Aging genes 5-9: различия между версиями
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(Новая страница: «__NOTOC__ * Genes with 10 and more publications * Genes with 5-9 publications * Aging genes 1-4|Genes w...») |
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__NOTOC__ | __NOTOC__ | ||
* [[Aging genes | * [[Aging genes 300|Genes with 300 and more publications]] | ||
* [[Aging genes 200-299|Genes with 200-299 publications]] | |||
* [[Aging genes 100-199|Genes with 100-199 publications]] | |||
* [[Aging genes 90-99|Genes with 90-99 publications]] | |||
* [[Aging genes 80-89|Genes with 80-89 publications]] | |||
* [[Aging genes 70-79|Genes with 70-79 publications]] | |||
* [[Aging genes 60-69|Genes with 60-69 publications]] | |||
* [[Aging genes 50-59|Genes with 50-59 publications]] | |||
* [[Aging genes 40-49|Genes with 40-49 publications]] | |||
* [[Aging genes 30-39|Genes with 30-39 publications]] | |||
* [[Aging genes 20-29|Genes with 20-29 publications]] | |||
* [[Aging genes 10-19|Genes with 10-19 publications]] | |||
* [[Aging genes 5-9|Genes with 5-9 publications]] | * [[Aging genes 5-9|Genes with 5-9 publications]] | ||
* [[Aging genes 1- | * [[Aging genes 3-4|Genes with 3-4 publications]] | ||
* [[Aging genes 1-2|Genes with 1-2 publications]] | |||
* [[Aging_genes_A-Z_table]] | |||
== | ==ARNT== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Loss of [[ARNT]] in skeletal muscle limits muscle regeneration in aging. | ||
|date= | |date=12.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33064329 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1096/fj.202000761RR | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[Arylhydrocarbon receptor nuclear translocator ([[ARNT]]) in human skin during aging.] | ||
|date=2020 | |date=2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593246 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The E3 ubiquitin ligase [[STUB1]] attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1. | ||
|date= | |date=03.04.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041778 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135990 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Deficiency of Bmal1 disrupts the diurnal rhythm of haemostasis. | ||
|date= | |date=04.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30610898 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.12.017 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling. | ||
|date= | |date=02.11.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30217816 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222112 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Aging and chromatoid body assembly: Are these two physiological events linked? | ||
|date= | |date=07.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29958504 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108056 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Deficiency of circadian clock protein BMAL1 in mice results in a low bone mass phenotype. | ||
|date= | |date=03.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26789548 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755907 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Circadian clocks govern calorie restriction-mediated life span extension through BMAL1- and IGF-1-dependent mechanisms. | ||
|date= | |date=04.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26700733 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799504 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Whole blood thrombin generation in Bmal1-deficient mice. | ||
|date= | |date=08.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24740693 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1160/TH13-11-0910 | ||
}} | }} | ||
== | ==BMP2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[GREM1]] inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. | ||
|date= | |date=09.03.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151168 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1080/03008207.2020.1736054 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells. | ||
|date=2020 | |date=2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32126555 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1159/000504298 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging. | ||
|date= | |date=03.12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352426 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264619 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Synthesis of Extracellular Pyrophosphate Increases in Vascular Smooth Muscle Cells During Phosphate-Induced Calcification. | ||
|date= | |date=09.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30002059 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.311444 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-Related Insulin-Like Growth Factor Binding Protein-4 Overexpression Inhibits Osteogenic Differentiation of Rat Mesenchymal Stem Cells. | ||
|date= | |date=2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28595186 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1159/000477873 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. | ||
|date= | |date=06.04.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28382965 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382695 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Vaccination with [[DKK1]]-derived peptides promotes bone formation and bone mass in an aged mouse osteoporosis model. | ||
|date= | |date=08.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24907907 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/s00223-014-9875-2 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Enhanced tissue regeneration potential of juvenile articular cartilage. | ||
|date= | |date=11.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24043472 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1177/0363546513502945 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-related CXC chemokine receptor-4-deficiency impairs osteogenic differentiation potency of mouse bone marrow mesenchymal stromal stem cells. | ||
|date= | |date=08.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23742988 | ||
|full-text-url=https://sci-hub.do/10.1016/j. | |full-text-url=https://sci-hub.do/10.1016/j.biocel.2013.05.034 | ||
}} | }} | ||
== | ==BNIP3== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. | ||
|date= | |date=01.10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training. | ||
|date= | |date=01.10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030137 | ||
|full-text-url=https://sci-hub.do/10.1016/j.exger. | |full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.011 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effects of β-hydroxy-β-methylbutyrate on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults. | ||
|date= | |date=01.11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28705993 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1152/japplphysiol.00192.2017 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Akt2 ablation prolongs life span and improves myocardial contractile function with adaptive cardiac remodeling: role of Sirt1-mediated autophagy regulation. | ||
|date=10. | |date=10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28681509 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595687 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=In Brief: Mitophagy: mechanisms and role in human disease. | ||
|date= | |date=11.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27453450 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071152 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway. | ||
|date= | |date=01.08.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27334614 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969577 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Interfacing mitochondrial biogenesis and elimination to enhance host pathogen defense and longevity. | ||
|date= | |date=07-09.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26430570 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588546 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Coupling mitogenesis and mitophagy for longevity. | ||
|date= | |date=2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26083448 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590656 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Dying myofibers in elderly mouse skeletal muscles are characterized by the appearance of dystrophin-encircled vacuoles. | ||
|date= | |date=08.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25758773 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s10522-015-9565-0 | ||
}} | }} | ||
== | ==BPIFB4== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=New Insights for [[BPIFB4]] in Cardiovascular Therapy. | ||
|date= | |date=28.09.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32998388 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7583974 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=High TARC plasma levels confer protection to long living individuals by inducing M2 profile. | ||
|date= | |date=01.2021 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002742 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155305 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Circulating [[BPI]]FB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals. | ||
|date= | |date=2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32547549 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272600 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/[[CXCR4]] signalling pathway. | ||
|date= | |date=09.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32384208 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1002/ejhf.1840 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=LAV-[[BPIFB4]] associates with reduced frailty in humans and its transfer prevents frailty progression in old mice. | ||
|date= | |date=28.08.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31461407 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738439 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Longevity-Associated Variant of [[BPIFB4]] Mitigates Monocyte-Mediated Acquired Immune Response. | ||
|date= | |date=13.11.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074771 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1093/gerona/glz036 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of [[BPIFB4]]. | ||
|date= | |date=19.10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30347645 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214030 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The expression of the [[BPI]]FB4 and [[CXCR4]] associates with sustained health in long-living individuals from Cilento-Italy. | ||
|date= | |date=22.01.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121621 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361669 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis. | ||
|date= | |date=31.07.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26034043 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496930 | ||
}} | }} | ||
== | ==CCN1== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis. | ||
|date= | |date=09.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32651107 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.rbmo.2020.04.006 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Inhibition of cellular communication network factor 1 ([[CCN1]])-driven senescence slows down cartilage inflammaging and osteoarthritis. | ||
|date= | |date=10.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32622876 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115522 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[Aging of skin fibroblasts: genetic and epigenetic factors.] | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32160428 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The senescence-associated matricellular protein [[CCN1]] in plasma of human subjects with idiopathic pulmonary fibrosis. | ||
|date=2020 | |date=01.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765873 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023981 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[CCN1]] (CYR61) and [[CCN3]] (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties. | ||
|date= | |date=03.03.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26744771 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853050 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Aging increases [[CCN1]] expression leading to muscle senescence. | ||
|date= | |date=01.01.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24196529 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919975 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Impaired intervertebral disc development and premature disc degeneration in mice with notochord-specific deletion of [[CCN2]]. | ||
|date= | |date=10.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23839921 | ||
|full-text-url=https://sci-hub.do/10.1002/ | |full-text-url=https://sci-hub.do/10.1002/art.38075 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The matricellular protein [[CCN1]] suppresses lung cancer cell growth by inducing senescence via the p53/p21 pathway. | ||
|date= | |date=09.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23553737 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1002/jcb.24557 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Cysteine-rich protein 61 ([[CCN1]]) domain-specific stimulation of matrix metalloproteinase-1 expression through αVβ3 integrin in human skin fibroblasts. | ||
|date= | |date=26.04.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23504324 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636922 | ||
}} | }} | ||
== | ==CCR5== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The Puzzling Role of Neuron-Specific PMCA Isoforms in the Aging Process. | ||
|date= | |date=16.12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31888192 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941135 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[Enhancement can do harm]. | ||
|date= | |date=08-09.2019 | ||
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|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1051/medsci/2019136 | ||
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* {{medline-title | * {{medline-title | ||
|title= | |title=[[CCR5]]-∆32 is deleterious in the homozygous state in humans. | ||
|date= | |date=06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160814 | ||
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* {{medline-title | * {{medline-title | ||
|title= | |title=[[CCR5]] chemokine receptor gene polymorphisms in ocular toxoplasmosis. | ||
|date= | |date=02.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29221851 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.actatropica.2017.12.012 | ||
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* {{medline-title | * {{medline-title | ||
|title= | |title=Peripheral loss of CD8( ) CD161( ) TCRVα7·2( ) mucosal-associated invariant T cells in chronic hepatitis C virus-infected patients. | ||
|date= | |date=02.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26681320 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1111/eci.12581 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Increased susceptibility of [[CD4]] T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced [[CD4]] and enhanced [[CXCR4]] and [[FAS]] surface expression levels. | ||
|date= | |date=09.10.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26452480 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600300 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Aging-associated subpopulations of human CD8 T-lymphocytes identified by their [[CD28]] and CD57 phenotypes. | ||
|date= | |date=11-12.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26277688 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.archger.2015.08.007 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Cutting edge: Central memory CD8 T cells in aged mice are virtual memory cells. | ||
|date= | |date=15.12.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24227783 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858473 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[[CCR5]], [[CCR2]], apoe, p53, [[ITGB3]] and [[HFE]] gene polymorphism in Western Siberia long-livers]. | ||
|date= | |date=2012 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23289212 | ||
}} | }} | ||
== | ==CDA== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Cumulative Dis/Advantage and Health Pattern in Late Life: A Comparison between Genders and Welfare State Regimes. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771483 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367435 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Does numerical similarity alter age-related distractibility in working memory? | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31483830 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726243 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Can working memory capacity be expanded by boosting working memory updating efficiency in older adults? | ||
|date= | |date=12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30475011 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1037/pag0000311 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Negative Affect Influences Electrophysiological Markers of Visual Working Memory in Mildly Stressed Older Adults. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29872391 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972212 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development. | ||
|date=02. | |date=02.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175710 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2017.10.018 | ||
}} | |||
* {{medline-title | |||
|title=Mini dental assessment: a simple screening test for non-dental staff. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27401181 | |||
|full-text-url=https://sci-hub.do/10.1007/s00784-016-1906-0 | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Electrophysiological Correlates of Subitizing in Healthy Aging. | ||
|date= | |date=2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26098959 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476746 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Understanding age-related reductions in visual working memory capacity: examining the stages of change detection. | ||
|date= | |date=10.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24420648 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098047 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Retrospective attention enhances visual working memory in the young but not the old: an ERP study. | ||
|date= | |date=05.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23445536 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618566 | ||
}} | }} | ||
== | ==CTCF== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=New targeted approaches for epigenetic age predictions. | ||
|date= | |date=24.06.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32580727 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315536 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Blood DNA Methylation and Aging: A Cross-Sectional Analysis and Longitudinal Validation in the InCHIANTI Study. | ||
|date= | |date=15.10.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32147700 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566335 | ||
}} | |||
* {{medline-title | |||
|title=In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520345 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09834-1 | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765957 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938407 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[HMGB2]] Loss upon Senescence Entry Disrupts Genomic Organization and Induces [[CTCF]] Clustering across Cell Types. | ||
|date= | |date=17.05.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706538 | ||
|full-text-url=https://sci-hub.do/10.1016/j. | |full-text-url=https://sci-hub.do/10.1016/j.molcel.2018.03.030 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes. | ||
|date= | |date=2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25880792 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623031 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape. | ||
|date= | |date=2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24034465 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053985 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Chromatin remodeling of human subtelomeres and TERRA promoters upon cellular senescence: commonalities and differences between chromosomes. | ||
|date= | |date=05.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23644601 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741221 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. | ||
|date= | |date=07.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23580197 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701217 | ||
}} | }} | ||
== | ==CXCL2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. | ||
|date= | |date=2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33041998 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525127 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182922 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535784 | ||
}} | |||
* {{medline-title | |||
|title=Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice. | |||
|date=02.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31048563 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535057 | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. | ||
|date= | |date=19.02.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30709741 | ||
|full-text-url=https://sci-hub.do/10.1016/j. | |full-text-url=https://sci-hub.do/10.1016/j.immuni.2019.01.002 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality. | ||
|date= | |date=03.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30617300 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375784 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles. | ||
|date= | |date=05.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1620/tjem.245.29 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Tumor microenvironment in functional adrenocortical adenomas: immune cell infiltration in cortisol-producing adrenocortical adenoma. | ||
|date= | |date=07.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596893 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.humpath.2018.03.016 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. | ||
|date= | |date=02.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27845246 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.bbalip.2016.11.003 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Mice with heterozygous deficiency of manganese superoxide dismutase ([[SOD2]]) have a skin immune system with features of "inflamm-aging". | ||
|date= | |date=03.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23856836 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s00403-013-1389-7 | ||
}} | }} | ||
== | ==DBI== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Quantifying cumulative anticholinergic and sedative drug load among US Medicare Beneficiaries. | ||
|date= | |date=01.10.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33000867 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1002/pds.5144 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Drug Burden Index and Cognitive and Physical Function in Aged Care Residents: A Longitudinal Study. | ||
|date= | |date=08.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736845 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.jamda.2020.05.037 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Using the Drug Burden Index to identify older adults at highest risk for medication-related falls. | ||
|date= | |date=12.06.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32532276 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291506 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Impact of STEADI-Rx: A Community Pharmacy-Based Fall Prevention Intervention. | ||
|date= | |date=08.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32315461 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1111/jgs.16459 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Association of Drug Burden Index with grip strength, timed up and go and Barthel index activities of daily living in older adults with intellectual disabilities: an observational cross-sectional study. | ||
|date= | |date=24.06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31234775 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591943 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Impact of drug burden index on adverse health outcomes in Irish community-dwelling older people: a cohort study. | ||
|date= | |date=29.04.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31035946 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489229 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Dietary Balance Index-07 and the Risk of Anemia in Middle Aged and Elderly People in Southwest China: A Cross Sectional Study. | ||
|date= | |date=31.01.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29385057 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852738 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title=The | |title=Effects of Changes in Number of Medications and Drug Burden Index Exposure on Transitions Between Frailty States and Death: The Concord Health and Ageing in Men Project Cohort Study. | ||
|date= | |date=01.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26782856 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1111/jgs.13877 | ||
}} | |||
* {{medline-title | |||
|title=Drug Burden Index score and anticholinergic risk scale as predictors of readmission to the hospital. | |||
|date=03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589765 | |||
|full-text-url=https://sci-hub.do/10.4140/TCP.n.2014.158 | |||
}} | }} | ||
== | ==DES== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis. | ||
|date= | |date=20.03.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29558926 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859529 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Genetic variation in low-dose effects of neonatal [[DES]] exposure in female rats. | ||
|date= | |date=10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28734970 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.reprotox.2017.07.005 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Aging Eye Microbiota in Dry Eye Syndrome in Patients Treated with [i]Enterococcus faecium[/i] and [i]Saccharomyces boulardii[/i]. | ||
|date= | |date=2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676009 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.2174/1574884712666170704145046 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The influence of advancing age on implantation of drug-eluting stents. | ||
|date= | |date=10.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26603135 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1002/ccd.26333 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Calculating when elective abdominal aortic aneurysm repair improves survival for individual patients: development of the Aneurysm Repair Decision Aid and economic evaluation. | ||
|date= | |date=04.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25924187 | ||
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}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Diethylstilbestrol exposure in neonatal mice induces changes in the adulthood in the immune response to taenia crassiceps without modifications of parasite loads. | ||
|date= | |date=2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25243144 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163381 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Androgen deficiency and dry eye syndrome in the aging male. | ||
|date=07. | |date=03.07.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24994872 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132553 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[[DES]] Daughter--expertise remains necessary]. | ||
|date= | |date=2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24382040 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Emotional reactivity assessment of healthy elderly with an emotion-induction procedure. | ||
|date= | |date=2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23316739 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1080/0361073X.2013.741961 | ||
}} | }} | ||
==EDA== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=Interplay between aging, lung inflammation/remodeling, and fibronectin [[EDA]] in lung cancer progression. | ||
|date= | |date=01.12.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33222614 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1080/15384047.2020.1831372 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Arousal Detection in Elderly People from Electrodermal Activity Using Musical Stimuli. | ||
|date=2020 | |date=25.08.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32854302 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506973 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The structure of agricultural microplastics (PT, PU and UF) and their sorption capacities for PAHs and PHE derivates under various salinity and oxidation treatments. | ||
|date= | |date=02.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31761592 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.envpol.2019.113525 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of storage on quality parameters and phenolic content of Italian extra-virgin olive oils. | ||
|date= | |date=01.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30896291 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1080/14786419.2019.1587434 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice. | ||
|date= | |date=03.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326316 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823768 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=An Extract from the Plant [i]Deschampsia antarctica[/i] Protects Fibroblasts from Senescence Induced by Hydrogen Peroxide. | ||
|date= | |date=2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894504 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574316 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Occurrence of fibronectin-fibrin complexes in plasma of patients with multimorbidity due to the inflamm-aging phenomenon. | ||
|date= | |date=05.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26883337 | ||
|full-text-url=https://sci-hub.do/10.1016/j. | |full-text-url=https://sci-hub.do/10.1016/j.exger.2016.02.006 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy. | ||
|date= | |date=09.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26220387 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.eplepsyres.2015.06.005 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Error detection and error memory in spatial navigation as reflected by electrodermal activity. | ||
|date=11. | |date=11.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23700191 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s10339-013-0567-z | ||
}} | }} | ||
==FOXM1== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression. | ||
|date=10.2020 | |date=10.11.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33171439 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695388 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Upregulation of [[FOXM1]] leads to diminished drug sensitivity in myeloma. | ||
|date= | |date=21.11.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463534 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249818 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Preclinical characterization of abemaciclib in hormone receptor positive breast cancer. | ||
|date= | |date=19.09.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29050219 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642494 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. | ||
|date= | |date=02.10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[FOXM1]] regulates proliferation, senescence and oxidative stress in keratinocytes and cancer cells. | ||
|date= | |date=07.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27385468 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993337 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[MELK]]-T1, a small-molecule inhibitor of protein kinase [[MELK]], decreases DNA-damage tolerance in proliferating cancer cells. | ||
|date= | |date=02.10.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26431963 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643329 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Increased [[FOXM1]] expression can stimulate DNA repair in normal hepatocytes in vivo but also increases nuclear foci associated with senescence. | ||
|date= | |date=02.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25477198 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522743 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Cellular senescence and aging: the role of B-[[MYB]]. | ||
|date= | |date=10.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24981831 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331756 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=MiR-506 suppresses proliferation and induces senescence by directly targeting the [[CDK4]]/6-[[FOXM1]] axis in ovarian cancer. | ||
|date= | |date=07.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24604117 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144705 | ||
}} | }} | ||
==GAA== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia. | ||
|date=07 | |date=27.07.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32586831 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406325 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-Related Changes in Serum Guanidinoacetic Acid in Women. | ||
|date= | |date=30.12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31647299 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.33549/physiolres.934189 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. | ||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756 | |||
|date= | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | ||
|date= | |date=09.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age and gender-specific reference intervals for lysosomal enzymes in dried blood spot samples: A study in Indian population. | ||
|date= | |date=10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396248 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.clinbiochem.2017.04.004 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effects of guanidinoacetic acid diet supplementation on semen quality and fertility of broiler breeder roosters. | ||
|date=02. | |date=02.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28043349 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2016.11.012 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of feeding guanidinoacetic acid and L-arginine on the fertility rate and sperm penetration in the perivitelline layer of aged broiler breeder hens. | ||
|date= | |date=04.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26216477 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1111/jpn.12372 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease. | ||
|date=10. | |date=10.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26001726 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2015.05.019 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Dietary guanidino acetic acid is an efficacious replacement for arginine for young chicks. | ||
|date= | |date=01.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23243244 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.3382/ps.2012-02425 | ||
}} | }} | ||
==GK== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=Progression of diabetic kidney disease in T2DN rats. | ||
|date= | |date=01.12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566426 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960784 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging. | ||
|date= | |date=04.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30609251 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413652 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-Related Reduction of Contractile Responses to Urotensin II Is Seen in Aortas from Wistar Rats but Not from Type 2 Diabetic Goto-Kakizaki Rats. | ||
|date= | |date=04.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27841739 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1089/rej.2016.1864 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[STUDY RELATIVE EXPRESSION OF GENES THAT CONTROL GLUCOSE METABOLISM IN THE LIVER IN MICE WITH DEVELOPMENT OF MELANOCORTIN OBESITY]. | ||
|date= | |date=06.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26470488 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Delta Cell Hyperplasia in Adult Goto-Kakizaki ([[GK]]/MolTac) Diabetic Rats. | ||
|date= | |date=2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26236746 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506919 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes. | ||
|date= | |date=2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25182811 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.2174/1567202611666140903122801 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Evidence for cortical neuronal loss in male type 2 diabetic Goto-Kakizaki rats. | ||
|date= | |date=2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24643136 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.3233/JAD-131958 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Dietary resistant starch improves selected brain and behavioral functions in adult and aged rodents. | ||
|date= | |date=11.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23818307 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892668 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Decreased glucokinase protein expression in the aged gerbil hippocampus. | ||
|date= | |date=05.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23515967 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s10571-013-9928-5 | ||
}} | }} | ||
==HDAC2== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=EEF1A1 deacetylation enables transcriptional activation of remyelination. | ||
|date= | |date=09.07.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32647127 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347577 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16 . | ||
|date= | |date=06.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790400 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516428 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. | ||
|date=04. | |date=04.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30659954 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.exger.2019.01.016 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[HDAC3]] Regulates the Transition to the Homeostatic Myelinating Schwann Cell State. | ||
|date= | |date=04.12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30517863 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293966 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Altered modulation of lamin A/C-[[HDAC2]] interaction and p21 expression during oxidative stress response in HGPS. | ||
|date= | |date=10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30109767 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156291 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri. | ||
|date=09. | |date=09.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Histone Deacetylase 2 Inhibition Attenuates Downregulation of Hippocampal Plasticity Gene Expression during Aging. | ||
|date= | |date=03.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28364391 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s12035-017-0490-x | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Non-sirtuin histone deacetylases in the control of cardiac aging. | ||
|date= | |date=06.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25791169 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459895 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Histone deacetylase 2 in the mouse hippocampus: attenuation of age-related increase by caloric restriction. | ||
|date= | |date=10.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24093534 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966721 | ||
}} | }} | ||
== | ==IDH2== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Oxidative Damage to the TCA Cycle Enzyme [[MDH1]] Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. | ||
|date= | |date=03.04.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32175745 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00861 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions. | ||
|date= | |date=10.09.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31503005 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756887 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Augmentation of cellular NAD by [[NQO1]] enzymatic action improves age-related hearing impairment. | ||
|date= | |date=10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31353811 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718544 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Improving Treatment for Myelodysplastic Syndromes Patients. | ||
|date=10. | |date=25.10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362079 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s11864-018-0583-4 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Loss of [[IDH2]] Accelerates Age-related Hearing Loss in Male Mice. | ||
|date= | |date=22.03.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567975 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864918 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title=[ | |title=[[IDH2]]-deficient mice develop spinal deformities with aging. | ||
|date= | |date=17.07.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29527922 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.33549/physiolres.933711 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Idh2 deficiency accelerates renal dysfunction in aged mice. | ||
|date= | |date=04.11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928092 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.082 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[IDH1]] Associated with Neuronal Apoptosis in Adult Rats Brain Following Intracerebral Hemorrhage. | ||
|date= | |date=07.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27568302 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/s10571-016-0421-9 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Epigenetic Aging Signatures Are Coherently Modified in Cancer. | ||
|date= | |date=06.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26110659 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482318 | ||
}} | }} | ||
==IDS== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of immediate dentine sealing on the aging and fracture strength of lithium disilicate inlays and overlays. | ||
|date= | |date=10.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32957211 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2020.103906 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Increased double limb support times during walking in right limb dominant healthy older adults with low bone density. | ||
|date= | |date=06.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730490 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.gaitpost.2018.04.036 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Comparison of two automated assays of BTM (CTX and P1NP) and reference intervals in a Danish population. | ||
|date= | |date=07.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28455749 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/s00198-017-4026-z | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Metabolic dysregulation and late-life depression: a prospective study. | ||
|date= | |date=04.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27938429 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1017/S0033291716003196 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Total tooth loss and complete denture use in older adults with intellectual disabilities in Ireland. | ||
|date= | |date=Spring.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25318359 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1111/jphd.12077 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Depression in later life: a more somatic presentation? | ||
|date= | |date=01.01.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25254617 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.jad.2014.08.032 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Reference intervals for insulin-like growth factor-1 (igf-i) from birth to senescence: results from a multicenter study using a new automated chemiluminescence IGF-I immunoassay conforming to recent international recommendations. | ||
|date= | |date=05.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24606072 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1210/jc.2013-3059 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age- and sex-specific reference intervals across life span for insulin-like growth factor binding protein 3 (IGFBP-3) and the IGF-I to IGFBP-3 ratio measured by new automated chemiluminescence assays. | ||
|date= | |date=05.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24483154 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1210/jc.2013-3060 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Transcriptomics of cortical gray matter thickness decline during normal aging. | ||
|date= | |date=15.11.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23707588 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759649 | ||
}} | }} | ||
==ILK== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=Concurrent nicotine exposure to prenatal alcohol consumption alters the hippocampal and cortical neurotoxicity. | ||
|date= | |date=01.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31938742 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953639 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy. | ||
|date= | |date=01.04.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30605403 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485685 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia. | ||
|date= | |date=10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30271655 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147593 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Integrin-linked kinase: A new actor in the ageing process? | ||
|date= | |date=15.12.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101014 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.exger.2017.10.026 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Hyperphosphatemia induces cellular senescence in human aorta smooth muscle cells through integrin linked kinase ([[ILK]]) up-regulation. | ||
|date= | |date=12.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26467393 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.mad.2015.10.001 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Integrin-linked kinase regulates senescence in an Rb-dependent manner in cancer cell lines. | ||
|date= | |date=2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26176204 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825635 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. | ||
|date= | |date=06.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24400780 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032615 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1. | ||
|date= | |date=06.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24314125 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059541 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=PPARβ/δ promotes [[HRAS]]-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling. | ||
|date= | |date=13.11.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24213576 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017002 | ||
}} | }} | ||
==LAMP1== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=Resemblance and differences in dietary restriction nephroprotective mechanisms in young and old rats. | ||
|date= | |date=24.09.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32970613 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585108 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into [[RPE]] Stress Associated with Retinopathy. | ||
|date= | |date=11.09.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932802 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555953 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain. | ||
|date= | |date=24.06.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32579115 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367682 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Yishen Huazhuo Decoction Induces Autophagy to Promote the Clearance of Aβ<sub>1-42</sub> in SAMP8 Mice: Mechanism Research of a Traditional Chinese Formula Against Alzheimer's Disease. | ||
|date=2020 | |date=2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32496993 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.2174/1871527319666200604174223 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Dysregulations of mitochondrial quality control and autophagic flux at an early age lead to progression of sarcopenia in SAMP8 mice. | ||
|date= | |date=06.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32130580 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1007/s10522-020-09867-x | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Deacetylation of [[LAMP1]] drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. | ||
|date= | |date=03.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31544977 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1002/jcp.29182 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A pH probe inhibits senescence in mesenchymal stem cells. | ||
|date= | |date=07.12.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. | ||
|date= | |date=01.10.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease). | ||
|date= | |date=15.12.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26450516 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654058 | ||
}} | }} | ||
== | ==LSS== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Surgical results in older patients with lumbar spinal stenosis according to gait speed in relation to the diagnosis for sarcopenia. | ||
|date= | |date=01-04.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32329390 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1177/2309499020918422 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Streamlining an existing hip fracture patient pathway in an acute tertiary adult Irish hospital to improve patient experience and outcomes. | ||
|date= | |date=22.12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31867664 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926383 | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title=A | |title=Low-dose radiation from A-bombs elongated lifespan and reduced cancer mortality relative to un-irradiated individuals. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30598710 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299535 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Lung, Laryngeal and Other Respiratory Cancer Incidence among Japanese Atomic Bomb Survivors: An Updated Analysis from 1958 through 2009. | ||
|date= | |date=05.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28323575 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505071 | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Quantitating the lateral skin stiffness by a new and versatile electro-mechanical instrument. Preliminary studies. | ||
|date= | |date=08.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27896851 | ||
|full-text-url=https://sci-hub.do/10.1111/srt.12331 | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A message to Fukushima: nothing to fear but fear itself. | ||
|date= | |date=2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27350831 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918197 | |||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Exposure to ionizing radiation and brain cancer incidence: The Life Span Study cohort. | ||
|date= | |date=06.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27038588 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1016/j.canep.2016.03.006 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Lumbar spondylosis, lumbar spinal stenosis, knee pain, back muscle strength are associated with the locomotive syndrome: Rural population study in Japan. | ||
|date= | |date=05.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27021251 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.jos.2016.02.006 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Does Obesity Affect Outcomes After Decompressive Surgery for Lumbar Spinal Stenosis? A Multicenter, Observational, Registry-Based Study. | ||
|date= | |date=11.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26100169 | ||
|full-text-url=https://sci-hub.do/10.1016/j. | |full-text-url=https://sci-hub.do/10.1016/j.wneu.2015.06.020 | ||
}} | }} | ||
==MFI== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=The Influence of the Accelerated Aging Conditions on the Properties of Polyolefin Geogrids Used for Landfill Slope Reinforcement. | ||
|date= | |date=20.08.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32825284 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564637 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Changes in Physical Meat Traits, Protein Solubility, and the Microstructure of Different Beef Muscles during Post-Mortem Aging. | ||
|date= | |date=19.06.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32575353 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353465 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Effect of a low-voltage electrical stimulation on yak meat tenderness during postmortem aging. | ||
|date=01 | |date=01-12.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32583539 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1111/asj.13410 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Comparative effects of dry-aging and wet-aging on physicochemical properties and digestibility of Hanwoo beef. | ||
|date= | |date=03.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31480178 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054618 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Sexual dimorphism in rat thymic involution: a correlation with thymic oxidative status and inflammation. | ||
|date= | |date=08.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31119497 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1007/s10522-019-09816-3 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Circulating soluble RAGE and cell surface RAGE on peripheral blood mononuclear cells in healthy children. | ||
|date= | |date=27.06.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29723156 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1515/jpem-2017-0512 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The frail fail: Increased mortality and post-operative complications in orthopaedic trauma patients. | ||
|date= | |date=11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888718 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.injury.2017.08.026 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Meat quality attributes of Agile Wallabies. | ||
|date= | |date=11.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28697421 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.meatsci.2017.06.016 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Phagocyte dysfunction in polymyalgia rheumatica and other age-related, chronic, inflammatory conditions. | ||
|date= | |date=11.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23904438 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1189/jlb.0113034 | ||
}} | }} | ||
== | ==MIA== | ||
* {{medline-title | * {{medline-title | ||
|title=[ | |title=[[TP53]]/miR-34a-associated signaling targets [i]SERPINE1[/i] expression in human pancreatic cancer. | ||
|date= | |date=27.01.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31986125 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041729 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age, cohort, and period effects on metamemory beliefs. | ||
|date= | |date=12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31804113 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901096 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Memory Age-based Stereotype Threat: Role of Locus of Control and Anxiety. | ||
|date= | |date=01-02.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31752597 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.1080/0361073X.2019.1693009 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice. | ||
|date= | |date=27.09.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31569601 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801581 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Role of melanoma inhibitory activity in melanocyte senescence. | ||
|date= | |date=11.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31172672 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1111/pcmr.12801 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Refining the metamemory in adulthood questionnaire: a 20-item version of change and capacity designed for research and clinical settings. | ||
|date= | |date=07.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30957531 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779492 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Maternal Immune Activation Alters Adult Behavior, Gut Microbiome and Juvenile Brain Oscillations in Ferrets. | ||
|date= | |date=09-10.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30406186 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220580 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Differential proteomic and oxidative profiles unveil dysfunctional protein import to adipocyte mitochondria in obesity-associated aging and diabetes. | ||
|date= | |date=04.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28064117 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220168 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice. | ||
|date= | |date=06.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25971876 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430498 | ||
}} | }} | ||
==MMD== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study. | ||
|date= | |date=22.11.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33266358 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7700674 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study. | ||
|date= | |date=16.09.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32947839 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564216 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Impact and Lessons From the Lifestyle Interventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability. | ||
|date= | |date=04.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105353 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187344 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Lactobacillus rescues postnatal neurobehavioral and microglial dysfunction in a model of maternal microbiome dysbiosis. | ||
|date= | |date=10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31351186 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.bbi.2019.07.025 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=A Case for Promoting Movement Medicine: Preventing Disability in the LIFE Randomized Controlled Trial. | ||
|date= | |date=04.10.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30778518 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777081 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Determinants of Basal Collaterals in Moyamoya Disease: Clinical and Genetic Factors. | ||
|date= | |date=2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27046023 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1159/000445348 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Antihypertensive Use and the Effect of a Physical Activity Intervention in the Prevention of Major Mobility Disability Among Older Adults: The LIFE Study. | ||
|date= | |date=07.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26865496 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906322 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Perfusion characteristics of Moyamoya disease: an anatomically and clinically oriented analysis and comparison. | ||
|date= | |date=01.2014 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24193795 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1161/STROKEAHA.113.003370 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Do older patients find multi-compartment medication devices easy to use and which are the easiest? | ||
|date= | |date=11.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23978406 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1093/ageing/aft113 | ||
}} | }} | ||
== | ==MRE11== | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[TPP1]] Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the [[MRE11]]/AKT Pathway. | ||
|date= | |date=2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33195247 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658181 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Chromosomal alterations among age-related haematopoietic clones in Japan. | ||
|date= | |date=08.2020 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32581364 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489641 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=[[ATM]] Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781094 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856652 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. | ||
|date= | |date=2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. | ||
|date= | |date=2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells. | ||
|date= | |date=01.09.2018 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775409 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172637 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries. | ||
|date= | |date=03.04.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552356 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1080/10495398.2016.1210613 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=NBS1 is required for macrophage homeostasis and functional activity in mice. | ||
|date= | |date=26.11.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26324700 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1182/blood-2015-04-637371 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Impairment of [[BRCA1]]-related DNA double-strand break repair leads to ovarian aging in mice and humans. | ||
|date= | |date=13.02.2013 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23408054 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130338 | ||
}} | }} | ||
==MSTN== | |||
* {{medline-title | * {{medline-title | ||
|title= | |title=Age- and stage-dependent variations of muscle-specific gene expression in brown trout Salmo trutta L. | ||
|date= | |date=09.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28408166 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1016/j.cbpb.2017.04.001 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Activity of metabolic enzymes and muscle-specific gene expression in parr and smolts Atlantic salmon Salmo salar L. of different age groups. | ||
|date= | |date=08.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28315163 | ||
|full-text-url=https://sci-hub.do/10.1007/ | |full-text-url=https://sci-hub.do/10.1007/s10695-017-0357-0 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=miR-30e is negatively regulated by myostatin in skeletal muscle and is functionally related to fiber-type composition. | ||
|date= | |date=01.05.2017 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28338991 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1093/abbs/gmx019 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Muscle-Related Polymorphisms ([[MSTN]] rs1805086 and [[ACTN3]] rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians. | ||
|date= | |date=2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27861536 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115755 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Temporal and spatial expression of Smads and their correlation with [[YAP1]] expression in sheep. | ||
|date= | |date=26.08.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27706608 | ||
|full-text-url=https://sci-hub.do/10. | |full-text-url=https://sci-hub.do/10.4238/gmr.15037715 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Quantification of [[GDF11]] and Myostatin in Human Aging and Cardiovascular Disease. | ||
|date=06. | |date=14.06.2016 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27304512 | ||
|full-text-url=https:// | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913514 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Morphological analysis and muscle-associated gene expression during different muscle growth phases of Megalobrama amblycephala. | ||
|date= | |date=28.09.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26436405 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.4238/2015.September.28.16 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=The effect of exercise mode on the acute response of satellite cells in old men. | ||
|date= | |date=12.2015 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26367861 | ||
|full-text-url=https:// | |full-text-url=https://sci-hub.do/10.1111/apha.12601 | ||
}} | }} | ||
* {{medline-title | * {{medline-title | ||
|title= | |title=Association of the K153R polymorphism in the myostatin gene and extreme longevity. | ||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23354683 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825013 | |||
}} | |||
==PNN== | |||
* {{medline-title | |||
|title=Hyaluronan degradation and release of a hyaluronan-aggrecan complex from perineuronal nets in the aged mouse brain. | |||
|date=28.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33253804 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbagen.2020.129804 | |||
}} | |||
* {{medline-title | |||
|title=Maturation of [[PNN]] and ErbB4 Signaling in Area [[CA2]] during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory. | |||
|date=29.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665627 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.09.044 | |||
}} | |||
* {{medline-title | |||
|title=Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706367 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-019-1499-0 | |||
}} | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent and region-specific alteration of parvalbumin neurons and perineuronal nets in the mouse cerebral cortex. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29126935 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2017.11.001 | |||
}} | |||
* {{medline-title | |||
|title=Brain ageing changes proteoglycan sulfation, rendering perineuronal nets more inhibitory. | |||
|date=28.06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28657900 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509459 | |||
}} | |||
* {{medline-title | |||
|title=Removal of Perineuronal Nets Unlocks Juvenile Plasticity Through Network Mechanisms of Decreased Inhibition and Increased Gamma Activity. | |||
|date=01.02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039374 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596863 | |||
}} | |||
* {{medline-title | |||
|title=Age-Related Deterioration of Perineuronal Nets in the Primary Auditory Cortex of Mice. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27877127 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099154 | |||
}} | |||
* {{medline-title | |||
|title=Spatio-temporal differences in perineuronal net expression in the mouse hippocampus, with reference to parvalbumin. | |||
|date=03.12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24016683 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2013.08.061 | |||
}} | |||
==POLG== | |||
* {{medline-title | |||
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. | |||
|date=08.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209 | |||
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054 | |||
}} | |||
* {{medline-title | |||
|title=Parkin does not prevent accelerated cardiac aging in mitochondrial DNA mutator mice. | |||
|date=16.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30990467 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542612 | |||
}} | |||
* {{medline-title | |||
|title=The effects of AICAR and rapamycin on mitochondrial function in immortalized mitochondrial DNA mutator murine embryonic fibroblasts. | |||
|date=16.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30177551 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262855 | |||
}} | |||
* {{medline-title | |||
|title=Impact of exercise on oocyte quality in the [[POLG]] mitochondrial DNA mutator mouse. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875308 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6074767 | |||
}} | |||
* {{medline-title | |||
|title=The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways. | |||
|date=08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28499253 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429232 | |||
}} | |||
* {{medline-title | |||
|title=Metabolomic analysis of exercise effects in the [[POLG]] mitochondrial DNA mutator mouse brain. | |||
|date=11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26294258 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609600 | |||
}} | |||
* {{medline-title | |||
|title=Mitochondria DNA mutations cause sex-dependent development of hypertension and alterations in cardiovascular function. | |||
|date=05.02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25582357 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306604 | |||
}} | |||
* {{medline-title | |||
|title=Somatic mitochondrial DNA mutations do not increase neuronal vulnerability to MPTP in young [[POLG]] mutator mice. | |||
|date=11-12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25450660 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293310 | |||
}} | |||
* {{medline-title | |||
|title=The impact of pathogenic mitochondrial DNA mutations on substantia nigra neurons. | |||
|date=26.06.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23804100 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6618501 | |||
}} | |||
==RAD51== | |||
* {{medline-title | |||
|title=53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. | |||
|date=02.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653568 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993210 | |||
}} | |||
* {{medline-title | |||
|title=Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. | |||
|date=09.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31291576 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.06.043 | |||
}} | |||
* {{medline-title | |||
|title=Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae. | |||
|date=01.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075257 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563841 | |||
}} | |||
* {{medline-title | |||
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287 | |||
}} | |||
* {{medline-title | |||
|title=The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30235328 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147527 | |||
}} | |||
* {{medline-title | |||
|title=Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence. | |||
|date=11.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27626497 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341871 | |||
}} | |||
* {{medline-title | |||
|title=BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries. | |||
|date=03.04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27552356 | |||
|full-text-url=https://sci-hub.do/10.1080/10495398.2016.1210613 | |||
}} | |||
* {{medline-title | |||
|title=[[SQSTM1]]/p62 mediates crosstalk between autophagy and the UPS in DNA repair. | |||
|date=02.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391408 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391493 | |||
}} | |||
* {{medline-title | |||
|title=[[RECQL5]] has unique strand annealing properties relative to the other human RecQ helicase proteins. | |||
|date=01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26717024 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903426 | |||
}} | |||
==SMAD2== | |||
* {{medline-title | |||
|title=Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging. | |||
|date=18.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33217999 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7698786 | |||
}} | |||
* {{medline-title | |||
|title=The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32717457 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jphotobiol.2020.111964 | |||
}} | |||
* {{medline-title | |||
|title=Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31674011 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071816 | |||
}} | |||
* {{medline-title | |||
|title=Restoring extracellular matrix synthesis in senescent stem cells. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287964 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766659 | |||
}} | |||
* {{medline-title | |||
|title=iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation. | |||
|date=01.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708522 | |||
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.06.014 | |||
}} | |||
* {{medline-title | |||
|title=Exogenous [[GDF11]] induces cardiac and skeletal muscle dysfunction and wasting. | |||
|date=07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28647906 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833306 | |||
}} | |||
* {{medline-title | |||
|title=Circulating Growth Differentiation Factor 11/8 Levels Decline With Age. | |||
|date=08.01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26489925 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748736 | |||
}} | |||
* {{medline-title | |||
|title=Effects of aging on cardiac extracellular matrix in men and women. | |||
|date=01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26280680 | |||
|full-text-url=https://sci-hub.do/10.1002/prca.201500031 | |||
}} | |||
* {{medline-title | |||
|title=Age-associated changes in gene expression of goat oocytes. | |||
|date=01.09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23746875 | |||
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2013.04.019 | |||
}} | |||
==SON== | |||
* {{medline-title | |||
|title=Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha. | |||
|date=01.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30861131 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656591 | |||
}} | |||
* {{medline-title | |||
|title=Neural Mechanisms Involved in the Noxious Physical Stress-Induced Inhibition of Ovarian Estradiol Secretion. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30730610 | |||
|full-text-url=https://sci-hub.do/10.1002/ar.24078 | |||
}} | |||
* {{medline-title | |||
|title=Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518407 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019141 | |||
}} | |||
* {{medline-title | |||
|title=The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29494864 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878011 | |||
}} | |||
* {{medline-title | |||
|title=Increased oxytocin-monomeric red fluorescent protein 1 fluorescent intensity with urocortin-like immunoreactivity in the hypothalamo-neurohypophysial system of aged transgenic rats. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28859972 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neures.2017.08.001 | |||
}} | |||
* {{medline-title | |||
|title=Age-Related (Aged vs. Adult) Comparison of the Effect of Two Mild Stressors on the Nerve Growth Factor ([[NGF]]) in the Rat Hypothalamic Supraoptic Nucleus ([[SON]]) - Immunohistochemical Study. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27978417 | |||
}} | |||
* {{medline-title | |||
|title=Exposure to mild stress and brain derived neurotrophin factor ([[BDNF]]) immunoreactivity in the hypothalamic paraventricular (PVN) and supraoptic ([[SON]]) nuclei: Comparison between aged and adult rats. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27565677 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2016.08.007 | |||
}} | |||
* {{medline-title | |||
|title=Testing the critical window of estradiol replacement on gene expression of vasopressin, oxytocin, and their receptors, in the hypothalamus of aging female rats. | |||
|date=05.01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26454088 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684429 | |||
}} | |||
* {{medline-title | |||
|title=[Lamellar complex changes in the human basal forebrain and hypothalamic nuclei neurons in different age groups]. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25946833 | |||
}} | |||
==SQSTM1== | |||
* {{medline-title | |||
|title=The selective autophagy receptor [[SQSTM1]]/p62 improves lifespan and proteostasis in an evolutionarily conserved manner. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041473 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138197 | |||
}} | |||
* {{medline-title | |||
|title=[[SQSTM1]]/p62 and [[PPARGC1A]]/PGC-1alpha at the interface of autophagy and vascular senescence. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441382 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469683 | |||
}} | |||
* {{medline-title | |||
|title=[[SIRT2]] functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes. | |||
|date=01.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31295472 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116639 | |||
}} | |||
* {{medline-title | |||
|title=A pH probe inhibits senescence in mesenchymal stem cells. | |||
|date=07.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523 | |||
}} | |||
* {{medline-title | |||
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875 | |||
}} | |||
* {{medline-title | |||
|title=Systemic overexpression of [[SQSTM1]]/p62 accelerates disease onset in a [[SOD1]] -expressing ALS mouse model. | |||
|date=29.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843805 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975400 | |||
}} | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
* {{medline-title | |||
|title=[[SQSTM1]]/p62 mediates crosstalk between autophagy and the UPS in DNA repair. | |||
|date=02.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27391408 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391493 | |||
}} | |||
* {{medline-title | |||
|title=Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. | |||
|date=02.11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391655 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824610 | |||
}} | |||
==VHL== | |||
* {{medline-title | |||
|title=Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a [[VHL]]-1-independent transcriptional response. | |||
|date=12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399915 | |||
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00194-0 | |||
}} | |||
* {{medline-title | |||
|title=The Energy Maintenance Theory of Aging: Maintaining Energy Metabolism to Allow Longevity. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29901833 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314662 | |||
}} | |||
* {{medline-title | |||
|title=Shorter telomere length increases age-related tumor risks in von Hippel-Lindau disease patients. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28776935 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603836 | |||
}} | |||
* {{medline-title | |||
|title=Biological and clinical impact of hemangioblastoma-associated peritumoral cysts in von Hippel-Lindau disease. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26517769 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818154 | |||
}} | |||
* {{medline-title | |||
|title=Long-term prognosis of patients with pediatric pheochromocytoma. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24169644 | |||
|full-text-url=https://sci-hub.do/10.1530/ERC-13-0415 | |||
}} | |||
* {{medline-title | |||
|title=Inactivation of Vhl in osteochondral progenitor cells causes high bone mass phenotype and protects against age-related bone loss in adult mice. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23999831 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111233 | |||
}} | |||
* {{medline-title | |||
|title=Senescence-associated protein p400 is a prognostic marker in renal cell carcinoma. | |||
|date=11.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23982490 | |||
|full-text-url=https://sci-hub.do/10.3892/or.2013.2698 | |||
}} | |||
* {{medline-title | |||
|title=[[E2F1]] in renal cancer: Mr Hyde disguised as Dr Jekyll? | |||
|date=10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23868058 | |||
|full-text-url=https://sci-hub.do/10.1002/path.4238 | |||
}} | |||
* {{medline-title | |||
|title=Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner. | |||
|date=08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23566034 | |||
|full-text-url=https://sci-hub.do/10.1111/acel.12081 | |||
}} | |||
==VWF== | |||
* {{medline-title | |||
|title=Von Willebrand disease in the elderly: clinical perspectives. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30214173 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124462 | |||
}} | |||
* {{medline-title | |||
|title=Comorbidities associated with higher von Willebrand factor ([[VWF]]) levels may explain the age-related increase of [[VWF]] in von Willebrand disease. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29767844 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032952 | |||
}} | |||
* {{medline-title | |||
|title=The Association of Aging With Von Willebrand Factor Levels and Bleeding Risk in Type 1 Von Willebrand Disease. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28874064 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714664 | |||
}} | |||
* {{medline-title | |||
|title=Aging and [[ABO]] blood type influence von Willebrand factor and factor VIII levels through interrelated mechanisms. | |||
|date=05.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26875505 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949873 | |||
}} | |||
* {{medline-title | |||
|title=Age-related changes in platelet function are more profound in women than in men. | |||
|date=16.07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26179119 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503960 | |||
}} | |||
* {{medline-title | |||
|title=Von Willebrand factor and aging. | |||
|date=09.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25151524 | |||
|full-text-url=https://sci-hub.do/10.1055/s-0034-1389079 | |||
}} | |||
* {{medline-title | |||
|title=Aging hemostasis: changes to laboratory markers of hemostasis as we age - a narrative review. | |||
|date=09.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25099191 | |||
|full-text-url=https://sci-hub.do/10.1055/s-0034-1384631 | |||
}} | |||
* {{medline-title | |||
|title=von Willebrand disease and aging: an evolving phenotype. | |||
|date=07.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24750783 | |||
|full-text-url=https://sci-hub.do/10.1111/jth.12586 | |||
}} | |||
* {{medline-title | |||
|title=Age-related changes in aortic valve hemostatic protein regulation. | |||
|date=01.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24177329 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685477 | |||
}} | |||
==XIAP== | |||
* {{medline-title | |||
|title=Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and [[XIAP]]. | |||
|date=01.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.05.017 | |||
}} | |||
* {{medline-title | |||
|title=Modulated electro-hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31183995 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675742 | |||
}} | |||
* {{medline-title | |||
|title=Protective effect of xanthohumol against age-related brain damage. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011 | |||
}} | |||
* {{medline-title | |||
|title=Molecular modeling in the age of clinical genomics, the enterprise of the next generation. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28204942 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529140 | |||
}} | |||
* {{medline-title | |||
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044 | |||
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6 | |||
}} | |||
* {{medline-title | |||
|title=[[XIAP]]-associating factor 1, a transcriptional target of [[BRD7]], contributes to endothelial cell senescence. | |||
|date=02.02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26802028 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868675 | |||
}} | |||
* {{medline-title | |||
|title=Targeting protein neddylation with an [[NEDD8]]-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782162 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623239 | |||
}} | |||
* {{medline-title | |||
|title=Increase in retinal ganglion cells' susceptibility to elevated intraocular pressure and impairment of their endogenous neuroprotective mechanism by age. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24146536 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783363 | |||
}} | |||
* {{medline-title | |||
|title=The member of high temperature requirement family HtrA2 participates in neuronal apoptosis after intracerebral hemorrhage in adult rats. | |||
|date=08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23413020 | |||
|full-text-url=https://sci-hub.do/10.1007/s10735-013-9489-4 | |||
}} | |||
==YAP1== | |||
* {{medline-title | |||
|title=Loss of Wasl improves pancreatic cancer outcome. | |||
|date=21.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434991 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259520 | |||
}} | |||
* {{medline-title | |||
|title=Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. | |||
|date=13.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31935369 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146079 | |||
}} | |||
* {{medline-title | |||
|title=Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through [[YAP1]]. | |||
|date=05.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31487690 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756888 | |||
}} | |||
* {{medline-title | |||
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. | |||
|date=25.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331 | |||
}} | |||
* {{medline-title | |||
|title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607 | |||
}} | |||
* {{medline-title | |||
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827 | |||
}} | |||
* {{medline-title | |||
|title=Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases [[MST1]] and MST2. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27940445 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210079 | |||
}} | |||
* {{medline-title | |||
|title=Temporal and spatial expression of Smads and their correlation with [[YAP1]] expression in sheep. | |||
|date=26.08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27706608 | |||
|full-text-url=https://sci-hub.do/10.4238/gmr.15037715 | |||
}} | |||
* {{medline-title | |||
|title=Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. | |||
|date=29.09.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416764 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598835 | |||
}} | |||
==ABCA1== | |||
* {{medline-title | |||
|title=Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension. | |||
|date=01.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109455 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.08.027 | |||
}} | |||
* {{medline-title | |||
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770 | |||
}} | |||
* {{medline-title | |||
|title=Advanced glycation end products affect cholesterol homeostasis by impairing [[ABCA1]] expression on macrophages. | |||
|date=08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28704619 | |||
|full-text-url=https://sci-hub.do/10.1139/cjpp-2017-0170 | |||
}} | |||
* {{medline-title | |||
|title=Genome-wide DNA methylation profiles reveal novel candidate genes associated with meat quality at different age stages in hens. | |||
|date=05.04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28378745 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381223 | |||
}} | |||
* {{medline-title | |||
|title=Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice. | |||
|date=15.01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26592663 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.11.064 | |||
}} | |||
* {{medline-title | |||
|title=Dynamic changes of Apo A1 mediated by LXR/RXR/[[ABCA1]] pathway in brains of the aging rats with cerebral hypoperfusion. | |||
|date=01.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24291698 | |||
|full-text-url=https://sci-hub.do/10.1016/j.brainresbull.2013.11.004 | |||
}} | |||
* {{medline-title | |||
|title=Elevated COX2 expression and PGE2 production by downregulation of RXRα in senescent macrophages. | |||
|date=11.10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24051096 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2013.09.047 | |||
}} | |||
* {{medline-title | |||
|title=Genetic determinants of macular pigments in women of the Carotenoids in Age-Related Eye Disease Study. | |||
|date=28.03.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23404124 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626525 | |||
}} | |||
==ACTN3== | |||
* {{medline-title | |||
|title=Altered miRNA and mRNA Expression in Sika Deer Skeletal Muscle with Age. | |||
|date=06.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041309 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073773 | |||
}} | |||
* {{medline-title | |||
|title=The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature. | |||
|date=01.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30676214 | |||
|full-text-url=https://sci-hub.do/10.1123/japa.2018-0155 | |||
}} | |||
* {{medline-title | |||
|title=Is evolutionary loss our gain? The role of [[ACTN3]] p.Arg577Ter (R577X) genotype in athletic performance, ageing, and disease. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30281865 | |||
|full-text-url=https://sci-hub.do/10.1002/humu.23663 | |||
}} | |||
* {{medline-title | |||
|title=[[ACTN3]] genotype and physical function and frailty in an elderly Chinese population: the Rugao Longevity and Ageing Study. | |||
|date=01.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29447359 | |||
|full-text-url=https://sci-hub.do/10.1093/ageing/afy007 | |||
}} | |||
* {{medline-title | |||
|title=Muscle-Related Polymorphisms ([[MSTN]] rs1805086 and [[ACTN3]] rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27861536 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115755 | |||
}} | |||
* {{medline-title | |||
|title=Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27294501 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983298 | |||
}} | |||
* {{medline-title | |||
|title=The [[ACTN3]] R577X genotype is associated with muscle function in a Japanese population. | |||
|date=04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761735 | |||
|full-text-url=https://sci-hub.do/10.1139/apnm-2014-0346 | |||
}} | |||
* {{medline-title | |||
|title=1000 Norms Project: protocol of a cross-sectional study cataloging human variation. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25733400 | |||
|full-text-url=https://sci-hub.do/10.1016/j.physio.2014.12.002 | |||
}} | |||
==ASXL1== | |||
* {{medline-title | |||
|title=Aging and leukemic evolution of hematopoietic stem cells under various stress conditions. | |||
|date=05.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33292805 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643313 | |||
}} | |||
* {{medline-title | |||
|title=60 Years of clonal hematopoiesis research: From X-chromosome inactivation studies to the identification of driver mutations. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32001340 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exphem.2020.01.008 | |||
}} | |||
* {{medline-title | |||
|title=[[ASXL1]] mutation in clonal hematopoiesis. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31945396 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exphem.2020.01.002 | |||
}} | |||
* {{medline-title | |||
|title=Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31406340 | |||
|full-text-url=https://sci-hub.do/10.1038/s41569-019-0247-5 | |||
}} | |||
* {{medline-title | |||
|title=[Role of [[ASXL1]] mutations in hematological disorders]. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31281161 | |||
|full-text-url=https://sci-hub.do/10.11406/rinketsu.60.680 | |||
}} | |||
* {{medline-title | |||
|title=Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30417440 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.27752 | |||
}} | |||
* {{medline-title | |||
|title=A primer for epigenetics of hematological malignancies. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27725578 | |||
|full-text-url=https://sci-hub.do/10.11406/rinketsu.57.1835 | |||
}} | |||
* {{medline-title | |||
|title=The [[BAP1]]/[[ASXL2]] Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. | |||
|date=27.11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416890 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661380 | |||
}} | |||
==B2M== | |||
* {{medline-title | |||
|title=Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy. | |||
|date=22.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32959881 | |||
|full-text-url=https://sci-hub.do/10.1093/infdis/jiaa599 | |||
}} | |||
* {{medline-title | |||
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468 | |||
}} | |||
* {{medline-title | |||
|title=Association between serum β2-microglobulin levels and frailty in an elderly Chinese population: results from RuLAS. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081654 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652941 | |||
}} | |||
* {{medline-title | |||
|title=Non-GFR Determinants of Low-Molecular-Weight Serum Protein Filtration Markers in the Elderly: AGES-Kidney and MESA-Kidney. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28549536 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572311 | |||
}} | |||
* {{medline-title | |||
|title=Association Between Serum β -Microglobulin Levels and Prevalent and Incident Physical Frailty in Community-Dwelling Older Women. | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28140452 | |||
|full-text-url=https://sci-hub.do/10.1111/jgs.14733 | |||
}} | |||
* {{medline-title | |||
|title=A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood. | |||
|date=22.11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27874859 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121415 | |||
}} | |||
* {{medline-title | |||
|title=β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis. | |||
|date=08.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26147761 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529371 | |||
}} | |||
* {{medline-title | |||
|title=Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal. | |||
|date=20.05.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26003168 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494916 | |||
}} | |||
==BIN1== | |||
* {{medline-title | |||
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice. | |||
|date=20.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500 | |||
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866 | |||
}} | |||
* {{medline-title | |||
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. | |||
|date=28.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389 | |||
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049 | |||
}} | |||
* {{medline-title | |||
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. | |||
|date=11.04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828 | |||
}} | |||
* {{medline-title | |||
|title=Dopamine Receptor Genes Modulate Associative Memory in Old Age. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27647283 | |||
|full-text-url=https://sci-hub.do/10.1162/jocn_a_01048 | |||
}} | |||
* {{medline-title | |||
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889 | |||
}} | |||
* {{medline-title | |||
|title=Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. | |||
|date=04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25670335 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391343 | |||
}} | |||
* {{medline-title | |||
|title=The benefits of staying active in old age: physical activity counteracts the negative influence of [[PICALM]], [[BIN1]], and [[CLU]] risk alleles on episodic memory functioning. | |||
|date=06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24660791 | |||
|full-text-url=https://sci-hub.do/10.1037/a0035465 | |||
}} | |||
* {{medline-title | |||
|title=[[BIN1]] is decreased in sporadic but not familial Alzheimer's disease or in aging. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24205320 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804620 | |||
}} | |||
==BMP4== | |||
* {{medline-title | |||
|title=Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. | |||
|date=08.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32896271 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478891 | |||
}} | |||
* {{medline-title | |||
|title=Interplay between Follistatin, Activin A, and [[BMP4]] Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging. | |||
|date=25.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242421 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.05.045 | |||
}} | |||
* {{medline-title | |||
|title=Centenarians Overexpress Pluripotency-Related Genes. | |||
|date=16.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168 | |||
}} | |||
* {{medline-title | |||
|title=BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence. | |||
|date=15.11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27794120 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135304 | |||
}} | |||
* {{medline-title | |||
|title=Increased bone morphogenetic protein signaling contributes to age-related declines in neurogenesis and cognition. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26827654 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735642 | |||
}} | |||
* {{medline-title | |||
|title=Control of the Normal and Pathological Development of Neural Stem and Progenitor Cells by the PC3/Tis21/Btg2 and Btg1 Genes. | |||
|date=12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25967096 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.25038 | |||
}} | |||
* {{medline-title | |||
|title=FSH-FSHR3-stem cells in ovary surface epithelium: basis for adult ovarian biology, failure, aging, and cancer. | |||
|date=01.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25269615 | |||
|full-text-url=https://sci-hub.do/10.1530/REP-14-0220 | |||
}} | |||
* {{medline-title | |||
|title=Molecular cloning and expression analysis of prostaglandin E receptor 2 gene in cashmere goat (Capra hircus) skin during hair follicle development. | |||
|date=03.04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24555795 | |||
|full-text-url=https://sci-hub.do/10.1080/10495398.2013.826236 | |||
}} | |||
==C9== | |||
* {{medline-title | |||
|title=[[C9]]orf72 in myeloid cells suppresses STING-induced inflammation. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32814898 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484469 | |||
}} | |||
* {{medline-title | |||
|title=Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain. | |||
|date=16.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31843021 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916080 | |||
}} | |||
* {{medline-title | |||
|title=Human iPSC-derived astrocytes from ALS patients with mutated [[C9]]ORF72 show increased oxidative stress and neurotoxicity. | |||
|date=12.2019 | |date=12.2019 | ||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/ | |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31787569 | ||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/ | |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921360 | ||
}} | |||
* {{medline-title | |||
|title=Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515158 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255829 | |||
}} | |||
* {{medline-title | |||
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681 | |||
|full-text-url=https://sci-hub.do/10.1002/prca.201800024 | |||
}} | |||
* {{medline-title | |||
|title=[[C9]]orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons. | |||
|date=29.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037833 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705968 | |||
}} | |||
* {{medline-title | |||
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827 | |||
}} | |||
* {{medline-title | |||
|title=Rare variants in [[CFI]], [[C3]] and [[C9]] are associated with high risk of advanced age-related macular degeneration. | |||
|date=11.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24036952 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902040 | |||
}} | |||
==CCL4== | |||
* {{medline-title | |||
|title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau. | |||
|date=03.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082275 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978 | |||
}} | |||
* {{medline-title | |||
|title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352 | |||
|full-text-url=https://sci-hub.do/10.1620/tjem.245.29 | |||
}} | |||
* {{medline-title | |||
|title=Human Body Composition and Immunity: Visceral Adipose Tissue Produces IL-15 and Muscle Strength Inversely Correlates with NK Cell Function in Elderly Humans. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29559978 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845694 | |||
}} | |||
* {{medline-title | |||
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071 | |||
}} | |||
* {{medline-title | |||
|title=Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A receptor. | |||
|date=18.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29064819 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680557 | |||
}} | |||
* {{medline-title | |||
|title=Simultaneous time course analysis of multiple markers based on DNA microarray in incised wound in skeletal muscle for wound aging. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27376479 | |||
|full-text-url=https://sci-hub.do/10.1016/j.forsciint.2016.06.027 | |||
}} | |||
* {{medline-title | |||
|title=Changes in the expression of the Toll-like receptor system in the aging rat kidneys. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810370 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014502 | |||
}} | |||
* {{medline-title | |||
|title=Age-related brain expression and regulation of the chemokine [[CCL4]]/MIP-1β in APP/PS1 double-transgenic mice. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24607962 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977177 | |||
}} | |||
==CDK5== | |||
* {{medline-title | |||
|title=Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31636448 | |||
|full-text-url=https://sci-hub.do/10.1038/s41593-019-0505-1 | |||
}} | |||
* {{medline-title | |||
|title=CK2 inhibition protects white matter from ischemic injury. | |||
|date=20.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125643 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.08.021 | |||
}} | |||
* {{medline-title | |||
|title=CK2 inhibition confers functional protection to young and aging axons against ischemia by differentially regulating the [[CDK5]] and AKT signaling pathways. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29944965 | |||
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2018.05.011 | |||
}} | |||
* {{medline-title | |||
|title=The pathological roles of [[NDRG2]] in Alzheimer's disease, a study using animal models and APPwt-overexpressed cells. | |||
|date=08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28670853 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492714 | |||
}} | |||
* {{medline-title | |||
|title=[[APOE]]4 Induces Site-Specific Tau Phosphorylation Through Calpain-[[CDK5]] Signaling Pathway in EFAD-Tg Mice. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27087442 | |||
|full-text-url=https://sci-hub.do/10.2174/1567205013666160415154550 | |||
}} | |||
* {{medline-title | |||
|title=GENETICS OF HUMAN AGE RELATED DISORDERS. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26856084 | |||
}} | |||
* {{medline-title | |||
|title=Surgical stress induces brain-derived neurotrophic factor reduction and postoperative cognitive dysfunction via glucocorticoid receptor phosphorylation in aged mice. | |||
|date=05.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25611431 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495659 | |||
}} | |||
* {{medline-title | |||
|title=Loss-of-[[SIRT1]] function during vascular ageing: hyperphosphorylation mediated by cyclin-dependent kinase 5. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23968571 | |||
|full-text-url=https://sci-hub.do/10.1016/j.tcm.2013.07.001 | |||
}} | |||
==COL1A1== | |||
* {{medline-title | |||
|title=The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. | |||
|date=29.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32727592 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392710 | |||
}} | |||
* {{medline-title | |||
|title=Remodeling process in bone of aged rats in response to resistance training. | |||
|date=01.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593709 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118008 | |||
}} | |||
* {{medline-title | |||
|title=Diet enrichment with a specific essential free amino acid mixture improves healing of undressed wounds in aged rats. | |||
|date=01.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28669821 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.06.020 | |||
}} | |||
* {{medline-title | |||
|title=Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. | |||
|date=01.06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28385812 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495944 | |||
}} | |||
* {{medline-title | |||
|title=Scleraxis Is Essential for Tendon Differentiation by Equine Embryonic Stem Cells and in Equine Fetal Tenocytes. | |||
|date=15.03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27899062 | |||
|full-text-url=https://sci-hub.do/10.1089/scd.2016.0279 | |||
}} | |||
* {{medline-title | |||
|title=The comparison of microRNA profile of the dermis between the young and elderly. | |||
|date=05.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26899446 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2016.01.005 | |||
}} | |||
* {{medline-title | |||
|title=Molecular differences between stromal cell populations from deciduous and permanent human teeth. | |||
|date=18.04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25927523 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417277 | |||
}} | |||
* {{medline-title | |||
|title=Relationship of age and body mass index to the expression of obesity and osteoarthritis-related genes in human meniscus. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23318714 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751987 | |||
}} | |||
==COMP== | |||
* {{medline-title | |||
|title=Effect of circadian rhythm, age, training and acute lameness on serum concentrations of cartilage oligomeric matrix protein ([[COMP]]) neo-epitope in horses. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30739342 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767518 | |||
}} | |||
* {{medline-title | |||
|title=Genetic overexpression of [[COMP]]-Ang1 impairs BM microenvironment and induces senescence of BM HSCs. | |||
|date=15.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604278 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.210 | |||
}} | |||
* {{medline-title | |||
|title=Longitudinal Twin Study of Subjective Health: Differences in Genetic and Environmental Components of Variance Across Age and Sex. | |||
|date=01.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29590493 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909438 | |||
}} | |||
* {{medline-title | |||
|title=Cartilage biomarkers in the osteoarthropathy of alkaptonuria reveal low turnover and accelerated ageing. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28028161 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5188995 | |||
}} | |||
* {{medline-title | |||
|title=Scleraxis Is Essential for Tendon Differentiation by Equine Embryonic Stem Cells and in Equine Fetal Tenocytes. | |||
|date=15.03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27899062 | |||
|full-text-url=https://sci-hub.do/10.1089/scd.2016.0279 | |||
}} | |||
* {{medline-title | |||
|title=Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence. | |||
|date=16.09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27498005 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2016.08.004 | |||
}} | |||
* {{medline-title | |||
|title=Fibrotic-like changes in degenerate human intervertebral discs revealed by quantitative proteomic analysis. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26463451 | |||
|full-text-url=https://sci-hub.do/10.1016/j.joca.2015.09.020 | |||
}} | |||
* {{medline-title | |||
|title=Enhanced tissue regeneration potential of juvenile articular cartilage. | |||
|date=11.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24043472 | |||
|full-text-url=https://sci-hub.do/10.1177/0363546513502945 | |||
}} | |||
==CYP1A2== | |||
* {{medline-title | |||
|title=Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396457 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681801 | |||
}} | |||
* {{medline-title | |||
|title=Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of [[CYP1A2]]-Mediated Pharmacokinetics in Young and Elderly Chinese Adults. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767128 | |||
|full-text-url=https://sci-hub.do/10.1007/s40262-019-00737-5 | |||
}} | |||
* {{medline-title | |||
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442 | |||
}} | |||
* {{medline-title | |||
|title=Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396010 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ijheh.2017.03.007 | |||
}} | |||
* {{medline-title | |||
|title=Determination of Human Hepatic [[CYP2C8]] and [[CYP1A2]] Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28228413 | |||
|full-text-url=https://sci-hub.do/10.1124/dmd.116.074583 | |||
}} | |||
* {{medline-title | |||
|title=Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27995649 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427230 | |||
}} | |||
* {{medline-title | |||
|title=[Age-dependent [[CYP1A2]] gene polymorphism -163C>A in three ethnic groups of Bashkortostan Republic residents]. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826985 | |||
}} | |||
* {{medline-title | |||
|title=Age-related changes in hepatic activity and expression of detoxification enzymes in male rats. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23971034 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736498 | |||
}} | |||
==CYP2C19== | |||
* {{medline-title | |||
|title=Physiologically Based Pharmacokinetic Approach Can Successfully Predict Pharmacokinetics of Citalopram in Different Patient Populations. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31750550 | |||
|full-text-url=https://sci-hub.do/10.1002/jcph.1541 | |||
}} | |||
* {{medline-title | |||
|title=Longitudinal exposure of English primary care patients to pharmacogenomic drugs: An analysis to inform design of pre-emptive pharmacogenomic testing. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31454087 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6955399 | |||
}} | |||
* {{medline-title | |||
|title=The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567399 | |||
|full-text-url=https://sci-hub.do/10.1016/j.euroneuro.2018.01.003 | |||
}} | |||
* {{medline-title | |||
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442 | |||
}} | |||
* {{medline-title | |||
|title=Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396010 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ijheh.2017.03.007 | |||
}} | |||
* {{medline-title | |||
|title=Determination of Human Hepatic [[CYP2C8]] and [[CYP1A2]] Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28228413 | |||
|full-text-url=https://sci-hub.do/10.1124/dmd.116.074583 | |||
}} | |||
* {{medline-title | |||
|title=Identifying clinically relevant sources of variability: The clopidogrel challenge. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27557470 | |||
|full-text-url=https://sci-hub.do/10.1002/cpt.459 | |||
}} | |||
* {{medline-title | |||
|title=Impact of age on serum concentrations of venlafaxine and escitalopram in different [[CYP2D6]] and [[CYP2C19]] genotype subgroups. | |||
|date=08.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24858822 | |||
|full-text-url=https://sci-hub.do/10.1007/s00228-014-1696-8 | |||
}} | |||
==DCN== | |||
* {{medline-title | |||
|title=Decorin inhibits the insulin-like growth factor I signaling in bone marrow mesenchymal stem cells of aged humans. | |||
|date=26.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33257596 | |||
|full-text-url=https://sci-hub.do/10.18632/aging.202166 | |||
}} | |||
* {{medline-title | |||
|title=Classification of neurons in the adult mouse cochlear nucleus: Linear discriminant analysis. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31581200 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776397 | |||
}} | |||
* {{medline-title | |||
|title=The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102684 | |||
|full-text-url=https://sci-hub.do/10.1016/j.diabres.2019.05.009 | |||
}} | |||
* {{medline-title | |||
|title=MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30987676 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769 | |||
}} | |||
* {{medline-title | |||
|title=Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?: A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30394964 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310471 | |||
}} | |||
* {{medline-title | |||
|title=Extracellular proteoglycan decorin maintains human hair follicle stem cells. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320452 | |||
|full-text-url=https://sci-hub.do/10.1111/1346-8138.14678 | |||
}} | |||
* {{medline-title | |||
|title=Synaptic Specializations Support Frequency-Independent Purkinje Cell Output from the Cerebellar Cortex. | |||
|date=20.12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28009294 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870134 | |||
}} | |||
* {{medline-title | |||
|title=The aging human cochlear nucleus: Changes in the glial fibrillary acidic protein, intracellular calcium regulatory proteins, GABA neurotransmitter and cholinergic receptor. | |||
|date=03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24412669 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2013.12.001 | |||
}} | |||
==DNMT3B== | |||
* {{medline-title | |||
|title=Collagens and DNA methyltransferases in mare endometrosis. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31512314 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13515 | |||
}} | |||
* {{medline-title | |||
|title=Alcohol Extracts From [i]Ganoderma lucidum[/i] Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971923 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444160 | |||
}} | |||
* {{medline-title | |||
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature. | |||
|date=18.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778 | |||
}} | |||
* {{medline-title | |||
|title=Effects of Parental Aging During Embryo Development and Adult Life: The Case of Nothobranchius furzeri. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304310 | |||
|full-text-url=https://sci-hub.do/10.1089/zeb.2017.1494 | |||
}} | |||
* {{medline-title | |||
|title=Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. | |||
|date=01.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635509 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576272 | |||
}} | |||
* {{medline-title | |||
|title=Forkhead box A2 regulates biliary heterogeneity and senescence during cholestatic liver injury in mice‡. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27639079 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258713 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent expression of [[DNMT1]] and [[DNMT3B]] in PBMCs from a large European population enrolled in the MARK-AGE study. | |||
|date=08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27169697 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933658 | |||
}} | |||
* {{medline-title | |||
|title=Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27147278 | |||
|full-text-url=https://sci-hub.do/10.1111/ejh.12771 | |||
}} | |||
==ESR1== | |||
* {{medline-title | |||
|title=Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement. | |||
|date=05.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416771 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788639 | |||
}} | |||
* {{medline-title | |||
|title=Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain. | |||
|date=01.04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28334178 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093352 | |||
}} | |||
* {{medline-title | |||
|title=Age- and menopause-related differences in subcutaneous adipose tissue estrogen receptor mRNA expression. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28288896 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423653 | |||
}} | |||
* {{medline-title | |||
|title=Association of PvuII and XbaI polymorphisms on estrogen receptor alpha ([[ESR1]]) gene to changes into serum lipid profile of post-menopausal women: Effects of aging, body mass index and breast cancer incidence. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199328 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310899 | |||
}} | |||
* {{medline-title | |||
|title=Differential roles of estrogen receptors, [[ESR1]] and [[ESR2]], in adult rat spermatogenesis. | |||
|date=15.06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27004961 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mce.2016.03.024 | |||
}} | |||
* {{medline-title | |||
|title=Brain volumes in late life: gender, hormone treatment, and estrogen receptor variants. | |||
|date=03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24269019 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2013.09.026 | |||
}} | |||
* {{medline-title | |||
|title=Prospective analysis of the association between estrogen receptor gene variants and the risk of cognitive decline in elderly women. | |||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23932494 | |||
|full-text-url=https://sci-hub.do/10.1016/j.euroneuro.2013.06.003 | |||
}} | |||
* {{medline-title | |||
|title=Estrogen receptor alpha single nucleotide polymorphism as predictor of diabetes type 2 risk in hypogonadal men. | |||
|date=06.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23506158 | |||
|full-text-url=https://sci-hub.do/10.3109/13685538.2013.772134 | |||
}} | |||
==ESR2== | |||
* {{medline-title | |||
|title=Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain. | |||
|date=01.04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28334178 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093352 | |||
}} | |||
* {{medline-title | |||
|title=Age- and menopause-related differences in subcutaneous adipose tissue estrogen receptor mRNA expression. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28288896 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423653 | |||
}} | |||
* {{medline-title | |||
|title=Differential roles of estrogen receptors, [[ESR1]] and [[ESR2]], in adult rat spermatogenesis. | |||
|date=15.06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27004961 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mce.2016.03.024 | |||
}} | |||
* {{medline-title | |||
|title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460 | |||
}} | |||
* {{medline-title | |||
|title=Estrogen receptor β variants modify risk for Alzheimer's disease in a multiethnic female cohort. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24326520 | |||
|full-text-url=https://sci-hub.do/10.3233/JAD-130551 | |||
}} | |||
* {{medline-title | |||
|title=Brain volumes in late life: gender, hormone treatment, and estrogen receptor variants. | |||
|date=03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24269019 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2013.09.026 | |||
}} | |||
* {{medline-title | |||
|title=Prospective analysis of the association between estrogen receptor gene variants and the risk of cognitive decline in elderly women. | |||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23932494 | |||
|full-text-url=https://sci-hub.do/10.1016/j.euroneuro.2013.06.003 | |||
}} | |||
* {{medline-title | |||
|title=Estrogen receptor alpha single nucleotide polymorphism as predictor of diabetes type 2 risk in hypogonadal men. | |||
|date=06.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23506158 | |||
|full-text-url=https://sci-hub.do/10.3109/13685538.2013.772134 | |||
}} | |||
==FAAH== | |||
* {{medline-title | |||
|title=Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32095523 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015690 | |||
}} | |||
* {{medline-title | |||
|title=Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911178 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548519 | |||
}} | |||
* {{medline-title | |||
|title=Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease. | |||
|date=11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26976670 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neuropharm.2016.03.015 | |||
}} | |||
* {{medline-title | |||
|title=Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth. | |||
|date=08.04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26900150 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825023 | |||
}} | |||
* {{medline-title | |||
|title=Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26642910 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580823 | |||
}} | |||
* {{medline-title | |||
|title=Enhanced microglial activity in [[FAAH]](-/-) animals. | |||
|date=01.10.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25534441 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2014.12.016 | |||
}} | |||
* {{medline-title | |||
|title=Normal aging in rats and pathological aging in human Alzheimer's disease decrease [[FAAH]] activity: modulation by cannabinoid agonists. | |||
|date=12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25456842 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2014.10.011 | |||
}} | |||
* {{medline-title | |||
|title=Induction of endocannabinoid levels in juvenile rat brain following developmental chlorpyrifos exposure. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23761300 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954109 | |||
}} | |||
==GBA== | |||
* {{medline-title | |||
|title=Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease. | |||
|date=08.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31703585 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842240 | |||
}} | |||
* {{medline-title | |||
|title=[i]Malassezia[/i] and Parkinson's Disease. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396143 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667642 | |||
}} | |||
* {{medline-title | |||
|title=Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29735433 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015735 | |||
}} | |||
* {{medline-title | |||
|title=[[GBA]] mutations in Parkinson disease: earlier death but similar neuropathological features. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28834018 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657539 | |||
}} | |||
* {{medline-title | |||
|title=Cognitive and motor functioning in elderly glucocerebrosidase mutation carriers. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28728889 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647652 | |||
}} | |||
* {{medline-title | |||
|title=Age and gender-specific reference intervals for lysosomal enzymes in dried blood spot samples: A study in Indian population. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396248 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clinbiochem.2017.04.004 | |||
}} | |||
* {{medline-title | |||
|title=Minos-insertion mutant of the Drosophila [[GBA]] gene homologue showed abnormal phenotypes of climbing ability, sleep and life span with accumulation of hydroxy-glucocerebroside. | |||
|date=30.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286087 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2017.03.004 | |||
}} | |||
* {{medline-title | |||
|title=Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase ([[GBA]]) and alpha-galactosidase A ([[GLA]]) enzymes. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28098348 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.25807 | |||
}} | |||
==GLA== | |||
* {{medline-title | |||
|title=TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25. | |||
|date=17.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769448 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012510 | |||
}} | |||
* {{medline-title | |||
|title=Gamma-linolenic acid ameliorated glycation-induced memory impairment in rats. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28545346 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012036 | |||
}} | |||
* {{medline-title | |||
|title=Age and gender-specific reference intervals for lysosomal enzymes in dried blood spot samples: A study in Indian population. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28396248 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clinbiochem.2017.04.004 | |||
}} | |||
* {{medline-title | |||
|title=Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase ([[GBA]]) and alpha-galactosidase A ([[GLA]]) enzymes. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28098348 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.25807 | |||
}} | |||
* {{medline-title | |||
|title=In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27081760 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906944 | |||
}} | |||
* {{medline-title | |||
|title=The stimulatory effect of the [[TLR4]]-mediated adjuvant glucopyranosyl lipid A is well preserved in old age. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25957253 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-015-9576-x | |||
}} | |||
* {{medline-title | |||
|title=Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. | |||
|date=06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24823311 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123862 | |||
}} | |||
* {{medline-title | |||
|title=Protective effect of borage seed oil and gamma linolenic acid on DNA: in vivo and in vitro studies. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23460824 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584109 | |||
}} | |||
==GPI== | |||
* {{medline-title | |||
|title=Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain. | |||
|date=10.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32646997 | |||
|full-text-url=https://sci-hub.do/10.1126/science.aaw2622 | |||
}} | |||
* {{medline-title | |||
|title=Potential role of exercise-induced glucose-6-phosphate isomerase in skeletal muscle function. | |||
|date=30.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31337203 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651688 | |||
}} | |||
* {{medline-title | |||
|title=Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156458 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529780 | |||
}} | |||
* {{medline-title | |||
|title=Can the health of a nation be correlated to its state of internal peace? | |||
|date=01-03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27416918 | |||
|full-text-url=https://sci-hub.do/10.1080/13623699.2016.1207868 | |||
}} | |||
* {{medline-title | |||
|title=Developmental role of the cell adhesion molecule Contactin-6 in the cerebral cortex and hippocampus. | |||
|date=03.07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26939565 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986711 | |||
}} | |||
* {{medline-title | |||
|title=Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus). | |||
|date=11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26568298 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694066 | |||
}} | |||
* {{medline-title | |||
|title=Urokinase receptor and resistance to targeted anticancer agents. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26283964 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515545 | |||
}} | |||
* {{medline-title | |||
|title=The glycolytic enzyme, [[GPI]], is a functionally conserved modifier of dopaminergic neurodegeneration in Parkinson's models. | |||
|date=01.07.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24882066 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097176 | |||
}} | |||
==GSS== | |||
* {{medline-title | |||
|title=Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V [[GSS]]. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32516343 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282622 | |||
}} | |||
* {{medline-title | |||
|title=Geriatric brain tumor management part I: Meningioma. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208835 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jocn.2019.05.063 | |||
}} | |||
* {{medline-title | |||
|title=Link between cardiac function and the antioxidative defense mechanism in aged rats. | |||
|date=11.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31010674 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.03.182 | |||
}} | |||
* {{medline-title | |||
|title=Towards improving sterile insect technique: Exposure to orange oil compounds increases sexual signalling and longevity in Ceratitis capitata males of the Vienna 8 [[GSS]]. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29190755 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708806 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27004051 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800781 | |||
}} | |||
* {{medline-title | |||
|title=Comparison of Anastrepha ludens (Diptera: Tephritidae) Bisexual and Genetic Sexing (Tapachula-7) Strains: Effect of Hypoxia, Fly Density, Chilling Period, and Food Type on Fly Quality. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26685109 | |||
|full-text-url=https://sci-hub.do/10.1093/jee/tov350 | |||
}} | |||
* {{medline-title | |||
|title=The Geriatric Scoring System ([[GSS]]) for Risk Stratification in Meningioma Patients as a Predictor of Outcome in Patients Treated with Radiosurgery. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26548822 | |||
|full-text-url=https://sci-hub.do/10.1016/j.wneu.2015.10.081 | |||
}} | |||
* {{medline-title | |||
|title='Start to finish trans-institutional transdisciplinary care': a novel approach improves colorectal surgical results in frail elderly patients. | |||
|date=01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26500155 | |||
|full-text-url=https://sci-hub.do/10.1111/codi.13166 | |||
}} | |||
==GSTM1== | |||
* {{medline-title | |||
|title=The effects of everyday-life exposure to polycyclic aromatic hydrocarbons on biological age indicators. | |||
|date=03.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33272294 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713168 | |||
}} | |||
* {{medline-title | |||
|title=Carrying the T Allele of the SNP rs574344, an eQTL of [[GSTM1]], Contributes to Longevity in the Han Chinese Population. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30589570 | |||
|full-text-url=https://sci-hub.do/10.1089/gtmb.2018.0178 | |||
}} | |||
* {{medline-title | |||
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | |||
}} | |||
* {{medline-title | |||
|title=Aging-dependent DNA hypermethylation and gene expression of [[GSTM1]] involved in T cell differentiation. | |||
|date=25.07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28596482 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564710 | |||
}} | |||
* {{medline-title | |||
|title=[Age features of cytogenetic effects of spring-summer encephalitis among residents of northern western Siberia in connection with polymorphism for genes of glutathione-S-transferase]. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28556645 | |||
}} | |||
* {{medline-title | |||
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632 | |||
}} | |||
* {{medline-title | |||
|title=Effects of [[APOE]] rs429358, rs7412 and [[GSTM1]]/[[GSTT1]] Polymorphism on Plasma and Erythrocyte Antioxidant Parameters and Cognition in Old Chinese Adults. | |||
|date=24.09.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26404360 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632411 | |||
}} | |||
* {{medline-title | |||
|title=[Frequency of gene polymorphic variants (phase II) of biotransformation of [[GSTT1]] and [[GSTM1]] xenobiotics among long-livers (Precarpathian region)]. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640692 | |||
}} | |||
==HFE== | |||
* {{medline-title | |||
|title=Polyphenol Characterization and Skin-Preserving Properties of Hydroalcoholic Flower Extract from [i]Himantoglossum robertianum[/i] (Orchidaceae). | |||
|date=14.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31739534 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918203 | |||
}} | |||
* {{medline-title | |||
|title=Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-[[F10]] cells by inducing senescence. | |||
|date=15.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097108 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.06.008 | |||
}} | |||
* {{medline-title | |||
|title=Iron-processing genotypes, nutrient intakes, and cadmium levels in the Normative Aging Study: Evidence of sensitive subpopulations in cadmium risk assessment. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30059941 | |||
|full-text-url=https://sci-hub.do/10.1016/j.envint.2018.06.040 | |||
}} | |||
* {{medline-title | |||
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632 | |||
}} | |||
* {{medline-title | |||
|title=Haplotype analysis of the [[HFE]] gene among populations of Northern Eurasia, in patients with metabolic disorders or stomach cancer, and in long-lived people. | |||
|date=17.06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27317329 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912798 | |||
}} | |||
* {{medline-title | |||
|title=No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes. | |||
|date=06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946122 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709 | |||
}} | |||
* {{medline-title | |||
|title=Cumulative lead exposure is associated with reduced olfactory recognition performance in elderly men: The Normative Aging Study. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26121922 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523435 | |||
}} | |||
* {{medline-title | |||
|title=[[[CCR5]], [[CCR2]], apoe, p53, [[ITGB3]] and [[HFE]] gene polymorphism in Western Siberia long-livers]. | |||
|date=2012 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23289212 | |||
}} | |||
==HMOX1== | |||
* {{medline-title | |||
|title=Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism. | |||
|date=06.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33212416 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680814 | |||
}} | |||
* {{medline-title | |||
|title=Well-aging: A new strategy for skin homeostasis under multi-stressed conditions. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31232507 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003805 | |||
}} | |||
* {{medline-title | |||
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016 | |||
}} | |||
* {{medline-title | |||
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632 | |||
}} | |||
* {{medline-title | |||
|title=Exercise-induced Nrf2-signaling is impaired in aging. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27109910 | |||
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2016.04.024 | |||
}} | |||
* {{medline-title | |||
|title=Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27094468 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.03.014 | |||
}} | |||
* {{medline-title | |||
|title=Neurotherapeutic effects of novel HO-1 inhibitors in vitro and in a transgenic mouse model of Alzheimer's disease. | |||
|date=12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25111043 | |||
|full-text-url=https://sci-hub.do/10.1111/jnc.12927 | |||
}} | |||
* {{medline-title | |||
|title=Astroglial heme oxygenase-1 and the origin of corpora amylacea in aging and degenerating neural tissues. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24440642 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020524 | |||
}} | |||
==LBR== | |||
* {{medline-title | |||
|title=Lamin B receptor: role on chromatin structure, cellular senescence and possibly aging. | |||
|date=31.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32726434 | |||
|full-text-url=https://sci-hub.do/10.1042/BCJ20200165 | |||
}} | |||
* {{medline-title | |||
|title=The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32173784 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125286 | |||
}} | |||
* {{medline-title | |||
|title=The role of lamin B receptor in the regulation of senescence-associated secretory phenotype (SASP). | |||
|date=01.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32126237 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.111927 | |||
}} | |||
* {{medline-title | |||
|title=Lamin B receptor plays a key role in cellular senescence induced by inhibition of the proteasome. | |||
|date=11.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31825172 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996348 | |||
}} | |||
* {{medline-title | |||
|title=Lamin B receptor ([[LBR]]) is involved in the induction of cellular senescence in human cells. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30615890 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.01.001 | |||
}} | |||
* {{medline-title | |||
|title=Consequences of Lamin B1 and Lamin B Receptor Downregulation in Senescence. | |||
|date=06.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415520 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850099 | |||
}} | |||
* {{medline-title | |||
|title=Overexpression of Lamin B Receptor Results in Impaired Skin Differentiation. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26053873 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459694 | |||
}} | |||
* {{medline-title | |||
|title=Embryonic expression of the common progeroid lamin A splice mutation arrests postnatal skin development. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24305605 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331787 | |||
}} | |||
==LPL== | |||
* {{medline-title | |||
|title=Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32684467 | |||
|full-text-url=https://sci-hub.do/10.3168/jds.2020-18174 | |||
}} | |||
* {{medline-title | |||
|title=Influence of common health disorders on the length of productive life and stayability in German Holstein cows. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31677834 | |||
|full-text-url=https://sci-hub.do/10.3168/jds.2019-16985 | |||
}} | |||
* {{medline-title | |||
|title=GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29694926 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bone.2018.04.014 | |||
}} | |||
* {{medline-title | |||
|title=Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle. | |||
|date=29.06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671246 | |||
|full-text-url=https://sci-hub.do/10.4238/gmr16029091 | |||
}} | |||
* {{medline-title | |||
|title=Association of Metabolic Syndrome with Serum Adipokines in Community-Living Elderly Japanese Women: Independent Association with Plasminogen Activator-Inhibitor-1. | |||
|date=11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26451494 | |||
|full-text-url=https://sci-hub.do/10.1089/met.2015.0014 | |||
}} | |||
* {{medline-title | |||
|title=Moderate Exercise Mitigates the Detrimental Effects of Aging on Tendon Stem Cells. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26086850 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472753 | |||
}} | |||
* {{medline-title | |||
|title=Association of adiponectin with serum preheparin lipoprotein lipase mass in women independent of fat mass and distribution, insulin resistance, and inflammation. | |||
|date=10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24905278 | |||
|full-text-url=https://sci-hub.do/10.1089/met.2014.0023 | |||
}} | |||
* {{medline-title | |||
|title=[Clinical and genetic characteristics of long-livers in Moscow region]. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24640693 | |||
}} | |||
==LTA== | |||
* {{medline-title | |||
|title=Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814084 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031475 | |||
}} | |||
* {{medline-title | |||
|title=The change of pain classes over time: a latent transition analysis. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31680381 | |||
|full-text-url=https://sci-hub.do/10.1002/ejp.1502 | |||
}} | |||
* {{medline-title | |||
|title=Leisure time activities as mediating variables in functional disability progression: An application of parallel latent growth curve modeling. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30281590 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169861 | |||
}} | |||
* {{medline-title | |||
|title=The Neighborhood Built Environment and Cognitive Function of Older Persons: Results from the Singapore Longitudinal Ageing Study. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28910813 | |||
|full-text-url=https://sci-hub.do/10.1159/000480080 | |||
}} | |||
* {{medline-title | |||
|title=Changes in depression among older adults in China: A latent transition analysis. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866046 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jad.2016.11.004 | |||
}} | |||
* {{medline-title | |||
|title=Joint effect of gene-physical activity and the interactions among [[CRP]], [[TNF]]-α, and [[LTA]] polymorphisms on serum [[CRP]], [[TNF]]-α levels, and handgrip strength in community-dwelling elders in Taiwan - TCHS-E. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27056089 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005924 | |||
}} | |||
* {{medline-title | |||
|title=In vitro anti-platelet potency of ticagrelor in blood samples from infants and children. | |||
|date=09.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26210892 | |||
|full-text-url=https://sci-hub.do/10.1016/j.thromres.2015.07.013 | |||
}} | |||
* {{medline-title | |||
|title=Physical Activity, Mediterranean Diet and Biomarkers-Assessed Risk of Alzheimer's: A Multi-Modality Brain Imaging Study. | |||
|date=10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25599008 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294269 | |||
}} | |||
==MAG== | |||
* {{medline-title | |||
|title=Exploration of life satisfaction of Korean people with sensory impairments across the lifespan. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32327387 | |||
|full-text-url=https://sci-hub.do/10.1016/j.dhjo.2020.100931 | |||
}} | |||
* {{medline-title | |||
|title=Omega-3 Monoacylglyceride Effects on Longevity, Mitochondrial Metabolism and Oxidative Stress: Insights from [i]Drosophila melanogaster[/i]. | |||
|date=16.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30453574 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266923 | |||
}} | |||
* {{medline-title | |||
|title=Glial Sulfatides and Neuronal Complex Gangliosides Are Functionally Interdependent in Maintaining Myelinating Axon Integrity. | |||
|date=02.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30446529 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325269 | |||
}} | |||
* {{medline-title | |||
|title=Gray Matter Volume and Cognitive Performance During Normal Aging. A Voxel-Based Morphometry Study. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30123123 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085481 | |||
}} | |||
* {{medline-title | |||
|title=Oxidative Stress Function in Women over 40 Years of Age, Considering Their Lifestyle. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28360887 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352663 | |||
}} | |||
* {{medline-title | |||
|title=Age-related changes in retinoic, docosahexaenoic and arachidonic acid modulation in nuclear lipid metabolism. | |||
|date=15.08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27355428 | |||
|full-text-url=https://sci-hub.do/10.1016/j.abb.2016.06.017 | |||
}} | |||
* {{medline-title | |||
|title=Transcriptional and biochemical responses of monoacylglycerol acyltransferase-mediated oil synthesis and associated senescence-like responses in Nicotiana benthamiana. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24904604 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033622 | |||
}} | |||
* {{medline-title | |||
|title=Electromechanical delay of the knee extensor muscles: comparison among young, middle-age and older individuals. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24797398 | |||
|full-text-url=https://sci-hub.do/10.1111/cpf.12157 | |||
}} | |||
==MITF== | |||
* {{medline-title | |||
|title=Thymocid , a Standardized Black Cumin ([i]Nigella sativa[/i]) Seed Extract, Modulates Collagen Cross-Linking, Collagenase and Elastase Activities, and Melanogenesis in Murine B16F10 Melanoma Cells. | |||
|date=19.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32707654 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400895 | |||
}} | |||
* {{medline-title | |||
|title=HuRdling Senescence: HuR Breaks [[BRAF]]-Induced Senescence in Melanocytes and Supports Melanoma Growth. | |||
|date=21.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32455577 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281285 | |||
}} | |||
* {{medline-title | |||
|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445 | |||
|full-text-url=https://sci-hub.do/10.1111/pcmr.12811 | |||
}} | |||
* {{medline-title | |||
|title=H O promotes the aging process of melanogenesis through modulation of [[MITF]] and Nrf2. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805890 | |||
|full-text-url=https://sci-hub.do/10.1007/s11033-019-04708-8 | |||
}} | |||
* {{medline-title | |||
|title=Deregulated [[MITF]] sumoylation: A route to melanoma. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28868345 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540212 | |||
}} | |||
* {{medline-title | |||
|title=Phosphorylation of [[MITF]] by AKT affects its downstream targets and causes [[TP53]]-dependent cell senescence. | |||
|date=11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27702651 | |||
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2016.09.029 | |||
}} | |||
* {{medline-title | |||
|title=Parthenolide induces [[MITF]]-M downregulation and senescence in patient-derived [[MITF]]-M(high) melanoma cell populations. | |||
|date=23.02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26824319 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891023 | |||
}} | |||
* {{medline-title | |||
|title=Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma. | |||
|date=06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25030625 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198745 | |||
}} | |||
==NNT== | |||
* {{medline-title | |||
|title=Yoga, Health-Related Quality of Life and Mental Well-Being: A Re-analysis of a Meta-analysis Using the Quality Effects Model. | |||
|date=16.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814012 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/glz284 | |||
}} | |||
* {{medline-title | |||
|title=Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31647578 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028025 | |||
}} | |||
* {{medline-title | |||
|title=Years of Life Lost for Older Patients After Colorectal Cancer Diagnosis. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30863872 | |||
|full-text-url=https://sci-hub.do/10.1007/s00268-019-04978-0 | |||
}} | |||
* {{medline-title | |||
|title=Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30281804 | |||
|full-text-url=https://sci-hub.do/10.1111/jnc.14602 | |||
}} | |||
* {{medline-title | |||
|title=Upregulation of mitochondrial NAD levels impairs the clonogenicity of SSEA1 glioblastoma tumor-initiating cells. | |||
|date=09.06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28604662 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519015 | |||
}} | |||
* {{medline-title | |||
|title=The Health Gain Obtainable from Pancreatic Resection for Adenocarcinoma in the Elderly. | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27826771 | |||
|full-text-url=https://sci-hub.do/10.1007/s00268-016-3793-6 | |||
}} | |||
* {{medline-title | |||
|title=Restoration of Mitochondrial NAD Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27428041 | |||
|full-text-url=https://sci-hub.do/10.1002/stem.2460 | |||
}} | |||
* {{medline-title | |||
|title=Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons. | |||
|date=08.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24655393 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116450 | |||
}} | |||
==NOS2== | |||
* {{medline-title | |||
|title=Metformin alters peripheral blood mononuclear cells (PBMC) senescence biomarkers gene expression in type 2 diabetic patients. | |||
|date=01.2021 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33187870 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jdiacomp.2020.107758 | |||
}} | |||
* {{medline-title | |||
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3 | |||
}} | |||
* {{medline-title | |||
|title=Secreted α-Klotho maintains cartilage tissue homeostasis by repressing [i][[NOS2]][/i] and [i]ZIP8-MMP13[/i] catabolic axis. | |||
|date=19.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29920476 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046234 | |||
}} | |||
* {{medline-title | |||
|title=Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging. | |||
|date=28.12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031022 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198498 | |||
}} | |||
* {{medline-title | |||
|title=All-trans retinoic acid (ATRA) prevents lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment in aged rats. | |||
|date=15.11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27806872 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jneuroim.2016.10.004 | |||
}} | |||
* {{medline-title | |||
|title=TNFα antagonization alters [[NOS2]] dependent nasopharyngeal carcinoma tumor growth. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25912222 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2015.04.003 | |||
}} | |||
* {{medline-title | |||
|title=Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli. | |||
|date=09.04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25890218 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397943 | |||
}} | |||
* {{medline-title | |||
|title=Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans. | |||
|date=04.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23572278 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-013-9421-z | |||
}} | |||
==NPS== | |||
* {{medline-title | |||
|title=Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging. | |||
|date=28.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923322 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438979 | |||
}} | |||
* {{medline-title | |||
|title=Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30902566 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jagp.2019.01.215 | |||
}} | |||
* {{medline-title | |||
|title=The course of neuropsychiatric symptoms in patients with dementia in primary care. | |||
|date=31.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30517631 | |||
|full-text-url=https://sci-hub.do/10.1093/fampra/cmy117 | |||
}} | |||
* {{medline-title | |||
|title=Serum calcium levels and neuropsychological performance in depression and matched healthy controls: Reversal of correlation a marker of the aging cognitive clock? | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29587243 | |||
|full-text-url=https://sci-hub.do/10.1016/j.psyneuen.2018.03.012 | |||
}} | |||
* {{medline-title | |||
|title=Persistent use of psychotropic drugs in nursing home residents in Norway. | |||
|date=13.02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28193181 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307887 | |||
}} | |||
* {{medline-title | |||
|title=FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. | |||
|date=14.07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27447426 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981903 | |||
}} | |||
* {{medline-title | |||
|title=Cardiorenal fibrosis and dysfunction in aging: Imbalance in mediators and regulators of collagen. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26774586 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754975 | |||
}} | |||
* {{medline-title | |||
|title=Personalized technology to support older adults with and without cognitive impairment living at home. | |||
|date=02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25614507 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819239 | |||
}} | |||
==PDE4C== | |||
* {{medline-title | |||
|title=Age prediction in living: Forensic epigenetic age estimation based on blood samples. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721866 | |||
|full-text-url=https://sci-hub.do/10.1016/j.legalmed.2020.101763 | |||
}} | |||
* {{medline-title | |||
|title=Age Estimation Based on DNA Methylation Using Blood Samples From Deceased Individuals. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31490551 | |||
|full-text-url=https://sci-hub.do/10.1111/1556-4029.14185 | |||
}} | |||
* {{medline-title | |||
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637 | |||
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006 | |||
}} | |||
* {{medline-title | |||
|title=Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27337627 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2016.06.005 | |||
}} | |||
* {{medline-title | |||
|title=Plasma Amyloid Beta 1-42 and DNA Methylation Pattern Predict Accelerated Aging in Young Subjects with Down Syndrome. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27234618 | |||
|full-text-url=https://sci-hub.do/10.1007/s12017-016-8413-y | |||
}} | |||
* {{medline-title | |||
|title=Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26861500 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798846 | |||
}} | |||
* {{medline-title | |||
|title=Improved age determination of blood and teeth samples using a selected set of DNA methylation markers. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26280308 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844214 | |||
}} | |||
* {{medline-title | |||
|title=Aging of blood can be tracked by DNA methylation changes at just three CpG sites. | |||
|date=03.02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24490752 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053864 | |||
}} | |||
==PDK1== | |||
* {{medline-title | |||
|title=Inhibition of 3-phosphoinositide-dependent protein kinase 1 ([[PDK1]]) can revert cellular senescence in human dermal fibroblasts. | |||
|date=08.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33229519 | |||
|full-text-url=https://sci-hub.do/10.1073/pnas.1920338117 | |||
}} | |||
* {{medline-title | |||
|title=The Impact of the PI3K/Akt Signaling Pathway in Anxiety and Working Memory in Young and Middle-Aged [[PDK1]] K465E Knock-In Mice. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32457586 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225327 | |||
}} | |||
* {{medline-title | |||
|title=Peripheral Circulating Exosomal miRNAs Potentially Contribute to the Regulation of Molecular Signaling Networks in Aging. | |||
|date=11.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32168775 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139634 | |||
}} | |||
* {{medline-title | |||
|title=Vps15 is critical to mediate autophagy in AngII treated HUVECs probably by [[PDK1]]/PKC signaling pathway. | |||
|date=15.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31356904 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116701 | |||
}} | |||
* {{medline-title | |||
|title=Acupuncture Administration Improves Cognitive Functions and Alleviates Inflammation and Nuclear Damage by Regulating Phosphatidylinositol 3 Kinase (PI3K)/Phosphoinositol-Dependent Kinase 1 ([[PDK1]])/Novel Protein Kinase C (nPKC)/Rac 1 Signaling Pathway in Senescence-Accelerated Prone 8 (SAM-P8) Mice. | |||
|date=01.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31152645 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559003 | |||
}} | |||
* {{medline-title | |||
|title=Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28632756 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478092 | |||
}} | |||
* {{medline-title | |||
|title=Selective deletion of Pten in theca-interstitial cells leads to androgen excess and ovarian dysfunction in mice. | |||
|date=15.03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28137614 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mce.2017.01.043 | |||
}} | |||
* {{medline-title | |||
|title=Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24516402 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916422 | |||
}} | |||
==PPID== | |||
* {{medline-title | |||
|title=Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32058159 | |||
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2020.110013 | |||
}} | |||
* {{medline-title | |||
|title=Epidemiology of pituitary pars intermedia dysfunction: A systematic literature review of clinical presentation, disease prevalence and risk factors. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29704935 | |||
|full-text-url=https://sci-hub.do/10.1016/j.tvjl.2018.03.002 | |||
}} | |||
* {{medline-title | |||
|title=Effect of Age, Season, Body Condition, and Endocrine Status on Serum Free Cortisol Fraction and Insulin Concentration in Horses. | |||
|date=03-04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26860336 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913614 | |||
}} | |||
* {{medline-title | |||
|title=Age-related Qualitative Histological and Quantitative Stereological Changes in the Equine Pituitary. | |||
|date=02-04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26810844 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jcpa.2015.11.006 | |||
}} | |||
* {{medline-title | |||
|title=What's New in Old Horses? Postmortem Diagnoses in Mature and Aged Equids. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26459516 | |||
|full-text-url=https://sci-hub.do/10.1177/0300985815608674 | |||
}} | |||
* {{medline-title | |||
|title=Pituitary pars intermedia dysfunction does not necessarily impair insulin sensitivity in old horses. | |||
|date=01.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25240230 | |||
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2014.07.003 | |||
}} | |||
* {{medline-title | |||
|title=Evaluation of the effects of age and pituitary pars intermedia dysfunction on corneal sensitivity in horses. | |||
|date=07.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23802675 | |||
|full-text-url=https://sci-hub.do/10.2460/ajvr.74.7.1030 | |||
}} | |||
* {{medline-title | |||
|title=Comparison of hair follicle histology between horses with pituitary pars intermedia dysfunction and excessive hair growth and normal aged horses. | |||
|date=02.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23331700 | |||
|full-text-url=https://sci-hub.do/10.1111/j.1365-3164.2012.01080.x | |||
}} | |||
==PSEN1== | |||
* {{medline-title | |||
|title=Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease. | |||
|date=20.05.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27207465 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875608 | |||
}} | |||
* {{medline-title | |||
|title=White Matter Abnormalities Track Disease Progression in [[PSEN1]] Autosomal Dominant Alzheimer's Disease. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26923015 | |||
|full-text-url=https://sci-hub.do/10.3233/JAD-150899 | |||
}} | |||
* {{medline-title | |||
|title=Characterization of Amyloid-β Deposits in Bovine Brains. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26890772 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927890 | |||
}} | |||
* {{medline-title | |||
|title=Functions of miR-9 and miR-9* during Aging in SAMP8 Mice and Their Possible Mechanisms. | |||
|date=06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26149132 | |||
|full-text-url=https://sci-hub.do/10.3881/j.issn.1000-503X.2015.03.001 | |||
}} | |||
* {{medline-title | |||
|title=DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25933409 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416920 | |||
}} | |||
* {{medline-title | |||
|title=Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study. | |||
|date=03.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25580592 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355261 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent, non-cell-autonomous deposition of amyloid from synthesis of β-amyloid by cells other than excitatory neurons. | |||
|date=05.03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24599465 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942582 | |||
}} | |||
* {{medline-title | |||
|title=Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors. | |||
|date=20.10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24138759 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853710 | |||
}} | |||
==RAD50== | |||
* {{medline-title | |||
|title=[[ATM]] Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31781094 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856652 | |||
}} | |||
* {{medline-title | |||
|title=Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells. | |||
|date=01.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775409 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172637 | |||
}} | |||
* {{medline-title | |||
|title=Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis. | |||
|date=01.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412544 | |||
|full-text-url=https://sci-hub.do/10.1016/j.molp.2017.03.011 | |||
}} | |||
* {{medline-title | |||
|title=HIF-1α and rapamycin act as gerosuppressant in multiple myeloma cells upon genotoxic stress. | |||
|date=17.08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27340936 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993538 | |||
}} | |||
* {{medline-title | |||
|title=Immunochip analysis identifies association of the [[RAD50]]/IL13 region with human longevity. | |||
|date=06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27004735 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854908 | |||
}} | |||
* {{medline-title | |||
|title=Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. | |||
|date=29.09.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416764 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598835 | |||
}} | |||
* {{medline-title | |||
|title=Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells. | |||
|date=06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24747666 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/glu019 | |||
}} | |||
* {{medline-title | |||
|title=Copy neutral loss of heterozygosity is more frequent in older ovarian cancer patients. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23716468 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767172 | |||
}} | |||
==SCT== | |||
* {{medline-title | |||
|title=Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528961 | |||
|full-text-url=https://sci-hub.do/10.1519/JSC.0000000000002536 | |||
}} | |||
* {{medline-title | |||
|title=High-intensity interval training improves acute plasma volume responses to exercise that is age dependent. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29464883 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820462 | |||
}} | |||
* {{medline-title | |||
|title=Communication technology adoption among older adult veterans: the interplay of social and cognitive factors. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29019416 | |||
|full-text-url=https://sci-hub.do/10.1080/13607863.2017.1381946 | |||
}} | |||
* {{medline-title | |||
|title=Repeatability of Choroidal Thickness Measurements on Enhanced Depth Imaging Optical Coherence Tomography Using Different Posterior Boundaries. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27345731 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687829 | |||
}} | |||
* {{medline-title | |||
|title=HIV cure strategies: how good must they be to improve on current antiretroviral therapy? | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25397616 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232561 | |||
}} | |||
* {{medline-title | |||
|title=Quadriceps intramuscular fat fraction rather than muscle size is associated with knee osteoarthritis. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24361743 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932784 | |||
}} | |||
* {{medline-title | |||
|title=Robust measurement of telomere length in single cells. | |||
|date=21.05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23661059 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666709 | |||
}} | |||
* {{medline-title | |||
|title=The effectiveness of stem cell therapies on health-related quality of life and life expectancy in comparison with conventional supportive medical treatment in patients suffering from end-stage liver disease. | |||
|date=25.02.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23510679 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706779 | |||
}} | |||
==SNCA== | |||
* {{medline-title | |||
|title=Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease. | |||
|date=22.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31758049 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874660 | |||
}} | |||
* {{medline-title | |||
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869 | |||
}} | |||
* {{medline-title | |||
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes. | |||
|date=04.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent accumulation of oligomeric [[SNCA]]/α-synuclein from impaired degradation in mutant [[LRRK2]] knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA). | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30983487 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984454 | |||
}} | |||
* {{medline-title | |||
|title=Caloric restriction rescues yeast cells from alpha-synuclein toxicity through autophagic control of proteostasis. | |||
|date=07.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530923 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326672 | |||
}} | |||
* {{medline-title | |||
|title=Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286171 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501279 | |||
}} | |||
* {{medline-title | |||
|title=DNA methylation levels of α-synuclein intron 1 in the aging brain. | |||
|date=12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26422361 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2015.08.028 | |||
}} | |||
* {{medline-title | |||
|title=Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model. | |||
|date=15.10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24082145 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801069 | |||
}} | |||
==SOD3== | |||
* {{medline-title | |||
|title=Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. | |||
|date=31.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31940721 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999708 | |||
}} | |||
* {{medline-title | |||
|title=Prenatal hypoxia affected endothelium-dependent vasodilation in mesenteric arteries of aged offspring via increased oxidative stress. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30617312 | |||
|full-text-url=https://sci-hub.do/10.1038/s41440-018-0181-7 | |||
}} | |||
* {{medline-title | |||
|title=Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222787 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141073 | |||
}} | |||
* {{medline-title | |||
|title=In silico analysis and molecular dynamics simulation of human superoxide dismutase 3 ([[SOD3]]) genetic variants. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206983 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.27636 | |||
}} | |||
* {{medline-title | |||
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13091 | |||
}} | |||
* {{medline-title | |||
|title=Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28767699 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540417 | |||
}} | |||
* {{medline-title | |||
|title=Extracellular superoxide dismutase deficiency impairs wound healing in advanced age by reducing neovascularization and fibroblast function. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26663425 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998179 | |||
}} | |||
* {{medline-title | |||
|title=Superoxide dismutase gene polymorphisms in patients with age-related cataract. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23289810 | |||
|full-text-url=https://sci-hub.do/10.3109/13816810.2012.746377 | |||
}} | |||
==TIGIT== | |||
* {{medline-title | |||
|title=Association of Epigenetic Age and p16INK4a With Markers of T-Cell Composition in a Healthy Cohort. | |||
|date=13.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32361724 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662168 | |||
}} | |||
* {{medline-title | |||
|title=Implications of Immune Checkpoint Expression During Aging in HIV-Infected People on Antiretroviral Therapy. | |||
|date=11-12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31578868 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862963 | |||
}} | |||
* {{medline-title | |||
|title=Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30768970 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jtho.2019.01.024 | |||
}} | |||
* {{medline-title | |||
|title=Multivariate Computational Analysis of Gamma Delta T Cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV Aging. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30568654 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290897 | |||
}} | |||
* {{medline-title | |||
|title=Characterization of Blimp-1 function in effector regulatory T cells. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29724515 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jaut.2018.04.003 | |||
}} | |||
* {{medline-title | |||
|title=T-cell Immunoglobulin and ITIM Domain Contributes to CD8 T-cell Immunosenescence. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29349889 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847879 | |||
}} | |||
* {{medline-title | |||
|title=Long-Lived [[CD4]] IFN-γ T Cells rather than Short-Lived [[CD4]] IFN-γ IL-10 T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection. | |||
|date=15.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27630165 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055201 | |||
}} | |||
* {{medline-title | |||
|title=Combinatorial approach to cancer immunotherapy: strength in numbers. | |||
|date=08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27256570 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608090 | |||
}} | |||
==TIMP1== | |||
* {{medline-title | |||
|title=Senescence Reprogramming by [[TIMP1]] Deficiency Promotes Prostate Cancer Metastasis. | |||
|date=26.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33186519 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ccell.2020.10.012 | |||
}} | |||
* {{medline-title | |||
|title=Design, cyclization, and optimization of [[MMP13]]-[[TIMP1]] interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352228 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.10.141 | |||
}} | |||
* {{medline-title | |||
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478 | |||
}} | |||
* {{medline-title | |||
|title=Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1. | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866058 | |||
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2016.10.002 | |||
}} | |||
* {{medline-title | |||
|title=Effect of [[TIMP1]] transfection on [[PTEN]] expression in human kidney proximal tubular cells. | |||
|date=21.12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26782378 | |||
|full-text-url=https://sci-hub.do/10.4238/2015.December.21.6 | |||
}} | |||
* {{medline-title | |||
|title=Biological Effects Induced by Specific Advanced Glycation End Products in the Reconstructed Skin Model of Aging. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26309782 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497626 | |||
}} | |||
* {{medline-title | |||
|title=Fat and Sucrose Intake Induces Obesity-Related Bone Metabolism Disturbances: Kinetic and Reversibility Studies in Growing and Adult Rats. | |||
|date=01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26175082 | |||
|full-text-url=https://sci-hub.do/10.1002/jbmr.2596 | |||
}} | |||
* {{medline-title | |||
|title=Exercise training initiated in late middle age attenuates cardiac fibrosis and advanced glycation end-product accumulation in senescent rats. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24280067 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2013.11.006 | |||
}} | |||
==TRPM2== | |||
* {{medline-title | |||
|title=Paraquat as an Environmental Risk Factor in Parkinson's Disease Accelerates Age-Related Degeneration Via Rapid Influx of Extracellular Zn into Nigral Dopaminergic Neurons. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31119555 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-019-01642-5 | |||
}} | |||
* {{medline-title | |||
|title=Pathophysiological Role of [[TRPM2]] in Age-Related Cognitive Impairment in Mice. | |||
|date=01.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30999030 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2019.04.012 | |||
}} | |||
* {{medline-title | |||
|title=The [[TRPM2]] channel nexus from oxidative damage to Alzheimer's pathologies: An emerging novel intervention target for age-related dementia. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30009973 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.002 | |||
}} | |||
* {{medline-title | |||
|title=[[TRPM2]] in the Brain: Role in Health and Disease. | |||
|date=22.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037128 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070997 | |||
}} | |||
* {{medline-title | |||
|title=mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29842890 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.05.008 | |||
}} | |||
* {{medline-title | |||
|title=Prolactin protects retinal pigment epithelium by inhibiting sirtuin 2-dependent cell death. | |||
|date=05.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27322457 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909382 | |||
}} | |||
* {{medline-title | |||
|title=Extended therapeutic window of a novel peptide inhibitor of [[TRPM2]] channels following focal cerebral ischemia. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27317297 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240152 | |||
}} | |||
* {{medline-title | |||
|title=The Protective Role of Selenium on Scopolamine-Induced Memory Impairment, Oxidative Stress, and Apoptosis in Aged Rats: The Involvement of [[TRPM2]] and [[TRPV1]] Channels. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27021021 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-016-9835-0 | |||
}} | |||
==TRPV4== | |||
* {{medline-title | |||
|title=[[TRPV4]] receptor as a functional sensory molecule in bladder urothelium: Stretch-independent, tissue-specific actions and pathological implications. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31914645 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973053 | |||
}} | |||
* {{medline-title | |||
|title=Exercise restores impaired endothelium-derived hyperpolarizing factor-mediated vasodilation in aged rat aortic arteries via the [[TRPV4]]-K 2.3 signaling complex. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31564840 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731547 | |||
}} | |||
* {{medline-title | |||
|title=Autonomic dysregulation at multiple sites is implicated in age-associated underactive bladder in female mice. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30932250 | |||
|full-text-url=https://sci-hub.do/10.1002/nau.23990 | |||
}} | |||
* {{medline-title | |||
|title=Reduced bladder responses to capsaicin and GSK-1016790A in retired-breeder female rats with diminished volume sensitivity. | |||
|date=01.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019934 | |||
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00198.2018 | |||
}} | |||
* {{medline-title | |||
|title=Cartilage-Specific Knockout of the Mechanosensory Ion Channel [[TRPV4]] Decreases Age-Related Osteoarthritis. | |||
|date=08.07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27388701 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937413 | |||
}} | |||
* {{medline-title | |||
|title=Increasing [[TRPV4]] expression restores flow-induced dilation impaired in mesenteric arteries with aging. | |||
|date=07.03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26947561 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780030 | |||
}} | |||
* {{medline-title | |||
|title=Berberine via suppression of transient receptor potential vanilloid 4 channel improves vascular stiffness in mice. | |||
|date=11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26177349 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627566 | |||
}} | |||
* {{medline-title | |||
|title=Age-related changes in the distribution of transient receptor potential vanilloid 4 channel ([[TRPV4]]) in the central nervous system of rats. | |||
|date=10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24917364 | |||
|full-text-url=https://sci-hub.do/10.1007/s10735-014-9578-z | |||
}} | |||
==TSC2== | |||
* {{medline-title | |||
|title=AMPK/[[TSC2]]/mTOR pathway regulates replicative senescence of human vascular smooth muscle cells. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30542441 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257130 | |||
}} | |||
* {{medline-title | |||
|title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging. | |||
|date=25.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052 | |||
}} | |||
* {{medline-title | |||
|title=[[FTO]] is involved in Alzheimer's disease by targeting [[TSC1]]-mTOR-Tau signaling. | |||
|date=25.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501742 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.02.201 | |||
}} | |||
* {{medline-title | |||
|title=Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29023667 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716871 | |||
}} | |||
* {{medline-title | |||
|title=Complex inhibition of autophagy by mitochondrial aldehyde dehydrogenase shortens lifespan and exacerbates cardiac aging. | |||
|date=08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28347844 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2017.03.016 | |||
}} | |||
* {{medline-title | |||
|title=Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells. | |||
|date=01.08.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24858802 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bcp.2014.05.009 | |||
}} | |||
* {{medline-title | |||
|title=mTOR inactivation by ROS-JNK-p53 pathway plays an essential role in psedolaric acid B induced autophagy-dependent senescence in murine fibrosarcoma L929 cells. | |||
|date=05.09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23810968 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2013.05.051 | |||
}} | |||
* {{medline-title | |||
|title=Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23744272 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759338 | |||
}} | |||
==UCHL1== | |||
* {{medline-title | |||
|title=Abolishing [[UCHL1]]'s hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice. | |||
|date=04.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33159930 | |||
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2020.113524 | |||
}} | |||
* {{medline-title | |||
|title=FAM96B inhibits the senescence of dental pulp stem cells. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32039527 | |||
|full-text-url=https://sci-hub.do/10.1002/cbin.11319 | |||
}} | |||
* {{medline-title | |||
|title=Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28407635 | |||
|full-text-url=https://sci-hub.do/10.1159/000468944 | |||
}} | |||
* {{medline-title | |||
|title=Life and death in the trash heap: The ubiquitin proteasome pathway and [[UCHL1]] in brain aging, neurodegenerative disease and cerebral Ischemia. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27702698 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5250550 | |||
}} | |||
* {{medline-title | |||
|title=Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27260470 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2016.03.008 | |||
}} | |||
* {{medline-title | |||
|title=Effect of age on expression of spermatogonial markers in bovine testis and isolated cells. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27180120 | |||
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2016.04.004 | |||
}} | |||
* {{medline-title | |||
|title=It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and [[UCHL1]] in Alzheimer Disease. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26881020 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736377 | |||
}} | |||
* {{medline-title | |||
|title=Loss of [[UCHL1]] promotes age-related degenerative changes in the enteric nervous system. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24994982 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063237 | |||
}} | |||
==VDAC1== | |||
* {{medline-title | |||
|title=Low abundance of [[NDUFV2]] and [[NDUFS4]] subunits of the hydrophilic complex I domain and [[VDAC1]] predicts mammalian longevity. | |||
|date=07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32353747 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191849 | |||
}} | |||
* {{medline-title | |||
|title=17β-estradiol inhibits H O -induced senescence in HUVEC cells through upregulating [[SIRT3]] expression and promoting autophagy. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32172411 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09868-w | |||
}} | |||
* {{medline-title | |||
|title=Changes in the expression of oxidative phosphorylation complexes in the aging intestinal mucosa. | |||
|date=01.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32173460 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110924 | |||
}} | |||
* {{medline-title | |||
|title=Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice. | |||
|date=05.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31806023 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896328 | |||
}} | |||
* {{medline-title | |||
|title=Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055 | |||
}} | |||
* {{medline-title | |||
|title=The Immp2l mutation causes age-dependent degeneration of cerebellar granule neurons prevented by antioxidant treatment. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26616244 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717271 | |||
}} | |||
* {{medline-title | |||
|title=The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25910621 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854160 | |||
}} | |||
* {{medline-title | |||
|title=Curcumin prevents mitochondrial dysfunction in the brain of the senescence-accelerated mouse-prone 8. | |||
|date=04.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23422877 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2013.02.014 | |||
}} | |||
==XRCC1== | |||
* {{medline-title | |||
|title=Impairment of Pol β-related DNA Base-excision Repair Leads to Ovarian Aging in Mice. | |||
|date=20.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33223510 | |||
|full-text-url=https://sci-hub.do/10.18632/aging.104123 | |||
}} | |||
* {{medline-title | |||
|title=Base excision repair but not DNA double-strand break repair is impaired in aged human adipose-derived stem cells. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31782607 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996963 | |||
}} | |||
* {{medline-title | |||
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats]. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111059 | |||
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180408.005 | |||
}} | |||
* {{medline-title | |||
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081 | |||
}} | |||
* {{medline-title | |||
|title=[[XRCC1]] and XPD genetic polymorphisms and susceptibility to age-related cataract: a meta-analysis. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25873778 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384174 | |||
}} | |||
* {{medline-title | |||
|title=Polymorphisms of DNA repair genes XPD (Lys751Gln) and [[XRCC1]] (Arg399Gln), and the risk of age-related cataract: a meta-analysis. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25285569 | |||
|full-text-url=https://sci-hub.do/10.3109/02713683.2014.957325 | |||
}} | |||
* {{medline-title | |||
|title=Association between DNA repair genes (XPD and [[XRCC1]]) polymorphisms and susceptibility to age-related cataract ([[ARC]]): a meta-analysis. | |||
|date=08.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24906341 | |||
|full-text-url=https://sci-hub.do/10.1007/s00417-014-2679-2 | |||
}} | |||
* {{medline-title | |||
|title=Polymorphisms in [[ERCC1]] C8092A predict progression-free survival in metastatic/recurrent nasopharyngeal carcinoma treated with cisplatin-based chemotherapy. | |||
|date=08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23712330 | |||
|full-text-url=https://sci-hub.do/10.1007/s00280-013-2196-8 | |||
}} | |||
==AGA== | |||
* {{medline-title | |||
|title=Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32125089 | |||
|full-text-url=https://sci-hub.do/10.1111/jocd.13355 | |||
}} | |||
* {{medline-title | |||
|title=Relationship between androgenic alopecia and white matter hyperintensities in apparently healthy subjects. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250269 | |||
|full-text-url=https://sci-hub.do/10.1007/s11682-019-00147-y | |||
}} | |||
* {{medline-title | |||
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756 | |||
}} | |||
* {{medline-title | |||
|title=The Impact of Being Born Preterm or Small for Gestational Age on Early Vascular Aging in Adolescents. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29960764 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jpeds.2018.05.056 | |||
}} | |||
* {{medline-title | |||
|title=Adult height of preterm infants: a longitudinal cohort study. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27998884 | |||
|full-text-url=https://sci-hub.do/10.1136/archdischild-2016-310469 | |||
}} | |||
* {{medline-title | |||
|title=The telomere attrition rate is not accelerated in women born small for gestational age: A birth cohort study. | |||
|date=05.02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27871926 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2016.11.030 | |||
}} | |||
* {{medline-title | |||
|title=Does prostaglandin D2 hold the cure to male pattern baldness? | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24521203 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982925 | |||
}} | |||
==ALB== | |||
* {{medline-title | |||
|title=Effects of Age on Inflammatory Profiles and Nutrition/Energy Metabolism in Domestic Cats. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33262938 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695597 | |||
}} | |||
* {{medline-title | |||
|title=Expression of Transferrin and Albumin in the Sperm-Storage Tubules of Japanese Quail and their Possible Involvement in Long-Term Sperm Storage. | |||
|date=25.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32174770 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063080 | |||
}} | |||
* {{medline-title | |||
|title=Blood Chemistry Reference Values for Free-Ranging Asiatic Black Bears ( Ursus thibetanus) by Season, Age, and Sex. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29671714 | |||
|full-text-url=https://sci-hub.do/10.7589/2017-08-201 | |||
}} | |||
* {{medline-title | |||
|title=Higher serum albumin was related with diabetes incidence and the impact of BMI changes: Based on cohort study of 18,384 Chinese male elderly. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29033312 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jdiacomp.2017.08.015 | |||
}} | |||
* {{medline-title | |||
|title=Estimating the survival advantage based on telomere length and serum biomarkers of aging. | |||
|date=01.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28764708 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540222 | |||
}} | |||
* {{medline-title | |||
|title=HEMATOLOGY AND PLASMA CHEMISTRY OF THE PLOUGHSHARE TORTOISE (ASTROCHELYS YNIPHORA) IN A CAPTIVE BREEDING PROGRAM. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28363080 | |||
|full-text-url=https://sci-hub.do/10.1638/2016-0201.1 | |||
}} | |||
* {{medline-title | |||
|title=Too old to have children? Lessons from natural fertility populations. | |||
|date=06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24676403 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389129 | |||
}} | |||
==AMPH== | |||
* {{medline-title | |||
|title=Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood. | |||
|date=01.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29792867 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026035 | |||
}} | |||
* {{medline-title | |||
|title=The effects of amphetamine exposure on juvenile rats on the neuronal morphology of the limbic system at prepubertal, pubertal and postpubertal ages. | |||
|date=11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27208629 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2016.05.004 | |||
}} | |||
* {{medline-title | |||
|title=Amphetamine modulates brain signal variability and working memory in younger and older adults. | |||
|date=16.06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26034283 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475975 | |||
}} | |||
* {{medline-title | |||
|title=Adolescent exposure to cocaine, amphetamine, and methylphenidate cross-sensitizes adults to methamphetamine with drug- and sex-specific effects. | |||
|date=15.03.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25496784 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2014.12.002 | |||
}} | |||
* {{medline-title | |||
|title=Age of exposure-dependent effects of amphetamine on behavioral flexibility. | |||
|date=01.09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23756139 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742571 | |||
}} | |||
* {{medline-title | |||
|title=Concurrent choice for social interaction and amphetamine using conditioned place preference in rats: effects of age and housing condition. | |||
|date=01.05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23540449 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628407 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent effects of repeated amphetamine exposure on working memory in rats. | |||
|date=01.04.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23291159 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566264 | |||
}} | |||
==ATF3== | |||
* {{medline-title | |||
|title=[[ATF3]] represses [[PINK1]] gene transcription in lung epithelial cells to control mitochondrial homeostasis. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29363258 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866 | |||
}} | |||
* {{medline-title | |||
|title=p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells. | |||
|date=15.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28765281 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602387 | |||
}} | |||
* {{medline-title | |||
|title=Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival. | |||
|date=04.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28475871 | |||
|full-text-url=https://sci-hub.do/10.1016/j.molcel.2017.04.005 | |||
}} | |||
* {{medline-title | |||
|title=Rutin protects against aging-related metabolic dysfunction. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26804783 | |||
|full-text-url=https://sci-hub.do/10.1039/c5fo01036e | |||
}} | |||
* {{medline-title | |||
|title=Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26241743 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524632 | |||
}} | |||
* {{medline-title | |||
|title=Activation of autophagic pathways is related to growth inhibition and senescence in cutaneous squamous cell carcinoma. | |||
|date=10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25046976 | |||
|full-text-url=https://sci-hub.do/10.1111/exd.12515 | |||
}} | |||
* {{medline-title | |||
|title=Age-related brain expression and regulation of the chemokine [[CCL4]]/MIP-1β in APP/PS1 double-transgenic mice. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24607962 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977177 | |||
}} | |||
==ATG12== | |||
* {{medline-title | |||
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296 | |||
}} | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
* {{medline-title | |||
|title=Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28286171 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501279 | |||
}} | |||
* {{medline-title | |||
|title=Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging. | |||
|date=26.02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28238968 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361683 | |||
}} | |||
* {{medline-title | |||
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853 | |||
}} | |||
* {{medline-title | |||
|title=Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27825071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099282 | |||
}} | |||
* {{medline-title | |||
|title=Follicle-stimulating hormone promotes age-related endometrial atrophy through cross-talk with transforming growth factor beta signal transduction pathway. | |||
|date=04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25393561 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364840 | |||
}} | |||
==ATRX== | |||
* {{medline-title | |||
|title=[[ATRX]]-[[DAXX]] Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31361513 | |||
|full-text-url=https://sci-hub.do/10.1089/dna.2019.4752 | |||
}} | |||
* {{medline-title | |||
|title=Inactivation of hepatic [[ATRX]] in [i]Atrx[/i] Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine. | |||
|date=07.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883366 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046231 | |||
}} | |||
* {{medline-title | |||
|title=Mechanistic understanding of the role of [[ATRX]] in senescence provides new insight for combinatorial therapies with [[CDK4]] inhibitors. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29404388 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791849 | |||
}} | |||
* {{medline-title | |||
|title=GBM-associated mutations and altered protein expression are more common in young patients. | |||
|date=25.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491 | |||
}} | |||
* {{medline-title | |||
|title=Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes. | |||
|date=01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26577303 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853592 | |||
}} | |||
* {{medline-title | |||
|title=[[MDM2]] turnover and expression of [[ATRX]] determine the choice between quiescence and senescence in response to [[CDK4]] inhibition. | |||
|date=10.04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25803170 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480747 | |||
}} | |||
* {{medline-title | |||
|title=Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. | |||
|date=05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23563309 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635723 | |||
}} | |||
==CBL== | |||
* {{medline-title | |||
|title=Effects of cerebrolysin on nerve growth factor system in the aging rat brain. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172008 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701766 | |||
}} | |||
* {{medline-title | |||
|title=Skeletal Muscle CAP Expression Increases after Dietary Restriction and Aerobic Training in Women with a History of Gestational Diabetes. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28989819 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628746 | |||
}} | |||
* {{medline-title | |||
|title=Intranasal Cerebrolysin Attenuates Learning and Memory Impairments in D-galactose-Induced Senescence in Mice. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27894939 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.11.011 | |||
}} | |||
* {{medline-title | |||
|title=Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick's disease and fronto-temporal tauopathies. | |||
|date=26.11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26611895 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662012 | |||
}} | |||
* {{medline-title | |||
|title=Cerebrolysin Accelerates Metamorphosis and Attenuates Aging-Accelerating Effect of High Temperature in Drosophila Melanogaster. | |||
|date=01.10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25798213 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367862 | |||
}} | |||
* {{medline-title | |||
|title=Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure. | |||
|date=21.07.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25047000 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122761 | |||
}} | |||
* {{medline-title | |||
|title=Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry. | |||
|date=03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23770741 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968832 | |||
}} | |||
==CCL20== | |||
* {{medline-title | |||
|title=Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: Sex differences and role of purinergic receptors. | |||
|date=07.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33166661 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2020.11.013 | |||
}} | |||
* {{medline-title | |||
|title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272174 | |||
|full-text-url=https://sci-hub.do/10.1016/j.antiviral.2020.104784 | |||
}} | |||
* {{medline-title | |||
|title=Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29193757 | |||
|full-text-url=https://sci-hub.do/10.1002/mnfr.201700307 | |||
}} | |||
* {{medline-title | |||
|title=Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists. | |||
|date=15.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28696254 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548610 | |||
}} | |||
* {{medline-title | |||
|title=Interferon-gamma deficiency protects against aging-related goblet cell loss. | |||
|date=04.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27623073 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323102 | |||
}} | |||
* {{medline-title | |||
|title=Age dependent changes in the LPS induced transcriptome of bovine dermal fibroblasts occurs without major changes in the methylome. | |||
|date=27.01.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25623529 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312471 | |||
}} | |||
* {{medline-title | |||
|title=Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state. | |||
|date=11.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24759206 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205198 | |||
}} | |||
==CPD== | |||
* {{medline-title | |||
|title=Incidental versus clinically diagnosed differentiated thyroid cancer in both adult and elderly subjects: histological characteristics and follow-up in a retrospective analysis from a single institution. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970586 | |||
|full-text-url=https://sci-hub.do/10.1007/s12020-020-02200-z | |||
}} | |||
* {{medline-title | |||
|title=Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470706 | |||
|full-text-url=https://sci-hub.do/10.1007/s00391-018-1377-9 | |||
}} | |||
* {{medline-title | |||
|title=What Do Clinical Supervisors Require to Teach Residents in Family Medicine How to Care for Seniors? | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29310735 | |||
|full-text-url=https://sci-hub.do/10.1017/S0714980817000460 | |||
}} | |||
* {{medline-title | |||
|title=Survey of Australasian geriatricians' satisfaction with, and preferences for, continuing professional development. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27087018 | |||
|full-text-url=https://sci-hub.do/10.1111/imj.13116 | |||
}} | |||
* {{medline-title | |||
|title=The aging psychiatrist: lessons from our colleagues in surgery and anaesthesia. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912470 | |||
|full-text-url=https://sci-hub.do/10.1177/1039856216632401 | |||
}} | |||
* {{medline-title | |||
|title=Effects of donor age and proliferative aging on the phenotype stability of rat aortic smooth muscle cells. | |||
|date=11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26603458 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673651 | |||
}} | |||
* {{medline-title | |||
|title=Specificity of cytochemical and fluorescence methods of senescence-associated β-galactosidase detection for ageing driven by replication and time. | |||
|date=08.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24878779 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4090812 | |||
}} | |||
==CSF1R== | |||
* {{medline-title | |||
|title=[[CSF1R]] blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and [[RPE]] disorganization. | |||
|date=01.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32234210 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156269 | |||
}} | |||
* {{medline-title | |||
|title=[[CSF1R]] inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice. | |||
|date=02.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32007953 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041757 | |||
}} | |||
* {{medline-title | |||
|title=Modulation of Microglia by Voluntary Exercise or [[CSF1R]] Inhibition Prevents Age-Related Loss of Functional Motor Units. | |||
|date=05.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31693894 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.10.003 | |||
}} | |||
* {{medline-title | |||
|title=Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge. | |||
|date=26.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30477578 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260864 | |||
}} | |||
* {{medline-title | |||
|title=Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30276955 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260908 | |||
}} | |||
* {{medline-title | |||
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]]. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905 | |||
}} | |||
* {{medline-title | |||
|title=Pleiotropic effects of extended blockade of [[CSF1]]R signaling in adult mice. | |||
|date=08.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24652541 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378363 | |||
}} | |||
==CTSB== | |||
* {{medline-title | |||
|title=Myocardial cathepsin D is downregulated in sudden cardiac death. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32176724 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075574 | |||
}} | |||
* {{medline-title | |||
|title=A Free Radical-Generating System Regulates Amyloid Oligomers: Involvement of Cathepsin B. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400084 | |||
|full-text-url=https://sci-hub.do/10.3233/JAD-170159 | |||
}} | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
* {{medline-title | |||
|title=Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice. | |||
|date=03.04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121218 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388215 | |||
}} | |||
* {{medline-title | |||
|title=Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function. | |||
|date=09.08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27345423 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029441 | |||
}} | |||
* {{medline-title | |||
|title=The association of serum cathepsin B concentration with age-related cardiovascular-renal subclinical state in a healthy Chinese population. | |||
|date=07-08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27032082 | |||
|full-text-url=https://sci-hub.do/10.1016/j.archger.2016.03.015 | |||
}} | |||
* {{medline-title | |||
|title=Decreased serum level of [[HMGB1]] and MyD88 during human aging progress in healthy individuals. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26130428 | |||
|full-text-url=https://sci-hub.do/10.1007/s40520-015-0402-8 | |||
}} | |||
==CYP2E1== | |||
* {{medline-title | |||
|title=DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32221779 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287002 | |||
}} | |||
* {{medline-title | |||
|title=Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396457 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681801 | |||
}} | |||
* {{medline-title | |||
|title=2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. | |||
|date=01.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30939745 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479705 | |||
}} | |||
* {{medline-title | |||
|title=Neuroprotective Effect of Dioscin on the Aging Brain. | |||
|date=30.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30935017 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479446 | |||
}} | |||
* {{medline-title | |||
|title=Cytochrome P450-2E1 is involved in aging-related kidney damage in mice through increased nitroxidative stress. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28843596 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656532 | |||
}} | |||
* {{medline-title | |||
|title=Cytochrome P450-2E1 promotes aging-related hepatic steatosis, apoptosis and fibrosis through increased nitroxidative stress. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26703967 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761508 | |||
}} | |||
* {{medline-title | |||
|title=Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures. | |||
|date=25.12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25795400 | |||
|full-text-url=https://sci-hub.do/10.1016/j.tiv.2015.03.005 | |||
}} | |||
==DSP== | |||
* {{medline-title | |||
|title=Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247288 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754798 | |||
}} | |||
* {{medline-title | |||
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171 | |||
}} | |||
* {{medline-title | |||
|title=Metabolic Syndrome Components Are Associated With Symptomatic Polyneuropathy Independent of Glycemic Status. | |||
|date=05.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26965720 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839175 | |||
}} | |||
* {{medline-title | |||
|title=Analysis of diarrhetic shellfish poisoning toxins and pectenotoxin-2 in the bottlenose dolphin (Tursiops truncatus) by liquid chromatography-tandem mass spectrometry. | |||
|date=16.10.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26381568 | |||
|full-text-url=https://sci-hub.do/10.1016/j.chroma.2015.08.066 | |||
}} | |||
* {{medline-title | |||
|title=Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances. | |||
|date=15.11.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25403178 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233240 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent clinical and genetic characteristics in Japanese patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23514727 | |||
|full-text-url=https://sci-hub.do/10.1253/circj.cj-12-1446 | |||
}} | |||
* {{medline-title | |||
|title=Differences in susceptibility to okadaic acid, a diarrhetic shellfish poisoning toxin, between male and female mice. | |||
|date=27.12.2012 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23271638 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564064 | |||
}} | |||
==FIS1== | |||
* {{medline-title | |||
|title=Alterations in Mitochondrial Dynamic-related Genes in the Peripheral Blood of Alzheimer's Disease Patients. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33023448 | |||
|full-text-url=https://sci-hub.do/10.2174/1567205017666201006162538 | |||
}} | |||
* {{medline-title | |||
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. | |||
|date=01.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068 | |||
}} | |||
* {{medline-title | |||
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363 | |||
}} | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
* {{medline-title | |||
|title=Effects of β-hydroxy-β-methylbutyrate on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults. | |||
|date=01.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28705993 | |||
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00192.2017 | |||
}} | |||
* {{medline-title | |||
|title=Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27993601 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2016.12.005 | |||
}} | |||
* {{medline-title | |||
|title=Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25840089 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614869 | |||
}} | |||
==FOXP3== | |||
* {{medline-title | |||
|title=Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. | |||
|date=21.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31864349 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925900 | |||
}} | |||
* {{medline-title | |||
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663 | |||
}} | |||
* {{medline-title | |||
|title=Enhanced expression of PD-1 and other activation markers by CD4 T cells of young but not old patients with metastatic melanoma. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546435 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951899 | |||
}} | |||
* {{medline-title | |||
|title=Non-linear patterns in age-related DNA methylation may reflect [[CD4]] T cell differentiation. | |||
|date=03.06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28387568 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501198 | |||
}} | |||
* {{medline-title | |||
|title=Novel Senescent Regulatory T-Cell Subset with Impaired Suppressive Function in Rheumatoid Arthritis. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28373873 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357868 | |||
}} | |||
* {{medline-title | |||
|title=Age-related changes in CD4 CD25 [[FOXP3]] regulatory T cells and their relationship with lung cancer. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28253320 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333862 | |||
}} | |||
* {{medline-title | |||
|title=Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27190305 | |||
|full-text-url=https://sci-hub.do/10.1189/jlb.5A0116-025R | |||
}} | |||
==GAP43== | |||
* {{medline-title | |||
|title=HDAC inhibition leads to age-dependent opposite regenerative effect upon [[PTEN]] deletion in rubrospinal axons after SCI. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32171589 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.02.006 | |||
}} | |||
* {{medline-title | |||
|title=The Puzzling Role of Neuron-Specific PMCA Isoforms in the Aging Process. | |||
|date=16.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31888192 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941135 | |||
}} | |||
* {{medline-title | |||
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483 | |||
}} | |||
* {{medline-title | |||
|title=Differential expression of synaptic and interneuron genes in the aging human prefrontal cortex. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031232 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.06.011 | |||
}} | |||
* {{medline-title | |||
|title=Schwann Cell Phenotype Changes in Aging Human Dental Pulp. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28972819 | |||
|full-text-url=https://sci-hub.do/10.1177/0022034517733967 | |||
}} | |||
* {{medline-title | |||
|title=Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex. | |||
|date=01.01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28013231 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654756 | |||
}} | |||
* {{medline-title | |||
|title=Alterations of Ca²⁺-responsive proteins within cholinergic neurons in aging and Alzheimer's disease. | |||
|date=06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24461366 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961506 | |||
}} | |||
==HCN4== | |||
* {{medline-title | |||
|title=Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288034 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934612 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent down-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 4 causes deterioration of canine sinoatrial node function. | |||
|date=01.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28369243 | |||
|full-text-url=https://sci-hub.do/10.1093/abbs/gmx026 | |||
}} | |||
* {{medline-title | |||
|title=Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes. | |||
|date=11.11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379059 | |||
|full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000455 | |||
}} | |||
* {{medline-title | |||
|title=Age-associated expression of HCN channel isoforms in rat sinoatrial node. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341471 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935443 | |||
}} | |||
* {{medline-title | |||
|title=Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation. | |||
|date=09.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005035 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526032 | |||
}} | |||
* {{medline-title | |||
|title=Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. | |||
|date=27.02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761792 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352274 | |||
}} | |||
* {{medline-title | |||
|title=Association between reversal in the expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel and age-related atrial fibrillation. | |||
|date=14.11.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25404650 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242900 | |||
}} | |||
==HRAS== | |||
* {{medline-title | |||
|title=Pterostilbene Sensitizes Cisplatin-Resistant Human Bladder Cancer Cells with Oncogenic [i][[HRAS]][/i]. | |||
|date=06.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33036162 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650649 | |||
}} | |||
* {{medline-title | |||
|title=Catalog of Lung Cancer Gene Mutations Among Chinese Patients. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850378 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417348 | |||
}} | |||
* {{medline-title | |||
|title=How do combinations of unhealthy behaviors relate to attitudinal factors and subjective health among the adult population in the Netherlands? | |||
|date=03.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32245376 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126128 | |||
}} | |||
* {{medline-title | |||
|title=Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype. | |||
|date=07.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31940439 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032038 | |||
}} | |||
* {{medline-title | |||
|title="Back to the future": Influence of beliefs regarding the future on TTO answers. | |||
|date=12.01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26753687 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709901 | |||
}} | |||
* {{medline-title | |||
|title=Contributions of intrinsic mutation rate and selfish selection to levels of de novo [[HRAS]] mutations in the paternal germline. | |||
|date=10.12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24259709 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864328 | |||
}} | |||
* {{medline-title | |||
|title=PPARβ/δ promotes [[HRAS]]-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling. | |||
|date=13.11.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24213576 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017002 | |||
}} | |||
==IL2== | |||
* {{medline-title | |||
|title=Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33193368 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662090 | |||
}} | |||
* {{medline-title | |||
|title=Redox, immune and genetic biomarker system for personalized treatments in colorectal cancer. | |||
|date=15.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30788039 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379753 | |||
}} | |||
* {{medline-title | |||
|title=Low IL-2 Expressing T Cells in Thalassemia Major Patients: Is It Immune Aging. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30369736 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186253 | |||
}} | |||
* {{medline-title | |||
|title=Epigenetic repression of interleukin 2 expression in senescent CD4 T cells during chronic HIV type 1 infection. | |||
|date=01.01.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25001463 | |||
|full-text-url=https://sci-hub.do/10.1093/infdis/jiu376 | |||
}} | |||
* {{medline-title | |||
|title=Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life. | |||
|date=06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24370373 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003347 | |||
}} | |||
* {{medline-title | |||
|title=Propolis efficacy on [[TNF]]-α, IFN-γ and [[IL2]] cytokines production in old mice with and without systemic candidiasis. | |||
|date=09.2012 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23518081 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mycmed.2012.05.004 | |||
}} | |||
* {{medline-title | |||
|title=The polyfunctionality of human memory CD8 T cells elicited by acute and chronic virus infections is not influenced by age. | |||
|date=2012 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23271970 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521721 | |||
}} | |||
==KEAP1== | |||
* {{medline-title | |||
|title=Sex-, age-, and race/ethnicity-dependent variations in drug-processing and NRF2-regulated genes in human livers. | |||
|date=08.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33162398 | |||
|full-text-url=https://sci-hub.do/10.1124/dmd.120.000181 | |||
}} | |||
* {{medline-title | |||
|title=NRF2 pathway activation by [[KEAP1]] inhibition attenuates the manifestation of aging phenotypes in salivary glands. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32590331 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322188 | |||
}} | |||
* {{medline-title | |||
|title=Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds. | |||
|date=18.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424161 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234996 | |||
}} | |||
* {{medline-title | |||
|title=Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182922 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535784 | |||
}} | |||
* {{medline-title | |||
|title=Systemic overexpression of [[SQSTM1]]/p62 accelerates disease onset in a [[SOD1]] -expressing ALS mouse model. | |||
|date=29.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29843805 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975400 | |||
}} | |||
* {{medline-title | |||
|title=Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377163 | |||
|full-text-url=https://sci-hub.do/10.1111/nyas.13556 | |||
}} | |||
* {{medline-title | |||
|title=The Anti-Aging Effect of Erythropoietin via the ERK/Nrf2-ARE Pathway in Aging Rats. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28168414 | |||
|full-text-url=https://sci-hub.do/10.1007/s12031-017-0885-1 | |||
}} | |||
==LRP1== | |||
* {{medline-title | |||
|title=Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268785 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255962 | |||
}} | |||
* {{medline-title | |||
|title=LXR activation protects hippocampal microvasculature in very old triple transgenic mouse model of Alzheimer's disease. | |||
|date=16.05.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27057732 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2016.04.007 | |||
}} | |||
* {{medline-title | |||
|title=Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal [[LRP1]]. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26688581 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761336 | |||
}} | |||
* {{medline-title | |||
|title=Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats. | |||
|date=20.05.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782004 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248655 | |||
}} | |||
* {{medline-title | |||
|title=Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice. | |||
|date=10.10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25301084 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192620 | |||
}} | |||
* {{medline-title | |||
|title=[[LRP1]] protects the vasculature by regulating levels of connective tissue growth factor and HtrA1. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23868935 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892666 | |||
}} | |||
* {{medline-title | |||
|title=A lipoprotein receptor cluster IV mutant preferentially binds amyloid-β and regulates its clearance from the mouse brain. | |||
|date=24.05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23580652 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663536 | |||
}} | |||
==NOS1== | |||
* {{medline-title | |||
|title=Prepubertal overexposure to manganese induce precocious puberty through GABA receptor/nitric oxide pathway in immature female rats. | |||
|date=30.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31711775 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2019.109898 | |||
}} | |||
* {{medline-title | |||
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3 | |||
}} | |||
* {{medline-title | |||
|title=[[NOS3]] Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels. | |||
|date=11.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891729 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041791 | |||
}} | |||
* {{medline-title | |||
|title=[[NOS1]] and [[SNAP25]] polymorphisms are associated with Attention-Deficit/Hyperactivity Disorder symptoms in adults but not in children. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26821215 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2016.01.010 | |||
}} | |||
* {{medline-title | |||
|title=[[NOS1]] induces NADPH oxidases and impairs contraction kinetics in aged murine ventricular myocytes. | |||
|date=09.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26173391 | |||
|full-text-url=https://sci-hub.do/10.1007/s00395-015-0506-5 | |||
}} | |||
* {{medline-title | |||
|title=Sex-dependent hypertension and renal changes in aged rats with altered renal development. | |||
|date=15.08.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24944267 | |||
|full-text-url=https://sci-hub.do/10.1152/ajprenal.00198.2014 | |||
}} | |||
* {{medline-title | |||
|title=Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans. | |||
|date=04.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23572278 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-013-9421-z | |||
}} | |||
==NOTCH1== | |||
* {{medline-title | |||
|title=[How Does Aging Contribute to Cancer?] | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33130684 | |||
}} | |||
* {{medline-title | |||
|title=H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31609547 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778597 | |||
}} | |||
* {{medline-title | |||
|title=Age-related remodelling of oesophageal epithelia by mutated cancer drivers. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30602793 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0811-x | |||
}} | |||
* {{medline-title | |||
|title=Dynamic regulation of [[NOTCH1]] activation and Notch ligand expression in human thymus development. | |||
|date=13.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30042180 | |||
|full-text-url=https://sci-hub.do/10.1242/dev.165597 | |||
}} | |||
* {{medline-title | |||
|title=Long telomeres protect against age-dependent cardiac disease caused by [[NOTCH1]] haploinsufficiency. | |||
|date=01.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28346225 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409071 | |||
}} | |||
* {{medline-title | |||
|title=Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study. | |||
|date=09.04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27060904 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826550 | |||
}} | |||
* {{medline-title | |||
|title=Constitutive activation of [[NOTCH1]] signaling in Sertoli cells causes gonocyte exit from quiescence. | |||
|date=01.05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23391689 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630254 | |||
}} | |||
==NRAS== | |||
* {{medline-title | |||
|title=Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32558183 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669612 | |||
}} | |||
* {{medline-title | |||
|title=[[STAT3]] Relays a Differential Response to Melanoma-Associated [i][[NRAS]][/i] Mutations. | |||
|date=02.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31906480 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016650 | |||
}} | |||
* {{medline-title | |||
|title=Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study. | |||
|date=08.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31703632 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842226 | |||
}} | |||
* {{medline-title | |||
|title=Sequential acquisition of mutations in myelodysplastic syndromes. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821 | |||
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828 | |||
}} | |||
* {{medline-title | |||
|title=ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A. | |||
|date=24.03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28184004 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377799 | |||
}} | |||
* {{medline-title | |||
|title=Trametinib radiosensitises RAS- and [[BRAF]]-mutated melanoma by perturbing cell cycle and inducing senescence. | |||
|date=11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26163092 | |||
|full-text-url=https://sci-hub.do/10.1016/j.radonc.2015.06.026 | |||
}} | |||
* {{medline-title | |||
|title=Registered report: senescence surveillance of pre-malignant hepatocytes limits liver cancer development. | |||
|date=26.01.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25621566 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383234 | |||
}} | |||
==NTS== | |||
* {{medline-title | |||
|title=Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140326 | |||
|full-text-url=https://sci-hub.do/10.1080/07420528.2019.1613424 | |||
}} | |||
* {{medline-title | |||
|title=Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518407 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019141 | |||
}} | |||
* {{medline-title | |||
|title=Neural processing of basic tastes in healthy young and older adults - an fMRI study. | |||
|date=01.10.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26072251 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neuroimage.2015.06.017 | |||
}} | |||
* {{medline-title | |||
|title=Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity. | |||
|date=05.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25636077 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424182 | |||
}} | |||
* {{medline-title | |||
|title=Endogenous leptin contributes to baroreflex suppression within the solitary tract nucleus of aged rats. | |||
|date=01.12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25260611 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255011 | |||
}} | |||
* {{medline-title | |||
|title=Central hydrogen sulphide mediates ventilatory responses to hypercapnia in adult conscious rats. | |||
|date=11.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25042027 | |||
|full-text-url=https://sci-hub.do/10.1111/apha.12346 | |||
}} | |||
* {{medline-title | |||
|title=Chronic intermittent hypoxia promotes expression of 3-mercaptopyruvate sulfurtransferase in adult rat medulla oblongata. | |||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24051007 | |||
|full-text-url=https://sci-hub.do/10.1016/j.autneu.2013.08.066 | |||
}} | |||
==OGT== | |||
* {{medline-title | |||
|title=ELT-2 promotes O-GlcNAc transferase [[OGT]]-1 expression to modulate Caenorhabditis elegans lifespan. | |||
|date=06.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32628333 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.29817 | |||
}} | |||
* {{medline-title | |||
|title=Neuronal O-GlcNAcylation Improves Cognitive Function in the Aged Mouse Brain. | |||
|date=21.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31588002 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199460 | |||
}} | |||
* {{medline-title | |||
|title=Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor [[JUN]]. | |||
|date=31.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30012597 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077742 | |||
}} | |||
* {{medline-title | |||
|title=O-GlcNAcylation of SKN-1 modulates the lifespan and oxidative stress resistance in Caenorhabditis elegans. | |||
|date=08.03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28272406 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341102 | |||
}} | |||
* {{medline-title | |||
|title=O-linked N-acetylglucosamine transferase ([[OGT]]) interacts with the histone chaperone [[HIRA]] complex and regulates nucleosome assembly and cellular senescence. | |||
|date=07.06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27217568 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988580 | |||
}} | |||
* {{medline-title | |||
|title=Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure. | |||
|date=22.12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26673325 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839001 | |||
}} | |||
* {{medline-title | |||
|title=[[OGT]] and [[OGA]] expression in postmenopausal skeletal muscle associates with hormone replacement therapy and muscle cross-sectional area. | |||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24365779 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2013.10.007 | |||
}} | |||
==P2RY12== | |||
* {{medline-title | |||
|title=Potential caveats of putative microglia-specific markers for assessment of age-related cerebrovascular neuroinflammation. | |||
|date=01.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33261619 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709276 | |||
}} | |||
* {{medline-title | |||
|title=Microglial changes in the early aging stage in a healthy retina and an experimental glaucoma model. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32958210 | |||
|full-text-url=https://sci-hub.do/10.1016/bs.pbr.2020.05.024 | |||
}} | |||
* {{medline-title | |||
|title=Patterns of Expression of Purinergic Receptor [[P2RY12]], a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains. | |||
|date=20.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31968618 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014248 | |||
}} | |||
* {{medline-title | |||
|title=Age Influences Microglial Activation After Cuprizone-Induced Demyelination. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297998 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160739 | |||
}} | |||
* {{medline-title | |||
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z | |||
}} | |||
* {{medline-title | |||
|title=Transcriptomic analysis of purified human cortical microglia reveals age-associated changes. | |||
|date=08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28671693 | |||
|full-text-url=https://sci-hub.do/10.1038/nn.4597 | |||
}} | |||
* {{medline-title | |||
|title=Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis. | |||
|date=01.07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28541408 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057548 | |||
}} | |||
==PCSK9== | |||
* {{medline-title | |||
|title=Lipoprotein removal mechanisms and aging: implications for the cardiovascular health of the elderly. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32011347 | |||
|full-text-url=https://sci-hub.do/10.1097/MED.0000000000000529 | |||
}} | |||
* {{medline-title | |||
|title=The role of proprotein convertase subtilisin-kexin type 9 ([[PCSK9]]) in the vascular aging process - is there a link? | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31708986 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836637 | |||
}} | |||
* {{medline-title | |||
|title=[[PCSK9]] Inhibitors Show Value for Patients and the US Health Care System. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29241886 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929151 | |||
}} | |||
* {{medline-title | |||
|title=Association between lipoprotein (a) and proprotein convertase substilisin/kexin type 9 in patients with heterozygous familial hypercholesterolemia: A case-control study. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129821 | |||
|full-text-url=https://sci-hub.do/10.1016/j.metabol.2017.11.004 | |||
}} | |||
* {{medline-title | |||
|title=What's next for dyslipidemia management? The 2013 ACC/AHA Guidelines, the NLA recommendations, and beyond. | |||
|date=05-06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27156942 | |||
|full-text-url=https://sci-hub.do/10.1016/j.japh.2015.12.017 | |||
}} | |||
* {{medline-title | |||
|title=Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice. | |||
|date=15.01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26592663 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.11.064 | |||
}} | |||
* {{medline-title | |||
|title=[[[[PC]]SK9]]: a key modulator of cardiovascular health. | |||
|date=14.03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24625727 | |||
|full-text-url=https://sci-hub.do/10.1161/CIRCRESAHA.114.301621 | |||
}} | |||
==PIK3CA== | |||
* {{medline-title | |||
|title=Catalog of Lung Cancer Gene Mutations Among Chinese Patients. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850378 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417348 | |||
}} | |||
* {{medline-title | |||
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway. | |||
|date=10.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820 | |||
}} | |||
* {{medline-title | |||
|title=Oncogenic mutations in histologically normal endometrium: the new normal? | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483 | |||
|full-text-url=https://sci-hub.do/10.1002/path.5314 | |||
}} | |||
* {{medline-title | |||
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125 | |||
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7 | |||
}} | |||
* {{medline-title | |||
|title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]] accompanied with pro-tumorigenic secretome. | |||
|date=01.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946 | |||
|full-text-url=https://sci-hub.do/10.1002/ijc.32153 | |||
}} | |||
* {{medline-title | |||
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 | |||
}} | |||
* {{medline-title | |||
|title=Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26168237 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500567 | |||
}} | |||
==PYY== | |||
* {{medline-title | |||
|title=Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31400786 | |||
|full-text-url=https://sci-hub.do/10.1016/j.pestbp.2019.05.018 | |||
}} | |||
* {{medline-title | |||
|title=Peptide YY ([[PYY]]) Is Expressed in Human Skeletal Muscle Tissue and Expanding Human Muscle Progenitor Cells. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890955 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412030 | |||
}} | |||
* {{medline-title | |||
|title=Peptide YY induces characteristic meal patterns of aged mice. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28916138 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yhbeh.2017.09.003 | |||
}} | |||
* {{medline-title | |||
|title=Effects of randomized whey-protein loads on energy intake, appetite, gastric emptying, and plasma gut-hormone concentrations in older men and women. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28747330 | |||
|full-text-url=https://sci-hub.do/10.3945/ajcn.117.154377 | |||
}} | |||
* {{medline-title | |||
|title=Glucagon-like peptide-1 (GLP-1) increases in plasma and colon tissue prior to estrus and circulating levels change with increasing age in reproductively competent Wistar rats. | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28237410 | |||
|full-text-url=https://sci-hub.do/10.1016/j.peptides.2017.02.010 | |||
}} | |||
* {{medline-title | |||
|title=Increased peptide YY blood concentrations, not decreased acyl-ghrelin, are associated with reduced hunger and food intake in healthy older women: Preliminary evidence. | |||
|date=01.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27264721 | |||
|full-text-url=https://sci-hub.do/10.1016/j.appet.2016.06.002 | |||
}} | |||
* {{medline-title | |||
|title=Anorexigenic postprandial responses of [[PYY]] and GLP1 to slow ice cream consumption: preservation in obese adolescents, but not in obese adults. | |||
|date=03.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23239758 | |||
|full-text-url=https://sci-hub.do/10.1530/EJE-12-0867 | |||
}} | |||
==RIPK3== | |||
* {{medline-title | |||
|title=Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. | |||
|date=18.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33206046 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673785 | |||
}} | |||
* {{medline-title | |||
|title=Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31981738 | |||
|full-text-url=https://sci-hub.do/10.1016/j.joca.2020.01.004 | |||
}} | |||
* {{medline-title | |||
|title=Metformin mediates cardioprotection against aging-induced ischemic necroptosis. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31944526 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996959 | |||
}} | |||
* {{medline-title | |||
|title=A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice. | |||
|date=12.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862818 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414664 | |||
}} | |||
* {{medline-title | |||
|title=RIP kinases as modulators of inflammation and immunity. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615 | |||
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x | |||
}} | |||
* {{medline-title | |||
|title=Necroptosis increases with age and is reduced by dietary restriction. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696779 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052392 | |||
}} | |||
* {{medline-title | |||
|title=[[RIPK1]]-[[RIPK3]]-[[MLKL]]-dependent necrosis promotes the aging of mouse male reproductive system. | |||
|date=15.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807105 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557593 | |||
}} | |||
==ROCK1== | |||
* {{medline-title | |||
|title=Disruption of both [[ROCK1]] and [[ROCK2]] genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30848941 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529334 | |||
}} | |||
* {{medline-title | |||
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483 | |||
}} | |||
* {{medline-title | |||
|title=Vascular Smooth Muscle Contractile Function Declines With Age in Skeletal Muscle Feed Arteries. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30108507 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079263 | |||
}} | |||
* {{medline-title | |||
|title=Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1. | |||
|date=01-02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27678468 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227678 | |||
}} | |||
* {{medline-title | |||
|title=Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis. | |||
|date=14.01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26765561 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798951 | |||
}} | |||
* {{medline-title | |||
|title=Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle. | |||
|date=15.10.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26468005 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606542 | |||
}} | |||
* {{medline-title | |||
|title=miR-135a modulates tendon stem/progenitor cell senescence via suppressing [[ROCK1]]. | |||
|date=02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25460182 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bone.2014.11.001 | |||
}} | |||
==RUNX1== | |||
* {{medline-title | |||
|title=RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing [[RUNX1]] fusion oncoproteins. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29052866 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813226 | |||
}} | |||
* {{medline-title | |||
|title=Sequential acquisition of mutations in myelodysplastic syndromes. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821 | |||
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828 | |||
}} | |||
* {{medline-title | |||
|title=Conversion of adult endothelium to immunocompetent haematopoietic stem cells. | |||
|date=25.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28514438 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794215 | |||
}} | |||
* {{medline-title | |||
|title=Resistance Training Enhances Skeletal Muscle Innervation Without Modifying the Number of Satellite Cells or their Myofiber Association in Obese Older Adults. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26447161 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018557 | |||
}} | |||
* {{medline-title | |||
|title=Epigenetic Aging Signatures Are Coherently Modified in Cancer. | |||
|date=06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26110659 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482318 | |||
}} | |||
* {{medline-title | |||
|title=Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex. | |||
|date=08.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26002684 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503803 | |||
}} | |||
* {{medline-title | |||
|title=Runx3 deficiency results in myeloproliferative disorder in aged mice. | |||
|date=25.07.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23741011 | |||
|full-text-url=https://sci-hub.do/10.1182/blood-2012-10-460618 | |||
}} | |||
==SET== | |||
* {{medline-title | |||
|title=Two conserved epigenetic regulators prevent healthy ageing. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32103178 | |||
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2037-y | |||
}} | |||
* {{medline-title | |||
|title=Chromatin Modifiers [[SET]]-25 and [[SET]]-32 Are Required for Establishment but Not Long-Term Maintenance of Transgenerational Epigenetic Inheritance. | |||
|date=20.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463020 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.10.085 | |||
}} | |||
* {{medline-title | |||
|title=[[SET]]-9 and [[SET]]-26 are H3K4me3 readers and play critical roles in germline development and longevity. | |||
|date=01.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29714684 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010342 | |||
}} | |||
* {{medline-title | |||
|title=Muscle-Specific Histone H3K36 Dimethyltransferase [[SET]]-18 Shortens Lifespan of Caenorhabditis elegans by Repressing daf-16a Expression. | |||
|date=06.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29514099 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.02.029 | |||
}} | |||
* {{medline-title | |||
|title=Assessing efficacy of day 3 embryo time-lapse algorithms retrospectively: impacts of dataset type and confounding factors. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338469 | |||
|full-text-url=https://sci-hub.do/10.1080/14647273.2018.1425919 | |||
}} | |||
* {{medline-title | |||
|title=CONSTANCES: a general prospective population-based cohort for occupational and environmental epidemiology: cohort profile. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27884936 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241503 | |||
}} | |||
* {{medline-title | |||
|title=A non-canonical role for the C. elegans dosage compensation complex in growth and metabolic regulation downstream of TOR complex 2. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23884442 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742143 | |||
}} | |||
==SLA== | |||
* {{medline-title | |||
|title=Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity. | |||
|date=14.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32540272 | |||
|full-text-url=https://sci-hub.do/10.1016/j.vaccine.2020.05.085 | |||
}} | |||
* {{medline-title | |||
|title=Mechanical Anisotropy and Surface Roughness in Additively Manufactured Parts Fabricated by Stereolithography ([[SLA]]) Using Statistical Analysis. | |||
|date=30.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32486137 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321476 | |||
}} | |||
* {{medline-title | |||
|title=The Effect of Age of Titanium Dental Implants on Implant Survival and Marginal Bone Resorption: A 5-Year Retrospective Follow-Up Study. | |||
|date=01.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32369581 | |||
|full-text-url=https://sci-hub.do/10.1563/aaid-joi-D-19-00316 | |||
}} | |||
* {{medline-title | |||
|title="Spirometric" lung age reference equations: A narrative review. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28870870 | |||
|full-text-url=https://sci-hub.do/10.1016/j.resp.2017.08.018 | |||
}} | |||
* {{medline-title | |||
|title=Relative growth rate in phylogenetically related deciduous and evergreen woody species. | |||
|date=07.2001 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28547465 | |||
|full-text-url=https://sci-hub.do/10.1007/s004420100645 | |||
}} | |||
* {{medline-title | |||
|title=Leaf lifespan as a determinant of leaf structure and function among 23 amazonian tree species. | |||
|date=03.1991 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28313152 | |||
|full-text-url=https://sci-hub.do/10.1007/BF00317383 | |||
}} | |||
* {{medline-title | |||
|title=The Performance of Titanium-Zirconium Implants in the Elderly: A Biomechanical Comparative Study in the Minipig. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26834004 | |||
|full-text-url=https://sci-hub.do/10.1111/cid.12389 | |||
}} | |||
==SLC6A4== | |||
* {{medline-title | |||
|title=The Psilocybin-Telomere Hypothesis: An empirically falsifiable prediction concerning the beneficial neuropsychopharmacological effects of psilocybin on genetic aging. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31634774 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2019.109406 | |||
}} | |||
* {{medline-title | |||
|title=Epigenetics-by-sex interaction for somatization conferred by methylation at the promoter region of [[SLC6A4]] gene. | |||
|date=08.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30201454 | |||
|full-text-url=https://sci-hub.do/10.1016/j.pnpbp.2018.09.002 | |||
}} | |||
* {{medline-title | |||
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392 | |||
}} | |||
* {{medline-title | |||
|title=DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor ([[BDNF]]) and oxytocin receptor ([[OXTR]]) genes are associated with anxiety/depression in older women. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26175754 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485183 | |||
}} | |||
* {{medline-title | |||
|title=Role of the serotonin transporter gene locus in the response to SSRI treatment of major depressive disorder in late life. | |||
|date=05.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25827644 | |||
|full-text-url=https://sci-hub.do/10.1177/0269881115578159 | |||
}} | |||
* {{medline-title | |||
|title=The Impact of Genetics on Physical Resilience and Successful Aging. | |||
|date=09.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25818147 | |||
|full-text-url=https://sci-hub.do/10.1177/0898264315577586 | |||
}} | |||
* {{medline-title | |||
|title=Serotonin transporter polymorphism modifies the association between depressive symptoms and sleep onset latency complaint in elderly people: results from the 'InveCe.Ab' study. | |||
|date=04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25297871 | |||
|full-text-url=https://sci-hub.do/10.1111/jsr.12248 | |||
}} | |||
==SRC== | |||
* {{medline-title | |||
|title=Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. | |||
|date=18.08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32811819 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434891 | |||
}} | |||
* {{medline-title | |||
|title=Metabolic characteristics of CD8 T cell subsets in young and aged individuals are not predictive of functionality. | |||
|date=05.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32504069 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275080 | |||
}} | |||
* {{medline-title | |||
|title=Overexpression of steroid receptor coactivators alleviates hyperglycemia-induced endothelial cell injury in rats through activating the PI3K/Akt pathway. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30089865 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786429 | |||
}} | |||
* {{medline-title | |||
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201 | |||
}} | |||
* {{medline-title | |||
|title=Genetic and Environmental Models of Circadian Disruption Link [[SRC]]-2 Function to Hepatic Pathology. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27432117 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248931 | |||
}} | |||
* {{medline-title | |||
|title=Conflict-Specific Aging Effects Mainly Manifest in Early Information Processing Stages-An ERP Study with Different Conflict Types. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27014059 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792879 | |||
}} | |||
* {{medline-title | |||
|title=Investigating the stability of mcDESPOT myelin water fraction values derived using a stochastic region contraction approach. | |||
|date=01.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24464472 | |||
|full-text-url=https://sci-hub.do/10.1002/mrm.25108 | |||
}} | |||
==SRM== | |||
* {{medline-title | |||
|title=[Geriatric specificities of localized renal cell carcinoma]. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771769 | |||
|full-text-url=https://sci-hub.do/10.1016/j.purol.2019.08.281 | |||
}} | |||
* {{medline-title | |||
|title=A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes. | |||
|date=08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28508553 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863538 | |||
}} | |||
* {{medline-title | |||
|title=The effect of tone-vocoding on spatial release from masking for old, hearing-impaired listeners. | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28464637 | |||
|full-text-url=https://sci-hub.do/10.1121/1.4979593 | |||
}} | |||
* {{medline-title | |||
|title=The role of early and late reflections on spatial release from masking: Effects of age and hearing loss. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28372125 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392074 | |||
}} | |||
* {{medline-title | |||
|title=Cortical Measures of Binaural Processing Predict Spatial Release from Masking Performance. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28377706 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359282 | |||
}} | |||
* {{medline-title | |||
|title=Release from masking for small spatial separations: Effects of age and hearing loss. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27475216 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392088 | |||
}} | |||
* {{medline-title | |||
|title=Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes. | |||
|date=01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26577303 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853592 | |||
}} | |||
==TAT== | |||
* {{medline-title | |||
|title=Screening for a suitable cell membrane anchoring tag for Pseudomonas aeruginosa and applying it in cell membrane real-time tracking to investigate membrane aging. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32561163 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mimet.2020.105984 | |||
}} | |||
* {{medline-title | |||
|title=Internalization of the [[TAT]]-[[PBX1]] fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence. | |||
|date=10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436118 | |||
|full-text-url=https://sci-hub.do/10.1007/s10529-020-02909-x | |||
}} | |||
* {{medline-title | |||
|title=Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31024341 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467974 | |||
}} | |||
* {{medline-title | |||
|title=Effects of HIV-1 gp120 and [[TAT]]-derived microvesicles on endothelial cell function. | |||
|date=01.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789287 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589811 | |||
}} | |||
* {{medline-title | |||
|title=Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation. | |||
|date=05.01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28055018 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386354 | |||
}} | |||
* {{medline-title | |||
|title=Characteristics, tissue-specific expression, and hormonal regulation of expression of tyrosine aminotransferase in the avian female reproductive tract. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27295280 | |||
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2016.05.001 | |||
}} | |||
* {{medline-title | |||
|title=Nanog induces suppression of senescence through downregulation of p27KIP1 expression. | |||
|date=01.03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26795560 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813312 | |||
}} | |||
==TPP1== | |||
* {{medline-title | |||
|title=[[TPP1]] Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the [[MRE11]]/AKT Pathway. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33195247 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658181 | |||
}} | |||
* {{medline-title | |||
|title=FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping. | |||
|date=03.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33086033 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2020.10.004 | |||
}} | |||
* {{medline-title | |||
|title=Gemfibrozil, food and drug administration-approved lipid-lowering drug, increases longevity in mouse model of late infantile neuronal ceroid lipofuscinosis. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199020 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395327 | |||
}} | |||
* {{medline-title | |||
|title=Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27559927 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248966 | |||
}} | |||
* {{medline-title | |||
|title=Increased expression of telomere-regulating genes in endurance athletes with long leukocyte telomeres. | |||
|date=15.01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26586905 | |||
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00587.2015 | |||
}} | |||
* {{medline-title | |||
|title=[[SIRT1]] ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24917814 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042159 | |||
}} | |||
* {{medline-title | |||
|title=Essential role for the TRF2 telomere protein in adult skin homeostasis. | |||
|date=08.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24725274 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326939 | |||
}} | |||
==TRIM59== | |||
* {{medline-title | |||
|title=DNA methylation of the [[ELOVL2]], [[FHL2]], [[KLF14]], C1orf132/MIR29B2C, and [[TRIM59]] genes for age prediction from blood, saliva, and buccal swab samples. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30300865 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010 | |||
}} | |||
* {{medline-title | |||
|title=Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30031222 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.07.007 | |||
}} | |||
* {{medline-title | |||
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015 | |||
}} | |||
* {{medline-title | |||
|title=DNA methylation in [[ELOVL2]] and C1orf132 correctly predicted chronological age of individuals from three disease groups. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28725932 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748441 | |||
}} | |||
* {{medline-title | |||
|title=Independent validation of DNA-based approaches for age prediction in blood. | |||
|date=07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28511095 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.04.020 | |||
}} | |||
* {{medline-title | |||
|title=Donor age and C1orf132/MIR29B2C determine age-related methylation signature of blood after allogeneic hematopoietic stem cell transplantation. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27602173 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012039 | |||
}} | |||
* {{medline-title | |||
|title=Development of a forensically useful age prediction method based on DNA methylation analysis. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26026729 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2015.05.001 | |||
}} | |||
==TSC1== | |||
* {{medline-title | |||
|title=[i]Tsc1[/i] Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells. | |||
|date=10.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32927859 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565438 | |||
}} | |||
* {{medline-title | |||
|title=mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30924297 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516169 | |||
}} | |||
* {{medline-title | |||
|title=[[FTO]] is involved in Alzheimer's disease by targeting [[TSC1]]-mTOR-Tau signaling. | |||
|date=25.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501742 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.02.201 | |||
}} | |||
* {{medline-title | |||
|title=Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29023667 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716871 | |||
}} | |||
* {{medline-title | |||
|title=Moderate lifelong overexpression of tuberous sclerosis complex 1 ([[TSC1]]) improves health and survival in mice. | |||
|date=11.04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28400571 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429778 | |||
}} | |||
* {{medline-title | |||
|title=mTOR inactivation by ROS-JNK-p53 pathway plays an essential role in psedolaric acid B induced autophagy-dependent senescence in murine fibrosarcoma L929 cells. | |||
|date=05.09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23810968 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2013.05.051 | |||
}} | |||
* {{medline-title | |||
|title=Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23744272 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759338 | |||
}} | |||
==UCP3== | |||
* {{medline-title | |||
|title=Altered miRNA and mRNA Expression in Sika Deer Skeletal Muscle with Age. | |||
|date=06.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32041309 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073773 | |||
}} | |||
* {{medline-title | |||
|title=Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice. | |||
|date=05.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31806023 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896328 | |||
}} | |||
* {{medline-title | |||
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001 | |||
}} | |||
* {{medline-title | |||
|title=Pleiotropic effects of [[UCP2]]-[[UCP3]] variability on leucocyte telomere length and glucose homeostasis. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28281015 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9690-z | |||
}} | |||
* {{medline-title | |||
|title=Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes [[UCP2]] and [[UCP3]] affect mitochondrial metabolism and healthy aging in female nonagenarians. | |||
|date=08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26965008 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935613 | |||
}} | |||
* {{medline-title | |||
|title=[Genotype and allele frequencies of UCP and PPAR gene families in residents of besieged Leningrad and in the control group]. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25826986 | |||
}} | |||
* {{medline-title | |||
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201 | |||
}} | |||
==XPC== | |||
* {{medline-title | |||
|title=MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene [[XPC]] in Age-related Cataract. | |||
|date=12.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30315181 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185952 | |||
}} | |||
* {{medline-title | |||
|title=Global-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo Modifiers. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27200078 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848295 | |||
}} | |||
* {{medline-title | |||
|title=Xeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulation. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26521083 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713717 | |||
}} | |||
* {{medline-title | |||
|title=Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes. | |||
|date=19.10.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26477511 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609912 | |||
}} | |||
* {{medline-title | |||
|title=[Role of DNA repair genes in radiation-induced changes of lifespan of Drosophila melanogaster]. | |||
|date=09-10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25775840 | |||
}} | |||
* {{medline-title | |||
|title=Defective mitophagy in [[XPA]] via PARP-1 hyperactivation and NAD( )/[[SIRT1]] reduction. | |||
|date=08.05.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24813611 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625837 | |||
}} | |||
* {{medline-title | |||
|title=Postprandial activation of p53-dependent DNA repair is modified by Mediterranean diet supplemented with coenzyme Q10 in elderly subjects. | |||
|date=07.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24158762 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/glt174 | |||
}} | |||
==ABCA7== | |||
* {{medline-title | |||
|title=New genetic players in late-onset Alzheimer's disease: Findings of genome-wide association studies. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30381536 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206761 | |||
}} | |||
* {{medline-title | |||
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort. | |||
|date=16.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723 | |||
}} | |||
* {{medline-title | |||
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. | |||
|date=28.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389 | |||
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049 | |||
}} | |||
* {{medline-title | |||
|title=Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28269768 | |||
|full-text-url=https://sci-hub.do/10.3233/JAD-160774 | |||
}} | |||
* {{medline-title | |||
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. | |||
|date=11.04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828 | |||
}} | |||
* {{medline-title | |||
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889 | |||
}} | |||
==ADAM17== | |||
* {{medline-title | |||
|title=[[ACE2]]/[[ADAM17]]/[[TMPRSS2]] Interplay May Be the Main Risk Factor for COVID-19. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575774 | |||
}} | |||
* {{medline-title | |||
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. | |||
|date=25.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387 | |||
}} | |||
* {{medline-title | |||
|title=Role of Adipose Tissue Endothelial [[ADAM17]] in Age-Related Coronary Microvascular Dysfunction. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28473444 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484536 | |||
}} | |||
* {{medline-title | |||
|title=Selective Inhibition of [[ADAM17]] Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28297575 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442763 | |||
}} | |||
* {{medline-title | |||
|title=[The effect of PNS on the content and activity of alpha-secretase in the brains of SAMP8 mice with alzheimer's disease]. | |||
|date=11.2012 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23627094 | |||
}} | |||
* {{medline-title | |||
|title=Endothelial deletion of [[ADAM17]] in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. | |||
|date=04-05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23354118 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622831 | |||
}} | |||
==AFP== | |||
* {{medline-title | |||
|title=Effect of Alpha-Fetoprotein on Lifespan of Old Mice. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28259124 | |||
|full-text-url=https://sci-hub.do/10.1134/S0006297916120087 | |||
}} | |||
* {{medline-title | |||
|title=Correlation between vitamin D levels and apoptosis in geriatric patients infected with hepatitis C virus genotype 4. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27217734 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862759 | |||
}} | |||
* {{medline-title | |||
|title=A new paradigm about HERV-K102 particle production and blocked release to explain cortisol mediated immunosenescence and age-associated risk of chronic disease. | |||
|date=12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26760982 | |||
}} | |||
* {{medline-title | |||
|title=Are Performance Measures Necessary to Predict Loss of Independence in Elderly People? | |||
|date=01.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26273019 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715230 | |||
}} | |||
* {{medline-title | |||
|title=Proteomic biomarkers for ageing the mosquito Aedes aegypti to determine risk of pathogen transmission. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23536806 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594161 | |||
}} | |||
* {{medline-title | |||
|title=Effect of vocal nerve section on song and ZENK protein expression in area X in adult male zebra finches. | |||
|date=2012 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23251821 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515940 | |||
}} | |||
==AMT== | |||
* {{medline-title | |||
|title=A multi-method comparison of autobiographical memory impairments amongst younger and older adults. | |||
|date=12.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162531 | |||
|full-text-url=https://sci-hub.do/10.1080/13607863.2020.1729338 | |||
}} | |||
* {{medline-title | |||
|title=Autobiographical Memory From Different Life Stages in Individuals With Obstructive Sleep Apnea. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696518 | |||
|full-text-url=https://sci-hub.do/10.1017/S1355617718001091 | |||
}} | |||
* {{medline-title | |||
|title=Fatigue in Younger and Older Drivers: Effectiveness of an Alertness-Maintaining Task. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28510495 | |||
|full-text-url=https://sci-hub.do/10.1177/0018720817706811 | |||
}} | |||
* {{medline-title | |||
|title=Reduced specificity and enhanced subjective experience of future thinking in ageing: the influence of avoidance and emotion-regulation strategies. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28470139 | |||
|full-text-url=https://sci-hub.do/10.1080/09658211.2017.1322108 | |||
}} | |||
* {{medline-title | |||
|title=Evaluation of delirium screening tools in geriatric medical inpatients: a diagnostic test accuracy study. | |||
|date=11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27503794 | |||
|full-text-url=https://sci-hub.do/10.1093/ageing/afw130 | |||
}} | |||
* {{medline-title | |||
|title=Falls and other geriatric syndromes in Blantyre, Malawi: a community survey of older adults. | |||
|date=12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26167258 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325343 | |||
}} | |||
==AQP1== | |||
* {{medline-title | |||
|title=Blue Light Induces Down-Regulation of Aquaporin 1, 3, and 9 in Human Keratinocytes. | |||
|date=03.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400272 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262559 | |||
}} | |||
* {{medline-title | |||
|title=[Age-related changes of water transport by corneal endothelial cells in rats.] | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322730 | |||
}} | |||
* {{medline-title | |||
|title=Investigation of the effects of aging on the expression of aquaporin 1 and aquaporin 4 protein in heart tissue. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27443479 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324856 | |||
}} | |||
* {{medline-title | |||
|title=Seasonal and Ageing-Depending Changes of Aquaporins 1 and 9 Expression in the Genital Tract of Buffalo Bulls (Bubalus bubalis). | |||
|date=08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27260501 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.12713 | |||
}} | |||
* {{medline-title | |||
|title=Investigation of age-related changes in the expression of aquaporin-1 and aquaporin-5 in the salivary glands of mice. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27067150 | |||
|full-text-url=https://sci-hub.do/10.3109/00016489.2016.1165353 | |||
}} | |||
* {{medline-title | |||
|title=The effects of high doses of nandrolone decanoate and exercise on prostate microvasculature of adult and older rats. | |||
|date=15.01.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25447446 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2014.11.006 | |||
}} | |||
==ASPA== | |||
* {{medline-title | |||
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637 | |||
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006 | |||
}} | |||
* {{medline-title | |||
|title=Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27337627 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2016.06.005 | |||
}} | |||
* {{medline-title | |||
|title=Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures. | |||
|date=05.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27249102 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931852 | |||
}} | |||
* {{medline-title | |||
|title=Plasma Amyloid Beta 1-42 and DNA Methylation Pattern Predict Accelerated Aging in Young Subjects with Down Syndrome. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27234618 | |||
|full-text-url=https://sci-hub.do/10.1007/s12017-016-8413-y | |||
}} | |||
* {{medline-title | |||
|title=Developing a DNA methylation assay for human age prediction in blood and bloodstain. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25979242 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2015.05.007 | |||
}} | |||
* {{medline-title | |||
|title=Aging of blood can be tracked by DNA methylation changes at just three CpG sites. | |||
|date=03.02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24490752 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053864 | |||
}} | |||
==BID== | |||
* {{medline-title | |||
|title=Dabigatran etexilate: appropriate use in patients with chronic kidney disease and in the elderly patients. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28439778 | |||
|full-text-url=https://sci-hub.do/10.1007/s11739-017-1660-6 | |||
}} | |||
* {{medline-title | |||
|title=Sperm-associated antigen 9 ([[SPAG9]]) promotes the survival and tumor growth of triple-negative breast cancer cells. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27449044 | |||
|full-text-url=https://sci-hub.do/10.1007/s13277-016-5240-6 | |||
}} | |||
* {{medline-title | |||
|title=Rationale for the Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects Trial (POST5). | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26995374 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ahj.2016.01.017 | |||
}} | |||
* {{medline-title | |||
|title=The geriatric mania asenapine study (GeMS). | |||
|date=05-06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26952385 | |||
|full-text-url=https://sci-hub.do/10.1016/j.archger.2016.01.012 | |||
}} | |||
* {{medline-title | |||
|title=The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25910621 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854160 | |||
}} | |||
* {{medline-title | |||
|title=Neuroimmunomodulation and aging: a role for transferrin and the hypothalamus/thymus axis. | |||
|date=02.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23895519 | |||
|full-text-url=https://sci-hub.do/10.2174/1874609811306010004 | |||
}} | |||
==BMF== | |||
* {{medline-title | |||
|title=Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. | |||
|date=13.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31935369 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146079 | |||
}} | |||
* {{medline-title | |||
|title=lncRNA-ES3/miR-34c-5p/[[BMF]] axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs. | |||
|date=17.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654331 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366973 | |||
}} | |||
* {{medline-title | |||
|title=Aging, hematopoiesis, and the myelodysplastic syndromes. | |||
|date=08.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29222239 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142578 | |||
}} | |||
* {{medline-title | |||
|title=Bone marrow fat unsaturation in young adults is not affected by present or childhood obesity, but increases with age: A pilot study. | |||
|date=11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26388537 | |||
|full-text-url=https://sci-hub.do/10.1016/j.metabol.2015.08.014 | |||
}} | |||
* {{medline-title | |||
|title=Loss of the proapoptotic BH3-only protein BCL-2 modifying factor prolongs the fertile life span in female mice. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24571986 | |||
|full-text-url=https://sci-hub.do/10.1095/biolreprod.113.116947 | |||
}} | |||
* {{medline-title | |||
|title=Comparison of vertebral bone marrow fat assessed by 1H MRS and inphase and out-of-phase MRI among family members. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23943163 | |||
|full-text-url=https://sci-hub.do/10.1007/s00198-013-2472-9 | |||
}} | |||
==BMP15== | |||
* {{medline-title | |||
|title=Prediction of ovarian aging using ovarian expression of [[BMP15]], [[GDF9]], and C-[[KIT]]. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223330 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221484 | |||
}} | |||
* {{medline-title | |||
|title=Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31389140 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826128 | |||
}} | |||
* {{medline-title | |||
|title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012 | |||
|full-text-url=https://sci-hub.do/10.1002/mrd.23079 | |||
}} | |||
* {{medline-title | |||
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. | |||
|date=18.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463 | |||
}} | |||
* {{medline-title | |||
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490 | |||
|full-text-url=https://sci-hub.do/10.1071/RD14472 | |||
}} | |||
* {{medline-title | |||
|title=Interactions between genetic variants in [[AMH]] and [[[[AMH]]R2]] may modify age at natural menopause. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23544102 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609726 | |||
}} | |||
==BRD4== | |||
* {{medline-title | |||
|title=Inhibition of [[BRD4]] triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells. | |||
|date=20.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32954665 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701500 | |||
}} | |||
* {{medline-title | |||
|title=[[BRD4]] contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake. | |||
|date=11.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32392533 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288959 | |||
}} | |||
* {{medline-title | |||
|title=BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes. | |||
|date=26.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31561444 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801956 | |||
}} | |||
* {{medline-title | |||
|title=Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence. | |||
|date=01.10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31265875 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159039 | |||
}} | |||
* {{medline-title | |||
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008 | |||
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004 | |||
}} | |||
* {{medline-title | |||
|title=Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases. | |||
|date=04.11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27650498 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095428 | |||
}} | |||
==CCR6== | |||
* {{medline-title | |||
|title=Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696983 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474 | |||
}} | |||
* {{medline-title | |||
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. | |||
|date=19.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985 | |||
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052 | |||
}} | |||
* {{medline-title | |||
|title=Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27190305 | |||
|full-text-url=https://sci-hub.do/10.1189/jlb.5A0116-025R | |||
}} | |||
* {{medline-title | |||
|title=Double negative (IgG IgD-CD27-) B cells are increased in a cohort of moderate-severe Alzheimer's disease patients and show a pro-inflammatory trafficking receptor phenotype. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25408215 | |||
|full-text-url=https://sci-hub.do/10.3233/JAD-142412 | |||
}} | |||
* {{medline-title | |||
|title=Trafficking phenotype and production of granzyme B by double negative B cells (IgG( )IgD(-)CD27(-)) in the elderly. | |||
|date=06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24389059 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2013.12.011 | |||
}} | |||
* {{medline-title | |||
|title=Increased Th17 differentiation in aged mice is significantly associated with high IL-1β level and low IL-2 expression. | |||
|date=01.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24140620 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2013.10.006 | |||
}} | |||
==CD74== | |||
* {{medline-title | |||
|title=Identification of a conserved gene signature associated with an exacerbated inflammatory environment in the hippocampus of aging rats. | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28085212 | |||
|full-text-url=https://sci-hub.do/10.1002/hipo.22703 | |||
}} | |||
* {{medline-title | |||
|title=Intramembrane proteolysis within lysosomes. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27143694 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2016.04.012 | |||
}} | |||
* {{medline-title | |||
|title=Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue. | |||
|date=09.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26253138 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577010 | |||
}} | |||
* {{medline-title | |||
|title=Macrophage migration inhibitory factor confers resistance to senescence through [[CD74]]-dependent AMPK-FOXO3a signaling in mesenchymal stem cells. | |||
|date=22.04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25896286 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453287 | |||
}} | |||
* {{medline-title | |||
|title=Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease. | |||
|date=15.03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24441872 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949087 | |||
}} | |||
* {{medline-title | |||
|title=Effects of minocycline on spatial learning, hippocampal neurogenesis and microglia in aged and adult mice. | |||
|date=01.04.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23274840 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725815 | |||
}} | |||
==CDC42== | |||
* {{medline-title | |||
|title=Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through [[YAP1]]. | |||
|date=05.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31487690 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756888 | |||
}} | |||
* {{medline-title | |||
|title=Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies. | |||
|date=20.10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30341976 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224233 | |||
}} | |||
* {{medline-title | |||
|title=The relationship between reproductive and biochemical ageing at the time of the menopausal transition. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28843511 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.08.028 | |||
}} | |||
* {{medline-title | |||
|title=Senescent cells communicate via intercellular protein transfer. | |||
|date=15.04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25854920 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403256 | |||
}} | |||
* {{medline-title | |||
|title=A crucial role for [[CDC42]] in senescence-associated inflammation and atherosclerosis. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25057989 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109913 | |||
}} | |||
* {{medline-title | |||
|title=[[LOX]]-1 in the maintenance of cytoskeleton and proliferation in senescent cardiac fibroblasts. | |||
|date=07.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23648807 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yjmcc.2013.04.024 | |||
}} | |||
==CTNNB1== | |||
* {{medline-title | |||
|title=Catalog of Lung Cancer Gene Mutations Among Chinese Patients. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850378 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417348 | |||
}} | |||
* {{medline-title | |||
|title=[i][[TP53]][/i] Tumor-suppressor Gene Plays a Key Role in [[IGF1]] Signaling Pathway Related to the Aging of Human Melanocytes. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092438 | |||
|full-text-url=https://sci-hub.do/10.21873/anticanres.13363 | |||
}} | |||
* {{medline-title | |||
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 | |||
}} | |||
* {{medline-title | |||
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277 | |||
|full-text-url=https://sci-hub.do/10.1111/rda.13091 | |||
}} | |||
* {{medline-title | |||
|title=P4 medicine and osteoporosis: a systematic review. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27873024 | |||
|full-text-url=https://sci-hub.do/10.1007/s00508-016-1125-3 | |||
}} | |||
* {{medline-title | |||
|title=Expression profile analysis of new candidate genes for the therapy of primary osteoporosis. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26914116 | |||
}} | |||
==CYP11A1== | |||
* {{medline-title | |||
|title=Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576894 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.12.034 | |||
}} | |||
* {{medline-title | |||
|title=Morphological rearrangement of the cortical region, in aging ovaries. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30589059 | |||
|full-text-url=https://sci-hub.do/10.14670/HH-18-078 | |||
}} | |||
* {{medline-title | |||
|title=Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778464 | |||
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.05.059 | |||
}} | |||
* {{medline-title | |||
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging. | |||
|date=14.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506 | |||
}} | |||
* {{medline-title | |||
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246 | |||
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128 | |||
}} | |||
* {{medline-title | |||
|title=Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs. | |||
|date=01.03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28166986 | |||
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2016.11.007 | |||
}} | |||
==CYP17A1== | |||
* {{medline-title | |||
|title=Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002589 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105764 | |||
}} | |||
* {{medline-title | |||
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246 | |||
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128 | |||
}} | |||
* {{medline-title | |||
|title=Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs. | |||
|date=01.03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28166986 | |||
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2016.11.007 | |||
}} | |||
* {{medline-title | |||
|title=[[CYP17A1]] Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26297028 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886492 | |||
}} | |||
* {{medline-title | |||
|title=Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25275628 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183565 | |||
}} | |||
* {{medline-title | |||
|title=Of mice and men--warning: intact versus castrated adult male mice as xenograft hosts are equivalent to hypogonadal versus abiraterone treated aging human males, respectively. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23775398 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009979 | |||
}} | |||
==DKK1== | |||
* {{medline-title | |||
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448 | |||
}} | |||
* {{medline-title | |||
|title=Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling. | |||
|date=11.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080114 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565990 | |||
}} | |||
* {{medline-title | |||
|title=[Role and alterations of DNA methylation during the aging and cancer]. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647 | |||
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927 | |||
}} | |||
* {{medline-title | |||
|title=Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-[[FOXO1]] pathway. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28507478 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427465 | |||
}} | |||
* {{medline-title | |||
|title=Circulating sclerostin and dickkopf-1 levels in ossification of the posterior longitudinal ligament of the spine. | |||
|date=05.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26040409 | |||
|full-text-url=https://sci-hub.do/10.1007/s00774-015-0671-5 | |||
}} | |||
* {{medline-title | |||
|title=Vaccination with [[DKK1]]-derived peptides promotes bone formation and bone mass in an aged mouse osteoporosis model. | |||
|date=08.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24907907 | |||
|full-text-url=https://sci-hub.do/10.1007/s00223-014-9875-2 | |||
}} | |||
==FGF19== | |||
* {{medline-title | |||
|title=Bile acid receptor agonists in primary biliary cholangitis: Regulation of the cholangiocyte secretome and downstream T cell differentiation. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32123836 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996327 | |||
}} | |||
* {{medline-title | |||
|title=Kotho and aging. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30557478 | |||
}} | |||
* {{medline-title | |||
|title=The Klotho proteins in health and disease. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427 | |||
|full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3 | |||
}} | |||
* {{medline-title | |||
|title=Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765501 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889864 | |||
}} | |||
* {{medline-title | |||
|title=A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion. | |||
|date=08.11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27829151 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120348 | |||
}} | |||
* {{medline-title | |||
|title=A preliminary candidate approach identifies the combination of chemerin, fetuin-A, and fibroblast growth factors 19 and 21 as a potential biomarker panel of successful aging. | |||
|date=06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25911468 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409588 | |||
}} | |||
==GCLM== | |||
* {{medline-title | |||
|title=Silencing Bach1 alters aging-related changes in the expression of Nrf2-regulated genes in primary human bronchial epithelial cells. | |||
|date=15.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31422075 | |||
|full-text-url=https://sci-hub.do/10.1016/j.abb.2019.108074 | |||
}} | |||
* {{medline-title | |||
|title=Ontogeny and aging of Nrf2 pathway genes in livers of rats. | |||
|date=15.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29689272 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2018.04.018 | |||
}} | |||
* {{medline-title | |||
|title=Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377163 | |||
|full-text-url=https://sci-hub.do/10.1111/nyas.13556 | |||
}} | |||
* {{medline-title | |||
|title=Aging-related decline in the induction of Nrf2-regulated antioxidant genes in human bronchial epithelial cells. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28863281 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576992 | |||
}} | |||
* {{medline-title | |||
|title=Nrf2 signaling is impaired in the aging [[RPE]] given an oxidative insult. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24216314 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946784 | |||
}} | |||
* {{medline-title | |||
|title=Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24024152 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757680 | |||
}} | |||
==GEM== | |||
* {{medline-title | |||
|title=The Impact of Geriatric Emergency Management Nurses on the Care of Frail Older Patients in the Emergency Department: a Systematic Review. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32904804 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458600 | |||
}} | |||
* {{medline-title | |||
|title=Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055 | |||
}} | |||
* {{medline-title | |||
|title=Understanding of diagnosis and medications among non-English-speaking older patients. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29377482 | |||
|full-text-url=https://sci-hub.do/10.1111/ajag.12503 | |||
}} | |||
* {{medline-title | |||
|title=Increased gait variability may not imply impaired stride-to-stride control of walking in healthy older adults: Winner: 2013 Gait and Clinical Movement Analysis Society Best Paper Award. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28454071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869351 | |||
}} | |||
* {{medline-title | |||
|title=The development and evaluation of mini-[[GEM]]s - short, focused, online e-learning videos in geriatric medicine. | |||
|date=04-06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27050439 | |||
|full-text-url=https://sci-hub.do/10.1080/02701960.2016.1165217 | |||
}} | |||
* {{medline-title | |||
|title=Neoplastic and nonneoplastic lesions in aging mice of unique and common inbred strains contribution to modeling of human neoplastic diseases. | |||
|date=05.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24019352 | |||
|full-text-url=https://sci-hub.do/10.1177/0300985813501334 | |||
}} | |||
==GLS== | |||
* {{medline-title | |||
|title=Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography. | |||
|date=15.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29784576 | |||
|full-text-url=https://sci-hub.do/10.1016/j.amjcard.2018.03.355 | |||
}} | |||
* {{medline-title | |||
|title=Future Perspectives for Management of Stage A Heart Failure. | |||
|date=01.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731506 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055033 | |||
}} | |||
* {{medline-title | |||
|title=Reference Ranges of Left Ventricular Strain Measures by Two-Dimensional Speckle-Tracking Echocardiography in Children: A Systematic Review and Meta-Analysis. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26747685 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779733 | |||
}} | |||
* {{medline-title | |||
|title=Cardiorespiratory fitness modifies the relationship between myocardial function and cerebral blood flow in older adults. | |||
|date=01.05.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26032886 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029275 | |||
}} | |||
* {{medline-title | |||
|title=Left ventricular strain examination of different aged adults with 3D speckle tracking echocardiography. | |||
|date=03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24028413 | |||
|full-text-url=https://sci-hub.do/10.1111/echo.12367 | |||
}} | |||
* {{medline-title | |||
|title=Left ventricular three-dimensional global systolic strain by real-time three-dimensional speckle-tracking in children: feasibility, reproducibility, maturational changes, and normal ranges. | |||
|date=08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23791113 | |||
|full-text-url=https://sci-hub.do/10.1016/j.echo.2013.05.002 | |||
}} | |||
==GSTP1== | |||
* {{medline-title | |||
|title=DCAF1 regulates Treg senescence via the ROS axis during immunological aging. | |||
|date=02.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32730228 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598062 | |||
}} | |||
* {{medline-title | |||
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684 | |||
}} | |||
* {{medline-title | |||
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632 | |||
}} | |||
* {{medline-title | |||
|title=Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462499 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050201 | |||
}} | |||
* {{medline-title | |||
|title=Epigenetic susceptibility factors for prostate cancer with aging. | |||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23999928 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237278 | |||
}} | |||
* {{medline-title | |||
|title=The age-related change of glutathione antioxidant system in mice liver. | |||
|date=07.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23343351 | |||
|full-text-url=https://sci-hub.do/10.3109/15376516.2013.769655 | |||
}} | |||
==HAL== | |||
* {{medline-title | |||
|title=Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population. | |||
|date=06-09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31066639 | |||
|full-text-url=https://sci-hub.do/10.1080/15360288.2018.1513434 | |||
}} | |||
* {{medline-title | |||
|title=Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31049689 | |||
|full-text-url=https://sci-hub.do/10.1007/s00540-019-02646-0 | |||
}} | |||
* {{medline-title | |||
|title=Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice. | |||
|date=08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28421257 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538925 | |||
}} | |||
* {{medline-title | |||
|title=Differential effects of intermittent versus continuous haloperidol treatment throughout adolescence on haloperidol sensitization and social behavior in adulthood. | |||
|date=03.10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24942467 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134967 | |||
}} | |||
* {{medline-title | |||
|title=HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation. | |||
|date=05.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24366052 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988551 | |||
}} | |||
* {{medline-title | |||
|title=Selective matrix (hyaluronan) interaction with [[CD44]] and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction. | |||
|date=10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23790635 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775883 | |||
}} | |||
==HBP1== | |||
* {{medline-title | |||
|title=Suppression of p38/[[HBP1]] pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence. | |||
|date=03-04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32549582 | |||
|full-text-url=https://sci-hub.do/10.23812/20-63-A-6 | |||
}} | |||
* {{medline-title | |||
|title=Transcription factor [[HBP1]]: A regulator of senescence and apoptosis of preadipocytes. | |||
|date=17.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331641 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.07.048 | |||
}} | |||
* {{medline-title | |||
|title=A positive feedback loop between Pim-1 kinase and [[HBP1]] transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis. | |||
|date=19.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28348080 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437229 | |||
}} | |||
* {{medline-title | |||
|title=Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27206316 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041189 | |||
}} | |||
* {{medline-title | |||
|title=[[HBP1]]-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/[[EZH2]] Pathways and Its Impact on Cell Senescence and Tumorigenesis. | |||
|date=10.06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27129219 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933444 | |||
}} | |||
* {{medline-title | |||
|title=Absence of AMPKα2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26718972 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720555 | |||
}} | |||
==HCN1== | |||
* {{medline-title | |||
|title=Protein expression changes of [[HCN1]] and [[HCN2]] in hippocampal subregions of gerbils during the normal aging process. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32128096 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038419 | |||
}} | |||
* {{medline-title | |||
|title=HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation. | |||
|date=15.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30124776 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376092 | |||
}} | |||
* {{medline-title | |||
|title=Dopaminergic Neurons Exhibit an Age-Dependent Decline in Electrophysiological Parameters in the MitoPark Mouse Model of Parkinson's Disease. | |||
|date=06.04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27053209 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821912 | |||
}} | |||
* {{medline-title | |||
|title=Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes. | |||
|date=11.11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379059 | |||
|full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000455 | |||
}} | |||
* {{medline-title | |||
|title=Age-associated expression of HCN channel isoforms in rat sinoatrial node. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341471 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935443 | |||
}} | |||
* {{medline-title | |||
|title=Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. | |||
|date=27.02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761792 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352274 | |||
}} | |||
==HDAC6== | |||
* {{medline-title | |||
|title=Inhibition of [[HDAC6]] Attenuates Diabetes-Induced Retinal Redox Imbalance and Microangiopathy. | |||
|date=09.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32660051 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402090 | |||
}} | |||
* {{medline-title | |||
|title=Cellular senescence is associated with reorganization of the microtubule cytoskeleton. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30599068 | |||
|full-text-url=https://sci-hub.do/10.1007/s00018-018-2999-1 | |||
}} | |||
* {{medline-title | |||
|title=2,4‑Di‑tert‑butylphenol, a potential [[HDAC6]] inhibitor, induces senescence and mitotic catastrophe in human gastric adenocarcinoma AGS cells. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29427610 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbamcr.2018.02.003 | |||
}} | |||
* {{medline-title | |||
|title=[[HDAC6]] Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of [[PLIN2]] in Drosophila. | |||
|date=09.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28966044 | |||
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2017.09.001 | |||
}} | |||
* {{medline-title | |||
|title=The Deacetylase [[HDAC6]] Mediates Endogenous Neuritic Tau Pathology. | |||
|date=29.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854366 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578720 | |||
}} | |||
* {{medline-title | |||
|title=Declined Expression of Histone Deacetylase 6 Contributes to Periodontal Ligament Stem Cell Aging. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27562218 | |||
|full-text-url=https://sci-hub.do/10.1902/jop.2016.160338 | |||
}} | |||
==HMGA2== | |||
* {{medline-title | |||
|title=4D Genome Rewiring during Oncogene-Induced and Replicative Senescence. | |||
|date=07.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32220303 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208559 | |||
}} | |||
* {{medline-title | |||
|title=The protective effects of [[HMGA2]] in the senescence process of bone marrow-derived mesenchymal stromal cells. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32068957 | |||
|full-text-url=https://sci-hub.do/10.1002/term.3023 | |||
}} | |||
* {{medline-title | |||
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. | |||
|date=05.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005 | |||
}} | |||
* {{medline-title | |||
|title=Molecular differences between stromal cell populations from deciduous and permanent human teeth. | |||
|date=18.04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25927523 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417277 | |||
}} | |||
* {{medline-title | |||
|title=Rb protein is essential to the senescence-associated heterochromatic foci formation induced by [[HMGA2]] in primary WI38 cells. | |||
|date=20.08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23969248 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jgg.2013.05.007 | |||
}} | |||
* {{medline-title | |||
|title=MYCN/[[LIN28B]]/Let-7/[[HMGA2]] pathway implicated by meta-analysis of GWAS in suppression of post-natal proliferation thereby potentially contributing to aging. | |||
|date=07-08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23639551 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2013.04.006 | |||
}} | |||
==HMGB2== | |||
* {{medline-title | |||
|title=Loss of Endogenous [[HMGB2]] Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice. | |||
|date=25.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30487376 | |||
|full-text-url=https://sci-hub.do/10.1253/circj.CJ-18-0925 | |||
}} | |||
* {{medline-title | |||
|title=[[HMGB2]] Loss upon Senescence Entry Disrupts Genomic Organization and Induces [[CTCF]] Clustering across Cell Types. | |||
|date=17.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706538 | |||
|full-text-url=https://sci-hub.do/10.1016/j.molcel.2018.03.030 | |||
}} | |||
* {{medline-title | |||
|title=Correlations between age, functional status, and the senescence-associated proteins [[HMGB2]] and p16 . | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29651745 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964056 | |||
}} | |||
* {{medline-title | |||
|title=Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence. | |||
|date=30.04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487276 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935093 | |||
}} | |||
* {{medline-title | |||
|title=Loss of Endometrial Plasticity in Recurrent Pregnancy Loss. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26418742 | |||
|full-text-url=https://sci-hub.do/10.1002/stem.2222 | |||
}} | |||
* {{medline-title | |||
|title=Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers. | |||
|date=08.10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23969227 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2013.08.007 | |||
}} | |||
==IGF2== | |||
* {{medline-title | |||
|title=Paternal Insulin-like Growth Factor 2 (Igf2) Regulates Stem Cell Activity During Adulthood. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28007480 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233811 | |||
}} | |||
* {{medline-title | |||
|title=Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27294501 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983298 | |||
}} | |||
* {{medline-title | |||
|title=Autocrine Action of [[IGF2]] Regulates Adult β-Cell Mass and Function. | |||
|date=12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26384384 | |||
|full-text-url=https://sci-hub.do/10.2337/db14-1735 | |||
}} | |||
* {{medline-title | |||
|title=Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex. | |||
|date=07.07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26100875 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500222 | |||
}} | |||
* {{medline-title | |||
|title=miR-30e targets [[IGF2]]-regulated osteogenesis in bone marrow-derived mesenchymal stem cells, aortic smooth muscle cells, and ApoE-/- mice. | |||
|date=01.04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25678587 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375408 | |||
}} | |||
* {{medline-title | |||
|title=Epigenetic susceptibility factors for prostate cancer with aging. | |||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23999928 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237278 | |||
}} | |||
==IL4== | |||
* {{medline-title | |||
|title=Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia. | |||
|date=01.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122767 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756472 | |||
}} | |||
* {{medline-title | |||
|title=Aging Affects Bone Marrow Macrophage Polarization: Relevance to Bone Healing. | |||
|date=06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28138512 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270653 | |||
}} | |||
* {{medline-title | |||
|title=[[IL4]]/[[STAT6]] Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain. | |||
|date=18.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27760324 | |||
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2016.09.075 | |||
}} | |||
* {{medline-title | |||
|title=[[IL10]]-driven [[STAT3]] signalling in senescent macrophages promotes pathological eye angiogenesis. | |||
|date=11.08.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26260587 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918330 | |||
}} | |||
* {{medline-title | |||
|title=LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING. | |||
|date=06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26087730 | |||
}} | |||
* {{medline-title | |||
|title=Ageing related periostin expression increase from cardiac fibroblasts promotes cardiomyocytes senescent. | |||
|date=26.09.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25173938 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2014.08.109 | |||
}} | |||
==IRF8== | |||
* {{medline-title | |||
|title=Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33112891 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592753 | |||
}} | |||
* {{medline-title | |||
|title=Hyperglycemia-induced inflamm-aging accelerates gingival senescence via [[NLRC4]] phosphorylation. | |||
|date=06.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31676687 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901307 | |||
}} | |||
* {{medline-title | |||
|title=[[IRF8]] induces senescence of lung cancer cells to exert its tumor suppressive function. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31594449 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927690 | |||
}} | |||
* {{medline-title | |||
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812 | |||
}} | |||
* {{medline-title | |||
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes. | |||
|date=12.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941 | |||
}} | |||
* {{medline-title | |||
|title=Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex. | |||
|date=08.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26002684 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503803 | |||
}} | |||
==JAK1== | |||
* {{medline-title | |||
|title=Implication of [[JAK1]]/[[STAT3]]/[[SOCS3]] Pathway in Aging of Cerebellum of Male Rat: Histological and Molecular study. | |||
|date=01.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32483368 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264275 | |||
}} | |||
* {{medline-title | |||
|title=Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling. | |||
|date=01.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32233952 | |||
|full-text-url=https://sci-hub.do/10.1152/ajpcell.00520.2019 | |||
}} | |||
* {{medline-title | |||
|title=The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Through [[JAK1]]. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396213 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6665952 | |||
}} | |||
* {{medline-title | |||
|title=Influence of age and renal impairment on the steady state pharmacokinetics of filgotinib, a selective [[JAK1]] inhibitor. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088677 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256002 | |||
}} | |||
* {{medline-title | |||
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012 | |||
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006 | |||
}} | |||
* {{medline-title | |||
|title=Interferon-γ induces senescence in normal human melanocytes. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24681574 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969336 | |||
}} | |||
==KIT== | |||
* {{medline-title | |||
|title=Prediction of ovarian aging using ovarian expression of [[BMP15]], [[GDF9]], and C-[[KIT]]. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223330 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221484 | |||
}} | |||
* {{medline-title | |||
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.26231 | |||
}} | |||
* {{medline-title | |||
|title=Comparison of Changes in the Interstitial Cells of Cajal and Neuronal Nitric Oxide Synthase-positive Neuronal Cells With Aging Between the Ascending and Descending Colon of F344 Rats. | |||
|date=30.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28774159 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628993 | |||
}} | |||
* {{medline-title | |||
|title=Leukocyte telomere length in mastocytosis: correlations with depression and perceived stress. | |||
|date=01.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23917070 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2013.07.009 | |||
}} | |||
* {{medline-title | |||
|title=Changes of number of cells expressing proliferation and progenitor cell markers with age in rabbit intervertebral discs. | |||
|date=05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23449074 | |||
|full-text-url=https://sci-hub.do/10.1093/abbs/gmt019 | |||
}} | |||
* {{medline-title | |||
|title=Systemic mastocytosis in the elderly. | |||
|date=05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23436294 | |||
|full-text-url=https://sci-hub.do/10.1002/ajh.23426 | |||
}} | |||
==LAMP2== | |||
* {{medline-title | |||
|title=An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into [[RPE]] Stress Associated with Retinopathy. | |||
|date=11.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32932802 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555953 | |||
}} | |||
* {{medline-title | |||
|title=Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells. | |||
|date=01.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32244623 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235898 | |||
}} | |||
* {{medline-title | |||
|title=Genetic [[LAMP2]] deficiency accelerates the age-associated formation of basal laminar deposits in the retina. | |||
|date=19.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31699817 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876195 | |||
}} | |||
* {{medline-title | |||
|title=[[SQSTM1]]/p62 and [[PPARGC1A]]/PGC-1alpha at the interface of autophagy and vascular senescence. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441382 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469683 | |||
}} | |||
* {{medline-title | |||
|title=A pH probe inhibits senescence in mesenchymal stem cells. | |||
|date=07.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523 | |||
}} | |||
* {{medline-title | |||
|title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022 | |||
}} | |||
==MAPK1== | |||
* {{medline-title | |||
|title=Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850814 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413062 | |||
}} | |||
* {{medline-title | |||
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 | |||
}} | |||
* {{medline-title | |||
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201 | |||
}} | |||
* {{medline-title | |||
|title=iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation. | |||
|date=01.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708522 | |||
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.06.014 | |||
}} | |||
* {{medline-title | |||
|title=Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging. | |||
|date=01.07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28515230 | |||
|full-text-url=https://sci-hub.do/10.1242/jcs.197327 | |||
}} | |||
* {{medline-title | |||
|title=Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25592202 | |||
|full-text-url=https://sci-hub.do/10.1159/000368305 | |||
}} | |||
==MCU== | |||
* {{medline-title | |||
|title=A rare case of Epstein-Barr virus-positive mucocutaneous ulcer that developed into an intestinal obstruction: a case report. | |||
|date=13.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31931725 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958744 | |||
}} | |||
* {{medline-title | |||
|title=Inhibition of Mitochondrial Calcium Overload by [[SIRT3]] Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31712319 | |||
|full-text-url=https://sci-hub.do/10.2337/db19-0526 | |||
}} | |||
* {{medline-title | |||
|title=Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055 | |||
}} | |||
* {{medline-title | |||
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923 | |||
}} | |||
* {{medline-title | |||
|title=Physical exercise in aging human skeletal muscle increases mitochondrial calcium uniporter expression levels and affects mitochondria dynamics. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28039397 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210373 | |||
}} | |||
* {{medline-title | |||
|title=Evolution of increased adult longevity in Drosophila melanogaster populations selected for adaptation to larval crowding. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26575793 | |||
|full-text-url=https://sci-hub.do/10.1111/jeb.12795 | |||
}} | |||
==MEF2C== | |||
* {{medline-title | |||
|title=Decline in cellular function of aged mouse c-kit cardiac progenitor cells. | |||
|date=01.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28737214 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621489 | |||
}} | |||
* {{medline-title | |||
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. | |||
|date=11.04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828 | |||
}} | |||
* {{medline-title | |||
|title=Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. | |||
|date=01.12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27616567 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837042 | |||
}} | |||
* {{medline-title | |||
|title=Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27612437 | |||
|full-text-url=https://sci-hub.do/10.1002/stem.2495 | |||
}} | |||
* {{medline-title | |||
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889 | |||
}} | |||
* {{medline-title | |||
|title=Postnatal expression patterns and polymorphism analysis of the bovine myocyte enhancer factor 2C (Mef2C) gene. | |||
|date=12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25108515 | |||
|full-text-url=https://sci-hub.do/10.1016/j.meatsci.2014.06.015 | |||
}} | |||
==MME== | |||
* {{medline-title | |||
|title=Geriatric Opioid Harm Reduction: Interprofessional Student Learning Outcomes. | |||
|date=01-12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32284953 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139179 | |||
}} | |||
* {{medline-title | |||
|title=Effectiveness of local anesthetic injection in geriatric patients following operative management of proximal and diaphyseal femur fracture. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31564373 | |||
|full-text-url=https://sci-hub.do/10.1016/j.injury.2019.09.013 | |||
}} | |||
* {{medline-title | |||
|title=Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic [[PIK3CA]] accompanied with pro-tumorigenic secretome. | |||
|date=01.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30671946 | |||
|full-text-url=https://sci-hub.do/10.1002/ijc.32153 | |||
}} | |||
* {{medline-title | |||
|title=Medial meniscus extrusion increases with age and BMI and is depending on different loading conditions. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29511818 | |||
|full-text-url=https://sci-hub.do/10.1007/s00167-018-4885-7 | |||
}} | |||
* {{medline-title | |||
|title=Rare Variants in [[MME]], Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies. | |||
|date=01.09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27588448 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011077 | |||
}} | |||
* {{medline-title | |||
|title=Genetic analysis of mesangial matrix expansion in aging mice and identification of Far2 as a candidate gene. | |||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24009241 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839541 | |||
}} | |||
==MVD== | |||
* {{medline-title | |||
|title=Young and elderly oral squamous cell carcinoma patients present similar angiogenic profile and predominance of M2 macrophages: Comparative immunohistochemical study. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31497915 | |||
|full-text-url=https://sci-hub.do/10.1002/hed.25954 | |||
}} | |||
* {{medline-title | |||
|title=Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297390 | |||
|full-text-url=https://sci-hub.do/10.1136/jim-2018-000804 | |||
}} | |||
* {{medline-title | |||
|title=Assessing Microvascular Function in Humans from a Chronic Disease Perspective. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904002 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698072 | |||
}} | |||
* {{medline-title | |||
|title=Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women. | |||
|date=08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28316011 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514208 | |||
}} | |||
* {{medline-title | |||
|title=Diffusion-weighted multiparametric MRI for monitoring longitudinal changes of parameters in rabbit VX2 liver tumors. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26878263 | |||
|full-text-url=https://sci-hub.do/10.1002/jmri.25179 | |||
}} | |||
* {{medline-title | |||
|title=[Expression of vascular endothelial growth factor and microvessel density in different brain regions in aged rats]. | |||
|date=07.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25080903 | |||
|full-text-url=https://sci-hub.do/10.11817/j.issn.1672-7347.2014.07.005 | |||
}} | |||
==NDUFB8== | |||
* {{medline-title | |||
|title=Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature. | |||
|date=15.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32326435 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227017 | |||
}} | |||
* {{medline-title | |||
|title=Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. | |||
|date=12.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32059608 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074517 | |||
}} | |||
* {{medline-title | |||
|title=Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. | |||
|date=23.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29882895 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032417 | |||
}} | |||
* {{medline-title | |||
|title=Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29802507 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060193 | |||
}} | |||
* {{medline-title | |||
|title=Resveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway. | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26873850 | |||
|full-text-url=https://sci-hub.do/10.1007/s12035-016-9770-0 | |||
}} | |||
* {{medline-title | |||
|title=Reduced levels of mitochondrial complex I subunit [[NDUFB8]] and linked complex I III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24217272 | |||
|full-text-url=https://sci-hub.do/10.3233/JAD-131499 | |||
}} | |||
==NF1== | |||
* {{medline-title | |||
|title=Conditional reprograming culture conditions facilitate growth of lower grade glioma models. | |||
|date=01.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33258947 | |||
|full-text-url=https://sci-hub.do/10.1093/neuonc/noaa263 | |||
}} | |||
* {{medline-title | |||
|title=Circular RNA [[NF1]]-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice. | |||
|date=20.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31860870 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949063 | |||
}} | |||
* {{medline-title | |||
|title=[[NF1]] loss induces senescence during human melanocyte differentiation in an iPSC-based model. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25824590 | |||
|full-text-url=https://sci-hub.do/10.1111/pcmr.12369 | |||
}} | |||
* {{medline-title | |||
|title=TGF-β/[[NF1]]/Smad4-mediated suppression of ANT2 contributes to oxidative stress in cellular senescence. | |||
|date=12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25220407 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2014.08.029 | |||
}} | |||
* {{medline-title | |||
|title=Neuropsychological impairments in elderly Neurofibromatosis type 1 patients. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24556498 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ejmg.2014.02.004 | |||
}} | |||
* {{medline-title | |||
|title=Long-term prognosis of patients with pediatric pheochromocytoma. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24169644 | |||
|full-text-url=https://sci-hub.do/10.1530/ERC-13-0415 | |||
}} | |||
==NOS3== | |||
* {{medline-title | |||
|title=Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation. | |||
|date=22.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32455928 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290800 | |||
}} | |||
* {{medline-title | |||
|title=Hypertension and longevity: role of genetic polymorphisms in renin-angiotensin-aldosterone system and endothelial nitric oxide synthase. | |||
|date=05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30460536 | |||
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3470-1 | |||
}} | |||
* {{medline-title | |||
|title=[[NOS3]] Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels. | |||
|date=11.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891729 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041791 | |||
}} | |||
* {{medline-title | |||
|title=Vascular senescence and ageing: a role for the MEOX proteins in promoting endothelial dysfunction. | |||
|date=10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28727928 | |||
|full-text-url=https://sci-hub.do/10.1139/cjpp-2017-0149 | |||
}} | |||
* {{medline-title | |||
|title=Fetal programming of blood pressure in a transgenic mouse model of altered intrauterine environment. | |||
|date=01.12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27506899 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134377 | |||
}} | |||
* {{medline-title | |||
|title=Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans. | |||
|date=04.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23572278 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-013-9421-z | |||
}} | |||
==NPR1== | |||
* {{medline-title | |||
|title=The [[NPR1]]-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana. | |||
|date=03.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33270345 | |||
|full-text-url=https://sci-hub.do/10.1111/jipb.13044 | |||
}} | |||
* {{medline-title | |||
|title=Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis. | |||
|date=07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32540002 | |||
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2020.110472 | |||
}} | |||
* {{medline-title | |||
|title=Some things get better with age: differences in salicylic acid accumulation and defense signaling in young and mature Arabidopsis. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25620972 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288333 | |||
}} | |||
* {{medline-title | |||
|title=Mitogen-activated protein kinase 6 regulates [[NPR1]] gene expression and activation during leaf senescence induced by salicylic acid. | |||
|date=12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25210078 | |||
|full-text-url=https://sci-hub.do/10.1093/jxb/eru369 | |||
}} | |||
* {{medline-title | |||
|title=Autophagy deficiency leads to accumulation of ubiquitinated proteins, ER stress, and cell death in Arabidopsis. | |||
|date=09.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25046116 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206536 | |||
}} | |||
* {{medline-title | |||
|title=A dissection of the effects of ethylene, H2O2 and high irradiance on antioxidants and several genes associated with stress and senescence in tobacco leaves. | |||
|date=15.02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24119414 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jplph.2013.08.007 | |||
}} | |||
==NRK== | |||
* {{medline-title | |||
|title=[Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/[[ULK1]] signaling activation]. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989992 | |||
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20181205.001 | |||
}} | |||
* {{medline-title | |||
|title=Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-[[ULK1]] signaling-mediated autophagy. | |||
|date=24.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585174 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326678 | |||
}} | |||
* {{medline-title | |||
|title=Fascin2 regulates cisplatin-induced apoptosis in [[NRK]]-52E cells. | |||
|date=15.01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27989596 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074922 | |||
}} | |||
* {{medline-title | |||
|title=2,3,5,4'-Tetrahydroxystilbene-2-O-[i]β[/i]-D-glucoside Promotes Expression of the Longevity Gene Klotho. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27885332 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112329 | |||
}} | |||
* {{medline-title | |||
|title=A role for the age-dependent loss of α(E)-catenin in regulation of N-cadherin expression and cell migration. | |||
|date=01.06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24920123 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208646 | |||
}} | |||
* {{medline-title | |||
|title=Overexpression of MMP-7 Increases Collagen 1A2 in the Aging Kidney. | |||
|date=10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24273653 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834982 | |||
}} | |||
==PAK1== | |||
* {{medline-title | |||
|title=1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating [[PAK1]] at nM levels. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760342 | |||
|full-text-url=https://sci-hub.do/10.5582/ddt.2018.01018 | |||
}} | |||
* {{medline-title | |||
|title=From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic [[PAK1]]-blockers/longevity-promoters for cancer therapy. | |||
|date=15.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814374 | |||
|full-text-url=https://sci-hub.do/10.1016/j.ejmech.2017.07.043 | |||
}} | |||
* {{medline-title | |||
|title=Effect of Okinawa Propolis on [[PAK1]] Activity, Caenorhabditis elegans Longevity, Melanogenesis, and Growth of Cancer Cells. | |||
|date=13.07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27337169 | |||
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.6b01785 | |||
}} | |||
* {{medline-title | |||
|title=Several herbal compounds in Okinawa plants directly inhibit the oncogenic/aging kinase [[PAK1]]. | |||
|date=12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25639302 | |||
|full-text-url=https://sci-hub.do/10.5582/ddt.2014.01045 | |||
}} | |||
* {{medline-title | |||
|title=Herbal therapeutics that block the oncogenic kinase [[PAK1]]: a practical approach towards [[PAK1]]-dependent diseases and longevity. | |||
|date=05.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23943274 | |||
|full-text-url=https://sci-hub.do/10.1002/ptr.5054 | |||
}} | |||
* {{medline-title | |||
|title=[[PAK1]]-deficiency/down-regulation reduces brood size, activates HSP16.2 gene and extends lifespan in Caenorhabditis elegans. | |||
|date=02.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23524941 | |||
|full-text-url=https://sci-hub.do/10.5582/ddt.2013.v7.1.29 | |||
}} | |||
==PGP== | |||
* {{medline-title | |||
|title=Age-associated changes of the intrinsic nervous system in relation with interstitial cells in the pre-weaning goat rumen. | |||
|date=14.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31305258 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660047 | |||
}} | |||
* {{medline-title | |||
|title=Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182640 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705109 | |||
}} | |||
* {{medline-title | |||
|title=Change in the Interstitial Cells of Cajal and nNOS Positive Neuronal Cells with Aging in the Stomach of F344 Rats. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28045993 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207530 | |||
}} | |||
* {{medline-title | |||
|title=The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via [[CXCR1]]-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27769935 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2016.10.011 | |||
}} | |||
* {{medline-title | |||
|title=[CHANGES IN [[TH]]E PANCREATIC ISLETS AND NERVOUS ELEMENTS IN RATS DURING AGING (AN IMMUNOHISTOCHEMICAL STUDY)]. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27141588 | |||
}} | |||
* {{medline-title | |||
|title=Associations between xerostomia, histopathological alterations, and autonomic innervation of labial salivary glands in men in late midlife. | |||
|date=09.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24905142 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2014.06.004 | |||
}} | |||
==POR== | |||
* {{medline-title | |||
|title=The Ventricular System Enlarges Abnormally in the Seventies, Earlier in Men, and First in the Frontal Horn: A Study Based on More Than 3,000 Scans. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31749695 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848156 | |||
}} | |||
* {{medline-title | |||
|title=Clinical findings associated with development of postoperative reflux and short-term survival after small intestinal surgery in geriatric and mature nongeriatric horses. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002397 | |||
|full-text-url=https://sci-hub.do/10.1111/vsu.13217 | |||
}} | |||
* {{medline-title | |||
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. | |||
|date=12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906 | |||
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442 | |||
}} | |||
* {{medline-title | |||
|title=Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis. | |||
|date=01.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28412544 | |||
|full-text-url=https://sci-hub.do/10.1016/j.molp.2017.03.011 | |||
}} | |||
* {{medline-title | |||
|title=Endometriosis has no negative impact on outcomes of in vitro fertilisation in women with poor ovarian response. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27627604 | |||
|full-text-url=https://sci-hub.do/10.1111/1471-0528.14018 | |||
}} | |||
* {{medline-title | |||
|title=Short-term complications after colic surgery in geriatric versus mature non-geriatric horses. | |||
|date=02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25289944 | |||
|full-text-url=https://sci-hub.do/10.1111/j.1532-950X.2014.12281.x | |||
}} | |||
==POT1== | |||
* {{medline-title | |||
|title=Decreased expression of [[TERT]] and telomeric proteins as human ovaries age may cause telomere shortening. | |||
|date=27.08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856217 | |||
|full-text-url=https://sci-hub.do/10.1007/s10815-020-01932-1 | |||
}} | |||
* {{medline-title | |||
|title=MiR-185 targets [[POT1]] to induce telomere dysfunction and cellular senescence. | |||
|date=18.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32687062 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425516 | |||
}} | |||
* {{medline-title | |||
|title=Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. | |||
|date=05.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109421 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058826 | |||
}} | |||
* {{medline-title | |||
|title=Seryl tRNA synthetase cooperates with [[POT1]] to regulate telomere length and cellular senescence. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31815007 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882858 | |||
}} | |||
* {{medline-title | |||
|title=A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region. | |||
|date=03.11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26462146 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742130 | |||
}} | |||
* {{medline-title | |||
|title=Caenorhabditis elegans POT-1 and POT-2 repress telomere maintenance pathways. | |||
|date=02.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23390606 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564990 | |||
}} | |||
==PRC1== | |||
* {{medline-title | |||
|title=Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. | |||
|date=24.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32979540 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115659 | |||
}} | |||
* {{medline-title | |||
|title=Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein [[BMI1]] in breast cancer cells. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528145 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986597 | |||
}} | |||
* {{medline-title | |||
|title=Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177687 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9737-1 | |||
}} | |||
* {{medline-title | |||
|title=The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27442247 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956247 | |||
}} | |||
* {{medline-title | |||
|title=[[CBX7]] and miR-9 are part of an autoregulatory loop controlling p16(INK) (4a). | |||
|date=12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26416703 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693451 | |||
}} | |||
* {{medline-title | |||
|title=Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7. | |||
|date=20.12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24194518 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868753 | |||
}} | |||
==PROC== | |||
* {{medline-title | |||
|title=Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation. | |||
|date=15.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633180 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157190 | |||
}} | |||
* {{medline-title | |||
|title=Effects of feeding frequency of an elevated plane of milk replacer and calf age on behavior, and glucose and insulin kinetics in male Holstein calves. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30419975 | |||
|full-text-url=https://sci-hub.do/10.1017/S175173111800294X | |||
}} | |||
* {{medline-title | |||
|title=Age-related effects on markers of inflammation and cartilage metabolism in response to an intra-articular lipopolysaccharide challenge in horses. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28380609 | |||
|full-text-url=https://sci-hub.do/10.2527/jas.2016.1078 | |||
}} | |||
* {{medline-title | |||
|title=Normative data for rotational chair stratified by age. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26227880 | |||
|full-text-url=https://sci-hub.do/10.1002/lary.25497 | |||
}} | |||
* {{medline-title | |||
|title=Day-to-Day Impact of Vaginal Aging questionnaire: a multidimensional measure of the impact of vaginal symptoms on functioning and well-being in postmenopausal women. | |||
|date=02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24983271 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280352 | |||
}} | |||
* {{medline-title | |||
|title=Growth and feed conversion efficiency of Dorper and Rambouillet lambs. | |||
|date=10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23893989 | |||
|full-text-url=https://sci-hub.do/10.2527/jas.2012-6226 | |||
}} | |||
==PTGS2== | |||
* {{medline-title | |||
|title=Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31811565 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062590 | |||
}} | |||
* {{medline-title | |||
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. | |||
|date=21.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237 | |||
}} | |||
* {{medline-title | |||
|title=Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging. | |||
|date=28.12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28031022 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198498 | |||
}} | |||
* {{medline-title | |||
|title=Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25329999 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203852 | |||
}} | |||
* {{medline-title | |||
|title=Coordination of gene expression of arachidonic and docosahexaenoic acid cascade enzymes during human brain development and aging. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24963629 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070994 | |||
}} | |||
* {{medline-title | |||
|title=Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer's disease animal model. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24194717 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810591 | |||
}} | |||
==PTX3== | |||
* {{medline-title | |||
|title=Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. | |||
|date=27.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012711 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070734 | |||
}} | |||
* {{medline-title | |||
|title=Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study. | |||
|date=13.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31808814 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357589 | |||
}} | |||
* {{medline-title | |||
|title=Changes in Proteomic Profiles are Related to Changes in BMI and Fat Distribution During 10 Years of Aging. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31804015 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986305 | |||
}} | |||
* {{medline-title | |||
|title=Inflammatory Long Pentraxin 3 is Associated with Leukocyte Telomere Length in Night-Shift Workers. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28536575 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422482 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent cellular reactions of the human immune system of humanized NOD scid gamma mice on LPS stimulus. | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28162006 | |||
|full-text-url=https://sci-hub.do/10.1177/1753425917690814 | |||
}} | |||
* {{medline-title | |||
|title=Elevated pentraxin 3 level at the early stage of exercise training is associated with reduction of arterial stiffness in middle-aged and older adults. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26467819 | |||
|full-text-url=https://sci-hub.do/10.1038/jhh.2015.105 | |||
}} | |||
==RB1== | |||
* {{medline-title | |||
|title=Expression of p16 in nodular fasciitis: an implication for self-limited and inflammatory nature of the lesion. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31933915 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945175 | |||
}} | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 | |||
}} | |||
* {{medline-title | |||
|title=Mesenchymal stromal cells having inactivated [[RB1]] survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27124644 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323029 | |||
}} | |||
* {{medline-title | |||
|title=Suppression of [[RAD21]] Induces Senescence of MDA-[[MB]]-231 Human Breast Cancer Cells Through [[RB1]] Pathway Activation Via c-Myc Downregulation. | |||
|date=06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26529363 | |||
|full-text-url=https://sci-hub.do/10.1002/jcb.25426 | |||
}} | |||
* {{medline-title | |||
|title=[[RB1]]-mediated cell-autonomous and host-dependent oncosuppressor mechanisms in radiation-induced osteosarcoma. | |||
|date=01.01.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24800165 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006854 | |||
}} | |||
* {{medline-title | |||
|title=Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging. | |||
|date=08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23819996 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748192 | |||
}} | |||
==RIG== | |||
* {{medline-title | |||
|title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393 | |||
}} | |||
* {{medline-title | |||
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes. | |||
|date=12.12.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941 | |||
}} | |||
* {{medline-title | |||
|title=Random Item Generation Is Affected by Age. | |||
|date=01.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27681687 | |||
|full-text-url=https://sci-hub.do/10.1044/2016_JSLHR-L-15-0077 | |||
}} | |||
* {{medline-title | |||
|title=Aging-related renal injury and inflammation are associated with downregulation of Klotho and induction of [[RIG]]-I/NF-κB signaling pathway in senescence-accelerated mice. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25986237 | |||
|full-text-url=https://sci-hub.do/10.1007/s40520-015-0371-y | |||
}} | |||
* {{medline-title | |||
|title=Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors. | |||
|date=06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25728020 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406671 | |||
}} | |||
* {{medline-title | |||
|title=Attenuation of respiratory syncytial virus-induced and [[RIG]]-I-dependent type I IFN responses in human neonates and very young children. | |||
|date=01.02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24391215 | |||
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1302007 | |||
}} | |||
==RIPK1== | |||
* {{medline-title | |||
|title=Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. | |||
|date=18.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33206046 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673785 | |||
}} | |||
* {{medline-title | |||
|title=Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31981738 | |||
|full-text-url=https://sci-hub.do/10.1016/j.joca.2020.01.004 | |||
}} | |||
* {{medline-title | |||
|title=RIP kinases as modulators of inflammation and immunity. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615 | |||
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x | |||
}} | |||
* {{medline-title | |||
|title=[[TBK1]] Suppresses [[RIPK1]]-Driven Apoptosis and Inflammation during Development and in Aging. | |||
|date=06.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30146158 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128749 | |||
}} | |||
* {{medline-title | |||
|title=Necroptosis increases with age and is reduced by dietary restriction. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696779 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052392 | |||
}} | |||
* {{medline-title | |||
|title=[[RIPK1]]-[[RIPK3]]-[[MLKL]]-dependent necrosis promotes the aging of mouse male reproductive system. | |||
|date=15.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807105 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557593 | |||
}} | |||
==S100A8== | |||
* {{medline-title | |||
|title=Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice. | |||
|date=15.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678243 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894395 | |||
}} | |||
* {{medline-title | |||
|title=[[S100A8]], which increases with age, induces cellular senescence-like changes in bovine oviduct epithelial cells. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237976 | |||
|full-text-url=https://sci-hub.do/10.1111/aji.13163 | |||
}} | |||
* {{medline-title | |||
|title=Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model. | |||
|date=06.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991479 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078409 | |||
}} | |||
* {{medline-title | |||
|title=Lung cellular senescence is independent of aging in a mouse model of COPD/emphysema. | |||
|date=13.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29899396 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998122 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent changes in inflammation and extracellular matrix in bovine oviduct epithelial cells during the post-ovulatory phase. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27580129 | |||
|full-text-url=https://sci-hub.do/10.1002/mrd.22693 | |||
}} | |||
* {{medline-title | |||
|title=A transcriptional roadmap to the senescence and differentiation of human oral keratinocytes. | |||
|date=01.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24398559 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/glt212 | |||
}} | |||
==SERPINE1== | |||
* {{medline-title | |||
|title=Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33041998 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525127 | |||
}} | |||
* {{medline-title | |||
|title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272174 | |||
|full-text-url=https://sci-hub.do/10.1016/j.antiviral.2020.104784 | |||
}} | |||
* {{medline-title | |||
|title=Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes. | |||
|date=15.01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32056555 | |||
|full-text-url=https://sci-hub.do/10.1016/j.placenta.2019.12.012 | |||
}} | |||
* {{medline-title | |||
|title=Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31811565 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062590 | |||
}} | |||
* {{medline-title | |||
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature. | |||
|date=18.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778 | |||
}} | |||
* {{medline-title | |||
|title=A null mutation in [i][[SERPINE1]][/i] protects against biological aging in humans. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29152572 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687852 | |||
}} | |||
==SHH== | |||
* {{medline-title | |||
|title=Recent advances in [[SHH]] medulloblastoma progression: tumor suppressor mechanisms and the tumor microenvironment. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31700613 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820827 | |||
}} | |||
* {{medline-title | |||
|title=An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through [[SERPINB2]]. | |||
|date=03.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080015 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612665 | |||
}} | |||
* {{medline-title | |||
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483 | |||
}} | |||
* {{medline-title | |||
|title=Evasion of cell senescence in [[SHH]] medulloblastoma. | |||
|date=17.08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27229128 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993422 | |||
}} | |||
* {{medline-title | |||
|title=Expression and Role of Sonic Hedgehog in the Process of Fracture Healing with Aging. | |||
|date=03-04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912819 | |||
}} | |||
* {{medline-title | |||
|title=The Subjective Health Horizon Questionnaire ([[SHH]]-Q): Assessing Future Time Perspectives for Facets of an Active Lifestyle. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26820307 | |||
|full-text-url=https://sci-hub.do/10.1159/000441493 | |||
}} | |||
==SNAP25== | |||
* {{medline-title | |||
|title=The Biological Foundations of Sarcopenia: Established and Promising Markers. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31457015 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700259 | |||
}} | |||
* {{medline-title | |||
|title=Contribution of adenosine and ATP to the carotid body chemosensory activity in ageing. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31426127 | |||
|full-text-url=https://sci-hub.do/10.1113/JP274179 | |||
}} | |||
* {{medline-title | |||
|title=Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29496544 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483375 | |||
}} | |||
* {{medline-title | |||
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327 | |||
}} | |||
* {{medline-title | |||
|title=Global hypoxia induced impairment in learning and spatial memory is associated with precocious hippocampal aging. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27246251 | |||
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2016.05.011 | |||
}} | |||
* {{medline-title | |||
|title=[[NOS1]] and [[SNAP25]] polymorphisms are associated with Attention-Deficit/Hyperactivity Disorder symptoms in adults but not in children. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26821215 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2016.01.010 | |||
}} | |||
==SOST== | |||
* {{medline-title | |||
|title=Remodeling process in bone of aged rats in response to resistance training. | |||
|date=01.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593709 | |||
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118008 | |||
}} | |||
* {{medline-title | |||
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448 | |||
}} | |||
* {{medline-title | |||
|title=Bone adaptation in response to treadmill exercise in young and adult mice. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29379848 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787623 | |||
}} | |||
* {{medline-title | |||
|title=WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling. | |||
|date=29.05.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25864198 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447973 | |||
}} | |||
* {{medline-title | |||
|title=Relative influence of heritability, environment and genetics on serum sclerostin. | |||
|date=03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24136102 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948173 | |||
}} | |||
* {{medline-title | |||
|title=Novel sandwich ELISAs for rat [[DMP1]]: age-related decrease of circulatory [[DMP1]] levels in male rats. | |||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24076023 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bone.2013.09.013 | |||
}} | |||
==SPR== | |||
* {{medline-title | |||
|title=Regulation of lifespan by neural excitation and [[REST]]. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31619788 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893853 | |||
}} | |||
* {{medline-title | |||
|title=How many geriatricians should, at minimum, be staffing health regions in Australia? | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171127 | |||
|full-text-url=https://sci-hub.do/10.1111/ajag.12467 | |||
}} | |||
* {{medline-title | |||
|title=Mutation of C. elegans demethylase spr-5 extends transgenerational longevity. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26691751 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746603 | |||
}} | |||
* {{medline-title | |||
|title=[[REST]] and stress resistance in ageing and Alzheimer's disease. | |||
|date=27.03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24670762 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110979 | |||
}} | |||
* {{medline-title | |||
|title=H3K4 demethylase activities repress proliferative and postmitotic aging. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24134677 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020274 | |||
}} | |||
* {{medline-title | |||
|title=Increase in tetrahydrobiopterin concentration with aging in the cerebral cortex of the senescence-accelerated mouse prone 10 strain caused by abnormal regulation of tetrahydrobiopterin biosynthesis. | |||
|date=10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23933678 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-013-9452-5 | |||
}} | |||
==TBP== | |||
* {{medline-title | |||
|title=Identification of reference genes for RT-qPCR data normalisation in aging studies. | |||
|date=27.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562345 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764958 | |||
}} | |||
* {{medline-title | |||
|title=Trinucleotide repeat expansion of TATA-binding protein gene associated with Parkinson's disease: A Thai multicenter study. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27172828 | |||
|full-text-url=https://sci-hub.do/10.1016/j.parkreldis.2016.05.008 | |||
}} | |||
* {{medline-title | |||
|title=[[CALHM1]] Deletion in Mice Affects Glossopharyngeal Taste Responses, Food Intake, Body Weight, and Life Span. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25855639 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542651 | |||
}} | |||
* {{medline-title | |||
|title=Deactivation of [[TBP]] contributes to SCA17 pathogenesis. | |||
|date=20.12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25104854 | |||
|full-text-url=https://sci-hub.do/10.1093/hmg/ddu410 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent decrease in chaperone activity impairs [[MANF]] expression, leading to Purkinje cell degeneration in inducible SCA17 mice. | |||
|date=22.01.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24462098 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863472 | |||
}} | |||
* {{medline-title | |||
|title=[Age estimation using content of sjTREC in human peripheral blood]. | |||
|date=08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24350539 | |||
}} | |||
==TCF7L2== | |||
* {{medline-title | |||
|title=A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32015540 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065955 | |||
}} | |||
* {{medline-title | |||
|title=The dynamic methylome of islets in health and disease. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500828 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768570 | |||
}} | |||
* {{medline-title | |||
|title=Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle. | |||
|date=01.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30824849 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397284 | |||
}} | |||
* {{medline-title | |||
|title=[[TCF7L1]] promotes skin tumorigenesis independently of β-catenin through induction of [[LCN2]]. | |||
|date=03.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28467300 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438253 | |||
}} | |||
* {{medline-title | |||
|title=[Frequency of some diseases and conditions in geriatric patients with coronary heart disease and various genotypes of transcription factor 7-like 2 protein]. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25946847 | |||
}} | |||
* {{medline-title | |||
|title=Aging and cardiovascular diseases: the role of gene-diet interactions. | |||
|date=11.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25159268 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2014.08.002 | |||
}} | |||
==TET1== | |||
* {{medline-title | |||
|title=DNA methylation instability by [[BRAF]]-mediated TET silencing and lifestyle-exposure divides colon cancer pathways. | |||
|date=16.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31842975 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916434 | |||
}} | |||
* {{medline-title | |||
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493 | |||
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y | |||
}} | |||
* {{medline-title | |||
|title=Epigenetic Co-Deregulation of [[EZH2]]/[[TET1]] is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30809307 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376470 | |||
}} | |||
* {{medline-title | |||
|title=DNA Hydroxymethylation Levels Are Altered in Blood Cells From Down Syndrome Persons Enrolled in the MARK-AGE Project. | |||
|date=09.05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29069286 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946825 | |||
}} | |||
* {{medline-title | |||
|title=Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts. | |||
|date=07.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24746615 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410980 | |||
}} | |||
* {{medline-title | |||
|title=On your (methyl) mark, get [[TET1]], go! | |||
|date=01.08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23910076 | |||
|full-text-url=https://sci-hub.do/10.1016/j.stem.2013.07.011 | |||
}} | |||
==TLR3== | |||
* {{medline-title | |||
|title=Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. | |||
|date=01.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32969782 | |||
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00615.2020 | |||
}} | |||
* {{medline-title | |||
|title=The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Through [[JAK1]]. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396213 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6665952 | |||
}} | |||
* {{medline-title | |||
|title=Repetitive [[TLR3]] activation in the lung induces skeletal muscle adaptations and cachexia. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452288 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911410 | |||
}} | |||
* {{medline-title | |||
|title=Age-related changes and distribution of T cell markers (CD3 and [[CD4]]) and toll-like receptors(TLR2, [[TLR3]],[[TLR4]] and [[TLR7]]) in the duck lymphoid organs. | |||
|date=07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356195 | |||
|full-text-url=https://sci-hub.do/10.1016/j.imbio.2017.01.004 | |||
}} | |||
* {{medline-title | |||
|title=Effect of age on the pathogenesis of DHV-1 in Pekin ducks and on the innate immune responses of ducks to infection. | |||
|date=05.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24162826 | |||
|full-text-url=https://sci-hub.do/10.1007/s00705-013-1900-7 | |||
}} | |||
* {{medline-title | |||
|title=[What's new in dermatological research?]. | |||
|date=12.2012 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23522705 | |||
|full-text-url=https://sci-hub.do/10.1016/S0151-9638(12)70133-3 | |||
}} | |||
==TPO== | |||
* {{medline-title | |||
|title=Megakaryocytes promote osteoclastogenesis in aging. | |||
|date=07.07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634116 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425434 | |||
}} | |||
* {{medline-title | |||
|title=To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex-independent) NOD.H2 mice. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566234 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422661 | |||
}} | |||
* {{medline-title | |||
|title=Kras is Required for Adult Hematopoiesis. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26972179 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358545 | |||
}} | |||
* {{medline-title | |||
|title=Signal for Thrombosis with Eltrombopag and Romiplostim: A Disproportionality Analysis of Spontaneous Reports Within VigiBase®. | |||
|date=12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26338346 | |||
|full-text-url=https://sci-hub.do/10.1007/s40264-015-0337-1 | |||
}} | |||
* {{medline-title | |||
|title=Effect of different photoinitiators and reducing agents on cure efficiency and color stability of resin-based composites using different LED wavelengths. | |||
|date=12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26343422 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jdent.2015.08.015 | |||
}} | |||
* {{medline-title | |||
|title=Complex reference value distributions and partitioned reference intervals across the pediatric age range for 14 specialized biochemical markers in the CALIPER cohort of healthy community children and adolescents. | |||
|date=23.10.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26310965 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cca.2015.08.020 | |||
}} | |||
==TRPA1== | |||
* {{medline-title | |||
|title=Important regulatory function of transient receptor potential ankyrin 1 receptors in age-related learning and memory alterations of mice. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327098 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885083 | |||
}} | |||
* {{medline-title | |||
|title=Aging of mouse intervertebral disc and association with back pain. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30936040 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549718 | |||
}} | |||
* {{medline-title | |||
|title=Congeneric variability in lifespan extension and onset of senescence suggest active regulation of aging in response to low temperature. | |||
|date=12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399408 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336457 | |||
}} | |||
* {{medline-title | |||
|title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699 | |||
|full-text-url=https://sci-hub.do/10.1111/nmo.13185 | |||
}} | |||
* {{medline-title | |||
|title=A Caenorhabditis elegans Model Elucidates a Conserved Role for [[TRPA1]]-Nrf Signaling in Reactive α-Dicarbonyl Detoxification. | |||
|date=21.11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27773573 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135008 | |||
}} | |||
* {{medline-title | |||
|title=A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel. | |||
|date=14.02.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23415228 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594097 | |||
}} | |||
==VIM== | |||
* {{medline-title | |||
|title=Establishment and characterization of a fibroblast cell line from postmortem skin of an adult Chinese muntjac (Muntiacus reevesi). | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31898011 | |||
|full-text-url=https://sci-hub.do/10.1007/s11626-019-00422-8 | |||
}} | |||
* {{medline-title | |||
|title=The effect of test modality on dynamic exercise biomarkers in children, adolescents, and young adults. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31353834 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796805 | |||
}} | |||
* {{medline-title | |||
|title=Centenarians Overexpress Pluripotency-Related Genes. | |||
|date=16.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168 | |||
}} | |||
* {{medline-title | |||
|title=Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells. | |||
|date=01.04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27036204 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818421 | |||
}} | |||
* {{medline-title | |||
|title=Assessment of Age-Related Differences in Functional Capacity Using the Virtual Reality Functional Capacity Assessment Tool (VRFCAT). | |||
|date=06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26618145 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657736 | |||
}} | |||
* {{medline-title | |||
|title=Reactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences. | |||
|date=10.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26184673 | |||
|full-text-url=https://sci-hub.do/10.1002/pros.23045 | |||
}} | |||
==ABCG2== | |||
* {{medline-title | |||
|title=Contribution of senescence in human endometrial stromal cells during proliferative phase to embryo receptivity†. | |||
|date=23.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32285109 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313258 | |||
}} | |||
* {{medline-title | |||
|title=[[ABCG2]] rs2231142 variant in hyperuricemia is modified by [[SLC2A9]] and [[SLC22A12]] polymorphisms and cardiovascular risk factors in an elderly community-dwelling population. | |||
|date=17.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32183743 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077001 | |||
}} | |||
* {{medline-title | |||
|title=Morphological and immunohistochemical characteristics of the equine corneal epithelium. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767359 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900071 | |||
}} | |||
* {{medline-title | |||
|title=Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27103634 | |||
|full-text-url=https://sci-hub.do/10.1124/dmd.115.068577 | |||
}} | |||
* {{medline-title | |||
|title=Gene specific epigenetic regulation of hepatic folate transport system is responsible for perturbed cellular folate status during aging and exogenous modulation. | |||
|date=06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26990146 | |||
|full-text-url=https://sci-hub.do/10.1002/mnfr.201500991 | |||
}} | |||
==ACOX1== | |||
* {{medline-title | |||
|title=Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677513 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2019.01.005 | |||
}} | |||
* {{medline-title | |||
|title=Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765501 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889864 | |||
}} | |||
* {{medline-title | |||
|title=Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. | |||
|date=11.07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28545035 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542266 | |||
}} | |||
* {{medline-title | |||
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827 | |||
}} | |||
* {{medline-title | |||
|title=Decreased liver peroxisomal β-oxidation accompanied by changes in brain fatty acid composition in aged rats. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23892932 | |||
|full-text-url=https://sci-hub.do/10.1007/s10072-013-1509-3 | |||
}} | |||
==AGTR1== | |||
* {{medline-title | |||
|title=Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27584680 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008632 | |||
}} | |||
* {{medline-title | |||
|title=Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age. | |||
|date=01.11.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25124854 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329281 | |||
}} | |||
* {{medline-title | |||
|title=Impact of the [[AGTR1]] A1166C polymorphism on subcortical hyperintensities and cognition in healthy older adults. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24981111 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150909 | |||
}} | |||
* {{medline-title | |||
|title=Influence of the [[AGTR1]] A1166C genotype on the progression of arterial stiffness: A 16-year longitudinal study. | |||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23942655 | |||
|full-text-url=https://sci-hub.do/10.1093/ajh/hpt141 | |||
}} | |||
* {{medline-title | |||
|title=Identification of RAS genotypes that modulate blood pressure change by outdoor temperature. | |||
|date=06.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23388887 | |||
|full-text-url=https://sci-hub.do/10.1038/hr.2012.218 | |||
}} | |||
==AIM2== | |||
* {{medline-title | |||
|title=Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of Apc mice. | |||
|date=11.04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28397782 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394268 | |||
}} | |||
* {{medline-title | |||
|title=Reduced levels of cytosolic DNA sensor [[AIM2]] are associated with impaired cytokine responses in healthy elderly. | |||
|date=06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26944367 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2016.02.016 | |||
}} | |||
* {{medline-title | |||
|title=Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448778 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596365 | |||
}} | |||
* {{medline-title | |||
|title=Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26197995 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712099 | |||
}} | |||
* {{medline-title | |||
|title=DAMPs, ageing, and cancer: The 'DAMP Hypothesis'. | |||
|date=11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25446804 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416066 | |||
}} | |||
==ARMS2== | |||
* {{medline-title | |||
|title=Benefits, Potential Harms, and Optimal Use of Nutritional Supplementation for Preventing Progression of Age-Related Macular Degeneration. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27866147 | |||
|full-text-url=https://sci-hub.do/10.1177/1060028016680643 | |||
}} | |||
* {{medline-title | |||
|title=A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging. | |||
|date=14.07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27500671 | |||
|full-text-url=https://sci-hub.do/10.3791/54136 | |||
}} | |||
* {{medline-title | |||
|title=Mesopic Pelli-Robson contrast sensitivity and MP-1 microperimetry in healthy ageing and age-related macular degeneration. | |||
|date=12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27225020 | |||
|full-text-url=https://sci-hub.do/10.1111/aos.13112 | |||
}} | |||
* {{medline-title | |||
|title=[Age-related Macular Degeneration in the Japanese]. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27164756 | |||
}} | |||
* {{medline-title | |||
|title=Prevalence and Genetic Characteristics of Geographic Atrophy among Elderly Japanese with Age-Related Macular Degeneration. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26918864 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769020 | |||
}} | |||
==BAD== | |||
* {{medline-title | |||
|title=I imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway. | |||
|date=31.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33128688 | |||
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00281-2 | |||
}} | |||
* {{medline-title | |||
|title=Xanthohumol exerts protective effects in liver alterations associated with aging. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29536163 | |||
|full-text-url=https://sci-hub.do/10.1007/s00394-018-1657-6 | |||
}} | |||
* {{medline-title | |||
|title=Protective effect of xanthohumol against age-related brain damage. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011 | |||
}} | |||
* {{medline-title | |||
|title=Melatonin decreases the expression of inflammation and apoptosis markers in the lung of a senescence-accelerated mice model. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26656745 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2015.11.021 | |||
}} | |||
* {{medline-title | |||
|title=Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26594596 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642830 | |||
}} | |||
==BMPR2== | |||
* {{medline-title | |||
|title=Human placenta-derived mesenchymal stem cells stimulate ovarian function via miR-145 and bone morphogenetic protein signaling in aged rats. | |||
|date=05.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33153492 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643421 | |||
}} | |||
* {{medline-title | |||
|title=Centenarians Overexpress Pluripotency-Related Genes. | |||
|date=16.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168 | |||
}} | |||
* {{medline-title | |||
|title=Age-related expression of TGF beta family receptors in human cumulus oophorus cells. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28466233 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581779 | |||
}} | |||
* {{medline-title | |||
|title=Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26076038 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496295 | |||
}} | |||
* {{medline-title | |||
|title=Update on pediatric pulmonary arterial hypertension. Differences and similarities to adult disease. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24152725 | |||
|full-text-url=https://sci-hub.do/10.1253/circj.cj-13-1180 | |||
}} | |||
==BPI== | |||
* {{medline-title | |||
|title=High TARC plasma levels confer protection to long living individuals by inducing M2 profile. | |||
|date=01.2021 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002742 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2020.155305 | |||
}} | |||
* {{medline-title | |||
|title=Circulating [[BPI]]FB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32547549 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272600 | |||
}} | |||
* {{medline-title | |||
|title=The effect of postural deformities on back function and pain in patients with Parkinson's disease. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31177242 | |||
|full-text-url=https://sci-hub.do/10.3233/NRE-182637 | |||
}} | |||
* {{medline-title | |||
|title=The expression of the [[BPI]]FB4 and [[CXCR4]] associates with sustained health in long-living individuals from Cilento-Italy. | |||
|date=22.01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28121621 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361669 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent expression of the [[BPI]] gene in Sutai piglets. | |||
|date=28.06.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23661399 | |||
|full-text-url=https://sci-hub.do/10.4238/2012.April.12.1 | |||
}} | |||
==CCL3== | |||
* {{medline-title | |||
|title=Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: Sex differences and role of purinergic receptors. | |||
|date=07.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33166661 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2020.11.013 | |||
}} | |||
* {{medline-title | |||
|title=Microglial translational profiling reveals a convergent [[APOE]] pathway from aging, amyloid, and tau. | |||
|date=03.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082275 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122978 | |||
}} | |||
* {{medline-title | |||
|title=Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760352 | |||
|full-text-url=https://sci-hub.do/10.1620/tjem.245.29 | |||
}} | |||
* {{medline-title | |||
|title=Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29487806 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824071 | |||
}} | |||
* {{medline-title | |||
|title=Changes in the expression of the Toll-like receptor system in the aging rat kidneys. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810370 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014502 | |||
}} | |||
==CCNB1== | |||
* {{medline-title | |||
|title=The antioxidant icariin protects porcine oocytes from age-related damage in vitro. | |||
|date=12.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32777912 | |||
|full-text-url=https://sci-hub.do/10.5713/ajas.20.0046 | |||
}} | |||
* {{medline-title | |||
|title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012 | |||
|full-text-url=https://sci-hub.do/10.1002/mrd.23079 | |||
}} | |||
* {{medline-title | |||
|title=Effect of [[CCNB1]] silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30069972 | |||
|full-text-url=https://sci-hub.do/10.1002/jcp.26816 | |||
}} | |||
* {{medline-title | |||
|title=Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan. | |||
|date=31.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463071 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881094 | |||
}} | |||
* {{medline-title | |||
|title=Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23704896 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660335 | |||
}} | |||
==CCND1== | |||
* {{medline-title | |||
|title=Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592933 | |||
|full-text-url=https://sci-hub.do/10.1016/j.archoralbio.2020.104819 | |||
}} | |||
* {{medline-title | |||
|title=Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31811565 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062590 | |||
}} | |||
* {{medline-title | |||
|title=Expansion of adipose tissue-derived stromal cells at "physiologic" hypoxia attenuates replicative senescence. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28589682 | |||
|full-text-url=https://sci-hub.do/10.1002/cbf.3267 | |||
}} | |||
* {{medline-title | |||
|title=Sporadic colorectal cancer development shows rejuvenescence regarding epithelial proliferation and apoptosis. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24098334 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789736 | |||
}} | |||
* {{medline-title | |||
|title=Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. | |||
|date=15.08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23707792 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mce.2013.05.003 | |||
}} | |||
==CD22== | |||
* {{medline-title | |||
|title=Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32581723 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296093 | |||
}} | |||
* {{medline-title | |||
|title=[[CD22]] blockade restores homeostatic microglial phagocytosis in ageing brains. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944478 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6574119 | |||
}} | |||
* {{medline-title | |||
|title=Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624008 | |||
|full-text-url=https://sci-hub.do/10.24425/119039 | |||
}} | |||
* {{medline-title | |||
|title=Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice. | |||
|date=01.07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25987743 | |||
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1403139 | |||
}} | |||
* {{medline-title | |||
|title=Double negative (CD19 IgG IgD-[[CD27]]-) B lymphocytes: a new insight from telomerase in healthy elderly, in centenarian offspring and in Alzheimer's disease patients. | |||
|date=11.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951896 | |||
|full-text-url=https://sci-hub.do/10.1016/j.imlet.2014.06.003 | |||
}} | |||
==CD2AP== | |||
* {{medline-title | |||
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. | |||
|date=28.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389 | |||
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049 | |||
}} | |||
* {{medline-title | |||
|title=Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. | |||
|date=11.04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28199971 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421828 | |||
}} | |||
* {{medline-title | |||
|title=Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27005436 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005889 | |||
}} | |||
* {{medline-title | |||
|title=HYDRA: Revealing heterogeneity of imaging and genetic patterns through a multiple max-margin discriminative analysis framework. | |||
|date=15.01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26923371 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408358 | |||
}} | |||
* {{medline-title | |||
|title=Dendrin ablation prolongs life span by delaying kidney failure. | |||
|date=08.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26073036 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530132 | |||
}} | |||
==CD81== | |||
* {{medline-title | |||
|title=Ovarian aging increases small extracellular vesicle [[CD81]] release in human follicular fluid and influences miRNA profiles. | |||
|date=17.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554857 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343446 | |||
}} | |||
* {{medline-title | |||
|title=Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature. | |||
|date=15.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32326435 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227017 | |||
}} | |||
* {{medline-title | |||
|title=Increased production of functional small extracellular vesicles in senescent endothelial cells. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32101370 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176858 | |||
}} | |||
* {{medline-title | |||
|title=Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. | |||
|date=12.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32059608 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074517 | |||
}} | |||
* {{medline-title | |||
|title=Extracellular Vesicles Derived from Senescent Fibroblasts Attenuate the Dermal Effect on Keratinocyte Differentiation. | |||
|date=04.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32033114 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037765 | |||
}} | |||
==CES1== | |||
* {{medline-title | |||
|title=[Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog]. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31061351 | |||
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00228 | |||
}} | |||
* {{medline-title | |||
|title=Age-Dependent Absolute Abundance of Hepatic Carboxylesterases ([[CES1]] and [[CES2]]) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27895113 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267516 | |||
}} | |||
* {{medline-title | |||
|title=Identifying clinically relevant sources of variability: The clopidogrel challenge. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27557470 | |||
|full-text-url=https://sci-hub.do/10.1002/cpt.459 | |||
}} | |||
* {{medline-title | |||
|title=Age-Dependent Human Hepatic Carboxylesterase 1 ([[CES1]]) and Carboxylesterase 2 ([[CES2]]) Postnatal Ontogeny. | |||
|date=07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26825642 | |||
|full-text-url=https://sci-hub.do/10.1124/dmd.115.068957 | |||
}} | |||
* {{medline-title | |||
|title=Distinct patterns of aging effects on the expression and activity of carboxylesterases in rat liver and intestine. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24271336 | |||
|full-text-url=https://sci-hub.do/10.1124/dmd.113.054551 | |||
}} | |||
==CFB== | |||
* {{medline-title | |||
|title=Effect of Age on the Efficacy and Safety of Once-Daily Single-Inhaler Triple Therapy Fluticasone Furoate/Umeclidinium/Vilanterol in Patients With Chronic Obstructive Pulmonary Disease: A Post Hoc Analysis of the [[IMPACT]] Trial. | |||
|date=05.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33031829 | |||
|full-text-url=https://sci-hub.do/10.1016/j.chest.2020.09.253 | |||
}} | |||
* {{medline-title | |||
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. | |||
|date=13.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230 | |||
}} | |||
* {{medline-title | |||
|title=Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28325852 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417827 | |||
}} | |||
* {{medline-title | |||
|title=Genetic factors associated with the development of age-related macular degeneration. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27170480 | |||
|full-text-url=https://sci-hub.do/10.1016/j.medici.2016.02.004 | |||
}} | |||
* {{medline-title | |||
|title=Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation. | |||
|date=10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23608111 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706521 | |||
}} | |||
==CLN3== | |||
* {{medline-title | |||
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent alterations in neuronal activity in the hippocampus and visual cortex in a mouse model of Juvenile Neuronal Ceroid Lipofuscinosis ([[CLN3]]). | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28042098 | |||
|full-text-url=https://sci-hub.do/10.1016/j.nbd.2016.12.022 | |||
}} | |||
* {{medline-title | |||
|title=Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease). | |||
|date=15.12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26450516 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654058 | |||
}} | |||
* {{medline-title | |||
|title=Finding the most appropriate mouse model of juvenile [[CLN3]] (Batten) disease for therapeutic studies: the importance of genetic background and gender. | |||
|date=04.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26035843 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381334 | |||
}} | |||
* {{medline-title | |||
|title=Xbp1 directs global repression of budding yeast transcription during the transition to quiescence and is important for the longevity and reversibility of the quiescent state. | |||
|date=10.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24204289 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814307 | |||
}} | |||
==CXCR1== | |||
* {{medline-title | |||
|title=Harmful neutrophil subsets in patients with ischemic stroke: Association with disease severity. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31355307 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624098 | |||
}} | |||
* {{medline-title | |||
|title=Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells. | |||
|date=15.06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28418782 | |||
|full-text-url=https://sci-hub.do/10.1089/scd.2016.0324 | |||
}} | |||
* {{medline-title | |||
|title=The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via [[CXCR1]]-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27769935 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2016.10.011 | |||
}} | |||
* {{medline-title | |||
|title=Habitual physical activity is associated with the maintenance of neutrophil migratory dynamics in healthy older adults. | |||
|date=08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26928196 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929133 | |||
}} | |||
* {{medline-title | |||
|title=Activation profile of [[CXCL8]]-stimulated neutrophils and aging. | |||
|date=03.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23433787 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2013.01.016 | |||
}} | |||
==DKC1== | |||
* {{medline-title | |||
|title=CD8 T-cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with [[PARN]] and [[DKC1]] mutations. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32452087 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521304 | |||
}} | |||
* {{medline-title | |||
|title=Successful liver transplantation in short telomere syndromes without bone marrow failure due to [[DKC1]] mutation. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32166868 | |||
|full-text-url=https://sci-hub.do/10.1111/petr.13695 | |||
}} | |||
* {{medline-title | |||
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655 | |||
}} | |||
* {{medline-title | |||
|title=Cinnamaldehyde and eugenol change the expression folds of [[AKT1]] and [[DKC1]] genes and decrease the telomere length of human adipose-derived stem cells (hASCs): An experimental and in silico study. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28392905 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378970 | |||
}} | |||
* {{medline-title | |||
|title=Molecular adaptation of telomere associated genes in mammals. | |||
|date=15.11.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24237966 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833184 | |||
}} | |||
==DMP1== | |||
* {{medline-title | |||
|title=[[GREM1]] inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. | |||
|date=09.03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151168 | |||
|full-text-url=https://sci-hub.do/10.1080/03008207.2020.1736054 | |||
}} | |||
* {{medline-title | |||
|title=Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978155 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029870 | |||
}} | |||
* {{medline-title | |||
|title=[i]Dmp1[/i] Null Mice Develop a Unique Osteoarthritis-like Phenotype. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27766035 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069442 | |||
}} | |||
* {{medline-title | |||
|title=Decline in calcitonin receptor expression in osteocytes with age. | |||
|date=05.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24516262 | |||
|full-text-url=https://sci-hub.do/10.1530/JOE-13-0524 | |||
}} | |||
* {{medline-title | |||
|title=Novel sandwich ELISAs for rat [[DMP1]]: age-related decrease of circulatory [[DMP1]] levels in male rats. | |||
|date=12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24076023 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bone.2013.09.013 | |||
}} | |||
==DRD4== | |||
* {{medline-title | |||
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children. | |||
|date=04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915 | |||
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711 | |||
}} | |||
* {{medline-title | |||
|title=Age-dependent role of pre- and perinatal factors in interaction with genes on ADHD symptoms across adolescence. | |||
|date=07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28259004 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2017.02.014 | |||
}} | |||
* {{medline-title | |||
|title=Association between dopamine D4 receptor polymorphism and age related changes in brain glucose metabolism. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23717434 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661541 | |||
}} | |||
* {{medline-title | |||
|title=Polymorphic variants of neurotransmitter receptor genes may affect sexual function in aging males: data from the HALS study. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23485949 | |||
|full-text-url=https://sci-hub.do/10.1159/000350324 | |||
}} | |||
* {{medline-title | |||
|title=[[DRD4]] genotype predicts longevity in mouse and human. | |||
|date=02.01.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23283341 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710129 | |||
}} | |||
==DST== | |||
* {{medline-title | |||
|title=Ancestral germen/soma distinction in microbes: Expanding the disposable soma theory of aging to all unicellular lineages. | |||
|date=07.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268207 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101064 | |||
}} | |||
* {{medline-title | |||
|title=Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386173 | |||
|full-text-url=https://sci-hub.do/10.1111/jgs.16089 | |||
}} | |||
* {{medline-title | |||
|title=The associations between diet quality, Body Mass Index (BMI) and Health and Activity Limitation Index (HALex) in the Geisinger Rural Aging Study (GRAS). | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24522469 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550808 | |||
}} | |||
* {{medline-title | |||
|title=Depression-like behavior is dependent on age in male SAMP8 mice. | |||
|date=04.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23559311 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-013-9420-0 | |||
}} | |||
* {{medline-title | |||
|title=Swallowing disorders in nursing home residents: how can the problem be explained? | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23449951 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581290 | |||
}} | |||
==E2F3== | |||
* {{medline-title | |||
|title=Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution. | |||
|date=07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730547 | |||
|full-text-url=https://sci-hub.do/10.1016/j.molimm.2018.04.010 | |||
}} | |||
* {{medline-title | |||
|title=miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions. | |||
|date=01.03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27979858 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374304 | |||
}} | |||
* {{medline-title | |||
|title=Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution. | |||
|date=09.10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25284794 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194175 | |||
}} | |||
* {{medline-title | |||
|title=Tumor-suppressive microRNA-449a induces growth arrest and senescence by targeting [[E2F3]] in human lung cancer cells. | |||
|date=28.03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24211326 | |||
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2013.10.031 | |||
}} | |||
* {{medline-title | |||
|title=Elevated miR-34c-5p mediates dermal fibroblast senescence by ultraviolet irradiation. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23983607 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753410 | |||
}} | |||
==ERAS== | |||
* {{medline-title | |||
|title=Enhanced Recovery After Surgery: Are the Principles Applicable to Adult and Geriatric Acute Care and Trauma Surgery? | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30711234 | |||
|full-text-url=https://sci-hub.do/10.1016/j.anclin.2018.10.001 | |||
}} | |||
* {{medline-title | |||
|title=Prospective application of an implementation framework to improve postoperative nutrition care processes: Evaluation of a mixed methods implementation study. | |||
|date=09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30151938 | |||
|full-text-url=https://sci-hub.do/10.1111/1747-0080.12464 | |||
}} | |||
* {{medline-title | |||
|title=Enhanced Recovery After Surgery ([[ERAS]]) - The Evidence in Geriatric Emergency Surgery: A Systematic Review. | |||
|date=Sept-10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088554 | |||
|full-text-url=https://sci-hub.do/10.21614/chirurgia.112.5.546 | |||
}} | |||
* {{medline-title | |||
|title=Multimodal Rehabilitation in Geriatric Emergency Surgery. | |||
|date=Sept-10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088555 | |||
|full-text-url=https://sci-hub.do/10.21614/chirurgia.112.5.558 | |||
}} | |||
* {{medline-title | |||
|title=Surgical Stress Reduction in Elderly Patients Undergoing Elective Colorectal Laparoscopic Surgery within an [[ERAS]] Protocol. | |||
|date=11-12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28044948 | |||
|full-text-url=https://sci-hub.do/10.21614/chirurgia.111.6.476 | |||
}} | |||
==FBL== | |||
* {{medline-title | |||
|title=APPLICATION OF A NOVEL QUANTITATIVE TRACTOGRAPHY-BASED ANALYSIS OF DIFFUSION TENSOR IMAGING TO EXAMINE FIBER BUNDLE LENGTH IN HUMAN CEREBRAL WHITE MATTER. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27721932 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055128 | |||
}} | |||
* {{medline-title | |||
|title=Cognitive reserve moderates the relationship between neuropsychological performance and white matter fiber bundle length in healthy older adults. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26961092 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083104 | |||
}} | |||
* {{medline-title | |||
|title=Fiber bundle length and cognition: a length-based tractography MRI study. | |||
|date=12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25376332 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424188 | |||
}} | |||
* {{medline-title | |||
|title=White matter changes with age utilizing quantitative diffusion MRI. | |||
|date=15.07.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24928121 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117364 | |||
}} | |||
* {{medline-title | |||
|title=Impact of body mass index on neuronal fiber bundle lengths among healthy older adults. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23564371 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830712 | |||
}} | |||
==FGA== | |||
* {{medline-title | |||
|title=Goal Pursuit, Goal Adjustment, and Pain in Middle-Aged Adults Aging With Physical Disability. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31718416 | |||
|full-text-url=https://sci-hub.do/10.1177/0898264319827142 | |||
}} | |||
* {{medline-title | |||
|title=Tenacious Goal Pursuit, Flexible Goal Adjustment, and Life Satisfaction Among Chinese Older Adult Couples. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31547780 | |||
|full-text-url=https://sci-hub.do/10.1177/0164027519876125 | |||
}} | |||
* {{medline-title | |||
|title=Association of tenacious goal pursuit and flexible goal adjustment with out-of-home mobility among community-dwelling older people. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30449015 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682663 | |||
}} | |||
* {{medline-title | |||
|title=Assimilative and accommodative coping in older adults with and without sensory impairment: four-year change and prospective relations with affective well-being. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30407084 | |||
|full-text-url=https://sci-hub.do/10.1080/13607863.2018.1479833 | |||
}} | |||
* {{medline-title | |||
|title=Age stereotypes, flexible goal adjustment, and well-being among Chinese older adults. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28635315 | |||
|full-text-url=https://sci-hub.do/10.1080/13548506.2017.1344253 | |||
}} | |||
==FOXA1== | |||
* {{medline-title | |||
|title=Analyses of an epigenetic switch involved in the activation of pioneer factor [[FOXA1]] leading to the prognostic value of estrogen receptor and [[FOXA1]] co-expression in breast cancer. | |||
|date=28.09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562808 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782010 | |||
}} | |||
* {{medline-title | |||
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. | |||
|date=05.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244 | |||
}} | |||
* {{medline-title | |||
|title=[[FOXA1]] and [[SOX9]] Expression in the Developing Urogenital Sinus of the Tammar Wallaby (Macropus eugenii). | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26406875 | |||
|full-text-url=https://sci-hub.do/10.1159/000439499 | |||
}} | |||
* {{medline-title | |||
|title=Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. | |||
|date=03.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761685 | |||
|full-text-url=https://sci-hub.do/10.1134/S0006297915030062 | |||
}} | |||
* {{medline-title | |||
|title=Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-[[MADD]] locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. | |||
|date=06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24951664 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066205 | |||
}} | |||
==FOXN1== | |||
* {{medline-title | |||
|title=Thymic rejuvenation via [[FOXN1]]-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation. | |||
|date=17.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32790650 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526556 | |||
}} | |||
* {{medline-title | |||
|title=Role of Bone Marrow Maturity, Insulin-Like Growth Factor 1 Receptor, and Forkhead Box Protein N1 in Thymic Involution and Rejuvenation. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27145342 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097038 | |||
}} | |||
* {{medline-title | |||
|title=Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26983083 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794177 | |||
}} | |||
* {{medline-title | |||
|title=A deletion in [[FOXN1]] is associated with a syndrome characterized by congenital hypotrichosis and short life expectancy in Birman cats. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25781316 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363148 | |||
}} | |||
* {{medline-title | |||
|title=Regeneration of the aged thymus by a single transcription factor. | |||
|date=04.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24715454 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978836 | |||
}} | |||
==FOXO6== | |||
* {{medline-title | |||
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. | |||
|date=15.11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204 | |||
}} | |||
* {{medline-title | |||
|title=Introduction to FOXO Biology. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414140 | |||
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-8900-3_1 | |||
}} | |||
* {{medline-title | |||
|title=FOXO in Neural Cells and Diseases of the Nervous System. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29433734 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881381 | |||
}} | |||
* {{medline-title | |||
|title=FOXO Transcriptional Factors and Long-Term Living. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28894507 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574317 | |||
}} | |||
* {{medline-title | |||
|title=Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26643314 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783344 | |||
}} | |||
==GDF9== | |||
* {{medline-title | |||
|title=Prediction of ovarian aging using ovarian expression of [[BMP15]], [[GDF9]], and C-[[KIT]]. | |||
|date=04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223330 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221484 | |||
}} | |||
* {{medline-title | |||
|title=Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31389140 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826128 | |||
}} | |||
* {{medline-title | |||
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. | |||
|date=18.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463 | |||
}} | |||
* {{medline-title | |||
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490 | |||
|full-text-url=https://sci-hub.do/10.1071/RD14472 | |||
}} | |||
* {{medline-title | |||
|title=Identification of a mutation in [[GDF9]] as a novel cause of diminished ovarian reserve in young women. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23851219 | |||
|full-text-url=https://sci-hub.do/10.1093/humrep/det291 | |||
}} | |||
==GGCT== | |||
* {{medline-title | |||
|title=Blockade of γ-Glutamylcyclotransferase Enhances Docetaxel Growth Inhibition of Prostate Cancer Cells. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31519583 | |||
|full-text-url=https://sci-hub.do/10.21873/anticanres.13666 | |||
}} | |||
* {{medline-title | |||
|title=Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase ([[GGCT]]): A Novel Molecular Target for Anticancer Therapy. | |||
|date=14.07.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30011933 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073726 | |||
}} | |||
* {{medline-title | |||
|title=Depletion of gamma-glutamylcyclotransferase in cancer cells induces autophagy followed by cellular senescence. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29736310 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934555 | |||
}} | |||
* {{medline-title | |||
|title=Prohibitin-2 is a novel regulator of p21 induced by depletion of γ-glutamylcyclotransferase. | |||
|date=29.01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29307834 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.029 | |||
}} | |||
* {{medline-title | |||
|title=Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation. | |||
|date=22.09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27658708 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034417 | |||
}} | |||
==GIT2== | |||
* {{medline-title | |||
|title=The [[RXFP3]] receptor is functionally associated with cellular responses to oxidative stress and DNA damage. | |||
|date=03.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794429 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932917 | |||
}} | |||
* {{medline-title | |||
|title=Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic [[GIT2]] in aging trajectories. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31574270 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111150 | |||
}} | |||
* {{medline-title | |||
|title=[[GIT2]]-A keystone in ageing and age-related disease. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002 | |||
}} | |||
* {{medline-title | |||
|title=Genomic deletion of [[GIT2]] induces a premature age-related thymic dysfunction and systemic immune system disruption. | |||
|date=04.03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28260693 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391227 | |||
}} | |||
* {{medline-title | |||
|title=[[GIT2]] Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26834700 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716144 | |||
}} | |||
==GPX4== | |||
* {{medline-title | |||
|title=l-carnitine supplementation during in vitro culture regulates oxidative stress in embryos from bovine aged oocytes. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31837632 | |||
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2019.11.036 | |||
}} | |||
* {{medline-title | |||
|title=Dietary Selenium Supplementation Ameliorates Female Reproductive Efficiency in Aging Mice. | |||
|date=11.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31835711 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969897 | |||
}} | |||
* {{medline-title | |||
|title=Resveratrol improves in vitro maturation of oocytes in aged mice and humans. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29778389 | |||
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.01.020 | |||
}} | |||
* {{medline-title | |||
|title=Differential menopause- versus aging-induced changes in oxidative stress and circadian rhythm gene markers. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28408140 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.04.002 | |||
}} | |||
* {{medline-title | |||
|title=Maternal obesity in the rat impairs male offspring aging of the testicular antioxidant defence system. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28063465 | |||
|full-text-url=https://sci-hub.do/10.1071/RD16277 | |||
}} | |||
==GRK2== | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 2 modifies the ability of Caenorhabditis elegans to survive oxidative stress. | |||
|date=16.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33064264 | |||
|full-text-url=https://sci-hub.do/10.1007/s12192-020-01168-z | |||
}} | |||
* {{medline-title | |||
|title=G protein coupled receptor kinases modulate Caenorhabditis elegans reactions to heat stresses. | |||
|date=01.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32768194 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.07.121 | |||
}} | |||
* {{medline-title | |||
|title=Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging. | |||
|date=01.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32216616 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346533 | |||
}} | |||
* {{medline-title | |||
|title=Senescent Cells Differentially Translate Senescence-Related mRNAs Via Ribosome Heterogeneity. | |||
|date=18.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30285098 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/gly228 | |||
}} | |||
* {{medline-title | |||
|title=Effects of exercise training on cardiovascular adrenergic system. | |||
|date=28.11.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24348425 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842896 | |||
}} | |||
==HAS2== | |||
* {{medline-title | |||
|title=Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32651107 | |||
|full-text-url=https://sci-hub.do/10.1016/j.rbmo.2020.04.006 | |||
}} | |||
* {{medline-title | |||
|title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508 | |||
|full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7 | |||
}} | |||
* {{medline-title | |||
|title=Microvasculature of the Mouse Cerebral Cortex Exhibits Increased Accumulation and Synthesis of Hyaluronan With Aging. | |||
|date=01.06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28482035 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075594 | |||
}} | |||
* {{medline-title | |||
|title=Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. | |||
|date=09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26987798 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383204 | |||
}} | |||
* {{medline-title | |||
|title=Age-associated changes in gene expression of goat oocytes. | |||
|date=01.09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23746875 | |||
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2013.04.019 | |||
}} | |||
==HCN2== | |||
* {{medline-title | |||
|title=Protein expression changes of [[HCN1]] and [[HCN2]] in hippocampal subregions of gerbils during the normal aging process. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32128096 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038419 | |||
}} | |||
* {{medline-title | |||
|title=Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes. | |||
|date=11.11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26379059 | |||
|full-text-url=https://sci-hub.do/10.1097/WNR.0000000000000455 | |||
}} | |||
* {{medline-title | |||
|title=Age-associated expression of HCN channel isoforms in rat sinoatrial node. | |||
|date=02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341471 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935443 | |||
}} | |||
* {{medline-title | |||
|title=Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation. | |||
|date=09.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26005035 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526032 | |||
}} | |||
* {{medline-title | |||
|title=Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. | |||
|date=27.02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761792 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352274 | |||
}} | |||
==HSPA8== | |||
* {{medline-title | |||
|title=Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31733664 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939615 | |||
}} | |||
* {{medline-title | |||
|title=Influence of Normal Aging on Brain Autophagy: A Complex Scenario. | |||
|date=2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30914945 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421305 | |||
}} | |||
* {{medline-title | |||
|title=Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone [[HSPA8]] and the ubiquitin ligase UBE2D. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30368041 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202877 | |||
}} | |||
* {{medline-title | |||
|title=Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29867441 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952035 | |||
}} | |||
* {{medline-title | |||
|title=Age-Related Decrease in Heat Shock 70-kDa Protein 8 in Cerebrospinal Fluid Is Associated with Increased Oxidative Stress. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27507943 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960228 | |||
}} | |||
==IDH1== | |||
* {{medline-title | |||
|title=Oxidative Damage to the TCA Cycle Enzyme [[MDH1]] Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. | |||
|date=03.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32175745 | |||
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00861 | |||
}} | |||
* {{medline-title | |||
|title=An integrated metabolomic and gene expression analysis identifies heat and calcium metabolic networks underlying postharvest sweet cherry fruit senescence. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31531781 | |||
|full-text-url=https://sci-hub.do/10.1007/s00425-019-03272-6 | |||
}} | |||
* {{medline-title | |||
|title=GBM-associated mutations and altered protein expression are more common in young patients. | |||
|date=25.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27579614 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342491 | |||
}} | |||
* {{medline-title | |||
|title=[[IDH1]] Associated with Neuronal Apoptosis in Adult Rats Brain Following Intracerebral Hemorrhage. | |||
|date=07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27568302 | |||
|full-text-url=https://sci-hub.do/10.1007/s10571-016-0421-9 | |||
}} | |||
* {{medline-title | |||
|title=2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. | |||
|date=01.09.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26190651 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663076 | |||
}} | |||
==IRS2== | |||
* {{medline-title | |||
|title=Effects of Heshouwuyin on gene expression of the insulin/IGF signalling pathway in rat testis and spermatogenic cells. | |||
|date=12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33264567 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717869 | |||
}} | |||
* {{medline-title | |||
|title=Involvement of insulin receptor substrates in cognitive impairment and Alzheimer's disease. | |||
|date=08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30964050 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524492 | |||
}} | |||
* {{medline-title | |||
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486 | |||
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014 | |||
}} | |||
* {{medline-title | |||
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 | |||
}} | |||
* {{medline-title | |||
|title=Analysis of [[MTNR1B]] gene polymorphisms in relationship with [[IRS2]] gene variants, epicardial fat thickness, glucose homeostasis and cognitive performance in the elderly. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708046 | |||
|full-text-url=https://sci-hub.do/10.1080/07420528.2017.1340894 | |||
}} | |||
==KCNB1== | |||
* {{medline-title | |||
|title=Oxidation of [[KCNB1]] potassium channels in the murine brain during aging is associated with cognitive impairment. | |||
|date=14.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922570 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471606 | |||
}} | |||
* {{medline-title | |||
|title=Oxidation of [[KCNB1]] Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury. | |||
|date=26.10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27798188 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098843 | |||
}} | |||
* {{medline-title | |||
|title=Oxidation of K( ) Channels in Aging and Neurodegeneration. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27114846 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809605 | |||
}} | |||
* {{medline-title | |||
|title=Oxidation of [[KCNB1]] K( ) channels in central nervous system and beyond. | |||
|date=26.05.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24921000 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050120 | |||
}} | |||
* {{medline-title | |||
|title=Molecular mechanisms underlying the apoptotic effect of [[KCNB1]] K channel oxidation. | |||
|date=08.02.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23275378 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567663 | |||
}} | |||
==KISS1== | |||
* {{medline-title | |||
|title=In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520345 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09834-1 | |||
}} | |||
* {{medline-title | |||
|title=Kisspeptin level in the aging ovary is regulated by the sympathetic nervous system. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27856623 | |||
|full-text-url=https://sci-hub.do/10.1530/JOE-16-0181 | |||
}} | |||
* {{medline-title | |||
|title=Kisspeptin across the human lifespan:evidence from animal studies and beyond. | |||
|date=06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27340201 | |||
|full-text-url=https://sci-hub.do/10.1530/JOE-15-0538 | |||
}} | |||
* {{medline-title | |||
|title=Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25765287 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475460 | |||
}} | |||
* {{medline-title | |||
|title=[Profiles of reproduction-related mRNA expressions in hypothalamus of female mice with advancing age]. | |||
|date=17.12.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24548401 | |||
}} | |||
==LIF== | |||
* {{medline-title | |||
|title=Use of the Reversible Myogenic to Lipogenic Transdifferentiation Switch for the Design of Pre-clinical Drug Screening in Idiopathic Pulmonary Fibrosis. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33042971 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523217 | |||
}} | |||
* {{medline-title | |||
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity. | |||
|date=25.06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174 | |||
}} | |||
* {{medline-title | |||
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. | |||
|date=15.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304 | |||
}} | |||
* {{medline-title | |||
|title=Assaying human neutrophil elastase activity by capillary zone electrophoresis combined with laser-induced fluorescence. | |||
|date=06.11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26454788 | |||
|full-text-url=https://sci-hub.do/10.1016/j.chroma.2015.09.084 | |||
}} | |||
* {{medline-title | |||
|title=iPSCs, aging and age-related diseases. | |||
|date=25.09.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24784583 | |||
|full-text-url=https://sci-hub.do/10.1016/j.nbt.2014.04.004 | |||
}} | |||
==LONP1== | |||
* {{medline-title | |||
|title=Improved mitochondrial stress response in long-lived Snell dwarf mice. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31423721 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826134 | |||
}} | |||
* {{medline-title | |||
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence. | |||
|date=15.03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833 | |||
}} | |||
* {{medline-title | |||
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. | |||
|date=01.02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068 | |||
}} | |||
* {{medline-title | |||
|title=Mitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disorders. | |||
|date=11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27387767 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183306 | |||
}} | |||
* {{medline-title | |||
|title=Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer. | |||
|date=10-12.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27308364 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905204 | |||
}} | |||
==MAPK14== | |||
* {{medline-title | |||
|title=Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31811565 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062590 | |||
}} | |||
* {{medline-title | |||
|title=Chlorella vulgaris modulates the expression of senescence-associated genes in replicative senescence of human diploid fibroblasts. | |||
|date=01.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642042 | |||
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05140-8 | |||
}} | |||
* {{medline-title | |||
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. | |||
|date=10.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720 | |||
}} | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 | |||
}} | |||
* {{medline-title | |||
|title=Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts. | |||
|date=11-12.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26794818 | |||
|full-text-url=https://sci-hub.do/10.7417/T.2015.1902 | |||
}} | |||
==MARCKS== | |||
* {{medline-title | |||
|title=Ser46-Phosphorylated [[MARCKS]] Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. | |||
|date=07-08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225354 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140116 | |||
}} | |||
* {{medline-title | |||
|title=[[MARCKS]] contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis. | |||
|date=21.06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27081703 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122339 | |||
}} | |||
* {{medline-title | |||
|title=[[MARCKS]]-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging. | |||
|date=10.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26010231 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568964 | |||
}} | |||
* {{medline-title | |||
|title=The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release. | |||
|date=10.02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25761522 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348107 | |||
}} | |||
* {{medline-title | |||
|title=Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of [[MARCKS]]. | |||
|date=04.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23434911 | |||
|full-text-url=https://sci-hub.do/10.1038/nn.3342 | |||
}} | |||
==MGP== | |||
* {{medline-title | |||
|title=Circulating Vitamin K Is Inversely Associated with Incident Cardiovascular Disease Risk among Those Treated for Hypertension in the Health, Aging, and Body Composition Study (Health ABC). | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28356433 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404216 | |||
}} | |||
* {{medline-title | |||
|title=Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma. | |||
|date=21.12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28058013 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175245 | |||
}} | |||
* {{medline-title | |||
|title=[Bone metabolism and cardiovascular function update. Cross link of hypertension, bone loss and vascular calcification - common back grounds in renin angiotensin system with anti-aging aspect -]. | |||
|date=07.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24976056 | |||
|full-text-url=https://sci-hub.do/CliCa140710211030 | |||
}} | |||
* {{medline-title | |||
|title=Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24210635 | |||
|full-text-url=https://sci-hub.do/10.1016/j.maturitas.2013.10.008 | |||
}} | |||
* {{medline-title | |||
|title=Elastin haploinsufficiency impedes the progression of arterial calcification in [[MGP]]-deficient mice. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23857752 | |||
|full-text-url=https://sci-hub.do/10.1002/jbmr.2039 | |||
}} | |||
==MLKL== | |||
* {{medline-title | |||
|title=Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. | |||
|date=18.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33206046 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673785 | |||
}} | |||
* {{medline-title | |||
|title=Remifentanil preconditioning protects against hypoxia-induced senescence and necroptosis in human cardiac myocytes [i]in vitro[/i]. | |||
|date=25.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32584786 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425462 | |||
}} | |||
* {{medline-title | |||
|title=Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. | |||
|date=05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31981738 | |||
|full-text-url=https://sci-hub.do/10.1016/j.joca.2020.01.004 | |||
}} | |||
* {{medline-title | |||
|title=Necroptosis increases with age and is reduced by dietary restriction. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696779 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052392 | |||
}} | |||
* {{medline-title | |||
|title=[[RIPK1]]-[[RIPK3]]-[[MLKL]]-dependent necrosis promotes the aging of mouse male reproductive system. | |||
|date=15.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28807105 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557593 | |||
}} | |||
==MLN== | |||
* {{medline-title | |||
|title=Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849526 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432217 | |||
}} | |||
* {{medline-title | |||
|title=Variability of Spleen and Mesenteric Lymph Node in Control Cynomolgus Monkeys ( Macaca fascicularis) from Nonclinical Safety Studies: A Retrospective Assessment. | |||
|date=01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30563426 | |||
|full-text-url=https://sci-hub.do/10.1177/0192623318809073 | |||
}} | |||
* {{medline-title | |||
|title=Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life. | |||
|date=03.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30523311 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375790 | |||
}} | |||
* {{medline-title | |||
|title=Immunological Basis for Rapid Progression of Diabetes in Older NOD Mouse Recipients Post BM-HSC Transplantation. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26020954 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447290 | |||
}} | |||
* {{medline-title | |||
|title=Association between Mycobacterium avium subspecies paratuberculosis and lymph node size in New Zealand farmed deer (Cervus elaphus). | |||
|date=05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23442016 | |||
|full-text-url=https://sci-hub.do/10.1080/00480169.2012.755886 | |||
}} | |||
==NBR1== | |||
* {{medline-title | |||
|title=Autophagy receptor [[OPTN]] (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing [[FABP3]]. | |||
|date=04.11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143524 | |||
|full-text-url=https://sci-hub.do/10.1080/15548627.2020.1839286 | |||
}} | |||
* {{medline-title | |||
|title=New insights into At[[NBR1]] as a selective autophagy cargo receptor in Arabidopsis. | |||
|date=30.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33124509 | |||
|full-text-url=https://sci-hub.do/10.1080/15592324.2020.1839226 | |||
}} | |||
* {{medline-title | |||
|title=[[SQSTM1]]/p62 and [[PPARGC1A]]/PGC-1alpha at the interface of autophagy and vascular senescence. | |||
|date=06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441382 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469683 | |||
}} | |||
* {{medline-title | |||
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049 | |||
}} | |||
* {{medline-title | |||
|title=Overweight in elderly people induces impaired autophagy in skeletal muscle. | |||
|date=09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28549989 | |||
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2017.05.018 | |||
}} | |||
==NEDD8== | |||
* {{medline-title | |||
|title=Targeting Protein Neddylation for Cancer Therapy. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31898235 | |||
|full-text-url=https://sci-hub.do/10.1007/978-981-15-1025-0_18 | |||
}} | |||
* {{medline-title | |||
|title=Effective targeting of the ubiquitin-like modifier [[NEDD8]] for lung adenocarcinoma treatment. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31907687 | |||
|full-text-url=https://sci-hub.do/10.1007/s10565-019-09503-6 | |||
}} | |||
* {{medline-title | |||
|title=Pevonedistat targeted therapy inhibits canine melanoma cell growth through induction of DNA re-replication and senescence. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665821 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473101 | |||
}} | |||
* {{medline-title | |||
|title=Protein neddylation and its alterations in human cancers for targeted therapy. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29331584 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829022 | |||
}} | |||
* {{medline-title | |||
|title=Targeting protein neddylation with an [[NEDD8]]-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25782162 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4623239 | |||
}} | |||
==NFE2L2== | |||
* {{medline-title | |||
|title=The double-edged sword of [[MTOR]] in autophagy deficiency induced-liver injury and tumorigenesis. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31216956 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693464 | |||
}} | |||
* {{medline-title | |||
|title=The Association of a Single-Nucleotide Polymorphism in the Nuclear Factor (Erythroid-Derived 2)-Like 2 Gene With Adverse Drug Reactions, Multimorbidity, and Frailty in Older People. | |||
|date=22.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102514 | |||
|full-text-url=https://sci-hub.do/10.1093/gerona/glz131 | |||
}} | |||
* {{medline-title | |||
|title=Immunohistochemical localization of Nrf2 in the human cochlea. | |||
|date=01.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29981724 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231984 | |||
}} | |||
* {{medline-title | |||
|title=Lifespan extension by peroxidase and dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in [i]C. elegans[/i]. | |||
|date=01.08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28676501 | |||
|full-text-url=https://sci-hub.do/10.1242/jcs.202119 | |||
}} | |||
* {{medline-title | |||
|title=Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. | |||
|date=02.11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26391655 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824610 | |||
}} | |||
==NPC2== | |||
* {{medline-title | |||
|title=Attenuation of the Niemann-Pick type [[C2]] disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29655638 | |||
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2018.04.001 | |||
}} | |||
* {{medline-title | |||
|title=Quantification of age-related changes of α-tocopherol in lysosomal membranes in murine tissues and human fibroblasts. | |||
|date=05.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27095633 | |||
|full-text-url=https://sci-hub.do/10.1002/biof.1274 | |||
}} | |||
* {{medline-title | |||
|title=Systemic administration of 2-hydroxypropyl-β-cyclodextrin to symptomatic Npc1-deficient mice slows cholesterol sequestration in the major organs and improves liver function. | |||
|date=10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25115571 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526211 | |||
}} | |||
* {{medline-title | |||
|title=Niemann-Pick C disease gene mutations and age-related neurodegenerative disorders. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24386122 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875432 | |||
}} | |||
* {{medline-title | |||
|title=Ontogenic changes in lung cholesterol metabolism, lipid content, and histology in mice with Niemann-Pick type C disease. | |||
|date=01.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24076310 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849124 | |||
}} | |||
==NRG1== | |||
* {{medline-title | |||
|title=Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis. | |||
|date=29.07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27469430 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965755 | |||
}} | |||
* {{medline-title | |||
|title=Neuregulin-1 Administration Protocols Sufficient for Stimulating Cardiac Regeneration in Young Mice Do Not Induce Somatic, Organ, or Neoplastic Growth. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27175488 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866786 | |||
}} | |||
* {{medline-title | |||
|title=Neuregulin 1 improves glucose tolerance in adult and old rats. | |||
|date=04.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26404652 | |||
|full-text-url=https://sci-hub.do/10.1016/j.diabet.2015.08.003 | |||
}} | |||
* {{medline-title | |||
|title=Disruption of hippocampal neuregulin 1-ErbB4 signaling contributes to the hippocampus-dependent cognitive impairment induced by isoflurane in aged mice. | |||
|date=07.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589481 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062586 | |||
}} | |||
* {{medline-title | |||
|title=ErbB2 receptor over-expression improves post-traumatic peripheral nerve regeneration in adult mice. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23437108 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578860 | |||
}} | |||
==PDE4D== | |||
* {{medline-title | |||
|title=Phosphodiesterase [[PDE4D]] Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33192469 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655962 | |||
}} | |||
* {{medline-title | |||
|title=Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function. | |||
|date=02.12.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30409425 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.180 | |||
}} | |||
* {{medline-title | |||
|title=The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation. | |||
|date=08.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28438557 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbi.2017.04.015 | |||
}} | |||
* {{medline-title | |||
|title=Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. | |||
|date=07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25786490 | |||
|full-text-url=https://sci-hub.do/10.1071/RD14472 | |||
}} | |||
* {{medline-title | |||
|title=Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24184653 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2013.10.007 | |||
}} | |||
==PDF== | |||
* {{medline-title | |||
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models. | |||
|date=28.05.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415 | |||
}} | |||
* {{medline-title | |||
|title=Drosophila Clock Is Required in Brain Pacemaker Neurons to Prevent Premature Locomotor Aging Independently of Its Circadian Function. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28072817 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224980 | |||
}} | |||
* {{medline-title | |||
|title=SnapShot: Neuronal Regulation of Aging. | |||
|date=28.07.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27471972 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cell.2016.07.022 | |||
}} | |||
* {{medline-title | |||
|title=Recent data on Mediterranean diet, cardiovascular disease, cancer, diabetes and life expectancy. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26084734 | |||
|full-text-url=https://sci-hub.do/10.4149/bll_2015_065 | |||
}} | |||
* {{medline-title | |||
|title=Pigment-dispersing factor is involved in age-dependent rhythm changes in Drosophila melanogaster. | |||
|date=12.2012 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23223368 | |||
|full-text-url=https://sci-hub.do/10.1177/0748730412462206 | |||
}} | |||
==PIN1== | |||
* {{medline-title | |||
|title=Brain somatic mutations observed in Alzheimer's disease associated with aging and dysregulation of tau phosphorylation. | |||
|date=12.07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31300647 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626023 | |||
}} | |||
* {{medline-title | |||
|title=Class XI Myosins Contribute to Auxin Response and Senescence-Induced Cell Death in [i]Arabidopsis[/i]. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30538710 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277483 | |||
}} | |||
* {{medline-title | |||
|title=Effects of Melatonin and Its Underlying Mechanism on Ethanol-Stimulated Senescence and Osteoclastic Differentiation in Human Periodontal Ligament Cells and Cementoblasts. | |||
|date=12.06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29895782 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032161 | |||
}} | |||
* {{medline-title | |||
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201 | |||
}} | |||
* {{medline-title | |||
|title=Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy. | |||
|date=03.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27612437 | |||
|full-text-url=https://sci-hub.do/10.1002/stem.2495 | |||
}} | |||
==PLAU== | |||
* {{medline-title | |||
|title=Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging. | |||
|date=11.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33031577 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681068 | |||
}} | |||
* {{medline-title | |||
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 | |||
}} | |||
* {{medline-title | |||
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. | |||
|date=11.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004 | |||
}} | |||
* {{medline-title | |||
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. | |||
|date=15.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352 | |||
}} | |||
* {{medline-title | |||
|title=Functional networks of aging markers in the glomeruli of IgA nephropathy: a new therapeutic opportunity. | |||
|date=07.06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27127888 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085107 | |||
}} | |||
==POLD1== | |||
* {{medline-title | |||
|title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes. | |||
|date=10.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529 | |||
}} | |||
* {{medline-title | |||
|title=[[POLD1]] deficiency is involved in cognitive function impairment in AD patients and SAMP8 mice. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30978525 | |||
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2019.108833 | |||
}} | |||
* {{medline-title | |||
|title=[[E2F1]] mediates the downregulation of [[POLD1]] in replicative senescence. | |||
|date=07.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30895337 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588650 | |||
}} | |||
* {{medline-title | |||
|title=Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing. | |||
|date=03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29208544 | |||
|full-text-url=https://sci-hub.do/10.1016/j.arr.2017.12.001 | |||
}} | |||
* {{medline-title | |||
|title=[[POLD1]]: Central mediator of DNA replication and repair, and implication in cancer and other pathologies. | |||
|date=15.09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27320729 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969162 | |||
}} | |||
==POU5F1== | |||
* {{medline-title | |||
|title=Cell quality evaluation with gene expression analysis of spheroids (3D) and adherent (2D) adipose stem cells. | |||
|date=24.10.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33148459 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2020.145269 | |||
}} | |||
* {{medline-title | |||
|title=Enhanced proliferative capacity of human preadipocytes achieved by an optimized cultivating method that induces transient activity of hTERT. | |||
|date=20.08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32703451 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.06.019 | |||
}} | |||
* {{medline-title | |||
|title=Autophagic homeostasis is required for the pluripotency of cancer stem cells. | |||
|date=02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27929731 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324853 | |||
}} | |||
* {{medline-title | |||
|title=Characterization of the [[POU5F1]] Homologue in Nile Tilapia: From Expression Pattern to Biological Activity. | |||
|date=15.09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27473876 | |||
|full-text-url=https://sci-hub.do/10.1089/scd.2016.0143 | |||
}} | |||
* {{medline-title | |||
|title=Determination phase at transition of gonocytes to spermatogonial stem cells improves establishment efficiency of spermatogonial stem cells in domestic cats. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26411537 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685225 | |||
}} | |||
==PRMT1== | |||
* {{medline-title | |||
|title=Reactive oxygen species extend insect life span using components of the insulin-signaling pathway. | |||
|date=12.09.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847950 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604040 | |||
}} | |||
* {{medline-title | |||
|title=Regenerating muscle with arginine methylation. | |||
|date=27.05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28301308 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501374 | |||
}} | |||
* {{medline-title | |||
|title=Simultaneous ablation of prmt-1 and prmt-5 abolishes asymmetric and symmetric arginine dimethylations in Caenorhabditis elegans. | |||
|date=01.06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28158808 | |||
|full-text-url=https://sci-hub.do/10.1093/jb/mvw101 | |||
}} | |||
* {{medline-title | |||
|title=Caveolin1/protein arginine methyltransferase1/sirtuin1 axis as a potential target against endothelial dysfunction. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28126510 | |||
|full-text-url=https://sci-hub.do/10.1016/j.phrs.2017.01.022 | |||
}} | |||
* {{medline-title | |||
|title=Epigallocatechin-3-gallate ameliorates erectile function in aged rats via regulation of [[PRMT1]]/DDAH/ADMA/NOS metabolism pathway. | |||
|date=05-06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27080477 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427783 | |||
}} | |||
==RACK1== | |||
* {{medline-title | |||
|title=Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging. | |||
|date=05.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31636180 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842600 | |||
}} | |||
* {{medline-title | |||
|title=Role of Hormones in the Regulation of [[RACK1]] Expression as a Signaling Checkpoint in Immunosenescence. | |||
|date=06.07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28684670 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535944 | |||
}} | |||
* {{medline-title | |||
|title=Transcriptional regulation of [[RACK1]] and modulation of its expression: Role of steroid hormones and significance in health and aging. | |||
|date=07.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28192162 | |||
|full-text-url=https://sci-hub.do/10.1016/j.cellsig.2017.02.010 | |||
}} | |||
* {{medline-title | |||
|title=Role of androgens in dhea-induced rack1 expression and cytokine modulation in monocytes. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27239218 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884617 | |||
}} | |||
* {{medline-title | |||
|title=Immunostimulatory effects of [[RACK1]] pseudosubstrate in human leukocytes obtained from young and old donors. | |||
|date=30.03.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25779661 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466631 | |||
}} | |||
==REN== | |||
* {{medline-title | |||
|title=In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. | |||
|date=12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520345 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09834-1 | |||
}} | |||
* {{medline-title | |||
|title=The Hispanic Paradox: Race/Ethnicity and Nativity, Immigrant Enclave Residence and Cognitive Impairment Among Older US Adults. | |||
|date=05.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28369694 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435528 | |||
}} | |||
* {{medline-title | |||
|title=Analysis of Clinical Features and Outcomes of Skull Base Chordoma in Different Age-Groups. | |||
|date=08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27237421 | |||
|full-text-url=https://sci-hub.do/10.1016/j.wneu.2016.05.035 | |||
}} | |||
* {{medline-title | |||
|title=Effects of advanced age and renal dysfunction on the single- and repeated-dose pharmacokinetics of modified-release flupirtine. | |||
|date=03.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25613539 | |||
|full-text-url=https://sci-hub.do/10.5414/CP202236 | |||
}} | |||
* {{medline-title | |||
|title=Mapping nutrient resorption efficiencies of subarctic cryptogams and seed plants onto the Tree of Life. | |||
|date=06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25360262 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201435 | |||
}} | |||
==RHO== | |||
* {{medline-title | |||
|title=Conditional reprogramming: next generation cell culture. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32963937 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488362 | |||
}} | |||
* {{medline-title | |||
|title=SARS-CoV-2 receptor [[ACE2]] and [[TMPRSS2]] are primarily expressed in bronchial transient secretory cells. | |||
|date=18.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32246845 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232010 | |||
}} | |||
* {{medline-title | |||
|title=Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging. | |||
|date=28.09.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30274229 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210377 | |||
}} | |||
* {{medline-title | |||
|title=NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through [i]memo-1[/i] in [i]C. elegans[/i]. | |||
|date=13.01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28085666 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235354 | |||
}} | |||
* {{medline-title | |||
|title=Guanine nucleotide exchange factor OSG-1 confers functional aging via dysregulated Rho signaling in Caenorhabditis elegans neurons. | |||
|date=02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25527286 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317656 | |||
}} | |||
==RICTOR== | |||
* {{medline-title | |||
|title=Proteomics of Long-Lived Mammals. | |||
|date=03.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31737995 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117992 | |||
}} | |||
* {{medline-title | |||
|title=Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. | |||
|date=11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31476350 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059097 | |||
}} | |||
* {{medline-title | |||
|title=The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging. | |||
|date=16.08.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27486771 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288141 | |||
}} | |||
* {{medline-title | |||
|title=Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan. | |||
|date=10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25059582 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172536 | |||
}} | |||
* {{medline-title | |||
|title=Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry. | |||
|date=02.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24589862 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366598 | |||
}} | |||
==RPE65== | |||
* {{medline-title | |||
|title=Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells. | |||
|date=08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30091312 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085187 | |||
}} | |||
* {{medline-title | |||
|title=Age-related macular degeneration phenotypes are associated with increased tumor necrosis-alpha and subretinal immune cells in aged Cxcr5 knockout mice. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28282423 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345864 | |||
}} | |||
* {{medline-title | |||
|title=The amino acid transporter [[SLC36A4]] regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling. | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28083894 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334531 | |||
}} | |||
* {{medline-title | |||
|title=Thinning of the [[RPE]] and choroid associated with T lymphocyte recruitment in aged and light-challenged mice. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26392743 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558476 | |||
}} | |||
* {{medline-title | |||
|title=Update on current and future novel therapies for dry age-related macular degeneration. | |||
|date=09.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23971874 | |||
|full-text-url=https://sci-hub.do/10.1586/17512433.2013.829645 | |||
}} | |||
==SDHB== | |||
* {{medline-title | |||
|title=Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature. | |||
|date=15.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32326435 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227017 | |||
}} | |||
* {{medline-title | |||
|title=Oxidative Damage to the TCA Cycle Enzyme [[MDH1]] Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. | |||
|date=03.04.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32175745 | |||
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00861 | |||
}} | |||
* {{medline-title | |||
|title=Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. | |||
|date=12.02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32059608 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074517 | |||
}} | |||
* {{medline-title | |||
|title=Mitochondrial bioenergetics and disease in Caenorhabditis elegans. | |||
|date=01.01.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25553447 | |||
|full-text-url=https://sci-hub.do/10.2741/4305 | |||
}} | |||
* {{medline-title | |||
|title=Long-term prognosis of patients with pediatric pheochromocytoma. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24169644 | |||
|full-text-url=https://sci-hub.do/10.1530/ERC-13-0415 | |||
}} | |||
==SFRP1== | |||
* {{medline-title | |||
|title=[Role and alterations of DNA methylation during the aging and cancer]. | |||
|date=01.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647 | |||
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927 | |||
}} | |||
* {{medline-title | |||
|title=Age-related increase in Wnt inhibitor causes a senescence-like phenotype in human cardiac stem cells. | |||
|date=03.06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28435069 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.04.110 | |||
}} | |||
* {{medline-title | |||
|title=Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma. | |||
|date=21.12.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28058013 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175245 | |||
}} | |||
* {{medline-title | |||
|title=The intrinsic stiffness of human trabecular meshwork cells increases with senescence. | |||
|date=20.06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25915531 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558157 | |||
}} | |||
* {{medline-title | |||
|title=Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24184314 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877168 | |||
}} | |||
==SMAD4== | |||
* {{medline-title | |||
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient. | |||
|date=09.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125 | |||
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7 | |||
}} | |||
* {{medline-title | |||
|title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type p53. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985 | |||
}} | |||
* {{medline-title | |||
|title=iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation. | |||
|date=01.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28708522 | |||
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.06.014 | |||
}} | |||
* {{medline-title | |||
|title=miR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4. | |||
|date=01.08.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26215566 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536309 | |||
}} | |||
* {{medline-title | |||
|title=Loss of smad4 in Sertoli and Leydig cells leads to testicular dysgenesis and hemorrhagic tumor formation in mice. | |||
|date=03.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24501173 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076392 | |||
}} | |||
==SMN2== | |||
* {{medline-title | |||
|title=Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. | |||
|date=01.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589162 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819103 | |||
}} | |||
* {{medline-title | |||
|title=Type 0 Spinal Muscular Atrophy: Further Delineation of Prenatal and Postnatal Features in 16 Patients. | |||
|date=29.11.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27911332 | |||
|full-text-url=https://sci-hub.do/10.3233/JND-160177 | |||
}} | |||
* {{medline-title | |||
|title=Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy. | |||
|date=27.09.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27621445 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047168 | |||
}} | |||
* {{medline-title | |||
|title=Motor neuron disease. [[SMN2]] splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy. | |||
|date=08.08.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25104390 | |||
|full-text-url=https://sci-hub.do/10.1126/science.1250127 | |||
}} | |||
* {{medline-title | |||
|title=Development and characterization of an [[SMN2]]-based intermediate mouse model of Spinal Muscular Atrophy. | |||
|date=01.05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23390132 | |||
|full-text-url=https://sci-hub.do/10.1093/hmg/ddt037 | |||
}} | |||
==SMS== | |||
* {{medline-title | |||
|title=Does a Live Performance Impact Synchronization to Musical Rhythm in Cognitively Impaired Elderly? | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33104027 | |||
|full-text-url=https://sci-hub.do/10.3233/JAD-200521 | |||
}} | |||
* {{medline-title | |||
|title=Testing the effectiveness of physical activity advice delivered via text messaging vs. human phone advisors in a Latino population: The On The Move randomized controlled trial design and methods. | |||
|date=08.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659437 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351675 | |||
}} | |||
* {{medline-title | |||
|title=Mobile Health Interventions for Physical Activity, Sedentary Behavior, and Sleep in Adults Aged 50 Years and Older: A Systematic Literature Review. | |||
|date=01.08.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30507266 | |||
|full-text-url=https://sci-hub.do/10.1123/japa.2017-0410 | |||
}} | |||
* {{medline-title | |||
|title=Senescence-messaging secretome factors trigger premature senescence in human endometrium-derived stem cells. | |||
|date=19.02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397942 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.163 | |||
}} | |||
* {{medline-title | |||
|title=PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice. | |||
|date=13.05.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24778222 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024885 | |||
}} | |||
==SOCS1== | |||
* {{medline-title | |||
|title=Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. | |||
|date=06.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30656452 | |||
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0607-9 | |||
}} | |||
* {{medline-title | |||
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes. | |||
|date=28.10.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560 | |||
}} | |||
* {{medline-title | |||
|title=Daily Socs1 rhythms alter with aging differentially in peripheral clocks in male Wistar rats: therapeutic effects of melatonin. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28331994 | |||
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9687-7 | |||
}} | |||
* {{medline-title | |||
|title=Differential response to intrahippocampal interleukin-4/interleukin-13 in aged and exercise mice. | |||
|date=20.02.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27916728 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800496 | |||
}} | |||
* {{medline-title | |||
|title=Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4 T cells in aged rats. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448779 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596406 | |||
}} | |||
==SP1== | |||
* {{medline-title | |||
|title=The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation. | |||
|date=09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32717457 | |||
|full-text-url=https://sci-hub.do/10.1016/j.jphotobiol.2020.111964 | |||
}} | |||
* {{medline-title | |||
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. | |||
|date=15.04.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220 | |||
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063 | |||
}} | |||
* {{medline-title | |||
|title=Downregulation of [[CITED2]] contributes to TGFβ-mediated senescence of tendon-derived stem cells. | |||
|date=04.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28084522 | |||
|full-text-url=https://sci-hub.do/10.1007/s00441-016-2552-1 | |||
}} | |||
* {{medline-title | |||
|title=Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase. | |||
|date=01.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25359865 | |||
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.114.303899 | |||
}} | |||
* {{medline-title | |||
|title=A functional and genetic analysis of [[SOD2]] promoter variants and their contribution to age-related hearing loss. | |||
|date=07-08.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23500038 | |||
|full-text-url=https://sci-hub.do/10.1016/j.mad.2013.02.009 | |||
}} | |||
==SSB== | |||
* {{medline-title | |||
|title=Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study. | |||
|date=03.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816850 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950484 | |||
}} | |||
* {{medline-title | |||
|title=WHIRLY1 Occupancy Affects Histone Lysine Modification and [i]WRKY53[/i] Transcription in [i]Arabidopsis[/i] Developmental Manner. | |||
|date=2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30405658 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202938 | |||
}} | |||
* {{medline-title | |||
|title=Modelled health benefits of a sugar-sweetened beverage tax across different socioeconomic groups in Australia: A cost-effectiveness and equity analysis. | |||
|date=06.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28654688 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486958 | |||
}} | |||
* {{medline-title | |||
|title=Reduction of Sugar-Sweetened Beverage Consumption in Elementary School Students Using an Educational Curriculum of Beverage Sugar Content. | |||
|date=2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28620628 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464517 | |||
}} | |||
* {{medline-title | |||
|title=Interannual and Spatial Variability in Maturity of Walleye Pollock Gadus chalcogrammus and Implications for Spawning Stock Biomass Estimates in the Gulf of Alaska. | |||
|date=2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27736982 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063383 | |||
}} | |||
==TBC1D1== | |||
* {{medline-title | |||
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. | |||
|date=02.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688 | |||
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003 | |||
}} | |||
* {{medline-title | |||
|title=Calorie restriction leads to greater Akt2 activity and glucose uptake by insulin-stimulated skeletal muscle from old rats. | |||
|date=01.03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26739650 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796740 | |||
}} | |||
* {{medline-title | |||
|title=Insulin Signaling and Glucose Uptake in the Soleus Muscle of 30-Month-Old Rats After Calorie Restriction With or Without Acute Exercise. | |||
|date=03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26341783 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864161 | |||
}} | |||
* {{medline-title | |||
|title=Effects of sex and age on chicken [[TBC1D1]] gene mRNA expression. | |||
|date=13.07.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26214451 | |||
|full-text-url=https://sci-hub.do/10.4238/2015.July.13.16 | |||
}} | |||
* {{medline-title | |||
|title=AMPK and insulin action--responses to ageing and high fat diet. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23671593 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645997 | |||
}} | |||
==TGFB1== | |||
* {{medline-title | |||
|title=Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. | |||
|date=21.12.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31864349 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925900 | |||
}} | |||
* {{medline-title | |||
|title=[[TGFB1]]-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of [[HOXA5]] and the Age-Dependent Decline in Androgen Receptor Ligands. | |||
|date=26.11.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779094 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928867 | |||
}} | |||
* {{medline-title | |||
|title=Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease. | |||
|date=11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28812215 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665708 | |||
}} | |||
* {{medline-title | |||
|title=Seminal plasma transforming growth factor-β, activin A and follistatin fluctuate within men over time. | |||
|date=10.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27609985 | |||
|full-text-url=https://sci-hub.do/10.1093/humrep/dew185 | |||
}} | |||
* {{medline-title | |||
|title=No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes. | |||
|date=06.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26946122 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841709 | |||
}} | |||
==TLR1== | |||
* {{medline-title | |||
|title=Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. | |||
|date=01.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32969782 | |||
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00615.2020 | |||
}} | |||
* {{medline-title | |||
|title=Association of TLR gene variants in a Czech Red Pied cattle population with reproductive traits. | |||
|date=02.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31901560 | |||
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2019.109997 | |||
}} | |||
* {{medline-title | |||
|title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection. | |||
|date=05.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149 | |||
}} | |||
* {{medline-title | |||
|title=Changes in the expression of the Toll-like receptor system in the aging rat kidneys. | |||
|date=2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24810370 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014502 | |||
}} | |||
* {{medline-title | |||
|title=Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging. | |||
|date=02.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24595889 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969281 | |||
}} | |||
==TLR8== | |||
* {{medline-title | |||
|title=Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. | |||
|date=01.12.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32969782 | |||
|full-text-url=https://sci-hub.do/10.1152/japplphysiol.00615.2020 | |||
}} | |||
* {{medline-title | |||
|title=[[TLR8]]-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy. | |||
|date=08.01.2019 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30344014 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050437 | |||
}} | |||
* {{medline-title | |||
|title=Controlling T cell senescence in the tumor microenvironment for tumor immunotherapy. | |||
|date=03.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25949919 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404789 | |||
}} | |||
* {{medline-title | |||
|title=Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. | |||
|date=06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25834936 | |||
|full-text-url=https://sci-hub.do/10.1016/j.patbio.2015.03.002 | |||
}} | |||
* {{medline-title | |||
|title=[[TLR8]] signaling enhances tumor immunity by preventing tumor-induced T-cell senescence. | |||
|date=10.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25231413 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287933 | |||
}} | |||
==TMPRSS2== | |||
* {{medline-title | |||
|title=[[ACE2]]/[[ADAM17]]/[[TMPRSS2]] Interplay May Be the Main Risk Factor for COVID-19. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117379 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575774 | |||
}} | |||
* {{medline-title | |||
|title=Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 [[ACE2]]-[[TMPRSS2]]-Furin-[[DPP4]] Axis. | |||
|date=2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33013423 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7510459 | |||
}} | |||
* {{medline-title | |||
|title=Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants. | |||
|date=09.09.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32905655 | |||
|full-text-url=https://sci-hub.do/10.1002/jbt.22626 | |||
}} | |||
* {{medline-title | |||
|title=Expression of the SARS-CoV-2 Entry Proteins, [[ACE2]] and [[TMPRSS2]], in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. | |||
|date=03.06.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32379417 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241737 | |||
}} | |||
* {{medline-title | |||
|title=SARS-CoV-2 receptor [[ACE2]] and [[TMPRSS2]] are primarily expressed in bronchial transient secretory cells. | |||
|date=18.05.2020 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32246845 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232010 | |||
}} | |||
==TRH== | |||
* {{medline-title | |||
|title=Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats. | |||
|date=15.03.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29305326 | |||
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2017.12.029 | |||
}} | |||
* {{medline-title | |||
|title=Effect of dietary carbohydrates and time of year on ACTH and cortisol concentrations in adult and aged horses. | |||
|date=04.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195115 | |||
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2017.10.005 | |||
}} | |||
* {{medline-title | |||
|title=The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases. | |||
|date=2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24199031 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817016 | |||
}} | |||
* {{medline-title | |||
|title=Aging-reversing properties of thyrotropin-releasing hormone. | |||
|date=02.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23895526 | |||
|full-text-url=https://sci-hub.do/10.2174/1874609811306010012 | |||
}} | |||
* {{medline-title | |||
|title=Cancer-related fatigue, inflammation and thyrotropin-releasing hormone. | |||
|date=12.2012 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23387883 | |||
|full-text-url=https://sci-hub.do/10.2174/1874609811205030005 | |||
}} | |||
==TRPM8== | |||
* {{medline-title | |||
|title=Morphological and functional changes in [[TRPM8]]-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice. | |||
|date=01.08.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29664111 | |||
|full-text-url=https://sci-hub.do/10.1002/cne.24454 | |||
}} | |||
* {{medline-title | |||
|title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699 | |||
|full-text-url=https://sci-hub.do/10.1111/nmo.13185 | |||
}} | |||
* {{medline-title | |||
|title=Roles of [[TRPM8]] Ion Channels in Cancer: Proliferation, Survival, and Invasion. | |||
|date=23.10.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26512697 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695882 | |||
}} | |||
* {{medline-title | |||
|title=Function and postnatal changes of dural afferent fibers expressing [[TRPM8]] channels. | |||
|date=26.06.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26111800 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480580 | |||
}} | |||
* {{medline-title | |||
|title=Induction of oxidative stress causes functional alterations in mouse urothelium via a [[TRPM8]]-mediated mechanism: implications for aging. | |||
|date=06.2014 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/24593692 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326884 | |||
}} | |||
==VCP== | |||
* {{medline-title | |||
|title=The role of air pollution and lung function in cognitive impairment. | |||
|date=02.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467204 | |||
|full-text-url=https://sci-hub.do/10.1183/13993003.01963-2017 | |||
}} | |||
* {{medline-title | |||
|title=Better parameters of ventilation-CO₂output relationship predict death in CHF patients. | |||
|date=11.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27215018 | |||
}} | |||
* {{medline-title | |||
|title=Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal. | |||
|date=22.03.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27000202 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802725 | |||
}} | |||
* {{medline-title | |||
|title=Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. | |||
|date=24.02.2016 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26912063 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765225 | |||
}} | |||
* {{medline-title | |||
|title=Characterization of C-terminal adaptors, UFD-2 and UFD-3, of CDC-48 on the polyglutamine aggregation in C. elegans. | |||
|date=27.03.2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/25721663 | |||
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2015.02.088 | |||
}} | |||
==WAS== | |||
* {{medline-title | |||
|title=Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number. | |||
|date=09.11.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129830 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723686 | |||
}} | |||
* {{medline-title | |||
|title=Measuring Work Ability with Its Antecedents: Evaluation of the Work Ability Survey. | |||
|date=06.2018 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28741256 | |||
|full-text-url=https://sci-hub.do/10.1007/s10926-017-9720-3 | |||
}} | |||
* {{medline-title | |||
|title=CONSTANCES: a general prospective population-based cohort for occupational and environmental epidemiology: cohort profile. | |||
|date=01.2017 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27884936 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241503 | |||
}} | |||
* {{medline-title | |||
|title=Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice. | |||
|date=2015 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26448644 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598155 | |||
}} | |||
* {{medline-title | |||
|title=Long-term anticoagulation in the extreme elderly with the newer antithrombotics: safe or sorry? | |||
|date=05.2013 | |||
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/23755073 | |||
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675301 | |||
}} | }} |
Текущая версия от 16:42, 29 апреля 2021
- Genes with 300 and more publications
- Genes with 200-299 publications
- Genes with 100-199 publications
- Genes with 90-99 publications
- Genes with 80-89 publications
- Genes with 70-79 publications
- Genes with 60-69 publications
- Genes with 50-59 publications
- Genes with 40-49 publications
- Genes with 30-39 publications
- Genes with 20-29 publications
- Genes with 10-19 publications
- Genes with 5-9 publications
- Genes with 3-4 publications
- Genes with 1-2 publications
- Aging_genes_A-Z_table
ARNT[править]
- Loss of ARNT in skeletal muscle limits muscle regeneration in aging. / 12.2020 / PubMed / Full text
- [Arylhydrocarbon receptor nuclear translocator (ARNT) in human skin during aging.] / 2020 / PubMed
- The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1. / 03.04.2020 / PubMed / Full text
- Deficiency of Bmal1 disrupts the diurnal rhythm of haemostasis. / 04.2019 / PubMed / Full text
- Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling. / 02.11.2018 / PubMed / Full text
- Aging and chromatoid body assembly: Are these two physiological events linked? / 07.2018 / PubMed / Full text
- Deficiency of circadian clock protein BMAL1 in mice results in a low bone mass phenotype. / 03.2016 / PubMed / Full text
- Circadian clocks govern calorie restriction-mediated life span extension through BMAL1- and IGF-1-dependent mechanisms. / 04.2016 / PubMed / Full text
- Whole blood thrombin generation in Bmal1-deficient mice. / 08.2014 / PubMed / Full text
BMP2[править]
- GREM1 inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. / 09.03.2020 / PubMed / Full text
- Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells. / 2020 / PubMed / Full text
- Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging. / 03.12.2018 / PubMed / Full text
- Synthesis of Extracellular Pyrophosphate Increases in Vascular Smooth Muscle Cells During Phosphate-Induced Calcification. / 09.2018 / PubMed / Full text
- Age-Related Insulin-Like Growth Factor Binding Protein-4 Overexpression Inhibits Osteogenic Differentiation of Rat Mesenchymal Stem Cells. / 2017 / PubMed / Full text
- p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner. / 06.04.2017 / PubMed / Full text
- Vaccination with DKK1-derived peptides promotes bone formation and bone mass in an aged mouse osteoporosis model. / 08.2014 / PubMed / Full text
- Enhanced tissue regeneration potential of juvenile articular cartilage. / 11.2013 / PubMed / Full text
- Age-related CXC chemokine receptor-4-deficiency impairs osteogenic differentiation potency of mouse bone marrow mesenchymal stromal stem cells. / 08.2013 / PubMed / Full text
BNIP3[править]
- Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. / 01.10.2019 / PubMed / Full text
- Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training. / 01.10.2018 / PubMed / Full text
- Effects of β-hydroxy-β-methylbutyrate on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults. / 01.11.2017 / PubMed / Full text
- Akt2 ablation prolongs life span and improves myocardial contractile function with adaptive cardiac remodeling: role of Sirt1-mediated autophagy regulation. / 10.2017 / PubMed / Full text
- In Brief: Mitophagy: mechanisms and role in human disease. / 11.2016 / PubMed / Full text
- Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway. / 01.08.2016 / PubMed / Full text
- Interfacing mitochondrial biogenesis and elimination to enhance host pathogen defense and longevity. / 07-09.2015 / PubMed / Full text
- Coupling mitogenesis and mitophagy for longevity. / 2015 / PubMed / Full text
- Dying myofibers in elderly mouse skeletal muscles are characterized by the appearance of dystrophin-encircled vacuoles. / 08.2015 / PubMed / Full text
BPIFB4[править]
- New Insights for BPIFB4 in Cardiovascular Therapy. / 28.09.2020 / PubMed / Full text
- High TARC plasma levels confer protection to long living individuals by inducing M2 profile. / 01.2021 / PubMed / Full text
- Circulating BPIFB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals. / 2020 / PubMed / Full text
- Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway. / 09.2020 / PubMed / Full text
- LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice. / 28.08.2019 / PubMed / Full text
- Longevity-Associated Variant of BPIFB4 Mitigates Monocyte-Mediated Acquired Immune Response. / 13.11.2019 / PubMed / Full text
- A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of BPIFB4. / 19.10.2018 / PubMed / Full text
- The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy. / 22.01.2017 / PubMed / Full text
- Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis. / 31.07.2015 / PubMed / Full text
CCN1[править]
- Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis. / 09.2020 / PubMed / Full text
- Inhibition of cellular communication network factor 1 (CCN1)-driven senescence slows down cartilage inflammaging and osteoarthritis. / 10.2020 / PubMed / Full text
- [Aging of skin fibroblasts: genetic and epigenetic factors.] / 2019 / PubMed
- The senescence-associated matricellular protein CCN1 in plasma of human subjects with idiopathic pulmonary fibrosis. / 01.2020 / PubMed / Full text
- CCN1 (CYR61) and CCN3 (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties. / 03.03.2016 / PubMed / Full text
- Aging increases CCN1 expression leading to muscle senescence. / 01.01.2014 / PubMed / Full text
- Impaired intervertebral disc development and premature disc degeneration in mice with notochord-specific deletion of CCN2. / 10.2013 / PubMed / Full text
- The matricellular protein CCN1 suppresses lung cancer cell growth by inducing senescence via the p53/p21 pathway. / 09.2013 / PubMed / Full text
- Cysteine-rich protein 61 (CCN1) domain-specific stimulation of matrix metalloproteinase-1 expression through αVβ3 integrin in human skin fibroblasts. / 26.04.2013 / PubMed / Full text
CCR5[править]
- The Puzzling Role of Neuron-Specific PMCA Isoforms in the Aging Process. / 16.12.2019 / PubMed / Full text
- [Enhancement can do harm]. / 08-09.2019 / PubMed / Full text
- CCR5-∆32 is deleterious in the homozygous state in humans. / 06.2019 / PubMed / Full text
- CCR5 chemokine receptor gene polymorphisms in ocular toxoplasmosis. / 02.2018 / PubMed / Full text
- Peripheral loss of CD8( ) CD161( ) TCRVα7·2( ) mucosal-associated invariant T cells in chronic hepatitis C virus-infected patients. / 02.2016 / PubMed / Full text
- Increased susceptibility of CD4 T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels. / 09.10.2015 / PubMed / Full text
- Aging-associated subpopulations of human CD8 T-lymphocytes identified by their CD28 and CD57 phenotypes. / 11-12.2015 / PubMed / Full text
- Cutting edge: Central memory CD8 T cells in aged mice are virtual memory cells. / 15.12.2013 / PubMed / Full text
- [[[CCR5]], CCR2, apoe, p53, ITGB3 and HFE gene polymorphism in Western Siberia long-livers]. / 2012 / PubMed
CDA[править]
- Cumulative Dis/Advantage and Health Pattern in Late Life: A Comparison between Genders and Welfare State Regimes. / 2019 / PubMed / Full text
- Does numerical similarity alter age-related distractibility in working memory? / 2019 / PubMed / Full text
- Can working memory capacity be expanded by boosting working memory updating efficiency in older adults? / 12.2018 / PubMed / Full text
- Negative Affect Influences Electrophysiological Markers of Visual Working Memory in Mildly Stressed Older Adults. / 2018 / PubMed / Full text
- EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development. / 02.2018 / PubMed / Full text
- Mini dental assessment: a simple screening test for non-dental staff. / 06.2017 / PubMed / Full text
- Electrophysiological Correlates of Subitizing in Healthy Aging. / 2015 / PubMed / Full text
- Understanding age-related reductions in visual working memory capacity: examining the stages of change detection. / 10.2014 / PubMed / Full text
- Retrospective attention enhances visual working memory in the young but not the old: an ERP study. / 05.2013 / PubMed / Full text
CTCF[править]
- New targeted approaches for epigenetic age predictions. / 24.06.2020 / PubMed / Full text
- Blood DNA Methylation and Aging: A Cross-Sectional Analysis and Longitudinal Validation in the InCHIANTI Study. / 15.10.2020 / PubMed / Full text
- In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text
- Genetic Insights Into Frailty: Association of 9p21-23 Locus With Frailty. / 2018 / PubMed / Full text
- HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types. / 17.05.2018 / PubMed / Full text
- Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes. / 2015 / PubMed / Full text
- Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape. / 2013 / PubMed / Full text
- Chromatin remodeling of human subtelomeres and TERRA promoters upon cellular senescence: commonalities and differences between chromosomes. / 05.2013 / PubMed / Full text
- Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. / 07.2013 / PubMed / Full text
CXCL2[править]
- Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. / 2020 / PubMed / Full text
- Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression. / 2019 / PubMed / Full text
- Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice. / 02.05.2019 / PubMed / Full text
- A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. / 19.02.2019 / PubMed / Full text
- Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality. / 03.2019 / PubMed / Full text
- Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles. / 05.2018 / PubMed / Full text
- Tumor microenvironment in functional adrenocortical adenomas: immune cell infiltration in cortisol-producing adrenocortical adenoma. / 07.2018 / PubMed / Full text
- Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. / 02.2017 / PubMed / Full text
- Mice with heterozygous deficiency of manganese superoxide dismutase (SOD2) have a skin immune system with features of "inflamm-aging". / 03.2014 / PubMed / Full text
DBI[править]
- Quantifying cumulative anticholinergic and sedative drug load among US Medicare Beneficiaries. / 01.10.2020 / PubMed / Full text
- Drug Burden Index and Cognitive and Physical Function in Aged Care Residents: A Longitudinal Study. / 08.2020 / PubMed / Full text
- Using the Drug Burden Index to identify older adults at highest risk for medication-related falls. / 12.06.2020 / PubMed / Full text
- Impact of STEADI-Rx: A Community Pharmacy-Based Fall Prevention Intervention. / 08.2020 / PubMed / Full text
- Association of Drug Burden Index with grip strength, timed up and go and Barthel index activities of daily living in older adults with intellectual disabilities: an observational cross-sectional study. / 24.06.2019 / PubMed / Full text
- Impact of drug burden index on adverse health outcomes in Irish community-dwelling older people: a cohort study. / 29.04.2019 / PubMed / Full text
- Dietary Balance Index-07 and the Risk of Anemia in Middle Aged and Elderly People in Southwest China: A Cross Sectional Study. / 31.01.2018 / PubMed / Full text
- Effects of Changes in Number of Medications and Drug Burden Index Exposure on Transitions Between Frailty States and Death: The Concord Health and Ageing in Men Project Cohort Study. / 01.2016 / PubMed / Full text
- Drug Burden Index score and anticholinergic risk scale as predictors of readmission to the hospital. / 03.2014 / PubMed / Full text
DES[править]
- Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis. / 20.03.2018 / PubMed / Full text
- Genetic variation in low-dose effects of neonatal DES exposure in female rats. / 10.2017 / PubMed / Full text
- Aging Eye Microbiota in Dry Eye Syndrome in Patients Treated with [i]Enterococcus faecium[/i] and [i]Saccharomyces boulardii[/i]. / 2017 / PubMed / Full text
- The influence of advancing age on implantation of drug-eluting stents. / 10.2016 / PubMed / Full text
- Calculating when elective abdominal aortic aneurysm repair improves survival for individual patients: development of the Aneurysm Repair Decision Aid and economic evaluation. / 04.2015 / PubMed / Full text
- Diethylstilbestrol exposure in neonatal mice induces changes in the adulthood in the immune response to taenia crassiceps without modifications of parasite loads. / 2014 / PubMed / Full text
- Androgen deficiency and dry eye syndrome in the aging male. / 03.07.2014 / PubMed / Full text
- [[[DES]] Daughter--expertise remains necessary]. / 2013 / PubMed
- Emotional reactivity assessment of healthy elderly with an emotion-induction procedure. / 2013 / PubMed / Full text
EDA[править]
- Interplay between aging, lung inflammation/remodeling, and fibronectin EDA in lung cancer progression. / 01.12.2020 / PubMed / Full text
- Arousal Detection in Elderly People from Electrodermal Activity Using Musical Stimuli. / 25.08.2020 / PubMed / Full text
- The structure of agricultural microplastics (PT, PU and UF) and their sorption capacities for PAHs and PHE derivates under various salinity and oxidation treatments. / 02.2020 / PubMed / Full text
- Effect of storage on quality parameters and phenolic content of Italian extra-virgin olive oils. / 01.2020 / PubMed / Full text
- Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice. / 03.2018 / PubMed / Full text
- An Extract from the Plant [i]Deschampsia antarctica[/i] Protects Fibroblasts from Senescence Induced by Hydrogen Peroxide. / 2017 / PubMed / Full text
- Occurrence of fibronectin-fibrin complexes in plasma of patients with multimorbidity due to the inflamm-aging phenomenon. / 05.2016 / PubMed / Full text
- Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy. / 09.2015 / PubMed / Full text
- Error detection and error memory in spatial navigation as reflected by electrodermal activity. / 11.2013 / PubMed / Full text
FOXM1[править]
- Sirtuin 6 deficiency induces endothelial cell senescence via downregulation of forkhead box M1 expression. / 10.11.2020 / PubMed / Full text
- Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma. / 21.11.2018 / PubMed / Full text
- Preclinical characterization of abemaciclib in hormone receptor positive breast cancer. / 19.09.2017 / PubMed / Full text
- Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. / 02.10.2017 / PubMed / Full text
- FOXM1 regulates proliferation, senescence and oxidative stress in keratinocytes and cancer cells. / 07.2016 / PubMed / Full text
- MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells. / 02.10.2015 / PubMed / Full text
- Increased FOXM1 expression can stimulate DNA repair in normal hepatocytes in vivo but also increases nuclear foci associated with senescence. / 02.2015 / PubMed / Full text
- Cellular senescence and aging: the role of B-MYB. / 10.2014 / PubMed / Full text
- MiR-506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer. / 07.2014 / PubMed / Full text
GAA[править]
- Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia. / 27.07.2020 / PubMed / Full text
- Age-Related Changes in Serum Guanidinoacetic Acid in Women. / 30.12.2019 / PubMed / Full text
- ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
- Age and gender-specific reference intervals for lysosomal enzymes in dried blood spot samples: A study in Indian population. / 10.2017 / PubMed / Full text
- Effects of guanidinoacetic acid diet supplementation on semen quality and fertility of broiler breeder roosters. / 02.2017 / PubMed / Full text
- Effect of feeding guanidinoacetic acid and L-arginine on the fertility rate and sperm penetration in the perivitelline layer of aged broiler breeder hens. / 04.2016 / PubMed / Full text
- Combined aerobic exercise and enzyme replacement therapy rejuvenates the mitochondrial-lysosomal axis and alleviates autophagic blockage in Pompe disease. / 10.2015 / PubMed / Full text
- Dietary guanidino acetic acid is an efficacious replacement for arginine for young chicks. / 01.2013 / PubMed / Full text
GK[править]
- Progression of diabetic kidney disease in T2DN rats. / 01.12.2019 / PubMed / Full text
- Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging. / 04.2019 / PubMed / Full text
- Age-Related Reduction of Contractile Responses to Urotensin II Is Seen in Aortas from Wistar Rats but Not from Type 2 Diabetic Goto-Kakizaki Rats. / 04.2017 / PubMed / Full text
- [STUDY RELATIVE EXPRESSION OF GENES THAT CONTROL GLUCOSE METABOLISM IN THE LIVER IN MICE WITH DEVELOPMENT OF MELANOCORTIN OBESITY]. / 06.2015 / PubMed
- Delta Cell Hyperplasia in Adult Goto-Kakizaki (GK/MolTac) Diabetic Rats. / 2015 / PubMed / Full text
- Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes. / 2014 / PubMed / Full text
- Evidence for cortical neuronal loss in male type 2 diabetic Goto-Kakizaki rats. / 2014 / PubMed / Full text
- Dietary resistant starch improves selected brain and behavioral functions in adult and aged rodents. / 11.2013 / PubMed / Full text
- Decreased glucokinase protein expression in the aged gerbil hippocampus. / 05.2013 / PubMed / Full text
HDAC2[править]
- EEF1A1 deacetylation enables transcriptional activation of remyelination. / 09.07.2020 / PubMed / Full text
- Endothelial toll-like receptor 4 maintains lung integrity via epigenetic suppression of p16 . / 06.2019 / PubMed / Full text
- Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke. / 04.2019 / PubMed / Full text
- HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State. / 04.12.2018 / PubMed / Full text
- Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS. / 10.2018 / PubMed / Full text
- Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri. / 09.2018 / PubMed / Full text
- Histone Deacetylase 2 Inhibition Attenuates Downregulation of Hippocampal Plasticity Gene Expression during Aging. / 03.2018 / PubMed / Full text
- Non-sirtuin histone deacetylases in the control of cardiac aging. / 06.2015 / PubMed / Full text
- Histone deacetylase 2 in the mouse hippocampus: attenuation of age-related increase by caloric restriction. / 10.2013 / PubMed / Full text
IDH2[править]
- Oxidative Damage to the TCA Cycle Enzyme MDH1 Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. / 03.04.2020 / PubMed / Full text
- Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions. / 10.09.2019 / PubMed / Full text
- Augmentation of cellular NAD by NQO1 enzymatic action improves age-related hearing impairment. / 10.2019 / PubMed / Full text
- Improving Treatment for Myelodysplastic Syndromes Patients. / 25.10.2018 / PubMed / Full text
- Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice. / 22.03.2018 / PubMed / Full text
- IDH2-deficient mice develop spinal deformities with aging. / 17.07.2018 / PubMed / Full text
- Idh2 deficiency accelerates renal dysfunction in aged mice. / 04.11.2017 / PubMed / Full text
- IDH1 Associated with Neuronal Apoptosis in Adult Rats Brain Following Intracerebral Hemorrhage. / 07.2017 / PubMed / Full text
- Epigenetic Aging Signatures Are Coherently Modified in Cancer. / 06.2015 / PubMed / Full text
IDS[править]
- Effect of immediate dentine sealing on the aging and fracture strength of lithium disilicate inlays and overlays. / 10.2020 / PubMed / Full text
- Increased double limb support times during walking in right limb dominant healthy older adults with low bone density. / 06.2018 / PubMed / Full text
- Comparison of two automated assays of BTM (CTX and P1NP) and reference intervals in a Danish population. / 07.2017 / PubMed / Full text
- Metabolic dysregulation and late-life depression: a prospective study. / 04.2017 / PubMed / Full text
- Total tooth loss and complete denture use in older adults with intellectual disabilities in Ireland. / Spring.2015 / PubMed / Full text
- Depression in later life: a more somatic presentation? / 01.01.2015 / PubMed / Full text
- Reference intervals for insulin-like growth factor-1 (igf-i) from birth to senescence: results from a multicenter study using a new automated chemiluminescence IGF-I immunoassay conforming to recent international recommendations. / 05.2014 / PubMed / Full text
- Age- and sex-specific reference intervals across life span for insulin-like growth factor binding protein 3 (IGFBP-3) and the IGF-I to IGFBP-3 ratio measured by new automated chemiluminescence assays. / 05.2014 / PubMed / Full text
- Transcriptomics of cortical gray matter thickness decline during normal aging. / 15.11.2013 / PubMed / Full text
ILK[править]
- Concurrent nicotine exposure to prenatal alcohol consumption alters the hippocampal and cortical neurotoxicity. / 01.2020 / PubMed / Full text
- Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy. / 01.04.2019 / PubMed / Full text
- Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia. / 10.2018 / PubMed / Full text
- Integrin-linked kinase: A new actor in the ageing process? / 15.12.2017 / PubMed / Full text
- Hyperphosphatemia induces cellular senescence in human aorta smooth muscle cells through integrin linked kinase (ILK) up-regulation. / 12.2015 / PubMed / Full text
- Integrin-linked kinase regulates senescence in an Rb-dependent manner in cancer cell lines. / 2015 / PubMed / Full text
- A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. / 06.2014 / PubMed / Full text
- Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1. / 06.2014 / PubMed / Full text
- PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling. / 13.11.2014 / PubMed / Full text
LAMP1[править]
- Resemblance and differences in dietary restriction nephroprotective mechanisms in young and old rats. / 24.09.2020 / PubMed / Full text
- An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into RPE Stress Associated with Retinopathy. / 11.09.2020 / PubMed / Full text
- Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain. / 24.06.2020 / PubMed / Full text
- Yishen Huazhuo Decoction Induces Autophagy to Promote the Clearance of Aβ1-42 in SAMP8 Mice: Mechanism Research of a Traditional Chinese Formula Against Alzheimer's Disease. / 2020 / PubMed / Full text
- Dysregulations of mitochondrial quality control and autophagic flux at an early age lead to progression of sarcopenia in SAMP8 mice. / 06.2020 / PubMed / Full text
- Deacetylation of LAMP1 drives lipophagy-dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer. / 03.2020 / PubMed / Full text
- A pH probe inhibits senescence in mesenchymal stem cells. / 07.12.2018 / PubMed / Full text
- Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. / 01.10.2017 / PubMed / Full text
- Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease). / 15.12.2015 / PubMed / Full text
LSS[править]
- Surgical results in older patients with lumbar spinal stenosis according to gait speed in relation to the diagnosis for sarcopenia. / 01-04.2020 / PubMed / Full text
- Streamlining an existing hip fracture patient pathway in an acute tertiary adult Irish hospital to improve patient experience and outcomes. / 22.12.2019 / PubMed / Full text
- Low-dose radiation from A-bombs elongated lifespan and reduced cancer mortality relative to un-irradiated individuals. / 2018 / PubMed / Full text
- Lung, Laryngeal and Other Respiratory Cancer Incidence among Japanese Atomic Bomb Survivors: An Updated Analysis from 1958 through 2009. / 05.2017 / PubMed / Full text
- Quantitating the lateral skin stiffness by a new and versatile electro-mechanical instrument. Preliminary studies. / 08.2017 / PubMed / Full text
- A message to Fukushima: nothing to fear but fear itself. / 2016 / PubMed / Full text
- Exposure to ionizing radiation and brain cancer incidence: The Life Span Study cohort. / 06.2016 / PubMed / Full text
- Lumbar spondylosis, lumbar spinal stenosis, knee pain, back muscle strength are associated with the locomotive syndrome: Rural population study in Japan. / 05.2016 / PubMed / Full text
- Does Obesity Affect Outcomes After Decompressive Surgery for Lumbar Spinal Stenosis? A Multicenter, Observational, Registry-Based Study. / 11.2015 / PubMed / Full text
MFI[править]
- The Influence of the Accelerated Aging Conditions on the Properties of Polyolefin Geogrids Used for Landfill Slope Reinforcement. / 20.08.2020 / PubMed / Full text
- Changes in Physical Meat Traits, Protein Solubility, and the Microstructure of Different Beef Muscles during Post-Mortem Aging. / 19.06.2020 / PubMed / Full text
- Effect of a low-voltage electrical stimulation on yak meat tenderness during postmortem aging. / 01-12.2020 / PubMed / Full text
- Comparative effects of dry-aging and wet-aging on physicochemical properties and digestibility of Hanwoo beef. / 03.2020 / PubMed / Full text
- Sexual dimorphism in rat thymic involution: a correlation with thymic oxidative status and inflammation. / 08.2019 / PubMed / Full text
- Circulating soluble RAGE and cell surface RAGE on peripheral blood mononuclear cells in healthy children. / 27.06.2018 / PubMed / Full text
- The frail fail: Increased mortality and post-operative complications in orthopaedic trauma patients. / 11.2017 / PubMed / Full text
- Meat quality attributes of Agile Wallabies. / 11.2017 / PubMed / Full text
- Phagocyte dysfunction in polymyalgia rheumatica and other age-related, chronic, inflammatory conditions. / 11.2013 / PubMed / Full text
MIA[править]
- TP53/miR-34a-associated signaling targets [i]SERPINE1[/i] expression in human pancreatic cancer. / 27.01.2020 / PubMed / Full text
- Age, cohort, and period effects on metamemory beliefs. / 12.2019 / PubMed / Full text
- Memory Age-based Stereotype Threat: Role of Locus of Control and Anxiety. / 01-02.2020 / PubMed / Full text
- Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice. / 27.09.2019 / PubMed / Full text
- Role of melanoma inhibitory activity in melanocyte senescence. / 11.2019 / PubMed / Full text
- Refining the metamemory in adulthood questionnaire: a 20-item version of change and capacity designed for research and clinical settings. / 07.2020 / PubMed / Full text
- Maternal Immune Activation Alters Adult Behavior, Gut Microbiome and Juvenile Brain Oscillations in Ferrets. / 09-10.2018 / PubMed / Full text
- Differential proteomic and oxidative profiles unveil dysfunctional protein import to adipocyte mitochondria in obesity-associated aging and diabetes. / 04.2017 / PubMed / Full text
- Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice. / 06.2015 / PubMed / Full text
MMD[править]
- Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study. / 22.11.2020 / PubMed / Full text
- Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study. / 16.09.2020 / PubMed / Full text
- Impact and Lessons From the Lifestyle Interventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability. / 04.2020 / PubMed / Full text
- Lactobacillus rescues postnatal neurobehavioral and microglial dysfunction in a model of maternal microbiome dysbiosis. / 10.2019 / PubMed / Full text
- A Case for Promoting Movement Medicine: Preventing Disability in the LIFE Randomized Controlled Trial. / 04.10.2019 / PubMed / Full text
- Determinants of Basal Collaterals in Moyamoya Disease: Clinical and Genetic Factors. / 2016 / PubMed / Full text
- Antihypertensive Use and the Effect of a Physical Activity Intervention in the Prevention of Major Mobility Disability Among Older Adults: The LIFE Study. / 07.2016 / PubMed / Full text
- Perfusion characteristics of Moyamoya disease: an anatomically and clinically oriented analysis and comparison. / 01.2014 / PubMed / Full text
- Do older patients find multi-compartment medication devices easy to use and which are the easiest? / 11.2013 / PubMed / Full text
MRE11[править]
- TPP1 Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the MRE11/AKT Pathway. / 2020 / PubMed / Full text
- Chromosomal alterations among age-related haematopoietic clones in Japan. / 08.2020 / PubMed / Full text
- ATM Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy. / 2019 / PubMed / Full text
- Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. / 2019 / PubMed / Full text
- The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. / 2018 / PubMed / Full text
- Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells. / 01.09.2018 / PubMed / Full text
- BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries. / 03.04.2017 / PubMed / Full text
- NBS1 is required for macrophage homeostasis and functional activity in mice. / 26.11.2015 / PubMed / Full text
- Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans. / 13.02.2013 / PubMed / Full text
MSTN[править]
- Age- and stage-dependent variations of muscle-specific gene expression in brown trout Salmo trutta L. / 09.2017 / PubMed / Full text
- Activity of metabolic enzymes and muscle-specific gene expression in parr and smolts Atlantic salmon Salmo salar L. of different age groups. / 08.2017 / PubMed / Full text
- miR-30e is negatively regulated by myostatin in skeletal muscle and is functionally related to fiber-type composition. / 01.05.2017 / PubMed / Full text
- Muscle-Related Polymorphisms (MSTN rs1805086 and ACTN3 rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians. / 2016 / PubMed / Full text
- Temporal and spatial expression of Smads and their correlation with YAP1 expression in sheep. / 26.08.2016 / PubMed / Full text
- Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease. / 14.06.2016 / PubMed / Full text
- Morphological analysis and muscle-associated gene expression during different muscle growth phases of Megalobrama amblycephala. / 28.09.2015 / PubMed / Full text
- The effect of exercise mode on the acute response of satellite cells in old men. / 12.2015 / PubMed / Full text
- Association of the K153R polymorphism in the myostatin gene and extreme longevity. / 12.2013 / PubMed / Full text
PNN[править]
- Hyaluronan degradation and release of a hyaluronan-aggrecan complex from perineuronal nets in the aged mouse brain. / 28.11.2020 / PubMed / Full text
- Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory. / 29.10.2019 / PubMed / Full text
- Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex. / 09.2019 / PubMed / Full text
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
- Age-dependent and region-specific alteration of parvalbumin neurons and perineuronal nets in the mouse cerebral cortex. / 01.2018 / PubMed / Full text
- Brain ageing changes proteoglycan sulfation, rendering perineuronal nets more inhibitory. / 28.06.2017 / PubMed / Full text
- Removal of Perineuronal Nets Unlocks Juvenile Plasticity Through Network Mechanisms of Decreased Inhibition and Increased Gamma Activity. / 01.02.2017 / PubMed / Full text
- Age-Related Deterioration of Perineuronal Nets in the Primary Auditory Cortex of Mice. / 2016 / PubMed / Full text
- Spatio-temporal differences in perineuronal net expression in the mouse hippocampus, with reference to parvalbumin. / 03.12.2013 / PubMed / Full text
POLG[править]
- Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. / 08.07.2019 / PubMed / Full text
- Parkin does not prevent accelerated cardiac aging in mitochondrial DNA mutator mice. / 16.04.2019 / PubMed / Full text
- The effects of AICAR and rapamycin on mitochondrial function in immortalized mitochondrial DNA mutator murine embryonic fibroblasts. / 16.11.2018 / PubMed / Full text
- Impact of exercise on oocyte quality in the POLG mitochondrial DNA mutator mouse. / 08.2018 / PubMed / Full text
- The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways. / 08.2017 / PubMed / Full text
- Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain. / 11.2015 / PubMed / Full text
- Mitochondria DNA mutations cause sex-dependent development of hypertension and alterations in cardiovascular function. / 05.02.2015 / PubMed / Full text
- Somatic mitochondrial DNA mutations do not increase neuronal vulnerability to MPTP in young POLG mutator mice. / 11-12.2014 / PubMed / Full text
- The impact of pathogenic mitochondrial DNA mutations on substantia nigra neurons. / 26.06.2013 / PubMed / Full text
RAD51[править]
- 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. / 02.01.2020 / PubMed / Full text
- Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. / 09.07.2019 / PubMed / Full text
- Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae. / 01.08.2019 / PubMed / Full text
- Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. / 2019 / PubMed / Full text
- The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. / 2018 / PubMed / Full text
- Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence. / 11.10.2016 / PubMed / Full text
- BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries. / 03.04.2017 / PubMed / Full text
- SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. / 02.10.2016 / PubMed / Full text
- RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins. / 01.2016 / PubMed / Full text
SMAD2[править]
- Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging. / 18.11.2020 / PubMed / Full text
- The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation. / 09.2020 / PubMed / Full text
- Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation. / 02.2020 / PubMed / Full text
- Restoring extracellular matrix synthesis in senescent stem cells. / 10.2019 / PubMed / Full text
- iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation. / 01.10.2017 / PubMed / Full text
- Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting. / 07.2017 / PubMed / Full text
- Circulating Growth Differentiation Factor 11/8 Levels Decline With Age. / 08.01.2016 / PubMed / Full text
- Effects of aging on cardiac extracellular matrix in men and women. / 01.2016 / PubMed / Full text
- Age-associated changes in gene expression of goat oocytes. / 01.09.2013 / PubMed / Full text
SON[править]
- Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha. / 01.10.2019 / PubMed / Full text
- Neural Mechanisms Involved in the Noxious Physical Stress-Induced Inhibition of Ovarian Estradiol Secretion. / 06.2019 / PubMed / Full text
- Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. / 01.08.2018 / PubMed / Full text
- The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system. / 05.2018 / PubMed / Full text
- Increased oxytocin-monomeric red fluorescent protein 1 fluorescent intensity with urocortin-like immunoreactivity in the hypothalamo-neurohypophysial system of aged transgenic rats. / 03.2018 / PubMed / Full text
- Age-Related (Aged vs. Adult) Comparison of the Effect of Two Mild Stressors on the Nerve Growth Factor (NGF) in the Rat Hypothalamic Supraoptic Nucleus (SON) - Immunohistochemical Study. / 2016 / PubMed
- Exposure to mild stress and brain derived neurotrophin factor (BDNF) immunoreactivity in the hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei: Comparison between aged and adult rats. / 12.2016 / PubMed / Full text
- Testing the critical window of estradiol replacement on gene expression of vasopressin, oxytocin, and their receptors, in the hypothalamus of aging female rats. / 05.01.2016 / PubMed / Full text
- [Lamellar complex changes in the human basal forebrain and hypothalamic nuclei neurons in different age groups]. / 2014 / PubMed
SQSTM1[править]
- The selective autophagy receptor SQSTM1/p62 improves lifespan and proteostasis in an evolutionarily conserved manner. / 04.2020 / PubMed / Full text
- SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence. / 06.2020 / PubMed / Full text
- SIRT2 functions in aging, autophagy, and apoptosis in post-maturation bovine oocytes. / 01.09.2019 / PubMed / Full text
- A pH probe inhibits senescence in mesenchymal stem cells. / 07.12.2018 / PubMed / Full text
- The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. / 04.2019 / PubMed / Full text
- Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1 -expressing ALS mouse model. / 29.05.2018 / PubMed / Full text
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
- SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. / 02.10.2016 / PubMed / Full text
- Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. / 02.11.2015 / PubMed / Full text
VHL[править]
- Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a VHL-1-independent transcriptional response. / 12.2020 / PubMed / Full text
- The Energy Maintenance Theory of Aging: Maintaining Energy Metabolism to Allow Longevity. / 08.2018 / PubMed / Full text
- Shorter telomere length increases age-related tumor risks in von Hippel-Lindau disease patients. / 09.2017 / PubMed / Full text
- Biological and clinical impact of hemangioblastoma-associated peritumoral cysts in von Hippel-Lindau disease. / 04.2016 / PubMed / Full text
- Long-term prognosis of patients with pediatric pheochromocytoma. / 02.2014 / PubMed / Full text
- Inactivation of Vhl in osteochondral progenitor cells causes high bone mass phenotype and protects against age-related bone loss in adult mice. / 04.2014 / PubMed / Full text
- Senescence-associated protein p400 is a prognostic marker in renal cell carcinoma. / 11.2013 / PubMed / Full text
- E2F1 in renal cancer: Mr Hyde disguised as Dr Jekyll? / 10.2013 / PubMed / Full text
- Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner. / 08.2013 / PubMed / Full text
VWF[править]
- Von Willebrand disease in the elderly: clinical perspectives. / 2018 / PubMed / Full text
- Comorbidities associated with higher von Willebrand factor (VWF) levels may explain the age-related increase of VWF in von Willebrand disease. / 07.2018 / PubMed / Full text
- The Association of Aging With Von Willebrand Factor Levels and Bleeding Risk in Type 1 Von Willebrand Disease. / 04.2018 / PubMed / Full text
- Aging and ABO blood type influence von Willebrand factor and factor VIII levels through interrelated mechanisms. / 05.2016 / PubMed / Full text
- Age-related changes in platelet function are more profound in women than in men. / 16.07.2015 / PubMed / Full text
- Von Willebrand factor and aging. / 09.2014 / PubMed / Full text
- Aging hemostasis: changes to laboratory markers of hemostasis as we age - a narrative review. / 09.2014 / PubMed / Full text
- von Willebrand disease and aging: an evolving phenotype. / 07.2014 / PubMed / Full text
- Age-related changes in aortic valve hemostatic protein regulation. / 01.2014 / PubMed / Full text
XIAP[править]
- Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and XIAP. / 01.10.2019 / PubMed / Full text
- Modulated electro-hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro. / 08.2019 / PubMed / Full text
- Protective effect of xanthohumol against age-related brain damage. / 11.2017 / PubMed / Full text
- Molecular modeling in the age of clinical genomics, the enterprise of the next generation. / 03.2017 / PubMed / Full text
- Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. / 10.2016 / PubMed / Full text
- XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence. / 02.02.2016 / PubMed / Full text
- Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells. / 2015 / PubMed / Full text
- Increase in retinal ganglion cells' susceptibility to elevated intraocular pressure and impairment of their endogenous neuroprotective mechanism by age. / 2013 / PubMed / Full text
- The member of high temperature requirement family HtrA2 participates in neuronal apoptosis after intracerebral hemorrhage in adult rats. / 08.2013 / PubMed / Full text
YAP1[править]
- Loss of Wasl improves pancreatic cancer outcome. / 21.05.2020 / PubMed / Full text
- Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. / 13.01.2020 / PubMed / Full text
- Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1. / 05.09.2019 / PubMed / Full text
- [Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. / 25.06.2019 / PubMed
- YAP1-LATS2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis. / 03.2019 / PubMed / Full text
- Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text
- Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2. / 01.2017 / PubMed / Full text
- Temporal and spatial expression of Smads and their correlation with YAP1 expression in sheep. / 26.08.2016 / PubMed / Full text
- Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. / 29.09.2015 / PubMed / Full text
ABCA1[править]
- Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension. / 01.07.2019 / PubMed / Full text
- Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. / 08.2018 / PubMed / Full text
- Advanced glycation end products affect cholesterol homeostasis by impairing ABCA1 expression on macrophages. / 08.2017 / PubMed / Full text
- Genome-wide DNA methylation profiles reveal novel candidate genes associated with meat quality at different age stages in hens. / 05.04.2017 / PubMed / Full text
- Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice. / 15.01.2016 / PubMed / Full text
- Dynamic changes of Apo A1 mediated by LXR/RXR/ABCA1 pathway in brains of the aging rats with cerebral hypoperfusion. / 01.2014 / PubMed / Full text
- Elevated COX2 expression and PGE2 production by downregulation of RXRα in senescent macrophages. / 11.10.2013 / PubMed / Full text
- Genetic determinants of macular pigments in women of the Carotenoids in Age-Related Eye Disease Study. / 28.03.2013 / PubMed / Full text
ACTN3[править]
- Altered miRNA and mRNA Expression in Sika Deer Skeletal Muscle with Age. / 06.02.2020 / PubMed / Full text
- The Role of Genetic Profile in Functional Performance Adaptations to Exercise Training or Physical Activity: A Systematic Review of the Literature. / 01.08.2019 / PubMed / Full text
- Is evolutionary loss our gain? The role of ACTN3 p.Arg577Ter (R577X) genotype in athletic performance, ageing, and disease. / 12.2018 / PubMed / Full text
- ACTN3 genotype and physical function and frailty in an elderly Chinese population: the Rugao Longevity and Ageing Study. / 01.05.2018 / PubMed / Full text
- Muscle-Related Polymorphisms (MSTN rs1805086 and ACTN3 rs1815739) Are Not Associated with Exceptional Longevity in Japanese Centenarians. / 2016 / PubMed / Full text
- Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing. / 09.2016 / PubMed / Full text
- The ACTN3 R577X genotype is associated with muscle function in a Japanese population. / 04.2015 / PubMed / Full text
- 1000 Norms Project: protocol of a cross-sectional study cataloging human variation. / 03.2016 / PubMed / Full text
ASXL1[править]
- Aging and leukemic evolution of hematopoietic stem cells under various stress conditions. / 05.11.2020 / PubMed / Full text
- 60 Years of clonal hematopoiesis research: From X-chromosome inactivation studies to the identification of driver mutations. / 03.2020 / PubMed / Full text
- ASXL1 mutation in clonal hematopoiesis. / 03.2020 / PubMed / Full text
- Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease. / 03.2020 / PubMed / Full text
- [Role of ASXL1 mutations in hematological disorders]. / 2019 / PubMed / Full text
- Clonal hematopoiesis: Genes and underlying mechanisms in cardiovascular disease development. / 06.2019 / PubMed / Full text
- A primer for epigenetics of hematological malignancies. / 2016 / PubMed / Full text
- The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. / 27.11.2015 / PubMed / Full text
B2M[править]
- Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy. / 22.09.2020 / PubMed / Full text
- The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. / 03.2019 / PubMed / Full text
- Association between serum β2-microglobulin levels and frailty in an elderly Chinese population: results from RuLAS. / 2017 / PubMed / Full text
- Non-GFR Determinants of Low-Molecular-Weight Serum Protein Filtration Markers in the Elderly: AGES-Kidney and MESA-Kidney. / 09.2017 / PubMed / Full text
- Association Between Serum β -Microglobulin Levels and Prevalent and Incident Physical Frailty in Community-Dwelling Older Women. / 04.2017 / PubMed / Full text
- A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood. / 22.11.2016 / PubMed / Full text
- β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis. / 08.2015 / PubMed / Full text
- Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal. / 20.05.2015 / PubMed / Full text
BIN1[править]
- Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice. / 20.03.2019 / PubMed / Full text
- Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text
- Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
- Dopamine Receptor Genes Modulate Associative Memory in Old Age. / 02.2017 / PubMed / Full text
- Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. / 04.2016 / PubMed / Full text
- Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. / 04.2015 / PubMed / Full text
- The benefits of staying active in old age: physical activity counteracts the negative influence of PICALM, BIN1, and CLU risk alleles on episodic memory functioning. / 06.2014 / PubMed / Full text
- BIN1 is decreased in sporadic but not familial Alzheimer's disease or in aging. / 2013 / PubMed / Full text
BMP4[править]
- Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. / 08.09.2020 / PubMed / Full text
- Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging. / 25.06.2019 / PubMed / Full text
- Centenarians Overexpress Pluripotency-Related Genes. / 16.08.2019 / PubMed / Full text
- BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence. / 15.11.2016 / PubMed / Full text
- Increased bone morphogenetic protein signaling contributes to age-related declines in neurogenesis and cognition. / 02.2016 / PubMed / Full text
- Control of the Normal and Pathological Development of Neural Stem and Progenitor Cells by the PC3/Tis21/Btg2 and Btg1 Genes. / 12.2015 / PubMed / Full text
- FSH-FSHR3-stem cells in ovary surface epithelium: basis for adult ovarian biology, failure, aging, and cancer. / 01.2015 / PubMed / Full text
- Molecular cloning and expression analysis of prostaglandin E receptor 2 gene in cashmere goat (Capra hircus) skin during hair follicle development. / 03.04.2014 / PubMed / Full text
C9[править]
- C9orf72 in myeloid cells suppresses STING-induced inflammation. / 09.2020 / PubMed / Full text
- Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain. / 16.12.2019 / PubMed / Full text
- Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity. / 12.2019 / PubMed / Full text
- Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population. / 2018 / PubMed / Full text
- TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity. / 07.2019 / PubMed / Full text
- C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons. / 29.08.2018 / PubMed / Full text
- Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text
- Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration. / 11.2013 / PubMed / Full text
CCL4[править]
- Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau. / 03.09.2018 / PubMed / Full text
- Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles. / 05.2018 / PubMed / Full text
- Human Body Composition and Immunity: Visceral Adipose Tissue Produces IL-15 and Muscle Strength Inversely Correlates with NK Cell Function in Elderly Humans. / 2018 / PubMed / Full text
- Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor. / 2018 / PubMed / Full text
- Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A receptor. / 18.10.2017 / PubMed / Full text
- Simultaneous time course analysis of multiple markers based on DNA microarray in incised wound in skeletal muscle for wound aging. / 09.2016 / PubMed / Full text
- Changes in the expression of the Toll-like receptor system in the aging rat kidneys. / 2014 / PubMed / Full text
- Age-related brain expression and regulation of the chemokine CCL4/MIP-1β in APP/PS1 double-transgenic mice. / 04.2014 / PubMed / Full text
CDK5[править]
- Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence. / 11.2019 / PubMed / Full text
- CK2 inhibition protects white matter from ischemic injury. / 20.11.2018 / PubMed / Full text
- CK2 inhibition confers functional protection to young and aging axons against ischemia by differentially regulating the CDK5 and AKT signaling pathways. / 06.2019 / PubMed / Full text
- The pathological roles of NDRG2 in Alzheimer's disease, a study using animal models and APPwt-overexpressed cells. / 08.2017 / PubMed / Full text
- APOE4 Induces Site-Specific Tau Phosphorylation Through Calpain-CDK5 Signaling Pathway in EFAD-Tg Mice. / 2016 / PubMed / Full text
- GENETICS OF HUMAN AGE RELATED DISORDERS. / 2015 / PubMed
- Surgical stress induces brain-derived neurotrophic factor reduction and postoperative cognitive dysfunction via glucocorticoid receptor phosphorylation in aged mice. / 05.2015 / PubMed / Full text
- Loss-of-SIRT1 function during vascular ageing: hyperphosphorylation mediated by cyclin-dependent kinase 5. / 02.2014 / PubMed / Full text
COL1A1[править]
- The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text
- Remodeling process in bone of aged rats in response to resistance training. / 01.09.2020 / PubMed / Full text
- Diet enrichment with a specific essential free amino acid mixture improves healing of undressed wounds in aged rats. / 01.10.2017 / PubMed / Full text
- Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts. / 01.06.2017 / PubMed / Full text
- Scleraxis Is Essential for Tendon Differentiation by Equine Embryonic Stem Cells and in Equine Fetal Tenocytes. / 15.03.2017 / PubMed / Full text
- The comparison of microRNA profile of the dermis between the young and elderly. / 05.2016 / PubMed / Full text
- Molecular differences between stromal cell populations from deciduous and permanent human teeth. / 18.04.2015 / PubMed / Full text
- Relationship of age and body mass index to the expression of obesity and osteoarthritis-related genes in human meniscus. / 09.2013 / PubMed / Full text
COMP[править]
- Effect of circadian rhythm, age, training and acute lameness on serum concentrations of cartilage oligomeric matrix protein (COMP) neo-epitope in horses. / 09.2019 / PubMed / Full text
- Genetic overexpression of COMP-Ang1 impairs BM microenvironment and induces senescence of BM HSCs. / 15.05.2018 / PubMed / Full text
- Longitudinal Twin Study of Subjective Health: Differences in Genetic and Environmental Components of Variance Across Age and Sex. / 01.01.2020 / PubMed / Full text
- Cartilage biomarkers in the osteoarthropathy of alkaptonuria reveal low turnover and accelerated ageing. / 01.2017 / PubMed / Full text
- Scleraxis Is Essential for Tendon Differentiation by Equine Embryonic Stem Cells and in Equine Fetal Tenocytes. / 15.03.2017 / PubMed / Full text
- Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence. / 16.09.2016 / PubMed / Full text
- Fibrotic-like changes in degenerate human intervertebral discs revealed by quantitative proteomic analysis. / 03.2016 / PubMed / Full text
- Enhanced tissue regeneration potential of juvenile articular cartilage. / 11.2013 / PubMed / Full text
CYP1A2[править]
- Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats. / 2019 / PubMed / Full text
- Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of CYP1A2-Mediated Pharmacokinetics in Young and Elderly Chinese Adults. / 07.2019 / PubMed / Full text
- Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. / 12.2017 / PubMed / Full text
- Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits. / 06.2017 / PubMed / Full text
- Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages. / 05.2017 / PubMed / Full text
- Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants. / 06.2017 / PubMed / Full text
- [Age-dependent CYP1A2 gene polymorphism -163C>A in three ethnic groups of Bashkortostan Republic residents]. / 2014 / PubMed
- Age-related changes in hepatic activity and expression of detoxification enzymes in male rats. / 2013 / PubMed / Full text
CYP2C19[править]
- Physiologically Based Pharmacokinetic Approach Can Successfully Predict Pharmacokinetics of Citalopram in Different Patient Populations. / 04.2020 / PubMed / Full text
- Longitudinal exposure of English primary care patients to pharmacogenomic drugs: An analysis to inform design of pre-emptive pharmacogenomic testing. / 12.2019 / PubMed / Full text
- The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers. / 05.2018 / PubMed / Full text
- Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. / 12.2017 / PubMed / Full text
- Analysis of the variability of the pharmacokinetics of multiple drugs in young adult and elderly subjects and its implications for acceptable daily exposures and cleaning validation limits. / 06.2017 / PubMed / Full text
- Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages. / 05.2017 / PubMed / Full text
- Identifying clinically relevant sources of variability: The clopidogrel challenge. / 02.2017 / PubMed / Full text
- Impact of age on serum concentrations of venlafaxine and escitalopram in different CYP2D6 and CYP2C19 genotype subgroups. / 08.2014 / PubMed / Full text
DCN[править]
- Decorin inhibits the insulin-like growth factor I signaling in bone marrow mesenchymal stem cells of aged humans. / 26.11.2020 / PubMed / Full text
- Classification of neurons in the adult mouse cochlear nucleus: Linear discriminant analysis. / 2019 / PubMed / Full text
- The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity. / 06.2019 / PubMed / Full text
- MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway. / 15.04.2019 / PubMed / Full text
- Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?: A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats. / 02.2019 / PubMed / Full text
- Extracellular proteoglycan decorin maintains human hair follicle stem cells. / 12.2018 / PubMed / Full text
- Synaptic Specializations Support Frequency-Independent Purkinje Cell Output from the Cerebellar Cortex. / 20.12.2016 / PubMed / Full text
- The aging human cochlear nucleus: Changes in the glial fibrillary acidic protein, intracellular calcium regulatory proteins, GABA neurotransmitter and cholinergic receptor. / 03.2014 / PubMed / Full text
DNMT3B[править]
- Collagens and DNA methyltransferases in mare endometrosis. / 09.2019 / PubMed / Full text
- Alcohol Extracts From [i]Ganoderma lucidum[/i] Delay the Progress of Alzheimer's Disease by Regulating DNA Methylation in Rodents. / 2019 / PubMed / Full text
- Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text
- Effects of Parental Aging During Embryo Development and Adult Life: The Case of Nothobranchius furzeri. / 04.2018 / PubMed / Full text
- Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. / 01.09.2017 / PubMed / Full text
- Forkhead box A2 regulates biliary heterogeneity and senescence during cholestatic liver injury in mice‡. / 02.2017 / PubMed / Full text
- Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study. / 08.2016 / PubMed / Full text
- Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy. / 10.2016 / PubMed / Full text
ESR1[править]
- Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement. / 05.01.2018 / PubMed / Full text
- Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain. / 01.04.2018 / PubMed / Full text
- Age- and menopause-related differences in subcutaneous adipose tissue estrogen receptor mRNA expression. / 05.2017 / PubMed / Full text
- Association of PvuII and XbaI polymorphisms on estrogen receptor alpha (ESR1) gene to changes into serum lipid profile of post-menopausal women: Effects of aging, body mass index and breast cancer incidence. / 2017 / PubMed / Full text
- Differential roles of estrogen receptors, ESR1 and ESR2, in adult rat spermatogenesis. / 15.06.2016 / PubMed / Full text
- Brain volumes in late life: gender, hormone treatment, and estrogen receptor variants. / 03.2014 / PubMed / Full text
- Prospective analysis of the association between estrogen receptor gene variants and the risk of cognitive decline in elderly women. / 12.2013 / PubMed / Full text
- Estrogen receptor alpha single nucleotide polymorphism as predictor of diabetes type 2 risk in hypogonadal men. / 06.2013 / PubMed / Full text
ESR2[править]
- Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain. / 01.04.2018 / PubMed / Full text
- Age- and menopause-related differences in subcutaneous adipose tissue estrogen receptor mRNA expression. / 05.2017 / PubMed / Full text
- Differential roles of estrogen receptors, ESR1 and ESR2, in adult rat spermatogenesis. / 15.06.2016 / PubMed / Full text
- Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. / 2015 / PubMed / Full text
- Estrogen receptor β variants modify risk for Alzheimer's disease in a multiethnic female cohort. / 2014 / PubMed / Full text
- Brain volumes in late life: gender, hormone treatment, and estrogen receptor variants. / 03.2014 / PubMed / Full text
- Prospective analysis of the association between estrogen receptor gene variants and the risk of cognitive decline in elderly women. / 12.2013 / PubMed / Full text
- Estrogen receptor alpha single nucleotide polymorphism as predictor of diabetes type 2 risk in hypogonadal men. / 06.2013 / PubMed / Full text
FAAH[править]
- Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice. / 02.2020 / PubMed / Full text
- Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. / 05.2019 / PubMed / Full text
- Stimulation of brain glucose uptake by cannabinoid CB2 receptors and its therapeutic potential in Alzheimer's disease. / 11.2016 / PubMed / Full text
- Sustained Endocannabinoid Signaling Compromises Decidual Function and Promotes Inflammation-induced Preterm Birth. / 08.04.2016 / PubMed / Full text
- Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development. / 03.2017 / PubMed / Full text
- Enhanced microglial activity in FAAH(-/-) animals. / 01.10.2015 / PubMed / Full text
- Normal aging in rats and pathological aging in human Alzheimer's disease decrease FAAH activity: modulation by cannabinoid agonists. / 12.2014 / PubMed / Full text
- Induction of endocannabinoid levels in juvenile rat brain following developmental chlorpyrifos exposure. / 09.2013 / PubMed / Full text
GBA[править]
- Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease. / 08.11.2019 / PubMed / Full text
- [i]Malassezia[/i] and Parkinson's Disease. / 2019 / PubMed / Full text
- Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain. / 07.2018 / PubMed / Full text
- GBA mutations in Parkinson disease: earlier death but similar neuropathological features. / 11.2017 / PubMed / Full text
- Cognitive and motor functioning in elderly glucocerebrosidase mutation carriers. / 10.2017 / PubMed / Full text
- Age and gender-specific reference intervals for lysosomal enzymes in dried blood spot samples: A study in Indian population. / 10.2017 / PubMed / Full text
- Minos-insertion mutant of the Drosophila GBA gene homologue showed abnormal phenotypes of climbing ability, sleep and life span with accumulation of hydroxy-glucocerebroside. / 30.05.2017 / PubMed / Full text
- Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes. / 12.2017 / PubMed / Full text
GLA[править]
- TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25. / 17.05.2018 / PubMed / Full text
- Gamma-linolenic acid ameliorated glycation-induced memory impairment in rats. / 12.2017 / PubMed / Full text
- Age and gender-specific reference intervals for lysosomal enzymes in dried blood spot samples: A study in Indian population. / 10.2017 / PubMed / Full text
- Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes. / 12.2017 / PubMed / Full text
- In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant. / 07.2016 / PubMed / Full text
- The stimulatory effect of the TLR4-mediated adjuvant glucopyranosyl lipid A is well preserved in old age. / 02.2016 / PubMed / Full text
- Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. / 06.2014 / PubMed / Full text
- Protective effect of borage seed oil and gamma linolenic acid on DNA: in vivo and in vitro studies. / 2013 / PubMed / Full text
GPI[править]
- Blood factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain. / 10.07.2020 / PubMed / Full text
- Potential role of exercise-induced glucose-6-phosphate isomerase in skeletal muscle function. / 30.06.2019 / PubMed / Full text
- Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria. / 2019 / PubMed / Full text
- Can the health of a nation be correlated to its state of internal peace? / 01-03.2016 / PubMed / Full text
- Developmental role of the cell adhesion molecule Contactin-6 in the cerebral cortex and hippocampus. / 03.07.2016 / PubMed / Full text
- Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus). / 11.2015 / PubMed / Full text
- Urokinase receptor and resistance to targeted anticancer agents. / 2015 / PubMed / Full text
- The glycolytic enzyme, GPI, is a functionally conserved modifier of dopaminergic neurodegeneration in Parkinson's models. / 01.07.2014 / PubMed / Full text
GSS[править]
- Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS. / 06.2020 / PubMed / Full text
- Geriatric brain tumor management part I: Meningioma. / 09.2019 / PubMed / Full text
- Link between cardiac function and the antioxidative defense mechanism in aged rats. / 11.06.2019 / PubMed / Full text
- Towards improving sterile insect technique: Exposure to orange oil compounds increases sexual signalling and longevity in Ceratitis capitata males of the Vienna 8 GSS. / 2017 / PubMed / Full text
- Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling. / 2015 / PubMed / Full text
- Comparison of Anastrepha ludens (Diptera: Tephritidae) Bisexual and Genetic Sexing (Tapachula-7) Strains: Effect of Hypoxia, Fly Density, Chilling Period, and Food Type on Fly Quality. / 04.2016 / PubMed / Full text
- The Geriatric Scoring System (GSS) for Risk Stratification in Meningioma Patients as a Predictor of Outcome in Patients Treated with Radiosurgery. / 03.2016 / PubMed / Full text
- 'Start to finish trans-institutional transdisciplinary care': a novel approach improves colorectal surgical results in frail elderly patients. / 01.2016 / PubMed / Full text
GSTM1[править]
- The effects of everyday-life exposure to polycyclic aromatic hydrocarbons on biological age indicators. / 03.12.2020 / PubMed / Full text
- Carrying the T Allele of the SNP rs574344, an eQTL of GSTM1, Contributes to Longevity in the Han Chinese Population. / 01.2019 / PubMed / Full text
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
- Aging-dependent DNA hypermethylation and gene expression of GSTM1 involved in T cell differentiation. / 25.07.2017 / PubMed / Full text
- [Age features of cytogenetic effects of spring-summer encephalitis among residents of northern western Siberia in connection with polymorphism for genes of glutathione-S-transferase]. / 2016 / PubMed
- Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. / 2016 / PubMed / Full text
- Effects of APOE rs429358, rs7412 and GSTM1/GSTT1 Polymorphism on Plasma and Erythrocyte Antioxidant Parameters and Cognition in Old Chinese Adults. / 24.09.2015 / PubMed / Full text
- [Frequency of gene polymorphic variants (phase II) of biotransformation of GSTT1 and GSTM1 xenobiotics among long-livers (Precarpathian region)]. / 2013 / PubMed
HFE[править]
- Polyphenol Characterization and Skin-Preserving Properties of Hydroalcoholic Flower Extract from [i]Himantoglossum robertianum[/i] (Orchidaceae). / 14.11.2019 / PubMed / Full text
- Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-F10 cells by inducing senescence. / 15.07.2018 / PubMed / Full text
- Iron-processing genotypes, nutrient intakes, and cadmium levels in the Normative Aging Study: Evidence of sensitive subpopulations in cadmium risk assessment. / 10.2018 / PubMed / Full text
- Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. / 2016 / PubMed / Full text
- Haplotype analysis of the HFE gene among populations of Northern Eurasia, in patients with metabolic disorders or stomach cancer, and in long-lived people. / 17.06.2016 / PubMed / Full text
- No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes. / 06.2016 / PubMed / Full text
- Cumulative lead exposure is associated with reduced olfactory recognition performance in elderly men: The Normative Aging Study. / 07.2015 / PubMed / Full text
- [[[CCR5]], CCR2, apoe, p53, ITGB3 and HFE gene polymorphism in Western Siberia long-livers]. / 2012 / PubMed
HMOX1[править]
- Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism. / 06.11.2020 / PubMed / Full text
- Well-aging: A new strategy for skin homeostasis under multi-stressed conditions. / 02.2020 / PubMed / Full text
- Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. / 08.2019 / PubMed / Full text
- Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. / 2016 / PubMed / Full text
- Exercise-induced Nrf2-signaling is impaired in aging. / 07.2016 / PubMed / Full text
- Behaviour and cognitive changes correlated with hippocampal neuroinflammaging and neuronal markers in female SAMP8, a model of accelerated senescence. / 07.2016 / PubMed / Full text
- Neurotherapeutic effects of novel HO-1 inhibitors in vitro and in a transgenic mouse model of Alzheimer's disease. / 12.2014 / PubMed / Full text
- Astroglial heme oxygenase-1 and the origin of corpora amylacea in aging and degenerating neural tissues. / 04.2014 / PubMed / Full text
LBR[править]
- Lamin B receptor: role on chromatin structure, cellular senescence and possibly aging. / 31.07.2020 / PubMed / Full text
- The impact of age beyond ploidy: outcome data from 8175 euploid single embryo transfers. / 03.2020 / PubMed / Full text
- The role of lamin B receptor in the regulation of senescence-associated secretory phenotype (SASP). / 01.05.2020 / PubMed / Full text
- Lamin B receptor plays a key role in cellular senescence induced by inhibition of the proteasome. / 11.12.2019 / PubMed / Full text
- Lamin B receptor (LBR) is involved in the induction of cellular senescence in human cells. / 03.2019 / PubMed / Full text
- Consequences of Lamin B1 and Lamin B Receptor Downregulation in Senescence. / 06.02.2018 / PubMed / Full text
- Overexpression of Lamin B Receptor Results in Impaired Skin Differentiation. / 2015 / PubMed / Full text
- Embryonic expression of the common progeroid lamin A splice mutation arrests postnatal skin development. / 04.2014 / PubMed / Full text
LPL[править]
- Survival analyses in Holstein cows considering direct disease diagnoses and specific SNP marker effects. / 09.2020 / PubMed / Full text
- Influence of common health disorders on the length of productive life and stayability in German Holstein cows. / 01.2020 / PubMed / Full text
- GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling. / 07.2018 / PubMed / Full text
- Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle. / 29.06.2017 / PubMed / Full text
- Association of Metabolic Syndrome with Serum Adipokines in Community-Living Elderly Japanese Women: Independent Association with Plasminogen Activator-Inhibitor-1. / 11.2015 / PubMed / Full text
- Moderate Exercise Mitigates the Detrimental Effects of Aging on Tendon Stem Cells. / 2015 / PubMed / Full text
- Association of adiponectin with serum preheparin lipoprotein lipase mass in women independent of fat mass and distribution, insulin resistance, and inflammation. / 10.2014 / PubMed / Full text
- [Clinical and genetic characteristics of long-livers in Moscow region]. / 2013 / PubMed
LTA[править]
- Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice. / 02.2020 / PubMed / Full text
- The change of pain classes over time: a latent transition analysis. / 02.2020 / PubMed / Full text
- Leisure time activities as mediating variables in functional disability progression: An application of parallel latent growth curve modeling. / 2018 / PubMed / Full text
- The Neighborhood Built Environment and Cognitive Function of Older Persons: Results from the Singapore Longitudinal Ageing Study. / 2018 / PubMed / Full text
- Changes in depression among older adults in China: A latent transition analysis. / 02.2017 / PubMed / Full text
- Joint effect of gene-physical activity and the interactions among CRP, TNF-α, and LTA polymorphisms on serum CRP, TNF-α levels, and handgrip strength in community-dwelling elders in Taiwan - TCHS-E. / 04.2016 / PubMed / Full text
- In vitro anti-platelet potency of ticagrelor in blood samples from infants and children. / 09.2015 / PubMed / Full text
- Physical Activity, Mediterranean Diet and Biomarkers-Assessed Risk of Alzheimer's: A Multi-Modality Brain Imaging Study. / 10.2014 / PubMed / Full text
MAG[править]
- Exploration of life satisfaction of Korean people with sensory impairments across the lifespan. / 10.2020 / PubMed / Full text
- Omega-3 Monoacylglyceride Effects on Longevity, Mitochondrial Metabolism and Oxidative Stress: Insights from [i]Drosophila melanogaster[/i]. / 16.11.2018 / PubMed / Full text
- Glial Sulfatides and Neuronal Complex Gangliosides Are Functionally Interdependent in Maintaining Myelinating Axon Integrity. / 02.01.2019 / PubMed / Full text
- Gray Matter Volume and Cognitive Performance During Normal Aging. A Voxel-Based Morphometry Study. / 2018 / PubMed / Full text
- Oxidative Stress Function in Women over 40 Years of Age, Considering Their Lifestyle. / 2017 / PubMed / Full text
- Age-related changes in retinoic, docosahexaenoic and arachidonic acid modulation in nuclear lipid metabolism. / 15.08.2016 / PubMed / Full text
- Transcriptional and biochemical responses of monoacylglycerol acyltransferase-mediated oil synthesis and associated senescence-like responses in Nicotiana benthamiana. / 2014 / PubMed / Full text
- Electromechanical delay of the knee extensor muscles: comparison among young, middle-age and older individuals. / 07.2015 / PubMed / Full text
MITF[править]
- Thymocid , a Standardized Black Cumin ([i]Nigella sativa[/i]) Seed Extract, Modulates Collagen Cross-Linking, Collagenase and Elastase Activities, and Melanogenesis in Murine B16F10 Melanoma Cells. / 19.07.2020 / PubMed / Full text
- HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth. / 21.05.2020 / PubMed / Full text
- Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells. / 01.2020 / PubMed / Full text
- H O promotes the aging process of melanogenesis through modulation of MITF and Nrf2. / 04.2019 / PubMed / Full text
- Deregulated MITF sumoylation: A route to melanoma. / 2017 / PubMed / Full text
- Phosphorylation of MITF by AKT affects its downstream targets and causes TP53-dependent cell senescence. / 11.2016 / PubMed / Full text
- Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations. / 23.02.2016 / PubMed / Full text
- Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma. / 06.2014 / PubMed / Full text
NNT[править]
- Yoga, Health-Related Quality of Life and Mental Well-Being: A Re-analysis of a Meta-analysis Using the Quality Effects Model. / 16.09.2020 / PubMed / Full text
- Statins After Myocardial Infarction in the Oldest: A Cohort Study in the Clinical Practice Research Datalink Database. / 02.2020 / PubMed / Full text
- Years of Life Lost for Older Patients After Colorectal Cancer Diagnosis. / 08.2019 / PubMed / Full text
- Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet. / 12.2018 / PubMed / Full text
- Upregulation of mitochondrial NAD levels impairs the clonogenicity of SSEA1 glioblastoma tumor-initiating cells. / 09.06.2017 / PubMed / Full text
- The Health Gain Obtainable from Pancreatic Resection for Adenocarcinoma in the Elderly. / 04.2017 / PubMed / Full text
- Restoration of Mitochondrial NAD Levels Delays Stem Cell Senescence and Facilitates Reprogramming of Aged Somatic Cells. / 12.2016 / PubMed / Full text
- Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons. / 08.2014 / PubMed / Full text
NOS2[править]
- Metformin alters peripheral blood mononuclear cells (PBMC) senescence biomarkers gene expression in type 2 diabetic patients. / 01.2021 / PubMed / Full text
- Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
- Secreted α-Klotho maintains cartilage tissue homeostasis by repressing [i]NOS2[/i] and [i]ZIP8-MMP13[/i] catabolic axis. / 19.06.2018 / PubMed / Full text
- Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging. / 28.12.2016 / PubMed / Full text
- All-trans retinoic acid (ATRA) prevents lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment in aged rats. / 15.11.2016 / PubMed / Full text
- TNFα antagonization alters NOS2 dependent nasopharyngeal carcinoma tumor growth. / 07.2015 / PubMed / Full text
- Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli. / 09.04.2015 / PubMed / Full text
- Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans. / 04.2013 / PubMed / Full text
NPS[править]
- Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging. / 28.03.2019 / PubMed / Full text
- Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults. / 08.2019 / PubMed / Full text
- The course of neuropsychiatric symptoms in patients with dementia in primary care. / 31.07.2019 / PubMed / Full text
- Serum calcium levels and neuropsychological performance in depression and matched healthy controls: Reversal of correlation a marker of the aging cognitive clock? / 05.2018 / PubMed / Full text
- Persistent use of psychotropic drugs in nursing home residents in Norway. / 13.02.2017 / PubMed / Full text
- FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging. / 14.07.2016 / PubMed / Full text
- Cardiorenal fibrosis and dysfunction in aging: Imbalance in mediators and regulators of collagen. / 02.2016 / PubMed / Full text
- Personalized technology to support older adults with and without cognitive impairment living at home. / 02.2015 / PubMed / Full text
PDE4C[править]
- Age prediction in living: Forensic epigenetic age estimation based on blood samples. / 11.2020 / PubMed / Full text
- Age Estimation Based on DNA Methylation Using Blood Samples From Deceased Individuals. / 03.2020 / PubMed / Full text
- Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. / 04.2018 / PubMed / Full text
- Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system. / 09.2016 / PubMed / Full text
- Plasma Amyloid Beta 1-42 and DNA Methylation Pattern Predict Accelerated Aging in Young Subjects with Down Syndrome. / 12.2016 / PubMed / Full text
- Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model. / 03.2016 / PubMed / Full text
- Improved age determination of blood and teeth samples using a selected set of DNA methylation markers. / 2015 / PubMed / Full text
- Aging of blood can be tracked by DNA methylation changes at just three CpG sites. / 03.02.2014 / PubMed / Full text
PDK1[править]
- Inhibition of 3-phosphoinositide-dependent protein kinase 1 (PDK1) can revert cellular senescence in human dermal fibroblasts. / 08.12.2020 / PubMed / Full text
- The Impact of the PI3K/Akt Signaling Pathway in Anxiety and Working Memory in Young and Middle-Aged PDK1 K465E Knock-In Mice. / 2020 / PubMed / Full text
- Peripheral Circulating Exosomal miRNAs Potentially Contribute to the Regulation of Molecular Signaling Networks in Aging. / 11.03.2020 / PubMed / Full text
- Vps15 is critical to mediate autophagy in AngII treated HUVECs probably by PDK1/PKC signaling pathway. / 15.09.2019 / PubMed / Full text
- Acupuncture Administration Improves Cognitive Functions and Alleviates Inflammation and Nuclear Damage by Regulating Phosphatidylinositol 3 Kinase (PI3K)/Phosphoinositol-Dependent Kinase 1 (PDK1)/Novel Protein Kinase C (nPKC)/Rac 1 Signaling Pathway in Senescence-Accelerated Prone 8 (SAM-P8) Mice. / 01.06.2019 / PubMed / Full text
- Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species. / 2017 / PubMed / Full text
- Selective deletion of Pten in theca-interstitial cells leads to androgen excess and ovarian dysfunction in mice. / 15.03.2017 / PubMed / Full text
- Serine- and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging. / 02.2014 / PubMed / Full text
PPID[править]
- Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population. / 03.2020 / PubMed / Full text
- Epidemiology of pituitary pars intermedia dysfunction: A systematic literature review of clinical presentation, disease prevalence and risk factors. / 05.2018 / PubMed / Full text
- Effect of Age, Season, Body Condition, and Endocrine Status on Serum Free Cortisol Fraction and Insulin Concentration in Horses. / 03-04.2016 / PubMed / Full text
- Age-related Qualitative Histological and Quantitative Stereological Changes in the Equine Pituitary. / 02-04.2016 / PubMed / Full text
- What's New in Old Horses? Postmortem Diagnoses in Mature and Aged Equids. / 03.2016 / PubMed / Full text
- Pituitary pars intermedia dysfunction does not necessarily impair insulin sensitivity in old horses. / 01.2015 / PubMed / Full text
- Evaluation of the effects of age and pituitary pars intermedia dysfunction on corneal sensitivity in horses. / 07.2013 / PubMed / Full text
- Comparison of hair follicle histology between horses with pituitary pars intermedia dysfunction and excessive hair growth and normal aged horses. / 02.2013 / PubMed / Full text
PSEN1[править]
- Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease. / 20.05.2016 / PubMed / Full text
- White Matter Abnormalities Track Disease Progression in PSEN1 Autosomal Dominant Alzheimer's Disease. / 2016 / PubMed / Full text
- Characterization of Amyloid-β Deposits in Bovine Brains. / 2016 / PubMed / Full text
- Functions of miR-9 and miR-9* during Aging in SAMP8 Mice and Their Possible Mechanisms. / 06.2015 / PubMed / Full text
- DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease. / 2015 / PubMed / Full text
- Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study. / 03.2015 / PubMed / Full text
- Age-dependent, non-cell-autonomous deposition of amyloid from synthesis of β-amyloid by cells other than excitatory neurons. / 05.03.2014 / PubMed / Full text
- Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors. / 20.10.2013 / PubMed / Full text
RAD50[править]
- ATM Deficiency Accelerates DNA Damage, Telomere Erosion, and Premature T Cell Aging in HIV-Infected Individuals on Antiretroviral Therapy. / 2019 / PubMed / Full text
- Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells. / 01.09.2018 / PubMed / Full text
- Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis. / 01.05.2017 / PubMed / Full text
- HIF-1α and rapamycin act as gerosuppressant in multiple myeloma cells upon genotoxic stress. / 17.08.2016 / PubMed / Full text
- Immunochip analysis identifies association of the RAD50/IL13 region with human longevity. / 06.2016 / PubMed / Full text
- Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. / 29.09.2015 / PubMed / Full text
- Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells. / 06.2015 / PubMed / Full text
- Copy neutral loss of heterozygosity is more frequent in older ovarian cancer patients. / 09.2013 / PubMed / Full text
SCT[править]
- Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults. / 10.2019 / PubMed / Full text
- High-intensity interval training improves acute plasma volume responses to exercise that is age dependent. / 02.2018 / PubMed / Full text
- Communication technology adoption among older adult veterans: the interplay of social and cognitive factors. / 12.2018 / PubMed / Full text
- Repeatability of Choroidal Thickness Measurements on Enhanced Depth Imaging Optical Coherence Tomography Using Different Posterior Boundaries. / 09.2016 / PubMed / Full text
- HIV cure strategies: how good must they be to improve on current antiretroviral therapy? / 2014 / PubMed / Full text
- Quadriceps intramuscular fat fraction rather than muscle size is associated with knee osteoarthritis. / 02.2014 / PubMed / Full text
- Robust measurement of telomere length in single cells. / 21.05.2013 / PubMed / Full text
- The effectiveness of stem cell therapies on health-related quality of life and life expectancy in comparison with conventional supportive medical treatment in patients suffering from end-stage liver disease. / 25.02.2013 / PubMed / Full text
SNCA[править]
- Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease. / 22.11.2019 / PubMed / Full text
- Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading. / 05.2020 / PubMed / Full text
- SerThr-PhosphoProteome of Brain from Aged PINK1-KO A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
- Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA). / 02.2020 / PubMed / Full text
- Caloric restriction rescues yeast cells from alpha-synuclein toxicity through autophagic control of proteostasis. / 07.12.2018 / PubMed / Full text
- Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats. / 06.2017 / PubMed / Full text
- DNA methylation levels of α-synuclein intron 1 in the aging brain. / 12.2015 / PubMed / Full text
- Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model. / 15.10.2013 / PubMed / Full text
SOD3[править]
- Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text
- Prenatal hypoxia affected endothelium-dependent vasodilation in mesenteric arteries of aged offspring via increased oxidative stress. / 06.2019 / PubMed / Full text
- Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage. / 2018 / PubMed / Full text
- In silico analysis and molecular dynamics simulation of human superoxide dismutase 3 (SOD3) genetic variants. / 03.2019 / PubMed / Full text
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
- Molecular evolutionary patterns of NAD /Sirtuin aging signaling pathway across taxa. / 2017 / PubMed / Full text
- Extracellular superoxide dismutase deficiency impairs wound healing in advanced age by reducing neovascularization and fibroblast function. / 03.2016 / PubMed / Full text
- Superoxide dismutase gene polymorphisms in patients with age-related cataract. / 09.2013 / PubMed / Full text
TIGIT[править]
- Association of Epigenetic Age and p16INK4a With Markers of T-Cell Composition in a Healthy Cohort. / 13.11.2020 / PubMed / Full text
- Implications of Immune Checkpoint Expression During Aging in HIV-Infected People on Antiretroviral Therapy. / 11-12.2019 / PubMed / Full text
- Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma. / 05.2019 / PubMed / Full text
- Multivariate Computational Analysis of Gamma Delta T Cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV Aging. / 2018 / PubMed / Full text
- Characterization of Blimp-1 function in effector regulatory T cells. / 07.2018 / PubMed / Full text
- T-cell Immunoglobulin and ITIM Domain Contributes to CD8 T-cell Immunosenescence. / 04.2018 / PubMed / Full text
- Long-Lived CD4 IFN-γ T Cells rather than Short-Lived CD4 IFN-γ IL-10 T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection. / 15.10.2016 / PubMed / Full text
- Combinatorial approach to cancer immunotherapy: strength in numbers. / 08.2016 / PubMed / Full text
TIMP1[править]
- Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis. / 26.10.2020 / PubMed / Full text
- Design, cyclization, and optimization of MMP13-TIMP1 interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis. / 01.2019 / PubMed / Full text
- Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9. / 2018 / PubMed / Full text
- Timing and duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1. / 04.2017 / PubMed / Full text
- Effect of TIMP1 transfection on PTEN expression in human kidney proximal tubular cells. / 21.12.2015 / PubMed / Full text
- Biological Effects Induced by Specific Advanced Glycation End Products in the Reconstructed Skin Model of Aging. / 2015 / PubMed / Full text
- Fat and Sucrose Intake Induces Obesity-Related Bone Metabolism Disturbances: Kinetic and Reversibility Studies in Growing and Adult Rats. / 01.2016 / PubMed / Full text
- Exercise training initiated in late middle age attenuates cardiac fibrosis and advanced glycation end-product accumulation in senescent rats. / 02.2014 / PubMed / Full text
TRPM2[править]
- Paraquat as an Environmental Risk Factor in Parkinson's Disease Accelerates Age-Related Degeneration Via Rapid Influx of Extracellular Zn into Nigral Dopaminergic Neurons. / 11.2019 / PubMed / Full text
- Pathophysiological Role of TRPM2 in Age-Related Cognitive Impairment in Mice. / 01.06.2019 / PubMed / Full text
- The TRPM2 channel nexus from oxidative damage to Alzheimer's pathologies: An emerging novel intervention target for age-related dementia. / 11.2018 / PubMed / Full text
- TRPM2 in the Brain: Role in Health and Disease. / 22.07.2018 / PubMed / Full text
- mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development. / 10.2018 / PubMed / Full text
- Prolactin protects retinal pigment epithelium by inhibiting sirtuin 2-dependent cell death. / 05.2016 / PubMed / Full text
- Extended therapeutic window of a novel peptide inhibitor of TRPM2 channels following focal cerebral ischemia. / 09.2016 / PubMed / Full text
- The Protective Role of Selenium on Scopolamine-Induced Memory Impairment, Oxidative Stress, and Apoptosis in Aged Rats: The Involvement of TRPM2 and TRPV1 Channels. / 05.2017 / PubMed / Full text
TRPV4[править]
- TRPV4 receptor as a functional sensory molecule in bladder urothelium: Stretch-independent, tissue-specific actions and pathological implications. / 01.2020 / PubMed / Full text
- Exercise restores impaired endothelium-derived hyperpolarizing factor-mediated vasodilation in aged rat aortic arteries via the TRPV4-K 2.3 signaling complex. / 2019 / PubMed / Full text
- Autonomic dysregulation at multiple sites is implicated in age-associated underactive bladder in female mice. / 06.2019 / PubMed / Full text
- Reduced bladder responses to capsaicin and GSK-1016790A in retired-breeder female rats with diminished volume sensitivity. / 01.11.2018 / PubMed / Full text
- Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis. / 08.07.2016 / PubMed / Full text
- Increasing TRPV4 expression restores flow-induced dilation impaired in mesenteric arteries with aging. / 07.03.2016 / PubMed / Full text
- Berberine via suppression of transient receptor potential vanilloid 4 channel improves vascular stiffness in mice. / 11.2015 / PubMed / Full text
- Age-related changes in the distribution of transient receptor potential vanilloid 4 channel (TRPV4) in the central nervous system of rats. / 10.2014 / PubMed / Full text
TSC2[править]
- AMPK/TSC2/mTOR pathway regulates replicative senescence of human vascular smooth muscle cells. / 12.2018 / PubMed / Full text
- Autophagy mediators (FOXO1, SESN3 and TSC2) in Lewy body disease and aging. / 25.09.2018 / PubMed / Full text
- FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling. / 25.03.2018 / PubMed / Full text
- Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. / 12.2017 / PubMed / Full text
- Complex inhibition of autophagy by mitochondrial aldehyde dehydrogenase shortens lifespan and exacerbates cardiac aging. / 08.2017 / PubMed / Full text
- Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells. / 01.08.2014 / PubMed / Full text
- mTOR inactivation by ROS-JNK-p53 pathway plays an essential role in psedolaric acid B induced autophagy-dependent senescence in murine fibrosarcoma L929 cells. / 05.09.2013 / PubMed / Full text
- Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models. / 09.2013 / PubMed / Full text
UCHL1[править]
- Abolishing UCHL1's hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice. / 04.11.2020 / PubMed / Full text
- FAM96B inhibits the senescence of dental pulp stem cells. / 05.2020 / PubMed / Full text
- Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence. / 2017 / PubMed / Full text
- Life and death in the trash heap: The ubiquitin proteasome pathway and UCHL1 in brain aging, neurodegenerative disease and cerebral Ischemia. / 03.2017 / PubMed / Full text
- Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system. / 07.2016 / PubMed / Full text
- Effect of age on expression of spermatogonial markers in bovine testis and isolated cells. / 07.2016 / PubMed / Full text
- It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease. / 2016 / PubMed / Full text
- Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system. / 2014 / PubMed / Full text
VDAC1[править]
- Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian longevity. / 07.2020 / PubMed / Full text
- 17β-estradiol inhibits H O -induced senescence in HUVEC cells through upregulating SIRT3 expression and promoting autophagy. / 10.2020 / PubMed / Full text
- Changes in the expression of oxidative phosphorylation complexes in the aging intestinal mucosa. / 01.07.2020 / PubMed / Full text
- Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice. / 05.12.2019 / PubMed / Full text
- Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. / 09.2019 / PubMed / Full text
- The Immp2l mutation causes age-dependent degeneration of cerebellar granule neurons prevented by antioxidant treatment. / 02.2016 / PubMed / Full text
- The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats. / 07.2015 / PubMed / Full text
- Curcumin prevents mitochondrial dysfunction in the brain of the senescence-accelerated mouse-prone 8. / 04.2013 / PubMed / Full text
XRCC1[править]
- Impairment of Pol β-related DNA Base-excision Repair Leads to Ovarian Aging in Mice. / 20.11.2020 / PubMed / Full text
- Base excision repair but not DNA double-strand break repair is impaired in aged human adipose-derived stem cells. / 02.2020 / PubMed / Full text
- [Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats]. / 07.2018 / PubMed / Full text
- The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity. / 2018 / PubMed / Full text
- XRCC1 and XPD genetic polymorphisms and susceptibility to age-related cataract: a meta-analysis. / 2015 / PubMed / Full text
- Polymorphisms of DNA repair genes XPD (Lys751Gln) and XRCC1 (Arg399Gln), and the risk of age-related cataract: a meta-analysis. / 07.2015 / PubMed / Full text
- Association between DNA repair genes (XPD and XRCC1) polymorphisms and susceptibility to age-related cataract (ARC): a meta-analysis. / 08.2014 / PubMed / Full text
- Polymorphisms in ERCC1 C8092A predict progression-free survival in metastatic/recurrent nasopharyngeal carcinoma treated with cisplatin-based chemotherapy. / 08.2013 / PubMed / Full text
AGA[править]
- Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II. / 11.2020 / PubMed / Full text
- Relationship between androgenic alopecia and white matter hyperintensities in apparently healthy subjects. / 04.2020 / PubMed / Full text
- ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed
- The Impact of Being Born Preterm or Small for Gestational Age on Early Vascular Aging in Adolescents. / 10.2018 / PubMed / Full text
- Adult height of preterm infants: a longitudinal cohort study. / 06.2017 / PubMed / Full text
- The telomere attrition rate is not accelerated in women born small for gestational age: A birth cohort study. / 05.02.2017 / PubMed / Full text
- Does prostaglandin D2 hold the cure to male pattern baldness? / 04.2014 / PubMed / Full text
ALB[править]
- Effects of Age on Inflammatory Profiles and Nutrition/Energy Metabolism in Domestic Cats. / 2020 / PubMed / Full text
- Expression of Transferrin and Albumin in the Sperm-Storage Tubules of Japanese Quail and their Possible Involvement in Long-Term Sperm Storage. / 25.01.2020 / PubMed / Full text
- Blood Chemistry Reference Values for Free-Ranging Asiatic Black Bears ( Ursus thibetanus) by Season, Age, and Sex. / 07.2018 / PubMed / Full text
- Higher serum albumin was related with diabetes incidence and the impact of BMI changes: Based on cohort study of 18,384 Chinese male elderly. / 12.2017 / PubMed / Full text
- Estimating the survival advantage based on telomere length and serum biomarkers of aging. / 01.08.2017 / PubMed / Full text
- HEMATOLOGY AND PLASMA CHEMISTRY OF THE PLOUGHSHARE TORTOISE (ASTROCHELYS YNIPHORA) IN A CAPTIVE BREEDING PROGRAM. / 03.2017 / PubMed / Full text
- Too old to have children? Lessons from natural fertility populations. / 06.2014 / PubMed / Full text
AMPH[править]
- Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood. / 01.09.2018 / PubMed / Full text
- The effects of amphetamine exposure on juvenile rats on the neuronal morphology of the limbic system at prepubertal, pubertal and postpubertal ages. / 11.2016 / PubMed / Full text
- Amphetamine modulates brain signal variability and working memory in younger and older adults. / 16.06.2015 / PubMed / Full text
- Adolescent exposure to cocaine, amphetamine, and methylphenidate cross-sensitizes adults to methamphetamine with drug- and sex-specific effects. / 15.03.2015 / PubMed / Full text
- Age of exposure-dependent effects of amphetamine on behavioral flexibility. / 01.09.2013 / PubMed / Full text
- Concurrent choice for social interaction and amphetamine using conditioned place preference in rats: effects of age and housing condition. / 01.05.2013 / PubMed / Full text
- Age-dependent effects of repeated amphetamine exposure on working memory in rats. / 01.04.2013 / PubMed / Full text
ATF3[править]
- ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. / 04.2018 / PubMed / Full text
- p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells. / 15.09.2017 / PubMed / Full text
- Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival. / 04.05.2017 / PubMed / Full text
- Rutin protects against aging-related metabolic dysfunction. / 02.2016 / PubMed / Full text
- Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age. / 2015 / PubMed / Full text
- Activation of autophagic pathways is related to growth inhibition and senescence in cutaneous squamous cell carcinoma. / 10.2014 / PubMed / Full text
- Age-related brain expression and regulation of the chemokine CCL4/MIP-1β in APP/PS1 double-transgenic mice. / 04.2014 / PubMed / Full text
ATG12[править]
- Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
- Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats. / 06.2017 / PubMed / Full text
- Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging. / 26.02.2017 / PubMed / Full text
- Autophagic homeostasis is required for the pluripotency of cancer stem cells. / 02.2017 / PubMed / Full text
- Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts. / 12.2016 / PubMed / Full text
- Follicle-stimulating hormone promotes age-related endometrial atrophy through cross-talk with transforming growth factor beta signal transduction pathway. / 04.2015 / PubMed / Full text
ATRX[править]
- ATRX-DAXX Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains. / 09.2019 / PubMed / Full text
- Inactivation of hepatic ATRX in [i]Atrx[/i] Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine. / 07.06.2018 / PubMed / Full text
- Mechanistic understanding of the role of ATRX in senescence provides new insight for combinatorial therapies with CDK4 inhibitors. / 2018 / PubMed / Full text
- GBM-associated mutations and altered protein expression are more common in young patients. / 25.10.2016 / PubMed / Full text
- Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes. / 01.2016 / PubMed / Full text
- MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition. / 10.04.2015 / PubMed / Full text
- Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. / 05.2013 / PubMed / Full text
CBL[править]
- Effects of cerebrolysin on nerve growth factor system in the aging rat brain. / 2017 / PubMed / Full text
- Skeletal Muscle CAP Expression Increases after Dietary Restriction and Aerobic Training in Women with a History of Gestational Diabetes. / 2016 / PubMed / Full text
- Intranasal Cerebrolysin Attenuates Learning and Memory Impairments in D-galactose-Induced Senescence in Mice. / 01.2017 / PubMed / Full text
- Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick's disease and fronto-temporal tauopathies. / 26.11.2015 / PubMed / Full text
- Cerebrolysin Accelerates Metamorphosis and Attenuates Aging-Accelerating Effect of High Temperature in Drosophila Melanogaster. / 01.10.2014 / PubMed / Full text
- Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure. / 21.07.2014 / PubMed / Full text
- Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry. / 03.2014 / PubMed / Full text
CCL20[править]
- Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: Sex differences and role of purinergic receptors. / 07.11.2020 / PubMed / Full text
- p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. / 06.2020 / PubMed / Full text
- Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly. / 02.2018 / PubMed / Full text
- Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists. / 15.08.2017 / PubMed / Full text
- Interferon-gamma deficiency protects against aging-related goblet cell loss. / 04.10.2016 / PubMed / Full text
- Age dependent changes in the LPS induced transcriptome of bovine dermal fibroblasts occurs without major changes in the methylome. / 27.01.2015 / PubMed / Full text
- Dendritic cells from aged subjects contribute to chronic airway inflammation by activating bronchial epithelial cells under steady state. / 11.2014 / PubMed / Full text
CPD[править]
- Incidental versus clinically diagnosed differentiated thyroid cancer in both adult and elderly subjects: histological characteristics and follow-up in a retrospective analysis from a single institution. / 06.2020 / PubMed / Full text
- Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease. / 05.2019 / PubMed / Full text
- What Do Clinical Supervisors Require to Teach Residents in Family Medicine How to Care for Seniors? / 03.2018 / PubMed / Full text
- Survey of Australasian geriatricians' satisfaction with, and preferences for, continuing professional development. / 07.2016 / PubMed / Full text
- The aging psychiatrist: lessons from our colleagues in surgery and anaesthesia. / 04.2016 / PubMed / Full text
- Effects of donor age and proliferative aging on the phenotype stability of rat aortic smooth muscle cells. / 11.2015 / PubMed / Full text
- Specificity of cytochemical and fluorescence methods of senescence-associated β-galactosidase detection for ageing driven by replication and time. / 08.2014 / PubMed / Full text
CSF1R[править]
- CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization. / 01.04.2020 / PubMed / Full text
- CSF1R inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice. / 02.02.2020 / PubMed / Full text
- Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units. / 05.11.2019 / PubMed / Full text
- Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge. / 26.11.2018 / PubMed / Full text
- Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice. / 12.2018 / PubMed / Full text
- Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text
- Pleiotropic effects of extended blockade of CSF1R signaling in adult mice. / 08.2014 / PubMed / Full text
CTSB[править]
- Myocardial cathepsin D is downregulated in sudden cardiac death. / 2020 / PubMed / Full text
- A Free Radical-Generating System Regulates Amyloid Oligomers: Involvement of Cathepsin B. / 2018 / PubMed / Full text
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
- Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice. / 03.04.2017 / PubMed / Full text
- Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function. / 09.08.2016 / PubMed / Full text
- The association of serum cathepsin B concentration with age-related cardiovascular-renal subclinical state in a healthy Chinese population. / 07-08.2016 / PubMed / Full text
- Decreased serum level of HMGB1 and MyD88 during human aging progress in healthy individuals. / 04.2016 / PubMed / Full text
CYP2E1[править]
- DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver. / 06.2020 / PubMed / Full text
- Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats. / 2019 / PubMed / Full text
- 2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. / 01.04.2019 / PubMed / Full text
- Neuroprotective Effect of Dioscin on the Aging Brain. / 30.03.2019 / PubMed / Full text
- Cytochrome P450-2E1 is involved in aging-related kidney damage in mice through increased nitroxidative stress. / 11.2017 / PubMed / Full text
- Cytochrome P450-2E1 promotes aging-related hepatic steatosis, apoptosis and fibrosis through increased nitroxidative stress. / 02.2016 / PubMed / Full text
- Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures. / 25.12.2015 / PubMed / Full text
DSP[править]
- Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions. / 10.2019 / PubMed / Full text
- Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. / 05.2018 / PubMed / Full text
- Metabolic Syndrome Components Are Associated With Symptomatic Polyneuropathy Independent of Glycemic Status. / 05.2016 / PubMed / Full text
- Analysis of diarrhetic shellfish poisoning toxins and pectenotoxin-2 in the bottlenose dolphin (Tursiops truncatus) by liquid chromatography-tandem mass spectrometry. / 16.10.2015 / PubMed / Full text
- Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances. / 15.11.2014 / PubMed / Full text
- Age-dependent clinical and genetic characteristics in Japanese patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia. / 2013 / PubMed / Full text
- Differences in susceptibility to okadaic acid, a diarrhetic shellfish poisoning toxin, between male and female mice. / 27.12.2012 / PubMed / Full text
FIS1[править]
- Alterations in Mitochondrial Dynamic-related Genes in the Peripheral Blood of Alzheimer's Disease Patients. / 2020 / PubMed / Full text
- A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. / 01.02.2019 / PubMed / Full text
- Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice. / 2018 / PubMed / Full text
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
- Effects of β-hydroxy-β-methylbutyrate on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults. / 01.11.2017 / PubMed / Full text
- Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity. / 03.2017 / PubMed / Full text
- Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan. / 2015 / PubMed / Full text
FOXP3[править]
- Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. / 21.12.2019 / PubMed / Full text
- Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text
- Enhanced expression of PD-1 and other activation markers by CD4 T cells of young but not old patients with metastatic melanoma. / 06.2018 / PubMed / Full text
- Non-linear patterns in age-related DNA methylation may reflect CD4 T cell differentiation. / 03.06.2017 / PubMed / Full text
- Novel Senescent Regulatory T-Cell Subset with Impaired Suppressive Function in Rheumatoid Arthritis. / 2017 / PubMed / Full text
- Age-related changes in CD4 CD25 FOXP3 regulatory T cells and their relationship with lung cancer. / 2017 / PubMed / Full text
- Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects. / 10.2016 / PubMed / Full text
GAP43[править]
- HDAC inhibition leads to age-dependent opposite regenerative effect upon PTEN deletion in rubrospinal axons after SCI. / 06.2020 / PubMed / Full text
- The Puzzling Role of Neuron-Specific PMCA Isoforms in the Aging Process. / 16.12.2019 / PubMed / Full text
- Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text
- Differential expression of synaptic and interneuron genes in the aging human prefrontal cortex. / 10.2018 / PubMed / Full text
- Schwann Cell Phenotype Changes in Aging Human Dental Pulp. / 03.2018 / PubMed / Full text
- Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex. / 01.01.2017 / PubMed / Full text
- Alterations of Ca²⁺-responsive proteins within cholinergic neurons in aging and Alzheimer's disease. / 06.2014 / PubMed / Full text
HCN4[править]
- Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels. / 05.2018 / PubMed / Full text
- Age-dependent down-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 4 causes deterioration of canine sinoatrial node function. / 01.05.2017 / PubMed / Full text
- Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes. / 11.11.2015 / PubMed / Full text
- Age-associated expression of HCN channel isoforms in rat sinoatrial node. / 02.2016 / PubMed / Full text
- Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation. / 09.2015 / PubMed / Full text
- Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. / 27.02.2015 / PubMed / Full text
- Association between reversal in the expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel and age-related atrial fibrillation. / 14.11.2014 / PubMed / Full text
HRAS[править]
- Pterostilbene Sensitizes Cisplatin-Resistant Human Bladder Cancer Cells with Oncogenic [i]HRAS[/i]. / 06.10.2020 / PubMed / Full text
- Catalog of Lung Cancer Gene Mutations Among Chinese Patients. / 2020 / PubMed / Full text
- How do combinations of unhealthy behaviors relate to attitudinal factors and subjective health among the adult population in the Netherlands? / 03.04.2020 / PubMed / Full text
- Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype. / 07.02.2020 / PubMed / Full text
- "Back to the future": Influence of beliefs regarding the future on TTO answers. / 12.01.2016 / PubMed / Full text
- Contributions of intrinsic mutation rate and selfish selection to levels of de novo HRAS mutations in the paternal germline. / 10.12.2013 / PubMed / Full text
- PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling. / 13.11.2014 / PubMed / Full text
IL2[править]
- Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus. / 2020 / PubMed / Full text
- Redox, immune and genetic biomarker system for personalized treatments in colorectal cancer. / 15.02.2019 / PubMed / Full text
- Low IL-2 Expressing T Cells in Thalassemia Major Patients: Is It Immune Aging. / 10.2018 / PubMed / Full text
- Epigenetic repression of interleukin 2 expression in senescent CD4 T cells during chronic HIV type 1 infection. / 01.01.2015 / PubMed / Full text
- Cytomegalovirus infection modulates the phenotype and functional profile of the T-cell immune response to mycobacterial antigens in older life. / 06.2014 / PubMed / Full text
- Propolis efficacy on TNF-α, IFN-γ and IL2 cytokines production in old mice with and without systemic candidiasis. / 09.2012 / PubMed / Full text
- The polyfunctionality of human memory CD8 T cells elicited by acute and chronic virus infections is not influenced by age. / 2012 / PubMed / Full text
KEAP1[править]
- Sex-, age-, and race/ethnicity-dependent variations in drug-processing and NRF2-regulated genes in human livers. / 08.11.2020 / PubMed / Full text
- NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands. / 09.2020 / PubMed / Full text
- Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds. / 18.05.2020 / PubMed / Full text
- Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression. / 2019 / PubMed / Full text
- Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1 -expressing ALS mouse model. / 29.05.2018 / PubMed / Full text
- Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates. / 04.2018 / PubMed / Full text
- The Anti-Aging Effect of Erythropoietin via the ERK/Nrf2-ARE Pathway in Aging Rats. / 03.2017 / PubMed / Full text
LRP1[править]
- Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome. / 06.2020 / PubMed / Full text
- LXR activation protects hippocampal microvasculature in very old triple transgenic mouse model of Alzheimer's disease. / 16.05.2016 / PubMed / Full text
- Rescuing effects of RXR agonist bexarotene on aging-related synapse loss depend on neuronal LRP1. / 03.2016 / PubMed / Full text
- Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats. / 20.05.2015 / PubMed / Full text
- Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice. / 10.10.2014 / PubMed / Full text
- LRP1 protects the vasculature by regulating levels of connective tissue growth factor and HtrA1. / 09.2013 / PubMed / Full text
- A lipoprotein receptor cluster IV mutant preferentially binds amyloid-β and regulates its clearance from the mouse brain. / 24.05.2013 / PubMed / Full text
NOS1[править]
- Prepubertal overexposure to manganese induce precocious puberty through GABA receptor/nitric oxide pathway in immature female rats. / 30.01.2020 / PubMed / Full text
- Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
- NOS3 Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels. / 11.07.2018 / PubMed / Full text
- NOS1 and SNAP25 polymorphisms are associated with Attention-Deficit/Hyperactivity Disorder symptoms in adults but not in children. / 04.2016 / PubMed / Full text
- NOS1 induces NADPH oxidases and impairs contraction kinetics in aged murine ventricular myocytes. / 09.2015 / PubMed / Full text
- Sex-dependent hypertension and renal changes in aged rats with altered renal development. / 15.08.2014 / PubMed / Full text
- Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans. / 04.2013 / PubMed / Full text
NOTCH1[править]
- [How Does Aging Contribute to Cancer?] / 09.2020 / PubMed
- H19 is not hypomethylated or upregulated with age or sex in the aortic valves of mice. / 10.2019 / PubMed / Full text
- Age-related remodelling of oesophageal epithelia by mutated cancer drivers. / 01.2019 / PubMed / Full text
- Dynamic regulation of NOTCH1 activation and Notch ligand expression in human thymus development. / 13.08.2018 / PubMed / Full text
- Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency. / 01.05.2017 / PubMed / Full text
- Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study. / 09.04.2016 / PubMed / Full text
- Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence. / 01.05.2013 / PubMed / Full text
NRAS[править]
- Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor. / 10.2020 / PubMed / Full text
- STAT3 Relays a Differential Response to Melanoma-Associated [i]NRAS[/i] Mutations. / 02.01.2020 / PubMed / Full text
- Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study. / 08.11.2019 / PubMed / Full text
- Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text
- ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A. / 24.03.2017 / PubMed / Full text
- Trametinib radiosensitises RAS- and BRAF-mutated melanoma by perturbing cell cycle and inducing senescence. / 11.2015 / PubMed / Full text
- Registered report: senescence surveillance of pre-malignant hepatocytes limits liver cancer development. / 26.01.2015 / PubMed / Full text
NTS[править]
- Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension. / 08.2019 / PubMed / Full text
- Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. / 01.08.2018 / PubMed / Full text
- Neural processing of basic tastes in healthy young and older adults - an fMRI study. / 01.10.2015 / PubMed / Full text
- Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity. / 05.2015 / PubMed / Full text
- Endogenous leptin contributes to baroreflex suppression within the solitary tract nucleus of aged rats. / 01.12.2014 / PubMed / Full text
- Central hydrogen sulphide mediates ventilatory responses to hypercapnia in adult conscious rats. / 11.2014 / PubMed / Full text
- Chronic intermittent hypoxia promotes expression of 3-mercaptopyruvate sulfurtransferase in adult rat medulla oblongata. / 12.2013 / PubMed / Full text
OGT[править]
- ELT-2 promotes O-GlcNAc transferase OGT-1 expression to modulate Caenorhabditis elegans lifespan. / 06.07.2020 / PubMed / Full text
- Neuronal O-GlcNAcylation Improves Cognitive Function in the Aged Mouse Brain. / 21.10.2019 / PubMed / Full text
- Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN. / 31.07.2018 / PubMed / Full text
- O-GlcNAcylation of SKN-1 modulates the lifespan and oxidative stress resistance in Caenorhabditis elegans. / 08.03.2017 / PubMed / Full text
- O-linked N-acetylglucosamine transferase (OGT) interacts with the histone chaperone HIRA complex and regulates nucleosome assembly and cellular senescence. / 07.06.2016 / PubMed / Full text
- Disruption of O-linked N-Acetylglucosamine Signaling Induces ER Stress and β Cell Failure. / 22.12.2015 / PubMed / Full text
- OGT and OGA expression in postmenopausal skeletal muscle associates with hormone replacement therapy and muscle cross-sectional area. / 12.2013 / PubMed / Full text
P2RY12[править]
- Potential caveats of putative microglia-specific markers for assessment of age-related cerebrovascular neuroinflammation. / 01.12.2020 / PubMed / Full text
- Microglial changes in the early aging stage in a healthy retina and an experimental glaucoma model. / 2020 / PubMed / Full text
- Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains. / 20.01.2020 / PubMed / Full text
- Age Influences Microglial Activation After Cuprizone-Induced Demyelination. / 2018 / PubMed / Full text
- Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text
- Transcriptomic analysis of purified human cortical microglia reveals age-associated changes. / 08.2017 / PubMed / Full text
- Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis. / 01.07.2017 / PubMed / Full text
PCSK9[править]
- Lipoprotein removal mechanisms and aging: implications for the cardiovascular health of the elderly. / 04.2020 / PubMed / Full text
- The role of proprotein convertase subtilisin-kexin type 9 (PCSK9) in the vascular aging process - is there a link? / 10.2019 / PubMed / Full text
- PCSK9 Inhibitors Show Value for Patients and the US Health Care System. / 12.2017 / PubMed / Full text
- Association between lipoprotein (a) and proprotein convertase substilisin/kexin type 9 in patients with heterozygous familial hypercholesterolemia: A case-control study. / 02.2018 / PubMed / Full text
- What's next for dyslipidemia management? The 2013 ACC/AHA Guidelines, the NLA recommendations, and beyond. / 05-06.2016 / PubMed / Full text
- Impact of age and sex on the development of atherosclerosis and expression of the related genes in apoE deficient mice. / 15.01.2016 / PubMed / Full text
- [[PCSK9]]: a key modulator of cardiovascular health. / 14.03.2014 / PubMed / Full text
PIK3CA[править]
- Catalog of Lung Cancer Gene Mutations Among Chinese Patients. / 2020 / PubMed / Full text
- Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway. / 10.06.2019 / PubMed / Full text
- Oncogenic mutations in histologically normal endometrium: the new normal? / 10.2019 / PubMed / Full text
- A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient. / 09.2019 / PubMed / Full text
- Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic PIK3CA accompanied with pro-tumorigenic secretome. / 01.08.2019 / PubMed / Full text
- Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text
- Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. / 2015 / PubMed / Full text
PYY[править]
- Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. / 09.2019 / PubMed / Full text
- Peptide YY (PYY) Is Expressed in Human Skeletal Muscle Tissue and Expanding Human Muscle Progenitor Cells. / 2019 / PubMed / Full text
- Peptide YY induces characteristic meal patterns of aged mice. / 11.2017 / PubMed / Full text
- Effects of randomized whey-protein loads on energy intake, appetite, gastric emptying, and plasma gut-hormone concentrations in older men and women. / 09.2017 / PubMed / Full text
- Glucagon-like peptide-1 (GLP-1) increases in plasma and colon tissue prior to estrus and circulating levels change with increasing age in reproductively competent Wistar rats. / 04.2017 / PubMed / Full text
- Increased peptide YY blood concentrations, not decreased acyl-ghrelin, are associated with reduced hunger and food intake in healthy older women: Preliminary evidence. / 01.10.2016 / PubMed / Full text
- Anorexigenic postprandial responses of PYY and GLP1 to slow ice cream consumption: preservation in obese adolescents, but not in obese adults. / 03.2013 / PubMed / Full text
RIPK3[править]
- Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. / 18.11.2020 / PubMed / Full text
- Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. / 05.2020 / PubMed / Full text
- Metformin mediates cardioprotection against aging-induced ischemic necroptosis. / 02.2020 / PubMed / Full text
- A small molecule Nec-1 directly induces amyloid clearance in the brains of aged APP/PS1 mice. / 12.03.2019 / PubMed / Full text
- RIP kinases as modulators of inflammation and immunity. / 09.2018 / PubMed / Full text
- Necroptosis increases with age and is reduced by dietary restriction. / 08.2018 / PubMed / Full text
- RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system. / 15.08.2017 / PubMed / Full text
ROCK1[править]
- Disruption of both ROCK1 and ROCK2 genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging. / 06.2019 / PubMed / Full text
- Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text
- Vascular Smooth Muscle Contractile Function Declines With Age in Skeletal Muscle Feed Arteries. / 2018 / PubMed / Full text
- Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1. / 01-02.2017 / PubMed / Full text
- Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis. / 14.01.2016 / PubMed / Full text
- Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle. / 15.10.2015 / PubMed / Full text
- miR-135a modulates tendon stem/progenitor cell senescence via suppressing ROCK1. / 02.2015 / PubMed / Full text
RUNX1[править]
- RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins. / 03.2018 / PubMed / Full text
- Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text
- Conversion of adult endothelium to immunocompetent haematopoietic stem cells. / 25.05.2017 / PubMed / Full text
- Resistance Training Enhances Skeletal Muscle Innervation Without Modifying the Number of Satellite Cells or their Myofiber Association in Obese Older Adults. / 10.2016 / PubMed / Full text
- Epigenetic Aging Signatures Are Coherently Modified in Cancer. / 06.2015 / PubMed / Full text
- Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex. / 08.2015 / PubMed / Full text
- Runx3 deficiency results in myeloproliferative disorder in aged mice. / 25.07.2013 / PubMed / Full text
SET[править]
- Two conserved epigenetic regulators prevent healthy ageing. / 03.2020 / PubMed / Full text
- Chromatin Modifiers SET-25 and SET-32 Are Required for Establishment but Not Long-Term Maintenance of Transgenerational Epigenetic Inheritance. / 20.11.2018 / PubMed / Full text
- SET-9 and SET-26 are H3K4me3 readers and play critical roles in germline development and longevity. / 01.05.2018 / PubMed / Full text
- Muscle-Specific Histone H3K36 Dimethyltransferase SET-18 Shortens Lifespan of Caenorhabditis elegans by Repressing daf-16a Expression. / 06.03.2018 / PubMed / Full text
- Assessing efficacy of day 3 embryo time-lapse algorithms retrospectively: impacts of dataset type and confounding factors. / 09.2019 / PubMed / Full text
- CONSTANCES: a general prospective population-based cohort for occupational and environmental epidemiology: cohort profile. / 01.2017 / PubMed / Full text
- A non-canonical role for the C. elegans dosage compensation complex in growth and metabolic regulation downstream of TOR complex 2. / 09.2013 / PubMed / Full text
SLA[править]
- Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity. / 14.07.2020 / PubMed / Full text
- Mechanical Anisotropy and Surface Roughness in Additively Manufactured Parts Fabricated by Stereolithography (SLA) Using Statistical Analysis. / 30.05.2020 / PubMed / Full text
- The Effect of Age of Titanium Dental Implants on Implant Survival and Marginal Bone Resorption: A 5-Year Retrospective Follow-Up Study. / 01.10.2020 / PubMed / Full text
- "Spirometric" lung age reference equations: A narrative review. / 01.2018 / PubMed / Full text
- Relative growth rate in phylogenetically related deciduous and evergreen woody species. / 07.2001 / PubMed / Full text
- Leaf lifespan as a determinant of leaf structure and function among 23 amazonian tree species. / 03.1991 / PubMed / Full text
- The Performance of Titanium-Zirconium Implants in the Elderly: A Biomechanical Comparative Study in the Minipig. / 12.2016 / PubMed / Full text
SLC6A4[править]
- The Psilocybin-Telomere Hypothesis: An empirically falsifiable prediction concerning the beneficial neuropsychopharmacological effects of psilocybin on genetic aging. / 01.2020 / PubMed / Full text
- Epigenetics-by-sex interaction for somatization conferred by methylation at the promoter region of SLC6A4 gene. / 08.03.2019 / PubMed / Full text
- Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text
- DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) genes are associated with anxiety/depression in older women. / 2015 / PubMed / Full text
- Role of the serotonin transporter gene locus in the response to SSRI treatment of major depressive disorder in late life. / 05.2015 / PubMed / Full text
- The Impact of Genetics on Physical Resilience and Successful Aging. / 09.2015 / PubMed / Full text
- Serotonin transporter polymorphism modifies the association between depressive symptoms and sleep onset latency complaint in elderly people: results from the 'InveCe.Ab' study. / 04.2015 / PubMed / Full text
SRC[править]
- Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. / 18.08.2020 / PubMed / Full text
- Metabolic characteristics of CD8 T cell subsets in young and aged individuals are not predictive of functionality. / 05.06.2020 / PubMed / Full text
- Overexpression of steroid receptor coactivators alleviates hyperglycemia-induced endothelial cell injury in rats through activating the PI3K/Akt pathway. / 05.2019 / PubMed / Full text
- Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text
- Genetic and Environmental Models of Circadian Disruption Link SRC-2 Function to Hepatic Pathology. / 10.2016 / PubMed / Full text
- Conflict-Specific Aging Effects Mainly Manifest in Early Information Processing Stages-An ERP Study with Different Conflict Types. / 2016 / PubMed / Full text
- Investigating the stability of mcDESPOT myelin water fraction values derived using a stochastic region contraction approach. / 01.2015 / PubMed / Full text
SRM[править]
- [Geriatric specificities of localized renal cell carcinoma]. / 11.2019 / PubMed / Full text
- A targeted proteomic assay for the measurement of plasma proteoforms related to human aging phenotypes. / 08.2017 / PubMed / Full text
- The effect of tone-vocoding on spatial release from masking for old, hearing-impaired listeners. / 04.2017 / PubMed / Full text
- The role of early and late reflections on spatial release from masking: Effects of age and hearing loss. / 03.2017 / PubMed / Full text
- Cortical Measures of Binaural Processing Predict Spatial Release from Masking Performance. / 2017 / PubMed / Full text
- Release from masking for small spatial separations: Effects of age and hearing loss. / 07.2016 / PubMed / Full text
- Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes. / 01.2016 / PubMed / Full text
TAT[править]
- Screening for a suitable cell membrane anchoring tag for Pseudomonas aeruginosa and applying it in cell membrane real-time tracking to investigate membrane aging. / 08.2020 / PubMed / Full text
- Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence. / 10.2020 / PubMed / Full text
- Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides. / 2019 / PubMed / Full text
- Effects of HIV-1 gp120 and TAT-derived microvesicles on endothelial cell function. / 01.05.2019 / PubMed / Full text
- Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation. / 05.01.2017 / PubMed / Full text
- Characteristics, tissue-specific expression, and hormonal regulation of expression of tyrosine aminotransferase in the avian female reproductive tract. / 10.2016 / PubMed / Full text
- Nanog induces suppression of senescence through downregulation of p27KIP1 expression. / 01.03.2016 / PubMed / Full text
TPP1[править]
- TPP1 Enhances the Therapeutic Effects of Transplanted Aged Mesenchymal Stem Cells in Infarcted Hearts via the MRE11/AKT Pathway. / 2020 / PubMed / Full text
- FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping. / 03.11.2020 / PubMed / Full text
- Gemfibrozil, food and drug administration-approved lipid-lowering drug, increases longevity in mouse model of late infantile neuronal ceroid lipofuscinosis. / 05.2017 / PubMed / Full text
- Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease. / 01.2017 / PubMed / Full text
- Increased expression of telomere-regulating genes in endurance athletes with long leukocyte telomeres. / 15.01.2016 / PubMed / Full text
- SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin. / 2014 / PubMed / Full text
- Essential role for the TRF2 telomere protein in adult skin homeostasis. / 08.2014 / PubMed / Full text
TRIM59[править]
- DNA methylation of the ELOVL2, FHL2, KLF14, C1orf132/MIR29B2C, and TRIM59 genes for age prediction from blood, saliva, and buccal swab samples. / 01.2019 / PubMed / Full text
- Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing. / 09.2018 / PubMed / Full text
- Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text
- DNA methylation in ELOVL2 and C1orf132 correctly predicted chronological age of individuals from three disease groups. / 01.2018 / PubMed / Full text
- Independent validation of DNA-based approaches for age prediction in blood. / 07.2017 / PubMed / Full text
- Donor age and C1orf132/MIR29B2C determine age-related methylation signature of blood after allogeneic hematopoietic stem cell transplantation. / 2016 / PubMed / Full text
- Development of a forensically useful age prediction method based on DNA methylation analysis. / 07.2015 / PubMed / Full text
TSC1[править]
- [i]Tsc1[/i] Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells. / 10.09.2020 / PubMed / Full text
- mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism. / 06.2019 / PubMed / Full text
- FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling. / 25.03.2018 / PubMed / Full text
- Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. / 12.2017 / PubMed / Full text
- Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice. / 11.04.2017 / PubMed / Full text
- mTOR inactivation by ROS-JNK-p53 pathway plays an essential role in psedolaric acid B induced autophagy-dependent senescence in murine fibrosarcoma L929 cells. / 05.09.2013 / PubMed / Full text
- Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models. / 09.2013 / PubMed / Full text
UCP3[править]
- Altered miRNA and mRNA Expression in Sika Deer Skeletal Muscle with Age. / 06.02.2020 / PubMed / Full text
- Age-related sex differences in the expression of important disease-linked mitochondrial proteins in mice. / 05.12.2019 / PubMed / Full text
- Integrated study on comparative transcriptome and skeletal muscle function in aged rats. / 01.2018 / PubMed / Full text
- Pleiotropic effects of UCP2-UCP3 variability on leucocyte telomere length and glucose homeostasis. / 06.2017 / PubMed / Full text
- Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians. / 08.2016 / PubMed / Full text
- [Genotype and allele frequencies of UCP and PPAR gene families in residents of besieged Leningrad and in the control group]. / 2014 / PubMed
- Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. / 04.2014 / PubMed / Full text
XPC[править]
- MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene XPC in Age-related Cataract. / 12.10.2018 / PubMed / Full text
- Global-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo Modifiers. / 2016 / PubMed / Full text
- Xeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulation. / 02.2016 / PubMed / Full text
- Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes. / 19.10.2015 / PubMed / Full text
- [Role of DNA repair genes in radiation-induced changes of lifespan of Drosophila melanogaster]. / 09-10.2014 / PubMed
- Defective mitophagy in XPA via PARP-1 hyperactivation and NAD( )/SIRT1 reduction. / 08.05.2014 / PubMed / Full text
- Postprandial activation of p53-dependent DNA repair is modified by Mediterranean diet supplemented with coenzyme Q10 in elderly subjects. / 07.2014 / PubMed / Full text
ABCA7[править]
- New genetic players in late-onset Alzheimer's disease: Findings of genome-wide association studies. / 08.2018 / PubMed / Full text
- Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text
- Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text
- Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study. / 2017 / PubMed / Full text
- Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
- Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. / 04.2016 / PubMed / Full text
ADAM17[править]
- ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19. / 2020 / PubMed / Full text
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text
- Role of Adipose Tissue Endothelial ADAM17 in Age-Related Coronary Microvascular Dysfunction. / 06.2017 / PubMed / Full text
- Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets. / 03.2017 / PubMed / Full text
- [The effect of PNS on the content and activity of alpha-secretase in the brains of SAMP8 mice with alzheimer's disease]. / 11.2012 / PubMed
- Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. / 04-05.2013 / PubMed / Full text
AFP[править]
- Effect of Alpha-Fetoprotein on Lifespan of Old Mice. / 12.2016 / PubMed / Full text
- Correlation between vitamin D levels and apoptosis in geriatric patients infected with hepatitis C virus genotype 4. / 2016 / PubMed / Full text
- A new paradigm about HERV-K102 particle production and blocked release to explain cortisol mediated immunosenescence and age-associated risk of chronic disease. / 12.2015 / PubMed
- Are Performance Measures Necessary to Predict Loss of Independence in Elderly People? / 01.2016 / PubMed / Full text
- Proteomic biomarkers for ageing the mosquito Aedes aegypti to determine risk of pathogen transmission. / 2013 / PubMed / Full text
- Effect of vocal nerve section on song and ZENK protein expression in area X in adult male zebra finches. / 2012 / PubMed / Full text
AMT[править]
- A multi-method comparison of autobiographical memory impairments amongst younger and older adults. / 12.03.2020 / PubMed / Full text
- Autobiographical Memory From Different Life Stages in Individuals With Obstructive Sleep Apnea. / 03.2019 / PubMed / Full text
- Fatigue in Younger and Older Drivers: Effectiveness of an Alertness-Maintaining Task. / 09.2017 / PubMed / Full text
- Reduced specificity and enhanced subjective experience of future thinking in ageing: the influence of avoidance and emotion-regulation strategies. / 01.2018 / PubMed / Full text
- Evaluation of delirium screening tools in geriatric medical inpatients: a diagnostic test accuracy study. / 11.2016 / PubMed / Full text
- Falls and other geriatric syndromes in Blantyre, Malawi: a community survey of older adults. / 12.2014 / PubMed / Full text
AQP1[править]
- Blue Light Induces Down-Regulation of Aquaporin 1, 3, and 9 in Human Keratinocytes. / 03.11.2018 / PubMed / Full text
- [Age-related changes of water transport by corneal endothelial cells in rats.] / 2017 / PubMed
- Investigation of the effects of aging on the expression of aquaporin 1 and aquaporin 4 protein in heart tissue. / 01.2017 / PubMed / Full text
- Seasonal and Ageing-Depending Changes of Aquaporins 1 and 9 Expression in the Genital Tract of Buffalo Bulls (Bubalus bubalis). / 08.2016 / PubMed / Full text
- Investigation of age-related changes in the expression of aquaporin-1 and aquaporin-5 in the salivary glands of mice. / 09.2016 / PubMed / Full text
- The effects of high doses of nandrolone decanoate and exercise on prostate microvasculature of adult and older rats. / 15.01.2015 / PubMed / Full text
ASPA[править]
- Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. / 04.2018 / PubMed / Full text
- Development of a methylation marker set for forensic age estimation using analysis of public methylation data and the Agena Bioscience EpiTYPER system. / 09.2016 / PubMed / Full text
- Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures. / 05.2016 / PubMed / Full text
- Plasma Amyloid Beta 1-42 and DNA Methylation Pattern Predict Accelerated Aging in Young Subjects with Down Syndrome. / 12.2016 / PubMed / Full text
- Developing a DNA methylation assay for human age prediction in blood and bloodstain. / 07.2015 / PubMed / Full text
- Aging of blood can be tracked by DNA methylation changes at just three CpG sites. / 03.02.2014 / PubMed / Full text
BID[править]
- Dabigatran etexilate: appropriate use in patients with chronic kidney disease and in the elderly patients. / 06.2017 / PubMed / Full text
- Sperm-associated antigen 9 (SPAG9) promotes the survival and tumor growth of triple-negative breast cancer cells. / 10.2016 / PubMed / Full text
- Rationale for the Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects Trial (POST5). / 04.2016 / PubMed / Full text
- The geriatric mania asenapine study (GeMS). / 05-06.2016 / PubMed / Full text
- The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats. / 07.2015 / PubMed / Full text
- Neuroimmunomodulation and aging: a role for transferrin and the hypothalamus/thymus axis. / 02.2013 / PubMed / Full text
BMF[править]
- Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. / 13.01.2020 / PubMed / Full text
- lncRNA-ES3/miR-34c-5p/BMF axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs. / 17.01.2019 / PubMed / Full text
- Aging, hematopoiesis, and the myelodysplastic syndromes. / 08.12.2017 / PubMed / Full text
- Bone marrow fat unsaturation in young adults is not affected by present or childhood obesity, but increases with age: A pilot study. / 11.2015 / PubMed / Full text
- Loss of the proapoptotic BH3-only protein BCL-2 modifying factor prolongs the fertile life span in female mice. / 04.2014 / PubMed / Full text
- Comparison of vertebral bone marrow fat assessed by 1H MRS and inphase and out-of-phase MRI among family members. / 02.2014 / PubMed / Full text
BMP15[править]
- Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-KIT. / 04.2020 / PubMed / Full text
- Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival. / 12.2019 / PubMed / Full text
- Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. / 01.2019 / PubMed / Full text
- Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. / 18.10.2017 / PubMed / Full text
- Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. / 07.2015 / PubMed / Full text
- Interactions between genetic variants in AMH and [[AMHR2]] may modify age at natural menopause. / 2013 / PubMed / Full text
BRD4[править]
- Inhibition of BRD4 triggers cellular senescence through suppressing aurora kinases in oesophageal cancer cells. / 20.09.2020 / PubMed / Full text
- BRD4 contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake. / 11.05.2020 / PubMed / Full text
- BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes. / 26.09.2019 / PubMed / Full text
- Interference with the bromodomain epigenome readers drives p21 expression and tumor senescence. / 01.10.2019 / PubMed / Full text
- Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. / 07.2019 / PubMed / Full text
- Bromodomain and Extraterminal Protein Inhibition Blocks Growth of Triple-negative Breast Cancers through the Suppression of Aurora Kinases. / 04.11.2016 / PubMed / Full text
CCR6[править]
- Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells. / 07.2019 / PubMed / Full text
- Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text
- Circulating T helper and T regulatory subsets in untreated early rheumatoid arthritis and healthy control subjects. / 10.2016 / PubMed / Full text
- Double negative (IgG IgD-CD27-) B cells are increased in a cohort of moderate-severe Alzheimer's disease patients and show a pro-inflammatory trafficking receptor phenotype. / 2015 / PubMed / Full text
- Trafficking phenotype and production of granzyme B by double negative B cells (IgG( )IgD(-)CD27(-)) in the elderly. / 06.2014 / PubMed / Full text
- Increased Th17 differentiation in aged mice is significantly associated with high IL-1β level and low IL-2 expression. / 01.2014 / PubMed / Full text
CD74[править]
- Identification of a conserved gene signature associated with an exacerbated inflammatory environment in the hippocampus of aging rats. / 04.2017 / PubMed / Full text
- Intramembrane proteolysis within lysosomes. / 12.2016 / PubMed / Full text
- Proton irradiation impacts age-driven modulations of cancer progression influenced by immune system transcriptome modifications from splenic tissue. / 09.2015 / PubMed / Full text
- Macrophage migration inhibitory factor confers resistance to senescence through CD74-dependent AMPK-FOXO3a signaling in mesenchymal stem cells. / 22.04.2015 / PubMed / Full text
- Macrophage migration inhibitory factor deficiency in chronic obstructive pulmonary disease. / 15.03.2014 / PubMed / Full text
- Effects of minocycline on spatial learning, hippocampal neurogenesis and microglia in aged and adult mice. / 01.04.2013 / PubMed / Full text
CDC42[править]
- Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1. / 05.09.2019 / PubMed / Full text
- Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies. / 20.10.2018 / PubMed / Full text
- The relationship between reproductive and biochemical ageing at the time of the menopausal transition. / 11.2017 / PubMed / Full text
- Senescent cells communicate via intercellular protein transfer. / 15.04.2015 / PubMed / Full text
- A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis. / 2014 / PubMed / Full text
- LOX-1 in the maintenance of cytoskeleton and proliferation in senescent cardiac fibroblasts. / 07.2013 / PubMed / Full text
CTNNB1[править]
- Catalog of Lung Cancer Gene Mutations Among Chinese Patients. / 2020 / PubMed / Full text
- [i]TP53[/i] Tumor-suppressor Gene Plays a Key Role in IGF1 Signaling Pathway Related to the Aging of Human Melanocytes. / 05.2019 / PubMed / Full text
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
- Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
- P4 medicine and osteoporosis: a systematic review. / 12.2016 / PubMed / Full text
- Expression profile analysis of new candidate genes for the therapy of primary osteoporosis. / 2016 / PubMed
CYP11A1[править]
- Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice. / 15.04.2019 / PubMed / Full text
- Morphological rearrangement of the cortical region, in aging ovaries. / 07.2019 / PubMed / Full text
- Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice. / 01.08.2018 / PubMed / Full text
- Systemic analysis of gene expression profiles in porcine granulosa cells during aging. / 14.11.2017 / PubMed / Full text
- Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). / 03.2018 / PubMed / Full text
- Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs. / 01.03.2017 / PubMed / Full text
CYP17A1[править]
- Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼. / 11.2020 / PubMed / Full text
- Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). / 03.2018 / PubMed / Full text
- Testicular gene expression of steroidogenesis-related factors in prepubertal, postpubertal, and aging dogs. / 01.03.2017 / PubMed / Full text
- CYP17A1 Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study. / 04.2016 / PubMed / Full text
- Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. / 2014 / PubMed / Full text
- Of mice and men--warning: intact versus castrated adult male mice as xenograft hosts are equivalent to hypogonadal versus abiraterone treated aging human males, respectively. / 09.2013 / PubMed / Full text
DKK1[править]
- Low Serum Levels of DKK2 Predict Incident Low-Impact Fracture in Older Women. / 07.2019 / PubMed / Full text
- Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling. / 11.06.2019 / PubMed / Full text
- [Role and alterations of DNA methylation during the aging and cancer]. / 01.2018 / PubMed / Full text
- Melatonin regulates the aging mouse hippocampal homeostasis via the sirtuin1-FOXO1 pathway. / 2017 / PubMed / Full text
- Circulating sclerostin and dickkopf-1 levels in ossification of the posterior longitudinal ligament of the spine. / 05.2016 / PubMed / Full text
- Vaccination with DKK1-derived peptides promotes bone formation and bone mass in an aged mouse osteoporosis model. / 08.2014 / PubMed / Full text
FGF19[править]
- Bile acid receptor agonists in primary biliary cholangitis: Regulation of the cholangiocyte secretome and downstream T cell differentiation. / 05.2019 / PubMed / Full text
- Kotho and aging. / 09.2016 / PubMed
- The Klotho proteins in health and disease. / 01.2019 / PubMed / Full text
- Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging. / 2018 / PubMed / Full text
- A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion. / 08.11.2016 / PubMed / Full text
- A preliminary candidate approach identifies the combination of chemerin, fetuin-A, and fibroblast growth factors 19 and 21 as a potential biomarker panel of successful aging. / 06.2015 / PubMed / Full text
GCLM[править]
- Silencing Bach1 alters aging-related changes in the expression of Nrf2-regulated genes in primary human bronchial epithelial cells. / 15.09.2019 / PubMed / Full text
- Ontogeny and aging of Nrf2 pathway genes in livers of rats. / 15.06.2018 / PubMed / Full text
- Sulfur amino acid restriction-induced changes in redox-sensitive proteins are associated with slow protein synthesis rates. / 04.2018 / PubMed / Full text
- Aging-related decline in the induction of Nrf2-regulated antioxidant genes in human bronchial epithelial cells. / 04.2018 / PubMed / Full text
- Nrf2 signaling is impaired in the aging RPE given an oxidative insult. / 02.2014 / PubMed / Full text
- Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction. / 2013 / PubMed / Full text
GEM[править]
- The Impact of Geriatric Emergency Management Nurses on the Care of Frail Older Patients in the Emergency Department: a Systematic Review. / 09.2020 / PubMed / Full text
- Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. / 09.2019 / PubMed / Full text
- Understanding of diagnosis and medications among non-English-speaking older patients. / 06.2018 / PubMed / Full text
- Increased gait variability may not imply impaired stride-to-stride control of walking in healthy older adults: Winner: 2013 Gait and Clinical Movement Analysis Society Best Paper Award. / 06.2017 / PubMed / Full text
- The development and evaluation of mini-GEMs - short, focused, online e-learning videos in geriatric medicine. / 04-06.2018 / PubMed / Full text
- Neoplastic and nonneoplastic lesions in aging mice of unique and common inbred strains contribution to modeling of human neoplastic diseases. / 05.2014 / PubMed / Full text
GLS[править]
- Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography. / 15.07.2018 / PubMed / Full text
- Future Perspectives for Management of Stage A Heart Failure. / 01.07.2018 / PubMed / Full text
- Reference Ranges of Left Ventricular Strain Measures by Two-Dimensional Speckle-Tracking Echocardiography in Children: A Systematic Review and Meta-Analysis. / 03.2016 / PubMed / Full text
- Cardiorespiratory fitness modifies the relationship between myocardial function and cerebral blood flow in older adults. / 01.05.2016 / PubMed / Full text
- Left ventricular strain examination of different aged adults with 3D speckle tracking echocardiography. / 03.2014 / PubMed / Full text
- Left ventricular three-dimensional global systolic strain by real-time three-dimensional speckle-tracking in children: feasibility, reproducibility, maturational changes, and normal ranges. / 08.2013 / PubMed / Full text
GSTP1[править]
- DCAF1 regulates Treg senescence via the ROS axis during immunological aging. / 02.11.2020 / PubMed / Full text
- Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text
- Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. / 2016 / PubMed / Full text
- Contribution of genetic polymorphisms on functional status at very old age: a gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway. / 04.2014 / PubMed / Full text
- Epigenetic susceptibility factors for prostate cancer with aging. / 12.2013 / PubMed / Full text
- The age-related change of glutathione antioxidant system in mice liver. / 07.2013 / PubMed / Full text
HAL[править]
- Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population. / 06-09.2018 / PubMed / Full text
- Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats. / 06.2019 / PubMed / Full text
- Histone deacetylase inhibitors reverse age-related increases in side effects of haloperidol in mice. / 08.2017 / PubMed / Full text
- Differential effects of intermittent versus continuous haloperidol treatment throughout adolescence on haloperidol sensitization and social behavior in adulthood. / 03.10.2014 / PubMed / Full text
- HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation. / 05.2014 / PubMed / Full text
- Selective matrix (hyaluronan) interaction with CD44 and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction. / 10.2013 / PubMed / Full text
HBP1[править]
- Suppression of p38/HBP1 pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence. / 03-04.2020 / PubMed / Full text
- Transcription factor HBP1: A regulator of senescence and apoptosis of preadipocytes. / 17.09.2019 / PubMed / Full text
- A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis. / 19.05.2017 / PubMed / Full text
- Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve. / 10.2016 / PubMed / Full text
- HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis. / 10.06.2016 / PubMed / Full text
- Absence of AMPKα2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts. / 02.2016 / PubMed / Full text
HCN1[править]
- Protein expression changes of HCN1 and HCN2 in hippocampal subregions of gerbils during the normal aging process. / 11.2019 / PubMed / Full text
- HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation. / 15.02.2019 / PubMed / Full text
- Dopaminergic Neurons Exhibit an Age-Dependent Decline in Electrophysiological Parameters in the MitoPark Mouse Model of Parkinson's Disease. / 06.04.2016 / PubMed / Full text
- Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes. / 11.11.2015 / PubMed / Full text
- Age-associated expression of HCN channel isoforms in rat sinoatrial node. / 02.2016 / PubMed / Full text
- Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. / 27.02.2015 / PubMed / Full text
HDAC6[править]
- Inhibition of HDAC6 Attenuates Diabetes-Induced Retinal Redox Imbalance and Microangiopathy. / 09.07.2020 / PubMed / Full text
- Cellular senescence is associated with reorganization of the microtubule cytoskeleton. / 03.2019 / PubMed / Full text
- 2,4‑Di‑tert‑butylphenol, a potential HDAC6 inhibitor, induces senescence and mitotic catastrophe in human gastric adenocarcinoma AGS cells. / 05.2018 / PubMed / Full text
- HDAC6 Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of PLIN2 in Drosophila. / 09.10.2017 / PubMed / Full text
- The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology. / 29.08.2017 / PubMed / Full text
- Declined Expression of Histone Deacetylase 6 Contributes to Periodontal Ligament Stem Cell Aging. / 01.2017 / PubMed / Full text
HMGA2[править]
- 4D Genome Rewiring during Oncogene-Induced and Replicative Senescence. / 07.05.2020 / PubMed / Full text
- The protective effects of HMGA2 in the senescence process of bone marrow-derived mesenchymal stromal cells. / 04.2020 / PubMed / Full text
- Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. / 05.11.2018 / PubMed / Full text
- Molecular differences between stromal cell populations from deciduous and permanent human teeth. / 18.04.2015 / PubMed / Full text
- Rb protein is essential to the senescence-associated heterochromatic foci formation induced by HMGA2 in primary WI38 cells. / 20.08.2013 / PubMed / Full text
- MYCN/LIN28B/Let-7/HMGA2 pathway implicated by meta-analysis of GWAS in suppression of post-natal proliferation thereby potentially contributing to aging. / 07-08.2013 / PubMed / Full text
HMGB2[править]
- Loss of Endogenous HMGB2 Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice. / 25.01.2019 / PubMed / Full text
- HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types. / 17.05.2018 / PubMed / Full text
- Correlations between age, functional status, and the senescence-associated proteins HMGB2 and p16 . / 04.2018 / PubMed / Full text
- Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence. / 30.04.2018 / PubMed / Full text
- Loss of Endometrial Plasticity in Recurrent Pregnancy Loss. / 02.2016 / PubMed / Full text
- Quantitative proteomic profiling of tumor cell response to telomere dysfunction using isotope-coded protein labeling (ICPL) reveals interaction network of candidate senescence markers. / 08.10.2013 / PubMed / Full text
IGF2[править]
- Paternal Insulin-like Growth Factor 2 (Igf2) Regulates Stem Cell Activity During Adulthood. / 02.2017 / PubMed / Full text
- Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing. / 09.2016 / PubMed / Full text
- Autocrine Action of IGF2 Regulates Adult β-Cell Mass and Function. / 12.2015 / PubMed / Full text
- Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex. / 07.07.2015 / PubMed / Full text
- miR-30e targets IGF2-regulated osteogenesis in bone marrow-derived mesenchymal stem cells, aortic smooth muscle cells, and ApoE-/- mice. / 01.04.2015 / PubMed / Full text
- Epigenetic susceptibility factors for prostate cancer with aging. / 12.2013 / PubMed / Full text
IL4[править]
- Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia. / 01.01.2018 / PubMed / Full text
- Aging Affects Bone Marrow Macrophage Polarization: Relevance to Bone Healing. / 06.2016 / PubMed / Full text
- IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain. / 18.10.2016 / PubMed / Full text
- IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis. / 11.08.2015 / PubMed / Full text
- LIPID PROFILE AND CYTOKINES INTERACTIONS DURING SUCCESSFUL AGING. / 06.2015 / PubMed
- Ageing related periostin expression increase from cardiac fibroblasts promotes cardiomyocytes senescent. / 26.09.2014 / PubMed / Full text
IRF8[править]
- Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2. / 2020 / PubMed / Full text
- Hyperglycemia-induced inflamm-aging accelerates gingival senescence via NLRC4 phosphorylation. / 06.12.2019 / PubMed / Full text
- IRF8 induces senescence of lung cancer cells to exert its tumor suppressive function. / 12.2019 / PubMed / Full text
- Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
- Aging impairs both primary and secondary RIG-I signaling for interferon induction in human monocytes. / 12.12.2017 / PubMed / Full text
- Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex. / 08.2015 / PubMed / Full text
JAK1[править]
- Implication of JAK1/STAT3/SOCS3 Pathway in Aging of Cerebellum of Male Rat: Histological and Molecular study. / 01.06.2020 / PubMed / Full text
- Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling. / 01.05.2020 / PubMed / Full text
- The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Through JAK1. / 2019 / PubMed / Full text
- Influence of age and renal impairment on the steady state pharmacokinetics of filgotinib, a selective JAK1 inhibitor. / 12.2018 / PubMed / Full text
- Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. / 04.2018 / PubMed / Full text
- Interferon-γ induces senescence in normal human melanocytes. / 2014 / PubMed / Full text
KIT[править]
- Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-KIT. / 04.2020 / PubMed / Full text
- miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. / 06.2018 / PubMed / Full text
- Comparison of Changes in the Interstitial Cells of Cajal and Neuronal Nitric Oxide Synthase-positive Neuronal Cells With Aging Between the Ascending and Descending Colon of F344 Rats. / 30.10.2017 / PubMed / Full text
- Leukocyte telomere length in mastocytosis: correlations with depression and perceived stress. / 01.2014 / PubMed / Full text
- Changes of number of cells expressing proliferation and progenitor cell markers with age in rabbit intervertebral discs. / 05.2013 / PubMed / Full text
- Systemic mastocytosis in the elderly. / 05.2013 / PubMed / Full text
LAMP2[править]
- An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into RPE Stress Associated with Retinopathy. / 11.09.2020 / PubMed / Full text
- Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells. / 01.04.2020 / PubMed / Full text
- Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina. / 19.11.2019 / PubMed / Full text
- SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence. / 06.2020 / PubMed / Full text
- A pH probe inhibits senescence in mesenchymal stem cells. / 07.12.2018 / PubMed / Full text
- Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. / 02.2018 / PubMed / Full text
MAPK1[править]
- Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1. / 2020 / PubMed / Full text
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
- Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text
- iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation. / 01.10.2017 / PubMed / Full text
- Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging. / 01.07.2017 / PubMed / Full text
- Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence. / 2015 / PubMed / Full text
MCU[править]
- A rare case of Epstein-Barr virus-positive mucocutaneous ulcer that developed into an intestinal obstruction: a case report. / 13.01.2020 / PubMed / Full text
- Inhibition of Mitochondrial Calcium Overload by SIRT3 Prevents Obesity- or Age-Related Whitening of Brown Adipose Tissue. / 02.2020 / PubMed / Full text
- Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. / 09.2019 / PubMed / Full text
- The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling. / 12.2018 / PubMed / Full text
- Physical exercise in aging human skeletal muscle increases mitochondrial calcium uniporter expression levels and affects mitochondria dynamics. / 12.2016 / PubMed / Full text
- Evolution of increased adult longevity in Drosophila melanogaster populations selected for adaptation to larval crowding. / 02.2016 / PubMed / Full text
MEF2C[править]
- Decline in cellular function of aged mouse c-kit cardiac progenitor cells. / 01.10.2017 / PubMed / Full text
- Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
- Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. / 01.12.2016 / PubMed / Full text
- Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy. / 03.2017 / PubMed / Full text
- Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. / 04.2016 / PubMed / Full text
- Postnatal expression patterns and polymorphism analysis of the bovine myocyte enhancer factor 2C (Mef2C) gene. / 12.2014 / PubMed / Full text
MME[править]
- Geriatric Opioid Harm Reduction: Interprofessional Student Learning Outcomes. / 01-12.2020 / PubMed / Full text
- Effectiveness of local anesthetic injection in geriatric patients following operative management of proximal and diaphyseal femur fracture. / 11.2019 / PubMed / Full text
- Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic PIK3CA accompanied with pro-tumorigenic secretome. / 01.08.2019 / PubMed / Full text
- Medial meniscus extrusion increases with age and BMI and is depending on different loading conditions. / 08.2018 / PubMed / Full text
- Rare Variants in MME, Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies. / 01.09.2016 / PubMed / Full text
- Genetic analysis of mesangial matrix expansion in aging mice and identification of Far2 as a candidate gene. / 12.2013 / PubMed / Full text
MVD[править]
- Young and elderly oral squamous cell carcinoma patients present similar angiogenic profile and predominance of M2 macrophages: Comparative immunohistochemical study. / 12.2019 / PubMed / Full text
- Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density. / 12.2018 / PubMed / Full text
- Assessing Microvascular Function in Humans from a Chronic Disease Perspective. / 12.2017 / PubMed / Full text
- Changes in pro-inflammatory markers and leucine concentrations in response to Nordic Walking training combined with vitamin D supplementation in elderly women. / 08.2017 / PubMed / Full text
- Diffusion-weighted multiparametric MRI for monitoring longitudinal changes of parameters in rabbit VX2 liver tumors. / 09.2016 / PubMed / Full text
- [Expression of vascular endothelial growth factor and microvessel density in different brain regions in aged rats]. / 07.2014 / PubMed / Full text
NDUFB8[править]
- Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature. / 15.04.2020 / PubMed / Full text
- Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. / 12.02.2020 / PubMed / Full text
- Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. / 23.05.2018 / PubMed / Full text
- Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions. / 06.2018 / PubMed / Full text
- Resveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway. / 04.2017 / PubMed / Full text
- Reduced levels of mitochondrial complex I subunit NDUFB8 and linked complex I III oxidoreductase activity in the TgCRND8 mouse model of Alzheimer's disease. / 2014 / PubMed / Full text
NF1[править]
- Conditional reprograming culture conditions facilitate growth of lower grade glioma models. / 01.12.2020 / PubMed / Full text
- Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice. / 20.12.2019 / PubMed / Full text
- NF1 loss induces senescence during human melanocyte differentiation in an iPSC-based model. / 07.2015 / PubMed / Full text
- TGF-β/NF1/Smad4-mediated suppression of ANT2 contributes to oxidative stress in cellular senescence. / 12.2014 / PubMed / Full text
- Neuropsychological impairments in elderly Neurofibromatosis type 1 patients. / 04.2014 / PubMed / Full text
- Long-term prognosis of patients with pediatric pheochromocytoma. / 02.2014 / PubMed / Full text
NOS3[править]
- Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation. / 22.05.2020 / PubMed / Full text
- Hypertension and longevity: role of genetic polymorphisms in renin-angiotensin-aldosterone system and endothelial nitric oxide synthase. / 05.2019 / PubMed / Full text
- NOS3 Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels. / 11.07.2018 / PubMed / Full text
- Vascular senescence and ageing: a role for the MEOX proteins in promoting endothelial dysfunction. / 10.2017 / PubMed / Full text
- Fetal programming of blood pressure in a transgenic mouse model of altered intrauterine environment. / 01.12.2016 / PubMed / Full text
- Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans. / 04.2013 / PubMed / Full text
NPR1[править]
- The NPR1-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana. / 03.12.2020 / PubMed / Full text
- Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis. / 07.2020 / PubMed / Full text
- Some things get better with age: differences in salicylic acid accumulation and defense signaling in young and mature Arabidopsis. / 2014 / PubMed / Full text
- Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid. / 12.2014 / PubMed / Full text
- Autophagy deficiency leads to accumulation of ubiquitinated proteins, ER stress, and cell death in Arabidopsis. / 09.2014 / PubMed / Full text
- A dissection of the effects of ethylene, H2O2 and high irradiance on antioxidants and several genes associated with stress and senescence in tobacco leaves. / 15.02.2014 / PubMed / Full text
NRK[править]
- [Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/ULK1 signaling activation]. / 03.2019 / PubMed / Full text
- Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy. / 24.12.2018 / PubMed / Full text
- Fascin2 regulates cisplatin-induced apoptosis in NRK-52E cells. / 15.01.2017 / PubMed / Full text
- 2,3,5,4'-Tetrahydroxystilbene-2-O-[i]β[/i]-D-glucoside Promotes Expression of the Longevity Gene Klotho. / 2016 / PubMed / Full text
- A role for the age-dependent loss of α(E)-catenin in regulation of N-cadherin expression and cell migration. / 01.06.2014 / PubMed / Full text
- Overexpression of MMP-7 Increases Collagen 1A2 in the Aging Kidney. / 10.2013 / PubMed / Full text
PAK1[править]
- 1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating PAK1 at nM levels. / 2018 / PubMed / Full text
- From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic PAK1-blockers/longevity-promoters for cancer therapy. / 15.12.2017 / PubMed / Full text
- Effect of Okinawa Propolis on PAK1 Activity, Caenorhabditis elegans Longevity, Melanogenesis, and Growth of Cancer Cells. / 13.07.2016 / PubMed / Full text
- Several herbal compounds in Okinawa plants directly inhibit the oncogenic/aging kinase PAK1. / 12.2014 / PubMed / Full text
- Herbal therapeutics that block the oncogenic kinase PAK1: a practical approach towards PAK1-dependent diseases and longevity. / 05.2014 / PubMed / Full text
- PAK1-deficiency/down-regulation reduces brood size, activates HSP16.2 gene and extends lifespan in Caenorhabditis elegans. / 02.2013 / PubMed / Full text
PGP[править]
- Age-associated changes of the intrinsic nervous system in relation with interstitial cells in the pre-weaning goat rumen. / 14.07.2019 / PubMed / Full text
- Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats. / 2017 / PubMed / Full text
- Change in the Interstitial Cells of Cajal and nNOS Positive Neuronal Cells with Aging in the Stomach of F344 Rats. / 2017 / PubMed / Full text
- The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via CXCR1-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs. / 01.2017 / PubMed / Full text
- [CHANGES IN THE PANCREATIC ISLETS AND NERVOUS ELEMENTS IN RATS DURING AGING (AN IMMUNOHISTOCHEMICAL STUDY)]. / 2015 / PubMed
- Associations between xerostomia, histopathological alterations, and autonomic innervation of labial salivary glands in men in late midlife. / 09.2014 / PubMed / Full text
POR[править]
- The Ventricular System Enlarges Abnormally in the Seventies, Earlier in Men, and First in the Frontal Horn: A Study Based on More Than 3,000 Scans. / 2019 / PubMed / Full text
- Clinical findings associated with development of postoperative reflux and short-term survival after small intestinal surgery in geriatric and mature nongeriatric horses. / 07.2019 / PubMed / Full text
- Effect of Age and Allele Variants of CYP3A5, CYP3A4, and POR Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. / 12.2017 / PubMed / Full text
- Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis. / 01.05.2017 / PubMed / Full text
- Endometriosis has no negative impact on outcomes of in vitro fertilisation in women with poor ovarian response. / 09.2016 / PubMed / Full text
- Short-term complications after colic surgery in geriatric versus mature non-geriatric horses. / 02.2015 / PubMed / Full text
POT1[править]
- Decreased expression of TERT and telomeric proteins as human ovaries age may cause telomere shortening. / 27.08.2020 / PubMed / Full text
- MiR-185 targets POT1 to induce telomere dysfunction and cellular senescence. / 18.07.2020 / PubMed / Full text
- Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text
- Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence. / 2019 / PubMed / Full text
- A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region. / 03.11.2015 / PubMed / Full text
- Caenorhabditis elegans POT-1 and POT-2 repress telomere maintenance pathways. / 02.2013 / PubMed / Full text
PRC1[править]
- Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text
- Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein BMI1 in breast cancer cells. / 07.2018 / PubMed / Full text
- Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster. / 02.2018 / PubMed / Full text
- The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging. / 2016 / PubMed / Full text
- CBX7 and miR-9 are part of an autoregulatory loop controlling p16(INK) (4a). / 12.2015 / PubMed / Full text
- Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7. / 20.12.2013 / PubMed / Full text
PROC[править]
- Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation. / 15.04.2020 / PubMed / Full text
- Effects of feeding frequency of an elevated plane of milk replacer and calf age on behavior, and glucose and insulin kinetics in male Holstein calves. / 07.2019 / PubMed / Full text
- Age-related effects on markers of inflammation and cartilage metabolism in response to an intra-articular lipopolysaccharide challenge in horses. / 02.2017 / PubMed / Full text
- Normative data for rotational chair stratified by age. / 02.2016 / PubMed / Full text
- Day-to-Day Impact of Vaginal Aging questionnaire: a multidimensional measure of the impact of vaginal symptoms on functioning and well-being in postmenopausal women. / 02.2015 / PubMed / Full text
- Growth and feed conversion efficiency of Dorper and Rambouillet lambs. / 10.2013 / PubMed / Full text
PTGS2[править]
- Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. / 03.2020 / PubMed / Full text
- Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. / 21.05.2019 / PubMed / Full text
- Analysis of molecular networks and targets mining of Chinese herbal medicines on anti-aging. / 28.12.2016 / PubMed / Full text
- Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging. / 2014 / PubMed / Full text
- Coordination of gene expression of arachidonic and docosahexaenoic acid cascade enzymes during human brain development and aging. / 2014 / PubMed / Full text
- Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer's disease animal model. / 2013 / PubMed / Full text
PTX3[править]
- Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. / 27.01.2020 / PubMed / Full text
- Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study. / 13.07.2020 / PubMed / Full text
- Changes in Proteomic Profiles are Related to Changes in BMI and Fat Distribution During 10 Years of Aging. / 01.2020 / PubMed / Full text
- Inflammatory Long Pentraxin 3 is Associated with Leukocyte Telomere Length in Night-Shift Workers. / 2017 / PubMed / Full text
- Age-dependent cellular reactions of the human immune system of humanized NOD scid gamma mice on LPS stimulus. / 04.2017 / PubMed / Full text
- Elevated pentraxin 3 level at the early stage of exercise training is associated with reduction of arterial stiffness in middle-aged and older adults. / 09.2016 / PubMed / Full text
RB1[править]
- Expression of p16 in nodular fasciitis: an implication for self-limited and inflammatory nature of the lesion. / 2019 / PubMed / Full text
- G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
- Mesenchymal stromal cells having inactivated RB1 survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy. / 02.2017 / PubMed / Full text
- Suppression of RAD21 Induces Senescence of MDA-MB-231 Human Breast Cancer Cells Through RB1 Pathway Activation Via c-Myc Downregulation. / 06.2016 / PubMed / Full text
- RB1-mediated cell-autonomous and host-dependent oncosuppressor mechanisms in radiation-induced osteosarcoma. / 01.01.2014 / PubMed / Full text
- Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging. / 08.2013 / PubMed / Full text
RIG[править]
- Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling. / 2017 / PubMed / Full text
- Aging impairs both primary and secondary RIG-I signaling for interferon induction in human monocytes. / 12.12.2017 / PubMed / Full text
- Random Item Generation Is Affected by Age. / 01.10.2016 / PubMed / Full text
- Aging-related renal injury and inflammation are associated with downregulation of Klotho and induction of RIG-I/NF-κB signaling pathway in senescence-accelerated mice. / 02.2016 / PubMed / Full text
- Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors. / 06.2015 / PubMed / Full text
- Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children. / 01.02.2014 / PubMed / Full text
RIPK1[править]
- Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. / 18.11.2020 / PubMed / Full text
- Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. / 05.2020 / PubMed / Full text
- RIP kinases as modulators of inflammation and immunity. / 09.2018 / PubMed / Full text
- TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. / 06.09.2018 / PubMed / Full text
- Necroptosis increases with age and is reduced by dietary restriction. / 08.2018 / PubMed / Full text
- RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system. / 15.08.2017 / PubMed / Full text
S100A8[править]
- Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice. / 15.12.2019 / PubMed / Full text
- S100A8, which increases with age, induces cellular senescence-like changes in bovine oviduct epithelial cells. / 09.2019 / PubMed / Full text
- Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model. / 06.07.2018 / PubMed / Full text
- Lung cellular senescence is independent of aging in a mouse model of COPD/emphysema. / 13.06.2018 / PubMed / Full text
- Age-dependent changes in inflammation and extracellular matrix in bovine oviduct epithelial cells during the post-ovulatory phase. / 09.2016 / PubMed / Full text
- A transcriptional roadmap to the senescence and differentiation of human oral keratinocytes. / 01.2015 / PubMed / Full text
SERPINE1[править]
- Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. / 2020 / PubMed / Full text
- p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. / 06.2020 / PubMed / Full text
- Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes. / 15.01.2020 / PubMed / Full text
- Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. / 03.2020 / PubMed / Full text
- Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text
- A null mutation in [i]SERPINE1[/i] protects against biological aging in humans. / 11.2017 / PubMed / Full text
SHH[править]
- Recent advances in SHH medulloblastoma progression: tumor suppressor mechanisms and the tumor microenvironment. / 2019 / PubMed / Full text
- An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through SERPINB2. / 03.07.2019 / PubMed / Full text
- Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text
- Evasion of cell senescence in SHH medulloblastoma. / 17.08.2016 / PubMed / Full text
- Expression and Role of Sonic Hedgehog in the Process of Fracture Healing with Aging. / 03-04.2016 / PubMed
- The Subjective Health Horizon Questionnaire (SHH-Q): Assessing Future Time Perspectives for Facets of an Active Lifestyle. / 2016 / PubMed / Full text
SNAP25[править]
- The Biological Foundations of Sarcopenia: Established and Promising Markers. / 2019 / PubMed / Full text
- Contribution of adenosine and ATP to the carotid body chemosensory activity in ageing. / 10.2019 / PubMed / Full text
- Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age. / 06.2018 / PubMed / Full text
- NUPR1 maintains autolysosomal efflux by activating SNAP25 transcription in cancer cells. / 2018 / PubMed / Full text
- Global hypoxia induced impairment in learning and spatial memory is associated with precocious hippocampal aging. / 09.2016 / PubMed / Full text
- NOS1 and SNAP25 polymorphisms are associated with Attention-Deficit/Hyperactivity Disorder symptoms in adults but not in children. / 04.2016 / PubMed / Full text
SOST[править]
- Remodeling process in bone of aged rats in response to resistance training. / 01.09.2020 / PubMed / Full text
- Low Serum Levels of DKK2 Predict Incident Low-Impact Fracture in Older Women. / 07.2019 / PubMed / Full text
- Bone adaptation in response to treadmill exercise in young and adult mice. / 06.2018 / PubMed / Full text
- WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling. / 29.05.2015 / PubMed / Full text
- Relative influence of heritability, environment and genetics on serum sclerostin. / 03.2014 / PubMed / Full text
- Novel sandwich ELISAs for rat DMP1: age-related decrease of circulatory DMP1 levels in male rats. / 12.2013 / PubMed / Full text
SPR[править]
- Regulation of lifespan by neural excitation and REST. / 10.2019 / PubMed / Full text
- How many geriatricians should, at minimum, be staffing health regions in Australia? / 03.2018 / PubMed / Full text
- Mutation of C. elegans demethylase spr-5 extends transgenerational longevity. / 02.2016 / PubMed / Full text
- REST and stress resistance in ageing and Alzheimer's disease. / 27.03.2014 / PubMed / Full text
- H3K4 demethylase activities repress proliferative and postmitotic aging. / 04.2014 / PubMed / Full text
- Increase in tetrahydrobiopterin concentration with aging in the cerebral cortex of the senescence-accelerated mouse prone 10 strain caused by abnormal regulation of tetrahydrobiopterin biosynthesis. / 10.2013 / PubMed / Full text
TBP[править]
- Identification of reference genes for RT-qPCR data normalisation in aging studies. / 27.09.2019 / PubMed / Full text
- Trinucleotide repeat expansion of TATA-binding protein gene associated with Parkinson's disease: A Thai multicenter study. / 07.2016 / PubMed / Full text
- CALHM1 Deletion in Mice Affects Glossopharyngeal Taste Responses, Food Intake, Body Weight, and Life Span. / 07.2015 / PubMed / Full text
- Deactivation of TBP contributes to SCA17 pathogenesis. / 20.12.2014 / PubMed / Full text
- Age-dependent decrease in chaperone activity impairs MANF expression, leading to Purkinje cell degeneration in inducible SCA17 mice. / 22.01.2014 / PubMed / Full text
- [Age estimation using content of sjTREC in human peripheral blood]. / 08.2013 / PubMed
TCF7L2[править]
- A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder. / 03.2020 / PubMed / Full text
- The dynamic methylome of islets in health and disease. / 09.2019 / PubMed / Full text
- Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle. / 01.03.2019 / PubMed / Full text
- TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2. / 03.05.2017 / PubMed / Full text
- [Frequency of some diseases and conditions in geriatric patients with coronary heart disease and various genotypes of transcription factor 7-like 2 protein]. / 2014 / PubMed
- Aging and cardiovascular diseases: the role of gene-diet interactions. / 11.2014 / PubMed / Full text
TET1[править]
- DNA methylation instability by BRAF-mediated TET silencing and lifestyle-exposure divides colon cancer pathways. / 16.12.2019 / PubMed / Full text
- Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords. / 02.2019 / PubMed / Full text
- Epigenetic Co-Deregulation of EZH2/TET1 is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer. / 2019 / PubMed / Full text
- DNA Hydroxymethylation Levels Are Altered in Blood Cells From Down Syndrome Persons Enrolled in the MARK-AGE Project. / 09.05.2018 / PubMed / Full text
- Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts. / 07.2014 / PubMed / Full text
- On your (methyl) mark, get TET1, go! / 01.08.2013 / PubMed / Full text
TLR3[править]
- Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. / 01.12.2020 / PubMed / Full text
- The Upregulation of Toll-Like Receptor 3 via Autocrine IFN-β Signaling Drives the Senescence of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Through JAK1. / 2019 / PubMed / Full text
- Repetitive TLR3 activation in the lung induces skeletal muscle adaptations and cachexia. / 06.2018 / PubMed / Full text
- Age-related changes and distribution of T cell markers (CD3 and CD4) and toll-like receptors(TLR2, TLR3,TLR4 and TLR7) in the duck lymphoid organs. / 07.2017 / PubMed / Full text
- Effect of age on the pathogenesis of DHV-1 in Pekin ducks and on the innate immune responses of ducks to infection. / 05.2014 / PubMed / Full text
- [What's new in dermatological research?]. / 12.2012 / PubMed / Full text
TPO[править]
- Megakaryocytes promote osteoclastogenesis in aging. / 07.07.2020 / PubMed / Full text
- To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex-independent) NOD.H2 mice. / 04.2019 / PubMed / Full text
- Kras is Required for Adult Hematopoiesis. / 07.2016 / PubMed / Full text
- Signal for Thrombosis with Eltrombopag and Romiplostim: A Disproportionality Analysis of Spontaneous Reports Within VigiBase®. / 12.2015 / PubMed / Full text
- Effect of different photoinitiators and reducing agents on cure efficiency and color stability of resin-based composites using different LED wavelengths. / 12.2015 / PubMed / Full text
- Complex reference value distributions and partitioned reference intervals across the pediatric age range for 14 specialized biochemical markers in the CALIPER cohort of healthy community children and adolescents. / 23.10.2015 / PubMed / Full text
TRPA1[править]
- Important regulatory function of transient receptor potential ankyrin 1 receptors in age-related learning and memory alterations of mice. / 10.2019 / PubMed / Full text
- Aging of mouse intervertebral disc and association with back pain. / 06.2019 / PubMed / Full text
- Congeneric variability in lifespan extension and onset of senescence suggest active regulation of aging in response to low temperature. / 12.2018 / PubMed / Full text
- A comparative study on the therapeutic effect of TRPV1, TRPA1, and TRPM8 agonists on swallowing dysfunction associated with aging and neurological diseases. / 02.2018 / PubMed / Full text
- A Caenorhabditis elegans Model Elucidates a Conserved Role for TRPA1-Nrf Signaling in Reactive α-Dicarbonyl Detoxification. / 21.11.2016 / PubMed / Full text
- A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel. / 14.02.2013 / PubMed / Full text
VIM[править]
- Establishment and characterization of a fibroblast cell line from postmortem skin of an adult Chinese muntjac (Muntiacus reevesi). / 02.2020 / PubMed / Full text
- The effect of test modality on dynamic exercise biomarkers in children, adolescents, and young adults. / 07.2019 / PubMed / Full text
- Centenarians Overexpress Pluripotency-Related Genes. / 16.08.2019 / PubMed / Full text
- Bioinformatics analysis of proteomics profiles in senescent human primary proximal tubule epithelial cells. / 01.04.2016 / PubMed / Full text
- Assessment of Age-Related Differences in Functional Capacity Using the Virtual Reality Functional Capacity Assessment Tool (VRFCAT). / 06.2015 / PubMed / Full text
- Reactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences. / 10.2015 / PubMed / Full text
ABCG2[править]
- Contribution of senescence in human endometrial stromal cells during proliferative phase to embryo receptivity†. / 23.06.2020 / PubMed / Full text
- ABCG2 rs2231142 variant in hyperuricemia is modified by SLC2A9 and SLC22A12 polymorphisms and cardiovascular risk factors in an elderly community-dwelling population. / 17.03.2020 / PubMed / Full text
- Morphological and immunohistochemical characteristics of the equine corneal epithelium. / 11.2019 / PubMed / Full text
- Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life. / 07.2016 / PubMed / Full text
- Gene specific epigenetic regulation of hepatic folate transport system is responsible for perturbed cellular folate status during aging and exogenous modulation. / 06.2016 / PubMed / Full text
ACOX1[править]
- Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes. / 04.2019 / PubMed / Full text
- Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging. / 2018 / PubMed / Full text
- Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. / 11.07.2017 / PubMed / Full text
- Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text
- Decreased liver peroxisomal β-oxidation accompanied by changes in brain fatty acid composition in aged rats. / 02.2014 / PubMed / Full text
AGTR1[править]
- Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study. / 2016 / PubMed / Full text
- Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age. / 01.11.2014 / PubMed / Full text
- Impact of the AGTR1 A1166C polymorphism on subcortical hyperintensities and cognition in healthy older adults. / 2014 / PubMed / Full text
- Influence of the AGTR1 A1166C genotype on the progression of arterial stiffness: A 16-year longitudinal study. / 12.2013 / PubMed / Full text
- Identification of RAS genotypes that modulate blood pressure change by outdoor temperature. / 06.2013 / PubMed / Full text
AIM2[править]
- Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of Apc mice. / 11.04.2017 / PubMed / Full text
- Reduced levels of cytosolic DNA sensor AIM2 are associated with impaired cytokine responses in healthy elderly. / 06.2016 / PubMed / Full text
- Gene expression of inflammasome components in peripheral blood mononuclear cells (PBMC) of vascular patients increases with age. / 2015 / PubMed / Full text
- Effects of aging in the expression of NOD-like receptors and inflammasome-related genes in oral mucosa. / 02.2016 / PubMed / Full text
- DAMPs, ageing, and cancer: The 'DAMP Hypothesis'. / 11.2015 / PubMed / Full text
ARMS2[править]
- Benefits, Potential Harms, and Optimal Use of Nutritional Supplementation for Preventing Progression of Age-Related Macular Degeneration. / 03.2017 / PubMed / Full text
- A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging. / 14.07.2016 / PubMed / Full text
- Mesopic Pelli-Robson contrast sensitivity and MP-1 microperimetry in healthy ageing and age-related macular degeneration. / 12.2016 / PubMed / Full text
- [Age-related Macular Degeneration in the Japanese]. / 03.2016 / PubMed
- Prevalence and Genetic Characteristics of Geographic Atrophy among Elderly Japanese with Age-Related Macular Degeneration. / 2016 / PubMed / Full text
BAD[править]
- I imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway. / 31.10.2020 / PubMed / Full text
- Xanthohumol exerts protective effects in liver alterations associated with aging. / 03.2019 / PubMed / Full text
- Protective effect of xanthohumol against age-related brain damage. / 11.2017 / PubMed / Full text
- Melatonin decreases the expression of inflammation and apoptosis markers in the lung of a senescence-accelerated mice model. / 03.2016 / PubMed / Full text
- Melatonin Counteracts at a Transcriptional Level the Inflammatory and Apoptotic Response Secondary to Ischemic Brain Injury Induced by Middle Cerebral Artery Blockade in Aging Rats. / 2015 / PubMed / Full text
BMPR2[править]
- Human placenta-derived mesenchymal stem cells stimulate ovarian function via miR-145 and bone morphogenetic protein signaling in aged rats. / 05.11.2020 / PubMed / Full text
- Centenarians Overexpress Pluripotency-Related Genes. / 16.08.2019 / PubMed / Full text
- Age-related expression of TGF beta family receptors in human cumulus oophorus cells. / 09.2017 / PubMed / Full text
- Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension. / 07.2015 / PubMed / Full text
- Update on pediatric pulmonary arterial hypertension. Differences and similarities to adult disease. / 2013 / PubMed / Full text
BPI[править]
- High TARC plasma levels confer protection to long living individuals by inducing M2 profile. / 01.2021 / PubMed / Full text
- Circulating BPIFB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals. / 2020 / PubMed / Full text
- The effect of postural deformities on back function and pain in patients with Parkinson's disease. / 2019 / PubMed / Full text
- The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy. / 22.01.2017 / PubMed / Full text
- Age-dependent expression of the BPI gene in Sutai piglets. / 28.06.2013 / PubMed / Full text
CCL3[править]
- Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: Sex differences and role of purinergic receptors. / 07.11.2020 / PubMed / Full text
- Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau. / 03.09.2018 / PubMed / Full text
- Time-Dependent Changes in Local and Serum Levels of Inflammatory Cytokines as Markers for Incised Wound Aging of Skeletal Muscles. / 05.2018 / PubMed / Full text
- Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor. / 2018 / PubMed / Full text
- Changes in the expression of the Toll-like receptor system in the aging rat kidneys. / 2014 / PubMed / Full text
CCNB1[править]
- The antioxidant icariin protects porcine oocytes from age-related damage in vitro. / 12.05.2020 / PubMed / Full text
- Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. / 01.2019 / PubMed / Full text
- Effect of CCNB1 silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer. / 01.2018 / PubMed / Full text
- Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan. / 31.03.2018 / PubMed / Full text
- Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. / 2013 / PubMed / Full text
CCND1[править]
- Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells. / 09.2020 / PubMed / Full text
- Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. / 03.2020 / PubMed / Full text
- Expansion of adipose tissue-derived stromal cells at "physiologic" hypoxia attenuates replicative senescence. / 06.2017 / PubMed / Full text
- Sporadic colorectal cancer development shows rejuvenescence regarding epithelial proliferation and apoptosis. / 2013 / PubMed / Full text
- Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes. / 15.08.2013 / PubMed / Full text
CD22[править]
- Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration. / 2020 / PubMed / Full text
- CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. / 04.2019 / PubMed / Full text
- Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves. / 03.2018 / PubMed / Full text
- Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice. / 01.07.2015 / PubMed / Full text
- Double negative (CD19 IgG IgD-CD27-) B lymphocytes: a new insight from telomerase in healthy elderly, in centenarian offspring and in Alzheimer's disease patients. / 11.2014 / PubMed / Full text
CD2AP[править]
- Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text
- Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population. / 11.04.2017 / PubMed / Full text
- Gene-based aggregate SNP associations between candidate AD genes and cognitive decline. / 04.2016 / PubMed / Full text
- HYDRA: Revealing heterogeneity of imaging and genetic patterns through a multiple max-margin discriminative analysis framework. / 15.01.2017 / PubMed / Full text
- Dendrin ablation prolongs life span by delaying kidney failure. / 08.2015 / PubMed / Full text
CD81[править]
- Ovarian aging increases small extracellular vesicle CD81 release in human follicular fluid and influences miRNA profiles. / 17.06.2020 / PubMed / Full text
- Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature. / 15.04.2020 / PubMed / Full text
- Increased production of functional small extracellular vesicles in senescent endothelial cells. / 04.2020 / PubMed / Full text
- Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. / 12.02.2020 / PubMed / Full text
- Extracellular Vesicles Derived from Senescent Fibroblasts Attenuate the Dermal Effect on Keratinocyte Differentiation. / 04.02.2020 / PubMed / Full text
CES1[править]
- [Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog]. / 2019 / PubMed / Full text
- Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants. / 02.2017 / PubMed / Full text
- Identifying clinically relevant sources of variability: The clopidogrel challenge. / 02.2017 / PubMed / Full text
- Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny. / 07.2016 / PubMed / Full text
- Distinct patterns of aging effects on the expression and activity of carboxylesterases in rat liver and intestine. / 02.2014 / PubMed / Full text
CFB[править]
- Effect of Age on the Efficacy and Safety of Once-Daily Single-Inhaler Triple Therapy Fluticasone Furoate/Umeclidinium/Vilanterol in Patients With Chronic Obstructive Pulmonary Disease: A Post Hoc Analysis of the IMPACT Trial. / 05.10.2020 / PubMed / Full text
- The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. / 13.06.2018 / PubMed / Full text
- Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue. / 05.2017 / PubMed / Full text
- Genetic factors associated with the development of age-related macular degeneration. / 2016 / PubMed / Full text
- Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation. / 10.2013 / PubMed / Full text
CLN3[править]
- SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text
- Age-dependent alterations in neuronal activity in the hippocampus and visual cortex in a mouse model of Juvenile Neuronal Ceroid Lipofuscinosis (CLN3). / 04.2017 / PubMed / Full text
- Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease). / 15.12.2015 / PubMed / Full text
- Finding the most appropriate mouse model of juvenile CLN3 (Batten) disease for therapeutic studies: the importance of genetic background and gender. / 04.2015 / PubMed / Full text
- Xbp1 directs global repression of budding yeast transcription during the transition to quiescence and is important for the longevity and reversibility of the quiescent state. / 10.2013 / PubMed / Full text
CXCR1[править]
- Harmful neutrophil subsets in patients with ischemic stroke: Association with disease severity. / 07.2019 / PubMed / Full text
- Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells. / 15.06.2017 / PubMed / Full text
- The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via CXCR1-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs. / 01.2017 / PubMed / Full text
- Habitual physical activity is associated with the maintenance of neutrophil migratory dynamics in healthy older adults. / 08.2016 / PubMed / Full text
- Activation profile of CXCL8-stimulated neutrophils and aging. / 03.2013 / PubMed / Full text
DKC1[править]
- CD8 T-cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with PARN and DKC1 mutations. / 09.2020 / PubMed / Full text
- Successful liver transplantation in short telomere syndromes without bone marrow failure due to DKC1 mutation. / 05.2020 / PubMed / Full text
- Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. / 04.2018 / PubMed / Full text
- Cinnamaldehyde and eugenol change the expression folds of AKT1 and DKC1 genes and decrease the telomere length of human adipose-derived stem cells (hASCs): An experimental and in silico study. / 03.2017 / PubMed / Full text
- Molecular adaptation of telomere associated genes in mammals. / 15.11.2013 / PubMed / Full text
DMP1[править]
- GREM1 inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. / 09.03.2020 / PubMed / Full text
- Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice. / 07.2018 / PubMed / Full text
- [i]Dmp1[/i] Null Mice Develop a Unique Osteoarthritis-like Phenotype. / 2016 / PubMed / Full text
- Decline in calcitonin receptor expression in osteocytes with age. / 05.2014 / PubMed / Full text
- Novel sandwich ELISAs for rat DMP1: age-related decrease of circulatory DMP1 levels in male rats. / 12.2013 / PubMed / Full text
DRD4[править]
- ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children. / 04.2019 / PubMed / Full text
- Age-dependent role of pre- and perinatal factors in interaction with genes on ADHD symptoms across adolescence. / 07.2017 / PubMed / Full text
- Association between dopamine D4 receptor polymorphism and age related changes in brain glucose metabolism. / 2013 / PubMed / Full text
- Polymorphic variants of neurotransmitter receptor genes may affect sexual function in aging males: data from the HALS study. / 2013 / PubMed / Full text
- DRD4 genotype predicts longevity in mouse and human. / 02.01.2013 / PubMed / Full text
DST[править]
- Ancestral germen/soma distinction in microbes: Expanding the disposable soma theory of aging to all unicellular lineages. / 07.2020 / PubMed / Full text
- Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study. / 10.2019 / PubMed / Full text
- The associations between diet quality, Body Mass Index (BMI) and Health and Activity Limitation Index (HALex) in the Geisinger Rural Aging Study (GRAS). / 2014 / PubMed / Full text
- Depression-like behavior is dependent on age in male SAMP8 mice. / 04.2013 / PubMed / Full text
- Swallowing disorders in nursing home residents: how can the problem be explained? / 2013 / PubMed / Full text
E2F3[править]
- Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution. / 07.2018 / PubMed / Full text
- miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions. / 01.03.2017 / PubMed / Full text
- Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution. / 09.10.2014 / PubMed / Full text
- Tumor-suppressive microRNA-449a induces growth arrest and senescence by targeting E2F3 in human lung cancer cells. / 28.03.2014 / PubMed / Full text
- Elevated miR-34c-5p mediates dermal fibroblast senescence by ultraviolet irradiation. / 2013 / PubMed / Full text
ERAS[править]
- Enhanced Recovery After Surgery: Are the Principles Applicable to Adult and Geriatric Acute Care and Trauma Surgery? / 03.2019 / PubMed / Full text
- Prospective application of an implementation framework to improve postoperative nutrition care processes: Evaluation of a mixed methods implementation study. / 09.2018 / PubMed / Full text
- Enhanced Recovery After Surgery (ERAS) - The Evidence in Geriatric Emergency Surgery: A Systematic Review. / Sept-10.2017 / PubMed / Full text
- Multimodal Rehabilitation in Geriatric Emergency Surgery. / Sept-10.2017 / PubMed / Full text
- Surgical Stress Reduction in Elderly Patients Undergoing Elective Colorectal Laparoscopic Surgery within an ERAS Protocol. / 11-12.2016 / PubMed / Full text
FBL[править]
- APPLICATION OF A NOVEL QUANTITATIVE TRACTOGRAPHY-BASED ANALYSIS OF DIFFUSION TENSOR IMAGING TO EXAMINE FIBER BUNDLE LENGTH IN HUMAN CEREBRAL WHITE MATTER. / 04.2016 / PubMed / Full text
- Cognitive reserve moderates the relationship between neuropsychological performance and white matter fiber bundle length in healthy older adults. / 06.2017 / PubMed / Full text
- Fiber bundle length and cognition: a length-based tractography MRI study. / 12.2015 / PubMed / Full text
- White matter changes with age utilizing quantitative diffusion MRI. / 15.07.2014 / PubMed / Full text
- Impact of body mass index on neuronal fiber bundle lengths among healthy older adults. / 09.2013 / PubMed / Full text
FGA[править]
- Goal Pursuit, Goal Adjustment, and Pain in Middle-Aged Adults Aging With Physical Disability. / 12.2019 / PubMed / Full text
- Tenacious Goal Pursuit, Flexible Goal Adjustment, and Life Satisfaction Among Chinese Older Adult Couples. / 01.2020 / PubMed / Full text
- Association of tenacious goal pursuit and flexible goal adjustment with out-of-home mobility among community-dwelling older people. / 09.2019 / PubMed / Full text
- Assimilative and accommodative coping in older adults with and without sensory impairment: four-year change and prospective relations with affective well-being. / 09.2019 / PubMed / Full text
- Age stereotypes, flexible goal adjustment, and well-being among Chinese older adults. / 02.2018 / PubMed / Full text
FOXA1[править]
- Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer. / 28.09.2019 / PubMed / Full text
- The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. / 05.06.2018 / PubMed / Full text
- FOXA1 and SOX9 Expression in the Developing Urogenital Sinus of the Tammar Wallaby (Macropus eugenii). / 2015 / PubMed / Full text
- Epigenetic mechanisms of peptidergic regulation of gene expression during aging of human cells. / 03.2015 / PubMed / Full text
- Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. / 06.2014 / PubMed / Full text
FOXN1[править]
- Thymic rejuvenation via FOXN1-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation. / 17.09.2020 / PubMed / Full text
- Role of Bone Marrow Maturity, Insulin-Like Growth Factor 1 Receptor, and Forkhead Box Protein N1 in Thymic Involution and Rejuvenation. / 10.2016 / PubMed / Full text
- Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution. / 2016 / PubMed / Full text
- A deletion in FOXN1 is associated with a syndrome characterized by congenital hypotrichosis and short life expectancy in Birman cats. / 2015 / PubMed / Full text
- Regeneration of the aged thymus by a single transcription factor. / 04.2014 / PubMed / Full text
FOXO6[править]
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
- Introduction to FOXO Biology. / 2019 / PubMed / Full text
- FOXO in Neural Cells and Diseases of the Nervous System. / 2018 / PubMed / Full text
- FOXO Transcriptional Factors and Long-Term Living. / 2017 / PubMed / Full text
- Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. / 04.2016 / PubMed / Full text
GDF9[править]
- Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-KIT. / 04.2020 / PubMed / Full text
- Single xenotransplant of rat brown adipose tissue prolonged the ovarian lifespan of aging mice by improving follicle survival. / 12.2019 / PubMed / Full text
- Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. / 18.10.2017 / PubMed / Full text
- Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. / 07.2015 / PubMed / Full text
- Identification of a mutation in GDF9 as a novel cause of diminished ovarian reserve in young women. / 09.2013 / PubMed / Full text
GGCT[править]
- Blockade of γ-Glutamylcyclotransferase Enhances Docetaxel Growth Inhibition of Prostate Cancer Cells. / 09.2019 / PubMed / Full text
- Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase (GGCT): A Novel Molecular Target for Anticancer Therapy. / 14.07.2018 / PubMed / Full text
- Depletion of gamma-glutamylcyclotransferase in cancer cells induces autophagy followed by cellular senescence. / 2018 / PubMed / Full text
- Prohibitin-2 is a novel regulator of p21 induced by depletion of γ-glutamylcyclotransferase. / 29.01.2018 / PubMed / Full text
- Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation. / 22.09.2016 / PubMed / Full text
GIT2[править]
- The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage. / 03.12.2019 / PubMed / Full text
- Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories. / 12.2019 / PubMed / Full text
- GIT2-A keystone in ageing and age-related disease. / 05.2018 / PubMed / Full text
- Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption. / 04.03.2017 / PubMed / Full text
- GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging. / 2015 / PubMed / Full text
GPX4[править]
- l-carnitine supplementation during in vitro culture regulates oxidative stress in embryos from bovine aged oocytes. / 02.2020 / PubMed / Full text
- Dietary Selenium Supplementation Ameliorates Female Reproductive Efficiency in Aging Mice. / 11.12.2019 / PubMed / Full text
- Resveratrol improves in vitro maturation of oocytes in aged mice and humans. / 05.2018 / PubMed / Full text
- Differential menopause- versus aging-induced changes in oxidative stress and circadian rhythm gene markers. / 06.2017 / PubMed / Full text
- Maternal obesity in the rat impairs male offspring aging of the testicular antioxidant defence system. / 09.2017 / PubMed / Full text
GRK2[править]
- G protein-coupled receptor kinase 2 modifies the ability of Caenorhabditis elegans to survive oxidative stress. / 16.10.2020 / PubMed / Full text
- G protein coupled receptor kinases modulate Caenorhabditis elegans reactions to heat stresses. / 01.10.2020 / PubMed / Full text
- Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging. / 01.05.2020 / PubMed / Full text
- Senescent Cells Differentially Translate Senescence-Related mRNAs Via Ribosome Heterogeneity. / 18.06.2019 / PubMed / Full text
- Effects of exercise training on cardiovascular adrenergic system. / 28.11.2013 / PubMed / Full text
HAS2[править]
- Sodium tanshinone IIA sulfonate restrains fibrogenesis through induction of senescence in mice with induced deep endometriosis. / 09.2020 / PubMed / Full text
- Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. / 01.2018 / PubMed / Full text
- Microvasculature of the Mouse Cerebral Cortex Exhibits Increased Accumulation and Synthesis of Hyaluronan With Aging. / 01.06.2017 / PubMed / Full text
- Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. / 09.2016 / PubMed / Full text
- Age-associated changes in gene expression of goat oocytes. / 01.09.2013 / PubMed / Full text
HCN2[править]
- Protein expression changes of HCN1 and HCN2 in hippocampal subregions of gerbils during the normal aging process. / 11.2019 / PubMed / Full text
- Characteristics of hyperpolarization-activated cyclic nucleotide-gated channels in dorsal root ganglion neurons at different ages and sizes. / 11.11.2015 / PubMed / Full text
- Age-associated expression of HCN channel isoforms in rat sinoatrial node. / 02.2016 / PubMed / Full text
- Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation. / 09.2015 / PubMed / Full text
- Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse. / 27.02.2015 / PubMed / Full text
HSPA8[править]
- Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text
- Influence of Normal Aging on Brain Autophagy: A Complex Scenario. / 2019 / PubMed / Full text
- Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone HSPA8 and the ubiquitin ligase UBE2D. / 01.2019 / PubMed / Full text
- Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging. / 2018 / PubMed / Full text
- Age-Related Decrease in Heat Shock 70-kDa Protein 8 in Cerebrospinal Fluid Is Associated with Increased Oxidative Stress. / 2016 / PubMed / Full text
IDH1[править]
- Oxidative Damage to the TCA Cycle Enzyme MDH1 Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. / 03.04.2020 / PubMed / Full text
- An integrated metabolomic and gene expression analysis identifies heat and calcium metabolic networks underlying postharvest sweet cherry fruit senescence. / 12.2019 / PubMed / Full text
- GBM-associated mutations and altered protein expression are more common in young patients. / 25.10.2016 / PubMed / Full text
- IDH1 Associated with Neuronal Apoptosis in Adult Rats Brain Following Intracerebral Hemorrhage. / 07.2017 / PubMed / Full text
- 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. / 01.09.2015 / PubMed / Full text
IRS2[править]
- Effects of Heshouwuyin on gene expression of the insulin/IGF signalling pathway in rat testis and spermatogenic cells. / 12.2020 / PubMed / Full text
- Involvement of insulin receptor substrates in cognitive impairment and Alzheimer's disease. / 08.2019 / PubMed / Full text
- The senescent status of endothelial cells affects proliferation, inflammatory profile and SOX2 expression in bone marrow-derived mesenchymal stem cells. / 06.2019 / PubMed / Full text
- Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text
- Analysis of MTNR1B gene polymorphisms in relationship with IRS2 gene variants, epicardial fat thickness, glucose homeostasis and cognitive performance in the elderly. / 2017 / PubMed / Full text
KCNB1[править]
- Oxidation of KCNB1 potassium channels in the murine brain during aging is associated with cognitive impairment. / 14.05.2019 / PubMed / Full text
- Oxidation of KCNB1 Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury. / 26.10.2016 / PubMed / Full text
- Oxidation of K( ) Channels in Aging and Neurodegeneration. / 03.2016 / PubMed / Full text
- Oxidation of KCNB1 K( ) channels in central nervous system and beyond. / 26.05.2014 / PubMed / Full text
- Molecular mechanisms underlying the apoptotic effect of KCNB1 K channel oxidation. / 08.02.2013 / PubMed / Full text
KISS1[править]
- In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text
- Kisspeptin level in the aging ovary is regulated by the sympathetic nervous system. / 01.2017 / PubMed / Full text
- Kisspeptin across the human lifespan:evidence from animal studies and beyond. / 06.2016 / PubMed / Full text
- Effects of Age and Estradiol on Gene Expression in the Rhesus Macaque Hypothalamus. / 2015 / PubMed / Full text
- [Profiles of reproduction-related mRNA expressions in hypothalamus of female mice with advancing age]. / 17.12.2013 / PubMed
LIF[править]
- Use of the Reversible Myogenic to Lipogenic Transdifferentiation Switch for the Design of Pre-clinical Drug Screening in Idiopathic Pulmonary Fibrosis. / 2020 / PubMed / Full text
- Aminopeptidase N expression in the endometrium could affect endometrial receptivity. / 25.06.2019 / PubMed / Full text
- Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. / 15.03.2019 / PubMed / Full text
- Assaying human neutrophil elastase activity by capillary zone electrophoresis combined with laser-induced fluorescence. / 06.11.2015 / PubMed / Full text
- iPSCs, aging and age-related diseases. / 25.09.2014 / PubMed / Full text
LONP1[править]
- Improved mitochondrial stress response in long-lived Snell dwarf mice. / 12.2019 / PubMed / Full text
- Mitochondria organize the cellular proteostatic response and promote cellular senescence. / 15.03.2019 / PubMed / Full text
- A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. / 01.02.2019 / PubMed / Full text
- Mitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disorders. / 11.2016 / PubMed / Full text
- Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer. / 10-12.2014 / PubMed / Full text
MAPK14[править]
- Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. / 03.2020 / PubMed / Full text
- Chlorella vulgaris modulates the expression of senescence-associated genes in replicative senescence of human diploid fibroblasts. / 01.2020 / PubMed / Full text
- Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. / 10.2018 / PubMed / Full text
- G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
- Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts. / 11-12.2015 / PubMed / Full text
MARCKS[править]
- Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. / 07-08.2018 / PubMed / Full text
- MARCKS contributes to stromal cancer-associated fibroblast activation and facilitates ovarian cancer metastasis. / 21.06.2016 / PubMed / Full text
- MARCKS-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging. / 10.2015 / PubMed / Full text
- The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release. / 10.02.2015 / PubMed / Full text
- Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of MARCKS. / 04.2013 / PubMed / Full text
MGP[править]
- Circulating Vitamin K Is Inversely Associated with Incident Cardiovascular Disease Risk among Those Treated for Hypertension in the Health, Aging, and Body Composition Study (Health ABC). / 05.2017 / PubMed / Full text
- Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma. / 21.12.2016 / PubMed / Full text
- [Bone metabolism and cardiovascular function update. Cross link of hypertension, bone loss and vascular calcification - common back grounds in renin angiotensin system with anti-aging aspect -]. / 07.2014 / PubMed / Full text
- Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease. / 02.2014 / PubMed / Full text
- Elastin haploinsufficiency impedes the progression of arterial calcification in MGP-deficient mice. / 02.2014 / PubMed / Full text
MLKL[править]
- Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3. / 18.11.2020 / PubMed / Full text
- Remifentanil preconditioning protects against hypoxia-induced senescence and necroptosis in human cardiac myocytes [i]in vitro[/i]. / 25.06.2020 / PubMed / Full text
- Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma. / 05.2020 / PubMed / Full text
- Necroptosis increases with age and is reduced by dietary restriction. / 08.2018 / PubMed / Full text
- RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system. / 15.08.2017 / PubMed / Full text
MLN[править]
- Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells. / 2020 / PubMed / Full text
- Variability of Spleen and Mesenteric Lymph Node in Control Cynomolgus Monkeys ( Macaca fascicularis) from Nonclinical Safety Studies: A Retrospective Assessment. / 01.2019 / PubMed / Full text
- Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life. / 03.2019 / PubMed / Full text
- Immunological Basis for Rapid Progression of Diabetes in Older NOD Mouse Recipients Post BM-HSC Transplantation. / 2015 / PubMed / Full text
- Association between Mycobacterium avium subspecies paratuberculosis and lymph node size in New Zealand farmed deer (Cervus elaphus). / 05.2013 / PubMed / Full text
NBR1[править]
- Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3. / 04.11.2020 / PubMed / Full text
- New insights into AtNBR1 as a selective autophagy cargo receptor in Arabidopsis. / 30.10.2020 / PubMed / Full text
- SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence. / 06.2020 / PubMed / Full text
- Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner. / 03.2018 / PubMed / Full text
- Overweight in elderly people induces impaired autophagy in skeletal muscle. / 09.2017 / PubMed / Full text
NEDD8[править]
- Targeting Protein Neddylation for Cancer Therapy. / 2020 / PubMed / Full text
- Effective targeting of the ubiquitin-like modifier NEDD8 for lung adenocarcinoma treatment. / 08.2020 / PubMed / Full text
- Pevonedistat targeted therapy inhibits canine melanoma cell growth through induction of DNA re-replication and senescence. / 09.2020 / PubMed / Full text
- Protein neddylation and its alterations in human cancers for targeted therapy. / 04.2018 / PubMed / Full text
- Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells. / 2015 / PubMed / Full text
NFE2L2[править]
- The double-edged sword of MTOR in autophagy deficiency induced-liver injury and tumorigenesis. / 09.2019 / PubMed / Full text
- The Association of a Single-Nucleotide Polymorphism in the Nuclear Factor (Erythroid-Derived 2)-Like 2 Gene With Adverse Drug Reactions, Multimorbidity, and Frailty in Older People. / 22.05.2020 / PubMed / Full text
- Immunohistochemical localization of Nrf2 in the human cochlea. / 01.12.2018 / PubMed / Full text
- Lifespan extension by peroxidase and dual oxidase-mediated ROS signaling through pyrroloquinoline quinone in [i]C. elegans[/i]. / 01.08.2017 / PubMed / Full text
- Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. / 02.11.2015 / PubMed / Full text
NPC2[править]
- Attenuation of the Niemann-Pick type C2 disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2. / 08.2018 / PubMed / Full text
- Quantification of age-related changes of α-tocopherol in lysosomal membranes in murine tissues and human fibroblasts. / 05.2016 / PubMed / Full text
- Systemic administration of 2-hydroxypropyl-β-cyclodextrin to symptomatic Npc1-deficient mice slows cholesterol sequestration in the major organs and improves liver function. / 10.2014 / PubMed / Full text
- Niemann-Pick C disease gene mutations and age-related neurodegenerative disorders. / 2013 / PubMed / Full text
- Ontogenic changes in lung cholesterol metabolism, lipid content, and histology in mice with Niemann-Pick type C disease. / 01.2014 / PubMed / Full text
NRG1[править]
- Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis. / 29.07.2016 / PubMed / Full text
- Neuregulin-1 Administration Protocols Sufficient for Stimulating Cardiac Regeneration in Young Mice Do Not Induce Somatic, Organ, or Neoplastic Growth. / 2016 / PubMed / Full text
- Neuregulin 1 improves glucose tolerance in adult and old rats. / 04.2016 / PubMed / Full text
- Disruption of hippocampal neuregulin 1-ErbB4 signaling contributes to the hippocampus-dependent cognitive impairment induced by isoflurane in aged mice. / 07.2014 / PubMed / Full text
- ErbB2 receptor over-expression improves post-traumatic peripheral nerve regeneration in adult mice. / 2013 / PubMed / Full text
PDE4D[править]
- Phosphodiesterase PDE4D Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau. / 2020 / PubMed / Full text
- Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function. / 02.12.2018 / PubMed / Full text
- The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation. / 08.2017 / PubMed / Full text
- Effects of aging on gene expression and mitochondrial DNA in the equine oocyte and follicle cells. / 07.2015 / PubMed / Full text
- Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain. / 02.2014 / PubMed / Full text
PDF[править]
- Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models. / 28.05.2019 / PubMed / Full text
- Drosophila Clock Is Required in Brain Pacemaker Neurons to Prevent Premature Locomotor Aging Independently of Its Circadian Function. / 01.2017 / PubMed / Full text
- SnapShot: Neuronal Regulation of Aging. / 28.07.2016 / PubMed / Full text
- Recent data on Mediterranean diet, cardiovascular disease, cancer, diabetes and life expectancy. / 2015 / PubMed / Full text
- Pigment-dispersing factor is involved in age-dependent rhythm changes in Drosophila melanogaster. / 12.2012 / PubMed / Full text
PIN1[править]
- Brain somatic mutations observed in Alzheimer's disease associated with aging and dysregulation of tau phosphorylation. / 12.07.2019 / PubMed / Full text
- Class XI Myosins Contribute to Auxin Response and Senescence-Induced Cell Death in [i]Arabidopsis[/i]. / 2018 / PubMed / Full text
- Effects of Melatonin and Its Underlying Mechanism on Ethanol-Stimulated Senescence and Osteoclastic Differentiation in Human Periodontal Ligament Cells and Cementoblasts. / 12.06.2018 / PubMed / Full text
- Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text
- Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy. / 03.2017 / PubMed / Full text
PLAU[править]
- Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging. / 11.2020 / PubMed / Full text
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
- Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text
- G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text
- Functional networks of aging markers in the glomeruli of IgA nephropathy: a new therapeutic opportunity. / 07.06.2016 / PubMed / Full text
POLD1[править]
- Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes. / 10.2019 / PubMed / Full text
- POLD1 deficiency is involved in cognitive function impairment in AD patients and SAMP8 mice. / 06.2019 / PubMed / Full text
- E2F1 mediates the downregulation of POLD1 in replicative senescence. / 07.2019 / PubMed / Full text
- Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing. / 03.2018 / PubMed / Full text
- POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies. / 15.09.2016 / PubMed / Full text
POU5F1[править]
- Cell quality evaluation with gene expression analysis of spheroids (3D) and adherent (2D) adipose stem cells. / 24.10.2020 / PubMed / Full text
- Enhanced proliferative capacity of human preadipocytes achieved by an optimized cultivating method that induces transient activity of hTERT. / 20.08.2020 / PubMed / Full text
- Autophagic homeostasis is required for the pluripotency of cancer stem cells. / 02.2017 / PubMed / Full text
- Characterization of the POU5F1 Homologue in Nile Tilapia: From Expression Pattern to Biological Activity. / 15.09.2016 / PubMed / Full text
- Determination phase at transition of gonocytes to spermatogonial stem cells improves establishment efficiency of spermatogonial stem cells in domestic cats. / 2015 / PubMed / Full text
PRMT1[править]
- Reactive oxygen species extend insect life span using components of the insulin-signaling pathway. / 12.09.2017 / PubMed / Full text
- Regenerating muscle with arginine methylation. / 27.05.2017 / PubMed / Full text
- Simultaneous ablation of prmt-1 and prmt-5 abolishes asymmetric and symmetric arginine dimethylations in Caenorhabditis elegans. / 01.06.2017 / PubMed / Full text
- Caveolin1/protein arginine methyltransferase1/sirtuin1 axis as a potential target against endothelial dysfunction. / 05.2017 / PubMed / Full text
- Epigallocatechin-3-gallate ameliorates erectile function in aged rats via regulation of PRMT1/DDAH/ADMA/NOS metabolism pathway. / 05-06.2017 / PubMed / Full text
RACK1[править]
- Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging. / 05.11.2019 / PubMed / Full text
- Role of Hormones in the Regulation of RACK1 Expression as a Signaling Checkpoint in Immunosenescence. / 06.07.2017 / PubMed / Full text
- Transcriptional regulation of RACK1 and modulation of its expression: Role of steroid hormones and significance in health and aging. / 07.2017 / PubMed / Full text
- Role of androgens in dhea-induced rack1 expression and cytokine modulation in monocytes. / 2016 / PubMed / Full text
- Immunostimulatory effects of RACK1 pseudosubstrate in human leukocytes obtained from young and old donors. / 30.03.2015 / PubMed / Full text
REN[править]
- In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text
- The Hispanic Paradox: Race/Ethnicity and Nativity, Immigrant Enclave Residence and Cognitive Impairment Among Older US Adults. / 05.2017 / PubMed / Full text
- Analysis of Clinical Features and Outcomes of Skull Base Chordoma in Different Age-Groups. / 08.2016 / PubMed / Full text
- Effects of advanced age and renal dysfunction on the single- and repeated-dose pharmacokinetics of modified-release flupirtine. / 03.2015 / PubMed / Full text
- Mapping nutrient resorption efficiencies of subarctic cryptogams and seed plants onto the Tree of Life. / 06.2014 / PubMed / Full text
RHO[править]
- Conditional reprogramming: next generation cell culture. / 08.2020 / PubMed / Full text
- SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells. / 18.05.2020 / PubMed / Full text
- Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity and Aging. / 28.09.2018 / PubMed / Full text
- NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through [i]memo-1[/i] in [i]C. elegans[/i]. / 13.01.2017 / PubMed / Full text
- Guanine nucleotide exchange factor OSG-1 confers functional aging via dysregulated Rho signaling in Caenorhabditis elegans neurons. / 02.2015 / PubMed / Full text
RICTOR[править]
- Proteomics of Long-Lived Mammals. / 03.2020 / PubMed / Full text
- Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. / 11.2019 / PubMed / Full text
- The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging. / 16.08.2016 / PubMed / Full text
- Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan. / 10.2014 / PubMed / Full text
- Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry. / 02.2015 / PubMed / Full text
RPE65[править]
- Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells. / 08.2018 / PubMed / Full text
- Age-related macular degeneration phenotypes are associated with increased tumor necrosis-alpha and subretinal immune cells in aged Cxcr5 knockout mice. / 2017 / PubMed / Full text
- The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling. / 04.2017 / PubMed / Full text
- Thinning of the RPE and choroid associated with T lymphocyte recruitment in aged and light-challenged mice. / 2015 / PubMed / Full text
- Update on current and future novel therapies for dry age-related macular degeneration. / 09.2013 / PubMed / Full text
SDHB[править]
- Older Adults with Physical Frailty and Sarcopenia Show Increased Levels of Circulating Small Extracellular Vesicles with a Specific Mitochondrial Signature. / 15.04.2020 / PubMed / Full text
- Oxidative Damage to the TCA Cycle Enzyme MDH1 Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. / 03.04.2020 / PubMed / Full text
- Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. / 12.02.2020 / PubMed / Full text
- Mitochondrial bioenergetics and disease in Caenorhabditis elegans. / 01.01.2015 / PubMed / Full text
- Long-term prognosis of patients with pediatric pheochromocytoma. / 02.2014 / PubMed / Full text
SFRP1[править]
- [Role and alterations of DNA methylation during the aging and cancer]. / 01.2018 / PubMed / Full text
- Age-related increase in Wnt inhibitor causes a senescence-like phenotype in human cardiac stem cells. / 03.06.2017 / PubMed / Full text
- Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma. / 21.12.2016 / PubMed / Full text
- The intrinsic stiffness of human trabecular meshwork cells increases with senescence. / 20.06.2015 / PubMed / Full text
- Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans. / 02.2014 / PubMed / Full text
SMAD4[править]
- A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient. / 09.2019 / PubMed / Full text
- E47 Governs the MYC-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type p53. / 2018 / PubMed / Full text
- iTRAQ-based proteomic profiling of granulosa cells from lamb and ewe after superstimulation. / 01.10.2017 / PubMed / Full text
- miR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4. / 01.08.2015 / PubMed / Full text
- Loss of smad4 in Sertoli and Leydig cells leads to testicular dysgenesis and hemorrhagic tumor formation in mice. / 03.2014 / PubMed / Full text
SMN2[править]
- Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. / 01.11.2019 / PubMed / Full text
- Type 0 Spinal Muscular Atrophy: Further Delineation of Prenatal and Postnatal Features in 16 Patients. / 29.11.2016 / PubMed / Full text
- Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy. / 27.09.2016 / PubMed / Full text
- Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy. / 08.08.2014 / PubMed / Full text
- Development and characterization of an SMN2-based intermediate mouse model of Spinal Muscular Atrophy. / 01.05.2013 / PubMed / Full text
SMS[править]
- Does a Live Performance Impact Synchronization to Musical Rhythm in Cognitively Impaired Elderly? / 2020 / PubMed / Full text
- Testing the effectiveness of physical activity advice delivered via text messaging vs. human phone advisors in a Latino population: The On The Move randomized controlled trial design and methods. / 08.2020 / PubMed / Full text
- Mobile Health Interventions for Physical Activity, Sedentary Behavior, and Sleep in Adults Aged 50 Years and Older: A Systematic Literature Review. / 01.08.2019 / PubMed / Full text
- Senescence-messaging secretome factors trigger premature senescence in human endometrium-derived stem cells. / 19.02.2018 / PubMed / Full text
- PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice. / 13.05.2014 / PubMed / Full text
SOCS1[править]
- Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. / 06.2019 / PubMed / Full text
- SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes. / 28.10.2017 / PubMed / Full text
- Daily Socs1 rhythms alter with aging differentially in peripheral clocks in male Wistar rats: therapeutic effects of melatonin. / 06.2017 / PubMed / Full text
- Differential response to intrahippocampal interleukin-4/interleukin-13 in aged and exercise mice. / 20.02.2017 / PubMed / Full text
- Aging diminishes the resistance of AO rats to EAE: putative role of enhanced generation of GM-CSF Expressing CD4 T cells in aged rats. / 2015 / PubMed / Full text
SP1[править]
- The effects and mechanism of collagen peptide and elastin peptide on skin aging induced by D-galactose combined with ultraviolet radiation. / 09.2020 / PubMed / Full text
- Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
- Downregulation of CITED2 contributes to TGFβ-mediated senescence of tendon-derived stem cells. / 04.2017 / PubMed / Full text
- Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase. / 01.2015 / PubMed / Full text
- A functional and genetic analysis of SOD2 promoter variants and their contribution to age-related hearing loss. / 07-08.2013 / PubMed / Full text
SSB[править]
- Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study. / 03.12.2019 / PubMed / Full text
- WHIRLY1 Occupancy Affects Histone Lysine Modification and [i]WRKY53[/i] Transcription in [i]Arabidopsis[/i] Developmental Manner. / 2018 / PubMed / Full text
- Modelled health benefits of a sugar-sweetened beverage tax across different socioeconomic groups in Australia: A cost-effectiveness and equity analysis. / 06.2017 / PubMed / Full text
- Reduction of Sugar-Sweetened Beverage Consumption in Elementary School Students Using an Educational Curriculum of Beverage Sugar Content. / 2017 / PubMed / Full text
- Interannual and Spatial Variability in Maturity of Walleye Pollock Gadus chalcogrammus and Implications for Spawning Stock Biomass Estimates in the Gulf of Alaska. / 2016 / PubMed / Full text
TBC1D1[править]
- Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text
- Calorie restriction leads to greater Akt2 activity and glucose uptake by insulin-stimulated skeletal muscle from old rats. / 01.03.2016 / PubMed / Full text
- Insulin Signaling and Glucose Uptake in the Soleus Muscle of 30-Month-Old Rats After Calorie Restriction With or Without Acute Exercise. / 03.2016 / PubMed / Full text
- Effects of sex and age on chicken TBC1D1 gene mRNA expression. / 13.07.2015 / PubMed / Full text
- AMPK and insulin action--responses to ageing and high fat diet. / 2013 / PubMed / Full text
TGFB1[править]
- Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. / 21.12.2019 / PubMed / Full text
- TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands. / 26.11.2019 / PubMed / Full text
- Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease. / 11.2017 / PubMed / Full text
- Seminal plasma transforming growth factor-β, activin A and follistatin fluctuate within men over time. / 10.2016 / PubMed / Full text
- No Association between Variation in Longevity Candidate Genes and Aging-related Phenotypes in Oldest-old Danes. / 06.2016 / PubMed / Full text
TLR1[править]
- Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. / 01.12.2020 / PubMed / Full text
- Association of TLR gene variants in a Czech Red Pied cattle population with reproductive traits. / 02.2020 / PubMed / Full text
- Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection. / 05.2018 / PubMed / Full text
- Changes in the expression of the Toll-like receptor system in the aging rat kidneys. / 2014 / PubMed / Full text
- Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging. / 02.2014 / PubMed / Full text
TLR8[править]
- Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle. / 01.12.2020 / PubMed / Full text
- TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy. / 08.01.2019 / PubMed / Full text
- Controlling T cell senescence in the tumor microenvironment for tumor immunotherapy. / 03.2015 / PubMed / Full text
- Cathelicidin related antimicrobial peptide, laminin, Toll-like receptors and chemokines levels in experimental hypersensitivity pneumonitis in mice. / 06.2015 / PubMed / Full text
- TLR8 signaling enhances tumor immunity by preventing tumor-induced T-cell senescence. / 10.2014 / PubMed / Full text
TMPRSS2[править]
- ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19. / 2020 / PubMed / Full text
- Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis. / 2020 / PubMed / Full text
- Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants. / 09.09.2020 / PubMed / Full text
- Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. / 03.06.2020 / PubMed / Full text
- SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells. / 18.05.2020 / PubMed / Full text
TRH[править]
- Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats. / 15.03.2018 / PubMed / Full text
- Effect of dietary carbohydrates and time of year on ACTH and cortisol concentrations in adult and aged horses. / 04.2018 / PubMed / Full text
- The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases. / 2013 / PubMed / Full text
- Aging-reversing properties of thyrotropin-releasing hormone. / 02.2013 / PubMed / Full text
- Cancer-related fatigue, inflammation and thyrotropin-releasing hormone. / 12.2012 / PubMed / Full text
TRPM8[править]
- Morphological and functional changes in TRPM8-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice. / 01.08.2018 / PubMed / Full text
- A comparative study on the therapeutic effect of TRPV1, TRPA1, and TRPM8 agonists on swallowing dysfunction associated with aging and neurological diseases. / 02.2018 / PubMed / Full text
- Roles of TRPM8 Ion Channels in Cancer: Proliferation, Survival, and Invasion. / 23.10.2015 / PubMed / Full text
- Function and postnatal changes of dural afferent fibers expressing TRPM8 channels. / 26.06.2015 / PubMed / Full text
- Induction of oxidative stress causes functional alterations in mouse urothelium via a TRPM8-mediated mechanism: implications for aging. / 06.2014 / PubMed / Full text
VCP[править]
- The role of air pollution and lung function in cognitive impairment. / 02.2018 / PubMed / Full text
- Better parameters of ventilation-CO₂output relationship predict death in CHF patients. / 11.2015 / PubMed
- Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal. / 22.03.2016 / PubMed / Full text
- Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis. / 24.02.2016 / PubMed / Full text
- Characterization of C-terminal adaptors, UFD-2 and UFD-3, of CDC-48 on the polyglutamine aggregation in C. elegans. / 27.03.2015 / PubMed / Full text
WAS[править]
- Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number. / 09.11.2017 / PubMed / Full text
- Measuring Work Ability with Its Antecedents: Evaluation of the Work Ability Survey. / 06.2018 / PubMed / Full text
- CONSTANCES: a general prospective population-based cohort for occupational and environmental epidemiology: cohort profile. / 01.2017 / PubMed / Full text
- Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice. / 2015 / PubMed / Full text
- Long-term anticoagulation in the extreme elderly with the newer antithrombotics: safe or sorry? / 05.2013 / PubMed / Full text