}
==TXNRD2==
 
* {{medline-title
|title=Wogonin induces cellular senescence in breast cancer via suppressing [[TXNRD2]] expression.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32671444
|full-text-url=https://sci-hub.do/10.1007/s00204-020-02842-y
}}
* {{medline-title
|title=Loss of [[IDH2]] Accelerates Age-related Hearing Loss in Male Mice.
|date=22.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864918
}}
* {{medline-title
|title=Mitochondrial thioredoxin reductase 2 is elevated in long-lived primate as well as rodent species and extends fly mean lifespan.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28474396
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506402
}}
==TYROBP==
 
* {{medline-title
|title=[[TREM2]] triggers microglial density and age-related neuronal loss.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266
}}
* {{medline-title
|title=Identification of a conserved gene signature associated with an exacerbated inflammatory environment in the hippocampus of aging rats.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28085212
|full-text-url=https://sci-hub.do/10.1002/hipo.22703
}}
* {{medline-title
|title=Phenotypic characteristics of aged [[CD4]]  [[CD28]]  T lymphocytes are determined by changes in the whole-genome DNA methylation pattern.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28026094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334526
}}
==UBE3A==
 
* {{medline-title
|title=Delayed loss of [[UBE3A]] reduces the expression of Angelman syndrome-associated phenotypes.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31143434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532248
}}
* {{medline-title
|title=Seizure-like activity in a juvenile Angelman syndrome mouse model is attenuated by reducing Arc expression.
|date=21.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25848016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413330
}}
* {{medline-title
|title=Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824446
|full-text-url=https://sci-hub.do/10.1136/bjsports-2014-094073
}}
==UHRF1==
 
* {{medline-title
|title=MLL3 promotes the senescence of esophageal squamous cell carcinoma.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30881012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402438
}}
* {{medline-title
|title=[[UHRF1]] is required for basal stem cell proliferation in response to airway injury.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28626588
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468773
}}
* {{medline-title
|title=The Ubiquitin-like with PHD and Ring Finger Domains 1 ([[UHRF1]])/DNA Methyltransferase 1 ([[DNMT1]]) Axis Is a Primary Regulator of Cell Senescence.
|date=03.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28100769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339756
}}
==USP7==
 
* {{medline-title
|title=Deubiquitinase [[USP7]] regulates [i]Drosophila[/i] aging through ubiquitination and autophagy.
|date=20.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33221768
|full-text-url=https://sci-hub.do/10.18632/aging.104067
}}
* {{medline-title
|title=Disruption of the Phosphate Transporter Pit1 in Hepatocytes Improves Glucose Metabolism and Insulin Signaling by Modulating the [[USP7]]/[[IRS1]] Interaction.
|date=06.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27568561
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2016.08.012
}}
* {{medline-title
|title=The C. elegans Ortholog of [[USP7]] controls DAF-16 stability in Insulin/IGF-1-like signaling.
|date=10-12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27123371
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826154
}}
==WLS==
 
* {{medline-title
|title=Evaluation of three statistical prediction models for forensic age prediction based on DNA methylation.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477092
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.02.008
}}
* {{medline-title
|title=The Influence of Social Conditions Across the Life Course on the Human Gut Microbiota: A Pilot Project With the Wisconsin Longitudinal Study.
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28444239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926979
}}
* {{medline-title
|title=Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study.
|date=01.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27616567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837042
}}
==WNT3A==
 
* {{medline-title
|title=Chronic WNT/β-catenin signaling induces cellular senescence in lung epithelial cells.
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109549
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2020.109588
}}
* {{medline-title
|title=[[WNT3A]] accelerates delayed alveolar bone repair in ovariectomized mice.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31338519
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007703
}}
* {{medline-title
|title=WNT-activated bone grafts repair osteonecrotic lesions in aged animals.
|date=27.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29079746
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660190
}}
==WT1==
 
* {{medline-title
|title=Age and weight at first mating affects plasma leptin concentration but no effects on reproductive performance of gilts.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31602307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778857
}}
* {{medline-title
|title=Epigenetic Aging Signatures Are Coherently Modified in Cancer.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26110659
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482318
}}
* {{medline-title
|title=A novel cell-penetrating peptide derived from [[WT1]] enhances p53 activity, induces cell senescence and displays antimelanoma activity in xeno- and syngeneic systems.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24490140
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907745
}}
==XRCC3==
 
* {{medline-title
|title=Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes.
|date=19.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26477511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609912
}}
* {{medline-title
|title=Subclinical carotid atherosclerosis and early vascular aging from long-term low-dose ionizing radiation exposure: a genetic, telomere, and vascular ultrasound study in cardiac catheterization laboratory staff.
|date=20.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25907089
|full-text-url=https://sci-hub.do/10.1016/j.jcin.2014.12.233
}}
* {{medline-title
|title=[Role of DNA repair genes in radiation-induced changes of lifespan of Drosophila melanogaster].
|date=09-10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25775840
 
}}
==ZCWPW1==
 
* {{medline-title
|title=Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28269768
|full-text-url=https://sci-hub.do/10.3233/JAD-160774
}}
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
}}
Пожалуйста, учтите, что любой ваш вклад в проект «hpluswiki» может быть отредактирован или удалён другими участниками. Если вы не хотите, чтобы кто-либо изменял ваши тексты, не помещайте их сюда.
Вы также подтверждаете, что являетесь автором вносимых дополнений, или скопировали их из источника, допускающего свободное распространение и изменение своего содержимого (см. Hpluswiki:Авторские права). НЕ РАЗМЕЩАЙТЕ БЕЗ РАЗРЕШЕНИЯ ОХРАНЯЕМЫЕ АВТОРСКИМ ПРАВОМ МАТЕРИАЛЫ!
Отменить Справка по редактированию (в новом окне)

Шаблон, используемый на этой странице:

Источник — https://transhumanist.ru/Aging_genes_3-9