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Aging genes 1-2: различия между версиями

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Aging genes 1-2 (править)

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* [[Aging genes 1-2‎‎|Genes with 1-2 publications]]
* [[Aging genes 1-2‎‎|Genes with 1-2 publications]]


==ABCA1==
==AACS==
 
* {{medline-title
|title=Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study.
|date=07.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33170149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695390
}}
* {{medline-title
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
==ABCC2==
 
* {{medline-title
|title=Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27103634
|full-text-url=https://sci-hub.do/10.1124/dmd.115.068577
}}
* {{medline-title
|title=Developmental characteristics of urinary coproporphyrin I/(I  III) ratio.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26920082
|full-text-url=https://sci-hub.do/10.1111/ped.12965
}}
==ABCC6==
 
* {{medline-title
|title=[i][[ABCC6]][/i] knockdown in HepG2 cells induces a senescent-like cell phenotype.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28536638
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415800
}}
* {{medline-title
|title=Changes in dermal fibroblasts from Abcc6(-/-) mice are present before and after the onset of ectopic tissue mineralization.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24670382
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057957
}}
==ABI3==


* {{medline-title
* {{medline-title
|title=Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension.
|title=Arabidopsis seed-specific vacuolar aquaporins are involved in maintaining seed longevity under the control of ABSCISIC ACID INSENSITIVE 3.
|date=01.07.2019
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109455
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26019256
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.08.027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507774
}}
}}
* {{medline-title
* {{medline-title
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.
|title=A forward genetic approach in Arabidopsis thaliana identifies a RING-type ubiquitin ligase as a novel determinant of seed longevity.
|date=08.2018
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24388521
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2013.11.004
}}
}}
==ACACA==
==ACACA==
Строка 35: Строка 77:
|full-text-url=https://sci-hub.do/10.1016/j.bone.2018.04.014
|full-text-url=https://sci-hub.do/10.1016/j.bone.2018.04.014
}}
}}
==ACAT1==
==ACAN==


* {{medline-title
* {{medline-title
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|title=MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway.
|date=06.2019
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30987676
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769
}}
* {{medline-title
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823
}}
==ACOX1==
 
* {{medline-title
|title=Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677513
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2019.01.005
}}
}}
* {{medline-title
* {{medline-title
|title=Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging.
|title=Acetylation reduces [[SOX9]] nuclear entry and [[ACAN]] gene transactivation in human chondrocytes.
|date=2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765501
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26910618
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854920
}}
}}
==ACTA1==
==ACTA1==
Строка 91: Строка 119:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660190
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660190
}}
}}
==ADAM17==
==ACVR1==


* {{medline-title
* {{medline-title
|title=ACE2/[[ADAM17]]/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19.
|title=Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome.
|date=2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31998237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575774
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966325
}}
* {{medline-title
|title=BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence.
|date=15.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27794120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135304
}}
==ADH1B==
 
* {{medline-title
|title=Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466069
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2018.11.007
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Relationships of alcohol dehydrogenase 1B ([[ADH1B]]) and aldehyde dehydrogenase 2 ([[ALDH2]]) genotypes with alcohol sensitivity, drinking behavior and problem drinking in Japanese older men.
|date=25.07.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26825972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823221
}}
}}
==ADH5==
==ADH5==
Строка 119: Строка 161:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103690
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103690
}}
}}
==AGER==
==ADIPOQ==


* {{medline-title
* {{medline-title
|title=Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model.
|title=Determination of the Mechanisms that Cause Sarcopenia through cDNA Microarray.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28555711
|full-text-url=https://sci-hub.do/10.14283/jfa.2017.13
}}
* {{medline-title
|title=Contribution of adiponectin and its type 1 receptor to age-related hearing impairment.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25911279
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.02.030
}}
==ADIPOR1==
 
* {{medline-title
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
}}
* {{medline-title
|title=Contribution of adiponectin and its type 1 receptor to age-related hearing impairment.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25911279
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.02.030
}}
==ADNP==
 
* {{medline-title
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
}}
* {{medline-title
|title=[[ADNP]]: A major autism mutated gene is differentially distributed (age and gender) in the songbird brain.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25895853
|full-text-url=https://sci-hub.do/10.1016/j.peptides.2015.04.008
}}
==ADRA2B==
 
* {{medline-title
|title=Aging and the Combined effects of [[ADRA2B]] and CB1 deletions on Affective Working Memory.
|date=11.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30858399
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411975
}}
* {{medline-title
|title=Aging and the genetic road towards the positivity effect in memory.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27350108
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.06.011
}}
==AGER==
 
* {{medline-title
|title=Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model.
|date=01.10.2019
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31575929
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31575929
Строка 147: Строка 245:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704092
}}
}}
==AGT==
==AHCY==


* {{medline-title
|title=SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence.
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441382
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469683
}}
* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
Строка 161: Строка 253:
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
==ALKBH8==
* {{medline-title
|title=Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila.
|date=15.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27313316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926864
}}
==AIDA==


* {{medline-title
* {{medline-title
|title=Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming .
|title=Identification of Postharvest Senescence Regulators Through Map-Based Cloning Using Detached Arabidopsis Inflorescences as a Model Tissue.
|date=01.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392668
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904832
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-7672-0_17
}}
}}
* {{medline-title
* {{medline-title
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|title=Interaction of DHPG-LTD and synaptic-LTD at senescent [[CA3]]-[[CA1]] hippocampal synapses.
|date=2018
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24390964
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959216
}}
}}
==AMT==
==AKT3==


* {{medline-title
* {{medline-title
|title=A multi-method comparison of autobiographical memory impairments amongst younger and older adults.
|title=Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma.
|date=12.03.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162531
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097674
|full-text-url=https://sci-hub.do/10.1080/13607863.2020.1729338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135677
}}
}}
* {{medline-title
* {{medline-title
|title=Autobiographical Memory From Different Life Stages in Individuals With Obstructive Sleep Apnea.
|title=MicroRNA-22 induces endothelial progenitor cell senescence by targeting [[AKT3]].
|date=03.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25323119
|full-text-url=https://sci-hub.do/10.1017/S1355617718001091
|full-text-url=https://sci-hub.do/10.1159/000366358
}}
}}
==ANGPTL2==
==AKTIP==


* {{medline-title
* {{medline-title
|title=Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study.
|title=Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits.
|date=01.05.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31840173
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29635765
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052474
}}
* {{medline-title
|title=The telomeric protein [[AKTIP]] interacts with A- and B-type lamins and is involved in regulation of cellular senescence.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27512140
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008010
}}
==ALKBH8==
 
* {{medline-title
|title=Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming .
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765888
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904832
}}
* {{medline-title
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
 
}}
==ANGPTL2==
 
* {{medline-title
|title=Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study.
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31840173
|full-text-url=https://sci-hub.do/10.1093/ndt/gfz236
|full-text-url=https://sci-hub.do/10.1093/ndt/gfz236
}}
}}
Строка 217: Строка 343:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==APOA5==
==ANK3==
 
* {{medline-title
|title=Age-related atrophy of cortical thickness and genetic effect of [[ANK3]] gene in first episode MDD patients.
|date=26.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32911427
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490581
}}
* {{medline-title
|title=Mood, stress and longevity: convergence on [[ANK3]].
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27217151
|full-text-url=https://sci-hub.do/10.1038/mp.2016.65
}}
==AP2B1==


* {{medline-title
* {{medline-title
|title=Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.
|title=Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice.
|date=03.2019
|date=20.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30700132
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31860870
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399473
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949063
}}
* {{medline-title
|title=Investigating the specific core genetic-and-epigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells.
|date=23.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26895224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890987
}}
==APOB==
 
* {{medline-title
|title=Autophagy-mediated longevity is modulated by lipoprotein biogenesis.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26671266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836030
}}
* {{medline-title
|title=Exome sequencing of three cases of familial exceptional longevity.
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25116423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326919
}}
==APOL1==
 
* {{medline-title
|title=[[APOL1]] Risk Alleles Are Associated with Exaggerated Age-Related Changes in Glomerular Number and Volume in African-American Adults: An Autopsy Study.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26038529
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657832
}}
}}
* {{medline-title
* {{medline-title
|title=Longitudinal interaction between [[APOA5]] -1131T>C and overweight in the acceleration of age-related increase in arterial stiffness through the regulation of circulating triglycerides.
|title=Apolipoprotein L1, income and early kidney damage.
|date=02.2019
|date=10.02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25884165
|full-text-url=https://sci-hub.do/10.1038/s41440-018-0137-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361142
}}
}}
==APPL2==
==APPL2==
Строка 244: Строка 412:
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28965332
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28965332
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0785-y
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0785-y
}}
==AQP1==
* {{medline-title
|title=Blue Light Induces Down-Regulation of Aquaporin 1, 3, and 9 in Human Keratinocytes.
|date=03.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400272
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262559
}}
* {{medline-title
|title=[Age-related changes of water transport by corneal endothelial cells in rats.]
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322730
}}
}}
==AQP3==
==AQP3==
Строка 273: Строка 427:


}}
}}
==AREG==
==ARID1B==


* {{medline-title
* {{medline-title
|title=Targeting amphiregulin ([[AREG]]) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
|title=A 69-year-old woman with Coffin-Siris syndrome.
|date=12.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31493351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826133
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.38844
}}
}}
* {{medline-title
* {{medline-title
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|title=SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.
|date=2019
|date=01.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27737960
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088567
}}
}}
==ARID1A==
==ARX==


* {{medline-title
* {{medline-title
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|title=Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.
|date=10.2019
|date=07.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28215845
|full-text-url=https://sci-hub.do/10.1002/path.5314
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358097
}}
* {{medline-title
|title=Acacetin 7-O-α-l-rhamnopyranosyl (1-2) β-D-xylopyranoside Elicits Life-span Extension and Stress Resistance in Caenorhabditis elegans.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26433219
|full-text-url=https://sci-hub.do/10.1093/gerona/glv173
}}
==ASXL2==
 
* {{medline-title
|title=Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329260
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013013
}}
}}
* {{medline-title
* {{medline-title
|title=[[ARID1A]] suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[[[CDKN2A]]]] regulatory axis.
|title=The [[BAP1]]/[[ASXL2]] Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.
|date=18.11.2017
|date=27.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942143
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416890
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.099
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661380
}}
}}
==ATG12==
==ATF2==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium.
|date=2019
|date=01.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360953
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915954
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Prmt7 Deficiency Causes Reduced Skeletal Muscle Oxidative Metabolism and Age-Related Obesity.
|date=09.2017
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27207521
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://sci-hub.do/10.2337/db15-1500
}}
}}
==ATG3==
==ATF7==


* {{medline-title
* {{medline-title
|title=Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells.
|title=Stress-induced and [[ATF7]]-dependent epigenetic change influences cellular senescence.
|date=01.04.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32244623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31294895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235898
|full-text-url=https://sci-hub.do/10.1111/gtc.12713
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species.
|date=09.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28632756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478092
}}
}}
==ATG9A==
==ATG9A==
Строка 342: Строка 510:
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28981097
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28981097
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680584
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680584
}}
==ATP1A2==
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
* {{medline-title
|title=The Influence of Na( ), K( )-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27313535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890531
}}
==ATP6V1E1==
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
* {{medline-title
|title=Chemical screening identifies [[ATM]] as a target for alleviating senescence.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28346404
|full-text-url=https://sci-hub.do/10.1038/nchembio.2342
}}
}}
==ATP7A==
==ATP7A==
Строка 357: Строка 553:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326685
}}
}}
==B2M==
==AXL==


* {{medline-title
* {{medline-title
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes.
|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells.
|date=03.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468
|full-text-url=https://sci-hub.do/10.1111/pcmr.12811
}}
}}
* {{medline-title
* {{medline-title
|title=Association between serum β2-microglobulin levels and frailty in an elderly Chinese population: results from RuLAS.
|title=CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of [[GRN]]/P[[GRN]].
|date=2017
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081654
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28189700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652941
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389672
}}
}}
==B4GALT1==
==B4GALT1==
Строка 385: Строка 581:
|full-text-url=https://sci-hub.do/10.1007/978-981-13-2835-0_17
|full-text-url=https://sci-hub.do/10.1007/978-981-13-2835-0_17
}}
}}
==BAK1==
==BAG3==


* {{medline-title
* {{medline-title
|title=Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon.
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
|date=23.09.2020
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32710818
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529960
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans.
|date=09.2017
|date=06.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26337083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745765
}}
==BANF1==
 
* {{medline-title
|title=An additional case of Néstor-Guillermo progeria syndrome diagnosed in early childhood.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32783369
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.61777
}}
* {{medline-title
|title=Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation.
|date=12.12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25495845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266902
}}
==BARD1==
 
* {{medline-title
|title=BRCA1 and [[BARD1]] mediate apoptotic resistance but not longevity upon mitochondrial stress in [i]Caenorhabditis elegans[/i].
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30366941
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280797
}}
* {{medline-title
|title=The Histone Variant MacroH2A1 Is a [[BRCA1]] Ubiquitin Ligase Substrate.
|date=30.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28564596
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507409
}}
==BCL11B==
 
* {{medline-title
|title=Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989724
}}
* {{medline-title
|title=Age-related profiling of DNA methylation in CD8  T cells reveals changes in immune response and transcriptional regulator genes.
|date=19.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26286994
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541364
}}
}}
==BCL6==
==BCL6==
Строка 413: Строка 651:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
}}
}}
==BECN1==
==BMPR1B==


* {{medline-title
* {{medline-title
|title=Calpain-dependent Beclin1 cleavage stimulates senescence-associated cell death in HT22 hippocampal cells under the oxidative stress conditions.
|title=Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes.
|date=14.05.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30807795
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503129
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2019.02.036
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.08.018
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-[[ULK1]] signaling pathway.
|title=Dysregulation of granulosal bone morphogenetic protein receptor 1B density is associated with reduced ovarian reserve and the age-related decline in human fertility.
|date=04.2018
|date=15.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26805635
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810242
|full-text-url=https://sci-hub.do/10.1016/j.mce.2016.01.016
}}
}}
==BGN==
==BRD2==


* {{medline-title
* {{medline-title
|title=Alterations of local functional connectivity in lifespan: A resting-state fMRI study.
|title=Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice.
|date=07.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32462815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32559200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304595
}}
}}
* {{medline-title
* {{medline-title
|title=Exploring variability in basal ganglia connectivity with functional MRI in healthy aging.
|title=Genetic architecture differences between pediatric and adult-onset inflammatory bowel diseases in the Polish population.
|date=12.2018
|date=23.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29442271
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28008999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302142
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180213
}}
}}
==BIN1==
==BTC==


* {{medline-title
* {{medline-title
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.
|title=Behavioral tagging and capture: long-term memory decline in middle-aged rats.
|date=20.03.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29609080
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964067
}}
}}
* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=Estimates of genetic parameters for content of boar taint compounds in adipose tissue of intact males at 160 and 220 days of age.
|date=28.03.2018
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26440326
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://sci-hub.do/10.2527/jas.2015-9252
}}
}}
==BMF==
==BTK==


* {{medline-title
* {{medline-title
|title=lncRNA-ES3/miR-34c-5p/[[BMF]] axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs.
|title=Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition.
|date=17.01.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31736210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366973
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974713
}}
}}
* {{medline-title
* {{medline-title
|title=Aging, hematopoiesis, and the myelodysplastic syndromes.
|title=[[BTK]] suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling.
|date=08.12.2017
|date=22.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29222239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28915637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593608
}}
}}
==BMP15==
==BTLA==


* {{medline-title
* {{medline-title
|title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro.
|title=Combinatorial approach to cancer immunotherapy: strength in numbers.
|date=01.2019
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27256570
|full-text-url=https://sci-hub.do/10.1002/mrd.23079
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608090
}}
}}
* {{medline-title
* {{medline-title
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|title=[[BTLA]] expression declines on B cells of the aged and is associated with low responsiveness to the trivalent influenza vaccine.
|date=18.10.2017
|date=14.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26277622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637297
}}
}}
==BNIP3==
==CA12==


* {{medline-title
* {{medline-title
|title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training.
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|date=01.10.2019
|date=26.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
}}
}}
* {{medline-title
* {{medline-title
|title=Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training.
|title=Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration.
|date=01.10.2018
|date=04.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030137
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473691
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431421
}}
}}
==BTK==
==CASK==


* {{medline-title
* {{medline-title
|title=Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition.
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats.
|date=01.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31736210
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974713
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001
}}
* {{medline-title
|title=[[BTK]] suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling.
|date=22.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28915637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593608
}}
}}
==C9orf72==
* {{medline-title
* {{medline-title
|title=Carriership of two copies of [[C9orf72]] hexanucleotide repeat intermediate-length alleles is a risk factor for ALS in the Finnish population.
|title=Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.
|date=09.11.2020
|date=01.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168078
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28013231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654756
}}
* {{medline-title
|title=[[C9]]orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons.
|date=29.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705968
}}
}}
==CAST==
==CAST==
Строка 539: Строка 763:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992026
}}
}}
==CBL==
==CBX7==


* {{medline-title
* {{medline-title
|title=Effects of cerebrolysin on nerve growth factor system in the aging rat brain.
|title=Integrin Beta 3 Regulates Cellular Senescence by Activating the TGF-β Pathway.
|date=2017
|date=07.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28273461
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701766
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357738
}}
}}
* {{medline-title
* {{medline-title
|title=Skeletal Muscle CAP Expression Increases after Dietary Restriction and Aerobic Training in Women with a History of Gestational Diabetes.
|title=[[CBX7]] and miR-9 are part of an autoregulatory loop controlling p16(INK) (4a).
|date=2016
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28989819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416703
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628746
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693451
}}
}}
==CCL17==
==CBX8==


* {{medline-title
* {{medline-title
|title=Aging and chronic high-fat feeding negatively affects kidney size, function, and gene expression in CTRP1-deficient mice.
|title=[[PIM1]]-catalyzed [[CBX8]] phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast.
|date=21.10.2020
|date=27.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33085906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29763603
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00139.2020
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.05.070
}}
}}
* {{medline-title
* {{medline-title
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism.
|title=[[CBX8]] antagonizes the effect of Sirtinol on premature senescence through the AKT-RB-[[E2F1]] pathway in K562 leukemia cells.
|date=21.05.2019
|date=22.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26718407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.12.070
}}
}}
==CCL20==
==CCL13==


* {{medline-title
* {{medline-title
|title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors.
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|date=06.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272174
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|full-text-url=https://sci-hub.do/10.1016/j.antiviral.2020.104784
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly.
|title=Differential Gene Expression Profiles Reflecting Macrophage Polarization in Aging and Periodontitis Gingival Tissues.
|date=02.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29193757
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26397131
|full-text-url=https://sci-hub.do/10.1002/mnfr.201700307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786741
}}
}}
==CCL21==
==CCL17==


* {{medline-title
* {{medline-title
|title=[[CCL21]]/[[CCR7]] axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
|title=Aging and chronic high-fat feeding negatively affects kidney size, function, and gene expression in CTRP1-deficient mice.
|date=26.03.2019
|date=21.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30914733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33085906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435673
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00139.2020
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism.
|date=01.2018
|date=21.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237
}}
}}
==CCL24==
==CCL24==
Строка 609: Строка 833:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707671
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707671
}}
}}
==CCN3==
==CCN2==


* {{medline-title
* {{medline-title
|title=[[CCN3]] Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta.
|title=[[CCN2]] induces cellular senescence in fibroblasts.
|date=2020
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304321
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27752926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362572
}}
}}
* {{medline-title
* {{medline-title
|title=[[CCN3]] (NOV) Drives Degradative Changes in Aging Articular Cartilage.
|title=Generation and Analysis of Cartilage-Specific [[CCN2]] Overexpression in Transgenic Mice.
|date=13.10.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066270
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27734391
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593953
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-6430-7_32
}}
==CCN4==
 
* {{medline-title
|title=CCN proteins as potential actionable targets in scleroderma.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30329180
|full-text-url=https://sci-hub.do/10.1111/exd.13806
}}
* {{medline-title
|title=[[WNT1]]-induced Secreted Protein-1 (WI[[SP1]]), a Novel Regulator of Bone Turnover and Wnt Signaling.
|date=29.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25864198
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447973
}}
==CCND1==
 
* {{medline-title
|title=Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells.
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592933
|full-text-url=https://sci-hub.do/10.1016/j.archoralbio.2020.104819
}}
* {{medline-title
|title=Expansion of adipose tissue-derived stromal cells at "physiologic" hypoxia attenuates replicative senescence.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28589682
|full-text-url=https://sci-hub.do/10.1002/cbf.3267
}}
}}
==CCNG2==
==CCNG2==
Строка 637: Строка 889:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
}}
}}
==CCR6==
==CD160==


* {{medline-title
* {{medline-title
|title=Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells.
|title=Age-related changes in the gene expression profile of antigen-specific mouse CD8  T cells can be partially reversed by blockade of the BTLA/[[CD160]] pathways during vaccination.
|date=07.2019
|date=09.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696983
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27922818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270668
}}
* {{medline-title
|title=T cells in multiple myeloma display features of exhaustion and senescence at the tumor site.
|date=03.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27809856
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093947
}}
==CD46==
 
* {{medline-title
|title=Soluble forms of [[CD46]] are detected in Bos taurus plasma and neutralize BVDV, the bovine pestivirus.
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27865262
|full-text-url=https://sci-hub.do/10.1016/j.cimid.2016.09.001
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|title=Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating [[CD200]]-[[CD200]]R interaction involve the cannabinoid system.
|date=19.01.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24588829
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157566
}}
}}
==CD22==
==CDC25A==


* {{medline-title
* {{medline-title
|title=[[CD22]] blockade restores homeostatic microglial phagocytosis in ageing brains.
|title=Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage.
|date=04.2019
|date=10.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6574119
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600899
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves.
|title=Nickel-induced HIF-1α promotes growth arrest and senescence in normal human cells but lacks toxic effects in transformed cells.
|date=03.2018
|date=15.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28552779
|full-text-url=https://sci-hub.do/10.24425/119039
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568485
}}
}}
==CDK1==
==CDH1==


* {{medline-title
* {{medline-title
|title=MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging.
|title=Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation.
|date=02.2020
|date=15.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31848878
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32010971
|full-text-url=https://sci-hub.do/10.1007/s12015-019-09924-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496346
}}
* {{medline-title
|title=A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407996
|full-text-url=https://sci-hub.do/10.1016/j.jval.2017.01.006
}}
}}
==CDKN1B==
* {{medline-title
* {{medline-title
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
}}
* {{medline-title
|title=RNA methyltransferase [[NSUN2]] promotes stress-induced HUVEC senescence.
|date=12.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26992231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991368
}}
==CDKN1C==
 
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
}}
* {{medline-title
|title=Expansion of adipose tissue-derived stromal cells at "physiologic" hypoxia attenuates replicative senescence.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28589682
|full-text-url=https://sci-hub.do/10.1002/cbf.3267
}}
}}
==CDKN2B==
==CDKN2B==
Строка 693: Строка 987:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488111
}}
}}
==CFD==
==CDR1==


* {{medline-title
* {{medline-title
|title=Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D.
|title=Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786517
}}
* {{medline-title
|title=Neuro-degeneration profile of Alzheimer's patients: A brain morphometry study.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28459000
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397580
}}
==CDX2==
 
* {{medline-title
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
}}
* {{medline-title
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853
}}
==CEBPB==
 
* {{medline-title
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
* {{medline-title
|title=The microRNA miR-17-3p inhibits mouse cardiac fibroblast senescence by targeting Par4.
|date=15.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25472717
|full-text-url=https://sci-hub.do/10.1242/jcs.158360
}}
==CELF1==
 
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
==CES2==
 
* {{medline-title
|title=Age-Dependent Absolute Abundance of Hepatic Carboxylesterases ([[CES1]] and [[CES2]]) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27895113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267516
}}
* {{medline-title
|title=Age-Dependent Human Hepatic Carboxylesterase 1 ([[CES1]]) and Carboxylesterase 2 ([[CES2]]) Postnatal Ontogeny.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26825642
|full-text-url=https://sci-hub.do/10.1124/dmd.115.068957
}}
==CFD==
 
* {{medline-title
|title=Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D.
|date=07.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026383
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026383
Строка 706: Строка 1070:
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165372
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165372
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201827
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201827
}}
==CFP==
* {{medline-title
|title=Proteopathic tau seeding predicts tauopathy in vivo.
|date=14.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25261551
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205609
}}
* {{medline-title
|title=Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo.
|date=04.02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24449915
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918838
}}
}}
==CHI3L1==
==CHI3L1==
Строка 720: Строка 1098:
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247206
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247206
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2019.146305
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2019.146305
}}
==CHIA==
* {{medline-title
|title=Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets.
|date=26.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30486328
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316572
}}
* {{medline-title
|title=Chia Oil-Enriched Restructured Pork Effects on Oxidative and Inflammatory Status of Aged Rats Fed High Cholesterol/High Fat Diets.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28294699
|full-text-url=https://sci-hub.do/10.1089/jmf.2016.0161
}}
==CHL1==
* {{medline-title
|title=Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B.
|date=07.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182634
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687901
}}
* {{medline-title
|title=Age-dependent loss of parvalbumin-expressing hippocampal interneurons in mice deficient in [[CHL1]], a mental retardation and schizophrenia susceptibility gene.
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26285062
|full-text-url=https://sci-hub.do/10.1111/jnc.13284
}}
}}
==CHM==
==CHM==
Строка 735: Строка 1141:
|full-text-url=https://sci-hub.do/10.4268/cjcmm20162105
|full-text-url=https://sci-hub.do/10.4268/cjcmm20162105
}}
}}
==CISD2==
==CLC==


* {{medline-title
* {{medline-title
|title=[[CISD2]] Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells-As a Potential Therapeutic Target for Neurodegenerative Dementia.
|title=Impact of Intervention to Improve Nursing Home Resident-Staff Interactions and Engagement.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33005144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479185
}}
* {{medline-title
|title=Protective Effects of [[CISD2]] and Influence of Curcumin on [[CISD2]] Expression in Aged Animals and Inflammatory Cell Model.
|date=25.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30934593
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470567
}}
==CLC==
 
* {{medline-title
|title=Impact of Intervention to Improve Nursing Home Resident-Staff Interactions and Engagement.
|date=13.07.2018
|date=13.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718195
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718195
Строка 762: Строка 1154:
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29699920
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29699920
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2018.04.068
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2018.04.068
}}
==CLEC3B==
* {{medline-title
|title=[[CLEC3B]] p.S106G Mutant in a Caucasian Population of Successful Neurological Aging.
|date=16.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494029
}}
* {{medline-title
|title=Exome-wide Association Study Identifies [[CLEC3B]] Missense Variant p.S106G as Being Associated With Extreme Longevity in East Asian Populations.
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27154906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861862
}}
}}
==CLPP==
==CLPP==
Строка 777: Строка 1183:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052477
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052477
}}
}}
==COL3A1==
==CNP==
 
* {{medline-title
|title=Environmental Enrichment Elicits a Transient Rise of Bioactive C-Type Natriuretic Peptide in Young but Not Aged Rats.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30072880
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060231
}}
* {{medline-title
|title=In aging, the vulnerability of rat brain mitochondria is enhanced due to reduced level of 2',3'-cyclic nucleotide-3'-phosphodiesterase ([[CNP]]) and subsequently increased permeability transition in brain mitochondria in old animals.
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25277077
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2014.09.008
}}
==CNTF==


* {{medline-title
* {{medline-title
|title=Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season.
|title=Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha.
|date=21.12.2019
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31864349
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30861131
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925900
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656591
}}
}}
* {{medline-title
* {{medline-title
|title=Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts.
|title=Maintenance of membrane organization in the aging mouse brain as the determining factor for preventing receptor dysfunction and for improving response to anti-Alzheimer treatments.
|date=06.2019
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28347928
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553930
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.02.015
}}
==CNTNAP2==
 
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
* {{medline-title
|title=A common copy number variation polymorphism in the [[CNTNAP2]] gene: sexual dimorphism in association with healthy aging and disease.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25139204
|full-text-url=https://sci-hub.do/10.1159/000363320
}}
==COL2A1==
 
* {{medline-title
|title=Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis.
|date=08.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415892
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821202
}}
* {{medline-title
|title=Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritis chondrocytes.
|date=16.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28728848
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.07.094
}}
}}
==COPE==
==COPE==
Строка 805: Строка 1253:
|full-text-url=https://sci-hub.do/10.1017/S1041610217002319
|full-text-url=https://sci-hub.do/10.1017/S1041610217002319
}}
}}
==CPD==
==COQ7==


* {{medline-title
* {{medline-title
|title=Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease.
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|date=05.2019
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470706
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|full-text-url=https://sci-hub.do/10.1007/s00391-018-1377-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
}}
}}
* {{medline-title
* {{medline-title
|title=What Do Clinical Supervisors Require to Teach Residents in Family Medicine How to Care for Seniors?
|title=Gene expression differences in relation to age and social environment in queen and worker bumble bees.
|date=03.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29310735
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26883339
|full-text-url=https://sci-hub.do/10.1017/S0714980817000460
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.02.007
}}
}}
==CPE==
==COX5B==


* {{medline-title
* {{medline-title
|title=Cross-Sectional and Cumulative Longitudinal Central Nervous System Penetration Effectiveness Scores Are Not Associated With Neurocognitive Impairment in a Well Treated Aging Human Immunodeficiency Virus-Positive Population in Switzerland.
|title=Role of Mitochondrial Complex IV in Age-Dependent Obesity.
|date=07.2019
|date=13.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27626667
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612860
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2016.08.041
}}
}}
* {{medline-title
* {{medline-title
|title=COCOA (Theobroma cacao) Polyphenol-Rich Extract Increases the Chronological Lifespan of Saccharomyces cerevisiae.
|title=Loss of [[COX5B]] inhibits proliferation and promotes senescence via mitochondrial dysfunction in breast cancer.
|date=2016
|date=22.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29240368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26506233
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791237
}}
}}
==CPQ==
==CPQ==
Строка 847: Строка 1295:
|full-text-url=https://sci-hub.do/10.1007/s12640-019-00071-5
|full-text-url=https://sci-hub.do/10.1007/s12640-019-00071-5
}}
}}
==CRABP2==
==CPT1B==


* {{medline-title
* {{medline-title
|title=Preconception resveratrol intake against infertility: Friend or foe?
|title=Effects of carnitine palmitoyltransferases on cancer cellular senescence.
|date=04.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32273814
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30070697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138940
|full-text-url=https://sci-hub.do/10.1002/jcp.27042
}}
}}
* {{medline-title
* {{medline-title
|title=Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females.
|title=Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone.
|date=31.10.2017
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089527
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24760536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663855
|full-text-url=https://sci-hub.do/10.1530/EJE-14-0006
}}
}}
==CSRP1==
==CPT2==


* {{medline-title
* {{medline-title
|title=[[FOXO3]], a Molecular Search for the Fountain of Youth.
|title=The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats.
|date=07.03.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30849363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32729662
|full-text-url=https://sci-hub.do/10.1016/j.stem.2019.02.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511879
}}
}}
* {{medline-title
* {{medline-title
|title=[[FOXO3]]-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration.
|title=Glial β-oxidation regulates Drosophila energy metabolism.
|date=07.03.2019
|date=15.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661960
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25588812
|full-text-url=https://sci-hub.do/10.1016/j.stem.2018.12.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295106
}}
}}
==CTLA4==
==CR2==


* {{medline-title
* {{medline-title
|title=Horticultural Therapy Reduces Biomarkers of Immunosenescence and Inflammaging in Community-Dwelling Older Adults: A Feasibility Pilot Randomized Controlled Trial.
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|date=18.10.2020
|date=19.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33070170
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|full-text-url=https://sci-hub.do/10.1093/gerona/glaa271
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
}}
}}
* {{medline-title
* {{medline-title
|title=[Efficacy and toxicity of immune checkpoint inhibitors in elderly patients - 5th edition of the congress of pharmacology of anticancer drugs].
|title=Senescent dermal fibroblasts enhance stem cell migration through [[CCL2]]/C[[CR2]] axis.
|date=12.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30471959
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25808810
|full-text-url=https://sci-hub.do/10.1016/j.bulcan.2018.10.004
|full-text-url=https://sci-hub.do/10.1111/exd.12701
}}
}}
==CXCL11==
==CRABP2==


* {{medline-title
* {{medline-title
|title=Endothelial cells under therapy-induced senescence secrete [[CXCL11]], which increases aggressiveness of breast cancer cells.
|title=Preconception resveratrol intake against infertility: Friend or foe?
|date=10.10.2020
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659248
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32273814
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2020.06.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138940
}}
}}
* {{medline-title
* {{medline-title
|title=Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity.
|title=Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females.
|date=13.03.2019
|date=31.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30867067
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089527
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417215
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663855
}}
}}
==CXCL5==
==CREB5==


* {{medline-title
* {{medline-title
|title=Hassall's corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus.
|title=Cellular senescence induces replication stress with almost no affect on DNA replication timing.
|date=05.03.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534943
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963964
|full-text-url=https://sci-hub.do/10.1093/intimm/dxy073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133336
}}
}}
* {{medline-title
* {{medline-title
|title=Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age.
|title=Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90  study.
|date=09.2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891542
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26188803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105902
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506741
}}
}}
==CYLD==
==CREBBP==


* {{medline-title
* {{medline-title
|title=Premature aging and cancer development in transgenic mice lacking functional [[CYLD]].
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms.
|date=10.01.2019
|date=22.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30631004
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318
}}
}}
* {{medline-title
* {{medline-title
|title=Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis.
|title=Genetic variants in a 'cAMP element binding protein' (CREB)-dependent histone acetylation pathway influence memory performance in cognitively healthy elderly individuals.
|date=22.01.2019
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25150575
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.12.025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253058
}}
}}
==CYP1A1==
==CREM==


* {{medline-title
* {{medline-title
|title=Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population.
|title=Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells.
|date=10.2019
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31522824
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250567
|full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2019.08.010
|full-text-url=https://sci-hub.do/10.1111/andr.12665
}}
}}
* {{medline-title
* {{medline-title
|title=Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in [[CYP1A1]]-overexpressing breast cancer cells.
|title=Constitutive Expression of Inducible Cyclic Adenosine Monophosphate Early Repressor (ICER) in Cycling Quiescent Hematopoietic Cells: Implications for Aging Hematopoietic Stem Cells.
|date=15.12.2018
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27822872
|full-text-url=https://sci-hub.do/10.1016/j.bmc.2018.11.013
|full-text-url=https://sci-hub.do/10.1007/s12015-016-9701-5
}}
}}
==CYP1A2==
==CRYAB==


* {{medline-title
* {{medline-title
|title=Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of [[CYP1A2]]-Mediated Pharmacokinetics in Young and Elderly Chinese Adults.
|title=Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
|date=07.2019
|date=28.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767128
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389787
|full-text-url=https://sci-hub.do/10.1007/s40262-019-00737-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311499
}}
}}
* {{medline-title
* {{medline-title
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
|title=Quantitative proteomics analysis by iTRAQ in human nuclear cataracts of different ages and normal lens nuclei.
|date=12.2017
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25418515
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442
|full-text-url=https://sci-hub.do/10.1002/prca.201400061
}}
}}
==CYP27B1==
==CSRP1==


* {{medline-title
* {{medline-title
|title=Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance.
|title=[[FOXO3]], a Molecular Search for the Fountain of Youth.
|date=01.08.2018
|date=07.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955863
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30849363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693043
|full-text-url=https://sci-hub.do/10.1016/j.stem.2019.02.008
}}
}}
* {{medline-title
* {{medline-title
|title=Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism.
|title=[[FOXO3]]-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration.
|date=22.02.2018
|date=07.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661960
|full-text-url=https://sci-hub.do/10.1016/j.stem.2018.12.002
}}
==CTSL==
 
* {{medline-title
|title=Cathepsin L deficiency results in reactive oxygen species (ROS) accumulation and vascular cells activation.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29041825
|full-text-url=https://sci-hub.do/10.1080/10715762.2017.1393665
}}
* {{medline-title
|title=Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice.
|date=03.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388215
}}
==CYB5A==
 
* {{medline-title
|title=11-Oxygenated C19 Steroids Do Not Decline With Age in Women.
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753518
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525564
}}
* {{medline-title
|title=3βHSD and [[CYB5A]] double positive adrenocortical cells during adrenal development/aging.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24832628
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242803
}}
==CYP11B2==
 
* {{medline-title
|title=Expression of aldosterone synthase [[CYP11B2]] was inversely correlated with longevity.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30974191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786771
}}
* {{medline-title
|title=Age-Related Autonomous Aldosteronism.
|date=25.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28566337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568806
}}
==CYP24A1==
 
* {{medline-title
|title=Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism.
|date=22.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823
}}
}}
==CYP2D6==
* {{medline-title
|title=Environmental and genetic determinants of vitamin D status among older adults in London, UK.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26776442
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2016.01.005
}}
==CYP27A1==
 
* {{medline-title
|title=Prenatal betaine exposure alleviates corticosterone-induced inhibition of [[CYP27A1]] expression in the liver of juvenile chickens associated with its promoter DNA methylation.
|date=15.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039067
|full-text-url=https://sci-hub.do/10.1016/j.ygcen.2016.12.014
}}
* {{medline-title
|title=Synergic hypocholesterolaemic effect of n-3 PUFA and oestrogen by modulation of hepatic cholesterol metabolism in female rats.
|date=14.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26388416
|full-text-url=https://sci-hub.do/10.1017/S0007114515003517
}}
==CYP2A6==


* {{medline-title
* {{medline-title
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|title=Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits.
|date=05.2019
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396010
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
|full-text-url=https://sci-hub.do/10.1016/j.ijheh.2017.03.007
}}
}}
* {{medline-title
* {{medline-title
|title=[Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug].
|title=Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes.
|date=2018
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30175758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28153492
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00114
|full-text-url=https://sci-hub.do/10.1016/j.dmpk.2016.10.409
}}
}}
==CYP3A4==
==CYP2C8==


* {{medline-title
* {{medline-title
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|title=Paclitaxel-induced sensory peripheral neuropathy is associated with an [[ABCB1]] single nucleotide polymorphism and older age in Japanese.
|date=05.2019
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28447211
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
|full-text-url=https://sci-hub.do/10.1007/s00280-017-3314-9
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia.
|title=Determination of Human Hepatic [[CYP2C8]] and [[CYP1A2]] Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages.
|date=12.2017
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28228413
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442
|full-text-url=https://sci-hub.do/10.1124/dmd.116.074583
}}
}}
==CYP7A1==
==CYP3A7==


* {{medline-title
* {{medline-title
|title=Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats.
|title=Dynamics of Cytosine Methylation in the Proximal Promoters of [[CYP3A4]] and [[CYP3A7]] in Pediatric and Prenatal Livers.
|date=2019
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396457
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26772622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681801
|full-text-url=https://sci-hub.do/10.1124/dmd.115.068726
}}
}}
* {{medline-title
* {{medline-title
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio).
|title=Predicting the "First dose in children" of CYP3A-metabolized drugs: Evaluation of scaling approaches and insights into the [[CYP3A7]]-[[CYP3A4]] switch at young ages.
|date=03.2018
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24676942
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128
|full-text-url=https://sci-hub.do/10.1002/jcph.294
}}
}}
==DAO==
==DAO==
Строка 1032: Строка 1550:


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=04.07.2019
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
Строка 1043: Строка 1561:
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1312-5
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1312-5
}}
}}
==DDB1==
==DAXX==


* {{medline-title
* {{medline-title
|title=DCAF1 regulates Treg senescence via the ROS axis during immunological aging.
|title=[[ATRX]]-[[DAXX]] Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains.
|date=02.11.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32730228
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31361513
|full-text-url=https://sci-hub.do/10.1089/dna.2019.4752
}}
* {{medline-title
|title=Age-dependent differential expression of death-associated protein 6 (Daxx) in various peripheral tissues and different brain regions of C57BL/6 male mice.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27465500
|full-text-url=https://sci-hub.do/10.1007/s10522-016-9651-y
}}
==DBT==
 
* {{medline-title
|title=Diurnal rhythms of heart and respiratory rates in donkeys of different age groups during the cold-dry and hot-dry seasons in a tropical savannah.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187687
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125241
}}
* {{medline-title
|title=Anodal Transcranial Direct Current Stimulation Does Not Facilitate Dynamic Balance Task Learning in Healthy Old Adults.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28197085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281631
}}
==DCD==
 
* {{medline-title
|title=Improved metabolism and redox state with a novel preservation solution: implications for donor lungs after cardiac death ([[DCD]]).
|date=04-06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28597777
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467941
}}
* {{medline-title
|title=Functional connectivity of neural motor networks is disrupted in children with developmental coordination disorder and attention-deficit/hyperactivity disorder.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24818082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984446
}}
==DCTN3==
 
* {{medline-title
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
}}
* {{medline-title
|title=Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26954557
|full-text-url=https://sci-hub.do/10.1159/000443664
}}
==DDAH1==
 
* {{medline-title
|title=Dimethylarginine Dimethylaminohydrolase 1 Deficiency Induces the Epithelial to Mesenchymal Transition in Renal Proximal Tubular Epithelial Cells and Exacerbates Kidney Damage in Aged and Diabetic Mice.
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28594240
|full-text-url=https://sci-hub.do/10.1089/ars.2017.7022
}}
* {{medline-title
|title=Epigallocatechin-3-gallate ameliorates erectile function in aged rats via regulation of [[PRMT1]]/DDAH/ADMA/NOS metabolism pathway.
|date=05-06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27080477
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427783
}}
==DDAH2==
 
* {{medline-title
|title=Epigallocatechin-3-gallate ameliorates erectile function in aged rats via regulation of [[PRMT1]]/DDAH/ADMA/NOS metabolism pathway.
|date=05-06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27080477
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427783
}}
* {{medline-title
|title=Regulation of endothelial progenitor cell differentiation and function by dimethylarginine dimethylaminohydrolase 2 in an asymmetric dimethylarginine-independent manner.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24764313
|full-text-url=https://sci-hub.do/10.1002/cbin.10288
}}
==DDB1==
 
* {{medline-title
|title=DCAF1 regulates Treg senescence via the ROS axis during immunological aging.
|date=02.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32730228
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598062
}}
}}
Строка 1056: Строка 1658:
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907856
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907856
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003934
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003934
}}
==DDR2==
* {{medline-title
|title=Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833185
}}
* {{medline-title
|title=Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression.
|date=03.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27121132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041879
}}
}}
==DDX41==
==DDX41==
Строка 1070: Строка 1686:
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
}}
==DDX58==
* {{medline-title
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|date=14.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
}}
* {{medline-title
|title=Age-associated mRNA expression changes in bovine endometrial cells in vitro.
|date=14.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28806906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556672
}}
}}
==DEGS1==
==DEGS1==
Строка 1099: Строка 1701:
|full-text-url=https://sci-hub.do/10.1016/j.jsams.2017.08.022
|full-text-url=https://sci-hub.do/10.1016/j.jsams.2017.08.022
}}
}}
==DICER1==
==DGCR8==


* {{medline-title
* {{medline-title
|title=[[DICER1]]: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging.
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif.
|date=2018
|date=29.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087677
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066587
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004
}}
* {{medline-title
|title=miRNAs 182 and 183 are necessary to maintain adult cone photoreceptor outer segments and visual function.
|date=06.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25002228
|full-text-url=https://sci-hub.do/10.1016/j.neuron.2014.06.020
}}
==DHX9==
 
* {{medline-title
|title=The biology of [[DHX9]] and its potential as a therapeutic target.
|date=05.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27034008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173168
}}
* {{medline-title
|title=Suppression of the [[DHX9]] helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.
|date=15.08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24990949
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132785
}}
}}
==DIAPH1==
* {{medline-title
* {{medline-title
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability.
|title=Diaphanous 1 ([[DIAPH1]]) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease.
|date=06.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966194
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082178
}}
* {{medline-title
|title=The multiple faces of RAGE--opportunities for therapeutic intervention in aging and chronic disease.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26558318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941230
}}
}}
==DISC1==
==DIRAS3==


* {{medline-title
* {{medline-title
|title=Age-Related Changes in Topological Degradation of White Matter Networks and Gene Expression in Chronic Schizophrenia.
|title=Silencing of the small GTPase [[DIRAS3]] induces cellular senescence in human white adipose stromal/progenitor cells.
|date=11.2017
|date=17.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28946750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28316325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695754
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391236
}}
}}
* {{medline-title
* {{medline-title
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|title=Weight Loss Upregulates the Small GTPase [[DIRAS3]] in Human White Adipose Progenitor Cells, Which Negatively Regulates Adipogenesis and Activates Autophagy via Akt-mTOR Inhibition.
|date=19.09.2017
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27211557
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856797
}}
}}
==DKC1==
==DKK2==


* {{medline-title
* {{medline-title
|title=Successful liver transplantation in short telomere syndromes without bone marrow failure due to [[DKC1]] mutation.
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women.
|date=05.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32166868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588
|full-text-url=https://sci-hub.do/10.1111/petr.13695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448
}}
}}
* {{medline-title
* {{medline-title
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=04.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
}}
==DLX5==
==DLX5==
Строка 1155: Строка 1785:
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011
}}
}}
==DRD3==
==DNAJC5==


* {{medline-title
* {{medline-title
|title=Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality.
|title=Gene Therapy of Adult Neuronal Ceroid Lipofuscinoses with CRISPR/Cas9 in Zebrafish.
|date=02.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30439596
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28478735
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.10.012
|full-text-url=https://sci-hub.do/10.1089/hum.2016.190
}}
}}
* {{medline-title
* {{medline-title
|title=Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.
|title=Caenorhabditis elegans dnj-14, the orthologue of the [[DNAJC5]] gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol.
|date=07.2018
|date=15.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29637543
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24947438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105503
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204773
}}
}}
==DSP==
==DOCK11==


* {{medline-title
* {{medline-title
|title=Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions.
|title=[Immunosenescence: The Forefront of Infection and Trophic Control].
|date=10.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115558
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754798
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00193-3
}}
}}
* {{medline-title
* {{medline-title
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease.
|title=Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle.
|date=05.2018
|date=29.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171
|full-text-url=https://sci-hub.do/10.4238/gmr16029091
}}
}}
==DST==
==DOT1L==


* {{medline-title
* {{medline-title
|title=Ancestral germen/soma distinction in microbes: Expanding the disposable soma theory of aging to all unicellular lineages.
|title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction.
|date=07.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268207
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101064
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018
}}
}}
* {{medline-title
* {{medline-title
|title=Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study.
|title=NF-κB activation impairs somatic cell reprogramming in ageing.
|date=10.2019
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386173
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26214134
|full-text-url=https://sci-hub.do/10.1111/jgs.16089
|full-text-url=https://sci-hub.do/10.1038/ncb3207
}}
}}
==E2F2==
==DRAM1==


* {{medline-title
* {{medline-title
|title=MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment.
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
|date=08.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896785
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052401
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896
}}
}}
* {{medline-title
* {{medline-title
|title=In situ regeneration of retinal pigment epithelium by gene transfer of [[E2F2]]: a potential strategy for treatment of macular degenerations.
|title=Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium.
|date=12.2017
|date=27.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29188796
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26468292
|full-text-url=https://sci-hub.do/10.1038/gt.2017.89
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661415
}}
}}
==EDARADD==
==DRD4==


* {{medline-title
* {{medline-title
|title=Age prediction in living: Forensic epigenetic age estimation based on blood samples.
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children.
|date=11.2020
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721866
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915
|full-text-url=https://sci-hub.do/10.1016/j.legalmed.2020.101763
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird.
|title=Age-dependent role of pre- and perinatal factors in interaction with genes on ADHD symptoms across adolescence.
|date=2017
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28259004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2017.02.014
}}
}}
==EN1==
==DROSHA==


* {{medline-title
* {{medline-title
|title=Electrochemically detecting DNA methylation in the [[EN1]] gene promoter: implications for understanding ageing and disease.
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability.
|date=27.11.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33135722
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072
}}
}}
* {{medline-title
* {{medline-title
|title=The role of DNA methylation in ageing and cancer.
|title=Centenarians maintain miRNA biogenesis pathway while it is impaired in octogenarians.
|date=11.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29708096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28754532
|full-text-url=https://sci-hub.do/10.1017/S0029665118000150
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.07.003
}}
}}
==ERBB2==
==DSCAM==


* {{medline-title
* {{medline-title
|title=The biological age linked to oxidative stress modifies breast cancer aggressiveness.
|title=Age- and speed-dependent modulation of gaits in [[DSCAM]]  mutant mice.
|date=20.05.2018
|date=01.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29550329
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29093169
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.03.012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867377
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of human age-associated gene co-expressions in functional modules using liquid association.
|title=Developmentally dynamic colocalization patterns of [[DSCAM]] with adhesion and synaptic proteins in the mouse retina.
|date=02.01.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416677
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25352748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191645
}}
}}
==ETS1==
==DSE==


* {{medline-title
* {{medline-title
|title=The transcription factor [[ETS1]] promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1.
|title=Impact of Intensive Lifestyle Intervention on Disability-Free Life Expectancy: The Look AHEAD Study.
|date=06.12.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31659122
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545462
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901313
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911793
}}
}}
* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Changes in regional body composition over 8 years in a randomized lifestyle trial: The look AHEAD study.
|date=15.11.2017
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27465756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134917
}}
}}
==F7==
==DUSP16==


* {{medline-title
* {{medline-title
|title=The Pattern of Mu Rhythm Modulation During Emotional Destination Memory: Comparison Between Mild Cognitive Impairment Patients and Healthy Controls.
|title=Nicotinamide Mononucleotide, an NAD  Precursor, Rescues Age-Associated Susceptibility to AKI in a Sirtuin 1-Dependent Manner.
|date=2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524160
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28246130
|full-text-url=https://sci-hub.do/10.3233/JAD-190311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533221
}}
}}
* {{medline-title
* {{medline-title
|title=High levels of incidental physical activity are positively associated with cognition and EEG activity in aging.
|title=[[DUSP16]] ablation arrests the cell cycle and induces cellular senescence.
|date=2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29370215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26381291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784952
|full-text-url=https://sci-hub.do/10.1111/febs.13518
}}
}}
==FAAH==
==E2F2==


* {{medline-title
* {{medline-title
|title=Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice.
|title=MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment.
|date=02.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32095523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896785
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015690
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052401
}}
}}
* {{medline-title
* {{medline-title
|title=Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan.
|title=In situ regeneration of retinal pigment epithelium by gene transfer of [[E2F2]]: a potential strategy for treatment of macular degenerations.
|date=05.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29188796
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548519
|full-text-url=https://sci-hub.do/10.1038/gt.2017.89
}}
}}
==FABP4==
==EBF1==


* {{medline-title
* {{medline-title
|title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation.
|title=Genome-wide Association Study of Parental Life Span.
|date=05.2018
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27816938
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861941
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial [[APLNR]] regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.
|title=Non-Lethal Ionizing Radiation Promotes Aging-Like Phenotypic Changes of Human Hematopoietic Stem and Progenitor Cells in Humanized Mice.
|date=13.09.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26161905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498777
}}
}}
==FANCD2==
==ECM1==


* {{medline-title
* {{medline-title
|title=TFG-maintaining stability of overlooked [[FANCD2]] confers early DNA-damage response.
|title=Novel role of extracellular matrix protein 1 ([[ECM1]]) in cardiac aging and myocardial infarction.
|date=24.10.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099537
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655164
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383988
}}
}}
* {{medline-title
* {{medline-title
|title=[[FANCD2]] and DNA Damage.
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=19.08.2017
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825622
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
==FGFR4==
==EDARADD==


* {{medline-title
* {{medline-title
|title=[[FGFR4]] Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer.
|title=Age prediction in living: Forensic epigenetic age estimation based on blood samples.
|date=14.10.2020
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066597
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602396
|full-text-url=https://sci-hub.do/10.1016/j.legalmed.2020.101763
}}
}}
* {{medline-title
* {{medline-title
|title=The Klotho proteins in health and disease.
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird.
|date=01.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256
|full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723
}}
}}
==FHL2==
==EIF2B1==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=10.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation of the [[ELOVL2]], [[FHL2]], [[KLF14]], C1orf132/MIR29B2C, and [[TRIM59]] genes for age prediction from blood, saliva, and buccal swab samples.
|title=Infantile onset Vanishing White Matter disease associated with a novel [[EIF2B5]] variant, remarkably long life span, severe epilepsy, and hypopituitarism.
|date=01.2019
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30300865
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25758335
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.36961
}}
}}
==FLT1==
==EIF2B5==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=15.11.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|title=Infantile onset Vanishing White Matter disease associated with a novel [[EIF2B5]] variant, remarkably long life span, severe epilepsy, and hypopituitarism.
|date=08.10.2018
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25758335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.36961
}}
}}
==FN1==
==EMB==


* {{medline-title
* {{medline-title
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms.
|title=X[[RCC1]] and XPD genetic polymorphisms and susceptibility to age-related cataract: a meta-analysis.
|date=22.07.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384174
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Fibronectin 1 on Cell Proliferation, Senescence and Apoptosis of Human Glioma Cells Through the PI3K/AKT Signaling Pathway.
|title=Diabetes self-management programmes in older adults: a systematic review and meta-analysis.
|date=2018
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25865179
|full-text-url=https://sci-hub.do/10.1159/000492096
|full-text-url=https://sci-hub.do/10.1111/dme.12780
}}
}}
==FOXA1==
==EMD==


* {{medline-title
* {{medline-title
|title=Analyses of an epigenetic switch involved in the activation of pioneer factor [[FOXA1]] leading to the prognostic value of estrogen receptor and [[FOXA1]] co-expression in breast cancer.
|title=Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence.
|date=28.09.2019
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562808
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27268410
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986421
}}
}}
* {{medline-title
* {{medline-title
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
|title=Electromechanical delay of the knee extensor muscles: comparison among young, middle-age and older individuals.
|date=05.06.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24797398
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
|full-text-url=https://sci-hub.do/10.1111/cpf.12157
}}
}}
==FOXF1==
==EN1==


* {{medline-title
* {{medline-title
|title=Functional CRISPR screen identifies AP1-associated enhancer regulating [[FOXF1]] to modulate oncogene-induced senescence.
|title=Electrochemically detecting DNA methylation in the [[EN1]] gene promoter: implications for understanding ageing and disease.
|date=17.08.2018
|date=27.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119690
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33135722
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670582
}}
}}
* {{medline-title
* {{medline-title
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|title=The role of DNA methylation in ageing and cancer.
|date=26.06.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29708096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
|full-text-url=https://sci-hub.do/10.1017/S0029665118000150
}}
}}
==FOXP3==
==ENC1==


* {{medline-title
* {{medline-title
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
}}
* {{medline-title
* {{medline-title
|title=Enhanced expression of PD-1 and other activation markers by CD4+ T cells of young but not old patients with metastatic melanoma.
|title=Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
|date=06.2018
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546435
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28441426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951899
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404753
}}
}}
==FSTL3==
==ENO1==


* {{medline-title
* {{medline-title
|title=Activin type II receptor signaling in cardiac aging and heart failure.
|title=Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells.
|date=06.03.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842316
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32355541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191177
}}
}}
* {{medline-title
* {{medline-title
|title=Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise.
|title=Targeting the Warburg effect in cancer cells through [[ENO1]] knockdown rescues oxidative phosphorylation and induces growth arrest.
|date=01.10.2018
|date=02.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30085147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26734996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179167
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868708
}}
}}
==FUNDC1==
==ENTPD7==


* {{medline-title
* {{medline-title
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence.
|title=Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 ([[ENTPD7]]).
|date=15.03.2019
|date=23.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31443651
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708200
}}
}}
* {{medline-title
* {{medline-title
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.
|title=SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.
|date=01.02.2019
|date=01.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27737960
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088567
}}
}}
==GALT==
==EPHA2==


* {{medline-title
* {{medline-title
|title=Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life.
|title=Germ-line and somatic [[EPHA2]] coding variants in lens aging and cataract.
|date=03.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30523311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29267365
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739433
}}
}}
* {{medline-title
* {{medline-title
|title=Dietary Animal Plasma Proteins Improve the Intestinal Immune Response in Senescent Mice.
|title=[[EPHA2]] Polymorphisms in Estonian Patients with Age-Related Cataract.
|date=11.12.2017
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29232896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24673449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748796
|full-text-url=https://sci-hub.do/10.3109/13816810.2014.902080
}}
}}
==GAS6==
==EPM2A==


* {{medline-title
* {{medline-title
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|title=Inflammation in Lafora Disease: Evolution with Disease Progression in Laforin and Malin Knock-out Mouse Models.
|date=2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27041370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472678
}}
}}
* {{medline-title
* {{medline-title
|title=Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
|title=Loss of GABAergic cortical neurons underlies the neuropathology of Lafora disease.
|date=2017
|date=28.01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28957414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24472629
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917365
}}
}}
==GATA2==
==ERBB2==


* {{medline-title
* {{medline-title
|title=[[GATA2]] hypomorphism induces chronic myelomonocytic leukemia in mice.
|title=The biological age linked to oxidative stress modifies breast cancer aggressiveness.
|date=04.2019
|date=20.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29550329
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447832
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.03.012
}}
}}
* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=Identification of human age-associated gene co-expressions in functional modules using liquid association.
|date=2017
|date=02.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416677
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787419
}}
}}
==GATA3==
==ERCC2==


* {{medline-title
* {{medline-title
|title=An imbalance in the T-helper phenotypes displayed by senescent [[CD4]] [[CD28]]  T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus.
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=11.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111238
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://sci-hub.do/10.1177/0961203318793715
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland.
|title=X[[RCC1]] and XPD genetic polymorphisms and susceptibility to age-related cataract: a meta-analysis.
|date=12.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30004288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262508
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384174
}}
}}
==GDF3==
==EWSR1==


* {{medline-title
* {{medline-title
|title=In vivo [[GDF3]] administration abrogates aging related muscle regeneration delay following acute sterile injury.
|title=[[EWSR1]], a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways.
|date=10.2018
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003692
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30481590
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156497
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527469
}}
}}
* {{medline-title
* {{medline-title
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.
|title=[[EWSR1]]/ELF5 induces acute myeloid leukemia by inhibiting p53/p21 pathway.
|date=05.10.2017
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27627705
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198945
}}
}}
==GIT2==
==EXO1==


* {{medline-title
* {{medline-title
|title=Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic [[GIT2]] in aging trajectories.
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|date=12.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31574270
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111150
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
}}
}}
* {{medline-title
* {{medline-title
|title=[[GIT2]]-A keystone in ageing and age-related disease.
|title=Exonuclease 1 and its versatile roles in DNA repair.
|date=05.2018
|date=11-12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27494243
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002
|full-text-url=https://sci-hub.do/10.1080/10409238.2016.1215407
}}
}}
==GK==
==FAHD1==


* {{medline-title
* {{medline-title
|title=Progression of diabetic kidney disease in T2DN rats.
|title=Oxaloacetate decarboxylase [[FAH]]D1 - a new regulator of mitochondrial function and senescence.
|date=01.12.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055189
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960784
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.07.007
}}
}}
* {{medline-title
* {{medline-title
|title=Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging.
|title=Depletion of oxaloacetate decarboxylase [[FAH]]D1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells.
|date=04.2019
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30609251
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286170
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413652
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.03.004
}}
}}
==GLS==
==FANCD2==


* {{medline-title
* {{medline-title
|title=Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography.
|title=TFG-maintaining stability of overlooked [[FANCD2]] confers early DNA-damage response.
|date=15.07.2018
|date=24.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29784576
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099537
|full-text-url=https://sci-hub.do/10.1016/j.amjcard.2018.03.355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655164
}}
}}
* {{medline-title
* {{medline-title
|title=Future Perspectives for Management of Stage A Heart Failure.
|title=[[FANCD2]] and DNA Damage.
|date=01.07.2018
|date=19.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731506
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055033
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578191
}}
}}
==GNG3==
==FASN==


* {{medline-title
* {{medline-title
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.
|date=07.2018
|date=01.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25302649
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://sci-hub.do/10.1002/ijc.29261
}}
}}
==GNRH1==
==FBN1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=15.11.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
* {{medline-title
* {{medline-title
|title=Elucidating the genetic architecture of reproductive ageing in the Japanese population.
|title=Muscle and Bone Impairment in Children With Marfan Syndrome: Correlation With Age and [[FBN1]] Genotype.
|date=17.05.2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29773799
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25656438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958096
|full-text-url=https://sci-hub.do/10.1002/jbmr.2471
}}
}}
==GPR39==
==FBN2==


* {{medline-title
* {{medline-title
|title=Zinc-mediated Neurotransmission in Alzheimer's Disease: A Potential Role of the [[GPR39]] in Dementia.
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging.
|date=2020
|date=26.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31272355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327932
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848
}}
}}
* {{medline-title
* {{medline-title
|title=[[GPR39]] agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence.
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=12.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237151
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1626405
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
==GPT==
==FBXO31==


* {{medline-title
* {{medline-title
|title=Brain Structural-Behavioral Correlates Underlying Grooved Pegboard Test Performance Across Lifespan.
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|date=07.07.2020
|date=19.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32631206
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|full-text-url=https://sci-hub.do/10.1080/00222895.2020.1787320
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults.
|title=Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis.
|date=2019
|date=19.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31275139
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26056366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581027
}}
}}
==GRIK2==
==FEN1==


* {{medline-title
* {{medline-title
|title=Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2.
|title=The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and [[FEN1]]-Mediated Flap Cleavage during Polymerase δ Elongation.
|date=11-12.2020
|date=01.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099472
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27849570
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247617
}}
}}
* {{medline-title
* {{medline-title
|title=Isoforms of Ionotropic Glutamate Receptor [[GRIK2]] Induce Senescence of Carcinoma Cells.
|title=[[RECQL5]] has unique strand annealing properties relative to the other human RecQ helicase proteins.
|date=01-02.2019
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30587499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26717024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903426
}}
}}
==GRK5==
==FGF6==


* {{medline-title
* {{medline-title
|title=Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone.
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|date=01.05.2019
|date=06.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31043680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494869
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
}}
}}
* {{medline-title
* {{medline-title
|title=[[GRK5]] - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders.
|title=Regulation of skeletal muscle stem cells by fibroblast growth factors.
|date=2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30618771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28249356
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304357
|full-text-url=https://sci-hub.do/10.1002/dvdy.24495
}}
}}
==GRSF1==
==FGFR2==


* {{medline-title
* {{medline-title
|title=[[GRSF1]] is an age-related regulator of senescence.
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|date=03.04.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447602
|full-text-url=https://sci-hub.do/10.1002/path.5314
}}
}}
* {{medline-title
* {{medline-title
|title=[[GRSF1]] suppresses cell senescence.
|title=Inducible Activation of [[FGFR2]] in Adult Mice Promotes Bone Formation After Bone Marrow Ablation.
|date=07.08.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30086537
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28650109
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128438
|full-text-url=https://sci-hub.do/10.1002/jbmr.3204
}}
}}
==GSTA4==
==FGFR4==


* {{medline-title
* {{medline-title
|title=Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue.
|title=[[FGFR4]] Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer.
|date=02.2019
|date=14.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066597
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602396
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=The Klotho proteins in health and disease.
|date=12.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3
}}
}}
==HAL==
==FHL1==


* {{medline-title
* {{medline-title
|title=Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population.
|title=The forkhead-like transcription factor (Fhl1p) maintains yeast replicative lifespan by regulating ribonucleotide reductase 1 (RNR1) gene transcription.
|date=06-09.2018
|date=17.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31066639
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28495531
|full-text-url=https://sci-hub.do/10.1080/15360288.2018.1513434
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.05.038
}}
}}
* {{medline-title
* {{medline-title
|title=Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats.
|title=Transcription factor genes essential for cell proliferation and replicative lifespan in budding yeast.
|date=06.2019
|date=31.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31049689
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26022127
|full-text-url=https://sci-hub.do/10.1007/s00540-019-02646-0
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.05.067
}}
}}
==HAPLN1==
==FLT1==


* {{medline-title
* {{medline-title
|title=Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=01.2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279173
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328333
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Changes in [[HAPLN1]] Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis.
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|date=01.2019
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279172
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328344
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
}}
}}
==HAS1==
==FN1==


* {{medline-title
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms.
|date=20.06.2019
|date=22.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts.
|title=Effects of Fibronectin 1 on Cell Proliferation, Senescence and Apoptosis of Human Glioma Cells Through the PI3K/AKT Signaling Pathway.
|date=01.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048971
|full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7
|full-text-url=https://sci-hub.do/10.1159/000492096
}}
}}
==HBP1==
==FOXA2==


* {{medline-title
* {{medline-title
|title=Suppression of p38/[[HBP1]] pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence.
|title=Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts.
|date=03-04.2020
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32549582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635509
|full-text-url=https://sci-hub.do/10.23812/20-63-A-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576272
}}
}}
* {{medline-title
* {{medline-title
|title=Transcription factor [[HBP1]]: A regulator of senescence and apoptosis of preadipocytes.
|title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.
|date=17.09.2019
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331641
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.07.048
|full-text-url=https://sci-hub.do/10.1134/S0006297915030062
}}
}}
==HCN1==
==FOXC1==


* {{medline-title
* {{medline-title
|title=Protein expression changes of [[HCN1]] and HCN2 in hippocampal subregions of gerbils during the normal aging process.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=11.2019
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32128096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038419
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
* {{medline-title
* {{medline-title
|title=HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation.
|title=[[FOXC1]] maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential.
|date=15.02.2019
|date=15.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30124776
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801248
}}
}}
==HGD==
==FOXF1==


* {{medline-title
* {{medline-title
|title=High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans.
|title=Functional CRISPR screen identifies AP1-associated enhancer regulating [[FOXF1]] to modulate oncogene-induced senescence.
|date=2019
|date=17.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31846489
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119690
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097335
}}
}}
* {{medline-title
* {{medline-title
|title=A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of [i]C. elegans[/i].
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|date=05.10.2018
|date=26.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
}}
}}
==HLA-A==
==FOXL2==


* {{medline-title
* {{medline-title
|title=Reduced expression of the lncRNA NRON is a potential hallmark of the CMV-amplified CD8+ T cell accumulations commonly seen in older humans.
|title=Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor.
|date=01.2019
|date=09.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415066
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29523193
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845161
}}
}}
* {{medline-title
* {{medline-title
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|title=Different therapeutic effects of cells derived from human amniotic membrane on premature ovarian aging depend on distinct cellular biological characteristics.
|date=2017
|date=27.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28750654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530953
}}
}}
==HLA-B==
==FSHB==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.
|date=10.2019
|date=29.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598835
}}
}}
* {{medline-title
* {{medline-title
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|title='Carriers of variant luteinizing hormone (V-LH) among 1593 Baltic men have significantly higher serum LH'.
|date=2017
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25820123
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832392
}}
}}
==HLA-C==
==FSTL3==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Activin type II receptor signaling in cardiac aging and heart failure.
|date=10.2019
|date=06.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124007
}}
}}
* {{medline-title
* {{medline-title
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|title=Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise.
|date=2017
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30085147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179167
}}
}}
==HLA-DPB1==
==FXN==


* {{medline-title
* {{medline-title
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|title=Two different pathogenic mechanisms, dying-back axonal neuropathy and pancreatic senescence, are present in the YG8R mouse model of Friedreich's ataxia.
|date=09.2019
|date=01.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27079523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920149
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Mitochondrial dysfunction induced by frataxin deficiency is associated with cellular senescence and abnormal calcium metabolism.
|date=10.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24860428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026758
}}
}}
==HMOX1==
==GAS6==


* {{medline-title
* {{medline-title
|title=Well-aging: A new strategy for skin homeostasis under multi-stressed conditions.
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|date=02.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31232507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|title=Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
|date=08.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28957414
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619771
}}
}}
==HRAS==
==GATA2==


* {{medline-title
* {{medline-title
|title=How do combinations of unhealthy behaviors relate to attitudinal factors and subjective health among the adult population in the Netherlands?
|title=[[GATA2]] hypomorphism induces chronic myelomonocytic leukemia in mice.
|date=03.04.2020
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32245376
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447832
}}
}}
* {{medline-title
* {{medline-title
|title=Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype.
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|date=07.02.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31940439
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032038
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
}}
}}
==HSF2==
==GCAT==


* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis.
|date=15.04.2019
|date=03.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29551589
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2018.02.004
}}
}}
* {{medline-title
* {{medline-title
|title=Nutrition and water temperature regulate the expression of heat-shock proteins in golden pompano larvae (Trachinotus ovata, Limmaeus 1758).
|title=Epigenetic regulation of the nuclear-coded [[GCAT]] and [[SHMT2]] genes confers human age-associated mitochondrial respiration defects.
|date=04.2019
|date=22.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30397841
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26000717
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0578-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377050
}}
}}
==HSPA1A==
==GCKR==


* {{medline-title
* {{medline-title
|title=Vitamin D3 treatment regulates apoptosis, antioxidant defense system, and DNA integrity in the epididymal sperm of an aged rat model.
|title=The [[ADAMTS9]] gene is associated with cognitive aging in the elderly in a Taiwanese population.
|date=12.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566824
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28225792
|full-text-url=https://sci-hub.do/10.1002/mrd.23280
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321460
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells.
|title=Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.
|date=01.09.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329260
|full-text-url=https://sci-hub.do/10.1556/2060.105.2018.3.20
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013013
}}
}}
==ID1==
==GDF3==


* {{medline-title
* {{medline-title
|title=Commentary on Some Recent Theses Relevant to Combating Aging: April 2019.
|title=In vivo [[GDF3]] administration abrogates aging related muscle regeneration delay following acute sterile injury.
|date=04.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30957657
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003692
|full-text-url=https://sci-hub.do/10.1089/rej.2019.2201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156497
}}
}}
* {{medline-title
* {{medline-title
|title=ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.
|date=12.09.2017
|date=05.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847931
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603998
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149
}}
}}
==ID3==
==GDF9==


* {{medline-title
* {{medline-title
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|date=08.2019
|date=18.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells.
|date=02.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://sci-hub.do/10.1071/RD14472
}}
}}
==IDE==
==GIT1==


* {{medline-title
* {{medline-title
|title=Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
|title=[[GIT2]]-A keystone in ageing and age-related disease.
|date=2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32538851
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267
|full-text-url=https://sci-hub.do/10.3233/JAD-200308
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002
}}
}}
* {{medline-title
* {{medline-title
|title=Hyperinsulinemia is associated with increasing insulin secretion but not with decreasing insulin clearance in an age-related metabolic dysfunction mice model.
|title=GluN3A promotes dendritic spine pruning and destabilization during postnatal development.
|date=06.2019
|date=09.07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30370604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25009255
|full-text-url=https://sci-hub.do/10.1002/jcp.27667
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608362
}}
}}
==IDS==
==GLB1==


* {{medline-title
* {{medline-title
|title=Effect of immediate dentine sealing on the aging and fracture strength of lithium disilicate inlays and overlays.
|title=Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence.
|date=10.2020
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32957211
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802937
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2020.103906
|full-text-url=https://sci-hub.do/10.1016/j.plefa.2015.10.006
}}
}}
* {{medline-title
* {{medline-title
|title=Increased double limb support times during walking in right limb dominant healthy older adults with low bone density.
|title=Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis.
|date=06.2018
|date=02.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730490
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391655
|full-text-url=https://sci-hub.do/10.1016/j.gaitpost.2018.04.036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824610
}}
}}
==IGFBP1==
==GLI1==


* {{medline-title
* {{medline-title
|title=Role of [[IGFBP1]] in the senescence of vascular endothelial cells and severity of aging‑related coronary atherosclerosis.
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|date=11.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777673
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
}}
}}
* {{medline-title
* {{medline-title
|title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age.
|title=[[GLI1]]  progenitor cells in the adrenal capsule of the adult mouse give rise to heterotopic gonadal-like tissue.
|date=04.2018
|date=05.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27585489
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235954
}}
}}
==IL1A==
==GLRX==


* {{medline-title
* {{medline-title
|title=IL1B triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via CCL2.
|title=Gender- and region-dependent changes of redox biomarkers in the brain of successfully aging LOU/C rats.
|date=25.10.2020
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099841
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25956602
|full-text-url=https://sci-hub.do/10.1111/aji.13365
|full-text-url=https://sci-hub.do/10.1016/j.mad.2015.04.002
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated mRNA expression changes in bovine endometrial cells in vitro.
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
|date=14.08.2017
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28806906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556672
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201
}}
}}
==IL7==
==GNB3==


* {{medline-title
* {{medline-title
|title=[[SCAMP4]] enhances the senescent cell secretome.
|title=Ablation of [[EYS]] in zebrafish causes mislocalisation of outer segment proteins, F-actin disruption and cone-rod dystrophy.
|date=01.07.2018
|date=05.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967290
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28378834
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380955
}}
}}
* {{medline-title
* {{medline-title
|title=Thymic Atrophy: Experimental Studies and Therapeutic Interventions.
|title=[[GNB3]], eNOS, and mitochondrial DNA polymorphisms correlate to natural longevity in a Xinjiang Uygur population.
|date=01.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28960415
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24376503
|full-text-url=https://sci-hub.do/10.1111/sji.12618
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869651
}}
}}
==INSL3==
==GNG3==


* {{medline-title
* {{medline-title
|title=Effect of Thyroxine Replacement on Leydig Cell and Sertoli Cell Function in Men with Hypothyroidism.
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|date=05-06.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33083267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
}}
}}
* {{medline-title
* {{medline-title
|title=Age related and seasonal changes of plasma concentrations of insulin-like peptide 3 and testosterone from birth to early-puberty in Thoroughbred male horses.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=01.07.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31029851
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2019.04.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==IQGAP1==
==GNRH1==


* {{medline-title
* {{medline-title
|title=[[IQGAP1]]-dysfunction leads to induction of senescence in human vascular smooth muscle cells.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=09.2020
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592713
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111295
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
* {{medline-title
* {{medline-title
|title=Hyaluronan-binding protein 1 (HABP1) overexpression triggers induction of senescence in fibroblasts cells.
|title=Elucidating the genetic architecture of reproductive ageing in the Japanese population.
|date=06.2020
|date=17.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32068317
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29773799
|full-text-url=https://sci-hub.do/10.1002/cbin.11326
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958096
}}
}}
==IRF4==
==GP6==


* {{medline-title
* {{medline-title
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=08.2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice.
|title=Estimation of human age using N-glycan profiles from bloodstains.
|date=11.2017
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28905935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25787342
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550657
}}
}}
==IRF7==
==GPER1==


* {{medline-title
* {{medline-title
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|title=30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Nongenomic effects via the mineralocorticoid receptor.
|date=14.01.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28348113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
|full-text-url=https://sci-hub.do/10.1530/JOE-16-0659
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|title=Diverse Synaptic Distributions of G Protein-coupled Estrogen Receptor 1 in Monkey Prefrontal Cortex with Aging and Menopause.
|date=06.2018
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26941383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909633
}}
}}
==KIT==
==GPR17==


* {{medline-title
* {{medline-title
|title=Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-[[KIT]].
|title=Pharmaceutical Rejuvenation of Age-Associated Decline in Spatial Memory.
|date=04.2020
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223330
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27881050
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221484
|full-text-url=https://sci-hub.do/10.1089/rej.2016.1903
}}
}}
* {{medline-title
* {{medline-title
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
|title=Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.
|date=06.2018
|date=27.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26506265
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639806
}}
}}
==L1CAM==
==GPR3==


* {{medline-title
* {{medline-title
|title=Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression.
|title=Mice lacking [[GPR3]] receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue.
|date=12.09.2019
|date=12.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31510944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26455425
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601089
}}
}}
* {{medline-title
* {{medline-title
|title=Induction, regulation and roles of neural adhesion molecule [[L1CAM]] in cellular senescence.
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells.
|date=28.03.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615539
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892697
|full-text-url=https://sci-hub.do/10.1071/RD14472
}}
}}
==LAMP2==
==GPR39==


* {{medline-title
* {{medline-title
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|title=Zinc-mediated Neurotransmission in Alzheimer's Disease: A Potential Role of the [[GPR39]] in Dementia.
|date=07.12.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31272355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327932
}}
}}
* {{medline-title
* {{medline-title
|title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers.
|title=[[GPR39]] agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence.
|date=02.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237151
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1626405
}}
}}
==LAT2==
==GPR55==


* {{medline-title
* {{medline-title
|title=Blood glucose, amino acid profiles and nutrient transporter gene expressions in the small intestine of low and normal birthweight piglets during the early suckling period.
|title=Age-dependent plasticity in endocannabinoid modulation of pain processing through postnatal development.
|date=05.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971346
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767505
|full-text-url=https://sci-hub.do/10.1016/j.tvjl.2019.02.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642337
}}
}}
* {{medline-title
* {{medline-title
|title=Skeletal muscle: from birth to old age, routes to mechanical and metabolic failure.
|title=[[GPR55]] deletion in mice leads to age-related ventricular dysfunction and impaired adrenoceptor-mediated inotropic responses.
|date=2017
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29099099
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25275556
|full-text-url=https://sci-hub.do/10.24875/GMM.17000008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183508
}}
}}
==LATS2==
==GRB10==


* {{medline-title
* {{medline-title
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|title=De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver.
|date=25.06.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555819
 
|full-text-url=https://sci-hub.do/10.1530/JME-18-0018
}}
}}
* {{medline-title
* {{medline-title
|title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis.
|title=Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis.
|date=03.2019
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824446
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607
|full-text-url=https://sci-hub.do/10.1136/bjsports-2014-094073
}}
}}
==LCT==
==GRB2==


* {{medline-title
* {{medline-title
|title=Functional MRI of Letter Cancellation Task Performance in Older Adults.
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice.
|date=2019
|date=21.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31057377
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477506
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397
}}
}}
* {{medline-title
* {{medline-title
|title=Milk Intake at Midlife and Cognitive Decline over 20 Years. The Atherosclerosis Risk in Communities (ARIC) Study.
|title=The different expression profiles of microRNAs in elderly and young human dental pulp and the role of miR-433 in human dental pulp cells.
|date=17.10.2017
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039795
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25778413
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691750
|full-text-url=https://sci-hub.do/10.1016/j.mad.2015.03.001
}}
}}
==LDHA==
==GRIA2==


* {{medline-title
* {{medline-title
|title=Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16  inactivation.
|title=The EpiTect Methyl qPCR Assay as novel age estimation method in forensic biology.
|date=26.02.2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482580
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27108355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828408
|full-text-url=https://sci-hub.do/10.1016/j.forsciint.2016.03.047
}}
}}
* {{medline-title
* {{medline-title
|title=Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming.
|title=Evaluation of DNA methylation markers and their potential to predict human aging.
|date=05.2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26010003
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.004
|full-text-url=https://sci-hub.do/10.1002/elps.201500137
}}
}}
==LIF==
==GRIK2==


* {{medline-title
* {{medline-title
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity.
|title=Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2.
|date=25.06.2019
|date=11-12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099472
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675648
}}
}}
* {{medline-title
* {{medline-title
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.
|title=Isoforms of Ionotropic Glutamate Receptor [[GRIK2]] Induce Senescence of Carcinoma Cells.
|date=15.03.2019
|date=01-02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30587499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348395
}}
}}
==LONP1==
==GRIN2B==


* {{medline-title
* {{medline-title
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence.
|title=Medial temporal lobe atrophy relates more strongly to sleep-wake rhythm fragmentation than to age or any other known risk.
|date=15.03.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29864525
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2018.05.017
}}
}}
* {{medline-title
* {{medline-title
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.
|title=Gene Expression Switching of Receptor Subunits in Human Brain Development.
|date=01.02.2019
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26636753
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670163
}}
}}
==LOXL2==
==GRM3==


* {{medline-title
* {{medline-title
|title=Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice.
|title=Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk.
|date=27.09.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31569601
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32203495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801581
|full-text-url=https://sci-hub.do/10.1038/s41593-020-0604-z
}}
}}
* {{medline-title
* {{medline-title
|title=Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening.
|title=Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models.
|date=01.07.2019
|date=30.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002285
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27265785
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692735
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135662
}}
}}
==LRP4==
==GRSF1==


* {{medline-title
* {{medline-title
|title=Multiple MuSK signaling pathways and the aging neuromuscular junction.
|title=[[GRSF1]] is an age-related regulator of senescence.
|date=13.07.2020
|date=03.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32353380
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944385
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2020.135014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447602
}}
}}
* {{medline-title
* {{medline-title
|title=Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing [[LRP4]].
|title=[[GRSF1]] suppresses cell senescence.
|date=10.10.2018
|date=07.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171091
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30086537
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181315
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128438
}}
}}
==LRP5==
==GSTA1==


* {{medline-title
* {{medline-title
|title=[[LRP5]] in age-related changes in vascular and alveolar morphogenesis in the lung.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=05.01.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30612120
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339783
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
* {{medline-title
* {{medline-title
|title=Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.
|title=Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.
|date=07.11.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30404864
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25001375
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aau7137
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150915
}}
}}
==LSR==
==GSTA4==


* {{medline-title
* {{medline-title
|title=Age-related changes in regiospecific expression of Lipolysis Stimulated Receptor ([[LSR]]) in mice brain.
|title=Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue.
|date=2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31233547
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590887
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.013
}}
}}
* {{medline-title
* {{medline-title
|title=Discriminating Alzheimer's disease progression using a new hippocampal marker from T1-weighted MRI: The local surface roughness.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=01.04.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451343
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865478
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==LTB==
==GSTM3==


* {{medline-title
* {{medline-title
|title=Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA + DHA.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=06.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30535619
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://sci-hub.do/10.1007/s10753-018-0949-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
* {{medline-title
* {{medline-title
|title=Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis.
|title=Relationship Between the Altered Expression and Epigenetics of [[GSTM3]] and Age-Related Cataract.
|date=11.2017
|date=01.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803166
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27607418
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.07.043
|full-text-url=https://sci-hub.do/10.1167/iovs.16-19242
}}
}}
==MALT1==
==GSTZ1==


* {{medline-title
* {{medline-title
|title=MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=29.04.2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32350248
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190641
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
* {{medline-title
* {{medline-title
|title=[[MALT1]]-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging.
|title=Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.
|date=2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31632405
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25001375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779721
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150915
}}
}}
==MAP1LC3B==
==HAMP==


* {{medline-title
* {{medline-title
|title=The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells.
|title=A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity.
|date=01.09.2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29408220
|full-text-url=https://sci-hub.do/10.1556/2060.105.2018.3.20
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.01.044
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|title=Longitudinal Relationships between Reproductive Hormones and Cognitive Decline in Older Men: The Concord Health and Ageing in Men Project.
|date=2018
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25867811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
|full-text-url=https://sci-hub.do/10.1210/jc.2015-1016
}}
}}
==MAPK14==
==HAPLN1==


* {{medline-title
* {{medline-title
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|title=Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility.
|date=10.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328333
}}
}}
* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Age-Related Changes in [[HAPLN1]] Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis.
|date=15.11.2017
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328344
}}
}}
==MAPK3==
==HAS1==


* {{medline-title
* {{medline-title
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=04.2019
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
* {{medline-title
* {{medline-title
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts.
|date=10.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
|full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7
}}
}}
==MAPKAPK2==
==HBD==


* {{medline-title
* {{medline-title
|title=Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks.
|title=Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection.
|date=03.12.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31801093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485713
}}
}}
* {{medline-title
* {{medline-title
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|title=Differences in Cytokine Production during Aging and Its Relationship with Antimicrobial Peptides Production.
|date=07.2019
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27618158
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
|full-text-url=https://sci-hub.do/10.1080/08820139.2016.1212873
}}
}}
==MARCO==
==HCN3==


* {{medline-title
* {{medline-title
|title=Age-dependent effect between [[MARCO]] and [[TLR4]] on PMMA particle phagocytosis by macrophages.
|title=Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes.
|date=08.2019
|date=11.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225947
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653467
|full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000455
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria.
|title=Integromics network meta-analysis on cardiac aging offers robust multi-layer modular signatures and reveals micronome synergism.
|date=01.11.2017
|date=04.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28947541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25887273
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679440
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367845
}}
}}
==MCL1==
==HGD==


* {{medline-title
* {{medline-title
|title=[[MCL1]] gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway.
|title=High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans.
|date=01.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30296359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31846489
|full-text-url=https://sci-hub.do/10.1002/iub.1944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917275
}}
}}
* {{medline-title
* {{medline-title
|title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
|title=A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of [i]C. elegans[/i].
|date=10.08.2017
|date=05.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299269
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224263
}}
}}
==MCM2==
==HIF1A==


* {{medline-title
* {{medline-title
|title=Trophoblast type-specific expression of senescence markers in the human placenta.
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|date=15.09.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327484
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|full-text-url=https://sci-hub.do/10.1016/j.placenta.2019.06.377
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=Role of Mitochondrial Complex IV in Age-Dependent Obesity.
|date=27.07.2019
|date=13.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27626667
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2016.08.041
}}
}}
==MCM7==
==HK2==


* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury.
|date=27.07.2019
|date=11.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326403
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811244
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|title=Differentially expressed microRNAs in bone marrow mesenchymal stem cell-derived microvesicles in young and older rats and their effect on tumor growth factor-β1-mediated epithelial-mesenchymal transition in [[HK2]] cells.
|date=08.01.2018
|date=28.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26415502
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587922
}}
}}
==MDH1==
==HLA-B==


* {{medline-title
* {{medline-title
|title=Oxidative Damage to the TCA Cycle Enzyme [[MDH1]] Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=03.04.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32175745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00861
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
* {{medline-title
* {{medline-title
|title=Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro.
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|date=08.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
}}
}}
==MEIS1==
==HLA-C==


* {{medline-title
* {{medline-title
|title=Down-regulation of [[MEIS1]] promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=06.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529342
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|date=11.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
}}
}}
==MIF==
==HLA-DPB1==


* {{medline-title
* {{medline-title
|title=Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice.
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|date=09.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31381889
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
}}
}}
* {{medline-title
* {{medline-title
|title=Macrophage migration inhibitory factor knockdown inhibit viability and induce apoptosis of PVM/Ms.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=12.2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28990052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==MLH1==
==HLA-DQA1==


* {{medline-title
* {{medline-title
|title=The somatic mutation landscape of the human body.
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|date=24.12.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31874648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
}}
}}
* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=[Clinical and genetic characteristics of long-livers in Moscow region].
|date=25.02.2019
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
 
}}
}}
==MMP3==
==HLA-DQB1==


* {{medline-title
* {{medline-title
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|title=Identification of new genetic variants of [[HLA-DQB1]] associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population.
|date=14.11.2017
|date=10.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129831
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723689
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of a pyridine derivative inducing senescence in ovarian cancer cell lines via P21 activation.
|title=[Clinical and genetic characteristics of long-livers in Moscow region].
|date=05.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143360
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693
|full-text-url=https://sci-hub.do/10.1111/1440-1681.12891
 
}}
}}
==MTM1==
==HMGCS1==


* {{medline-title
* {{medline-title
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.
|title=The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
|date=20.03.2019
|date=15.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125687
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.08.003
}}
}}
* {{medline-title
* {{medline-title
|title=Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy.
|title=Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging.
|date=19.11.2018
|date=16.09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451843
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25187565
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169931
}}
}}
==MTMR14==
==HNRNPA1==


* {{medline-title
* {{medline-title
|title=EDTP/[[MTMR14]]: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates.
|title=[[HNRNPA1]]-mediated 3' UTR length changes of [i]HN1[/i] contributes to cancer- and senescence-associated phenotypes.
|date=13.07.2019
|date=30.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31029679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257225
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2019.04.053
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660030
}}
}}
* {{medline-title
* {{medline-title
|title=Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster.
|title=Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans.
|date=16.02.2019
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30528881
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27363602
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.12.009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013025
}}
}}
==MVD==
==HOPX==


* {{medline-title
* {{medline-title
|title=Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density.
|title=Combinations of differentiation markers distinguish subpopulations of alveolar epithelial cells in adult lung.
|date=12.2018
|date=15.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297390
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26545903
|full-text-url=https://sci-hub.do/10.1136/jim-2018-000804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719049
}}
}}
* {{medline-title
* {{medline-title
|title=Assessing Microvascular Function in Humans from a Chronic Disease Perspective.
|title=[[HOPX]] is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer.
|date=12.2017
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904002
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25345926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698072
|full-text-url=https://sci-hub.do/10.1002/path.4469
}}
}}
==NAV2==
==HOXC4==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=10.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Differential DNA Methylation in Relation to Age and Health Risks of Obesity.
|date=07.2018
|date=24.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26213922
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581172
}}
}}
==NCL==
==HPD==


* {{medline-title
* {{medline-title
|title=Factors Affecting Microvascular Responses in the Bulbar Conjunctiva in Habitual Contact Lens Wearers.
|title=Protein-Amino Acid Metabolism Disarrangements: The Hidden Enemy of Chronic Age-Related Conditions.
|date=01.08.2018
|date=22.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30098199
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29565819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946176
}}
}}
* {{medline-title
* {{medline-title
|title=Small nucleoli are a cellular hallmark of longevity.
|title=Post-weaning parental care increases fitness but is not heritable in North American red squirrels.
|date=30.08.2017
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28853436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25847376
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582349
|full-text-url=https://sci-hub.do/10.1111/jeb.12633
}}
}}
==NDNF==
==HRG==


* {{medline-title
* {{medline-title
|title=Effect of neuron-derived neurotrophic factor on rejuvenation of human adipose-derived stem cells for cardiac repair after myocardial infarction.
|title=Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice.
|date=09.2019
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287219
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29021712
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628339
}}
}}
* {{medline-title
* {{medline-title
|title=Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury.
|title=Heregulin, a new regulator of telomere length in human cells.
|date=12.2017
|date=24.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30062183
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26318724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741836
}}
}}
==NDUFB8==
==HSD3B2==


* {{medline-title
* {{medline-title
|title=Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats.
|title=11-Oxygenated C19 Steroids Do Not Decline With Age in Women.
|date=23.05.2018
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29882895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753518
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525564
}}
}}
* {{medline-title
* {{medline-title
|title=Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions.
|title=Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs.
|date=06.2018
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29802507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28166986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060193
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2016.11.007
}}
}}
==NECTIN2==
==HSP90AA1==


* {{medline-title
* {{medline-title
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=08.10.2018
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
* {{medline-title
* {{medline-title
|title=Apolipoprotein E region molecular signatures of Alzheimer's disease.
|title=Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.
|date=08.2018
|date=31.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797398
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26025364
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521048
}}
}}
==NLRC4==
==HSPB1==


* {{medline-title
* {{medline-title
|title=Hyperglycemia-induced inflamm-aging accelerates gingival senescence via [[NLRC4]] phosphorylation.
|title=The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity.
|date=06.12.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31676687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901307
|full-text-url=https://sci-hub.do/10.1016/j.diabres.2019.05.009
}}
}}
* {{medline-title
* {{medline-title
|title=Contribution of the inflammasome to inflammaging.
|title=Chicken heat shock protein [[HSPB1]] increases and interacts with αB-crystallin in aged skeletal muscle.
|date=2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30473634
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26139560
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240324
|full-text-url=https://sci-hub.do/10.1080/09168451.2015.1061419
}}
}}
==NMNAT1==
==HSPB6==


* {{medline-title
* {{medline-title
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=06.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Apoptosis in muscle-to-meat aging process: The omic witness.
|date=12.2017
|date=01.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25956426
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2015.04.023
}}
}}
==NMNAT2==
==HTRA1==


* {{medline-title
* {{medline-title
|title=[[NMNAT2]]-mediated NAD  generation is essential for quality control of aged oocytes.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=06.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909324
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
* {{medline-title
* {{medline-title
|title=Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.
|title=Fibrotic-like changes in degenerate human intervertebral discs revealed by quantitative proteomic analysis.
|date=03.10.2017
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26463451
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640801
|full-text-url=https://sci-hub.do/10.1016/j.joca.2015.09.020
}}
}}
==NNMT==
==HUS1==


* {{medline-title
* {{medline-title
|title=Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle.
|title=Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes.
|date=05.2019
|date=19.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26477511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609912
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy.
|title=[Role of DNA repair genes in radiation-induced changes of lifespan of Drosophila melanogaster].
|date=09.2018
|date=09-10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30192747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25775840
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191153
 
}}
}}
==NOP10==
==IAPP==


* {{medline-title
* {{medline-title
|title=Pseudouridylation defect due to [i]DKC1[/i] and [i][[NOP10]][/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis.
|title=Protein aggregates and proteostasis in aging: Amylin and β-cell function.
|date=30.06.2020
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554502
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334496
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.03.010
}}
}}
* {{medline-title
* {{medline-title
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|title=Causative factors for formation of toxic islet amyloid polypeptide oligomer in type 2 diabetes mellitus.
|date=04.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26604727
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655906
}}
}}
==NOS2==
==ICAM1==


* {{medline-title
* {{medline-title
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity.
|title=An Inhibitor of Activated Blood Coagulation Factor X Shows Anti-Endothelial Senescence and Anti-Atherosclerotic Effects.
|date=10.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31266015
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3
|full-text-url=https://sci-hub.do/10.1159/000499975
}}
}}
* {{medline-title
* {{medline-title
|title=Secreted α-Klotho maintains cartilage tissue homeostasis by repressing [i][[NOS2]][/i] and [i]ZIP8-MMP13[/i] catabolic axis.
|title=Effect of age on expression of spermatogonial markers in bovine testis and isolated cells.
|date=19.06.2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29920476
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27180120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046234
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2016.04.004
}}
}}
==NOTCH3==
==ID3==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|date=16.08.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
}}
}}
* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=06.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==NPR1==
==IFIT1==


* {{medline-title
* {{medline-title
|title=The [[NPR1]]-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana.
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|date=03.12.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33270345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|full-text-url=https://sci-hub.do/10.1111/jipb.13044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis.
|title=Progression of pathology in [[PINK1]]-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.
|date=07.2020
|date=02.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32540002
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28768533
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2020.110472
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541666
}}
}}
==NRK==
==IFIT3==


* {{medline-title
* {{medline-title
|title=[Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/[[ULK1]] signaling activation].
|title=Progression of pathology in [[PINK1]]-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.
|date=03.2019
|date=02.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989992
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28768533
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20181205.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541666
}}
}}
* {{medline-title
* {{medline-title
|title=Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-[[ULK1]] signaling-mediated autophagy.
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=24.12.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585174
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326678
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
==NTS==
==IFNAR1==


* {{medline-title
* {{medline-title
|title=Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension.
|title=Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression.
|date=08.2019
|date=05.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140326
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27052162
|full-text-url=https://sci-hub.do/10.1080/07420528.2019.1613424
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826807
}}
}}
* {{medline-title
* {{medline-title
|title=Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats.
|title=Type 1 interferons contribute to the clearance of senescent cell.
|date=01.08.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26046815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019141
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622626
}}
}}
==OAT==
==IGFBP1==


* {{medline-title
* {{medline-title
|title=Opioid agonist treatment reduces losses in quality of life and quality-adjusted life expectancy in heroin users: Evidence from real world data.
|title=Role of [[IGFBP1]] in the senescence of vascular endothelial cells and severity of aging‑related coronary atherosclerosis.
|date=01.08.2019
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545483
|full-text-url=https://sci-hub.do/10.1016/j.drugalcdep.2019.05.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777673
}}
}}
* {{medline-title
* {{medline-title
|title=Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats.
|title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age.
|date=02.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712161
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00663-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781
}}
}}
==PAK1==
==IGFBP4==


* {{medline-title
* {{medline-title
|title=1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating [[PAK1]] at nM levels.
|title=Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey.
|date=2018
|date=11.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31601169
|full-text-url=https://sci-hub.do/10.5582/ddt.2018.01018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788010
}}
}}
* {{medline-title
* {{medline-title
|title=From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic [[PAK1]]-blockers/longevity-promoters for cancer therapy.
|title=Age-Related Insulin-Like Growth Factor Binding Protein-4 Overexpression Inhibits Osteogenic Differentiation of Rat Mesenchymal Stem Cells.
|date=15.12.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814374
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28595186
|full-text-url=https://sci-hub.do/10.1016/j.ejmech.2017.07.043
|full-text-url=https://sci-hub.do/10.1159/000477873
}}
}}
==PAPPA==
==IHH==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway.
|date=02.2018
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32235006
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185126
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Transfection of the [[IHH]] gene into rabbit BMSCs in a simulated microgravity environment promotes chondrogenic differentiation and inhibits cartilage aging.
|date=12.2017
|date=27.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27802423
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325333
}}
}}
==PDC==
==IL13==


* {{medline-title
* {{medline-title
|title=The mitochondrial translocase of the inner membrane PaTim54 is involved in defense response and longevity in Podospora anserina.
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|date=11.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31351193
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|full-text-url=https://sci-hub.do/10.1016/j.fgb.2019.103257
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
}}
}}
* {{medline-title
* {{medline-title
|title=Neuron-specific knockdown of Drosophila [[PDHB]] induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting.
|title=[[IL10]]-driven [[STAT3]] signalling in senescent macrophages promotes pathological eye angiogenesis.
|date=15.05.2018
|date=11.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501567
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26260587
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.02.035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918330
}}
}}
==PDCD4==
==IL1R2==


* {{medline-title
* {{medline-title
|title=Petal abscission in roses is associated with the activation of a truncated version of the animal [[PDCD4]] homologue, RbPCD1.
|title=Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin.
|date=11.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521226
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28777886
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2019.110242
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721243
}}
}}
* {{medline-title
* {{medline-title
|title=[[PDCD4]] Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression.
|title=A genome-wide scan reveals important roles of DNA methylation in human longevity by regulating age-related disease genes.
|date=2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30687637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25793257
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368809
}}
}}
==PDE4D==
==IL6R==


* {{medline-title
* {{medline-title
|title=Phosphodiesterase [[PDE4D]] Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau.
|title=Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells.
|date=2020
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33192469
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28329136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655962
|full-text-url=https://sci-hub.do/10.1093/gerona/glw336
}}
}}
* {{medline-title
* {{medline-title
|title=Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function.
|title=No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.
|date=02.12.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30409425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946122
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.180
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709
}}
}}
==PER1==
==IL7==


* {{medline-title
* {{medline-title
|title=Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells.
|title=[[SCAMP4]] enhances the senescent cell secretome.
|date=02.2020
|date=01.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31773385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967290
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05194-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075036
}}
}}
* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=Thymic Atrophy: Experimental Studies and Therapeutic Interventions.
|date=21.11.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28960415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://sci-hub.do/10.1111/sji.12618
}}
}}
==PF4==
==ILDR1==


* {{medline-title
* {{medline-title
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|title=Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment.
|date=07.2019
|date=23.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31645637
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811684
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of collagen peptides intake on skin ageing and platelet release in chronologically aged mice revealed by cytokine array analysis.
|title=A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records.
|date=01.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28922541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27764096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742730
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072625
}}
}}
==PGD==
==ING1==


* {{medline-title
* {{medline-title
|title=Primary Care for the Elderly Bereaved: Recommendations for Medical Education.
|title=Impaired DNA demethylation of C/EBP sites causes premature aging.
|date=12.2018
|date=01.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29500657
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29884649
|full-text-url=https://sci-hub.do/10.1007/s10880-018-9556-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049513
}}
}}
* {{medline-title
* {{medline-title
|title=High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles.
|title=The tumor suppressor [[ING1]]b is a novel corepressor for the androgen receptor and induces cellular senescence in prostate cancer cells.
|date=01.03.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29303233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26993046
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844656
|full-text-url=https://sci-hub.do/10.1093/jmcb/mjw007
}}
}}
==PGP==
==INPP5A==


* {{medline-title
* {{medline-title
|title=Age-associated changes of the intrinsic nervous system in relation with interstitial cells in the pre-weaning goat rumen.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=14.07.2019
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31305258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660047
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats.
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182640
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705109
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
}}
==PIEZO1==
==IQGAP1==


* {{medline-title
* {{medline-title
|title=Niche stiffness underlies the ageing of central nervous system progenitor cells.
|title=[[IQGAP1]]-dysfunction leads to induction of senescence in human vascular smooth muscle cells.
|date=09.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31413369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025879
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111295
}}
}}
* {{medline-title
* {{medline-title
|title=On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, [[PIEZO1]], and Gardos Channels.
|title=Hyaluronan-binding protein 1 (HABP1) overexpression triggers induction of senescence in fibroblasts cells.
|date=2017
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29311949
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32068317
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732905
|full-text-url=https://sci-hub.do/10.1002/cbin.11326
}}
}}
==PIK3CG==
==IRF4==


* {{medline-title
* {{medline-title
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|date=10.06.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
}}
}}
* {{medline-title
* {{medline-title
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|title=Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice.
|date=18.03.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28905935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672072
}}
}}
==PLD2==
==IRGM==


* {{medline-title
* {{medline-title
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=08.2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
* {{medline-title
* {{medline-title
|title=Role of phospholipase D in the lifespan of Caenorhabditis elegans.
|title=Bt Cry1Ie Toxin Does Not Impact the Survival and Pollen Consumption of Chinese Honey Bees, Apis cerana cerana (Hymenoptera, Apidae).
|date=06.04.2018
|date=01.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29622768
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27670271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938010
|full-text-url=https://sci-hub.do/10.1093/jee/tow204
}}
}}
==PLIN2==
==ITGAM==


* {{medline-title
* {{medline-title
|title=Cardiac overexpression of perilipin 2 induces atrial steatosis, connexin 43 remodeling, and atrial fibrillation in aged mice.
|title=Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging.
|date=01.12.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31661297
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31732940
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957375
|full-text-url=https://sci-hub.do/10.1007/978-3-030-28524-1_11
}}
}}
* {{medline-title
* {{medline-title
|title=[[HDAC6]] Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of [[PLIN2]] in Drosophila.
|title=Transcriptomic analysis of purified human cortical microglia reveals age-associated changes.
|date=09.10.2017
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28966044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671693
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2017.09.001
|full-text-url=https://sci-hub.do/10.1038/nn.4597
}}
}}
==PLK4==
==ITGB3==


* {{medline-title
* {{medline-title
|title=A novel lncRNA [[PLK4]] up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence.
|title=Integrin Beta 3 Regulates Cellular Senescence by Activating the TGF-β Pathway.
|date=05.2020
|date=07.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32243714
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28273461
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357738
}}
}}
* {{medline-title
* {{medline-title
|title=Differential expression of AURKA/[[PLK4]] in quiescence and senescence of osteosarcoma U2OS cells.
|title=[Clinical and genetic characteristics of long-livers in Moscow region].
|date=04.2020
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32200684
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217361
 
}}
}}
==POSTN==
==ITK==


* {{medline-title
* {{medline-title
|title=A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals [[POSTN]] As a New Element in Proline Metabolic Disorder.
|title=Does Tetralogy of Fallot affect brain aging? A proof-of-concept study.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103512
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Phenotypic characteristics of aged [[CD4]]  [[CD28]]  T lymphocytes are determined by changes in the whole-genome DNA methylation pattern.
|date=02.2018
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28026094
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334526
}}
}}
==POT1==
==JAK3==


* {{medline-title
* {{medline-title
|title=MiR-185 targets [[POT1]] to induce telomere dysfunction and cellular senescence.
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|date=18.07.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32687062
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425516
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
}}
}}
* {{medline-title
* {{medline-title
|title=Seryl tRNA synthetase cooperates with [[POT1]] to regulate telomere length and cellular senescence.
|title=IL-15 enhances the antitumor effect of human antigen-specific CD8  T cells by cellular senescence delay.
|date=2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31815007
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28123872
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882858
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215241
}}
}}
==PPID==
==KDM2B==


* {{medline-title
* {{medline-title
|title=Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population.
|title=Identification of Structural Elements of the Lysine Specific Demethylase 2B CxxC Domain Associated with Replicative Senescence Bypass in Primary Mouse Cells.
|date=03.2020
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32058159
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270414
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2020.110013
|full-text-url=https://sci-hub.do/10.1007/s10930-020-09895-z
}}
}}
* {{medline-title
* {{medline-title
|title=Epidemiology of pituitary pars intermedia dysfunction: A systematic literature review of clinical presentation, disease prevalence and risk factors.
|title=Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases.
|date=05.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29704935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27114850
|full-text-url=https://sci-hub.do/10.1016/j.tvjl.2018.03.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809609
}}
}}
==PPM1D==
==KDM3A==


* {{medline-title
* {{medline-title
|title=Detectible mosaic truncating [[PPM1D]] mutations, age and breast cancer risk.
|title=[[KDM3A]] and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization.
|date=06.2019
|date=22.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30850729
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704649
|full-text-url=https://sci-hub.do/10.1038/s10038-019-0589-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888768
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related remodelling of oesophageal epithelia by mutated cancer drivers.
|title=Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases.
|date=01.2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30602793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27114850
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0811-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809609
}}
}}
==PRC1==
==KDM6B==


* {{medline-title
* {{medline-title
|title=Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein [[BMI1]] in breast cancer cells.
|title=Histone demethylase [[KDM6B]] regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells.
|date=07.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30825201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986597
|full-text-url=https://sci-hub.do/10.1002/jcp.28431
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster.
|title=Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases.
|date=02.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27114850
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9737-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809609
}}
}}
==PROC==
==KIF1B==


* {{medline-title
* {{medline-title
|title=Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation.
|title=[[BDNF]] trafficking and signaling impairment during early neurodegeneration is prevented by moderate physical activity.
|date=15.04.2020
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30135925
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157190
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084862
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of feeding frequency of an elevated plane of milk replacer and calf age on behavior, and glucose and insulin kinetics in male Holstein calves.
|title=Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis.
|date=07.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30419975
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26954557
|full-text-url=https://sci-hub.do/10.1017/S175173111800294X
|full-text-url=https://sci-hub.do/10.1159/000443664
}}
}}
==PSEN2==
==KIFC3==


* {{medline-title
* {{medline-title
|title=Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human [[PSEN2]].
|title=Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging.
|date=2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31978074
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29845728
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980398
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052466
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition.
|title=Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis.
|date=03.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31862541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26954557
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462087
|full-text-url=https://sci-hub.do/10.1159/000443664
}}
}}
==PTBP1==
==KISS1R==


* {{medline-title
* {{medline-title
|title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence.
|title=Kisspeptin across the human lifespan:evidence from animal studies and beyond.
|date=11.12.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27340201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934
|full-text-url=https://sci-hub.do/10.1530/JOE-15-0538
}}
}}
* {{medline-title
* {{medline-title
|title=[[PTBP1]]-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.
|title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus.
|date=09.07.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990503
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460
}}
}}
==PTPN11==
==KPNA2==


* {{medline-title
* {{medline-title
|title=Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array.
|title=Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-[[CRY1]] Transgenic Mice.
|date=01.10.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32888012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31179341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507265
}}
}}
* {{medline-title
* {{medline-title
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|title=Upregulated Expression of Karyopherin α2 is Involved in Neuronal Apoptosis Following Intracerebral Hemorrhage in Adult Rats.
|date=04.2019
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26340948
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
|full-text-url=https://sci-hub.do/10.1007/s10571-015-0258-7
}}
}}
==PTS==
==KY==


* {{medline-title
* {{medline-title
|title=Posttraumatic stress symptom persistence across 24 years: association with brain structures.
|title=Combination of acupuncture and Chinese herbal formula for elderly adults with mild cognitive impairment: protocol for a randomized controlled trial.
|date=08.2020
|date=11.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30830577
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30744676
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722032
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371495
}}
}}
* {{medline-title
* {{medline-title
|title=Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis.
|title=Cerebrolysin Accelerates Metamorphosis and Attenuates Aging-Accelerating Effect of High Temperature in Drosophila Melanogaster.
|date=18.07.2018
|date=01.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25798213
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367862
}}
}}
==PTX3==
==LAG3==


* {{medline-title
* {{medline-title
|title=Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects.
|title=T Cell Transcriptional Profiling and Immunophenotyping Uncover [[LAG3]] as a Potential Significant Target of Immune Modulation in Multiple Myeloma.
|date=27.01.2020
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012711
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31445183
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070734
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952061
}}
}}
* {{medline-title
* {{medline-title
|title=Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study.
|title=Functional exhaustion of [[CD4]]  T cells induced by co-stimulatory signals from myeloid leukaemia cells.
|date=13.07.2020
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31808814
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27565576
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095494
}}
}}
==PUM2==
==LAMA5==


* {{medline-title
* {{medline-title
|title=PUMILIO hyperactivity drives premature aging of [i]Norad[/i]-deficient mice.
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
|date=08.02.2019
|date=05.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735131
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407921
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
}}
}}
* {{medline-title
* {{medline-title
|title=The RNA-Binding Protein [[PUM2]] Impairs Mitochondrial Dynamics and Mitophagy During Aging.
|title=Association of the Laminin, Alpha 5 ([[LAMA5]]) rs4925386 with height and longevity in an elderly population from Southern Italy.
|date=21.02.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30642763
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26968355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396316
|full-text-url=https://sci-hub.do/10.1016/j.mad.2016.03.003
}}
}}
==PYY==
==LAMC1==


* {{medline-title
* {{medline-title
|title=Peptide YY ([[PYY]]) Is Expressed in Human Skeletal Muscle Tissue and Expanding Human Muscle Progenitor Cells.
|title=Relation of size of seminal vesicles on ultrasound to premature ejaculation.
|date=2019
|date=09-10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27538475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566849
}}
}}
* {{medline-title
* {{medline-title
|title=Peptide YY induces characteristic meal patterns of aged mice.
|title=Discovery and characterization of miRNA during cellular senescence in bone marrow-derived human mesenchymal stem cells.
|date=11.2017
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28916138
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25087724
|full-text-url=https://sci-hub.do/10.1016/j.yhbeh.2017.09.003
|full-text-url=https://sci-hub.do/10.1016/j.exger.2014.07.020
}}
}}
==RAD52==
==LAMP2==


* {{medline-title
* {{medline-title
|title=Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae.
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|date=01.08.2019
|date=07.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075257
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563841
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
}}
}}
* {{medline-title
* {{medline-title
|title=Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human [[RAD52]] gene in a cardiovascular cohort.
|title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers.
|date=10.2017
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024686
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.10.003
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022
}}
}}
==RAG1==
==LAT==


* {{medline-title
* {{medline-title
|title=T cell senescence accelerates Angiotensin II-induced target organ damage.
|title=Is the combined auriculotherapy approach superior to magneto-auriculotherapy alone in aging males with lower urinary tract symptoms? A randomized controlled trial.
|date=12.02.2020
|date=16.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32049355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30651007
|full-text-url=https://sci-hub.do/10.1093/cvr/cvaa032
|full-text-url=https://sci-hub.do/10.1080/13685538.2018.1542673
}}
}}
* {{medline-title
* {{medline-title
|title=Aged murine hematopoietic stem cells drive aging-associated immune remodeling.
|title=Intra-couple Caregiving of Older Adults Living Apart Together: Commitment and Independence.
|date=09.08.2018
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891535
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26300191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137572
|full-text-url=https://sci-hub.do/10.1017/S0714980815000264
}}
}}
==RAN==
==LATS2==


* {{medline-title
* {{medline-title
|title=Rapid automatized naming ([[RAN]]): effects of aging on a predictor of reading skill.
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|date=17.08.2020
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32799742
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|full-text-url=https://sci-hub.do/10.1080/13825585.2020.1806987
 
}}
}}
* {{medline-title
* {{medline-title
|title=SCA8 [[RAN]] polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F.
|title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis.
|date=01.10.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166133
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607
}}
}}
==RGN==
==LDHA==


* {{medline-title
* {{medline-title
|title=Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04.
|title=Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16  inactivation.
|date=2018
|date=26.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29675370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482580
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902356
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828408
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of supplementation of recombinant Regucalcin in extender on cryopreservation of spermatozoa of water buffalo (Bubalus bubalis).
|title=Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming.
|date=11.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782859
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476819
|full-text-url=https://sci-hub.do/10.1002/mrd.22873
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.004
}}
}}
==RIG==
==LDLR==


* {{medline-title
* {{medline-title
|title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling.
|title=Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice.
|date=2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29903737
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092113
}}
}}
* {{medline-title
* {{medline-title
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes.
|title=Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice.
|date=12.12.2017
|date=15.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26592663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.11.064
}}
}}
==RNF8==
==LEPR==


* {{medline-title
* {{medline-title
|title=Expression of [[RNF8]] on cochlear apoptosis and aging in mice of different ages.
|title=Age-related changes of leptin and leptin receptor variants in healthy elderly and long-lived adults.
|date=03-Apr,.2019
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915826
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24612398
 
|full-text-url=https://sci-hub.do/10.1111/ggi.12267
}}
}}
* {{medline-title
* {{medline-title
|title=Function of RAD6B and [[RNF8]] in spermatogenesis.
|title=Functional polymorphisms of the leptin and leptin receptor genes are associated with longevity and with the risk of myocardial infarction and of type 2 diabetes mellitus.
|date=2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825854
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24549597
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884393
|full-text-url=https://sci-hub.do/10.5603/EP.2014.0002
}}
}}
==RPS6==
==LIFR==


* {{medline-title
* {{medline-title
|title=Regulation of Amino Acid Transporters and Sensors in Response to a High protein Diet: A Randomized Controlled Trial in Elderly Men.
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.
|date=2019
|date=15.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30932134
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025
|full-text-url=https://sci-hub.do/10.1007/s12603-019-1171-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107.
|title=Characterization of Nestin-positive stem Leydig cells as a potential source for the treatment of testicular Leydig cell dysfunction.
|date=08.2018
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25418539
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260348
}}
}}
==RTEL1==
==LOXL1==


* {{medline-title
* {{medline-title
|title=Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants.
|title=A blackberry-dill extract combination synergistically increases skin elasticity.
|date=12.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31444995
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32583541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826144
|full-text-url=https://sci-hub.do/10.1111/ics.12644
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide association study of telomere length among South Asians identifies a second [[RTEL1]] association signal.
|title=Methylation of [[LOXL1]] Promoter by [[DNMT3A]] in Aged Human Skin Fibroblasts.
|date=01.2018
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29151059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27396912
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749304
|full-text-url=https://sci-hub.do/10.1089/rej.2016.1832
}}
}}
==RUNX1==
==LRP4==


* {{medline-title
* {{medline-title
|title=RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing [[RUNX1]] fusion oncoproteins.
|title=Multiple MuSK signaling pathways and the aging neuromuscular junction.
|date=03.2018
|date=13.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29052866
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32353380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813226
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2020.135014
}}
}}
* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing [[LRP4]].
|date=2017
|date=10.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171091
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181315
}}
}}
==S100A4==
==LRP5==


* {{medline-title
* {{medline-title
|title=Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice.
|title=[[LRP5]] in age-related changes in vascular and alveolar morphogenesis in the lung.
|date=15.12.2019
|date=05.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678243
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30612120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339783
}}
}}
* {{medline-title
* {{medline-title
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|title=Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.
|date=2018
|date=07.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30404864
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aau7137
}}
}}
==S1PR1==
==LRPPRC==


* {{medline-title
* {{medline-title
|title=Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair.
|title=The loss of [[LRPPRC]] function induces the mitochondrial unfolded protein response.
|date=22.06.2020
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544390
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26412102
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600627
}}
}}
* {{medline-title
* {{medline-title
|title=Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota.
|title=Drosophila melanogaster [[LRPPRC]]2 is involved in coordination of mitochondrial translation.
|date=04.01.2018
|date=16.12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302034
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25428350
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754350
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267620
}}
}}
==SAA1==
==LTB==


* {{medline-title
* {{medline-title
|title=Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells.
|title=Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA  DHA.
|date=2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30535619
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884545
|full-text-url=https://sci-hub.do/10.1007/s10753-018-0949-6
}}
}}
* {{medline-title
* {{medline-title
|title=Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients.
|title=Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis.
|date=2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846716
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803166
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573208
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.07.043
}}
}}
==SCAP==
==LTF==


* {{medline-title
* {{medline-title
|title=Dementia outcomes after addition of proxy-based assessments for deceased or proxy-dependent participants.
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|date=10.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31034676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742525
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
}}
}}
* {{medline-title
* {{medline-title
|title=Increased hepatic INSIG-[[SCAP]]-SREBP expression is associated with cholesterol metabolism disorder in assisted reproductive technology-conceived aged mice.
|title=Effect of age on long-term facilitation and chemosensitivity during NREM sleep.
|date=03.2019
|date=15.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30562550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26316510
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2018.12.003
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00030.2015
}}
}}
==SESN2==
==MALT1==


* {{medline-title
* {{medline-title
|title=Copy Number Alterations in Papillary Thyroid Carcinomas: Does Loss of [i][[SESN2]][/i] Have a Role in Age-related Different Prognoses?
|title=MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity.
|date=09-10.2020
|date=29.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32859642
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32350248
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190641
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea.
|title=[[MALT1]]-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging.
|date=11.10.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28818524
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31632405
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605466
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779721
}}
}}
==SLC25A24==
==MAP1A==


* {{medline-title
* {{medline-title
|title=De Novo Mutations in [[SLC25A24]] Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=02.11.2017
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29100094
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673633
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
* {{medline-title
* {{medline-title
|title=De Novo Mutations in [[SLC25A24]] Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction.
|title=Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.
|date=02.11.2017
|date=21.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29100093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24849348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028492
}}
}}
==SMAD2==
==MAP1LC3B==


* {{medline-title
* {{medline-title
|title=Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation.
|title=The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells.
|date=02.2020
|date=01.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31674011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269563
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071816
|full-text-url=https://sci-hub.do/10.1556/2060.105.2018.3.20
}}
}}
* {{medline-title
* {{medline-title
|title=Restoring extracellular matrix synthesis in senescent stem cells.
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=10.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287964
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766659
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
}}
==SMAD4==
==MAP1S==


* {{medline-title
* {{medline-title
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient.
|title=Defects in [[MAP1S]]-mediated autophagy turnover of fibronectin cause renal fibrosis.
|date=09.2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27236336
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931848
}}
}}
* {{medline-title
* {{medline-title
|title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16  and Wild-Type p53.
|title=Defects in [[MAP1S]]-mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed.
|date=2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26750654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783353
}}
}}
==SNCB==
==MARCO==


* {{medline-title
* {{medline-title
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|title=Age-dependent effect between [[MARCO]] and [[TLR4]] on PMMA particle phagocytosis by macrophages.
|date=08.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225947
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653467
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro.
|title=Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria.
|date=05.2018
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808713
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28947541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679440
}}
}}
==SOCS1==
==MAVS==


* {{medline-title
* {{medline-title
|title=Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus.
|title=Spontaneous activation of a [[MAVS]]-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes.
|date=06.2019
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30656452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822807
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0607-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600710
}}
}}
* {{medline-title
* {{medline-title
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|title=Progression of pathology in [[PINK1]]-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.
|date=28.10.2017
|date=02.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28768533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541666
}}
}}
==SORL1==
==MC1R==


* {{medline-title
* {{medline-title
|title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.
|title=In vitro behavior and UV response of melanocytes derived from carriers of [[[[CDKN2A]]]] mutations and [[MC1R]] variants.
|date=05.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706571
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608707
|full-text-url=https://sci-hub.do/10.1111/pcmr.12732
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.
|title=The [[MC1R]] Gene and Youthful Looks.
|date=2018
|date=09.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27133870
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481
|full-text-url=https://sci-hub.do/10.1016/j.cub.2016.03.008
}}
}}
==SOST==
==MCM3==


* {{medline-title
* {{medline-title
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women.
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=07.2019
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
}}
* {{medline-title
* {{medline-title
|title=Bone adaptation in response to treadmill exercise in young and adult mice.
|title=Up-regulation of [[MCM3]] Relates to Neuronal Apoptosis After Traumatic Brain Injury in Adult Rats.
|date=06.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29379848
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27401074
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787623
|full-text-url=https://sci-hub.do/10.1007/s10571-016-0404-x
}}
}}
==SPARCL1==
==MCM8==


* {{medline-title
* {{medline-title
|title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment.
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|date=18.06.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
}}
}}
* {{medline-title
* {{medline-title
|title=[[SPARCL1]] Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging.
|title=[[MCM8]] and [[MCM9]] Nucleotide Variants in Women With Primary Ovarian Insufficiency.
|date=2018
|date=01.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27802094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934753
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413161
}}
}}
==SPR==
==MCM9==


* {{medline-title
* {{medline-title
|title=Regulation of lifespan by neural excitation and REST.
|title=MCM8- and [[MCM9]] Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors.
|date=10.2019
|date=10.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31619788
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31509747
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893853
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.07.095
}}
}}
* {{medline-title
* {{medline-title
|title=How many geriatricians should, at minimum, be staffing health regions in Australia?
|title=[[MCM8]] and [[MCM9]] Nucleotide Variants in Women With Primary Ovarian Insufficiency.
|date=03.2018
|date=01.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171127
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27802094
|full-text-url=https://sci-hub.do/10.1111/ajag.12467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413161
}}
}}
==SRR==
==MDH1==


* {{medline-title
* {{medline-title
|title=Mediterranean diet and its components in relation to all-cause mortality: meta-analysis.
|title=Oxidative Damage to the TCA Cycle Enzyme [[MDH1]] Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain.
|date=11.2018
|date=03.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30401007
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32175745
|full-text-url=https://sci-hub.do/10.1017/S0007114518002593
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00861
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|title=Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro.
|date=2017
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850038
}}
}}
==SSB==
==ME1==


* {{medline-title
* {{medline-title
|title=Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study.
|title=NADP-MALIC ENZYME 1 Affects Germination after Seed Storage in Arabidopsis thaliana.
|date=03.12.2019
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816850
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30388244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950484
|full-text-url=https://sci-hub.do/10.1093/pcp/pcy213
}}
}}
* {{medline-title
* {{medline-title
|title=WHIRLY1 Occupancy Affects Histone Lysine Modification and [i]WRKY53[/i] Transcription in [i]Arabidopsis[/i] Developmental Manner.
|title=Down-regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy-induced senescence.
|date=2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30405658
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25994759
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202938
|full-text-url=https://sci-hub.do/10.1002/hed.24129
}}
}}
==STAT5A==
==ME2==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=A small-molecule inhibitor suppresses the tumor-associated mitochondrial NAD(P) -dependent malic enzyme ([[ME2]]) and induces cellular senescence.
|date=15.11.2018
|date=21.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26008970
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652989
}}
}}
* {{medline-title
* {{medline-title
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|title=Down-regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy-induced senescence.
|date=28.10.2017
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25994759
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
|full-text-url=https://sci-hub.do/10.1002/hed.24129
}}
}}
==STIM1==
==MEF2D==


* {{medline-title
* {{medline-title
|title=Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis.
|title=Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency.
|date=02.2020
|date=01.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31833196
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28738418
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996945
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525556
}}
}}
* {{medline-title
* {{medline-title
|title=Ca  entry via [[TRPC1]] is essential for cellular differentiation and modulates secretion via the SNARE complex.
|title=Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem.
|date=01.07.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182642
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25184702
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153547
}}
}}
==SUV39H1==
==MEIS1==


* {{medline-title
* {{medline-title
|title=Increase in hippocampal histone H3K9me3 is negatively correlated with memory in old male mice.
|title=Down-regulation of [[MEIS1]] promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes.
|date=04.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31760560
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884246
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09850-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529342
}}
}}
* {{medline-title
* {{medline-title
|title=Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=27.09.2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952292
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==SV2A==
==MEOX2==


* {{medline-title
* {{medline-title
|title=Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging.
|title=Reduced expression of microRNA-130a promotes endothelial cell senescence and age-dependent impairment of neovascularization.
|date=01.10.2018
|date=26.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30014145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32457253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346016
}}
}}
* {{medline-title
* {{medline-title
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|title=Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease.
|date=10.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27143421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878023
}}
}}
==TAS2R16==
==MFN1==


* {{medline-title
* {{medline-title
|title=Taste receptor polymorphisms and longevity: a systematic review and meta-analysis.
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.
|date=10.11.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33170488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01745-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
}}
}}
* {{medline-title
* {{medline-title
|title=Taste receptors, innate immunity and longevity: the case of [[TAS2R16]] gene.
|title=Mitofusin 1 and optic atrophy 1 shift metabolism to mitochondrial respiration during aging.
|date=2019
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30833980
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28758339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387736
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595680
}}
}}
==TAS2R38==
==MGAT1==


* {{medline-title
* {{medline-title
|title=[[TAS2R38]] bitter taste receptor and attainment of exceptional longevity.
|title=Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence.
|date=02.12.2019
|date=28.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792278
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28105936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889489
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249001
}}
}}
* {{medline-title
* {{medline-title
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects.
|title=Transcriptional and biochemical responses of monoacylglycerol acyltransferase-mediated oil synthesis and associated senescence-like responses in Nicotiana benthamiana.
|date=18.10.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24904604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033622
}}
}}
==TAT==
==MICA==


* {{medline-title
* {{medline-title
|title=Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides.
|title=Derivation and Validation of a Geriatric-Sensitive Perioperative Cardiac Risk Index.
|date=2019
|date=16.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31024341
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467974
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721761
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of HIV-1 gp120 and [[TAT]]-derived microvesicles on endothelial cell function.
|title=NKG2D ligands mediate immunosurveillance of senescent cells.
|date=01.05.2019
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789287
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26878797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589811
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789586
}}
}}
==TBC1D5==
==MKI67==


* {{medline-title
* {{medline-title
|title=[[TBC1D5]]-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry.
|title=Evidence for reduced neurogenesis in the aging human hippocampus despite stable stem cell markers.
|date=09.06.2020
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32521275
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28766905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595679
}}
}}
* {{medline-title
* {{medline-title
|title=Retromer and [[TBC1D5]] maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling.
|title=[Epigenetic aspects of peptidergic regulation of vascular endothelial cell proliferation during aging].
|date=02.09.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31431476
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25051766
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719456
 
}}
}}
==TBK1==
==MLH1==


* {{medline-title
* {{medline-title
|title=Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of [[TBK1]] to facilitate mitophagy.
|title=The somatic mutation landscape of the human body.
|date=01.01.2021
|date=24.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33164878
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31874648
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165997
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930685
}}
}}
* {{medline-title
* {{medline-title
|title=[[TBK1]] Suppresses [[RIPK1]]-Driven Apoptosis and Inflammation during Development and in Aging.
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=06.09.2018
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30146158
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128749
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
}}
==TCF7L2==
==MNT==


* {{medline-title
* {{medline-title
|title=A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder.
|title=Application of a handheld Pressure Application Measurement device for the characterisation of mechanical nociceptive thresholds in intact pig tails.
|date=03.2020
|date=15.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32015540
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27422675
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038977
}}
}}
* {{medline-title
* {{medline-title
|title=Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle.
|title=Performance of the Maze Navigation Test in a sample of older New Zealanders.
|date=01.03.2019
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30824849
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26229055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397284
|full-text-url=https://sci-hub.do/10.1177/1039856215597541
}}
}}
==TIMELESS==
==MR1==


* {{medline-title
* {{medline-title
|title=Loss of circadian protein [[TIMELESS]] accelerates the progression of cellular senescence.
|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers.
|date=18.09.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30100061
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.040
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826
}}
}}
* {{medline-title
* {{medline-title
|title=Clock gene expression and locomotor activity predict death in the last days of life in Drosophila melanogaster.
|title=Aging-associated formaldehyde-induced norepinephrine deficiency contributes to age-related memory decline.
|date=09.08.2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30093652
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25866202
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085321
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531079
}}
}}
==TIMP1==
==MRPS5==


* {{medline-title
* {{medline-title
|title=Design, cyclization, and optimization of [[MMP13]]-[[TIMP1]] interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis.
|title=Mutant [[MRPS5]] affects mitoribosomal accuracy and confers stress-related behavioral alterations.
|date=01.2019
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352228
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30237157
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.10.141
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216279
}}
}}
* {{medline-title
* {{medline-title
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa.
|date=2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417
}}
}}
==TLR7==
==MS4A6E==


* {{medline-title
* {{medline-title
|title=Bovine Lactoferrin Enhances [[TLR7]]-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D.
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=2018
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515164
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255898
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
}}
* {{medline-title
* {{medline-title
|title=B cell responses to apoptotic cells in MFG-E8-/- mice.
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30286201
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171925
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
}}
==TMPRSS2==
==MSH2==


* {{medline-title
* {{medline-title
|title=Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants.
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=09.09.2020
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32905655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://sci-hub.do/10.1002/jbt.22626
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of the SARS-CoV-2 Entry Proteins, ACE2 and [[TMPRSS2]], in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age.
|title=Age-dependent changes in DNA repair in radiation-exposed mice.
|date=03.06.2020
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32379417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25409128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241737
|full-text-url=https://sci-hub.do/10.1667/RR13697.1
}}
}}
==TNNT3==
==MT2A==


* {{medline-title
* {{medline-title
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|title=Metallothionein Prevents Age-Associated Cardiomyopathy via Inhibiting NF-κB Pathway Activation and Associated Nitrative Damage to 2-OGD.
|date=06.02.2019
|date=10.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27477335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144888
}}
}}
* {{medline-title
* {{medline-title
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.
|title=Metallothioneins and renal ageing.
|date=15.07.2018
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26908771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179
|full-text-url=https://sci-hub.do/10.1093/ndt/gfv451
}}
}}
==TPO==
==MTM1==


* {{medline-title
* {{medline-title
|title=Megakaryocytes promote osteoclastogenesis in aging.
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.
|date=07.07.2020
|date=20.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425434
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866
}}
}}
* {{medline-title
* {{medline-title
|title=To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex-independent) NOD.H2  mice.
|title=Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy.
|date=04.2019
|date=19.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566234
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451843
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243013
}}
}}
==TREX1==
==MTRR==


* {{medline-title
* {{medline-title
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|title=One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults.
|date=2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208817
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.05.013
}}
}}
* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=[Clinical and genetic characteristics of long-livers in Moscow region].
|date=06.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
 
}}
}}
==TRH==
==MUC2==


* {{medline-title
* {{medline-title
|title=Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats.
|title=[[KLF4]] deletion alters gastric cell lineage and induces [[MUC2]] expression.
|date=15.03.2018
|date=09.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29305326
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27277677
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2017.12.029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143387
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of dietary carbohydrates and time of year on ACTH and cortisol concentrations in adult and aged horses.
|title=Early intestinal development and mucin transcription in the young poult with probiotic and mannan oligosaccharide prebiotic supplementation.
|date=04.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195115
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26944966
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2017.10.005
|full-text-url=https://sci-hub.do/10.3382/ps/pew019
}}
}}
==TRPC6==
==MYBPC3==


* {{medline-title
* {{medline-title
|title=Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype.
|title=Compound heterozygosity deteriorates phenotypes of hypertrophic cardiomyopathy with founder [[MYBPC3]] mutation: evidence from patients and zebrafish models.
|date=11.2020
|date=01.12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32686475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25281569
|full-text-url=https://sci-hub.do/10.1177/1535370220943122
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00637.2013
}}
}}
* {{medline-title
* {{medline-title
|title=[[TRPC6]] in simulated microgravity of intervertebral disc cells.
|title=Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-[[MADD]] locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=10.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29968164
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951664
|full-text-url=https://sci-hub.do/10.1007/s00586-018-5688-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066205
}}
}}
==TRPM7==
==MYOD1==


* {{medline-title
* {{medline-title
|title=mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development.
|title=Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice.
|date=10.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29842890
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27224259
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.05.008
|full-text-url=https://sci-hub.do/10.1111/dgd.12290
}}
}}
* {{medline-title
* {{medline-title
|title=Role of kinase-coupled TRP channels in mineral homeostasis.
|title=Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model.
|date=04.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26861500
|full-text-url=https://sci-hub.do/10.1016/j.pharmthera.2017.11.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798846
}}
}}
==TRPM8==
==NAT2==


* {{medline-title
* {{medline-title
|title=Morphological and functional changes in [[TRPM8]]-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice.
|title=Lifestyle and clinical determinants of skin autofluorescence in a population-based cohort study.
|date=01.08.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29664111
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27002914
|full-text-url=https://sci-hub.do/10.1002/cne.24454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111733
}}
}}
* {{medline-title
* {{medline-title
|title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases.
|title=The ultra-slow [[NAT2]]*6A haplotype is associated with reduced higher cognitive functions in an elderly study group.
|date=02.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26615528
|full-text-url=https://sci-hub.do/10.1111/nmo.13185
|full-text-url=https://sci-hub.do/10.1007/s00204-015-1635-1
}}
}}
==TTN==
==NAV2==


* {{medline-title
* {{medline-title
|title=LncRNA [[TTN]]-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis.
|title=Genetic associations with age of menopause in familial longevity.
|date=10.10.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31600142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814585
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=15.11.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==TXNRD2==
==NBN==


* {{medline-title
* {{medline-title
|title=Wogonin induces cellular senescence in breast cancer via suppressing [[TXNRD2]] expression.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=10.2020
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32671444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://sci-hub.do/10.1007/s00204-020-02842-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of [[IDH2]] Accelerates Age-related Hearing Loss in Male Mice.
|title=Circulating T Cells of Patients with Nijmegen Breakage Syndrome Show Signs of Senescence.
|date=22.03.2018
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567975
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28000062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325864
}}
}}
==VCAM1==
==NBR1==


* {{medline-title
* {{medline-title
|title=Sunitinib facilitates metastatic breast cancer spreading by inducing endothelial cell senescence.
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
|date=29.09.2020
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32993785
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526390
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049
}}
}}
* {{medline-title
* {{medline-title
|title=Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell [[VCAM1]].
|title=Overweight in elderly people induces impaired autophagy in skeletal muscle.
|date=06.2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31086348
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28549989
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642642
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.05.018
}}
}}
==VCAN==
==NDNF==


* {{medline-title
* {{medline-title
|title=Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis.
|title=Effect of neuron-derived neurotrophic factor on rejuvenation of human adipose-derived stem cells for cardiac repair after myocardial infarction.
|date=07.06.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31051334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287219
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495079
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714174
}}
}}
* {{medline-title
* {{medline-title
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.
|title=Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury.
|date=2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30062183
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059002
}}
}}
==WFS1==
==NDUFS1==


* {{medline-title
* {{medline-title
|title=Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila.
|title=Mapping the protein phosphorylation sites in human mitochondrial complex I (NADH: Ubiquinone oxidoreductase): A bioinformatics study with implications for brain aging and neurodegeneration.
|date=01.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29357349
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29499254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794194
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2018.02.004
}}
}}
* {{medline-title
* {{medline-title
|title=A nonsynonymous mutation in the [[WFS1]] gene in a Finnish family with age-related hearing impairment.
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
|date=11.2017
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28974383
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499
|full-text-url=https://sci-hub.do/10.1016/j.heares.2017.09.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201
}}
}}
==WIPI2==
==NDUFV2==


* {{medline-title
* {{medline-title
|title=Neuronal autophagy declines substantially with age and is rescued by overexpression of [[WIPI2]].
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=02.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
* {{medline-title
* {{medline-title
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|title=The Effect of Aging on Mitochondrial Complex I and the Extent of Oxidative Stress in the Rat Brain Cortex.
|date=04.2019
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27161369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
|full-text-url=https://sci-hub.do/10.1007/s11064-016-1931-z
}}
}}
==XRCC1==
==NECTIN2==


* {{medline-title
* {{medline-title
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats].
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|date=07.2018
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180408.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
}}
}}
* {{medline-title
* {{medline-title
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.
|title=Apolipoprotein E region molecular signatures of Alzheimer's disease.
|date=2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797398
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052488
}}
}}
==YAP1==
==NEFM==


* {{medline-title
* {{medline-title
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|title=Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age.
|date=25.06.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30927131
 
|full-text-url=https://sci-hub.do/10.1007/s10735-019-09820-4
}}
}}
* {{medline-title
* {{medline-title
|title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis.
|title=The Alzheimer's disease transcriptome mimics the neuroprotective signature of IGF-1 receptor-deficient neurons.
|date=03.2019
|date=01.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28595357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607
|full-text-url=https://sci-hub.do/10.1093/brain/awx132
}}
}}
==ZC3H12A==
==NEIL1==


* {{medline-title
* {{medline-title
|title=Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation.
|title=[[NEIL1]] stimulates neurogenesis and suppresses neuroinflammation after stress.
|date=12.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31786670
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175982
|full-text-url=https://sci-hub.do/10.1007/s00109-019-01853-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526462
}}
}}
* {{medline-title
* {{medline-title
|title=Prediction and characterization of human ageing-related proteins by using machine learning.
|title=Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation.
|date=06.03.2018
|date=09.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29511309
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26245904
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598976
}}
}}
==ZEB1==
==NEO1==


* {{medline-title
* {{medline-title
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|title=Neogenin-1 distinguishes between myeloid-biased and balanced [i]Hoxb5[/i]   mouse long-term hematopoietic stem cells.
|date=12.2018
|date=10.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754028
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911217
}}
}}
* {{medline-title
* {{medline-title
|title=Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating [[DNMT1]] via [[ZEB1]].
|title=Ionizing radiation reduces [[ADAM10]] expression in brain microvascular endothelial cells undergoing stress-induced senescence.
|date=16.02.2018
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29466247
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28437250
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425125
}}
}}
==ZEB2==
==NFATC1==


* {{medline-title
* {{medline-title
|title=miR-200b regulates cellular senescence and inflammatory responses by targeting [[ZEB2]] in pulmonary emphysema.
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
|date=12.2020
|date=02.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32070140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919
|full-text-url=https://sci-hub.do/10.1080/21691401.2020.1725029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA-145 induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by [[ZEB2]].
|title=Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS.
|date=05.2019
|date=25.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30479019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28545453
|full-text-url=https://sci-hub.do/10.1002/jcp.27521
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445414
}}
}}
==ZSCAN10==
==NFIB==


* {{medline-title
* {{medline-title
|title=RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells.
|title=Cell-type-specific expression of [[NFIX]] in the developing and adult cerebellum.
|date=10.10.2017
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020613
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878595
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639470
|full-text-url=https://sci-hub.do/10.1007/s00429-016-1340-8
}}
}}
* {{medline-title
* {{medline-title
|title=[[ZSCAN10]] expression corrects the genomic instability of iPSCs from aged donors.
|title=Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/[[NFIB]].
|date=09.2017
|date=03.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27545503
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843481
|full-text-url=https://sci-hub.do/10.1016/j.stem.2016.07.003
}}
}}
==AACS==
==NGFR==


* {{medline-title
* {{medline-title
|title=Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study.
|title=Evidence for changing nerve growth factor signalling mechanisms during development, maturation and ageing in the rat molar pulp.
|date=07.11.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33170149
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30099752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695390
|full-text-url=https://sci-hub.do/10.1111/iej.12997
}}
}}
==AANAT==
* {{medline-title
* {{medline-title
|title=Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis.
|title=A nutrigenomics approach for the study of anti-aging interventions: olive oil phenols and the modulation of gene and microRNA expression profiles in mouse brain.
|date=01.06.2019
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26695409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993622
|full-text-url=https://sci-hub.do/10.1007/s00394-015-1134-4
}}
}}
==ABCC9==
==NHLRC1==


* {{medline-title
* {{medline-title
|title=TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels.
|title=DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing.
|date=05.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30682540
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28254385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696921
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392537
}}
}}
==ABCE1==
* {{medline-title
* {{medline-title
|title=Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain.
|title=Loss of GABAergic cortical neurons underlies the neuropathology of Lafora disease.
|date=27.11.2018
|date=28.01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485811
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24472629
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354779
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917365
}}
}}
==ABCG1==
==NLRP1==


* {{medline-title
* {{medline-title
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.
|title=NADPH oxidase 2-mediated [[NLRP1]] inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro.
|date=08.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2019.01.025
}}
* {{medline-title
|title=Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24917880
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042684
}}
}}
==ABCG5==
==NLRP12==


* {{medline-title
* {{medline-title
|title=2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms.
|title=Persistent DNA damage-induced [[NLRP12]] improves hematopoietic stem cell function.
|date=01.04.2019
|date=21.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30939745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434992
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479705
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259522
}}
* {{medline-title
|title=Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26197995
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712099
}}
}}
==ABHD12==
==NLRX1==


* {{medline-title
* {{medline-title
|title=Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout [[ABHD12]] Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype.
|title=NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells.
|date=2019
|date=26.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31213981
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555221
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828065
}}
* {{medline-title
|title=The expression of [[NLRX1]] in C57BL/6 mice cochlear hair cells: Possible relation to aging- and neomycin-induced deafness.
|date=11.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26836140
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2015.11.053
}}
}}
==ABI3BP==
==NMB==


* {{medline-title
* {{medline-title
|title=Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing [[ABI3BP]] in gallbladder cancer cells.
|title=Characterizing Heterogeneity Bias in Cohort-Based Models.
|date=07.06.2019
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25851486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555920
|full-text-url=https://sci-hub.do/10.1007/s40273-015-0273-z
}}
* {{medline-title
|title=Asleep versus awake: does it matter?: Pediatric regional block complications by patient state: a report from the Pediatric Regional Anesthesia Network.
|date=07-08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24918334
|full-text-url=https://sci-hub.do/10.1097/AAP.0000000000000102
}}
}}
==ABL1==
==NME8==


* {{medline-title
* {{medline-title
|title=European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia.
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=04.2020
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32127639
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214240
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
* {{medline-title
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
}}
==ABLIM3==
==NMNAT1==


* {{medline-title
* {{medline-title
|title=Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization.
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|date=05.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29529016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
}}
}}
==ACAD10==
* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
Строка 3959: Строка 4613:
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==ACAD9==
==NMNAT2==


* {{medline-title
* {{medline-title
|title=Identification of a novel mitochondrial complex I assembly factor ACDH-12 in Caenorhabditis elegans.
|title=[[NMNAT2]]-mediated NAD  generation is essential for quality control of aged oocytes.
|date=05.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540318
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909324
|full-text-url=https://sci-hub.do/10.1016/j.mito.2018.02.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161
}}
}}
==ACADM==
* {{medline-title
* {{medline-title
|title=High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats.
|title=Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.
|date=07.2018
|date=03.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888352
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978465
|full-text-url=https://sci-hub.do/10.1016/j.jfma.2017.08.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640801
}}
}}
==ACAN==
==NMS==


* {{medline-title
* {{medline-title
|title=MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway.
|title=Uncontrolled Diabetes as an Associated Factor with Dynapenia in Adults Aged 50 Years or Older: Sex Differences.
|date=15.04.2019
|date=22.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30987676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665234
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243578
}}
}}
==ACAT2==
* {{medline-title
* {{medline-title
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
|title=Neonatal stress affects the aging trajectory of female rats on the endocrine, temperature, and ventilatory responses to hypoxia.
|date=15.12.2017
|date=01.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25652536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00418.2014
}}
}}
==ACD==
==NNMT==


* {{medline-title
* {{medline-title
|title=Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging.
|title=Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle.
|date=02.12.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792241
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889148
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469996
}}
}}
==ACMSD==
* {{medline-title
* {{medline-title
|title=De novo NAD  synthesis enhances mitochondrial function and improves health.
|title=Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy.
|date=11.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30356218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30192747
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191153
}}
}}
==ACO1==
==NONO==


* {{medline-title
* {{medline-title
|title=Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine.
|title=Physiological levels of thrombospondin-1 decrease NO-dependent vasodilation in coronary microvessels from aged rats.
|date=24.04.2019
|date=01.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30690072
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27199114
|full-text-url=https://sci-hub.do/10.1016/j.jep.2019.01.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345213
}}
}}
==ACSL5==
* {{medline-title
* {{medline-title
|title=Ageing sensitized by iPLA β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids.
|title=The effects of aging on the functional and structural properties of the rat basilar artery.
|date=12.2017
|date=01.06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888832
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24907295
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2017.09.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208653
}}
}}
==ACTA2==
==NOP10==


* {{medline-title
* {{medline-title
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|title=Pseudouridylation defect due to [i]DKC1[/i] and [i][[NOP10]][/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis.
|date=2018
|date=30.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554502
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334496
}}
}}
==ACTR3B==
* {{medline-title
* {{medline-title
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|date=2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
}}
}}
==ACVR1==
==NPAS2==


* {{medline-title
* {{medline-title
|title=Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=2019
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31998237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
==ADAMTS3==
* {{medline-title
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|title=Effects of circadian clock genes and environmental factors on cognitive aging in old adults in a Taiwanese population.
|date=01.2018
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412756
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421829
}}
}}
==ADAMTS9==
==NPTX2==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Evaluation of DNA methylation markers and their potential to predict human aging.
|date=02.2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26010003
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://sci-hub.do/10.1002/elps.201500137
}}
}}
==ADAR==
* {{medline-title
* {{medline-title
|title=Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis.
|title=Developing a DNA methylation assay for human age prediction in blood and bloodstain.
|date=09.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29986212
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25979242
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037660
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2015.05.007
}}
}}
==ADCK1==
==NPW==


* {{medline-title
* {{medline-title
|title=Functional analysis of Aarf domain-containing kinase 1 in Drosophila melanogaster.
|title=Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study.
|date=09.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175694
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32309980
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271681
|full-text-url=https://sci-hub.do/10.1037/pag0000468
}}
}}
==ADD2==
* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Neuropeptide W modulation of gastric vagal afferent mechanosensitivity: Impact of age and sex.
|date=04.07.2019
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26209028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1016/j.peptides.2015.07.011
}}
}}
==ADH1B==
==NR3C1==


* {{medline-title
* {{medline-title
|title=Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde.
|title=Glucocorticoid receptor ([[NR3C1]]) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians.
|date=02.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30553025
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2018.11.007
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.12.006
}}
* {{medline-title
|title=Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain.
|date=01.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28334178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093352
}}
}}
==ADIPOR1==
==NR4A2==


* {{medline-title
* {{medline-title
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|title=The NR4A nuclear receptors as potential targets for anti-aging interventions.
|date=2018
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25543265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2014.12.003
}}
* {{medline-title
|title=Comparative pathway and network analysis of brain transcriptome changes during adult aging and in Parkinson's disease.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25447234
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2014.11.002
}}
}}
==ADK==
==NRM==


* {{medline-title
* {{medline-title
|title=Deletion of pancreatic β-cell adenosine kinase improves glucose homeostasis in young mice and ameliorates streptozotocin-induced hyperglycaemia.
|title=Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation.
|date=07.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044530
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31445185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192097
}}
}}
==ADNP==
* {{medline-title
* {{medline-title
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|title=[[NRM]]T1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging.
|date=06.2019
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25843235
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457563
}}
}}
==ADNP2==
==NRXN1==


* {{medline-title
* {{medline-title
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|title=Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.
|date=06.2019
|date=01.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28013231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654756
}}
* {{medline-title
|title=Neurexin 1 ([[[[NRXN1]]]]) splice isoform expression during human neocortical development and aging.
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26216298
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731316
}}
}}
==ADORA2B==
==NRXN3==


* {{medline-title
* {{medline-title
|title=Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=12.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33131093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://sci-hub.do/10.1096/fj.202000939R
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==ADRA2A==
* {{medline-title
* {{medline-title
|title=α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway.
|title=Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.
|date=2020
|date=01.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33116632
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28013231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574911
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654756
}}
}}
==ADRA2B==
==NTF4==


* {{medline-title
* {{medline-title
|title=Aging and the Combined effects of [[ADRA2B]] and CB1 deletions on Affective Working Memory.
|title=Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles.
|date=11.03.2019
|date=13.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30858399
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28654072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608439
}}
}}
==ADRM1==
* {{medline-title
* {{medline-title
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
|title=Enhancement of aging rat laryngeal muscles with endogenous growth factor treatment.
|date=01.08.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27207784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886166
}}
}}
==AGAP2==
==OAT==


* {{medline-title
* {{medline-title
|title=Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating [[AGAP2]].
|title=Opioid agonist treatment reduces losses in quality of life and quality-adjusted life expectancy in heroin users: Evidence from real world data.
|date=05.08.2019
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386624
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710058
|full-text-url=https://sci-hub.do/10.1016/j.drugalcdep.2019.05.003
}}
}}
==AHCY==
* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats.
|date=11.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712161
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00663-x
}}
}}
==AIDA==
==OGA==


* {{medline-title
* {{medline-title
|title=Identification of Postharvest Senescence Regulators Through Map-Based Cloning Using Detached Arabidopsis Inflorescences as a Model Tissue.
|title=NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase.
|date=2018
|date=19.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392668
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31747588
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-7672-0_17
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.10.053
}}
}}
==AIF1==
* {{medline-title
* {{medline-title
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|title=Aging leads to elevation of O-GlcNAcylation and disruption of mitochondrial homeostasis in retina.
|date=06.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24987494
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060167
}}
}}
==AKAP12==
==PAPSS2==


* {{medline-title
* {{medline-title
|title=A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter.
|title=Autosomal recessive brachyolmia: early radiological findings.
|date=05.2018
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29314444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27544198
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918158
|full-text-url=https://sci-hub.do/10.1007/s00256-016-2458-8
}}
* {{medline-title
|title=Gene Expression Differences Between Offspring of Long-Lived Individuals and Controls in Candidate Longevity Regions: Evidence for [[PAPSS2]] as a Longevity Gene.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26896383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018562
}}
}}
==AKAP17A==
==PAX5==


* {{medline-title
* {{medline-title
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|title=Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low [[PAX5]].
|date=10.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29425852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
|full-text-url=https://sci-hub.do/10.1016/j.clim.2018.02.003
}}
}}
==AKT2==
* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Developmental expression of B cell molecules in equine lymphoid tissues.
|date=02.2019
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28063478
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267323
}}
}}
==AKT3==
==PAX6==


* {{medline-title
* {{medline-title
|title=Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma.
|title=Pbx1 is required for adult subventricular zone neurogenesis.
|date=10.2018
|date=01.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27226325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958316
}}
}}
==AKTIP==
* {{medline-title
* {{medline-title
|title=Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits.
|title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.
|date=08.2018
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29635765
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052474
|full-text-url=https://sci-hub.do/10.1134/S0006297915030062
}}
}}
==ALAS1==
==PBX1==


* {{medline-title
* {{medline-title
|title=Heterozygous disruption of [[ALAS1]] in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver.
|title=Internalization of the TAT-[[PBX1]] fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence.
|date=08.12.2020
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33307066
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436118
|full-text-url=https://sci-hub.do/10.1016/j.abb.2020.108721
|full-text-url=https://sci-hub.do/10.1007/s10529-020-02909-x
}}
}}
==ALDH3A1==
* {{medline-title
* {{medline-title
|title=Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs).
|title=Pbx1 is required for adult subventricular zone neurogenesis.
|date=13.02.2019
|date=01.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27226325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958316
}}
}}
==ALDOA==
==PCDH10==


* {{medline-title
* {{medline-title
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|date=06.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
}}
}}
==ALK==
* {{medline-title
* {{medline-title
|title=Catalog of Lung Cancer Gene Mutations Among Chinese Patients.
|title=[[PCDH10]], a novel p53 transcriptional target in regulating cell migration.
|date=2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850378
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25590240
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615063
}}
}}
==ALKBH1==
==PDCD4==


* {{medline-title
* {{medline-title
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|title=Petal abscission in roses is associated with the activation of a truncated version of the animal [[PDCD4]] homologue, RbPCD1.
|date=2018
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521226
 
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2019.110242
}}
}}
==ALKBH2==
* {{medline-title
* {{medline-title
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|title=[[PDCD4]] Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30687637
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334536
}}
}}
==ALOX12==
==PDE10A==


* {{medline-title
* {{medline-title
|title=Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer.
|title=Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain.
|date=15.05.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32265301
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175000
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242692
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732030
}}
}}
==ALOX5==
* {{medline-title
* {{medline-title
|title=Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme.
|title=Patterns of age related changes for phosphodiesterase type-10A in comparison with dopamine D  receptors and sub-cortical volumes in the human basal ganglia: A PET study with  F-MNI-659 and  C-raclopride with correction for partial volume effect.
|date=01.01.2020
|date=15.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642348
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28254508
|full-text-url=https://sci-hub.do/10.1089/ars.2019.7751
|full-text-url=https://sci-hub.do/10.1016/j.neuroimage.2017.02.047
}}
}}
==AMFR==
==PDE1A==


* {{medline-title
* {{medline-title
|title=Mice heterozygous for the Cdh23/Ahl1 mutation show age-related deficits in auditory temporal processing.
|title=Phosphodiesterase 1 regulation is a key mechanism in vascular aging.
|date=09.2019
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26464516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732241
|full-text-url=https://sci-hub.do/10.1042/CS20140753
}}
}}
==AMHR2==
* {{medline-title
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|title=Cyclic nucleotide phosphodiesterase 1 and vascular aging.
|date=03.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26374857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610264
}}
}}
==AMPH==
==PDE1C==


* {{medline-title
* {{medline-title
|title=Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood.
|title=Phosphodiesterase 1 regulation is a key mechanism in vascular aging.
|date=01.09.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29792867
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26464516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026035
|full-text-url=https://sci-hub.do/10.1042/CS20140753
}}
}}
==ANG==
* {{medline-title
* {{medline-title
|title=Age-related differences in the cutaneous vascular response to exogenous angiotensin II.
|title=Cyclic nucleotide phosphodiesterase 1 and vascular aging.
|date=01.03.2019
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30499715
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26374857
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00509.2018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610264
}}
}}
==ANGPT2==
==PDE4B==


* {{medline-title
* {{medline-title
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|title=Phosphodiesterase-4B as a Therapeutic Target for Cognitive Impairment and Obesity-Related Metabolic Diseases.
|date=14.11.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28956331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
|full-text-url=https://sci-hub.do/10.1007/978-3-319-58811-7_5
}}
}}
==ANGPTL4==
* {{medline-title
* {{medline-title
|title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells.
|title=The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation.
|date=05.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28438557
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2017.04.015
}}
}}
==ANK2==
==PDGFB==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Skin-resident stem cells and wound healing.
|date=04.07.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28539548
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.2177/jsci.40.1
}}
}}
==ANK3==
* {{medline-title
* {{medline-title
|title=Age-related atrophy of cortical thickness and genetic effect of [[ANK3]] gene in first episode MDD patients.
|title=The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease.
|date=26.08.2020
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32911427
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26092102
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490581
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2015.06.008
}}
}}
==ANKS1B==
==PDGFRB==


* {{medline-title
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|date=01.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
}}
}}
==ANPEP==
* {{medline-title
* {{medline-title
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity.
|title=Expansion of the phenotype of Kosaki overgrowth syndrome.
|date=25.06.2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28639748
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.38310
}}
}}
==ANXA1==
==PDK2==


* {{medline-title
* {{medline-title
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging.
|title=Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training.
|date=26.10.2018
|date=01.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27221120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967149
}}
}}
==AOX1==
* {{medline-title
* {{medline-title
|title=N1-Methylnicotinamide: An Anti-Ovarian Aging Hormetin?
|title=Effects of Exercise Training on Regulation of Skeletal Muscle Glucose Metabolism in Elderly Men.
|date=09.2020
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32711159
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25991826
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101131
|full-text-url=https://sci-hub.do/10.1093/gerona/glv012
}}
}}
==AP2B1==
==PDK4==


* {{medline-title
* {{medline-title
|title=Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice.
|title=Putrescine delays postovulatory aging of mouse oocytes by upregulating [[PDK4]] expression and improving mitochondrial activity.
|date=20.12.2019
|date=16.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31860870
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326651
}}
}}
==APLNR==
* {{medline-title
* {{medline-title
|title=Endothelial [[APLNR]] regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.
|title=Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training.
|date=13.09.2017
|date=01.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27221120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967149
}}
}}
==APLP2==
==PDX1==


* {{medline-title
* {{medline-title
|title=Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex.
|title=Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of [[INS]]-1 cells through Pim-1.
|date=06.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27049278
|full-text-url=https://sci-hub.do/10.1007/s11064-018-2669-6
}}
==APOA1==


* {{medline-title
|title=Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29623474
|full-text-url=https://sci-hub.do/10.1007/s10534-018-0101-y
}}
}}
==APOBEC1==
* {{medline-title
* {{medline-title
|title=Loss of [[APOBEC1]] RNA-editing function in microglia exacerbates age-related CNS pathophysiology.
|title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.
|date=12.12.2017
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167375
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740644
|full-text-url=https://sci-hub.do/10.1134/S0006297915030062
}}
}}
==APOC1==
==PENK==


* {{medline-title
* {{medline-title
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|title=Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study.
|date=08.10.2018
|date=09.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26861258
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746895
}}
}}
==APOC3==
* {{medline-title
* {{medline-title
|title=Positional Obstructive Sleep Apnea Syndrome in Elderly Patients.
|title=Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs.
|date=10.02.2020
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32050596
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24789080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082572
}}
}}
==APPL1==
==PES1==


* {{medline-title
* {{medline-title
|title=Insulin and adipokine signaling and their cross-regulation in postmortem human brain.
|title=Transcription factor RD26 is a key regulator of metabolic reprogramming during dark-induced senescence.
|date=12.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31539648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960343
|full-text-url=https://sci-hub.do/10.1111/nph.15127
}}
}}
==AQP2==
* {{medline-title
* {{medline-title
|title=A bell-shaped pattern of urinary aquaporin-2-bearing extracellular vesicle release in an experimental model of nephronophthisis.
|title=The Plastoglobule-Localized Metallopeptidase PGM48 Is a Positive Regulator of Senescence in Arabidopsis thaliana.
|date=05.2019
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074077
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27895226
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240743
}}
}}
==AQP4==
==PFKFB3==


* {{medline-title
* {{medline-title
|title=Overexpression of Slit2 improves function of the paravascular pathway in the aging mouse brain.
|title=DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system.
|date=10.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30085336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108881
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871568
}}
}}
==AQP5==
* {{medline-title
* {{medline-title
|title=Submandibular gland-specific inflammaging-induced hyposalivation in the male senescence-accelerated mouse prone -1 line (SAM-P1).
|title=Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity.
|date=08.2019
|date=15.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25814669
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09797-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432272
}}
}}
==ARHGAP18==
==PGD==


* {{medline-title
* {{medline-title
|title=Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma
|title=Primary Care for the Elderly Bereaved: Recommendations for Medical Education.
|date=18.11.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29500657
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863019
|full-text-url=https://sci-hub.do/10.1007/s10880-018-9556-9
}}
}}
==ARID1B==
* {{medline-title
* {{medline-title
|title=A 69-year-old woman with Coffin-Siris syndrome.
|title=High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles.
|date=08.2018
|date=01.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055038
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29303233
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.38844
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844656
}}
}}
==ARID5A==
==PGR==


* {{medline-title
* {{medline-title
|title=Differentially regulated gene expression in quiescence versus senescence and identification of [[ARID5A]] as a quiescence associated marker.
|title=Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain.
|date=05.2018
|date=01.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29044508
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28334178
|full-text-url=https://sci-hub.do/10.1002/jcp.26227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093352
}}
}}
==ARL13B==
* {{medline-title
* {{medline-title
|title=[[ARL13B]], a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments.
|title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus.
|date=20.02.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460
}}
}}
==ARNTL==
==PHB2==


* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=Prohibitin-2 is a novel regulator of p21  induced by depletion of γ-glutamylcyclotransferase.
|date=21.11.2018
|date=29.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29307834
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.029
}}
}}
==ARNTL2==
* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor.
|date=21.11.2018
|date=12.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28017329
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235968
}}
}}
==ARRB2==
==PI4KB==


* {{medline-title
* {{medline-title
|title=Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity.
|title=Differential DNA Methylation in Relation to Age and Health Risks of Obesity.
|date=12.2019
|date=24.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26213922
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581172
}}
}}
==ARSA==
* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=06.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
}}
==ASB3==
==PIEZO1==


* {{medline-title
* {{medline-title
|title=Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.
|title=Niche stiffness underlies the ageing of central nervous system progenitor cells.
|date=02.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585438
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31413369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818258
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025879
}}
}}
==ASB7==
* {{medline-title
 
|title=On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, [[PIEZO1]], and Gardos Channels.
* {{medline-title
|date=2017
|title=[[ASB7]] Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation.
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29311949
|date=2020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732905
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33251222
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674779
}}
}}
==ASIP==
==PIK3R2==


* {{medline-title
* {{medline-title
|title=Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation.
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|date=10.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222197
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|full-text-url=https://sci-hub.do/10.1111/ics.12494
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
}}
}}
==ASMT==
* {{medline-title
* {{medline-title
|title=The influence of ageing on the extrapineal melatonin synthetic pathway.
|title=Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons.
|date=09.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29906492
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26487704
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.06.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757025
}}
}}
==ASPA==
==PLA2G6==


* {{medline-title
* {{medline-title
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|title=Mutations in the Drosophila homolog of human [[PLA2G6]] give rise to age-dependent loss of psychomotor activity and neurodegeneration.
|date=04.2018
|date=13.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29440694
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811537
}}
}}
==ATF2==
* {{medline-title
* {{medline-title
|title=Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium.
|title=iPLA2β knockout mouse, a genetic model for progressive human motor disorders, develops age-related neuropathology.
|date=01.04.2018
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360953
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24919816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915954
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364003
}}
}}
==ATF3==
==PLA2R1==


* {{medline-title
* {{medline-title
|title=[[ATF3]] represses [[PINK1]] gene transcription in lung epithelial cells to control mitochondrial homeostasis.
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
|date=04.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29363258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922
}}
}}
==ATF7==
* {{medline-title
* {{medline-title
|title=Stress-induced and [[ATF7]]-dependent epigenetic change influences cellular senescence.
|title=[[PLA2R1]]: expression and function in cancer.
|date=09.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31294895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24667060
|full-text-url=https://sci-hub.do/10.1111/gtc.12713
|full-text-url=https://sci-hub.do/10.1016/j.bbcan.2014.03.003
}}
}}
==ATG10==
==PLD3==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=10.2019
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
==ATG16L1==
* {{medline-title
* {{medline-title
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=04.2019
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
}}
==ATG4B==
==PLK4==


* {{medline-title
* {{medline-title
|title=Impaired autophagic activity and [[ATG4B]] deficiency are associated with increased endoplasmic reticulum stress-induced lung injury.
|title=A novel lncRNA [[PLK4]] up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence.
|date=27.08.2018
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30147026
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32243714
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205816
}}
* {{medline-title
|title=Differential expression of AURKA/[[PLK4]] in quiescence and senescence of osteosarcoma U2OS cells.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32200684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217361
}}
}}
==ATG4D==
==POLD3==


* {{medline-title
* {{medline-title
|title=Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats.
|title=[[POLD3]] Is Haploinsufficient for DNA Replication in Mice.
|date=17.07.2019
|date=01.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242723
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27524497
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b02567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029548
}}
}}
==ATP1A2==
* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=[[POLD1]]: Central mediator of DNA replication and repair, and implication in cancer and other pathologies.
|date=04.07.2019
|date=15.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27320729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969162
}}
}}
==ATP2B1==
==POLG2==


* {{medline-title
* {{medline-title
|title=Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries.
|title=An N-Ethyl-N-Nitrosourea (ENU)-Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice.
|date=10.2017
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28795531
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30395686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446808
}}
}}
==ATP6V0C==
* {{medline-title
* {{medline-title
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=07.12.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
}}
==ATP6V1E1==
==PPARD==


* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=[[PP[[AR]]D]]  294C overrepresentation in general and long-lived population in China Bama longevity area and unique relationships between [[PP[[AR]]D]] 294T/C polymorphism and serum lipid profiles.
|date=07.2018
|date=07.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873088
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356147
}}
}}
==ATXN1==
* {{medline-title
|title=[Genotype and allele frequencies of U[[CP]] and PP[[AR]] gene families in residents of besieged Leningrad and in the control group].
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826986


* {{medline-title
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
}}
==ATXN3==
==PPM1D==


* {{medline-title
* {{medline-title
|title=Rescue of [[ATXN3]] neuronal toxicity in [i]Caenorhabditis[/i][i]elegans[/i] by chemical modification of endoplasmic reticulum stress.
|title=Detectible mosaic truncating [[PPM1D]] mutations, age and breast cancer risk.
|date=19.12.2017
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29061563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30850729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769603
|full-text-url=https://sci-hub.do/10.1038/s10038-019-0589-1
}}
}}
==AXL==
* {{medline-title
* {{medline-title
|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells.
|title=Age-related remodelling of oesophageal epithelia by mutated cancer drivers.
|date=01.2020
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30602793
|full-text-url=https://sci-hub.do/10.1111/pcmr.12811
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0811-x
}}
}}
==BACH2==
==PPY==


* {{medline-title
* {{medline-title
|title=Age-related changes in the [[BACH2]] and [[PRDM1]] genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.
|title=Delta Cell Hyperplasia in Adult Goto-Kakizaki ([[GK]]/MolTac) Diabetic Rats.
|date=17.01.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654767
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26236746
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506919
}}
}}
==BAG3==
* {{medline-title
* {{medline-title
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
|title=Blood Protein Markers of Neocortical Amyloid-β Burden: A Candidate Study Using SOMAscan Technology.
|date=03.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25881911
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923714
}}
}}
==BANF1==
==PRDM16==


* {{medline-title
* {{medline-title
|title=An additional case of Néstor-Guillermo progeria syndrome diagnosed in early childhood.
|title=Assessment of the Aging of the Brown Adipose Tissue by  F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna .
|date=10.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32783369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116163
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.61777
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079616
}}
}}
==BARD1==
* {{medline-title
* {{medline-title
|title=BRCA1 and [[BARD1]] mediate apoptotic resistance but not longevity upon mitochondrial stress in [i]Caenorhabditis elegans[/i].
|title=Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5'-flanking region of [[PRDM16]] gene associated with lean body mass.
|date=12.2018
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30366941
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24863034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326941
}}
}}
==BAZ1A==
==PRF1==


* {{medline-title
* {{medline-title
|title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells.
|title=Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons.
|date=15.07.2019
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26487704
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757025
}}
}}
==BAZ2B==
* {{medline-title
* {{medline-title
|title=Two conserved epigenetic regulators prevent healthy ageing.
|title=Gene expression markers of age-related inflammation in two human cohorts.
|date=03.2020
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32103178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26087330
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2037-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600657
}}
}}
==BBS5==
==PRMT5==


* {{medline-title
* {{medline-title
|title=Progressive Characterization of Visual Phenotype in Bardet-Biedl Syndrome Mutant Mice.
|title=Regenerating muscle with arginine methylation.
|date=01.03.2019
|date=27.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30901771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28301308
|full-text-url=https://sci-hub.do/10.1167/iovs.18-25210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501374
}}
}}
==BCAS1==
* {{medline-title
* {{medline-title
|title=Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs).
|title=Simultaneous ablation of prmt-1 and prmt-5 abolishes asymmetric and symmetric arginine dimethylations in Caenorhabditis elegans.
|date=13.02.2019
|date=01.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28158808
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382415
|full-text-url=https://sci-hub.do/10.1093/jb/mvw101
}}
}}
==BCL11B==
==PRMT7==


* {{medline-title
* {{medline-title
|title=Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells.
|title=Regenerating muscle with arginine methylation.
|date=05.2018
|date=27.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28301308
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501374
}}
}}
==BCL2L1==
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=[[PRMT7]] Preserves Satellite Cell Regenerative Capacity.
|date=09.2017
|date=16.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26854227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2016.01.022
}}
}}
==BCL2L11==
==PRMT8==


* {{medline-title
* {{medline-title
|title=miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence.
|title=Arginine Methyltransferase [[PRMT8]] Provides Cellular Stress Tolerance in Aging Motoneurons.
|date=01.2020
|date=29.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054395
|full-text-url=https://sci-hub.do/10.1002/jcb.28862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113905
}}
}}
==BHLHE40==
* {{medline-title
* {{medline-title
|title=Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1.
|title=Novel Protein Arginine Methyltransferase 8 Isoform Is Essential for Cell Proliferation.
|date=07.2020
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32360904
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26851891
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105689
|full-text-url=https://sci-hub.do/10.1002/jcb.25508
}}
}}
==BMP6==
==PRNP==


* {{medline-title
* {{medline-title
|title=Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology.
|title=Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS.
|date=06.11.2018
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352848
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32516343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233090
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282622
}}
* {{medline-title
|title=AGE AND REPEATED BIOPSY INFLUENCE ANTEMORTEM PRP(CWD) TESTING IN MULE DEER (ODOCOILEUS HEMIONUS) IN COLORADO, USA.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26251986
|full-text-url=https://sci-hub.do/10.7589/2014-12-284
}}
}}
==BMP7==
==PTBP1==


* {{medline-title
* {{medline-title
|title=Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting [[BMP7]].
|title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence.
|date=11.12.2019
|date=11.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31829291
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934
}}
}}
==BMPR1B==
* {{medline-title
* {{medline-title
|title=Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes.
|title=[[PTBP1]]-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.
|date=12.2018
|date=09.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503129
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990503
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.08.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048363
}}
}}
==BMPR2==
==PTH1R==


* {{medline-title
* {{medline-title
|title=Centenarians Overexpress Pluripotency-Related Genes.
|title=Bone-remodeling transcript levels are independent of perching in end-of-lay white leghorn chickens.
|date=16.08.2019
|date=23.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25625518
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346857
}}
}}
==BNC1==
* {{medline-title
* {{medline-title
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|title=Variation in the [[[[PTH]]2R]] gene is associated with age-related degenerative changes in the lumbar spine.
|date=22.01.2020
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24378925
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
|full-text-url=https://sci-hub.do/10.1007/s00774-013-0550-x
}}
}}
==BOC==
==PUM2==


* {{medline-title
* {{medline-title
|title=Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations.
|title=PUMILIO hyperactivity drives premature aging of [i]Norad[/i]-deficient mice.
|date=01.05.2020
|date=08.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32140711
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30735131
|full-text-url=https://sci-hub.do/10.1093/jn/nxaa031
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407921
}}
}}
==BRD2==
* {{medline-title
* {{medline-title
|title=Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice.
|title=The RNA-Binding Protein [[PUM2]] Impairs Mitochondrial Dynamics and Mitophagy During Aging.
|date=2020
|date=21.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32559200
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30642763
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304595
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396316
}}
}}
==BRD3==
==PYCR1==


* {{medline-title
* {{medline-title
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke.
|title=A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals [[POSTN]] As a New Element in Proline Metabolic Disorder.
|date=07.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574417
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284769
}}
}}
==BTC==
* {{medline-title
* {{medline-title
|title=Behavioral tagging and capture: long-term memory decline in middle-aged rats.
|title=Sublethal endoplasmic reticulum stress caused by the mutation of immunoglobulin heavy chain-binding protein induces the synthesis of a mitochondrial protein, pyrroline-5-carboxylate reductase 1.
|date=07.2018
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29609080
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27796797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964067
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225059
}}
}}
==BTG1==
==RAC1==


* {{medline-title
* {{medline-title
|title=Tumor cell escape from therapy-induced senescence.
|title=Reactive oxygen species: The good, the bad, and the enigma.
|date=04.2019
|date=07-09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576620
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27308352
|full-text-url=https://sci-hub.do/10.1016/j.bcp.2018.12.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904994
}}
* {{medline-title
|title=NADPH oxidase-derived production of reactive oxygen species is involved in learning and memory impairments in 16-month-old female rats.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26058943
|full-text-url=https://sci-hub.do/10.3892/mmr.2015.3894
}}
}}
==C2CD2==
==RAF1==


* {{medline-title
* {{medline-title
|title=Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort.
|title=Circular [i]ANRIL[/i] isoforms switch from repressors to activators of [i]p15/CDKN2B[/i] expression during [[RAF1]] oncogene-induced senescence.
|date=20.11.2017
|date=29.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29158487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32862732
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696534
|full-text-url=https://sci-hub.do/10.1080/15476286.2020.1812910
}}
}}
==CA12==
* {{medline-title
* {{medline-title
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|title=MSK1 triggers the expression of the INK4AB/ARF locus in oncogene-induced senescence.
|date=26.06.2018
|date=01.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27385346
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007092
}}
}}
==CABLES1==
==RAG1==


* {{medline-title
* {{medline-title
|title=[[CABLES1]] Deficiency Impairs Quiescence and Stress Responses of Hematopoietic Stem Cells in Intrinsic and Extrinsic Manners.
|title=T cell senescence accelerates Angiotensin II-induced target organ damage.
|date=13.08.2019
|date=12.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32049355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700604
|full-text-url=https://sci-hub.do/10.1093/cvr/cvaa032
}}
}}
==CACNA1B==
* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Aged murine hematopoietic stem cells drive aging-associated immune remodeling.
|date=10.2019
|date=09.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137572
}}
}}
==CACNA1S==
==RAG2==


* {{medline-title
* {{medline-title
|title=Increased calcium channel in the lamina propria of aging rat.
|title=Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation.
|date=31.10.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31682233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834399
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387685
}}
}}
==CALR==
* {{medline-title
* {{medline-title
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender.
|title=Both retention and recirculation contribute to long-lived regulatory T-cell accumulation in the thymus.
|date=10.2017
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24894919
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177035
}}
}}
==CAMSAP1==
==RECQL5==


* {{medline-title
* {{medline-title
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|title=[[RECQL5]] has unique strand annealing properties relative to the other human RecQ helicase proteins.
|date=2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26717024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903426
}}
}}
==CAP2==
* {{medline-title
* {{medline-title
|title=Targeting MRTF/[[SRF]] in [[CAP2]]-dependent dilated cardiomyopathy delays disease onset.
|title=Senescence induced by [[RECQL4]] dysfunction contributes to Rothmund-Thomson syndrome features in mice.
|date=21.03.2019
|date=15.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30762586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24832598
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047874
}}
}}
==CAPRIN1==
==RELA==


* {{medline-title
* {{medline-title
|title=Reduced Levels of the Synaptic Functional Regulator FMRP in Dentate Gyrus of the Aging Sprague-Dawley Rat.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=2017
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29218006
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703695
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==CARF==
* {{medline-title
* {{medline-title
|title=Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
|title=The Inflammatory Transcription Factors NFκB, [[STAT1]] and [[STAT3]] Drive Age-Associated Transcriptional Changes in the Human Kidney.
|date=22.05.2020
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31112603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26678048
|full-text-url=https://sci-hub.do/10.1093/gerona/glz077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682820
}}
}}
==CARM1==
==RIPK2==


* {{medline-title
* {{medline-title
|title=[[CARM1]] regulates senescence during airway epithelial cell injury in COPD pathogenesis.
|title=RIP kinases as modulators of inflammation and immunity.
|date=01.11.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31461302
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615
|full-text-url=https://sci-hub.do/10.1152/ajplung.00441.2018
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x
}}
}}
==CASK==
* {{medline-title
* {{medline-title
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats.
|title=Molecular modeling in the age of clinical genomics, the enterprise of the next generation.
|date=01.2018
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28204942
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529140
}}
}}
==CASP3==
==RPIA==


* {{medline-title
* {{medline-title
|title=Does cartilage ERα overexpression correlate with osteoarthritic chondrosenescence? Indications from [i]Labisia pumila[/i] OA mitigation.
|title=Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming.
|date=09.2019
|date=20.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31502578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31433975
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716532
}}
}}
==CASS4==
* {{medline-title
* {{medline-title
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|title=Ribose-5-phosphate isomerase A regulates hepatocarcinogenesis via PP2A and ERK signaling.
|date=2017
|date=01.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25429733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
|full-text-url=https://sci-hub.do/10.1002/ijc.29361
}}
}}
==CAV1==
==RPS6==


* {{medline-title
* {{medline-title
|title=Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine.
|title=Regulation of Amino Acid Transporters and Sensors in Response to a High protein Diet: A Randomized Controlled Trial in Elderly Men.
|date=24.04.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30690072
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30932134
|full-text-url=https://sci-hub.do/10.1016/j.jep.2019.01.019
|full-text-url=https://sci-hub.do/10.1007/s12603-019-1171-4
}}
}}
==CBX3==
* {{medline-title
* {{medline-title
|title=Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development.
|title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107.
|date=24.09.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32979540
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052
|full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115659
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016
}}
}}
==CBX4==
==RRM1==


* {{medline-title
* {{medline-title
|title=Maintenance of Nucleolar Homeostasis by [[CBX4]] Alleviates Senescence and Osteoarthritis.
|title=α-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1.
|date=26.03.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30917318
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977294
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.02.088
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612645
}}
}}
==CBX8==
* {{medline-title
* {{medline-title
|title=[[PIM1]]-catalyzed [[CBX8]] phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast.
|title=GBM-associated mutations and altered protein expression are more common in young patients.
|date=27.06.2018
|date=25.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29763603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.05.070
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491
}}
}}
==CCAR2==
==RTEL1==


* {{medline-title
* {{medline-title
|title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans.
|title=Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants.
|date=10.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31444995
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826144
}}
}}
==CCDC88A==
* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Genome-wide association study of telomere length among South Asians identifies a second [[RTEL1]] association signal.
|date=02.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29151059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749304
}}
}}
==CCL13==
==S100A12==


* {{medline-title
* {{medline-title
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|title=Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model.
|date=07.2019
|date=06.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991479
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078409
}}
}}
==CCL18==
* {{medline-title
* {{medline-title
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|title=Evaluation of serum biochemical marker concentrations and survival time in dogs with protein-losing enteropathy.
|date=07.2019
|date=01.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25517330
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
|full-text-url=https://sci-hub.do/10.2460/javma.246.1.91
}}
}}
==CCL19==
==S100A4==


* {{medline-title
* {{medline-title
|title=Age-Related Gliosis Promotes Central Nervous System Lymphoma through [[CCL19]]-Mediated Tumor Cell Retention.
|title=Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice.
|date=16.09.2019
|date=15.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31526758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678243
|full-text-url=https://sci-hub.do/10.1016/j.ccell.2019.08.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894395
}}
}}
==CCL28==
* {{medline-title
* {{medline-title
|title=Age-related chemokine alterations affect IgA secretion and gut immunity in female mice.
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|date=10.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32277312
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09877-9
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
}}
}}
==CCN4==
==S1PR3==


* {{medline-title
* {{medline-title
|title=CCN proteins as potential actionable targets in scleroderma.
|title=Sexual dimorphism of metabolic and vascular dysfunction in aged mice and those lacking the sphingosine 1-phosphate receptor 3.
|date=01.2019
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30329180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28943478
|full-text-url=https://sci-hub.do/10.1111/exd.13806
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.013
}}
}}
==CCNA1==
* {{medline-title
* {{medline-title
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
|title=Impact of Age and Polytherapy on Fingolimod Induced Bradycardia: a Preclinical Study.
|date=02.10.2017
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28150133
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654
|full-text-url=https://sci-hub.do/10.1007/s11481-017-9727-8
}}
}}
==CCNA2==
==SAA1==


* {{medline-title
* {{medline-title
|title=Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan.
|title=Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells.
|date=31.03.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884545
}}
}}
==CCND1==
* {{medline-title
|title=Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846716
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573208
}}
==SALL1==


* {{medline-title
* {{medline-title
|title=Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells.
|title=[[SALL1]] functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex.
|date=09.2020
|date=06.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592933
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29625565
|full-text-url=https://sci-hub.do/10.1016/j.archoralbio.2020.104819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889587
}}
* {{medline-title
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
}}
}}
==CCND2==
==SCGN==


* {{medline-title
* {{medline-title
|title=Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma.
|title=Detection and evaluation of DNA methylation markers found at [[SCGN]] and [[KLF14]] loci to estimate human age.
|date=10.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854399
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135677
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011
}}
* {{medline-title
|title=DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28254385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392537
}}
}}
==CCND3==
==SCN2B==


* {{medline-title
* {{medline-title
|title=The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells.
|title=MicroRNA‑449a regulates the progression of brain aging by targeting [[SCN2B]] in SAMP8 mice.
|date=29.07.2020
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32727592
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32124967
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392710
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053848
}}
}}
==CCR3==
* {{medline-title
* {{medline-title
|title=Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro.
|title=Sodium Channel Voltage-Gated Beta 2 Plays a Vital Role in Brain Aging Associated with Synaptic Plasticity and Expression of COX5A and FGF-2.
|date=04.02.2020
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32033185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25575679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036885
|full-text-url=https://sci-hub.do/10.1007/s12035-014-9048-3
}}
}}
==CD2==
==SCN5A==


* {{medline-title
* {{medline-title
|title=Adaptive NKG2C CD57  Natural Killer Cell and Tim-3 Expression During Viral Infections.
|title=[Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug].
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731749
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30175758
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919961
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00114
}}
}}
==CD209==
* {{medline-title
|title=Sequencing of [[SCN5A]] identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177904
}}
==SDC4==


* {{medline-title
* {{medline-title
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|date=03.2018
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
}}
}}
==CD226==
* {{medline-title
* {{medline-title
|title=T-cell Immunoglobulin and ITIM Domain Contributes to CD8  T-cell Immunosenescence.
|title=Metabolism and successful aging: Polymorphic variation of syndecan-4 ([[SDC4]]) gene associate with longevity and lipid profile in healthy elderly Italian subjects.
|date=04.2018
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29349889
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26254886
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847879
|full-text-url=https://sci-hub.do/10.1016/j.mad.2015.08.003
}}
}}
==CD2AP==
==SDHA==


* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=Accumulation of electrophilic aldehydes during postovulatory aging of mouse oocytes causes reduced fertility, oxidative stress, and apoptosis.
|date=28.03.2018
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25505195
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://sci-hub.do/10.1095/biolreprod.114.122820
}}
}}
==CD48==
* {{medline-title
* {{medline-title
|title=Genetic overexpression of [[COMP]]-Ang1 impairs BM microenvironment and induces senescence of BM HSCs.
|title=Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone.
|date=15.05.2018
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604278
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24760536
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.210
|full-text-url=https://sci-hub.do/10.1530/EJE-14-0006
}}
}}
==CD55==
==SDHB==


* {{medline-title
* {{medline-title
|title=Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia.
|title=Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study.
|date=15.11.2018
|date=12.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32059608
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074517
}}
}}
==CD59==
* {{medline-title
* {{medline-title
|title=Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria.
|title=Mitochondrial bioenergetics and disease in Caenorhabditis elegans.
|date=2019
|date=01.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25553447
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529780
|full-text-url=https://sci-hub.do/10.2741/4305
}}
}}
==CD72==
==SESN2==


* {{medline-title
* {{medline-title
|title=Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation.
|title=Copy Number Alterations in Papillary Thyroid Carcinomas: Does Loss of [i][[SESN2]][/i] Have a Role in Age-related Different Prognoses?
|date=2019
|date=09-10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930899
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32859642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428705
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472442
}}
}}
==CD82==
* {{medline-title
* {{medline-title
|title=Cell-surface phenotyping identifies [[CD36]] and CD97 as novel markers of fibroblast quiescence in lung fibrosis.
|title=Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea.
|date=01.11.2018
|date=11.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28818524
|full-text-url=https://sci-hub.do/10.1152/ajplung.00439.2017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605466
}}
}}
==CDC20==
==SESN3==


* {{medline-title
* {{medline-title
|title=Premature aging syndrome showing random chromosome number instabilities with [[CDC20]] mutation.
|title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging.
|date=11.2020
|date=25.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33094908
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681047
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052
}}
}}
==CDC25A==
* {{medline-title
* {{medline-title
|title=Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage.
|title=Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration.
|date=10.10.2020
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28430387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600899
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650945
}}
}}
==CDC6==
==SF3B1==


* {{medline-title
* {{medline-title
|title=A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.
|title=Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis.
|date=10.01.2018
|date=03.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29321003
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25732814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763532
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542313
}}
}}
==CDC73==
* {{medline-title
* {{medline-title
|title=Down-regulation of cancer-associated gene [[CDC73]] contributes to cellular senescence.
|title=Splicing factor 3B1 hypomethylation is associated with altered [[SF3B1]] transcript expression in older humans.
|date=23.05.2018
|date=01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29621547
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24463145
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.228
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985527
}}
}}
==CDH1==
==SFRP2==


* {{medline-title
* {{medline-title
|title=Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation.
|title=[Role and alterations of DNA methylation during the aging and cancer].
|date=15.09.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32010971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496346
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
}}
}}
==CDH2==
* {{medline-title
* {{medline-title
|title=CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type.
|title=Thyroid hormone activates Wnt/β-catenin signaling involved in adult epithelial development during intestinal remodeling in Xenopus laevis.
|date=30.11.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27068920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265269
|full-text-url=https://sci-hub.do/10.1007/s00441-016-2396-8
}}
}}
==CDKN1B==
==SHANK3==


* {{medline-title
* {{medline-title
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|title=Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background.
|date=2018
|date=10.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30305163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180595
}}
}}
==CDKN1C==
* {{medline-title
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|title=Adult restoration of Shank3 expression rescues selective autistic-like phenotypes.
|date=18.03.2019
|date=25.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26886798
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898763
}}
}}
==CDO1==
==SHB==


* {{medline-title
* {{medline-title
|title=The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway.
|title=Longitudinal Relationships between Reproductive Hormones and Cognitive Decline in Older Men: The Concord Health and Ageing in Men Project.
|date=19.09.2018
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25867811
|full-text-url=https://sci-hub.do/10.1039/c8fo00740c
|full-text-url=https://sci-hub.do/10.1210/jc.2015-1016
}}
}}
==CDR1==
* {{medline-title
* {{medline-title
|title=Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires.
|title='Carriers of variant luteinizing hormone (V-LH) among 1593 Baltic men have significantly higher serum LH'.
|date=2018
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403498
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25820123
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832392
}}
}}
==CDX2==
==SIX3==


* {{medline-title
* {{medline-title
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|title=CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type.
|date=08.07.2019
|date=30.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102368
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265269
}}
}}
==CEBPB==
* {{medline-title
* {{medline-title
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|title=Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.
|date=2018
|date=10.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27133132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864151
}}
}}
==CEBPD==
==SLC13A5==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=INDY-A New Link to Metabolic Regulation in Animals and Humans.
|date=10.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28596784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442177
}}
}}
==CEL==
* {{medline-title
* {{medline-title
|title=Nanocarrier-Mediated Chemo-Immunotherapy Arrested Cancer Progression and Induced Tumor Dormancy in Desmoplastic Melanoma.
|title=The role of INDY in metabolism, health and longevity.
|date=28.08.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30016071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26106407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115293
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460575
}}
}}
==CES1==
==SLC19A1==


* {{medline-title
* {{medline-title
|title=[Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog].
|title=Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer.
|date=2019
|date=30.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31061351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29682186
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00228
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908287
}}
}}
==CETP==
* {{medline-title
* {{medline-title
|title=Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study.
|title=Association of [[MTHFR]], [[SLC19A1]] Genetic Polymorphism, Serum Folate, Vitamin B  and Hcy Status with Cognitive Functions in Chinese Adults.
|date=2018
|date=24.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30159092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27783031
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084051
}}
}}
==CFB==
==SLC24A4==


* {{medline-title
* {{medline-title
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye.
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=13.06.2018
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
}}
==CFH==
* {{medline-title
* {{medline-title
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye.
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=13.06.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
}}
==CHAT==
==SLC25A24==


* {{medline-title
* {{medline-title
|title=Satisfaction and Technology Evaluation of a Telehealth Robotic Program to Optimize Healthy Independent Living for Older Adults.
|title=De Novo Mutations in [[SLC25A24]] Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.
|date=11.2018
|date=02.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29100094
|full-text-url=https://sci-hub.do/10.1111/jnu.12436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673633
}}
* {{medline-title
|title=De Novo Mutations in [[SLC25A24]] Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction.
|date=02.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29100093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673623
}}
}}
==CHEK2==
==SLC6A3==


* {{medline-title
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|title=A variable number of tandem repeats in the 3'-untranslated region of the dopamine transporter modulates striatal function during working memory updating across the adult age span.
|date=20.06.2019
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25997640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
|full-text-url=https://sci-hub.do/10.1111/ejn.12956
}}
}}
==CHIA==
* {{medline-title
* {{medline-title
|title=Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets.
|title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus.
|date=26.11.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30486328
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316572
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460
}}
}}
==CHL1==
==SLC7A11==


* {{medline-title
* {{medline-title
|title=Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B.
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|date=07.08.2019
|date=28.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182634
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687901
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
}}
}}
==CHRM4==
* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Comprehensive Analysis of Interaction Networks of Telomerase Reverse Transcriptase with Multiple Bioinformatic Approaches: Deep Mining the Potential Functions of Telomere and Telomerase.
|date=15.11.2018
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28281877
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1089/rej.2016.1909
}}
}}
==CHRNA7==
==SLN==


* {{medline-title
* {{medline-title
|title=Associations between genetic variations and global motion perception.
|title=Completion Lymph Node Dissection or Observation for Melanoma Sentinel Lymph Node Metastases: A Decision Analysis.
|date=10.2019
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31432227
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27194553
|full-text-url=https://sci-hub.do/10.1007/s00221-019-05627-7
|full-text-url=https://sci-hub.do/10.1245/s10434-016-5273-5
}}
}}
==CHRNE==
* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Age differences in brain activity related to unsuccessful declarative memory retrieval.
|date=15.11.2018
|date=01.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25541365
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898958
}}
}}
==CHSY1==
==SMAD1==


* {{medline-title
* {{medline-title
|title=Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in [i]skt[/i] Mice.
|title=TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands.
|date=01.2020
|date=26.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944401
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928867
}}
}}
==CINP==
* {{medline-title
* {{medline-title
|title=Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging.
|title=BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence.
|date=01-03.2019
|date=15.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30681437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27794120
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000294
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135304
}}
}}
==CIP2A==
==SMAD7==


* {{medline-title
* {{medline-title
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|title=Forkhead Box Protein 1 (FoxO1) Inhibits Accelerated β Cell Aging in Pancreas-specific [[SMAD7]] Mutant Mice.
|date=08.01.2018
|date=24.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28057752
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336177
}}
* {{medline-title
|title=Granulosa cell function and oocyte competence: Super-follicles, super-moms and super-stimulation in cattle.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25107564
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2014.07.016
}}
}}
==CIZ1==
==SMO==


* {{medline-title
* {{medline-title
|title=DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice.
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|date=02.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154038
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
}}
}}
==CLEC3B==
* {{medline-title
* {{medline-title
|title=[[CLEC3B]] p.S106G Mutant in a Caucasian Population of Successful Neurological Aging.
|title=Silybum marianum oil attenuates oxidative stress and ameliorates mitochondrial dysfunction in mice treated with D-galactose.
|date=16.09.2020
|date=01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570938
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24914315
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047594
}}
}}
==CLEC4E==
==SMOX==


* {{medline-title
* {{medline-title
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|title=Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine.
|date=03.2018
|date=14.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29443878
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872171
}}
}}
==CLN3==
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Haemocytes control stem cell activity in the Drosophila intestine.
|date=09.2017
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005834
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449816
}}
}}
==CNP==
==SNCB==


* {{medline-title
* {{medline-title
|title=Environmental Enrichment Elicits a Transient Rise of Bioactive C-Type Natriuretic Peptide in Young but Not Aged Rats.
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|date=2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30072880
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060231
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
}}
}}
==CNTF==
* {{medline-title
* {{medline-title
|title=Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha.
|title=Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro.
|date=01.10.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30861131
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656591
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047277
}}
}}
==CNTNAP2==
==SOCS2==


* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=Suppressor of Cytokine Signalling 2 ([[SOCS2]]) Regulates Numbers of Mature Newborn Adult Hippocampal Neurons and Their Dendritic Spine Maturation.
|date=05.2017
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27655030
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://sci-hub.do/10.1007/s10571-016-0427-3
}}
}}
==COL12A1==
* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Age-independent effects of hyaluronan amide derivative and growth hormone on human osteoarthritic chondrocytes.
|date=10.2019
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26075645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://sci-hub.do/10.3109/03008207.2015.1047928
}}
}}
==COL13A1==
==SPARCL1==


* {{medline-title
* {{medline-title
|title=[Alu insertion-deletion polymorphism of [[COL13A1]] and [[LAMA2]] genes: The analysis of association with longevity].
|title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment.
|date=10.2016
|date=18.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369589
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664
}}
* {{medline-title
|title=[[SPARCL1]] Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934753
}}
}}
==COL1A1==
==SPON1==


* {{medline-title
* {{medline-title
|title=Remodeling process in bone of aged rats in response to resistance training.
|title=[[APOE]] influences working memory in non-demented elderly through an interaction with [[SPON1]] rs2618516.
|date=01.09.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593709
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573041
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866309
}}
}}
==COL2A1==
* {{medline-title
* {{medline-title
|title=Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis.
|title=HYDRA: Revealing heterogeneity of imaging and genetic patterns through a multiple max-margin discriminative analysis framework.
|date=08.02.2018
|date=15.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415892
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26923371
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821202
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408358
}}
}}
==COL6A1==
==SRR==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Mediterranean diet and its components in relation to all-cause mortality: meta-analysis.
|date=10.2019
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30401007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.1017/S0007114518002593
}}
}}
==COQ5==
* {{medline-title
* {{medline-title
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=18.09.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
}}
==COQ6==
==SRY==


* {{medline-title
* {{medline-title
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|title=Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics.
|date=18.09.2018
|date=26.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29371932
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768349
}}
}}
==COQ7==
* {{medline-title
* {{medline-title
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|title=Regulation of senescence associated signaling mechanisms in chondrocytes for cartilage tissue regeneration.
|date=18.09.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26190795
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
|full-text-url=https://sci-hub.do/10.1016/j.joca.2015.07.008
}}
}}
==COQ9==
==SSTR1==


* {{medline-title
* {{medline-title
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|title=Expression and localization of somatostatin receptor types 3, 4 and 5 in the wild-type, [[SSTR1]] and [[SSTR1]]/SSTR2 knockout mouse cochlea.
|date=18.09.2018
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25149275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
|full-text-url=https://sci-hub.do/10.1007/s00441-014-1977-7
}}
}}
==CPNE1==
* {{medline-title
* {{medline-title
|title=Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence.
|title=Upregulated expression of [[SSTR1]] is involved in neuronal apoptosis and is coupled to the reduction of bcl-2 following intracerebral hemorrhage in adult rats.
|date=04.12.2020
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274830
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25035058
|full-text-url=https://sci-hub.do/10.1111/acel.13276
|full-text-url=https://sci-hub.do/10.1007/s10571-014-0081-6
}}
}}
==CPT1A==
==ST6GAL1==


* {{medline-title
* {{medline-title
|title=Alteration of fatty acid oxidation by increased [[CPT1A]] on replicative senescence of placenta-derived mesenchymal stem cells.
|title=Glycobiology of Aging.
|date=03.01.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31900237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30779020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941254
|full-text-url=https://sci-hub.do/10.1007/978-981-13-2835-0_17
}}
}}
==CPT1B==
* {{medline-title
* {{medline-title
|title=Effects of carnitine palmitoyltransferases on cancer cellular senescence.
|title=Identification of novel plasma glycosylation-associated markers of aging.
|date=02.2019
|date=16.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30070697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26840264
|full-text-url=https://sci-hub.do/10.1002/jcp.27042
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884931
}}
}}
==CPT2==
==STAT5A==


* {{medline-title
* {{medline-title
|title=The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=09.2020
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32729662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511879
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==CR2==
* {{medline-title
* {{medline-title
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|date=19.01.2019
|date=28.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
}}
}}
==CRBN==
==STK3==


* {{medline-title
* {{medline-title
|title=Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity.
|title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence.
|date=24.04.2020
|date=11.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32332723
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181703
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934
}}
}}
==CREB1==
* {{medline-title
* {{medline-title
|title=Arginine Methyltransferase [[PRMT8]] Provides Cellular Stress Tolerance in Aging Motoneurons.
|title=Organ-specific alteration in caspase expression and [[STK3]] proteolysis during the aging process.
|date=29.08.2018
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552481
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113905
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.07.003
}}
}}
==CREB5==
==STN1==


* {{medline-title
* {{medline-title
|title=Cellular senescence induces replication stress with almost no affect on DNA replication timing.
|title=[[CTC1]]-[[STN1]] coordinates G- and C-strand synthesis to regulate telomere length.
|date=2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963964
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479
}}
}}
==CREBBP==
* {{medline-title
* {{medline-title
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms.
|title=A gain-of-function senescence bypass screen identifies the homeobox transcription factor [[DLX2]] as a regulator of [[ATM]]-p53 signaling.
|date=22.07.2019
|date=01.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26833729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743059
}}
}}
==CREM==
==SURF1==


* {{medline-title
* {{medline-title
|title=Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells.
|title=Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.
|date=11.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250567
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696791
|full-text-url=https://sci-hub.do/10.1111/andr.12665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052393
}}
* {{medline-title
|title=Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses.
|date=01.09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24911525
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145821
}}
}}
==CRISPLD2==
==SUZ12==


* {{medline-title
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
|date=20.06.2019
|date=05.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005
}}
}}
==CRY2==
* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes.
|date=21.11.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25880792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623031
}}
}}
==CRYAB==
==SV2A==


* {{medline-title
* {{medline-title
|title=Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
|title=Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging.
|date=28.12.2018
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389787
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30014145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233853
}}
}}
==CSAD==
* {{medline-title
* {{medline-title
|title=The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway.
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|date=19.09.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|full-text-url=https://sci-hub.do/10.1039/c8fo00740c
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
}}
}}
==CSF3R==
==SYNJ1==


* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer's Disease.
|date=13.11.2018
|date=05.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29874583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040810
}}
}}
==CTC1==
* {{medline-title
* {{medline-title
|title=[[CTC1]]-[[STN1]] coordinates G- and C-strand synthesis to regulate telomere length.
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=08.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
}}
==CTNS==
==TAL1==


* {{medline-title
* {{medline-title
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading.
|title=Transcriptomic analysis of purified human cortical microglia reveals age-associated changes.
|date=05.2020
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869
|full-text-url=https://sci-hub.do/10.1038/nn.4597
}}
}}
==CTSA==
* {{medline-title
* {{medline-title
|title=A [[CTSA]]-based consultation service to advance research on special and underserved populations.
|title=Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex.
|date=16.01.2020
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33244406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26002684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503803
}}
}}
==CTSL==
==TAP1==


* {{medline-title
* {{medline-title
|title=Cathepsin L deficiency results in reactive oxygen species (ROS) accumulation and vascular cells activation.
|title=Age-associated methylation change of [[TAP1]] promoter in piglet.
|date=12.2017
|date=15.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29041825
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26169022
|full-text-url=https://sci-hub.do/10.1080/10715762.2017.1393665
|full-text-url=https://sci-hub.do/10.1016/j.gene.2015.07.026
}}
}}
==CTSS==
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Lifespan of mice and primates correlates with immunoproteasome expression.
|date=09.2017
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25866968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463211
}}
}}
==CUL3==
==TARDBP==


* {{medline-title
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|title=Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.
|date=05.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577934
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
|full-text-url=https://sci-hub.do/10.1016/j.ajpath.2018.03.002
}}
}}
==CUX1==
* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.
|date=15.04.2019
|date=24.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225
}}
}}
==CXCL13==
==TAS2R16==


* {{medline-title
* {{medline-title
|title=RNA-seq data from C-X-C chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype.
|title=Taste receptor polymorphisms and longevity: a systematic review and meta-analysis.
|date=08.2020
|date=10.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32642521
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33170488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334305
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01745-3
}}
}}
==CXCL14==
* {{medline-title
* {{medline-title
|title=Identification of genes associated with endometrial cell aging.
|title=Taste receptors, innate immunity and longevity: the case of [[TAS2R16]] gene.
|date=01.12.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33258951
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30833980
|full-text-url=https://sci-hub.do/10.1093/molehr/gaaa078
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387736
}}
}}
==CXCL16==
==TBC1D5==


* {{medline-title
* {{medline-title
|title=[[CXCR6]] Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and [[CD4]]  T-Cell-Dependent Control of Senescence.
|title=[[TBC1D5]]-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry.
|date=05.2019
|date=09.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710528
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32521275
|full-text-url=https://sci-hub.do/10.1053/j.gastro.2019.01.247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339955
}}
}}
==CXCL17==
* {{medline-title
* {{medline-title
|title=[Age-related aspects of the involvement of heat shock proteins in the pathogenesis of osteoarthritis].
|title=Retromer and [[TBC1D5]] maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling.
|date=2017
|date=02.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849876
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31431476
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719456
}}
}}
==CXCR1==
==TBK1==


* {{medline-title
* {{medline-title
|title=Harmful neutrophil subsets in patients with ischemic stroke: Association with disease severity.
|title=Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of [[TBK1]] to facilitate mitophagy.
|date=07.2019
|date=01.01.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31355307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33164878
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624098
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165997
}}
}}
==CXCR5==
* {{medline-title
* {{medline-title
|title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses.
|title=[[TBK1]] Suppresses [[RIPK1]]-Driven Apoptosis and Inflammation during Development and in Aging.
|date=17.08.2017
|date=06.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30146158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128749
}}
}}
==CXCR6==
==TCF7==


* {{medline-title
* {{medline-title
|title=[[CXCR6]] Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and [[CD4]]  T-Cell-Dependent Control of Senescence.
|title=Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice.
|date=05.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710528
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29206307
|full-text-url=https://sci-hub.do/10.1053/j.gastro.2019.01.247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925424
}}
}}
==CYB5A==
* {{medline-title
* {{medline-title
|title=11-Oxygenated C19 Steroids Do Not Decline With Age in Women.
|title=Age-related profiling of DNA methylation in CD8  T cells reveals changes in immune response and transcriptional regulator genes.
|date=01.07.2019
|date=19.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26286994
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525564
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541364
}}
}}
==CYB5R3==
==TDG==


* {{medline-title
* {{medline-title
|title=Overexpression of [[CYB5R3]] and [[NQO1]], two NAD  -producing enzymes, mimics aspects of caloric restriction.
|title=lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/[[TDG]] axis.
|date=08.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714223
}}
}}
==CYP11B1==
* {{medline-title
* {{medline-title
|title=Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼.
|title=Survival Rates of Out-Migrating Yearling Chinook Salmon in the Lower Columbia River and Plume after Exposure to Gas-Supersaturated Water.
|date=11.2020
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002589
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28005490
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105764
|full-text-url=https://sci-hub.do/10.1080/08997659.2016.1227398
}}
}}
==CYP11B2==
==TDP1==


* {{medline-title
* {{medline-title
|title=Expression of aldosterone synthase [[CYP11B2]] was inversely correlated with longevity.
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|date=07.2019
|date=12.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30974191
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
}}
}}
==CYP17A1==
* {{medline-title
* {{medline-title
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio).
|title=Neuroprotection and repair of 3'-blocking DNA ends by glaikit (gkt) encoding Drosophila tyrosyl-DNA phosphodiesterase 1 ([[TDP1]]).
|date=03.2018
|date=04.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25331878
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226126
}}
}}
==CYP19A1==
==TEAD1==


* {{medline-title
* {{medline-title
|title=Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model.
|title=[Role of [[PLAT]], [[PKHD1L1]], [[STK38L]] and [[TEAD1]] genes Alu-polymorphism for longevity].
|date=06.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28556638
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.016
 
}}
}}
==CYP1B1==
* {{medline-title
* {{medline-title
|title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts.
|title=Acetylation of [[VGLL4]] Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth.
|date=04.2018
|date=21.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27720608
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121000
}}
}}
==CYP24A1==
==TERF1==


* {{medline-title
* {{medline-title
|title=Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism.
|title=Telomere protein RAP1 levels are affected by cellular aging and oxidative stress.
|date=22.02.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27446538
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950791
}}
}}
==CYP26A1==
* {{medline-title
* {{medline-title
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|title=Population-specific association of genes for telomere-associated proteins with longevity in an Italian population.
|date=08.10.2018
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25631672
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
|full-text-url=https://sci-hub.do/10.1007/s10522-015-9551-6
}}
}}
==CYP26B1==
==TIMELESS==


* {{medline-title
* {{medline-title
|title=Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia.
|title=Loss of circadian protein [[TIMELESS]] accelerates the progression of cellular senescence.
|date=20.05.2020
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32385093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30100061
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244205
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.040
}}
}}
==CYP2C9==
* {{medline-title
* {{medline-title
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
|title=Clock gene expression and locomotor activity predict death in the last days of life in Drosophila melanogaster.
|date=12.2017
|date=09.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30093652
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085321
}}
}}
==CYP2R1==
==TIMP2==


* {{medline-title
* {{medline-title
|title=Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance.
|title=The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma.
|date=01.08.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955863
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30252623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693043
|full-text-url=https://sci-hub.do/10.1080/09537104.2018.1514110
}}
}}
==CYP3A5==
* {{medline-title
* {{medline-title
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia.
|title=Human umbilical cord plasma proteins revitalize hippocampal function in aged mice.
|date=12.2017
|date=27.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28424512
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586222
}}
}}
==DAP==
==TLR3==


* {{medline-title
* {{medline-title
|title=Examining changes in the equity of physician distribution in Japan: a specialty-specific longitudinal study.
|title=Repetitive [[TLR3]] activation in the lung induces skeletal muscle adaptations and cachexia.
|date=08.01.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29317415
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452288
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911410
}}
}}
==DAPK2==
* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Age-related changes and distribution of T cell markers (CD3 and [[CD4]]) and toll-like receptors(TLR2, [[TLR3]],[[TLR4]] and [[TLR7]]) in the duck lymphoid organs.
|date=04.07.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356195
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1016/j.imbio.2017.01.004
}}
}}
==DAXX==
==TMEM119==


* {{medline-title
* {{medline-title
|title=[[ATRX]]-[[DAXX]] Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains.
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|date=09.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31361513
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|full-text-url=https://sci-hub.do/10.1089/dna.2019.4752
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
}}
}}
==DAZL==
* {{medline-title
* {{medline-title
|title=[[DAZL]] Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.
|title=Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis.
|date=30.10.2018
|date=01.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28541408
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878787
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057548
}}
}}
==DBH==
==TMPRSS2==


* {{medline-title
* {{medline-title
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children.
|title=Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants.
|date=04.2019
|date=09.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32905655
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711
|full-text-url=https://sci-hub.do/10.1002/jbt.22626
}}
}}
==DBT==
* {{medline-title
* {{medline-title
|title=Diurnal rhythms of heart and respiratory rates in donkeys of different age groups during the cold-dry and hot-dry seasons in a tropical savannah.
|title=Expression of the SARS-CoV-2 Entry Proteins, ACE2 and [[TMPRSS2]], in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age.
|date=09.2018
|date=03.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32379417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241737
}}
}}
==DCAF17==
==TOMM20==


* {{medline-title
* {{medline-title
|title=Deletion of [[DDB1]]- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice.
|title=Effect of aging on mitochondria and metabolism of bovine granulosa cells.
|date=15.06.2018
|date=13.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907856
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32921645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003934
|full-text-url=https://sci-hub.do/10.1262/jrd.2020-071
}}
}}
==DCLRE1C==
* {{medline-title
* {{medline-title
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|title=PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis.
|date=06.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25714760
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502689
}}
}}
==DCTN2==
==TOP1==


* {{medline-title
* {{medline-title
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|date=09.2019
|date=12.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
}}
}}
==DCTN3==
* {{medline-title
* {{medline-title
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|title=mir-24 activity propagates stress-induced senescence by down regulating DNA topoisomerase 1.
|date=09.2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26748253
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.12.012
}}
}}
==DCTN6==
==TOX==


* {{medline-title
* {{medline-title
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|title=Temporal Cognitive Decline Associated With Exposure to Infectious Agents in a Population-based, Aging Cohort.
|date=09.2019
|date=07-09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26710257
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919236
}}
}}
==DDI2==
* {{medline-title
* {{medline-title
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
|title=[[TH]]E EFFECTS OF XAN[[TH]]O[[TOX]]IN ON [[TH]]E BIOLOGY AND BIOCHEMISTRY OF Galleria mellonella L. ([[LEP]]IDO[[PTER]]A: PYRALIDAE).
|date=01.08.2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25821173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498
|full-text-url=https://sci-hub.do/10.1002/arch.21236
}}
}}
==DDIT3==
==TPH2==


* {{medline-title
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|title=Ageing and gastrointestinal sensory function: altered colonic mechanosensory and chemosensory function in the aged mouse.
|date=2018
|date=15.08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26592729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983623
}}
}}
==DDR1==
* {{medline-title
* {{medline-title
|title=Age-related modifications of type I collagen impair [[DDR1]]-induced apoptosis in non-invasive breast carcinoma cells.
|title=Effect of tryptophan hydroxylase-2 gene polymorphism G-703 T on personality in a population representative sample.
|date=2018
|date=03.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733741
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25455586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363044
|full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2014.10.005
}}
}}
==DDR2==
==TRAF2==


* {{medline-title
* {{medline-title
|title=Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging.
|title=The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium.
|date=03.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31042012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711781
}}
}}
==DEPDC5==
* {{medline-title
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|title=Ubiquitination of inositol-requiring enzyme 1 (IRE1) by the E3 ligase CHIP mediates the IRE1/[[TRAF2]]/JNK pathway.
|date=05.2018
|date=31.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25225294
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215236
}}
}}
==DEPTOR==
==TREX1==


* {{medline-title
* {{medline-title
|title=[[DEPTOR]] at the Nexus of Cancer, Metabolism, and Immunity.
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|date=01.07.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
}}
}}
==DES==
* {{medline-title
* {{medline-title
|title=Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=20.03.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29558926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859529
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==DGAT1==
==TRH==


* {{medline-title
* {{medline-title
|title=Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPα-p300/[[DGAT1]] pathway.
|title=Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats.
|date=02.2018
|date=15.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29305326
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771394
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2017.12.029
}}
}}
==DGAT2==
* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=Effect of dietary carbohydrates and time of year on ACTH and cortisol concentrations in adult and aged horses.
|date=08.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195115
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2017.10.005
}}
}}
==DGCR8==
==TRIM28==


* {{medline-title
* {{medline-title
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif.
|title=Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau.
|date=29.04.2019
|date=04.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29863470
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993537
}}
}}
==DHRS2==
* {{medline-title
* {{medline-title
|title=Acute [[HSF1]] depletion induces cellular senescence through the [[MDM2]]-p53-p21 pathway in human diploid fibroblasts.
|title=Polyphenic trait promotes liver cancer in a model of epigenetic instability in mice.
|date=08.05.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632240
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28370258
|full-text-url=https://sci-hub.do/10.1242/jcs.210724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518198
}}
}}
==DIAPH1==
==TRIP13==


* {{medline-title
* {{medline-title
|title=Diaphanous 1 ([[DIAPH1]]) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease.
|title=BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.
|date=2018
|date=02.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966194
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31738183
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934189
}}
}}
==DIP2A==
* {{medline-title
* {{medline-title
|title=Blocking the [[FSTL1]]-[[DIP2A]] Axis Improves Anti-tumor Immunity.
|title=PCH-2 regulates Caenorhabditis elegans lifespan.
|date=14.08.2018
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30110636
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25635513
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.07.043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350321
}}
}}
==DKK2==
==TRPC3==


* {{medline-title
* {{medline-title
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women.
|title=Age-dependent alpha-synuclein accumulation is correlated with elevation of mitochondrial [[TRPC3]] in the brains of monkeys and mice.
|date=07.2019
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27904950
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448
|full-text-url=https://sci-hub.do/10.1007/s00702-016-1654-y
}}
}}
==DLAT==
* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=[[TRPC3]] channels critically regulate hippocampal excitability and contextual fear memory.
|date=02.2018
|date=15.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25513972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677051
}}
}}
==DLC1==
==TRPC5==


* {{medline-title
* {{medline-title
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells.
|title=[[TRPC5]] channel modulates endothelial cells senescence.
|date=15.09.2018
|date=05.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28237267
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2017.02.037
}}
* {{medline-title
|title=Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27854075
|full-text-url=https://sci-hub.do/10.1007/s11010-016-2884-x
}}
}}
==DLGAP2==
==TRPC6==


* {{medline-title
* {{medline-title
|title=Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
|title=Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype.
|date=01.09.2020
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32877673
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32686475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502175
|full-text-url=https://sci-hub.do/10.1177/1535370220943122
}}
* {{medline-title
|title=[[TRPC6]] in simulated microgravity of intervertebral disc cells.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29968164
|full-text-url=https://sci-hub.do/10.1007/s00586-018-5688-8
}}
}}
==DLL1==
==TRPM6==


* {{medline-title
* {{medline-title
|title=MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting [[DLL1]] and Regulating PI3K/AKT Pathway.
|title=Role of kinase-coupled TRP channels in mineral homeostasis.
|date=2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129644
|full-text-url=https://sci-hub.do/10.1159/000492090
|full-text-url=https://sci-hub.do/10.1016/j.pharmthera.2017.11.003
}}
}}
==DLL4==
* {{medline-title
* {{medline-title
|title=Dynamic regulation of [[NOTCH1]] activation and Notch ligand expression in human thymus development.
|title=Epithelial magnesium transport by [[TRPM6]] is essential for prenatal development and adult survival.
|date=13.08.2018
|date=19.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30042180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27991852
|full-text-url=https://sci-hub.do/10.1242/dev.165597
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218537
}}
}}
==DMP1==
==TRPM7==


* {{medline-title
* {{medline-title
|title=Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice.
|title=mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development.
|date=07.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29842890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029870
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.05.008
}}
}}
==DMPK==
* {{medline-title
* {{medline-title
|title=Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans.
|title=Role of kinase-coupled TRP channels in mineral homeostasis.
|date=19.04.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30878478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129644
|full-text-url=https://sci-hub.do/10.1016/j.jmb.2019.03.003
|full-text-url=https://sci-hub.do/10.1016/j.pharmthera.2017.11.003
}}
}}
==DNAJB9==
==TRPV6==


* {{medline-title
* {{medline-title
|title=[[DNAJB9]] Inhibits p53-Dependent Oncogene-Induced Senescence and Induces Cell Transformation.
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|date=30.04.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32264658
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191047
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
}}
}}
==DNM1==
* {{medline-title
* {{medline-title
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.
|title=Molecular aspects of intestinal calcium absorption.
|date=2018
|date=21.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26109800
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476875
}}
}}
==DNM2==
==TSHB==


* {{medline-title
* {{medline-title
|title=Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy.
|title=Adipose [[TSHB]] in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence.
|date=19.11.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451843
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448824
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243013
|full-text-url=https://sci-hub.do/10.1159/000495170
}}
* {{medline-title
|title=Loss of basal and TRH-stimulated Tshb expression in dispersed pituitary cells.
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25356823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272397
}}
}}
==DNMT3L==
==TSLP==


* {{medline-title
* {{medline-title
|title=Transient [[DNMT3L]] Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast.
|title=Cloning and expression of recombinant equine interleukin-3 and its effect on sulfidoleukotriene and cytokine production by equine peripheral blood leukocytes.
|date=2020
|date=15.02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32195249
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25530476
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064442
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2014.11.012
}}
}}
==DOCK11==
* {{medline-title
* {{medline-title
|title=[Immunosenescence: The Forefront of Infection and Trophic Control].
|title=Accumulation of prelamin A compromises NF-κB-regulated B-lymphopoiesis in a progeria mouse model.
|date=2020
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115558
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24764515
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00193-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922919
}}
}}
==DOT1L==
==TTN==


* {{medline-title
* {{medline-title
|title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction.
|title=LncRNA [[TTN]]-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis.
|date=04.2018
|date=10.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31600142
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814585
}}
}}
==DPP6==
* {{medline-title
* {{medline-title
|title=A novel structure associated with aging is augmented in the [[DPP6]]-KO mouse brain.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=23.11.2020
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33225987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682109
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==DPT==
==TYR==


* {{medline-title
* {{medline-title
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography.
|title=Phosphorylation of [[MITF]] by AKT affects its downstream targets and causes [[TP53]]-dependent cell senescence.
|date=12.2017
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27702651
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2016.09.029
}}
}}
==DPYSL2==
* {{medline-title
* {{medline-title
|title=Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease.
|title=Gene expression profiling to investigate tyrosol-induced lifespan extension in Caenorhabditis elegans.
|date=2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31733664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25804201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939615
|full-text-url=https://sci-hub.do/10.1007/s00394-015-0884-3
}}
}}
==DRAM1==
==U2AF1==


* {{medline-title
* {{medline-title
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
|title=Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs.
|date=12.2019
|date=05.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32141009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01509-z
}}
}}
==DRAM2==
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy.
|date=09.2017
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27147278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://sci-hub.do/10.1111/ejh.12771
}}
}}
==DRD1==
==UBB==


* {{medline-title
* {{medline-title
|title=Impact of dopamine-related genetic variants on physical activity in old age - a cohort study.
|title=Different Expression Levels of Human Mutant Ubiquitin B  ([[UBB]] ) Can Modify Chronological Lifespan or Stress Resistance of [i]Saccharomyces cerevisiae[/i].
|date=24.05.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32448293
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29950972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245799
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008557
}}
}}
==DRD4==
* {{medline-title
* {{medline-title
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children.
|title=Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast.
|date=04.2019
|date=20.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28357285
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348975
}}
}}
==DROSHA==
==UGT1A1==


* {{medline-title
* {{medline-title
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability.
|title=Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain.
|date=06.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25953521
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468441
}}
}}
==DSC1==
* {{medline-title
* {{medline-title
|title=HDLs and the pathogenesis of atherosclerosis.
|title=Age-related changes in mRNA levels of hepatic transporters, cytochrome P450 and UDP-glucuronosyltransferase in female rats.
|date=05.2018
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29561322
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24899460
|full-text-url=https://sci-hub.do/10.1097/HCO.0000000000000508
|full-text-url=https://sci-hub.do/10.1007/s13318-014-0208-7
}}
}}
==DSCAM==
==ULBP2==


* {{medline-title
* {{medline-title
|title=Age- and speed-dependent modulation of gaits in [[DSCAM]]  mutant mice.
|title=NKG2D ligands mediate immunosurveillance of senescent cells.
|date=01.02.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29093169
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26878797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867377
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789586
}}
}}
==DSE==
* {{medline-title
* {{medline-title
|title=Impact of Intensive Lifestyle Intervention on Disability-Free Life Expectancy: The Look AHEAD Study.
|title=Type 1 interferons contribute to the clearance of senescent cell.
|date=05.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545462
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26046815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622626
}}
}}
==DSPP==
==UMOD==


* {{medline-title
* {{medline-title
|title=Effects of [i]p[/i]-Cresol on Senescence, Survival, Inflammation, and Odontoblast Differentiation in Canine Dental Pulp Stem Cells.
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes.
|date=21.09.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32967298
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468
}}
}}
==DTL==
* {{medline-title
* {{medline-title
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|title=A roadmap for the genetic analysis of renal aging.
|date=2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26219736
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568960
}}
}}
==DTNBP1==
==UNG==


* {{medline-title
* {{medline-title
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|title=[[UNG]]-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.
|date=2017
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717169
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931555
}}
}}
==DUSP1==
* {{medline-title
* {{medline-title
|title=miR-1468-3p Promotes Aging-Related Cardiac Fibrosis.
|title=Caenorhabditis elegans EXO-3 contributes to longevity and reproduction: differential roles in somatic cells and germ cells.
|date=05.06.2020
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32348937
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25772110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191129
|full-text-url=https://sci-hub.do/10.1016/j.mrfmmm.2015.01.001
}}
}}
==DUSP2==
==UQCRC2==


* {{medline-title
* {{medline-title
|title=Aging Increases Hippocampal [[DUSP2]] by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism.
|title=Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10).
|date=2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31293510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603139
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.025
}}
* {{medline-title
|title=Resveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26873850
|full-text-url=https://sci-hub.do/10.1007/s12035-016-9770-0
}}
}}
==DUSP8==
==VASH1==


* {{medline-title
* {{medline-title
|title=MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats.
|title=Double-Face of Vasohibin-1 for the Maintenance of Vascular Homeostasis and Healthy Longevity.
|date=12.2019
|date=01.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31400088
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29398681
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005230
}}
}}
==DUT==
* {{medline-title
* {{medline-title
|title=Simultaneous liquefaction, saccharification, and fermentation of L-lactic acid using aging paddy rice with hull by an isolated thermotolerant Enterococcus faecalis [[DUT]]1805.
|title=Age-associated downregulation of vasohibin-1 in vascular endothelial cells.
|date=09.2020
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32388689
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27325558
|full-text-url=https://sci-hub.do/10.1007/s00449-020-02364-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013028
}}
}}
==DYNC2H1==
==VASP==


* {{medline-title
* {{medline-title
|title=Role for intraflagellar transport in building a functional transition zone.
|title=Reversal of Aging-Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein-Protein Interfaces.
|date=12.2018
|date=18.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021807
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280794
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201469
}}
}}
==DYRK1A==
* {{medline-title
* {{medline-title
|title=Altered age-linked regulation of plasma [[DYRK1A]] in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load.
|title=In vitro anti-platelet potency of ticagrelor in blood samples from infants and children.
|date=2020
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32642550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26210892
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331462
|full-text-url=https://sci-hub.do/10.1016/j.thromres.2015.07.013
}}
}}
==E2F3==
==VCAN==


* {{medline-title
* {{medline-title
|title=Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution.
|title=Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis.
|date=07.2018
|date=07.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730547
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31051334
|full-text-url=https://sci-hub.do/10.1016/j.molimm.2018.04.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495079
}}
}}
==ECM1==
* {{medline-title
* {{medline-title
|title=Novel role of extracellular matrix protein 1 ([[ECM1]]) in cardiac aging and myocardial infarction.
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223
}}
}}
==ECRG4==
==VEGFA==


* {{medline-title
* {{medline-title
|title=[[ECRG4]]: a new potential target in precision medicine.
|title=APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease.
|date=10.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31791659
|full-text-url=https://sci-hub.do/10.1007/s11684-018-0637-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064375
}}
* {{medline-title
|title=Regulation of Vegf signaling by natural and synthetic ligands.
|date=10.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27557946
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766839
}}
}}
==ECSIT==
==VGF==


* {{medline-title
* {{medline-title
|title=Longevity-related molecular pathways are subject to midlife "switch" in humans.
|title=Voluntary Running Triggers [[VGF]]-Mediated Oligodendrogenesis to Prolong the Lifespan of Snf2h-Null Ataxic Mice.
|date=08.2019
|date=11.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168962
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27732860
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612641
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2016.09.030
}}
* {{medline-title
|title=Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans.
|date=06.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26337083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745765
}}
}}
==EDEM1==
==VGLL3==


* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon (Salmo salar L.) Males.
|date=08.2019
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26551894
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4638356
}}
}}
==EDF1==
* {{medline-title
* {{medline-title
|title=Silencing of FOREVER YOUNG FLOWER Like Genes from Phalaenopsis Orchids Promotes Flower Senescence and Abscission.
|title=Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon.
|date=25.11.2020
|date=17.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33237274
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26536110
|full-text-url=https://sci-hub.do/10.1093/pcp/pcaa145
|full-text-url=https://sci-hub.do/10.1038/nature16062
}}
}}
==EDN1==
==VGLL4==


* {{medline-title
* {{medline-title
|title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway.
|title=The lncRNA MEG3/miR-16-5p/[[VGLL4]] regulatory axis is involved in etoposide-induced senescence of tumor cells.
|date=03.2018
|date=03.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33141998
|full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0
|full-text-url=https://sci-hub.do/10.1002/jgm.3291
}}
}}
==EED==
* {{medline-title
* {{medline-title
|title=Economic evaluations of eHealth technologies: A systematic review.
|title=Acetylation of [[VGLL4]] Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth.
|date=2018
|date=21.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897921
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27720608
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121000
}}
}}
==EFEMP1==
==VIT==


* {{medline-title
* {{medline-title
|title=A novel age-related venous amyloidosis derived from [[EGF]]-containing fibulin-like extracellular matrix protein 1.
|title=Autophagy-mediated longevity is modulated by lipoprotein biogenesis.
|date=04.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30565683
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26671266
|full-text-url=https://sci-hub.do/10.1002/path.5203
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836030
}}
}}
==EHF==
* {{medline-title
* {{medline-title
|title=Extended high frequency hearing and speech perception implications in adults and children.
|title=ASSOCIATION OF PREVASCUL[[AR]] [[VIT]]REOUS FISSURES AND CISTERNS WI[[TH]] [[VIT]]REOUS DEGENERATION AS ASSESSED BY SWEPT SOURCE OPTICAL COHE[[REN]]CE TO[[MOG]]RAPHY.
|date=11.2020
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32111404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25874366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431381
|full-text-url=https://sci-hub.do/10.1097/IAE.0000000000000540
}}
}}
==EID3==
==VPS29==


* {{medline-title
* {{medline-title
|title=Upregulation of [[EID3]] sensitizes breast cancer cells to ionizing radiation-induced cellular senescence.
|title=Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development.
|date=11.2018
|date=16.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30114644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654520
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.08.022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359594
}}
}}
==EIF2B1==
* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=The retromer complex system in a transgenic mouse model of AD: influence of age.
|date=06.2018
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28110103
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2016.12.025
}}
}}
==EIF2B2==
==VPS35==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development.
|date=06.2018
|date=16.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654520
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359594
}}
}}
==EIF2B3==
* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis.
|date=06.2018
|date=11.02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24512632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016418
}}
}}
==EIF2B4==
==WFIKKN1==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.
|date=06.2018
|date=01.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188
}}
* {{medline-title
|title=A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28508553
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863538
}}
}}
==EIF2B5==
==WFIKKN2==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.
|date=06.2018
|date=01.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188
}}
* {{medline-title
|title=A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28508553
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863538
}}
}}
==EIF4E==
==WFS1==


* {{medline-title
* {{medline-title
|title=Transcriptomic evidence that insulin signalling pathway regulates the ageing of subterranean termite castes.
|title=Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila.
|date=18.05.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424344
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29357349
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794194
}}
}}
==ELANE==
* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=A nonsynonymous mutation in the [[WFS1]] gene in a Finnish family with age-related hearing impairment.
|date=13.11.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28974383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://sci-hub.do/10.1016/j.heares.2017.09.013
}}
}}
==ELF3==
==WIPI2==


* {{medline-title
* {{medline-title
|title=High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in [i]Arabidopsis[/i].
|title=Neuronal autophagy declines substantially with age and is rescued by overexpression of [[WIPI2]].
|date=31.07.2020
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32732458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398796
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984449
}}
}}
==ELL==
* {{medline-title
* {{medline-title
|title=Exceptional Longevity and Polygenic Risk for Cardiovascular Health.
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|date=18.03.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30889929
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471529
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
}}
}}
==ELOVL6==
==WNT16==


* {{medline-title
* {{medline-title
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|title=Inducible [i]Wnt16[/i] inactivation: [[WNT16]] regulates cortical bone thickness in adult mice.
|date=06.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29530924
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886037
}}
}}
==EML6==
* {{medline-title
* {{medline-title
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|title=Osteoblast-derived [[WNT16]] represses osteoclastogenesis and prevents cortical bone fragility fractures.
|date=07.2019
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25306233
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392888
}}
}}
==ENC1==
==WNT5A==


* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=[[WNT5A]] supports viability of senescent human dental follicle cells.
|date=05.2017
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30406314
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3467-9
}}
}}
==ENO1==
* {{medline-title
* {{medline-title
|title=Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells.
|title=The Ubiquitin-like with PHD and Ring Finger Domains 1 ([[UHRF1]])/DNA Methyltransferase 1 ([[DNMT1]]) Axis Is a Primary Regulator of Cell Senescence.
|date=2020
|date=03.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32355541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28100769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191177
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339756
}}
}}
==ENTPD7==
==WWP1==


* {{medline-title
* {{medline-title
|title=Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 ([[ENTPD7]]).
|title=The ubiquitin ligase [[WWP1]] contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart.
|date=23.08.2019
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31443651
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32822210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717125
}}
}}
==EPG5==
* {{medline-title
* {{medline-title
|title=Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom.
|title=Overexpression of miR-584-5p inhibits proliferation and induces apoptosis by targeting WW domain-containing E3 ubiquitin protein ligase 1 in gastric cancer.
|date=05.2018
|date=21.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28431583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401563
}}
}}
==EPHA1==
==XDH==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=Enhancing xanthine dehydrogenase activity is an effective way to delay leaf senescence and increase rice yield.
|date=16.08.2019
|date=11.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162142
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065298
}}
}}
==EPHA2==
* {{medline-title
* {{medline-title
|title=Germ-line and somatic [[EPHA2]] coding variants in lens aging and cataract.
|title=Pleurotus ostreatus, an edible mushroom, enhances glucose 6-phosphate dehydrogenase, ascorbate peroxidase and reduces xanthine dehydrogenase in major organs of aged rats.
|date=2017
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29267365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24392756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739433
|full-text-url=https://sci-hub.do/10.3109/13880209.2013.863948
}}
}}
==ERAP1==
==XRCC6==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Programmed Cell Death Genes Are Linked to Elevated Creatine Kinase Levels in Unhealthy Male Nonagenarians.
|date=10.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26913518
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993668
}}
}}
==ERBB4==
* {{medline-title
* {{medline-title
|title=Overexpression of [[ERBB4]] rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
|title=The impact of statins on biological characteristics of stem cells provides a novel explanation for their pleiotropic beneficial and adverse clinical effects.
|date=03.2019
|date=15.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26224580
|full-text-url=https://sci-hub.do/10.1096/fj.201801690R
|full-text-url=https://sci-hub.do/10.1152/ajpcell.00406.2014
}}
}}
==ERCC2==
==ZBTB16==


* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
|date=06.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
}}
* {{medline-title
|title=Determination phase at transition of gonocytes to spermatogonial stem cells improves establishment efficiency of spermatogonial stem cells in domestic cats.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26411537
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685225
}}
}}
==ERCC5==
==ZC3H12A==


* {{medline-title
* {{medline-title
|title=Identification of a [[ERCC5]] c.2333T>C (L778P) Variant in Two Tunisian Siblings With Mild Xeroderma Pigmentosum Phenotype.
|title=Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation.
|date=2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30838033
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31786670
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383105
|full-text-url=https://sci-hub.do/10.1007/s00109-019-01853-2
}}
* {{medline-title
|title=Prediction and characterization of human ageing-related proteins by using machine learning.
|date=06.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29511309
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840292
}}
}}
==ERCC6==
==ZEB2==


* {{medline-title
* {{medline-title
|title=Two Cockayne Syndrome patients with a novel splice site mutation - clinical and metabolic analyses.
|title=miR-200b regulates cellular senescence and inflammatory responses by targeting [[ZEB2]] in pulmonary emphysema.
|date=10.2018
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29944916
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32070140
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.001
|full-text-url=https://sci-hub.do/10.1080/21691401.2020.1725029
}}
* {{medline-title
|title=MicroRNA-145 induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by [[ZEB2]].
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30479019
|full-text-url=https://sci-hub.do/10.1002/jcp.27521
}}
}}
==ERCC8==
==ZNF521==


* {{medline-title
* {{medline-title
|title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.
|title=Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells.
|date=12.2019
|date=21.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31227697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588633
}}
}}
==ESPL1==
* {{medline-title
* {{medline-title
|title=Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants.
|title=Zinc finger factor 521 enhances adipogenic differentiation of mouse multipotent cells and human bone marrow mesenchymal stem cells.
|date=09.2020
|date=20.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32574725
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26008984
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461696
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558122
}}
}}
==ESR1==
==ZSCAN10==


* {{medline-title
* {{medline-title
|title=Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement.
|title=RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells.
|date=05.01.2018
|date=10.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020613
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788639
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639470
}}
}}
==ESRG==
* {{medline-title
* {{medline-title
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|title=[[ZSCAN10]] expression corrects the genomic instability of iPSCs from aged donors.
|date=10.04.2018
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846095
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843481
}}
}}
==ETV5==
==ABCC1==


* {{medline-title
* {{medline-title
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
|title=Dual pathways mediate β-amyloid stimulated glutathione release from astrocytes.
|date=06.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26200696
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
|full-text-url=https://sci-hub.do/10.1002/glia.22886
}}
}}
==ETV6==
==ABCC3==


* {{medline-title
* {{medline-title
|title=[[FOXO1]] and [[ETV6]] genes may represent novel regulators of splicing factor expression in cellular senescence.
|title=Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life.
|date=01.2019
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088951
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27103634
|full-text-url=https://sci-hub.do/10.1096/fj.201801154R
|full-text-url=https://sci-hub.do/10.1124/dmd.115.068577
}}
}}
==EVL==
==ABCE1==


* {{medline-title
* {{medline-title
|title=Health Years in Total: A New Health Objective Function for Cost-Effectiveness Analysis.
|title=Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain.
|date=01.2020
|date=27.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31952678
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485811
|full-text-url=https://sci-hub.do/10.1016/j.jval.2019.10.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354779
}}
}}
==EWSR1==
==ABCG1==


* {{medline-title
* {{medline-title
|title=[[EWSR1]], a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways.
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.
|date=01.07.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30481590
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770
}}
}}
==EXD2==
==ABCG5==


* {{medline-title
* {{medline-title
|title=[[EXD2]] governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation.
|title=2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms.
|date=02.2018
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29335528
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30939745
|full-text-url=https://sci-hub.do/10.1038/s41556-017-0016-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479705
}}
}}
==EXO1==
==ABHD12==


* {{medline-title
* {{medline-title
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|title=Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout [[ABHD12]] Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype.
|date=06.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31213981
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555221
}}
}}
==EXOC7==
==ABI3BP==


* {{medline-title
* {{medline-title
|title=[[PTBP1]]-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.
|title=Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing [[ABI3BP]] in gallbladder cancer cells.
|date=09.07.2018
|date=07.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990503
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174563
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555920
}}
}}
==EZR==
==ABL1==


* {{medline-title
* {{medline-title
|title=Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model.
|title=European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia.
|date=03.2018
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29245059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32127639
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214240
}}
}}
==F10==
==ABLIM3==


* {{medline-title
* {{medline-title
|title=Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-[[F10]] cells by inducing senescence.
|title=Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization.
|date=15.07.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097108
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29529016
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.06.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893385
}}
}}
==F12==
==ACAA2==


* {{medline-title
* {{medline-title
|title=Multigenerational effects of carbendazim in Daphnia magna: From a subcellular to a population level.
|title=p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria.
|date=02.2019
|date=10.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30508263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27059956
|full-text-url=https://sci-hub.do/10.1002/etc.4307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933453
}}
}}
==FA2H==
==ACAD9==


* {{medline-title
* {{medline-title
|title=C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production.
|title=Identification of a novel mitochondrial complex I assembly factor ACDH-12 in Caenorhabditis elegans.
|date=2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30184537
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428043
|full-text-url=https://sci-hub.do/10.1016/j.mito.2018.02.010
}}
}}
==FABP1==
==ACADM==


* {{medline-title
* {{medline-title
|title=Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken.
|title=High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats.
|date=01.09.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065718
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888352
|full-text-url=https://sci-hub.do/10.3382/ps/pez249
|full-text-url=https://sci-hub.do/10.1016/j.jfma.2017.08.008
}}
}}
==FADD==
==ACAT2==


* {{medline-title
* {{medline-title
|title=Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal [[FADD]].
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
|date=11.2018
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30138765
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.07.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823
}}
}}
==FADS1==
==ACKR2==


* {{medline-title
* {{medline-title
|title=Aging and [[FADS1]] polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U- C]linoleic acid.
|title=Atypical chemokine receptor [[ACKR2]] mediates chemokine scavenging by primary human trophoblasts and can regulate fetal growth, placental structure, and neonatal mortality in mice.
|date=09.2019
|date=15.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31492428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25297873
|full-text-url=https://sci-hub.do/10.1016/j.plefa.2019.07.003
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1401096
}}
}}
==FAH==
==ACMSD==


* {{medline-title
* {{medline-title
|title=Oxaloacetate decarboxylase [[FAH]]D1 - a new regulator of mitochondrial function and senescence.
|title=De novo NAD  synthesis enhances mitochondrial function and improves health.
|date=01.2019
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055189
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30356218
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.07.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448761
}}
}}
==FAHD1==
==ACP2==


* {{medline-title
* {{medline-title
|title=Oxaloacetate decarboxylase [[FAH]]D1 - a new regulator of mitochondrial function and senescence.
|title=Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-[[MADD]] locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=01.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055189
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951664
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.07.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066205
}}
}}
==FAM13A==
==ACSL5==


* {{medline-title
* {{medline-title
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease.
|title=Ageing sensitized by iPLA β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids.
|date=05.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2017.09.001
}}
}}
==FANCC==
==ACTA2==


* {{medline-title
* {{medline-title
|title=Fanconi Anemia complementation group C protein in metabolic disorders.
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|date=21.06.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29930218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046246
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
}}
}}
==FAR2==
==ACTL7B==


* {{medline-title
* {{medline-title
|title=[[FAR2]] is associated with kidney disease in mice and humans.
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|date=01.08.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29652635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
}}
}}
==FASN==
==ACTR3B==


* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|date=08.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
}}
}}
==FBN2==
==ADA2==


* {{medline-title
* {{medline-title
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging.
|title=Manganese(II) Chloride Alters Nucleotide and Nucleoside Catabolism in Zebrafish (Danio rerio) Adult Brain.
|date=26.10.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28547528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0601-8
}}
}}
==FBXO31==
==ADAM19==


* {{medline-title
* {{medline-title
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|title=[[ADAM19]] and [[HTR4]] variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=19.10.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136502
}}
}}
==FBXO46==
==ADAMTS1==


* {{medline-title
* {{medline-title
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|title=Increased [[ADAMTS1]] mediates [[SPARC]]-dependent collagen deposition in the aging myocardium.
|date=19.10.2018
|date=01.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27143554
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935141
}}
}}
==FCER1G==
==ADAMTS10==


* {{medline-title
* {{medline-title
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|title=Influence of Age on Ocular Biomechanical Properties in a Canine Glaucoma Model with [[ADAMTS10]] Mutation.
|date=2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27271467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894564
}}
}}
==FCGR2A==
==ADAMTS3==


* {{medline-title
* {{medline-title
|title=Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells.
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|date=03.08.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710049
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
}}
==FDPS==
==ADAMTS5==


* {{medline-title
* {{medline-title
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
|title=Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritis chondrocytes.
|date=12.2018
|date=16.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28728848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.07.094
}}
}}
==FER==
==ADAR==


* {{medline-title
* {{medline-title
|title=Tracking the recognition of static and dynamic facial expressions of emotion across the life span.
|title=Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis.
|date=04.09.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30208425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29986212
|full-text-url=https://sci-hub.do/10.1167/18.9.5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037660
}}
}}
==FER1L6==
==ADCK1==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Functional analysis of Aarf domain-containing kinase 1 in Drosophila melanogaster.
|date=12.2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175694
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271681
}}
}}
==FEZ1==
==ADD2==


* {{medline-title
* {{medline-title
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=19.09.2017
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==FGF6==
==ADK==


* {{medline-title
* {{medline-title
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|title=Deletion of pancreatic β-cell adenosine kinase improves glucose homeostasis in young mice and ameliorates streptozotocin-induced hyperglycaemia.
|date=06.02.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044530
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584724
}}
}}
==FGFR2==
==ADNP2==


* {{medline-title
* {{medline-title
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|date=10.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|full-text-url=https://sci-hub.do/10.1002/path.5314
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
}}
}}
==FKBP5==
==ADORA2B==


* {{medline-title
* {{medline-title
|title=Epigenetic upregulation of [[FKBP5]] by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk.
|title=Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss.
|date=04.06.2019
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113877
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33131093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561294
|full-text-url=https://sci-hub.do/10.1096/fj.202000939R
}}
}}
==FLT3==
==ADRA2A==


* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway.
|date=2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33116632
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574911
}}
}}
==FMO3==
==ADRM1==


* {{medline-title
* {{medline-title
|title=Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver.
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
|date=11.2017
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28819071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697103
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498
}}
}}
==FMR1==
==AGAP2==


* {{medline-title
* {{medline-title
|title=Static and dynamic postural control deficits in aging fragile X mental retardation 1 ([[FMR1]]) gene premutation carriers.
|title=Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating [[AGAP2]].
|date=21.01.2019
|date=05.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30665341
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386624
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341725
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710058
}}
}}
==FNTA==
==AGL==


* {{medline-title
* {{medline-title
|title=The Hip Morphology Changes with Ageing in Asian Population.
|title=Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis.
|date=2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30363710
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824446
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180959
|full-text-url=https://sci-hub.do/10.1136/bjsports-2014-094073
}}
}}
==FOSL2==
==AGO1==


* {{medline-title
* {{medline-title
|title=LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.
|title=A transcriptome-wide study on the microRNA- and the Argonaute 1-enriched small RNA-mediated regulatory networks involved in plant leaf senescence.
|date=03.04.2020
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32149459
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26206233
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132339
|full-text-url=https://sci-hub.do/10.1111/plb.12373
}}
}}
==FOXC1==
==AGRP==


* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Influence of Aging and Gender Differences on Feeding Behavior and Ghrelin-Related Factors during Social Isolation in Mice.
|date=15.04.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448274
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598162
}}
}}
==FOXD1==
==AHNAK==


* {{medline-title
* {{medline-title
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|title=A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging.
|date=12.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26457177
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600214
}}
}}
==FOXL2==
==AHSP==


* {{medline-title
* {{medline-title
|title=Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor.
|title=Relationship between Sensory Perception and Frailty in a Community-Dwelling Elderly Population.
|date=09.03.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29523193
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28537337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845161
|full-text-url=https://sci-hub.do/10.1007/s12603-016-0836-5
}}
}}
==FOXN1==
==AIF1==


* {{medline-title
* {{medline-title
|title=Thymic rejuvenation via [[FOXN1]]-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation.
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|date=17.09.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32790650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526556
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
}}
}}
==FOXP2==
==AK1==


* {{medline-title
* {{medline-title
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.
|title=The dominant negative [[AR]]M domain uncovers multiple functions of PUB13 in Arabidopsis immunity, flowering, and senescence.
|date=06.11.2018
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449551
}}
}}
==FOXP4==
==AKAP11==


* {{medline-title
* {{medline-title
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.
|title=Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II).
|date=06.11.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26821332
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247
|full-text-url=https://sci-hub.do/10.1159/000438900
}}
}}
==FRG1==
==AKAP12==


* {{medline-title
* {{medline-title
|title=Intergenerational response of steroidogenesis-related genes to maternal malnutrition.
|title=A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter.
|date=10.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789120
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29314444
|full-text-url=https://sci-hub.do/10.1017/S2040174419000060
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918158
}}
}}
==FRG2==
==AKAP17A==


* {{medline-title
* {{medline-title
|title=Intergenerational response of steroidogenesis-related genes to maternal malnutrition.
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|date=10.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789120
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|full-text-url=https://sci-hub.do/10.1017/S2040174419000060
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
}}
}}
==FSTL1==
==AKIP1==


* {{medline-title
* {{medline-title
|title=Blocking the [[FSTL1]]-[[DIP2A]] Axis Improves Anti-tumor Immunity.
|title=Expression of potato RNA-binding proteins StUBA2a/b and StUBA2c induces hypersensitive-like cell death and early leaf senescence in Arabidopsis.
|date=14.08.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30110636
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25944928
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.07.043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473998
}}
}}
==FZD4==
==AKR1B1==


* {{medline-title
* {{medline-title
|title=MiR-1292 Targets [[FZD4]] to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway.
|title=Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells.
|date=12.2018
|date=01.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27036204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818421
}}
}}
==G6PC==
==AKR1C2==


* {{medline-title
* {{medline-title
|title=Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of [[TP53]].
|title=Identification of a gene signature of a pre-transformation process by senescence evasion in normal human epidermal keratinocytes.
|date=11.2018
|date=14.06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24929818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106910
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065601
}}
}}
==G6PC3==
==AKR1C3==


* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=Identification of a gene signature of a pre-transformation process by senescence evasion in normal human epidermal keratinocytes.
|date=13.11.2018
|date=14.06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24929818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065601
}}
}}
==GAB2==
==AKR7A3==


* {{medline-title
* {{medline-title
|title=Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936.
|title=The aged testis. A good model to find proteins involved in age-related changes of testis by proteomic analysis.
|date=01.12.2017
|date=01-02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29207374
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24597284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764388
 
}}
}}
==GABARAP==
==AKT2==


* {{medline-title
* {{medline-title
|title=Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=18.08.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32811819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434891
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
==GADD45B==
==ALAD==


* {{medline-title
* {{medline-title
|title=Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging?
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.
|date=2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156709
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632
}}
}}
==GALC==
==ALAS1==


* {{medline-title
* {{medline-title
|title=Analysis of age-related changes in psychosine metabolism in the human brain.
|title=Heterozygous disruption of [[ALAS1]] in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver.
|date=2018
|date=08.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29481565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33307066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826537
|full-text-url=https://sci-hub.do/10.1016/j.abb.2020.108721
}}
}}
==GATA1==
==ALAS2==


* {{medline-title
* {{medline-title
|title=Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass.
|title=Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons.
|date=10.2019
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31299382
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26487704
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757025
}}
}}
==GATA6==
==ALDH1A1==


* {{medline-title
* {{medline-title
|title=GATA Regulation and Function During the Ovarian Life Cycle.
|title=Aldehyde Dehydrogenase 1 making molecular inroads into the differential vulnerability of nigrostriatal dopaminergic neuron subtypes in Parkinson's disease.
|date=2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544631
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25705376
|full-text-url=https://sci-hub.do/10.1016/bs.vh.2018.01.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334846
}}
}}
==GCAT==
==ALDH1L1==


* {{medline-title
* {{medline-title
|title=Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis.
|title=Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role.
|date=03.04.2018
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29551589
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27442752
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2018.02.004
|full-text-url=https://sci-hub.do/10.1111/nan.12338
}}
}}
==GCK==
==ALDH3A1==


* {{medline-title
* {{medline-title
|title=The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing.
|title=Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs).
|date=12.2019
|date=13.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31558549
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868460
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382415
}}
}}
==GCNT2==
==ALDOA==


* {{medline-title
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|date=18.03.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
}}
}}
==GDA==
==ALKBH1==


* {{medline-title
* {{medline-title
|title=Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces.
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|date=03.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436911
 
}}
}}
==GDF5==
==ALKBH2==


* {{medline-title
* {{medline-title
|title=An embryonic CaVβ1 isoform promotes muscle mass maintenance via [[GDF5]] signaling in adult mouse.
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|date=06.11.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31694926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aaw1131
}}
==GDF9==


* {{medline-title
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|date=18.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
}}
}}
==GEN1==
==ALOX12==


* {{medline-title
* {{medline-title
|title=US acculturation and poor sleep among an intergenerational cohort of adult Latinos in Sacramento, California.
|title=Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer.
|date=01.03.2019
|date=15.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30544165
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32265301
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242692
}}
}}
==GFRAL==
==ALOX5==


* {{medline-title
* {{medline-title
|title=Growth differentiation factor 15 ([[GDF15]]): A survival protein with therapeutic potential in metabolic diseases.
|title=Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme.
|date=06.2019
|date=01.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790643
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196666
|full-text-url=https://sci-hub.do/10.1089/ars.2019.7751
}}
}}
==GGCX==
==ALS2==


* {{medline-title
* {{medline-title
|title=Multiple Modes of Vitamin K Actions in Aging-Related Musculoskeletal Disorders.
|title=Age-dependent deterioration of locomotion in Drosophila melanogaster deficient in the homologue of amyotrophic lateral sclerosis 2.
|date=11.06.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31212662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24702731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600274
|full-text-url=https://sci-hub.do/10.1111/gtc.12146
}}
}}
==GHSR==
==AMBRA1==


* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=MiR-23a-depressed autophagy is a participant in PUVA- and UVB-induced premature senescence.
|date=06.2018
|date=21.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27191270
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122322
}}
}}
==GIT1==
==AMFR==


* {{medline-title
* {{medline-title
|title=[[GIT2]]-A keystone in ageing and age-related disease.
|title=Mice heterozygous for the Cdh23/Ahl1 mutation show age-related deficits in auditory temporal processing.
|date=05.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247458
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732241
}}
}}
==GJA8==
==AMHR2==


* {{medline-title
* {{medline-title
|title=The impact of [[GJA8]] SNPs on susceptibility to age-related cataract.
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|date=12.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30349978
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
}}
}}
==GJC2==
==ANGPT1==


* {{medline-title
* {{medline-title
|title=Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging.
|title=Altered microRNA expression in bovine skeletal muscle with age.
|date=10.2020
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32629311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25703017
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.04.017
|full-text-url=https://sci-hub.do/10.1111/age.12272
}}
}}
==GLA==
==ANGPT2==


* {{medline-title
* {{medline-title
|title=TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25.
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|date=17.05.2018
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769448
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012510
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
}}
}}
==GLI1==
==ANGPTL4==


* {{medline-title
* {{medline-title
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells.
|date=02.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x
}}
}}
==GLO1==
==ANGPTL8==


* {{medline-title
* {{medline-title
|title=The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases.
|title=Angiopoietin-like protein 8 ([[ANGPTL8]])/betatrophin overexpression does not increase beta cell proliferation in mice.
|date=2017
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29259621
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25917759
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473078
}}
}}
==GNAQ==
==ANK2==


* {{medline-title
* {{medline-title
|title=[[GNAQ]] expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=01.2020
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31680437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://sci-hub.do/10.1111/pcmr.12843
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==GNE==
==ANKS1B==


* {{medline-title
* {{medline-title
|title=Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2  mice.
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|date=10.12.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33300446
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|full-text-url=https://sci-hub.do/10.1080/15548627.2020.1850008
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
}}
==GNG4==
==ANPEP==


* {{medline-title
* {{medline-title
|title=Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for [[GNG4]] and [[KCNQ2]] Genes.
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity.
|date=05.2018
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338302
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174
}}
}}
==GNPAT==
==ANXA1==


* {{medline-title
* {{medline-title
|title=Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging.
|date=05.2019
|date=26.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30128650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1307-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848
}}
}}
==GORAB==
==AOX1==


* {{medline-title
* {{medline-title
|title=Examining tissue composition, whole-bone morphology and mechanical behavior of Gorab  mice tibiae: A mouse model of premature aging.
|title=N1-Methylnicotinamide: An Anti-Ovarian Aging Hormetin?
|date=08.12.2017
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29108851
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32711159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695220
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101131
}}
}}
==GOT1==
==APAF1==


* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|date=07.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
}}
}}
==GP1BA==
==APBB2==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension.
|date=15.11.2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26194614
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625986
}}
}}
==GP6==
==APLNR==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Endothelial [[APLNR]] regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.
|date=15.11.2018
|date=13.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904225
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703224
}}
}}
==GPBAR1==
==APOA4==


* {{medline-title
* {{medline-title
|title=Activation of the bile acid receptor [[GPBAR1]] (TGR5) ameliorates interleukin-1β (IL-1β)- induced chondrocytes senescence.
|title=No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes.
|date=10.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946122
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.06.154
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709
}}
}}
==GPC1==
==APOBEC1==


* {{medline-title
* {{medline-title
|title=Decreased expression of [[GPC1]] in human skin keratinocytes and epidermis during ageing.
|title=Loss of [[APOBEC1]] RNA-editing function in microglia exacerbates age-related CNS pathophysiology.
|date=15.10.2019
|date=12.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31430521
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167375
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740644
}}
}}
==GPD2==
==APOC1==


* {{medline-title
* {{medline-title
|title=Switching off [[IMMP2L]] signaling drives senescence via simultaneous metabolic alteration and blockage of cell death.
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|date=06.2018
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993829
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
}}
}}
==GPR101==
==APOC2==


* {{medline-title
* {{medline-title
|title=Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent.
|title=Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia.
|date=2017
|date=01.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26044956
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527288
}}
}}
==GPR158==
==APOD==


* {{medline-title
* {{medline-title
|title=RbAp48 Protein Is a Critical Component of [[GPR158]]/OCN Signaling and Ameliorates Age-Related Memory Loss.
|title=Apolipoprotein D takes center stage in the stress response of the aging and degenerative brain.
|date=23.10.2018
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355501
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24612673
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988949
}}
}}
==GPR173==
==APOH==


* {{medline-title
* {{medline-title
|title=Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent.
|title=Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults.
|date=2017
|date=31.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27030319
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814826
}}
}}
==GPR19==
==APPL1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Insulin and adipokine signaling and their cross-regulation in postmortem human brain.
|date=15.11.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31539648
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960343
}}
}}
==GPR37==
==AQP2==


* {{medline-title
* {{medline-title
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|title=A bell-shaped pattern of urinary aquaporin-2-bearing extracellular vesicle release in an experimental model of nephronophthisis.
|date=08.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074077
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509436
}}
}}
==GPR37L1==
==AQP9==


* {{medline-title
* {{medline-title
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|title=Seasonal and Ageing-Depending Changes of Aquaporins 1 and 9 Expression in the Genital Tract of Buffalo Bulls (Bubalus bubalis).
|date=08.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27260501
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
|full-text-url=https://sci-hub.do/10.1111/rda.12713
}}
}}
==GPR6==
==AQR==


* {{medline-title
* {{medline-title
|title=Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy.
|title=Synergism between soluble guanylate cyclase signaling and neuropeptides extends lifespan in the nematode Caenorhabditis elegans.
|date=22.09.2020
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32959881
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28054425
|full-text-url=https://sci-hub.do/10.1093/infdis/jiaa599
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334569
}}
}}
==GPX2==
==ARG1==


* {{medline-title
* {{medline-title
|title=RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells.
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=10.10.2017
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020613
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639470
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
==GPX3==
==ARG2==


* {{medline-title
* {{medline-title
|title=Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract.
|title=Arginase-2, a miR-1299 target, enhances pigmentation in melasma by reducing melanosome degradation via senescence-induced autophagy inhibition.
|date=2019
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814699
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28627081
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857780
|full-text-url=https://sci-hub.do/10.1111/pcmr.12605
}}
}}
==GPX7==
==ARHGAP1==


* {{medline-title
* {{medline-title
|title=Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7.
|title=Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study.
|date=08.2018
|date=01.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27616567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837042
}}
}}
==GRB10==
==ARID5A==


* {{medline-title
* {{medline-title
|title=De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver.
|title=Differentially regulated gene expression in quiescence versus senescence and identification of [[ARID5A]] as a quiescence associated marker.
|date=05.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29044508
|full-text-url=https://sci-hub.do/10.1530/JME-18-0018
|full-text-url=https://sci-hub.do/10.1002/jcp.26227
}}
}}
==GRB2==
==ARIH2==


* {{medline-title
* {{medline-title
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice.
|title=A novel feed-forward loop between [[ARIH2]] E3-ligase and [[PABPN1]] regulates aging-associated muscle degeneration.
|date=21.01.2019
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24486325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397
|full-text-url=https://sci-hub.do/10.1016/j.ajpath.2013.12.011
}}
}}
==GREM1==
==ARL13B==


* {{medline-title
* {{medline-title
|title=[[GREM1]] inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells.
|title=[[ARL13B]], a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments.
|date=09.03.2020
|date=20.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573647
|full-text-url=https://sci-hub.do/10.1080/03008207.2020.1736054
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381253
}}
}}
==GREM2==
==ARNTL==


* {{medline-title
* {{medline-title
|title=Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=12.2019
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31709279
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831850
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
==GRID1==
==ARNTL2==


* {{medline-title
* {{medline-title
|title=Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=03.2020
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2020.02.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
==GRIN2B==
==ARRB2==


* {{medline-title
* {{medline-title
|title=Medial temporal lobe atrophy relates more strongly to sleep-wake rhythm fragmentation than to age or any other known risk.
|title=Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity.
|date=04.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29864525
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304635
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2018.05.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801044
}}
}}
==GRK4==
==ARSA==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=15.11.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==GRK6==
==ASB3==


* {{medline-title
* {{medline-title
|title=Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity.
|title=Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.
|date=12.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818258
}}
}}
==GRM2==
==ASB7==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=[[ASB7]] Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation.
|date=11.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33251222
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674779
}}
}}
==GRM3==
==ASIP==


* {{medline-title
* {{medline-title
|title=Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk.
|title=Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation.
|date=04.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32203495
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222197
|full-text-url=https://sci-hub.do/10.1038/s41593-020-0604-z
|full-text-url=https://sci-hub.do/10.1111/ics.12494
}}
}}
==GSN==
==ASMT==


* {{medline-title
* {{medline-title
|title=Oral administration of alcalase potato protein hydrolysate-APPH attenuates high fat diet-induced cardiac complications via TGF-β/[[GSN]] axis in aging rats.
|title=The influence of ageing on the extrapineal melatonin synthetic pathway.
|date=01.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30240538
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29906492
|full-text-url=https://sci-hub.do/10.1002/tox.22651
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.06.010
}}
}}
==GSTA1==
==ASPN==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=The association between higher social support and lower depressive symptoms among aging services clients is attenuated at higher levels of functional impairment.
|date=12.2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25663607
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527957
}}
}}
==GSTK1==
==ATG10==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Genetic associations with age of menopause in familial longevity.
|date=12.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==GSTM2==
==ATG13==


* {{medline-title
* {{medline-title
|title=Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage.
|title=Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autophagy, in the liver of middle-aged mice.
|date=07.07.2020
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32574561
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27498120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342013
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.08.002
}}
==ATG16L1==
 
* {{medline-title
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
}}
}}
==GSTM3==
==ATG16L2==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats.
|date=12.2018
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286171
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501279
}}
}}
==GSTO1==
==ATG4B==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Impaired autophagic activity and [[ATG4B]] deficiency are associated with increased endoplasmic reticulum stress-induced lung injury.
|date=12.2018
|date=27.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30147026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128419
}}
}}
==GSTP1==
==ATG4D==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats.
|date=12.2018
|date=17.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b02567
}}
}}
==GSTT1==
==ATMIN==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Perturbed hematopoiesis in mice lacking [[ATM]]IN.
|date=12.2018
|date=20.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27581360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147016
}}
}}
==GSTT2==
==ATOH1==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=In Vivo Interplay between p27 , [[GATA3]], [[ATOH1]], and [[POU4F3]] Converts Non-sensory Cells to Hair Cells in Adult Mice.
|date=12.2018
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28402854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423718
}}
}}
==GSTZ1==
==ATP1A3==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=The Influence of Na( ), K( )-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence.
|date=12.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27313535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890531
}}
}}
==GUK1==
==ATP2B1==


* {{medline-title
* {{medline-title
|title=Characterization of the impact of GMP/GDP synthesis inhibition on replicative lifespan extension in yeast.
|title=Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries.
|date=08.2020
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32232569
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28795531
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367712
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595685
}}
}}
==GYS2==
==ATP6V0C==


* {{medline-title
* {{medline-title
|title=In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers.
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|date=04.2018
|date=07.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986936
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|full-text-url=https://sci-hub.do/10.1111/jpn.12831
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
}}
}}
==GZMK==
==ATP6V1G1==


* {{medline-title
* {{medline-title
|title=Comprehensive Profiling of an Aging Immune System Reveals Clonal [[GZMK]] CD8  T Cells as Conserved Hallmark of Inflammaging.
|title=Chemical screening identifies [[ATM]] as a target for alleviating senescence.
|date=21.11.2020
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33271118
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28346404
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2020.11.005
|full-text-url=https://sci-hub.do/10.1038/nchembio.2342
}}
}}
==HADHA==
==ATXN1==


* {{medline-title
* {{medline-title
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
}}
==HAMP==
==ATXN3==


* {{medline-title
* {{medline-title
|title=A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity.
|title=Rescue of [[ATXN3]] neuronal toxicity in [i]Caenorhabditis[/i][i]elegans[/i] by chemical modification of endoplasmic reticulum stress.
|date=04.2018
|date=19.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29408220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29061563
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.01.044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769603
}}
}}
==HAP1==
==AURKA==


* {{medline-title
* {{medline-title
|title=The longevity SNP rs2802292 uncovered: [[HSF1]] activates stress-dependent expression of [[FOXO3]] through an intronic enhancer.
|title=Combined therapies that induce senescence and stabilize p53 block melanoma growth and prompt antitumor immune responses.
|date=20.06.2018
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733381
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26405565
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009585
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570092
}}
}}
==HAS2==
==AVPR1A==


* {{medline-title
* {{medline-title
|title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts.
|title=Introduction of the human [[AVPR1A]] gene substantially alters brain receptor expression patterns and enhances aspects of social behavior in transgenic mice.
|date=01.2018
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24924430
|full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107330
}}
}}
==HAX1==
==BAALC==


* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=Relation of [[BAALC]] and [[ERG]] Gene Expression with Overall Survival in Acute Myeloid Leukemia Cases.
|date=13.11.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26625814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://sci-hub.do/10.7314/apjcp.2015.16.17.7875
}}
}}
==HBD==
==BACE2==


* {{medline-title
* {{medline-title
|title=Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection.
|title=Lessons from a [[BACE1]] inhibitor trial: off-site but not off base.
|date=2019
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026271
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24530026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205206
}}
}}
==HBM==
==BACH2==


* {{medline-title
* {{medline-title
|title=The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis.
|title=Age-related changes in the [[BACH2]] and [[PRDM1]] genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.
|date=25.09.2019
|date=17.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31553309
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337793
}}
}}
==HCN4==
==BAG2==


* {{medline-title
* {{medline-title
|title=Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels.
|title=[[BAG2]] Interferes with CHIP-Mediated Ubiquitination of HSP72.
|date=05.2018
|date=30.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288034
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28042827
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297704
}}
}}
==HCRT==
==BAP1==


* {{medline-title
* {{medline-title
|title=Age-related central regulation of orexin and [[NPY]] in the short-lived African killifish Nothobranchius furzeri.
|title=The [[BAP1]]/[[ASXL2]] Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.
|date=15.05.2019
|date=27.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666646
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416890
|full-text-url=https://sci-hub.do/10.1002/cne.24638
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661380
}}
}}
==HDAC10==
==BAZ1A==


* {{medline-title
* {{medline-title
|title=Middle-aged female rats lack changes in histone H3 acetylation in the anterior hypothalamus observed in young females on the day of a luteinizing hormone surge.
|title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells.
|date=17.09.2019
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31434815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244
|full-text-url=https://sci-hub.do/10.5582/bst.2019.01162
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023
}}
}}
==HDAC11==
==BAZ2B==


* {{medline-title
* {{medline-title
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|title=Two conserved epigenetic regulators prevent healthy ageing.
|date=19.09.2017
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32103178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2037-y
}}
}}
==HDAC8==
==BBS5==


* {{medline-title
* {{medline-title
|title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.
|title=Progressive Characterization of Visual Phenotype in Bardet-Biedl Syndrome Mutant Mice.
|date=09.2018
|date=01.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30901771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771
|full-text-url=https://sci-hub.do/10.1167/iovs.18-25210
}}
}}
==HDC==
==BCAS1==


* {{medline-title
* {{medline-title
|title=Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells.
|title=Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs).
|date=07.05.2020
|date=13.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760648
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.02.092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382415
}}
}}
==HES1==
==BCL2L1==


* {{medline-title
* {{medline-title
|title=A Single-Cell Transcriptomic Atlas of Human Skin Aging.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=23.11.2020
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33238152
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2020.11.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==HHLA2==
==BCL2L11==


* {{medline-title
* {{medline-title
|title=Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma.
|title=miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence.
|date=05.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30768970
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074095
|full-text-url=https://sci-hub.do/10.1016/j.jtho.2019.01.024
|full-text-url=https://sci-hub.do/10.1002/jcb.28862
}}
}}
==HIF1A==
==BCORL1==


* {{medline-title
* {{medline-title
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|title=Age-related mutations associated with clonal hematopoietic expansion and malignancies.
|date=07.2018
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25326804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313872
}}
}}
==HIF3A==
==BFSP1==


* {{medline-title
* {{medline-title
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|title=The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling.
|date=07.2018
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28177569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334568
}}
}}
==HIRA==
==BHLHE40==


* {{medline-title
* {{medline-title
|title=Pak2 kinase promotes cellular senescence and organismal aging.
|title=Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1.
|date=02.07.2019
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31209047
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32360904
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613284
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105689
}}
}}
==HJV==
==BICD1==


* {{medline-title
* {{medline-title
|title=Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting.
|title=Kidney Allograft Telomere Length Is Not Associated with Sex, Recipient Comorbid Conditions, Post-Transplant Infections, or CMV Reactivation.
|date=06.2019
|date=28.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884219
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27350315
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596404
|full-text-url=https://sci-hub.do/10.12659/aot.898007
}}
}}
==HK2==
==BMP1==


* {{medline-title
* {{medline-title
|title=Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury.
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells.
|date=11.01.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811244
|full-text-url=https://sci-hub.do/10.1071/RD14472
}}
}}
==HLA-DMA==
==BMP5==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=[[BMP5]] expression in the adult rat brain.
|date=10.2019
|date=22.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25110111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2014.07.057
}}
}}
==HLA-DPA1==
==BMX==


* {{medline-title
* {{medline-title
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|title=Inducible Activation of [[FGFR2]] in Adult Mice Promotes Bone Formation After Bone Marrow Ablation.
|date=09.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28650109
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
|full-text-url=https://sci-hub.do/10.1002/jbmr.3204
}}
}}
==HLA-DQA1==
==BNC1==


* {{medline-title
* {{medline-title
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|date=09.2019
|date=22.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
}}
}}
==HLA-DQB1==
==BNC2==


* {{medline-title
* {{medline-title
|title=Identification of new genetic variants of [[HLA-DQB1]] associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population.
|title=Genetic variants associated with skin aging in the Chinese Han population.
|date=10.11.2017
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129831
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28057405
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723689
|full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2016.12.017
}}
}}
==HLA-DRB1==
==BOC==


* {{medline-title
* {{medline-title
|title=The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle.
|title=Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations.
|date=11.2020
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32942037
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32140711
|full-text-url=https://sci-hub.do/10.1016/j.autrev.2020.102670
|full-text-url=https://sci-hub.do/10.1093/jn/nxaa031
}}
}}
==HLA-E==
==BOK==


* {{medline-title
* {{medline-title
|title=Senescent cells evade immune clearance via [[HLA-E]]-mediated NK and CD8  T cell inhibition.
|title=Comparative proteomic analysis of primordial follicles from ovaries of immature and aged rats.
|date=03.06.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160572
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391928
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547655
|full-text-url=https://sci-hub.do/10.3109/19396368.2015.1077903
}}
}}
==HMGA1==
==BRD3==


* {{medline-title
* {{medline-title
|title=Characterization of [i][[HMGA1]]P6[/i] transgenic mouse embryonic fibroblasts.
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke.
|date=09.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32787507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513866
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004
}}
}}
==HMGCS1==
==BRD7==


* {{medline-title
* {{medline-title
|title=The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
|title=[[XIAP]]-associating factor 1, a transcriptional target of [[BRD7]], contributes to endothelial cell senescence.
|date=15.10.2018
|date=02.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802028
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.08.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868675
}}
}}
==HNF4A==
==BRINP1==


* {{medline-title
* {{medline-title
|title=Hepatocyte Nuclear Factor-4α P2 Promoter Variants Are Associated With the Risk of Metabolic Syndrome and Testosterone Deficiency in Aging Taiwanese Men.
|title=Absence of [[BRINP1]] in mice causes increase of hippocampal neurogenesis and behavioral alterations relevant to human psychiatric disorders.
|date=11.2018
|date=14.02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415809
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24528488
|full-text-url=https://sci-hub.do/10.1016/j.jsxm.2018.09.012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928644
}}
}}
==HNRNPA0==
==BTG1==


* {{medline-title
* {{medline-title
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|title=Tumor cell escape from therapy-induced senescence.
|date=10.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576620
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
|full-text-url=https://sci-hub.do/10.1016/j.bcp.2018.12.013
}}
}}
==HNRNPA1==
==BTG3==


* {{medline-title
* {{medline-title
|title=[[HNRNPA1]]-mediated 3' UTR length changes of [i]HN1[/i] contributes to cancer- and senescence-associated phenotypes.
|title=Investigating the specific core genetic-and-epigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells.
|date=30.06.2019
|date=23.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26895224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890987
}}
}}
==HNRNPM==
==BTG4==


* {{medline-title
* {{medline-title
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|title=Age-related decrease of IF5/[[BTG4]] in oral and respiratory cavities in mice.
|date=10.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25660503
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
|full-text-url=https://sci-hub.do/10.1080/09168451.2015.1008976
}}
}}
==HOXA3==
==BUB1==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Links between nucleolar activity, rDNA stability, aneuploidy and chronological aging in the yeast Saccharomyces cerevisiae.
|date=25.07.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24711086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019837
}}
}}
==HOXA4==
==C1QA==


* {{medline-title
* {{medline-title
|title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes.
|title=[[APOE]] Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction.
|date=10.2019
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26512759
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626092
}}
}}
==HOXB7==
==C2CD2==


* {{medline-title
* {{medline-title
|title=Impact of [[HOXB7]] overexpression on human adipose-derived mesenchymal progenitors.
|title=Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort.
|date=19.03.2019
|date=20.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29158487
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423808
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696534
}}
}}
==HOXC4==
==C4A==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=Investigation of complement component C4 copy number variation in human longevity.
|date=11.2017
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24465950
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899116
}}
}}
==HOXD8==
==C4B==


* {{medline-title
* {{medline-title
|title=Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts.
|title=Investigation of complement component C4 copy number variation in human longevity.
|date=2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849838
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24465950
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431633
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899116
}}
}}
==HPD==
==C8orf48==


* {{medline-title
* {{medline-title
|title=Protein-Amino Acid Metabolism Disarrangements: The Hidden Enemy of Chronic Age-Related Conditions.
|title=Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model.
|date=22.03.2018
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29565819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24496748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946176
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209016
}}
}}
==HPSE==
==CABLES1==


* {{medline-title
* {{medline-title
|title=Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin.
|title=[[CABLES1]] Deficiency Impairs Quiescence and Stress Responses of Hematopoietic Stem Cells in Intrinsic and Extrinsic Manners.
|date=07.2020
|date=13.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32159248
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327733
|full-text-url=https://sci-hub.do/10.1002/cbin.11339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700604
}}
}}
==HRG==
==CACNA1B==


* {{medline-title
* {{medline-title
|title=Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=10.2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29021712
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==HRH4==
==CACNA1C==


* {{medline-title
* {{medline-title
|title=Histamime Receptor H4 as a New Therapeutic Target for Age-related Macular Degeneration.
|title=Epigenetic regulation of L-type voltage-gated Ca  channels in mesenteric arteries of aging hypertensive rats.
|date=11.2016
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30074739
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27881847
|full-text-url=https://sci-hub.do/10.1038/hr.2016.167
}}
==CACNA1F==


* {{medline-title
|title=Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics.
|date=08.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27267879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897877
}}
}}
==HS2ST1==
==CACNA1S==


* {{medline-title
* {{medline-title
|title=Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity.
|title=Increased calcium channel in the lamina propria of aging rat.
|date=31.01.2020
|date=31.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31940721
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31682233
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999708
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834399
}}
}}
==HSD17B14==
==CACNA2D1==


* {{medline-title
* {{medline-title
|title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts.
|title=Pregabalin can prevent, but not treat, cognitive dysfunction following abdominal surgery in aged rats.
|date=04.2018
|date=01.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26872983
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2016.02.021
}}
}}
==HSD17B4==
==CADM2==


* {{medline-title
* {{medline-title
|title=Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein-2 deficiency.
|title=GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
|date=09.2018
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29341299
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25199915
|full-text-url=https://sci-hub.do/10.1111/bpa.12586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296168
}}
}}
==HSD3B2==
==CALHM1==


* {{medline-title
* {{medline-title
|title=11-Oxygenated C19 Steroids Do Not Decline With Age in Women.
|title=[[CALHM1]] Deletion in Mice Affects Glossopharyngeal Taste Responses, Food Intake, Body Weight, and Life Span.
|date=01.07.2019
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25855639
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525564
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542651
}}
}}
==HSP90AA1==
==CALR==


* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender.
|date=09.2017
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0
}}
}}
==HSPA13==
==CAMP==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=[Study on effect of astragali radix polysaccharides in improving learning and memory functions in aged rats and its mechanism].
|date=10.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25272845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
==HSPA1L==


* {{medline-title
|title=Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the [[HSPA1L]]-mitophagy pathway.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31965731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059143
}}
}}
==HSPA5==
==CAMSAP1==


* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|date=08.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
}}
}}
==HSPB1==
==CAP2==


* {{medline-title
* {{medline-title
|title=The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity.
|title=Targeting MRTF/[[SRF]] in [[CAP2]]-dependent dilated cardiomyopathy delays disease onset.
|date=06.2019
|date=21.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102684
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30762586
|full-text-url=https://sci-hub.do/10.1016/j.diabres.2019.05.009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483011
}}
}}
==HSPB6==
==CAPN1==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Defects in the [[CAPN1]] Gene Result in Alterations in Cerebellar Development and Cerebellar Ataxia in Mice and Humans.
|date=2019
|date=28.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27320912
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927383
}}
}}
==HSPG2==
==CAPRIN1==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Reduced Levels of the Synaptic Functional Regulator FMRP in Dentate Gyrus of the Aging Sprague-Dawley Rat.
|date=02.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29218006
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703695
}}
}}
==HTRA1==
==CARD14==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Elderly-Onset Generalized Pustular Psoriasis without a Previous History of Psoriasis Vulgaris.
|date=06.2018
|date=05-08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26351429
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560317
}}
}}
==HYOU1==
==CASP1==


* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age.
|date=08.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448778
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596365
}}
}}
==IAPP==
==CASP5==


* {{medline-title
* {{medline-title
|title=Protein aggregates and proteostasis in aging: Amylin and β-cell function.
|title=Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age.
|date=01.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580826
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448778
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.03.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596365
}}
}}
==ICAM1==
==CASP7==


* {{medline-title
* {{medline-title
|title=An Inhibitor of Activated Blood Coagulation Factor X Shows Anti-Endothelial Senescence and Anti-Atherosclerotic Effects.
|title=Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence.
|date=2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31266015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26029164
|full-text-url=https://sci-hub.do/10.1159/000499975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432801
}}
}}
==ICE1==
==CASQ2==


* {{medline-title
* {{medline-title
|title=ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1.
|title=Single delivery of an adeno-associated viral construct to transfer the [[CASQ2]] gene to knock-in mice affected by catecholaminergic polymorphic ventricular tachycardia is able to cure the disease from birth to advanced age.
|date=19.02.2020
|date=24.06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24888331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031079
|full-text-url=https://sci-hub.do/10.1161/CIRCULATIONAHA.113.006901
}}
}}
==ID2==
==CAV1==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine.
|date=10.2019
|date=24.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30690072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.1016/j.jep.2019.01.019
}}
}}
==IFI27==
==CBSL==


* {{medline-title
* {{medline-title
|title=Ultraviolet B irradiation-induced keratinocyte senescence and impaired development of 3D epidermal reconstruct.
|title=Effect of a Community-Based Service Learning Experience in Geriatrics on Internal Medicine Residents and Community Participants.
|date=01.06.2021
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33151171
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28734046
|full-text-url=https://sci-hub.do/10.2478/acph-2021-0011
|full-text-url=https://sci-hub.do/10.1111/jgs.14968
}}
}}
==IFIH1==
==CBX3==


* {{medline-title
* {{medline-title
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|title=Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development.
|date=03.2018
|date=24.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32979540
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
|full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115659
}}
}}
==IFIT1==
==CBX4==


* {{medline-title
* {{medline-title
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|title=Maintenance of Nucleolar Homeostasis by [[CBX4]] Alleviates Senescence and Osteoarthritis.
|date=06.2018
|date=26.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30917318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.02.088
}}
}}
==IFITM1==
==CBX5==


* {{medline-title
* {{medline-title
|title=Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection.
|title=The Ubiquitin-like with PHD and Ring Finger Domains 1 ([[UHRF1]])/DNA Methyltransferase 1 ([[DNMT1]]) Axis Is a Primary Regulator of Cell Senescence.
|date=10.11.2018
|date=03.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878083
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28100769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339756
}}
==CCAR2==
 
* {{medline-title
|title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500
}}
}}
==IFITM3==
==CCDC102B==


* {{medline-title
* {{medline-title
|title=Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein [[IFITM3]].
|title=Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system.
|date=25.06.2019
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27337627
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613042
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2016.06.005
}}
}}
==IFNG==
==CCDC17==


* {{medline-title
* {{medline-title
|title=Glutathione Peroxidase 3 Delivered by hiPSC-[[MSC]]s Ameliorated Hepatic IR Injury via Inhibition of Hepatic Senescence.
|title=Aberrant DNA Methylation in Keratoacanthoma.
|date=2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29290803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27788211
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743470
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082942
}}
}}
==IFT140==
==CCDC71L==


* {{medline-title
* {{medline-title
|title=The Role of [[IFT140]] in Osteogenesis of Adult Mice Long Bone.
|title=Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=08.2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31034313
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951662
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112104
}}
}}
==IGF2BP3==
==CCDC88A==


* {{medline-title
* {{medline-title
|title=Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=01.05.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888162
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b00833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==IGF2R==
==CCL1==


* {{medline-title
* {{medline-title
|title=Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks.
|title=[Peptides and [[[[CCL1]]1]] and [[HMGB1]] as molecular markers of aging: literature review and own data].
|date=05-06.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29554514
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826983
|full-text-url=https://sci-hub.do/10.1016/j.archger.2018.03.004
 
}}
}}
==IGFBP4==
==CCL18==


* {{medline-title
* {{medline-title
|title=Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey.
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|date=11.10.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31601169
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788010
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
}}
}}
==IGFBP6==
==CCL26==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state.
|date=02.2018
|date=11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24759206
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205198
}}
}}
==IGFBP7==
==CCL28==


* {{medline-title
* {{medline-title
|title=Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7.
|title=Age-related chemokine alterations affect IgA secretion and gut immunity in female mice.
|date=03.2020
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31904196
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32277312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031646
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09877-9
}}
}}
==IGHD==
==CCL7==


* {{medline-title
* {{medline-title
|title=Growth Hormone Deficiency: Health and Longevity.
|title=Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension.
|date=01.04.2019
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28017665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416709
|full-text-url=https://sci-hub.do/10.1016/j.phrs.2016.12.032
}}
}}
==IGSF1==
==CCL8==


* {{medline-title
* {{medline-title
|title=Age-related gene and miRNA expression changes in airways of healthy individuals.
|title=Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists.
|date=06.03.2019
|date=15.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28696254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548610
}}
}}
==IHH==
==CCM2==


* {{medline-title
* {{medline-title
|title=Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway.
|title=Vascular permeability in cerebral cavernous malformations.
|date=01.04.2020
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32235006
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25966944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185126
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640319
}}
}}
==IKBKB==
==CCNA1==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
|date=02.2019
|date=02.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654
}}
}}
==IL13==
==CCND2==


* {{medline-title
* {{medline-title
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|title=Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma.
|date=07.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097674
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135677
}}
}}
==IL15==
==CCND3==


* {{medline-title
* {{medline-title
|title=Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of [[IL15]].
|title=The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells.
|date=27.04.2020
|date=29.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32221610
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32727592
|full-text-url=https://sci-hub.do/10.1093/ageing/afaa035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392710
}}
}}
==IL17RA==
==CCR1==


* {{medline-title
* {{medline-title
|title=Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon.
|title=Myocardial Infarction Superimposed on Aging: MMP-9 Deletion Promotes M2 Macrophage Polarization.
|date=2017
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039977
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25878031
|full-text-url=https://sci-hub.do/10.1080/07420528.2017.1361436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175450
}}
}}
==IL18==
==CCR10==


* {{medline-title
* {{medline-title
|title=Aging and the Inflammasomes.
|title=Cardiac aging is initiated by matrix metalloproteinase-9-mediated endothelial dysfunction.
|date=2018
|date=15.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30536177
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24658018
|full-text-url=https://sci-hub.do/10.1007/978-3-319-89390-7_13
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024719
}}
}}
==IL1R2==
==CCR9==


* {{medline-title
* {{medline-title
|title=Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin.
|title=Attenuation of migration properties of CD4  T cells from aged mice correlates with decrease in chemokine receptor expression, response to retinoic acid, and RALDH expression compared to young mice.
|date=01.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28777886
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25036122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721243
|full-text-url=https://sci-hub.do/10.1080/09168451.2014.910099
}}
}}
==IL22==
==CCT8==


* {{medline-title
* {{medline-title
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|title=Somatic increase of [[CCT8]] mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan.
|date=07.2019
|date=28.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27892468
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133698
}}
}}
==IL2RA==
==CD209==


* {{medline-title
* {{medline-title
|title=Dynamic demethylation of the [[IL2RA]] promoter during in vitro CD4+ T cell activation in association with [[IL2RA]] expression.
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|date=2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30096258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
}}
}}
==IL4==
==CD226==


* {{medline-title
* {{medline-title
|title=Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia.
|title=T-cell Immunoglobulin and ITIM Domain Contributes to CD8  T-cell Immunosenescence.
|date=01.01.2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122767
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29349889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756472
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847879
}}
}}
==IL6ST==
==CD3G==


* {{medline-title
* {{medline-title
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|title=Phenotypic characteristics of aged [[CD4]] [[CD28]]  T lymphocytes are determined by changes in the whole-genome DNA methylation pattern.
|date=06.2019
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28026094
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334526
}}
}}
==IL9==
==CD48==


* {{medline-title
* {{medline-title
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|title=Genetic overexpression of [[COMP]]-Ang1 impairs BM microenvironment and induces senescence of BM HSCs.
|date=08.2019
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.210
}}
}}
==ILDR1==
==CD55==


* {{medline-title
* {{medline-title
|title=Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment.
|title=Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia.
|date=23.10.2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31645637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303009
}}
}}
==IMMP2L==
==CD59==


* {{medline-title
* {{medline-title
|title=Switching off [[IMMP2L]] signaling drives senescence via simultaneous metabolic alteration and blockage of cell death.
|title=Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria.
|date=06.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993829
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529780
}}
}}
==ING1==
==CD6==


* {{medline-title
* {{medline-title
|title=Impaired DNA demethylation of C/EBP sites causes premature aging.
|title=Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures.
|date=01.06.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29884649
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27249102
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931852
}}
}}
==INHBA==
==CD72==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation.
|date=02.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930899
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428705
}}
}}
==INHBE==
==CD82==


* {{medline-title
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|title=Cell-surface phenotyping identifies [[CD36]] and CD97 as novel markers of fibroblast quiescence in lung fibrosis.
|date=18.03.2019
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
|full-text-url=https://sci-hub.do/10.1152/ajplung.00439.2017
}}
}}
==INPP4B==
==CD83==


* {{medline-title
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|title=Human mesothelioma induces defects in dendritic cell numbers and antigen-processing function which predict survival outcomes.
|date=04.2016
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27057464
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801471
}}
}}
==INPP5A==
==CDC20==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Premature aging syndrome showing random chromosome number instabilities with [[CDC20]] mutation.
|date=25.07.2018
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33094908
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681047
}}
}}
==IP6K1==
==CDC6==


* {{medline-title
* {{medline-title
|title=The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle.
|title=A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.
|date=2019
|date=10.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552262
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29321003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746962
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763532
}}
}}
==IPMK==
==CDC73==


* {{medline-title
* {{medline-title
|title=Inositol Polyphosphate Multikinase ([i][[IPMK]][/i]), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity.
|title=Down-regulation of cancer-associated gene [[CDC73]] contributes to cellular senescence.
|date=08.02.2019
|date=23.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30744060
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29621547
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410091
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.228
}}
}}
==IRF1==
==CDCA3==


* {{medline-title
* {{medline-title
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|title=Expression of [[CDCA3]] Is a Prognostic Biomarker and Potential Therapeutic Target in Non-Small Cell Lung Cancer.
|date=06.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28487093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
|full-text-url=https://sci-hub.do/10.1016/j.jtho.2017.04.018
}}
}}
==IRF5==
==CDH2==


* {{medline-title
* {{medline-title
|title=Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice.
|title=CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type.
|date=11.2017
|date=30.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28905935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102368
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265269
}}
}}
==IRGM==
==CDO1==


* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway.
|date=09.2017
|date=19.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://sci-hub.do/10.1039/c8fo00740c
}}
}}
==ISG15==
==CDR2==


* {{medline-title
* {{medline-title
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|title=Neuro-degeneration profile of Alzheimer's patients: A brain morphometry study.
|date=14.01.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28459000
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397580
}}
}}
==ITGA2B==
==CEBPD==


* {{medline-title
* {{medline-title
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=04.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==ITGA3==
==CELSR2==


* {{medline-title
* {{medline-title
|title=A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells.
|title=Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.
|date=17.08.2020
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32807231
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329260
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013013
}}
}}
==ITGA5==
==CEP95==


* {{medline-title
* {{medline-title
|title=Kaempferol alleviates the reduction of developmental competence during aging of porcine oocytes.
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=11.2019
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31486245
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://sci-hub.do/10.1111/asj.13280
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
}}
==ITGA6==
==CER1==


* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=Radiographic screening of infants and young children with genetic predisposition for rare malignancies: DI[[CER1]] mutations and pleuropulmonary blastoma.
|date=05.2017
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25794098
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://sci-hub.do/10.2214/AJR.14.12802
}}
}}
==ITGAM==
==CFLAR==


* {{medline-title
* {{medline-title
|title=Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging.
|title=Senescence-secreted factors activate Myc and sensitize pretransformed cells to TRAIL-induced apoptosis.
|date=2019
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31732940
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589226
|full-text-url=https://sci-hub.do/10.1007/978-3-030-28524-1_11
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326894
}}
}}
==ITGB1==
==CH25H==


* {{medline-title
* {{medline-title
|title=Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.
|title=Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculature.
|date=05.2018
|date=21.03.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29599141
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24656052
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.117.310685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994432
}}
}}
==ITGB2==
==CHAD==


* {{medline-title
* {{medline-title
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|title=Insular cortex lesions, cardiac troponin, and detection of previously unknown atrial fibrillation in acute ischemic stroke: insights from the troponin elevation in acute ischemic stroke study.
|date=2019
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25835563
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
|full-text-url=https://sci-hub.do/10.1161/STROKEAHA.115.008681
}}
}}
==ITGB4==
==CHEK1==


* {{medline-title
* {{medline-title
|title=[[ITGB4]] deficiency induces senescence of airway epithelial cells through p53 activation.
|title=The Ubiquitin-like with PHD and Ring Finger Domains 1 ([[UHRF1]])/DNA Methyltransferase 1 ([[DNMT1]]) Axis Is a Primary Regulator of Cell Senescence.
|date=03.2019
|date=03.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30636108
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28100769
|full-text-url=https://sci-hub.do/10.1111/febs.14749
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339756
}}
}}
==ITK==
==CHEK2==


* {{medline-title
* {{medline-title
|title=Does Tetralogy of Fallot affect brain aging? A proof-of-concept study.
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=2018
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
==ITPR2==
==CHMP1B==


* {{medline-title
* {{medline-title
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling.
|title=Overexpression of [[CHMP7]] from rapeseed and Arabidopsis causes dwarfism and premature senescence in Arabidopsis.
|date=12.2018
|date=01.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27497741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923
|full-text-url=https://sci-hub.do/10.1016/j.jplph.2016.06.023
}}
}}
==JAGN1==
==CHMP2B==


* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.
|date=13.11.2018
|date=24.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225
}}
}}
==JAK3==
==CHMP7==


* {{medline-title
* {{medline-title
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|title=Overexpression of [[CHMP7]] from rapeseed and Arabidopsis causes dwarfism and premature senescence in Arabidopsis.
|date=04.2018
|date=01.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27497741
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
|full-text-url=https://sci-hub.do/10.1016/j.jplph.2016.06.023
}}
}}
==JAM3==
==CHRDL1==


* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=Identification of Human Juvenile Chondrocyte-Specific Factors that Stimulate Stem Cell Growth.
|date=05.2017
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26955889
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://sci-hub.do/10.1089/ten.TEA.2015.0366
}}
}}
==JARID2==
==CHRM4==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=02.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==JDP2==
==CHRNA7==


* {{medline-title
* {{medline-title
|title=Jun dimerization protein 2 controls hypoxia-induced replicative senescence via both the p16 -pRb and Arf-p53 pathways.
|title=Associations between genetic variations and global motion perception.
|date=11.2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29123987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31432227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666393
|full-text-url=https://sci-hub.do/10.1007/s00221-019-05627-7
}}
}}
==JUNB==
==CHRNE==


* {{medline-title
* {{medline-title
|title=Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of [[JUNB]].
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=19.02.2020
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31806366
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.11.145
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==KAT6B==
==CHSY1==


* {{medline-title
* {{medline-title
|title=Aging-associated decrease in the histone acetyltransferase [[KAT6B]] is linked to altered hematopoietic stem cell differentiation.
|title=Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in [i]skt[/i] Mice.
|date=02.2020
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32014431
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944401
}}
}}
==KCNAB3==
==CIC==


* {{medline-title
* {{medline-title
|title=Tracking age-correlated DNA methylation markers in the young.
|title=Cell-in-cell structures are more potent predictors of outcome than senescence or apoptosis in head and neck squamous cell carcinomas.
|date=09.2018
|date=18.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29933125
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28100275
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.06.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241920
}}
}}
==KCNB1==
==CIDEA==


* {{medline-title
* {{medline-title
|title=Oxidation of [[KCNB1]] potassium channels in the murine brain during aging is associated with cognitive impairment.
|title=Growth hormone receptor expression in human gluteal versus abdominal subcutaneous adipose tissue: Association with body shape.
|date=14.05.2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922570
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27015877
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471606
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084456
}}
}}
==KCNC3==
==CILP==


* {{medline-title
* {{medline-title
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird.
|title=Fibrotic-like changes in degenerate human intervertebral discs revealed by quantitative proteomic analysis.
|date=2017
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26463451
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723
|full-text-url=https://sci-hub.do/10.1016/j.joca.2015.09.020
}}
}}
==KCNE4==
==CILP2==


* {{medline-title
* {{medline-title
|title=Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice.
|title=Fibrotic-like changes in degenerate human intervertebral discs revealed by quantitative proteomic analysis.
|date=29.05.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29844497
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26463451
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974354
|full-text-url=https://sci-hub.do/10.1016/j.joca.2015.09.020
}}
}}
==KCNK2==
==CINP==


* {{medline-title
* {{medline-title
|title=Brain age prediction using deep learning uncovers associated sequence variants.
|title=Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging.
|date=27.11.2019
|date=01-03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31776335
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30681437
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881321
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000294
}}
}}
==KCNQ2==
==CIP2A==


* {{medline-title
* {{medline-title
|title=Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for [[GNG4]] and [[KCNQ2]] Genes.
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|date=05.2018
|date=08.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338302
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
}}
}}
==KCNQ4==
==CITED2==


* {{medline-title
* {{medline-title
|title=Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss.
|title=Downregulation of [[CITED2]] contributes to TGFβ-mediated senescence of tendon-derived stem cells.
|date=2020
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32327991
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28084522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160671
|full-text-url=https://sci-hub.do/10.1007/s00441-016-2552-1
}}
}}
==KCTD12==
==CIZ1==


* {{medline-title
* {{medline-title
|title=The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort.
|title=DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice.
|date=2020
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32970748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877805
}}
}}
==KDM2A==
==CLCN6==


* {{medline-title
* {{medline-title
|title=SIRT6 mono-ADP ribosylates [[KDM2A]] to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair.
|title=DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy.
|date=25.06.2020
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32584788
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26928272
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789590
}}
}}
==KDM2B==
==CLEC4E==


* {{medline-title
* {{medline-title
|title=Identification of Structural Elements of the Lysine Specific Demethylase 2B CxxC Domain Associated with Replicative Senescence Bypass in Primary Mouse Cells.
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|date=06.2020
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|full-text-url=https://sci-hub.do/10.1007/s10930-020-09895-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
}}
}}
==KDM3A==
==CLSTN2==


* {{medline-title
* {{medline-title
|title=[[KDM3A]] and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization.
|title=Investigating the influence of KIBRA and [[CLSTN2]] genetic polymorphisms on cross-sectional and longitudinal measures of memory performance and hippocampal volume in older individuals.
|date=22.11.2019
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704649
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26415670
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888768
|full-text-url=https://sci-hub.do/10.1016/j.neuropsychologia.2015.09.031
}}
}}
==KDM4A==
==CMA1==


* {{medline-title
* {{medline-title
|title=Structure-Based Discovery of a Selective [[KDM5A]] Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines.
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=15.01.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30650517
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
==KDM5A==
==CNGA3==


* {{medline-title
* {{medline-title
|title=Structure-Based Discovery of a Selective [[KDM5A]] Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines.
|title=DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers.
|date=15.01.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30650517
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28419903
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360022
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.04.006
}}
}}
==KDM6B==
==CNOT6==


* {{medline-title
* {{medline-title
|title=Histone demethylase [[KDM6B]] regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells.
|title=miR-29c-3p promotes senescence of human mesenchymal stem cells by targeting [[CNOT6]] through p53-p21 and p16-pRB pathways.
|date=08.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30825201
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26792405
|full-text-url=https://sci-hub.do/10.1002/jcp.28431
|full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2016.01.005
}}
}}
==KIF1A==
==CNTRL==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Antioxidant status, lipid and color stability of aged beef from grazing steers supplemented with corn grain and increasing levels of flaxseed.
|date=04.07.2019
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26318758
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1016/j.meatsci.2015.07.026
}}
}}
==KIF1B==
==COL12A1==


* {{medline-title
* {{medline-title
|title=[[BDNF]] trafficking and signaling impairment during early neurodegeneration is prevented by moderate physical activity.
|title=Genetic associations with age of menopause in familial longevity.
|date=12.2016
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30135925
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==KIFC3==
==COL13A1==


* {{medline-title
* {{medline-title
|title=Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging.
|title=[Alu insertion-deletion polymorphism of [[COL13A1]] and [[LAMA2]] genes: The analysis of association with longevity].
|date=08.2018
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29845728
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052466
 
}}
}}
==KLB==
==COL15A1==


* {{medline-title
* {{medline-title
|title=Infants Uniquely Express High Levels of [[RBM3]] and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain.
|title=Smooth muscle cell-specific deletion of [i]Col15a1[/i] unexpectedly leads to impaired development of advanced atherosclerotic lesions.
|date=2018
|date=01.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399610
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28283548
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451587
}}
}}
==KLF1==
==COL17A1==


* {{medline-title
* {{medline-title
|title=Mutant [[KLF1]] in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis.
|title=Hair follicle aging is driven by transepidermal elimination of stem cells via [[COL17A1]] proteolysis.
|date=24.08.2018
|date=05.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30143664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109071
|full-text-url=https://sci-hub.do/10.1126/science.aad4395
}}
}}
==KLF2==
==COL4A3==


* {{medline-title
* {{medline-title
|title=[[KLF2]] induces the senescence of pancreatic cancer cells by cooperating with FOXO4 to upregulate p21.
|title=Frequency of [[COL4A3]]/COL4A4 mutations amongst families segregating glomerular microscopic hematuria and evidence for activation of the unfolded protein response. Focal and segmental glomerulosclerosis is a frequent development during ageing.
|date=01.03.2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31866399
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25514610
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2019.111784
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267773
}}
}}
==KLF5==
==COL7A1==


* {{medline-title
* {{medline-title
|title=[[EGR1]] promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling.
|title=Biological Effects Induced by Specific Advanced Glycation End Products in the Reconstructed Skin Model of Aging.
|date=01.09.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201921
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26309782
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.06.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497626
}}
}}
==KLF6==
==COQ5==


* {{medline-title
* {{medline-title
|title=Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence.
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|date=2019
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31824948
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
}}
}}
==KLHL22==
==COQ6==


* {{medline-title
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|date=05.2018
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
}}
}}
==KPNA2==
==COQ9==


* {{medline-title
* {{medline-title
|title=Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-[[CRY1]] Transgenic Mice.
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|date=2019
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31179341
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
}}
}}
==KRT15==
==COX7A2==


* {{medline-title
* {{medline-title
|title=Extracellular proteoglycan decorin maintains human hair follicle stem cells.
|title=Proteomics Analysis to Identify and Characterize the Biomarkers and Physical Activities of Non-Frail and Frail Older Adults.
|date=12.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28367083
|full-text-url=https://sci-hub.do/10.1111/1346-8138.14678
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370285
}}
}}
==KRT18==
==CPA3==


* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=11.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
==KRT19==
==CPB2==


* {{medline-title
* {{medline-title
|title=Characterization of Krt19  allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc.
|title=Characterization of Clostridium perfringens in the feces of adult horses and foals with acute enterocolitis.
|date=01.2020
|date=01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187500
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24396174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878003
}}
}}
==KY==
==CPNE1==


* {{medline-title
* {{medline-title
|title=Combination of acupuncture and Chinese herbal formula for elderly adults with mild cognitive impairment: protocol for a randomized controlled trial.
|title=Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence.
|date=11.02.2019
|date=04.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30744676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274830
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371495
|full-text-url=https://sci-hub.do/10.1111/acel.13276
}}
}}
==LAG3==
==CPSF1==


* {{medline-title
* {{medline-title
|title=T Cell Transcriptional Profiling and Immunophenotyping Uncover [[LAG3]] as a Potential Significant Target of Immune Modulation in Multiple Myeloma.
|title=Genome-wide association study for lactation persistency, female fertility, longevity, and lifetime profit index traits in Holstein dairy cattle.
|date=01.2020
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31445183
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952061
|full-text-url=https://sci-hub.do/10.3168/jds.2016-11770
}}
}}
==LAGE3==
==CPT1A==


* {{medline-title
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|title=Alteration of fatty acid oxidation by increased [[CPT1A]] on replicative senescence of placenta-derived mesenchymal stem cells.
|date=11.04.2019
|date=03.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31900237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941254
}}
}}
==LAMA2==
==CRBN==


* {{medline-title
* {{medline-title
|title=[Alu insertion-deletion polymorphism of [[COL13A1]] and [[LAMA2]] genes: The analysis of association with longevity].
|title=Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity.
|date=10.2016
|date=24.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369589
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32332723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181703
}}
==CREB1==


* {{medline-title
|title=Arginine Methyltransferase [[PRMT8]] Provides Cellular Stress Tolerance in Aging Motoneurons.
|date=29.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113905
}}
}}
==LAMA5==
==CREBL2==


* {{medline-title
* {{medline-title
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
|title=Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence.
|date=05.06.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26029164
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432801
}}
}}
==LAT==
==CREG1==


* {{medline-title
* {{medline-title
|title=Is the combined auriculotherapy approach superior to magneto-auriculotherapy alone in aging males with lower urinary tract symptoms? A randomized controlled trial.
|title=[[CREG1]] ameliorates myocardial fibrosis associated with autophagy activation and Rab7 expression.
|date=16.01.2019
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30651007
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25774384
|full-text-url=https://sci-hub.do/10.1080/13685538.2018.1542673
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2014.05.027
}}
}}
==LCN2==
==CRHR1==


* {{medline-title
* {{medline-title
|title=Anthropometric and glucometabolic changes in an aged mouse model of lipocalin-2 overexpression.
|title=Koolen-de Vries Syndrome: Clinical Report of an Adult and Literature Review.
|date=01.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082752
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27852077
|full-text-url=https://sci-hub.do/10.1038/s41366-018-0171-5
|full-text-url=https://sci-hub.do/10.1159/000452724
}}
}}
==LDB2==
==CRISPLD2==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=11.2017
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
==LDLR==
==CRK==


* {{medline-title
* {{medline-title
|title=Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice.
|title=Crack-cocaine dependence and aging: effects on working memory.
|date=08.2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29903737
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27111700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115470
}}
}}
==LEF1==
==CRTC1==


* {{medline-title
* {{medline-title
|title=LncRNA H19 targets miR-22 to modulate H  O  -induced deregulation in nucleus pulposus cell senescence, proliferation, and ECM synthesis through Wnt signaling.
|title=[[TRPV1]] pain receptors regulate longevity and metabolism by neuropeptide signaling.
|date=06.2018
|date=22.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520849
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24855942
|full-text-url=https://sci-hub.do/10.1002/jcb.26738
|full-text-url=https://sci-hub.do/10.1016/j.cell.2014.03.051
}}
}}
==LGALS3==
==CRTC3==


* {{medline-title
* {{medline-title
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|title=A nutrigenomics approach for the study of anti-aging interventions: olive oil phenols and the modulation of gene and microRNA expression profiles in mouse brain.
|date=2018
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26695409
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
|full-text-url=https://sci-hub.do/10.1007/s00394-015-1134-4
}}
}}
==LGI1==
==CRYAA==


* {{medline-title
* {{medline-title
|title=Antibody-associated CNS syndromes without signs of inflammation in the elderly.
|title=Polymorphism rs7278468 is associated with Age-related cataract through decreasing transcriptional activity of the [[CRYAA]] promoter.
|date=03.10.2017
|date=17.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28878050
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26984531
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631166
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794711
}}
}}
==LGR6==
==CRYL1==


* {{medline-title
* {{medline-title
|title=Effect of defensins-containing eye cream on periocular rhytids and skin quality.
|title=Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old.
|date=08.2020
|date=28.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32614135
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28206976
|full-text-url=https://sci-hub.do/10.1111/jocd.13424
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400530
}}
}}
==LHCGR==
==CSAD==


* {{medline-title
* {{medline-title
|title=Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats.
|title=The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway.
|date=11.10.2020
|date=19.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050653
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590010
|full-text-url=https://sci-hub.do/10.1039/c8fo00740c
}}
}}
==LIFR==
==CSF1==


* {{medline-title
* {{medline-title
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.
|title=Pleiotropic effects of extended blockade of [[CSF1]]R signaling in adult mice.
|date=15.03.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24652541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378363
}}
}}
==LIN28B==
==CSF3R==


* {{medline-title
* {{medline-title
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|date=2017
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
}}
}}
==LIPA==
==CSN2==


* {{medline-title
* {{medline-title
|title=Influence of Habitual Physical Behavior - Sleeping, Sedentarism, Physical Activity - On Bone Health in Community-Dwelling Older People.
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells.
|date=2019
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31037056
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853
}}
}}
==LMX1A==
==CSNK1D==


* {{medline-title
* {{medline-title
|title=Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain.
|title=DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing.
|date=13.11.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30318292
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28254385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234859
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392537
}}
}}
==LOXL1==
==CST3==


* {{medline-title
* {{medline-title
|title=A blackberry-dill extract combination synergistically increases skin elasticity.
|title=Improved lipids, diastolic pressure and kidney function are potential contributors to familial longevity: a study on 60 Chinese centenarian families.
|date=10.2020
|date=25.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32583541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26911903
|full-text-url=https://sci-hub.do/10.1111/ics.12644
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766395
}}
}}
==LPAR3==
==CSTF2T==


* {{medline-title
* {{medline-title
|title=Upregulated microRNA-15b alleviates ovarian cancer through inhitbition of the PI3K/Akt pathway by targeting [[LPAR3]].
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=12.2019
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140597
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://sci-hub.do/10.1002/jcp.28799
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
}}
==LRP1==
==CTNS==


* {{medline-title
* {{medline-title
|title=Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome.
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading.
|date=06.2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268785
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255962
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869
}}
}}
==LRP2==
==CTSA==


* {{medline-title
* {{medline-title
|title=Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis.
|title=A [[CTSA]]-based consultation service to advance research on special and underserved populations.
|date=27.11.2018
|date=16.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485812
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33244406
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.11.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681147
}}
}}
==LRP6==
==CTSC==


* {{medline-title
* {{medline-title
|title=Low-density lipoprotein receptor-related protein 6-mediated signaling pathways and associated cardiovascular diseases: diagnostic and therapeutic opportunities.
|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.
|date=04.2020
|date=24.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32076828
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063
|full-text-url=https://sci-hub.do/10.1007/s00439-020-02124-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225
}}
}}
==LRP8==
==CTSD==


* {{medline-title
* {{medline-title
|title=SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating [[LRP8]] and ApoE.
|title=Serum levels of cathepsin D, sirtuin1, and endothelial nitric oxide synthase are correlatively reduced in elderly healthy people.
|date=02.07.2019
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31269452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26462844
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.06.002
|full-text-url=https://sci-hub.do/10.1007/s40520-015-0472-7
}}
}}
==LRRC34==
==CTSK==


* {{medline-title
* {{medline-title
|title=The polygenic nature of telomere length and the anti-ageing properties of lithium.
|title=Transcriptome Analysis of B Cell Immune Functions in Periodontitis: Mucosal Tissue Responses to the Oral Microbiome in Aging.
|date=03.2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27486459
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372618
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947588
}}
}}
==LRRC8B==
==CTSS==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=25.07.2018
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==LRRK1==
==CUBN==


* {{medline-title
* {{medline-title
|title=Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.
|title=A roadmap for the genetic analysis of renal aging.
|date=15.11.2017
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29056298
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26219736
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693787
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568960
}}
}}
==LTF==
==CUL3==


* {{medline-title
* {{medline-title
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|date=03.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
}}
}}
==LY6D==
==CUL4B==


* {{medline-title
* {{medline-title
|title=[[LY6D]]-induced macropinocytosis as a survival mechanism of senescent cells.
|title=[[CUL4B]] impedes stress-induced cellular senescence by dampening a p53-reactive oxygen species positive feedback loop.
|date=09.11.2020
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168631
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25464270
|full-text-url=https://sci-hub.do/10.1074/jbc.RA120.013500
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2014.11.010
}}
}}
==LY86==
==CUX1==


* {{medline-title
* {{medline-title
|title=Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=09.2019
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31280115
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732230
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
==LYG1==
==CXCL14==


* {{medline-title
* {{medline-title
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|title=Identification of genes associated with endometrial cell aging.
|date=03.2019
|date=01.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33258951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
|full-text-url=https://sci-hub.do/10.1093/molehr/gaaa078
}}
}}
==LYST==
==CXCL17==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=[Age-related aspects of the involvement of heat shock proteins in the pathogenesis of osteoarthritis].
|date=16.08.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849876
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
 
}}
}}
==MAF==
==CXCR6==


* {{medline-title
* {{medline-title
|title=Biocatalytic Degradation Efficiency of Postconsumer Polyethylene Terephthalate Packaging Determined by Their Polymer Microstructures.
|title=[[CXCR6]] Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and [[CD4]]  T-Cell-Dependent Control of Senescence.
|date=17.07.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31380212
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662049
|full-text-url=https://sci-hub.do/10.1053/j.gastro.2019.01.247
}}
}}
==MAF1==
==CXXC5==


* {{medline-title
* {{medline-title
|title=Beyond regulation of pol III: Role of [[MAF1]] in growth, metabolism, aging and cancer.
|title=Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny.
|date=04.2018
|date=13.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407795
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26436701
|full-text-url=https://sci-hub.do/10.1016/j.bbagrm.2018.01.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741551
}}
}}
==MAFB==
==CYB5R3==


* {{medline-title
* {{medline-title
|title=Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy.
|title=Overexpression of [[CYB5R3]] and [[NQO1]], two NAD  -producing enzymes, mimics aspects of caloric restriction.
|date=01.04.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30605403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052403
}}
}}
==MAL==
==CYCS==


* {{medline-title
* {{medline-title
|title=Daylight photodynamic therapy versus cryosurgery for the treatment and prophylaxis of actinic keratoses of the face - protocol of a multicenter, prospective, randomized, controlled, two-armed study.
|title=The Impact of Age and Sex in DLBCL: Systems Biology Analyses Identify Distinct Molecular Changes and Signaling Networks.
|date=25.10.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29070025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26691437
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676434
}}
}}
==MAOA==
==CYP11B1==


* {{medline-title
* {{medline-title
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.
|title=Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼.
|date=05.10.2017
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105764
}}
}}
==MAP1A==
==CYP26A1==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|date=04.07.2019
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
}}
}}
==MAP1B==
==CYP26B1==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia.
|date=04.07.2019
|date=20.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32385093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244205
}}
}}
==MAP2K3==
==CYP2B6==


* {{medline-title
* {{medline-title
|title=Associations of [i][[MAP2K3]][/i] Gene Variants With Superior Memory in SuperAgers.
|title=Developmental Expression of [[CYP2B6]]: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation.
|date=2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896098
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26608082
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931886
}}
}}
==MAP3K5==
==CYP2U1==


* {{medline-title
* {{medline-title
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|title=Genetic variants associated with lung function: the long life family study.
|date=08.10.2018
|date=01.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25409777
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228089
}}
}}
==MAP4K3==
==CYP4X1==


* {{medline-title
* {{medline-title
|title=[[MAP4K3]]/GLK in autoimmune disease, cancer and aging.
|title=Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes.
|date=22.10.2019
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31640697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28153492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806545
|full-text-url=https://sci-hub.do/10.1016/j.dmpk.2016.10.409
}}
}}
==MAPK10==
==CYP8B1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Synergic hypocholesterolaemic effect of n-3 PUFA and oestrogen by modulation of hepatic cholesterol metabolism in female rats.
|date=15.11.2018
|date=14.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26388416
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1017/S0007114515003517
}}
}}
==MAPK11==
==DAPK2==


* {{medline-title
* {{medline-title
|title=lncRNA ENSMUST00000134285 Increases [[MAPK11]] Activity, Regulating Aging-Related Myocardial Apoptosis.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=09.07.2018
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415197
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://sci-hub.do/10.1093/gerona/gly020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==MAPK13==
==DAZL==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=[[DAZL]] Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.
|date=15.11.2018
|date=30.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380414
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878787
}}
}}
==MAPK8==
==DCAF17==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Deletion of [[DDB1]]- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice.
|date=02.2019
|date=15.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907856
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003934
}}
}}
==MARCKS==
==DCAF7==


* {{medline-title
* {{medline-title
|title=Ser46-Phosphorylated [[MARCKS]] Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology.
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=07-08.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225354
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140116
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
}}
==MARCKSL1==
==DCHS1==


* {{medline-title
* {{medline-title
|title=[[MARCKSL1]] Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors.
|title=The atypical cadherin Dachsous1 localizes to the base of the ciliary apparatus in airway epithelia.
|date=04.2018
|date=13.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580842
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27074579
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952351
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.04.036
}}
}}
==MARK1==
==DCLRE1C==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|date=04.07.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
}}
}}
==MAS1==
==DCTN1==


* {{medline-title
* {{medline-title
|title=AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation.
|title=Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis.
|date=17.04.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667931
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26954557
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940107
|full-text-url=https://sci-hub.do/10.1159/000443664
}}
}}
==MATN3==
==DCTN2==


* {{medline-title
* {{medline-title
|title=Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis.
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|date=19.01.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31963938
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013758
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
}}
}}
==MAVS==
==DCTN6==


* {{medline-title
* {{medline-title
|title=Spontaneous activation of a [[MAVS]]-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes.
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|date=10.2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822807
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600710
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
}}
}}
==MAX==
==DDI2==


* {{medline-title
* {{medline-title
|title=Validation of the MedUseQ: A Self-Administered Screener for Older Adults to Assess Medication Use Problems.
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
|date=10.2019
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656678
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168
|full-text-url=https://sci-hub.do/10.1177/0897190018766789
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498
}}
}}
==MBD2==
==DDIT3==


* {{medline-title
* {{medline-title
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=02.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
}}
==MC1R==
==DDR1==


* {{medline-title
* {{medline-title
|title=In vitro behavior and UV response of melanocytes derived from carriers of [[[[CDKN2A]]]] mutations and [[MC1R]] variants.
|title=Age-related modifications of type I collagen impair [[DDR1]]-induced apoptosis in non-invasive breast carcinoma cells.
|date=03.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117292
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733741
|full-text-url=https://sci-hub.do/10.1111/pcmr.12732
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363044
}}
}}
==MCAT==
==DEFB1==


* {{medline-title
* {{medline-title
|title=Small molecules as therapeutic drugs for Alzheimer's disease.
|title=Association of Polymorphisms in Innate Immunity Genes [[TLR9]] and [[DEFB1]] with Human Longevity.
|date=04.2019
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30877034
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26028230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510253
|full-text-url=https://sci-hub.do/10.1007/s10517-015-2894-9
}}
}}
==MCF2L==
==DEPDC5==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|date=25.07.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
}}
}}
==MCM3==
==DEPTOR==


* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=[[DEPTOR]] at the Nexus of Cancer, Metabolism, and Immunity.
|date=27.07.2019
|date=01.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897294
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335100
}}
}}
==MCM4==
==DGAT2==


* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=27.07.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
==MCM5==
==DHCR7==


* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=Environmental and genetic determinants of vitamin D status among older adults in London, UK.
|date=27.07.2019
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26776442
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2016.01.005
}}
}}
==MCM6==
==DHFR==


* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=Excessive folic acid intake and relation to adverse health outcome.
|date=27.07.2019
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27131640
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://sci-hub.do/10.1016/j.biochi.2016.04.010
}}
}}
==MCM8==
==DHRS2==


* {{medline-title
* {{medline-title
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|title=Acute [[HSF1]] depletion induces cellular senescence through the [[MDM2]]-p53-p21 pathway in human diploid fibroblasts.
|date=2017
|date=08.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632240
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
|full-text-url=https://sci-hub.do/10.1242/jcs.210724
}}
}}
==MCM9==
==DHX57==


* {{medline-title
* {{medline-title
|title=MCM8- and [[MCM9]] Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors.
|title=Genetic variants near [[MLST8]] and [[DHX57]] affect the epigenetic age of the cerebellum.
|date=10.09.2019
|date=02.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31509747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26830004
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.07.095
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740877
}}
}}
==MCUR1==
==DIP2A==


* {{medline-title
* {{medline-title
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|title=Blocking the [[FSTL1]]-[[DIP2A]] Axis Improves Anti-tumor Immunity.
|date=09.2019
|date=14.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30110636
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.07.043
}}
}}
==MDK==
==DKK3==


* {{medline-title
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|title=Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging.
|date=20.06.2019
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24911145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071391
}}
}}
==MDN1==
==DLAT==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=16.08.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==ME1==
==DLC1==


* {{medline-title
* {{medline-title
|title=NADP-MALIC ENZYME 1 Affects Germination after Seed Storage in Arabidopsis thaliana.
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells.
|date=01.02.2019
|date=15.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30388244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052
|full-text-url=https://sci-hub.do/10.1093/pcp/pcy213
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031
}}
}}
==MECOM==
==DLGAP2==


* {{medline-title
* {{medline-title
|title=Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.
|title=Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
|date=11.2018
|date=01.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32877673
|full-text-url=https://sci-hub.do/10.1111/jgh.14149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502175
}}
}}
==MED25==
==DLL1==


* {{medline-title
* {{medline-title
|title=The [i]HAC1[/i] histone acetyltransferase promotes leaf senescence and regulates the expression of [i]ERF022[/i].
|title=MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting [[DLL1]] and Regulating PI3K/AKT Pathway.
|date=08.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468026
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710649
|full-text-url=https://sci-hub.do/10.1159/000492090
}}
}}
==MEFV==
==DLL4==


* {{medline-title
* {{medline-title
|title=The grandfather's fever.
|title=Dynamic regulation of [[NOTCH1]] activation and Notch ligand expression in human thymus development.
|date=02.2020
|date=13.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31401792
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30042180
|full-text-url=https://sci-hub.do/10.1007/s10067-019-04741-9
|full-text-url=https://sci-hub.do/10.1242/dev.165597
}}
}}
==MEOX2==
==DLX2==


* {{medline-title
* {{medline-title
|title=Reduced expression of microRNA-130a promotes endothelial cell senescence and age-dependent impairment of neovascularization.
|title=A gain-of-function senescence bypass screen identifies the homeobox transcription factor [[DLX2]] as a regulator of [[ATM]]-p53 signaling.
|date=26.05.2020
|date=01.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32457253
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26833729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743059
}}
}}
==MERTK==
==DMPK==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans.
|date=15.11.2018
|date=19.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30878478
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1016/j.jmb.2019.03.003
}}
}}
==MEST==
==DMRT1==
 
* {{medline-title
|title=The Jak-STAT target Chinmo prevents sex transformation of adult stem cells in the Drosophila testis niche.
|date=24.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25453558
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254588
}}
==DNAJB9==
 
* {{medline-title
|title=[[DNAJB9]] Inhibits p53-Dependent Oncogene-Induced Senescence and Induces Cell Transformation.
|date=30.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32264658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191047
}}
==DNAJC2==


* {{medline-title
* {{medline-title
|title=Improving specific autobiographical memory in older adults: impacts on mood, social problem solving, and functional limitations.
|title=ZRF1 is a novel S6 kinase substrate that drives the senescence programme.
|date=09.2018
|date=15.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825508
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28242756
|full-text-url=https://sci-hub.do/10.1080/13825585.2017.1365815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350561
}}
}}
==MFN1==
==DNM1==


* {{medline-title
* {{medline-title
Строка 9279: Строка 9805:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
}}
}}
==MFSD2A==
==DNM2==


* {{medline-title
* {{medline-title
|title=Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease.
|title=Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy.
|date=20.12.2019
|date=19.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31861865
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451843
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981746
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243013
}}
}}
==MGRN1==
==DNMT3L==


* {{medline-title
* {{medline-title
|title=Chronic and age-dependent effects of the spongiform neurodegeneration-associated [[MGRN1]] E3 ubiquitin ligase on mitochondrial homeostasis.
|title=Transient [[DNMT3L]] Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast.
|date=06.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089807
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32195249
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064442
}}
}}
==MIB1==
==DPP6==


* {{medline-title
* {{medline-title
|title=Immunohistochemical detection of senescence markers in human sarcomas.
|title=A novel structure associated with aging is augmented in the [[DPP6]]-KO mouse brain.
|date=02.2020
|date=23.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31899047
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33225987
|full-text-url=https://sci-hub.do/10.1016/j.prp.2019.152800
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682109
}}
}}
==MICA==
==DPYSL2==


* {{medline-title
* {{medline-title
|title=Derivation and Validation of a Geriatric-Sensitive Perioperative Cardiac Risk Index.
|title=Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease.
|date=16.11.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146612
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31733664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939615
}}
}}
==MICB==
==DRAM2==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=10.2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==MICU1==
==DRD1==


* {{medline-title
* {{medline-title
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|title=Impact of dopamine-related genetic variants on physical activity in old age - a cohort study.
|date=09.2019
|date=24.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32448293
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245799
}}
}}
==MLH3==
==DSC1==


* {{medline-title
* {{medline-title
|title=Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes.
|title=HDLs and the pathogenesis of atherosclerosis.
|date=19.10.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942922
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29561322
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679441
|full-text-url=https://sci-hub.do/10.1097/HCO.0000000000000508
}}
}}
==MMP12==
==DSG1==


* {{medline-title
* {{medline-title
|title=Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for [[MMP12]] through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice.
|title=Genetic effects on information processing speed are moderated by age--converging results from three samples.
|date=01.10.2017
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24629169
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1601696
|full-text-url=https://sci-hub.do/10.1111/gbb.12132
}}
}}
==MMP14==
==DSG2==


* {{medline-title
* {{medline-title
|title=Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells.
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=12.2017
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
}}
==MMP7==
==DSPP==


* {{medline-title
* {{medline-title
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|title=Effects of [i]p[/i]-Cresol on Senescence, Survival, Inflammation, and Odontoblast Differentiation in Canine Dental Pulp Stem Cells.
|date=2018
|date=21.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32967298
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555360
}}
}}
==MORF4L1==
==DTL==


* {{medline-title
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|date=20.06.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
}}
}}
==MPHOSPH6==
==DTNBP1==


* {{medline-title
* {{medline-title
|title=Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length.
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=05.03.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
}}
==MPL==
==DTX1==


* {{medline-title
* {{medline-title
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender.
|title=Analysis of diarrhetic shellfish poisoning toxins and pectenotoxin-2 in the bottlenose dolphin (Tursiops truncatus) by liquid chromatography-tandem mass spectrometry.
|date=10.2017
|date=16.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26381568
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0
|full-text-url=https://sci-hub.do/10.1016/j.chroma.2015.08.066
}}
}}
==MPST==
==DTX2==


* {{medline-title
* {{medline-title
|title=Methionine restriction leads to hyperhomocysteinemia and alters hepatic H S production capacity in Fischer-344 rats.
|title=Analysis of diarrhetic shellfish poisoning toxins and pectenotoxin-2 in the bottlenose dolphin (Tursiops truncatus) by liquid chromatography-tandem mass spectrometry.
|date=12.2018
|date=16.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30367932
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26381568
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.10.004
|full-text-url=https://sci-hub.do/10.1016/j.chroma.2015.08.066
}}
}}
==MR1==
==DUOX1==


* {{medline-title
* {{medline-title
|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers.
|title=Lifespan extension by peroxidase and dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in [i]C. elegans[/i].
|date=05.2018
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676501
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826
|full-text-url=https://sci-hub.do/10.1242/jcs.202119
}}
}}
==MRO==
==DUOX2==


* {{medline-title
* {{medline-title
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats].
|title=Lifespan extension by peroxidase and dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in [i]C. elegans[/i].
|date=08.05.2017
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676501
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110
|full-text-url=https://sci-hub.do/10.1242/jcs.202119
}}
}}
==MRPS5==
==DUSP1==


* {{medline-title
* {{medline-title
|title=Mutant [[MRPS5]] affects mitoribosomal accuracy and confers stress-related behavioral alterations.
|title=miR-1468-3p Promotes Aging-Related Cardiac Fibrosis.
|date=11.2018
|date=05.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30237157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32348937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216279
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191129
}}
}}
==MRTFA==
==DUSP2==


* {{medline-title
* {{medline-title
|title=Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse.
|title=Aging Increases Hippocampal [[DUSP2]] by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism.
|date=01.02.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30422822
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31293510
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355303
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603139
}}
}}
==MS4A1==
==DUSP6==


* {{medline-title
* {{medline-title
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|title=Protection of [[CD4]]  T cells from hepatitis C virus infection-associated senescence via ΔNp63-miR-181a-Sirt1 pathway.
|date=19.01.2019
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27354409
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069086
}}
}}
==MS4A4E==
==DUSP8==


* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats.
|date=28.03.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31400088
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826124
}}
}}
==MS4A6A==
==DUT==


* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=Simultaneous liquefaction, saccharification, and fermentation of L-lactic acid using aging paddy rice with hull by an isolated thermotolerant Enterococcus faecalis [[DUT]]1805.
|date=28.03.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32388689
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://sci-hub.do/10.1007/s00449-020-02364-y
}}
}}
==MSH2==
==DVL1==


* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=DNA methylation patterns associated with oxidative stress in an ageing population.
|date=25.02.2019
|date=25.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27884142
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123374
}}
}}
==MSH3==
==DYNC2H1==


* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=Role for intraflagellar transport in building a functional transition zone.
|date=25.02.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429209
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280794
}}
}}
==MSH6==
==ECE1==


* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=Ferulic Acid Suppresses Amyloid [i]β[/i] Production in the Human Lens Epithelial Cell Stimulated with Hydrogen Peroxide.
|date=25.02.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28409157
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376927
}}
}}
==MSRA==
==ECRG4==


* {{medline-title
* {{medline-title
|title=Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis.
|title=[[ECRG4]]: a new potential target in precision medicine.
|date=02.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30456853
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351846
|full-text-url=https://sci-hub.do/10.1007/s11684-018-0637-9
}}
}}
==MST1==
==ECSIT==


* {{medline-title
* {{medline-title
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|title=Longevity-related molecular pathways are subject to midlife "switch" in humans.
|date=25.06.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168962
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612641
}}
==EDAR==


* {{medline-title
|title=Pharmacological stimulation of Edar signaling in the adult enhances sebaceous gland size and function.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25207818
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269545
}}
}}
==MTRR==
==EDEM1==


* {{medline-title
* {{medline-title
|title=One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=12.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208817
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.05.013
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
==MUC5AC==
==EDF1==


* {{medline-title
* {{medline-title
|title=InflammAging at Ocular Surface: Clinical and Biomolecular Analyses in Healthy Volunteers.
|title=Silencing of FOREVER YOUNG FLOWER Like Genes from Phalaenopsis Orchids Promotes Flower Senescence and Abscission.
|date=01.04.2019
|date=25.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31022299
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33237274
|full-text-url=https://sci-hub.do/10.1167/iovs.18-25822
|full-text-url=https://sci-hub.do/10.1093/pcp/pcaa145
}}
}}
==MUC7==
==EDN1==


* {{medline-title
* {{medline-title
|title=Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model.
|title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway.
|date=24.09.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31554163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835954
|full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0
}}
}}
==MUL1==
==EDNRB==


* {{medline-title
* {{medline-title
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models.
|title=Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease.
|date=28.05.2019
|date=03.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26863197
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846424
}}
}}
==MUS81==
==EED==


* {{medline-title
* {{medline-title
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|title=Economic evaluations of eHealth technologies: A systematic review.
|date=2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897921
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999277
}}
}}
==MX1==
==EEF1A1==


* {{medline-title
* {{medline-title
|title=Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection.
|title=Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells.
|date=10.11.2018
|date=01.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878083
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27036204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818421
}}
}}
==MYCN==
==EEF2==


* {{medline-title
* {{medline-title
|title=Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells.
|title=Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells.
|date=2020
|date=01.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27036204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947931
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818421
}}
}}
==MYCNOS==
==EFCAB5==


* {{medline-title
* {{medline-title
|title=Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis.
|title=Genetic architecture of epigenetic and neuronal ageing rates in human brain regions.
|date=26.01.2017
|date=18.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28516910
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831999
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454371
}}
}}
==MYH10==
==EFNB1==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Activation of EphA4 and EphB2 Reverse Signaling Restores the Age-Associated Reduction of Self-Renewal, Migration, and Actin Turnover in Human Tendon Stem/Progenitor Cells.
|date=10.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26779014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701947
}}
}}
==MYLPF==
==EFNB2==


* {{medline-title
* {{medline-title
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle.
|title=Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo.
|date=15.05.2019
|date=15.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26980243
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791873
}}
}}
==MYO1F==
==EGR2==


* {{medline-title
* {{medline-title
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|title=Age-related impairment of bones' adaptive response to loading in mice is associated with sex-related deficiencies in osteoblasts but no change in osteocytes.
|date=2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24644060
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258100
}}
}}
==MYOC==
==EID3==


* {{medline-title
* {{medline-title
|title=Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
|title=Upregulation of [[EID3]] sensitizes breast cancer cells to ionizing radiation-induced cellular senescence.
|date=28.12.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389787
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30114644
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311499
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.08.022
}}
}}
==MYOF==
==EIF2B2==


* {{medline-title
* {{medline-title
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=08.10.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==MYSM1==
==EIF2B3==


* {{medline-title
* {{medline-title
|title=[[MYSM1]] Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=11.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33240758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==MYT1==
==EIF2B4==


* {{medline-title
* {{medline-title
|title=ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the [[MYT1]]-Egln3-Sirt1 Axis.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=01.10.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33038325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://sci-hub.do/10.1016/j.ymthe.2020.09.037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==NACA==
==EIF4E==


* {{medline-title
* {{medline-title
|title=Age and Sex Are Strongly Correlated to the Rate and Type of Mountain Injuries Requiring Search and Rescue Missions.
|title=Transcriptomic evidence that insulin signalling pathway regulates the ageing of subterranean termite castes.
|date=12.2019
|date=18.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31699646
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424344
|full-text-url=https://sci-hub.do/10.1016/j.wem.2019.06.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235038
}}
}}
==NAIP==
==ELANE==


* {{medline-title
* {{medline-title
|title=Protective effect of xanthohumol against age-related brain damage.
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|date=11.2017
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
}}
}}
==NBN==
==ELK1==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Tocotrienol-rich fraction prevents cellular aging by modulating cell proliferation signaling pathways.
|date=15.11.2017
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25945449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://sci-hub.do/10.7417/CT.2015.1825
}}
}}
==NBR1==
==ELL==


* {{medline-title
* {{medline-title
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
|title=Exceptional Longevity and Polygenic Risk for Cardiovascular Health.
|date=03.2018
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30889929
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471529
}}
}}
==NCK2==
==ELN==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Curcumin enhances the production of major structural components of elastic fibers, elastin, and fibrillin-1, in normal human fibroblast cells.
|date=10.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25333322
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://sci-hub.do/10.1080/09168451.2014.972324
}}
}}
==NCOR2==
==ELOVL6==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|date=25.07.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
}}
}}
==NDN==
==EMILIN2==


* {{medline-title
* {{medline-title
|title=The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging.
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066563
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
==NDRG1==
==EML6==


* {{medline-title
* {{medline-title
|title=Cx43 phosphorylation-mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein [[NDRG1]].
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|date=02.08.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189653
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682735
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
}}
}}
==NDRG2==
==ENPEP==


* {{medline-title
* {{medline-title
|title=[[NDRG2]] Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain.
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=04.01.2020
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31947996
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982267
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
==NDUFAB1==
==EOMES==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Eomesodermin Expression in CD4  T Cells Restricts Peripheral Foxp3 Induction.
|date=02.2018
|date=15.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26453746
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1501159
}}
}}
==NDUFS1==
==EPG5==


* {{medline-title
* {{medline-title
|title=Mapping the protein phosphorylation sites in human mitochondrial complex I (NADH: Ubiquinone oxidoreductase): A bioinformatics study with implications for brain aging and neurodegeneration.
|title=Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom.
|date=01.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29499254
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486404
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2018.02.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882010
}}
}}
==NDUFS3==
==ERAP1==


* {{medline-title
* {{medline-title
|title=Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10).
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=06.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==NDUFS8==
==ERBB3==


* {{medline-title
* {{medline-title
|title=Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity.
|title=[The expression of differential and matrix remodelling factors in human buccal epithelium in aging].
|date=01.10.2020
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32773682
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640689
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494633
 
}}
}}
==NDUFV2==
==ERBB4==


* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Overexpression of [[ERBB4]] rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
|date=07.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://sci-hub.do/10.1096/fj.201801690R
}}
}}
==NEFM==
==ERCC5==


* {{medline-title
* {{medline-title
|title=Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age.
|title=Identification of a [[ERCC5]] c.2333T>C (L778P) Variant in Two Tunisian Siblings With Mild Xeroderma Pigmentosum Phenotype.
|date=06.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30927131
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30838033
|full-text-url=https://sci-hub.do/10.1007/s10735-019-09820-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383105
}}
}}
==NEIL1==
==ERCC6==


* {{medline-title
* {{medline-title
|title=[[NEIL1]] stimulates neurogenesis and suppresses neuroinflammation after stress.
|title=Two Cockayne Syndrome patients with a novel splice site mutation - clinical and metabolic analyses.
|date=09.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175982
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29944916
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526462
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.001
}}
}}
==NEIL3==
==ERCC8==


* {{medline-title
* {{medline-title
|title=Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin.
|title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.
|date=2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31167196
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397
|full-text-url=https://sci-hub.do/10.1159/000500091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141
}}
}}
==NEK2==
==EREG==


* {{medline-title
* {{medline-title
|title=Upregulation of [[FOXM1]] leads to diminished drug sensitivity in myeloma.
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells.
|date=21.11.2018
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249818
|full-text-url=https://sci-hub.do/10.1071/RD14472
}}
}}
==NEO1==
==ESCO1==


* {{medline-title
* {{medline-title
|title=Neogenin-1 distinguishes between myeloid-biased and balanced [i]Hoxb5[/i]  mouse long-term hematopoietic stem cells.
|title=Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence.
|date=10.12.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754028
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26029164
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432801
}}
}}
==NFATC1==
==ESPL1==


* {{medline-title
* {{medline-title
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
|title=Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants.
|date=02.10.2017
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32574725
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461696
}}
}}
==NFKB1==
==ESRG==


* {{medline-title
* {{medline-title
|title=[[NFKB1]] gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|date=03.2020
|date=10.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32002656
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|full-text-url=https://sci-hub.do/10.1007/s00277-020-03935-5
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
}}
}}
==NGFR==
==ETFA==


* {{medline-title
* {{medline-title
|title=Evidence for changing nerve growth factor signalling mechanisms during development, maturation and ageing in the rat molar pulp.
|title=Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone.
|date=02.2019
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30099752
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24760536
|full-text-url=https://sci-hub.do/10.1111/iej.12997
|full-text-url=https://sci-hub.do/10.1530/EJE-14-0006
}}
==ETV5==
 
* {{medline-title
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
}}
}}
==NKAP==
==ETV6==


* {{medline-title
* {{medline-title
|title=[[NKAP]] Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors.
|title=[[FOXO1]] and [[ETV6]] genes may represent novel regulators of splicing factor expression in cellular senescence.
|date=2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31632967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783958
|full-text-url=https://sci-hub.do/10.1096/fj.201801154R
}}
}}
==NKIRAS2==
==EVC==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=Decreased centrality of subcortical regions during the transition to adolescence: a functional connectivity study.
|date=11.2017
|date=01.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25290886
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://sci-hub.do/10.1016/j.neuroimage.2014.09.063
}}
}}
==NKX2-5==
==EVL==


* {{medline-title
* {{medline-title
|title=Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart.
|title=Health Years in Total: A New Health Objective Function for Cost-Effectiveness Analysis.
|date=07.01.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30663680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31952678
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207148
|full-text-url=https://sci-hub.do/10.1016/j.jval.2019.10.014
}}
}}
==NKX6-1==
==EXD2==


* {{medline-title
* {{medline-title
|title=The dynamic methylome of islets in health and disease.
|title=[[EXD2]] governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation.
|date=09.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500828
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29335528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768570
|full-text-url=https://sci-hub.do/10.1038/s41556-017-0016-9
}}
}}
==NLRC5==
==EXOC3L2==


* {{medline-title
* {{medline-title
|title=Methylation of the genes ROD1, [[NLRC5]], and HKR1 is associated with aging in Hainan centenarians.
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
|date=02.02.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29394898
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889
}}
}}
==NLRP1==
==EXOC7==


* {{medline-title
* {{medline-title
|title=NADPH oxidase 2-mediated [[NLRP1]] inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro.
|title=[[PTBP1]]-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.
|date=04.2019
|date=09.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677569
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990503
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2019.01.025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048363
}}
}}
==NLRP12==
==EYA4==


* {{medline-title
* {{medline-title
|title=Persistent DNA damage-induced [[NLRP12]] improves hematopoietic stem cell function.
|title=A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records.
|date=21.05.2020
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434992
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27764096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072625
}}
}}
==NLRP6==
==EYS==


* {{medline-title
* {{medline-title
|title=LRP6 targeting suppresses gastric tumorigenesis via P14 -Mdm2-P53-dependent cellular senescence.
|title=Ablation of [[EYS]] in zebrafish causes mislocalisation of outer segment proteins, F-actin disruption and cone-rod dystrophy.
|date=19.12.2017
|date=05.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29340077
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28378834
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380955
}}
==EZR==
 
* {{medline-title
|title=Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29245059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801041
}}
}}
==NLRX1==
==F10==


* {{medline-title
* {{medline-title
|title=NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells.
|title=Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-[[F10]] cells by inducing senescence.
|date=26.02.2018
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828065
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.06.008
}}
}}
==NMI==
==F11R==


* {{medline-title
* {{medline-title
|title=Age-Dependent Control of Shoulder Muscles During a Reach-and-Lift Task.
|title=[Adhesion molecule JAM-A, its function and mechanism of epigenetic regulation].
|date=10.12.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31825888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28509452
|full-text-url=https://sci-hub.do/10.1123/japa.2019-0055
 
}}
}}
==NMRK2==
==F12==


* {{medline-title
* {{medline-title
|title=Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training.
|title=Multigenerational effects of carbendazim in Daphnia magna: From a subcellular to a population level.
|date=2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283350
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30508263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156423
|full-text-url=https://sci-hub.do/10.1002/etc.4307
}}
}}
==NMS==
==F8==


* {{medline-title
* {{medline-title
|title=Uncontrolled Diabetes as an Associated Factor with Dynapenia in Adults Aged 50 Years or Older: Sex Differences.
|title=Correlations between the signal complexity of cerebral and cardiac electrical activity: a multiscale entropy analysis.
|date=22.05.2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665234
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24498375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912068
}}
}}
==NMUR1==
==FA2H==


* {{medline-title
* {{medline-title
|title=[Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules].
|title=C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production.
|date=2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31685733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30184537
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428043
}}
}}
==NOA1==
==FABP1==


* {{medline-title
* {{medline-title
|title=The dependence of leaf senescence on the balance between 1-aminocyclopropane-1-carboxylate acid synthase 1 (ACS1)-catalysed ACC generation and nitric oxide-associated 1 (NOS1)-dependent NO accumulation in Arabidopsis.
|title=Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken.
|date=07.2019
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30734982
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065718
|full-text-url=https://sci-hub.do/10.1111/plb.12970
|full-text-url=https://sci-hub.do/10.3382/ps/pez249
}}
}}
==NOBOX==
==FADS1==


* {{medline-title
* {{medline-title
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|title=Aging and [[FADS1]] polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U- C]linoleic acid.
|date=18.10.2017
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31492428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
|full-text-url=https://sci-hub.do/10.1016/j.plefa.2019.07.003
}}
}}
==NOL12==
==FADS2==


* {{medline-title
* {{medline-title
|title=[[NOL12]] Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
|title=Genetic determinants of P wave duration and PR segment.
|date=15.06.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24850809
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141024
}}
}}
==NOTCH4==
==FAM13A==


* {{medline-title
* {{medline-title
|title=Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH.
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease.
|date=11.2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595581
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171
}}
}}
==NPAS2==
==FANCC==


* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=Fanconi Anemia complementation group C protein in metabolic disorders.
|date=21.11.2018
|date=21.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29930218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046246
}}
}}
==NPBWR1==
==FAR2==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=[[FAR2]] is associated with kidney disease in mice and humans.
|date=12.2017
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29652635
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139637
}}
}}
==NPC2==
==FAT4==


* {{medline-title
* {{medline-title
|title=Attenuation of the Niemann-Pick type [[C2]] disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2.
|title=Neuron-specific knockdown of the Drosophila fat induces reduction of life span, deficient locomotive ability, shortening of motoneuron terminal branches and defects in axonal targeting.
|date=08.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29655638
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28488382
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2018.04.001
|full-text-url=https://sci-hub.do/10.1111/gtc.12500
}}
}}
==NPM1==
==FBXO28==


* {{medline-title
* {{medline-title
|title=Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats.
|title=[[MYC]] Modulation around the CDK2/p27/SKP2 Axis.
|date=29.11.2019
|date=30.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31784606
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28665315
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541307
}}
}}
==NPRL2==
==FBXO32==


* {{medline-title
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|title=Endophilin-A Deficiency Induces the Foxo3a-Fbxo32 Network in the Brain and Causes Dysregulation of Autophagy and the Ubiquitin-Proteasome System.
|date=05.2018
|date=18.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27720640
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080600
}}
}}
==NPRL3==
==FBXO46==


* {{medline-title
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|date=05.2018
|date=19.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
}}
}}
==NPW==
==FBXO7==


* {{medline-title
* {{medline-title
|title=Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study.
|title=The [[FBXO7]] homologue nutcracker and binding partner PI31 in Drosophila melanogaster models of Parkinson's disease.
|date=09.2020
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32309980
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27936908
|full-text-url=https://sci-hub.do/10.1037/pag0000468
|full-text-url=https://sci-hub.do/10.1139/gen-2016-0087
}}
}}
==NR3C1==
==FBXW7==


* {{medline-title
* {{medline-title
|title=Glucocorticoid receptor ([[NR3C1]]) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians.
|title=[[MYC]] Modulation around the CDK2/p27/SKP2 Axis.
|date=02.2019
|date=30.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30553025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28665315
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.12.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541307
}}
}}
==NRARP==
==FCER1G==


* {{medline-title
* {{medline-title
|title=Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing [[NRARP]].
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|date=10.11.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30274778
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.09.045
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
}}
}}
==NRL==
==FCGR2A==


* {{medline-title
* {{medline-title
|title=Development of a cyclophosphamide stress test to predict resilience to aging in mice.
|title=Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells.
|date=12.2020
|date=03.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32613492
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377747
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00222-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710049
}}
}}
==NRM==
==FCGR3A==


* {{medline-title
* {{medline-title
|title=Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation.
|title=Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium.
|date=12.2019
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31445185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25963977
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192097
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450138
}}
}}
==NRXN3==
==FDPS==


* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
|date=07.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922
}}
}}
==NSF==
==FDXR==


* {{medline-title
* {{medline-title
|title=Effects of air pollution on children from a socioecological perspective.
|title=The aged testis. A good model to find proteins involved in age-related changes of testis by proteomic analysis.
|date=15.11.2019
|date=01-02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31727016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24597284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857293
 
}}
}}
==NT5E==
==FER==


* {{medline-title
* {{medline-title
|title=The [[NT5E]] gene variant strongly affects the degradation rate of inosine 5'-monophosphate under postmortem conditions in Japanese Black beef.
|title=Tracking the recognition of static and dynamic facial expressions of emotion across the life span.
|date=12.2019
|date=04.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31401370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30208425
|full-text-url=https://sci-hub.do/10.1016/j.meatsci.2019.107893
|full-text-url=https://sci-hub.do/10.1167/18.9.5
}}
}}
==NTHL1==
==FER1L6==


* {{medline-title
* {{medline-title
|title=Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=04.2020
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970600
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205949
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==NTN4==
==FEZ1==


* {{medline-title
* {{medline-title
|title=[[EGF]]/[[EGF]]R upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence.
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|date=04.12.2018
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514230
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
}}
}}
==NUCB2==
==FGB==


* {{medline-title
* {{medline-title
|title=Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise Killifish.
|title=[Clinical and genetic characteristics of long-livers in Moscow region].
|date=31.12.2019
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31906085
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019235
 
}}
}}
==NUPR1==
==FGF14==


* {{medline-title
* {{medline-title
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells.
|title=Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus.
|date=2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26687232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916041
}}
}}
==OCLN==
==FGFBP1==


* {{medline-title
* {{medline-title
|title=Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats.
|title=Muscle Fibers Secrete [[FGFBP1]] to Slow Degeneration of Neuromuscular Synapses during Aging and Progression of ALS.
|date=17.07.2019
|date=04.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242723
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28053031
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b02567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214636
}}
==FGG==
 
* {{medline-title
|title=Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24791650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163500
}}
}}
==OGA==
==FGL2==


* {{medline-title
* {{medline-title
|title=NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase.
|title=Developmental expression of B cell molecules in equine lymphoid tissues.
|date=19.11.2019
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31747588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28063478
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.10.053
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267323
}}
}}
==OLFML3==
==FIG4==


* {{medline-title
* {{medline-title
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|title=Knockdown of the Drosophila [[FIG4]] induces deficient locomotive behavior, shortening of motor neuron, axonal targeting aberration, reduction of life span and defects in eye development.
|date=02.2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26708557
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2015.12.011
}}
}}
==OMD==
==FIGNL1==


* {{medline-title
* {{medline-title
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|title=Comparative proteomic analysis of primordial follicles from ovaries of immature and aged rats.
|date=06.02.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391928
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
|full-text-url=https://sci-hub.do/10.3109/19396368.2015.1077903
}}
}}
==OOEP==
==FKRP==


* {{medline-title
* {{medline-title
|title=Maternal gene [i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes.
|title=Progressive Dystrophic Pathology in Diaphragm and Impairment of Cardiac Function in [[FKRP]] P448L Mutant Mice.
|date=18.11.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27711214
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053477
}}
}}
==OSGEP==
==FLNA==


* {{medline-title
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|title=[[SQSTM1]]/p62 mediates crosstalk between autophagy and the UPS in DNA repair.
|date=11.04.2019
|date=02.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391408
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391493
}}
}}
==OSM==
==FLT3==


* {{medline-title
* {{medline-title
|title=Age Differences in Sexual Minority Stress and the Importance of Friendship in Later Life.
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|date=04.11.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143546
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|full-text-url=https://sci-hub.do/10.1080/07317115.2020.1836107
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
}}
}}
==OTX2==
==FMN2==


* {{medline-title
* {{medline-title
|title=Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice.
|title=Genomic regulation of senescence and innate immunity signaling in the retinal pigment epithelium.
|date=01.03.2018
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29337233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25963977
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450138
}}
}}
==OXR1==
==FMO1==


* {{medline-title
* {{medline-title
|title=Oxidation resistance 1 is a novel senolytic target.
|title=Functional analysis and transcriptional output of the Göttingen minipig genome.
|date=08.2018
|date=14.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29766639
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26573612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052462
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647470
}}
}}
==P2RY10==
==FMO3==


* {{medline-title
* {{medline-title
|title=Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury.
|title=Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver.
|date=12.06.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189983
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28819071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697103
}}
}}
==P4HA2==
==FNTA==


* {{medline-title
* {{medline-title
|title=Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients.
|title=The Hip Morphology Changes with Ageing in Asian Population.
|date=03.09.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31560770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30363710
|full-text-url=https://sci-hub.do/10.1167/iovs.19-27921
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180959
}}
}}
==P4HA3==
==FOSL1==


* {{medline-title
* {{medline-title
|title=Age-associated genes in human mammary gland drive human breast cancer progression.
|title=RNA-Seq analysis reveals new evidence for inflammation-related changes in aged kidney.
|date=15.06.2020
|date=24.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32539762
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27153548
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294649
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058662
}}
}}
==PABPN1==
==FOSL2==


* {{medline-title
* {{medline-title
|title=Dysfunctional transcripts are formed by alternative polyadenylation in OPMD.
|title=LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.
|date=26.09.2017
|date=03.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088723
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32149459
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132339
}}
}}
==PAFAH2==
==FOXD1==


* {{medline-title
* {{medline-title
|title=Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs.
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|date=03.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30521374
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404557
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
}}
}}
==PARK7==
==FOXP2==


* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.
|date=06.2018
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247
}}
}}
==PAX1==
==FOXP4==


* {{medline-title
* {{medline-title
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.
|date=26.06.2018
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247
}}
}}
==PAX5==
==FRAS1==


* {{medline-title
* {{medline-title
|title=Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low [[PAX5]].
|title=[[FRAS1]]-related extracellular matrix 3 ([[FREM3]]) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk.
|date=08.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29425852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26441752
|full-text-url=https://sci-hub.do/10.1016/j.clim.2018.02.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584966
}}
}}
==PAX7==
==FREM3==


* {{medline-title
* {{medline-title
|title=Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits.
|title=[[FRAS1]]-related extracellular matrix 3 ([[FREM3]]) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk.
|date=10.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30006671
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26441752
|full-text-url=https://sci-hub.do/10.1007/s00421-018-3943-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584966
}}
}}
==PAX8==
==FRG1==


* {{medline-title
* {{medline-title
|title=Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging.
|title=Intergenerational response of steroidogenesis-related genes to maternal malnutrition.
|date=13.09.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31518338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781991
|full-text-url=https://sci-hub.do/10.1017/S2040174419000060
}}
}}
==PBX1==
==FRG2==


* {{medline-title
* {{medline-title
|title=Internalization of the TAT-[[PBX1]] fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence.
|title=Intergenerational response of steroidogenesis-related genes to maternal malnutrition.
|date=10.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436118
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789120
|full-text-url=https://sci-hub.do/10.1007/s10529-020-02909-x
|full-text-url=https://sci-hub.do/10.1017/S2040174419000060
}}
}}
==PCCA==
==FSTL1==


* {{medline-title
* {{medline-title
|title=Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism.
|title=Blocking the [[FSTL1]]-[[DIP2A]] Axis Improves Anti-tumor Immunity.
|date=03.2018
|date=14.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29159707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30110636
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832583
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.07.043
}}
}}
==PCCB==
==FSTL5==


* {{medline-title
* {{medline-title
|title=Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism.
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|date=03.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29159707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
}}
}}
==PCDHGA3==
==FZD1==


* {{medline-title
* {{medline-title
|title=DNA methylation associated with healthy aging of elderly twins.
|title=Frizzled-1 receptor regulates adult hippocampal neurogenesis.
|date=12.2018
|date=15.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30136078
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26980182
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791773
}}
}}
==PCMTD1==
==FZD4==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=MiR-1292 Targets [[FZD4]] to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway.
|date=12.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574422
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284756
}}
}}
==PDE10A==
==G0S2==


* {{medline-title
* {{medline-title
|title=Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain.
|title=Investigating the specific core genetic-and-epigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells.
|date=01.2018
|date=23.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175000
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26895224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890987
}}
}}
==PDE2A==
==G3BP1==


* {{medline-title
* {{medline-title
|title=TAK-915, a phosphodiesterase 2A inhibitor, ameliorates the cognitive impairment associated with aging in rodent models.
|title=Dissecting the molecular mechanisms that impair stress granule formation in aging cells.
|date=30.12.2019
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521738
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27965113
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2019.112192
|full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2016.12.008
}}
}}
==PDE4B==
==G6PC==


* {{medline-title
* {{medline-title
|title=Phosphodiesterase-4B as a Therapeutic Target for Cognitive Impairment and Obesity-Related Metabolic Diseases.
|title=Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of [[TP53]].
|date=2017
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28956331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941676
|full-text-url=https://sci-hub.do/10.1007/978-3-319-58811-7_5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106910
}}
}}
==PDE4C==
==G6PC2==


* {{medline-title
* {{medline-title
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|title=Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).
|date=04.2018
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24405752
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965585
}}
}}
==PDE5A==
==G6PC3==


* {{medline-title
* {{medline-title
|title=Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass.
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|date=23.06.2020
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32513693
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321982
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
}}
}}
==PDE9A==
==GAB2==


* {{medline-title
* {{medline-title
|title=Identification of new [[PDE9A]] isoforms and how their expression and subcellular compartmentalization in the brain change across the life span.
|title=Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936.
|date=05.2018
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29505961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29207374
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764388
}}
}}
==PDF==
==GABARAP==


* {{medline-title
* {{medline-title
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models.
|title=Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy.
|date=28.05.2019
|date=18.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32811819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434891
}}
}}
==PDGFRB==
==GADD45B==


* {{medline-title
* {{medline-title
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|title=Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging?
|date=04.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156709
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529819
}}
}}
==PDHB==
==GADD45G==


* {{medline-title
* {{medline-title
|title=Neuron-specific knockdown of Drosophila [[PDHB]] induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting.
|title=SIP1 is a downstream effector of [[GADD45G]] in senescence induction and growth inhibition of liver tumor cells.
|date=15.05.2018
|date=20.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501567
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26378039
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.02.035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741791
}}
}}
==PDK4==
==GADD45GIP1==


* {{medline-title
* {{medline-title
|title=Putrescine delays postovulatory aging of mouse oocytes by upregulating [[PDK4]] expression and improving mitochondrial activity.
|title=Nucleus accumbens-1/[[GADD45GIP1]] axis mediates cisplatin resistance through cellular senescence in ovarian cancer.
|date=16.12.2018
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554191
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28599472
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326651
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453174
}}
}}
==PEBP1==
==GAK==


* {{medline-title
* {{medline-title
|title=[i]Drosophila[/i] [[PEBP1]] inhibits intestinal stem cell aging via suppression of ERK pathway.
|title=Auxilin Underlies Progressive Locomotor Deficits and Dopaminergic Neuron Loss in a Drosophila Model of Parkinson's Disease.
|date=06.04.2018
|date=31.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719584
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28147270
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915051
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2017.01.005
}}
}}
==PER3==
==GALNT3==


* {{medline-title
* {{medline-title
|title=Effects of [[PER3]] clock gene polymorphisms on aging-related changes of the cerebral cortex.
|title=N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models.
|date=03.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28900721
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25860694
|full-text-url=https://sci-hub.do/10.1007/s00429-017-1513-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393098
}}
}}
==PES1==
==GART==


* {{medline-title
* {{medline-title
|title=Transcription factor RD26 is a key regulator of metabolic reprogramming during dark-induced senescence.
|title=Maintaining the continuity of HIV-care records for patients transferring care between centers: challenges, workloads, needs and risks.
|date=06.2018
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26829326
|full-text-url=https://sci-hub.do/10.1111/nph.15127
|full-text-url=https://sci-hub.do/10.1080/09540121.2016.1139042
}}
}}
==PEX19==
==GAS2==


* {{medline-title
* {{medline-title
|title=A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells.
|title=Truncated HBx-dependent silencing of [[GAS2]] promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53-mediated apoptosis.
|date=02.2020
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31854076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25925944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996960
|full-text-url=https://sci-hub.do/10.1002/path.4554
}}
}}
==PEX5==
==GAST==


* {{medline-title
* {{medline-title
|title=Aging lowers [[PEX5]] levels in cortical neurons in male and female mouse brains.
|title=The effects of age and muscle contraction on AMPK activity and heterotrimer composition.
|date=09.2020
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32777345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24747582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484460
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081450
}}
}}
==PF4V1==
==GATA1==


* {{medline-title
* {{medline-title
|title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells.
|title=Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass.
|date=05.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31299382
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708771
}}
}}
==PFKFB3==
==GBF1==


* {{medline-title
* {{medline-title
|title=DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system.
|title=Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor [[GBF1]].
|date=05.2018
|date=16.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27135347
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871568
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844403
}}
}}
==PGAP1==
==GCGR==


* {{medline-title
* {{medline-title
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|title=Population pharmacokinetics and pharmacodynamics of IONIS-[[GCGR]] , an antisense oligonucleotide for type 2 diabetes mellitus: a red blood cell lifespan model.
|date=07.2018
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28132162
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
|full-text-url=https://sci-hub.do/10.1007/s10928-017-9505-5
}}
}}
==PGK2==
==GCH1==


* {{medline-title
* {{medline-title
|title=Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
|title=Aging modifies the effect of [[GCH1]] RS11158026 on DAT uptake and Parkinson's disease clinical severity.
|date=01.2020
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31472347
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27871051
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2019.124650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209269
}}
}}
==PGLS==
==GCNA==


* {{medline-title
* {{medline-title
|title=547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates.
|title=Acceleration of age-associated methylation patterns in HIV-1-infected adults.
|date=28.11.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779658
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25807146
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883628
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373843
}}
==GCNT2==
 
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
}}
}}
==PGM1==
==GDA==


* {{medline-title
* {{medline-title
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle.
|title=Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces.
|date=15.05.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944897
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436911
}}
}}
==PHB==
==GDF5==


* {{medline-title
* {{medline-title
|title=Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
|title=An embryonic CaVβ1 isoform promotes muscle mass maintenance via [[GDF5]] signaling in adult mouse.
|date=02.2019
|date=06.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30674441
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31694926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412871
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aaw1131
}}
}}
==PHB2==
==GEN1==


* {{medline-title
* {{medline-title
|title=Prohibitin-2 is a novel regulator of p21  induced by depletion of γ-glutamylcyclotransferase.
|title=US acculturation and poor sleep among an intergenerational cohort of adult Latinos in Sacramento, California.
|date=29.01.2018
|date=01.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29307834
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30544165
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424080
}}
}}
==PHGDH==
==GFRA1==


* {{medline-title
* {{medline-title
|title=Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase.
|title=Determination phase at transition of gonocytes to spermatogonial stem cells improves establishment efficiency of spermatogonial stem cells in domestic cats.
|date=01.08.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31108107
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26411537
|full-text-url=https://sci-hub.do/10.1016/j.taap.2019.05.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685225
}}
}}
==PIGR==
==GFRAL==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Growth differentiation factor 15 ([[GDF15]]): A survival protein with therapeutic potential in metabolic diseases.
|date=02.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790643
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196666
}}
}}
==PIK3C2A==
==GGA3==


* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=The pathological roles of [[NDRG2]] in Alzheimer's disease, a study using animal models and APPwt-overexpressed cells.
|date=15.04.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28670853
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492714
}}
}}
==PIK3R1==
==GGCX==


* {{medline-title
* {{medline-title
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|title=Multiple Modes of Vitamin K Actions in Aging-Related Musculoskeletal Disorders.
|date=08.10.2018
|date=11.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31212662
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600274
}}
}}
==PIK3R2==
==GGT1==


* {{medline-title
* {{medline-title
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|title=Relation of size of seminal vesicles on ultrasound to premature ejaculation.
|date=06.2019
|date=09-10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27538475
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566849
}}
}}
==PIM1==
==GIGYF1==


* {{medline-title
* {{medline-title
|title=[[PIM1]]-catalyzed [[CBX8]] phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast.
|title=Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis.
|date=27.06.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29763603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26086452
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.05.070
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590642
}}
}}
==PIP5K1C==
==GIGYF2==


* {{medline-title
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|title=Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis.
|date=04.2016
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26086452
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590642
}}
}}
==PKD1==
==GJA3==


* {{medline-title
* {{medline-title
|title=The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response.
|title=Down-regulation of [[GJA3]] is associated with lens epithelial cell apoptosis and age-related cataract.
|date=16.03.2018
|date=26.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29420297
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28088522
|full-text-url=https://sci-hub.do/10.1242/jcs.207217
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.01.050
}}
}}
==PLA2G6==
==GJA8==


* {{medline-title
* {{medline-title
|title=Mutations in the Drosophila homolog of human [[PLA2G6]] give rise to age-dependent loss of psychomotor activity and neurodegeneration.
|title=The impact of [[GJA8]] SNPs on susceptibility to age-related cataract.
|date=13.02.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29440694
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30349978
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811537
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267713
}}
}}
==PLA2R1==
==GJB2==


* {{medline-title
* {{medline-title
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
|title=Reduced expression of Connexin26 and its DNA promoter hypermethylation in the inner ear of mimetic aging rats induced by d-galactose.
|date=12.2018
|date=26.09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25159847
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.08.063
}}
}}
==PLCG2==
==GJC2==


* {{medline-title
* {{medline-title
|title=A nonsynonymous mutation in [[PLCG2]] reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
|title=Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging.
|date=08.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31131421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32629311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.04.017
}}
}}
==PLD3==
==GLP1R==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=A nutrigenomics approach for the study of anti-aging interventions: olive oil phenols and the modulation of gene and microRNA expression profiles in mouse brain.
|date=16.08.2019
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26695409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://sci-hub.do/10.1007/s00394-015-1134-4
}}
}}
==PLK1==
==GLRA1==


* {{medline-title
* {{medline-title
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|title=Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model.
|date=09.2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26861500
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798846
}}
}}
==PLN==
==GLRA2==


* {{medline-title
* {{medline-title
|title=An analysis of the costs of treating aged patients in a large clinical hospital in Poland under the pressure of recent demographic trends.
|title=Gene Expression Switching of Receptor Subunits in Human Brain Development.
|date=2020
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26636753
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670163
}}
}}
==PLXNA4==
==GLRA3==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Gene Expression Switching of Receptor Subunits in Human Brain Development.
|date=15.11.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26636753
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670163
}}
}}
==PMP22==
==GMDS==


* {{medline-title
* {{medline-title
|title=Role of microRNAs in senescence and its contribution to peripheral neuropathy in the arsenic exposed population of West Bengal, India.
|title=Validity and clinical utilization of the Chinese version of the Gotland Male Depression Scale at a men's health polyclinic.
|date=02.2018
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29107899
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25246791
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2017.09.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166311
}}
}}
==PMS1==
==GML==


* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=Age independently affects myelin integrity as detected by magnetization transfer magnetic resonance imaging in multiple sclerosis.
|date=25.02.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24936415
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053639
}}
}}
==PMS2==
==GNA14==


* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle.
|date=25.02.2019
|date=29.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671246
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://sci-hub.do/10.4238/gmr16029091
}}
}}
==POLG2==
==GNAQ==


* {{medline-title
* {{medline-title
|title=An N-Ethyl-N-Nitrosourea (ENU)-Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice.
|title=[[GNAQ]]  expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system.
|date=03.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30395686
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31680437
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446808
|full-text-url=https://sci-hub.do/10.1111/pcmr.12843
}}
}}
==POLL==
==GNG11==


* {{medline-title
* {{medline-title
|title=Temporal trends in loss of life expectancy after a cancer diagnosis among the Australian population.
|title=[[GNG11]] (G-protein subunit γ 11) suppresses cell growth with induction of reactive oxygen species and abnormal nuclear morphology in human SUSM-1 cells.
|date=04.2020
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32062407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28380310
|full-text-url=https://sci-hub.do/10.1016/j.canep.2020.101686
|full-text-url=https://sci-hub.do/10.1139/bcb-2016-0248
}}
}}
==POLR3A==
==GNG4==


* {{medline-title
* {{medline-title
|title=Nucleolar disruption, activation of P53 and premature senescence in [[POLR3A]]-mutated Wiedemann-Rautenstrauch syndrome fibroblasts.
|title=Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for [[GNG4]] and [[KCNQ2]] Genes.
|date=12.2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32976914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338302
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098
}}
}}
==PON1==
==GNPAT==


* {{medline-title
* {{medline-title
|title=Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview.
|title=Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.
|date=02.05.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31052559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30128650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562914
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1307-2
}}
}}
==POU3F2==
==GNRH2==


* {{medline-title
* {{medline-title
|title=[[POU3F2]] participates in cognitive function and adult hippocampal neurogenesis via mammalian-characteristic amino acid repeats.
|title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus.
|date=02.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782255
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287
|full-text-url=https://sci-hub.do/10.1111/gbb.12408
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460
}}
}}
==POU5F1==
==GORAB==


* {{medline-title
* {{medline-title
|title=Cell quality evaluation with gene expression analysis of spheroids (3D) and adherent (2D) adipose stem cells.
|title=Examining tissue composition, whole-bone morphology and mechanical behavior of Gorab  mice tibiae: A mouse model of premature aging.
|date=24.10.2020
|date=08.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33148459
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29108851
|full-text-url=https://sci-hub.do/10.1016/j.gene.2020.145269
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695220
}}
}}
==PPA2==
==GOT1==


* {{medline-title
* {{medline-title
|title=Characterization of long living yeast deletion mutants that lack mitochondrial metabolism genes DSS1, [[PPA2]] and AFG3.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=20.07.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31082499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://sci-hub.do/10.1016/j.gene.2019.05.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==PPARG==
==GP1BA==


* {{medline-title
* {{medline-title
|title=The [[PPARG]] Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=04-06.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29116943
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938164
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==PPARGC1A==
==GP2==


* {{medline-title
* {{medline-title
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|title=Estimation of human age using N-glycan profiles from bloodstains.
|date=08.07.2019
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25787342
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550657
}}
}}
==PPFIA1==
==GPBAR1==


* {{medline-title
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|title=Activation of the bile acid receptor [[GPBAR1]] (TGR5) ameliorates interleukin-1β (IL-1β)- induced chondrocytes senescence.
|date=01.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119246
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.06.154
}}
}}
==PPM1A==
==GPC1==


* {{medline-title
* {{medline-title
|title=The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1.
|title=Decreased expression of [[GPC1]] in human skin keratinocytes and epidermis during ageing.
|date=03.08.2019
|date=15.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31382626
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31430521
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723262
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110693
}}
}}
==PPP1R3C==
==GPD1==


* {{medline-title
* {{medline-title
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|title=The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing.
|date=03.2019
|date=01.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26049045
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509511
}}
}}
==PPP2R1A==
==GPD2==


* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Switching off [[IMMP2L]] signaling drives senescence via simultaneous metabolic alteration and blockage of cell death.
|date=15.04.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808012
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993829
}}
}}
==PPP2R3C==
==GPR1==


* {{medline-title
* {{medline-title
|title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver.
|title=The Arabidopsis [[GPR1]] Gene Negatively Affects Pollen Germination, Pollen Tube Growth, and Gametophyte Senescence.
|date=04.2019
|date=21.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486124
}}
}}
==PPP3CB==
==GPR101==


* {{medline-title
* {{medline-title
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|title=Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent.
|date=2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663685
}}
}}
==PRDM1==
==GPR158==


* {{medline-title
* {{medline-title
|title=Age-related changes in the [[BACH2]] and [[PRDM1]] genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.
|title=RbAp48 Protein Is a Critical Component of [[GPR158]]/OCN Signaling and Ameliorates Age-Related Memory Loss.
|date=17.01.2019
|date=23.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654767
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355501
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725275
}}
}}
==PRDM16==
==GPR173==


* {{medline-title
* {{medline-title
|title=Assessment of the Aging of the Brown Adipose Tissue by F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna .
|title=Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent.
|date=2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079616
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663685
}}
}}
==PRDM8==
==GPR19==


* {{medline-title
* {{medline-title
|title=[[PRDM8]] reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=20.08.2020
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32819411
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439574
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==PRDX6==
==GPR37==


* {{medline-title
* {{medline-title
|title=Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task.
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|date=2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31417400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684764
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
}}
}}
==PREP==
==GPR37L1==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|date=12.2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
}}
}}
==PRG4==
==GPR6==


* {{medline-title
* {{medline-title
|title=Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis.
|title=Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy.
|date=08.02.2018
|date=22.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415892
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32959881
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821202
|full-text-url=https://sci-hub.do/10.1093/infdis/jiaa599
}}
}}
==PRKAA1==
==GPRC5C==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Anti-diabetic action of all-trans retinoic acid and the orphan G protein coupled receptor [[GPRC5C]] in pancreatic β-cells.
|date=02.2019
|date=31.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28228611
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://sci-hub.do/10.1507/endocrj.EJ16-0338
}}
}}
==PRKCB==
==GPX3==


* {{medline-title
* {{medline-title
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|title=Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract.
|date=18.03.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857780
}}
}}
==PRKCH==
==GPX7==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7.
|date=15.11.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659168
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052468
}}
}}
==PRKDC==
==GRAP==


* {{medline-title
* {{medline-title
|title=DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis.
|title=ASSOCIATION OF PREVASCUL[[AR]] [[VIT]]REOUS FISSURES AND CISTERNS WI[[TH]] [[VIT]]REOUS DEGENERATION AS ASSESSED BY SWEPT SOURCE OPTICAL COHE[[REN]]CE TO[[MOG]]RAPHY.
|date=29.08.2019
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31464599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25874366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716822
|full-text-url=https://sci-hub.do/10.1097/IAE.0000000000000540
}}
}}
==PRKG1==
==GREM1==


* {{medline-title
* {{medline-title
|title=Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis.
|title=[[GREM1]] inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells.
|date=15.07.2018
|date=09.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660387
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151168
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.04.007
|full-text-url=https://sci-hub.do/10.1080/03008207.2020.1736054
}}
}}
==PRKN==
==GREM2==


* {{medline-title
* {{medline-title
|title=[[PRKN]]-regulated mitophagy and cellular senescence during COPD pathogenesis.
|title=Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis.
|date=03.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30290714
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31709279
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831850
}}
}}
==PRLR==
==GRIA1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models.
|date=15.11.2018
|date=30.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27265785
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135662
}}
}}
==PRM1==
==GRID1==


* {{medline-title
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|title=Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies.
|date=01.02.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109663
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2020.02.005
}}
}}
==PRM2==
==GRIN2A==


* {{medline-title
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|title=Gene Expression Switching of Receptor Subunits in Human Brain Development.
|date=01.02.2019
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26636753
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670163
}}
}}
==PRMT1==
==GRINA==


* {{medline-title
* {{medline-title
|title=Reactive oxygen species extend insect life span using components of the insulin-signaling pathway.
|title=Genome-wide association study for lactation persistency, female fertility, longevity, and lifetime profit index traits in Holstein dairy cattle.
|date=12.09.2017
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847950
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604040
|full-text-url=https://sci-hub.do/10.3168/jds.2016-11770
}}
}}
==PRMT8==
==GRK4==


* {{medline-title
* {{medline-title
|title=Arginine Methyltransferase [[PRMT8]] Provides Cellular Stress Tolerance in Aging Motoneurons.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=29.08.2018
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==PRNP==
==GRK6==


* {{medline-title
* {{medline-title
|title=Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS.
|title=Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity.
|date=06.2020
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32516343
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304635
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801044
}}
}}
==PRR9==
==GRM2==


* {{medline-title
* {{medline-title
|title=Circadian control of [i]ORE1[/i] by [[PRR9]] positively regulates leaf senescence in [i]Arabidopsis[/i].
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=14.08.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30065116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099856
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==PRRX1==
==GRM6==


* {{medline-title
* {{medline-title
|title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis.
|title=Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics.
|date=12.2018
|date=08.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27267879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897877
}}
}}
==PSAP==
==GRP==


* {{medline-title
* {{medline-title
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|title=The loss of glucose-regulated protein 78 ([[GRP]]78) during normal aging or from siRNA knockdown augments human alpha-synuclein (α-syn) toxicity to rat nigral neurons.
|date=08.2018
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25863526
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433578
}}
}}
==PSMB8==
==GRPR==


* {{medline-title
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|title=Gastrin-Releasing Peptide Receptor Knockdown Induces Senescence in Glioblastoma Cells.
|date=04.2016
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26780458
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
|full-text-url=https://sci-hub.do/10.1007/s12035-016-9696-6
}}
}}
==PSMD11==
==GSN==


* {{medline-title
* {{medline-title
|title=The effect and mechanism of 19S proteasome [[PSMD11]]/Rpn6 subunit in D-Galactose induced mimetic aging models.
|title=Oral administration of alcalase potato protein hydrolysate-APPH attenuates high fat diet-induced cardiac complications via TGF-β/[[GSN]] axis in aging rats.
|date=01.09.2020
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32450067
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30240538
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.112093
|full-text-url=https://sci-hub.do/10.1002/tox.22651
}}
}}
==PSMD13==
==GSR==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Meeting the Need for Training in Geriatrics: The Geriatrics Education for Specialty Residents Program.
|date=2019
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28513843
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://sci-hub.do/10.1111/jgs.14966
}}
}}
==PSMD14==
==GSTA3==


* {{medline-title
* {{medline-title
|title=Upregulation of deubiquitinase [[PSMD14]] in lung adenocarcinoma (LUAD) and its prognostic significance.
|title=Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.
|date=2020
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32226511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25001375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150915
}}
}}
==PSMG1==
==GSTK1==


* {{medline-title
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=03.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==PTCH1==
==GSTM2==


* {{medline-title
* {{medline-title
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|title=Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage.
|date=02.2019
|date=07.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32574561
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342013
}}
}}
==PTGS2==
==GSTO1==


* {{medline-title
* {{medline-title
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=21.05.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==PTK2B==
==GSTT2==


* {{medline-title
* {{medline-title
|title=Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=11.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297968
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==PTK7==
==GTSF1==


* {{medline-title
* {{medline-title
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|title=Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes.
|date=05.07.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26577303
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853592
}}
}}
==PTN==
==GUK1==


* {{medline-title
* {{medline-title
|title=Connecting Metainflammation and Neuroinflammation Through the [[PTN]]-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development.
|title=Characterization of the impact of GMP/GDP synthesis inhibition on replicative lifespan extension in yeast.
|date=2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31031625
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32232569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474308
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367712
}}
}}
==PTP4A3==
==GYS2==


* {{medline-title
* {{medline-title
|title=Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease.
|title=In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers.
|date=05.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32402127
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986936
|full-text-url=https://sci-hub.do/10.1002/adbi.202000044
|full-text-url=https://sci-hub.do/10.1111/jpn.12831
}}
}}
==PTPN1==
==GZMH==


* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=Age-related profiling of DNA methylation in CD8  T cells reveals changes in immune response and transcriptional regulator genes.
|date=06.2018
|date=19.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26286994
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541364
}}
}}
==PTPRC==
==GZMK==


* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=Comprehensive Profiling of an Aging Immune System Reveals Clonal [[GZMK]]  CD8  T Cells as Conserved Hallmark of Inflammaging.
|date=05.2017
|date=21.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33271118
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2020.11.005
}}
}}
==PTPRD==
==HABP4==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Microneedle fractional radiofrequency increases epidermal hyaluronan and reverses age-related epidermal dysfunction.
|date=15.11.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26415023
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1002/lsm.22420
}}
}}
==PTPRR==
==HACE1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=[[HACE1]] reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.
|date=15.11.2018
|date=25.02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24516159
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939919
}}
}}
==PTTG1==
==HADH==


* {{medline-title
* {{medline-title
|title=[Down-regulated [[PTTG1]] expression promotes the senescence of human prostate cancer LNCaP-AI].
|title=Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone.
|date=03.2019
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32216239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24760536
 
|full-text-url=https://sci-hub.do/10.1530/EJE-14-0006
}}
}}
==PUM1==
==HADHA==


* {{medline-title
* {{medline-title
|title=Identification of reference genes for RT-qPCR data normalisation in aging studies.
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.
|date=27.09.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764958
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223
}}
}}
==PYCR1==
==HAP1==


* {{medline-title
* {{medline-title
|title=A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals [[POSTN]] As a New Element in Proline Metabolic Disorder.
|title=The longevity SNP rs2802292 uncovered: [[HSF1]] activates stress-dependent expression of [[FOXO3]] through an intronic enhancer.
|date=12.2018
|date=20.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009585
}}
}}
==QRFPR==
==HAS3==


* {{medline-title
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|title=Microneedle fractional radiofrequency increases epidermal hyaluronan and reverses age-related epidermal dysfunction.
|date=01.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26415023
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
|full-text-url=https://sci-hub.do/10.1002/lsm.22420
}}
}}
==RAB1B==
==HAX1==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|date=2019
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
}}
}}
==RACK1==
==HBM==


* {{medline-title
* {{medline-title
|title=Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging.
|title=The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis.
|date=05.11.2019
|date=25.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31636180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31553309
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781972
}}
}}
==RAD23A==
==HBZ==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and [[HBZ]].
|date=2019
|date=16.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27322308
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926181
}}
}}
==RAD50==
==HCRT==


* {{medline-title
* {{medline-title
|title=Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells.
|title=Age-related central regulation of orexin and [[NPY]] in the short-lived African killifish Nothobranchius furzeri.
|date=01.09.2018
|date=15.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775409
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172637
|full-text-url=https://sci-hub.do/10.1002/cne.24638
}}
}}
==RAD51B==
==HDAC10==


* {{medline-title
* {{medline-title
|title=Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human [[RAD52]] gene in a cardiovascular cohort.
|title=Middle-aged female rats lack changes in histone H3 acetylation in the anterior hypothalamus observed in young females on the day of a luteinizing hormone surge.
|date=10.2017
|date=17.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024686
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31434815
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.10.003
|full-text-url=https://sci-hub.do/10.5582/bst.2019.01162
}}
}}
==RAD51C==
==HDAC11==


* {{medline-title
* {{medline-title
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|date=06.2019
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
}}
}}
==RAD9A==
==HDAC8==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.
|date=02.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771
}}
}}
==RAF1==
==HDAC9==


* {{medline-title
* {{medline-title
|title=Circular [i]ANRIL[/i] isoforms switch from repressors to activators of [i]p15/CDKN2B[/i] expression during [[RAF1]] oncogene-induced senescence.
|title=MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation.
|date=29.09.2020
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32862732
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25751060
|full-text-url=https://sci-hub.do/10.1080/15476286.2020.1812910
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396470
}}
}}
==RAG2==
==HDC==


* {{medline-title
* {{medline-title
|title=Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation.
|title=Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells.
|date=2020
|date=07.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387685
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.02.092
}}
}}
==RAI1==
==HDX==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence.
|date=25.07.2018
|date=28.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28105936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249001
}}
}}
==RARB==
==HELLS==


* {{medline-title
* {{medline-title
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
|title=The Ubiquitin-like with PHD and Ring Finger Domains 1 ([[UHRF1]])/DNA Methyltransferase 1 ([[DNMT1]]) Axis Is a Primary Regulator of Cell Senescence.
|date=12.2019
|date=03.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28100769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339756
}}
}}
==RB1==
==HEPN1==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Functional analysis and transcriptional output of the Göttingen minipig genome.
|date=15.11.2017
|date=14.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26573612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647470
}}
}}
==RBM25==
==HERC2==


* {{medline-title
* {{medline-title
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif.
|title=Endothelial [[SIRT1]] prevents adverse arterial remodeling by facilitating [[HERC2]]-mediated degradation of acetylated LKB1.
|date=29.04.2019
|date=28.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27259994
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129914
}}
}}
==RBM3==
==HGSNAT==


* {{medline-title
* {{medline-title
|title=Infants Uniquely Express High Levels of [[RBM3]] and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain.
|title=Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC.
|date=2018
|date=01.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399610
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27491071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047683
}}
}}
==RBM38==
==HHIP==


* {{medline-title
* {{medline-title
|title=Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating [[PTEN]].
|title=Hhip haploinsufficiency sensitizes mice to age-related emphysema.
|date=15.03.2018
|date=09.08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29330147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27444019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340497
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987811
}}
}}
==RBMXL1==
==HHLA2==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma.
|date=16.08.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30768970
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://sci-hub.do/10.1016/j.jtho.2019.01.024
}}
}}
==RBP1==
==HIF3A==


* {{medline-title
* {{medline-title
|title=The SR proteins SF2 and [[RBP1]] regulate triglyceride storage in the fat body of Drosophila.
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|date=27.08.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277943
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.151
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
}}
}}
==RBP4==
==HIP1==


* {{medline-title
* {{medline-title
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats].
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=08.05.2017
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
==RCAN1==
==HIPK2==


* {{medline-title
* {{medline-title
|title=Mitochondrial dysfunction and endoplasmic reticulum stress involved in oocyte aging: an analysis using single-cell RNA-sequencing of mouse oocytes.
|title=Nore1a drives Ras to flick the P53 senescence switch.
|date=08.06.2019
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31176373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27314075
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909421
}}
}}
==REC8==
==HJV==


* {{medline-title
* {{medline-title
|title=Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice.
|title=Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting.
|date=10.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884219
|full-text-url=https://sci-hub.do/10.1007/s11655-018-2835-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596404
}}
}}
==RELA==
==HK1==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).
|date=12.2017
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24405752
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965585
}}
}}
==RELB==
==HLA-DMA==


* {{medline-title
* {{medline-title
|title=New control of the senescence barrier in breast cancer.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158912
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051141
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==REV1==
==HLA-DPA1==


* {{medline-title
* {{medline-title
|title=[[REV1]] inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks.
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|date=17.11.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168727
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682577
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
}}
}}
==RGS14==
==HLA-DRA==


* {{medline-title
* {{medline-title
|title=Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14.
|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.
|date=08.2018
|date=24.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29654651
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225
}}
}}
==RGS2==
==HLA-DRB4==


* {{medline-title
* {{medline-title
|title=Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone.
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=01.05.2019
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31043680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494869
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
}}
==RHCG==
==HLA-DRB5==


* {{medline-title
* {{medline-title
|title=Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.
|title=Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study.
|date=06.06.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170090
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28269768
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594797
|full-text-url=https://sci-hub.do/10.3233/JAD-160774
}}
}}
==RHEBL1==
==HLA-E==


* {{medline-title
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|title=Senescent cells evade immune clearance via [[HLA-E]]-mediated NK and CD8  T cell inhibition.
|date=03.2018
|date=03.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160572
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547655
}}
}}
==RHOB==
==HLA-F==


* {{medline-title
* {{medline-title
|title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes.
|title=Extended lifespan and reduced adiposity in mice lacking the FAT10 gene.
|date=13.06.2019
|date=08.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24706839
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986194
}}
}}
==RICTOR==
==HLF==


* {{medline-title
* {{medline-title
|title=Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase.
|title=Healthy lifestyle and normal waist circumference are associated with a lower 5-year risk of type 2 diabetes in middle-aged and elderly individuals: Results from the healthy aging longitudinal study in Taiwan (HALST).
|date=11.2019
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31476350
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28178143
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059097
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313000
}}
}}
==RIF1==
==HMGA1==


* {{medline-title
* {{medline-title
|title=53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
|title=Characterization of [i][[HMGA1]]P6[/i] transgenic mouse embryonic fibroblasts.
|date=02.01.2020
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653568
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32787507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513866
}}
}}
==RIMS2==
==HMGCS2==


* {{medline-title
* {{medline-title
|title=Age-related gene and miRNA expression changes in airways of healthy individuals.
|title=The aged testis. A good model to find proteins involved in age-related changes of testis by proteomic analysis.
|date=06.03.2019
|date=01-02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24597284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403379
 
}}
}}
==RIPK2==
==HMMR==


* {{medline-title
* {{medline-title
|title=RIP kinases as modulators of inflammation and immunity.
|title=The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations.
|date=09.2018
|date=15.12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25172923
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253829
}}
}}
==RNF10==
==HMX1==


* {{medline-title
* {{medline-title
|title=Reduced RING finger protein 10 expression in macrophages is associated with aging-related inflammation.
|title=Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence.
|date=28.11.2020
|date=28.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33249776
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28105936
|full-text-url=https://sci-hub.do/10.1002/2211-5463.13049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249001
}}
}}
==RNF13==
==HNF4A==


* {{medline-title
* {{medline-title
|title=The effects of environmental stressors on candidate aging associated genes.
|title=Hepatocyte Nuclear Factor-4α P2 Promoter Variants Are Associated With the Risk of Metabolic Syndrome and Testosterone Deficiency in Aging Taiwanese Men.
|date=08.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32344118
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415809
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110952
|full-text-url=https://sci-hub.do/10.1016/j.jsxm.2018.09.012
}}
}}
==RNF144A==
==HNRNPA0==


* {{medline-title
* {{medline-title
|title=Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease.
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|date=09.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31280115
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
}}
}}
==RNF168==
==HNRNPA2B1==


* {{medline-title
* {{medline-title
|title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair.
|title=Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans.
|date=06.2019
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27363602
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013025
}}
}}
==RORA==
==HNRNPF==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=15.11.2018
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
}}
==ROS1==
==HNRNPM==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|date=15.11.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
}}
}}
==RPA2==
==HOXA3==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=11.2017
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==RPE65==
==HOXA4==


* {{medline-title
* {{medline-title
|title=Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells.
|title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes.
|date=08.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30091312
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085187
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529
}}
}}
==RPIA==
==HOXA5==


* {{medline-title
* {{medline-title
|title=Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming.
|title=[[HOXA5]] localization in postnatal and adult mouse brain is suggestive of regulatory roles in postmitotic neurons.
|date=20.08.2019
|date=01.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31433975
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27650319
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716532
|full-text-url=https://sci-hub.do/10.1002/cne.24123
}}
}}
==RPL11==
==HOXB7==


* {{medline-title
* {{medline-title
|title=[[NOL12]] Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
|title=Impact of [[HOXB7]] overexpression on human adipose-derived mesenchymal progenitors.
|date=15.06.2019
|date=19.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423808
}}
}}
==RPL13==
==HOXC13==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence.
|date=2019
|date=28.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28105936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249001
}}
}}
==RPL30==
==HOXD8==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts.
|date=2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849838
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431633
}}
}}
==RPL31==
==HP1BP3==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging.
|date=2019
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27460150
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018442
}}
}}
==RPL36==
==HPDL==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Characterization and cytological effects of a novel glycated gelatine substrate.
|date=2019
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24486986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://sci-hub.do/10.1088/1748-6041/9/2/025001
}}
}}
==RPL37==
==HPR==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=Sod1 gene ablation in adult mice leads to physiological changes at the neuromuscular junction similar to changes that occur in old wild-type mice.
|date=2019
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25841780
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762177
}}
}}
==RPL4==
==HPSE==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin.
|date=2019
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32159248
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://sci-hub.do/10.1002/cbin.11339
}}
}}
==RPS19BP1==
==HRC==


* {{medline-title
* {{medline-title
|title=Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence.
|title=Differences in false recollection according to the cognitive reserve of healthy older people.
|date=10.2020
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659678
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26982550
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2020.153275
|full-text-url=https://sci-hub.do/10.1080/13825585.2016.1146221
}}
}}
==RPS6KB1==
==HRH4==


* {{medline-title
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|title=Histamime Receptor H4 as a New Therapeutic Target for Age-related Macular Degeneration.
|date=2018
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30074739
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
==RPTOR==


* {{medline-title
|title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016
}}
}}
==RRAD==
==HRK==


* {{medline-title
* {{medline-title
|title=Pan-senescence transcriptome analysis identified [[RRAD]] as a marker and negative regulator of cellular senescence.
|title=Gene expression of key regulators of mitochondrial biogenesis is sex dependent in mice with growth hormone receptor deletion in liver.
|date=01.2019
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391675
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25855408
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.10.457
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394730
}}
}}
==RRM1==
==HS2ST1==


* {{medline-title
* {{medline-title
|title=α-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1.
|title=Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity.
|date=08.2019
|date=31.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31940721
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612645
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999708
}}
}}
==RRM2B==
==HSD17B1==


* {{medline-title
* {{medline-title
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.
|title=Genetic Basis of the Relationship Between Reproduction and Longevity: A Study on Common Variants of Three Genes in Steroid Hormone Metabolism--CYP17, [[HSD17B1]], and [[COMT]].
|date=15.07.2018
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25936248
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179
|full-text-url=https://sci-hub.do/10.1089/rej.2015.1665
}}
}}
==RSF1==
==HSD17B14==


* {{medline-title
* {{medline-title
|title=The SR proteins SF2 and [[RBP1]] regulate triglyceride storage in the fat body of Drosophila.
|title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts.
|date=27.08.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277943
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.151
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3
}}
}}
==RTN4==
==HSD17B4==


* {{medline-title
* {{medline-title
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|title=Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein-2 deficiency.
|date=07.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29341299
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
|full-text-url=https://sci-hub.do/10.1111/bpa.12586
}}
}}
==RUNX3==
==HSF4==


* {{medline-title
* {{medline-title
|title=circLARP4 induces cellular senescence through regulating miR-761/[[RUNX3]]/p53/p21 signaling in hepatocellular carcinoma.
|title=Effect of [[HSF4]]b on age related cataract may through its novel downstream target Hif1α.
|date=02.2019
|date=24.10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30520539
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25088997
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361555
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.07.118
}}
}}
==RXFP3==
==HSPA13==


* {{medline-title
* {{medline-title
|title=The [[RXFP3]] receptor is functionally associated with cellular responses to oxidative stress and DNA damage.
|title=Genetic associations with age of menopause in familial longevity.
|date=03.12.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794429
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932917
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==RXRA==
==HSPA1L==


* {{medline-title
* {{medline-title
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling.
|title=Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the [[HSPA1L]]-mitophagy pathway.
|date=12.2018
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31965731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059143
}}
}}
==RXRG==
==HSPA5==


* {{medline-title
* {{medline-title
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=2017
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
==S100A12==
==HSPBP1==


* {{medline-title
* {{medline-title
|title=Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model.
|title=[[BAG2]] Interferes with CHIP-Mediated Ubiquitination of HSP72.
|date=06.07.2018
|date=30.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991479
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28042827
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297704
}}
}}
==S100A13==
==HSPG2==


* {{medline-title
* {{medline-title
|title=[[S100A13]] promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=23.01.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30670674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366962
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==S100A6==
==HTR1A==


* {{medline-title
* {{medline-title
|title=Sex differences in distribution of cannabinoid receptors (CB1 and CB2), [[S100A6]] and CacyBP/SIP in human ageing hearts.
|title=Gene Expression Switching of Receptor Subunits in Human Brain Development.
|date=27.11.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30482253
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26636753
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258148
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670163
}}
==HTR2A==
 
* {{medline-title
|title=Region-specific regulation of the serotonin 2A receptor expression in development and ageing in post mortem human brain.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25041420
|full-text-url=https://sci-hub.do/10.1111/nan.12167
}}
}}
==S1PR3==
==HTR2B==


* {{medline-title
* {{medline-title
|title=Sexual dimorphism of metabolic and vascular dysfunction in aged mice and those lacking the sphingosine 1-phosphate receptor 3.
|title=Up-regulation of serotonin receptor 2B mRNA and protein in the peri-infarcted area of aged rats and stroke patients.
|date=01.12.2017
|date=05.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28943478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27013593
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951222
}}
}}
==SAA2==
==HTR4==


* {{medline-title
* {{medline-title
|title=Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells.
|title=[[ADAM19]] and [[HTR4]] variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136502
}}
}}
==SALL1==
==HTR5A==


* {{medline-title
* {{medline-title
|title=[[SALL1]] functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex.
|title=Gene Expression Switching of Receptor Subunits in Human Brain Development.
|date=06.04.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29625565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26636753
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889587
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670163
}}
}}
==SAMD10==
==HYOU1==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=11.2017
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
==SAMD12==
==IBSP==


* {{medline-title
* {{medline-title
|title=Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom.
|title=P4 medicine and osteoporosis: a systematic review.
|date=05.2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27873024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882010
|full-text-url=https://sci-hub.do/10.1007/s00508-016-1125-3
}}
}}
==SARM1==
==ICAM5==


* {{medline-title
* {{medline-title
|title=Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.
|title=A reverse genetics cell-based evaluation of genes linked to healthy human tissue age.
|date=03.10.2017
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27698205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640801
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161526
}}
}}
==SAT1==
==ICE1==


* {{medline-title
* {{medline-title
|title=Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action.
|title=ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1.
|date=08.2020
|date=19.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544364
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469548
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031079
}}
}}
==SATB2==
==ID2==


* {{medline-title
* {{medline-title
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=06.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==SCAMP4==
==IDO1==


* {{medline-title
* {{medline-title
|title=[[SCAMP4]] enhances the senescent cell secretome.
|title=Advanced age negatively impacts survival in an experimental brain tumor model.
|date=01.07.2018
|date=06.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967290
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27493076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006183
}}
}}
==SCGN==
==IFI27==


* {{medline-title
* {{medline-title
|title=Detection and evaluation of DNA methylation markers found at [[SCGN]] and [[KLF14]] loci to estimate human age.
|title=Ultraviolet B irradiation-induced keratinocyte senescence and impaired development of 3D epidermal reconstruct.
|date=11.2017
|date=01.06.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854399
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33151171
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011
|full-text-url=https://sci-hub.do/10.2478/acph-2021-0011
}}
}}
==SCN2A==
==IFIH1==


* {{medline-title
* {{medline-title
|title=Na 1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age.
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|date=09.09.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31501495
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733925
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
}}
}}
==SCN2B==
==IFITM1==


* {{medline-title
* {{medline-title
|title=MicroRNA‑449a regulates the progression of brain aging by targeting [[SCN2B]] in SAMP8 mice.
|title=Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection.
|date=04.2020
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32124967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230210
}}
}}
==SCN5A==
==IFITM3==


* {{medline-title
* {{medline-title
|title=[Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug].
|title=Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein [[IFITM3]].
|date=2018
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30175758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242426
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00114
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613042
}}
}}
==SCN9A==
==IFNAR2==


* {{medline-title
* {{medline-title
|title=The [[SCN9A]] channel and plasma membrane depolarization promote cellular senescence through Rb pathway.
|title=Type I interferon receptors in goose: molecular cloning, structural identification, evolutionary analysis and age-related tissue expression profile.
|date=06.2018
|date=25.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29446526
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25617523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946064
|full-text-url=https://sci-hub.do/10.1016/j.gene.2015.01.040
}}
}}
==SCNN1B==
==IFNB1==


* {{medline-title
* {{medline-title
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects.
|title=Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa.
|date=18.10.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26197995
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712099
}}
}}
==SCO1==
==IFNGR2==


* {{medline-title
* {{medline-title
|title=Real-Time PCR Analysis of Metabolism-Related Genes in a Long-Lived Model of C. elegans.
|title=Lifespan of mice and primates correlates with immunoproteasome expression.
|date=2020
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32219749
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25866968
|full-text-url=https://sci-hub.do/10.1007/978-1-0716-0471-7_12
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463211
}}
}}
==SCX==
==IFT122==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Co-chaperone p23 regulates C. elegans Lifespan in Response to Temperature.
|date=15.11.2018
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25830239
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382338
}}
}}
==SDC2==
==IFT140==


* {{medline-title
* {{medline-title
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|title=The Role of [[IFT140]] in Osteogenesis of Adult Mice Long Bone.
|date=01.10.2017
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31034313
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669857
}}
}}
==SDC3==
==IGF2BP2==


* {{medline-title
* {{medline-title
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|title=Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons.
|date=01.10.2017
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26487704
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757025
}}
}}
==SDC4==
==IGF2BP3==


* {{medline-title
* {{medline-title
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|title=Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth.
|date=01.10.2017
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888162
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b00833
}}
}}
==SDHB==
==IGFBP6==


* {{medline-title
* {{medline-title
|title=Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=12.02.2020
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32059608
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074517
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==SELENBP1==
==IGHD==


* {{medline-title
* {{medline-title
|title=A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.
|title=Growth Hormone Deficiency: Health and Longevity.
|date=01.2020
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31557719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416709
}}
}}
==SELENOH==
==IGHG2==


* {{medline-title
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|title=Human IgG2- and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age.
|date=03.2019
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28546550
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636940
}}
}}
==SELENOK==
==IGHM==


* {{medline-title
* {{medline-title
|title=Dietary selenium deficiency and supplementation differentially modulate the expression of two ER-resident selenoproteins (selenoprotein K and selenoprotein M) in the ovaries of aged mice: Preliminary data.
|title=Developmental expression of B cell molecules in equine lymphoid tissues.
|date=09.2020
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736983
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28063478
|full-text-url=https://sci-hub.do/10.1016/j.repbio.2020.07.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267323
}}
}}
==SELENOP==
==IGLL5==


* {{medline-title
* {{medline-title
|title=Analyses of Selenotranscriptomes and Selenium Concentrations in Response to Dietary Selenium Deficiency and Age Reveal Common and Distinct Patterns by Tissue and Sex in Telomere-Dysfunctional Mice.
|title=Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution.
|date=10.2017
|date=07.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28855418
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26638776
|full-text-url=https://sci-hub.do/10.3945/jn.117.247775
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686820
}}
}}
==SELENOT==
==IGSF1==


* {{medline-title
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|title=Age-related gene and miRNA expression changes in airways of healthy individuals.
|date=03.2019
|date=06.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842487
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403379
}}
}}
==SELENOV==
==IKBKB==


* {{medline-title
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=03.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
==SELENOW==
==IL10RA==


* {{medline-title
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|title=Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease.
|date=03.2019
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26193622
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853027
}}
}}
==SEMA3A==
==IL11==


* {{medline-title
* {{medline-title
|title=Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging.
|title=Myocardial Infarction Superimposed on Aging: MMP-9 Deletion Promotes M2 Macrophage Polarization.
|date=05.03.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661929
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25878031
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2018.12.021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175450
}}
}}
==SEMA6C==
==IL13RA1==


* {{medline-title
* {{medline-title
|title=Suppression of [[SEMA6C]] promotes preantral follicles atresia with decreased cell junctions in mice ovaries.
|title=Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle.
|date=04.2019
|date=29.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30256425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671246
|full-text-url=https://sci-hub.do/10.1002/jcp.27294
|full-text-url=https://sci-hub.do/10.4238/gmr16029091
}}
}}
==SENP1==
==IL17C==


* {{medline-title
* {{medline-title
|title=Aging-related SUMOylation pattern in the cortex and blood plasma of wild type mice.
|title=Age-dependent changes in inflammation and extracellular matrix in bovine oviduct epithelial cells during the post-ovulatory phase.
|date=06.03.2018
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325714
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27580129
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.01.004
|full-text-url=https://sci-hub.do/10.1002/mrd.22693
}}
}}
==SENP6==
==IL17D==


* {{medline-title
* {{medline-title
|title=Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses.
|title=Genetic determinants of P wave duration and PR segment.
|date=10.2020
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32827359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24850809
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576240
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141024
}}
}}
==SERPINA1==
==IL17RA==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon.
|date=02.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039977
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://sci-hub.do/10.1080/07420528.2017.1361436
}}
}}
==SERPINB2==
==IL17RC==


* {{medline-title
* {{medline-title
|title=An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through [[SERPINB2]].
|title=Overstimulation can create health problems due to increases in PI3K/Akt/GSK3 insensitivity and GSK3 activity.
|date=03.07.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25089247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117863
}}
}}
==SESN1==
==IL18==


* {{medline-title
* {{medline-title
|title=Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis.
|title=Aging and the Inflammasomes.
|date=09.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751091
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30536177
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.006
|full-text-url=https://sci-hub.do/10.1007/978-3-319-89390-7_13
}}
}}
==SESN3==
==IL18RAP==


* {{medline-title
* {{medline-title
|title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging.
|title=Age and pro-inflammatory gene polymorphisms influence adjacent segment disc degeneration more than fusion does in patients treated for chronic low back pain.
|date=25.09.2018
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26281980
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052
|full-text-url=https://sci-hub.do/10.1007/s00586-015-4181-x
}}
}}
==SF1==
==IL1RN==


* {{medline-title
* {{medline-title
|title=Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice.
|title=Transcriptomic and epigenetic analyses reveal a gender difference in aging-associated inflammation: the Vitality 90  study.
|date=15.04.2019
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576894
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26188803
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.12.034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506741
}}
}}
==SFPQ==
==IL21==


* {{medline-title
* {{medline-title
|title=Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis.
|title=The expression of [[IL6]] and 21 in crossbred calves upregulated by inactivated trivalent FMD vaccine.
|date=08.04.2020
|date=03.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32267831
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24555796
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185106
|full-text-url=https://sci-hub.do/10.1080/10495398.2013.834826
}}
}}
==SFRP1==
==IL22==


* {{medline-title
* {{medline-title
|title=[Role and alterations of DNA methylation during the aging and cancer].
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|date=01.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
}}
}}
==SFRP2==
==IL2RA==


* {{medline-title
* {{medline-title
|title=[Role and alterations of DNA methylation during the aging and cancer].
|title=Dynamic demethylation of the [[IL2RA]] promoter during in vitro CD4  T cell activation in association with [[IL2RA]] expression.
|date=01.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30096258
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140818
}}
}}
==SFRP5==
==IL2RG==


* {{medline-title
* {{medline-title
|title=[[SFRP5]] serves a beneficial role in arterial aging by inhibiting the proliferation, migration and inflammation of smooth muscle cells.
|title=Generation of a Nonhuman Primate Model of Severe Combined Immunodeficiency Using Highly Efficient Genome Editing.
|date=11.2018
|date=07.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30221661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27374787
|full-text-url=https://sci-hub.do/10.3892/mmr.2018.9467
|full-text-url=https://sci-hub.do/10.1016/j.stem.2016.06.003
}}
}}
==SGK1==
==IL33==


* {{medline-title
* {{medline-title
|title=Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells.
|title=Interleukin33 deficiency causes tau abnormality and neurodegeneration with Alzheimer-like symptoms in aged mice.
|date=05.2020
|date=04.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223380
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28675392
|full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.120.14642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538122
}}
}}
==SGSH==
==IL36RN==


* {{medline-title
* {{medline-title
|title=MPS-IIIA mice acquire autistic behaviours with age.
|title=Elderly-Onset Generalized Pustular Psoriasis without a Previous History of Psoriasis Vulgaris.
|date=07.2018
|date=05-08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520737
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26351429
|full-text-url=https://sci-hub.do/10.1007/s10545-018-0160-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560317
}}
}}
==SH2B3==
==IL6ST==


* {{medline-title
* {{medline-title
|title=Genome-wide meta-analysis associates HLA-DQA1/DRB1 and [[LPA]] and lifestyle factors with human longevity.
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|date=13.10.2017
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29030599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715013
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
}}
}}
==SHANK3==
==IL9==


* {{medline-title
* {{medline-title
|title=Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background.
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|date=10.10.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30305163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180595
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
}}
}}
==SHD==
==IMMP2L==


* {{medline-title
* {{medline-title
|title=Does self-reported hearing difficulty decrease older adults' cognitive and physical functioning? The mediating role of social isolation.
|title=Switching off [[IMMP2L]] signaling drives senescence via simultaneous metabolic alteration and blockage of cell death.
|date=11.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33036703
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808012
|full-text-url=https://sci-hub.do/10.1016/j.maturitas.2020.06.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993829
}}
}}
==SIK3==
==IMPA1==


* {{medline-title
* {{medline-title
|title=Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids.
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=25.09.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566214
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518561
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
}}
==SIL1==
==IMPA2==


* {{medline-title
* {{medline-title
|title=[[SIL1]], the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology.
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=10.05.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29666155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992605
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
}}
==SIX3==
==INA==


* {{medline-title
* {{medline-title
|title=CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type.
|title=X[[RCC1]] and XPD genetic polymorphisms and susceptibility to age-related cataract: a meta-analysis.
|date=30.11.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265269
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384174
}}
}}
==SKAP2==
==INHBA==


* {{medline-title
* {{medline-title
|title=Longevity-related molecular pathways are subject to midlife "switch" in humans.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=08.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168962
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612641
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==SKI==
==INHBE==


* {{medline-title
* {{medline-title
|title=Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells.
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|date=04.2019
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29700792
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|full-text-url=https://sci-hub.do/10.1007/s11684-017-0586-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
}}
}}
==SLC15A1==
==INO80D==


* {{medline-title
* {{medline-title
|title=Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing.
|title=Whole exome sequencing implicates an [[INO80D]] mutation in a syndrome of aortic hypoplasia, premature atherosclerosis, and arterial stiffness.
|date=02.2019
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019300
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25122053
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3413-x
|full-text-url=https://sci-hub.do/10.1161/CIRCGENETICS.113.000233
}}
}}
==SLC15A2==
==INPP4B==


* {{medline-title
* {{medline-title
|title=Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing.
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|date=02.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019300
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3413-x
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
}}
}}
==SLC16A7==
==INPPL1==


* {{medline-title
* {{medline-title
|title=Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach.
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=23.10.2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33095951
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://sci-hub.do/10.1111/jdv.17014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
}}
==SLC19A1==
==INSR==


* {{medline-title
* {{medline-title
|title=Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer.
|title=The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover.
|date=30.03.2018
|date=20.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29682186
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28431247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406386
}}
}}
==SLC1A5==
==IP6K1==


* {{medline-title
* {{medline-title
|title=[[SLC1A5]] glutamine transporter is a target of [[MYC]] and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice.
|title=The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle.
|date=06.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909319
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552262
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516164
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746962
}}
}}
==SLC22A14==
==IP6K3==


* {{medline-title
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|title=Inositol Hexakisphosphate Kinase 3 Regulates Metabolism and Lifespan in Mice.
|date=01.2018
|date=31.08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27577108
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006000
}}
}}
==SLC22A23==
==IPMK==


* {{medline-title
* {{medline-title
|title=Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.
|title=Inositol Polyphosphate Multikinase ([i][[IPMK]][/i]), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity.
|date=11.2018
|date=08.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30744060
|full-text-url=https://sci-hub.do/10.1111/jgh.14149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410091
}}
}}
==SLC24A5==
==IRAK4==


* {{medline-title
* {{medline-title
|title=[A question of colour].
|title=The Expression Changes of Inflammasomes in the Aging Rat Kidneys.
|date=01.2018
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29384103
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26219846
|full-text-url=https://sci-hub.do/10.1051/medsci/20183401020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888379
}}
}}
==SLC26A2==
==IRF1==


* {{medline-title
* {{medline-title
|title=Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis.
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|date=01.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31914611
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|full-text-url=https://sci-hub.do/10.1096/fj.201901040RR
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
}}
}}
==SLC2A4==
==IRF5==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice.
|date=02.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28905935
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672072
}}
}}
==SLC30A1==
==IRX2==


* {{medline-title
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|title=Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence.
|date=01.12.2017
|date=28.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28105936
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249001
}}
}}
==SLC30A10==
==ISG15==


* {{medline-title
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|date=01.12.2017
|date=14.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
}}
}}
==SLC30A5==
==ISG20==


* {{medline-title
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|title=A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records.
|date=01.12.2017
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27764096
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072625
}}
}}
==SLC39A6==
==ISL1==


* {{medline-title
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|title=Deterioration of the Medial Olivocochlear Efferent System Accelerates Age-Related Hearing Loss in Pax2-Isl1 Transgenic Mice.
|date=01.12.2017
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25990412
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
|full-text-url=https://sci-hub.do/10.1007/s12035-015-9215-1
}}
}}
==SLC41A1==
==ISYNA1==


* {{medline-title
* {{medline-title
|title=Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis.
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=08.05.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31076559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
}}
==SLC52A2==
==ITCH==


* {{medline-title
* {{medline-title
|title=Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.
|title=Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing.
|date=01.11.2017
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26247845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808726
|full-text-url=https://sci-hub.do/10.1016/j.arr.2015.07.009
}}
}}
==SLC52A3==
==ITGA2==


* {{medline-title
* {{medline-title
|title=Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.
|title=[Clinical and genetic characteristics of long-livers in Moscow region].
|date=01.11.2017
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808726
 
}}
}}
==SLC7A11==
==ITGA3==


* {{medline-title
* {{medline-title
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|title=A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells.
|date=28.10.2017
|date=17.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32807231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430027
}}
}}
==SMAD1==
==ITGA5==


* {{medline-title
* {{medline-title
|title=TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands.
|title=Kaempferol alleviates the reduction of developmental competence during aging of porcine oocytes.
|date=26.11.2019
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779094
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31486245
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928867
|full-text-url=https://sci-hub.do/10.1111/asj.13280
}}
}}
==SMARCA5==
==ITGA6==


* {{medline-title
* {{medline-title
|title=The epigenetic regulator [[SIRT7]] guards against mammalian cellular senescence induced by ribosomal DNA instability.
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=13.07.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052228
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
}}
==SMARCB1==
==ITGB1==


* {{medline-title
* {{medline-title
|title=High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.
|title=Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.
|date=17.10.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29045843
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29599141
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2017.09.085
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.117.310685
}}
}}
==SMARCD1==
==ITGB2==


* {{medline-title
* {{medline-title
|title=Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells.
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|date=12.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30155609
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
}}
}}
==SMC2==
==ITGB4==


* {{medline-title
* {{medline-title
|title=The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence.
|title=[[ITGB4]] deficiency induces senescence of airway epithelial cells through p53 activation.
|date=10.11.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336977
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30636108
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.065
|full-text-url=https://sci-hub.do/10.1111/febs.14749
}}
}}
==SMC3==
==ITGB5==


* {{medline-title
* {{medline-title
|title=Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice.
|title=Differential DNA Methylation in Relation to Age and Health Risks of Obesity.
|date=10.2018
|date=24.07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26213922
|full-text-url=https://sci-hub.do/10.1007/s11655-018-2835-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581172
}}
}}
==SMC4==
==ITM2B==


* {{medline-title
* {{medline-title
|title=The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence.
|title=Intramembrane proteolysis within lysosomes.
|date=10.11.2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336977
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27143694
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.065
|full-text-url=https://sci-hub.do/10.1016/j.arr.2016.04.012
}}
}}
==SMN1==
==ITPKB==


* {{medline-title
* {{medline-title
|title=Changing respiratory expectations with the new disease trajectory of nusinersen treated spinal muscular atrophy [SMA] type 1.
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=09.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://sci-hub.do/10.1016/j.prrv.2018.07.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
}}
==SMN2==
==ITPR1==


* {{medline-title
* {{medline-title
|title=Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment.
|title=Age-associated repression of type 1 inositol 1, 4, 5-triphosphate receptor impairs muscle regeneration.
|date=01.11.2019
|date=21.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589162
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27658230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819103
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076452
}}
}}
==SMO==
==ITPR2==


* {{medline-title
* {{medline-title
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling.
|date=02.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923
}}
}}
==SMOX==
==JAG1==


* {{medline-title
* {{medline-title
|title=Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine.
|title=Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study.
|date=14.02.2018
|date=01.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29443878
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27616567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872171
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837042
}}
}}
==SMPD1==
==JAGN1==


* {{medline-title
* {{medline-title
|title=Alterations in Lipid Profile of the Aging Kidney Identified by MALDI Imaging Mass Spectrometry.
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|date=05.07.2019
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31244212
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
}}
}}
==SMYD2==
==JAM3==


* {{medline-title
* {{medline-title
|title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity.
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=10.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
}}
==SNAI2==
==JARID2==


* {{medline-title
* {{medline-title
|title=Reawakening of dormant estrogen-dependent human breast cancer cells by bone marrow stroma secretory senescence.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=17.08.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119678
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==SND1==
==JDP2==


* {{medline-title
* {{medline-title
|title=[Downregulation of [[SND1]] Expression Accelerates Cell Senescence of Human Diploid Fibroblasts 2BS via Modulating the SASP].
|title=Jun dimerization protein 2 controls hypoxia-induced replicative senescence via both the p16 -pRb and Arf-p53 pathways.
|date=05.2020
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32543144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29123987
|full-text-url=https://sci-hub.do/10.12182/20200560504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666393
}}
}}
==SOS1==
==JUNB==


* {{medline-title
* {{medline-title
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice.
|title=Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of [[JUNB]].
|date=21.01.2019
|date=19.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31806366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.11.145
}}
}}
==SOX11==
==JUP==


* {{medline-title
* {{medline-title
|title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
|title=From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration.
|date=10.08.2017
|date=22.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28185567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133493
}}
}}
==SOX13==
==KALRN==


* {{medline-title
* {{medline-title
|title=In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases.
|title=Age-dependent increase in Kalirin-9 and Kalirin-12 transcripts in human orbitofrontal cortex.
|date=12.2019
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27471199
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09834-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048532
}}
}}
==SOX4==
==KANSL1==


* {{medline-title
* {{medline-title
|title=Age-induced accumulation of methylmalonic acid promotes tumour progression.
|title=Koolen-de Vries Syndrome: Clinical Report of an Adult and Literature Review.
|date=09.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32814897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27852077
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2630-0
|full-text-url=https://sci-hub.do/10.1159/000452724
}}
}}
==SP1==
==KAT6B==


* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Aging-associated decrease in the histone acetyltransferase [[KAT6B]] is linked to altered hematopoietic stem cell differentiation.
|date=15.04.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32014431
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179256
}}
}}
==SP2==
==KCNAB3==


* {{medline-title
* {{medline-title
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography.
|title=Tracking age-correlated DNA methylation markers in the young.
|date=12.2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29933125
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.06.011
}}
}}
==SP7==
==KCNC3==


* {{medline-title
* {{medline-title
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird.
|date=06.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723
}}
}}
==SPATS2L==
==KCNC4==


* {{medline-title
* {{medline-title
|title=Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.
|title=Targeted deletion of [i]Kcne3[/i] impairs skeletal muscle function in mice.
|date=02.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585438
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818258
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472403
}}
}}
==SPG7==
==KCND3==


* {{medline-title
* {{medline-title
|title=Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration.
|title=Genetic determinants of P wave duration and PR segment.
|date=21.02.2018
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467464
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24850809
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141024
}}
}}
==SPHK1==
==KCNE3==


* {{medline-title
* {{medline-title
|title=Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina.
|title=Targeted deletion of [i]Kcne3[/i] impairs skeletal muscle function in mice.
|date=10.2019
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30997640
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425817
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472403
}}
}}
==SPHK2==
==KCNE4==


* {{medline-title
* {{medline-title
|title=Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.
|title=Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice.
|date=04.2019
|date=29.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30886000
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29844497
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446199
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974354
}}
}}
==SPON1==
==KCNH2==


* {{medline-title
* {{medline-title
|title=[[APOE]] influences working memory in non-demented elderly through an interaction with [[SPON1]] rs2618516.
|title=Targeted deletion of [i]Kcne3[/i] impairs skeletal muscle function in mice.
|date=07.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573041
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866309
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472403
}}
}}
==SPP1==
==KCNJ6==


* {{medline-title
* {{medline-title
|title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age.
|title=Genetic correlates of the development of theta event related oscillations in adolescents and young adults.
|date=04.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27847216
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456461
}}
}}
==SPRTN==
==KCNK2==


* {{medline-title
* {{medline-title
|title=Tandem Deubiquitination and Acetylation of [[SPRTN]] Promotes DNA-Protein Crosslink Repair and Protects against Aging.
|title=Brain age prediction using deep learning uncovers associated sequence variants.
|date=03.09.2020
|date=27.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32649882
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31776335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484104
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881321
}}
}}
==SRD5A2==
==KCNK4==


* {{medline-title
* {{medline-title
|title=Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II.
|title=Targeted deletion of [i]Kcne3[/i] impairs skeletal muscle function in mice.
|date=11.2020
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32125089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356343
|full-text-url=https://sci-hub.do/10.1111/jocd.13355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472403
}}
}}
==SRI==
==KCNQ1==


* {{medline-title
* {{medline-title
|title=The Role of Aging, Drug Dependence, and Hepatitis C Comorbidity in Alcoholism Cortical Compromise.
|title=Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis.
|date=01.05.2018
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29541774
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824446
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875381
|full-text-url=https://sci-hub.do/10.1136/bjsports-2014-094073
}}
}}
==SRL==
==KCNQ1DN==


* {{medline-title
* {{medline-title
|title=Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment.
|title=The EpiTect Methyl qPCR Assay as novel age estimation method in forensic biology.
|date=04-06.2020
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32432936
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27108355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250001
|full-text-url=https://sci-hub.do/10.1016/j.forsciint.2016.03.047
}}
}}
==SRM==
==KCNQ2==


* {{medline-title
* {{medline-title
|title=[Geriatric specificities of localized renal cell carcinoma].
|title=Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for [[GNG4]] and [[KCNQ2]] Genes.
|date=11.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771769
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338302
|full-text-url=https://sci-hub.do/10.1016/j.purol.2019.08.281
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098
}}
}}
==SRPK1==
==KCNQ4==


* {{medline-title
* {{medline-title
|title=[Age-related changes in the content of serine-arginine protein kinase 1 ([[SRPK1]]) in human dermis.]
|title=Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss.
|date=2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322729
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32327991
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160671
}}
==KCP==


* {{medline-title
|title=The kielin/chordin-like protein [[KCP]] attenuates nonalcoholic fatty liver disease in mice.
|date=01.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27514479
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142198
}}
}}
==SRSF1==
==KCTD12==


* {{medline-title
* {{medline-title
|title=Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
|title=The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort.
|date=09.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037605
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32970748
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2018.06.029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514036
}}
}}
==SRSF3==
==KDF1==


* {{medline-title
* {{medline-title
|title=Alternative polyadenylation dependent function of splicing factor [[SRSF3]] contributes to cellular senescence.
|title=The histological characteristics, age-related thickness change of skin, and expression of the HSPs in the skin during hair cycle in yak (Bos grunniens).
|date=04.03.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30835716
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28463974
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413005
}}
}}
==SRY==
==KDM2A==


* {{medline-title
* {{medline-title
|title=Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics.
|title=SIRT6 mono-ADP ribosylates [[KDM2A]] to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair.
|date=26.12.2017
|date=25.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29371932
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32584788
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768349
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343504
}}
}}
==SSBP2==
==KDM4A==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Structure-Based Discovery of a Selective [[KDM5A]] Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines.
|date=10.2019
|date=15.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30650517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360022
}}
}}
==ST18==
==KDM4B==


* {{medline-title
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|title=Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases.
|date=04.2016
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27114850
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809609
}}
}}
==ST6GAL1==
==KDM4C==


* {{medline-title
* {{medline-title
|title=Glycobiology of Aging.
|title=Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases.
|date=2018
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30779020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27114850
|full-text-url=https://sci-hub.do/10.1007/978-981-13-2835-0_17
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809609
}}
}}
==STC1==
==KDM5A==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Structure-Based Discovery of a Selective [[KDM5A]] Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines.
|date=02.2018
|date=15.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30650517
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360022
}}
}}
==STC2==
==KDM5B==


* {{medline-title
* {{medline-title
|title=Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and [[STC2]].
|title=Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases.
|date=05.12.2019
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31761296
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27114850
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904802
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809609
}}
}}
==STK3==
==KDR==


* {{medline-title
* {{medline-title
|title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence.
|title=Regulation of endothelial progenitor cell differentiation and function by dimethylarginine dimethylaminohydrolase 2 in an asymmetric dimethylarginine-independent manner.
|date=11.12.2018
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24764313
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934
|full-text-url=https://sci-hub.do/10.1002/cbin.10288
}}
}}
==STK32C==
==KIAA0319==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=The Dyslexia-susceptibility Protein [[KIAA0319]] Inhibits Axon Growth Through Smad2 Signaling.
|date=25.07.2018
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28334068
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905272
}}
}}
==STN1==
==KIF11==


* {{medline-title
* {{medline-title
|title=[[CTC1]]-[[STN1]] coordinates G- and C-strand synthesis to regulate telomere length.
|title=Bmk-1 regulates lifespan in Caenorhabditis elegans by activating hsp-16.
|date=08.2018
|date=07.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26299918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662456
}}
}}
==STOML2==
==KIF1A==


* {{medline-title
* {{medline-title
|title=Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=2017
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29201274
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==STX17==
==KIF3A==


* {{medline-title
* {{medline-title
|title=Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and [[XIAP]].
|title=Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease.
|date=01.10.2019
|date=01.09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24728190
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.05.017
|full-text-url=https://sci-hub.do/10.1093/hmg/ddu166
}}
}}
==SUCNR1==
==KIF5C==


* {{medline-title
* {{medline-title
|title=[The effect of Mexidol on cerebral mitochondriogenesis at a young age and during aging].
|title=Alteration of Motor Protein Expression Involved in Bidirectional Transport in Peripheral Blood Mononuclear Cells of Patients with Amyotrophic Lateral Sclerosis.
|date=2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105271
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26954557
|full-text-url=https://sci-hub.do/10.17116/jnevro202012001162
|full-text-url=https://sci-hub.do/10.1159/000443664
}}
}}
==SUGCT==
==KIF6==


* {{medline-title
* {{medline-title
|title=Knockout of the non-essential gene [[SUGCT]] creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
|title=Gene variants at [[FTO]], 9p21, and 2q36.3 are age-independently associated with myocardial infarction in Czech men.
|date=09.2020
|date=15.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31722069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26772723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426296
|full-text-url=https://sci-hub.do/10.1016/j.cca.2016.01.005
}}
}}
==SUMO1==
==KLB==


* {{medline-title
* {{medline-title
|title=[[SUMO1]]-conjugation is altered during normal aging but not by increased amyloid burden.
|title=Infants Uniquely Express High Levels of [[RBM3]] and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain.
|date=08.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29633471
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399610
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311128
}}
}}
==SUN1==
==KLF1==


* {{medline-title
* {{medline-title
|title=Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging.
|title=Mutant [[KLF1]] in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis.
|date=26.02.2019
|date=24.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30143664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109071
}}
}}
==SUN2==
==KLF10==


* {{medline-title
* {{medline-title
|title=Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging.
|title=Polymorphism rs7278468 is associated with Age-related cataract through decreasing transcriptional activity of the [[CRYAA]] promoter.
|date=26.02.2019
|date=17.03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26984531
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794711
}}
}}
==SURF1==
==KLF2==


* {{medline-title
* {{medline-title
|title=Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.
|title=[[KLF2]] induces the senescence of pancreatic cancer cells by cooperating with FOXO4 to upregulate p21.
|date=08.2018
|date=01.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696791
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31866399
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052393
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2019.111784
}}
}}
==SUZ12==
==KLF5==


* {{medline-title
* {{medline-title
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
|title=[[EGR1]] promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling.
|date=05.11.2018
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201921
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.06.010
}}
}}
==SV2B==
==KLF6==


* {{medline-title
* {{medline-title
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|title=Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence.
|date=10.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31824948
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882731
}}
}}
==SV2C==
==KLHL13==


* {{medline-title
* {{medline-title
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|title=Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle.
|date=10.2018
|date=29.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
|full-text-url=https://sci-hub.do/10.4238/gmr16029091
}}
}}
==SYNE1==
==KLHL22==


* {{medline-title
* {{medline-title
|title=Nesprin-1 impact on tumorigenic cell phenotypes.
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|date=02.2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31741263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05184-w
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
}}
}}
==SYNJ1==
==KPNA5==


* {{medline-title
* {{medline-title
|title=Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer's Disease.
|title=Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence.
|date=05.06.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29874583
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26029164
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040810
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432801
}}
}}
==SYNJ2==
==KRR1==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.
|date=25.07.2018
|date=29.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598835
}}
}}
==SYP==
==KRT15==


* {{medline-title
* {{medline-title
|title=The neuropeptide-12 improves recognition memory and neuronal plasticity of the limbic system in old rats.
|title=Extracellular proteoglycan decorin maintains human hair follicle stem cells.
|date=08.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29740871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320452
|full-text-url=https://sci-hub.do/10.1002/syn.22036
|full-text-url=https://sci-hub.do/10.1111/1346-8138.14678
}}
}}
==SYT1==
==KRT18==


* {{medline-title
* {{medline-title
|title=Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29670520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893842
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
==SYT7==
==KRT19==


* {{medline-title
* {{medline-title
|title=Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells.
|title=Characterization of Krt19  allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc.
|date=28.02.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30647108
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187500
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367206
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778700
}}
}}
==TAAR1==
==KRT5==


* {{medline-title
* {{medline-title
|title=Minimal Age-Related Alterations in Behavioral and Hematological Parameters in Trace Amine-Associated Receptor 1 ([[TAAR1]]) Knockout Mice.
|title=Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells.
|date=03.2020
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31399838
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27967234
|full-text-url=https://sci-hub.do/10.1007/s10571-019-00721-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449509
}}
}}
==TAF7==
==KTN1==


* {{medline-title
* {{medline-title
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|title=Common genetic variants influence human subcortical brain structures.
|date=22.01.2020
|date=09.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25607358
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366
}}
}}
==TAF7L==
==L3MBTL1==


* {{medline-title
* {{medline-title
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|title=Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis.
|date=22.01.2020
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824446
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
|full-text-url=https://sci-hub.do/10.1136/bjsports-2014-094073
}}
}}
==TARDBP==
==LAGE3==


* {{medline-title
* {{medline-title
|title=Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|date=06.2018
|date=11.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577934
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|full-text-url=https://sci-hub.do/10.1016/j.ajpath.2018.03.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
}}
}}
==TAS1R2==
==LAMA1==


* {{medline-title
* {{medline-title
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects.
|title=Laminin α1 regulates age-related mesangial cell proliferation and mesangial matrix accumulation through the TGF-β pathway.
|date=18.10.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24720953
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044709
}}
}}
==TBC1D1==
==LAMA2==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=[Alu insertion-deletion polymorphism of [[COL13A1]] and [[LAMA2]] genes: The analysis of association with longevity].
|date=02.2019
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369589
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
 
}}
}}
==TCERG1==
==LATS1==


* {{medline-title
* {{medline-title
|title=The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity.
|title=Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases [[MST1]] and MST2.
|date=17.07.2019
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31316054
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27940445
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210079
}}
}}
==TCF15==
==LDB2==


* {{medline-title
* {{medline-title
|title=Loss of Neurogenesis in Aging Hydra.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=05.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912256
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586502
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==TCF21==
==LDHC==


* {{medline-title
* {{medline-title
|title=Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3.
|title=The aged testis. A good model to find proteins involved in age-related changes of testis by proteomic analysis.
|date=22.06.2018
|date=01-02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29748384
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24597284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016453
 
}}
}}
==TCF7==
==LEF1==


* {{medline-title
* {{medline-title
|title=Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice.
|title=LncRNA H19 targets miR-22 to modulate H  O  -induced deregulation in nucleus pulposus cell senescence, proliferation, and ECM synthesis through Wnt signaling.
|date=04.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29206307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520849
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925424
|full-text-url=https://sci-hub.do/10.1002/jcb.26738
}}
}}
==TCTA==
==LGALS3==


* {{medline-title
* {{medline-title
|title=Exciplex-Forming Cohost for High Efficiency and High Stability Phosphorescent Organic Light-Emitting Diodes.
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|date=17.01.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29265796
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|full-text-url=https://sci-hub.do/10.1021/acsami.7b15034
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
}}
}}
==TDG==
==LGI1==


* {{medline-title
* {{medline-title
|title=lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/[[TDG]] axis.
|title=Antibody-associated CNS syndromes without signs of inflammation in the elderly.
|date=09.2019
|date=03.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282110
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28878050
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631166
}}
}}
==TDP1==
==LGR6==


* {{medline-title
* {{medline-title
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|title=Effect of defensins-containing eye cream on periocular rhytids and skin quality.
|date=12.06.2018
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32614135
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
|full-text-url=https://sci-hub.do/10.1111/jocd.13424
}}
}}
==TECPR2==
==LHB==


* {{medline-title
* {{medline-title
|title=Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging.
|title='Carriers of variant luteinizing hormone (V-LH) among 1593 Baltic men have significantly higher serum LH'.
|date=01-03.2019
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30681437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25820123
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000294
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832392
}}
}}
==TEF==
==LHCGR==


* {{medline-title
* {{medline-title
|title=Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response.
|title=Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats.
|date=10.2020
|date=11.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32189112
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050653
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09869-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590010
}}
}}
==TEP1==
==LIMK2==


* {{medline-title
* {{medline-title
|title=[Influence of Age on the Susceptibility of  Anopheles stephensi to Plasmodium berghei Infection].
|title=Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1.
|date=12.2016
|date=01-02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30141604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27678468
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227678
}}
}}
==TES==
==LIN28B==


* {{medline-title
* {{medline-title
|title=The Effects of Electrical Stimulation Pulse Duration on Lingual Palatal Pressure Measures During Swallowing in Healthy Older Adults.
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|date=08.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820657
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456514
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
}}
}}
==TET3==
==LINC00862==


* {{medline-title
* {{medline-title
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|date=02.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
}}
}}
==TFPI==
==LIPA==


* {{medline-title
* {{medline-title
|title=Identification of cardiovascular health gene variants related to longevity in a Chinese population.
|title=Influence of Habitual Physical Behavior - Sleeping, Sedentarism, Physical Activity - On Bone Health in Community-Dwelling Older People.
|date=07.09.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32897244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31037056
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476278
}}
}}
==TGDS==
==LMNB2==


* {{medline-title
* {{medline-title
|title=The evaluation and design of a short depression screening tool in Turkish older adults.
|title=Physiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear Edge.
|date=10.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29560848
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27602048
|full-text-url=https://sci-hub.do/10.1017/S1041610218000236
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993774
}}
}}
==TGFB1==
==LMO2==


* {{medline-title
* {{medline-title
|title=Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease.
|title=Aging-dependent DNA hypermethylation and gene expression of [[GSTM1]] involved in T cell differentiation.
|date=11.2017
|date=25.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28812215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28596482
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665708
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564710
}}
}}
==TGFBR1==
==LMX1A==


* {{medline-title
* {{medline-title
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|title=Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain.
|date=02.2019
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30318292
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234859
}}
}}
==TGFBR2==
==LOXL4==


* {{medline-title
* {{medline-title
|title=TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
|title=Blood Vessel Basement Membrane Alterations in Human Retinal Microaneurysms During Aging.
|date=08.05.2019
|date=01.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31068441
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28196225
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102613
|full-text-url=https://sci-hub.do/10.1167/iovs.16-19998
}}
}}
==TGM2==
==LPAR3==


* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Upregulated microRNA-15b alleviates ovarian cancer through inhitbition of the PI3K/Akt pathway by targeting [[LPAR3]].
|date=11.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140597
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://sci-hub.do/10.1002/jcp.28799
}}
}}
==THBS1==
==LRAT==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in [[RPE]] cells.
|date=15.11.2017
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24434119
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960355
}}
}}
==THBS4==
==LRCH1==


* {{medline-title
* {{medline-title
|title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment.
|title=Genetic determinants of P wave duration and PR segment.
|date=18.06.2019
|date=08.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24850809
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141024
}}
}}
==THEMIS==
==LRP2==


* {{medline-title
* {{medline-title
|title=Lifetime benefits of early detection and treatment of diabetic kidney disease.
|title=Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis.
|date=2019
|date=27.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31150444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544227
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.11.003
}}
}}
==THRB==
==LRP8==


* {{medline-title
* {{medline-title
|title=Age-associated increase of thyroid hormone receptor β gene promoter methylation coexists with decreased gene expression.
|title=SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating [[LRP8]] and ApoE.
|date=11.2018
|date=02.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733698
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31269452
|full-text-url=https://sci-hub.do/10.1080/07435800.2018.1469648
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.06.002
}}
}}
==TIMP2==
==LRRC34==


* {{medline-title
* {{medline-title
|title=The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma.
|title=The polygenic nature of telomere length and the anti-ageing properties of lithium.
|date=2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30252623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559463
|full-text-url=https://sci-hub.do/10.1080/09537104.2018.1514110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372618
}}
}}
==TINF2==
==LRRC8B==


* {{medline-title
* {{medline-title
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=04.2018
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==TJP1==
==LRRK1==


* {{medline-title
* {{medline-title
|title=Morphological and immunohistochemical characteristics of the equine corneal epithelium.
|title=Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.
|date=11.2019
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29056298
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693787
}}
}}
==TLR3==
==LTBP4==


* {{medline-title
* {{medline-title
|title=Repetitive [[TLR3]] activation in the lung induces skeletal muscle adaptations and cachexia.
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=06.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911410
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
}}
==TLR5==
==LY6D==


* {{medline-title
* {{medline-title
|title=Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.
|title=[[LY6D]]-induced macropinocytosis as a survival mechanism of senescent cells.
|date=08.2018
|date=09.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30089902
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168631
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0395-5
|full-text-url=https://sci-hub.do/10.1074/jbc.RA120.013500
}}
}}
==TLR6==
==LY86==


* {{medline-title
* {{medline-title
|title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.
|title=Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease.
|date=05.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31280115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732230
}}
}}
==TLR8==
==LYG1==


* {{medline-title
* {{medline-title
|title=[[TLR8]]-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy.
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|date=08.01.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30344014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050437
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
}}
}}
==TMEM119==
==LYST==


* {{medline-title
* {{medline-title
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=02.2019
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
==TNFSF15==
==MADD==


* {{medline-title
* {{medline-title
|title=Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens.
|title=Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-[[MADD]] locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=11.2018
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269026
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951664
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.09.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066205
}}
}}
==TNNI1==
==MAFB==


* {{medline-title
* {{medline-title
|title=Regular aerobic exercise-ameliorated troponin I carbonylation to mitigate aged rat soleus muscle functional recession.
|title=Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy.
|date=05.2019
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820991
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30605403
|full-text-url=https://sci-hub.do/10.1113/EP087564
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485685
}}
}}
==TNP1==
==MAGOHB==


* {{medline-title
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|title=Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescence.
|date=01.02.2019
|date=14.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26206181
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2015.07.010
}}
}}
==TNP2==
==MANF==


* {{medline-title
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|title=Age-dependent decrease in chaperone activity impairs [[MANF]] expression, leading to Purkinje cell degeneration in inducible SCA17 mice.
|date=01.02.2019
|date=22.01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462098
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863472
}}
}}
==TNPO3==
==MAP2K3==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Associations of [i][[MAP2K3]][/i] Gene Variants With Superior Memory in SuperAgers.
|date=10.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987172
}}
}}
==TOMM20==
==MAP3K11==


* {{medline-title
* {{medline-title
|title=Effect of aging on mitochondria and metabolism of bovine granulosa cells.
|title=Aberrant DNA Methylation in Keratoacanthoma.
|date=13.09.2020
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32921645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27788211
|full-text-url=https://sci-hub.do/10.1262/jrd.2020-071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082942
}}
}}
==TOP1==
==MAP3K5==


* {{medline-title
* {{medline-title
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|date=12.06.2018
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
}}
}}
==TOR2A==
==MAP4K3==


* {{medline-title
* {{medline-title
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
|title=[[MAP4K3]]/GLK in autoimmune disease, cancer and aging.
|date=05.06.2018
|date=22.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31640697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806545
}}
}}
==TP53INP1==
==MAPK10==


* {{medline-title
* {{medline-title
|title=[[TP53INP1]] deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=02.01.2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559202
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320535
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==TP53RK==
==MAPK11==


* {{medline-title
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|title=lncRNA ENSMUST00000134285 Increases [[MAPK11]] Activity, Regulating Aging-Related Myocardial Apoptosis.
|date=11.04.2019
|date=09.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415197
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
|full-text-url=https://sci-hub.do/10.1093/gerona/gly020
}}
}}
==TP73==
==MAPK13==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2017
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==TPH1==
==MAPK8==


* {{medline-title
* {{medline-title
|title=[i]Lactobacillus plantarum[/i] DR7 improved brain health in aging rats via the serotonin, inflammatory and apoptosis pathways.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=02.12.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33245015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://sci-hub.do/10.3920/BM2019.0200
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
==TPP1==
==MARCKSL1==


* {{medline-title
* {{medline-title
|title=FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping.
|title=[[MARCKSL1]] Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors.
|date=03.11.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33086033
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580842
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2020.10.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952351
}}
}}
==TPRKB==
==MARK1==


* {{medline-title
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=11.04.2019
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==TPX2==
==MAS1==


* {{medline-title
* {{medline-title
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|title=AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation.
|date=2018
|date=17.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667931
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940107
}}
}}
==TRAF2==
==MATN3==


* {{medline-title
* {{medline-title
|title=The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium.
|title=Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis.
|date=12.2019
|date=19.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31042012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31963938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013758
}}
}}
==TRAP1==
==MATR3==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Heterogeneity of Matrin 3 in the developing and aging murine central nervous system.
|date=2019
|date=01.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26878116
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832027
}}
}}
==TRAV1-2==
==MBD2==


* {{medline-title
* {{medline-title
|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers.
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|date=05.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
}}
}}
==TRAV27==
==MBL2==


* {{medline-title
* {{medline-title
|title=Perturbed CD8  T cell immunity across universal influenza epitopes in the elderly.
|title=Recurrent respiratory tract infections (RRTI) in the elderly: A late onset mild immunodeficiency?
|date=02.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28487087
|full-text-url=https://sci-hub.do/10.1189/jlb.5MA0517-207R
|full-text-url=https://sci-hub.do/10.1016/j.clim.2017.05.008
}}
}}
==TRBV19==
==MC4R==


* {{medline-title
* {{medline-title
|title=Perturbed CD8  T cell immunity across universal influenza epitopes in the elderly.
|title=Melanocortin-4 receptor rs17782313 polymorphisms are associated with serum triglycerides in older Chinese women.
|date=02.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26965781
|full-text-url=https://sci-hub.do/10.1189/jlb.5MA0517-207R
|full-text-url=https://sci-hub.do/10.6133/apjcn.2016.25.1.18
}}
}}
==TRIB2==
==MCF2L==


* {{medline-title
* {{medline-title
|title=[[TRIB2]] functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=12.12.2018
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291992
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==TRIB3==
==MCM4==


* {{medline-title
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=2018
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
}}
==TRIM21==
==MCM5==


* {{medline-title
* {{medline-title
|title=[[TRIM21]] overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma.
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=2020
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32064156
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017742
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
}}
==TRIM27==
==MCM6==


* {{medline-title
* {{medline-title
|title=[[TRIM27]] Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination.
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=04.12.2020
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33251042
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666371
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
}}
==TRIM28==
==MCUR1==


* {{medline-title
* {{medline-title
|title=Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau.
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|date=04.06.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29863470
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993537
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
}}
}}
==TRIP13==
==MDK==


* {{medline-title
* {{medline-title
|title=BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=02.01.2020
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31738183
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934189
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
==TRPC1==
==MDM4==


* {{medline-title
* {{medline-title
|title=Ca  entry via [[TRPC1]] is essential for cellular differentiation and modulates secretion via the SNARE complex.
|title=Germline genetics of the p53 pathway affect longevity in a gender specific manner.
|date=01.07.2019
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182642
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24654968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397
|full-text-url=https://sci-hub.do/10.2174/1874609807666140321150751
}}
}}
==TRPC7==
==MDN1==


* {{medline-title
* {{medline-title
|title=Nociceptive transient receptor potential canonical 7 ([[TRPC7]]) mediates aging-associated tumorigenesis induced by ultraviolet B.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=01.2020
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31755176
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974716
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
==TRPM6==
==ME3==


* {{medline-title
* {{medline-title
|title=Role of kinase-coupled TRP channels in mineral homeostasis.
|title=Acceleration of age-associated methylation patterns in HIV-1-infected adults.
|date=04.2018
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25807146
|full-text-url=https://sci-hub.do/10.1016/j.pharmthera.2017.11.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373843
}}
}}
==TRPS1==
==MECOM==


* {{medline-title
* {{medline-title
|title=miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence.
|title=Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.
|date=01.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603369
|full-text-url=https://sci-hub.do/10.1002/jcb.28862
|full-text-url=https://sci-hub.do/10.1111/jgh.14149
}}
}}
==TRPV5==
==MED25==


* {{medline-title
* {{medline-title
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|title=The [i]HAC1[/i] histone acetyltransferase promotes leaf senescence and regulates the expression of [i]ERF022[/i].
|date=01.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710649
}}
}}
==TRPV6==
==MED28==


* {{medline-title
* {{medline-title
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|title=Redox regulation of the [[MED28]] and MED32 mediator subunits is important for development and senescence.
|date=01.2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26195288
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
|full-text-url=https://sci-hub.do/10.1007/s00709-015-0853-y
}}
}}
==TSG101==
==MEFV==


* {{medline-title
* {{medline-title
|title=Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging.
|title=The grandfather's fever.
|date=01.09.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220525
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31401792
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116582
|full-text-url=https://sci-hub.do/10.1007/s10067-019-04741-9
}}
}}
==TSHB==
==MEIS2==


* {{medline-title
* {{medline-title
|title=Adipose [[TSHB]] in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence.
|title=Pbx1 is required for adult subventricular zone neurogenesis.
|date=2018
|date=01.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448824
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27226325
|full-text-url=https://sci-hub.do/10.1159/000495170
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958316
}}
}}
==TSHR==
==MELK==


* {{medline-title
* {{medline-title
|title=TSH-independent release of thyroid hormones through cold exposure in aging rats.
|title=[[MELK]]-T1, a small-molecule inhibitor of protein kinase [[MELK]], decreases DNA-damage tolerance in proliferating cancer cells.
|date=27.10.2017
|date=02.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163760
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26431963
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685681
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643329
}}
}}
==TSPYL5==
==MERTK==


* {{medline-title
* {{medline-title
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=03.2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==TTL==
==MESP1==


* {{medline-title
* {{medline-title
|title=Longitudinal Associations of Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio with Biomarkers of Oxidative Stress in Older Adults: Results of a Large Cohort Study.
|title=Simulated Microgravity Exerts an Age-Dependent Effect on the Differentiation of Cardiovascular Progenitors Isolated from the Human Heart.
|date=2020
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31986512
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26161778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498633
}}
}}
==TXN==
==MEST==


* {{medline-title
* {{medline-title
|title=Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice.
|title=Improving specific autobiographical memory in older adults: impacts on mood, social problem solving, and functional limitations.
|date=15.11.2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29141658
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825508
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688691
|full-text-url=https://sci-hub.do/10.1080/13825585.2017.1365815
}}
==MFAP4==
 
* {{medline-title
|title=The role of microfibrillar-associated protein 4 ([[MFAP4]]) in the formation and function of splenic compartments during embryonic and adult life.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26899386
|full-text-url=https://sci-hub.do/10.1007/s00441-016-2374-1
}}
==MFSD2A==
 
* {{medline-title
|title=Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease.
|date=20.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31861865
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981746
}}
==MIB1==
 
* {{medline-title
|title=Immunohistochemical detection of senescence markers in human sarcomas.
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31899047
|full-text-url=https://sci-hub.do/10.1016/j.prp.2019.152800
}}
}}
==TXNDC5==
==MICB==


* {{medline-title
* {{medline-title
Строка 13 175: Строка 13 773:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==TXNRD1==
==MICU1==


* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|date=06.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
}}
}}
==TYK2==
==MLH3==


* {{medline-title
* {{medline-title
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|title=Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes.
|date=04.2018
|date=19.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942922
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679441
}}
}}
==TYROBP==
==MLST8==


* {{medline-title
* {{medline-title
|title=[[TREM2]] triggers microglial density and age-related neuronal loss.
|title=Genetic variants near [[MLST8]] and [[DHX57]] affect the epigenetic age of the cerebellum.
|date=03.2019
|date=02.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548312
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26830004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740877
}}
}}
==U2AF1==
==MMP10==


* {{medline-title
* {{medline-title
|title=Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs.
|title=Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates.
|date=05.03.2020
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32141009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26859687
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01509-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844783
}}
}}
==UACA==
==MMP14==


* {{medline-title
* {{medline-title
|title=Knockdown of [i][[UACA]][/i] inhibitsproliferation and invasion and promotes senescence of hepatocellular carcinoma cells.
|title=Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells.
|date=2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31949867
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962967
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755030
}}
}}
==UBB==
==MMP8==


* {{medline-title
* {{medline-title
|title=Different Expression Levels of Human Mutant Ubiquitin B  ([[UBB]] ) Can Modify Chronological Lifespan or Stress Resistance of [i]Saccharomyces cerevisiae[/i].
|title=Bone biology-related gingival transcriptome in ageing and periodontitis in non-human primates.
|date=2018
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29950972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26859687
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008557
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844783
}}
}}
==UBC==
==MOG==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=ASSOCIATION OF PREVASCUL[[AR]] [[VIT]]REOUS FISSURES AND CISTERNS WI[[TH]] [[VIT]]REOUS DEGENERATION AS ASSESSED BY SWEPT SOURCE OPTICAL COHE[[REN]]CE TO[[MOG]]RAPHY.
|date=2019
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25874366
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://sci-hub.do/10.1097/IAE.0000000000000540
}}
==MORF4L1==
 
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
==UBE2E3==
==MPC1==


* {{medline-title
* {{medline-title
|title=Loss of the ubiquitin conjugating enzyme [[UBE2E3]] induces cellular senescence.
|title=Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training.
|date=07.2018
|date=01.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29879550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27221120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967149
}}
}}
==UBE3A==
==MPG==


* {{medline-title
* {{medline-title
|title=Delayed loss of [[UBE3A]] reduces the expression of Angelman syndrome-associated phenotypes.
|title=Menoprogen, a TCM Herbal Formula for Menopause, Increases Endogenous E2 in an Aged Rat Model of Menopause by Reducing Ovarian Granulosa Cell Apoptosis.
|date=2019
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31143434
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26981526
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532248
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769746
}}
}}
==UBE4B==
==MPHOSPH6==


* {{medline-title
* {{medline-title
|title=CircRNAs in the tree shrew ([i]Tupaia belangeri[/i]) brain during postnatal development and aging.
|title=Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length.
|date=30.04.2018
|date=05.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29723158
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058826
}}
}}
==UBTF==
==MPL==


* {{medline-title
* {{medline-title
|title=Age-associated dysregulation of protein metabolism in the mammalian oocyte.
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender.
|date=12.2017
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994181
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676066
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0
}}
}}
==UCHL1==
==MPP4==


* {{medline-title
* {{medline-title
|title=Abolishing [[UCHL1]]'s hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice.
|title=DNA damage tolerance in hematopoietic stem and progenitor cells in mice.
|date=04.11.2020
|date=15.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33159930
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28761001
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2020.113524
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565453
}}
}}
==UCHL3==
==MPST==


* {{medline-title
* {{medline-title
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|title=Methionine restriction leads to hyperhomocysteinemia and alters hepatic H S production capacity in Fischer-344 rats.
|date=12.06.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30367932
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.10.004
}}
}}
==UCN==
==MPV17==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=The Human Mitochondrial DNA Depletion Syndrome Gene [[MPV17]] Encodes a Non-selective Channel That Modulates Membrane Potential.
|date=15.11.2018
|date=29.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25861990
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447960
}}
}}
==UCN3==
==MRC1==


* {{medline-title
* {{medline-title
|title=Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise-induced threshold shift.
|title=Myocardial Infarction Superimposed on Aging: MMP-9 Deletion Promotes M2 Macrophage Polarization.
|date=08.2019
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31270820
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25878031
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852351
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175450
}}
}}
==UCP3==
==MRO==


* {{medline-title
* {{medline-title
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats.
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats].
|date=01.2018
|date=08.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110
}}
}}
==UGT2B28==
==MRTFA==


* {{medline-title
* {{medline-title
|title=Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a [[UGT2B28]] genomic variation.
|title=Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse.
|date=05.12.2019
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31805979
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30422822
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355303
}}
}}
==UGT2B7==
==MS4A1==


* {{medline-title
* {{medline-title
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|date=05.2019
|date=19.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
}}
}}
==UHRF1==
==MS4A4A==


* {{medline-title
* {{medline-title
|title=MLL3 promotes the senescence of esophageal squamous cell carcinoma.
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=2019
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30881012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
}}
==ULK2==
==MS4A6A==


* {{medline-title
* {{medline-title
|title=miR-26a suppresses autophagy in swine Sertoli cells by targeting [[ULK2]].
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=08.2018
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29761550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://sci-hub.do/10.1111/rda.13177
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
==UMOD==
==MSH3==


* {{medline-title
* {{medline-title
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes.
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=03.2019
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
}}
==UNG==
==MSH5==


* {{medline-title
* {{medline-title
|title=[[UNG]]-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.
|title=Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease.
|date=01.05.2018
|date=11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29717169
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26193622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853027
}}
}}
==UPF1==
==MSH6==


* {{medline-title
* {{medline-title
|title=Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity.
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=21.08.2017
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28824175
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563511
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
}}
==UQCRC2==
==MSN==


* {{medline-title
* {{medline-title
|title=Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10).
|title=The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease.
|date=06.2018
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27818324
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214572
}}
}}
==USF1==
==MSR1==


* {{medline-title
* {{medline-title
|title=The rs2516839 variation of [[USF1]] gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+ study.
|title=Role of TGFβ signaling in the pathogenesis of Alzheimer's disease.
|date=01.2019
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30203836
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26578886
|full-text-url=https://sci-hub.do/10.1111/ahg.12282
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623426
}}
}}
==USF2==
==MSRA==


* {{medline-title
* {{medline-title
|title=Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice.
|title=Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis.
|date=15.10.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30084918
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30456853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351846
}}
}}
==USP14==
==MT1B==


* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Pharmacological advantages of melatonin in immunosenescence by improving activity of T lymphocytes.
|date=07.2018
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27533940
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946322
}}
}}
==USP15==
==MT1M==


* {{medline-title
* {{medline-title
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i].
|title=A novel strain of Lactobacillus mucosae isolated from a Gaotian villager improves in vitro and in vivo antioxidant as well as biological properties in D-galactose-induced aging mice.
|date=29.05.2018
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26709186
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047
|full-text-url=https://sci-hub.do/10.3168/jds.2015-10265
}}
}}
==USP28==
==MT3==


* {{medline-title
* {{medline-title
|title=Genetic interrogation of replicative senescence uncovers a dual role for [[USP28]] in coordinating the p53 and [[GATA4]] branches of the senescence program.
|title=Age-related changes of metallothionein 1/2 and metallothionein 3 expression in rat brain.
|date=01.10.2017
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27939232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710139
|full-text-url=https://sci-hub.do/10.1016/j.crvi.2016.11.003
}}
}}
==USP30==
==MTBP==


* {{medline-title
* {{medline-title
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i].
|title=Multiomics Approach to Novel Therapeutic Targets for Cancer and Aging-Related Diseases: Role of Sld7 in Yeast Aging Network.
|date=29.05.2018
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28118095
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047
|full-text-url=https://sci-hub.do/10.1089/omi.2016.0157
}}
}}
==USP7==
==MTNR1A==


* {{medline-title
* {{medline-title
|title=Deubiquitinase [[USP7]] regulates [i]Drosophila[/i] aging through ubiquitination and autophagy.
|title=Influence of melatonin receptor 1A gene polymorphisms on seasonal reproduction in Sarda ewes with different body condition scores and ages.
|date=20.11.2020
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33221768
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25132211
|full-text-url=https://sci-hub.do/10.18632/aging.104067
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2014.07.022
}}
}}
==USP8==
==MUC1==


* {{medline-title
* {{medline-title
|title=Inhibition of the deubiquitinase [[USP8]] corrects a Drosophila [[PINK1]] model of mitochondria dysfunction.
|title=Sensitivity of neoplastic cells to senescence unveiled under standard cell culture conditions.
|date=04.2019
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25964555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467245
 
}}
}}
==VAMP2==
==MUC7==


* {{medline-title
* {{medline-title
|title=Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission.
|title=Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model.
|date=01.08.2018
|date=24.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29950309
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31554163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068464
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835954
}}
}}
==VAMP8==
==MUL1==


* {{medline-title
* {{medline-title
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells.
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models.
|date=2018
|date=28.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415
}}
}}
==VASH1==
==MUTYH==


* {{medline-title
* {{medline-title
|title=Double-Face of Vasohibin-1 for the Maintenance of Vascular Homeostasis and Healthy Longevity.
|title=Cholangiocyte senescence caused by lysophosphatidylcholine as a potential implication in carcinogenesis.
|date=01.06.2018
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29398681
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25921542
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005230
|full-text-url=https://sci-hub.do/10.1002/jhbp.256
}}
}}
==VASP==
==MX1==


* {{medline-title
* {{medline-title
|title=Reversal of Aging-Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein-Protein Interfaces.
|title=Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection.
|date=18.07.2018
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021807
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230210
}}
}}
==VCL==
==MYBBP1A==


* {{medline-title
* {{medline-title
|title=The effects of different preservation methods on ide (Leuciscus idus) sperm and the longevity of sperm movement.
|title=The protein-interaction network with functional roles in tumorigenesis, neurodegeneration, and aging.
|date=04.2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397922
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27699588
|full-text-url=https://sci-hub.do/10.1016/j.cryobiol.2018.01.014
|full-text-url=https://sci-hub.do/10.1007/s11010-016-2836-5
}}
}}
==VCP==
==MYBL2==


* {{medline-title
* {{medline-title
|title=The role of air pollution and lung function in cognitive impairment.
|title=Molecular mechanism of G  arrest and cellular senescence induced by LEE011, a novel [[CDK4]]/CDK6 inhibitor, in leukemia cells.
|date=02.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467204
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286417
|full-text-url=https://sci-hub.do/10.1183/13993003.01963-2017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340031
}}
}}
==VEGFA==
==MYBPC1==


* {{medline-title
* {{medline-title
|title=APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease.
|title=Myosin Binding Protein-C Slow Phosphorylation is Altered in Duchenne Dystrophy and Arthrogryposis Myopathy in Fast-Twitch Skeletal Muscles.
|date=03.2020
|date=19.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31791659
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26287277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642557
}}
}}
==VEGFC==
==MYCN==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells.
|date=02.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920463
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947931
}}
}}
==VEGFD==
==MYCNOS==


* {{medline-title
* {{medline-title
|title=Single-Arm Resistance Training Study to Determine the Relationship between Training Outcomes and Muscle Growth Factor mRNAs in Older Adults Consuming Numerous Medications and Supplements.
|title=Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis.
|date=2018
|date=26.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29380855
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657277
|full-text-url=https://sci-hub.do/10.1007/s12603-017-0913-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831999
}}
}}
==VGLL4==
==MYH10==


* {{medline-title
* {{medline-title
|title=The lncRNA MEG3/miR-16-5p/[[VGLL4]] regulatory axis is involved in etoposide-induced senescence of tumor cells.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=03.11.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33141998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://sci-hub.do/10.1002/jgm.3291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==VHLL==
==MYH9==


* {{medline-title
* {{medline-title
|title=The Monetary Valuation of Lifetime Health Improvement and Life Expectancy Gains in Turkey.
|title=Estimated glomerular filtration rate (eGFR), 25(OH) D3, chronic kidney disease (CKD), the [[MYH9]] (myosin heavy chain 9) gene in old and very elderly people.
|date=29.09.2017
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28961227
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26152646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664652
|full-text-url=https://sci-hub.do/10.1007/s11255-015-1041-x
}}
}}
==VIPR2==
==MYLPF==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle.
|date=15.11.2018
|date=15.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004
}}
}}
==VPREB3==
==MYNN==


* {{medline-title
* {{medline-title
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=19.01.2019
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
}}
==VPS13C==
==MYO1F==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|date=04.07.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
}}
}}
==VPS13D==
==MYO5B==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|date=04.07.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
}}
}}
==VPS29==
==MYOC==


* {{medline-title
* {{medline-title
|title=Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development.
|title=Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
|date=16.01.2019
|date=28.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389787
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311499
}}
}}
==VPS35==
==MYOCD==


* {{medline-title
* {{medline-title
|title=Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development.
|title=Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a.
|date=16.01.2019
|date=01.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27634012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130548
}}
}}
==VSIG4==
==MYOF==


* {{medline-title
* {{medline-title
|title=Immune checkpoint protein [[VSIG4]] as a biomarker of aging in murine adipose tissue.
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|date=10.2020
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856419
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
}}
}}
==WAS==
==MYOG==


* {{medline-title
* {{medline-title
|title=Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number.
|title=Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice.
|date=09.11.2017
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129830
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27224259
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723686
|full-text-url=https://sci-hub.do/10.1111/dgd.12290
}}
}}
==WASL==
==MYSM1==


* {{medline-title
* {{medline-title
|title=Loss of Wasl improves pancreatic cancer outcome.
|title=[[MYSM1]] Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan.
|date=21.05.2020
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434991
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33240758
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259520
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675055
}}
}}
==WDR5==
==MYT1==


* {{medline-title
* {{medline-title
|title=Inhibition of the H3K4 methyltransferase MLL1/[[WDR5]] complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16 .
|title=ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the [[MYT1]]-Egln3-Sirt1 Axis.
|date=11.2019
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570196
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33038325
|full-text-url=https://sci-hub.do/10.1016/j.kint.2019.06.021
|full-text-url=https://sci-hub.do/10.1016/j.ymthe.2020.09.037
}}
}}
==WDR73==
==NACA==


* {{medline-title
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|title=Age and Sex Are Strongly Correlated to the Rate and Type of Mountain Injuries Requiring Search and Rescue Missions.
|date=11.04.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31699646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
|full-text-url=https://sci-hub.do/10.1016/j.wem.2019.06.016
}}
}}
==WFDC2==
==NAIP==


* {{medline-title
* {{medline-title
|title=Differences in biomarkers and molecular pathways according to age for patients with HFrEF.
|title=Protective effect of xanthohumol against age-related brain damage.
|date=01.10.2020
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002110
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154
|full-text-url=https://sci-hub.do/10.1093/cvr/cvaa279
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011
}}
}}
==WFIKKN1==
==NBPF6==


* {{medline-title
* {{medline-title
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.
|title=Genomewide Association Scan of a Mortality Associated Endophenotype for a Long and Healthy Life in the Long Life Family Study.
|date=01.01.2019
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28329217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861859
}}
}}
==WFIKKN2==
==NCAM1==


* {{medline-title
* {{medline-title
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.
|title=Resistance Training Enhances Skeletal Muscle Innervation Without Modifying the Number of Satellite Cells or their Myofiber Association in Obese Older Adults.
|date=01.01.2019
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26447161
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018557
}}
}}
==WLS==
==NCK2==


* {{medline-title
* {{medline-title
|title=Evaluation of three statistical prediction models for forensic age prediction based on DNA methylation.
|title=Genetic associations with age of menopause in familial longevity.
|date=05.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.02.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==WNK1==
==NCOR2==


* {{medline-title
* {{medline-title
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=10.2018
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==WNK4==
==NDN==


* {{medline-title
* {{medline-title
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2.
|title=The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging.
|date=10.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087674
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066563
}}
}}
==WNT10A==
==NDP==


* {{medline-title
* {{medline-title
|title=Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development.
|title=Association between Cognitive Status before Surgery and Outcomes in Elderly Patients with Hip Fracture in a Dedicated Orthogeriatric Care Pathway.
|date=01.04.2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31964233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27911302
|full-text-url=https://sci-hub.do/10.1089/scd.2019.0260
|full-text-url=https://sci-hub.do/10.3233/JAD-160655
}}
}}
==WNT16==
==NDUFA9==


* {{medline-title
* {{medline-title
|title=Inducible [i]Wnt16[/i] inactivation: [[WNT16]] regulates cortical bone thickness in adult mice.
|title=Preservation of skeletal muscle mitochondrial content in older adults: relationship between mitochondria, fibre type and high-intensity exercise training.
|date=05.2018
|date=01.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29530924
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28251664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451733
}}
}}
==WNT3==
==NDUFAB1==


* {{medline-title
* {{medline-title
|title=Role of CD133 Molecule in Wnt Response and Renal Repair.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=03.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29431914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==WNT5A==
==NDUFS3==


* {{medline-title
* {{medline-title
|title=[[WNT5A]] supports viability of senescent human dental follicle cells.
|title=Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10).
|date=05.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30406314
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477336
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3467-9
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.025
}}
}}
==WNT7A==
==NDUFS7==


* {{medline-title
* {{medline-title
|title=Exogenous Expression of [[WNT7A]] in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents.
|title=Nod-like receptor pyrin containing 3 ([[NLRP3]]) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation.
|date=2020
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26540403
|full-text-url=https://sci-hub.do/10.2174/1871520620666200521114100
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2015.10.015
}}
}}
==WT1==
==NDUFS8==


* {{medline-title
* {{medline-title
|title=Age and weight at first mating affects plasma leptin concentration but no effects on reproductive performance of gilts.
|title=Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity.
|date=09.2019
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31602307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32773682
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494633
}}
}}
==WWP1==
==NDUFV1==


* {{medline-title
* {{medline-title
|title=The ubiquitin ligase [[WWP1]] contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart.
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
|date=01.10.2020
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32822210
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717125
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201
}}
}}
==XDH==
==NEBL==


* {{medline-title
* {{medline-title
|title=Enhancing xanthine dehydrogenase activity is an effective way to delay leaf senescence and increase rice yield.
|title=Isolation and characterization of the human immature osteoblast culture system from the alveolar bones of aged donors for bone regeneration therapy.
|date=11.03.2020
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25241883
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065298
|full-text-url=https://sci-hub.do/10.1517/14712598.2014.960387
}}
}}
==XG==
==NEDD4==


* {{medline-title
* {{medline-title
|title=The effect of administration media on palatability and ease of swallowing of multiparticulate formulations.
|title=Estrogen receptor β, a regulator of androgen receptor signaling in the mouse ventral prostate.
|date=15.11.2018
|date=09.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30170024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439009
|full-text-url=https://sci-hub.do/10.1016/j.ijpharm.2018.08.021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441728
}}
}}
==XPC==
==NEIL2==


* {{medline-title
* {{medline-title
|title=MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene [[XPC]] in Age-related Cataract.
|title=Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation.
|date=12.10.2018
|date=09.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30315181
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26245904
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185952
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598976
}}
}}
==XPO1==
==NEIL3==


* {{medline-title
* {{medline-title
|title=Nuclear Export Inhibition Enhances HLH-30/[[TFEB]] Activity, Autophagy, and Lifespan.
|title=Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin.
|date=15.05.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768192
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31167196
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991088
|full-text-url=https://sci-hub.do/10.1159/000500091
}}
}}
==XRCC4==
==NEK2==


* {{medline-title
* {{medline-title
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.
|title=Upregulation of [[FOXM1]] leads to diminished drug sensitivity in myeloma.
|date=2018
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463534
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249818
}}
}}
==YES1==
==NEK9==


* {{medline-title
* {{medline-title
|title=Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies.
|title=Effect of sex, age and genetics on crossover interference in cattle.
|date=20.10.2018
|date=28.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30341976
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27892966
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224233
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125268
}}
}}
==ZBTB16==
==NELL1==


* {{medline-title
* {{medline-title
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
|title=Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology.
|date=06.2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28719597
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773415
}}
}}
==ZFHX3==
==NEU1==


* {{medline-title
* {{medline-title
|title=Shift work, DNA methylation and epigenetic age.
|title=Sialylation regulates myofibroblast differentiation of human skin fibroblasts.
|date=01.10.2019
|date=18.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30879037
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28420408
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857743
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395757
}}
}}
==ZFPM2==
==NF2==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression.
|date=15.11.2018
|date=21.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27818180
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519326
}}
}}
==ZNF207==
==NFIA==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Cell-type-specific expression of [[NFIX]] in the developing and adult cerebellum.
|date=02.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878595
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://sci-hub.do/10.1007/s00429-016-1340-8
}}
}}
==ZNF396==
==NFIL3==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=[Identification of single nucleotide polymorphisms in centenarians].
|date=15.11.2018
|date=05-06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26541311
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1016/j.regg.2015.09.006
}}
}}
==ZNF467==
==NFIX==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Cell-type-specific expression of [[NFIX]] in the developing and adult cerebellum.
|date=15.11.2018
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878595
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1007/s00429-016-1340-8
}}
}}
==ZNF521==
==NFKB2==


* {{medline-title
* {{medline-title
|title=Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells.
|title=Partial sleep deprivation activates the DNA damage response (DDR) and the senescence-associated secretory phenotype (SASP) in aged adult humans.
|date=21.06.2019
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31227697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26336034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588633
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679552
}}
==NFKBIA==
 
* {{medline-title
|title=Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging.
|date=28.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198498
}}
==NIN==
 
* {{medline-title
|title=Increased macromolecular damage due to oxidative stress in the neocortex and hippocampus of W[[NIN]]/Ob, a novel rat model of premature aging.
|date=06.06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24709042
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2014.03.040
}}
==NKAP==
 
* {{medline-title
|title=[[NKAP]] Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31632967
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783958
}}
==NKIRAS2==
 
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
==NKX2-1==
 
* {{medline-title
|title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685
|full-text-url=https://sci-hub.do/10.1134/S0006297915030062
}}
==NKX2-5==
 
* {{medline-title
|title=Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart.
|date=07.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30663680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207148
}}
==NKX6-1==
 
* {{medline-title
|title=The dynamic methylome of islets in health and disease.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768570
}}
==NLRC5==
 
* {{medline-title
|title=Methylation of the genes ROD1, [[NLRC5]], and HKR1 is associated with aging in Hainan centenarians.
|date=02.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29394898
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797414
}}
==NLRP5==
 
* {{medline-title
|title=Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa.
|date=02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26197995
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712099
}}
==NLRP6==
 
* {{medline-title
|title=LRP6 targeting suppresses gastric tumorigenesis via P14 -Mdm2-P53-dependent cellular senescence.
|date=19.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29340077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762345
}}
==NMI==
 
* {{medline-title
|title=Age-Dependent Control of Shoulder Muscles During a Reach-and-Lift Task.
|date=10.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31825888
|full-text-url=https://sci-hub.do/10.1123/japa.2019-0055
}}
==NMNAT3==
 
* {{medline-title
|title=Restoration of Mitochondrial NAD  Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells.
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27428041
|full-text-url=https://sci-hub.do/10.1002/stem.2460
}}
==NMRK2==
 
* {{medline-title
|title=Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283350
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156423
}}
==NMUR1==
 
* {{medline-title
|title=[Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules].
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31685733
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00149
}}
==NOBOX==
 
* {{medline-title
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|date=18.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
}}
==NOD2==
 
* {{medline-title
|title=Molecular modeling in the age of clinical genomics, the enterprise of the next generation.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28204942
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529140
}}
==NOL12==
 
* {{medline-title
|title=[[NOL12]] Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
|date=15.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549468
}}
==NOLC1==
 
* {{medline-title
|title=Enhanced [[NOLC1]] promotes cell senescence and represses hepatocellular carcinoma cell proliferation by disturbing the organization of nucleolus.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28493459
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506443
}}
==NOTCH4==
 
* {{medline-title
|title=Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH.
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595581
}}
==NPBWR1==
 
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
==NPFFR2==
 
* {{medline-title
|title=Genome-wide association study for longevity with whole-genome sequencing in 3 cattle breeds.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27289149
|full-text-url=https://sci-hub.do/10.3168/jds.2015-10697
}}
==NPPB==
 
* {{medline-title
|title=Chloride channels are involved in sperm motility and are downregulated in spermatozoa from patients with asthenozoospermia.
|date=07-08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27270342
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507086
}}
==NPRL2==
 
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
}}
==NPRL3==
 
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
}}
==NPY1R==
 
* {{medline-title
|title=[[NPY]]/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging?
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26086271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590601
}}
==NPY2R==
 
* {{medline-title
|title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460
}}
==NPY5R==
 
* {{medline-title
|title=[[NPY]]/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging?
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26086271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590601
}}
==NQO2==
 
* {{medline-title
|title=The ontogeny and population variability of human hepatic dihydronicotinamide riboside:quinone oxidoreductase ([[NQO2]]).
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28346733
|full-text-url=https://sci-hub.do/10.1002/jbt.21921
}}
==NR1H3==
 
* {{medline-title
|title=Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-[[MADD]] locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066205
}}
==NR2C2==
 
* {{medline-title
|title=Minireview: Pathophysiological roles of the TR4 nuclear receptor: lessons learned from mice lacking TR4.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24702179
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042077
}}
==NR5A2==
 
* {{medline-title
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
}}
==NRARP==
 
* {{medline-title
|title=Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing [[NRARP]].
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30274778
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.09.045
}}
==NRL==
 
* {{medline-title
|title=Development of a cyclophosphamide stress test to predict resilience to aging in mice.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32613492
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00222-z
}}
==NRP1==
 
* {{medline-title
|title=Neuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged mice.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25659123
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319892
}}
==NRSN2==
 
* {{medline-title
|title=Down-Regulated [[NRSN2]] Promotes Cell Proliferation and Survival Through PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26055238
|full-text-url=https://sci-hub.do/10.1007/s10620-015-3736-3
}}
==NRXN2==
 
* {{medline-title
|title=Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.
|date=01.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28013231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654756
}}
==NSF==
 
* {{medline-title
|title=Effects of air pollution on children from a socioecological perspective.
|date=15.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31727016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857293
}}
==NSMCE2==
 
* {{medline-title
|title=[[NSMCE2]] suppresses cancer and aging in mice independently of its SUMO ligase activity.
|date=03.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26443207
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641528
}}
==NSUN2==
 
* {{medline-title
|title=RNA methyltransferase [[NSUN2]] promotes stress-induced HUVEC senescence.
|date=12.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26992231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991368
}}
==NSUN5==
 
* {{medline-title
|title=Methylation of ribosomal RNA by [[NSUN5]] is a conserved mechanism modulating organismal lifespan.
|date=30.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25635753
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317494
}}
==NT5E==
 
* {{medline-title
|title=The [[NT5E]] gene variant strongly affects the degradation rate of inosine 5'-monophosphate under postmortem conditions in Japanese Black beef.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31401370
|full-text-url=https://sci-hub.do/10.1016/j.meatsci.2019.107893
}}
==NTHL1==
 
* {{medline-title
|title=Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205949
}}
==NTM==
 
* {{medline-title
|title=Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections.
|date=01.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27694475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504405
}}
==NTN4==
 
* {{medline-title
|title=[[EGF]]/[[EGF]]R upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence.
|date=04.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426
}}
==NTRK2==
 
* {{medline-title
|title=The Role of [[BDNF]] in Age-Dependent Changes of Excitatory and Inhibitory Synaptic Markers in the Human Prefrontal Cortex.
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27417517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101556
}}
==NUBP2==
 
* {{medline-title
|title=Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329260
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013013
}}
==NUCB2==
 
* {{medline-title
|title=Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise Killifish.
|date=31.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31906085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019235
}}
==NUPR1==
 
* {{medline-title
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327
}}
==NVL==
 
* {{medline-title
|title=[The effectiveness of non-invasive lung ventilation in lateral amyotrophic sclerosis].
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25345635
 
}}
==OCLN==
 
* {{medline-title
|title=Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats.
|date=17.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242723
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b02567
}}
==OCRL==
 
* {{medline-title
|title=Decreased urinary excretion of the ectodomain form of megalin (A-megalin) in children with [[OCRL]] gene mutations.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27766457
|full-text-url=https://sci-hub.do/10.1007/s00467-016-3535-x
}}
==OGFOD1==
 
* {{medline-title
|title=2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26118662
|full-text-url=https://sci-hub.do/10.1007/s00018-015-1978-z
}}
==OGN==
 
* {{medline-title
|title=Muscle and bone, two interconnected tissues.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25804855
|full-text-url=https://sci-hub.do/10.1016/j.arr.2015.03.002
}}
==OLFML3==
 
* {{medline-title
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
}}
==OMA1==
 
* {{medline-title
|title='Mitotherapy' for Heart Failure.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26965961
|full-text-url=https://sci-hub.do/10.1016/j.molmed.2016.02.007
}}
==OMD==
 
* {{medline-title
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|date=06.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
}}
==OOEP==
 
* {{medline-title
|title=Maternal gene [i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes.
|date=18.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085769
}}
==OPTN==
 
* {{medline-title
|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.
|date=24.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225
}}
==OR2AG1==
 
* {{medline-title
|title=The activation of [[OR51E1]] causes growth suppression of human prostate cancer cells.
|date=26.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27374083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217014
}}
==OR51E1==
 
* {{medline-title
|title=The activation of [[OR51E1]] causes growth suppression of human prostate cancer cells.
|date=26.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27374083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217014
}}
==OR51E2==
 
* {{medline-title
|title=The activation of [[OR51E1]] causes growth suppression of human prostate cancer cells.
|date=26.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27374083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217014
}}
==ORAI1==
 
* {{medline-title
|title=Calcium Dynamics of Ex Vivo Long-Term Cultured CD8  T Cells Are Regulated by Changes in Redox Metabolism.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27526200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985122
}}
==ORC2==
 
* {{medline-title
|title=mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25796566
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2015.03.014
}}
==OSCAR==
 
* {{medline-title
|title=Awareness tool for safe and responsible driving ([[OSC[[AR]]]]): a potential educational intervention for increasing interest, openness and knowledge about the abilities required and compensatory strategies among older drivers.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25802971
|full-text-url=https://sci-hub.do/10.1080/15389588.2014.994742
}}
==OSGEP==
 
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|date=11.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
}}
==P2RY10==
 
* {{medline-title
|title=Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury.
|date=12.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189983
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561964
}}
==P4HA2==
 
* {{medline-title
|title=Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients.
|date=03.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31560770
|full-text-url=https://sci-hub.do/10.1167/iovs.19-27921
}}
==P4HA3==
 
* {{medline-title
|title=Age-associated genes in human mammary gland drive human breast cancer progression.
|date=15.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32539762
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294649
}}
==PABPC1==
 
* {{medline-title
|title=Comprehensive Analysis of Interaction Networks of Telomerase Reverse Transcriptase with Multiple Bioinformatic Approaches: Deep Mining the Potential Functions of Telomere and Telomerase.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28281877
|full-text-url=https://sci-hub.do/10.1089/rej.2016.1909
}}
==PACSIN1==
 
* {{medline-title
|title=GluN3A promotes dendritic spine pruning and destabilization during postnatal development.
|date=09.07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25009255
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608362
}}
==PAFAH2==
 
* {{medline-title
|title=Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30521374
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404557
}}
==PAK2==
 
* {{medline-title
|title=Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts.
|date=11-12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26794818
|full-text-url=https://sci-hub.do/10.7417/T.2015.1902
}}
==PALB2==
 
* {{medline-title
|title=A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407996
|full-text-url=https://sci-hub.do/10.1016/j.jval.2017.01.006
}}
==PALM==
 
* {{medline-title
|title=Signatures of malaria vaccine efficacy in ageing murine immune memory.
|date=05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24495208
|full-text-url=https://sci-hub.do/10.1111/pim.12104
}}
==PAPSS1==
 
* {{medline-title
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
==PARG==
 
* {{medline-title
|title=[Genotype and allele frequencies of U[[CP]] and PP[[AR]] gene families in residents of besieged Leningrad and in the control group].
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826986
 
}}
==PARP2==
 
* {{medline-title
|title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417
}}
==PATE1==
 
* {{medline-title
|title=Aged men share the sperm protein [[PATE1]] defect with young asthenozoospermia patients.
|date=04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25637620
|full-text-url=https://sci-hub.do/10.1093/humrep/dev003
}}
==PAX1==
 
* {{medline-title
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|date=26.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
}}
==PAX4==
 
* {{medline-title
|title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685
|full-text-url=https://sci-hub.do/10.1134/S0006297915030062
}}
==PAX7==
 
* {{medline-title
|title=Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30006671
|full-text-url=https://sci-hub.do/10.1007/s00421-018-3943-7
}}
==PAX8==
 
* {{medline-title
|title=Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging.
|date=13.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31518338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781991
}}
==PCBP2==
 
* {{medline-title
|title=RNA-binding Protein [[PCBP2]] Regulates p73 Expression and p73-dependent Antioxidant Defense.
|date=29.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26907686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850300
}}
==PCCA==
 
* {{medline-title
|title=Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29159707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832583
}}
==PCCB==
 
* {{medline-title
|title=Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29159707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832583
}}
==PCDH9==
 
* {{medline-title
|title=A reverse genetics cell-based evaluation of genes linked to healthy human tissue age.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27698205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161526
}}
==PCDHGA3==
 
* {{medline-title
|title=DNA methylation associated with healthy aging of elderly twins.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30136078
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294724
}}
==PCK1==
 
* {{medline-title
|title=[[PCK1]] is negatively regulated by bta-miR-26a, and a single-nucleotide polymorphism in the 3' untranslated region is involved in semen quality and longevity of Holstein bulls.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26725319
|full-text-url=https://sci-hub.do/10.1002/mrd.22613
}}
==PCMTD1==
 
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
==PCP4==
 
* {{medline-title
|title=Specific age-related molecular alterations in the cerebellum of Down syndrome mouse models.
|date=01.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27297494
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2016.06.003
}}
==PDE2A==
 
* {{medline-title
|title=TAK-915, a phosphodiesterase 2A inhibitor, ameliorates the cognitive impairment associated with aging in rodent models.
|date=30.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521738
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2019.112192
}}
==PDE3A==
 
* {{medline-title
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490
|full-text-url=https://sci-hub.do/10.1071/RD14472
}}
==PDE5A==
 
* {{medline-title
|title=Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass.
|date=23.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32513693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321982
}}
==PDE9A==
 
* {{medline-title
|title=Identification of new [[PDE9A]] isoforms and how their expression and subcellular compartmentalization in the brain change across the life span.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29505961
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871571
}}
==PDGFRA==
 
* {{medline-title
|title=GBM-associated mutations and altered protein expression are more common in young patients.
|date=25.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491
}}
==PDHB==
 
* {{medline-title
|title=Neuron-specific knockdown of Drosophila [[PDHB]] induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting.
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501567
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.02.035
}}
==PDP1==
 
* {{medline-title
|title=Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training.
|date=01.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27221120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967149
}}
==PDP2==
 
* {{medline-title
|title=Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training.
|date=01.07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27221120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967149
}}
==PEBP1==
 
* {{medline-title
|title=[i]Drosophila[/i] [[PEBP1]] inhibits intestinal stem cell aging via suppression of ERK pathway.
|date=06.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719584
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915051
}}
==PER3==
 
* {{medline-title
|title=Effects of [[PER3]] clock gene polymorphisms on aging-related changes of the cerebral cortex.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28900721
|full-text-url=https://sci-hub.do/10.1007/s00429-017-1513-0
}}
==PEX1==
 
* {{medline-title
|title=Transcription factor [[PEX1]] modulates extracellular matrix turnover through regulation of MMP-9 expression.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27826738
|full-text-url=https://sci-hub.do/10.1007/s00441-016-2527-2
}}
==PEX19==
 
* {{medline-title
|title=A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells.
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31854076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996960
}}
==PEX5==
 
* {{medline-title
|title=Aging lowers [[PEX5]] levels in cortical neurons in male and female mouse brains.
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32777345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484460
}}
==PF4V1==
 
* {{medline-title
|title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x
}}
==PFKL==
 
* {{medline-title
|title=Developmental changes in hepatic glucose metabolism in a newborn piglet model: A comparative analysis for suckling period and early weaning period.
|date=19.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802463
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.01.114
}}
==PGAM1==
 
* {{medline-title
|title=The aged testis. A good model to find proteins involved in age-related changes of testis by proteomic analysis.
|date=01-02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24597284
 
}}
==PGAP1==
 
* {{medline-title
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
}}
==PGK2==
 
* {{medline-title
|title=Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31472347
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2019.124650
}}
==PGLS==
 
* {{medline-title
|title=547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates.
|date=28.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883628
}}
==PGLYRP1==
 
* {{medline-title
|title=PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan.
|date=16.01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24439372
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928474
}}
==PGM1==
 
* {{medline-title
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle.
|date=15.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004
}}
==PHF19==
 
* {{medline-title
|title=A reverse genetics cell-based evaluation of genes linked to healthy human tissue age.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27698205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161526
}}
==PHF6==
 
* {{medline-title
|title=miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6.
|date=03.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25556700
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337614
}}
==PHGDH==
 
* {{medline-title
|title=Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase.
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31108107
|full-text-url=https://sci-hub.do/10.1016/j.taap.2019.05.014
}}
==PHLPP1==
 
* {{medline-title
|title=Defects in the [[CAPN1]] Gene Result in Alterations in Cerebellar Development and Cerebellar Ataxia in Mice and Humans.
|date=28.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27320912
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927383
}}
==PHOSPHO1==
 
* {{medline-title
|title=Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26232374
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652607
}}
==PI4KA==
 
* {{medline-title
|title=Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26001726
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2015.05.019
}}
==PICK1==
 
* {{medline-title
|title=Development- and age-related alterations in the expression of AMPA receptor subunit GluR2 and its trafficking proteins in the hippocampus of male mouse brain.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25559403
|full-text-url=https://sci-hub.do/10.1007/s10522-014-9548-6
}}
==PIGR==
 
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
==PIK3C2A==
 
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
==PIK3C3==
 
* {{medline-title
|title=Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo.
|date=03.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26098646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615103
}}
==PIK3CB==
 
* {{medline-title
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
==PIK3R1==
 
* {{medline-title
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
}}
==PIK3R3==
 
* {{medline-title
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
==PIM1==
 
* {{medline-title
|title=[[PIM1]]-catalyzed [[CBX8]] phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast.
|date=27.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29763603
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.05.070
}}
==PIP5K1C==
 
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
}}
==PIPOX==
 
* {{medline-title
|title=Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma.
|date=21.12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28058013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175245
}}
==PIR==
 
* {{medline-title
|title=Proteomic analysis of changes in mitochondrial protein expression during peach fruit ripening and senescence.
|date=16.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27288903
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2016.06.005
}}
==PKD1==
 
* {{medline-title
|title=The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response.
|date=16.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29420297
|full-text-url=https://sci-hub.do/10.1242/jcs.207217
}}
==PKHD1L1==
 
* {{medline-title
|title=[Role of [[PLAT]], [[PKHD1L1]], [[STK38L]] and [[TEAD1]] genes Alu-polymorphism for longevity].
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28556638
 
}}
==PKLR==
 
* {{medline-title
|title=Developmental changes in hepatic glucose metabolism in a newborn piglet model: A comparative analysis for suckling period and early weaning period.
|date=19.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802463
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.01.114
}}
==PKP2==
 
* {{medline-title
|title=Molecular disturbance underlies to arrhythmogenic cardiomyopathy induced by transgene content, age and exercise in a truncated [[PKP2]] mouse model.
|date=01.09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27412010
|full-text-url=https://sci-hub.do/10.1093/hmg/ddw213
}}
==PLA2G4A==
 
* {{medline-title
|title=Coordination of gene expression of arachidonic and docosahexaenoic acid cascade enzymes during human brain development and aging.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24963629
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070994
}}
==PLAGL1==
 
* {{medline-title
|title=Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824446
|full-text-url=https://sci-hub.do/10.1136/bjsports-2014-094073
}}
==PLAT==
 
* {{medline-title
|title=[Role of [[PLAT]], [[PKHD1L1]], [[STK38L]] and [[TEAD1]] genes Alu-polymorphism for longevity].
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28556638
 
}}
==PLCB1==
 
* {{medline-title
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
==PLCD1==
 
* {{medline-title
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
==PLCG2==
 
* {{medline-title
|title=A nonsynonymous mutation in [[PLCG2]] reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31131421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501
}}
==PLEC==
 
* {{medline-title
|title=Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24496748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209016
}}
==PLEKHO1==
 
* {{medline-title
|title=Increased [[PLEKHO1]] within osteoblasts suppresses Smad-dependent BMP signaling to inhibit bone formation during aging.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28083909
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334543
}}
==PLIN1==
 
* {{medline-title
|title=Determination of the Mechanisms that Cause Sarcopenia through cDNA Microarray.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28555711
|full-text-url=https://sci-hub.do/10.14283/jfa.2017.13
}}
==PLK1==
 
* {{medline-title
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
}}
==PLK2==
 
* {{medline-title
|title=Age- and brain region-dependent α-synuclein oligomerization is attributed to alterations in intrinsic enzymes regulating α-synuclein phosphorylation in aging monkey brains.
|date=23.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27032368
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890980
}}
==PLXNA4==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==PMM2==
 
* {{medline-title
|title=Synaptic roles for phosphomannomutase type 2 in a new Drosophila congenital disorder of glycosylation disease model.
|date=01.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26940433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892659
}}
==PMP22==
 
* {{medline-title
|title=Role of microRNAs in senescence and its contribution to peripheral neuropathy in the arsenic exposed population of West Bengal, India.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29107899
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2017.09.063
}}
==PMS1==
 
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
==PMS2==
 
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
==PNPLA6==
 
* {{medline-title
|title=Delayed Induction of Human NTE ([[PNPLA6]]) Rescues Neurodegeneration and Mobility Defects of Drosophila swiss cheese (sws) Mutants.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26671664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684404
}}
==PODXL==
 
* {{medline-title
|title=Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts.
|date=01.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635509
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576272
}}
==POLDIP2==
 
* {{medline-title
|title=Essential role of [[POLDIP2]] in Tau aggregation and neurotoxicity via autophagy/proteasome inhibition.
|date=26.06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25930997
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.04.084
}}
==POLL==
 
* {{medline-title
|title=Temporal trends in loss of life expectancy after a cancer diagnosis among the Australian population.
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32062407
|full-text-url=https://sci-hub.do/10.1016/j.canep.2020.101686
}}
==POLN==
 
* {{medline-title
|title=Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28570559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472330
}}
==POLR3A==
 
* {{medline-title
|title=Nucleolar disruption, activation of P53 and premature senescence in [[POLR3A]]-mutated Wiedemann-Rautenstrauch syndrome fibroblasts.
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32976914
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111360
}}
==POU2F1==
 
* {{medline-title
|title=Methyl CpG level at distal part of heat-shock protein promoter HSP70 exhibits epigenetic memory for heat stress by modulating recruitment of [[POU2F1]]-associated nucleosome-remodeling deacetylase (NuRD) complex.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28278364
|full-text-url=https://sci-hub.do/10.1111/jnc.14014
}}
==POU3F2==
 
* {{medline-title
|title=[[POU3F2]] participates in cognitive function and adult hippocampal neurogenesis via mammalian-characteristic amino acid repeats.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782255
|full-text-url=https://sci-hub.do/10.1111/gbb.12408
}}
==POU4F3==
 
* {{medline-title
|title=In Vivo Interplay between p27 , [[GATA3]], [[ATOH1]], and [[POU4F3]] Converts Non-sensory Cells to Hair Cells in Adult Mice.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28402854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423718
}}
==PPA2==
 
* {{medline-title
|title=Characterization of long living yeast deletion mutants that lack mitochondrial metabolism genes DSS1, [[PPA2]] and AFG3.
|date=20.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31082499
|full-text-url=https://sci-hub.do/10.1016/j.gene.2019.05.001
}}
==PPARA==
 
* {{medline-title
|title=[Genotype and allele frequencies of U[[CP]] and PP[[AR]] gene families in residents of besieged Leningrad and in the control group].
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826986
 
}}
==PPFIA1==
 
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
==PPM1A==
 
* {{medline-title
|title=The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1.
|date=03.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31382626
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723262
}}
==PPM1B==
 
* {{medline-title
|title=[[PPM1B]] depletion induces premature senescence in human IMR-90 fibroblasts.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24674756
|full-text-url=https://sci-hub.do/10.1016/j.mad.2014.03.003
}}
==PPP1R12B==
 
* {{medline-title
|title=BDA-410 Treatment Reduces Body Weight and Fat Content by Enhancing Lipolysis in Sedentary Senescent Mice.
|date=01.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27789616
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861946
}}
==PPP1R3C==
 
* {{medline-title
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
}}
==PPP2R1A==
 
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
==PPP2R2B==
 
* {{medline-title
|title=Germline genetics of the p53 pathway affect longevity in a gender specific manner.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24654968
|full-text-url=https://sci-hub.do/10.2174/1874609807666140321150751
}}
==PPP2R3C==
 
* {{medline-title
|title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667
}}
==PPP3CB==
 
* {{medline-title
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
}}
==PRDM1==
 
* {{medline-title
|title=Age-related changes in the [[BACH2]] and [[PRDM1]] genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.
|date=17.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337793
}}
==PRDM8==
 
* {{medline-title
|title=[[PRDM8]] reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation.
|date=20.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32819411
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439574
}}
==PRG2==
 
* {{medline-title
|title=Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439450
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391678
}}
==PRG4==
 
* {{medline-title
|title=Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis.
|date=08.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415892
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821202
}}
==PRKAA1==
 
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
==PRKAA2==
 
* {{medline-title
|title=Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24760536
|full-text-url=https://sci-hub.do/10.1530/EJE-14-0006
}}
==PRKCB==
 
* {{medline-title
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
}}
==PRKCD==
 
* {{medline-title
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827
}}
==PRKCH==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==PRKDC==
 
* {{medline-title
|title=DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis.
|date=29.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31464599
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716822
}}
==PRKN==
 
* {{medline-title
|title=[[PRKN]]-regulated mitophagy and cellular senescence during COPD pathogenesis.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30290714
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351145
}}
==PRLR==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==PRM1==
 
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
}}
==PRM2==
 
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
}}
==PRODH==
 
* {{medline-title
|title=Proline dehydrogenase promotes senescence through the generation of reactive oxygen species.
|date=15.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28264926
|full-text-url=https://sci-hub.do/10.1242/jcs.196469
}}
==PROX1==
 
* {{medline-title
|title=Molecular control of two novel migratory paths for CGE-derived interneurons in the developing mouse brain.
|date=15.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27034423
|full-text-url=https://sci-hub.do/10.1242/dev.131102
}}
==PRR9==
 
* {{medline-title
|title=Circadian control of [i]ORE1[/i] by [[PRR9]] positively regulates leaf senescence in [i]Arabidopsis[/i].
|date=14.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30065116
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099856
}}
==PRRX1==
 
* {{medline-title
|title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862
}}
==PRSS16==
 
* {{medline-title
|title=The complex genetics of gait speed: genome-wide meta-analysis approach.
|date=10.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28077804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310665
}}
==PSAP==
 
* {{medline-title
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
}}
==PSMA7==
 
* {{medline-title
|title=Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407635
|full-text-url=https://sci-hub.do/10.1159/000468944
}}
==PSMB10==
 
* {{medline-title
|title=Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28233611
|full-text-url=https://sci-hub.do/10.1016/j.kint.2016.12.018
}}
==PSMB5==
 
* {{medline-title
|title=Ameliorating replicative senescence of human bone marrow stromal cells by [[PSMB5]] overexpression.
|date=24.01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24393841
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2013.12.113
}}
==PSMB8==
 
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
}}
==PSMB9==
 
* {{medline-title
|title=Identification of the activating cytotoxicity receptor NKG2D as a senescence marker in zero-hour kidney biopsies is indicative for clinical outcome.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28233611
|full-text-url=https://sci-hub.do/10.1016/j.kint.2016.12.018
}}
==PSMD11==
 
* {{medline-title
|title=The effect and mechanism of 19S proteasome [[PSMD11]]/Rpn6 subunit in D-Galactose induced mimetic aging models.
|date=01.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32450067
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.112093
}}
==PSMD13==
 
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
==PSMD14==
 
* {{medline-title
|title=Upregulation of deubiquitinase [[PSMD14]] in lung adenocarcinoma (LUAD) and its prognostic significance.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32226511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086243
}}
==PSMG1==
 
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
}}
==PTCH1==
 
* {{medline-title
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
}}
==PTER==
 
* {{medline-title
|title=[[TH]]E EFFECTS OF XAN[[TH]]O[[TOX]]IN ON [[TH]]E BIOLOGY AND BIOCHEMISTRY OF Galleria mellonella L. ([[LEP]]IDO[[PTER]]A: PYRALIDAE).
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25821173
|full-text-url=https://sci-hub.do/10.1002/arch.21236
}}
==PTGDR==
 
* {{medline-title
|title=Does prostaglandin D2 hold the cure to male pattern baldness?
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24521203
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982925
}}
==PTGDS==
 
* {{medline-title
|title=Does prostaglandin D2 hold the cure to male pattern baldness?
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24521203
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982925
}}
==PTGER2==
 
* {{medline-title
|title=Molecular cloning and expression analysis of prostaglandin E receptor 2 gene in cashmere goat (Capra hircus) skin during hair follicle development.
|date=03.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24555795
|full-text-url=https://sci-hub.do/10.1080/10495398.2013.826236
}}
==PTH2R==
 
* {{medline-title
|title=Variation in the [[[[PTH]]2R]] gene is associated with age-related degenerative changes in the lumbar spine.
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24378925
|full-text-url=https://sci-hub.do/10.1007/s00774-013-0550-x
}}
==PTHLH==
 
* {{medline-title
|title=Variation in the [[[[PTH]]2R]] gene is associated with age-related degenerative changes in the lumbar spine.
|date=01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24378925
|full-text-url=https://sci-hub.do/10.1007/s00774-013-0550-x
}}
==PTK2==
 
* {{medline-title
|title=[[PTK2]] rs7460 and rs7843014 polymorphisms and exceptional longevity: a functional replication study.
|date=10.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24930376
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203112
}}
==PTK7==
 
* {{medline-title
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|date=05.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
}}
==PTP4A3==
 
* {{medline-title
|title=Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease.
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32402127
|full-text-url=https://sci-hub.do/10.1002/adbi.202000044
}}
==PTPN1==
 
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
==PTPN7==
 
* {{medline-title
|title=DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28419903
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.04.006
}}
==PTPRC==
 
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
==PTPRD==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==PTPRR==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==PTPRT==
 
* {{medline-title
|title=The complex genetics of gait speed: genome-wide meta-analysis approach.
|date=10.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28077804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310665
}}
==PTTG1==
 
* {{medline-title
|title=[Down-regulated [[PTTG1]] expression promotes the senescence of human prostate cancer LNCaP-AI].
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32216239
 
}}
==PUM1==
 
* {{medline-title
|title=Identification of reference genes for RT-qPCR data normalisation in aging studies.
|date=27.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764958
}}
==PXN==
 
* {{medline-title
|title=pxn-1 and pxn-2 May Interact Negatively during Neuronal Development and Aging in C. elegans.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26194821
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546945
}}
==QRFPR==
 
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
==RAB1B==
 
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
==RAC3==
 
* {{medline-title
|title=[[RAC3]] more than a nuclear receptor coactivator: a key inhibitor of senescence that is downregulated in aging.
|date=15.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26469953
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632280
}}
==RAD21==
 
* {{medline-title
|title=Suppression of [[RAD21]] Induces Senescence of MDA-[[MB]]-231 Human Breast Cancer Cells Through [[RB1]] Pathway Activation Via c-Myc Downregulation.
|date=06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26529363
|full-text-url=https://sci-hub.do/10.1002/jcb.25426
}}
==RAD23A==
 
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
==RAD51B==
 
* {{medline-title
|title=Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human [[RAD52]] gene in a cardiovascular cohort.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024686
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.10.003
}}
==RAD51C==
 
* {{medline-title
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
}}
==RAD9A==
 
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
==RAI1==
 
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
==RAMP1==
 
* {{medline-title
|title=Depressed perivascular sensory innervation of mouse mesenteric arteries with advanced age.
|date=15.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26010764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933107
}}
==RAPGEF2==
 
* {{medline-title
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
}}
==RARB==
 
* {{medline-title
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896
}}
==RASEF==
 
* {{medline-title
|title=Near-genomewide RNAi screening for regulators of [[BRAF]](V600E) -induced senescence identifies [[RASEF]], a gene epigenetically silenced in melanoma.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24703243
|full-text-url=https://sci-hub.do/10.1111/pcmr.12248
}}
==RASGEF1A==
 
* {{medline-title
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
==RASGRF2==
 
* {{medline-title
|title=A single nucleotide polymorphism associated with reduced alcohol intake in the [[RASGRF2]] gene predicts larger cortical volumes but faster longitudinal ventricular expansion in the elderly.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24409144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867747
}}
==RASGRP1==
 
* {{medline-title
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
}}
==RB1CC1==
 
* {{medline-title
|title=Tumor-suppressive functions of 15-Lipoxygenase-2 and [[RB1CC1]] in prostate cancer.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24732589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111726
}}
==RBBP4==
 
* {{medline-title
|title=Retinoblastoma-binding Protein 4-regulated Classical Nuclear Transport Is Involved in Cellular Senescence.
|date=04.12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26491019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705941
}}
==RBL1==
 
* {{medline-title
|title=Deregulation of hsa-miR-20b expression in [[TNF]]-α-induced premature senescence of human pulmonary microvascular endothelial cells.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28595801
|full-text-url=https://sci-hub.do/10.1016/j.mvr.2017.06.002
}}
==RBM25==
 
* {{medline-title
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif.
|date=29.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004
}}
==RBM3==
 
* {{medline-title
|title=Infants Uniquely Express High Levels of [[RBM3]] and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399610
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311128
}}
==RBM38==
 
* {{medline-title
|title=Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating [[PTEN]].
|date=15.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29330147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340497
}}
==RBM6==
 
* {{medline-title
|title=Bayesian association scan reveals loci associated with human lifespan and linked biomarkers.
|date=27.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28748955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537485
}}
==RBMXL1==
 
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
==RBP1==
 
* {{medline-title
|title=The SR proteins SF2 and [[RBP1]] regulate triglyceride storage in the fat body of Drosophila.
|date=27.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277943
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.151
}}
==RCC1==
 
* {{medline-title
|title=X[[RCC1]] and XPD genetic polymorphisms and susceptibility to age-related cataract: a meta-analysis.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384174
}}
==RCC2==
 
* {{medline-title
|title=X[[RCC1]] and XPD genetic polymorphisms and susceptibility to age-related cataract: a meta-analysis.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384174
}}
==REL==
 
* {{medline-title
|title=Impact of loss of NF-κB1, NF-κB2 or c-[[REL]] on SLE-like autoimmune disease and lymphadenopathy in Fas(lpr/lpr) mutant mice.
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26084385
|full-text-url=https://sci-hub.do/10.1038/icb.2015.66
}}
==RELB==
 
* {{medline-title
|title=New control of the senescence barrier in breast cancer.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158912
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051141
}}
==REV1==
 
* {{medline-title
|title=[[REV1]] inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks.
|date=17.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168727
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682577
}}
==RGL1==
 
* {{medline-title
|title=Arabidopsis WRKY45 Interacts with the DELLA Protein [[RGL1]] to Positively Regulate Age-Triggered Leaf Senescence.
|date=12.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28735023
|full-text-url=https://sci-hub.do/10.1016/j.molp.2017.07.008
}}
==RGS1==
 
* {{medline-title
|title=Age-related changes in regulator of G-protein signaling (RGS)-10 expression in peripheral and central immune cells may influence the risk for age-related degeneration.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25784210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417042
}}
==RGS10==
 
* {{medline-title
|title=Age-related changes in regulator of G-protein signaling (RGS)-10 expression in peripheral and central immune cells may influence the risk for age-related degeneration.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25784210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417042
}}
==RGS14==
 
* {{medline-title
|title=Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29654651
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052469
}}
==RGS3==
 
* {{medline-title
|title=The roles of ribosomal protein S19 C-terminus in a shortened neutrophil lifespan through delta lactoferrin.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26003841
|full-text-url=https://sci-hub.do/10.1016/j.imbio.2015.05.006
}}
==RHCG==
 
* {{medline-title
|title=Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.
|date=06.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170090
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594797
}}
==RHEBL1==
 
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
}}
==RHOB==
 
* {{medline-title
|title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes.
|date=13.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600
}}
==RIC3==
 
* {{medline-title
|title=Genetic modifiers of cognitive maintenance among older adults.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24616004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107001
}}
==RIF1==
 
* {{medline-title
|title=53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
|date=02.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653568
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993210
}}
==RIMS2==
 
* {{medline-title
|title=Age-related gene and miRNA expression changes in airways of healthy individuals.
|date=06.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842487
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403379
}}
==RIN3==
 
* {{medline-title
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828
}}
==RNASEL==
 
* {{medline-title
|title=Age-related methylation profiles of equine blood leukocytes in the [[RNASEL]] locus.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26553552
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963465
}}
==RNF10==
 
* {{medline-title
|title=Reduced RING finger protein 10 expression in macrophages is associated with aging-related inflammation.
|date=28.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33249776
|full-text-url=https://sci-hub.do/10.1002/2211-5463.13049
}}
==RNF111==
 
* {{medline-title
|title=Global-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo Modifiers.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27200078
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848295
}}
==RNF13==
 
* {{medline-title
|title=The effects of environmental stressors on candidate aging associated genes.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32344118
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110952
}}
==RNF144A==
 
* {{medline-title
|title=Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31280115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732230
}}
==RNF168==
 
* {{medline-title
|title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001
}}
==RORB==
 
* {{medline-title
|title=Effects of circadian clock genes and environmental factors on cognitive aging in old adults in a Taiwanese population.
|date=11.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421829
}}
==ROS1==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==RP1==
 
* {{medline-title
|title=Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats.
|date=20.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248655
}}
==RPA2==
 
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
==RPL10==
 
* {{medline-title
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
==RPL13==
 
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
==RPL18==
 
* {{medline-title
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
==RPL3==
 
* {{medline-title
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
==RPL30==
 
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
==RPL31==
 
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
==RPL35==
 
* {{medline-title
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
==RPL36==
 
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
==RPL37==
 
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
==RPL4==
 
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
==RPS11==
 
* {{medline-title
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
==RPS19BP1==
 
* {{medline-title
|title=Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659678
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2020.153275
}}
==RPS2==
 
* {{medline-title
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
==RPS20==
 
* {{medline-title
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
==RPS4X==
 
* {{medline-title
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
==RPS6KA1==
 
* {{medline-title
|title=Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366598
}}
==RPS6KB1==
 
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
==RPS7==
 
* {{medline-title
|title=Comprehensive analysis of the ubiquitinome during oncogene-induced senescence in human fibroblasts.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25785348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614229
}}
==RRAD==
 
* {{medline-title
|title=Pan-senescence transcriptome analysis identified [[RRAD]] as a marker and negative regulator of cellular senescence.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391675
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.10.457
}}
==RRM2==
 
* {{medline-title
|title=Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of [[ATR]] mutant mice.
|date=01.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25838540
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387711
}}
==RRM2B==
 
* {{medline-title
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179
}}
==RS1==
 
* {{medline-title
|title=Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h-/- mouse.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24694538
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047144
}}
==RSAD2==
 
* {{medline-title
|title=Progression of pathology in [[PINK1]]-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation.
|date=02.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28768533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541666
}}
==RSF1==
 
* {{medline-title
|title=The SR proteins SF2 and [[RBP1]] regulate triglyceride storage in the fat body of Drosophila.
|date=27.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277943
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.151
}}
==RSL1D1==
 
* {{medline-title
|title=Ribosomal L1 domain and lysine-rich region are essential for CSIG/ [[RSL1D1]] to regulate proliferation and senescence.
|date=15.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26686419
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.12.004
}}
==RTN3==
 
* {{medline-title
|title=Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
|date=09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26619807
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887420
}}
==RTN4==
 
* {{medline-title
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
}}
==RUNX3==
 
* {{medline-title
|title=circLARP4 induces cellular senescence through regulating miR-761/[[RUNX3]]/p53/p21 signaling in hepatocellular carcinoma.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30520539
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361555
}}
==RUVBL2==
 
* {{medline-title
|title=Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue.
|date=09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26253138
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577010
}}
==RXFP1==
 
* {{medline-title
|title=Sex- and age-specific differences in relaxin family peptide receptor expression within the hippocampus and amygdala in rats.
|date=22.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25313002
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2014.10.006
}}
==RXFP3==
 
* {{medline-title
|title=The [[RXFP3]] receptor is functionally associated with cellular responses to oxidative stress and DNA damage.
|date=03.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794429
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932917
}}
==RXRA==
 
* {{medline-title
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923
}}
==RXRG==
 
* {{medline-title
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
}}
==RYR3==
 
* {{medline-title
|title=Association of the [[RYR3]] gene polymorphisms with atherosclerosis in elderly Japanese population.
|date=14.01.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24423397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898238
}}
==S100A13==
 
* {{medline-title
|title=[[S100A13]] promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α.
|date=23.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30670674
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366962
}}
==S100A6==
 
* {{medline-title
|title=Sex differences in distribution of cannabinoid receptors (CB1 and CB2), [[S100A6]] and CacyBP/SIP in human ageing hearts.
|date=27.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30482253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258148
}}
==S100A7==
 
* {{medline-title
|title=The secreted protein [[S100A7]] (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulators.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25621169
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304136
}}
==S100P==
 
* {{medline-title
|title=Cancer-associated [[S100P]] protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance.
|date=19.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26967060
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008377
}}
==SAA2==
 
* {{medline-title
|title=Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884545
}}
==SACM1L==
 
* {{medline-title
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567
}}
==SAMD10==
 
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
==SAMD12==
 
* {{medline-title
|title=Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882010
}}
==SAMHD1==
 
* {{medline-title
|title=Gut microbiota lipopolysaccharide accelerates inflamm-aging in mice.
|date=16.01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26772806
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715324
}}
==SARM1==
 
* {{medline-title
|title=Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.
|date=03.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640801
}}
==SAT1==
 
* {{medline-title
|title=Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544364
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469548
}}
==SCAMP1==
 
* {{medline-title
|title=Secretory Carrier Membrane Protein (SCAMP) deficiency influences behavior of adult flies.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25478561
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235465
}}
==SCAMP4==
 
* {{medline-title
|title=[[SCAMP4]] enhances the senescent cell secretome.
|date=01.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967290
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075036
}}
==SCD5==
 
* {{medline-title
|title=Bovine brain region-specific stearoyl-CoA desaturase expression and fatty acid composition.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25899038
|full-text-url=https://sci-hub.do/10.1007/s11745-015-4015-y
}}
==SCGB1A1==
 
* {{medline-title
|title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685
|full-text-url=https://sci-hub.do/10.1134/S0006297915030062
}}
==SCGB2A2==
 
* {{medline-title
|title=Sensitivity of neoplastic cells to senescence unveiled under standard cell culture conditions.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25964555
 
}}
==SCGB3A2==
 
* {{medline-title
|title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685
|full-text-url=https://sci-hub.do/10.1134/S0006297915030062
}}
==SCN2A==
 
* {{medline-title
|title=Na 1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age.
|date=09.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31501495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733925
}}
==SCN9A==
 
* {{medline-title
|title=The [[SCN9A]] channel and plasma membrane depolarization promote cellular senescence through Rb pathway.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29446526
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946064
}}
==SCNN1B==
 
* {{medline-title
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects.
|date=18.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
}}
==SCO1==
 
* {{medline-title
|title=Real-Time PCR Analysis of Metabolism-Related Genes in a Long-Lived Model of C. elegans.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32219749
|full-text-url=https://sci-hub.do/10.1007/978-1-0716-0471-7_12
}}
==SCO2==
 
* {{medline-title
|title=Role of SCOX in determination of Drosophila melanogaster lifespan.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25057436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106651
}}
==SCRIB==
 
* {{medline-title
|title=Scribble is required for pregnancy-induced alveologenesis in the adult mammary gland.
|date=15.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27179074
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920253
}}
==SCX==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==SDC2==
 
* {{medline-title
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
}}
==SDC3==
 
* {{medline-title
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
}}
==SDHC==
 
* {{medline-title
|title=Endogenous reactive oxygen species cause astrocyte defects and neuronal dysfunctions in the hippocampus: a new model for aging brain.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27623715
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242301
}}
==SEC23A==
 
* {{medline-title
|title=Pancreatic [[SEC23B]] deficiency is sufficient to explain the perinatal lethality of germline [[SEC23B]] deficiency in mice.
|date=14.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27297878
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906273
}}
==SEC23B==
 
* {{medline-title
|title=Pancreatic [[SEC23B]] deficiency is sufficient to explain the perinatal lethality of germline [[SEC23B]] deficiency in mice.
|date=14.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27297878
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906273
}}
==SELENBP1==
 
* {{medline-title
|title=A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31557719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812014
}}
==SELENOH==
 
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
}}
==SELENOK==
 
* {{medline-title
|title=Dietary selenium deficiency and supplementation differentially modulate the expression of two ER-resident selenoproteins (selenoprotein K and selenoprotein M) in the ovaries of aged mice: Preliminary data.
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736983
|full-text-url=https://sci-hub.do/10.1016/j.repbio.2020.07.006
}}
==SELENOP==
 
* {{medline-title
|title=Analyses of Selenotranscriptomes and Selenium Concentrations in Response to Dietary Selenium Deficiency and Age Reveal Common and Distinct Patterns by Tissue and Sex in Telomere-Dysfunctional Mice.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28855418
|full-text-url=https://sci-hub.do/10.3945/jn.117.247775
}}
==SELENOT==
 
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
}}
==SELENOV==
 
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
}}
==SELENOW==
 
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
}}
==SELP==
 
* {{medline-title
|title=Effect of age on expression of spermatogonial markers in bovine testis and isolated cells.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27180120
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2016.04.004
}}
==SEMA3A==
 
* {{medline-title
|title=Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging.
|date=05.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661929
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2018.12.021
}}
==SEMA6C==
 
* {{medline-title
|title=Suppression of [[SEMA6C]] promotes preantral follicles atresia with decreased cell junctions in mice ovaries.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30256425
|full-text-url=https://sci-hub.do/10.1002/jcp.27294
}}
==SENP1==
 
* {{medline-title
|title=Aging-related SUMOylation pattern in the cortex and blood plasma of wild type mice.
|date=06.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325714
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.01.004
}}
==SENP6==
 
* {{medline-title
|title=Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32827359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576240
}}
==SERPINA1==
 
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
==SERPINB2==
 
* {{medline-title
|title=An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through [[SERPINB2]].
|date=03.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612665
}}
==SESN1==
 
* {{medline-title
|title=Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751091
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.006
}}
==SETX==
 
* {{medline-title
|title=Sen1, the homolog of human Senataxin, is critical for cell survival through regulation of redox homeostasis, mitochondrial function, and the TOR pathway in Saccharomyces cerevisiae.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27718307
|full-text-url=https://sci-hub.do/10.1111/febs.13917
}}
==SFPQ==
 
* {{medline-title
|title=Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis.
|date=08.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32267831
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185106
}}
==SFRP5==
 
* {{medline-title
|title=[[SFRP5]] serves a beneficial role in arterial aging by inhibiting the proliferation, migration and inflammation of smooth muscle cells.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30221661
|full-text-url=https://sci-hub.do/10.3892/mmr.2018.9467
}}
==SFTPA1==
 
* {{medline-title
|title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685
|full-text-url=https://sci-hub.do/10.1134/S0006297915030062
}}
==SGCE==
 
* {{medline-title
|title=Exercise-associated DNA methylation change in skeletal muscle and the importance of imprinted genes: a bioinformatics meta-analysis.
|date=12.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824446
|full-text-url=https://sci-hub.do/10.1136/bjsports-2014-094073
}}
==SGK1==
 
* {{medline-title
|title=Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells.
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223380
|full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.120.14642
}}
==SGSH==
 
* {{medline-title
|title=MPS-IIIA mice acquire autistic behaviours with age.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520737
|full-text-url=https://sci-hub.do/10.1007/s10545-018-0160-9
}}
==SH2B1==
 
* {{medline-title
|title=The Dyslexia-susceptibility Protein [[KIAA0319]] Inhibits Axon Growth Through Smad2 Signaling.
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28334068
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905272
}}
==SH2B3==
 
* {{medline-title
|title=Genome-wide meta-analysis associates HLA-DQA1/DRB1 and [[LPA]] and lifestyle factors with human longevity.
|date=13.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29030599
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715013
}}
==SHC1==
 
* {{medline-title
|title=Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence.
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802937
|full-text-url=https://sci-hub.do/10.1016/j.plefa.2015.10.006
}}
==SHD==
 
* {{medline-title
|title=Does self-reported hearing difficulty decrease older adults' cognitive and physical functioning? The mediating role of social isolation.
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33036703
|full-text-url=https://sci-hub.do/10.1016/j.maturitas.2020.06.011
}}
==SHMT2==
 
* {{medline-title
|title=Epigenetic regulation of the nuclear-coded [[GCAT]] and [[SHMT2]] genes confers human age-associated mitochondrial respiration defects.
|date=22.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26000717
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377050
}}
==SHOX2==
 
* {{medline-title
|title=Role of [[SHOX2]] in the development of intervertebral disc degeneration.
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26697824
|full-text-url=https://sci-hub.do/10.1002/jor.23140
}}
==SHROOM3==
 
* {{medline-title
|title=A roadmap for the genetic analysis of renal aging.
|date=10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26219736
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568960
}}
==SIGIRR==
 
* {{medline-title
|title=Anti-Inflamm-Aging Effects of Long-Term Caloric Restriction via Overexpression of [[SIGIRR]] to Inhibit NF-κB Signaling Pathway.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26431348
|full-text-url=https://sci-hub.do/10.1159/000430248
}}
==SIK3==
 
* {{medline-title
|title=Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids.
|date=25.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566214
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518561
}}
==SIL1==
 
* {{medline-title
|title=[[SIL1]], the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology.
|date=10.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29666155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992605
}}
==SIX1==
 
* {{medline-title
|title=Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27224259
|full-text-url=https://sci-hub.do/10.1111/dgd.12290
}}
==SIX2==
 
* {{medline-title
|title=Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.
|date=10.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27133132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864151
}}
==SIX4==
 
* {{medline-title
|title=Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27224259
|full-text-url=https://sci-hub.do/10.1111/dgd.12290
}}
==SIX5==
 
* {{medline-title
|title=Low Six4 and Six5 gene dosage improves dystrophic phenotype and prolongs life span of mdx mice.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27224259
|full-text-url=https://sci-hub.do/10.1111/dgd.12290
}}
==SKAP2==
 
* {{medline-title
|title=Longevity-related molecular pathways are subject to midlife "switch" in humans.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168962
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612641
}}
==SKI==
 
* {{medline-title
|title=Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29700792
|full-text-url=https://sci-hub.do/10.1007/s11684-017-0586-8
}}
==SKP1==
 
* {{medline-title
|title=Transcriptome profiling of postharvest strawberry fruit in response to exogenous auxin and abscisic acid.
|date=01.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26373937
|full-text-url=https://sci-hub.do/10.1007/s00425-015-2402-5
}}
==SLAMF7==
 
* {{medline-title
|title=Age-related differences in neuroinflammatory responses associated with a distinct profile of regulatory markers on neonatal microglia.
|date=04.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24708744
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234188
}}
==SLC12A5==
 
* {{medline-title
|title=DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28419903
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.04.006
}}
==SLC15A1==
 
* {{medline-title
|title=Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019300
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3413-x
}}
==SLC15A2==
 
* {{medline-title
|title=Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019300
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3413-x
}}
==SLC16A7==
 
* {{medline-title
|title=Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach.
|date=23.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33095951
|full-text-url=https://sci-hub.do/10.1111/jdv.17014
}}
==SLC17A3==
 
* {{medline-title
|title=Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951662
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112104
}}
==SLC17A4==
 
* {{medline-title
|title=Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951662
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112104
}}
==SLC1A5==
 
* {{medline-title
|title=[[SLC1A5]] glutamine transporter is a target of [[MYC]] and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909319
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516164
}}
==SLC22A14==
 
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
==SLC22A23==
 
* {{medline-title
|title=Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603369
|full-text-url=https://sci-hub.do/10.1111/jgh.14149
}}
==SLC24A5==
 
* {{medline-title
|title=[A question of colour].
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29384103
|full-text-url=https://sci-hub.do/10.1051/medsci/20183401020
}}
==SLC25A1==
 
* {{medline-title
|title=The hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.
|date=11.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25874378
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358699
}}
==SLC25A15==
 
* {{medline-title
|title=The hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.
|date=11.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25874378
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358699
}}
==SLC26A2==
 
* {{medline-title
|title=Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31914611
|full-text-url=https://sci-hub.do/10.1096/fj.201901040RR
}}
==SLC27A1==
 
* {{medline-title
|title=EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice.
|date=16.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28178239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480610
}}
==SLC2A4==
 
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
==SLC2A4RG==
 
* {{medline-title
|title=Genome-wide association study for lactation persistency, female fertility, longevity, and lifetime profit index traits in Holstein dairy cattle.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27889128
|full-text-url=https://sci-hub.do/10.3168/jds.2016-11770
}}
==SLC2A9==
 
* {{medline-title
|title=MicroRNA-Based Linkage between Aging and Cancer: from Epigenetics View Point.
|date=07-09.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27540517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988411
}}
==SLC30A1==
 
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
}}
==SLC30A10==
 
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
}}
==SLC30A3==
 
* {{medline-title
|title=[[SLC30A3]] and SEP15 gene polymorphisms influence the serum concentrations of zinc and selenium in mature adults.
|date=09.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25249019
|full-text-url=https://sci-hub.do/10.1016/j.nutres.2014.08.009
}}
==SLC30A5==
 
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
}}
==SLC36A4==
 
* {{medline-title
|title=The amino acid transporter [[SLC36A4]] regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28083894
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334531
}}
==SLC39A6==
 
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
}}
==SLC41A1==
 
* {{medline-title
|title=Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis.
|date=08.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31076559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535063
}}
==SLC52A2==
 
* {{medline-title
|title=Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808726
}}
==SLC52A3==
 
* {{medline-title
|title=Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808726
}}
==SLCO1B3==
 
* {{medline-title
|title=Paclitaxel-induced sensory peripheral neuropathy is associated with an [[ABCB1]] single nucleotide polymorphism and older age in Japanese.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28447211
|full-text-url=https://sci-hub.do/10.1007/s00280-017-3314-9
}}
==SLCO1C1==
 
* {{medline-title
|title=Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging.
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27815632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154615
}}
==SLIT2==
 
* {{medline-title
|title=Analysis of gene expression during aging of CGNs in culture: implication of [[SLIT2]] and [[NPY]] in senescence.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26047956
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493715
}}
==SLPI==
 
* {{medline-title
|title=Human buccal epithelium acquires microbial hyporesponsiveness at birth, a role for secretory leukocyte protease inhibitor.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25056659
|full-text-url=https://sci-hub.do/10.1136/gutjnl-2013-306149
}}
==SMAP==
 
* {{medline-title
|title=DNA integrity-protecting and survival-promoting activity of serotonergic system in sturgeon juveniles and sazans.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28321525
|full-text-url=https://sci-hub.do/10.1007/s10695-017-0360-5
}}
==SMARCA4==
 
* {{medline-title
|title=GBM-associated mutations and altered protein expression are more common in young patients.
|date=25.10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491
}}
==SMARCA5==
 
* {{medline-title
|title=The epigenetic regulator [[SIRT7]] guards against mammalian cellular senescence induced by ribosomal DNA instability.
|date=13.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052228
}}
==SMARCB1==
 
* {{medline-title
|title=High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.
|date=17.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29045843
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2017.09.085
}}
==SMARCD1==
 
* {{medline-title
|title=Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells.
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30155609
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269360
}}
==SMC1A==
 
* {{medline-title
|title=Age-related decrease of meiotic cohesins in human oocytes.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24806359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013030
}}
==SMC1B==
 
* {{medline-title
|title=Age-related decrease of meiotic cohesins in human oocytes.
|date=2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24806359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013030
}}
==SMC2==
 
* {{medline-title
|title=The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence.
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336977
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.065
}}
==SMC4==
 
* {{medline-title
|title=The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence.
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336977
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.065
}}
==SMC5==
 
* {{medline-title
|title=[[SMC5]]/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes.
|date=01.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28302748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450844
}}
==SMG6==
 
* {{medline-title
|title=Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II).
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26821332
|full-text-url=https://sci-hub.do/10.1159/000438900
}}
==SMPD1==
 
* {{medline-title
|title=Alterations in Lipid Profile of the Aging Kidney Identified by MALDI Imaging Mass Spectrometry.
|date=05.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31244212
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00108
}}
==SMURF2==
 
* {{medline-title
|title=Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
|date=2013
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24478790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567
}}
==SMYD2==
 
* {{medline-title
|title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115
}}
==SNAI2==
 
* {{medline-title
|title=Reawakening of dormant estrogen-dependent human breast cancer cells by bone marrow stroma secretory senescence.
|date=17.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119678
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098600
}}
==SNAP23==
 
* {{medline-title
|title=Effects of immobilization and aerobic training on proteins related to intramuscular substrate storage and metabolism in young and older men.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26626913
|full-text-url=https://sci-hub.do/10.1007/s00421-015-3302-x
}}
==SND1==
 
* {{medline-title
|title=[Downregulation of [[SND1]] Expression Accelerates Cell Senescence of Human Diploid Fibroblasts 2BS via Modulating the SASP].
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32543144
|full-text-url=https://sci-hub.do/10.12182/20200560504
}}
==SNN==
 
* {{medline-title
|title=Evolving Spiking Neural Networks for Recognition of Aged Voices.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27049449
|full-text-url=https://sci-hub.do/10.1016/j.jvoice.2016.02.019
}}
==SNX15==
 
* {{medline-title
|title=[[SNX15]] Regulates Cell Surface Recycling of [[APP]] and Aβ Generation.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26115702
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691577
}}
==SOBP==
 
* {{medline-title
|title=Lifetime increased cancer risk in mice following exposure to clinical proton beam-generated neutrons.
|date=01.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24725699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298825
}}
==SORCS2==
 
* {{medline-title
|title=Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329260
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013013
}}
==SORT1==
 
* {{medline-title
|title=Soluble sortilin is present in excess and positively correlates with progranulin in CSF of aging individuals.
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27612602
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.09.002
}}
==SOS1==
 
* {{medline-title
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice.
|date=21.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397
}}
==SOX10==
 
* {{medline-title
|title=[[SOX10]] Distinguishes Pilocytic and Pilomyxoid Astrocytomas From Ependymomas but Shows No Differences in Expression Level in Ependymomas From Infants Versus Older Children or Among Molecular Subgroups.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26945037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009481
}}
==SOX11==
 
* {{medline-title
|title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
|date=10.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741
}}
==SOX13==
 
* {{medline-title
|title=In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases.
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520345
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09834-1
}}
==SOX17==
 
* {{medline-title
|title=[[SOX17]] Regulates Conversion of Human Fibroblasts Into Endothelial Cells and Erythroblasts by Dedifferentiation Into [[CD34]]  Progenitor Cells.
|date=20.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28381471
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472005
}}
==SP2==
 
* {{medline-title
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0
}}
==SP3==
 
* {{medline-title
|title=A genome-wide scan reveals important roles of DNA methylation in human longevity by regulating age-related disease genes.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25793257
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368809
}}
==SP5==
 
* {{medline-title
|title=Novel 5-HT5A receptor antagonists ameliorate scopolamine-induced working memory deficit in mice and reference memory impairment in aged rats.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25837935
|full-text-url=https://sci-hub.do/10.1016/j.jphs.2015.02.006
}}
==SP7==
 
* {{medline-title
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
}}
==SP8==
 
* {{medline-title
|title=Molecular control of two novel migratory paths for CGE-derived interneurons in the developing mouse brain.
|date=15.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27034423
|full-text-url=https://sci-hub.do/10.1242/dev.131102
}}
==SPAG9==
 
* {{medline-title
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6
}}
==SPATS2L==
 
* {{medline-title
|title=Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818258
}}
==SPG21==
 
* {{medline-title
|title=Loss of Maspardin Attenuates the Growth and Maturation of Mouse Cortical Neurons.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26978163
|full-text-url=https://sci-hub.do/10.1159/000443666
}}
==SPG7==
 
* {{medline-title
|title=Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration.
|date=21.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467464
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833341
}}
==SPHK1==
 
* {{medline-title
|title=Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30997640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425817
}}
==SPHK2==
 
* {{medline-title
|title=Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30886000
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446199
}}
==SPI1==
 
* {{medline-title
|title=Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-[[MADD]] locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066205
}}
==SPN==
 
* {{medline-title
|title=[Identification of single nucleotide polymorphisms in centenarians].
|date=05-06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26541311
|full-text-url=https://sci-hub.do/10.1016/j.regg.2015.09.006
}}
==SPX==
 
* {{medline-title
|title=Phosphorus remobilization from rice flag leaves during grain filling: an RNA-seq study.
|date=01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27228336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253468
}}
==SRL==
 
* {{medline-title
|title=Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment.
|date=04-06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32432936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250001
}}
==SRPK1==
 
* {{medline-title
|title=[Age-related changes in the content of serine-arginine protein kinase 1 ([[SRPK1]]) in human dermis.]
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322729
 
}}
==SRSF1==
 
* {{medline-title
|title=Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037605
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2018.06.029
}}
==SRSF10==
 
* {{medline-title
|title=Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25187368
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303971
}}
==SRSF2==
 
* {{medline-title
|title=Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27147278
|full-text-url=https://sci-hub.do/10.1111/ejh.12771
}}
==SRSF3==
 
* {{medline-title
|title=Alternative polyadenylation dependent function of splicing factor [[SRSF3]] contributes to cellular senescence.
|date=04.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30835716
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428108
}}
==SSBP2==
 
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
==SSTR3==
 
* {{medline-title
|title=Type 3 Adenylyl Cyclase and Somatostatin Receptor 3 Expression Persists in Aged Rat Neocortical and Hippocampal Neuronal Cilia.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27303293
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885836
}}
==SSX2==
 
* {{medline-title
|title=Ectopic expression of cancer/testis antigen [[SSX2]] induces DNA damage and promotes genomic instability.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25363656
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528659
}}
==ST18==
 
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
}}
==STAT4==
 
* {{medline-title
|title=RNA-Seq analysis reveals new evidence for inflammation-related changes in aged kidney.
|date=24.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27153548
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058662
}}
==STC1==
 
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
==STC2==
 
* {{medline-title
|title=Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and [[STC2]].
|date=05.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31761296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904802
}}
==STK11==
 
* {{medline-title
|title=A Multigene Test Could Cost-Effectively Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407996
|full-text-url=https://sci-hub.do/10.1016/j.jval.2017.01.006
}}
==STK32C==
 
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
==STK38L==
 
* {{medline-title
|title=[Role of [[PLAT]], [[PKHD1L1]], [[STK38L]] and [[TEAD1]] genes Alu-polymorphism for longevity].
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28556638
 
}}
==STOML2==
 
* {{medline-title
|title=Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29201274
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672147
}}
==STRA6==
 
* {{medline-title
|title=Transport of vitamin A across blood-tissue barriers is facilitated by [[STRA6]].
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27189978
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970611
}}
==STX17==
 
* {{medline-title
|title=Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and [[XIAP]].
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251987
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.05.017
}}
==SUCNR1==
 
* {{medline-title
|title=[The effect of Mexidol on cerebral mitochondriogenesis at a young age and during aging].
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105271
|full-text-url=https://sci-hub.do/10.17116/jnevro202012001162
}}
==SUGCT==
 
* {{medline-title
|title=Knockout of the non-essential gene [[SUGCT]] creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31722069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426296
}}
==SULT1A1==
 
* {{medline-title
|title=Bayesian association scan reveals loci associated with human lifespan and linked biomarkers.
|date=27.07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28748955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537485
}}
==SULT1E1==
 
* {{medline-title
|title=Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes.
|date=02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28153492
|full-text-url=https://sci-hub.do/10.1016/j.dmpk.2016.10.409
}}
==SUMO1==
 
* {{medline-title
|title=[[SUMO1]]-conjugation is altered during normal aging but not by increased amyloid burden.
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29633471
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052395
}}
==SUMO2==
 
* {{medline-title
|title=KSHV latent protein LANA2 inhibits sumo2 modification of p53.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25607652
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615004
}}
==SUN1==
 
* {{medline-title
|title=Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging.
|date=26.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397528
}}
==SUN2==
 
* {{medline-title
|title=Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging.
|date=26.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397528
}}
==SV2B==
 
* {{medline-title
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
}}
==SV2C==
 
* {{medline-title
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
}}
==SYCP2==
 
* {{medline-title
|title=Accelerated reproductive aging in females lacking a novel centromere protein [[[[SYCP2]]L]].
|date=15.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26362258
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614708
}}
==SYCP2L==
 
* {{medline-title
|title=Accelerated reproductive aging in females lacking a novel centromere protein [[[[SYCP2]]L]].
|date=15.11.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26362258
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614708
}}
==SYCP3==
 
* {{medline-title
|title=Effects of Saikokaryukotsuboreito on Spermatogenesis and Fertility in Aging Male Mice.
|date=05.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26996482
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819307
}}
==SYNE1==
 
* {{medline-title
|title=Nesprin-1 impact on tumorigenic cell phenotypes.
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31741263
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05184-w
}}
==SYNJ2==
 
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
==SYT1==
 
* {{medline-title
|title=Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29670520
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893842
}}
==SYT4==
 
* {{medline-title
|title=Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans.
|date=06.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26337083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745765
}}
==SYT7==
 
* {{medline-title
|title=Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells.
|date=28.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30647108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367206
}}
==TAAR1==
 
* {{medline-title
|title=Minimal Age-Related Alterations in Behavioral and Hematological Parameters in Trace Amine-Associated Receptor 1 ([[TAAR1]]) Knockout Mice.
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31399838
|full-text-url=https://sci-hub.do/10.1007/s10571-019-00721-4
}}
==TAC3==
 
* {{medline-title
|title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460
}}
==TACR3==
 
* {{medline-title
|title=Association of a neurokinin 3 receptor polymorphism with the anterior basal forebrain.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25976010
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2014.12.031
}}
==TAF15==
 
* {{medline-title
|title=FET proteins regulate lifespan and neuronal integrity.
|date=27.04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27117089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846834
}}
==TAF7==
 
* {{medline-title
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|date=22.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
}}
==TAF7L==
 
* {{medline-title
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|date=22.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
}}
==TAP2==
 
* {{medline-title
|title=Lifespan of mice and primates correlates with immunoproteasome expression.
|date=05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25866968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463211
}}
==TAS1R2==
 
* {{medline-title
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects.
|date=18.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
}}
==TBC1D4==
 
* {{medline-title
|title=Effects of Exercise Training on Regulation of Skeletal Muscle Glucose Metabolism in Elderly Men.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25991826
|full-text-url=https://sci-hub.do/10.1093/gerona/glv012
}}
==TBR1==
 
* {{medline-title
|title=DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28419903
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.04.006
}}
==TBX21==
 
* {{medline-title
|title=[Study of gene expression of transcription factors T cells during aging].
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28509479
 
}}
==TBX3==
 
* {{medline-title
|title=Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.
|date=29.05.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24876127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071561
}}
==TCERG1==
 
* {{medline-title
|title=The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity.
|date=17.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31316054
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637209
}}
==TCF15==
 
* {{medline-title
|title=Loss of Neurogenesis in Aging Hydra.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586502
}}
==TCF21==
 
* {{medline-title
|title=Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3.
|date=22.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29748384
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016453
}}
==TCF4==
 
* {{medline-title
|title=Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27878761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441979
}}
==TCF7L1==
 
* {{medline-title
|title=[[TCF7L1]] promotes skin tumorigenesis independently of β-catenin through induction of [[LCN2]].
|date=03.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28467300
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438253
}}
==TCTA==
 
* {{medline-title
|title=Exciplex-Forming Cohost for High Efficiency and High Stability Phosphorescent Organic Light-Emitting Diodes.
|date=17.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29265796
|full-text-url=https://sci-hub.do/10.1021/acsami.7b15034
}}
==TDRD7==
 
* {{medline-title
|title=RNA granule component [[TDRD7]] gene polymorphisms in a Han Chinese population with age-related cataract.
|date=02.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24435515
|full-text-url=https://sci-hub.do/10.1177/0300060513504702
}}
==TECPR2==
 
* {{medline-title
|title=Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging.
|date=01-03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30681437
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000294
}}
==TEF==
 
* {{medline-title
|title=Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32189112
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09869-9
}}
==TEN1==
 
* {{medline-title
|title=Stimulation of cell proliferation by glutathione monoethyl ester in aged bone marrow stromal cells is associated with the assistance of [[TERT]] gene expression and telomerase activity.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27251157
|full-text-url=https://sci-hub.do/10.1007/s11626-016-0021-5
}}
==TEP1==
 
* {{medline-title
|title=[Influence of Age on the Susceptibility of  Anopheles stephensi to Plasmodium berghei Infection].
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30141604
 
}}
==TFAP2A==
 
* {{medline-title
|title=Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25763115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356053
}}
==TFPI==
 
* {{medline-title
|title=Identification of cardiovascular health gene variants related to longevity in a Chinese population.
|date=07.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32897244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521493
}}
==TGDS==
 
* {{medline-title
|title=The evaluation and design of a short depression screening tool in Turkish older adults.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29560848
|full-text-url=https://sci-hub.do/10.1017/S1041610218000236
}}
==TGFB2==
 
* {{medline-title
|title=Seminal plasma transforming growth factor-β, activin A and follistatin fluctuate within men over time.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27609985
|full-text-url=https://sci-hub.do/10.1093/humrep/dew185
}}
==TGFB3==
 
* {{medline-title
|title=Seminal plasma transforming growth factor-β, activin A and follistatin fluctuate within men over time.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27609985
|full-text-url=https://sci-hub.do/10.1093/humrep/dew185
}}
==TGFBR1==
 
* {{medline-title
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
}}
==TGFBR2==
 
* {{medline-title
|title=TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
|date=08.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31068441
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102613
}}
==TGM2==
 
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
==THADA==
 
* {{medline-title
|title=Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.
|date=29.09.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598835
}}
==THBS1==
 
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
==THBS4==
 
* {{medline-title
|title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment.
|date=18.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664
}}
==THEMIS==
 
* {{medline-title
|title=Lifetime benefits of early detection and treatment of diabetic kidney disease.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31150444
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544227
}}
==THPO==
 
* {{medline-title
|title=Thrombopoietin is associated with δ's intercept, and only in Non-Hispanic Whites.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27239547
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879650
}}
==TINF2==
 
* {{medline-title
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
}}
==TJP1==
 
* {{medline-title
|title=Morphological and immunohistochemical characteristics of the equine corneal epithelium.
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900071
}}
==TLR6==
 
* {{medline-title
|title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149
}}
==TM9SF1==
 
* {{medline-title
|title=Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats.
|date=06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286171
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501279
}}
==TMEM135==
 
* {{medline-title
|title=Mouse [i]Tmem135[/i] mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies.
|date=15.11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27863209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117855
}}
==TMEM18==
 
* {{medline-title
|title=Sequence variation in [[TMEM18]] in association with body mass index: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951660
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135723
}}
==TMEM51==
 
* {{medline-title
|title=Genome-wide analysis of DNA methylation profiles in a senescence-accelerated mouse prone 8 brain using whole-genome bisulfite sequencing.
|date=01.06.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28130229
|full-text-url=https://sci-hub.do/10.1093/bioinformatics/btx040
}}
==TNFRSF11B==
 
* {{medline-title
|title=Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II).
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26821332
|full-text-url=https://sci-hub.do/10.1159/000438900
}}
==TNFRSF1A==
 
* {{medline-title
|title=Consumption of protein-enriched milk has minor effects on inflammation in older adults-A 12-week double-blind randomized controlled trial.
|date=03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28163108
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.01.011
}}
==TNFSF10==
 
* {{medline-title
|title=Role of mitochondrial function in cell death and body metabolism.
|date=01.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27100503
|full-text-url=https://sci-hub.do/10.2741/4453
}}
==TNFSF13==
 
* {{medline-title
|title=Genome-wide methylation analysis reveals differentially methylated loci that are associated with an age-dependent increase in bovine fibroblast response to LPS.
|date=25.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28545453
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5445414
}}
==TNFSF15==
 
* {{medline-title
|title=Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269026
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.09.015
}}
==TNK1==
 
* {{medline-title
|title=Role of [[CLU]], [[PICALM]], and [[TNK1]] Genotypes in Aging With and Without Alzheimer's Disease.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28631188
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0547-x
}}
==TNNI1==
 
* {{medline-title
|title=Regular aerobic exercise-ameliorated troponin I carbonylation to mitigate aged rat soleus muscle functional recession.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820991
|full-text-url=https://sci-hub.do/10.1113/EP087564
}}
==TNNT1==
 
* {{medline-title
|title=Improved knee extensor strength with resistance training associates with muscle specific miRNAs in older adults.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25560803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314447
}}
==TNP1==
 
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
}}
==TNP2==
 
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
}}
==TNPO3==
 
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
==TNS3==
 
* {{medline-title
|title=Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27329260
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013013
}}
==TOR2A==
 
* {{medline-title
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
|date=05.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
}}
==TP53BP1==
 
* {{medline-title
|title=Induction of DNA double-strand breaks and cellular senescence by human respiratory syncytial virus.
|date=18.05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26809688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871660
}}
==TP53INP1==
 
* {{medline-title
|title=[[TP53INP1]] deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling.
|date=02.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559202
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320535
}}
==TP53RK==
 
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|date=11.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
}}
==TP73==
 
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
==TPP2==
 
* {{medline-title
|title=Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency.
|date=29.01.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25414442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463807
}}
==TPRKB==
 
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|date=11.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
}}
==TPX2==
 
* {{medline-title
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
}}
==TRADD==
 
* {{medline-title
|title=TNF/TNFR₁ pathway and endoplasmic reticulum stress are involved in ofloxacin-induced apoptosis of juvenile canine chondrocytes.
|date=15.04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24582689
|full-text-url=https://sci-hub.do/10.1016/j.taap.2014.02.003
}}
==TRAF6==
 
* {{medline-title
|title=Elevated A20 contributes to age-dependent macrophage dysfunction in the lungs.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24440463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989429
}}
==TRAV1-2==
 
* {{medline-title
|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826
}}
==TRAV27==
 
* {{medline-title
|title=Perturbed CD8  T cell immunity across universal influenza epitopes in the elderly.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928269
|full-text-url=https://sci-hub.do/10.1189/jlb.5MA0517-207R
}}
==TRBV19==
 
* {{medline-title
|title=Perturbed CD8  T cell immunity across universal influenza epitopes in the elderly.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928269
|full-text-url=https://sci-hub.do/10.1189/jlb.5MA0517-207R
}}
==TREM1==
 
* {{medline-title
|title=A [[TREM1]] variant alters the accumulation of Alzheimer-related amyloid pathology.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25545807
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461024
}}
==TRIB2==
 
* {{medline-title
|title=[[TRIB2]] functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling.
|date=12.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291992
}}
==TRIB3==
 
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
==TRIM21==
 
* {{medline-title
|title=[[TRIM21]] overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32064156
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017742
}}
==TRIM27==
 
* {{medline-title
|title=[[TRIM27]] Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination.
|date=04.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33251042
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666371
}}
==TRIOBP==
 
* {{medline-title
|title=A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27764096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072625
}}
==TRO==
 
* {{medline-title
|title=Post-mortem findings and piglet mortality in relation to strategic use of straw at farrowing.
|date=01.05.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25792335
|full-text-url=https://sci-hub.do/10.1016/j.prevetmed.2015.02.023
}}
==TRPC1==
 
* {{medline-title
|title=Ca  entry via [[TRPC1]] is essential for cellular differentiation and modulates secretion via the SNARE complex.
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397
}}
==TRPC7==
 
* {{medline-title
|title=Nociceptive transient receptor potential canonical 7 ([[TRPC7]]) mediates aging-associated tumorigenesis induced by ultraviolet B.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31755176
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974716
}}
==TRPM5==
 
* {{medline-title
|title=Genetic strategies to analyze primary TRP channel-expressing cells in mice.
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28571899
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2017.05.009
}}
==TRPS1==
 
* {{medline-title
|title=miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence.
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074095
|full-text-url=https://sci-hub.do/10.1002/jcb.28862
}}
==TRPV2==
 
* {{medline-title
|title=The role of transient receptor potential vanilloid 2 channel in cardiac aging.
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27804106
|full-text-url=https://sci-hub.do/10.1007/s40520-016-0663-x
}}
==TSG101==
 
* {{medline-title
|title=Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging.
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220525
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116582
}}
==TSHR==
 
* {{medline-title
|title=TSH-independent release of thyroid hormones through cold exposure in aging rats.
|date=27.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163760
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685681
}}
==TSPYL5==
 
* {{medline-title
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
}}
==TSSK6==
 
* {{medline-title
|title=DNA methylation-based age prediction from saliva: High age predictability by combination of 7 CpG markers.
|date=07.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28419903
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.04.006
}}
==TWIST2==
 
* {{medline-title
|title=DNA methylation abnormalities at gene promoters are extensive and variable in the elderly and phenocopy cancer cells.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24858281
|full-text-url=https://sci-hub.do/10.1096/fj.13-246173
}}
==TXK==
 
* {{medline-title
|title=Phenotypic characteristics of aged [[CD4]]  [[CD28]]  T lymphocytes are determined by changes in the whole-genome DNA methylation pattern.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28026094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334526
}}
==TXN==
 
* {{medline-title
|title=Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice.
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29141658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688691
}}
==TXNDC5==
 
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
==TXNRD3==
 
* {{medline-title
|title=Mitochondrial thioredoxin reductase 2 is elevated in long-lived primate as well as rodent species and extends fly mean lifespan.
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28474396
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506402
}}
==TYK2==
 
* {{medline-title
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
}}
==TYMS==
 
* {{medline-title
|title=C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins.
|date=03.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26854551
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789167
}}
==TYRO3==
 
* {{medline-title
|title=The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia ([i]anx[/i]) mutation.
|date=01.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28093506
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451163
}}
==UACA==
 
* {{medline-title
|title=Knockdown of [i][[UACA]][/i] inhibitsproliferation and invasion and promotes senescence of hepatocellular carcinoma cells.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31949867
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962967
}}
==UAP1==
 
* {{medline-title
|title=Functional inactivation of UDP-N-acetylglucosamine pyrophosphorylase 1 ([[UAP1]]) induces early leaf senescence and defence responses in rice.
|date=02.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25399020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321554
}}
==UBC==
 
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
==UBE2D2==
 
* {{medline-title
|title=Stable reference genes in granulosa cells of bovine dominant follicles during follicular growth, FSH stimulation and maternal aging.
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25426842
|full-text-url=https://sci-hub.do/10.1071/RD14089
}}
==UBE2E3==
 
* {{medline-title
|title=Loss of the ubiquitin conjugating enzyme [[UBE2E3]] induces cellular senescence.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29879550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007080
}}
==UBE2N==
 
* {{medline-title
|title=Aged monkey brains reveal the role of ubiquitin-conjugating enzyme [[UBE2N]] in the synaptosomal accumulation of mutant huntingtin.
|date=01.03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25343992
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321442
}}
==UBE4B==
 
* {{medline-title
|title=CircRNAs in the tree shrew ([i]Tupaia belangeri[/i]) brain during postnatal development and aging.
|date=30.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29723158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940110
}}
==UBN1==
 
* {{medline-title
|title=O-linked N-acetylglucosamine transferase ([[OGT]]) interacts with the histone chaperone [[HIRA]] complex and regulates nucleosome assembly and cellular senescence.
|date=07.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27217568
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988580
}}
==UBP1==
 
* {{medline-title
|title=Expression of potato RNA-binding proteins StUBA2a/b and StUBA2c induces hypersensitive-like cell death and early leaf senescence in Arabidopsis.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25944928
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473998
}}
==UBQLN2==
 
* {{medline-title
|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.
|date=24.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225
}}
==UBTD1==
 
* {{medline-title
|title=[[UBTD1]] induces cellular senescence through an [[UBTD1]]-Mdm2/p53 positive feedback loop.
|date=03.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25382750
|full-text-url=https://sci-hub.do/10.1002/path.4478
}}
==UBTF==
 
* {{medline-title
|title=Age-associated dysregulation of protein metabolism in the mammalian oocyte.
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994181
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676066
}}
==UCHL3==
 
* {{medline-title
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|date=12.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
}}
==UCHL5==
 
* {{medline-title
|title=Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system.
|date=07.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27260470
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2016.03.008
}}
==UCN==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==UCN3==
 
* {{medline-title
|title=Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise-induced threshold shift.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31270820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852351
}}
==UGT1A6==
 
* {{medline-title
|title=Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain.
|date=07.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25953521
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468441
}}
==UGT2B28==
 
* {{medline-title
|title=Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a [[UGT2B28]] genomic variation.
|date=05.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31805979
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896495
}}
==UGT2B7==
 
* {{medline-title
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
}}
==ULK2==
 
* {{medline-title
|title=miR-26a suppresses autophagy in swine Sertoli cells by targeting [[ULK2]].
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29761550
|full-text-url=https://sci-hub.do/10.1111/rda.13177
}}
==UNC5C==
 
* {{medline-title
|title=Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28441426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404753
}}
==UPF1==
 
* {{medline-title
|title=Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity.
|date=21.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28824175
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563511
}}
==UPRT==
 
* {{medline-title
|title=[[UPRT]], a suicide-gene therapy candidate in higher eukaryotes, is required for Drosophila larval growth and normal adult lifespan.
|date=14.08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26271729
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536494
}}
==UQCRC1==
 
* {{medline-title
|title=Effect of testosterone on markers of mitochondrial oxidative phosphorylation and lipid metabolism in muscle of aging men with subnormal bioavailable testosterone.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24760536
|full-text-url=https://sci-hub.do/10.1530/EJE-14-0006
}}
==UQCRFS1==
 
* {{medline-title
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway.
|date=04.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201
}}
==USF1==
 
* {{medline-title
|title=The rs2516839 variation of [[USF1]] gene is associated with 4-year mortality of nonagenarian women: The Vitality 90  study.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30203836
|full-text-url=https://sci-hub.do/10.1111/ahg.12282
}}
==USF2==
 
* {{medline-title
|title=Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice.
|date=15.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30084918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454504
}}
==USP10==
 
* {{medline-title
|title=Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c-kit( ) cardiac progenitor cells by promoting miR-675.
|date=08.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27062045
|full-text-url=https://sci-hub.do/10.1111/jpi.12331
}}
==USP14==
 
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
==USP15==
 
* {{medline-title
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i].
|date=29.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047
}}
==USP28==
 
* {{medline-title
|title=Genetic interrogation of replicative senescence uncovers a dual role for [[USP28]] in coordinating the p53 and [[GATA4]] branches of the senescence program.
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710139
}}
==USP30==
 
* {{medline-title
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i].
|date=29.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047
}}
==USP4==
 
* {{medline-title
|title=Increased Expression of Ubiquitin-Specific Protease 4 Participates in Neuronal Apoptosis After Intracerebral Hemorrhage in Adult Rats.
|date=04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27114249
|full-text-url=https://sci-hub.do/10.1007/s10571-016-0375-y
}}
==USP8==
 
* {{medline-title
|title=Inhibition of the deubiquitinase [[USP8]] corrects a Drosophila [[PINK1]] model of mitochondria dysfunction.
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467245
}}
==UTF1==
 
* {{medline-title
|title=miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1.
|date=09.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28277545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386568
}}
==UVSSA==
 
* {{medline-title
|title=A C. elegans homolog for the UV-hypersensitivity syndrome disease gene [[UVSSA]].
|date=05.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27043179
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886821
}}
==VAMP2==
 
* {{medline-title
|title=Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission.
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29950309
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068464
}}
==VAMP8==
 
* {{medline-title
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327
}}
==VAPB==
 
* {{medline-title
|title=Transforming Cytosolic Proteins into "Insoluble" and Membrane-toxic Forms Triggering Diseases/Aging by Genetic, Pathological or Environmental Factors.
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28190398
|full-text-url=https://sci-hub.do/10.2174/0929866524666170209154001
}}
==VAV3==
 
* {{medline-title
|title=Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans.
|date=06.10.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26337083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745765
}}
==VCL==
 
* {{medline-title
|title=The effects of different preservation methods on ide (Leuciscus idus) sperm and the longevity of sperm movement.
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397922
|full-text-url=https://sci-hub.do/10.1016/j.cryobiol.2018.01.014
}}
==VDAC3==
 
* {{medline-title
|title=[[VDAC3]] As a Potential Marker of Mitochondrial Status Is Involved in Cancer and Pathology.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28066720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179545
}}
==VEGFC==
 
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
==VEGFD==
 
* {{medline-title
|title=Single-Arm Resistance Training Study to Determine the Relationship between Training Outcomes and Muscle Growth Factor mRNAs in Older Adults Consuming Numerous Medications and Supplements.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29380855
|full-text-url=https://sci-hub.do/10.1007/s12603-017-0913-4
}}
==VHLL==
 
* {{medline-title
|title=The Monetary Valuation of Lifetime Health Improvement and Life Expectancy Gains in Turkey.
|date=29.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28961227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664652
}}
==VIPR2==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==VPREB3==
 
* {{medline-title
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|date=19.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
}}
==VPS13C==
 
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
==VPS13D==
 
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
==VPS26A==
 
* {{medline-title
|title=Characterization of novel markers of senescence and their prognostic potential in cancer.
|date=20.11.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25412306
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260747
}}
==VPS37B==
 
* {{medline-title
|title=Identification of HIV infection-related DNA methylation sites and advanced epigenetic aging in HIV-positive, treatment-naive U.S. veterans.
|date=20.02.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27922854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5263111
}}
==VSIG4==
 
* {{medline-title
|title=Immune checkpoint protein [[VSIG4]] as a biomarker of aging in murine adipose tissue.
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576241
}}
==VSX1==
 
* {{medline-title
|title=Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics.
|date=08.06.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27267879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897877
}}
==WASL==
 
* {{medline-title
|title=Loss of Wasl improves pancreatic cancer outcome.
|date=21.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434991
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259520
}}
==WDR48==
 
* {{medline-title
|title=Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
|date=15.04.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25648963
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513651
}}
==WDR5==
 
* {{medline-title
|title=Inhibition of the H3K4 methyltransferase MLL1/[[WDR5]] complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16 .
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570196
|full-text-url=https://sci-hub.do/10.1016/j.kint.2019.06.021
}}
==WDR73==
 
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|date=11.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
}}
==WDSUB1==
 
* {{medline-title
|title=The complex genetics of gait speed: genome-wide meta-analysis approach.
|date=10.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28077804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310665
}}
==WFDC2==
 
* {{medline-title
|title=Differences in biomarkers and molecular pathways according to age for patients with HFrEF.
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002110
|full-text-url=https://sci-hub.do/10.1093/cvr/cvaa279
}}
==WIF1==
 
* {{medline-title
|title=Identification of the mechanisms by which age alters the mechanosensitivity of mesenchymal stromal cells on substrates of differing stiffness: Implications for osteogenesis and angiogenesis.
|date=15.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28216301
|full-text-url=https://sci-hub.do/10.1016/j.actbio.2017.02.031
}}
==WNK1==
 
* {{medline-title
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4
}}
==WNK4==
 
* {{medline-title
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4
}}
==WNT10A==
 
* {{medline-title
|title=Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development.
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31964233
|full-text-url=https://sci-hub.do/10.1089/scd.2019.0260
}}
==WNT3==
 
* {{medline-title
|title=Role of CD133 Molecule in Wnt Response and Renal Repair.
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29431914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827750
}}
==WNT7A==
 
* {{medline-title
|title=Exogenous Expression of [[WNT7A]] in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436833
|full-text-url=https://sci-hub.do/10.2174/1871520620666200521114100
}}
==XAF1==
 
* {{medline-title
|title=[[XIAP]]-associating factor 1, a transcriptional target of [[BRD7]], contributes to endothelial cell senescence.
|date=02.02.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868675
}}
==XCL1==
 
* {{medline-title
|title=Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834936
|full-text-url=https://sci-hub.do/10.1016/j.patbio.2015.03.002
}}
==XG==
 
* {{medline-title
|title=The effect of administration media on palatability and ease of swallowing of multiparticulate formulations.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30170024
|full-text-url=https://sci-hub.do/10.1016/j.ijpharm.2018.08.021
}}
==XK==
 
* {{medline-title
|title=Neurodegeneration in the elderly - When the blood type matters: An overview of the McLeod syndrome with focus on hematological features.
|date=06.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25934153
|full-text-url=https://sci-hub.do/10.1016/j.transci.2015.04.007
}}
==XPO1==
 
* {{medline-title
|title=Nuclear Export Inhibition Enhances HLH-30/[[TFEB]] Activity, Autophagy, and Lifespan.
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768192
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991088
}}
==YBX2==
 
* {{medline-title
|title=Preovulatory Aging In Vivo and In Vitro Affects Maturation Rates, Abundance of Selected Proteins, Histone Methylation Pattern and Spindle Integrity in Murine Oocytes.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27611906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017692
}}
==YES1==
 
* {{medline-title
|title=Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies.
|date=20.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30341976
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224233
}}
==YY1==
 
* {{medline-title
|title=Low mitochondrial DNA content associates with familial longevity: the Leiden Longevity Study.
|date=06.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24554339
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082602
}}
==ZAP70==
 
* {{medline-title
|title=Increased [[ZAP70]] Is Involved in Dry Skin Pruritus in Aged Mice.
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27195291
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852331
}}
==ZBED6==
 
* {{medline-title
|title=Correlation between [[ZBED6]] Gene Upstream CpG Island methylation and mRNA expression in cattle.
|date=03.04.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27532432
|full-text-url=https://sci-hub.do/10.1080/10495398.2016.1212060
}}
==ZFHX3==
 
* {{medline-title
|title=Shift work, DNA methylation and epigenetic age.
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30879037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857743
}}
==ZFP36L1==
 
* {{medline-title
|title=Zinc finger protein [[ZFP36L1]] promotes osteoblastic differentiation but represses adipogenic differentiation of mouse multipotent cells.
|date=28.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28206953
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400528
}}
==ZFPM2==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==ZNF14==
 
* {{medline-title
|title=Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model.
|date=07.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24496748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209016
}}
==ZNF207==
 
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
==ZNF367==
 
* {{medline-title
|title=RNA-seq of the aging brain in the short-lived fish N. furzeri - conserved pathways and novel genes associated with neurogenesis.
|date=12.2014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25059688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326923
}}
==ZNF396==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==ZNF467==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==ZNF616==
 
* {{medline-title
|title=Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence.
|date=2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26029164
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432801
}}
==ZNF704==
 
* {{medline-title
|title=Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index.
|date=08.2015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25758594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506316
}}
==ZP2==
 
* {{medline-title
|title=Melatonin improves the fertilization ability of post-ovulatory aged mouse oocytes by stabilizing ovastacin and Juno to promote sperm binding and fusion.
|date=01.03.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28137755
|full-text-url=https://sci-hub.do/10.1093/humrep/dew362
}}
==ZRSR2==
 
* {{medline-title
|title=Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy.
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27147278
|full-text-url=https://sci-hub.do/10.1111/ejh.12771
}}
}}
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