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|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. ...ts support the hypothesis that microglia are key players involved in human aging and neurodegenerative diseases, and suggest that mouse models should be app ...

...Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease. ...xpression of [[DIAPH1]] in the human medial temporal cortex during healthy aging and AD. We used semi-quantitative immunohistochemistry in the human medial ...

|title=A novel structure associated with aging is augmented in the [[DPP6]]-KO mouse brain. ...rmal presynaptic structures associated with several markers of Alzheimer's disease. ...

...es to atherosclerosis. HDL loses their beneficial properties in ageing and disease states. Novel pathways may present new therapeutic avenues to restore their |mesh-terms=* Aging ...

...defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. ...ng a mechanism by which 50% reduction of T-box transcription factors cause disease. Direct and cooperative transactivation of the ANF and cx40 promoters by Tb ...

...[[TBC1D2]], [[GALNT18]], ABCC1[/i] and [i]SRCIN1[/i] genes were identified as potential candidates. [i]SIAH3[/i] rs11620312-C carriers were associated wi * Aging ...

|title=A roadmap for the genetic analysis of renal aging. ...iversity will facilitate the identification of genes associated with renal aging by enabling high-resolution genetic mapping while also allowing the control ...

...dulated by ORY-2001 are differentially expressed in Late Onset Alzheimer's Disease. Most strikingly, the amplifier of inflammation [[S100A9]] is highly expres |mesh-terms=* Aging ...

...terogeneous disease with a different aetiology in cases with early or late disease onset. * Aging ...

...ecreased bone mineral density in Japanese patients with inflammatory bowel disease. ...nia (minimum P = 5.86E - 07). Interestingly, none of the known loci showed a significant association with BMD. Although clinical risk factors for low BM ...

...rofiling identifies [[MRPS6]] as a possible candidate gene for Parkinson's disease. ...ic disorders. The top gene reported here is the nuclear encoded [[MRPS6]], a building block of the human mitoribosome of the oxidative phosphorylation s ...

...knowledge on genes that regulate LTL and their impact on human health and disease. * age-related disease ...

...iates the beneficial effects of pridopidine in a mouse model of Huntington disease. ...s a new potential mechanism of action for pridopidine, highlighting S1R as a potential target for HD therapy. Upregulation of striatal proteins that reg ...

...knowledge on genes that regulate LTL and their impact on human health and disease. * age-related disease ...

|title=Age-dependent disease expression determines remodeling of the retinal mosaic in carriers of [[RPG ...as mutant photoreceptors die. In the late-onset form (XLPRA1), patches of disease persisted until later ages. ...

|title=Prevalence and associated metabolic factors of fatty liver disease in the elderly. ...in the elderly, and is broadly related to the same metabolic risk factors as in the non-elderly. However, female-sex is no longer protective with increa ...

...ions with a premature stop codon would be associated with disease onset at a younger age.  * Aging ...

...otentially Contribute to the Regulation of Molecular Signaling Networks in Aging. ...entions that could reverse certain aging processes and slow development of aging-related diseases. ...

...rmeability, more than lesion permeability, may serve as a biomarker of CCM disease activity, and help calibrate potential drug therapy. * Aging ...

...[[TBC1D2]], [[GALNT18]], ABCC1[/i] and [i]SRCIN1[/i] genes were identified as potential candidates. [i]SIAH3[/i] rs11620312-C carriers were associated wi * Aging ...