Aging genes 1-2: различия между версиями

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* [[Aging genes 1-2‎‎|Genes with 1-2 publications]]
* [[Aging genes 1-2‎‎|Genes with 1-2 publications]]


==SOCS1==
==ABCA1==


* {{medline-title
* {{medline-title
|title=Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus.
|title=Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension.
|date=06.2019
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30656452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109455
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0607-9
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.08.027
}}
}}
* {{medline-title
* {{medline-title
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.
|date=28.10.2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770
}}
}}
==ATG9A==
==ACACA==


* {{medline-title
* {{medline-title
|title=[[SIRT1]] protects cochlear hair cell and delays age-related hearing loss via autophagy.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=08.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.04.003
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
* {{medline-title
* {{medline-title
|title=Activation of miR-34a impairs autophagic flux and promotes cochlear cell death via repressing [[ATG9A]]: implications for age-related hearing loss.
|title=GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling.
|date=05.10.2017
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28981097
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29694926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680584
|full-text-url=https://sci-hub.do/10.1016/j.bone.2018.04.014
}}
}}
==LAT2==
==ACAT1==


* {{medline-title
* {{medline-title
|title=Blood glucose, amino acid profiles and nutrient transporter gene expressions in the small intestine of low and normal birthweight piglets during the early suckling period.
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|date=05.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971346
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|full-text-url=https://sci-hub.do/10.1016/j.tvjl.2019.02.006
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
}}
}}
* {{medline-title
* {{medline-title
|title=Skeletal muscle: from birth to old age, routes to mechanical and metabolic failure.
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
|date=2017
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29099099
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185
|full-text-url=https://sci-hub.do/10.24875/GMM.17000008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823
}}
}}
==ID1==
==ACOX1==


* {{medline-title
* {{medline-title
|title=Commentary on Some Recent Theses Relevant to Combating Aging: April 2019.
|title=Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes.
|date=04.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30957657
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677513
|full-text-url=https://sci-hub.do/10.1089/rej.2019.2201
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2019.01.005
}}
}}
* {{medline-title
* {{medline-title
|title=ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
|title=Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging.
|date=12.09.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847931
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765501
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603998
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889864
}}
}}
==OAT==
==ACTA1==


* {{medline-title
* {{medline-title
|title=Opioid agonist treatment reduces losses in quality of life and quality-adjusted life expectancy in heroin users: Evidence from real world data.
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle.
|date=01.08.2019
|date=15.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562
|full-text-url=https://sci-hub.do/10.1016/j.drugalcdep.2019.05.003
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004
}}
}}
* {{medline-title
* {{medline-title
|title=Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats.
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
|date=02.2019
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712161
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00663-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823
}}
}}
==ERBB2==
==ACTB==


* {{medline-title
* {{medline-title
|title=The biological age linked to oxidative stress modifies breast cancer aggressiveness.
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=20.05.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29550329
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.03.012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of human age-associated gene co-expressions in functional modules using liquid association.
|title=WNT-activated bone grafts repair osteonecrotic lesions in aged animals.
|date=02.01.2018
|date=27.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416677
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29079746
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660190
}}
}}
==NDNF==
==ADAM17==


* {{medline-title
* {{medline-title
|title=Effect of neuron-derived neurotrophic factor on rejuvenation of human adipose-derived stem cells for cardiac repair after myocardial infarction.
|title=ACE2/[[ADAM17]]/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19.
|date=09.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287219
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575774
}}
}}
* {{medline-title
* {{medline-title
|title=Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=12.2017
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30062183
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==NECTIN2==
==ADH5==


* {{medline-title
* {{medline-title
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|title=Can Serum Nitrosoproteome Predict Longevity of Aged Women?
|date=08.10.2018
|date=27.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33260845
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731247
}}
}}
* {{medline-title
* {{medline-title
|title=Apolipoprotein E region molecular signatures of Alzheimer's disease.
|title=Denitrosylate and live longer: how [[ADH5]]/GSNOR links mitophagy to aging.
|date=08.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797398
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30029585
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103690
}}
}}
==NDUFB8==
==AGER==


* {{medline-title
* {{medline-title
|title=Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats.
|title=Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model.
|date=23.05.2018
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29882895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31575929
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773724
}}
}}
* {{medline-title
* {{medline-title
|title=Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions.
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|date=06.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29802507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060193
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
}}
}}
==HSF2==
==AGO2==


* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability.
|date=15.04.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072
}}
}}
* {{medline-title
* {{medline-title
|title=Nutrition and water temperature regulate the expression of heat-shock proteins in golden pompano larvae (Trachinotus ovata, Limmaeus 1758).
|title=miRNA processing gene polymorphisms, blood DNA methylation age and long-term ambient PM  exposure in elderly men.
|date=04.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30397841
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29106301
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0578-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704092
}}
}}
==IQGAP1==
==AGT==


* {{medline-title
* {{medline-title
|title=[[IQGAP1]]-dysfunction leads to induction of senescence in human vascular smooth muscle cells.
|title=SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence.
|date=09.2020
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592713
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441382
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111295
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469683
}}
}}
* {{medline-title
* {{medline-title
|title=Hyaluronan-binding protein 1 (HABP1) overexpression triggers induction of senescence in fibroblasts cells.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=06.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32068317
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://sci-hub.do/10.1002/cbin.11326
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
==PAK1==
==ALKBH8==


* {{medline-title
* {{medline-title
|title=1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating [[PAK1]] at nM levels.
|title=Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming .
|date=2018
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765888
|full-text-url=https://sci-hub.do/10.5582/ddt.2018.01018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904832
}}
}}
* {{medline-title
* {{medline-title
|title=From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic [[PAK1]]-blockers/longevity-promoters for cancer therapy.
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|date=15.12.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814374
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|full-text-url=https://sci-hub.do/10.1016/j.ejmech.2017.07.043
 
}}
}}
==GNRH1==
==AMT==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=A multi-method comparison of autobiographical memory impairments amongst younger and older adults.
|date=15.11.2018
|date=12.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162531
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1080/13607863.2020.1729338
}}
}}
* {{medline-title
* {{medline-title
|title=Elucidating the genetic architecture of reproductive ageing in the Japanese population.
|title=Autobiographical Memory From Different Life Stages in Individuals With Obstructive Sleep Apnea.
|date=17.05.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29773799
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696518
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958096
|full-text-url=https://sci-hub.do/10.1017/S1355617718001091
}}
}}
==SORL1==
==ANGPTL2==


* {{medline-title
* {{medline-title
|title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.
|title=Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study.
|date=05.2019
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706571
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31840173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608707
|full-text-url=https://sci-hub.do/10.1093/ndt/gfz236
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.
|title=Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice.
|date=2018
|date=02.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29191837
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798292
}}
}}
==CISD2==
==ANK1==


* {{medline-title
* {{medline-title
|title=[[CISD2]] Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells-As a Potential Therapeutic Target for Neurodegenerative Dementia.
|title=Alzheimer's Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in [i]Drosophila[/i].
|date=2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33005144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31244615
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581016
}}
}}
* {{medline-title
* {{medline-title
|title=Protective Effects of [[CISD2]] and Influence of Curcumin on [[CISD2]] Expression in Aged Animals and Inflammatory Cell Model.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=25.03.2019
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30934593
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==MAPKAPK2==
==APOA5==


* {{medline-title
* {{medline-title
|title=Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks.
|title=Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.
|date=03.12.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31801093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30700132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399473
}}
}}
* {{medline-title
* {{medline-title
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|title=Longitudinal interaction between [[APOA5]] -1131T>C and overweight in the acceleration of age-related increase in arterial stiffness through the regulation of circulating triglycerides.
|date=07.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451986
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
|full-text-url=https://sci-hub.do/10.1038/s41440-018-0137-y
}}
}}
==RPS6==
==APPL2==


* {{medline-title
* {{medline-title
|title=Regulation of Amino Acid Transporters and Sensors in Response to a High protein Diet: A Randomized Controlled Trial in Elderly Men.
|title=The reversal effect of physical exercise on aging-related increases in [[APPL2]] content in skeletal muscle.
|date=2019
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30932134
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30189216
|full-text-url=https://sci-hub.do/10.1007/s12603-019-1171-4
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2018.09.006
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107.
|title=Adaptor Protein [[APPL2]] Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor.
|date=08.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28965332
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0785-y
}}
}}
==NNMT==
==AQP1==


* {{medline-title
* {{medline-title
|title=Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle.
|title=Blue Light Induces Down-Regulation of Aquaporin 1, 3, and 9 in Human Keratinocytes.
|date=05.2019
|date=03.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400272
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469996
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262559
}}
}}
* {{medline-title
* {{medline-title
|title=Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy.
|title=[Age-related changes of water transport by corneal endothelial cells in rats.]
|date=09.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30192747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322730
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191153
 
}}
}}
==SPARCL1==
==AQP3==


* {{medline-title
* {{medline-title
|title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment.
|title=Transbuccal platform for delivery of lipogenic actives to facial skin: Because fat matters.
|date=18.06.2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592290
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664
|full-text-url=https://sci-hub.do/10.1002/term.3087
}}
}}
* {{medline-title
* {{medline-title
|title=[[SPARCL1]] Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging.
|title=[Age-related changes of water transport by corneal endothelial cells in rats.]
|date=2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154276
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322730
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934753
 
}}
}}
==IRF7==
==AREG==


* {{medline-title
* {{medline-title
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|title=Targeting amphiregulin ([[AREG]]) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
|date=14.01.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31493351
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826133
}}
}}
* {{medline-title
* {{medline-title
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|date=06.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
}}
}}
==RGN==
==ARID1A==


* {{medline-title
* {{medline-title
|title=Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04.
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|date=2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29675370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902356
|full-text-url=https://sci-hub.do/10.1002/path.5314
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of supplementation of recombinant Regucalcin in extender on cryopreservation of spermatozoa of water buffalo (Bubalus bubalis).
|title=[[ARID1A]] suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[[[CDKN2A]]]] regulatory axis.
|date=11.2017
|date=18.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782859
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942143
|full-text-url=https://sci-hub.do/10.1002/mrd.22873
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.099
}}
}}
==MCM7==
==ATG12==


* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=27.07.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=08.01.2018
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==AQP1==
==ATG3==


* {{medline-title
* {{medline-title
|title=Blue Light Induces Down-Regulation of Aquaporin 1, 3, and 9 in Human Keratinocytes.
|title=Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells.
|date=03.11.2018
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400272
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32244623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235898
}}
}}
* {{medline-title
* {{medline-title
|title=[Age-related changes of water transport by corneal endothelial cells in rats.]
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=2017
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322730
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==EN1==
==ATG9A==


* {{medline-title
* {{medline-title
|title=Electrochemically detecting DNA methylation in the [[EN1]] gene promoter: implications for understanding ageing and disease.
|title=[[SIRT1]] protects cochlear hair cell and delays age-related hearing loss via autophagy.
|date=27.11.2020
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33135722
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670582
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.04.003
}}
}}
* {{medline-title
* {{medline-title
|title=The role of DNA methylation in ageing and cancer.
|title=Activation of miR-34a impairs autophagic flux and promotes cochlear cell death via repressing [[ATG9A]]: implications for age-related hearing loss.
|date=11.2018
|date=05.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29708096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28981097
|full-text-url=https://sci-hub.do/10.1017/S0029665118000150
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680584
}}
}}
==PPID==
==ATP7A==


* {{medline-title
* {{medline-title
|title=Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population.
|title=Adipocyte-specific disruption of ATPase copper transporting α in mice accelerates lipoatrophy.
|date=03.2020
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32058159
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396659
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2020.110013
|full-text-url=https://sci-hub.do/10.1007/s00125-019-4966-2
}}
}}
* {{medline-title
* {{medline-title
|title=Epidemiology of pituitary pars intermedia dysfunction: A systematic literature review of clinical presentation, disease prevalence and risk factors.
|title=TAp73 regulates [[ATP7A]]: possible implications for ageing-related diseases.
|date=05.2018
|date=08.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29704935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530920
|full-text-url=https://sci-hub.do/10.1016/j.tvjl.2018.03.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326685
}}
}}
==ADH5==
==B2M==


* {{medline-title
* {{medline-title
|title=Can Serum Nitrosoproteome Predict Longevity of Aged Women?
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes.
|date=27.11.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33260845
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468
}}
}}
* {{medline-title
* {{medline-title
|title=Denitrosylate and live longer: how [[ADH5]]/GSNOR links mitophagy to aging.
|title=Association between serum β2-microglobulin levels and frailty in an elderly Chinese population: results from RuLAS.
|date=2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30029585
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103690
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652941
}}
}}
==LTB==
==B4GALT1==


* {{medline-title
* {{medline-title
|title=Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA + DHA.
|title=Expression of β-1,4-galactosyltransferases during Aging in Caenorhabditis elegans.
|date=06.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30535619
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33171474
|full-text-url=https://sci-hub.do/10.1007/s10753-018-0949-6
|full-text-url=https://sci-hub.do/10.1159/000510722
}}
}}
* {{medline-title
* {{medline-title
|title=Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis.
|title=Glycobiology of Aging.
|date=11.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803166
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30779020
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.07.043
|full-text-url=https://sci-hub.do/10.1007/978-981-13-2835-0_17
}}
}}
==TRH==
==BAK1==


* {{medline-title
* {{medline-title
|title=Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats.
|title=Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon.
|date=15.03.2018
|date=23.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29305326
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32710818
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2017.12.029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529960
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of dietary carbohydrates and time of year on ACTH and cortisol concentrations in adult and aged horses.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=04.2018
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195115
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2017.10.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==GLS==
==BCL6==


* {{medline-title
* {{medline-title
|title=Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography.
|title=Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation.
|date=15.07.2018
|date=01.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29784576
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32452837
|full-text-url=https://sci-hub.do/10.1016/j.amjcard.2018.03.355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324201
}}
}}
* {{medline-title
* {{medline-title
|title=Future Perspectives for Management of Stage A Heart Failure.
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|date=01.07.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731506
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055033
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
}}
}}
==CLC==
==BECN1==


* {{medline-title
* {{medline-title
|title=Impact of Intervention to Improve Nursing Home Resident-Staff Interactions and Engagement.
|title=Calpain-dependent Beclin1 cleavage stimulates senescence-associated cell death in HT22 hippocampal cells under the oxidative stress conditions.
|date=13.07.2018
|date=14.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718195
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30807795
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455946
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2019.02.036
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of cholesterol loaded cyclodextrin on semen cryopreservation of Aksaray Malakli shepherd dogs of different ages.
|title=Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-[[ULK1]] signaling pathway.
|date=06.2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29699920
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344647
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2018.04.068
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810242
}}
}}
==RAG1==
==BGN==


* {{medline-title
* {{medline-title
|title=T cell senescence accelerates Angiotensin II-induced target organ damage.
|title=Alterations of local functional connectivity in lifespan: A resting-state fMRI study.
|date=12.02.2020
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32049355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32462815
|full-text-url=https://sci-hub.do/10.1093/cvr/cvaa032
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375100
}}
}}
* {{medline-title
* {{medline-title
|title=Aged murine hematopoietic stem cells drive aging-associated immune remodeling.
|title=Exploring variability in basal ganglia connectivity with functional MRI in healthy aging.
|date=09.08.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891535
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29442271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137572
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302142
}}
}}
==HLA-C==
==BIN1==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.
|date=10.2019
|date=20.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866
}}
}}
* {{medline-title
* {{medline-title
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=2017
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
==WFS1==
==BMF==


* {{medline-title
* {{medline-title
|title=Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila.
|title=lncRNA-ES3/miR-34c-5p/[[BMF]] axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs.
|date=01.2018
|date=17.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29357349
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794194
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366973
}}
}}
* {{medline-title
* {{medline-title
|title=A nonsynonymous mutation in the [[WFS1]] gene in a Finnish family with age-related hearing impairment.
|title=Aging, hematopoiesis, and the myelodysplastic syndromes.
|date=11.2017
|date=08.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28974383
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29222239
|full-text-url=https://sci-hub.do/10.1016/j.heares.2017.09.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142578
}}
}}
==PLIN2==
==BMP15==


* {{medline-title
* {{medline-title
|title=Cardiac overexpression of perilipin 2 induces atrial steatosis, connexin 43 remodeling, and atrial fibrillation in aged mice.
|title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro.
|date=01.12.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31661297
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957375
|full-text-url=https://sci-hub.do/10.1002/mrd.23079
}}
}}
* {{medline-title
* {{medline-title
|title=[[HDAC6]] Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of [[PLIN2]] in Drosophila.
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|date=09.10.2017
|date=18.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28966044
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2017.09.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
}}
}}
==CCL24==
==BNIP3==


* {{medline-title
* {{medline-title
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training.
|date=2019
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857
}}
}}
* {{medline-title
* {{medline-title
|title=Anserine/Carnosine Supplementation Suppresses the Expression of the Inflammatory Chemokine [[CCL24]] in Peripheral Blood Mononuclear Cells from Elderly People.
|title=Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training.
|date=31.10.2017
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088099
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030137
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707671
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.011
}}
}}
==TAS2R16==
==BTK==


* {{medline-title
* {{medline-title
|title=Taste receptor polymorphisms and longevity: a systematic review and meta-analysis.
|title=Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition.
|date=10.11.2020
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33170488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31736210
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01745-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974713
}}
}}
* {{medline-title
* {{medline-title
|title=Taste receptors, innate immunity and longevity: the case of [[TAS2R16]] gene.
|title=[[BTK]] suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling.
|date=2019
|date=22.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30833980
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28915637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387736
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593608
}}
}}
==B4GALT1==
==C9orf72==


* {{medline-title
* {{medline-title
|title=Expression of β-1,4-galactosyltransferases during Aging in Caenorhabditis elegans.
|title=Carriership of two copies of [[C9orf72]] hexanucleotide repeat intermediate-length alleles is a risk factor for ALS in the Finnish population.
|date=2020
|date=09.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33171474
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168078
|full-text-url=https://sci-hub.do/10.1159/000510722
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654028
}}
}}
* {{medline-title
* {{medline-title
|title=Glycobiology of Aging.
|title=[[C9]]orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons.
|date=2018
|date=29.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30779020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037833
|full-text-url=https://sci-hub.do/10.1007/978-981-13-2835-0_17
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705968
}}
}}
==FGFR4==
==CAST==


* {{medline-title
* {{medline-title
|title=[[FGFR4]] Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer.
|title=Cytomatrix proteins [[CAST]] and ELKS regulate retinal photoreceptor development and maintenance.
|date=14.10.2020
|date=05.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066597
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30190286
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602396
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219712
}}
}}
* {{medline-title
* {{medline-title
|title=The Klotho proteins in health and disease.
|title=Short Telomeres Induce p53 and Autophagy and Modulate Age-Associated Changes in Cardiac Progenitor Cell Fate.
|date=01.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29441645
|full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992026
}}
}}
==NAV2==
==CBL==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Effects of cerebrolysin on nerve growth factor system in the aging rat brain.
|date=10.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701766
}}
}}
* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Skeletal Muscle CAP Expression Increases after Dietary Restriction and Aerobic Training in Women with a History of Gestational Diabetes.
|date=07.2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28989819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628746
}}
}}
==ANK1==
==CCL17==


* {{medline-title
* {{medline-title
|title=Alzheimer's Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in [i]Drosophila[/i].
|title=Aging and chronic high-fat feeding negatively affects kidney size, function, and gene expression in CTRP1-deficient mice.
|date=2019
|date=21.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31244615
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33085906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581016
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00139.2020
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism.
|date=25.07.2018
|date=21.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237
}}
}}
==COL3A1==
==CCL20==


* {{medline-title
* {{medline-title
|title=Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season.
|title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors.
|date=21.12.2019
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31864349
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925900
|full-text-url=https://sci-hub.do/10.1016/j.antiviral.2020.104784
}}
}}
* {{medline-title
* {{medline-title
|title=Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts.
|title=Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly.
|date=06.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29193757
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553930
|full-text-url=https://sci-hub.do/10.1002/mnfr.201700307
}}
}}
==ATP7A==
==CCL21==


* {{medline-title
* {{medline-title
|title=Adipocyte-specific disruption of ATPase copper transporting α in mice accelerates lipoatrophy.
|title=[[CCL21]]/[[CCR7]] axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
|date=12.2019
|date=26.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396659
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30914733
|full-text-url=https://sci-hub.do/10.1007/s00125-019-4966-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435673
}}
}}
* {{medline-title
* {{medline-title
|title=TAp73 regulates [[ATP7A]]: possible implications for ageing-related diseases.
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|date=08.12.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30530920
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
}}
}}
==TPO==
==CCL24==


* {{medline-title
* {{medline-title
|title=Megakaryocytes promote osteoclastogenesis in aging.
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|date=07.07.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
}}
}}
* {{medline-title
* {{medline-title
|title=To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex-independent) NOD.H2  mice.
|title=Anserine/Carnosine Supplementation Suppresses the Expression of the Inflammatory Chemokine [[CCL24]] in Peripheral Blood Mononuclear Cells from Elderly People.
|date=04.2019
|date=31.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566234
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088099
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707671
}}
}}
==HAS1==
==CCN3==


* {{medline-title
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|title=[[CCN3]] Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta.
|date=20.06.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304321
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701218
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts.
|title=[[CCN3]] (NOV) Drives Degradative Changes in Aging Articular Cartilage.
|date=01.2018
|date=13.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066270
|full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593953
}}
}}
==TIMELESS==
==CCNG2==


* {{medline-title
* {{medline-title
|title=Loss of circadian protein [[TIMELESS]] accelerates the progression of cellular senescence.
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|date=18.09.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30100061
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.040
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
}}
}}
* {{medline-title
* {{medline-title
|title=Clock gene expression and locomotor activity predict death in the last days of life in Drosophila melanogaster.
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|date=09.08.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30093652
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085321
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
}}
}}
==PROC==
==CCR6==


* {{medline-title
* {{medline-title
|title=Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation.
|title=Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells.
|date=15.04.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696983
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157190
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of feeding frequency of an elevated plane of milk replacer and calf age on behavior, and glucose and insulin kinetics in male Holstein calves.
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|date=07.2019
|date=19.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30419975
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|full-text-url=https://sci-hub.do/10.1017/S175173111800294X
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
}}
}}
==FLT1==
==CD22==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=[[CD22]] blockade restores homeostatic microglial phagocytosis in ageing brains.
|date=15.11.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944478
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6574119
}}
}}
* {{medline-title
* {{medline-title
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|title=Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves.
|date=08.10.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
|full-text-url=https://sci-hub.do/10.24425/119039
}}
}}
==IGFBP1==
==CDK1==


* {{medline-title
* {{medline-title
|title=Role of [[IGFBP1]] in the senescence of vascular endothelial cells and severity of aging‑related coronary atherosclerosis.
|title=MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging.
|date=11.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31848878
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777673
|full-text-url=https://sci-hub.do/10.1007/s12015-019-09924-0
}}
}}
* {{medline-title
* {{medline-title
|title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age.
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|date=04.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
}}
}}
==NLRC4==
==CDKN2B==


* {{medline-title
* {{medline-title
|title=Hyperglycemia-induced inflamm-aging accelerates gingival senescence via [[NLRC4]] phosphorylation.
|title=Molecular Genetics and Functional Analysis Implicate [i][[CDKN2B]]AS1-[[CDKN2B]][/i] Involvement in POAG Pathogenesis.
|date=06.12.2019
|date=21.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31676687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32825664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564117
}}
}}
* {{medline-title
* {{medline-title
|title=Contribution of the inflammasome to inflammaging.
|title=Interference of the long noncoding RNA [[CDKN2B]]-AS1 upregulates miR-181a-5p/TGFβI axis to restrain the metastasis and promote apoptosis and senescence of cervical cancer cells.
|date=2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30473634
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884187
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240324
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488111
}}
}}
==PTBP1==
==CFD==


* {{medline-title
* {{medline-title
|title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence.
|title=Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D.
|date=11.12.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026383
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850482
}}
}}
* {{medline-title
* {{medline-title
|title=[[PTBP1]]-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.
|title=New horizons in the compression of functional decline.
|date=09.07.2018
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990503
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165372
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201827
}}
}}
==LSR==
==CHI3L1==


* {{medline-title
* {{medline-title
|title=Age-related changes in regiospecific expression of Lipolysis Stimulated Receptor ([[LSR]]) in mice brain.
|title=Postsynaptic damage and microglial activation in AD patients could be linked CXCR4/CXCL12 expression levels.
|date=2019
|date=15.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31233547
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32949560
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590887
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2020.147127
}}
}}
* {{medline-title
* {{medline-title
|title=Discriminating Alzheimer's disease progression using a new hippocampal marker from T1-weighted MRI: The local surface roughness.
|title=Sex difference in [[CHI3L1]] expression levels in human brain aging and in Alzheimer's disease.
|date=01.04.2019
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451343
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247206
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865478
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2019.146305
}}
}}
==MLH1==
==CHM==


* {{medline-title
* {{medline-title
|title=The somatic mutation landscape of the human body.
|title=[Molecular regulative mechanisms of aging and interventional effects of Chinese herbal medicine].
|date=24.12.2019
|date=08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31874648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171222
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930685
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20170731.001
}}
}}
* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=[Molecular mechanisms of autophagy in regulating renal aging and interventional effects of Chinese herbal medicine].
|date=25.02.2019
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28929674
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://sci-hub.do/10.4268/cjcmm20162105
}}
}}
==DISC1==
==CISD2==


* {{medline-title
* {{medline-title
|title=Age-Related Changes in Topological Degradation of White Matter Networks and Gene Expression in Chronic Schizophrenia.
|title=[[CISD2]] Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells-As a Potential Therapeutic Target for Neurodegenerative Dementia.
|date=11.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28946750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33005144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695754
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479185
}}
}}
* {{medline-title
* {{medline-title
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|title=Protective Effects of [[CISD2]] and Influence of Curcumin on [[CISD2]] Expression in Aged Animals and Inflammatory Cell Model.
|date=19.09.2017
|date=25.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30934593
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470567
}}
}}
==RAN==
==CLC==


* {{medline-title
* {{medline-title
|title=Rapid automatized naming ([[RAN]]): effects of aging on a predictor of reading skill.
|title=Impact of Intervention to Improve Nursing Home Resident-Staff Interactions and Engagement.
|date=17.08.2020
|date=13.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32799742
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29718195
|full-text-url=https://sci-hub.do/10.1080/13825585.2020.1806987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455946
}}
}}
* {{medline-title
* {{medline-title
|title=SCA8 [[RAN]] polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F.
|title=Effect of cholesterol loaded cyclodextrin on semen cryopreservation of Aksaray Malakli shepherd dogs of different ages.
|date=01.10.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29699920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166133
|full-text-url=https://sci-hub.do/10.1016/j.anireprosci.2018.04.068
}}
}}
==SRR==
==CLPP==


* {{medline-title
* {{medline-title
|title=Mediterranean diet and its components in relation to all-cause mortality: meta-analysis.
|title=Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging.
|date=11.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30401007
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30691623
|full-text-url=https://sci-hub.do/10.1017/S0007114518002593
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.11.048
}}
}}
* {{medline-title
* {{medline-title
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|title=Mitochondrial unfolded protein response gene Clpp is required to maintain ovarian follicular reserve during aging, for oocyte competence, and development of pre-implantation embryos.
|date=2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29851234
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052477
}}
}}
==MIF==
==COL3A1==


* {{medline-title
* {{medline-title
|title=Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice.
|title=Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season.
|date=09.2019
|date=21.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31381889
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31864349
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718337
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925900
}}
}}
* {{medline-title
* {{medline-title
|title=Macrophage migration inhibitory factor knockdown inhibit viability and induce apoptosis of PVM/Ms.
|title=Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts.
|date=12.2017
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28990052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890563
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553930
}}
}}
==GSTA4==
==COPE==


* {{medline-title
* {{medline-title
|title=Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue.
|title=Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the [[COPE]]-study.
|date=02.2019
|date=09.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272897
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147053
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Falls self-efficacy and falls incidence in community-dwelling older people: the mediating role of coping.
|date=12.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29113615
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://sci-hub.do/10.1017/S1041610217002319
}}
}}
==MCM2==
==CPD==


* {{medline-title
* {{medline-title
|title=Trophoblast type-specific expression of senescence markers in the human placenta.
|title=Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease.
|date=15.09.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327484
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470706
|full-text-url=https://sci-hub.do/10.1016/j.placenta.2019.06.377
|full-text-url=https://sci-hub.do/10.1007/s00391-018-1377-9
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=What Do Clinical Supervisors Require to Teach Residents in Family Medicine How to Care for Seniors?
|date=27.07.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29310735
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://sci-hub.do/10.1017/S0714980817000460
}}
}}
==RNF8==
==CPE==


* {{medline-title
* {{medline-title
|title=Expression of [[RNF8]] on cochlear apoptosis and aging in mice of different ages.
|title=Cross-Sectional and Cumulative Longitudinal Central Nervous System Penetration Effectiveness Scores Are Not Associated With Neurocognitive Impairment in a Well Treated Aging Human Immunodeficiency Virus-Positive Population in Switzerland.
|date=03-Apr,.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915826
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304188
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612860
}}
}}
* {{medline-title
* {{medline-title
|title=Function of RAD6B and [[RNF8]] in spermatogenesis.
|title=COCOA (Theobroma cacao) Polyphenol-Rich Extract Increases the Chronological Lifespan of Saccharomyces cerevisiae.
|date=2018
|date=2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825854
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29240368
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884393
 
}}
}}
==NOTCH3==
==CPQ==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=A Spanish Adaptation of the Computer and Mobile Device Proficiency Questionnaires ([[CPQ]] and MDPQ) for Older Adults.
|date=16.08.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31214066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554441
}}
}}
* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Protective Effect of Semisynthetic and Natural Flavonoid on Aged Rat Microglia-enriched Cultures.
|date=06.2018
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31230229
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://sci-hub.do/10.1007/s12640-019-00071-5
}}
}}
==AGO2==
==CRABP2==


* {{medline-title
* {{medline-title
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability.
|title=Preconception resveratrol intake against infertility: Friend or foe?
|date=06.2018
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32273814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138940
}}
}}
* {{medline-title
* {{medline-title
|title=miRNA processing gene polymorphisms, blood DNA methylation age and long-term ambient PM  exposure in elderly men.
|title=Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females.
|date=12.2017
|date=31.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29106301
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089527
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663855
}}
}}
==LATS2==
==CSRP1==


* {{medline-title
* {{medline-title
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|title=[[FOXO3]], a Molecular Search for the Fountain of Youth.
|date=25.06.2019
|date=07.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30849363
 
|full-text-url=https://sci-hub.do/10.1016/j.stem.2019.02.008
}}
}}
* {{medline-title
* {{medline-title
|title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis.
|title=[[FOXO3]]-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration.
|date=03.2019
|date=07.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661960
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607
|full-text-url=https://sci-hub.do/10.1016/j.stem.2018.12.002
}}
}}
==CTLA4==
==CTLA4==
Строка 889: Строка 889:
|full-text-url=https://sci-hub.do/10.1016/j.bulcan.2018.10.004
|full-text-url=https://sci-hub.do/10.1016/j.bulcan.2018.10.004
}}
}}
==SESN2==
==CXCL11==


* {{medline-title
* {{medline-title
|title=Copy Number Alterations in Papillary Thyroid Carcinomas: Does Loss of [i][[SESN2]][/i] Have a Role in Age-related Different Prognoses?
|title=Endothelial cells under therapy-induced senescence secrete [[CXCL11]], which increases aggressiveness of breast cancer cells.
|date=09-10.2020
|date=10.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32859642
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659248
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472442
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2020.06.019
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea.
|title=Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity.
|date=11.10.2017
|date=13.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28818524
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30867067
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605466
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417215
}}
}}
==ZEB1==
==CXCL5==


* {{medline-title
* {{medline-title
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|title=Hassall's corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus.
|date=12.2018
|date=05.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534943
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
|full-text-url=https://sci-hub.do/10.1093/intimm/dxy073
}}
}}
* {{medline-title
* {{medline-title
|title=Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating [[DNMT1]] via [[ZEB1]].
|title=Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age.
|date=16.02.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29466247
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891542
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105902
}}
}}
==CLPP==
==CYLD==


* {{medline-title
* {{medline-title
|title=Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging.
|title=Premature aging and cancer development in transgenic mice lacking functional [[CYLD]].
|date=02.2019
|date=10.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30691623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30631004
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.11.048
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339805
}}
}}
* {{medline-title
* {{medline-title
|title=Mitochondrial unfolded protein response gene Clpp is required to maintain ovarian follicular reserve during aging, for oocyte competence, and development of pre-implantation embryos.
|title=Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis.
|date=08.2018
|date=22.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29851234
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052477
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.12.025
}}
}}
==BNIP3==
==CYP1A1==


* {{medline-title
* {{medline-title
|title=Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training.
|title=Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population.
|date=01.10.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31306740
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31522824
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707857
|full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2019.08.010
}}
}}
* {{medline-title
* {{medline-title
|title=Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training.
|title=Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in [[CYP1A1]]-overexpressing breast cancer cells.
|date=01.10.2018
|date=15.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30030137
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448188
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.07.011
|full-text-url=https://sci-hub.do/10.1016/j.bmc.2018.11.013
}}
}}
==CSRP1==
==CYP1A2==


* {{medline-title
* {{medline-title
|title=[[FOXO3]], a Molecular Search for the Fountain of Youth.
|title=Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of [[CYP1A2]]-Mediated Pharmacokinetics in Young and Elderly Chinese Adults.
|date=07.03.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30849363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767128
|full-text-url=https://sci-hub.do/10.1016/j.stem.2019.02.008
|full-text-url=https://sci-hub.do/10.1007/s40262-019-00737-5
}}
}}
* {{medline-title
* {{medline-title
|title=[[FOXO3]]-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration.
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
|date=07.03.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661960
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475
|full-text-url=https://sci-hub.do/10.1016/j.stem.2018.12.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442
}}
}}
==BCL6==
==CYP27B1==


* {{medline-title
* {{medline-title
|title=Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation.
|title=Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance.
|date=01.07.2020
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32452837
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955863
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693043
}}
}}
* {{medline-title
* {{medline-title
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|title=Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism.
|date=08.2019
|date=22.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823
}}
}}
==GRK5==
==CYP2D6==


* {{medline-title
* {{medline-title
|title=Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone.
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|date=01.05.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31043680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494869
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
}}
}}
* {{medline-title
* {{medline-title
|title=[[GRK5]] - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders.
|title=[Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug].
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30618771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30175758
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304357
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00114
}}
}}
==MCL1==
==CYP3A4==


* {{medline-title
* {{medline-title
|title=[[MCL1]] gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway.
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|date=01.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30296359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|full-text-url=https://sci-hub.do/10.1002/iub.1944
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
}}
}}
* {{medline-title
* {{medline-title
|title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia.
|date=10.08.2017
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442
}}
}}
==COPE==
==CYP7A1==


* {{medline-title
* {{medline-title
|title=Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the [[COPE]]-study.
|title=Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats.
|date=09.04.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396457
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147053
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681801
}}
}}
* {{medline-title
* {{medline-title
|title=Falls self-efficacy and falls incidence in community-dwelling older people: the mediating role of coping.
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio).
|date=05.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29113615
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246
|full-text-url=https://sci-hub.do/10.1017/S1041610217002319
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128
}}
}}
==L1CAM==
==DAO==


* {{medline-title
* {{medline-title
|title=Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression.
|title=Age- and gender-dependent D-amino acid oxidase activity in mouse brain and peripheral tissues: implication for aging and neurodegeneration.
|date=12.09.2019
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31510944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30938755
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739972
|full-text-url=https://sci-hub.do/10.1093/jb/mvz025
}}
}}
* {{medline-title
* {{medline-title
|title=Induction, regulation and roles of neural adhesion molecule [[L1CAM]] in cellular senescence.
|title=Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging.
|date=28.03.2018
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615539
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29093468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665939
}}
}}
==MMP3==
==DAPK1==


* {{medline-title
* {{medline-title
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=14.11.2017
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
* {{medline-title
* {{medline-title
|title=Identification of a pyridine derivative inducing senescence in ovarian cancer cell lines via P21 activation.
|title=Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of [[DAPK1]] in Aging.
|date=05.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143360
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30120735
|full-text-url=https://sci-hub.do/10.1111/1440-1681.12891
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1312-5
}}
}}
==INSL3==
==DDB1==


* {{medline-title
* {{medline-title
|title=Effect of Thyroxine Replacement on Leydig Cell and Sertoli Cell Function in Men with Hypothyroidism.
|title=DCAF1 regulates Treg senescence via the ROS axis during immunological aging.
|date=05-06.2020
|date=02.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33083267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32730228
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598062
}}
}}
* {{medline-title
* {{medline-title
|title=Age related and seasonal changes of plasma concentrations of insulin-like peptide 3 and testosterone from birth to early-puberty in Thoroughbred male horses.
|title=Deletion of [[DDB1]]- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice.
|date=01.07.2019
|date=15.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31029851
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907856
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2019.04.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003934
}}
}}
==CYP1A1==
==DDX41==


* {{medline-title
* {{medline-title
|title=Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population.
|title=Salidroside influences the cellular cross-talk of human fetal lung diploid fibroblasts: A proteomic approach.
|date=10.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31522824
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29329019
|full-text-url=https://sci-hub.do/10.1016/j.jdermsci.2019.08.010
|full-text-url=https://sci-hub.do/10.1016/j.etap.2018.01.001
}}
}}
* {{medline-title
* {{medline-title
|title=Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in [[CYP1A1]]-overexpressing breast cancer cells.
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|date=15.12.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|full-text-url=https://sci-hub.do/10.1016/j.bmc.2018.11.013
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
}}
}}
==POSTN==
==DDX58==


* {{medline-title
* {{medline-title
|title=A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals [[POSTN]] As a New Element in Proline Metabolic Disorder.
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|date=12.2018
|date=14.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284769
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Age-associated mRNA expression changes in bovine endometrial cells in vitro.
|date=02.2018
|date=14.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28806906
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556672
}}
}}
==HLA-B==
==DEGS1==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=[Frailty: Prevalence in the Resident Population of Germany 70 - 79 Years of Age - a Population-Based Approach].
|date=10.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29156480
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.1055/s-0043-105841
}}
}}
* {{medline-title
* {{medline-title
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|title=Physical exercise and cognitive function across the life span: Results of a nationwide population-based study.
|date=2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28919495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
|full-text-url=https://sci-hub.do/10.1016/j.jsams.2017.08.022
}}
}}
==IRF4==
==DICER1==


* {{medline-title
* {{medline-title
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|title=[[DICER1]]: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging.
|date=08.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066587
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice.
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability.
|date=11.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28905935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072
}}
}}
==PLD2==
==DISC1==


* {{medline-title
* {{medline-title
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|title=Age-Related Changes in Topological Degradation of White Matter Networks and Gene Expression in Chronic Schizophrenia.
|date=08.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28946750
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695754
}}
}}
* {{medline-title
* {{medline-title
|title=Role of phospholipase D in the lifespan of Caenorhabditis elegans.
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|date=06.04.2018
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29622768
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
}}
}}
==IDE==
==DKC1==


* {{medline-title
* {{medline-title
|title=Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
|title=Successful liver transplantation in short telomere syndromes without bone marrow failure due to [[DKC1]] mutation.
|date=2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32538851
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32166868
|full-text-url=https://sci-hub.do/10.3233/JAD-200308
|full-text-url=https://sci-hub.do/10.1111/petr.13695
}}
}}
* {{medline-title
* {{medline-title
|title=Hyperinsulinemia is associated with increasing insulin secretion but not with decreasing insulin clearance in an age-related metabolic dysfunction mice model.
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|date=06.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30370604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|full-text-url=https://sci-hub.do/10.1002/jcp.27667
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
}}
}}
==NPR1==
==DLX5==


* {{medline-title
* {{medline-title
|title=The [[NPR1]]-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana.
|title=Inhibition of microRNA-27b-3p relieves osteoarthritis pain via regulation of KDM4B-dependent [[DLX5]].
|date=03.12.2020
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33270345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856377
|full-text-url=https://sci-hub.do/10.1111/jipb.13044
|full-text-url=https://sci-hub.do/10.1002/biof.1670
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis.
|title=Detection and evaluation of DNA methylation markers found at [[SCGN]] and [[KLF14]] loci to estimate human age.
|date=07.2020
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32540002
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854399
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2020.110472
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011
}}
}}
==CYP2D6==
==DRD3==


* {{medline-title
* {{medline-title
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|title=Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality.
|date=05.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30439596
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.10.012
}}
}}
* {{medline-title
* {{medline-title
|title=[Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug].
|title=Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.
|date=2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30175758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29637543
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00114
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105503
}}
}}
==PAPPA==
==DSP==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions.
|date=02.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247288
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754798
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease.
|date=12.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171
}}
}}
==ZC3H12A==
==DST==


* {{medline-title
* {{medline-title
|title=Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation.
|title=Ancestral germen/soma distinction in microbes: Expanding the disposable soma theory of aging to all unicellular lineages.
|date=12.2019
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31786670
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268207
|full-text-url=https://sci-hub.do/10.1007/s00109-019-01853-2
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101064
}}
}}
* {{medline-title
* {{medline-title
|title=Prediction and characterization of human ageing-related proteins by using machine learning.
|title=Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study.
|date=06.03.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29511309
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840292
|full-text-url=https://sci-hub.do/10.1111/jgs.16089
}}
}}
==NMNAT2==
==E2F2==


* {{medline-title
* {{medline-title
|title=[[NMNAT2]]-mediated NAD  generation is essential for quality control of aged oocytes.
|title=MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment.
|date=06.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909324
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896785
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052401
}}
}}
* {{medline-title
* {{medline-title
|title=Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.
|title=In situ regeneration of retinal pigment epithelium by gene transfer of [[E2F2]]: a potential strategy for treatment of macular degenerations.
|date=03.10.2017
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29188796
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640801
|full-text-url=https://sci-hub.do/10.1038/gt.2017.89
}}
}}
==BMF==
==EDARADD==


* {{medline-title
* {{medline-title
|title=lncRNA-ES3/miR-34c-5p/[[BMF]] axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs.
|title=Age prediction in living: Forensic epigenetic age estimation based on blood samples.
|date=17.01.2019
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366973
|full-text-url=https://sci-hub.do/10.1016/j.legalmed.2020.101763
}}
}}
* {{medline-title
* {{medline-title
|title=Aging, hematopoiesis, and the myelodysplastic syndromes.
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird.
|date=08.12.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29222239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723
}}
}}
==ACAT1==
==EN1==


* {{medline-title
* {{medline-title
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|title=Electrochemically detecting DNA methylation in the [[EN1]] gene promoter: implications for understanding ageing and disease.
|date=06.2019
|date=27.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33135722
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670582
}}
}}
* {{medline-title
* {{medline-title
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
|title=The role of DNA methylation in ageing and cancer.
|date=15.12.2017
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29708096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823
|full-text-url=https://sci-hub.do/10.1017/S0029665118000150
}}
}}
==CYLD==
==ERBB2==


* {{medline-title
* {{medline-title
|title=Premature aging and cancer development in transgenic mice lacking functional [[CYLD]].
|title=The biological age linked to oxidative stress modifies breast cancer aggressiveness.
|date=10.01.2019
|date=20.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30631004
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29550329
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339805
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.03.012
}}
}}
* {{medline-title
* {{medline-title
|title=Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis.
|title=Identification of human age-associated gene co-expressions in functional modules using liquid association.
|date=22.01.2019
|date=02.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416677
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.12.025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787419
}}
}}
==POT1==
==ETS1==


* {{medline-title
* {{medline-title
|title=MiR-185 targets [[POT1]] to induce telomere dysfunction and cellular senescence.
|title=The transcription factor [[ETS1]] promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1.
|date=18.07.2020
|date=06.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32687062
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31659122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425516
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901313
}}
}}
* {{medline-title
* {{medline-title
|title=Seryl tRNA synthetase cooperates with [[POT1]] to regulate telomere length and cellular senescence.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=2019
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31815007
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882858
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==CPQ==
==F7==


* {{medline-title
* {{medline-title
|title=A Spanish Adaptation of the Computer and Mobile Device Proficiency Questionnaires ([[CPQ]] and MDPQ) for Older Adults.
|title=The Pattern of Mu Rhythm Modulation During Emotional Destination Memory: Comparison Between Mild Cognitive Impairment Patients and Healthy Controls.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31214066
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524160
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554441
|full-text-url=https://sci-hub.do/10.3233/JAD-190311
}}
}}
* {{medline-title
* {{medline-title
|title=Protective Effect of Semisynthetic and Natural Flavonoid on Aged Rat Microglia-enriched Cultures.
|title=High levels of incidental physical activity are positively associated with cognition and EEG activity in aging.
|date=11.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31230229
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29370215
|full-text-url=https://sci-hub.do/10.1007/s12640-019-00071-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784952
}}
}}
==NRK==
==FAAH==


* {{medline-title
* {{medline-title
|title=[Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/[[ULK1]] signaling activation].
|title=Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice.
|date=03.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989992
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32095523
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20181205.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015690
}}
}}
* {{medline-title
* {{medline-title
|title=Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-[[ULK1]] signaling-mediated autophagy.
|title=Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan.
|date=24.12.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585174
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326678
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548519
}}
}}
==CCL20==
==FABP4==


* {{medline-title
* {{medline-title
|title=p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors.
|title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation.
|date=06.2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32272174
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239
|full-text-url=https://sci-hub.do/10.1016/j.antiviral.2020.104784
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly.
|title=Endothelial [[APLNR]] regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.
|date=02.2018
|date=13.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29193757
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904225
|full-text-url=https://sci-hub.do/10.1002/mnfr.201700307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703224
}}
}}
==YAP1==
==FANCD2==


* {{medline-title
* {{medline-title
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|title=TFG-maintaining stability of overlooked [[FANCD2]] confers early DNA-damage response.
|date=25.06.2019
|date=24.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099537
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655164
}}
}}
* {{medline-title
* {{medline-title
|title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis.
|title=[[FANCD2]] and DNA Damage.
|date=03.2019
|date=19.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578191
}}
}}
==CYP1A2==
==FGFR4==


* {{medline-title
* {{medline-title
|title=Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of [[CYP1A2]]-Mediated Pharmacokinetics in Young and Elderly Chinese Adults.
|title=[[FGFR4]] Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer.
|date=07.2019
|date=14.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767128
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066597
|full-text-url=https://sci-hub.do/10.1007/s40262-019-00737-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7602396
}}
}}
* {{medline-title
* {{medline-title
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
|title=The Klotho proteins in health and disease.
|date=12.2017
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30455427
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442
|full-text-url=https://sci-hub.do/10.1038/s41581-018-0078-3
}}
==ARID1A==
 
* {{medline-title
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|full-text-url=https://sci-hub.do/10.1002/path.5314
}}
* {{medline-title
|title=[[ARID1A]] suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[[[CDKN2A]]]] regulatory axis.
|date=18.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942143
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.09.099
}}
==CPD==
 
* {{medline-title
|title=Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470706
|full-text-url=https://sci-hub.do/10.1007/s00391-018-1377-9
}}
* {{medline-title
|title=What Do Clinical Supervisors Require to Teach Residents in Family Medicine How to Care for Seniors?
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29310735
|full-text-url=https://sci-hub.do/10.1017/S0714980817000460
}}
==CYP27B1==
 
* {{medline-title
|title=Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance.
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955863
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693043
}}
* {{medline-title
|title=Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism.
|date=22.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823
}}
}}
==FHL2==
==FHL2==
Строка 1393: Строка 1351:
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.09.010
}}
}}
==LRP5==
==FLT1==


* {{medline-title
* {{medline-title
|title=[[LRP5]] in age-related changes in vascular and alveolar morphogenesis in the lung.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=05.01.2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30612120
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339783
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
* {{medline-title
* {{medline-title
|title=Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|date=07.11.2018
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30404864
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aau7137
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
}}
}}
==CFD==
==FN1==


* {{medline-title
* {{medline-title
|title=Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D.
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms.
|date=07.2019
|date=22.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026383
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850482
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318
}}
}}
* {{medline-title
* {{medline-title
|title=New horizons in the compression of functional decline.
|title=Effects of Fibronectin 1 on Cell Proliferation, Senescence and Apoptosis of Human Glioma Cells Through the PI3K/AKT Signaling Pathway.
|date=01.11.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30165372
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048971
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201827
|full-text-url=https://sci-hub.do/10.1159/000492096
}}
==CHI3L1==
 
* {{medline-title
|title=Postsynaptic damage and microglial activation in AD patients could be linked CXCR4/CXCL12 expression levels.
|date=15.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32949560
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2020.147127
}}
* {{medline-title
|title=Sex difference in [[CHI3L1]] expression levels in human brain aging and in Alzheimer's disease.
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247206
|full-text-url=https://sci-hub.do/10.1016/j.brainres.2019.146305
}}
}}
==FOXA1==
==FOXA1==
Строка 1449: Строка 1393:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
}}
}}
==CCL17==
==FOXF1==


* {{medline-title
* {{medline-title
|title=Aging and chronic high-fat feeding negatively affects kidney size, function, and gene expression in CTRP1-deficient mice.
|title=Functional CRISPR screen identifies AP1-associated enhancer regulating [[FOXF1]] to modulate oncogene-induced senescence.
|date=21.10.2020
|date=17.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33085906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119690
|full-text-url=https://sci-hub.do/10.1152/ajpregu.00139.2020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097335
}}
}}
* {{medline-title
* {{medline-title
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism.
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|date=21.05.2019
|date=26.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
}}
}}
==SSB==
==FOXP3==


* {{medline-title
* {{medline-title
|title=Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study.
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|date=03.12.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816850
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950484
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
}}
}}
* {{medline-title
* {{medline-title
|title=WHIRLY1 Occupancy Affects Histone Lysine Modification and [i]WRKY53[/i] Transcription in [i]Arabidopsis[/i] Developmental Manner.
|title=Enhanced expression of PD-1 and other activation markers by CD4+ T cells of young but not old patients with metastatic melanoma.
|date=2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30405658
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546435
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951899
}}
}}
==HGD==
==FSTL3==


* {{medline-title
* {{medline-title
|title=High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans.
|title=Activin type II receptor signaling in cardiac aging and heart failure.
|date=2019
|date=06.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31846489
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124007
}}
}}
* {{medline-title
* {{medline-title
|title=A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of [i]C. elegans[/i].
|title=Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise.
|date=05.10.2018
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30085147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179167
}}
}}
==SMAD2==
==FUNDC1==


* {{medline-title
* {{medline-title
|title=Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation.
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence.
|date=02.2020
|date=15.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31674011
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833
}}
}}
* {{medline-title
* {{medline-title
|title=Restoring extracellular matrix synthesis in senescent stem cells.
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.
|date=10.2019
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287964
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766659
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068
}}
}}
==LRP4==
==GALT==


* {{medline-title
* {{medline-title
|title=Multiple MuSK signaling pathways and the aging neuromuscular junction.
|title=Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life.
|date=13.07.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32353380
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30523311
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2020.135014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375790
}}
}}
* {{medline-title
* {{medline-title
|title=Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing [[LRP4]].
|title=Dietary Animal Plasma Proteins Improve the Intestinal Immune Response in Senescent Mice.
|date=10.10.2018
|date=11.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171091
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29232896
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181315
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748796
}}
}}
==DDX58==
==GAS6==


* {{medline-title
* {{medline-title
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|date=14.01.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated mRNA expression changes in bovine endometrial cells in vitro.
|title=Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
|date=14.08.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28806906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28957414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556672
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619771
}}
}}
==HAL==
==GATA2==


* {{medline-title
* {{medline-title
|title=Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population.
|title=[[GATA2]] hypomorphism induces chronic myelomonocytic leukemia in mice.
|date=06-09.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31066639
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710465
|full-text-url=https://sci-hub.do/10.1080/15360288.2018.1513434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447832
}}
}}
* {{medline-title
* {{medline-title
|title=Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats.
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|date=06.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31049689
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|full-text-url=https://sci-hub.do/10.1007/s00540-019-02646-0
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
}}
}}
==FAAH==
==GATA3==


* {{medline-title
* {{medline-title
|title=Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice.
|title=An imbalance in the T-helper phenotypes displayed by senescent [[CD4]] [[CD28]]  T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus.
|date=02.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32095523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015690
|full-text-url=https://sci-hub.do/10.1177/0961203318793715
}}
}}
* {{medline-title
* {{medline-title
|title=Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan.
|title=Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland.
|date=05.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30911178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30004288
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548519
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262508
}}
}}
==FABP4==
==GDF3==


* {{medline-title
* {{medline-title
|title=Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation.
|title=In vivo [[GDF3]] administration abrogates aging related muscle regeneration delay following acute sterile injury.
|date=05.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003692
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.118.310797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156497
}}
}}
* {{medline-title
* {{medline-title
|title=Endothelial [[APLNR]] regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.
|date=13.09.2017
|date=05.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703224
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149
}}
}}
==TREX1==
==GIT2==


* {{medline-title
* {{medline-title
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|title=Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic [[GIT2]] in aging trajectories.
|date=2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31574270
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111150
}}
}}
* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=[[GIT2]]-A keystone in ageing and age-related disease.
|date=06.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002
}}
}}
==MAP1LC3B==
==GK==


* {{medline-title
* {{medline-title
|title=The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells.
|title=Progression of diabetic kidney disease in T2DN rats.
|date=01.09.2018
|date=01.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566426
|full-text-url=https://sci-hub.do/10.1556/2060.105.2018.3.20
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960784
}}
}}
* {{medline-title
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|title=Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging.
|date=2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30609251
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413652
}}
}}
==PYY==
==GLS==


* {{medline-title
* {{medline-title
|title=Peptide YY ([[PYY]]) Is Expressed in Human Skeletal Muscle Tissue and Expanding Human Muscle Progenitor Cells.
|title=Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography.
|date=2019
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890955
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29784576
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412030
|full-text-url=https://sci-hub.do/10.1016/j.amjcard.2018.03.355
}}
}}
* {{medline-title
* {{medline-title
|title=Peptide YY induces characteristic meal patterns of aged mice.
|title=Future Perspectives for Management of Stage A Heart Failure.
|date=11.2017
|date=01.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28916138
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731506
|full-text-url=https://sci-hub.do/10.1016/j.yhbeh.2017.09.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055033
}}
}}
==MAPK14==
==GNG3==


* {{medline-title
* {{medline-title
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|date=10.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
}}
}}
* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=15.11.2017
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==NCL==
==GNRH1==


* {{medline-title
* {{medline-title
|title=Factors Affecting Microvascular Responses in the Bulbar Conjunctiva in Habitual Contact Lens Wearers.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=01.08.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30098199
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088803
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
* {{medline-title
* {{medline-title
|title=Small nucleoli are a cellular hallmark of longevity.
|title=Elucidating the genetic architecture of reproductive ageing in the Japanese population.
|date=30.08.2017
|date=17.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28853436
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29773799
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582349
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958096
}}
}}
==ACACA==
==GPR39==


* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=Zinc-mediated Neurotransmission in Alzheimer's Disease: A Potential Role of the [[GPR39]] in Dementia.
|date=08.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31272355
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327932
}}
}}
* {{medline-title
* {{medline-title
|title=GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling.
|title=[[GPR39]] agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence.
|date=07.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29694926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237151
|full-text-url=https://sci-hub.do/10.1016/j.bone.2018.04.014
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1626405
}}
}}
==ATG3==
==GPT==


* {{medline-title
* {{medline-title
|title=Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells.
|title=Brain Structural-Behavioral Correlates Underlying Grooved Pegboard Test Performance Across Lifespan.
|date=01.04.2020
|date=07.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32244623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32631206
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235898
|full-text-url=https://sci-hub.do/10.1080/00222895.2020.1787320
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults.
|date=09.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31275139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592113
}}
}}
==AREG==
==GRIK2==


* {{medline-title
* {{medline-title
|title=Targeting amphiregulin ([[AREG]]) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
|title=Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2.
|date=12.2019
|date=11-12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31493351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099472
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826133
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675648
}}
}}
* {{medline-title
* {{medline-title
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|title=Isoforms of Ionotropic Glutamate Receptor [[GRIK2]] Induce Senescence of Carcinoma Cells.
|date=2019
|date=01-02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30587499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348395
}}
}}
==PTPN11==
==GRK5==


* {{medline-title
* {{medline-title
|title=Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array.
|title=Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone.
|date=01.10.2020
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32888012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31043680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494869
}}
}}
* {{medline-title
* {{medline-title
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|title=[[GRK5]] - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders.
|date=04.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30618771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304357
}}
}}
==NOP10==
==GRSF1==


* {{medline-title
* {{medline-title
|title=Pseudouridylation defect due to [i]DKC1[/i] and [i][[NOP10]][/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis.
|title=[[GRSF1]] is an age-related regulator of senescence.
|date=30.06.2020
|date=03.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554502
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334496
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447602
}}
}}
* {{medline-title
* {{medline-title
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|title=[[GRSF1]] suppresses cell senescence.
|date=04.2018
|date=07.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30086537
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128438
}}
}}
==MTM1==
==GSTA4==


* {{medline-title
* {{medline-title
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.
|title=Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue.
|date=20.03.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30472277
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.013
}}
}}
* {{medline-title
* {{medline-title
|title=Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=19.11.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451843
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==IDS==
==HAL==


* {{medline-title
* {{medline-title
|title=Effect of immediate dentine sealing on the aging and fracture strength of lithium disilicate inlays and overlays.
|title=Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population.
|date=10.2020
|date=06-09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32957211
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31066639
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2020.103906
|full-text-url=https://sci-hub.do/10.1080/15360288.2018.1513434
}}
}}
* {{medline-title
* {{medline-title
|title=Increased double limb support times during walking in right limb dominant healthy older adults with low bone density.
|title=Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats.
|date=06.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730490
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31049689
|full-text-url=https://sci-hub.do/10.1016/j.gaitpost.2018.04.036
|full-text-url=https://sci-hub.do/10.1007/s00540-019-02646-0
}}
}}
==SV2A==
==HAPLN1==


* {{medline-title
* {{medline-title
|title=Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging.
|title=Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility.
|date=01.10.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30014145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279173
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328333
}}
}}
* {{medline-title
* {{medline-title
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|title=Age-Related Changes in [[HAPLN1]] Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis.
|date=10.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328344
}}
}}
==NMNAT1==
==HAS1==


* {{medline-title
* {{medline-title
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=06.2019
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts.
|date=12.2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7
}}
}}
==VCAM1==
==HBP1==


* {{medline-title
* {{medline-title
|title=Sunitinib facilitates metastatic breast cancer spreading by inducing endothelial cell senescence.
|title=Suppression of p38/[[HBP1]] pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence.
|date=29.09.2020
|date=03-04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32993785
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32549582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526390
|full-text-url=https://sci-hub.do/10.23812/20-63-A-6
}}
}}
* {{medline-title
* {{medline-title
|title=Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell [[VCAM1]].
|title=Transcription factor [[HBP1]]: A regulator of senescence and apoptosis of preadipocytes.
|date=06.2019
|date=17.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31086348
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331641
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642642
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.07.048
}}
}}
==NOS2==
==HCN1==


* {{medline-title
* {{medline-title
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity.
|title=Protein expression changes of [[HCN1]] and HCN2 in hippocampal subregions of gerbils during the normal aging process.
|date=10.2019
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32128096
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038419
}}
}}
* {{medline-title
* {{medline-title
|title=Secreted α-Klotho maintains cartilage tissue homeostasis by repressing [i][[NOS2]][/i] and [i]ZIP8-MMP13[/i] catabolic axis.
|title=HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation.
|date=19.06.2018
|date=15.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29920476
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30124776
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046234
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376092
}}
}}
==SCAP==
==HGD==


* {{medline-title
* {{medline-title
|title=Dementia outcomes after addition of proxy-based assessments for deceased or proxy-dependent participants.
|title=High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans.
|date=10.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31034676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31846489
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742525
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917275
}}
}}
* {{medline-title
* {{medline-title
|title=Increased hepatic INSIG-[[SCAP]]-SREBP expression is associated with cholesterol metabolism disorder in assisted reproductive technology-conceived aged mice.
|title=A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of [i]C. elegans[/i].
|date=03.2019
|date=05.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30562550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299269
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2018.12.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224263
}}
}}
==AGER==
==HLA-A==


* {{medline-title
* {{medline-title
|title=Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model.
|title=Reduced expression of the lncRNA NRON is a potential hallmark of the CMV-amplified CD8+ T cell accumulations commonly seen in older humans.
|date=01.10.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31575929
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773724
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.004
}}
}}
* {{medline-title
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|date=03.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
}}
}}
==PDC==
==HLA-B==


* {{medline-title
* {{medline-title
|title=The mitochondrial translocase of the inner membrane PaTim54 is involved in defense response and longevity in Podospora anserina.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=11.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31351193
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://sci-hub.do/10.1016/j.fgb.2019.103257
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
* {{medline-title
* {{medline-title
|title=Neuron-specific knockdown of Drosophila [[PDHB]] induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting.
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|date=15.05.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501567
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.02.035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
}}
}}
==SLC25A24==
==HLA-C==


* {{medline-title
* {{medline-title
|title=De Novo Mutations in [[SLC25A24]] Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=02.11.2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29100094
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673633
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
* {{medline-title
* {{medline-title
|title=De Novo Mutations in [[SLC25A24]] Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction.
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|date=02.11.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29100093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
}}
}}
==DICER1==
==HLA-DPB1==


* {{medline-title
* {{medline-title
|title=[[DICER1]]: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging.
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|date=2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087677
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066587
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
}}
}}
* {{medline-title
* {{medline-title
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=06.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==LDHA==
==HMOX1==


* {{medline-title
* {{medline-title
|title=Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16  inactivation.
|title=Well-aging: A new strategy for skin homeostasis under multi-stressed conditions.
|date=26.02.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482580
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31232507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828408
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003805
}}
* {{medline-title
|title=Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476819
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.004
}}
}}
==SNCB==
* {{medline-title
* {{medline-title
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
Строка 1890: Строка 1826:
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
}}
* {{medline-title
|title=Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro.
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047277
}}
==AQP3==
* {{medline-title
|title=Transbuccal platform for delivery of lipogenic actives to facial skin: Because fat matters.
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592290
|full-text-url=https://sci-hub.do/10.1002/term.3087
}}
* {{medline-title
|title=[Age-related changes of water transport by corneal endothelial cells in rats.]
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322730
}}
}}
==HRAS==
==HRAS==
Строка 1925: Строка 1841:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032038
}}
}}
==SUV39H1==
==HSF2==


* {{medline-title
* {{medline-title
|title=Increase in hippocampal histone H3K9me3 is negatively correlated with memory in old male mice.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=04.2020
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31760560
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09850-1
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
* {{medline-title
* {{medline-title
|title=Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation
|title=Nutrition and water temperature regulate the expression of heat-shock proteins in golden pompano larvae (Trachinotus ovata, Limmaeus 1758).
|date=27.09.2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952292
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30397841
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0578-x
}}
}}
==E2F2==
==HSPA1A==


* {{medline-title
* {{medline-title
|title=MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment.
|title=Vitamin D3 treatment regulates apoptosis, antioxidant defense system, and DNA integrity in the epididymal sperm of an aged rat model.
|date=08.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896785
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566824
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052401
|full-text-url=https://sci-hub.do/10.1002/mrd.23280
}}
}}
* {{medline-title
* {{medline-title
|title=In situ regeneration of retinal pigment epithelium by gene transfer of [[E2F2]]: a potential strategy for treatment of macular degenerations.
|title=The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells.
|date=12.2017
|date=01.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29188796
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269563
|full-text-url=https://sci-hub.do/10.1038/gt.2017.89
|full-text-url=https://sci-hub.do/10.1556/2060.105.2018.3.20
}}
}}
==VCAN==
==ID1==


* {{medline-title
* {{medline-title
|title=Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis.
|title=Commentary on Some Recent Theses Relevant to Combating Aging: April 2019.
|date=07.06.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31051334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30957657
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495079
|full-text-url=https://sci-hub.do/10.1089/rej.2019.2201
}}
}}
* {{medline-title
* {{medline-title
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.
|title=ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
|date=2019
|date=12.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847931
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603998
}}
}}
==EDARADD==
==ID3==


* {{medline-title
* {{medline-title
|title=Age prediction in living: Forensic epigenetic age estimation based on blood samples.
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|date=11.2020
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32721866
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|full-text-url=https://sci-hub.do/10.1016/j.legalmed.2020.101763
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=2017
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==TAT==
==IDE==


* {{medline-title
* {{medline-title
|title=Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides.
|title=Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity.
|date=2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31024341
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32538851
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467974
|full-text-url=https://sci-hub.do/10.3233/JAD-200308
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of HIV-1 gp120 and [[TAT]]-derived microvesicles on endothelial cell function.
|title=Hyperinsulinemia is associated with increasing insulin secretion but not with decreasing insulin clearance in an age-related metabolic dysfunction mice model.
|date=01.05.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789287
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30370604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589811
|full-text-url=https://sci-hub.do/10.1002/jcp.27667
}}
}}
==TCF7L2==
==IDS==


* {{medline-title
* {{medline-title
|title=A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder.
|title=Effect of immediate dentine sealing on the aging and fracture strength of lithium disilicate inlays and overlays.
|date=03.2020
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32015540
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32957211
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065955
|full-text-url=https://sci-hub.do/10.1016/j.jmbbm.2020.103906
}}
}}
* {{medline-title
* {{medline-title
|title=Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle.
|title=Increased double limb support times during walking in right limb dominant healthy older adults with low bone density.
|date=01.03.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30824849
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397284
|full-text-url=https://sci-hub.do/10.1016/j.gaitpost.2018.04.036
}}
}}
==GRIK2==
==IGFBP1==


* {{medline-title
* {{medline-title
|title=Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2.
|title=Role of [[IGFBP1]] in the senescence of vascular endothelial cells and severity of aging‑related coronary atherosclerosis.
|date=11-12.2020
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099472
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31545483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777673
}}
}}
* {{medline-title
* {{medline-title
|title=Isoforms of Ionotropic Glutamate Receptor [[GRIK2]] Induce Senescence of Carcinoma Cells.
|title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age.
|date=01-02.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30587499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781
}}
}}
==TTN==
==IL1A==


* {{medline-title
* {{medline-title
|title=LncRNA [[TTN]]-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis.
|title=IL1B triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via CCL2.
|date=10.10.2019
|date=25.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31600142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099841
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814585
|full-text-url=https://sci-hub.do/10.1111/aji.13365
}}
}}
* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Age-associated mRNA expression changes in bovine endometrial cells in vitro.
|date=15.11.2018
|date=14.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28806906
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556672
}}
}}
==PIEZO1==
==IL7==


* {{medline-title
* {{medline-title
|title=Niche stiffness underlies the ageing of central nervous system progenitor cells.
|title=[[SCAMP4]] enhances the senescent cell secretome.
|date=09.2019
|date=01.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31413369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967290
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075036
}}
}}
* {{medline-title
* {{medline-title
|title=On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, [[PIEZO1]], and Gardos Channels.
|title=Thymic Atrophy: Experimental Studies and Therapeutic Interventions.
|date=2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29311949
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28960415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732905
|full-text-url=https://sci-hub.do/10.1111/sji.12618
}}
}}
==HAPLN1==
==INSL3==


* {{medline-title
* {{medline-title
|title=Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility.
|title=Effect of Thyroxine Replacement on Leydig Cell and Sertoli Cell Function in Men with Hypothyroidism.
|date=01.2019
|date=05-06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279173
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33083267
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328333
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539029
}}
* {{medline-title
|title=Age related and seasonal changes of plasma concentrations of insulin-like peptide 3 and testosterone from birth to early-puberty in Thoroughbred male horses.
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31029851
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2019.04.014
}}
==IQGAP1==
 
* {{medline-title
|title=[[IQGAP1]]-dysfunction leads to induction of senescence in human vascular smooth muscle cells.
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592713
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111295
}}
* {{medline-title
|title=Hyaluronan-binding protein 1 (HABP1) overexpression triggers induction of senescence in fibroblasts cells.
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32068317
|full-text-url=https://sci-hub.do/10.1002/cbin.11326
}}
==IRF4==
 
* {{medline-title
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
}}
}}
* {{medline-title
* {{medline-title
|title=Age-Related Changes in [[HAPLN1]] Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis.
|title=Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice.
|date=01.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30279172
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28905935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328344
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672072
}}
}}
==DAPK1==
==IRF7==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|date=04.07.2019
|date=14.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
}}
}}
* {{medline-title
* {{medline-title
|title=Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of [[DAPK1]] in Aging.
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|date=05.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30120735
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1312-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
}}
}}
==KIT==
==KIT==
Строка 2093: Строка 2037:
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
}}
}}
==RIG==
==L1CAM==


* {{medline-title
* {{medline-title
|title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling.
|title=Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression.
|date=2017
|date=12.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31510944
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739972
}}
}}
* {{medline-title
* {{medline-title
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes.
|title=Induction, regulation and roles of neural adhesion molecule [[L1CAM]] in cellular senescence.
|date=12.12.2017
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29615539
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892697
}}
}}
==CXCL5==
==LAMP2==


* {{medline-title
* {{medline-title
|title=Hassall's corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus.
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|date=05.03.2019
|date=07.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30534943
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|full-text-url=https://sci-hub.do/10.1093/intimm/dxy073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
}}
}}
* {{medline-title
* {{medline-title
|title=Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age.
|title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers.
|date=09.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891542
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105902
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022
}}
}}
==MEIS1==
==LAT2==


* {{medline-title
* {{medline-title
|title=Down-regulation of [[MEIS1]] promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes.
|title=Blood glucose, amino acid profiles and nutrient transporter gene expressions in the small intestine of low and normal birthweight piglets during the early suckling period.
|date=06.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30971346
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529342
|full-text-url=https://sci-hub.do/10.1016/j.tvjl.2019.02.006
}}
}}
* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=Skeletal muscle: from birth to old age, routes to mechanical and metabolic failure.
|date=11.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29099099
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://sci-hub.do/10.24875/GMM.17000008
}}
}}
==CCNG2==
==LATS2==


* {{medline-title
* {{medline-title
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|date=2018
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
 
}}
}}
* {{medline-title
* {{medline-title
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis.
|date=07.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607
}}
}}
==BGN==
==LCT==


* {{medline-title
* {{medline-title
|title=Alterations of local functional connectivity in lifespan: A resting-state fMRI study.
|title=Functional MRI of Letter Cancellation Task Performance in Older Adults.
|date=07.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32462815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31057377
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477506
}}
}}
* {{medline-title
* {{medline-title
|title=Exploring variability in basal ganglia connectivity with functional MRI in healthy aging.
|title=Milk Intake at Midlife and Cognitive Decline over 20 Years. The Atherosclerosis Risk in Communities (ARIC) Study.
|date=12.2018
|date=17.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29442271
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039795
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302142
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691750
}}
}}
==TRPM8==
==LDHA==


* {{medline-title
* {{medline-title
|title=Morphological and functional changes in [[TRPM8]]-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice.
|title=Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16  inactivation.
|date=01.08.2018
|date=26.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29664111
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482580
|full-text-url=https://sci-hub.do/10.1002/cne.24454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828408
}}
}}
* {{medline-title
* {{medline-title
|title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases.
|title=Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming.
|date=02.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29476819
|full-text-url=https://sci-hub.do/10.1111/nmo.13185
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.004
}}
}}
==HLA-A==
==LIF==


* {{medline-title
* {{medline-title
|title=Reduced expression of the lncRNA NRON is a potential hallmark of the CMV-amplified CD8+ T cell accumulations commonly seen in older humans.
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity.
|date=01.2019
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415066
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.11.004
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174
}}
}}
* {{medline-title
* {{medline-title
|title=Cytomegalovirus-Specific T Cells Restricted by [[HLA-C]]w*0702 Increase Markedly with Age and Dominate the CD8  T-Cell Repertoire in Older People.
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.
|date=2017
|date=15.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29312307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304
}}
}}
==PER1==
==LONP1==


* {{medline-title
* {{medline-title
|title=Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells.
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence.
|date=02.2020
|date=15.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31773385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05194-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833
}}
}}
* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.
|date=21.11.2018
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068
}}
}}
==RUNX1==
==LOXL2==


* {{medline-title
* {{medline-title
|title=RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing [[RUNX1]] fusion oncoproteins.
|title=Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice.
|date=03.2018
|date=27.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29052866
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31569601
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813226
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801581
}}
}}
* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening.
|date=2017
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002285
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692735
}}
}}
==CCL21==
==LRP4==


* {{medline-title
* {{medline-title
|title=[[CCL21]]/[[CCR7]] axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
|title=Multiple MuSK signaling pathways and the aging neuromuscular junction.
|date=26.03.2019
|date=13.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30914733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32353380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435673
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2020.135014
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|title=Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing [[LRP4]].
|date=01.2018
|date=10.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181315
}}
}}
==PIK3CG==
==LRP5==


* {{medline-title
* {{medline-title
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|title=[[LRP5]] in age-related changes in vascular and alveolar morphogenesis in the lung.
|date=10.06.2019
|date=05.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30612120
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339783
}}
}}
* {{medline-title
* {{medline-title
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|title=Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand.
|date=18.03.2019
|date=07.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30404864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aau7137
}}
}}
==TBK1==
==LSR==


* {{medline-title
* {{medline-title
|title=Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of [[TBK1]] to facilitate mitophagy.
|title=Age-related changes in regiospecific expression of Lipolysis Stimulated Receptor ([[LSR]]) in mice brain.
|date=01.01.2021
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33164878
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31233547
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165997
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590887
}}
}}
* {{medline-title
* {{medline-title
|title=[[TBK1]] Suppresses [[RIPK1]]-Driven Apoptosis and Inflammation during Development and in Aging.
|title=Discriminating Alzheimer's disease progression using a new hippocampal marker from T1-weighted MRI: The local surface roughness.
|date=06.09.2018
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30146158
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128749
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865478
}}
}}
==AMT==
==LTB==


* {{medline-title
* {{medline-title
|title=A multi-method comparison of autobiographical memory impairments amongst younger and older adults.
|title=Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA + DHA.
|date=12.03.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162531
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30535619
|full-text-url=https://sci-hub.do/10.1080/13607863.2020.1729338
|full-text-url=https://sci-hub.do/10.1007/s10753-018-0949-6
}}
}}
* {{medline-title
* {{medline-title
|title=Autobiographical Memory From Different Life Stages in Individuals With Obstructive Sleep Apnea.
|title=Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis.
|date=03.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28803166
|full-text-url=https://sci-hub.do/10.1017/S1355617718001091
|full-text-url=https://sci-hub.do/10.1016/j.theriogenology.2017.07.043
}}
}}
==CDK1==
==MALT1==


* {{medline-title
* {{medline-title
|title=MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging.
|title=MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity.
|date=02.2020
|date=29.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31848878
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32350248
|full-text-url=https://sci-hub.do/10.1007/s12015-019-09924-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190641
}}
}}
* {{medline-title
* {{medline-title
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|title=[[MALT1]]-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31632405
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779721
}}
}}
==FN1==
==MAP1LC3B==


* {{medline-title
* {{medline-title
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms.
|title=The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells.
|date=22.07.2019
|date=01.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269563
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318
|full-text-url=https://sci-hub.do/10.1556/2060.105.2018.3.20
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of Fibronectin 1 on Cell Proliferation, Senescence and Apoptosis of Human Glioma Cells Through the PI3K/AKT Signaling Pathway.
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://sci-hub.do/10.1159/000492096
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
}}
==HCN1==
==MAPK14==


* {{medline-title
* {{medline-title
|title=Protein expression changes of [[HCN1]] and HCN2 in hippocampal subregions of gerbils during the normal aging process.
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|date=11.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32128096
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7038419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
}}
}}
* {{medline-title
* {{medline-title
|title=HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=15.02.2019
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30124776
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==TRPC6==
==MAPK3==


* {{medline-title
* {{medline-title
|title=Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype.
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|date=11.2020
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32686475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|full-text-url=https://sci-hub.do/10.1177/1535370220943122
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
}}
}}
* {{medline-title
* {{medline-title
|title=[[TRPC6]] in simulated microgravity of intervertebral disc cells.
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|date=10.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29968164
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|full-text-url=https://sci-hub.do/10.1007/s00586-018-5688-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
}}
}}
==ALKBH8==
==MAPKAPK2==


* {{medline-title
* {{medline-title
|title=Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming .
|title=Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks.
|date=01.2020
|date=03.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31765888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31801093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980792
}}
}}
* {{medline-title
* {{medline-title
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|date=2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
 
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
}}
}}
==PF4==
==MARCO==


* {{medline-title
* {{medline-title
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|title=Age-dependent effect between [[MARCO]] and [[TLR4]] on PMMA particle phagocytosis by macrophages.
|date=07.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225947
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653467
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of collagen peptides intake on skin ageing and platelet release in chronologically aged mice revealed by cytokine array analysis.
|title=Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria.
|date=01.2018
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28922541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28947541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742730
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679440
}}
}}
==MAPK3==
==MCL1==


* {{medline-title
* {{medline-title
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|title=[[MCL1]] gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway.
|date=04.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30296359
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
|full-text-url=https://sci-hub.do/10.1002/iub.1944
}}
}}
* {{medline-title
* {{medline-title
|title=Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway.
|title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
|date=10.2018
|date=10.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741
}}
}}
==GATA3==
==MCM2==


* {{medline-title
* {{medline-title
|title=An imbalance in the T-helper phenotypes displayed by senescent [[CD4]] [[CD28]]  T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus.
|title=Trophoblast type-specific expression of senescence markers in the human placenta.
|date=11.2018
|date=15.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111238
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327484
|full-text-url=https://sci-hub.do/10.1177/0961203318793715
|full-text-url=https://sci-hub.do/10.1016/j.placenta.2019.06.377
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland.
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=12.2018
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30004288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262508
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
}}
==HLA-DPB1==
==MCM7==


* {{medline-title
* {{medline-title
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=09.2019
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|date=10.2019
|date=08.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
}}
}}
==BAK1==
==MDH1==


* {{medline-title
* {{medline-title
|title=Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon.
|title=Oxidative Damage to the TCA Cycle Enzyme [[MDH1]] Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain.
|date=23.09.2020
|date=03.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32710818
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32175745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529960
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00861
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro.
|date=09.2017
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850038
}}
}}
==BECN1==
==MEIS1==


* {{medline-title
* {{medline-title
|title=Calpain-dependent Beclin1 cleavage stimulates senescence-associated cell death in HT22 hippocampal cells under the oxidative stress conditions.
|title=Down-regulation of [[MEIS1]] promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes.
|date=14.05.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30807795
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884246
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2019.02.036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529342
}}
}}
* {{medline-title
* {{medline-title
|title=Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-[[ULK1]] signaling pathway.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=04.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810242
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==TIMP1==
==MIF==


* {{medline-title
* {{medline-title
|title=Design, cyclization, and optimization of [[MMP13]]-[[TIMP1]] interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis.
|title=Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice.
|date=01.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352228
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31381889
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.10.141
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718337
}}
}}
* {{medline-title
* {{medline-title
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|title=Macrophage migration inhibitory factor knockdown inhibit viability and induce apoptosis of PVM/Ms.
|date=2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28990052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779918
}}
}}
==APOA5==
==MLH1==


* {{medline-title
* {{medline-title
|title=Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.
|title=The somatic mutation landscape of the human body.
|date=03.2019
|date=24.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30700132
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31874648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399473
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930685
}}
}}
* {{medline-title
* {{medline-title
|title=Longitudinal interaction between [[APOA5]] -1131T>C and overweight in the acceleration of age-related increase in arterial stiffness through the regulation of circulating triglycerides.
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=02.2019
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://sci-hub.do/10.1038/s41440-018-0137-y
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
}}
==FOXF1==
==MMP3==


* {{medline-title
* {{medline-title
|title=Functional CRISPR screen identifies AP1-associated enhancer regulating [[FOXF1]] to modulate oncogene-induced senescence.
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|date=17.08.2018
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119690
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
}}
}}
* {{medline-title
* {{medline-title
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|title=Identification of a pyridine derivative inducing senescence in ovarian cancer cell lines via P21 activation.
|date=26.06.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29143360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
|full-text-url=https://sci-hub.do/10.1111/1440-1681.12891
}}
}}
==GK==
==MTM1==


* {{medline-title
* {{medline-title
|title=Progression of diabetic kidney disease in T2DN rats.
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.
|date=01.12.2019
|date=20.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960784
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866
}}
}}
* {{medline-title
* {{medline-title
|title=Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging.
|title=Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy.
|date=04.2019
|date=19.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30609251
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451843
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413652
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243013
}}
}}
==TMPRSS2==
==MTMR14==


* {{medline-title
* {{medline-title
|title=Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants.
|title=EDTP/[[MTMR14]]: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates.
|date=09.09.2020
|date=13.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32905655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31029679
|full-text-url=https://sci-hub.do/10.1002/jbt.22626
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2019.04.053
}}
}}
* {{medline-title
* {{medline-title
|title=Expression of the SARS-CoV-2 Entry Proteins, ACE2 and [[TMPRSS2]], in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age.
|title=Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster.
|date=03.06.2020
|date=16.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32379417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30528881
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241737
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.12.009
}}
}}
==SOST==
==MVD==


* {{medline-title
* {{medline-title
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women.
|title=Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density.
|date=07.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297390
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448
|full-text-url=https://sci-hub.do/10.1136/jim-2018-000804
}}
}}
* {{medline-title
* {{medline-title
|title=Bone adaptation in response to treadmill exercise in young and adult mice.
|title=Assessing Microvascular Function in Humans from a Chronic Disease Perspective.
|date=06.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29379848
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698072
}}
}}
==S1PR1==
==NAV2==


* {{medline-title
* {{medline-title
|title=Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair.
|title=Genetic associations with age of menopause in familial longevity.
|date=22.06.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544390
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
* {{medline-title
* {{medline-title
|title=Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=04.01.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302034
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754350
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==PRC1==
==NCL==


* {{medline-title
* {{medline-title
|title=Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein [[BMI1]] in breast cancer cells.
|title=Factors Affecting Microvascular Responses in the Bulbar Conjunctiva in Habitual Contact Lens Wearers.
|date=07.2018
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30098199
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986597
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088803
}}
}}
* {{medline-title
* {{medline-title
|title=Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster.
|title=Small nucleoli are a cellular hallmark of longevity.
|date=02.2018
|date=30.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28853436
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9737-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582349
}}
}}
==MTMR14==
==NDNF==


* {{medline-title
* {{medline-title
|title=EDTP/[[MTMR14]]: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates.
|title=Effect of neuron-derived neurotrophic factor on rejuvenation of human adipose-derived stem cells for cardiac repair after myocardial infarction.
|date=13.07.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31029679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287219
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2019.04.053
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714174
}}
}}
* {{medline-title
* {{medline-title
|title=Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster.
|title=Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury.
|date=16.02.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30528881
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30062183
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.12.009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059002
}}
}}
==ZSCAN10==
==NDUFB8==


* {{medline-title
* {{medline-title
|title=RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells.
|title=Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats.
|date=10.10.2017
|date=23.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020613
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29882895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639470
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032417
}}
}}
* {{medline-title
* {{medline-title
|title=[[ZSCAN10]] expression corrects the genomic instability of iPSCs from aged donors.
|title=Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions.
|date=09.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29802507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843481
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060193
}}
}}
==CXCL11==
==NECTIN2==


* {{medline-title
* {{medline-title
|title=Endothelial cells under therapy-induced senescence secrete [[CXCL11]], which increases aggressiveness of breast cancer cells.
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|date=10.10.2020
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659248
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|full-text-url=https://sci-hub.do/10.1016/j.canlet.2020.06.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
}}
}}
* {{medline-title
* {{medline-title
|title=Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity.
|title=Apolipoprotein E region molecular signatures of Alzheimer's disease.
|date=13.03.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30867067
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29797398
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417215
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052488
}}
}}
==ADAM17==
==NLRC4==


* {{medline-title
* {{medline-title
|title=ACE2/[[ADAM17]]/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19.
|title=Hyperglycemia-induced inflamm-aging accelerates gingival senescence via [[NLRC4]] phosphorylation.
|date=2020
|date=06.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33117379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31676687
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7575774
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901307
}}
}}
* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Contribution of the inflammasome to inflammaging.
|date=25.07.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30473634
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240324
}}
}}
==HMOX1==
==NMNAT1==


* {{medline-title
* {{medline-title
|title=Well-aging: A new strategy for skin homeostasis under multi-stressed conditions.
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|date=02.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31232507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003805
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=08.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==DLX5==
==NMNAT2==


* {{medline-title
* {{medline-title
|title=Inhibition of microRNA-27b-3p relieves osteoarthritis pain via regulation of KDM4B-dependent [[DLX5]].
|title=[[NMNAT2]]-mediated NAD  generation is essential for quality control of aged oocytes.
|date=09.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856377
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909324
|full-text-url=https://sci-hub.do/10.1002/biof.1670
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516161
}}
}}
* {{medline-title
* {{medline-title
|title=Detection and evaluation of DNA methylation markers found at [[SCGN]] and [[KLF14]] loci to estimate human age.
|title=Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.
|date=11.2017
|date=03.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854399
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978465
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640801
}}
}}
==MARCO==
==NNMT==


* {{medline-title
* {{medline-title
|title=Age-dependent effect between [[MARCO]] and [[TLR4]] on PMMA particle phagocytosis by macrophages.
|title=Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle.
|date=08.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225947
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469996
}}
}}
* {{medline-title
* {{medline-title
|title=Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria.
|title=Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy.
|date=01.11.2017
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28947541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30192747
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679440
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191153
}}
}}
==CDKN2B==
==NOP10==


* {{medline-title
* {{medline-title
|title=Molecular Genetics and Functional Analysis Implicate [i][[CDKN2B]]AS1-[[CDKN2B]][/i] Involvement in POAG Pathogenesis.
|title=Pseudouridylation defect due to [i]DKC1[/i] and [i][[NOP10]][/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis.
|date=21.08.2020
|date=30.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32825664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32554502
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564117
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334496
}}
}}
* {{medline-title
* {{medline-title
|title=Interference of the long noncoding RNA [[CDKN2B]]-AS1 upregulates miR-181a-5p/TGFβI axis to restrain the metastasis and promote apoptosis and senescence of cervical cancer cells.
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|date=04.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884187
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488111
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
}}
}}
==LIF==
==NOS2==


* {{medline-title
* {{medline-title
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity.
|title=Genetic background, epigenetic factors and dietary interventions which influence human longevity.
|date=25.06.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31309340
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09824-3
}}
}}
* {{medline-title
* {{medline-title
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.
|title=Secreted α-Klotho maintains cartilage tissue homeostasis by repressing [i][[NOS2]][/i] and [i]ZIP8-MMP13[/i] catabolic axis.
|date=15.03.2019
|date=19.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29920476
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046234
}}
}}
==CCN3==
==NOTCH3==


* {{medline-title
* {{medline-title
|title=[[CCN3]] Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=2020
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33304321
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7701218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
* {{medline-title
* {{medline-title
|title=[[CCN3]] (NOV) Drives Degradative Changes in Aging Articular Cartilage.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=13.10.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33066270
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593953
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==FOXP3==
==NPR1==


* {{medline-title
* {{medline-title
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|title=The [[NPR1]]-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana.
|date=2019
|date=03.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33270345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
|full-text-url=https://sci-hub.do/10.1111/jipb.13044
}}
}}
* {{medline-title
* {{medline-title
|title=Enhanced expression of PD-1 and other activation markers by CD4+ T cells of young but not old patients with metastatic melanoma.
|title=Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis.
|date=06.2018
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29546435
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32540002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951899
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2020.110472
}}
}}
==PSEN2==
==NRK==


* {{medline-title
* {{medline-title
|title=Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human [[PSEN2]].
|title=[Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/[[ULK1]] signaling activation].
|date=2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31978074
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30989992
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980398
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20181205.001
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition.
|title=Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-[[ULK1]] signaling-mediated autophagy.
|date=03.2020
|date=24.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31862541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585174
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462087
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326678
}}
}}
==C9orf72==
==NTS==


* {{medline-title
* {{medline-title
|title=Carriership of two copies of [[C9orf72]] hexanucleotide repeat intermediate-length alleles is a risk factor for ALS in the Finnish population.
|title=Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension.
|date=09.11.2020
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168078
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140326
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654028
|full-text-url=https://sci-hub.do/10.1080/07420528.2019.1613424
}}
}}
* {{medline-title
* {{medline-title
|title=[[C9]]orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons.
|title=Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats.
|date=29.08.2018
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019141
}}
}}
==DSP==
==OAT==


* {{medline-title
* {{medline-title
|title=Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions.
|title=Opioid agonist treatment reduces losses in quality of life and quality-adjusted life expectancy in heroin users: Evidence from real world data.
|date=10.2019
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754798
|full-text-url=https://sci-hub.do/10.1016/j.drugalcdep.2019.05.003
}}
}}
* {{medline-title
* {{medline-title
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease.
|title=Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats.
|date=05.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30712161
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00663-x
}}
}}
==F7==
==PAK1==


* {{medline-title
* {{medline-title
|title=The Pattern of Mu Rhythm Modulation During Emotional Destination Memory: Comparison Between Mild Cognitive Impairment Patients and Healthy Controls.
|title=1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating [[PAK1]] at nM levels.
|date=2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31524160
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29760342
|full-text-url=https://sci-hub.do/10.3233/JAD-190311
|full-text-url=https://sci-hub.do/10.5582/ddt.2018.01018
}}
}}
* {{medline-title
* {{medline-title
|title=High levels of incidental physical activity are positively associated with cognition and EEG activity in aging.
|title=From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic [[PAK1]]-blockers/longevity-promoters for cancer therapy.
|date=2018
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29370215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814374
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784952
|full-text-url=https://sci-hub.do/10.1016/j.ejmech.2017.07.043
}}
}}
==ATG12==
==PAPPA==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=09.2017
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==FANCD2==
==PDC==


* {{medline-title
* {{medline-title
|title=TFG-maintaining stability of overlooked [[FANCD2]] confers early DNA-damage response.
|title=The mitochondrial translocase of the inner membrane PaTim54 is involved in defense response and longevity in Podospora anserina.
|date=24.10.2020
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099537
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31351193
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655164
|full-text-url=https://sci-hub.do/10.1016/j.fgb.2019.103257
}}
}}
* {{medline-title
* {{medline-title
|title=[[FANCD2]] and DNA Damage.
|title=Neuron-specific knockdown of Drosophila [[PDHB]] induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting.
|date=19.08.2017
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825622
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578191
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.02.035
}}
}}
==CAST==
==PDCD4==


* {{medline-title
* {{medline-title
|title=Cytomatrix proteins [[CAST]] and ELKS regulate retinal photoreceptor development and maintenance.
|title=Petal abscission in roses is associated with the activation of a truncated version of the animal [[PDCD4]] homologue, RbPCD1.
|date=05.11.2018
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30190286
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521226
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219712
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2019.110242
}}
}}
* {{medline-title
* {{medline-title
|title=Short Telomeres Induce p53 and Autophagy and Modulate Age-Associated Changes in Cardiac Progenitor Cell Fate.
|title=[[PDCD4]] Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression.
|date=06.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29441645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30687637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334536
}}
}}
==DRD3==
==PDE4D==


* {{medline-title
* {{medline-title
|title=Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality.
|title=Phosphodiesterase [[PDE4D]] Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau.
|date=02.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30439596
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33192469
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.10.012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655962
}}
}}
* {{medline-title
* {{medline-title
|title=Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.
|title=Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function.
|date=07.2018
|date=02.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29637543
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30409425
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105503
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.180
}}
}}
==ID3==
==PER1==


* {{medline-title
* {{medline-title
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|title=Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells.
|date=08.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31773385
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05194-8
}}
}}
* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=02.2018
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
==CHM==
==PF4==


* {{medline-title
* {{medline-title
|title=[Molecular regulative mechanisms of aging and interventional effects of Chinese herbal medicine].
|title=TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity.
|date=08.2017
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171222
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485681
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20170731.001
|full-text-url=https://sci-hub.do/10.1002/prca.201800024
}}
}}
* {{medline-title
* {{medline-title
|title=[Molecular mechanisms of autophagy in regulating renal aging and interventional effects of Chinese herbal medicine].
|title=Effects of collagen peptides intake on skin ageing and platelet release in chronologically aged mice revealed by cytokine array analysis.
|date=11.2016
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28929674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28922541
|full-text-url=https://sci-hub.do/10.4268/cjcmm20162105
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742730
}}
}}
==GPR39==
==PGD==


* {{medline-title
* {{medline-title
|title=Zinc-mediated Neurotransmission in Alzheimer's Disease: A Potential Role of the [[GPR39]] in Dementia.
|title=Primary Care for the Elderly Bereaved: Recommendations for Medical Education.
|date=2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31272355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29500657
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327932
|full-text-url=https://sci-hub.do/10.1007/s10880-018-9556-9
}}
}}
* {{medline-title
* {{medline-title
|title=[[GPR39]] agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence.
|title=High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles.
|date=12.2019
|date=01.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31237151
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29303233
|full-text-url=https://sci-hub.do/10.1080/21691401.2019.1626405
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844656
}}
}}
==B2M==
==PGP==


* {{medline-title
* {{medline-title
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes.
|title=Age-associated changes of the intrinsic nervous system in relation with interstitial cells in the pre-weaning goat rumen.
|date=03.2019
|date=14.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31305258
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660047
}}
}}
* {{medline-title
* {{medline-title
|title=Association between serum β2-microglobulin levels and frailty in an elderly Chinese population: results from RuLAS.
|title=Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats.
|date=2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081654
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652941
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705109
}}
}}
==HBP1==
==PIEZO1==


* {{medline-title
* {{medline-title
|title=Suppression of p38/[[HBP1]] pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence.
|title=Niche stiffness underlies the ageing of central nervous system progenitor cells.
|date=03-04.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32549582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31413369
|full-text-url=https://sci-hub.do/10.23812/20-63-A-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025879
}}
}}
* {{medline-title
* {{medline-title
|title=Transcription factor [[HBP1]]: A regulator of senescence and apoptosis of preadipocytes.
|title=On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, [[PIEZO1]], and Gardos Channels.
|date=17.09.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331641
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29311949
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.07.048
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732905
}}
}}
==DEGS1==
==PIK3CG==


* {{medline-title
* {{medline-title
|title=[Frailty: Prevalence in the Resident Population of Germany 70 - 79 Years of Age - a Population-Based Approach].
|title=Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/[[SIRT1]] pathway.
|date=11.2017
|date=10.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29156480
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182679
|full-text-url=https://sci-hub.do/10.1055/s-0043-105841
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594820
}}
}}
* {{medline-title
* {{medline-title
|title=Physical exercise and cognitive function across the life span: Results of a nationwide population-based study.
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|date=05.2018
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28919495
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|full-text-url=https://sci-hub.do/10.1016/j.jsams.2017.08.022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
}}
}}
==ACOX1==
==PLD2==


* {{medline-title
* {{medline-title
|title=Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes.
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|date=04.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677513
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|full-text-url=https://sci-hub.do/10.1016/j.cbpb.2019.01.005
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
}}
}}
* {{medline-title
* {{medline-title
|title=Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging.
|title=Role of phospholipase D in the lifespan of Caenorhabditis elegans.
|date=2018
|date=06.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29765501
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29622768
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889864
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938010
}}
}}
==TXNRD2==
==PLIN2==


* {{medline-title
* {{medline-title
|title=Wogonin induces cellular senescence in breast cancer via suppressing [[TXNRD2]] expression.
|title=Cardiac overexpression of perilipin 2 induces atrial steatosis, connexin 43 remodeling, and atrial fibrillation in aged mice.
|date=10.2020
|date=01.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32671444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31661297
|full-text-url=https://sci-hub.do/10.1007/s00204-020-02842-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957375
}}
}}
* {{medline-title
* {{medline-title
|title=Loss of [[IDH2]] Accelerates Age-related Hearing Loss in Male Mice.
|title=[[HDAC6]] Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of [[PLIN2]] in Drosophila.
|date=22.03.2018
|date=09.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567975
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28966044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864918
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2017.09.001
}}
}}
==SAA1==
==PLK4==


* {{medline-title
* {{medline-title
|title=Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells.
|title=A novel lncRNA [[PLK4]] up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence.
|date=2018
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32243714
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205816
}}
}}
* {{medline-title
* {{medline-title
|title=Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients.
|title=Differential expression of AURKA/[[PLK4]] in quiescence and senescence of osteosarcoma U2OS cells.
|date=2017
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846716
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32200684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573208
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217361
}}
}}
==STIM1==
==POSTN==


* {{medline-title
* {{medline-title
|title=Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis.
|title=A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals [[POSTN]] As a New Element in Proline Metabolic Disorder.
|date=02.2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31833196
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996945
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284769
}}
}}
* {{medline-title
* {{medline-title
|title=Ca  entry via [[TRPC1]] is essential for cellular differentiation and modulates secretion via the SNARE complex.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=01.07.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182642
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==LAMP2==
==POT1==


* {{medline-title
* {{medline-title
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|title=MiR-185 targets [[POT1]] to induce telomere dysfunction and cellular senescence.
|date=07.12.2018
|date=18.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32687062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425516
}}
}}
* {{medline-title
* {{medline-title
|title=Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers.
|title=Seryl tRNA synthetase cooperates with [[POT1]] to regulate telomere length and cellular senescence.
|date=02.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203401
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31815007
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.11.022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882858
}}
}}
==CPE==
==PPID==


* {{medline-title
* {{medline-title
|title=Cross-Sectional and Cumulative Longitudinal Central Nervous System Penetration Effectiveness Scores Are Not Associated With Neurocognitive Impairment in a Well Treated Aging Human Immunodeficiency Virus-Positive Population in Switzerland.
|title=Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population.
|date=07.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32058159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612860
|full-text-url=https://sci-hub.do/10.1016/j.vetimm.2020.110013
}}
}}
* {{medline-title
* {{medline-title
|title=COCOA (Theobroma cacao) Polyphenol-Rich Extract Increases the Chronological Lifespan of Saccharomyces cerevisiae.
|title=Epidemiology of pituitary pars intermedia dysfunction: A systematic literature review of clinical presentation, disease prevalence and risk factors.
|date=2016
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29240368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29704935
 
|full-text-url=https://sci-hub.do/10.1016/j.tvjl.2018.03.002
}}
}}
==STAT5A==
==PPM1D==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Detectible mosaic truncating [[PPM1D]] mutations, age and breast cancer risk.
|date=15.11.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30850729
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1038/s10038-019-0589-1
}}
}}
* {{medline-title
* {{medline-title
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|title=Age-related remodelling of oesophageal epithelia by mutated cancer drivers.
|date=28.10.2017
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30602793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0811-x
}}
}}
==NTS==
==PRC1==


* {{medline-title
* {{medline-title
|title=Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension.
|title=Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein [[BMI1]] in breast cancer cells.
|date=08.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140326
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29528145
|full-text-url=https://sci-hub.do/10.1080/07420528.2019.1613424
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986597
}}
}}
* {{medline-title
* {{medline-title
|title=Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats.
|title=Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster.
|date=01.08.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29518407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29177687
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019141
|full-text-url=https://sci-hub.do/10.1007/s10522-017-9737-1
}}
}}
==PGP==
==PROC==


* {{medline-title
* {{medline-title
|title=Age-associated changes of the intrinsic nervous system in relation with interstitial cells in the pre-weaning goat rumen.
|title=Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation.
|date=14.07.2019
|date=15.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31305258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31633180
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660047
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157190
}}
}}
* {{medline-title
* {{medline-title
|title=Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats.
|title=Effects of feeding frequency of an elevated plane of milk replacer and calf age on behavior, and glucose and insulin kinetics in male Holstein calves.
|date=2017
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29182640
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30419975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705109
|full-text-url=https://sci-hub.do/10.1017/S175173111800294X
}}
}}
==GDF3==
==PSEN2==


* {{medline-title
* {{medline-title
|title=In vivo [[GDF3]] administration abrogates aging related muscle regeneration delay following acute sterile injury.
|title=Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human [[PSEN2]].
|date=10.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003692
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31978074
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156497
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980398
}}
}}
* {{medline-title
* {{medline-title
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.
|title=Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition.
|date=05.10.2017
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31862541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462087
}}
}}
==TNNT3==
==PTBP1==


* {{medline-title
* {{medline-title
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence.
|date=06.02.2019
|date=11.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934
}}
}}
* {{medline-title
* {{medline-title
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.
|title=[[PTBP1]]-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.
|date=15.07.2018
|date=09.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990503
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048363
}}
}}
==GPT==
==PTPN11==


* {{medline-title
* {{medline-title
|title=Brain Structural-Behavioral Correlates Underlying Grooved Pegboard Test Performance Across Lifespan.
|title=Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array.
|date=07.07.2020
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32631206
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32888012
|full-text-url=https://sci-hub.do/10.1080/00222895.2020.1787320
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568434
}}
}}
* {{medline-title
* {{medline-title
|title=Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults.
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|date=2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31275139
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
}}
}}
==ANGPTL2==
==PTS==


* {{medline-title
* {{medline-title
|title=Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study.
|title=Posttraumatic stress symptom persistence across 24 years: association with brain structures.
|date=01.05.2020
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31840173
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30830577
|full-text-url=https://sci-hub.do/10.1093/ndt/gfz236
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722032
}}
}}
* {{medline-title
* {{medline-title
|title=Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice.
|title=Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis.
|date=02.02.2018
|date=18.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29191837
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052528
}}
}}
==IL1A==
==PTX3==


* {{medline-title
* {{medline-title
|title=IL1B triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via CCL2.
|title=Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects.
|date=25.10.2020
|date=27.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33099841
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012711
|full-text-url=https://sci-hub.do/10.1111/aji.13365
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070734
}}
}}
* {{medline-title
* {{medline-title
|title=Age-associated mRNA expression changes in bovine endometrial cells in vitro.
|title=Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study.
|date=14.08.2017
|date=13.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28806906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31808814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556672
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357589
}}
}}
==PUM2==
==PUM2==
Строка 3101: Строка 3045:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396316
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396316
}}
}}
==BTK==
==PYY==


* {{medline-title
* {{medline-title
|title=Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition.
|title=Peptide YY ([[PYY]]) Is Expressed in Human Skeletal Muscle Tissue and Expanding Human Muscle Progenitor Cells.
|date=01.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31736210
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412030
}}
}}
* {{medline-title
* {{medline-title
|title=[[BTK]] suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling.
|title=Peptide YY induces characteristic meal patterns of aged mice.
|date=22.08.2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28915637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28916138
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593608
|full-text-url=https://sci-hub.do/10.1016/j.yhbeh.2017.09.003
}}
}}
==MALT1==
==RAD52==


* {{medline-title
* {{medline-title
|title=MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity.
|title=Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae.
|date=29.04.2020
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32350248
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075257
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190641
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563841
}}
}}
* {{medline-title
* {{medline-title
|title=[[MALT1]]-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging.
|title=Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human [[RAD52]] gene in a cardiovascular cohort.
|date=2019
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31632405
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779721
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.10.003
}}
}}
==DAO==
==RAG1==


* {{medline-title
* {{medline-title
|title=Age- and gender-dependent D-amino acid oxidase activity in mouse brain and peripheral tissues: implication for aging and neurodegeneration.
|title=T cell senescence accelerates Angiotensin II-induced target organ damage.
|date=01.08.2019
|date=12.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30938755
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32049355
|full-text-url=https://sci-hub.do/10.1093/jb/mvz025
|full-text-url=https://sci-hub.do/10.1093/cvr/cvaa032
}}
}}
* {{medline-title
* {{medline-title
|title=Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging.
|title=Aged murine hematopoietic stem cells drive aging-associated immune remodeling.
|date=01.11.2017
|date=09.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29093468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29891535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665939
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137572
}}
}}
==FSTL3==
==RAN==


* {{medline-title
* {{medline-title
|title=Activin type II receptor signaling in cardiac aging and heart failure.
|title=Rapid automatized naming ([[RAN]]): effects of aging on a predictor of reading skill.
|date=06.03.2019
|date=17.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842316
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32799742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124007
|full-text-url=https://sci-hub.do/10.1080/13825585.2020.1806987
}}
}}
* {{medline-title
* {{medline-title
|title=Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise.
|title=SCA8 [[RAN]] polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F.
|date=01.10.2018
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30085147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30206144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179167
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166133
}}
}}
==BMP15==
==RGN==


* {{medline-title
* {{medline-title
|title=Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro.
|title=Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04.
|date=01.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30358012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29675370
|full-text-url=https://sci-hub.do/10.1002/mrd.23079
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902356
}}
}}
* {{medline-title
* {{medline-title
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|title=Effect of supplementation of recombinant Regucalcin in extender on cryopreservation of spermatozoa of water buffalo (Bubalus bubalis).
|date=18.10.2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782859
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
|full-text-url=https://sci-hub.do/10.1002/mrd.22873
}}
}}
==GIT2==
==RIG==


* {{medline-title
* {{medline-title
|title=Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic [[GIT2]] in aging trajectories.
|title=Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of [[RIG]]-I/NF-κB Signaling.
|date=12.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31574270
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403373
|full-text-url=https://sci-hub.do/10.1016/j.mad.2019.111150
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778393
}}
}}
* {{medline-title
* {{medline-title
|title=[[GIT2]]-A keystone in ageing and age-related disease.
|title=Aging impairs both primary and secondary [[RIG]]-I signaling for interferon induction in human monocytes.
|date=05.2018
|date=12.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29233916
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429941
}}
}}
==PTS==
==RNF8==


* {{medline-title
* {{medline-title
|title=Posttraumatic stress symptom persistence across 24 years: association with brain structures.
|title=Expression of [[RNF8]] on cochlear apoptosis and aging in mice of different ages.
|date=08.2020
|date=03-Apr,.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30830577
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722032
 
}}
}}
* {{medline-title
* {{medline-title
|title=Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis.
|title=Function of RAD6B and [[RNF8]] in spermatogenesis.
|date=18.07.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825854
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884393
}}
}}
==FUNDC1==
==RPS6==


* {{medline-title
* {{medline-title
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence.
|title=Regulation of Amino Acid Transporters and Sensors in Response to a High protein Diet: A Randomized Controlled Trial in Elderly Men.
|date=15.03.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30932134
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833
|full-text-url=https://sci-hub.do/10.1007/s12603-019-1171-4
}}
}}
* {{medline-title
* {{medline-title
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.
|title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107.
|date=01.02.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016
}}
}}
==GNG3==
==RTEL1==


* {{medline-title
* {{medline-title
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|title=Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants.
|date=2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31444995
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826144
}}
}}
* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Genome-wide association study of telomere length among South Asians identifies a second [[RTEL1]] association signal.
|date=07.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29151059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749304
}}
}}
==CRABP2==
==RUNX1==


* {{medline-title
* {{medline-title
|title=Preconception resveratrol intake against infertility: Friend or foe?
|title=RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing [[RUNX1]] fusion oncoproteins.
|date=04.2020
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32273814
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29052866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138940
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813226
}}
}}
* {{medline-title
* {{medline-title
|title=Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females.
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|date=31.10.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089527
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663855
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
}}
}}
==GRSF1==
==S100A4==


* {{medline-title
* {{medline-title
|title=[[GRSF1]] is an age-related regulator of senescence.
|title=Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice.
|date=03.04.2019
|date=15.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944385
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447602
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894395
}}
}}
* {{medline-title
* {{medline-title
|title=[[GRSF1]] suppresses cell senescence.
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|date=07.08.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30086537
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128438
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
}}
}}
==BIN1==
==S1PR1==


* {{medline-title
* {{medline-title
|title=Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.
|title=Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair.
|date=20.03.2019
|date=22.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30894500
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544390
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aav1866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607448
}}
}}
* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota.
|date=28.03.2018
|date=04.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302034
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754350
}}
}}
==IL7==
==SAA1==


* {{medline-title
* {{medline-title
|title=[[SCAMP4]] enhances the senescent cell secretome.
|title=Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells.
|date=01.07.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967290
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884545
}}
}}
* {{medline-title
* {{medline-title
|title=Thymic Atrophy: Experimental Studies and Therapeutic Interventions.
|title=Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients.
|date=01.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28960415
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846716
|full-text-url=https://sci-hub.do/10.1111/sji.12618
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573208
}}
}}
==LOXL2==
==SCAP==


* {{medline-title
* {{medline-title
|title=Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice.
|title=Dementia outcomes after addition of proxy-based assessments for deceased or proxy-dependent participants.
|date=27.09.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31569601
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31034676
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801581
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742525
}}
}}
* {{medline-title
* {{medline-title
|title=Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening.
|title=Increased hepatic INSIG-[[SCAP]]-SREBP expression is associated with cholesterol metabolism disorder in assisted reproductive technology-conceived aged mice.
|date=01.07.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31002285
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30562550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692735
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2018.12.003
}}
}}
==WIPI2==
==SESN2==


* {{medline-title
* {{medline-title
|title=Neuronal autophagy declines substantially with age and is rescued by overexpression of [[WIPI2]].
|title=Copy Number Alterations in Papillary Thyroid Carcinomas: Does Loss of [i][[SESN2]][/i] Have a Role in Age-related Different Prognoses?
|date=02.2020
|date=09-10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32859642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984449
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472442
}}
}}
* {{medline-title
* {{medline-title
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|title=Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea.
|date=04.2019
|date=11.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28818524
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605466
}}
}}
==TBC1D5==
==SLC25A24==


* {{medline-title
* {{medline-title
|title=[[TBC1D5]]-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry.
|title=De Novo Mutations in [[SLC25A24]] Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.
|date=09.06.2020
|date=02.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32521275
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29100094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339955
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673633
}}
}}
* {{medline-title
* {{medline-title
|title=Retromer and [[TBC1D5]] maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling.
|title=De Novo Mutations in [[SLC25A24]] Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction.
|date=02.09.2019
|date=02.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31431476
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29100093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673623
}}
}}
==PLK4==
==SMAD2==


* {{medline-title
* {{medline-title
|title=A novel lncRNA [[PLK4]] up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence.
|title=Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation.
|date=05.2020
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32243714
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31674011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205816
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071816
}}
}}
* {{medline-title
* {{medline-title
|title=Differential expression of AURKA/[[PLK4]] in quiescence and senescence of osteosarcoma U2OS cells.
|title=Restoring extracellular matrix synthesis in senescent stem cells.
|date=04.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32200684
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31287964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217361
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766659
}}
}}
==LCT==
==SMAD4==


* {{medline-title
* {{medline-title
|title=Functional MRI of Letter Cancellation Task Performance in Older Adults.
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient.
|date=2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31057377
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477506
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7
}}
}}
* {{medline-title
* {{medline-title
|title=Milk Intake at Midlife and Cognitive Decline over 20 Years. The Atherosclerosis Risk in Communities (ARIC) Study.
|title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16  and Wild-Type p53.
|date=17.10.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039795
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985
}}
}}
==XRCC1==
==SNCB==


* {{medline-title
* {{medline-title
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats].
|title=Age-related distribution and potential role of [[SNCB]] in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula.
|date=07.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31128101
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180408.005
|full-text-url=https://sci-hub.do/10.1016/j.exer.2019.05.016
}}
}}
* {{medline-title
* {{medline-title
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.
|title=Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro.
|date=2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047277
}}
}}
==GAS6==
==SOCS1==


* {{medline-title
* {{medline-title
|title=Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
|title=Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus.
|date=2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31285764
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30656452
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599663
|full-text-url=https://sci-hub.do/10.1007/s10695-018-0607-9
}}
}}
* {{medline-title
* {{medline-title
|title=Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|date=2017
|date=28.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28957414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
}}
}}
==SPR==
==SORL1==


* {{medline-title
* {{medline-title
|title=Regulation of lifespan by neural excitation and REST.
|title=A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.
|date=10.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31619788
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30706571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608707
}}
}}
* {{medline-title
* {{medline-title
|title=How many geriatricians should, at minimum, be staffing health regions in Australia?
|title=Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age.
|date=03.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171127
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29865048
|full-text-url=https://sci-hub.do/10.1111/ajag.12467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263481
}}
}}
==RTEL1==
==SOST==


* {{medline-title
* {{medline-title
|title=Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants.
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women.
|date=12.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31444995
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448
}}
}}
* {{medline-title
* {{medline-title
|title=Genome-wide association study of telomere length among South Asians identifies a second [[RTEL1]] association signal.
|title=Bone adaptation in response to treadmill exercise in young and adult mice.
|date=01.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29151059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29379848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787623
}}
}}
==CBL==
==SPARCL1==


* {{medline-title
* {{medline-title
|title=Effects of cerebrolysin on nerve growth factor system in the aging rat brain.
|title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment.
|date=2017
|date=18.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29172008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701766
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664
}}
}}
* {{medline-title
* {{medline-title
|title=Skeletal Muscle CAP Expression Increases after Dietary Restriction and Aerobic Training in Women with a History of Gestational Diabetes.
|title=[[SPARCL1]] Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging.
|date=2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28989819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154276
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628746
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934753
}}
}}
==CCR6==
==SPR==


* {{medline-title
* {{medline-title
|title=Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells.
|title=Regulation of lifespan by neural excitation and REST.
|date=07.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30696983
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31619788
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599474
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893853
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|title=How many geriatricians should, at minimum, be staffing health regions in Australia?
|date=19.01.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171127
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
|full-text-url=https://sci-hub.do/10.1111/ajag.12467
}}
}}
==LONP1==
==SRR==


* {{medline-title
* {{medline-title
|title=Mitochondria organize the cellular proteostatic response and promote cellular senescence.
|title=Mediterranean diet and its components in relation to all-cause mortality: meta-analysis.
|date=15.03.2019
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31225505
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30401007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551833
|full-text-url=https://sci-hub.do/10.1017/S0007114518002593
}}
}}
* {{medline-title
* {{medline-title
|title=A mitochondrial [[FUNDC1]]/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity.
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=01.02.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30591555
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356068
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
}}
==TRPM7==
==SSB==


* {{medline-title
* {{medline-title
|title=mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development.
|title=Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study.
|date=10.2018
|date=03.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29842890
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31816850
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.05.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950484
}}
}}
* {{medline-title
* {{medline-title
|title=Role of kinase-coupled TRP channels in mineral homeostasis.
|title=WHIRLY1 Occupancy Affects Histone Lysine Modification and [i]WRKY53[/i] Transcription in [i]Arabidopsis[/i] Developmental Manner.
|date=04.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30405658
|full-text-url=https://sci-hub.do/10.1016/j.pharmthera.2017.11.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202938
}}
}}
==PDCD4==
==STAT5A==


* {{medline-title
* {{medline-title
|title=Petal abscission in roses is associated with the activation of a truncated version of the animal [[PDCD4]] homologue, RbPCD1.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=11.2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521226
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.plantsci.2019.110242
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
* {{medline-title
* {{medline-title
|title=[[PDCD4]] Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression.
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|date=2018
|date=28.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30687637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334536
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
}}
}}
==TLR7==
==STIM1==


* {{medline-title
* {{medline-title
|title=Bovine Lactoferrin Enhances [[TLR7]]-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D.
|title=Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis.
|date=2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515164
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31833196
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255898
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996945
}}
}}
* {{medline-title
* {{medline-title
|title=B cell responses to apoptotic cells in MFG-E8-/- mice.
|title=Ca  entry via [[TRPC1]] is essential for cellular differentiation and modulates secretion via the SNARE complex.
|date=2018
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30286201
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171925
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397
}}
}}
==PGD==
==SUV39H1==


* {{medline-title
* {{medline-title
|title=Primary Care for the Elderly Bereaved: Recommendations for Medical Education.
|title=Increase in hippocampal histone H3K9me3 is negatively correlated with memory in old male mice.
|date=12.2018
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29500657
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31760560
|full-text-url=https://sci-hub.do/10.1007/s10880-018-9556-9
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09850-1
}}
}}
* {{medline-title
* {{medline-title
|title=High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles.
|title=Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation
|date=01.03.2018
|date=27.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29303233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28952292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844656
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720660
}}
}}
==PTX3==
==SV2A==


* {{medline-title
* {{medline-title
|title=Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects.
|title=Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging.
|date=27.01.2020
|date=01.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32012711
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30014145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070734
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233853
}}
}}
* {{medline-title
* {{medline-title
|title=Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study.
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|date=13.07.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31808814
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
}}
}}
==TAS2R38==
==TAS2R16==
 
* {{medline-title
|title=Taste receptor polymorphisms and longevity: a systematic review and meta-analysis.
|date=10.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33170488
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01745-3
}}
* {{medline-title
|title=Taste receptors, innate immunity and longevity: the case of [[TAS2R16]] gene.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30833980
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387736
}}
==TAS2R38==


* {{medline-title
* {{medline-title
Строка 3535: Строка 3493:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
}}
}}
==ETS1==
==TAT==


* {{medline-title
* {{medline-title
|title=The transcription factor [[ETS1]] promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1.
|title=Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides.
|date=06.12.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31659122
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31024341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901313
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467974
}}
}}
* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Effects of HIV-1 gp120 and [[TAT]]-derived microvesicles on endothelial cell function.
|date=15.11.2017
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589811
}}
}}
==SMAD4==
==TBC1D5==


* {{medline-title
* {{medline-title
|title=A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient.
|title=[[TBC1D5]]-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry.
|date=09.2019
|date=09.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30843125
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32521275
|full-text-url=https://sci-hub.do/10.1007/s00595-019-01789-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339955
}}
}}
* {{medline-title
* {{medline-title
|title=E47 Governs the [[MYC]]-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16  and Wild-Type p53.
|title=Retromer and [[TBC1D5]] maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling.
|date=2018
|date=02.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003124
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31431476
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039985
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719456
}}
}}
==DDB1==
==TBK1==


* {{medline-title
* {{medline-title
|title=DCAF1 regulates Treg senescence via the ROS axis during immunological aging.
|title=Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of [[TBK1]] to facilitate mitophagy.
|date=02.11.2020
|date=01.01.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32730228
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33164878
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598062
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2020.165997
}}
}}
* {{medline-title
* {{medline-title
|title=Deletion of [[DDB1]]- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice.
|title=[[TBK1]] Suppresses [[RIPK1]]-Driven Apoptosis and Inflammation during Development and in Aging.
|date=15.06.2018
|date=06.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907856
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30146158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003934
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128749
}}
}}
==DKC1==
==TCF7L2==


* {{medline-title
* {{medline-title
|title=Successful liver transplantation in short telomere syndromes without bone marrow failure due to [[DKC1]] mutation.
|title=A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder.
|date=05.2020
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32166868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32015540
|full-text-url=https://sci-hub.do/10.1111/petr.13695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065955
}}
}}
* {{medline-title
* {{medline-title
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|title=Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle.
|date=04.2018
|date=01.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30824849
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397284
}}
}}
==DST==
==TIMELESS==


* {{medline-title
* {{medline-title
|title=Ancestral germen/soma distinction in microbes: Expanding the disposable soma theory of aging to all unicellular lineages.
|title=Loss of circadian protein [[TIMELESS]] accelerates the progression of cellular senescence.
|date=07.2020
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268207
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30100061
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101064
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.08.040
}}
}}
* {{medline-title
* {{medline-title
|title=Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study.
|title=Clock gene expression and locomotor activity predict death in the last days of life in Drosophila melanogaster.
|date=10.2019
|date=09.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386173
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30093652
|full-text-url=https://sci-hub.do/10.1111/jgs.16089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085321
}}
}}
==S100A4==
==TIMP1==


* {{medline-title
* {{medline-title
|title=Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice.
|title=Design, cyclization, and optimization of [[MMP13]]-[[TIMP1]] interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis.
|date=15.12.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31678243
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352228
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894395
|full-text-url=https://sci-hub.do/10.1016/j.ijbiomac.2018.10.141
}}
}}
* {{medline-title
* {{medline-title
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
}}
}}
==DDX41==
==TLR7==


* {{medline-title
* {{medline-title
|title=Salidroside influences the cellular cross-talk of human fetal lung diploid fibroblasts: A proteomic approach.
|title=Bovine Lactoferrin Enhances [[TLR7]]-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D.
|date=03.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29329019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30515164
|full-text-url=https://sci-hub.do/10.1016/j.etap.2018.01.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255898
}}
}}
* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=B cell responses to apoptotic cells in MFG-E8-/- mice.
|date=2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30286201
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171925
}}
}}
==MVD==
==TMPRSS2==


* {{medline-title
* {{medline-title
|title=Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density.
|title=Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants.
|date=12.2018
|date=09.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297390
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32905655
|full-text-url=https://sci-hub.do/10.1136/jim-2018-000804
|full-text-url=https://sci-hub.do/10.1002/jbt.22626
}}
}}
* {{medline-title
* {{medline-title
|title=Assessing Microvascular Function in Humans from a Chronic Disease Perspective.
|title=Expression of the SARS-CoV-2 Entry Proteins, ACE2 and [[TMPRSS2]], in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age.
|date=12.2017
|date=03.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904002
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32379417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241737
}}
}}
==GALT==
==TNNT3==


* {{medline-title
* {{medline-title
|title=Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life.
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|date=03.2019
|date=06.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30523311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375790
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
}}
}}
* {{medline-title
* {{medline-title
|title=Dietary Animal Plasma Proteins Improve the Intestinal Immune Response in Senescent Mice.
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.
|date=11.12.2017
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29232896
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748796
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179
}}
}}
==GATA2==
==TPO==


* {{medline-title
* {{medline-title
|title=[[GATA2]] hypomorphism induces chronic myelomonocytic leukemia in mice.
|title=Megakaryocytes promote osteoclastogenesis in aging.
|date=04.2019
|date=07.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32634116
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425434
}}
}}
* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex-independent) NOD.H2  mice.
|date=2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566234
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422661
}}
}}
==ACTA1==
==TREX1==


* {{medline-title
* {{medline-title
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle.
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|date=15.05.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
}}
}}
* {{medline-title
* {{medline-title
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=15.12.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==CYP3A4==
==TRH==


* {{medline-title
* {{medline-title
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|title=Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats.
|date=05.2019
|date=15.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29305326
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
|full-text-url=https://sci-hub.do/10.1016/j.toxlet.2017.12.029
}}
}}
* {{medline-title
* {{medline-title
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia.
|title=Effect of dietary carbohydrates and time of year on ACTH and cortisol concentrations in adult and aged horses.
|date=12.2017
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29195115
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442
|full-text-url=https://sci-hub.do/10.1016/j.domaniend.2017.10.005
}}
}}
==ACTB==
==TRPC6==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype.
|date=2019
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32686475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://sci-hub.do/10.1177/1535370220943122
}}
}}
* {{medline-title
* {{medline-title
|title=WNT-activated bone grafts repair osteonecrotic lesions in aged animals.
|title=[[TRPC6]] in simulated microgravity of intervertebral disc cells.
|date=27.10.2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29079746
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29968164
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660190
|full-text-url=https://sci-hub.do/10.1007/s00586-018-5688-8
}}
}}
==AGT==
==TRPM7==


* {{medline-title
* {{medline-title
|title=SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence.
|title=mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development.
|date=06.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31441382
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29842890
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469683
|full-text-url=https://sci-hub.do/10.1016/j.ijdevneu.2018.05.008
}}
}}
* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Role of kinase-coupled TRP channels in mineral homeostasis.
|date=11.2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129644
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://sci-hub.do/10.1016/j.pharmthera.2017.11.003
}}
}}
==ZEB2==
==TRPM8==


* {{medline-title
* {{medline-title
|title=miR-200b regulates cellular senescence and inflammatory responses by targeting [[ZEB2]] in pulmonary emphysema.
|title=Morphological and functional changes in [[TRPM8]]-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice.
|date=12.2020
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32070140
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29664111
|full-text-url=https://sci-hub.do/10.1080/21691401.2020.1725029
|full-text-url=https://sci-hub.do/10.1002/cne.24454
}}
}}
* {{medline-title
* {{medline-title
|title=MicroRNA-145 induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by [[ZEB2]].
|title=A comparative study on the therapeutic effect of [[TRPV1]], [[TRPA1]], and [[TRPM8]] agonists on swallowing dysfunction associated with aging and neurological diseases.
|date=05.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30479019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28799699
|full-text-url=https://sci-hub.do/10.1002/jcp.27521
|full-text-url=https://sci-hub.do/10.1111/nmo.13185
}}
}}
==PDE4D==
==TTN==


* {{medline-title
* {{medline-title
|title=Phosphodiesterase [[PDE4D]] Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau.
|title=LncRNA [[TTN]]-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis.
|date=2020
|date=10.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33192469
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31600142
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655962
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814585
}}
}}
* {{medline-title
* {{medline-title
|title=Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=02.12.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30409425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.180
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==RAD52==
==TXNRD2==


* {{medline-title
* {{medline-title
|title=Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae.
|title=Wogonin induces cellular senescence in breast cancer via suppressing [[TXNRD2]] expression.
|date=01.08.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31075257
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32671444
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563841
|full-text-url=https://sci-hub.do/10.1007/s00204-020-02842-y
}}
}}
* {{medline-title
* {{medline-title
|title=Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human [[RAD52]] gene in a cardiovascular cohort.
|title=Loss of [[IDH2]] Accelerates Age-related Hearing Loss in Male Mice.
|date=10.2017
|date=22.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024686
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29567975
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.10.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864918
}}
}}
==PPM1D==
==VCAM1==


* {{medline-title
* {{medline-title
|title=Detectible mosaic truncating [[PPM1D]] mutations, age and breast cancer risk.
|title=Sunitinib facilitates metastatic breast cancer spreading by inducing endothelial cell senescence.
|date=06.2019
|date=29.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30850729
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32993785
|full-text-url=https://sci-hub.do/10.1038/s10038-019-0589-1
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526390
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related remodelling of oesophageal epithelia by mutated cancer drivers.
|title=Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell [[VCAM1]].
|date=01.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30602793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31086348
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0811-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642642
}}
}}
==CYP7A1==
==VCAN==


* {{medline-title
* {{medline-title
|title=Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats.
|title=Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis.
|date=2019
|date=07.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31396457
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31051334
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681801
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495079
}}
}}
* {{medline-title
* {{medline-title
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio).
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.
|date=03.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223
}}
}}
==APPL2==
==WFS1==


* {{medline-title
* {{medline-title
|title=The reversal effect of physical exercise on aging-related increases in [[APPL2]] content in skeletal muscle.
|title=Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila.
|date=01.10.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30189216
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29357349
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2018.09.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794194
}}
}}
* {{medline-title
* {{medline-title
|title=Adaptor Protein [[APPL2]] Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor.
|title=A nonsynonymous mutation in the [[WFS1]] gene in a Finnish family with age-related hearing impairment.
|date=07.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28965332
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28974383
|full-text-url=https://sci-hub.do/10.1007/s12035-017-0785-y
|full-text-url=https://sci-hub.do/10.1016/j.heares.2017.09.013
}}
}}
==ABCA1==
==WIPI2==


* {{medline-title
* {{medline-title
|title=Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension.
|title=Neuronal autophagy declines substantially with age and is rescued by overexpression of [[WIPI2]].
|date=01.07.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31109455
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794336
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.08.027
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984449
}}
}}
* {{medline-title
* {{medline-title
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|date=08.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
}}
}}
==MDH1==
==XRCC1==


* {{medline-title
* {{medline-title
|title=Oxidative Damage to the TCA Cycle Enzyme [[MDH1]] Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain.
|title=[Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats].
|date=03.04.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32175745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30111059
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00861
|full-text-url=https://sci-hub.do/10.19540/j.cnki.cjcmm.20180408.005
}}
}}
* {{medline-title
* {{medline-title
|title=Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro.
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.
|date=08.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977188
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081
}}
}}
==CD22==
==YAP1==


* {{medline-title
* {{medline-title
|title=[[CD22]] blockade restores homeostatic microglial phagocytosis in ageing brains.
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|date=04.2019
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6574119
 
}}
}}
* {{medline-title
* {{medline-title
|title=Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves.
|title=[[YAP1]]-[[LATS2]] feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis.
|date=03.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29624008
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30755404
|full-text-url=https://sci-hub.do/10.24425/119039
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399607
}}
}}
==HSPA1A==
==ZC3H12A==


* {{medline-title
* {{medline-title
|title=Vitamin D3 treatment regulates apoptosis, antioxidant defense system, and DNA integrity in the epididymal sperm of an aged rat model.
|title=Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation.
|date=12.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566824
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31786670
|full-text-url=https://sci-hub.do/10.1002/mrd.23280
|full-text-url=https://sci-hub.do/10.1007/s00109-019-01853-2
}}
}}
* {{medline-title
* {{medline-title
|title=The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells.
|title=Prediction and characterization of human ageing-related proteins by using machine learning.
|date=01.09.2018
|date=06.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29511309
|full-text-url=https://sci-hub.do/10.1556/2060.105.2018.3.20
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840292
}}
}}
==HCRT==
==ZEB1==


* {{medline-title
* {{medline-title
|title=Age-related central regulation of orexin and [[NPY]] in the short-lived African killifish Nothobranchius furzeri.
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|date=15.05.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666646
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|full-text-url=https://sci-hub.do/10.1002/cne.24638
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
}}
}}
==RRM2B==
* {{medline-title
* {{medline-title
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.
|title=Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating [[DNMT1]] via [[ZEB1]].
|date=15.07.2018
|date=16.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29466247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842848
}}
}}
==INPP4B==
==ZEB2==


* {{medline-title
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|title=miR-200b regulates cellular senescence and inflammatory responses by targeting [[ZEB2]] in pulmonary emphysema.
|date=04.2016
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32070140
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
|full-text-url=https://sci-hub.do/10.1080/21691401.2020.1725029
}}
}}
==PDGFRB==
* {{medline-title
* {{medline-title
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|title=MicroRNA-145 induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by [[ZEB2]].
|date=04.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30479019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
|full-text-url=https://sci-hub.do/10.1002/jcp.27521
}}
}}
==CYP2R1==
==ZSCAN10==


* {{medline-title
* {{medline-title
|title=Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance.
|title=RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells.
|date=01.08.2018
|date=10.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955863
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020613
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639470
}}
}}
==CIP2A==
* {{medline-title
* {{medline-title
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|title=[[ZSCAN10]] expression corrects the genomic instability of iPSCs from aged donors.
|date=08.01.2018
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28846095
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843481
}}
}}
==ANGPTL4==
==AACS==


* {{medline-title
* {{medline-title
|title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells.
|title=Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study.
|date=05.2019
|date=07.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33170149
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695390
}}
}}
==FMO3==
==AANAT==


* {{medline-title
* {{medline-title
|title=Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver.
|title=Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis.
|date=11.2017
|date=01.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28819071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697103
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993622
}}
}}
==WLS==
==ABCC9==


* {{medline-title
* {{medline-title
|title=Evaluation of three statistical prediction models for forensic age prediction based on DNA methylation.
|title=TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels.
|date=05.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30682540
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.02.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696921
}}
}}
==BBS5==
==ABCE1==


* {{medline-title
* {{medline-title
|title=Progressive Characterization of Visual Phenotype in Bardet-Biedl Syndrome Mutant Mice.
|title=Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain.
|date=01.03.2019
|date=27.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30901771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485811
|full-text-url=https://sci-hub.do/10.1167/iovs.18-25210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354779
}}
}}
==UCHL1==
==ABCG1==


* {{medline-title
* {{medline-title
|title=Abolishing [[UCHL1]]'s hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice.
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.
|date=04.11.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33159930
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2020.113524
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770
}}
}}
==PLA2G6==
==ABCG5==


* {{medline-title
* {{medline-title
|title=Mutations in the Drosophila homolog of human [[PLA2G6]] give rise to age-dependent loss of psychomotor activity and neurodegeneration.
|title=2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms.
|date=13.02.2018
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29440694
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30939745
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811537
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479705
}}
}}
==FMR1==
==ABHD12==


* {{medline-title
* {{medline-title
|title=Static and dynamic postural control deficits in aging fragile X mental retardation 1 ([[FMR1]]) gene premutation carriers.
|title=Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout [[ABHD12]] Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype.
|date=21.01.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30665341
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31213981
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341725
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555221
}}
}}
==MAP1A==
==ABI3BP==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing [[ABI3BP]] in gallbladder cancer cells.
|date=04.07.2019
|date=07.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174563
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555920
}}
}}
==IL13==
==ABL1==


* {{medline-title
* {{medline-title
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|title=European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia.
|date=07.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32127639
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214240
}}
}}
==DUSP8==
==ABLIM3==


* {{medline-title
* {{medline-title
|title=MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats.
|title=Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization.
|date=12.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31400088
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29529016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826124
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893385
}}
}}
==TNFSF15==
==ACAD10==


* {{medline-title
* {{medline-title
|title=Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=11.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269026
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.09.015
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==FAR2==
==ACAD9==


* {{medline-title
* {{medline-title
|title=[[FAR2]] is associated with kidney disease in mice and humans.
|title=Identification of a novel mitochondrial complex I assembly factor ACDH-12 in Caenorhabditis elegans.
|date=01.08.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29652635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139637
|full-text-url=https://sci-hub.do/10.1016/j.mito.2018.02.010
}}
}}
==NOA1==
==ACADM==


* {{medline-title
* {{medline-title
|title=The dependence of leaf senescence on the balance between 1-aminocyclopropane-1-carboxylate acid synthase 1 (ACS1)-catalysed ACC generation and nitric oxide-associated 1 (NOS1)-dependent NO accumulation in Arabidopsis.
|title=High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats.
|date=07.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30734982
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888352
|full-text-url=https://sci-hub.do/10.1111/plb.12970
|full-text-url=https://sci-hub.do/10.1016/j.jfma.2017.08.008
}}
}}
==SPP1==
==ACAN==


* {{medline-title
* {{medline-title
|title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age.
|title=MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway.
|date=04.2018
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30987676
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769
}}
}}
==TOR2A==
==ACAT2==


* {{medline-title
* {{medline-title
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
|date=05.06.2018
|date=15.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823
}}
}}
==WFIKKN2==
==ACD==


* {{medline-title
* {{medline-title
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.
|title=Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging.
|date=01.01.2019
|date=02.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889148
}}
}}
==ACMSD==
==ACMSD==
Строка 4055: Строка 4007:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448761
}}
}}
==HSD3B2==
==ACO1==


* {{medline-title
* {{medline-title
|title=11-Oxygenated C19 Steroids Do Not Decline With Age in Women.
|title=Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine.
|date=01.07.2019
|date=24.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30690072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525564
|full-text-url=https://sci-hub.do/10.1016/j.jep.2019.01.019
}}
}}
==PREP==
==ACSL5==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Ageing sensitized by iPLA β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids.
|date=12.2017
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888832
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2017.09.001
}}
}}
==OSM==
==ACTA2==


* {{medline-title
* {{medline-title
|title=Age Differences in Sexual Minority Stress and the Importance of Friendship in Later Life.
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|date=04.11.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143546
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|full-text-url=https://sci-hub.do/10.1080/07317115.2020.1836107
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
}}
}}
==UGT2B7==
==ACTR3B==


* {{medline-title
* {{medline-title
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|date=05.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
}}
}}
==EDN1==
==ACVR1==


* {{medline-title
* {{medline-title
|title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway.
|title=Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome.
|date=03.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31998237
|full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966325
}}
}}
==NAIP==
==ADAMTS3==


* {{medline-title
* {{medline-title
|title=Protective effect of xanthohumol against age-related brain damage.
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|date=11.2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
}}
==PIK3C2A==
==ADAMTS9==


* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=15.04.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==NUCB2==
==ADAR==


* {{medline-title
* {{medline-title
|title=Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise Killifish.
|title=Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis.
|date=31.12.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31906085
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29986212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019235
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037660
}}
}}
==ACTR3B==
==ADCK1==


* {{medline-title
* {{medline-title
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|title=Functional analysis of Aarf domain-containing kinase 1 in Drosophila melanogaster.
|date=2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175694
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271681
}}
}}
==HES1==
==ADD2==


* {{medline-title
* {{medline-title
|title=A Single-Cell Transcriptomic Atlas of Human Skin Aging.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=23.11.2020
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33238152
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2020.11.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==DRD1==
==ADH1B==


* {{medline-title
* {{medline-title
|title=Impact of dopamine-related genetic variants on physical activity in old age - a cohort study.
|title=Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde.
|date=24.05.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32448293
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245799
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2018.11.007
}}
}}
==PSMB8==
==ADIPOR1==


* {{medline-title
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|date=04.2016
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
}}
}}
==GP6==
==ADK==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Deletion of pancreatic β-cell adenosine kinase improves glucose homeostasis in young mice and ameliorates streptozotocin-induced hyperglycaemia.
|date=15.11.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044530
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584724
}}
}}
==AOX1==
==ADNP==


* {{medline-title
* {{medline-title
|title=N1-Methylnicotinamide: An Anti-Ovarian Aging Hormetin?
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|date=09.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32711159
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101131
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
}}
}}
==MRO==
==ADNP2==


* {{medline-title
* {{medline-title
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats].
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|date=08.05.2017
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
}}
}}
==LRP1==
==ADORA2B==


* {{medline-title
* {{medline-title
|title=Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome.
|title=Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss.
|date=06.2020
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268785
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33131093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255962
|full-text-url=https://sci-hub.do/10.1096/fj.202000939R
}}
}}
==RXRG==
==ADRA2A==


* {{medline-title
* {{medline-title
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|title=α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway.
|date=2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33116632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574911
}}
}}
==GORAB==
==ADRA2B==


* {{medline-title
* {{medline-title
|title=Examining tissue composition, whole-bone morphology and mechanical behavior of Gorab  mice tibiae: A mouse model of premature aging.
|title=Aging and the Combined effects of [[ADRA2B]] and CB1 deletions on Affective Working Memory.
|date=08.12.2017
|date=11.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29108851
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30858399
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411975
}}
}}
==PABPN1==
==ADRM1==


* {{medline-title
* {{medline-title
|title=Dysfunctional transcripts are formed by alternative polyadenylation in OPMD.
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
|date=26.09.2017
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088723
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498
}}
}}
==CBX8==
==AGAP2==


* {{medline-title
* {{medline-title
|title=[[PIM1]]-catalyzed [[CBX8]] phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast.
|title=Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating [[AGAP2]].
|date=27.06.2018
|date=05.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29763603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386624
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.05.070
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710058
}}
}}
==BAG3==
==AHCY==


* {{medline-title
* {{medline-title
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=03.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
==KCNAB3==
==AIDA==


* {{medline-title
* {{medline-title
|title=Tracking age-correlated DNA methylation markers in the young.
|title=Identification of Postharvest Senescence Regulators Through Map-Based Cloning Using Detached Arabidopsis Inflorescences as a Model Tissue.
|date=09.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29933125
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392668
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.06.011
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-7672-0_17
}}
}}
==SRSF3==
==AIF1==


* {{medline-title
* {{medline-title
|title=Alternative polyadenylation dependent function of splicing factor [[SRSF3]] contributes to cellular senescence.
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|date=04.03.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30835716
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
}}
}}
==NGFR==
==AKAP12==


* {{medline-title
* {{medline-title
|title=Evidence for changing nerve growth factor signalling mechanisms during development, maturation and ageing in the rat molar pulp.
|title=A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter.
|date=02.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30099752
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29314444
|full-text-url=https://sci-hub.do/10.1111/iej.12997
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918158
}}
}}
==COQ7==
==AKAP17A==


* {{medline-title
* {{medline-title
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|date=18.09.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
}}
}}
==GPX2==
==AKT2==


* {{medline-title
* {{medline-title
|title=RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=10.10.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020613
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639470
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
==PRKCH==
==AKT3==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma.
|date=15.11.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097674
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135677
}}
}}
==FASN==
==AKTIP==


* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits.
|date=08.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29635765
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052474
}}
}}
==SAT1==
==ALAS1==


* {{medline-title
* {{medline-title
|title=Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action.
|title=Heterozygous disruption of [[ALAS1]] in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver.
|date=08.2020
|date=08.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544364
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33307066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469548
|full-text-url=https://sci-hub.do/10.1016/j.abb.2020.108721
}}
}}
==GADD45B==
==ALDH3A1==


* {{medline-title
* {{medline-title
|title=Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging?
|title=Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs).
|date=2019
|date=13.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156709
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382415
}}
}}
==SALL1==
==ALDOA==


* {{medline-title
* {{medline-title
|title=[[SALL1]] functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex.
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|date=06.04.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29625565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889587
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
}}
}}
==LRP2==
==ALK==


* {{medline-title
* {{medline-title
|title=Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis.
|title=Catalog of Lung Cancer Gene Mutations Among Chinese Patients.
|date=27.11.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485812
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850378
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.11.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417348
}}
}}
==PDK4==
==ALKBH1==


* {{medline-title
* {{medline-title
|title=Putrescine delays postovulatory aging of mouse oocytes by upregulating [[PDK4]] expression and improving mitochondrial activity.
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|date=16.12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554191
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326651
 
}}
}}
==TRIM28==
==ALKBH2==


* {{medline-title
* {{medline-title
|title=Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau.
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|date=04.06.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29863470
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993537
}}
==RRAD==


* {{medline-title
|title=Pan-senescence transcriptome analysis identified [[RRAD]] as a marker and negative regulator of cellular senescence.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391675
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.10.457
}}
}}
==ECRG4==
==ALOX12==


* {{medline-title
* {{medline-title
|title=[[ECRG4]]: a new potential target in precision medicine.
|title=Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer.
|date=10.2019
|date=15.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32265301
|full-text-url=https://sci-hub.do/10.1007/s11684-018-0637-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242692
}}
}}
==COL6A1==
==ALOX5==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme.
|date=10.2019
|date=01.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.1089/ars.2019.7751
}}
}}
==FSTL1==
==AMFR==


* {{medline-title
* {{medline-title
|title=Blocking the [[FSTL1]]-[[DIP2A]] Axis Improves Anti-tumor Immunity.
|title=Mice heterozygous for the Cdh23/Ahl1 mutation show age-related deficits in auditory temporal processing.
|date=14.08.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30110636
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247458
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.07.043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732241
}}
}}
==CREB5==
==AMHR2==


* {{medline-title
* {{medline-title
|title=Cellular senescence induces replication stress with almost no affect on DNA replication timing.
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|date=2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963964
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
}}
}}
==MTRR==
==AMPH==


* {{medline-title
* {{medline-title
|title=One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults.
|title=Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood.
|date=12.2019
|date=01.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208817
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29792867
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.05.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026035
}}
}}
==FADD==
==ANG==


* {{medline-title
* {{medline-title
|title=Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal [[FADD]].
|title=Age-related differences in the cutaneous vascular response to exogenous angiotensin II.
|date=11.2018
|date=01.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30138765
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30499715
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.07.014
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00509.2018
}}
}}
==SND1==
==ANGPT2==


* {{medline-title
* {{medline-title
|title=[Downregulation of [[SND1]] Expression Accelerates Cell Senescence of Human Diploid Fibroblasts 2BS via Modulating the SASP].
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|date=05.2020
|date=14.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32543144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|full-text-url=https://sci-hub.do/10.12182/20200560504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
}}
}}
==DDR1==
==ANGPTL4==


* {{medline-title
* {{medline-title
|title=Age-related modifications of type I collagen impair [[DDR1]]-induced apoptosis in non-invasive breast carcinoma cells.
|title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells.
|date=2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733741
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363044
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x
}}
}}
==ST18==
==ANK2==


* {{medline-title
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=04.2016
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==TGM2==
==ANK3==


* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Age-related atrophy of cortical thickness and genetic effect of [[ANK3]] gene in first episode MDD patients.
|date=11.2018
|date=26.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32911427
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490581
}}
}}
==SP1==
==ANKS1B==


* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|date=15.04.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
}}
==CIZ1==
==ANPEP==


* {{medline-title
* {{medline-title
|title=DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice.
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity.
|date=02.2018
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154038
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877805
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174
}}
}}
==RORA==
==ANXA1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging.
|date=15.11.2018
|date=26.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848
}}
}}
==FOXP2==
==AOX1==


* {{medline-title
* {{medline-title
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.
|title=N1-Methylnicotinamide: An Anti-Ovarian Aging Hormetin?
|date=06.11.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32711159
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247
|full-text-url=https://sci-hub.do/10.1016/j.arr.2020.101131
}}
}}
==STC2==
==AP2B1==


* {{medline-title
* {{medline-title
|title=Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and [[STC2]].
|title=Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice.
|date=05.12.2019
|date=20.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31761296
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31860870
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904802
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949063
}}
}}
==CXCR5==
==APLNR==


* {{medline-title
* {{medline-title
|title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses.
|title=Endothelial [[APLNR]] regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.
|date=17.08.2017
|date=13.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904225
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703224
}}
}}
==DDR2==
==APLP2==


* {{medline-title
* {{medline-title
|title=Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging.
|title=Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex.
|date=03.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833185
|full-text-url=https://sci-hub.do/10.1007/s11064-018-2669-6
}}
}}
==DBH==
==APOA1==


* {{medline-title
* {{medline-title
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children.
|title=Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I.
|date=04.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29623474
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711
|full-text-url=https://sci-hub.do/10.1007/s10534-018-0101-y
}}
}}
==NMUR1==
==APOBEC1==


* {{medline-title
* {{medline-title
|title=[Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules].
|title=Loss of [[APOBEC1]] RNA-editing function in microglia exacerbates age-related CNS pathophysiology.
|date=2019
|date=12.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31685733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167375
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740644
}}
}}
==TXN==
==APOC1==


* {{medline-title
* {{medline-title
|title=Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice.
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|date=15.11.2017
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29141658
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688691
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
}}
}}
==HJV==
==APOC3==


* {{medline-title
* {{medline-title
|title=Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting.
|title=Positional Obstructive Sleep Apnea Syndrome in Elderly Patients.
|date=06.2019
|date=10.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884219
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32050596
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042812
}}
}}
==TP73==
==APPL1==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Insulin and adipokine signaling and their cross-regulation in postmortem human brain.
|date=15.11.2017
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31539648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960343
}}
}}
==MICB==
==AQP2==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=A bell-shaped pattern of urinary aquaporin-2-bearing extracellular vesicle release in an experimental model of nephronophthisis.
|date=10.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509436
}}
}}
==PTN==
==AQP4==


* {{medline-title
* {{medline-title
|title=Connecting Metainflammation and Neuroinflammation Through the [[PTN]]-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development.
|title=Overexpression of Slit2 improves function of the paravascular pathway in the aging mouse brain.
|date=2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31031625
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30085336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474308
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108881
}}
}}
==MCM3==
==AQP5==


* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=Submandibular gland-specific inflammaging-induced hyposalivation in the male senescence-accelerated mouse prone -1 line (SAM-P1).
|date=27.07.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684147
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09797-3
}}
}}
==UCN==
==ARHGAP18==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma
|date=15.11.2018
|date=18.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327185
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863019
}}
}}
==IGFBP7==
==ARID1B==


* {{medline-title
* {{medline-title
|title=Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7.
|title=A 69-year-old woman with Coffin-Siris syndrome.
|date=03.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31904196
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031646
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.38844
}}
}}
==KLF2==
==ARID5A==


* {{medline-title
* {{medline-title
|title=[[KLF2]] induces the senescence of pancreatic cancer cells by cooperating with FOXO4 to upregulate p21.
|title=Differentially regulated gene expression in quiescence versus senescence and identification of [[ARID5A]] as a quiescence associated marker.
|date=01.03.2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31866399
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29044508
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2019.111784
|full-text-url=https://sci-hub.do/10.1002/jcp.26227
}}
}}
==LIPA==
==ARL13B==


* {{medline-title
* {{medline-title
|title=Influence of Habitual Physical Behavior - Sleeping, Sedentarism, Physical Activity - On Bone Health in Community-Dwelling Older People.
|title=[[ARL13B]], a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments.
|date=2019
|date=20.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31037056
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573647
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476278
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381253
}}
}}
==SMARCB1==
==ARNTL==


* {{medline-title
* {{medline-title
|title=High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=17.10.2017
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29045843
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2017.09.085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
==IP6K1==
==ARNTL2==


* {{medline-title
* {{medline-title
|title=The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=2019
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552262
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746962
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
==NBR1==
==ARRB2==


* {{medline-title
* {{medline-title
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
|title=Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity.
|date=03.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304635
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801044
}}
}}
==PPP2R3C==
==ARSA==


* {{medline-title
* {{medline-title
|title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=04.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==CFH==
==ASB3==


* {{medline-title
* {{medline-title
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye.
|title=Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.
|date=13.06.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818258
}}
}}
==USP8==
==ASB7==


* {{medline-title
* {{medline-title
|title=Inhibition of the deubiquitinase [[USP8]] corrects a Drosophila [[PINK1]] model of mitochondria dysfunction.
|title=[[ASB7]] Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation.
|date=04.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33251222
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467245
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674779
}}
}}
==PRNP==
==ASIP==


* {{medline-title
* {{medline-title
|title=Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS.
|title=Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation.
|date=06.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32516343
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222197
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282622
|full-text-url=https://sci-hub.do/10.1111/ics.12494
}}
}}
==SV2B==
==ASMT==


* {{medline-title
* {{medline-title
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|title=The influence of ageing on the extrapineal melatonin synthetic pathway.
|date=10.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29906492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.06.010
}}
}}
==CCN4==
==ASPA==


* {{medline-title
* {{medline-title
|title=CCN proteins as potential actionable targets in scleroderma.
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|date=01.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30329180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|full-text-url=https://sci-hub.do/10.1111/exd.13806
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
}}
}}
==BANF1==
==ATF2==


* {{medline-title
* {{medline-title
|title=An additional case of Néstor-Guillermo progeria syndrome diagnosed in early childhood.
|title=Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium.
|date=10.2020
|date=01.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32783369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360953
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.61777
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915954
}}
}}
==TNP2==
==ATF3==


* {{medline-title
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|title=[[ATF3]] represses [[PINK1]] gene transcription in lung epithelial cells to control mitochondrial homeostasis.
|date=01.02.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29363258
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866
}}
}}
==SMYD2==
==ATF7==


* {{medline-title
* {{medline-title
|title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity.
|title=Stress-induced and [[ATF7]]-dependent epigenetic change influences cellular senescence.
|date=10.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31294895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115
|full-text-url=https://sci-hub.do/10.1111/gtc.12713
}}
}}
==GDF9==
==ATG10==


* {{medline-title
* {{medline-title
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|title=Genetic associations with age of menopause in familial longevity.
|date=18.10.2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==KLF5==
==ATG16L1==


* {{medline-title
* {{medline-title
|title=[[EGR1]] promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling.
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|date=01.09.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201921
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.06.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
}}
}}
==BTC==
==ATG4B==


* {{medline-title
* {{medline-title
|title=Behavioral tagging and capture: long-term memory decline in middle-aged rats.
|title=Impaired autophagic activity and [[ATG4B]] deficiency are associated with increased endoplasmic reticulum stress-induced lung injury.
|date=07.2018
|date=27.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29609080
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30147026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964067
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128419
}}
}}
==BARD1==
==ATG4D==


* {{medline-title
* {{medline-title
|title=BRCA1 and [[BARD1]] mediate apoptotic resistance but not longevity upon mitochondrial stress in [i]Caenorhabditis elegans[/i].
|title=Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats.
|date=12.2018
|date=17.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30366941
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280797
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b02567
}}
}}
==PEBP1==
==ATP1A2==


* {{medline-title
* {{medline-title
|title=[i]Drosophila[/i] [[PEBP1]] inhibits intestinal stem cell aging via suppression of ERK pathway.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=06.04.2018
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719584
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915051
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==NMI==
==ATP2B1==


* {{medline-title
* {{medline-title
|title=Age-Dependent Control of Shoulder Muscles During a Reach-and-Lift Task.
|title=Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries.
|date=10.12.2019
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31825888
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28795531
|full-text-url=https://sci-hub.do/10.1123/japa.2019-0055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595685
}}
}}
==TAF7==
==ATP6V0C==


* {{medline-title
* {{medline-title
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|date=22.01.2020
|date=07.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
}}
}}
==NLRX1==
==ATP6V1E1==


* {{medline-title
* {{medline-title
|title=NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=26.02.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828065
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==HHLA2==
==ATXN1==


* {{medline-title
* {{medline-title
|title=Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma.
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=05.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30768970
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://sci-hub.do/10.1016/j.jtho.2019.01.024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
}}
==WT1==
==ATXN3==


* {{medline-title
* {{medline-title
|title=Age and weight at first mating affects plasma leptin concentration but no effects on reproductive performance of gilts.
|title=Rescue of [[ATXN3]] neuronal toxicity in [i]Caenorhabditis[/i][i]elegans[/i] by chemical modification of endoplasmic reticulum stress.
|date=09.2019
|date=19.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31602307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29061563
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778857
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769603
}}
}}
==PPARG==
==AXL==


* {{medline-title
* {{medline-title
|title=The [[PPARG]] Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity.
|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells.
|date=04-06.2018
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29116943
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938164
|full-text-url=https://sci-hub.do/10.1111/pcmr.12811
}}
}}
==PTK7==
==BACH2==


* {{medline-title
* {{medline-title
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|title=Age-related changes in the [[BACH2]] and [[PRDM1]] genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.
|date=05.07.2018
|date=17.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337793
}}
}}
==VASH1==
==BAG3==


* {{medline-title
* {{medline-title
|title=Double-Face of Vasohibin-1 for the Maintenance of Vascular Homeostasis and Healthy Longevity.
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
|date=01.06.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29398681
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049
}}
}}
==TRAV27==
==BANF1==


* {{medline-title
* {{medline-title
|title=Perturbed CD8  T cell immunity across universal influenza epitopes in the elderly.
|title=An additional case of Néstor-Guillermo progeria syndrome diagnosed in early childhood.
|date=02.2018
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32783369
|full-text-url=https://sci-hub.do/10.1189/jlb.5MA0517-207R
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.61777
}}
}}
==ACSL5==
==BARD1==


* {{medline-title
* {{medline-title
|title=Ageing sensitized by iPLA β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids.
|title=BRCA1 and [[BARD1]] mediate apoptotic resistance but not longevity upon mitochondrial stress in [i]Caenorhabditis elegans[/i].
|date=12.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888832
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30366941
|full-text-url=https://sci-hub.do/10.1016/j.bbalip.2017.09.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280797
}}
}}
==HNRNPA0==
==BAZ1A==


* {{medline-title
* {{medline-title
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells.
|date=10.2019
|date=15.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023
}}
}}
==MCF2L==
==BAZ2B==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Two conserved epigenetic regulators prevent healthy ageing.
|date=25.07.2018
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32103178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2037-y
}}
}}
==ALOX12==
==BBS5==


* {{medline-title
* {{medline-title
|title=Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer.
|title=Progressive Characterization of Visual Phenotype in Bardet-Biedl Syndrome Mutant Mice.
|date=15.05.2020
|date=01.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32265301
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30901771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242692
|full-text-url=https://sci-hub.do/10.1167/iovs.18-25210
}}
}}
==RARB==
==BCAS1==


* {{medline-title
* {{medline-title
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
|title=Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs).
|date=12.2019
|date=13.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382415
}}
}}
==COL1A1==
==BCL11B==


* {{medline-title
* {{medline-title
|title=Remodeling process in bone of aged rats in response to resistance training.
|title=Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells.
|date=01.09.2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593709
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360511
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989724
}}
}}
==ATF2==
==BCL2L1==
 
* {{medline-title
|title=Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium.
|date=01.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360953
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915954
}}
==USF2==
 
* {{medline-title
|title=Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice.
|date=15.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30084918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454504
}}
==CLN3==


* {{medline-title
* {{medline-title
Строка 4847: Строка 4775:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==GNAQ==
==BCL2L11==


* {{medline-title
* {{medline-title
|title=[[GNAQ]]  expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system.
|title=miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence.
|date=01.2020
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31680437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074095
|full-text-url=https://sci-hub.do/10.1111/pcmr.12843
|full-text-url=https://sci-hub.do/10.1002/jcb.28862
}}
}}
==MC1R==
==BHLHE40==


* {{medline-title
* {{medline-title
|title=In vitro behavior and UV response of melanocytes derived from carriers of [[[[CDKN2A]]]] mutations and [[MC1R]] variants.
|title=Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1.
|date=03.2019
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117292
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32360904
|full-text-url=https://sci-hub.do/10.1111/pcmr.12732
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105689
}}
}}
==ERCC5==
==BMP6==


* {{medline-title
* {{medline-title
|title=Identification of a [[ERCC5]] c.2333T>C (L778P) Variant in Two Tunisian Siblings With Mild Xeroderma Pigmentosum Phenotype.
|title=Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology.
|date=2019
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30838033
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383105
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233090
}}
}}
==S1PR3==
==BMP7==


* {{medline-title
* {{medline-title
|title=Sexual dimorphism of metabolic and vascular dysfunction in aged mice and those lacking the sphingosine 1-phosphate receptor 3.
|title=Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting [[BMP7]].
|date=01.12.2017
|date=11.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28943478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31829291
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907335
}}
}}
==SATB2==
==BMPR1B==


* {{medline-title
* {{medline-title
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|title=Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes.
|date=06.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503129
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.08.018
}}
}}
==SELENOK==
==BMPR2==


* {{medline-title
* {{medline-title
|title=Dietary selenium deficiency and supplementation differentially modulate the expression of two ER-resident selenoproteins (selenoprotein K and selenoprotein M) in the ovaries of aged mice: Preliminary data.
|title=Centenarians Overexpress Pluripotency-Related Genes.
|date=09.2020
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736983
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|full-text-url=https://sci-hub.do/10.1016/j.repbio.2020.07.006
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
}}
}}
==GAB2==
==BNC1==


* {{medline-title
* {{medline-title
|title=Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936.
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|date=01.12.2017
|date=22.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29207374
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764388
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
}}
}}
==ITGA3==
==BOC==


* {{medline-title
* {{medline-title
|title=A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells.
|title=Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations.
|date=17.08.2020
|date=01.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32807231
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32140711
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430027
|full-text-url=https://sci-hub.do/10.1093/jn/nxaa031
}}
}}
==NRM==
==BRD2==


* {{medline-title
* {{medline-title
|title=Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation.
|title=Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice.
|date=12.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31445185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32559200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192097
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304595
}}
}}
==PRM2==
==BRD3==


* {{medline-title
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke.
|date=01.02.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004
}}
}}
==DLAT==
==BTC==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Behavioral tagging and capture: long-term memory decline in middle-aged rats.
|date=02.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29609080
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964067
}}
}}
==ACAT2==
==BTG1==


* {{medline-title
* {{medline-title
|title=Serum starvation of A[[RPE]]-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
|title=Tumor cell escape from therapy-induced senescence.
|date=15.12.2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29097185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576620
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701823
|full-text-url=https://sci-hub.do/10.1016/j.bcp.2018.12.013
}}
}}
==UBTF==
==C2CD2==


* {{medline-title
* {{medline-title
|title=Age-associated dysregulation of protein metabolism in the mammalian oocyte.
|title=Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort.
|date=12.2017
|date=20.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994181
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29158487
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676066
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696534
}}
}}
==WFIKKN1==
==CA12==


* {{medline-title
* {{medline-title
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|date=01.01.2019
|date=26.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
}}
}}
==GSTM3==
==CABLES1==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=[[CABLES1]] Deficiency Impairs Quiescence and Stress Responses of Hematopoietic Stem Cells in Intrinsic and Extrinsic Manners.
|date=12.2018
|date=13.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700604
}}
}}
==YES1==
==CACNA1B==


* {{medline-title
* {{medline-title
|title=Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=20.10.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30341976
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224233
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==GSN==
==CACNA1S==


* {{medline-title
* {{medline-title
|title=Oral administration of alcalase potato protein hydrolysate-APPH attenuates high fat diet-induced cardiac complications via TGF-β/[[GSN]] axis in aging rats.
|title=Increased calcium channel in the lamina propria of aging rat.
|date=01.2019
|date=31.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30240538
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31682233
|full-text-url=https://sci-hub.do/10.1002/tox.22651
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834399
}}
}}
==RB1==
==CALR==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender.
|date=15.11.2017
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0
}}
}}
==MR1==
==CAMSAP1==


* {{medline-title
* {{medline-title
|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers.
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|date=05.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
}}
}}
==LRP8==
==CAP2==


* {{medline-title
* {{medline-title
|title=SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating [[LRP8]] and ApoE.
|title=Targeting MRTF/[[SRF]] in [[CAP2]]-dependent dilated cardiomyopathy delays disease onset.
|date=02.07.2019
|date=21.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31269452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30762586
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.06.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483011
}}
}}
==HLA-DMA==
==CAPRIN1==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Reduced Levels of the Synaptic Functional Regulator FMRP in Dentate Gyrus of the Aging Sprague-Dawley Rat.
|date=10.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29218006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703695
}}
}}
==OOEP==
==CARF==


* {{medline-title
* {{medline-title
|title=Maternal gene [i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes.
|title=Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
|date=18.11.2018
|date=22.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31112603
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085769
|full-text-url=https://sci-hub.do/10.1093/gerona/glz077
}}
}}
==ACAN==
==CARM1==


* {{medline-title
* {{medline-title
|title=MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway.
|title=[[CARM1]] regulates senescence during airway epithelial cell injury in COPD pathogenesis.
|date=15.04.2019
|date=01.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30987676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31461302
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466769
|full-text-url=https://sci-hub.do/10.1152/ajplung.00441.2018
}}
}}
==SOX13==
==CASK==


* {{medline-title
* {{medline-title
|title=In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases.
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats.
|date=12.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09834-1
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001
}}
}}
==TOP1==
==CASP3==


* {{medline-title
* {{medline-title
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|title=Does cartilage ERα overexpression correlate with osteoarthritic chondrosenescence? Indications from [i]Labisia pumila[/i] OA mitigation.
|date=12.06.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31502578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
 
}}
}}
==ST6GAL1==
==CASS4==


* {{medline-title
* {{medline-title
|title=Glycobiology of Aging.
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30779020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://sci-hub.do/10.1007/978-981-13-2835-0_17
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
}}
==HSP90AA1==
==CAV1==


* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine.
|date=09.2017
|date=24.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30690072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://sci-hub.do/10.1016/j.jep.2019.01.019
}}
}}
==ZNF467==
==CBX3==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development.
|date=15.11.2018
|date=24.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32979540
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115659
}}
}}
==CYP26A1==
==CBX4==


* {{medline-title
* {{medline-title
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|title=Maintenance of Nucleolar Homeostasis by [[CBX4]] Alleviates Senescence and Osteoarthritis.
|date=08.10.2018
|date=26.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30917318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.02.088
}}
}}
==SDC4==
==CBX8==


* {{medline-title
* {{medline-title
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|title=[[PIM1]]-catalyzed [[CBX8]] phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast.
|date=01.10.2017
|date=27.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29763603
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.05.070
}}
}}
==RPA2==
==CCAR2==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans.
|date=11.2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500
}}
}}
==HSPG2==
==CCDC88A==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=02.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==NEK2==
==CCL13==


* {{medline-title
* {{medline-title
|title=Upregulation of [[FOXM1]] leads to diminished drug sensitivity in myeloma.
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|date=21.11.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249818
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
}}
}}
==MAOA==
==CCL18==


* {{medline-title
* {{medline-title
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|date=05.10.2017
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
}}
}}
==HSPB1==
==CCL19==


* {{medline-title
* {{medline-title
|title=The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity.
|title=Age-Related Gliosis Promotes Central Nervous System Lymphoma through [[CCL19]]-Mediated Tumor Cell Retention.
|date=06.2019
|date=16.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102684
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31526758
|full-text-url=https://sci-hub.do/10.1016/j.diabres.2019.05.009
|full-text-url=https://sci-hub.do/10.1016/j.ccell.2019.08.001
}}
}}
==LTF==
==CCL28==


* {{medline-title
* {{medline-title
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|title=Age-related chemokine alterations affect IgA secretion and gut immunity in female mice.
|date=03.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32277312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09877-9
}}
}}
==EID3==
==CCN4==


* {{medline-title
* {{medline-title
|title=Upregulation of [[EID3]] sensitizes breast cancer cells to ionizing radiation-induced cellular senescence.
|title=CCN proteins as potential actionable targets in scleroderma.
|date=11.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30114644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30329180
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.08.022
|full-text-url=https://sci-hub.do/10.1111/exd.13806
}}
}}
==GRM3==
==CCNA1==


* {{medline-title
* {{medline-title
|title=Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk.
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
|date=04.2020
|date=02.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32203495
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919
|full-text-url=https://sci-hub.do/10.1038/s41593-020-0604-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654
}}
}}
==USP7==
==CCNA2==


* {{medline-title
* {{medline-title
|title=Deubiquitinase [[USP7]] regulates [i]Drosophila[/i] aging through ubiquitination and autophagy.
|title=Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan.
|date=20.11.2020
|date=31.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33221768
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463071
|full-text-url=https://sci-hub.do/10.18632/aging.104067
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881094
}}
}}
==JAK3==
==CCND1==


* {{medline-title
* {{medline-title
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|title=Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells.
|date=04.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592933
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
|full-text-url=https://sci-hub.do/10.1016/j.archoralbio.2020.104819
}}
}}
==ULK2==
==CCND2==


* {{medline-title
* {{medline-title
|title=miR-26a suppresses autophagy in swine Sertoli cells by targeting [[ULK2]].
|title=Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma.
|date=08.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29761550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097674
|full-text-url=https://sci-hub.do/10.1111/rda.13177
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135677
}}
}}
==SPHK1==
==CCND3==


* {{medline-title
* {{medline-title
|title=Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina.
|title=The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells.
|date=10.2019
|date=29.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30997640
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32727592
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425817
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392710
}}
}}
==CTC1==
==CCR3==


* {{medline-title
* {{medline-title
|title=[[CTC1]]-[[STN1]] coordinates G- and C-strand synthesis to regulate telomere length.
|title=Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro.
|date=08.2018
|date=04.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32033185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036885
}}
}}
==CXCL16==
==CD2==


* {{medline-title
* {{medline-title
|title=[[CXCR6]] Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and [[CD4]]  T-Cell-Dependent Control of Senescence.
|title=Adaptive NKG2C CD57  Natural Killer Cell and Tim-3 Expression During Viral Infections.
|date=05.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710528
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731749
|full-text-url=https://sci-hub.do/10.1053/j.gastro.2019.01.247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919961
}}
}}
==ENTPD7==
==CD209==


* {{medline-title
* {{medline-title
|title=Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 ([[ENTPD7]]).
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|date=23.08.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31443651
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
}}
}}
==P2RY10==
==CD226==


* {{medline-title
* {{medline-title
|title=Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury.
|title=T-cell Immunoglobulin and ITIM Domain Contributes to CD8  T-cell Immunosenescence.
|date=12.06.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189983
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29349889
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561964
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847879
}}
}}
==IFNG==
==CD2AP==


* {{medline-title
* {{medline-title
|title=Glutathione Peroxidase 3 Delivered by hiPSC-[[MSC]]s Ameliorated Hepatic IR Injury via Inhibition of Hepatic Senescence.
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=2018
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29290803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743470
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
==PTTG1==
==CD48==


* {{medline-title
* {{medline-title
|title=[Down-regulated [[PTTG1]] expression promotes the senescence of human prostate cancer LNCaP-AI].
|title=Genetic overexpression of [[COMP]]-Ang1 impairs BM microenvironment and induces senescence of BM HSCs.
|date=03.2019
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32216239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604278
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.210
}}
==CD55==


* {{medline-title
|title=Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303009
}}
}}
==CYP1B1==
==CD59==


* {{medline-title
* {{medline-title
|title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts.
|title=Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria.
|date=04.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156458
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529780
}}
}}
==MCM6==
==CD72==


* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation.
|date=27.07.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930899
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428705
}}
}}
==LMX1A==
==CD82==


* {{medline-title
* {{medline-title
|title=Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain.
|title=Cell-surface phenotyping identifies [[CD36]] and CD97 as novel markers of fibroblast quiescence in lung fibrosis.
|date=13.11.2018
|date=01.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30318292
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952218
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234859
|full-text-url=https://sci-hub.do/10.1152/ajplung.00439.2017
}}
}}
==POLL==
==CDC20==


* {{medline-title
* {{medline-title
|title=Temporal trends in loss of life expectancy after a cancer diagnosis among the Australian population.
|title=Premature aging syndrome showing random chromosome number instabilities with [[CDC20]] mutation.
|date=04.2020
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32062407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33094908
|full-text-url=https://sci-hub.do/10.1016/j.canep.2020.101686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681047
}}
}}
==TGFB1==
==CDC25A==


* {{medline-title
* {{medline-title
|title=Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease.
|title=Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage.
|date=11.2017
|date=10.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28812215
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665708
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600899
}}
}}
==IFIT1==
==CDC6==


* {{medline-title
* {{medline-title
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|title=A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.
|date=06.2018
|date=10.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29321003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763532
}}
}}
==UBE2E3==
==CDC73==


* {{medline-title
* {{medline-title
|title=Loss of the ubiquitin conjugating enzyme [[UBE2E3]] induces cellular senescence.
|title=Down-regulation of cancer-associated gene [[CDC73]] contributes to cellular senescence.
|date=07.2018
|date=23.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29879550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29621547
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007080
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.228
}}
}}
==PAX7==
==CDH1==


* {{medline-title
* {{medline-title
|title=Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits.
|title=Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation.
|date=10.2018
|date=15.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30006671
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32010971
|full-text-url=https://sci-hub.do/10.1007/s00421-018-3943-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496346
}}
}}
==PTPRR==
==CDH2==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type.
|date=15.11.2018
|date=30.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102368
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265269
}}
}}
==ABCC9==
==CDKN1B==


* {{medline-title
* {{medline-title
|title=TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels.
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|date=05.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30682540
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696921
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
}}
}}
==NFATC1==
==CDKN1C==


* {{medline-title
* {{medline-title
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|date=02.10.2017
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
}}
}}
==EIF4E==
==CDO1==


* {{medline-title
* {{medline-title
|title=Transcriptomic evidence that insulin signalling pathway regulates the ageing of subterranean termite castes.
|title=The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway.
|date=18.05.2020
|date=19.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424344
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235038
|full-text-url=https://sci-hub.do/10.1039/c8fo00740c
}}
}}
==SCAMP4==
==CDR1==


* {{medline-title
* {{medline-title
|title=[[SCAMP4]] enhances the senescent cell secretome.
|title=Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires.
|date=01.07.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967290
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786517
}}
}}
==MYSM1==
==CDX2==


* {{medline-title
* {{medline-title
|title=[[MYSM1]] Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan.
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|date=11.2020
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33240758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675055
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
}}
}}
==INHBA==
==CEBPB==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=02.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
}}
==BTG1==
==CEBPD==


* {{medline-title
* {{medline-title
|title=Tumor cell escape from therapy-induced senescence.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=04.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576620
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://sci-hub.do/10.1016/j.bcp.2018.12.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==OMD==
==CEL==


* {{medline-title
* {{medline-title
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|title=Nanocarrier-Mediated Chemo-Immunotherapy Arrested Cancer Progression and Induced Tumor Dormancy in Desmoplastic Melanoma.
|date=06.02.2019
|date=28.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30016071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115293
}}
}}
==IMMP2L==
==CES1==


* {{medline-title
* {{medline-title
|title=Switching off [[IMMP2L]] signaling drives senescence via simultaneous metabolic alteration and blockage of cell death.
|title=[Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog].
|date=06.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31061351
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993829
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00228
}}
}}
==TRIB2==
==CETP==


* {{medline-title
* {{medline-title
|title=[[TRIB2]] functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling.
|title=Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study.
|date=12.12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30159092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291992
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080062
}}
==CFB==
 
* {{medline-title
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye.
|date=13.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230
}}
==CFH==
 
* {{medline-title
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye.
|date=13.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230
}}
}}
==ABLIM3==
==CHAT==


* {{medline-title
* {{medline-title
|title=Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization.
|title=Satisfaction and Technology Evaluation of a Telehealth Robotic Program to Optimize Healthy Independent Living for Older Adults.
|date=05.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29529016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320967
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893385
|full-text-url=https://sci-hub.do/10.1111/jnu.12436
}}
}}
==USF1==
==CHEK2==


* {{medline-title
* {{medline-title
|title=The rs2516839 variation of [[USF1]] gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+ study.
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=01.2019
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30203836
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://sci-hub.do/10.1111/ahg.12282
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
==ASMT==
==CHIA==


* {{medline-title
* {{medline-title
|title=The influence of ageing on the extrapineal melatonin synthetic pathway.
|title=Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets.
|date=09.2018
|date=26.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29906492
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30486328
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.06.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316572
}}
}}
==ERBB4==
==CHL1==


* {{medline-title
* {{medline-title
|title=Overexpression of [[ERBB4]] rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
|title=Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B.
|date=03.2019
|date=07.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182634
|full-text-url=https://sci-hub.do/10.1096/fj.201801690R
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687901
}}
}}
==CHRNE==
==CHRM4==


* {{medline-title
* {{medline-title
Строка 5423: Строка 5375:
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==CPT1B==
==CHRNA7==


* {{medline-title
* {{medline-title
|title=Effects of carnitine palmitoyltransferases on cancer cellular senescence.
|title=Associations between genetic variations and global motion perception.
|date=02.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30070697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31432227
|full-text-url=https://sci-hub.do/10.1002/jcp.27042
|full-text-url=https://sci-hub.do/10.1007/s00221-019-05627-7
}}
}}
==CNP==
==CHRNE==


* {{medline-title
* {{medline-title
|title=Environmental Enrichment Elicits a Transient Rise of Bioactive C-Type Natriuretic Peptide in Young but Not Aged Rats.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30072880
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060231
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==MCAT==
==CHSY1==


* {{medline-title
* {{medline-title
|title=Small molecules as therapeutic drugs for Alzheimer's disease.
|title=Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in [i]skt[/i] Mice.
|date=04.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30877034
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944401
}}
}}
==ALKBH2==
==CINP==


* {{medline-title
* {{medline-title
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|title=Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging.
|date=2018
|date=01-03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30681437
 
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000294
}}
}}
==SELENOP==
==CIP2A==


* {{medline-title
* {{medline-title
|title=Analyses of Selenotranscriptomes and Selenium Concentrations in Response to Dietary Selenium Deficiency and Age Reveal Common and Distinct Patterns by Tissue and Sex in Telomere-Dysfunctional Mice.
|title=Inhibition of [[CIP2A]] attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma.
|date=10.2017
|date=08.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28855418
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175329
|full-text-url=https://sci-hub.do/10.3945/jn.117.247775
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2017.11.124
}}
}}
==ELF3==
==CIZ1==


* {{medline-title
* {{medline-title
|title=High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in [i]Arabidopsis[/i].
|title=DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice.
|date=31.07.2020
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32732458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29154038
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398796
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877805
}}
}}
==SCN9A==
==CLEC3B==


* {{medline-title
* {{medline-title
|title=The [[SCN9A]] channel and plasma membrane depolarization promote cellular senescence through Rb pathway.
|title=[[CLEC3B]] p.S106G Mutant in a Caucasian Population of Successful Neurological Aging.
|date=06.2018
|date=16.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29446526
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570938
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946064
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494029
}}
}}
==ZBTB16==
==CLEC4E==


* {{medline-title
* {{medline-title
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|date=06.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
}}
}}
==NDUFV2==
==CLN3==


* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=07.2018
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==NEFM==
==CNP==


* {{medline-title
* {{medline-title
|title=Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age.
|title=Environmental Enrichment Elicits a Transient Rise of Bioactive C-Type Natriuretic Peptide in Young but Not Aged Rats.
|date=06.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30927131
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30072880
|full-text-url=https://sci-hub.do/10.1007/s10735-019-09820-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060231
}}
}}
==GPC1==
==CNTF==


* {{medline-title
* {{medline-title
|title=Decreased expression of [[GPC1]] in human skin keratinocytes and epidermis during ageing.
|title=Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha.
|date=15.10.2019
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31430521
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30861131
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656591
}}
}}
==NEIL1==
==CNTNAP2==


* {{medline-title
* {{medline-title
|title=[[NEIL1]] stimulates neurogenesis and suppresses neuroinflammation after stress.
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=09.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175982
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526462
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
}}
==SRY==
==COL12A1==


* {{medline-title
* {{medline-title
|title=Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics.
|title=Genetic associations with age of menopause in familial longevity.
|date=26.12.2017
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29371932
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768349
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==SCGN==
==COL13A1==


* {{medline-title
* {{medline-title
|title=Detection and evaluation of DNA methylation markers found at [[SCGN]] and [[KLF14]] loci to estimate human age.
|title=[Alu insertion-deletion polymorphism of [[COL13A1]] and [[LAMA2]] genes: The analysis of association with longevity].
|date=11.2017
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854399
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369589
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011
 
}}
}}
==PYCR1==
==COL1A1==


* {{medline-title
* {{medline-title
|title=A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals [[POSTN]] As a New Element in Proline Metabolic Disorder.
|title=Remodeling process in bone of aged rats in response to resistance training.
|date=12.2018
|date=01.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574417
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32593709
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284769
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2020.118008
}}
}}
==PGLS==
==COL2A1==


* {{medline-title
* {{medline-title
|title=547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates.
|title=Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis.
|date=28.11.2019
|date=08.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779658
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415892
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883628
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821202
}}
}}
==CASP3==
==COL6A1==


* {{medline-title
* {{medline-title
|title=Does cartilage ERα overexpression correlate with osteoarthritic chondrosenescence? Indications from [i]Labisia pumila[/i] OA mitigation.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=09.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31502578
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
==COQ5==


* {{medline-title
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
}}
}}
==CLEC4E==
==COQ6==


* {{medline-title
* {{medline-title
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|date=03.2018
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
}}
}}
==GRID1==
==COQ7==


* {{medline-title
* {{medline-title
|title=Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies.
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|date=03.2020
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2020.02.005
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
}}
}}
==IPMK==
==COQ9==


* {{medline-title
* {{medline-title
|title=Inositol Polyphosphate Multikinase ([i][[IPMK]][/i]), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity.
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|date=08.02.2019
|date=18.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30744060
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
}}
}}
==EIF2B1==
==CPNE1==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence.
|date=06.2018
|date=04.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274830
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://sci-hub.do/10.1111/acel.13276
}}
}}
==WNK1==
==CPT1A==


* {{medline-title
* {{medline-title
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2.
|title=Alteration of fatty acid oxidation by increased [[CPT1A]] on replicative senescence of placenta-derived mesenchymal stem cells.
|date=10.2018
|date=03.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31900237
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941254
}}
}}
==BCL2L11==
==CPT1B==


* {{medline-title
* {{medline-title
|title=miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence.
|title=Effects of carnitine palmitoyltransferases on cancer cellular senescence.
|date=01.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30070697
|full-text-url=https://sci-hub.do/10.1002/jcb.28862
|full-text-url=https://sci-hub.do/10.1002/jcp.27042
}}
}}
==ARID5A==
==CPT2==


* {{medline-title
* {{medline-title
|title=Differentially regulated gene expression in quiescence versus senescence and identification of [[ARID5A]] as a quiescence associated marker.
|title=The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats.
|date=05.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29044508
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32729662
|full-text-url=https://sci-hub.do/10.1002/jcp.26227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511879
}}
}}
==SELENOW==
==CR2==


* {{medline-title
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|date=03.2019
|date=19.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
}}
}}
==PON1==
==CRBN==


* {{medline-title
* {{medline-title
|title=Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview.
|title=Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity.
|date=02.05.2019
|date=24.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31052559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32332723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181703
}}
}}
==PRKDC==
==CREB1==


* {{medline-title
* {{medline-title
|title=DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis.
|title=Arginine Methyltransferase [[PRMT8]] Provides Cellular Stress Tolerance in Aging Motoneurons.
|date=29.08.2019
|date=29.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31464599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716822
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113905
}}
}}
==MAPK11==
==CREB5==


* {{medline-title
* {{medline-title
|title=lncRNA ENSMUST00000134285 Increases [[MAPK11]] Activity, Regulating Aging-Related Myocardial Apoptosis.
|title=Cellular senescence induces replication stress with almost no affect on DNA replication timing.
|date=09.07.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415197
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29963964
|full-text-url=https://sci-hub.do/10.1093/gerona/gly020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133336
}}
}}
==CCNA2==
==CREBBP==


* {{medline-title
* {{medline-title
|title=Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan.
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms.
|date=31.03.2018
|date=22.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29463071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318
}}
}}
==EPHA2==
==CREM==


* {{medline-title
* {{medline-title
|title=Germ-line and somatic [[EPHA2]] coding variants in lens aging and cataract.
|title=Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells.
|date=2017
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29267365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739433
|full-text-url=https://sci-hub.do/10.1111/andr.12665
}}
}}
==DLGAP2==
==CRISPLD2==


* {{medline-title
* {{medline-title
|title=Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=01.09.2020
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32877673
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502175
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
==PIGR==
==CRY2==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=02.2018
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
==STK3==
==CRYAB==


* {{medline-title
* {{medline-title
|title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence.
|title=Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
|date=11.12.2018
|date=28.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389787
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311499
}}
}}
==CARF==
==CSAD==


* {{medline-title
* {{medline-title
|title=Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential.
|title=The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway.
|date=22.05.2020
|date=19.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31112603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131986
|full-text-url=https://sci-hub.do/10.1093/gerona/glz077
|full-text-url=https://sci-hub.do/10.1039/c8fo00740c
}}
}}
==MAP2K3==
==CSF3R==


* {{medline-title
* {{medline-title
|title=Associations of [i][[MAP2K3]][/i] Gene Variants With Superior Memory in SuperAgers.
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|date=2018
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896098
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987172
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
}}
}}
==IRF1==
==CTC1==


* {{medline-title
* {{medline-title
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|title=[[CTC1]]-[[STN1]] coordinates G- and C-strand synthesis to regulate telomere length.
|date=06.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479
}}
}}
==ALK==
==CTNS==


* {{medline-title
* {{medline-title
|title=Catalog of Lung Cancer Gene Mutations Among Chinese Patients.
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading.
|date=2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32850378
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7417348
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869
}}
}}
==RSF1==
==CTSA==


* {{medline-title
* {{medline-title
|title=The SR proteins SF2 and [[RBP1]] regulate triglyceride storage in the fat body of Drosophila.
|title=A [[CTSA]]-based consultation service to advance research on special and underserved populations.
|date=27.08.2019
|date=16.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277943
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33244406
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.151
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681147
}}
}}
==CDC25A==
==CTSL==


* {{medline-title
* {{medline-title
|title=Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage.
|title=Cathepsin L deficiency results in reactive oxygen species (ROS) accumulation and vascular cells activation.
|date=10.10.2020
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29041825
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600899
|full-text-url=https://sci-hub.do/10.1080/10715762.2017.1393665
}}
}}
==P4HA3==
==CTSS==


* {{medline-title
* {{medline-title
|title=Age-associated genes in human mammary gland drive human breast cancer progression.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=15.06.2020
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32539762
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294649
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==SLC15A2==
==CUL3==


* {{medline-title
* {{medline-title
|title=Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing.
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|date=02.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019300
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3413-x
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
}}
==CREB1==
 
* {{medline-title
|title=Arginine Methyltransferase [[PRMT8]] Provides Cellular Stress Tolerance in Aging Motoneurons.
|date=29.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113905
}}
}}
==CUX1==
==CUX1==
Строка 5767: Строка 5719:
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
==APOC3==
==CXCL13==


* {{medline-title
* {{medline-title
|title=Positional Obstructive Sleep Apnea Syndrome in Elderly Patients.
|title=RNA-seq data from C-X-C chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype.
|date=10.02.2020
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32050596
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32642521
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334305
}}
}}
==CBX4==
==CXCL14==


* {{medline-title
* {{medline-title
|title=Maintenance of Nucleolar Homeostasis by [[CBX4]] Alleviates Senescence and Osteoarthritis.
|title=Identification of genes associated with endometrial cell aging.
|date=26.03.2019
|date=01.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30917318
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33258951
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.02.088
|full-text-url=https://sci-hub.do/10.1093/molehr/gaaa078
}}
}}
==PLK1==
==CXCL16==


* {{medline-title
* {{medline-title
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|title=[[CXCR6]] Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and [[CD4]]  T-Cell-Dependent Control of Senescence.
|date=09.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710528
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
|full-text-url=https://sci-hub.do/10.1053/j.gastro.2019.01.247
}}
}}
==RUNX3==
==CXCL17==


* {{medline-title
* {{medline-title
|title=circLARP4 induces cellular senescence through regulating miR-761/[[RUNX3]]/p53/p21 signaling in hepatocellular carcinoma.
|title=[Age-related aspects of the involvement of heat shock proteins in the pathogenesis of osteoarthritis].
|date=02.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30520539
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849876
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361555
 
}}
}}
==CCND3==
==CXCR1==


* {{medline-title
* {{medline-title
|title=The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells.
|title=Harmful neutrophil subsets in patients with ischemic stroke: Association with disease severity.
|date=29.07.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32727592
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31355307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392710
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624098
}}
}}
==LDLR==
==CXCR5==


* {{medline-title
* {{medline-title
|title=Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice.
|title=Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses.
|date=08.2018
|date=17.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29903737
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28817118
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092113
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596542
}}
}}
==SUN2==
==CXCR6==


* {{medline-title
* {{medline-title
|title=Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging.
|title=[[CXCR6]] Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and [[CD4]]  T-Cell-Dependent Control of Senescence.
|date=26.02.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397528
|full-text-url=https://sci-hub.do/10.1053/j.gastro.2019.01.247
}}
}}
==PPA2==
==CYB5A==


* {{medline-title
* {{medline-title
|title=Characterization of long living yeast deletion mutants that lack mitochondrial metabolism genes DSS1, [[PPA2]] and AFG3.
|title=11-Oxygenated C19 Steroids Do Not Decline With Age in Women.
|date=20.07.2019
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31082499
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753518
|full-text-url=https://sci-hub.do/10.1016/j.gene.2019.05.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525564
}}
}}
==TXNDC5==
==CYB5R3==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Overexpression of [[CYB5R3]] and [[NQO1]], two NAD  -producing enzymes, mimics aspects of caloric restriction.
|date=10.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052403
}}
}}
==MAP4K3==
==CYP11B1==


* {{medline-title
* {{medline-title
|title=[[MAP4K3]]/GLK in autoimmune disease, cancer and aging.
|title=Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼.
|date=22.10.2019
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31640697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806545
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105764
}}
}}
==NKX2-5==
==CYP11B2==


* {{medline-title
* {{medline-title
|title=Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart.
|title=Expression of aldosterone synthase [[CYP11B2]] was inversely correlated with longevity.
|date=07.01.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30663680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30974191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207148
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786771
}}
}}
==TJP1==
==CYP17A1==


* {{medline-title
* {{medline-title
|title=Morphological and immunohistochemical characteristics of the equine corneal epithelium.
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio).
|date=11.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900071
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128
}}
}}
==MAS1==
==CYP19A1==


* {{medline-title
* {{medline-title
|title=AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation.
|title=Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model.
|date=17.04.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667931
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940107
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.016
}}
}}
==IL4==
==CYP1B1==


* {{medline-title
* {{medline-title
|title=Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia.
|title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts.
|date=01.01.2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122767
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756472
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3
}}
}}
==TRIM27==
==CYP24A1==


* {{medline-title
* {{medline-title
|title=[[TRIM27]] Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination.
|title=Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism.
|date=04.12.2020
|date=22.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33251042
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666371
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823
}}
}}
==FBXO46==
==CYP26A1==


* {{medline-title
* {{medline-title
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|date=19.10.2018
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
}}
}}
==MATN3==
==CYP26B1==


* {{medline-title
* {{medline-title
|title=Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis.
|title=Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia.
|date=19.01.2020
|date=20.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31963938
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32385093
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013758
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244205
}}
}}
==TRIB3==
==CYP2C9==


* {{medline-title
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
|date=2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442
}}
}}
==BCL11B==
==CYP2R1==


* {{medline-title
* {{medline-title
|title=Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells.
|title=Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance.
|date=05.2018
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29360511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955863
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693043
}}
}}
==TRPC1==
==CYP3A5==


* {{medline-title
* {{medline-title
|title=Ca  entry via [[TRPC1]] is essential for cellular differentiation and modulates secretion via the SNARE complex.
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia.
|date=01.07.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182642
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442
}}
}}
==DEPTOR==
==DAP==


* {{medline-title
* {{medline-title
|title=[[DEPTOR]] at the Nexus of Cancer, Metabolism, and Immunity.
|title=Examining changes in the equity of physician distribution in Japan: a specialty-specific longitudinal study.
|date=01.07.2018
|date=08.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29317415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781009
}}
}}
==SYNJ2==
==DAPK2==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=25.07.2018
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==RNF144A==
==DAXX==


* {{medline-title
* {{medline-title
|title=Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease.
|title=[[ATRX]]-[[DAXX]] Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains.
|date=09.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31280115
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31361513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732230
|full-text-url=https://sci-hub.do/10.1089/dna.2019.4752
}}
}}
==PKD1==
==DAZL==


* {{medline-title
* {{medline-title
|title=The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response.
|title=[[DAZL]] Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.
|date=16.03.2018
|date=30.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29420297
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380414
|full-text-url=https://sci-hub.do/10.1242/jcs.207217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878787
}}
}}
==PDHB==
==DBH==


* {{medline-title
* {{medline-title
|title=Neuron-specific knockdown of Drosophila [[PDHB]] induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting.
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children.
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501567
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.02.035
}}
==NLRP1==
 
* {{medline-title
|title=NADPH oxidase 2-mediated [[NLRP1]] inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro.
|date=04.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677569
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2019.01.025
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711
}}
}}
==GYS2==
==DBT==


* {{medline-title
* {{medline-title
|title=In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers.
|title=Diurnal rhythms of heart and respiratory rates in donkeys of different age groups during the cold-dry and hot-dry seasons in a tropical savannah.
|date=04.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986936
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187687
|full-text-url=https://sci-hub.do/10.1111/jpn.12831
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125241
}}
}}
==MS4A1==
==DCAF17==


* {{medline-title
* {{medline-title
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|title=Deletion of [[DDB1]]- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice.
|date=19.01.2019
|date=15.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907856
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003934
}}
}}
==LPAR3==
==DCLRE1C==


* {{medline-title
* {{medline-title
|title=Upregulated microRNA-15b alleviates ovarian cancer through inhitbition of the PI3K/Akt pathway by targeting [[LPAR3]].
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|date=12.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140597
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|full-text-url=https://sci-hub.do/10.1002/jcp.28799
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
}}
}}
==DYRK1A==
==DCTN2==


* {{medline-title
* {{medline-title
|title=Altered age-linked regulation of plasma [[DYRK1A]] in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load.
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|date=2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32642550
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331462
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
}}
}}
==HSD17B14==
==DCTN3==


* {{medline-title
* {{medline-title
|title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts.
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|date=04.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
}}
}}
==GNPAT==
==DCTN6==


* {{medline-title
* {{medline-title
|title=Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|date=05.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30128650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1307-2
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
}}
}}
==SMAD1==
==DDI2==


* {{medline-title
* {{medline-title
|title=TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands.
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
|date=26.11.2019
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779094
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928867
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498
}}
}}
==PDE10A==
==DDIT3==


* {{medline-title
* {{medline-title
|title=Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain.
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=01.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175000
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
}}
==ATXN1==
==DDR1==


* {{medline-title
* {{medline-title
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|title=Age-related modifications of type I collagen impair [[DDR1]]-induced apoptosis in non-invasive breast carcinoma cells.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363044
}}
}}
==KCTD12==
==DDR2==


* {{medline-title
* {{medline-title
|title=The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort.
|title=Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging.
|date=2020
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32970748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514036
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833185
}}
}}
==PHB==
==DEPDC5==


* {{medline-title
* {{medline-title
|title=Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|date=02.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30674441
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412871
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
}}
}}
==CYP26B1==
==DEPTOR==


* {{medline-title
* {{medline-title
|title=Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia.
|title=[[DEPTOR]] at the Nexus of Cancer, Metabolism, and Immunity.
|date=20.05.2020
|date=01.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32385093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897294
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7244205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335100
}}
}}
==ATXN3==
==DES==


* {{medline-title
* {{medline-title
|title=Rescue of [[ATXN3]] neuronal toxicity in [i]Caenorhabditis[/i][i]elegans[/i] by chemical modification of endoplasmic reticulum stress.
|title=Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis.
|date=19.12.2017
|date=20.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29061563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29558926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769603
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859529
}}
}}
==PCMTD1==
==DGAT1==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPα-p300/[[DGAT1]] pathway.
|date=12.2017
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024407
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771394
}}
}}
==GCAT==
==DGAT2==


* {{medline-title
* {{medline-title
|title=Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=03.04.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29551589
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2018.02.004
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
==KDM4A==
==DGCR8==


* {{medline-title
* {{medline-title
|title=Structure-Based Discovery of a Selective [[KDM5A]] Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines.
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif.
|date=15.01.2019
|date=29.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30650517
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004
}}
}}
==TBC1D1==
==DHRS2==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Acute [[HSF1]] depletion induces cellular senescence through the [[MDM2]]-p53-p21 pathway in human diploid fibroblasts.
|date=02.2019
|date=08.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632240
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://sci-hub.do/10.1242/jcs.210724
}}
}}
==FER==
==DIAPH1==


* {{medline-title
* {{medline-title
|title=Tracking the recognition of static and dynamic facial expressions of emotion across the life span.
|title=Diaphanous 1 ([[DIAPH1]]) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease.
|date=04.09.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30208425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966194
|full-text-url=https://sci-hub.do/10.1167/18.9.5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082178
}}
}}
==MAP3K5==
==DIP2A==


* {{medline-title
* {{medline-title
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|title=Blocking the [[FSTL1]]-[[DIP2A]] Axis Improves Anti-tumor Immunity.
|date=08.10.2018
|date=14.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30110636
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.07.043
}}
}}
==KLB==
==DKK2==


* {{medline-title
* {{medline-title
|title=Infants Uniquely Express High Levels of [[RBM3]] and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain.
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women.
|date=2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399610
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311128
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448
}}
}}
==CHEK2==
==DLAT==


* {{medline-title
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=20.06.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==RBM3==
==DLC1==


* {{medline-title
* {{medline-title
|title=Infants Uniquely Express High Levels of [[RBM3]] and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain.
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells.
|date=2018
|date=15.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399610
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311128
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031
}}
}}
==TP53INP1==
==DLGAP2==


* {{medline-title
* {{medline-title
|title=[[TP53INP1]] deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling.
|title=Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
|date=02.01.2019
|date=01.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559202
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32877673
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320535
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502175
}}
}}
==FOXD1==
==DLL1==


* {{medline-title
* {{medline-title
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|title=MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting [[DLL1]] and Regulating PI3K/AKT Pathway.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048987
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
|full-text-url=https://sci-hub.do/10.1159/000492090
}}
}}
==ALDH3A1==
==DLL4==


* {{medline-title
* {{medline-title
|title=Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs).
|title=Dynamic regulation of [[NOTCH1]] activation and Notch ligand expression in human thymus development.
|date=13.02.2019
|date=13.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30042180
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382415
|full-text-url=https://sci-hub.do/10.1242/dev.165597
}}
}}
==GRIN2B==
==DMP1==


* {{medline-title
* {{medline-title
|title=Medial temporal lobe atrophy relates more strongly to sleep-wake rhythm fragmentation than to age or any other known risk.
|title=Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice.
|date=04.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29864525
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978155
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2018.05.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029870
}}
}}
==MCM4==
==DMPK==


* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans.
|date=27.07.2019
|date=19.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30878478
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://sci-hub.do/10.1016/j.jmb.2019.03.003
}}
}}
==ZNF207==
==DNAJB9==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=[[DNAJB9]] Inhibits p53-Dependent Oncogene-Induced Senescence and Induces Cell Transformation.
|date=02.2018
|date=30.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32264658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191047
}}
}}
==MPST==
==DNM1==


* {{medline-title
* {{medline-title
|title=Methionine restriction leads to hyperhomocysteinemia and alters hepatic H S production capacity in Fischer-344 rats.
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30367932
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.10.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
}}
}}
==TPH1==
==DNM2==


* {{medline-title
* {{medline-title
|title=[i]Lactobacillus plantarum[/i] DR7 improved brain health in aging rats via the serotonin, inflammatory and apoptosis pathways.
|title=Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy.
|date=02.12.2020
|date=19.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33245015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451843
|full-text-url=https://sci-hub.do/10.3920/BM2019.0200
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243013
}}
}}
==NRXN3==
==DNMT3L==


* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Transient [[DNMT3L]] Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast.
|date=07.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32195249
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064442
}}
}}
==SDC3==
==DOCK11==


* {{medline-title
* {{medline-title
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|title=[Immunosenescence: The Forefront of Infection and Trophic Control].
|date=01.10.2017
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115558
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00193-3
}}
}}
==HLA-DQB1==
==DOT1L==


* {{medline-title
* {{medline-title
|title=Identification of new genetic variants of [[HLA-DQB1]] associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population.
|title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction.
|date=10.11.2017
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129831
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723689
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018
}}
}}
==APLP2==
==DPP6==


* {{medline-title
* {{medline-title
|title=Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex.
|title=A novel structure associated with aging is augmented in the [[DPP6]]-KO mouse brain.
|date=06.2019
|date=23.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30362021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33225987
|full-text-url=https://sci-hub.do/10.1007/s11064-018-2669-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682109
}}
}}
==EZR==
==DPT==


* {{medline-title
* {{medline-title
|title=Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model.
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography.
|date=03.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29245059
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801041
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0
}}
}}
==RAD51C==
==DPYSL2==


* {{medline-title
* {{medline-title
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|title=Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease.
|date=06.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31733664
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939615
}}
}}
==GPBAR1==
==DRAM1==


* {{medline-title
* {{medline-title
|title=Activation of the bile acid receptor [[GPBAR1]] (TGR5) ameliorates interleukin-1β (IL-1β)- induced chondrocytes senescence.
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
|date=10.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.06.154
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896
}}
}}
==MS4A6A==
==DRAM2==
 
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
==UCN3==
 
* {{medline-title
|title=Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise-induced threshold shift.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31270820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852351
}}
==CTSS==


* {{medline-title
* {{medline-title
Строка 6295: Строка 6223:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==MECOM==
==DRD1==


* {{medline-title
* {{medline-title
|title=Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.
|title=Impact of dopamine-related genetic variants on physical activity in old age - a cohort study.
|date=11.2018
|date=24.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32448293
|full-text-url=https://sci-hub.do/10.1111/jgh.14149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245799
}}
}}
==CA12==
==DRD4==


* {{medline-title
* {{medline-title
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children.
|date=26.06.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711
}}
}}
==SDHB==
==DROSHA==


* {{medline-title
* {{medline-title
|title=Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study.
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability.
|date=12.02.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32059608
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072
}}
}}
==DUSP1==
==DSC1==


* {{medline-title
* {{medline-title
|title=miR-1468-3p Promotes Aging-Related Cardiac Fibrosis.
|title=HDLs and the pathogenesis of atherosclerosis.
|date=05.06.2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32348937
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29561322
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191129
|full-text-url=https://sci-hub.do/10.1097/HCO.0000000000000508
}}
}}
==EVL==
==DSCAM==


* {{medline-title
* {{medline-title
|title=Health Years in Total: A New Health Objective Function for Cost-Effectiveness Analysis.
|title=Age- and speed-dependent modulation of gaits in [[DSCAM]]  mutant mice.
|date=01.2020
|date=01.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31952678
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29093169
|full-text-url=https://sci-hub.do/10.1016/j.jval.2019.10.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867377
}}
}}
==PRKN==
==DSE==


* {{medline-title
* {{medline-title
|title=[[PRKN]]-regulated mitophagy and cellular senescence during COPD pathogenesis.
|title=Impact of Intensive Lifestyle Intervention on Disability-Free Life Expectancy: The Look AHEAD Study.
|date=03.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30290714
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545462
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911793
}}
}}
==BNC1==
==DSPP==


* {{medline-title
* {{medline-title
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|title=Effects of [i]p[/i]-Cresol on Senescence, Survival, Inflammation, and Odontoblast Differentiation in Canine Dental Pulp Stem Cells.
|date=22.01.2020
|date=21.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32967298
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555360
}}
}}
==SMN1==
==DTL==


* {{medline-title
* {{medline-title
|title=Changing respiratory expectations with the new disease trajectory of nusinersen treated spinal muscular atrophy [SMA] type 1.
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|date=09.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|full-text-url=https://sci-hub.do/10.1016/j.prrv.2018.07.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
}}
}}
==PDE9A==
==DTNBP1==


* {{medline-title
* {{medline-title
|title=Identification of new [[PDE9A]] isoforms and how their expression and subcellular compartmentalization in the brain change across the life span.
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|date=05.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29505961
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
}}
}}
==EXD2==
==DUSP1==


* {{medline-title
* {{medline-title
|title=[[EXD2]] governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation.
|title=miR-1468-3p Promotes Aging-Related Cardiac Fibrosis.
|date=02.2018
|date=05.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29335528
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32348937
|full-text-url=https://sci-hub.do/10.1038/s41556-017-0016-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191129
}}
}}
==GOT1==
==DUSP2==


* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Aging Increases Hippocampal [[DUSP2]] by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism.
|date=07.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31293510
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603139
}}
}}
==OGA==
==DUSP8==


* {{medline-title
* {{medline-title
|title=NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase.
|title=MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats.
|date=19.11.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31747588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31400088
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.10.053
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826124
}}
}}
==PRRX1==
==DUT==


* {{medline-title
* {{medline-title
|title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis.
|title=Simultaneous liquefaction, saccharification, and fermentation of L-lactic acid using aging paddy rice with hull by an isolated thermotolerant Enterococcus faecalis [[DUT]]1805.
|date=12.2018
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32388689
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862
|full-text-url=https://sci-hub.do/10.1007/s00449-020-02364-y
}}
}}
==TINF2==
==DYNC2H1==


* {{medline-title
* {{medline-title
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|title=Role for intraflagellar transport in building a functional transition zone.
|date=04.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429209
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280794
}}
}}
==USP15==
==DYRK1A==


* {{medline-title
* {{medline-title
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i].
|title=Altered age-linked regulation of plasma [[DYRK1A]] in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load.
|date=29.05.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32642550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331462
}}
}}
==LGALS3==
==E2F3==


* {{medline-title
* {{medline-title
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|title=Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution.
|date=2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730547
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
|full-text-url=https://sci-hub.do/10.1016/j.molimm.2018.04.010
}}
}}
==ATP6V0C==
==ECM1==


* {{medline-title
* {{medline-title
|title=A pH probe inhibits senescence in mesenchymal stem cells.
|title=Novel role of extracellular matrix protein 1 ([[ECM1]]) in cardiac aging and myocardial infarction.
|date=07.12.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30526663
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383988
}}
}}
==ARID1B==
==ECRG4==


* {{medline-title
* {{medline-title
|title=A 69-year-old woman with Coffin-Siris syndrome.
|title=[[ECRG4]]: a new potential target in precision medicine.
|date=08.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055038
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003403
|full-text-url=https://sci-hub.do/10.1002/ajmg.a.38844
|full-text-url=https://sci-hub.do/10.1007/s11684-018-0637-9
}}
}}
==FRG1==
==ECSIT==


* {{medline-title
* {{medline-title
|title=Intergenerational response of steroidogenesis-related genes to maternal malnutrition.
|title=Longevity-related molecular pathways are subject to midlife "switch" in humans.
|date=10.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789120
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168962
|full-text-url=https://sci-hub.do/10.1017/S2040174419000060
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612641
}}
}}
==PTPRD==
==EDEM1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=15.11.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
==ADRM1==
==EDF1==


* {{medline-title
* {{medline-title
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
|title=Silencing of FOREVER YOUNG FLOWER Like Genes from Phalaenopsis Orchids Promotes Flower Senescence and Abscission.
|date=01.08.2018
|date=25.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33237274
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498
|full-text-url=https://sci-hub.do/10.1093/pcp/pcaa145
}}
}}
==ESPL1==
==EDN1==


* {{medline-title
* {{medline-title
|title=Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants.
|title=Dexamethasone downregulates [[SIRT1]] and [[IL6]] and upregulates [[EDN1]] genes in stem cells derived from gingivae via the AGE/RAGE pathway.
|date=09.2020
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32574725
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29302812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461696
|full-text-url=https://sci-hub.do/10.1007/s10529-017-2493-0
}}
}}
==PGK2==
==EED==


* {{medline-title
* {{medline-title
|title=Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
|title=Economic evaluations of eHealth technologies: A systematic review.
|date=01.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31472347
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897921
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2019.124650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999277
}}
}}
==IL18==
==EFEMP1==


* {{medline-title
* {{medline-title
|title=Aging and the Inflammasomes.
|title=A novel age-related venous amyloidosis derived from [[EGF]]-containing fibulin-like extracellular matrix protein 1.
|date=2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30536177
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30565683
|full-text-url=https://sci-hub.do/10.1007/978-3-319-89390-7_13
|full-text-url=https://sci-hub.do/10.1002/path.5203
}}
}}
==PDE5A==
==EHF==


* {{medline-title
* {{medline-title
|title=Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass.
|title=Extended high frequency hearing and speech perception implications in adults and children.
|date=23.06.2020
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32513693
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32111404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321982
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431381
}}
}}
==SIX3==
==EID3==


* {{medline-title
* {{medline-title
|title=CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type.
|title=Upregulation of [[EID3]] sensitizes breast cancer cells to ionizing radiation-induced cellular senescence.
|date=30.11.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30114644
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265269
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.08.022
}}
}}
==RAD51B==
==EIF2B1==


* {{medline-title
* {{medline-title
|title=Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human [[RAD52]] gene in a cardiovascular cohort.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=10.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024686
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.10.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==MLH3==
==EIF2B2==


* {{medline-title
* {{medline-title
|title=Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=19.10.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942922
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679441
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==KCNB1==
==EIF2B3==


* {{medline-title
* {{medline-title
|title=Oxidation of [[KCNB1]] potassium channels in the murine brain during aging is associated with cognitive impairment.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=14.05.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922570
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471606
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==AHCY==
==EIF2B4==


* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=11.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==WDR73==
==EIF2B5==


* {{medline-title
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=11.04.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==INHBE==
==EIF4E==


* {{medline-title
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|title=Transcriptomic evidence that insulin signalling pathway regulates the ageing of subterranean termite castes.
|date=18.03.2019
|date=18.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32424344
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235038
}}
}}
==FOXN1==
==ELANE==


* {{medline-title
* {{medline-title
|title=Thymic rejuvenation via [[FOXN1]]-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation.
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|date=17.09.2020
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32790650
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526556
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
}}
}}
==TRIP13==
==ELF3==


* {{medline-title
* {{medline-title
|title=BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.
|title=High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in [i]Arabidopsis[/i].
|date=02.01.2020
|date=31.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31738183
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32732458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934189
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398796
}}
}}
==IL17RA==
==ELL==


* {{medline-title
* {{medline-title
|title=Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon.
|title=Exceptional Longevity and Polygenic Risk for Cardiovascular Health.
|date=2017
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039977
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30889929
|full-text-url=https://sci-hub.do/10.1080/07420528.2017.1361436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471529
}}
}}
==MRPS5==
==ELOVL6==


* {{medline-title
* {{medline-title
|title=Mutant [[MRPS5]] affects mitoribosomal accuracy and confers stress-related behavioral alterations.
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|date=11.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30237157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216279
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
}}
}}
==TEF==
==EML6==


* {{medline-title
* {{medline-title
|title=Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response.
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|date=10.2020
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32189112
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09869-9
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
}}
}}
==HPD==
==ENC1==


* {{medline-title
* {{medline-title
|title=Protein-Amino Acid Metabolism Disarrangements: The Hidden Enemy of Chronic Age-Related Conditions.
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=22.03.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29565819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946176
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
}}
==RXRA==
==ENO1==


* {{medline-title
* {{medline-title
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling.
|title=Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells.
|date=12.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32355541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191177
}}
}}
==RPS19BP1==
==ENTPD7==


* {{medline-title
* {{medline-title
|title=Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence.
|title=Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 ([[ENTPD7]]).
|date=10.2020
|date=23.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659678
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31443651
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2020.153275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708200
}}
}}
==UQCRC2==
==EPG5==


* {{medline-title
* {{medline-title
|title=Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10).
|title=Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom.
|date=06.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486404
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882010
}}
}}
==ITK==
==EPHA1==


* {{medline-title
* {{medline-title
|title=Does Tetralogy of Fallot affect brain aging? A proof-of-concept study.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=2018
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103512
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
==NSF==
==EPHA2==


* {{medline-title
* {{medline-title
|title=Effects of air pollution on children from a socioecological perspective.
|title=Germ-line and somatic [[EPHA2]] coding variants in lens aging and cataract.
|date=15.11.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31727016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29267365
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857293
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739433
}}
}}
==COL12A1==
==ERAP1==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=10.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==SELENOT==
==ERBB4==


* {{medline-title
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|title=Overexpression of [[ERBB4]] rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways.
|date=03.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30566395
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
|full-text-url=https://sci-hub.do/10.1096/fj.201801690R
}}
}}
==FA2H==
==ERCC2==


* {{medline-title
* {{medline-title
|title=C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production.
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30184537
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
}}
==RACK1==
==ERCC5==


* {{medline-title
* {{medline-title
|title=Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging.
|title=Identification of a [[ERCC5]] c.2333T>C (L778P) Variant in Two Tunisian Siblings With Mild Xeroderma Pigmentosum Phenotype.
|date=05.11.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31636180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30838033
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383105
}}
}}
==FAHD1==
==ERCC6==


* {{medline-title
* {{medline-title
|title=Oxaloacetate decarboxylase [[FAH]]D1 - a new regulator of mitochondrial function and senescence.
|title=Two Cockayne Syndrome patients with a novel splice site mutation - clinical and metabolic analyses.
|date=01.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055189
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29944916
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.07.007
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.001
}}
}}
==MST1==
==ERCC8==


* {{medline-title
* {{medline-title
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.
|date=25.06.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141
}}
}}
==NTHL1==
==ESPL1==


* {{medline-title
* {{medline-title
|title=Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals.
|title=Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants.
|date=04.2020
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970600
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32574725
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205949
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461696
}}
}}
==KCNQ4==
==ESR1==


* {{medline-title
* {{medline-title
|title=Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss.
|title=Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement.
|date=2020
|date=05.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32327991
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160671
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788639
}}
}}
==ITGB4==
==ESRG==


* {{medline-title
* {{medline-title
|title=[[ITGB4]] deficiency induces senescence of airway epithelial cells through p53 activation.
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|date=03.2019
|date=10.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30636108
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|full-text-url=https://sci-hub.do/10.1111/febs.14749
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
}}
}}
==MRTFA==
==ETV5==


* {{medline-title
* {{medline-title
|title=Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse.
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
|date=01.02.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30422822
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355303
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
}}
}}
==KLF6==
==ETV6==


* {{medline-title
* {{medline-title
|title=Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence.
|title=[[FOXO1]] and [[ETV6]] genes may represent novel regulators of splicing factor expression in cellular senescence.
|date=2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31824948
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882731
|full-text-url=https://sci-hub.do/10.1096/fj.201801154R
}}
}}
==FABP1==
==EVL==


* {{medline-title
* {{medline-title
|title=Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken.
|title=Health Years in Total: A New Health Objective Function for Cost-Effectiveness Analysis.
|date=01.09.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065718
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31952678
|full-text-url=https://sci-hub.do/10.3382/ps/pez249
|full-text-url=https://sci-hub.do/10.1016/j.jval.2019.10.014
}}
}}
==CHIA==
==EWSR1==


* {{medline-title
* {{medline-title
|title=Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets.
|title=[[EWSR1]], a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways.
|date=26.11.2018
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30486328
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30481590
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316572
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527469
}}
}}
==SGSH==
==EXD2==


* {{medline-title
* {{medline-title
|title=MPS-IIIA mice acquire autistic behaviours with age.
|title=[[EXD2]] governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation.
|date=07.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520737
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29335528
|full-text-url=https://sci-hub.do/10.1007/s10545-018-0160-9
|full-text-url=https://sci-hub.do/10.1038/s41556-017-0016-9
}}
}}
==MX1==
==EXO1==


* {{medline-title
* {{medline-title
|title=Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection.
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|date=10.11.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878083
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230210
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
}}
}}
==BCAS1==
==EXOC7==


* {{medline-title
* {{medline-title
|title=Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs).
|title=[[PTBP1]]-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.
|date=13.02.2019
|date=09.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30760648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990503
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048363
}}
}}
==KCNQ2==
==EZR==


* {{medline-title
* {{medline-title
|title=Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for [[GNG4]] and [[KCNQ2]] Genes.
|title=Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model.
|date=05.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338302
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29245059
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801041
}}
}}
==CPT1A==
==F10==


* {{medline-title
* {{medline-title
|title=Alteration of fatty acid oxidation by increased [[CPT1A]] on replicative senescence of placenta-derived mesenchymal stem cells.
|title=Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-[[F10]] cells by inducing senescence.
|date=03.01.2020
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31900237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941254
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.06.008
}}
}}
==ADNP2==
==F12==


* {{medline-title
* {{medline-title
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|title=Multigenerational effects of carbendazim in Daphnia magna: From a subcellular to a population level.
|date=06.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30508263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
|full-text-url=https://sci-hub.do/10.1002/etc.4307
}}
}}
==SMARCD1==
==FA2H==


* {{medline-title
* {{medline-title
|title=Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells.
|title=C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30155609
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30184537
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428043
}}
}}
==ARNTL2==
==FABP1==


* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken.
|date=21.11.2018
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065718
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://sci-hub.do/10.3382/ps/pez249
}}
}}
==SYP==
==FADD==


* {{medline-title
* {{medline-title
|title=The neuropeptide-12 improves recognition memory and neuronal plasticity of the limbic system in old rats.
|title=Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal [[FADD]].
|date=08.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29740871
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30138765
|full-text-url=https://sci-hub.do/10.1002/syn.22036
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2018.07.014
}}
}}
==AXL==
==FADS1==


* {{medline-title
* {{medline-title
|title=Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells.
|title=Aging and [[FADS1]] polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U- C]linoleic acid.
|date=01.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31310445
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31492428
|full-text-url=https://sci-hub.do/10.1111/pcmr.12811
|full-text-url=https://sci-hub.do/10.1016/j.plefa.2019.07.003
}}
}}
==MSH3==
==FAH==


* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=Oxaloacetate decarboxylase [[FAH]]D1 - a new regulator of mitochondrial function and senescence.
|date=25.02.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055189
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.07.007
}}
}}
==HAP1==
==FAHD1==


* {{medline-title
* {{medline-title
|title=The longevity SNP rs2802292 uncovered: [[HSF1]] activates stress-dependent expression of [[FOXO3]] through an intronic enhancer.
|title=Oxaloacetate decarboxylase [[FAH]]D1 - a new regulator of mitochondrial function and senescence.
|date=20.06.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733381
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055189
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009585
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.07.007
}}
}}
==EML6==
==FAM13A==


* {{medline-title
* {{medline-title
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease.
|date=07.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171
}}
}}
==NT5E==
==FANCC==


* {{medline-title
* {{medline-title
|title=The [[NT5E]] gene variant strongly affects the degradation rate of inosine 5'-monophosphate under postmortem conditions in Japanese Black beef.
|title=Fanconi Anemia complementation group C protein in metabolic disorders.
|date=12.2019
|date=21.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31401370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29930218
|full-text-url=https://sci-hub.do/10.1016/j.meatsci.2019.107893
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046246
}}
}}
==PDF==
==FAR2==


* {{medline-title
* {{medline-title
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models.
|title=[[FAR2]] is associated with kidney disease in mice and humans.
|date=28.05.2019
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29652635
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139637
}}
}}
==PTK2B==
==FASN==


* {{medline-title
* {{medline-title
|title=Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=11.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297968
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354244
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
==OXR1==
==FBN2==


* {{medline-title
* {{medline-title
|title=Oxidation resistance 1 is a novel senolytic target.
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging.
|date=08.2018
|date=26.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29766639
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052462
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848
}}
}}
==GLI1==
==FBXO31==


* {{medline-title
* {{medline-title
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|date=02.2019
|date=19.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
}}
}}
==SP7==
==FBXO46==


* {{medline-title
* {{medline-title
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|date=06.2019
|date=19.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
}}
}}
==SFRP5==
==FCER1G==


* {{medline-title
* {{medline-title
|title=[[SFRP5]] serves a beneficial role in arterial aging by inhibiting the proliferation, migration and inflammation of smooth muscle cells.
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|date=11.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30221661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|full-text-url=https://sci-hub.do/10.3892/mmr.2018.9467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
}}
}}
==PPARGC1A==
==FCGR2A==


* {{medline-title
* {{medline-title
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|title=Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells.
|date=08.07.2019
|date=03.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377747
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710049
}}
}}
==HMGCS1==
==FDPS==


* {{medline-title
* {{medline-title
|title=The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
|date=15.10.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.08.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922
}}
}}
==COQ6==
==FER==


* {{medline-title
* {{medline-title
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|title=Tracking the recognition of static and dynamic facial expressions of emotion across the life span.
|date=18.09.2018
|date=04.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30208425
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
|full-text-url=https://sci-hub.do/10.1167/18.9.5
}}
}}
==IGHD==
==FER1L6==


* {{medline-title
* {{medline-title
|title=Growth Hormone Deficiency: Health and Longevity.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=01.04.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416709
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==TEP1==
==FEZ1==


* {{medline-title
* {{medline-title
|title=[Influence of Age on the Susceptibility of Anopheles stephensi to Plasmodium berghei Infection].
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|date=12.2016
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30141604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
}}
}}
==MAF==
==FGF6==


* {{medline-title
* {{medline-title
|title=Biocatalytic Degradation Efficiency of Postconsumer Polyethylene Terephthalate Packaging Determined by Their Polymer Microstructures.
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|date=17.07.2019
|date=06.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31380212
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
}}
}}
==NDUFS8==
==FGFR2==


* {{medline-title
* {{medline-title
|title=Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity.
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|date=01.10.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32773682
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494633
|full-text-url=https://sci-hub.do/10.1002/path.5314
}}
}}
==RPL36==
==FKBP5==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Epigenetic upregulation of [[FKBP5]] by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk.
|date=2019
|date=04.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113877
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561294
}}
}}
==CACNA1B==
==FLT3==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|date=10.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
}}
}}
==CBX3==
==FMO3==


* {{medline-title
* {{medline-title
|title=Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development.
|title=Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver.
|date=24.09.2020
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32979540
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28819071
|full-text-url=https://sci-hub.do/10.1016/j.bone.2020.115659
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697103
}}
}}
==MEOX2==
==FMR1==


* {{medline-title
* {{medline-title
|title=Reduced expression of microRNA-130a promotes endothelial cell senescence and age-dependent impairment of neovascularization.
|title=Static and dynamic postural control deficits in aging fragile X mental retardation 1 ([[FMR1]]) gene premutation carriers.
|date=26.05.2020
|date=21.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32457253
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30665341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341725
}}
}}
==CLEC3B==
==FNTA==


* {{medline-title
* {{medline-title
|title=[[CLEC3B]] p.S106G Mutant in a Caucasian Population of Successful Neurological Aging.
|title=The Hip Morphology Changes with Ageing in Asian Population.
|date=16.09.2020
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570938
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30363710
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180959
}}
}}
==ECSIT==
==FOSL2==


* {{medline-title
* {{medline-title
|title=Longevity-related molecular pathways are subject to midlife "switch" in humans.
|title=LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.
|date=08.2019
|date=03.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168962
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32149459
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612641
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132339
}}
}}
==KRT15==
==FOXC1==


* {{medline-title
* {{medline-title
|title=Extracellular proteoglycan decorin maintains human hair follicle stem cells.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=12.2018
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320452
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1111/1346-8138.14678
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
==SARM1==
==FOXD1==


* {{medline-title
* {{medline-title
|title=Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.
|title=MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to [[FOXD1]].
|date=03.10.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640801
|full-text-url=https://sci-hub.do/10.1007/s00432-018-2745-y
}}
}}
==HLA-DPA1==
==FOXL2==


* {{medline-title
* {{medline-title
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|title=Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor.
|date=09.2019
|date=09.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29523193
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845161
}}
}}
==GSTT1==
==FOXN1==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Thymic rejuvenation via [[FOXN1]]-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation.
|date=12.2018
|date=17.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32790650
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526556
}}
}}
==IKBKB==
==FOXP2==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.
|date=02.2019
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247
}}
}}
==MAPK13==
==FOXP4==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.
|date=15.11.2018
|date=06.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247
}}
}}
==E2F3==
==FRG1==


* {{medline-title
* {{medline-title
|title=Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution.
|title=Intergenerational response of steroidogenesis-related genes to maternal malnutrition.
|date=07.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29730547
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789120
|full-text-url=https://sci-hub.do/10.1016/j.molimm.2018.04.010
|full-text-url=https://sci-hub.do/10.1017/S2040174419000060
}}
}}
==PAX5==
==FRG2==


* {{medline-title
* {{medline-title
|title=Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low [[PAX5]].
|title=Intergenerational response of steroidogenesis-related genes to maternal malnutrition.
|date=08.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29425852
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789120
|full-text-url=https://sci-hub.do/10.1016/j.clim.2018.02.003
|full-text-url=https://sci-hub.do/10.1017/S2040174419000060
}}
}}
==BHLHE40==
==FSTL1==


* {{medline-title
* {{medline-title
|title=Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1.
|title=Blocking the [[FSTL1]]-[[DIP2A]] Axis Improves Anti-tumor Immunity.
|date=07.2020
|date=14.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32360904
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30110636
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105689
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.07.043
}}
}}
==TLR3==
==FZD4==


* {{medline-title
* {{medline-title
|title=Repetitive [[TLR3]] activation in the lung induces skeletal muscle adaptations and cachexia.
|title=MiR-1292 Targets [[FZD4]] to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway.
|date=06.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452288
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911410
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284756
}}
}}
==PPFIA1==
==G6PC==


* {{medline-title
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|title=Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of [[TP53]].
|date=01.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941676
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106910
}}
}}
==RBP1==
==G6PC3==


* {{medline-title
* {{medline-title
|title=The SR proteins SF2 and [[RBP1]] regulate triglyceride storage in the fat body of Drosophila.
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|date=27.08.2019
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277943
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.151
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
}}
}}
==FGFR2==
==GAB2==


* {{medline-title
* {{medline-title
|title=Oncogenic mutations in histologically normal endometrium: the new normal?
|title=Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936.
|date=10.2019
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29207374
|full-text-url=https://sci-hub.do/10.1002/path.5314
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764388
}}
}}
==SUCNR1==
==GABARAP==


* {{medline-title
* {{medline-title
|title=[The effect of Mexidol on cerebral mitochondriogenesis at a young age and during aging].
|title=Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy.
|date=2020
|date=18.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105271
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32811819
|full-text-url=https://sci-hub.do/10.17116/jnevro202012001162
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434891
}}
}}
==MMP12==
==GADD45B==


* {{medline-title
* {{medline-title
|title=Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for [[MMP12]] through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice.
|title=Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging?
|date=01.10.2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814604
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156709
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1601696
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529819
}}
}}
==STN1==
==GALC==


* {{medline-title
* {{medline-title
|title=[[CTC1]]-[[STN1]] coordinates G- and C-strand synthesis to regulate telomere length.
|title=Analysis of age-related changes in psychosine metabolism in the human brain.
|date=08.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774655
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29481565
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826537
}}
}}
==NEO1==
==GATA1==


* {{medline-title
* {{medline-title
|title=Neogenin-1 distinguishes between myeloid-biased and balanced [i]Hoxb5[/i]  mouse long-term hematopoietic stem cells.
|title=Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass.
|date=10.12.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754028
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31299382
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708771
}}
}}
==CNTF==
==GATA6==


* {{medline-title
* {{medline-title
|title=Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha.
|title=GATA Regulation and Function During the Ovarian Life Cycle.
|date=01.10.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30861131
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544631
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656591
|full-text-url=https://sci-hub.do/10.1016/bs.vh.2018.01.014
}}
}}
==DYNC2H1==
==GCAT==


* {{medline-title
* {{medline-title
|title=Role for intraflagellar transport in building a functional transition zone.
|title=Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis.
|date=12.2018
|date=03.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29551589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280794
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2018.02.004
}}
}}
==PHGDH==
==GCK==


* {{medline-title
* {{medline-title
|title=Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase.
|title=The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing.
|date=01.08.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31108107
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31558549
|full-text-url=https://sci-hub.do/10.1016/j.taap.2019.05.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868460
}}
}}
==HSPB6==
==GCNT2==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|date=2019
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
}}
}}
==DTNBP1==
==GDA==


* {{medline-title
* {{medline-title
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|title=Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces.
|date=2017
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436911
}}
}}
==ATG16L1==
==GDF5==


* {{medline-title
* {{medline-title
|title=The [[ATG5]]-binding and coiled coil domains of [[ATG16L1]] maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
|title=An embryonic CaVβ1 isoform promotes muscle mass maintenance via [[GDF5]] signaling in adult mouse.
|date=04.2019
|date=06.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30403914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31694926
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526875
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aaw1131
}}
}}
==TAAR1==
==GDF9==


* {{medline-title
* {{medline-title
|title=Minimal Age-Related Alterations in Behavioral and Hematological Parameters in Trace Amine-Associated Receptor 1 ([[TAAR1]]) Knockout Mice.
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|date=03.2020
|date=18.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31399838
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|full-text-url=https://sci-hub.do/10.1007/s10571-019-00721-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
}}
}}
==MAFB==
==GEN1==


* {{medline-title
* {{medline-title
|title=Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy.
|title=US acculturation and poor sleep among an intergenerational cohort of adult Latinos in Sacramento, California.
|date=01.04.2019
|date=01.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30605403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30544165
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424080
}}
}}
==LRRK1==
==GFRAL==


* {{medline-title
* {{medline-title
|title=Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.
|title=Growth differentiation factor 15 ([[GDF15]]): A survival protein with therapeutic potential in metabolic diseases.
|date=15.11.2017
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29056298
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790643
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693787
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196666
}}
}}
==TECPR2==
==GGCX==


* {{medline-title
* {{medline-title
|title=Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging.
|title=Multiple Modes of Vitamin K Actions in Aging-Related Musculoskeletal Disorders.
|date=01-03.2019
|date=11.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30681437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31212662
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000294
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600274
}}
}}
==CCDC88A==
==GHSR==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=02.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
}}
==NPAS2==
==GIT1==


* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=[[GIT2]]-A keystone in ageing and age-related disease.
|date=21.11.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002
}}
}}
==MAF1==
==GJA8==


* {{medline-title
* {{medline-title
|title=Beyond regulation of pol III: Role of [[MAF1]] in growth, metabolism, aging and cancer.
|title=The impact of [[GJA8]] SNPs on susceptibility to age-related cataract.
|date=04.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407795
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30349978
|full-text-url=https://sci-hub.do/10.1016/j.bbagrm.2018.01.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267713
}}
}}
==MBD2==
==GJC2==


* {{medline-title
* {{medline-title
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|title=Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging.
|date=02.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32629311
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.04.017
}}
}}
==BRD2==
==GLA==


* {{medline-title
* {{medline-title
|title=Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice.
|title=TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25.
|date=2020
|date=17.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32559200
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304595
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012510
}}
}}
==SIK3==
==GLI1==


* {{medline-title
* {{medline-title
|title=Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids.
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|date=25.09.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566214
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518561
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
}}
}}
==SLC52A3==
==GLO1==


* {{medline-title
* {{medline-title
|title=Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.
|title=The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases.
|date=01.11.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29259621
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808726
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723304
}}
}}
==MAP1B==
==GNAQ==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=[[GNAQ]] expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system.
|date=04.07.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31680437
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1111/pcmr.12843
}}
}}
==MGRN1==
==GNE==


* {{medline-title
* {{medline-title
|title=Chronic and age-dependent effects of the spongiform neurodegeneration-associated [[MGRN1]] E3 ubiquitin ligase on mitochondrial homeostasis.
|title=Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2  mice.
|date=06.2019
|date=10.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089807
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33300446
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639055
|full-text-url=https://sci-hub.do/10.1080/15548627.2020.1850008
}}
}}
==PTCH1==
==GNG4==


* {{medline-title
* {{medline-title
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|title=Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for [[GNG4]] and [[KCNQ2]] Genes.
|date=02.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338302
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098
}}
}}
==GZMK==
==GNPAT==


* {{medline-title
* {{medline-title
|title=Comprehensive Profiling of an Aging Immune System Reveals Clonal [[GZMK]]  CD8  T Cells as Conserved Hallmark of Inflammaging.
|title=Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells.
|date=21.11.2020
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33271118
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30128650
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2020.11.005
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1307-2
}}
}}
==HADHA==
==GORAB==


* {{medline-title
* {{medline-title
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.
|title=Examining tissue composition, whole-bone morphology and mechanical behavior of Gorab  mice tibiae: A mouse model of premature aging.
|date=2019
|date=08.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29108851
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695220
}}
}}
==KDM2A==
==GOT1==


* {{medline-title
* {{medline-title
|title=SIRT6 mono-ADP ribosylates [[KDM2A]] to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=25.06.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32584788
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==LIN28B==
==GP1BA==


* {{medline-title
* {{medline-title
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=2017
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==SUZ12==
==GP6==


* {{medline-title
* {{medline-title
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=05.11.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==HIF1A==
==GPBAR1==


* {{medline-title
* {{medline-title
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|title=Activation of the bile acid receptor [[GPBAR1]] (TGR5) ameliorates interleukin-1β (IL-1β)- induced chondrocytes senescence.
|date=07.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119246
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
|full-text-url=https://sci-hub.do/10.1016/j.biopha.2018.06.154
}}
}}
==DGAT1==
==GPC1==


* {{medline-title
* {{medline-title
|title=Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPα-p300/[[DGAT1]] pathway.
|title=Decreased expression of [[GPC1]] in human skin keratinocytes and epidermis during ageing.
|date=02.2018
|date=15.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31430521
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771394
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.110693
}}
}}
==WNT5A==
==GPD2==


* {{medline-title
* {{medline-title
|title=[[WNT5A]] supports viability of senescent human dental follicle cells.
|title=Switching off [[IMMP2L]] signaling drives senescence via simultaneous metabolic alteration and blockage of cell death.
|date=05.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30406314
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808012
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3467-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993829
}}
}}
==HLA-E==
==GPR101==


* {{medline-title
* {{medline-title
|title=Senescent cells evade immune clearance via [[HLA-E]]-mediated NK and CD8  T cell inhibition.
|title=Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent.
|date=03.06.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160572
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663685
}}
}}
==ELL==
==GPR158==


* {{medline-title
* {{medline-title
|title=Exceptional Longevity and Polygenic Risk for Cardiovascular Health.
|title=RbAp48 Protein Is a Critical Component of [[GPR158]]/OCN Signaling and Ameliorates Age-Related Memory Loss.
|date=18.03.2019
|date=23.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30889929
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355501
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471529
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725275
}}
}}
==SUN1==
==GPR173==


* {{medline-title
* {{medline-title
|title=Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging.
|title=Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent.
|date=26.02.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663685
}}
}}
==JUNB==
==GPR19==


* {{medline-title
* {{medline-title
|title=Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of [[JUNB]].
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=19.02.2020
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31806366
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.11.145
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==NTN4==
==GPR37==


* {{medline-title
* {{medline-title
|title=[[EGF]]/[[EGF]]R upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence.
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|date=04.12.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514230
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
}}
}}
==C2CD2==
==GPR37L1==


* {{medline-title
* {{medline-title
|title=Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort.
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|date=20.11.2017
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29158487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696534
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
}}
}}
==WNT7A==
==GPR6==


* {{medline-title
* {{medline-title
|title=Exogenous Expression of [[WNT7A]] in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents.
|title=Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy.
|date=2020
|date=22.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32959881
|full-text-url=https://sci-hub.do/10.2174/1871520620666200521114100
|full-text-url=https://sci-hub.do/10.1093/infdis/jiaa599
}}
}}
==DLC1==
==GPX2==


* {{medline-title
* {{medline-title
|title=Resveratrol promotes oxidative stress to drive [[DLC1]] mediated cellular senescence in cancer cells.
|title=RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells.
|date=15.09.2018
|date=10.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29964052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29020613
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.06.031
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639470
}}
}}
==CETP==
==GPX3==


* {{medline-title
* {{medline-title
|title=Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study.
|title=Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30159092
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814699
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080062
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857780
}}
}}
==GIT1==
==GPX7==


* {{medline-title
* {{medline-title
|title=[[GIT2]]-A keystone in ageing and age-related disease.
|title=Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7.
|date=05.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452267
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659168
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.02.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052468
}}
}}
==UPF1==
==GRB10==


* {{medline-title
* {{medline-title
|title=Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity.
|title=De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver.
|date=21.08.2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28824175
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563511
|full-text-url=https://sci-hub.do/10.1530/JME-18-0018
}}
}}
==SH2B3==
==GRB2==


* {{medline-title
* {{medline-title
|title=Genome-wide meta-analysis associates HLA-DQA1/DRB1 and [[LPA]] and lifestyle factors with human longevity.
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice.
|date=13.10.2017
|date=21.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29030599
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397
}}
}}
==DEPDC5==
==GREM1==


* {{medline-title
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|title=[[GREM1]] inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells.
|date=05.2018
|date=09.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151168
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
|full-text-url=https://sci-hub.do/10.1080/03008207.2020.1736054
}}
}}
==CASS4==
==GREM2==


* {{medline-title
* {{medline-title
|title=Genetic Biomarkers on Age-Related Cognitive Decline.
|title=Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis.
|date=2017
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29209239
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31709279
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831850
}}
}}
==ZNF396==
==GRID1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies.
|date=15.11.2018
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109663
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1016/j.atherosclerosis.2020.02.005
}}
}}
==MUC5AC==
==GRIN2B==


* {{medline-title
* {{medline-title
|title=InflammAging at Ocular Surface: Clinical and Biomolecular Analyses in Healthy Volunteers.
|title=Medial temporal lobe atrophy relates more strongly to sleep-wake rhythm fragmentation than to age or any other known risk.
|date=01.04.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31022299
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29864525
|full-text-url=https://sci-hub.do/10.1167/iovs.18-25822
|full-text-url=https://sci-hub.do/10.1016/j.nlm.2018.05.017
}}
}}
==TNPO3==
==GRK4==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=10.2019
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==GCK==
==GRK6==


* {{medline-title
* {{medline-title
|title=The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing.
|title=Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity.
|date=12.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31558549
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304635
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868460
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801044
}}
}}
==ZFHX3==
==GRM2==


* {{medline-title
* {{medline-title
|title=Shift work, DNA methylation and epigenetic age.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=01.10.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30879037
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857743
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==NCK2==
==GRM3==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk.
|date=10.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32203495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://sci-hub.do/10.1038/s41593-020-0604-z
}}
}}
==TGFBR2==
==GSN==


* {{medline-title
* {{medline-title
|title=TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
|title=Oral administration of alcalase potato protein hydrolysate-APPH attenuates high fat diet-induced cardiac complications via TGF-β/[[GSN]] axis in aging rats.
|date=08.05.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31068441
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30240538
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102613
|full-text-url=https://sci-hub.do/10.1002/tox.22651
}}
}}
==ALDOA==
==GSTA1==


* {{medline-title
* {{medline-title
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=06.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==SLC24A5==
==GSTK1==


* {{medline-title
* {{medline-title
|title=[A question of colour].
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=01.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29384103
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://sci-hub.do/10.1051/medsci/20183401020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==HSPA5==
==GSTM2==


* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage.
|date=08.2019
|date=07.07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32574561
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342013
}}
}}
==SKAP2==
==GSTM3==


* {{medline-title
* {{medline-title
|title=Longevity-related molecular pathways are subject to midlife "switch" in humans.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=08.2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168962
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612641
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==UACA==
==GSTO1==


* {{medline-title
* {{medline-title
|title=Knockdown of [i][[UACA]][/i] inhibitsproliferation and invasion and promotes senescence of hepatocellular carcinoma cells.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31949867
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962967
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==UBE4B==
==GSTP1==


* {{medline-title
* {{medline-title
|title=CircRNAs in the tree shrew ([i]Tupaia belangeri[/i]) brain during postnatal development and aging.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=30.04.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29723158
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==CUL3==
==GSTT1==


* {{medline-title
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=05.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==SFPQ==
==GSTT2==


* {{medline-title
* {{medline-title
|title=Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=08.04.2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32267831
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185106
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==PEX5==
==GSTZ1==


* {{medline-title
* {{medline-title
|title=Aging lowers [[PEX5]] levels in cortical neurons in male and female mouse brains.
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|date=09.2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32777345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484460
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
}}
}}
==RELA==
==GUK1==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Characterization of the impact of GMP/GDP synthesis inhibition on replicative lifespan extension in yeast.
|date=12.2017
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32232569
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367712
}}
}}
==THBS4==
==GYS2==


* {{medline-title
* {{medline-title
|title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment.
|title=In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers.
|date=18.06.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986936
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664
|full-text-url=https://sci-hub.do/10.1111/jpn.12831
}}
}}
==TTL==
==GZMK==


* {{medline-title
* {{medline-title
|title=Longitudinal Associations of Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio with Biomarkers of Oxidative Stress in Older Adults: Results of a Large Cohort Study.
|title=Comprehensive Profiling of an Aging Immune System Reveals Clonal [[GZMK]]  CD8  T Cells as Conserved Hallmark of Inflammaging.
|date=2020
|date=21.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31986512
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33271118
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098284
|full-text-url=https://sci-hub.do/10.1016/j.immuni.2020.11.005
}}
}}
==AKT2==
==HADHA==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells.
|date=02.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30622695
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317223
}}
}}
==SCN2B==
==HAMP==


* {{medline-title
* {{medline-title
|title=MicroRNA‑449a regulates the progression of brain aging by targeting [[SCN2B]] in SAMP8 mice.
|title=A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity.
|date=04.2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32124967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29408220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053848
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.01.044
}}
}}
==TRAF2==
==HAP1==


* {{medline-title
* {{medline-title
|title=The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium.
|title=The longevity SNP rs2802292 uncovered: [[HSF1]] activates stress-dependent expression of [[FOXO3]] through an intronic enhancer.
|date=12.2019
|date=20.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31042012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711781
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009585
}}
}}
==STK32C==
==HAS2==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts.
|date=25.07.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7
}}
}}
==RAF1==
==HAX1==


* {{medline-title
* {{medline-title
|title=Circular [i]ANRIL[/i] isoforms switch from repressors to activators of [i]p15/CDKN2B[/i] expression during [[RAF1]] oncogene-induced senescence.
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|date=29.09.2020
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32862732
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|full-text-url=https://sci-hub.do/10.1080/15476286.2020.1812910
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
}}
}}
==VPS29==
==HBD==


* {{medline-title
* {{medline-title
|title=Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development.
|title=Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection.
|date=16.01.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485713
}}
}}
==TPRKB==
==HBM==


* {{medline-title
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|title=The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis.
|date=11.04.2019
|date=25.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31553309
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781972
}}
}}
==DPYSL2==
==HCN4==


* {{medline-title
* {{medline-title
|title=Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease.
|title=Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels.
|date=2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31733664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288034
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939615
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934612
}}
}}
==EIF2B2==
==HCRT==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Age-related central regulation of orexin and [[NPY]] in the short-lived African killifish Nothobranchius furzeri.
|date=06.2018
|date=15.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30666646
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://sci-hub.do/10.1002/cne.24638
}}
}}
==ELOVL6==
==HDAC10==


* {{medline-title
* {{medline-title
|title=An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
|title=Middle-aged female rats lack changes in histone H3 acetylation in the anterior hypothalamus observed in young females on the day of a luteinizing hormone surge.
|date=06.2019
|date=17.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30357574
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31434815
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1392-2
|full-text-url=https://sci-hub.do/10.5582/bst.2019.01162
}}
}}
==G6PC3==
==HDAC11==


* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|date=13.11.2018
|date=19.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
}}
}}
==RPL30==
==HDAC8==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.
|date=2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771
}}
}}
==AKAP12==
==HDC==


* {{medline-title
* {{medline-title
|title=A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter.
|title=Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells.
|date=05.2018
|date=07.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29314444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918158
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.02.092
}}
}}
==CD72==
==HES1==


* {{medline-title
* {{medline-title
|title=Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation.
|title=A Single-Cell Transcriptomic Atlas of Human Skin Aging.
|date=2019
|date=23.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30930899
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33238152
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428705
|full-text-url=https://sci-hub.do/10.1016/j.devcel.2020.11.002
}}
}}
==RPL31==
==HHLA2==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma.
|date=2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30768970
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://sci-hub.do/10.1016/j.jtho.2019.01.024
}}
}}
==PEX19==
==HIF1A==


* {{medline-title
* {{medline-title
|title=A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells.
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|date=02.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31854076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996960
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
}}
}}
==TRAV1-2==
==HIF3A==


* {{medline-title
* {{medline-title
|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers.
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|date=05.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
}}
}}
==CAP2==
==HIRA==


* {{medline-title
* {{medline-title
|title=Targeting MRTF/[[SRF]] in [[CAP2]]-dependent dilated cardiomyopathy delays disease onset.
|title=Pak2 kinase promotes cellular senescence and organismal aging.
|date=21.03.2019
|date=02.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30762586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31209047
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613284
}}
}}
==MDK==
==HJV==


* {{medline-title
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|title=Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting.
|date=20.06.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30884219
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596404
}}
}}
==AKTIP==
==HK2==


* {{medline-title
* {{medline-title
|title=Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits.
|title=Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury.
|date=08.2018
|date=11.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29635765
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052474
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811244
}}
}}
==SPRTN==
==HLA-DMA==


* {{medline-title
* {{medline-title
|title=Tandem Deubiquitination and Acetylation of [[SPRTN]] Promotes DNA-Protein Crosslink Repair and Protects against Aging.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=03.09.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32649882
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484104
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==SENP1==
==HLA-DPA1==


* {{medline-title
* {{medline-title
|title=Aging-related SUMOylation pattern in the cortex and blood plasma of wild type mice.
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|date=06.03.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325714
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.01.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
}}
}}
==IL1R2==
==HLA-DQA1==


* {{medline-title
* {{medline-title
|title=Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin.
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|date=01.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28777886
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
}}
}}
==CXCR6==
==HLA-DQB1==


* {{medline-title
* {{medline-title
|title=[[CXCR6]] Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and [[CD4]]  T-Cell-Dependent Control of Senescence.
|title=Identification of new genetic variants of [[HLA-DQB1]] associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population.
|date=05.2019
|date=10.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30710528
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129831
|full-text-url=https://sci-hub.do/10.1053/j.gastro.2019.01.247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723689
}}
}}
==CD48==
==HLA-DRB1==


* {{medline-title
* {{medline-title
|title=Genetic overexpression of [[COMP]]-Ang1 impairs BM microenvironment and induces senescence of BM HSCs.
|title=The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle.
|date=15.05.2018
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29604278
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32942037
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.210
|full-text-url=https://sci-hub.do/10.1016/j.autrev.2020.102670
}}
}}
==GATA1==
==HLA-E==


* {{medline-title
* {{medline-title
|title=Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass.
|title=Senescent cells evade immune clearance via [[HLA-E]]-mediated NK and CD8  T cell inhibition.
|date=10.2019
|date=03.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31299382
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160572
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547655
}}
}}
==MPHOSPH6==
==HMGA1==


* {{medline-title
* {{medline-title
|title=Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length.
|title=Characterization of [i][[HMGA1]]P6[/i] transgenic mouse embryonic fibroblasts.
|date=05.03.2020
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32787507
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513866
}}
}}
==CXCL17==
==HMGCS1==


* {{medline-title
* {{medline-title
|title=[Age-related aspects of the involvement of heat shock proteins in the pathogenesis of osteoarthritis].
|title=The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain.
|date=2017
|date=15.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28849876
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30125687
|full-text-url=https://sci-hub.do/10.1016/j.neuroscience.2018.08.003
}}
==HNF4A==


* {{medline-title
|title=Hepatocyte Nuclear Factor-4α P2 Promoter Variants Are Associated With the Risk of Metabolic Syndrome and Testosterone Deficiency in Aging Taiwanese Men.
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415809
|full-text-url=https://sci-hub.do/10.1016/j.jsxm.2018.09.012
}}
}}
==ATF3==
==HNRNPA0==


* {{medline-title
* {{medline-title
|title=[[ATF3]] represses [[PINK1]] gene transcription in lung epithelial cells to control mitochondrial homeostasis.
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|date=04.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29363258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847866
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
}}
}}
==NRL==
==HNRNPA1==


* {{medline-title
* {{medline-title
|title=Development of a cyclophosphamide stress test to predict resilience to aging in mice.
|title=[[HNRNPA1]]-mediated 3' UTR length changes of [i]HN1[/i] contributes to cancer- and senescence-associated phenotypes.
|date=12.2020
|date=30.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32613492
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257225
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00222-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660030
}}
}}
==SCO1==
==HNRNPM==


* {{medline-title
* {{medline-title
|title=Real-Time PCR Analysis of Metabolism-Related Genes in a Long-Lived Model of C. elegans.
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|date=2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32219749
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|full-text-url=https://sci-hub.do/10.1007/978-1-0716-0471-7_12
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
}}
}}
==KLF1==
==HOXA3==


* {{medline-title
* {{medline-title
|title=Mutant [[KLF1]] in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=24.08.2018
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30143664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==MYCN==
==HOXA4==


* {{medline-title
* {{medline-title
|title=Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells.
|title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes.
|date=2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947931
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529
}}
}}
==ARL13B==
==HOXB7==


* {{medline-title
* {{medline-title
|title=[[ARL13B]], a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments.
|title=Impact of [[HOXB7]] overexpression on human adipose-derived mesenchymal progenitors.
|date=20.02.2019
|date=19.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890185
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423808
}}
}}
==CPNE1==
==HOXC4==


* {{medline-title
* {{medline-title
|title=Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=04.12.2020
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33274830
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://sci-hub.do/10.1111/acel.13276
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==PLN==
==HOXD8==


* {{medline-title
* {{medline-title
|title=An analysis of the costs of treating aged patients in a large clinical hospital in Poland under the pressure of recent demographic trends.
|title=Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts.
|date=2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849838
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212232
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431633
}}
}}
==POLG2==
==HPD==


* {{medline-title
* {{medline-title
|title=An N-Ethyl-N-Nitrosourea (ENU)-Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice.
|title=Protein-Amino Acid Metabolism Disarrangements: The Hidden Enemy of Chronic Age-Related Conditions.
|date=03.2019
|date=22.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30395686
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29565819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446808
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946176
}}
}}
==REV1==
==HPSE==


* {{medline-title
* {{medline-title
|title=[[REV1]] inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks.
|title=Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin.
|date=17.11.2020
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168727
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32159248
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682577
|full-text-url=https://sci-hub.do/10.1002/cbin.11339
}}
}}
==AIDA==
==HRG==


* {{medline-title
* {{medline-title
|title=Identification of Postharvest Senescence Regulators Through Map-Based Cloning Using Detached Arabidopsis Inflorescences as a Model Tissue.
|title=Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice.
|date=2018
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392668
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29021712
|full-text-url=https://sci-hub.do/10.1007/978-1-4939-7672-0_17
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628339
}}
}}
==CRBN==
==HRH4==


* {{medline-title
* {{medline-title
|title=Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity.
|title=Histamime Receptor H4 as a New Therapeutic Target for Age-related Macular Degeneration.
|date=24.04.2020
|date=11.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32332723
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30074739
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181703
}}
==LRRC8B==


* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==SHANK3==
==HS2ST1==


* {{medline-title
* {{medline-title
|title=Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background.
|title=Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity.
|date=10.10.2018
|date=31.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30305163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31940721
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180595
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999708
}}
}}
==SPATS2L==
==HSD17B14==


* {{medline-title
* {{medline-title
|title=Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.
|title=Bisphenol A induces DSB-[[ATM]]-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts.
|date=02.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585438
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29275510
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818258
|full-text-url=https://sci-hub.do/10.1007/s00204-017-2150-3
}}
}}
==TAS1R2==
==HSD17B4==


* {{medline-title
* {{medline-title
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects.
|title=Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein-2 deficiency.
|date=18.10.2018
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29341299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
|full-text-url=https://sci-hub.do/10.1111/bpa.12586
}}
}}
==CYP2C9==
==HSD3B2==


* {{medline-title
* {{medline-title
|title=Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.
|title=11-Oxygenated C19 Steroids Do Not Decline With Age in Women.
|date=12.2017
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28986475
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753518
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5697442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525564
}}
}}
==TCTA==
==HSP90AA1==
 
* {{medline-title
|title=Exciplex-Forming Cohost for High Efficiency and High Stability Phosphorescent Organic Light-Emitting Diodes.
|date=17.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29265796
|full-text-url=https://sci-hub.do/10.1021/acsami.7b15034
}}
==DRAM2==


* {{medline-title
* {{medline-title
Строка 8007: Строка 7927:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==PCCB==
==HSPA13==


* {{medline-title
* {{medline-title
|title=Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism.
|title=Genetic associations with age of menopause in familial longevity.
|date=03.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29159707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==SCN2A==
==HSPA1L==


* {{medline-title
* {{medline-title
|title=Na 1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age.
|title=Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the [[HSPA1L]]-mitophagy pathway.
|date=09.09.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31501495
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31965731
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733925
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059143
}}
}}
==ARNTL==
==HSPA5==


* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=21.11.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
==CR2==
==HSPB1==


* {{medline-title
* {{medline-title
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|title=The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity.
|date=19.01.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31102684
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
|full-text-url=https://sci-hub.do/10.1016/j.diabres.2019.05.009
}}
}}
==CYP24A1==
==HSPB6==


* {{medline-title
* {{medline-title
|title=Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism.
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=22.02.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29470404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852823
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
==HAX1==
==HSPG2==


* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=13.11.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==NPBWR1==
==HTRA1==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|date=12.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
}}
}}
==FKBP5==
==HYOU1==


* {{medline-title
* {{medline-title
|title=Epigenetic upregulation of [[FKBP5]] by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk.
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|date=04.06.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113877
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561294
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
}}
}}
==GREM2==
==IAPP==


* {{medline-title
* {{medline-title
|title=Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis.
|title=Protein aggregates and proteostasis in aging: Amylin and β-cell function.
|date=12.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31709279
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580826
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831850
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.03.010
}}
}}
==GSTA1==
==ICAM1==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=An Inhibitor of Activated Blood Coagulation Factor X Shows Anti-Endothelial Senescence and Anti-Atherosclerotic Effects.
|date=12.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31266015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://sci-hub.do/10.1159/000499975
}}
}}
==TNNI1==
==ICE1==


* {{medline-title
* {{medline-title
|title=Regular aerobic exercise-ameliorated troponin I carbonylation to mitigate aged rat soleus muscle functional recession.
|title=ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1.
|date=05.2019
|date=19.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820991
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783407
|full-text-url=https://sci-hub.do/10.1113/EP087564
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031079
}}
}}
==SMOX==
==ID2==


* {{medline-title
* {{medline-title
|title=Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=14.02.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29443878
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872171
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==GRK6==
==IFI27==


* {{medline-title
* {{medline-title
|title=Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity.
|title=Ultraviolet B irradiation-induced keratinocyte senescence and impaired development of 3D epidermal reconstruct.
|date=12.2019
|date=01.06.2021
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33151171
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801044
|full-text-url=https://sci-hub.do/10.2478/acph-2021-0011
}}
}}
==PRM1==
==IFIH1==


* {{medline-title
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|date=01.02.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
}}
}}
==MAX==
==IFIT1==


* {{medline-title
* {{medline-title
|title=Validation of the MedUseQ: A Self-Administered Screener for Older Adults to Assess Medication Use Problems.
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|date=10.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656678
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|full-text-url=https://sci-hub.do/10.1177/0897190018766789
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
}}
}}
==LHCGR==
==IFITM1==


* {{medline-title
* {{medline-title
|title=Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats.
|title=Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection.
|date=11.10.2020
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050653
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230210
}}
}}
==LCN2==
==IFITM3==


* {{medline-title
* {{medline-title
|title=Anthropometric and glucometabolic changes in an aged mouse model of lipocalin-2 overexpression.
|title=Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein [[IFITM3]].
|date=01.2019
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082752
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242426
|full-text-url=https://sci-hub.do/10.1038/s41366-018-0171-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613042
}}
}}
==ICAM1==
==IFNG==


* {{medline-title
* {{medline-title
|title=An Inhibitor of Activated Blood Coagulation Factor X Shows Anti-Endothelial Senescence and Anti-Atherosclerotic Effects.
|title=Glutathione Peroxidase 3 Delivered by hiPSC-[[MSC]]s Ameliorated Hepatic IR Injury via Inhibition of Hepatic Senescence.
|date=2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31266015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29290803
|full-text-url=https://sci-hub.do/10.1159/000499975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743470
}}
}}
==DPP6==
==IFT140==


* {{medline-title
* {{medline-title
|title=A novel structure associated with aging is augmented in the [[DPP6]]-KO mouse brain.
|title=The Role of [[IFT140]] in Osteogenesis of Adult Mice Long Bone.
|date=23.11.2020
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33225987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31034313
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682109
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669857
}}
}}
==PFKFB3==
==IGF2BP3==


* {{medline-title
* {{medline-title
|title=DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system.
|title=Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth.
|date=05.2018
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888162
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871568
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b00833
}}
}}
==GPR37==
==IGF2R==


* {{medline-title
* {{medline-title
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|title=Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks.
|date=08.2018
|date=05-06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29554514
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
|full-text-url=https://sci-hub.do/10.1016/j.archger.2018.03.004
}}
}}
==HYOU1==
==IGFBP4==


* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey.
|date=08.2019
|date=11.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31601169
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788010
}}
}}
==GUK1==
==IGFBP6==


* {{medline-title
* {{medline-title
|title=Characterization of the impact of GMP/GDP synthesis inhibition on replicative lifespan extension in yeast.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=08.2020
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32232569
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367712
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==AQP4==
==IGFBP7==


* {{medline-title
* {{medline-title
|title=Overexpression of Slit2 improves function of the paravascular pathway in the aging mouse brain.
|title=Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7.
|date=10.2018
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30085336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31904196
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108881
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031646
}}
}}
==ELANE==
==IGHD==


* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=Growth Hormone Deficiency: Health and Longevity.
|date=13.11.2018
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576428
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416709
}}
}}
==SLC16A7==
==IGSF1==


* {{medline-title
* {{medline-title
|title=Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach.
|title=Age-related gene and miRNA expression changes in airways of healthy individuals.
|date=23.10.2020
|date=06.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33095951
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842487
|full-text-url=https://sci-hub.do/10.1111/jdv.17014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403379
}}
}}
==CD2==
==IHH==


* {{medline-title
* {{medline-title
|title=Adaptive NKG2C CD57  Natural Killer Cell and Tim-3 Expression During Viral Infections.
|title=Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway.
|date=2018
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29731749
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32235006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919961
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185126
}}
}}
==ERCC8==
==IKBKB==


* {{medline-title
* {{medline-title
|title=Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=12.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31385397
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826141
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
==MFSD2A==
==IL13==


* {{medline-title
* {{medline-title
|title=Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease.
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|date=20.12.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31861865
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981746
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
}}
}}
==SDC2==
==IL15==


* {{medline-title
* {{medline-title
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|title=Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of [[IL15]].
|date=01.10.2017
|date=27.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32221610
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
|full-text-url=https://sci-hub.do/10.1093/ageing/afaa035
}}
}}
==ACD==
==IL17RA==


* {{medline-title
* {{medline-title
|title=Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging.
|title=Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon.
|date=02.12.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31792241
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29039977
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889148
|full-text-url=https://sci-hub.do/10.1080/07420528.2017.1361436
}}
}}
==NRARP==
==IL18==


* {{medline-title
* {{medline-title
|title=Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing [[NRARP]].
|title=Aging and the Inflammasomes.
|date=10.11.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30274778
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30536177
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.09.045
|full-text-url=https://sci-hub.do/10.1007/978-3-319-89390-7_13
}}
}}
==CTNS==
==IL1R2==


* {{medline-title
* {{medline-title
|title=Reducing [[INS]]-[[IGF1]] signaling protects against non-cell autonomous vesicle rupture caused by [[SNCA]] spreading.
|title=Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin.
|date=05.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31354022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28777886
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7144869
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721243
}}
}}
==TYK2==
==IL22==


* {{medline-title
* {{medline-title
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|date=04.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
}}
}}
==GPR158==
==IL2RA==


* {{medline-title
* {{medline-title
|title=RbAp48 Protein Is a Critical Component of [[GPR158]]/OCN Signaling and Ameliorates Age-Related Memory Loss.
|title=Dynamic demethylation of the [[IL2RA]] promoter during in vitro CD4+ T cell activation in association with [[IL2RA]] expression.
|date=23.10.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30355501
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30096258
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725275
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140818
}}
}}
==NPC2==
==IL4==


* {{medline-title
* {{medline-title
|title=Attenuation of the Niemann-Pick type [[C2]] disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2.
|title=Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia.
|date=08.2018
|date=01.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29655638
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29122767
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2018.04.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756472
}}
}}
==RAI1==
==IL6ST==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|date=25.07.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
}}
}}
==TSHB==
==IL9==


* {{medline-title
* {{medline-title
|title=Adipose [[TSHB]] in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence.
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|date=2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448824
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|full-text-url=https://sci-hub.do/10.1159/000495170
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
}}
}}
==ABCG5==
==ILDR1==


* {{medline-title
* {{medline-title
|title=2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms.
|title=Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment.
|date=01.04.2019
|date=23.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30939745
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31645637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479705
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811684
}}
}}
==SOS1==
==IMMP2L==


* {{medline-title
* {{medline-title
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice.
|title=Switching off [[IMMP2L]] signaling drives senescence via simultaneous metabolic alteration and blockage of cell death.
|date=21.01.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993829
}}
}}
==SLC30A1==
==ING1==


* {{medline-title
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|title=Impaired DNA demethylation of C/EBP sites causes premature aging.
|date=01.12.2017
|date=01.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29884649
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049513
}}
}}
==NDUFS1==
==INHBA==


* {{medline-title
* {{medline-title
|title=Mapping the protein phosphorylation sites in human mitochondrial complex I (NADH: Ubiquinone oxidoreductase): A bioinformatics study with implications for brain aging and neurodegeneration.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=01.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29499254
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2018.02.004
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==SELENOV==
==INHBE==


* {{medline-title
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|date=03.2019
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
}}
}}
==PRMT1==
==INPP4B==


* {{medline-title
* {{medline-title
|title=Reactive oxygen species extend insect life span using components of the insulin-signaling pathway.
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|date=12.09.2017
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847950
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604040
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
}}
}}
==HAS2==
==INPP5A==


* {{medline-title
* {{medline-title
|title=Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=01.2018
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29063508
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://sci-hub.do/10.1007/s13577-017-0185-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==KDM2B==
==IP6K1==


* {{medline-title
* {{medline-title
|title=Identification of Structural Elements of the Lysine Specific Demethylase 2B CxxC Domain Associated with Replicative Senescence Bypass in Primary Mouse Cells.
|title=The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle.
|date=06.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31552262
|full-text-url=https://sci-hub.do/10.1007/s10930-020-09895-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746962
}}
}}
==ITGB1==
==IPMK==


* {{medline-title
* {{medline-title
|title=Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.
|title=Inositol Polyphosphate Multikinase ([i][[IPMK]][/i]), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity.
|date=05.2018
|date=08.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29599141
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30744060
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.117.310685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410091
}}
}}
==EFEMP1==
==IRF1==


* {{medline-title
* {{medline-title
|title=A novel age-related venous amyloidosis derived from [[EGF]]-containing fibulin-like extracellular matrix protein 1.
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|date=04.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30565683
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|full-text-url=https://sci-hub.do/10.1002/path.5203
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
}}
}}
==S100A12==
==IRF5==


* {{medline-title
* {{medline-title
|title=Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model.
|title=Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice.
|date=06.07.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991479
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28905935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672072
}}
}}
==ATG10==
==IRGM==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|date=10.2019
|date=09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
}}
}}
==PSMG1==
==ISG15==


* {{medline-title
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|date=03.2018
|date=14.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
}}
}}
==NDRG1==
==ITGA2B==


* {{medline-title
* {{medline-title
|title=Cx43 phosphorylation-mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein [[NDRG1]].
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|date=02.08.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189653
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682735
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
}}
}}
==AP2B1==
==ITGA3==


* {{medline-title
* {{medline-title
|title=Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice.
|title=A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells.
|date=20.12.2019
|date=17.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31860870
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32807231
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430027
}}
}}
==UGT2B28==
==ITGA5==


* {{medline-title
* {{medline-title
|title=Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a [[UGT2B28]] genomic variation.
|title=Kaempferol alleviates the reduction of developmental competence during aging of porcine oocytes.
|date=05.12.2019
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31805979
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31486245
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896495
|full-text-url=https://sci-hub.do/10.1111/asj.13280
}}
}}
==PTGS2==
==ITGA6==


* {{medline-title
* {{medline-title
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism.
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=21.05.2019
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
}}
==MCM5==
==ITGAM==


* {{medline-title
* {{medline-title
|title=Changes in [[MCM2]]-7 proteins at senescence.
|title=Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging.
|date=27.07.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31732940
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
|full-text-url=https://sci-hub.do/10.1007/978-3-030-28524-1_11
}}
}}
==LAMA2==
==ITGB1==


* {{medline-title
* {{medline-title
|title=[Alu insertion-deletion polymorphism of [[COL13A1]] and [[LAMA2]] genes: The analysis of association with longevity].
|title=Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.
|date=10.2016
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369589
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29599141
 
|full-text-url=https://sci-hub.do/10.1161/ATVBAHA.117.310685
}}
}}
==ACVR1==
==ITGB2==


* {{medline-title
* {{medline-title
|title=Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome.
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31998237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966325
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
}}
}}
==VASP==
==ITGB4==


* {{medline-title
* {{medline-title
|title=Reversal of Aging-Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein-Protein Interfaces.
|title=[[ITGB4]] deficiency induces senescence of airway epithelial cells through p53 activation.
|date=18.07.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021807
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30636108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201469
|full-text-url=https://sci-hub.do/10.1111/febs.14749
}}
}}
==PPM1A==
==ITK==


* {{medline-title
* {{medline-title
|title=The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1.
|title=Does Tetralogy of Fallot affect brain aging? A proof-of-concept study.
|date=03.08.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31382626
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30130369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723262
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103512
}}
}}
==RNF13==
==ITPR2==


* {{medline-title
* {{medline-title
|title=The effects of environmental stressors on candidate aging associated genes.
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling.
|date=08.2020
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32344118
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110952
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923
}}
}}
==VSIG4==
==JAGN1==


* {{medline-title
* {{medline-title
|title=Immune checkpoint protein [[VSIG4]] as a biomarker of aging in murine adipose tissue.
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|date=10.2020
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856419
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
}}
}}
==AMHR2==
==JAK3==


* {{medline-title
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|date=03.2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
}}
}}
==ATP6V1E1==
==JAM3==


* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=07.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
}}
==TGDS==
==JARID2==


* {{medline-title
* {{medline-title
|title=The evaluation and design of a short depression screening tool in Turkish older adults.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=10.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29560848
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://sci-hub.do/10.1017/S1041610218000236
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==CDKN1C==
==JDP2==


* {{medline-title
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|title=Jun dimerization protein 2 controls hypoxia-induced replicative senescence via both the p16 -pRb and Arf-p53 pathways.
|date=18.03.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29123987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666393
}}
}}
==CXCL14==
==JUNB==


* {{medline-title
* {{medline-title
|title=Identification of genes associated with endometrial cell aging.
|title=Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of [[JUNB]].
|date=01.12.2020
|date=19.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33258951
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31806366
|full-text-url=https://sci-hub.do/10.1093/molehr/gaaa078
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.11.145
}}
}}
==EWSR1==
==KAT6B==


* {{medline-title
* {{medline-title
|title=[[EWSR1]], a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways.
|title=Aging-associated decrease in the histone acetyltransferase [[KAT6B]] is linked to altered hematopoietic stem cell differentiation.
|date=01.07.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30481590
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32014431
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179256
}}
}}
==RNF10==
==KCNAB3==


* {{medline-title
* {{medline-title
|title=Reduced RING finger protein 10 expression in macrophages is associated with aging-related inflammation.
|title=Tracking age-correlated DNA methylation markers in the young.
|date=28.11.2020
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33249776
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29933125
|full-text-url=https://sci-hub.do/10.1002/2211-5463.13049
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.06.011
}}
}}
==SMO==
==KCNB1==


* {{medline-title
* {{medline-title
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|title=Oxidation of [[KCNB1]] potassium channels in the murine brain during aging is associated with cognitive impairment.
|date=02.2019
|date=14.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30922570
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471606
}}
}}
==ERCC2==
==KCNC3==


* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird.
|date=06.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723
}}
}}
==NDRG2==
==KCNE4==


* {{medline-title
* {{medline-title
|title=[[NDRG2]] Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain.
|title=Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice.
|date=04.01.2020
|date=29.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31947996
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29844497
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982267
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974354
}}
}}
==AMFR==
==KCNK2==


* {{medline-title
* {{medline-title
|title=Mice heterozygous for the Cdh23/Ahl1 mutation show age-related deficits in auditory temporal processing.
|title=Brain age prediction using deep learning uncovers associated sequence variants.
|date=09.2019
|date=27.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31247458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31776335
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732241
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881321
}}
}}
==DES==
==KCNQ2==


* {{medline-title
* {{medline-title
|title=Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis.
|title=Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for [[GNG4]] and [[KCNQ2]] Genes.
|date=20.03.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29558926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338302
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859529
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098
}}
}}
==UBB==
==KCNQ4==


* {{medline-title
* {{medline-title
|title=Different Expression Levels of Human Mutant Ubiquitin B  ([[UBB]] ) Can Modify Chronological Lifespan or Stress Resistance of [i]Saccharomyces cerevisiae[/i].
|title=Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss.
|date=2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29950972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32327991
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008557
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160671
}}
}}
==RAD23A==
==KCTD12==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort.
|date=2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32970748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7514036
}}
}}
==TSG101==
==KDM2A==


* {{medline-title
* {{medline-title
|title=Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging.
|title=SIRT6 mono-ADP ribosylates [[KDM2A]] to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair.
|date=01.09.2019
|date=25.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220525
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32584788
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343504
}}
}}
==HNRNPA1==
==KDM2B==


* {{medline-title
* {{medline-title
|title=[[HNRNPA1]]-mediated 3' UTR length changes of [i]HN1[/i] contributes to cancer- and senescence-associated phenotypes.
|title=Identification of Structural Elements of the Lysine Specific Demethylase 2B CxxC Domain Associated with Replicative Senescence Bypass in Primary Mouse Cells.
|date=30.06.2019
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32270414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660030
|full-text-url=https://sci-hub.do/10.1007/s10930-020-09895-z
}}
}}
==ATP2B1==
==KDM3A==


* {{medline-title
* {{medline-title
|title=Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries.
|title=[[KDM3A]] and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization.
|date=10.2017
|date=22.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28795531
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704649
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888768
}}
}}
==ANG==
==KDM4A==


* {{medline-title
* {{medline-title
|title=Age-related differences in the cutaneous vascular response to exogenous angiotensin II.
|title=Structure-Based Discovery of a Selective [[KDM5A]] Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines.
|date=01.03.2019
|date=15.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30499715
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30650517
|full-text-url=https://sci-hub.do/10.1152/ajpheart.00509.2018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360022
}}
}}
==PTPN1==
==KDM5A==


* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=Structure-Based Discovery of a Selective [[KDM5A]] Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines.
|date=06.2018
|date=15.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30650517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360022
}}
}}
==GRB10==
==KDM6B==


* {{medline-title
* {{medline-title
|title=De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver.
|title=Histone demethylase [[KDM6B]] regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells.
|date=05.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29555819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30825201
|full-text-url=https://sci-hub.do/10.1530/JME-18-0018
|full-text-url=https://sci-hub.do/10.1002/jcp.28431
}}
}}
==BAZ2B==
==KIF1A==


* {{medline-title
* {{medline-title
|title=Two conserved epigenetic regulators prevent healthy ageing.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=03.2020
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32103178
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2037-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==REC8==
==KIF1B==


* {{medline-title
* {{medline-title
|title=Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice.
|title=[[BDNF]] trafficking and signaling impairment during early neurodegeneration is prevented by moderate physical activity.
|date=10.2018
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30135925
|full-text-url=https://sci-hub.do/10.1007/s11655-018-2835-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084862
}}
}}
==LRP6==
==KIFC3==


* {{medline-title
* {{medline-title
|title=Low-density lipoprotein receptor-related protein 6-mediated signaling pathways and associated cardiovascular diseases: diagnostic and therapeutic opportunities.
|title=Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging.
|date=04.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32076828
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29845728
|full-text-url=https://sci-hub.do/10.1007/s00439-020-02124-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052466
}}
}}
==TRPV6==
==KLB==


* {{medline-title
* {{medline-title
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|title=Infants Uniquely Express High Levels of [[RBM3]] and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain.
|date=01.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399610
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311128
}}
}}
==VHLL==
==KLF1==


* {{medline-title
* {{medline-title
|title=The Monetary Valuation of Lifetime Health Improvement and Life Expectancy Gains in Turkey.
|title=Mutant [[KLF1]] in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis.
|date=29.09.2017
|date=24.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28961227
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30143664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664652
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109071
}}
}}
==POU5F1==
==KLF2==


* {{medline-title
* {{medline-title
|title=Cell quality evaluation with gene expression analysis of spheroids (3D) and adherent (2D) adipose stem cells.
|title=[[KLF2]] induces the senescence of pancreatic cancer cells by cooperating with FOXO4 to upregulate p21.
|date=24.10.2020
|date=01.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33148459
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31866399
|full-text-url=https://sci-hub.do/10.1016/j.gene.2020.145269
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2019.111784
}}
}}
==HDAC10==
==KLF5==


* {{medline-title
* {{medline-title
|title=Middle-aged female rats lack changes in histone H3 acetylation in the anterior hypothalamus observed in young females on the day of a luteinizing hormone surge.
|title=[[EGR1]] promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling.
|date=17.09.2019
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31434815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31201921
|full-text-url=https://sci-hub.do/10.5582/bst.2019.01162
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.06.010
}}
}}
==FDPS==
==KLF6==


* {{medline-title
* {{medline-title
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
|title=Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence.
|date=12.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31824948
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882731
}}
}}
==GDA==
==KLHL22==


* {{medline-title
* {{medline-title
|title=Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces.
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|date=03.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30944897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436911
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
}}
}}
==BOC==
==KPNA2==


* {{medline-title
* {{medline-title
|title=Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations.
|title=Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-[[CRY1]] Transgenic Mice.
|date=01.05.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32140711
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31179341
|full-text-url=https://sci-hub.do/10.1093/jn/nxaa031
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507265
}}
}}
==APLNR==
==KRT15==


* {{medline-title
* {{medline-title
|title=Endothelial [[APLNR]] regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.
|title=Extracellular proteoglycan decorin maintains human hair follicle stem cells.
|date=13.09.2017
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28904225
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320452
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703224
|full-text-url=https://sci-hub.do/10.1111/1346-8138.14678
}}
}}
==LEF1==
==KRT18==


* {{medline-title
* {{medline-title
|title=LncRNA H19 targets miR-22 to modulate H  O  -induced deregulation in nucleus pulposus cell senescence, proliferation, and ECM synthesis through Wnt signaling.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=06.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520849
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://sci-hub.do/10.1002/jcb.26738
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
==RHOB==
==KRT19==


* {{medline-title
* {{medline-title
|title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes.
|title=Characterization of Krt19  allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc.
|date=13.06.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187500
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778700
}}
}}
==SNAI2==
==KY==


* {{medline-title
* {{medline-title
|title=Reawakening of dormant estrogen-dependent human breast cancer cells by bone marrow stroma secretory senescence.
|title=Combination of acupuncture and Chinese herbal formula for elderly adults with mild cognitive impairment: protocol for a randomized controlled trial.
|date=17.08.2018
|date=11.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119678
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30744676
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371495
}}
}}
==UCP3==
==LAG3==


* {{medline-title
* {{medline-title
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats.
|title=T Cell Transcriptional Profiling and Immunophenotyping Uncover [[LAG3]] as a Potential Significant Target of Immune Modulation in Multiple Myeloma.
|date=01.2018
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31445183
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952061
}}
}}
==APPL1==
==LAGE3==


* {{medline-title
* {{medline-title
|title=Insulin and adipokine signaling and their cross-regulation in postmortem human brain.
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|date=12.2019
|date=11.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31539648
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
}}
}}
==DGCR8==
==LAMA2==


* {{medline-title
* {{medline-title
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif.
|title=[Alu insertion-deletion polymorphism of [[COL13A1]] and [[LAMA2]] genes: The analysis of association with longevity].
|date=29.04.2019
|date=10.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369589
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004
 
}}
}}
==VCL==
==LAMA5==


* {{medline-title
* {{medline-title
|title=The effects of different preservation methods on ide (Leuciscus idus) sperm and the longevity of sperm movement.
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
|date=04.2018
|date=05.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397922
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365
|full-text-url=https://sci-hub.do/10.1016/j.cryobiol.2018.01.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
}}
}}
==CDH1==
==LAT==


* {{medline-title
* {{medline-title
|title=Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation.
|title=Is the combined auriculotherapy approach superior to magneto-auriculotherapy alone in aging males with lower urinary tract symptoms? A randomized controlled trial.
|date=15.09.2020
|date=16.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32010971
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30651007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496346
|full-text-url=https://sci-hub.do/10.1080/13685538.2018.1542673
}}
}}
==GP1BA==
==LCN2==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Anthropometric and glucometabolic changes in an aged mouse model of lipocalin-2 overexpression.
|date=15.11.2018
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30082752
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1038/s41366-018-0171-5
}}
}}
==SMC2==
==LDB2==


* {{medline-title
* {{medline-title
|title=The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=10.11.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336977
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.065
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==ACADM==
==LDLR==


* {{medline-title
* {{medline-title
|title=High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats.
|title=Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice.
|date=07.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28888352
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29903737
|full-text-url=https://sci-hub.do/10.1016/j.jfma.2017.08.008
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092113
}}
}}
==SYT7==
==LEF1==


* {{medline-title
* {{medline-title
|title=Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells.
|title=LncRNA H19 targets miR-22 to modulate H  O  -induced deregulation in nucleus pulposus cell senescence, proliferation, and ECM synthesis through Wnt signaling.
|date=28.02.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30647108
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520849
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367206
|full-text-url=https://sci-hub.do/10.1002/jcb.26738
}}
}}
==ATG4D==
==LGALS3==


* {{medline-title
* {{medline-title
|title=Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats.
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|date=17.07.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242723
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b02567
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
}}
}}
==CREBBP==
==LGI1==


* {{medline-title
* {{medline-title
|title=Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms.
|title=Antibody-associated CNS syndromes without signs of inflammation in the elderly.
|date=22.07.2019
|date=03.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31332237
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28878050
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631166
}}
}}
==ADAMTS3==
==LGR6==


* {{medline-title
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|title=Effect of defensins-containing eye cream on periocular rhytids and skin quality.
|date=01.2018
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32614135
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
|full-text-url=https://sci-hub.do/10.1111/jocd.13424
}}
}}
==IGFBP4==
==LHCGR==


* {{medline-title
* {{medline-title
|title=Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey.
|title=Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats.
|date=11.10.2019
|date=11.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31601169
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33050653
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590010
}}
}}
==KY==
==LIFR==


* {{medline-title
* {{medline-title
|title=Combination of acupuncture and Chinese herbal formula for elderly adults with mild cognitive impairment: protocol for a randomized controlled trial.
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.
|date=11.02.2019
|date=15.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30744676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304
}}
}}
==ANGPT2==
==LIN28B==


* {{medline-title
* {{medline-title
|title=Systemic analysis of gene expression profiles in porcine granulosa cells during aging.
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|date=14.11.2017
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29228554
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722506
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
}}
}}
==PF4V1==
==LIPA==


* {{medline-title
* {{medline-title
|title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells.
|title=Influence of Habitual Physical Behavior - Sleeping, Sedentarism, Physical Activity - On Bone Health in Community-Dwelling Older People.
|date=05.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31037056
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476278
}}
}}
==WNK4==
==LMX1A==


* {{medline-title
* {{medline-title
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2.
|title=Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain.
|date=10.2018
|date=13.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30318292
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234859
}}
}}
==RRM1==
==LOXL1==


* {{medline-title
* {{medline-title
|title=α-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1.
|title=A blackberry-dill extract combination synergistically increases skin elasticity.
|date=08.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977294
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32583541
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612645
|full-text-url=https://sci-hub.do/10.1111/ics.12644
}}
}}
==CINP==
==LPAR3==


* {{medline-title
* {{medline-title
|title=Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging.
|title=Upregulated microRNA-15b alleviates ovarian cancer through inhitbition of the PI3K/Akt pathway by targeting [[LPAR3]].
|date=01-03.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30681437
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31140597
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000294
|full-text-url=https://sci-hub.do/10.1002/jcp.28799
}}
}}
==NPM1==
==LRP1==


* {{medline-title
* {{medline-title
|title=Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats.
|title=Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome.
|date=29.11.2019
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31784606
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32268785
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255962
}}
}}
==GRK4==
==LRP2==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis.
|date=15.11.2017
|date=27.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.11.003
}}
}}
==PRMT8==
==LRP6==


* {{medline-title
* {{medline-title
|title=Arginine Methyltransferase [[PRMT8]] Provides Cellular Stress Tolerance in Aging Motoneurons.
|title=Low-density lipoprotein receptor-related protein 6-mediated signaling pathways and associated cardiovascular diseases: diagnostic and therapeutic opportunities.
|date=29.08.2018
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32076828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113905
|full-text-url=https://sci-hub.do/10.1007/s00439-020-02124-8
}}
}}
==FADS1==
==LRP8==


* {{medline-title
* {{medline-title
|title=Aging and [[FADS1]] polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U- C]linoleic acid.
|title=SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating [[LRP8]] and ApoE.
|date=09.2019
|date=02.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31492428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31269452
|full-text-url=https://sci-hub.do/10.1016/j.plefa.2019.07.003
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.06.002
}}
}}
==ATG4B==
==LRRC34==


* {{medline-title
* {{medline-title
|title=Impaired autophagic activity and [[ATG4B]] deficiency are associated with increased endoplasmic reticulum stress-induced lung injury.
|title=The polygenic nature of telomere length and the anti-ageing properties of lithium.
|date=27.08.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30147026
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372618
}}
}}
==PSMD13==
==LRRC8B==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=2019
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==PBX1==
==LRRK1==


* {{medline-title
* {{medline-title
|title=Internalization of the TAT-[[PBX1]] fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence.
|title=Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.
|date=10.2020
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436118
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29056298
|full-text-url=https://sci-hub.do/10.1007/s10529-020-02909-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693787
}}
}}
==PGAP1==
==LTF==


* {{medline-title
* {{medline-title
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|date=07.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
}}
}}
==RBP4==
==LY6D==


* {{medline-title
* {{medline-title
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats].
|title=[[LY6D]]-induced macropinocytosis as a survival mechanism of senescent cells.
|date=08.05.2017
|date=09.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168631
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110
|full-text-url=https://sci-hub.do/10.1074/jbc.RA120.013500
}}
}}
==SAMD12==
==LY86==


* {{medline-title
* {{medline-title
|title=Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom.
|title=Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease.
|date=05.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31280115
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732230
}}
}}
==RXFP3==
==LYG1==


* {{medline-title
* {{medline-title
|title=The [[RXFP3]] receptor is functionally associated with cellular responses to oxidative stress and DNA damage.
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|date=03.12.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794429
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932917
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
}}
}}
==CEL==
==LYST==


* {{medline-title
* {{medline-title
|title=Nanocarrier-Mediated Chemo-Immunotherapy Arrested Cancer Progression and Induced Tumor Dormancy in Desmoplastic Melanoma.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=28.08.2018
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30016071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115293
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
==UBE3A==
==MAF==


* {{medline-title
* {{medline-title
|title=Delayed loss of [[UBE3A]] reduces the expression of Angelman syndrome-associated phenotypes.
|title=Biocatalytic Degradation Efficiency of Postconsumer Polyethylene Terephthalate Packaging Determined by Their Polymer Microstructures.
|date=2019
|date=17.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31143434
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31380212
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532248
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662049
}}
}}
==SEMA3A==
==MAF1==


* {{medline-title
* {{medline-title
|title=Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging.
|title=Beyond regulation of pol III: Role of [[MAF1]] in growth, metabolism, aging and cancer.
|date=05.03.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661929
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29407795
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2018.12.021
|full-text-url=https://sci-hub.do/10.1016/j.bbagrm.2018.01.019
}}
}}
==HRH4==
==MAFB==


* {{medline-title
* {{medline-title
|title=Histamime Receptor H4 as a New Therapeutic Target for Age-related Macular Degeneration.
|title=Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy.
|date=11.2016
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30074739
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30605403
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485685
}}
}}
==VPREB3==
==MAL==


* {{medline-title
* {{medline-title
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|title=Daylight photodynamic therapy versus cryosurgery for the treatment and prophylaxis of actinic keratoses of the face - protocol of a multicenter, prospective, randomized, controlled, two-armed study.
|date=19.01.2019
|date=25.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29070025
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657041
}}
}}
==FRG2==
==MAOA==


* {{medline-title
* {{medline-title
|title=Intergenerational response of steroidogenesis-related genes to maternal malnutrition.
|title=Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing.
|date=10.2019
|date=05.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789120
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28953873
|full-text-url=https://sci-hub.do/10.1017/S2040174419000060
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149
}}
}}
==CYP19A1==
==MAP1A==


* {{medline-title
* {{medline-title
|title=Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=06.2019
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30923019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2019.03.016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==AANAT==
==MAP1B==


* {{medline-title
* {{medline-title
|title=Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=01.06.2019
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890428
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993622
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==ALKBH1==
==MAP2K3==


* {{medline-title
* {{medline-title
|title=ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans.
|title=Associations of [i][[MAP2K3]][/i] Gene Variants With Superior Memory in SuperAgers.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30338756
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29896098
 
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987172
}}
}}
==NLRC5==
==MAP3K5==


* {{medline-title
* {{medline-title
|title=Methylation of the genes ROD1, [[NLRC5]], and HKR1 is associated with aging in Hainan centenarians.
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|date=02.02.2018
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29394898
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797414
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
}}
}}
==CD2AP==
==MAP4K3==


* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=[[MAP4K3]]/GLK in autoimmune disease, cancer and aging.
|date=28.03.2018
|date=22.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31640697
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806545
}}
}}
==KIF1B==
==MAPK10==


* {{medline-title
* {{medline-title
|title=[[BDNF]] trafficking and signaling impairment during early neurodegeneration is prevented by moderate physical activity.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=12.2016
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30135925
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084862
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==CFB==
==MAPK11==


* {{medline-title
* {{medline-title
|title=The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye.
|title=lncRNA ENSMUST00000134285 Increases [[MAPK11]] Activity, Regulating Aging-Related Myocardial Apoptosis.
|date=13.06.2018
|date=09.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29905533
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415197
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230
|full-text-url=https://sci-hub.do/10.1093/gerona/gly020
}}
}}
==ID2==
==MAPK13==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=10.2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==ICE1==
==MAPK8==


* {{medline-title
* {{medline-title
|title=ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=19.02.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31783407
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031079
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
==CPT2==
==MARCKS==


* {{medline-title
* {{medline-title
|title=The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats.
|title=Ser46-Phosphorylated [[MARCKS]] Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology.
|date=09.2020
|date=07-08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32729662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225354
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140116
}}
}}
==CAMSAP1==
==MARCKSL1==


* {{medline-title
* {{medline-title
|title=Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex.
|title=[[MARCKSL1]] Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors.
|date=2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30210331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580842
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952351
}}
}}
==SCX==
==MARK1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=15.11.2018
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==SKI==
==MAS1==


* {{medline-title
* {{medline-title
|title=Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells.
|title=AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation.
|date=04.2019
|date=17.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29700792
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667931
|full-text-url=https://sci-hub.do/10.1007/s11684-017-0586-8
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940107
}}
}}
==NKIRAS2==
==MATN3==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis.
|date=11.2017
|date=19.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31963938
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013758
}}
}}
==XG==
==MAVS==


* {{medline-title
* {{medline-title
|title=The effect of administration media on palatability and ease of swallowing of multiparticulate formulations.
|title=Spontaneous activation of a [[MAVS]]-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes.
|date=15.11.2018
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30170024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822807
|full-text-url=https://sci-hub.do/10.1016/j.ijpharm.2018.08.021
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600710
}}
}}
==S100A13==
==MAX==


* {{medline-title
* {{medline-title
|title=[[S100A13]] promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α.
|title=Validation of the MedUseQ: A Self-Administered Screener for Older Adults to Assess Medication Use Problems.
|date=23.01.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30670674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656678
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366962
|full-text-url=https://sci-hub.do/10.1177/0897190018766789
}}
}}
==MYCNOS==
==MBD2==


* {{medline-title
* {{medline-title
|title=Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis.
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|date=26.01.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831999
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
}}
}}
==TCF7==
==MC1R==


* {{medline-title
* {{medline-title
|title=Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice.
|title=In vitro behavior and UV response of melanocytes derived from carriers of [[[[CDKN2A]]]] mutations and [[MC1R]] variants.
|date=04.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29206307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30117292
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925424
|full-text-url=https://sci-hub.do/10.1111/pcmr.12732
}}
}}
==DCTN6==
==MCAT==


* {{medline-title
* {{medline-title
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|title=Small molecules as therapeutic drugs for Alzheimer's disease.
|date=09.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30877034
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510253
}}
}}
==HDC==
==MCF2L==


* {{medline-title
* {{medline-title
|title=Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=07.05.2020
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2020.02.092
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==CCL28==
==MCM3==


* {{medline-title
* {{medline-title
|title=Age-related chemokine alterations affect IgA secretion and gut immunity in female mice.
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=10.2020
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32277312
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09877-9
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
}}
==GPR19==
==MCM4==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=15.11.2018
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
}}
==WNT10A==
==MCM5==


* {{medline-title
* {{medline-title
|title=Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development.
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=01.04.2020
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31964233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://sci-hub.do/10.1089/scd.2019.0260
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
}}
==TRBV19==
==MCM6==


* {{medline-title
* {{medline-title
|title=Perturbed CD8  T cell immunity across universal influenza epitopes in the elderly.
|title=Changes in [[MCM2]]-7 proteins at senescence.
|date=02.2018
|date=27.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928269
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31092751
|full-text-url=https://sci-hub.do/10.1189/jlb.5MA0517-207R
|full-text-url=https://sci-hub.do/10.1266/ggs.18-00062
}}
}}
==NPRL3==
==MCM8==


* {{medline-title
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|date=05.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
}}
}}
==DCLRE1C==
==MCM9==


* {{medline-title
* {{medline-title
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|title=MCM8- and [[MCM9]] Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors.
|date=06.2019
|date=10.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31509747
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.07.095
}}
}}
==ADNP==
==MCUR1==


* {{medline-title
* {{medline-title
|title=[[ADNP]] differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging.
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|date=06.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264075
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702513
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
}}
}}
==LIFR==
==MDK==


* {{medline-title
* {{medline-title
|title=Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats.
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=15.03.2019
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30445025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
==COQ5==
==MDN1==


* {{medline-title
* {{medline-title
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=18.09.2018
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
==MICU1==
==ME1==


* {{medline-title
* {{medline-title
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|title=NADP-MALIC ENZYME 1 Affects Germination after Seed Storage in Arabidopsis thaliana.
|date=09.2019
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30388244
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
|full-text-url=https://sci-hub.do/10.1093/pcp/pcy213
}}
}}
==SRPK1==
==MECOM==


* {{medline-title
* {{medline-title
|title=[Age-related changes in the content of serine-arginine protein kinase 1 ([[SRPK1]]) in human dermis.]
|title=Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.
|date=2017
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322729
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603369
 
|full-text-url=https://sci-hub.do/10.1111/jgh.14149
}}
}}
==PCDHGA3==
==MED25==


* {{medline-title
* {{medline-title
|title=DNA methylation associated with healthy aging of elderly twins.
|title=The [i]HAC1[/i] histone acetyltransferase promotes leaf senescence and regulates the expression of [i]ERF022[/i].
|date=12.2018
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30136078
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468026
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710649
}}
}}
==RPTOR==
==MEFV==


* {{medline-title
* {{medline-title
|title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107.
|title=The grandfather's fever.
|date=08.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31401792
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016
|full-text-url=https://sci-hub.do/10.1007/s10067-019-04741-9
}}
}}
==MYH10==
==MEOX2==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=Reduced expression of microRNA-130a promotes endothelial cell senescence and age-dependent impairment of neovascularization.
|date=10.2019
|date=26.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32457253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346016
}}
}}
==DMPK==
==MERTK==


* {{medline-title
* {{medline-title
|title=Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=19.04.2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30878478
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.jmb.2019.03.003
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==IFITM3==
==MEST==


* {{medline-title
* {{medline-title
|title=Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein [[IFITM3]].
|title=Improving specific autobiographical memory in older adults: impacts on mood, social problem solving, and functional limitations.
|date=25.06.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825508
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613042
|full-text-url=https://sci-hub.do/10.1080/13825585.2017.1365815
}}
}}
==TDG==
==MFN1==


* {{medline-title
* {{medline-title
|title=lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/[[TDG]] axis.
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.
|date=09.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282110
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714223
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
}}
}}
==PMS2==
==MFSD2A==


* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease.
|date=25.02.2019
|date=20.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31861865
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981746
}}
}}
==JAGN1==
==MGRN1==


* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=Chronic and age-dependent effects of the spongiform neurodegeneration-associated [[MGRN1]] E3 ubiquitin ligase on mitochondrial homeostasis.
|date=13.11.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31089807
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639055
}}
}}
==MDN1==
==MIB1==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=Immunohistochemical detection of senescence markers in human sarcomas.
|date=16.08.2019
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31899047
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://sci-hub.do/10.1016/j.prp.2019.152800
}}
}}
==MARCKSL1==
==MICA==


* {{medline-title
* {{medline-title
|title=[[MARCKSL1]] Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors.
|title=Derivation and Validation of a Geriatric-Sensitive Perioperative Cardiac Risk Index.
|date=04.2018
|date=16.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580842
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952351
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721761
}}
}}
==CCR3==
==MICB==


* {{medline-title
* {{medline-title
|title=Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro.
|title=Genetic associations with age of menopause in familial longevity.
|date=04.02.2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32033185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036885
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==CD209==
==MICU1==


* {{medline-title
* {{medline-title
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|date=03.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
}}
}}
==IL22==
==MLH3==


* {{medline-title
* {{medline-title
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|title=Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes.
|date=07.2019
|date=19.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28942922
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679441
}}
}}
==RICTOR==
==MMP12==


* {{medline-title
* {{medline-title
|title=Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase.
|title=Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for [[MMP12]] through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice.
|date=11.2019
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31476350
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28814604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059097
|full-text-url=https://sci-hub.do/10.4049/jimmunol.1601696
}}
}}
==CDR1==
==MMP14==


* {{medline-title
* {{medline-title
|title=Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires.
|title=Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells.
|date=2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29403498
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786517
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755030
}}
}}
==PES1==
==MMP7==


* {{medline-title
* {{medline-title
|title=Transcription factor RD26 is a key regulator of metabolic reprogramming during dark-induced senescence.
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|date=06.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659022
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|full-text-url=https://sci-hub.do/10.1111/nph.15127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
}}
}}
==ATF7==
==MORF4L1==


* {{medline-title
* {{medline-title
|title=Stress-induced and [[ATF7]]-dependent epigenetic change influences cellular senescence.
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|date=09.2019
|date=20.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31294895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|full-text-url=https://sci-hub.do/10.1111/gtc.12713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
}}
}}
==NDUFAB1==
==MPHOSPH6==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length.
|date=02.2018
|date=05.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32109421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058826
}}
}}
==AQP5==
==MPL==


* {{medline-title
* {{medline-title
|title=Submandibular gland-specific inflammaging-induced hyposalivation in the male senescence-accelerated mouse prone -1 line (SAM-P1).
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender.
|date=08.2019
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30684147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09797-3
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0
}}
}}
==PER3==
==MPST==


* {{medline-title
* {{medline-title
|title=Effects of [[PER3]] clock gene polymorphisms on aging-related changes of the cerebral cortex.
|title=Methionine restriction leads to hyperhomocysteinemia and alters hepatic H S production capacity in Fischer-344 rats.
|date=03.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28900721
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30367932
|full-text-url=https://sci-hub.do/10.1007/s00429-017-1513-0
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.10.004
}}
}}
==TSPYL5==
==MR1==


* {{medline-title
* {{medline-title
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers.
|date=03.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826
}}
}}
==CDC20==
==MRO==


* {{medline-title
* {{medline-title
|title=Premature aging syndrome showing random chromosome number instabilities with [[CDC20]] mutation.
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats].
|date=11.2020
|date=08.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33094908
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681047
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110
}}
}}
==DIP2A==
==MRPS5==


* {{medline-title
* {{medline-title
|title=Blocking the [[FSTL1]]-[[DIP2A]] Axis Improves Anti-tumor Immunity.
|title=Mutant [[MRPS5]] affects mitoribosomal accuracy and confers stress-related behavioral alterations.
|date=14.08.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30110636
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30237157
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.07.043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216279
}}
}}
==ME1==
==MRTFA==


* {{medline-title
* {{medline-title
|title=NADP-MALIC ENZYME 1 Affects Germination after Seed Storage in Arabidopsis thaliana.
|title=Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse.
|date=01.02.2019
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30388244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30422822
|full-text-url=https://sci-hub.do/10.1093/pcp/pcy213
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355303
}}
}}
==UCHL3==
==MS4A1==


* {{medline-title
* {{medline-title
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|date=12.06.2018
|date=19.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
}}
}}
==HSD17B4==
==MS4A4E==


* {{medline-title
* {{medline-title
|title=Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein-2 deficiency.
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=09.2018
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29341299
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://sci-hub.do/10.1111/bpa.12586
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
==CCL18==
==MS4A6A==


* {{medline-title
* {{medline-title
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|date=07.2019
|date=28.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
}}
}}
==OLFML3==
==MSH2==


* {{medline-title
* {{medline-title
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=02.2019
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
}}
==DOCK11==
==MSH3==


* {{medline-title
* {{medline-title
|title=[Immunosenescence: The Forefront of Infection and Trophic Control].
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=2020
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32115558
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00193-3
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
}}
==NMS==
==MSH6==


* {{medline-title
* {{medline-title
|title=Uncontrolled Diabetes as an Associated Factor with Dynapenia in Adults Aged 50 Years or Older: Sex Differences.
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=22.05.2020
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665234
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243578
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
}}
==AKAP17A==
==MSRA==


* {{medline-title
* {{medline-title
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|title=Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis.
|date=10.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30456853
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351846
}}
}}
==XRCC4==
==MST1==


* {{medline-title
* {{medline-title
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.
|title=[Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice].
|date=2018
|date=25.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31218331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081
 
}}
}}
==DGAT2==
==MTRR==


* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults.
|date=08.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31208817
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2019.05.013
}}
}}
==RBM38==
==MUC5AC==


* {{medline-title
* {{medline-title
|title=Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating [[PTEN]].
|title=InflammAging at Ocular Surface: Clinical and Biomolecular Analyses in Healthy Volunteers.
|date=15.03.2018
|date=01.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29330147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31022299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340497
|full-text-url=https://sci-hub.do/10.1167/iovs.18-25822
}}
}}
==MCM9==
==MUC7==


* {{medline-title
* {{medline-title
|title=MCM8- and [[MCM9]] Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors.
|title=Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model.
|date=10.09.2019
|date=24.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31509747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31554163
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.07.095
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835954
}}
}}
==IGFBP6==
==MUL1==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models.
|date=02.2018
|date=28.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415
}}
}}
==AQP2==
==MUS81==


* {{medline-title
* {{medline-title
|title=A bell-shaped pattern of urinary aquaporin-2-bearing extracellular vesicle release in an experimental model of nephronophthisis.
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|date=05.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074077
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
}}
}}
==CYB5R3==
==MX1==


* {{medline-title
* {{medline-title
|title=Overexpression of [[CYB5R3]] and [[NQO1]], two NAD  -producing enzymes, mimics aspects of caloric restriction.
|title=Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection.
|date=08.2018
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29706024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878083
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052403
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230210
}}
}}
==XDH==
==MYCN==


* {{medline-title
* {{medline-title
|title=Enhancing xanthine dehydrogenase activity is an effective way to delay leaf senescence and increase rice yield.
|title=Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells.
|date=11.03.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065298
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947931
}}
}}
==FEZ1==
==MYCNOS==


* {{medline-title
* {{medline-title
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|title=Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis.
|date=19.09.2017
|date=26.01.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29657277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831999
}}
}}
==CD82==
==MYH10==


* {{medline-title
* {{medline-title
|title=Cell-surface phenotyping identifies [[CD36]] and CD97 as novel markers of fibroblast quiescence in lung fibrosis.
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|date=01.11.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29952218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|full-text-url=https://sci-hub.do/10.1152/ajplung.00439.2017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
}}
}}
==IHH==
==MYLPF==


* {{medline-title
* {{medline-title
|title=Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway.
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle.
|date=01.04.2020
|date=15.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32235006
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185126
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004
}}
}}
==UBC==
==MYO1F==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
}}
}}
==SMARCA5==
==MYOC==


* {{medline-title
* {{medline-title
|title=The epigenetic regulator [[SIRT7]] guards against mammalian cellular senescence induced by ribosomal DNA instability.
|title=Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
|date=13.07.2018
|date=28.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389787
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052228
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311499
}}
}}
==HCN4==
==MYOF==


* {{medline-title
* {{medline-title
|title=Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels.
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|date=05.2018
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29288034
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934612
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
}}
}}
==LAT==
==MYSM1==


* {{medline-title
* {{medline-title
|title=Is the combined auriculotherapy approach superior to magneto-auriculotherapy alone in aging males with lower urinary tract symptoms? A randomized controlled trial.
|title=[[MYSM1]] Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan.
|date=16.01.2019
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30651007
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33240758
|full-text-url=https://sci-hub.do/10.1080/13685538.2018.1542673
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675055
}}
}}
==VGLL4==
==MYT1==


* {{medline-title
* {{medline-title
|title=The lncRNA MEG3/miR-16-5p/[[VGLL4]] regulatory axis is involved in etoposide-induced senescence of tumor cells.
|title=ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the [[MYT1]]-Egln3-Sirt1 Axis.
|date=03.11.2020
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33141998
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33038325
|full-text-url=https://sci-hub.do/10.1002/jgm.3291
|full-text-url=https://sci-hub.do/10.1016/j.ymthe.2020.09.037
}}
}}
==PDE2A==
==NACA==


* {{medline-title
* {{medline-title
|title=TAK-915, a phosphodiesterase 2A inhibitor, ameliorates the cognitive impairment associated with aging in rodent models.
|title=Age and Sex Are Strongly Correlated to the Rate and Type of Mountain Injuries Requiring Search and Rescue Missions.
|date=30.12.2019
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521738
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31699646
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2019.112192
|full-text-url=https://sci-hub.do/10.1016/j.wem.2019.06.016
}}
}}
==PLCG2==
==NAIP==


* {{medline-title
* {{medline-title
|title=A nonsynonymous mutation in [[PLCG2]] reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
|title=Protective effect of xanthohumol against age-related brain damage.
|date=08.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31131421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28950154
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501
|full-text-url=https://sci-hub.do/10.1016/j.jnutbio.2017.07.011
}}
}}
==GPR37L1==
==NBN==


* {{medline-title
* {{medline-title
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=08.2018
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==CSF3R==
==NBR1==


* {{medline-title
* {{medline-title
|title=Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
|title=Nrf2 mediates the expression of [[BAG3]] and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
|date=13.11.2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30040071
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29304346
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256814
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049
}}
}}
==APOC1==
==NCK2==


* {{medline-title
* {{medline-title
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|title=Genetic associations with age of menopause in familial longevity.
|date=08.10.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==CCL13==
==NCOR2==


* {{medline-title
* {{medline-title
|title=Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=07.2019
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30685456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://sci-hub.do/10.1016/j.jaci.2019.01.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==PLXNA4==
==NDN==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging.
|date=15.11.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087674
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066563
}}
}}
==KLHL22==
==NDRG1==


* {{medline-title
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|title=Cx43 phosphorylation-mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein [[NDRG1]].
|date=05.2018
|date=02.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189653
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682735
}}
}}
==CES1==
==NDRG2==


* {{medline-title
* {{medline-title
|title=[Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog].
|title=[[NDRG2]] Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain.
|date=2019
|date=04.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31061351
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31947996
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00228
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982267
}}
}}
==GSTM2==
==NDUFAB1==


* {{medline-title
* {{medline-title
|title=Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=07.07.2020
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32574561
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7342013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==KCNK2==
==NDUFS1==


* {{medline-title
* {{medline-title
|title=Brain age prediction using deep learning uncovers associated sequence variants.
|title=Mapping the protein phosphorylation sites in human mitochondrial complex I (NADH: Ubiquinone oxidoreductase): A bioinformatics study with implications for brain aging and neurodegeneration.
|date=27.11.2019
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31776335
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29499254
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881321
|full-text-url=https://sci-hub.do/10.1016/j.jchemneu.2018.02.004
}}
}}
==ETV5==
==NDUFS3==


* {{medline-title
* {{medline-title
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
|title=Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10).
|date=06.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477336
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.025
}}
}}
==TLR5==
==NDUFS8==


* {{medline-title
* {{medline-title
|title=Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.
|title=Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity.
|date=08.2018
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30089902
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32773682
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0395-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494633
}}
}}
==XPC==
==NDUFV2==


* {{medline-title
* {{medline-title
|title=MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene [[XPC]] in Age-related Cataract.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=12.10.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30315181
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185952
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==HS2ST1==
==NEFM==


* {{medline-title
* {{medline-title
|title=Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity.
|title=Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age.
|date=31.01.2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31940721
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30927131
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6999708
|full-text-url=https://sci-hub.do/10.1007/s10735-019-09820-4
}}
}}
==IFITM1==
==NEIL1==


* {{medline-title
* {{medline-title
|title=Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection.
|title=[[NEIL1]] stimulates neurogenesis and suppresses neuroinflammation after stress.
|date=10.11.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29878083
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175982
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526462
}}
}}
==PTP4A3==
==NEIL3==


* {{medline-title
* {{medline-title
|title=Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease.
|title=Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin.
|date=05.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32402127
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31167196
|full-text-url=https://sci-hub.do/10.1002/adbi.202000044
|full-text-url=https://sci-hub.do/10.1159/000500091
}}
}}
==PDE4C==
==NEK2==


* {{medline-title
* {{medline-title
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|title=Upregulation of [[FOXM1]] leads to diminished drug sensitivity in myeloma.
|date=04.2018
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463534
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249818
}}
}}
==ARSA==
==NEO1==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Neogenin-1 distinguishes between myeloid-biased and balanced [i]Hoxb5[/i]   mouse long-term hematopoietic stem cells.
|date=06.2018
|date=10.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754028
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911217
}}
}}
==PRKAA1==
==NFATC1==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
|date=02.2019
|date=02.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654
}}
}}
==CACNA1S==
==NFKB1==


* {{medline-title
* {{medline-title
|title=Increased calcium channel in the lamina propria of aging rat.
|title=[[NFKB1]] gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.
|date=31.10.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31682233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32002656
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834399
|full-text-url=https://sci-hub.do/10.1007/s00277-020-03935-5
}}
}}
==HOXB7==
==NGFR==


* {{medline-title
* {{medline-title
|title=Impact of [[HOXB7]] overexpression on human adipose-derived mesenchymal progenitors.
|title=Evidence for changing nerve growth factor signalling mechanisms during development, maturation and ageing in the rat molar pulp.
|date=19.03.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30890185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30099752
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423808
|full-text-url=https://sci-hub.do/10.1111/iej.12997
}}
}}
==CCL19==
==NKAP==


* {{medline-title
* {{medline-title
|title=Age-Related Gliosis Promotes Central Nervous System Lymphoma through [[CCL19]]-Mediated Tumor Cell Retention.
|title=[[NKAP]] Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors.
|date=16.09.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31526758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31632967
|full-text-url=https://sci-hub.do/10.1016/j.ccell.2019.08.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783958
}}
}}
==LAG3==
==NKIRAS2==


* {{medline-title
* {{medline-title
|title=T Cell Transcriptional Profiling and Immunophenotyping Uncover [[LAG3]] as a Potential Significant Target of Immune Modulation in Multiple Myeloma.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=01.2020
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31445183
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952061
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==SFRP2==
==NKX2-5==


* {{medline-title
* {{medline-title
|title=[Role and alterations of DNA methylation during the aging and cancer].
|title=Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart.
|date=01.2018
|date=07.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30663680
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207148
}}
}}
==SYNE1==
==NKX6-1==


* {{medline-title
* {{medline-title
|title=Nesprin-1 impact on tumorigenic cell phenotypes.
|title=The dynamic methylome of islets in health and disease.
|date=02.2020
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31741263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500828
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05184-w
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768570
}}
}}
==BACH2==
==NLRC5==


* {{medline-title
* {{medline-title
|title=Age-related changes in the [[BACH2]] and [[PRDM1]] genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.
|title=Methylation of the genes ROD1, [[NLRC5]], and HKR1 is associated with aging in Hainan centenarians.
|date=17.01.2019
|date=02.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654767
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29394898
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797414
}}
}}
==HIRA==
==NLRP1==


* {{medline-title
* {{medline-title
|title=Pak2 kinase promotes cellular senescence and organismal aging.
|title=NADPH oxidase 2-mediated [[NLRP1]] inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro.
|date=02.07.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31209047
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30677569
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613284
|full-text-url=https://sci-hub.do/10.1016/j.intimp.2019.01.025
}}
}}
==CXCR1==
==NLRP12==


* {{medline-title
* {{medline-title
|title=Harmful neutrophil subsets in patients with ischemic stroke: Association with disease severity.
|title=Persistent DNA damage-induced [[NLRP12]] improves hematopoietic stem cell function.
|date=07.2019
|date=21.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31355307
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434992
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259522
}}
}}
==HIF3A==
==NLRP6==


* {{medline-title
* {{medline-title
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|title=LRP6 targeting suppresses gastric tumorigenesis via P14 -Mdm2-P53-dependent cellular senescence.
|date=07.2018
|date=19.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29340077
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762345
}}
}}
==GPR101==
==NLRX1==


* {{medline-title
* {{medline-title
|title=Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent.
|title=NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells.
|date=2017
|date=26.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29482578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828065
}}
}}
==HDAC11==
==NMI==


* {{medline-title
* {{medline-title
|title=Disruption to schizophrenia-associated gene Fez1 in the hippocampus of [[HDAC11]] knockout mice.
|title=Age-Dependent Control of Shoulder Muscles During a Reach-and-Lift Task.
|date=19.09.2017
|date=10.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31825888
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605701
|full-text-url=https://sci-hub.do/10.1123/japa.2019-0055
}}
}}
==SRI==
==NMRK2==


* {{medline-title
* {{medline-title
|title=The Role of Aging, Drug Dependence, and Hepatitis C Comorbidity in Alcoholism Cortical Compromise.
|title=Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training.
|date=01.05.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29541774
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283350
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875381
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156423
}}
}}
==GRM2==
==NMS==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=Uncontrolled Diabetes as an Associated Factor with Dynapenia in Adults Aged 50 Years or Older: Sex Differences.
|date=11.2017
|date=22.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31665234
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243578
}}
}}
==SRM==
==NMUR1==


* {{medline-title
* {{medline-title
|title=[Geriatric specificities of localized renal cell carcinoma].
|title=[Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules].
|date=11.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771769
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31685733
|full-text-url=https://sci-hub.do/10.1016/j.purol.2019.08.281
|full-text-url=https://sci-hub.do/10.1248/yakushi.19-00149
}}
}}
==SLC41A1==
==NOA1==


* {{medline-title
* {{medline-title
|title=Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis.
|title=The dependence of leaf senescence on the balance between 1-aminocyclopropane-1-carboxylate acid synthase 1 (ACS1)-catalysed ACC generation and nitric oxide-associated 1 (NOS1)-dependent NO accumulation in Arabidopsis.
|date=08.05.2019
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31076559
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30734982
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535063
|full-text-url=https://sci-hub.do/10.1111/plb.12970
}}
}}
==SV2C==
==NOBOX==


* {{medline-title
* {{medline-title
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|date=10.2018
|date=18.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
}}
}}
==CCND1==
==NOL12==


* {{medline-title
* {{medline-title
|title=Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells.
|title=[[NOL12]] Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
|date=09.2020
|date=15.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32592933
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988155
|full-text-url=https://sci-hub.do/10.1016/j.archoralbio.2020.104819
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549468
}}
}}
==RAB1B==
==NOTCH4==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH.
|date=2019
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595581
}}
}}
==CD59==
==NPAS2==


* {{medline-title
* {{medline-title
|title=Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria.
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|date=2019
|date=21.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31156458
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529780
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
}}
}}
==SLC1A5==
==NPBWR1==


* {{medline-title
* {{medline-title
|title=[[SLC1A5]] glutamine transporter is a target of [[MYC]] and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=06.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909319
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516164
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==TP53RK==
==NPC2==


* {{medline-title
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|title=Attenuation of the Niemann-Pick type [[C2]] disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2.
|date=11.04.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29655638
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2018.04.001
}}
}}
==IAPP==
==NPM1==


* {{medline-title
* {{medline-title
|title=Protein aggregates and proteostasis in aging: Amylin and β-cell function.
|title=Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats.
|date=01.2019
|date=29.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29580826
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31784606
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.03.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884578
}}
}}
==PAX8==
==NPRL2==


* {{medline-title
* {{medline-title
|title=Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging.
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|date=13.09.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31518338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781991
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
}}
}}
==GPR173==
==NPRL3==


* {{medline-title
* {{medline-title
|title=Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent.
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|date=2017
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163355
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663685
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
}}
}}
==TES==
==NPW==


* {{medline-title
* {{medline-title
|title=The Effects of Electrical Stimulation Pulse Duration on Lingual Palatal Pressure Measures During Swallowing in Healthy Older Adults.
|title=Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study.
|date=08.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820657
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32309980
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456514
|full-text-url=https://sci-hub.do/10.1037/pag0000468
}}
}}
==NBN==
==NR3C1==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=Glucocorticoid receptor ([[NR3C1]]) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians.
|date=15.11.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30553025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.12.006
}}
}}
==IRF5==
==NRARP==


* {{medline-title
* {{medline-title
|title=Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice.
|title=Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing [[NRARP]].
|date=11.2017
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28905935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30274778
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672072
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.09.045
}}
}}
==NOTCH4==
==NRL==


* {{medline-title
* {{medline-title
|title=Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH.
|title=Development of a cyclophosphamide stress test to predict resilience to aging in mice.
|date=11.2020
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31920157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32613492
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7595581
|full-text-url=https://sci-hub.do/10.1007/s11357-020-00222-z
}}
}}
==BMPR1B==
==NRM==


* {{medline-title
* {{medline-title
|title=Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes.
|title=Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation.
|date=12.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30503129
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31445185
|full-text-url=https://sci-hub.do/10.1016/j.fertnstert.2018.08.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192097
}}
}}
==IL9==
==NRXN3==


* {{medline-title
* {{medline-title
|title=Transcription factor networks in aged naïve [[CD4]] T cells bias lineage differentiation.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=08.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31264370
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612640
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==GSTZ1==
==NSF==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Effects of air pollution on children from a socioecological perspective.
|date=12.2018
|date=15.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31727016
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857293
}}
}}
==IFI27==
==NT5E==


* {{medline-title
* {{medline-title
|title=Ultraviolet B irradiation-induced keratinocyte senescence and impaired development of 3D epidermal reconstruct.
|title=The [[NT5E]] gene variant strongly affects the degradation rate of inosine 5'-monophosphate under postmortem conditions in Japanese Black beef.
|date=01.06.2021
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33151171
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31401370
|full-text-url=https://sci-hub.do/10.2478/acph-2021-0011
|full-text-url=https://sci-hub.do/10.1016/j.meatsci.2019.107893
}}
}}
==ADRA2B==
==NTHL1==


* {{medline-title
* {{medline-title
|title=Aging and the Combined effects of [[ADRA2B]] and CB1 deletions on Affective Working Memory.
|title=Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals.
|date=11.03.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30858399
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31970600
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205949
}}
}}
==NCOR2==
==NTN4==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=[[EGF]]/[[EGF]]R upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence.
|date=25.07.2018
|date=04.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30514230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280426
}}
}}
==ASPA==
==NUCB2==


* {{medline-title
* {{medline-title
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|title=Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise Killifish.
|date=04.2018
|date=31.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31906085
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019235
}}
}}
==SMPD1==
==NUPR1==


* {{medline-title
* {{medline-title
|title=Alterations in Lipid Profile of the Aging Kidney Identified by MALDI Imaging Mass Spectrometry.
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells.
|date=05.07.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31244212
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00108
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327
}}
}}
==GPX3==
==OCLN==


* {{medline-title
* {{medline-title
|title=Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract.
|title=Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats.
|date=2019
|date=17.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31814699
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857780
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b02567
}}
}}
==NDN==
==OGA==


* {{medline-title
* {{medline-title
|title=The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging.
|title=NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase.
|date=2018
|date=19.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30087674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31747588
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066563
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2019.10.053
}}
}}
==ADAMTS9==
==OLFML3==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|date=02.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
}}
}}
==PRG4==
==OMD==


* {{medline-title
* {{medline-title
|title=Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis.
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|date=08.02.2018
|date=06.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415892
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821202
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
}}
}}
==PAFAH2==
==OOEP==


* {{medline-title
* {{medline-title
|title=Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs.
|title=Maternal gene [i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes.
|date=03.2019
|date=18.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30521374
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29955025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404557
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085769
}}
}}
==CYP3A5==
==OSGEP==


* {{medline-title
* {{medline-title
|title=Effect of Age and Allele Variants of [[CYP3A5]], [[CYP3A4]], and [[POR]] Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia.
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|date=12.2017
|date=11.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29135906
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|full-text-url=https://sci-hub.do/10.1097/FTD.0000000000000442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
}}
}}
==THEMIS==
==OSM==


* {{medline-title
* {{medline-title
|title=Lifetime benefits of early detection and treatment of diabetic kidney disease.
|title=Age Differences in Sexual Minority Stress and the Importance of Friendship in Later Life.
|date=2019
|date=04.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31150444
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33143546
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544227
|full-text-url=https://sci-hub.do/10.1080/07317115.2020.1836107
}}
}}
==FGF6==
==OTX2==


* {{medline-title
* {{medline-title
|title=Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages.
|title=Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice.
|date=06.02.2019
|date=01.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30727969
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29337233
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819331
}}
}}
==TPP1==
==OXR1==


* {{medline-title
* {{medline-title
|title=FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping.
|title=Oxidation resistance 1 is a novel senolytic target.
|date=03.11.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33086033
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29766639
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2020.10.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052462
}}
}}
==IGSF1==
==P2RY10==


* {{medline-title
* {{medline-title
|title=Age-related gene and miRNA expression changes in airways of healthy individuals.
|title=Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury.
|date=06.03.2019
|date=12.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31189983
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561964
}}
}}
==KDM3A==
==P4HA2==


* {{medline-title
* {{medline-title
|title=[[KDM3A]] and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization.
|title=Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients.
|date=22.11.2019
|date=03.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31704649
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31560770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888768
|full-text-url=https://sci-hub.do/10.1167/iovs.19-27921
}}
}}
==HNF4A==
==P4HA3==


* {{medline-title
* {{medline-title
|title=Hepatocyte Nuclear Factor-4α P2 Promoter Variants Are Associated With the Risk of Metabolic Syndrome and Testosterone Deficiency in Aging Taiwanese Men.
|title=Age-associated genes in human mammary gland drive human breast cancer progression.
|date=11.2018
|date=15.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30415809
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32539762
|full-text-url=https://sci-hub.do/10.1016/j.jsxm.2018.09.012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294649
}}
}}
==KCNC3==
==PABPN1==


* {{medline-title
* {{medline-title
|title=DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird.
|title=Dysfunctional transcripts are formed by alternative polyadenylation in OPMD.
|date=2017
|date=26.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29216256
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29088723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650278
}}
}}
==JARID2==
==PAFAH2==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs.
|date=02.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30521374
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404557
}}
}}
==FAH==
==PARK7==


* {{medline-title
* {{medline-title
|title=Oxaloacetate decarboxylase [[FAH]]D1 - a new regulator of mitochondrial function and senescence.
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=01.2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30055189
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.07.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
}}
==CHRM4==
==PAX1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|date=15.11.2018
|date=26.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
}}
}}
==GEN1==
==PAX5==


* {{medline-title
* {{medline-title
|title=US acculturation and poor sleep among an intergenerational cohort of adult Latinos in Sacramento, California.
|title=Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low [[PAX5]].
|date=01.03.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30544165
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29425852
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424080
|full-text-url=https://sci-hub.do/10.1016/j.clim.2018.02.003
}}
}}
==PDE4B==
==PAX7==


* {{medline-title
* {{medline-title
|title=Phosphodiesterase-4B as a Therapeutic Target for Cognitive Impairment and Obesity-Related Metabolic Diseases.
|title=Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits.
|date=2017
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28956331
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30006671
|full-text-url=https://sci-hub.do/10.1007/978-3-319-58811-7_5
|full-text-url=https://sci-hub.do/10.1007/s00421-018-3943-7
}}
}}
==TYROBP==
==PAX8==


* {{medline-title
* {{medline-title
|title=[[TREM2]] triggers microglial density and age-related neuronal loss.
|title=Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging.
|date=03.2019
|date=13.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548312
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31518338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781991
}}
}}
==PRLR==
==PBX1==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Internalization of the TAT-[[PBX1]] fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence.
|date=15.11.2018
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436118
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1007/s10529-020-02909-x
}}
}}
==ABHD12==
==PCCA==


* {{medline-title
* {{medline-title
|title=Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout [[ABHD12]] Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype.
|title=Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism.
|date=2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31213981
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29159707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555221
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832583
}}
}}
==RPL37==
==PCCB==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism.
|date=2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29159707
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832583
}}
}}
==TRPV5==
==PCDHGA3==


* {{medline-title
* {{medline-title
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|title=DNA methylation associated with healthy aging of elderly twins.
|date=01.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30136078
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294724
}}
}}
==IFT140==
==PCMTD1==


* {{medline-title
* {{medline-title
|title=The Role of [[IFT140]] in Osteogenesis of Adult Mice Long Bone.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=08.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31034313
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669857
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==TCF15==
==PDE10A==


* {{medline-title
* {{medline-title
|title=Loss of Neurogenesis in Aging Hydra.
|title=Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain.
|date=05.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912256
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29175000
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586502
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732030
}}
}}
==ANK3==
==PDE2A==


* {{medline-title
* {{medline-title
|title=Age-related atrophy of cortical thickness and genetic effect of [[ANK3]] gene in first episode MDD patients.
|title=TAK-915, a phosphodiesterase 2A inhibitor, ameliorates the cognitive impairment associated with aging in rodent models.
|date=26.08.2020
|date=30.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32911427
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31521738
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490581
|full-text-url=https://sci-hub.do/10.1016/j.bbr.2019.112192
}}
}}
==MSH6==
==PDE4B==


* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=Phosphodiesterase-4B as a Therapeutic Target for Cognitive Impairment and Obesity-Related Metabolic Diseases.
|date=25.02.2019
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28956331
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://sci-hub.do/10.1007/978-3-319-58811-7_5
}}
}}
==VEGFD==
==PDE4C==


* {{medline-title
* {{medline-title
|title=Single-Arm Resistance Training Study to Determine the Relationship between Training Outcomes and Muscle Growth Factor mRNAs in Older Adults Consuming Numerous Medications and Supplements.
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|date=2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29380855
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|full-text-url=https://sci-hub.do/10.1007/s12603-017-0913-4
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
}}
}}
==LAGE3==
==PDE5A==


* {{medline-title
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|title=Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass.
|date=11.04.2019
|date=23.06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32513693
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321982
}}
}}
==MFN1==
==PDE9A==


* {{medline-title
* {{medline-title
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.
|title=Identification of new [[PDE9A]] isoforms and how their expression and subcellular compartmentalization in the brain change across the life span.
|date=2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29505961
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871571
}}
}}
==ESRG==
==PDF==


* {{medline-title
* {{medline-title
|title=[[MYC]] Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition.
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models.
|date=10.04.2018
|date=28.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29641997
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2018.03.057
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415
}}
}}
==BCL2L1==
==PDGFRB==


* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=A tyrosine kinase-activating variant Asn666Ser in [[PDGFRB]] causes a progeria-like condition in the severe end of Penttinen syndrome.
|date=09.2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30573803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460636
}}
}}
==CDC73==
==PDHB==


* {{medline-title
* {{medline-title
|title=Down-regulation of cancer-associated gene [[CDC73]] contributes to cellular senescence.
|title=Neuron-specific knockdown of Drosophila [[PDHB]] induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting.
|date=23.05.2018
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29621547
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29501567
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.03.228
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2018.02.035
}}
}}
==SIL1==
==PDK4==


* {{medline-title
* {{medline-title
|title=[[SIL1]], the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology.
|title=Putrescine delays postovulatory aging of mouse oocytes by upregulating [[PDK4]] expression and improving mitochondrial activity.
|date=10.05.2018
|date=16.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29666155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30554191
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992605
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326651
}}
}}
==TGFBR1==
==PEBP1==


* {{medline-title
* {{medline-title
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|title=[i]Drosophila[/i] [[PEBP1]] inhibits intestinal stem cell aging via suppression of ERK pathway.
|date=02.2019
|date=06.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29719584
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915051
}}
}}
==MMP7==
==PER3==


* {{medline-title
* {{medline-title
|title=Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9.
|title=Effects of [[PER3]] clock gene polymorphisms on aging-related changes of the cerebral cortex.
|date=2018
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30142172
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28900721
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108478
|full-text-url=https://sci-hub.do/10.1007/s00429-017-1513-0
}}
}}
==CSAD==
==PES1==


* {{medline-title
* {{medline-title
|title=The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway.
|title=Transcription factor RD26 is a key regulator of metabolic reprogramming during dark-induced senescence.
|date=19.09.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659022
|full-text-url=https://sci-hub.do/10.1039/c8fo00740c
|full-text-url=https://sci-hub.do/10.1111/nph.15127
}}
}}
==ERCC6==
==PEX19==


* {{medline-title
* {{medline-title
|title=Two Cockayne Syndrome patients with a novel splice site mutation - clinical and metabolic analyses.
|title=A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells.
|date=10.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29944916
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31854076
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.06.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996960
}}
}}
==DUSP2==
==PEX5==


* {{medline-title
* {{medline-title
|title=Aging Increases Hippocampal [[DUSP2]] by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism.
|title=Aging lowers [[PEX5]] levels in cortical neurons in male and female mouse brains.
|date=2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31293510
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32777345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484460
}}
}}
==FOSL2==
==PF4V1==


* {{medline-title
* {{medline-title
|title=LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis.
|title=Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells.
|date=03.04.2020
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32149459
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30426301
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132339
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3466-x
}}
}}
==DDIT3==
==PFKFB3==


* {{medline-title
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|title=DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system.
|date=2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29101015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871568
}}
}}
==HSPA1L==
==PGAP1==


* {{medline-title
* {{medline-title
|title=Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the [[HSPA1L]]-mitophagy pathway.
|title=Hypoxia-inducible transcription factors, [[HIF1A]] and HIF2A, increase in aging mucosal tissues.
|date=03.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31965731
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338076
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059143
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002220
}}
}}
==RPS6KB1==
==PGK2==


* {{medline-title
* {{medline-title
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|title=Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice.
|date=2018
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31472347
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2019.124650
}}
}}
==DROSHA==
==PGLS==


* {{medline-title
* {{medline-title
|title=Profiling of m6A RNA modifications identified an age-associated regulation of [[AGO2]] mRNA stability.
|title=547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates.
|date=06.2018
|date=28.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573145
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946072
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883628
}}
}}
==FCGR2A==
==PGM1==


* {{medline-title
* {{medline-title
|title=Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells.
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle.
|date=03.08.2019
|date=15.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377747
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710049
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004
}}
}}
==SERPINA1==
==PHB==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
|date=02.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30674441
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412871
}}
}}
==IL2RA==
==PHB2==


* {{medline-title
* {{medline-title
|title=Dynamic demethylation of the [[IL2RA]] promoter during in vitro CD4+ T cell activation in association with [[IL2RA]] expression.
|title=Prohibitin-2 is a novel regulator of p21  induced by depletion of γ-glutamylcyclotransferase.
|date=2018
|date=29.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30096258
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29307834
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140818
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.029
}}
}}
==AGAP2==
==PHGDH==


* {{medline-title
* {{medline-title
|title=Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating [[AGAP2]].
|title=Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase.
|date=05.08.2019
|date=01.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31386624
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31108107
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710058
|full-text-url=https://sci-hub.do/10.1016/j.taap.2019.05.014
}}
}}
==U2AF1==
==PIGR==


* {{medline-title
* {{medline-title
|title=Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=05.03.2020
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32141009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01509-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==SLC19A1==
==PIK3C2A==


* {{medline-title
* {{medline-title
|title=Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=30.03.2018
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29682186
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908287
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
==SAA2==
==PIK3R1==


* {{medline-title
* {{medline-title
|title=Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells.
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|date=2018
|date=08.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884545
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
}}
}}
==COL2A1==
==PIK3R2==


* {{medline-title
* {{medline-title
|title=Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis.
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|date=08.02.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415892
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821202
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
}}
}}
==STC1==
==PIM1==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=[[PIM1]]-catalyzed [[CBX8]] phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast.
|date=02.2018
|date=27.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29763603
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.05.070
}}
}}
==JAM3==
==PIP5K1C==


* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|date=05.2017
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
}}
}}
==NDUFS3==
==PKD1==


* {{medline-title
* {{medline-title
|title=Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10).
|title=The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response.
|date=06.2018
|date=16.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477336
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29420297
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.025
|full-text-url=https://sci-hub.do/10.1242/jcs.207217
}}
}}
==NPRL2==
==PLA2G6==


* {{medline-title
* {{medline-title
|title=[[KLHL22]] activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing.
|title=Mutations in the Drosophila homolog of human [[PLA2G6]] give rise to age-dependent loss of psychomotor activity and neurodegeneration.
|date=05.2018
|date=13.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29440694
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0128-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811537
}}
}}
==SYT1==
==PLA2R1==


* {{medline-title
* {{medline-title
|title=Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins.
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
|date=2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29670520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893842
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922
}}
}}
==SERPINB2==
==PLCG2==


* {{medline-title
* {{medline-title
|title=An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through [[SERPINB2]].
|title=A nonsynonymous mutation in [[PLCG2]] reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
|date=03.07.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080015
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31131421
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501
}}
}}
==EIF2B4==
==PLD3==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=06.2018
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
==LRRC34==
==PLK1==


* {{medline-title
* {{medline-title
|title=The polygenic nature of telomere length and the anti-ageing properties of lithium.
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|date=03.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372618
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
}}
}}
==ACAD9==
==PLN==


* {{medline-title
* {{medline-title
|title=Identification of a novel mitochondrial complex I assembly factor ACDH-12 in Caenorhabditis elegans.
|title=An analysis of the costs of treating aged patients in a large clinical hospital in Poland under the pressure of recent demographic trends.
|date=05.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29540318
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32399116
|full-text-url=https://sci-hub.do/10.1016/j.mito.2018.02.010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212232
}}
}}
==EXOC7==
==PLXNA4==


* {{medline-title
* {{medline-title
|title=[[PTBP1]]-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=09.07.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29990503
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048363
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==VEGFC==
==PMP22==


* {{medline-title
* {{medline-title
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|title=Role of microRNAs in senescence and its contribution to peripheral neuropathy in the arsenic exposed population of West Bengal, India.
|date=02.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29107899
|full-text-url=https://sci-hub.do/10.1111/rda.13091
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2017.09.063
}}
}}
==KCNE4==
==PMS1==


* {{medline-title
* {{medline-title
|title=Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice.
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=29.05.2018
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29844497
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974354
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
}}
==TOMM20==
==PMS2==


* {{medline-title
* {{medline-title
|title=Effect of aging on mitochondria and metabolism of bovine granulosa cells.
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|date=13.09.2020
|date=25.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32921645
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|full-text-url=https://sci-hub.do/10.1262/jrd.2020-071
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
}}
}}
==ENC1==
==POLG2==


* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=An N-Ethyl-N-Nitrosourea (ENU)-Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice.
|date=05.2017
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30395686
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446808
}}
}}
==SSBP2==
==POLL==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Temporal trends in loss of life expectancy after a cancer diagnosis among the Australian population.
|date=10.2019
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32062407
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://sci-hub.do/10.1016/j.canep.2020.101686
}}
}}
==TPX2==
==POLR3A==


* {{medline-title
* {{medline-title
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|title=Nucleolar disruption, activation of P53 and premature senescence in [[POLR3A]]-mutated Wiedemann-Rautenstrauch syndrome fibroblasts.
|date=2018
|date=12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32976914
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111360
}}
}}
==RBMXL1==
==PON1==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview.
|date=16.08.2019
|date=02.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31052559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562914
}}
}}
==BMP7==
==POU3F2==


* {{medline-title
* {{medline-title
|title=Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting [[BMP7]].
|title=[[POU3F2]] participates in cognitive function and adult hippocampal neurogenesis via mammalian-characteristic amino acid repeats.
|date=11.12.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31829291
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782255
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907335
|full-text-url=https://sci-hub.do/10.1111/gbb.12408
}}
}}
==CTSL==
==POU5F1==


* {{medline-title
* {{medline-title
|title=Cathepsin L deficiency results in reactive oxygen species (ROS) accumulation and vascular cells activation.
|title=Cell quality evaluation with gene expression analysis of spheroids (3D) and adherent (2D) adipose stem cells.
|date=12.2017
|date=24.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29041825
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33148459
|full-text-url=https://sci-hub.do/10.1080/10715762.2017.1393665
|full-text-url=https://sci-hub.do/10.1016/j.gene.2020.145269
}}
}}
==GRB2==
==PPA2==


* {{medline-title
* {{medline-title
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice.
|title=Characterization of long living yeast deletion mutants that lack mitochondrial metabolism genes DSS1, [[PPA2]] and AFG3.
|date=21.01.2019
|date=20.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31082499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397
|full-text-url=https://sci-hub.do/10.1016/j.gene.2019.05.001
}}
}}
==PLA2R1==
==PPARG==


* {{medline-title
* {{medline-title
|title=Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes.
|title=The [[PPARG]] Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity.
|date=12.2018
|date=04-06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29116943
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938164
}}
}}
==SF1==
==PPARGC1A==


* {{medline-title
* {{medline-title
|title=Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice.
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|date=15.04.2019
|date=08.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576894
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.12.034
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
}}
}}
==STOML2==
==PPFIA1==


* {{medline-title
* {{medline-title
|title=Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease.
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|date=2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29201274
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672147
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
}}
==IRGM==
==PPM1A==


* {{medline-title
* {{medline-title
|title=[[SIRT6]] histone deacetylase functions as a potential oncogene in human melanoma.
|title=The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1.
|date=09.2017
|date=03.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29234488
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31382626
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724804
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723262
}}
}}
==MORF4L1==
==PPP1R3C==


* {{medline-title
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|date=20.06.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
}}
}}
==WWP1==
==PPP2R1A==


* {{medline-title
* {{medline-title
|title=The ubiquitin ligase [[WWP1]] contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=01.10.2020
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32822210
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717125
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
==THBS1==
==PPP2R3C==


* {{medline-title
* {{medline-title
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|title=The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver.
|date=15.11.2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413667
}}
==CCAR2==
 
* {{medline-title
|title=CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans.
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30003683
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156500
}}
==BRD3==
 
* {{medline-title
|title=Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke.
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30872008
|full-text-url=https://sci-hub.do/10.1016/j.neuint.2019.03.004
}}
}}
==PPP3CB==
==PPP3CB==
Строка 10 799: Строка 10 703:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119720
}}
}}
==GPX7==
==PRDM1==


* {{medline-title
* {{medline-title
|title=Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7.
|title=Age-related changes in the [[BACH2]] and [[PRDM1]] genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.
|date=08.2018
|date=17.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29659168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654767
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337793
}}
}}
==TDP1==
==PRDM16==


* {{medline-title
* {{medline-title
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|title=Assessment of the Aging of the Brown Adipose Tissue by  F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna .
|date=12.06.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079616
}}
}}
==NOL12==
==PRDM8==


* {{medline-title
* {{medline-title
|title=[[NOL12]] Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
|title=[[PRDM8]] reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation.
|date=15.06.2019
|date=20.08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32819411
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439574
}}
}}
==NMRK2==
==PRDX6==


* {{medline-title
* {{medline-title
|title=Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training.
|title=Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30283350
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31417400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156423
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684764
}}
}}
==PIP5K1C==
==PREP==


* {{medline-title
* {{medline-title
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=04.2016
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==DCAF17==
==PRG4==


* {{medline-title
* {{medline-title
|title=Deletion of [[DDB1]]- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice.
|title=Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis.
|date=15.06.2018
|date=08.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29907856
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29415892
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003934
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821202
}}
}}
==WFDC2==
==PRKAA1==


* {{medline-title
* {{medline-title
|title=Differences in biomarkers and molecular pathways according to age for patients with HFrEF.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=01.10.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002110
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://sci-hub.do/10.1093/cvr/cvaa279
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
==DSC1==
==PRKCB==


* {{medline-title
* {{medline-title
|title=HDLs and the pathogenesis of atherosclerosis.
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|date=05.2018
|date=18.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29561322
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|full-text-url=https://sci-hub.do/10.1097/HCO.0000000000000508
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
}}
}}
==ASB7==
==PRKCH==


* {{medline-title
* {{medline-title
|title=[[ASB7]] Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=2020
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33251222
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674779
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==HTRA1==
==PRKDC==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis.
|date=06.2018
|date=29.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31464599
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716822
}}
}}
==KPNA2==
==PRKG1==


* {{medline-title
* {{medline-title
|title=Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-[[CRY1]] Transgenic Mice.
|title=Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis.
|date=2019
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31179341
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507265
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.04.007
}}
}}
==PRDM16==
==PRKN==


* {{medline-title
* {{medline-title
|title=Assessment of the Aging of the Brown Adipose Tissue by  F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna .
|title=[[PRKN]]-regulated mitophagy and cellular senescence during COPD pathogenesis.
|date=2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30116163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30290714
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079616
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351145
}}
}}
==EHF==
==PRLR==


* {{medline-title
* {{medline-title
|title=Extended high frequency hearing and speech perception implications in adults and children.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=11.2020
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32111404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431381
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==SLC26A2==
==PRM1==


* {{medline-title
* {{medline-title
|title=Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis.
|title=Cytological and molecular aspects of the ageing sperm.
|date=01.2020
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31914611
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|full-text-url=https://sci-hub.do/10.1096/fj.201901040RR
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
}}
}}
==SLC2A4==
==PRM2==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Cytological and molecular aspects of the ageing sperm.
|date=02.2019
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
}}
}}
==GGCX==
==PRMT1==


* {{medline-title
* {{medline-title
|title=Multiple Modes of Vitamin K Actions in Aging-Related Musculoskeletal Disorders.
|title=Reactive oxygen species extend insect life span using components of the insulin-signaling pathway.
|date=11.06.2019
|date=12.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31212662
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28847950
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600274
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604040
}}
}}
==OTX2==
==PRMT8==


* {{medline-title
* {{medline-title
|title=Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice.
|title=Arginine Methyltransferase [[PRMT8]] Provides Cellular Stress Tolerance in Aging Motoneurons.
|date=01.03.2018
|date=29.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29337233
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30054395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819331
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113905
}}
}}
==DDI2==
==PRNP==


* {{medline-title
* {{medline-title
|title=Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
|title=Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS.
|date=01.08.2018
|date=06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32516343
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063498
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282622
}}
}}
==NEIL3==
==PRR9==


* {{medline-title
* {{medline-title
|title=Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin.
|title=Circadian control of [i]ORE1[/i] by [[PRR9]] positively regulates leaf senescence in [i]Arabidopsis[/i].
|date=2019
|date=14.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31167196
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30065116
|full-text-url=https://sci-hub.do/10.1159/000500091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099856
}}
}}
==GSTP1==
==PRRX1==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=A [[SIRT1]]-centered circuitry regulates breast cancer stemness and metastasis.
|date=12.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30038266
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283862
}}
}}
==SCN5A==
==PSAP==


* {{medline-title
* {{medline-title
|title=[Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug].
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|date=2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30175758
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00114
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
}}
}}
==FBXO31==
==PSMB8==


* {{medline-title
* {{medline-title
|title=The SCF  ubiquitin ligase complex mediates degradation of the tumor suppressor [[FBXO31]] and thereby prevents premature cellular senescence.
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|date=19.10.2018
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30171069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200945
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
}}
}}
==ENO1==
==PSMD11==


* {{medline-title
* {{medline-title
|title=Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells.
|title=The effect and mechanism of 19S proteasome [[PSMD11]]/Rpn6 subunit in D-Galactose induced mimetic aging models.
|date=2020
|date=01.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32355541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32450067
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191177
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.112093
}}
}}
==FLT3==
==PSMD13==


* {{medline-title
* {{medline-title
|title=Sequential acquisition of mutations in myelodysplastic syndromes.
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=2017
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978821
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://sci-hub.do/10.11406/rinketsu.58.1828
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
==NFKB1==
==PSMD14==


* {{medline-title
* {{medline-title
|title=[[NFKB1]] gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.
|title=Upregulation of deubiquitinase [[PSMD14]] in lung adenocarcinoma (LUAD) and its prognostic significance.
|date=03.2020
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32002656
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32226511
|full-text-url=https://sci-hub.do/10.1007/s00277-020-03935-5
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086243
}}
}}
==DCTN3==
==PSMG1==


* {{medline-title
* {{medline-title
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|date=09.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
}}
}}
==MUS81==
==PTCH1==


* {{medline-title
* {{medline-title
|title=Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling.
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|date=2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30798935
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7043287
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
}}
}}
==DIAPH1==
==PTGS2==


* {{medline-title
* {{medline-title
|title=Diaphanous 1 ([[DIAPH1]]) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease.
|title=Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism.
|date=2018
|date=21.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966194
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31113465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082178
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528237
}}
}}
==ING1==
==PTK2B==


* {{medline-title
* {{medline-title
|title=Impaired DNA demethylation of C/EBP sites causes premature aging.
|title=Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
|date=01.06.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29884649
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30297968
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049513
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354244
}}
}}
==BAZ1A==
==PTK7==


* {{medline-title
* {{medline-title
|title=Chromatin remodeling factor [[BAZ1A]] regulates cellular senescence in both cancer and normal cells.
|title=Innate and adaptive immune dysregulation in critically ill ICU patients.
|date=15.07.2019
|date=05.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31085244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29976949
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.05.023
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033948
}}
}}
==NUPR1==
==PTN==


* {{medline-title
* {{medline-title
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells.
|title=Connecting Metainflammation and Neuroinflammation Through the [[PTN]]-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31031625
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474308
}}
}}
==DNMT3L==
==PTP4A3==


* {{medline-title
* {{medline-title
|title=Transient [[DNMT3L]] Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast.
|title=Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease.
|date=2020
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32195249
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32402127
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064442
|full-text-url=https://sci-hub.do/10.1002/adbi.202000044
}}
}}
==TFPI==
==PTPN1==


* {{medline-title
* {{medline-title
|title=Identification of cardiovascular health gene variants related to longevity in a Chinese population.
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=07.09.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32897244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
}}
==MEST==
==PTPRC==


* {{medline-title
* {{medline-title
|title=Improving specific autobiographical memory in older adults: impacts on mood, social problem solving, and functional limitations.
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|date=09.2018
|date=05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28825508
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|full-text-url=https://sci-hub.do/10.1080/13825585.2017.1365815
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
}}
}}
==CHL1==
==PTPRD==


* {{medline-title
* {{medline-title
|title=Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=07.08.2019
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182634
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687901
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==SFRP1==
==PTPRR==


* {{medline-title
* {{medline-title
|title=[Role and alterations of DNA methylation during the aging and cancer].
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=01.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==MIB1==
==PTTG1==


* {{medline-title
* {{medline-title
|title=Immunohistochemical detection of senescence markers in human sarcomas.
|title=[Down-regulated [[PTTG1]] expression promotes the senescence of human prostate cancer LNCaP-AI].
|date=02.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31899047
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32216239
|full-text-url=https://sci-hub.do/10.1016/j.prp.2019.152800
}}
==KDM6B==


* {{medline-title
|title=Histone demethylase [[KDM6B]] regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells.
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30825201
|full-text-url=https://sci-hub.do/10.1002/jcp.28431
}}
}}
==WNT16==
==PUM1==


* {{medline-title
* {{medline-title
|title=Inducible [i]Wnt16[/i] inactivation: [[WNT16]] regulates cortical bone thickness in adult mice.
|title=Identification of reference genes for RT-qPCR data normalisation in aging studies.
|date=05.2018
|date=27.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29530924
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764958
}}
}}
==MYOC==
==PYCR1==


* {{medline-title
* {{medline-title
|title=Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
|title=A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals [[POSTN]] As a New Element in Proline Metabolic Disorder.
|date=28.12.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389787
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574417
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311499
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284769
}}
}}
==CYP17A1==
==QRFPR==


* {{medline-title
* {{medline-title
|title=Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio).
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|date=03.2018
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29197246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|full-text-url=https://sci-hub.do/10.1016/j.chemosphere.2017.11.128
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
}}
==ADIPOR1==
==RAB1B==


* {{medline-title
* {{medline-title
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
==CTSA==
==RACK1==


* {{medline-title
* {{medline-title
|title=A [[CTSA]]-based consultation service to advance research on special and underserved populations.
|title=Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging.
|date=16.01.2020
|date=05.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33244406
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31636180
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7681147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842600
}}
}}
==MYT1==
==RAD23A==


* {{medline-title
* {{medline-title
|title=ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the [[MYT1]]-Egln3-Sirt1 Axis.
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=01.10.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33038325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://sci-hub.do/10.1016/j.ymthe.2020.09.037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
==WASL==
==RAD50==


* {{medline-title
* {{medline-title
|title=Loss of Wasl improves pancreatic cancer outcome.
|title=Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells.
|date=21.05.2020
|date=01.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434991
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775409
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259520
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172637
}}
}}
==PUM1==
==RAD51B==


* {{medline-title
* {{medline-title
|title=Identification of reference genes for RT-qPCR data normalisation in aging studies.
|title=Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human [[RAD52]] gene in a cardiovascular cohort.
|date=27.09.2019
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31562345
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29024686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764958
|full-text-url=https://sci-hub.do/10.1016/j.mad.2017.10.003
}}
}}
==SPG7==
==RAD51C==


* {{medline-title
* {{medline-title
|title=Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration.
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|date=21.02.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467464
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833341
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
}}
}}
==FOXC1==
==RAD9A==


* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=15.04.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
}}
==MARK1==
==RAF1==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Circular [i]ANRIL[/i] isoforms switch from repressors to activators of [i]p15/CDKN2B[/i] expression during [[RAF1]] oncogene-induced senescence.
|date=04.07.2019
|date=29.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32862732
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1080/15476286.2020.1812910
}}
}}
==EXO1==
==RAG2==


* {{medline-title
* {{medline-title
|title=Polymorphisms of the DNA repair gene [[EXO1]] modulate cognitive aging in old adults in a Taiwanese population.
|title=Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation.
|date=06.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30928815
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793218
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.03.013
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387685
}}
}}
==CYB5A==
==RAI1==


* {{medline-title
* {{medline-title
|title=11-Oxygenated C19 Steroids Do Not Decline With Age in Women.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=01.07.2019
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30753518
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525564
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==RPE65==
==RARB==


* {{medline-title
* {{medline-title
|title=Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells.
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
|date=08.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30091312
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085187
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896
}}
}}
==CRISPLD2==
==RB1==


* {{medline-title
* {{medline-title
|title=A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=20.06.2019
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31219803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==MAPK10==
==RBM25==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif.
|date=15.11.2018
|date=29.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004
}}
}}
==CCNA1==
==RBM3==


* {{medline-title
* {{medline-title
|title=Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.
|title=Infants Uniquely Express High Levels of [[RBM3]] and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain.
|date=02.10.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28920919
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30399610
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617654
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311128
}}
}}
==ZNF521==
==RBM38==


* {{medline-title
* {{medline-title
|title=Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells.
|title=Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating [[PTEN]].
|date=21.06.2019
|date=15.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31227697
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29330147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588633
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340497
}}
}}
==XPO1==
==RBMXL1==


* {{medline-title
* {{medline-title
|title=Nuclear Export Inhibition Enhances HLH-30/[[TFEB]] Activity, Autophagy, and Lifespan.
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|date=15.05.2018
|date=16.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768192
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991088
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
}}
}}
==ITGA5==
==RBP1==


* {{medline-title
* {{medline-title
|title=Kaempferol alleviates the reduction of developmental competence during aging of porcine oocytes.
|title=The SR proteins SF2 and [[RBP1]] regulate triglyceride storage in the fat body of Drosophila.
|date=11.2019
|date=27.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31486245
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277943
|full-text-url=https://sci-hub.do/10.1111/asj.13280
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.151
}}
}}
==IFIH1==
==RBP4==


* {{medline-title
* {{medline-title
|title=Comparative analysis of microbial sensing molecules in mucosal tissues with aging.
|title=[Effects of different intensities exercise combined with resveratrol on [[RBP4]] in aged obese rats].
|date=03.2018
|date=08.05.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29066255
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29926594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821569
|full-text-url=https://sci-hub.do/10.12047/j.cjap.5527.2017.110
}}
}}
==USP28==
==RCAN1==


* {{medline-title
* {{medline-title
|title=Genetic interrogation of replicative senescence uncovers a dual role for [[USP28]] in coordinating the p53 and [[GATA4]] branches of the senescence program.
|title=Mitochondrial dysfunction and endoplasmic reticulum stress involved in oocyte aging: an analysis using single-cell RNA-sequencing of mouse oocytes.
|date=01.10.2017
|date=08.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089421
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31176373
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710139
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556043
}}
}}
==KRT19==
==REC8==


* {{medline-title
* {{medline-title
|title=Characterization of Krt19  allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc.
|title=Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice.
|date=01.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31187500
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667147
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778700
|full-text-url=https://sci-hub.do/10.1007/s11655-018-2835-3
}}
}}
==VPS13D==
==RELA==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|date=04.07.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
}}
}}
==EIF2B3==
==RELB==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=New control of the senescence barrier in breast cancer.
|date=06.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158912
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051141
}}
}}
==SAMD10==
==REV1==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=[[REV1]] inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks.
|date=11.2017
|date=17.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168727
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682577
}}
}}
==MERTK==
==RGS14==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14.
|date=15.11.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29654651
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052469
}}
}}
==GNG4==
==RGS2==


* {{medline-title
* {{medline-title
|title=Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for [[GNG4]] and [[KCNQ2]] Genes.
|title=Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone.
|date=05.2018
|date=01.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29338302
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31043680
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209098
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494869
}}
}}
==TRPM6==
==RHCG==


* {{medline-title
* {{medline-title
|title=Role of kinase-coupled TRP channels in mineral homeostasis.
|title=Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.
|date=04.2018
|date=06.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129644
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170090
|full-text-url=https://sci-hub.do/10.1016/j.pharmthera.2017.11.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594797
}}
}}
==MYLPF==
==RHEBL1==


* {{medline-title
* {{medline-title
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle.
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|date=15.05.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
}}
}}
==G6PC==
==RHOB==


* {{medline-title
* {{medline-title
|title=Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of [[TP53]].
|title=Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes.
|date=11.2018
|date=13.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941676
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31200451
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106910
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627600
}}
}}
==DNAJB9==
==RICTOR==


* {{medline-title
* {{medline-title
|title=[[DNAJB9]] Inhibits p53-Dependent Oncogene-Induced Senescence and Induces Cell Transformation.
|title=Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase.
|date=30.04.2020
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32264658
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31476350
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191047
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059097
}}
}}
==MSRA==
==RIF1==


* {{medline-title
* {{medline-title
|title=Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis.
|title=53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
|date=02.2019
|date=02.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30456853
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653568
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351846
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993210
}}
}}
==DKK2==
==RIMS2==


* {{medline-title
* {{medline-title
|title=Low Serum Levels of [[DKK2]] Predict Incident Low-Impact Fracture in Older Women.
|title=Age-related gene and miRNA expression changes in airways of healthy individuals.
|date=07.2019
|date=06.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31372588
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842487
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403379
}}
}}
==CEBPD==
==RIPK2==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=RIP kinases as modulators of inflammation and immunity.
|date=10.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x
}}
}}
==PPP1R3C==
==RNF10==


* {{medline-title
* {{medline-title
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|title=Reduced RING finger protein 10 expression in macrophages is associated with aging-related inflammation.
|date=03.2019
|date=28.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33249776
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
|full-text-url=https://sci-hub.do/10.1002/2211-5463.13049
}}
}}
==VIPR2==
==RNF13==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=The effects of environmental stressors on candidate aging associated genes.
|date=15.11.2018
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32344118
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1016/j.exger.2020.110952
}}
}}
==ITGA2B==
==RNF144A==


* {{medline-title
* {{medline-title
|title=Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers.
|title=Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease.
|date=04.2018
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29395637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31280115
|full-text-url=https://sci-hub.do/10.1016/j.numecd.2017.12.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732230
}}
}}
==IGF2BP3==
==RNF168==


* {{medline-title
* {{medline-title
|title=Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth.
|title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair.
|date=01.05.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30888162
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b00833
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001
}}
}}
==CRY2==
==RORA==


* {{medline-title
* {{medline-title
|title=Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=21.11.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30463623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247686
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==TRPC7==
==ROS1==


* {{medline-title
* {{medline-title
|title=Nociceptive transient receptor potential canonical 7 ([[TRPC7]]) mediates aging-associated tumorigenesis induced by ultraviolet B.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=01.2020
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31755176
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974716
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==PARK7==
==RPA2==


* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=06.2018
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==HBD==
==RPE65==


* {{medline-title
* {{medline-title
|title=Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection.
|title=Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells.
|date=2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31026271
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30091312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085187
}}
}}
==VPS35==
==RPIA==


* {{medline-title
* {{medline-title
|title=Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development.
|title=Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming.
|date=16.01.2019
|date=20.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654520
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31433975
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359594
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716532
}}
}}
==ABCE1==
==RPL11==


* {{medline-title
* {{medline-title
|title=Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain.
|title=[[NOL12]] Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
|date=27.11.2018
|date=15.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30485811
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354779
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549468
}}
}}
==PRDX6==
==RPL13==


* {{medline-title
* {{medline-title
|title=Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task.
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31417400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684764
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
}}
==RHCG==
==RPL30==


* {{medline-title
* {{medline-title
|title=Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma.
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=06.06.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31170090
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594797
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
}}
==CREM==
==RPL31==


* {{medline-title
* {{medline-title
|title=Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells.
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=11.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31250567
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://sci-hub.do/10.1111/andr.12665
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
==RPL36==
 
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
==ZFPM2==
==RPL37==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=15.11.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
}}
==ABCG1==
==RPL4==


* {{medline-title
* {{medline-title
|title=Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration.
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=08.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29946056
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
==MED25==
==RPS19BP1==


* {{medline-title
* {{medline-title
|title=The [i]HAC1[/i] histone acetyltransferase promotes leaf senescence and regulates the expression of [i]ERF022[/i].
|title=Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence.
|date=08.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31468026
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32659678
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710649
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2020.153275
}}
}}
==CDKN1B==
==RPS6KB1==


* {{medline-title
* {{medline-title
|title=A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis.
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30333755
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176318
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
}}
==SELENBP1==
==RPTOR==


* {{medline-title
* {{medline-title
|title=A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.
|title=Endothelial replicative senescence delayed by the inhibition of [[MTOR]]C1 signaling involves MicroRNA-107.
|date=01.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31557719
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29857052
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812014
|full-text-url=https://sci-hub.do/10.1016/j.biocel.2018.05.016
}}
}}
==LY6D==
==RRAD==


* {{medline-title
* {{medline-title
|title=[[LY6D]]-induced macropinocytosis as a survival mechanism of senescent cells.
|title=Pan-senescence transcriptome analysis identified [[RRAD]] as a marker and negative regulator of cellular senescence.
|date=09.11.2020
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33168631
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391675
|full-text-url=https://sci-hub.do/10.1074/jbc.RA120.013500
|full-text-url=https://sci-hub.do/10.1016/j.freeradbiomed.2018.10.457
}}
}}
==PRKCB==
==RRM1==


* {{medline-title
* {{medline-title
|title=[[MEF2A]] alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells.
|title=α-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1.
|date=18.03.2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885136
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30977294
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423757
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612645
}}
}}
==PLD3==
==RRM2B==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.
|date=16.08.2019
|date=15.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29596868
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994179
}}
}}
==SYNJ1==
==RSF1==


* {{medline-title
* {{medline-title
|title=Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer's Disease.
|title=The SR proteins SF2 and [[RBP1]] regulate triglyceride storage in the fat body of Drosophila.
|date=05.06.2018
|date=27.08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29874583
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277943
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040810
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.06.151
}}
}}
==MYOF==
==RTN4==


* {{medline-title
* {{medline-title
|title=Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|date=08.10.2018
|date=07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30299504
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175028
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
}}
}}
==SLC7A11==
==RUNX3==


* {{medline-title
* {{medline-title
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|title=circLARP4 induces cellular senescence through regulating miR-761/[[RUNX3]]/p53/p21 signaling in hepatocellular carcinoma.
|date=28.10.2017
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30520539
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361555
}}
}}
==CARM1==
==RXFP3==


* {{medline-title
* {{medline-title
|title=[[CARM1]] regulates senescence during airway epithelial cell injury in COPD pathogenesis.
|title=The [[RXFP3]] receptor is functionally associated with cellular responses to oxidative stress and DNA damage.
|date=01.11.2019
|date=03.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31461302
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31794429
|full-text-url=https://sci-hub.do/10.1152/ajplung.00441.2018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932917
}}
}}
==GPD2==
==RXRA==


* {{medline-title
* {{medline-title
|title=Switching off [[IMMP2L]] signaling drives senescence via simultaneous metabolic alteration and blockage of cell death.
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling.
|date=06.2018
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29808012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993829
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923
}}
}}
==RELB==
==RXRG==


* {{medline-title
* {{medline-title
|title=New control of the senescence barrier in breast cancer.
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|date=2020
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32158912
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051141
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
}}
}}
==ARRB2==
==S100A12==


* {{medline-title
* {{medline-title
|title=Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity.
|title=Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model.
|date=12.2019
|date=06.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31304635
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29991479
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801044
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078409
}}
}}
==THRB==
==S100A13==


* {{medline-title
* {{medline-title
|title=Age-associated increase of thyroid hormone receptor β gene promoter methylation coexists with decreased gene expression.
|title=[[S100A13]] promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α.
|date=11.2018
|date=23.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733698
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30670674
|full-text-url=https://sci-hub.do/10.1080/07435800.2018.1469648
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366962
}}
}}
==LY86==
==S100A6==


* {{medline-title
* {{medline-title
|title=Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease.
|title=Sex differences in distribution of cannabinoid receptors (CB1 and CB2), [[S100A6]] and CacyBP/SIP in human ageing hearts.
|date=09.2019
|date=27.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31280115
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30482253
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732230
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258148
}}
}}
==HAMP==
==S1PR3==


* {{medline-title
* {{medline-title
|title=A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity.
|title=Sexual dimorphism of metabolic and vascular dysfunction in aged mice and those lacking the sphingosine 1-phosphate receptor 3.
|date=04.2018
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29408220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28943478
|full-text-url=https://sci-hub.do/10.1016/j.fsi.2018.01.044
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.013
}}
}}
==GSTO1==
==SAA2==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29617422
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884545
}}
}}
==ADH1B==
==SALL1==


* {{medline-title
* {{medline-title
|title=Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde.
|title=[[SALL1]] functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex.
|date=02.2019
|date=06.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29625565
|full-text-url=https://sci-hub.do/10.1016/j.jpsychires.2018.11.007
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889587
}}
}}
==APOBEC1==
==SAMD10==


* {{medline-title
* {{medline-title
|title=Loss of [[APOBEC1]] RNA-editing function in microglia exacerbates age-related CNS pathophysiology.
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|date=12.12.2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29167375
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740644
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
}}
}}
==DMP1==
==SAMD12==


* {{medline-title
* {{medline-title
|title=Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice.
|title=Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom.
|date=07.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29978155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029870
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882010
}}
}}
==AMPH==
==SARM1==


* {{medline-title
* {{medline-title
|title=Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood.
|title=Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.
|date=01.09.2018
|date=03.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29792867
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28978465
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026035
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640801
}}
}}
==ILDR1==
==SAT1==


* {{medline-title
* {{medline-title
|title=Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment.
|title=Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action.
|date=23.10.2019
|date=08.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31645637
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32544364
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469548
}}
}}
==IGF2R==
==SATB2==


* {{medline-title
* {{medline-title
|title=Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks.
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|date=05-06.2018
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29554514
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|full-text-url=https://sci-hub.do/10.1016/j.archger.2018.03.004
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
}}
}}
==MCUR1==
==SCAMP4==


* {{medline-title
* {{medline-title
|title=Cytosolic and mitochondrial Ca  concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation.
|title=[[SCAMP4]] enhances the senescent cell secretome.
|date=09.2019
|date=01.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31377553
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29967290
|full-text-url=https://sci-hub.do/10.1016/j.ceca.2019.102055
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075036
}}
}}
==GLA==
==SCGN==


* {{medline-title
* {{medline-title
|title=TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25.
|title=Detection and evaluation of DNA methylation markers found at [[SCGN]] and [[KLF14]] loci to estimate human age.
|date=17.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29769448
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012510
}}
==JDP2==
 
* {{medline-title
|title=Jun dimerization protein 2 controls hypoxia-induced replicative senescence via both the p16 -pRb and Arf-p53 pathways.
|date=11.2017
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29123987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28854399
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666393
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.011
}}
}}
==CAPRIN1==
==SCN2A==


* {{medline-title
* {{medline-title
|title=Reduced Levels of the Synaptic Functional Regulator FMRP in Dentate Gyrus of the Aging Sprague-Dawley Rat.
|title=Na 1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age.
|date=2017
|date=09.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29218006
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31501495
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703695
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733925
}}
}}
==DPT==
==SCN2B==


* {{medline-title
* {{medline-title
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography.
|title=MicroRNA‑449a regulates the progression of brain aging by targeting [[SCN2B]] in SAMP8 mice.
|date=12.2017
|date=04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32124967
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7053848
}}
}}
==SLC22A23==
==SCN5A==


* {{medline-title
* {{medline-title
|title=Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.
|title=[Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug].
|date=11.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603369
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30175758
|full-text-url=https://sci-hub.do/10.1111/jgh.14149
|full-text-url=https://sci-hub.do/10.1248/yakushi.18-00114
}}
}}
==MEFV==
==SCN9A==


* {{medline-title
* {{medline-title
|title=The grandfather's fever.
|title=The [[SCN9A]] channel and plasma membrane depolarization promote cellular senescence through Rb pathway.
|date=02.2020
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31401792
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29446526
|full-text-url=https://sci-hub.do/10.1007/s10067-019-04741-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946064
}}
}}
==PSMD14==
==SCNN1B==


* {{medline-title
* {{medline-title
|title=Upregulation of deubiquitinase [[PSMD14]] in lung adenocarcinoma (LUAD) and its prognostic significance.
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects.
|date=2020
|date=18.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32226511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086243
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
}}
}}
==ANK2==
==SCO1==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Real-Time PCR Analysis of Metabolism-Related Genes in a Long-Lived Model of C. elegans.
|date=04.07.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32219749
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1007/978-1-0716-0471-7_12
}}
}}
==DSE==
==SCX==


* {{medline-title
* {{medline-title
|title=Impact of Intensive Lifestyle Intervention on Disability-Free Life Expectancy: The Look AHEAD Study.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=05.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29545462
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911793
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==SUMO1==
==SDC2==


* {{medline-title
* {{medline-title
|title=[[SUMO1]]-conjugation is altered during normal aging but not by increased amyloid burden.
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|date=08.2018
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29633471
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052395
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
}}
}}
==HBM==
==SDC3==


* {{medline-title
* {{medline-title
|title=The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis.
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|date=25.09.2019
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31553309
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781972
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
}}
}}
==ALOX5==
==SDC4==


* {{medline-title
* {{medline-title
|title=Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme.
|title=Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1.
|date=01.01.2020
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31642348
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28973369
|full-text-url=https://sci-hub.do/10.1089/ars.2019.7751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627677
}}
}}
==PMP22==
==SDHB==


* {{medline-title
* {{medline-title
|title=Role of microRNAs in senescence and its contribution to peripheral neuropathy in the arsenic exposed population of West Bengal, India.
|title=Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study.
|date=02.2018
|date=12.02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29107899
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32059608
|full-text-url=https://sci-hub.do/10.1016/j.envpol.2017.09.063
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074517
}}
}}
==SRL==
==SELENBP1==


* {{medline-title
* {{medline-title
|title=Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment.
|title=A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity.
|date=04-06.2020
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32432936
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31557719
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812014
}}
}}
==VAMP8==
==SELENOH==


* {{medline-title
* {{medline-title
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells.
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|date=2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
}}
}}
==PSMD11==
==SELENOK==


* {{medline-title
* {{medline-title
|title=The effect and mechanism of 19S proteasome [[PSMD11]]/Rpn6 subunit in D-Galactose induced mimetic aging models.
|title=Dietary selenium deficiency and supplementation differentially modulate the expression of two ER-resident selenoproteins (selenoprotein K and selenoprotein M) in the ovaries of aged mice: Preliminary data.
|date=01.09.2020
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32450067
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32736983
|full-text-url=https://sci-hub.do/10.1016/j.yexcr.2020.112093
|full-text-url=https://sci-hub.do/10.1016/j.repbio.2020.07.006
}}
}}
==GALC==
==SELENOP==


* {{medline-title
* {{medline-title
|title=Analysis of age-related changes in psychosine metabolism in the human brain.
|title=Analyses of Selenotranscriptomes and Selenium Concentrations in Response to Dietary Selenium Deficiency and Age Reveal Common and Distinct Patterns by Tissue and Sex in Telomere-Dysfunctional Mice.
|date=2018
|date=10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29481565
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28855418
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826537
|full-text-url=https://sci-hub.do/10.3945/jn.117.247775
}}
}}
==HNRNPM==
==SELENOT==


* {{medline-title
* {{medline-title
|title=The transcript expression levels of [[HNRNPM]], [[HNRNPA0]] and [[AKAP17A]] splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|date=10.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31292793
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733819
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
}}
}}
==FZD4==
==SELENOV==


* {{medline-title
* {{medline-title
|title=MiR-1292 Targets [[FZD4]] to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway.
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|date=12.2018
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30574422
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284756
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
}}
}}
==GNE==
==SELENOW==


* {{medline-title
* {{medline-title
|title=Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2  mice.
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|date=10.12.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33300446
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|full-text-url=https://sci-hub.do/10.1080/15548627.2020.1850008
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
}}
}}
==DCTN2==
==SEMA3A==


* {{medline-title
* {{medline-title
|title=Dynactin pathway-related gene expression is altered by aging, but not by vitrification.
|title=Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging.
|date=09.2019
|date=05.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31260804
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661929
|full-text-url=https://sci-hub.do/10.1016/j.reprotox.2019.06.011
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2018.12.021
}}
}}
==ETV6==
==SEMA6C==


* {{medline-title
* {{medline-title
|title=[[FOXO1]] and [[ETV6]] genes may represent novel regulators of splicing factor expression in cellular senescence.
|title=Suppression of [[SEMA6C]] promotes preantral follicles atresia with decreased cell junctions in mice ovaries.
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30088951
|full-text-url=https://sci-hub.do/10.1096/fj.201801154R
}}
==DRD4==
 
* {{medline-title
|title=ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children.
|date=04.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30637915
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30256425
|full-text-url=https://sci-hub.do/10.1002/ajmg.b.32711
|full-text-url=https://sci-hub.do/10.1002/jcp.27294
}}
}}
==FANCC==
==SENP1==


* {{medline-title
* {{medline-title
|title=Fanconi Anemia complementation group C protein in metabolic disorders.
|title=Aging-related SUMOylation pattern in the cortex and blood plasma of wild type mice.
|date=21.06.2018
|date=06.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29930218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325714
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046246
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.01.004
}}
}}
==CALR==
==SENP6==


* {{medline-title
* {{medline-title
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender.
|title=Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses.
|date=10.2017
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32827359
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576240
}}
}}
==ITGB2==
==SERPINA1==


* {{medline-title
* {{medline-title
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==NKX6-1==
==SERPINB2==


* {{medline-title
* {{medline-title
|title=The dynamic methylome of islets in health and disease.
|title=An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through [[SERPINB2]].
|date=09.2019
|date=03.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31500828
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31080015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768570
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612665
}}
}}
==SMN2==
==SESN1==


* {{medline-title
* {{medline-title
|title=Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment.
|title=Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis.
|date=01.11.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589162
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751091
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819103
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.006
}}
}}
==FOXL2==
==SESN3==


* {{medline-title
* {{medline-title
|title=Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor.
|title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging.
|date=09.03.2018
|date=25.09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29523193
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5845161
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052
}}
}}
==PPP2R1A==
==SF1==


* {{medline-title
* {{medline-title
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|title=Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice.
|date=15.04.2019
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30576894
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
|full-text-url=https://sci-hub.do/10.1016/j.ecoenv.2018.12.034
}}
}}
==SOX11==
==SFPQ==


* {{medline-title
* {{medline-title
|title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
|title=Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis.
|date=10.08.2017
|date=08.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32267831
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185106
}}
}}
==EDEM1==
==SFRP1==


* {{medline-title
* {{medline-title
|title=Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to [[GDF15]] expression.
|title=[Role and alterations of DNA methylation during the aging and cancer].
|date=08.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912009
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|full-text-url=https://sci-hub.do/10.1007/s13105-019-00676-6
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
}}
}}
==GCNT2==
==SFRP2==


* {{medline-title
* {{medline-title
|title=Human iPSC-derived [[MSC]]s (i[[MSC]]s) from aged individuals acquire a rejuvenation signature.
|title=[Role and alterations of DNA methylation during the aging and cancer].
|date=18.03.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30885246
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29291647
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423778
|full-text-url=https://sci-hub.do/10.1556/650.2018.30927
}}
}}
==CRYAB==
==SFRP5==


* {{medline-title
* {{medline-title
|title=Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells.
|title=[[SFRP5]] serves a beneficial role in arterial aging by inhibiting the proliferation, migration and inflammation of smooth muscle cells.
|date=28.12.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30389787
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30221661
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311499
|full-text-url=https://sci-hub.do/10.3892/mmr.2018.9467
}}
}}
==ESR1==
==SGK1==


* {{medline-title
* {{medline-title
|title=Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement.
|title=Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells.
|date=05.01.2018
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29416771
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223380
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788639
|full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.120.14642
}}
}}
==ADD2==
==SGSH==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=MPS-IIIA mice acquire autistic behaviours with age.
|date=04.07.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29520737
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1007/s10545-018-0160-9
}}
}}
==DLL4==
==SH2B3==


* {{medline-title
* {{medline-title
|title=Dynamic regulation of [[NOTCH1]] activation and Notch ligand expression in human thymus development.
|title=Genome-wide meta-analysis associates HLA-DQA1/DRB1 and [[LPA]] and lifestyle factors with human longevity.
|date=13.08.2018
|date=13.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30042180
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29030599
|full-text-url=https://sci-hub.do/10.1242/dev.165597
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715013
}}
}}
==TLR6==
==SHANK3==


* {{medline-title
* {{medline-title
|title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.
|title=Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background.
|date=05.2018
|date=10.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30305163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180595
}}
}}
==TNP1==
==SHD==


* {{medline-title
* {{medline-title
|title=Cytological and molecular aspects of the ageing sperm.
|title=Does self-reported hearing difficulty decrease older adults' cognitive and physical functioning? The mediating role of social isolation.
|date=01.02.2019
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33036703
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
|full-text-url=https://sci-hub.do/10.1016/j.maturitas.2020.06.011
}}
}}
==ACTA2==
==SIK3==


* {{medline-title
* {{medline-title
|title=Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice.
|title=Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids.
|date=2018
|date=25.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30270325
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31566214
|full-text-url=https://sci-hub.do/10.1248/bpb.b18-00217
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518561
}}
}}
==LGI1==
==SIL1==


* {{medline-title
* {{medline-title
|title=Antibody-associated CNS syndromes without signs of inflammation in the elderly.
|title=[[SIL1]], the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology.
|date=03.10.2017
|date=10.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28878050
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29666155
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631166
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992605
}}
}}
==AKT3==
==SIX3==


* {{medline-title
* {{medline-title
|title=Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma.
|title=CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type.
|date=10.2018
|date=30.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102368
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135677
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265269
}}
}}
==NKAP==
==SKAP2==


* {{medline-title
* {{medline-title
|title=[[NKAP]] Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors.
|title=Longevity-related molecular pathways are subject to midlife "switch" in humans.
|date=2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31632967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31168962
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783958
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612641
}}
}}
==FOXP4==
==SKI==


* {{medline-title
* {{medline-title
|title=Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization.
|title=Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells.
|date=06.11.2018
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30400853
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29700792
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219247
|full-text-url=https://sci-hub.do/10.1007/s11684-017-0586-8
}}
}}
==RPL13==
==SLC15A1==


* {{medline-title
* {{medline-title
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|title=Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing.
|date=2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019300
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3413-x
}}
}}
==NACA==
==SLC15A2==


* {{medline-title
* {{medline-title
|title=Age and Sex Are Strongly Correlated to the Rate and Type of Mountain Injuries Requiring Search and Rescue Missions.
|title=Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing.
|date=12.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31699646
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019300
|full-text-url=https://sci-hub.do/10.1016/j.wem.2019.06.016
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3413-x
}}
}}
==FAM13A==
==SLC16A7==


* {{medline-title
* {{medline-title
|title=Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease.
|title=Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach.
|date=05.2018
|date=23.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29517586
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33095951
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895171
|full-text-url=https://sci-hub.do/10.1111/jdv.17014
}}
}}
==FBN2==
==SLC19A1==


* {{medline-title
* {{medline-title
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging.
|title=Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer.
|date=26.10.2018
|date=30.03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29682186
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908287
}}
}}
==ADRA2A==
==SLC1A5==


* {{medline-title
* {{medline-title
|title=α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway.
|title=[[SLC1A5]] glutamine transporter is a target of [[MYC]] and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice.
|date=2020
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33116632
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30909319
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574911
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516164
}}
}}
==HPSE==
==SLC22A14==
 
* {{medline-title
|title=Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin.
|date=07.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32159248
|full-text-url=https://sci-hub.do/10.1002/cbin.11339
}}
==QRFPR==


* {{medline-title
* {{medline-title
Строка 12 103: Строка 11 983:
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
}}
==MCM8==
==SLC22A23==


* {{medline-title
* {{medline-title
|title=Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study.
|title=Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.
|date=2017
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29073238
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29603369
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658184
|full-text-url=https://sci-hub.do/10.1111/jgh.14149
}}
}}
==LGR6==
==SLC24A5==


* {{medline-title
* {{medline-title
|title=Effect of defensins-containing eye cream on periocular rhytids and skin quality.
|title=[A question of colour].
|date=08.2020
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32614135
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29384103
|full-text-url=https://sci-hub.do/10.1111/jocd.13424
|full-text-url=https://sci-hub.do/10.1051/medsci/20183401020
}}
}}
==NLRP12==
==SLC26A2==


* {{medline-title
* {{medline-title
|title=Persistent DNA damage-induced [[NLRP12]] improves hematopoietic stem cell function.
|title=Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis.
|date=21.05.2020
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434992
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31914611
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259522
|full-text-url=https://sci-hub.do/10.1096/fj.201901040RR
}}
}}
==DAPK2==
==SLC2A4==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=04.07.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
==HLA-DQA1==
==SLC30A1==


* {{medline-title
* {{medline-title
|title=17th IHIW component "Immunogenetics of Ageing" - New NGS data.
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|date=09.2019
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31331679
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773488
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
}}
}}
==COL13A1==
==SLC30A10==


* {{medline-title
* {{medline-title
|title=[Alu insertion-deletion polymorphism of [[COL13A1]] and [[LAMA2]] genes: The analysis of association with longevity].
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|date=10.2016
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29369589
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
 
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
}}
}}
==CABLES1==
==SLC30A5==


* {{medline-title
* {{medline-title
|title=[[CABLES1]] Deficiency Impairs Quiescence and Stress Responses of Hematopoietic Stem Cells in Intrinsic and Extrinsic Manners.
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|date=13.08.2019
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327733
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700604
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
}}
}}
==CCND2==
==SLC39A6==


* {{medline-title
* {{medline-title
|title=Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma.
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|date=10.2018
|date=01.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097674
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135677
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
}}
}}
==CD226==
==SLC41A1==


* {{medline-title
* {{medline-title
|title=T-cell Immunoglobulin and ITIM Domain Contributes to CD8  T-cell Immunosenescence.
|title=Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis.
|date=04.2018
|date=08.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29349889
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31076559
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535063
}}
}}
==ACAD10==
==SLC52A2==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.
|date=12.2017
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053833
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808726
}}
}}
==DSPP==
==SLC52A3==


* {{medline-title
* {{medline-title
|title=Effects of [i]p[/i]-Cresol on Senescence, Survival, Inflammation, and Odontoblast Differentiation in Canine Dental Pulp Stem Cells.
|title=Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.
|date=21.09.2020
|date=01.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32967298
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053833
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808726
}}
}}
==POLR3A==
==SLC7A11==


* {{medline-title
* {{medline-title
|title=Nucleolar disruption, activation of P53 and premature senescence in [[POLR3A]]-mutated Wiedemann-Rautenstrauch syndrome fibroblasts.
|title=[[SOCS1]] regulates senescence and ferroptosis by modulating the expression of p53 target genes.
|date=12.2020
|date=28.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32976914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29081404
|full-text-url=https://sci-hub.do/10.1016/j.mad.2020.111360
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680560
}}
}}
==RCAN1==
==SMAD1==


* {{medline-title
* {{medline-title
|title=Mitochondrial dysfunction and endoplasmic reticulum stress involved in oocyte aging: an analysis using single-cell RNA-sequencing of mouse oocytes.
|title=TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands.
|date=08.06.2019
|date=26.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31176373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31779094
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556043
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928867
}}
}}
==PCCA==
==SMARCA5==


* {{medline-title
* {{medline-title
|title=Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism.
|title=The epigenetic regulator [[SIRT7]] guards against mammalian cellular senescence induced by ribosomal DNA instability.
|date=03.2018
|date=13.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29159707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29728458
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052228
}}
}}
==GABARAP==
==SMARCB1==


* {{medline-title
* {{medline-title
|title=Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy.
|title=High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.
|date=18.08.2020
|date=17.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32811819
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29045843
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434891
|full-text-url=https://sci-hub.do/10.1016/j.celrep.2017.09.085
}}
}}
==TIMP2==
==SMARCD1==


* {{medline-title
* {{medline-title
|title=The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma.
|title=Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells.
|date=2019
|date=12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30252623
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30155609
|full-text-url=https://sci-hub.do/10.1080/09537104.2018.1514110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269360
}}
}}
==DSCAM==
==SMC2==


* {{medline-title
* {{medline-title
|title=Age- and speed-dependent modulation of gaits in [[DSCAM]]  mutant mice.
|title=The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence.
|date=01.02.2018
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29093169
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336977
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867377
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.065
}}
}}
==SESN3==
==SMC3==


* {{medline-title
* {{medline-title
|title=Autophagy mediators ([[FOXO1]], [[SESN3]] and [[TSC2]]) in Lewy body disease and aging.
|title=Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice.
|date=25.09.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29966750
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667147
|full-text-url=https://sci-hub.do/10.1016/j.neulet.2018.06.052
|full-text-url=https://sci-hub.do/10.1007/s11655-018-2835-3
}}
}}
==GPR6==
==SMC4==


* {{medline-title
* {{medline-title
|title=Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy.
|title=The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence.
|date=22.09.2020
|date=10.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32959881
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336977
|full-text-url=https://sci-hub.do/10.1093/infdis/jiaa599
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.065
}}
}}
==NR3C1==
==SMN1==


* {{medline-title
* {{medline-title
|title=Glucocorticoid receptor ([[NR3C1]]) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians.
|title=Changing respiratory expectations with the new disease trajectory of nusinersen treated spinal muscular atrophy [SMA] type 1.
|date=02.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30553025
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30414815
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.12.006
|full-text-url=https://sci-hub.do/10.1016/j.prrv.2018.07.002
}}
}}
==CHSY1==
==SMN2==


* {{medline-title
* {{medline-title
|title=Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in [i]skt[/i] Mice.
|title=Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment.
|date=01.2020
|date=01.11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31754016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31589162
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944401
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819103
}}
}}
==RAD50==
==SMO==


* {{medline-title
* {{medline-title
|title=Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells.
|title=Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus.
|date=01.09.2018
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29775409
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30391523
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172637
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342483
}}
}}
==INPP5A==
==SMOX==


* {{medline-title
* {{medline-title
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|title=Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine.
|date=25.07.2018
|date=14.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29443878
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872171
}}
}}
==GREM1==
==SMPD1==


* {{medline-title
* {{medline-title
|title=[[GREM1]] inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells.
|title=Alterations in Lipid Profile of the Aging Kidney Identified by MALDI Imaging Mass Spectrometry.
|date=09.03.2020
|date=05.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32151168
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31244212
|full-text-url=https://sci-hub.do/10.1080/03008207.2020.1736054
|full-text-url=https://sci-hub.do/10.1021/acs.jproteome.9b00108
}}
}}
==TLR8==
==SMYD2==


* {{medline-title
* {{medline-title
|title=[[TLR8]]-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy.
|title=Collaboration of [[MYC]] and [[RUNX2]] in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity.
|date=08.01.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30344014
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31257681
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050437
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772115
}}
}}
==HSPA13==
==SNAI2==


* {{medline-title
* {{medline-title
|title=Genetic associations with age of menopause in familial longevity.
|title=Reawakening of dormant estrogen-dependent human breast cancer cells by bone marrow stroma secretory senescence.
|date=10.2019
|date=17.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30119678
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098600
}}
}}
==APOA1==
==SND1==


* {{medline-title
* {{medline-title
|title=Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I.
|title=[Downregulation of [[SND1]] Expression Accelerates Cell Senescence of Human Diploid Fibroblasts 2BS via Modulating the SASP].
|date=08.2018
|date=05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29623474
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32543144
|full-text-url=https://sci-hub.do/10.1007/s10534-018-0101-y
|full-text-url=https://sci-hub.do/10.12182/20200560504
}}
}}
==MICA==
==SOS1==


* {{medline-title
* {{medline-title
|title=Derivation and Validation of a Geriatric-Sensitive Perioperative Cardiac Risk Index.
|title=Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via [[IRS1]]/[[GRB2]]/ [[SOS1]], GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice.
|date=16.11.2017
|date=21.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29146612
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30669571
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721761
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356397
}}
}}
==HOXC4==
==SOX11==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.
|date=11.2017
|date=10.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28797244
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553741
}}
}}
==VAMP2==
==SOX13==


* {{medline-title
* {{medline-title
|title=Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission.
|title=In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases.
|date=01.08.2018
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29950309
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31520345
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068464
|full-text-url=https://sci-hub.do/10.1007/s10522-019-09834-1
}}
}}
==RTN4==
==SOX4==


* {{medline-title
* {{medline-title
|title=Cell fate regulation by reticulon-4 in human prostate cancers.
|title=Age-induced accumulation of methylmalonic acid promotes tumour progression.
|date=07.2019
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30480803
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32814897
|full-text-url=https://sci-hub.do/10.1002/jcp.27704
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2630-0
}}
}}
==SGK1==
==SP1==


* {{medline-title
* {{medline-title
|title=Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells.
|title=Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data.
|date=05.2020
|date=15.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32223380
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641220
|full-text-url=https://sci-hub.do/10.1161/HYPERTENSIONAHA.120.14642
|full-text-url=https://sci-hub.do/10.1016/j.gene.2018.12.063
}}
}}
==HDAC8==
==SP2==


* {{medline-title
* {{medline-title
|title=Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography.
|date=09.2018
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29951776
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096771
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0
}}
}}
==UMOD==
==SP7==


* {{medline-title
* {{medline-title
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes.
|title=microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
|date=03.2019
|date=06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30506733
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468
|full-text-url=https://sci-hub.do/10.1002/jcb.28223
}}
}}
==DRAM1==
==SPATS2L==


* {{medline-title
* {{medline-title
|title=Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.
|title=Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.
|date=12.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29988085
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585438
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818258
}}
}}
==SELENOH==
==SPG7==


* {{medline-title
* {{medline-title
|title=The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration.
|title=Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration.
|date=03.2019
|date=21.02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30229511
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467464
|full-text-url=https://sci-hub.do/10.1007/s12011-018-1521-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833341
}}
}}
==CASK==
==SPHK1==


* {{medline-title
* {{medline-title
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats.
|title=Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina.
|date=01.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30997640
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425817
}}
}}
==ARHGAP18==
==SPHK2==


* {{medline-title
* {{medline-title
|title=Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma
|title=Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.
|date=18.11.2019
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31327185
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30886000
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446199
}}
}}
==GSTK1==
==SPON1==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=[[APOE]] influences working memory in non-demented elderly through an interaction with [[SPON1]] rs2618516.
|date=12.2018
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573041
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866309
}}
}}
==HOXD8==
==SPP1==


* {{medline-title
* {{medline-title
|title=Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts.
|title=Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age.
|date=2020
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32849838
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397924
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431633
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908781
}}
}}
==ABL1==
==SPRTN==


* {{medline-title
* {{medline-title
|title=European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia.
|title=Tandem Deubiquitination and Acetylation of [[SPRTN]] Promotes DNA-Protein Crosslink Repair and Protects against Aging.
|date=04.2020
|date=03.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32127639
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32649882
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214240
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484104
}}
}}
==TSHR==
==SRD5A2==


* {{medline-title
* {{medline-title
|title=TSH-independent release of thyroid hormones through cold exposure in aging rats.
|title=Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II.
|date=27.10.2017
|date=11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163760
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32125089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685681
|full-text-url=https://sci-hub.do/10.1111/jocd.13355
}}
}}
==AACS==
==SRI==


* {{medline-title
* {{medline-title
|title=Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study.
|title=The Role of Aging, Drug Dependence, and Hepatitis C Comorbidity in Alcoholism Cortical Compromise.
|date=07.11.2020
|date=01.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33170149
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29541774
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695390
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875381
}}
}}
==POU3F2==
==SRL==


* {{medline-title
* {{medline-title
|title=[[POU3F2]] participates in cognitive function and adult hippocampal neurogenesis via mammalian-characteristic amino acid repeats.
|title=Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment.
|date=02.2018
|date=04-06.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28782255
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32432936
|full-text-url=https://sci-hub.do/10.1111/gbb.12408
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250001
}}
}}
==SMC4==
==SRM==


* {{medline-title
* {{medline-title
|title=The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence.
|title=[Geriatric specificities of localized renal cell carcinoma].
|date=10.11.2018
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30336977
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31771769
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.10.065
|full-text-url=https://sci-hub.do/10.1016/j.purol.2019.08.281
}}
}}
==VCP==
==SRPK1==


* {{medline-title
* {{medline-title
|title=The role of air pollution and lung function in cognitive impairment.
|title=[Age-related changes in the content of serine-arginine protein kinase 1 ([[SRPK1]]) in human dermis.]
|date=02.2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467204
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29322729
|full-text-url=https://sci-hub.do/10.1183/13993003.01963-2017
 
}}
}}
==ADCK1==
==SRSF1==


* {{medline-title
* {{medline-title
|title=Functional analysis of Aarf domain-containing kinase 1 in Drosophila melanogaster.
|title=Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
|date=09.2019
|date=09.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31175694
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037605
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271681
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2018.06.029
}}
}}
==MPL==
==SRSF3==


* {{medline-title
* {{medline-title
|title=Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender.
|title=Alternative polyadenylation dependent function of splicing factor [[SRSF3]] contributes to cellular senescence.
|date=10.2017
|date=04.03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28948454
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30835716
|full-text-url=https://sci-hub.do/10.1007/s11899-017-0411-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428108
}}
}}
==NOBOX==
==SRY==


* {{medline-title
* {{medline-title
|title=Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model.
|title=Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics.
|date=18.10.2017
|date=26.12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29047400
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29371932
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648463
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768349
}}
}}
==MUL1==
==SSBP2==


* {{medline-title
* {{medline-title
|title=Effects of [[MUL1]] and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models.
|title=Genetic associations with age of menopause in familial longevity.
|date=28.05.2019
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31138137
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540415
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==HRG==
==ST18==


* {{medline-title
* {{medline-title
|title=Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice.
|title=[Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao].
|date=10.2017
|date=04.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29021712
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28879748
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628339
|full-text-url=https://sci-hub.do/10.4268/cjcmm20160724
}}
}}
==ADK==
==ST6GAL1==


* {{medline-title
* {{medline-title
|title=Deletion of pancreatic β-cell adenosine kinase improves glucose homeostasis in young mice and ameliorates streptozotocin-induced hyperglycaemia.
|title=Glycobiology of Aging.
|date=07.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31044530
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30779020
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584724
|full-text-url=https://sci-hub.do/10.1007/978-981-13-2835-0_17
}}
}}
==SPON1==
==STC1==


* {{medline-title
* {{medline-title
|title=[[APOE]] influences working memory in non-demented elderly through an interaction with [[SPON1]] rs2618516.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=07.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29573041
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866309
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==EPG5==
==STC2==


* {{medline-title
* {{medline-title
|title=Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom.
|title=Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and [[STC2]].
|date=05.2018
|date=05.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29486404
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31761296
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882010
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904802
}}
}}
==SLC39A6==
==STK3==


* {{medline-title
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|title=Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence.
|date=01.12.2017
|date=11.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30478051
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294934
}}
}}
==SLC22A14==
==STK32C==
 
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
}}
==DLL1==
 
* {{medline-title
|title=MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting [[DLL1]] and Regulating PI3K/AKT Pathway.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30048987
|full-text-url=https://sci-hub.do/10.1159/000492090
}}
==HOXA3==


* {{medline-title
* {{medline-title
Строка 12 567: Строка 12 431:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==OCLN==
==STN1==


* {{medline-title
* {{medline-title
|title=Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats.
|title=[[CTC1]]-[[STN1]] coordinates G- and C-strand synthesis to regulate telomere length.
|date=17.07.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31242723
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29774655
|full-text-url=https://sci-hub.do/10.1021/acs.jafc.9b02567
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479
}}
}}
==DTL==
==STOML2==


* {{medline-title
* {{medline-title
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|title=Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease.
|date=2018
|date=2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29201274
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672147
}}
}}
==SENP6==
==STX17==


* {{medline-title
* {{medline-title
|title=Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses.
|title=Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and [[XIAP]].
|date=10.2020
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32827359
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576240
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.05.017
}}
}}
==GHSR==
==SUCNR1==


* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=[The effect of Mexidol on cerebral mitochondriogenesis at a young age and during aging].
|date=06.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32105271
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://sci-hub.do/10.17116/jnevro202012001162
}}
}}
==SRD5A2==
==SUGCT==


* {{medline-title
* {{medline-title
|title=Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II.
|title=Knockout of the non-essential gene [[SUGCT]] creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
|date=11.2020
|date=09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32125089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31722069
|full-text-url=https://sci-hub.do/10.1111/jocd.13355
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426296
}}
}}
==KIF1A==
==SUMO1==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=[[SUMO1]]-conjugation is altered during normal aging but not by increased amyloid burden.
|date=04.07.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29633471
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052395
}}
}}
==GSTT2==
==SUN1==


* {{medline-title
* {{medline-title
|title=Age-associated changes in GSH S-transferase gene/proteins in livers of rats.
|title=Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging.
|date=12.2018
|date=26.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30444463
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748684
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397528
}}
}}
==HOXA4==
==SUN2==


* {{medline-title
* {{medline-title
|title=Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes.
|title=Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging.
|date=10.2019
|date=26.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31259468
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30808750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718529
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397528
}}
}}
==SOX4==
==SURF1==


* {{medline-title
* {{medline-title
|title=Age-induced accumulation of methylmalonic acid promotes tumour progression.
|title=Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.
|date=09.2020
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32814897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696791
|full-text-url=https://sci-hub.do/10.1038/s41586-020-2630-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052393
}}
}}
==DAZL==
==SUZ12==


* {{medline-title
* {{medline-title
|title=[[DAZL]] Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.
|title=Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells.
|date=30.10.2018
|date=05.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380414
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30194939
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878787
|full-text-url=https://sci-hub.do/10.1016/j.ejphar.2018.09.005
}}
}}
==RBM25==
==SV2B==


* {{medline-title
* {{medline-title
|title=HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif.
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|date=29.04.2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31039132
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
}}
}}
==VEGFA==
==SV2C==


* {{medline-title
* {{medline-title
|title=APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease.
|title=Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C.
|date=03.2020
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31791659
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29713895
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129247
}}
}}
==SRSF1==
==SYNE1==


* {{medline-title
* {{medline-title
|title=Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
|title=Nesprin-1 impact on tumorigenic cell phenotypes.
|date=09.2018
|date=02.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30037605
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31741263
|full-text-url=https://sci-hub.do/10.1016/j.mehy.2018.06.029
|full-text-url=https://sci-hub.do/10.1007/s11033-019-05184-w
}}
}}
==MYO1F==
==SYNJ1==


* {{medline-title
* {{medline-title
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|title=Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer's Disease.
|date=2019
|date=05.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29874583
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040810
}}
}}
==CXCL13==
==SYNJ2==


* {{medline-title
* {{medline-title
|title=RNA-seq data from C-X-C chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype.
|title=DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
|date=08.2020
|date=25.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32642521
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30045751
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334305
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058387
}}
}}
==SURF1==
==SYP==


* {{medline-title
* {{medline-title
|title=Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.
|title=The neuropeptide-12 improves recognition memory and neuronal plasticity of the limbic system in old rats.
|date=08.2018
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29696791
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29740871
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052393
|full-text-url=https://sci-hub.do/10.1002/syn.22036
}}
}}
==MUC7==
==SYT1==


* {{medline-title
* {{medline-title
|title=Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model.
|title=Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins.
|date=24.09.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31554163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29670520
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835954
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893842
}}
}}
==DHRS2==
==SYT7==


* {{medline-title
* {{medline-title
|title=Acute [[HSF1]] depletion induces cellular senescence through the [[MDM2]]-p53-p21 pathway in human diploid fibroblasts.
|title=Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells.
|date=08.05.2018
|date=28.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29632240
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30647108
|full-text-url=https://sci-hub.do/10.1242/jcs.210724
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367206
}}
}}
==RPL4==
==TAAR1==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Minimal Age-Related Alterations in Behavioral and Hematological Parameters in Trace Amine-Associated Receptor 1 ([[TAAR1]]) Knockout Mice.
|date=2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31399838
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://sci-hub.do/10.1007/s10571-019-00721-4
}}
}}
==BMP6==
==TAF7==


* {{medline-title
* {{medline-title
|title=Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology.
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|date=06.11.2018
|date=22.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30352848
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233090
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
}}
}}
==ABI3BP==
==TAF7L==


* {{medline-title
* {{medline-title
|title=Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing [[ABI3BP]] in gallbladder cancer cells.
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|date=07.06.2019
|date=22.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174563
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555920
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
}}
}}
==AIF1==
==TARDBP==


* {{medline-title
* {{medline-title
|title=Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.
|title=Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.
|date=06.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29280055
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577934
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930062
|full-text-url=https://sci-hub.do/10.1016/j.ajpath.2018.03.002
}}
}}
==USP30==
==TAS1R2==


* {{medline-title
* {{medline-title
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i].
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects.
|date=29.05.2018
|date=18.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
}}
}}
==SPHK2==
==TBC1D1==


* {{medline-title
* {{medline-title
|title=Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|date=04.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30886000
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446199
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
}}
}}
==ITGAM==
==TCERG1==


* {{medline-title
* {{medline-title
|title=Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging.
|title=The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity.
|date=2019
|date=17.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31732940
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31316054
|full-text-url=https://sci-hub.do/10.1007/978-3-030-28524-1_11
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637209
}}
}}
==PRR9==
==TCF15==


* {{medline-title
* {{medline-title
|title=Circadian control of [i]ORE1[/i] by [[PRR9]] positively regulates leaf senescence in [i]Arabidopsis[/i].
|title=Loss of Neurogenesis in Aging Hydra.
|date=14.08.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30065116
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30912256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099856
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586502
}}
}}
==PIK3R2==
==TCF21==


* {{medline-title
* {{medline-title
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|title=Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3.
|date=06.2019
|date=22.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29748384
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016453
}}
}}
==MAVS==
==TCF7==


* {{medline-title
* {{medline-title
|title=Spontaneous activation of a [[MAVS]]-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes.
|title=Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice.
|date=10.2017
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28822807
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29206307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600710
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925424
}}
}}
==FNTA==
==TCTA==


* {{medline-title
* {{medline-title
|title=The Hip Morphology Changes with Ageing in Asian Population.
|title=Exciplex-Forming Cohost for High Efficiency and High Stability Phosphorescent Organic Light-Emitting Diodes.
|date=2018
|date=17.01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30363710
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29265796
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180959
|full-text-url=https://sci-hub.do/10.1021/acsami.7b15034
}}
}}
==PRDM1==
==TDG==


* {{medline-title
* {{medline-title
|title=Age-related changes in the [[BACH2]] and [[PRDM1]] genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients.
|title=lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/[[TDG]] axis.
|date=17.01.2019
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654767
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31282110
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337793
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714223
}}
}}
==ADAR==
==TDP1==


* {{medline-title
* {{medline-title
|title=Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis.
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|date=09.2018
|date=12.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29986212
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037660
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
}}
}}
==CD55==
==TECPR2==


* {{medline-title
* {{medline-title
|title=Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia.
|title=Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging.
|date=15.11.2018
|date=01-03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30429373
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30681437
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303009
|full-text-url=https://sci-hub.do/10.1097/WAD.0000000000000294
}}
}}
==HMGA1==
==TEF==


* {{medline-title
* {{medline-title
|title=Characterization of [i][[HMGA1]]P6[/i] transgenic mouse embryonic fibroblasts.
|title=Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response.
|date=09.2020
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32787507
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32189112
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7513866
|full-text-url=https://sci-hub.do/10.1007/s10522-020-09869-9
}}
}}
==IL6ST==
==TEP1==


* {{medline-title
* {{medline-title
|title=The senescent status of endothelial cells affects proliferation, inflammatory profile and [[SOX2]] expression in bone marrow-derived mesenchymal stem cells.
|title=[Influence of Age on the Susceptibility of  Anopheles stephensi to Plasmodium berghei Infection].
|date=06.2019
|date=12.2016
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30822486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30141604
|full-text-url=https://sci-hub.do/10.1016/j.exger.2019.02.014
 
}}
}}
==MMP14==
==TES==


* {{medline-title
* {{medline-title
|title=Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells.
|title=The Effects of Electrical Stimulation Pulse Duration on Lingual Palatal Pressure Measures During Swallowing in Healthy Older Adults.
|date=12.2017
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29344220
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820657
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755030
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456514
}}
}}
==ANPEP==
==TET3==


* {{medline-title
* {{medline-title
|title=Aminopeptidase N expression in the endometrium could affect endometrial receptivity.
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|date=25.06.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31056265
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2019.04.174
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
}}
}}
==CAV1==
==TFPI==


* {{medline-title
* {{medline-title
|title=Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine.
|title=Identification of cardiovascular health gene variants related to longevity in a Chinese population.
|date=24.04.2019
|date=07.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30690072
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32897244
|full-text-url=https://sci-hub.do/10.1016/j.jep.2019.01.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521493
}}
}}
==RIPK2==
==TGDS==


* {{medline-title
* {{medline-title
|title=RIP kinases as modulators of inflammation and immunity.
|title=The evaluation and design of a short depression screening tool in Turkish older adults.
|date=09.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131615
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29560848
|full-text-url=https://sci-hub.do/10.1038/s41590-018-0188-x
|full-text-url=https://sci-hub.do/10.1017/S1041610218000236
}}
}}
==MAPK8==
==TGFB1==


* {{medline-title
* {{medline-title
|title=Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats.
|title=Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease.
|date=02.2019
|date=11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30661688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28812215
|full-text-url=https://sci-hub.do/10.1016/j.clnesp.2018.10.003
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665708
}}
}}
==GJC2==
==TGFBR1==


* {{medline-title
* {{medline-title
|title=Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging.
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|date=10.2020
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32629311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|full-text-url=https://sci-hub.do/10.1016/j.neurobiolaging.2020.04.017
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
}}
}}
==OSGEP==
==TGFBR2==


* {{medline-title
* {{medline-title
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|title=TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
|date=11.04.2019
|date=08.05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31068441
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102613
}}
}}
==KIFC3==
==TGM2==


* {{medline-title
* {{medline-title
|title=Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging.
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|date=08.2018
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29845728
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052466
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
}}
}}
==BMPR2==
==THBS1==


* {{medline-title
* {{medline-title
|title=Centenarians Overexpress Pluripotency-Related Genes.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=16.08.2019
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30052797
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://sci-hub.do/10.1093/gerona/gly168
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==RGS2==
==THBS4==


* {{medline-title
* {{medline-title
|title=Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone.
|title=Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment.
|date=01.05.2019
|date=18.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31043680
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31160442
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494869
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589664
}}
}}
==KRT18==
==THEMIS==


* {{medline-title
* {{medline-title
|title=Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
|title=Lifetime benefits of early detection and treatment of diabetic kidney disease.
|date=11.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30071357
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31150444
|full-text-url=https://sci-hub.do/10.1016/j.arr.2018.07.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544227
}}
}}
==IL15==
==THRB==


* {{medline-title
* {{medline-title
|title=Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of [[IL15]].
|title=Age-associated increase of thyroid hormone receptor β gene promoter methylation coexists with decreased gene expression.
|date=27.04.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32221610
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29733698
|full-text-url=https://sci-hub.do/10.1093/ageing/afaa035
|full-text-url=https://sci-hub.do/10.1080/07435800.2018.1469648
}}
}}
==PRKG1==
==TIMP2==


* {{medline-title
* {{medline-title
|title=Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis.
|title=The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma.
|date=15.07.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29660387
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30252623
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.04.007
|full-text-url=https://sci-hub.do/10.1080/09537104.2018.1514110
}}
}}
==GDF5==
==TINF2==


* {{medline-title
* {{medline-title
|title=An embryonic CaVβ1 isoform promotes muscle mass maintenance via [[GDF5]] signaling in adult mouse.
|title=Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening.
|date=06.11.2019
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31694926
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29055871
|full-text-url=https://sci-hub.do/10.1126/scitranslmed.aaw1131
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650655
}}
}}
==SLC15A1==
==TJP1==


* {{medline-title
* {{medline-title
|title=Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing.
|title=Morphological and immunohistochemical characteristics of the equine corneal epithelium.
|date=02.2019
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30019300
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30767359
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3413-x
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900071
}}
}}
==WAS==
==TLR3==


* {{medline-title
* {{medline-title
|title=Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number.
|title=Repetitive [[TLR3]] activation in the lung induces skeletal muscle adaptations and cachexia.
|date=09.11.2017
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129830
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29452288
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723686
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911410
}}
}}
==VPS13C==
==TLR5==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition.
|date=04.07.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30089902
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://sci-hub.do/10.1038/s41586-018-0395-5
}}
}}
==EPHA1==
==TLR6==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=Decreased [[NLRP3]] inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.
|date=16.08.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29203400
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869149
}}
}}
==CDO1==
==TLR8==


* {{medline-title
* {{medline-title
|title=The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway.
|title=[[TLR8]]-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy.
|date=19.09.2018
|date=08.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30131986
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30344014
|full-text-url=https://sci-hub.do/10.1039/c8fo00740c
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050437
}}
}}
==WDR5==
==TMEM119==


* {{medline-title
* {{medline-title
|title=Inhibition of the H3K4 methyltransferase MLL1/[[WDR5]] complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16 .
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|date=11.2019
|date=02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570196
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|full-text-url=https://sci-hub.do/10.1016/j.kint.2019.06.021
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
}}
}}
==SHD==
==TNFSF15==


* {{medline-title
* {{medline-title
|title=Does self-reported hearing difficulty decrease older adults' cognitive and physical functioning? The mediating role of social isolation.
|title=Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens.
|date=11.2020
|date=11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33036703
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30269026
|full-text-url=https://sci-hub.do/10.1016/j.maturitas.2020.06.011
|full-text-url=https://sci-hub.do/10.1016/j.cyto.2018.09.015
}}
}}
==SEMA6C==
==TNNI1==


* {{medline-title
* {{medline-title
|title=Suppression of [[SEMA6C]] promotes preantral follicles atresia with decreased cell junctions in mice ovaries.
|title=Regular aerobic exercise-ameliorated troponin I carbonylation to mitigate aged rat soleus muscle functional recession.
|date=04.2019
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30256425
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30820991
|full-text-url=https://sci-hub.do/10.1002/jcp.27294
|full-text-url=https://sci-hub.do/10.1113/EP087564
}}
}}
==TCF21==
==TNP1==


* {{medline-title
* {{medline-title
|title=Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3.
|title=Cytological and molecular aspects of the ageing sperm.
|date=22.06.2018
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29748384
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016453
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
}}
}}
==USP14==
==TNP2==


* {{medline-title
* {{medline-title
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|title=Cytological and molecular aspects of the ageing sperm.
|date=07.2018
|date=01.02.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30551142
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
|full-text-url=https://sci-hub.do/10.1093/humrep/dey357
}}
}}
==MS4A4E==
==TNPO3==


* {{medline-title
* {{medline-title
|title=Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase.
|title=Genetic associations with age of menopause in familial longevity.
|date=28.03.2018
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397389
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://sci-hub.do/10.1515/revneuro-2017-0049
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==PIM1==
==TOMM20==


* {{medline-title
* {{medline-title
|title=[[PIM1]]-catalyzed [[CBX8]] phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast.
|title=Effect of aging on mitochondria and metabolism of bovine granulosa cells.
|date=27.06.2018
|date=13.09.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29763603
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32921645
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.05.070
|full-text-url=https://sci-hub.do/10.1262/jrd.2020-071
}}
}}
==CHAT==
==TOP1==


* {{medline-title
* {{medline-title
|title=Satisfaction and Technology Evaluation of a Telehealth Robotic Program to Optimize Healthy Independent Living for Older Adults.
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|date=11.2018
|date=12.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30320967
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|full-text-url=https://sci-hub.do/10.1111/jnu.12436
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
}}
}}
==EIF2B5==
==TOR2A==


* {{medline-title
* {{medline-title
|title=Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of [[CSF1R]] and [[NOTCH3]].
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
|date=06.2018
|date=05.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544907
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937905
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
}}
}}
==RAD9A==
==TP53INP1==


* {{medline-title
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|title=[[TP53INP1]] deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling.
|date=02.2018
|date=02.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30559202
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320535
}}
}}
==TRPS1==
==TP53RK==


* {{medline-title
* {{medline-title
|title=miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence.
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|date=01.2020
|date=11.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074095
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|full-text-url=https://sci-hub.do/10.1002/jcb.28862
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
}}
}}
==RIF1==
==TP73==


* {{medline-title
* {{medline-title
|title=53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
|title=G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
|date=02.01.2020
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31653568
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28912086
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944352
}}
}}
==DAP==
==TPH1==


* {{medline-title
* {{medline-title
|title=Examining changes in the equity of physician distribution in Japan: a specialty-specific longitudinal study.
|title=[i]Lactobacillus plantarum[/i] DR7 improved brain health in aging rats via the serotonin, inflammatory and apoptosis pathways.
|date=08.01.2018
|date=02.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29317415
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33245015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5781009
|full-text-url=https://sci-hub.do/10.3920/BM2019.0200
}}
}}
==GATA6==
==TPP1==


* {{medline-title
* {{medline-title
|title=GATA Regulation and Function During the Ovarian Life Cycle.
|title=FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping.
|date=2018
|date=03.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29544631
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33086033
|full-text-url=https://sci-hub.do/10.1016/bs.vh.2018.01.014
|full-text-url=https://sci-hub.do/10.1016/j.cmet.2020.10.004
}}
}}
==DUT==
==TPRKB==


* {{medline-title
* {{medline-title
|title=Simultaneous liquefaction, saccharification, and fermentation of L-lactic acid using aging paddy rice with hull by an isolated thermotolerant Enterococcus faecalis [[DUT]]1805.
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|date=09.2020
|date=11.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32388689
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|full-text-url=https://sci-hub.do/10.1007/s00449-020-02364-y
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
}}
}}
==ANXA1==
==TPX2==


* {{medline-title
* {{medline-title
|title=Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging.
|title=Targeting [[DTL]] induces cell cycle arrest and senescence and suppresses cell growth and colony formation through [[TPX2]] inhibition in human hepatocellular carcinoma cells.
|date=26.10.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30373163
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29606879
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274848
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868578
}}
}}
==ADORA2B==
==TRAF2==


* {{medline-title
* {{medline-title
|title=Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss.
|title=The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium.
|date=12.2020
|date=12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33131093
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31042012
|full-text-url=https://sci-hub.do/10.1096/fj.202000939R
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711781
}}
}}
==LAMA5==
==TRAP1==


* {{medline-title
* {{medline-title
|title=The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese.
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|date=05.06.2018
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29883365
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
}}
}}
==LYG1==
==TRAV1-2==


* {{medline-title
* {{medline-title
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|title=Human blood MAIT cell subsets defined using [[MR1]] tetramers.
|date=03.2019
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29437263
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446826
}}
}}
==TET3==
==TRAV27==


* {{medline-title
* {{medline-title
|title=Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
|title=Perturbed CD8  T cell immunity across universal influenza epitopes in the elderly.
|date=02.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30868493
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928269
|full-text-url=https://sci-hub.do/10.1007/s11596-019-2001-y
|full-text-url=https://sci-hub.do/10.1189/jlb.5MA0517-207R
}}
}}
==MARCKS==
==TRBV19==


* {{medline-title
* {{medline-title
|title=Ser46-Phosphorylated [[MARCKS]] Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology.
|title=Perturbed CD8  T cell immunity across universal influenza epitopes in the elderly.
|date=07-08.2018
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30225354
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28928269
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140116
|full-text-url=https://sci-hub.do/10.1189/jlb.5MA0517-207R
}}
}}
==PIK3R1==
==TRIB2==


* {{medline-title
* {{medline-title
|title=Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
|title=[[TRIB2]] functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling.
|date=08.10.2018
|date=12.12.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29300832
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175033
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291992
}}
}}
==GJA8==
==TRIB3==


* {{medline-title
* {{medline-title
|title=The impact of [[GJA8]] SNPs on susceptibility to age-related cataract.
|title=Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy.
|date=12.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30349978
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30025493
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267713
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152528
}}
}}
==CHRNA7==
==TRIM21==


* {{medline-title
* {{medline-title
|title=Associations between genetic variations and global motion perception.
|title=[[TRIM21]] overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma.
|date=10.2019
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31432227
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32064156
|full-text-url=https://sci-hub.do/10.1007/s00221-019-05627-7
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017742
}}
}}
==LDB2==
==TRIM27==


* {{medline-title
* {{medline-title
|title=Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.
|title=[[TRIM27]] Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination.
|date=11.2017
|date=04.12.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28841467
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33251042
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2017.07.015
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666371
}}
}}
==WNT3==
==TRIM28==


* {{medline-title
* {{medline-title
|title=Role of CD133 Molecule in Wnt Response and Renal Repair.
|title=Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau.
|date=03.2018
|date=04.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29431914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29863470
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827750
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993537
}}
}}
==CDX2==
==TRIP13==


* {{medline-title
* {{medline-title
|title=Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice.
|title=BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.
|date=08.07.2019
|date=02.01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31174209
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31738183
|full-text-url=https://sci-hub.do/10.1093/humrep/dez054
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934189
}}
}}
==RIMS2==
==TRPC1==


* {{medline-title
* {{medline-title
|title=Age-related gene and miRNA expression changes in airways of healthy individuals.
|title=Ca  entry via [[TRPC1]] is essential for cellular differentiation and modulates secretion via the SNARE complex.
|date=06.03.2019
|date=01.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30842487
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31182642
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633397
}}
}}
==P4HA2==
==TRPC7==


* {{medline-title
* {{medline-title
|title=Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients.
|title=Nociceptive transient receptor potential canonical 7 ([[TRPC7]]) mediates aging-associated tumorigenesis induced by ultraviolet B.
|date=03.09.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31560770
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31755176
|full-text-url=https://sci-hub.do/10.1167/iovs.19-27921
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974716
}}
}}
==SLC30A10==
==TRPM6==


* {{medline-title
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|title=Role of kinase-coupled TRP channels in mineral homeostasis.
|date=01.12.2017
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129644
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
|full-text-url=https://sci-hub.do/10.1016/j.pharmthera.2017.11.003
}}
}}
==ERAP1==
==TRPS1==


* {{medline-title
* {{medline-title
|title=Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength.
|title=miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence.
|date=10.2019
|date=01.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31254144
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31074095
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733812
|full-text-url=https://sci-hub.do/10.1002/jcb.28862
}}
}}
==SLC30A5==
==TRPV5==


* {{medline-title
* {{medline-title
|title=Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence.
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|date=01.12.2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28918363
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|full-text-url=https://sci-hub.do/10.1016/j.exger.2017.09.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
}}
}}
==PTPRC==
==TRPV6==


* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=Changes in expression of klotho affect physiological processes, diseases, and cancer.
|date=05.2017
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29372030
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776433
}}
}}
==NPW==
==TSG101==


* {{medline-title
* {{medline-title
|title=Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study.
|title=Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging.
|date=09.2020
|date=01.09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32309980
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31220525
|full-text-url=https://sci-hub.do/10.1037/pag0000468
|full-text-url=https://sci-hub.do/10.1016/j.lfs.2019.116582
}}
}}
==NLRP6==
==TSHB==


* {{medline-title
* {{medline-title
|title=LRP6 targeting suppresses gastric tumorigenesis via P14 -Mdm2-P53-dependent cellular senescence.
|title=Adipose [[TSHB]] in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence.
|date=19.12.2017
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29340077
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30448824
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762345
|full-text-url=https://sci-hub.do/10.1159/000495170
}}
}}
==SCNN1B==
==TSHR==


* {{medline-title
* {{medline-title
|title=Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects.
|title=TSH-independent release of thyroid hormones through cold exposure in aging rats.
|date=18.10.2018
|date=27.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30340375
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29163760
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213100
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685681
}}
}}
==SP2==
==TSPYL5==


* {{medline-title
* {{medline-title
|title=Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography.
|title=Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.
|date=12.2017
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28791483
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30784661
|full-text-url=https://sci-hub.do/10.1007/s00484-017-1415-0
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171
}}
}}
==SESN1==
==TTL==


* {{medline-title
* {{medline-title
|title=Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis.
|title=Longitudinal Associations of Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio with Biomarkers of Oxidative Stress in Older Adults: Results of a Large Cohort Study.
|date=09.2018
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29751091
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31986512
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.05.006
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098284
}}
}}
==ISG15==
==TXN==


* {{medline-title
* {{medline-title
|title=Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood.
|title=Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice.
|date=14.01.2019
|date=15.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30641486
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29141658
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339791
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688691
}}
}}
==RAG2==
==TXNDC5==


* {{medline-title
* {{medline-title
|title=Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation.
|title=Genetic associations with age of menopause in familial longevity.
|date=2020
|date=10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32793218
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31188284
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387685
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937
}}
}}
==ECM1==
==TXNRD1==


* {{medline-title
* {{medline-title
|title=Novel role of extracellular matrix protein 1 ([[ECM1]]) in cardiac aging and myocardial infarction.
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|date=2019
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30789914
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383988
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
}}
}}
==ROS1==
==TYK2==


* {{medline-title
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|title=Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
|date=15.11.2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29454012
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
|full-text-url=https://sci-hub.do/10.1016/j.yrtph.2018.02.006
}}
}}
==TAF7L==
==TYROBP==


* {{medline-title
* {{medline-title
|title=Basonuclin 1 deficiency causes testicular premature aging: [[BNC1]] cooperates with [[TAF7]]L to regulate spermatogenesis.
|title=[[TREM2]] triggers microglial density and age-related neuronal loss.
|date=22.01.2020
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31065688
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30548312
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052986
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590266
}}
}}
==TCERG1==
==U2AF1==


* {{medline-title
* {{medline-title
|title=The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity.
|title=Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs.
|date=17.07.2019
|date=05.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31316054
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32141009
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637209
|full-text-url=https://sci-hub.do/10.1007/s40520-020-01509-z
}}
}}
==RPIA==
==UACA==


* {{medline-title
* {{medline-title
|title=Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming.
|title=Knockdown of [i][[UACA]][/i] inhibitsproliferation and invasion and promotes senescence of hepatocellular carcinoma cells.
|date=20.08.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31433975
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31949867
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716532
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962967
}}
}}
==ACO1==
==UBB==


* {{medline-title
* {{medline-title
|title=Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine.
|title=Different Expression Levels of Human Mutant Ubiquitin B  ([[UBB]] ) Can Modify Chronological Lifespan or Stress Resistance of [i]Saccharomyces cerevisiae[/i].
|date=24.04.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30690072
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29950972
|full-text-url=https://sci-hub.do/10.1016/j.jep.2019.01.019
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008557
}}
}}
==HLA-DRB1==
==UBC==


* {{medline-title
* {{medline-title
|title=The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle.
|title=Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies.
|date=11.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32942037
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30915334
|full-text-url=https://sci-hub.do/10.1016/j.autrev.2020.102670
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421261
}}
}}
==LOXL1==
==UBE2E3==


* {{medline-title
* {{medline-title
|title=A blackberry-dill extract combination synergistically increases skin elasticity.
|title=Loss of the ubiquitin conjugating enzyme [[UBE2E3]] induces cellular senescence.
|date=10.2020
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32583541
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29879550
|full-text-url=https://sci-hub.do/10.1111/ics.12644
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007080
}}
}}
==CYP11B2==
==UBE3A==


* {{medline-title
* {{medline-title
|title=Expression of aldosterone synthase [[CYP11B2]] was inversely correlated with longevity.
|title=Delayed loss of [[UBE3A]] reduces the expression of Angelman syndrome-associated phenotypes.
|date=07.2019
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30974191
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31143434
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786771
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532248
}}
}}
==CDH2==
==UBE4B==


* {{medline-title
* {{medline-title
|title=CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type.
|title=CircRNAs in the tree shrew ([i]Tupaia belangeri[/i]) brain during postnatal development and aging.
|date=30.11.2018
|date=30.04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30102368
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29723158
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265269
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940110
}}
}}
==STX17==
==UBTF==


* {{medline-title
* {{medline-title
|title=Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and [[XIAP]].
|title=Age-associated dysregulation of protein metabolism in the mammalian oocyte.
|date=01.10.2019
|date=12.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31251987
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994181
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2019.05.017
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676066
}}
}}
==CNTNAP2==
==UCHL1==


* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=Abolishing [[UCHL1]]'s hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice.
|date=05.2017
|date=04.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33159930
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://sci-hub.do/10.1016/j.expneurol.2020.113524
}}
}}
==RGS14==
==UCHL3==


* {{medline-title
* {{medline-title
|title=Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14.
|title=[[UCHL3]] Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling [[TDP1]] Proteostasis.
|date=08.2018
|date=12.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29654651
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29898404
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052469
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019701
}}
}}
==RHEBL1==
==UCN==


* {{medline-title
* {{medline-title
|title=Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=03.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29570707
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884551
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==FCER1G==
==UCN3==


* {{medline-title
* {{medline-title
|title=A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks.
|title=Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise-induced threshold shift.
|date=2019
|date=08.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30733664
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31270820
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353788
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852351
}}
}}
==PMS1==
==UCP3==


* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=Integrated study on comparative transcriptome and skeletal muscle function in aged rats.
|date=25.02.2019
|date=01.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29325930
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://sci-hub.do/10.1016/j.mad.2018.01.001
}}
}}
==TXNRD1==
==UGT2B28==


* {{medline-title
* {{medline-title
|title=The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions.
|title=Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a [[UGT2B28]] genomic variation.
|date=06.2018
|date=05.12.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577582
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31805979
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946073
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896495
}}
}}
==ITPR2==
==UGT2B7==


* {{medline-title
* {{medline-title
|title=The nuclear receptor [[RXRA]] controls cellular senescence by regulating calcium signaling.
|title=Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
|date=12.2018
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30216632
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30985942
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260923
|full-text-url=https://sci-hub.do/10.1002/bdd.2181
}}
}}
==KAT6B==
==UHRF1==


* {{medline-title
* {{medline-title
|title=Aging-associated decrease in the histone acetyltransferase [[KAT6B]] is linked to altered hematopoietic stem cell differentiation.
|title=MLL3 promotes the senescence of esophageal squamous cell carcinoma.
|date=02.2020
|date=2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32014431
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30881012
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179256
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402438
}}
}}
==ASB3==
==ULK2==


* {{medline-title
* {{medline-title
|title=Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.
|title=miR-26a suppresses autophagy in swine Sertoli cells by targeting [[ULK2]].
|date=02.2019
|date=08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30585438
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29761550
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818258
|full-text-url=https://sci-hub.do/10.1111/rda.13177
}}
}}
==F12==
==UMOD==


* {{medline-title
* {{medline-title
|title=Multigenerational effects of carbendazim in Daphnia magna: From a subcellular to a population level.
|title=The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes.
|date=02.2019
|date=03.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30508263
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30311395
|full-text-url=https://sci-hub.do/10.1002/etc.4307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368468
}}
==MAL==
 
* {{medline-title
|title=Daylight photodynamic therapy versus cryosurgery for the treatment and prophylaxis of actinic keratoses of the face - protocol of a multicenter, prospective, randomized, controlled, two-armed study.
|date=25.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29070025
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657041
}}
==CEBPB==
 
* {{medline-title
|title=Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29875655
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974201
}}
}}
==UNG==
==UNG==
Строка 13 503: Строка 13 351:
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931555
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931555
}}
}}
==PHB2==
==UPF1==


* {{medline-title
* {{medline-title
|title=Prohibitin-2 is a novel regulator of p21  induced by depletion of γ-glutamylcyclotransferase.
|title=Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity.
|date=29.01.2018
|date=21.08.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29307834
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28824175
|full-text-url=https://sci-hub.do/10.1016/j.bbrc.2018.01.029
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563511
}}
}}
==DBT==
==UQCRC2==


* {{medline-title
* {{medline-title
|title=Diurnal rhythms of heart and respiratory rates in donkeys of different age groups during the cold-dry and hot-dry seasons in a tropical savannah.
|title=Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10).
|date=09.2018
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30187687
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477336
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125241
|full-text-url=https://sci-hub.do/10.1016/j.exger.2018.02.025
}}
}}
==SUGCT==
==USF1==


* {{medline-title
* {{medline-title
|title=Knockout of the non-essential gene [[SUGCT]] creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype.
|title=The rs2516839 variation of [[USF1]] gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+ study.
|date=09.2020
|date=01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31722069
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30203836
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426296
|full-text-url=https://sci-hub.do/10.1111/ahg.12282
}}
}}
==HK2==
==USF2==


* {{medline-title
* {{medline-title
|title=Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury.
|title=Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice.
|date=11.01.2018
|date=15.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29326403
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30084918
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811244
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454504
}}
}}
==ATP1A2==
==USP14==


* {{medline-title
* {{medline-title
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|title=Low expression of aging-related [[[[NRXN3]]]] is associated with Alzheimer disease: A systematic review and meta-analysis.
|date=04.07.2019
|date=07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29995770
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076205
}}
}}
==ITGA6==
==USP15==


* {{medline-title
* {{medline-title
|title=Selective molecular biomarkers to predict biologic behavior in pituitary tumors.
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i].
|date=05.2017
|date=29.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30063456
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156
|full-text-url=https://sci-hub.do/10.1080/17446651.2017.1312341
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047
}}
}}
==EDF1==
==USP28==


* {{medline-title
* {{medline-title
|title=Silencing of FOREVER YOUNG FLOWER Like Genes from Phalaenopsis Orchids Promotes Flower Senescence and Abscission.
|title=Genetic interrogation of replicative senescence uncovers a dual role for [[USP28]] in coordinating the p53 and [[GATA4]] branches of the senescence program.
|date=25.11.2020
|date=01.10.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33237274
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29089421
|full-text-url=https://sci-hub.do/10.1093/pcp/pcaa145
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710139
}}
}}
==DOT1L==
==USP30==


* {{medline-title
* {{medline-title
|title=Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction.
|title=Deficiency of parkin and [[PINK1]] impairs age-dependent mitophagy in [i]Drosophila[/i].
|date=04.2018
|date=29.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29366775
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29809156
|full-text-url=https://sci-hub.do/10.1016/j.bbadis.2018.01.018
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008047
}}
}}
==DAXX==
==USP7==


* {{medline-title
* {{medline-title
|title=[[ATRX]]-[[DAXX]] Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains.
|title=Deubiquitinase [[USP7]] regulates [i]Drosophila[/i] aging through ubiquitination and autophagy.
|date=09.2019
|date=20.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31361513
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33221768
|full-text-url=https://sci-hub.do/10.1089/dna.2019.4752
|full-text-url=https://sci-hub.do/10.18632/aging.104067
}}
}}
==GLO1==
==USP8==


* {{medline-title
* {{medline-title
|title=The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases.
|title=Inhibition of the deubiquitinase [[USP8]] corrects a Drosophila [[PINK1]] model of mitochondria dysfunction.
|date=2017
|date=04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29259621
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988163
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723304
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467245
}}
}}
==S100A6==
==VAMP2==


* {{medline-title
* {{medline-title
|title=Sex differences in distribution of cannabinoid receptors (CB1 and CB2), [[S100A6]] and CacyBP/SIP in human ageing hearts.
|title=Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission.
|date=27.11.2018
|date=01.08.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30482253
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29950309
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258148
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068464
}}
}}
==PGM1==
==VAMP8==


* {{medline-title
* {{medline-title
|title=Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle.
|title=[[NUPR1]] maintains autolysosomal efflux by activating [[SNAP25]] transcription in cancer cells.
|date=15.05.2019
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30862562
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29130426
|full-text-url=https://sci-hub.do/10.1016/j.jprot.2019.03.004
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959327
}}
}}
==TARDBP==
==VASH1==


* {{medline-title
* {{medline-title
|title=Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.
|title=Double-Face of Vasohibin-1 for the Maintenance of Vascular Homeostasis and Healthy Longevity.
|date=06.2018
|date=01.06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29577934
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29398681
|full-text-url=https://sci-hub.do/10.1016/j.ajpath.2018.03.002
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005230
}}
}}
==ANKS1B==
==VASP==


* {{medline-title
* {{medline-title
|title=Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.
|title=Reversal of Aging-Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein-Protein Interfaces.
|date=01.2018
|date=18.07.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29027019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30021807
|full-text-url=https://sci-hub.do/10.1007/s00702-017-1796-6
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201469
}}
}}
==DNM1==
==VCL==


* {{medline-title
* {{medline-title
|title=Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice.
|title=The effects of different preservation methods on ide (Leuciscus idus) sperm and the longevity of sperm movement.
|date=2018
|date=04.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29503614
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29397922
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820363
|full-text-url=https://sci-hub.do/10.1016/j.cryobiol.2018.01.014
}}
}}
==LYST==
==VCP==


* {{medline-title
* {{medline-title
|title=Whole-Exome Sequencing of an Exceptional Longevity Cohort.
|title=The role of air pollution and lung function in cognitive impairment.
|date=16.08.2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29750252
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29467204
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723
|full-text-url=https://sci-hub.do/10.1183/13993003.01963-2017
}}
}}
==GFRAL==
==VEGFA==


* {{medline-title
* {{medline-title
|title=Growth differentiation factor 15 ([[GDF15]]): A survival protein with therapeutic potential in metabolic diseases.
|title=APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease.
|date=06.2019
|date=03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30790643
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31791659
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196666
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064375
}}
}}
==UHRF1==
==VEGFC==


* {{medline-title
* {{medline-title
|title=MLL3 promotes the senescence of esophageal squamous cell carcinoma.
|title=Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs.
|date=2019
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30881012
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29080277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402438
|full-text-url=https://sci-hub.do/10.1111/rda.13091
}}
}}
==COQ9==
==VEGFD==


* {{medline-title
* {{medline-title
|title=Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.
|title=Single-Arm Resistance Training Study to Determine the Relationship between Training Outcomes and Muscle Growth Factor mRNAs in Older Adults Consuming Numerous Medications and Supplements.
|date=18.09.2018
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30228311
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29380855
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143522
|full-text-url=https://sci-hub.do/10.1007/s12603-017-0913-4
}}
}}
==SLC52A2==
==VGLL4==


* {{medline-title
* {{medline-title
|title=Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.
|title=The lncRNA MEG3/miR-16-5p/[[VGLL4]] regulatory axis is involved in etoposide-induced senescence of tumor cells.
|date=01.11.2017
|date=03.11.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29053833
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33141998
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808726
|full-text-url=https://sci-hub.do/10.1002/jgm.3291
}}
}}
==PRDM8==
==VHLL==


* {{medline-title
* {{medline-title
|title=[[PRDM8]] reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation.
|title=The Monetary Valuation of Lifetime Health Improvement and Life Expectancy Gains in Turkey.
|date=20.08.2020
|date=29.09.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32819411
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28961227
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439574
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664652
}}
}}
==F10==
==VIPR2==


* {{medline-title
* {{medline-title
|title=Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-[[F10]] cells by inducing senescence.
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.07.2018
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30097108
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.06.008
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
}}
==DNM2==
==VPREB3==


* {{medline-title
* {{medline-title
|title=Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy.
|title=Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans.
|date=19.11.2018
|date=19.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30451843
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30541985
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243013
|full-text-url=https://sci-hub.do/10.1266/ggs.17-00052
}}
}}
==PSAP==
==VPS13C==


* {{medline-title
* {{medline-title
|title=Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=08.2018
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29656342
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://sci-hub.do/10.1007/s00441-018-2835-9
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==TRIM21==
==VPS13D==


* {{medline-title
* {{medline-title
|title=[[TRIM21]] overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma.
|title=SerThr-PhosphoProteome of Brain from Aged [[PINK1]]-KO+A53T-[[SNCA]] Mice Reveals pT1928-[[MAP1B]] and pS3781-[[ANK2]] Deficits, as Hub between Autophagy and Synapse Changes.
|date=2020
|date=04.07.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32064156
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31277379
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017742
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651490
}}
}}
==TMEM119==
==VPS29==


* {{medline-title
* {{medline-title
|title=Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia.
|title=Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development.
|date=02.2019
|date=16.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29948944
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654520
|full-text-url=https://sci-hub.do/10.1007/s12035-018-1156-z
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359594
}}
}}
==CDC6==
==VPS35==


* {{medline-title
* {{medline-title
|title=A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.
|title=Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development.
|date=10.01.2018
|date=16.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29321003
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30654520
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763532
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359594
}}
}}
==RPL11==
==VSIG4==


* {{medline-title
* {{medline-title
|title=[[NOL12]] Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.
|title=Immune checkpoint protein [[VSIG4]] as a biomarker of aging in murine adipose tissue.
|date=15.06.2019
|date=10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30988155
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32856419
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549468
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7576241
}}
}}
==EED==
==WAS==


* {{medline-title
* {{medline-title
|title=Economic evaluations of eHealth technologies: A systematic review.
|title=Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number.
|date=2018
|date=09.11.2017
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29897921
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29129830
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999277
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723686
}}
}}
==PAX1==
==WASL==


* {{medline-title
* {{medline-title
|title=Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence.
|title=Loss of Wasl improves pancreatic cancer outcome.
|date=26.06.2018
|date=21.05.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29941029
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32434991
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259520
}}
}}
==FER1L6==
==WDR5==


* {{medline-title
* {{medline-title
|title=Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle.
|title=Inhibition of the H3K4 methyltransferase MLL1/[[WDR5]] complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16 .
|date=12.2017
|date=11.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28994157
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31570196
|full-text-url=https://sci-hub.do/10.1111/jbg.12299
|full-text-url=https://sci-hub.do/10.1016/j.kint.2019.06.021
}}
}}
==KDM5A==
==WDR73==


* {{medline-title
* {{medline-title
|title=Structure-Based Discovery of a Selective [[KDM5A]] Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines.
|title=Novel homozygous [[OSGEP]] gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature.
|date=15.01.2019
|date=11.04.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30650517
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30975089
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360022
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458604
}}
}}
==CYP11B1==
==WFDC2==


* {{medline-title
* {{medline-title
|title=Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼.
|title=Differences in biomarkers and molecular pathways according to age for patients with HFrEF.
|date=11.2020
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002589
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33002110
|full-text-url=https://sci-hub.do/10.1016/j.jsbmb.2020.105764
|full-text-url=https://sci-hub.do/10.1093/cvr/cvaa279
}}
==WFIKKN1==
 
* {{medline-title
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.
|date=01.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188
}}
==WFIKKN2==
 
* {{medline-title
|title=Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults.
|date=01.01.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30380014
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298188
}}
}}
==ALAS1==
==WLS==


* {{medline-title
* {{medline-title
|title=Heterozygous disruption of [[ALAS1]] in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver.
|title=Evaluation of three statistical prediction models for forensic age prediction based on DNA methylation.
|date=08.12.2020
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/33307066
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29477092
|full-text-url=https://sci-hub.do/10.1016/j.abb.2020.108721
|full-text-url=https://sci-hub.do/10.1016/j.fsigen.2018.02.008
}}
}}
==TRAP1==
==WNK1==


* {{medline-title
* {{medline-title
|title=Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2.
|date=2019
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30837897
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4
}}
}}
==ASIP==
==WNK4==


* {{medline-title
* {{medline-title
|title=Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation.
|title=Overexpression of [[WNK1]] in [[POMC]]-expressing neurons reduces weigh gain via [[WNK4]]-mediated degradation of Kir6.2.
|date=10.2018
|date=10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30222197
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29392534
|full-text-url=https://sci-hub.do/10.1111/ics.12494
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3301-4
}}
}}
==MSH2==
==WNT10A==


* {{medline-title
* {{medline-title
|title=RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells.
|title=Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development.
|date=25.02.2019
|date=01.04.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30805972
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31964233
|full-text-url=https://sci-hub.do/10.1002/jcb.28417
|full-text-url=https://sci-hub.do/10.1089/scd.2019.0260
}}
}}
==SMC3==
==WNT16==


* {{medline-title
* {{medline-title
|title=Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice.
|title=Inducible [i]Wnt16[/i] inactivation: [[WNT16]] regulates cortical bone thickness in adult mice.
|date=10.2018
|date=05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29667147
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29530924
|full-text-url=https://sci-hub.do/10.1007/s11655-018-2835-3
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886037
}}
}}
==RNF168==
==WNT3==


* {{medline-title
* {{medline-title
|title=[[PML]] nuclear bodies are recruited to persistent DNA damage lesions in an [[RNF168]]-53BP1 dependent manner and contribute to DNA repair.
|title=Role of CD133 Molecule in Wnt Response and Renal Repair.
|date=06.2019
|date=03.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31009828
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29431914
|full-text-url=https://sci-hub.do/10.1016/j.dnarep.2019.04.001
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827750
}}
==WNT5A==
 
* {{medline-title
|title=[[WNT5A]] supports viability of senescent human dental follicle cells.
|date=05.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30406314
|full-text-url=https://sci-hub.do/10.1007/s11010-018-3467-9
}}
==WNT7A==
 
* {{medline-title
|title=Exogenous Expression of [[WNT7A]] in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents.
|date=2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32436833
|full-text-url=https://sci-hub.do/10.2174/1871520620666200521114100
}}
==WT1==
 
* {{medline-title
|title=Age and weight at first mating affects plasma leptin concentration but no effects on reproductive performance of gilts.
|date=09.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31602307
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778857
}}
==WWP1==
 
* {{medline-title
|title=The ubiquitin ligase [[WWP1]] contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart.
|date=01.10.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32822210
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717125
}}
==XDH==
 
* {{medline-title
|title=Enhancing xanthine dehydrogenase activity is an effective way to delay leaf senescence and increase rice yield.
|date=11.03.2020
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/32162142
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065298
}}
==XG==
 
* {{medline-title
|title=The effect of administration media on palatability and ease of swallowing of multiparticulate formulations.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30170024
|full-text-url=https://sci-hub.do/10.1016/j.ijpharm.2018.08.021
}}
==XPC==
 
* {{medline-title
|title=MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene [[XPC]] in Age-related Cataract.
|date=12.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30315181
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185952
}}
==XPO1==
 
* {{medline-title
|title=Nuclear Export Inhibition Enhances HLH-30/[[TFEB]] Activity, Autophagy, and Lifespan.
|date=15.05.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29768192
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991088
}}
==XRCC4==
 
* {{medline-title
|title=The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.
|date=2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30008586
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081
}}
==YES1==
 
* {{medline-title
|title=Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies.
|date=20.10.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30341976
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224233
}}
==ZBTB16==
 
* {{medline-title
|title=miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells.
|date=06.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29171024
|full-text-url=https://sci-hub.do/10.1002/jcp.26231
}}
==ZFHX3==
 
* {{medline-title
|title=Shift work, DNA methylation and epigenetic age.
|date=01.10.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30879037
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857743
}}
==ZFPM2==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==ZNF207==
 
* {{medline-title
|title=Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
|date=02.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29196338
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795392
}}
==ZNF396==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==ZNF467==
 
* {{medline-title
|title=Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology.
|date=15.11.2018
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/30466987
|full-text-url=https://sci-hub.do/10.1016/j.phymed.2018.09.204
}}
==ZNF521==
 
* {{medline-title
|title=Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells.
|date=21.06.2019
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/31227697
|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588633
}}
}}

Версия от 14:39, 31 марта 2021

ABCA1

  • Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension. / 01.07.2019 / PubMed / Full text
  • Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. / 08.2018 / PubMed / Full text

ACACA

  • Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text
  • GH prevents adipogenic differentiation of mesenchymal stromal stem cells derived from human trabecular bone via canonical Wnt signaling. / 07.2018 / PubMed / Full text

ACAT1

  • An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. / 06.2019 / PubMed / Full text
  • Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. / 15.12.2017 / PubMed / Full text

ACOX1

  • Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes. / 04.2019 / PubMed / Full text
  • Peroxisomal Acyl-CoA Oxidase Type 1: Anti-Inflammatory and Anti-Aging Properties with a Special Emphasis on Studies with LPS and Argan Oil as a Model Transposable to Aging. / 2018 / PubMed / Full text

ACTA1

  • Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. / 15.05.2019 / PubMed / Full text
  • Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. / 15.12.2017 / PubMed / Full text

ACTB

  • Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text
  • WNT-activated bone grafts repair osteonecrotic lesions in aged animals. / 27.10.2017 / PubMed / Full text

ADAM17

  • ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19. / 2020 / PubMed / Full text
  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

ADH5

  • Can Serum Nitrosoproteome Predict Longevity of Aged Women? / 27.11.2020 / PubMed / Full text
  • Denitrosylate and live longer: how ADH5/GSNOR links mitophagy to aging. / 2018 / PubMed / Full text

AGER

  • Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model. / 01.10.2019 / PubMed / Full text
  • Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. / 03.2018 / PubMed / Full text

AGO2

  • Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. / 06.2018 / PubMed / Full text
  • miRNA processing gene polymorphisms, blood DNA methylation age and long-term ambient PM exposure in elderly men. / 12.2017 / PubMed / Full text

AGT

  • SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence. / 06.2020 / PubMed / Full text
  • Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text

ALKBH8

  • Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming . / 01.2020 / PubMed / Full text
  • ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed

AMT

  • A multi-method comparison of autobiographical memory impairments amongst younger and older adults. / 12.03.2020 / PubMed / Full text
  • Autobiographical Memory From Different Life Stages in Individuals With Obstructive Sleep Apnea. / 03.2019 / PubMed / Full text

ANGPTL2

  • Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study. / 01.05.2020 / PubMed / Full text
  • Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice. / 02.02.2018 / PubMed / Full text

ANK1

  • Alzheimer's Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in [i]Drosophila[/i]. / 2019 / PubMed / Full text
  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

APOA5

  • Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency. / 03.2019 / PubMed / Full text
  • Longitudinal interaction between APOA5 -1131T>C and overweight in the acceleration of age-related increase in arterial stiffness through the regulation of circulating triglycerides. / 02.2019 / PubMed / Full text

APPL2

  • The reversal effect of physical exercise on aging-related increases in APPL2 content in skeletal muscle. / 01.10.2018 / PubMed / Full text
  • Adaptor Protein APPL2 Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor. / 07.2018 / PubMed / Full text

AQP1

  • Blue Light Induces Down-Regulation of Aquaporin 1, 3, and 9 in Human Keratinocytes. / 03.11.2018 / PubMed / Full text
  • [Age-related changes of water transport by corneal endothelial cells in rats.] / 2017 / PubMed

AQP3

  • Transbuccal platform for delivery of lipogenic actives to facial skin: Because fat matters. / 08.2020 / PubMed / Full text
  • [Age-related changes of water transport by corneal endothelial cells in rats.] / 2017 / PubMed

AREG

  • Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. / 12.2019 / PubMed / Full text
  • Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text

ARID1A

  • Oncogenic mutations in histologically normal endometrium: the new normal? / 10.2019 / PubMed / Full text
  • ARID1A suppresses malignant transformation of human pancreatic cells via mediating senescence-associated miR-503/[[CDKN2A]] regulatory axis. / 18.11.2017 / PubMed / Full text

ATG12

  • Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text
  • SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

ATG3

  • Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells. / 01.04.2020 / PubMed / Full text
  • SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

ATG9A

  • SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy. / 08.2019 / PubMed / Full text
  • Activation of miR-34a impairs autophagic flux and promotes cochlear cell death via repressing ATG9A: implications for age-related hearing loss. / 05.10.2017 / PubMed / Full text

ATP7A

  • Adipocyte-specific disruption of ATPase copper transporting α in mice accelerates lipoatrophy. / 12.2019 / PubMed / Full text
  • TAp73 regulates ATP7A: possible implications for ageing-related diseases. / 08.12.2018 / PubMed / Full text

B2M

  • The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. / 03.2019 / PubMed / Full text
  • Association between serum β2-microglobulin levels and frailty in an elderly Chinese population: results from RuLAS. / 2017 / PubMed / Full text

B4GALT1

  • Expression of β-1,4-galactosyltransferases during Aging in Caenorhabditis elegans. / 2020 / PubMed / Full text
  • Glycobiology of Aging. / 2018 / PubMed / Full text

BAK1

  • Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon. / 23.09.2020 / PubMed / Full text
  • SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

BCL6

  • Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation. / 01.07.2020 / PubMed / Full text
  • Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text

BECN1

  • Calpain-dependent Beclin1 cleavage stimulates senescence-associated cell death in HT22 hippocampal cells under the oxidative stress conditions. / 14.05.2019 / PubMed / Full text
  • Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-ULK1 signaling pathway. / 04.2018 / PubMed / Full text

BGN

  • Alterations of local functional connectivity in lifespan: A resting-state fMRI study. / 07.2020 / PubMed / Full text
  • Exploring variability in basal ganglia connectivity with functional MRI in healthy aging. / 12.2018 / PubMed / Full text

BIN1

  • Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice. / 20.03.2019 / PubMed / Full text
  • Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text

BMF

  • lncRNA-ES3/miR-34c-5p/BMF axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs. / 17.01.2019 / PubMed / Full text
  • Aging, hematopoiesis, and the myelodysplastic syndromes. / 08.12.2017 / PubMed / Full text

BMP15

  • Antioxidant hesperetin improves the quality of porcine oocytes during aging in vitro. / 01.2019 / PubMed / Full text
  • Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. / 18.10.2017 / PubMed / Full text

BNIP3

  • Late life maintenance and enhancement of functional exercise capacity in low and high responding rats after low intensity treadmill training. / 01.10.2019 / PubMed / Full text
  • Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training. / 01.10.2018 / PubMed / Full text

BTK

  • Amelioration of age-related brain function decline by Bruton's tyrosine kinase inhibition. / 01.2020 / PubMed / Full text
  • BTK suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling. / 22.08.2017 / PubMed / Full text

C9orf72

  • Carriership of two copies of C9orf72 hexanucleotide repeat intermediate-length alleles is a risk factor for ALS in the Finnish population. / 09.11.2020 / PubMed / Full text
  • C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in [i]Drosophila[/i] Glutamatergic Neurons. / 29.08.2018 / PubMed / Full text

CAST

  • Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance. / 05.11.2018 / PubMed / Full text
  • Short Telomeres Induce p53 and Autophagy and Modulate Age-Associated Changes in Cardiac Progenitor Cell Fate. / 06.2018 / PubMed / Full text

CBL

  • Effects of cerebrolysin on nerve growth factor system in the aging rat brain. / 2017 / PubMed / Full text
  • Skeletal Muscle CAP Expression Increases after Dietary Restriction and Aerobic Training in Women with a History of Gestational Diabetes. / 2016 / PubMed / Full text

CCL17

  • Aging and chronic high-fat feeding negatively affects kidney size, function, and gene expression in CTRP1-deficient mice. / 21.10.2020 / PubMed / Full text
  • Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. / 21.05.2019 / PubMed / Full text

CCL20

  • p53 and p53-related mediators PAI-1 and IGFBP-3 are downregulated in peripheral blood mononuclear cells of HIV-patients exposed to non-nucleoside reverse transcriptase inhibitors. / 06.2020 / PubMed / Full text
  • Effects of the Consumption of Milk Biofortified with Selenium, Vitamin E, and Different Fatty Acid Profile on Immune Response in the Elderly. / 02.2018 / PubMed / Full text

CCL21

  • CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults. / 26.03.2019 / PubMed / Full text
  • Changes in expression of klotho affect physiological processes, diseases, and cancer. / 01.2018 / PubMed / Full text

CCL24

  • Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text
  • Anserine/Carnosine Supplementation Suppresses the Expression of the Inflammatory Chemokine CCL24 in Peripheral Blood Mononuclear Cells from Elderly People. / 31.10.2017 / PubMed / Full text

CCN3

  • CCN3 Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta. / 2020 / PubMed / Full text
  • CCN3 (NOV) Drives Degradative Changes in Aging Articular Cartilage. / 13.10.2020 / PubMed / Full text

CCNG2

  • A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. / 2018 / PubMed / Full text
  • Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text

CCR6

  • Age-associated antigen-presenting cell alterations promote dry-eye inducing Th1 cells. / 07.2019 / PubMed / Full text
  • Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text

CD22

  • CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. / 04.2019 / PubMed / Full text
  • Age-related changes in mRNA expression of selected surface receptors in lymphocytes of dairy calves. / 03.2018 / PubMed / Full text

CDK1

  • MicroRNAomic Transcriptomic Analysis Reveal Deregulation of Clustered Cellular Functions in Human Mesenchymal Stem Cells During in Vitro Passaging. / 02.2020 / PubMed / Full text
  • Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells. / 2018 / PubMed / Full text

CDKN2B

  • Molecular Genetics and Functional Analysis Implicate [i]CDKN2BAS1-CDKN2B[/i] Involvement in POAG Pathogenesis. / 21.08.2020 / PubMed / Full text
  • Interference of the long noncoding RNA CDKN2B-AS1 upregulates miR-181a-5p/TGFβI axis to restrain the metastasis and promote apoptosis and senescence of cervical cancer cells. / 04.2019 / PubMed / Full text

CFD

  • Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D. / 07.2019 / PubMed / Full text
  • New horizons in the compression of functional decline. / 01.11.2018 / PubMed / Full text

CHI3L1

  • Postsynaptic damage and microglial activation in AD patients could be linked CXCR4/CXCL12 expression levels. / 15.12.2020 / PubMed / Full text
  • Sex difference in CHI3L1 expression levels in human brain aging and in Alzheimer's disease. / 01.10.2019 / PubMed / Full text

CHM

  • [Molecular regulative mechanisms of aging and interventional effects of Chinese herbal medicine]. / 08.2017 / PubMed / Full text
  • [Molecular mechanisms of autophagy in regulating renal aging and interventional effects of Chinese herbal medicine]. / 11.2016 / PubMed / Full text

CISD2

  • CISD2 Attenuates Inflammation and Regulates Microglia Polarization in EOC Microglial Cells-As a Potential Therapeutic Target for Neurodegenerative Dementia. / 2020 / PubMed / Full text
  • Protective Effects of CISD2 and Influence of Curcumin on CISD2 Expression in Aged Animals and Inflammatory Cell Model. / 25.03.2019 / PubMed / Full text

CLC

  • Impact of Intervention to Improve Nursing Home Resident-Staff Interactions and Engagement. / 13.07.2018 / PubMed / Full text
  • Effect of cholesterol loaded cyclodextrin on semen cryopreservation of Aksaray Malakli shepherd dogs of different ages. / 06.2018 / PubMed / Full text

CLPP

  • Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging. / 02.2019 / PubMed / Full text
  • Mitochondrial unfolded protein response gene Clpp is required to maintain ovarian follicular reserve during aging, for oocyte competence, and development of pre-implantation embryos. / 08.2018 / PubMed / Full text

COL3A1

  • Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season. / 21.12.2019 / PubMed / Full text
  • Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts. / 06.2019 / PubMed / Full text

COPE

  • Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the COPE-study. / 09.04.2020 / PubMed / Full text
  • Falls self-efficacy and falls incidence in community-dwelling older people: the mediating role of coping. / 05.2018 / PubMed / Full text

CPD

  • Reduced proliferation capacity of lung cells in chronic obstructive pulmonary disease. / 05.2019 / PubMed / Full text
  • What Do Clinical Supervisors Require to Teach Residents in Family Medicine How to Care for Seniors? / 03.2018 / PubMed / Full text

CPE

  • Cross-Sectional and Cumulative Longitudinal Central Nervous System Penetration Effectiveness Scores Are Not Associated With Neurocognitive Impairment in a Well Treated Aging Human Immunodeficiency Virus-Positive Population in Switzerland. / 07.2019 / PubMed / Full text
  • COCOA (Theobroma cacao) Polyphenol-Rich Extract Increases the Chronological Lifespan of Saccharomyces cerevisiae. / 2016 / PubMed

CPQ

  • A Spanish Adaptation of the Computer and Mobile Device Proficiency Questionnaires (CPQ and MDPQ) for Older Adults. / 2019 / PubMed / Full text
  • Protective Effect of Semisynthetic and Natural Flavonoid on Aged Rat Microglia-enriched Cultures. / 11.2019 / PubMed / Full text

CRABP2

  • Preconception resveratrol intake against infertility: Friend or foe? / 04.2020 / PubMed / Full text
  • Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females. / 31.10.2017 / PubMed / Full text

CSRP1

  • FOXO3, a Molecular Search for the Fountain of Youth. / 07.03.2019 / PubMed / Full text
  • FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. / 07.03.2019 / PubMed / Full text

CTLA4

  • Horticultural Therapy Reduces Biomarkers of Immunosenescence and Inflammaging in Community-Dwelling Older Adults: A Feasibility Pilot Randomized Controlled Trial. / 18.10.2020 / PubMed / Full text
  • [Efficacy and toxicity of immune checkpoint inhibitors in elderly patients - 5th edition of the congress of pharmacology of anticancer drugs]. / 12.2018 / PubMed / Full text

CXCL11

  • Endothelial cells under therapy-induced senescence secrete CXCL11, which increases aggressiveness of breast cancer cells. / 10.10.2020 / PubMed / Full text
  • Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity. / 13.03.2019 / PubMed / Full text

CXCL5

  • Hassall's corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus. / 05.03.2019 / PubMed / Full text
  • Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age. / 09.2018 / PubMed / Full text

CYLD

  • Premature aging and cancer development in transgenic mice lacking functional CYLD. / 10.01.2019 / PubMed / Full text
  • Pathophysiological significance of cylindromatosis in the vascular endothelium and macrophages for the initiation of age-related atherogenesis. / 22.01.2019 / PubMed / Full text

CYP1A1

  • Genome-wide scan identified genetic variants associated with skin aging in a Chinese female population. / 10.2019 / PubMed / Full text
  • Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells. / 15.12.2018 / PubMed / Full text

CYP1A2

  • Impact of Ethnicity-Specific Hepatic Microsomal Scaling Factor, Liver Weight, and Cytochrome P450 (CYP) 1A2 Content on Physiologically Based Prediction of CYP1A2-Mediated Pharmacokinetics in Young and Elderly Chinese Adults. / 07.2019 / PubMed / Full text
  • Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. / 12.2017 / PubMed / Full text

CYP27B1

  • Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance. / 01.08.2018 / PubMed / Full text
  • Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism. / 22.02.2018 / PubMed / Full text

CYP2D6

  • Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. / 05.2019 / PubMed / Full text
  • [Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug]. / 2018 / PubMed / Full text

CYP3A4

  • Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. / 05.2019 / PubMed / Full text
  • Effect of Age and Allele Variants of CYP3A5, CYP3A4, and POR Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. / 12.2017 / PubMed / Full text

CYP7A1

  • Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of rats. / 2019 / PubMed / Full text
  • Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). / 03.2018 / PubMed / Full text

DAO

  • Age- and gender-dependent D-amino acid oxidase activity in mouse brain and peripheral tissues: implication for aging and neurodegeneration. / 01.08.2019 / PubMed / Full text
  • Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging. / 01.11.2017 / PubMed / Full text

DAPK1

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text
  • Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging. / 05.2019 / PubMed / Full text

DDB1

  • DCAF1 regulates Treg senescence via the ROS axis during immunological aging. / 02.11.2020 / PubMed / Full text
  • Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. / 15.06.2018 / PubMed / Full text

DDX41

  • Salidroside influences the cellular cross-talk of human fetal lung diploid fibroblasts: A proteomic approach. / 03.2018 / PubMed / Full text
  • Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text

DDX58

  • Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood. / 14.01.2019 / PubMed / Full text
  • Age-associated mRNA expression changes in bovine endometrial cells in vitro. / 14.08.2017 / PubMed / Full text

DEGS1

  • [Frailty: Prevalence in the Resident Population of Germany 70 - 79 Years of Age - a Population-Based Approach]. / 11.2017 / PubMed / Full text
  • Physical exercise and cognitive function across the life span: Results of a nationwide population-based study. / 05.2018 / PubMed / Full text

DICER1

  • DICER1: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging. / 2018 / PubMed / Full text
  • Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. / 06.2018 / PubMed / Full text

DISC1

  • Age-Related Changes in Topological Degradation of White Matter Networks and Gene Expression in Chronic Schizophrenia. / 11.2017 / PubMed / Full text
  • Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice. / 19.09.2017 / PubMed / Full text

DKC1

  • Successful liver transplantation in short telomere syndromes without bone marrow failure due to DKC1 mutation. / 05.2020 / PubMed / Full text
  • Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. / 04.2018 / PubMed / Full text

DLX5

  • Inhibition of microRNA-27b-3p relieves osteoarthritis pain via regulation of KDM4B-dependent DLX5. / 09.2020 / PubMed / Full text
  • Detection and evaluation of DNA methylation markers found at SCGN and KLF14 loci to estimate human age. / 11.2017 / PubMed / Full text

DRD3

  • Image-guided phenotyping of ovariectomized mice: altered functional connectivity, cognition, myelination, and dopaminergic functionality. / 02.2019 / PubMed / Full text
  • Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study. / 07.2018 / PubMed / Full text

DSP

  • Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions. / 10.2019 / PubMed / Full text
  • Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. / 05.2018 / PubMed / Full text

DST

  • Ancestral germen/soma distinction in microbes: Expanding the disposable soma theory of aging to all unicellular lineages. / 07.2020 / PubMed / Full text
  • Diet Quality Is Associated With Mortality in Adults Aged 80 Years and Older: A Prospective Study. / 10.2019 / PubMed / Full text

E2F2

  • MicroRNA-31a-5p from aging BMSCs links bone formation and resorption in the aged bone marrow microenvironment. / 08.2018 / PubMed / Full text
  • In situ regeneration of retinal pigment epithelium by gene transfer of E2F2: a potential strategy for treatment of macular degenerations. / 12.2017 / PubMed / Full text

EDARADD

  • Age prediction in living: Forensic epigenetic age estimation based on blood samples. / 11.2020 / PubMed / Full text
  • DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird. / 2017 / PubMed / Full text

EN1

  • Electrochemically detecting DNA methylation in the EN1 gene promoter: implications for understanding ageing and disease. / 27.11.2020 / PubMed / Full text
  • The role of DNA methylation in ageing and cancer. / 11.2018 / PubMed / Full text

ERBB2

  • The biological age linked to oxidative stress modifies breast cancer aggressiveness. / 20.05.2018 / PubMed / Full text
  • Identification of human age-associated gene co-expressions in functional modules using liquid association. / 02.01.2018 / PubMed / Full text

ETS1

  • The transcription factor ETS1 promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1. / 06.12.2019 / PubMed / Full text
  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text

F7

  • The Pattern of Mu Rhythm Modulation During Emotional Destination Memory: Comparison Between Mild Cognitive Impairment Patients and Healthy Controls. / 2019 / PubMed / Full text
  • High levels of incidental physical activity are positively associated with cognition and EEG activity in aging. / 2018 / PubMed / Full text

FAAH

  • Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice. / 02.2020 / PubMed / Full text
  • Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. / 05.2019 / PubMed / Full text

FABP4

  • Senescence Alters PPARγ (Peroxisome Proliferator-Activated Receptor Gamma)-Dependent Fatty Acid Handling in Human Adipose Tissue Microvascular Endothelial Cells and Favors Inflammation. / 05.2018 / PubMed / Full text
  • Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects. / 13.09.2017 / PubMed / Full text

FANCD2

FGFR4

  • FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. / 14.10.2020 / PubMed / Full text
  • The Klotho proteins in health and disease. / 01.2019 / PubMed / Full text

FHL2

  • Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text
  • DNA methylation of the ELOVL2, FHL2, KLF14, C1orf132/MIR29B2C, and TRIM59 genes for age prediction from blood, saliva, and buccal swab samples. / 01.2019 / PubMed / Full text

FLT1

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
  • Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. / 08.10.2018 / PubMed / Full text

FN1

  • Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. / 22.07.2019 / PubMed / Full text
  • Effects of Fibronectin 1 on Cell Proliferation, Senescence and Apoptosis of Human Glioma Cells Through the PI3K/AKT Signaling Pathway. / 2018 / PubMed / Full text

FOXA1

  • Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer. / 28.09.2019 / PubMed / Full text
  • The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. / 05.06.2018 / PubMed / Full text

FOXF1

  • Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence. / 17.08.2018 / PubMed / Full text
  • Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text

FOXP3

  • Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text
  • Enhanced expression of PD-1 and other activation markers by CD4+ T cells of young but not old patients with metastatic melanoma. / 06.2018 / PubMed / Full text

FSTL3

  • Activin type II receptor signaling in cardiac aging and heart failure. / 06.03.2019 / PubMed / Full text
  • Physiology of Activins/Follistatins: Associations With Metabolic and Anthropometric Variables and Response to Exercise. / 01.10.2018 / PubMed / Full text

FUNDC1

  • Mitochondria organize the cellular proteostatic response and promote cellular senescence. / 15.03.2019 / PubMed / Full text
  • A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. / 01.02.2019 / PubMed / Full text

GALT

  • Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life. / 03.2019 / PubMed / Full text
  • Dietary Animal Plasma Proteins Improve the Intestinal Immune Response in Senescent Mice. / 11.12.2017 / PubMed / Full text

GAS6

  • Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. / 2019 / PubMed / Full text
  • Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. / 2017 / PubMed / Full text

GATA2

  • GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice. / 04.2019 / PubMed / Full text
  • Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text

GATA3

  • An imbalance in the T-helper phenotypes displayed by senescent CD4 CD28 T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus. / 11.2018 / PubMed / Full text
  • Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland. / 12.2018 / PubMed / Full text

GDF3

  • In vivo GDF3 administration abrogates aging related muscle regeneration delay following acute sterile injury. / 10.2018 / PubMed / Full text
  • Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. / 05.10.2017 / PubMed / Full text

GIT2

  • Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories. / 12.2019 / PubMed / Full text
  • GIT2-A keystone in ageing and age-related disease. / 05.2018 / PubMed / Full text

GK

  • Progression of diabetic kidney disease in T2DN rats. / 01.12.2019 / PubMed / Full text
  • Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging. / 04.2019 / PubMed / Full text

GLS

  • Normal Values and Growth-Related Changes of Left Ventricular Volumes, Stress, and Strain in Healthy Children Measured by 3-Dimensional Echocardiography. / 15.07.2018 / PubMed / Full text
  • Future Perspectives for Management of Stage A Heart Failure. / 01.07.2018 / PubMed / Full text

GNG3

  • Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text
  • Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text

GNRH1

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
  • Elucidating the genetic architecture of reproductive ageing in the Japanese population. / 17.05.2018 / PubMed / Full text

GPR39

  • Zinc-mediated Neurotransmission in Alzheimer's Disease: A Potential Role of the GPR39 in Dementia. / 2020 / PubMed / Full text
  • GPR39 agonist TC-G 1008 ameliorates IL-1β-induced chondrocyte senescence. / 12.2019 / PubMed / Full text

GPT

  • Brain Structural-Behavioral Correlates Underlying Grooved Pegboard Test Performance Across Lifespan. / 07.07.2020 / PubMed / Full text
  • Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults. / 2019 / PubMed / Full text

GRIK2

  • Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2. / 11-12.2020 / PubMed / Full text
  • Isoforms of Ionotropic Glutamate Receptor GRIK2 Induce Senescence of Carcinoma Cells. / 01-02.2019 / PubMed / Full text

GRK5

  • Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone. / 01.05.2019 / PubMed / Full text
  • GRK5 - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders. / 2018 / PubMed / Full text

GRSF1

GSTA4

  • Impaired enzymatic reactive aldehyde-detoxifying capacity and glutathione peroxidase activity in the aged human arterial tissue. / 02.2019 / PubMed / Full text
  • Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

HAL

  • Comparison of haloperidol, non-haloperidol antipsychotics, and no pharmacotherapy for the management of delirium in an inpatient geriatric palliative care population. / 06-09.2018 / PubMed / Full text
  • Acute and long-term effects of haloperidol on surgery-induced neuroinflammation and cognitive deficits in aged rats. / 06.2019 / PubMed / Full text

HAPLN1

  • Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility. / 01.2019 / PubMed / Full text
  • Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis. / 01.2019 / PubMed / Full text

HAS1

  • A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text
  • Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. / 01.2018 / PubMed / Full text

HBP1

  • Suppression of p38/HBP1 pathway alleviates hyperosmotic stress-induced senescent progression of chondrocyte senescence. / 03-04.2020 / PubMed / Full text
  • Transcription factor HBP1: A regulator of senescence and apoptosis of preadipocytes. / 17.09.2019 / PubMed / Full text

HCN1

  • Protein expression changes of HCN1 and HCN2 in hippocampal subregions of gerbils during the normal aging process. / 11.2019 / PubMed / Full text
  • HCN as a Mediator of Urinary Homeostasis: Age-Associated Changes in Expression and Function in Adrenergic Detrusor Relaxation. / 15.02.2019 / PubMed / Full text

HGD

  • High-glucose diets induce mitochondrial dysfunction in Caenorhabditis elegans. / 2019 / PubMed / Full text
  • A high glucose diet induces autophagy in a HLH-30/TFEB-dependent manner and impairs the normal lifespan of [i]C. elegans[/i]. / 05.10.2018 / PubMed / Full text

HLA-A

  • Reduced expression of the lncRNA NRON is a potential hallmark of the CMV-amplified CD8+ T cell accumulations commonly seen in older humans. / 01.2019 / PubMed / Full text
  • Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. / 2017 / PubMed / Full text

HLA-B

  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
  • Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. / 2017 / PubMed / Full text

HLA-C

  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text
  • Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8 T-Cell Repertoire in Older People. / 2017 / PubMed / Full text

HLA-DPB1

  • 17th IHIW component "Immunogenetics of Ageing" - New NGS data. / 09.2019 / PubMed / Full text
  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

HMOX1

  • Well-aging: A new strategy for skin homeostasis under multi-stressed conditions. / 02.2020 / PubMed / Full text
  • Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. / 08.2019 / PubMed / Full text

HRAS

  • How do combinations of unhealthy behaviors relate to attitudinal factors and subjective health among the adult population in the Netherlands? / 03.04.2020 / PubMed / Full text
  • Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype. / 07.02.2020 / PubMed / Full text

HSF2

  • Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text
  • Nutrition and water temperature regulate the expression of heat-shock proteins in golden pompano larvae (Trachinotus ovata, Limmaeus 1758). / 04.2019 / PubMed / Full text

HSPA1A

  • Vitamin D3 treatment regulates apoptosis, antioxidant defense system, and DNA integrity in the epididymal sperm of an aged rat model. / 12.2019 / PubMed / Full text
  • The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells. / 01.09.2018 / PubMed / Full text

ID1

  • Commentary on Some Recent Theses Relevant to Combating Aging: April 2019. / 04.2019 / PubMed / Full text
  • ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras. / 12.09.2017 / PubMed / Full text

ID3

  • Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text
  • Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

IDE

  • Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity. / 2020 / PubMed / Full text
  • Hyperinsulinemia is associated with increasing insulin secretion but not with decreasing insulin clearance in an age-related metabolic dysfunction mice model. / 06.2019 / PubMed / Full text

IDS

  • Effect of immediate dentine sealing on the aging and fracture strength of lithium disilicate inlays and overlays. / 10.2020 / PubMed / Full text
  • Increased double limb support times during walking in right limb dominant healthy older adults with low bone density. / 06.2018 / PubMed / Full text

IGFBP1

  • Role of IGFBP1 in the senescence of vascular endothelial cells and severity of aging‑related coronary atherosclerosis. / 11.2019 / PubMed / Full text
  • Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age. / 04.2018 / PubMed / Full text

IL1A

  • IL1B triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via CCL2. / 25.10.2020 / PubMed / Full text
  • Age-associated mRNA expression changes in bovine endometrial cells in vitro. / 14.08.2017 / PubMed / Full text

IL7

INSL3

  • Effect of Thyroxine Replacement on Leydig Cell and Sertoli Cell Function in Men with Hypothyroidism. / 05-06.2020 / PubMed / Full text
  • Age related and seasonal changes of plasma concentrations of insulin-like peptide 3 and testosterone from birth to early-puberty in Thoroughbred male horses. / 01.07.2019 / PubMed / Full text

IQGAP1

  • IQGAP1-dysfunction leads to induction of senescence in human vascular smooth muscle cells. / 09.2020 / PubMed / Full text
  • Hyaluronan-binding protein 1 (HABP1) overexpression triggers induction of senescence in fibroblasts cells. / 06.2020 / PubMed / Full text

IRF4

  • Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text
  • Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice. / 11.2017 / PubMed / Full text

IRF7

  • Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood. / 14.01.2019 / PubMed / Full text
  • Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text

KIT

  • Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-KIT. / 04.2020 / PubMed / Full text
  • miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. / 06.2018 / PubMed / Full text

L1CAM

  • Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression. / 12.09.2019 / PubMed / Full text
  • Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence. / 28.03.2018 / PubMed / Full text

LAMP2

  • A pH probe inhibits senescence in mesenchymal stem cells. / 07.12.2018 / PubMed / Full text
  • Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. / 02.2018 / PubMed / Full text

LAT2

  • Blood glucose, amino acid profiles and nutrient transporter gene expressions in the small intestine of low and normal birthweight piglets during the early suckling period. / 05.2019 / PubMed / Full text
  • Skeletal muscle: from birth to old age, routes to mechanical and metabolic failure. / 2017 / PubMed / Full text

LATS2

  • [Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. / 25.06.2019 / PubMed
  • YAP1-LATS2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis. / 03.2019 / PubMed / Full text

LCT

  • Functional MRI of Letter Cancellation Task Performance in Older Adults. / 2019 / PubMed / Full text
  • Milk Intake at Midlife and Cognitive Decline over 20 Years. The Atherosclerosis Risk in Communities (ARIC) Study. / 17.10.2017 / PubMed / Full text

LDHA

  • Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16 inactivation. / 26.02.2018 / PubMed / Full text
  • Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming. / 05.2018 / PubMed / Full text

LIF

  • Aminopeptidase N expression in the endometrium could affect endometrial receptivity. / 25.06.2019 / PubMed / Full text
  • Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. / 15.03.2019 / PubMed / Full text

LONP1

  • Mitochondria organize the cellular proteostatic response and promote cellular senescence. / 15.03.2019 / PubMed / Full text
  • A mitochondrial FUNDC1/HSC70 interaction organizes the proteostatic stress response at the risk of cell morbidity. / 01.02.2019 / PubMed / Full text

LOXL2

  • Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice. / 27.09.2019 / PubMed / Full text
  • Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening. / 01.07.2019 / PubMed / Full text

LRP4

  • Multiple MuSK signaling pathways and the aging neuromuscular junction. / 13.07.2020 / PubMed / Full text
  • Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4. / 10.10.2018 / PubMed / Full text

LRP5

  • LRP5 in age-related changes in vascular and alveolar morphogenesis in the lung. / 05.01.2019 / PubMed / Full text
  • Wnt1 is an Lrp5-independent bone-anabolic Wnt ligand. / 07.11.2018 / PubMed / Full text

LSR

  • Age-related changes in regiospecific expression of Lipolysis Stimulated Receptor (LSR) in mice brain. / 2019 / PubMed / Full text
  • Discriminating Alzheimer's disease progression using a new hippocampal marker from T1-weighted MRI: The local surface roughness. / 01.04.2019 / PubMed / Full text

LTB

  • Aging and Hyperglycemia Intensify Dyslipidemia-Induced Oxidative Stress and Inflammation in Rats: Assessment of Restorative Potentials of ALA and EPA + DHA. / 06.2019 / PubMed / Full text
  • Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis. / 11.2017 / PubMed / Full text

MALT1

  • MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. / 29.04.2020 / PubMed / Full text
  • MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging. / 2019 / PubMed / Full text

MAP1LC3B

  • The effect of aging on the autophagic and heat shock response in human peripheral blood mononuclear cells. / 01.09.2018 / PubMed / Full text
  • Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text

MAPK14

  • Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. / 10.2018 / PubMed / Full text
  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text

MAPK3

  • A tyrosine kinase-activating variant Asn666Ser in PDGFRB causes a progeria-like condition in the severe end of Penttinen syndrome. / 04.2019 / PubMed / Full text
  • Micro-RNAS Regulate Metabolic Syndrome-induced Senescence in Porcine Adipose Tissue-derived Mesenchymal Stem Cells through the P16/MAPK Pathway. / 10.2018 / PubMed / Full text

MAPKAPK2

  • Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. / 03.12.2019 / PubMed / Full text
  • Cell fate regulation by reticulon-4 in human prostate cancers. / 07.2019 / PubMed / Full text

MARCO

  • Age-dependent effect between MARCO and TLR4 on PMMA particle phagocytosis by macrophages. / 08.2019 / PubMed / Full text
  • Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria. / 01.11.2017 / PubMed / Full text

MCL1

  • MCL1 gene silencing promotes senescence and apoptosis of glioma cells via inhibition of the PI3K/Akt signaling pathway. / 01.2019 / PubMed / Full text
  • A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress. / 10.08.2017 / PubMed / Full text

MCM2

  • Trophoblast type-specific expression of senescence markers in the human placenta. / 15.09.2019 / PubMed / Full text
  • Changes in MCM2-7 proteins at senescence. / 27.07.2019 / PubMed / Full text

MCM7

  • Changes in MCM2-7 proteins at senescence. / 27.07.2019 / PubMed / Full text
  • Inhibition of CIP2A attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma. / 08.01.2018 / PubMed / Full text

MDH1

  • Oxidative Damage to the TCA Cycle Enzyme MDH1 Dysregulates Bioenergetic Enzymatic Activity in the Aged Murine Brain. / 03.04.2020 / PubMed / Full text
  • Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro. / 08.2019 / PubMed / Full text

MEIS1

  • Down-regulation of MEIS1 promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes. / 06.2019 / PubMed / Full text
  • Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

MIF

  • Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice. / 09.2019 / PubMed / Full text
  • Macrophage migration inhibitory factor knockdown inhibit viability and induce apoptosis of PVM/Ms. / 12.2017 / PubMed / Full text

MLH1

  • The somatic mutation landscape of the human body. / 24.12.2019 / PubMed / Full text
  • RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text

MMP3

  • Systemic analysis of gene expression profiles in porcine granulosa cells during aging. / 14.11.2017 / PubMed / Full text
  • Identification of a pyridine derivative inducing senescence in ovarian cancer cell lines via P21 activation. / 05.2018 / PubMed / Full text

MTM1

  • Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice. / 20.03.2019 / PubMed / Full text
  • Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy. / 19.11.2018 / PubMed / Full text

MTMR14

  • EDTP/MTMR14: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates. / 13.07.2019 / PubMed / Full text
  • Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster. / 16.02.2019 / PubMed / Full text

MVD

  • Prostate cancer aggressiveness and age: Impact of p53, BCL-2 and microvessel density. / 12.2018 / PubMed / Full text
  • Assessing Microvascular Function in Humans from a Chronic Disease Perspective. / 12.2017 / PubMed / Full text

NAV2

  • Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text
  • Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text

NCL

  • Factors Affecting Microvascular Responses in the Bulbar Conjunctiva in Habitual Contact Lens Wearers. / 01.08.2018 / PubMed / Full text
  • Small nucleoli are a cellular hallmark of longevity. / 30.08.2017 / PubMed / Full text

NDNF

  • Effect of neuron-derived neurotrophic factor on rejuvenation of human adipose-derived stem cells for cardiac repair after myocardial infarction. / 09.2019 / PubMed / Full text
  • Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury. / 12.2017 / PubMed / Full text

NDUFB8

  • Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. / 23.05.2018 / PubMed / Full text
  • Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions. / 06.2018 / PubMed / Full text

NECTIN2

  • Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text
  • Apolipoprotein E region molecular signatures of Alzheimer's disease. / 08.2018 / PubMed / Full text

NLRC4

  • Hyperglycemia-induced inflamm-aging accelerates gingival senescence via NLRC4 phosphorylation. / 06.12.2019 / PubMed / Full text
  • Contribution of the inflammasome to inflammaging. / 2018 / PubMed / Full text

NMNAT1

  • ADNP differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. / 06.2019 / PubMed / Full text
  • Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

NMNAT2

  • NMNAT2-mediated NAD generation is essential for quality control of aged oocytes. / 06.2019 / PubMed / Full text
  • Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy. / 03.10.2017 / PubMed / Full text

NNMT

  • Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle. / 05.2019 / PubMed / Full text
  • Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy. / 09.2018 / PubMed / Full text

NOP10

  • Pseudouridylation defect due to [i]DKC1[/i] and [i]NOP10[/i] mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. / 30.06.2020 / PubMed / Full text
  • Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. / 04.2018 / PubMed / Full text

NOS2

  • Genetic background, epigenetic factors and dietary interventions which influence human longevity. / 10.2019 / PubMed / Full text
  • Secreted α-Klotho maintains cartilage tissue homeostasis by repressing [i]NOS2[/i] and [i]ZIP8-MMP13[/i] catabolic axis. / 19.06.2018 / PubMed / Full text

NOTCH3

  • Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text
  • Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

NPR1

  • The NPR1-WRKY46-WRKY6 signaling cascade mediates probenazole/salicylic acid-elicited leaf senescence in Arabidopsis thaliana. / 03.12.2020 / PubMed / Full text
  • Loss of proton/calcium exchange 1 results in the activation of plant defense and accelerated senescence in Arabidopsis. / 07.2020 / PubMed / Full text

NRK

  • [Molecular mechanisms of mycelium of Cordyceps sinensis ameliorating renal tubular epithelial cells aging induced by D-galactose via inhibiting autophagy-related AMPK/ULK1 signaling activation]. / 03.2019 / PubMed / Full text
  • Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy. / 24.12.2018 / PubMed / Full text

NTS

  • Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension. / 08.2019 / PubMed / Full text
  • Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. / 01.08.2018 / PubMed / Full text

OAT

  • Opioid agonist treatment reduces losses in quality of life and quality-adjusted life expectancy in heroin users: Evidence from real world data. / 01.08.2019 / PubMed / Full text
  • Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats. / 02.2019 / PubMed / Full text

PAK1

  • 1,2,3-Triazolyl ester of ketorolac (15K): Boosting both heat-endurance and lifespan of C. elegans by down-regulating PAK1 at nM levels. / 2018 / PubMed / Full text
  • From bench (laboratory) to bed (hospital/home): How to explore effective natural and synthetic PAK1-blockers/longevity-promoters for cancer therapy. / 15.12.2017 / PubMed / Full text

PAPPA

  • Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text
  • Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

PDC

  • The mitochondrial translocase of the inner membrane PaTim54 is involved in defense response and longevity in Podospora anserina. / 11.2019 / PubMed / Full text
  • Neuron-specific knockdown of Drosophila PDHB induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting. / 15.05.2018 / PubMed / Full text

PDCD4

  • Petal abscission in roses is associated with the activation of a truncated version of the animal PDCD4 homologue, RbPCD1. / 11.2019 / PubMed / Full text
  • PDCD4 Knockdown Induces Senescence in Hepatoma Cells by Up-Regulating the p21 Expression. / 2018 / PubMed / Full text

PDE4D

  • Phosphodiesterase PDE4D Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau. / 2020 / PubMed / Full text
  • Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function. / 02.12.2018 / PubMed / Full text

PER1

  • Quercetin, caffeic acid and resveratrol regulate circadian clock genes and aging-related genes in young and old human lung fibroblast cells. / 02.2020 / PubMed / Full text
  • Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text

PF4

  • TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity. / 07.2019 / PubMed / Full text
  • Effects of collagen peptides intake on skin ageing and platelet release in chronologically aged mice revealed by cytokine array analysis. / 01.2018 / PubMed / Full text

PGD

  • Primary Care for the Elderly Bereaved: Recommendations for Medical Education. / 12.2018 / PubMed / Full text
  • High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles. / 01.03.2018 / PubMed / Full text

PGP

  • Age-associated changes of the intrinsic nervous system in relation with interstitial cells in the pre-weaning goat rumen. / 14.07.2019 / PubMed / Full text
  • Changes in the interstitial cells of Cajal and neuronal nitric oxide synthase positive neuronal cells with aging in the esophagus of F344 rats. / 2017 / PubMed / Full text

PIEZO1

  • Niche stiffness underlies the ageing of central nervous system progenitor cells. / 09.2019 / PubMed / Full text
  • On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, PIEZO1, and Gardos Channels. / 2017 / PubMed / Full text

PIK3CG

  • Myocyte enhancer factor 2A delays vascular endothelial cell senescence by activating the PI3K/p-Akt/SIRT1 pathway. / 10.06.2019 / PubMed / Full text
  • MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells. / 18.03.2019 / PubMed / Full text

PLD2

  • Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. / 08.2019 / PubMed / Full text
  • Role of phospholipase D in the lifespan of Caenorhabditis elegans. / 06.04.2018 / PubMed / Full text

PLIN2

  • Cardiac overexpression of perilipin 2 induces atrial steatosis, connexin 43 remodeling, and atrial fibrillation in aged mice. / 01.12.2019 / PubMed / Full text
  • HDAC6 Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of PLIN2 in Drosophila. / 09.10.2017 / PubMed / Full text

PLK4

  • A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence. / 05.2020 / PubMed / Full text
  • Differential expression of AURKA/PLK4 in quiescence and senescence of osteosarcoma U2OS cells. / 04.2020 / PubMed / Full text

POSTN

  • A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals POSTN As a New Element in Proline Metabolic Disorder. / 12.2018 / PubMed / Full text
  • Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

POT1

  • MiR-185 targets POT1 to induce telomere dysfunction and cellular senescence. / 18.07.2020 / PubMed / Full text
  • Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence. / 2019 / PubMed / Full text

PPID

  • Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population. / 03.2020 / PubMed / Full text
  • Epidemiology of pituitary pars intermedia dysfunction: A systematic literature review of clinical presentation, disease prevalence and risk factors. / 05.2018 / PubMed / Full text

PPM1D

  • Detectible mosaic truncating PPM1D mutations, age and breast cancer risk. / 06.2019 / PubMed / Full text
  • Age-related remodelling of oesophageal epithelia by mutated cancer drivers. / 01.2019 / PubMed / Full text

PRC1

  • Timosaponin A-III inhibits oncogenic phenotype via regulation of PcG protein BMI1 in breast cancer cells. / 07.2018 / PubMed / Full text
  • Epigenetic factors Polycomb (Pc) and Suppressor of zeste (Su(z)2) negatively regulate longevity in Drosophila melanogaster. / 02.2018 / PubMed / Full text

PROC

  • Does midlife aging impact women's sleep duration, continuity, and timing?: A longitudinal analysis from the Study of Women's Health Across the Nation. / 15.04.2020 / PubMed / Full text
  • Effects of feeding frequency of an elevated plane of milk replacer and calf age on behavior, and glucose and insulin kinetics in male Holstein calves. / 07.2019 / PubMed / Full text

PSEN2

  • Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2. / 2020 / PubMed / Full text
  • Loss of presenilin 2 age-dependently alters susceptibility to acute seizures and kindling acquisition. / 03.2020 / PubMed / Full text

PTBP1

  • Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. / 11.12.2018 / PubMed / Full text
  • PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. / 09.07.2018 / PubMed / Full text

PTPN11

  • Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array. / 01.10.2020 / PubMed / Full text
  • A tyrosine kinase-activating variant Asn666Ser in PDGFRB causes a progeria-like condition in the severe end of Penttinen syndrome. / 04.2019 / PubMed / Full text

PTS

  • Posttraumatic stress symptom persistence across 24 years: association with brain structures. / 08.2020 / PubMed / Full text
  • Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis. / 18.07.2018 / PubMed / Full text

PTX3

  • Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. / 27.01.2020 / PubMed / Full text
  • Sex Differences in the Association Between Pentraxin 3 and Cognitive Decline: The Cardiovascular Health Study. / 13.07.2020 / PubMed / Full text

PUM2

  • PUMILIO hyperactivity drives premature aging of [i]Norad[/i]-deficient mice. / 08.02.2019 / PubMed / Full text
  • The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging. / 21.02.2019 / PubMed / Full text

PYY

  • Peptide YY (PYY) Is Expressed in Human Skeletal Muscle Tissue and Expanding Human Muscle Progenitor Cells. / 2019 / PubMed / Full text
  • Peptide YY induces characteristic meal patterns of aged mice. / 11.2017 / PubMed / Full text

RAD52

  • Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae. / 01.08.2019 / PubMed / Full text
  • Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human RAD52 gene in a cardiovascular cohort. / 10.2017 / PubMed / Full text

RAG1

  • T cell senescence accelerates Angiotensin II-induced target organ damage. / 12.02.2020 / PubMed / Full text
  • Aged murine hematopoietic stem cells drive aging-associated immune remodeling. / 09.08.2018 / PubMed / Full text

RAN

  • Rapid automatized naming (RAN): effects of aging on a predictor of reading skill. / 17.08.2020 / PubMed / Full text
  • SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F. / 01.10.2018 / PubMed / Full text

RGN

  • Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04. / 2018 / PubMed / Full text
  • Effect of supplementation of recombinant Regucalcin in extender on cryopreservation of spermatozoa of water buffalo (Bubalus bubalis). / 11.2017 / PubMed / Full text

RIG

  • Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling. / 2017 / PubMed / Full text
  • Aging impairs both primary and secondary RIG-I signaling for interferon induction in human monocytes. / 12.12.2017 / PubMed / Full text

RNF8

  • Expression of RNF8 on cochlear apoptosis and aging in mice of different ages. / 03-Apr,.2019 / PubMed
  • Function of RAD6B and RNF8 in spermatogenesis. / 2018 / PubMed / Full text

RPS6

  • Regulation of Amino Acid Transporters and Sensors in Response to a High protein Diet: A Randomized Controlled Trial in Elderly Men. / 2019 / PubMed / Full text
  • Endothelial replicative senescence delayed by the inhibition of MTORC1 signaling involves MicroRNA-107. / 08.2018 / PubMed / Full text

RTEL1

  • Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants. / 12.2019 / PubMed / Full text
  • Genome-wide association study of telomere length among South Asians identifies a second RTEL1 association signal. / 01.2018 / PubMed / Full text

RUNX1

  • RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins. / 03.2018 / PubMed / Full text
  • Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text

S100A4

  • Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette smoke-induced mitochondrial dysfunction in mice. / 15.12.2019 / PubMed / Full text
  • Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. / 2018 / PubMed / Full text

S1PR1

  • Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair. / 22.06.2020 / PubMed / Full text
  • Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota. / 04.01.2018 / PubMed / Full text

SAA1

  • Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells. / 2018 / PubMed / Full text
  • Association between local inflammation and breast tissue age-related lobular involution among premenopausal and postmenopausal breast cancer patients. / 2017 / PubMed / Full text

SCAP

  • Dementia outcomes after addition of proxy-based assessments for deceased or proxy-dependent participants. / 10.2019 / PubMed / Full text
  • Increased hepatic INSIG-SCAP-SREBP expression is associated with cholesterol metabolism disorder in assisted reproductive technology-conceived aged mice. / 03.2019 / PubMed / Full text

SESN2

  • Copy Number Alterations in Papillary Thyroid Carcinomas: Does Loss of [i]SESN2[/i] Have a Role in Age-related Different Prognoses? / 09-10.2020 / PubMed / Full text
  • Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea. / 11.10.2017 / PubMed / Full text

SLC25A24

  • De Novo Mutations in SLC25A24 Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise. / 02.11.2017 / PubMed / Full text
  • De Novo Mutations in SLC25A24 Cause a Craniosynostosis Syndrome with Hypertrichosis, Progeroid Appearance, and Mitochondrial Dysfunction. / 02.11.2017 / PubMed / Full text

SMAD2

  • Prostate epithelial-specific expression of activated PI3K drives stromal collagen production and accumulation. / 02.2020 / PubMed / Full text
  • Restoring extracellular matrix synthesis in senescent stem cells. / 10.2019 / PubMed / Full text

SMAD4

  • A clinical trial of somatic and germline analyses for healthy longevity in a postoperative cancer patient. / 09.2019 / PubMed / Full text
  • E47 Governs the MYC-CDKN1B/p27 -RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type p53. / 2018 / PubMed / Full text

SNCB

  • Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. / 08.2019 / PubMed / Full text
  • Age-related Beta-synuclein Alters the p53/Mdm2 Pathway and Induces the Apoptosis of Brain Microvascular Endothelial Cells In Vitro. / 05.2018 / PubMed / Full text

SOCS1

  • Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus. / 06.2019 / PubMed / Full text
  • SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes. / 28.10.2017 / PubMed / Full text

SORL1

  • A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study. / 05.2019 / PubMed / Full text
  • Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age. / 2018 / PubMed / Full text

SOST

  • Low Serum Levels of DKK2 Predict Incident Low-Impact Fracture in Older Women. / 07.2019 / PubMed / Full text
  • Bone adaptation in response to treadmill exercise in young and adult mice. / 06.2018 / PubMed / Full text

SPARCL1

  • Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment. / 18.06.2019 / PubMed / Full text
  • SPARCL1 Accelerates Symptom Onset in Alzheimer's Disease and Influences Brain Structure and Function During Aging. / 2018 / PubMed / Full text

SPR

  • Regulation of lifespan by neural excitation and REST. / 10.2019 / PubMed / Full text
  • How many geriatricians should, at minimum, be staffing health regions in Australia? / 03.2018 / PubMed / Full text

SRR

  • Mediterranean diet and its components in relation to all-cause mortality: meta-analysis. / 11.2018 / PubMed / Full text
  • Genetic Biomarkers on Age-Related Cognitive Decline. / 2017 / PubMed / Full text

SSB

  • Modelling the Effects of Beverage Substitution during Adolescence on Later Obesity Outcomes in Early Adulthood: Results from the Raine Study. / 03.12.2019 / PubMed / Full text
  • WHIRLY1 Occupancy Affects Histone Lysine Modification and [i]WRKY53[/i] Transcription in [i]Arabidopsis[/i] Developmental Manner. / 2018 / PubMed / Full text

STAT5A

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text
  • SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes. / 28.10.2017 / PubMed / Full text

STIM1

  • Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis. / 02.2020 / PubMed / Full text
  • Ca entry via TRPC1 is essential for cellular differentiation and modulates secretion via the SNARE complex. / 01.07.2019 / PubMed / Full text

SUV39H1

  • Increase in hippocampal histone H3K9me3 is negatively correlated with memory in old male mice. / 04.2020 / PubMed / Full text
  • Triptolide Promotes Senescence of Prostate Cancer Cells Through Histone Methylation and Heterochromatin Formation / 27.09.2017 / PubMed / Full text

SV2A

  • Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging. / 01.10.2018 / PubMed / Full text
  • Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. / 10.2018 / PubMed / Full text

TAS2R16

  • Taste receptor polymorphisms and longevity: a systematic review and meta-analysis. / 10.11.2020 / PubMed / Full text
  • Taste receptors, innate immunity and longevity: the case of TAS2R16 gene. / 2019 / PubMed / Full text

TAS2R38

  • TAS2R38 bitter taste receptor and attainment of exceptional longevity. / 02.12.2019 / PubMed / Full text
  • Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. / 18.10.2018 / PubMed / Full text

TAT

  • Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides. / 2019 / PubMed / Full text
  • Effects of HIV-1 gp120 and TAT-derived microvesicles on endothelial cell function. / 01.05.2019 / PubMed / Full text

TBC1D5

  • TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry. / 09.06.2020 / PubMed / Full text
  • Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling. / 02.09.2019 / PubMed / Full text

TBK1

  • Parkin overexpression alleviates cardiac aging through facilitating K63-polyubiquitination of TBK1 to facilitate mitophagy. / 01.01.2021 / PubMed / Full text
  • TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. / 06.09.2018 / PubMed / Full text

TCF7L2

  • A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder. / 03.2020 / PubMed / Full text
  • Lifelong physical activity is associated with promoter hypomethylation of genes involved in metabolism, myogenesis, contractile properties and oxidative stress resistance in aged human skeletal muscle. / 01.03.2019 / PubMed / Full text

TIMELESS

  • Loss of circadian protein TIMELESS accelerates the progression of cellular senescence. / 18.09.2018 / PubMed / Full text
  • Clock gene expression and locomotor activity predict death in the last days of life in Drosophila melanogaster. / 09.08.2018 / PubMed / Full text

TIMP1

  • Design, cyclization, and optimization of MMP13-TIMP1 interaction-derived self-inhibitory peptides against chondrocyte senescence in osteoarthritis. / 01.2019 / PubMed / Full text
  • Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9. / 2018 / PubMed / Full text

TLR7

  • Bovine Lactoferrin Enhances TLR7-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D. / 2018 / PubMed / Full text
  • B cell responses to apoptotic cells in MFG-E8-/- mice. / 2018 / PubMed / Full text

TMPRSS2

  • Susceptibility to COVID-19 in populations with health disparities: Posited involvement of mitochondrial disorder, socioeconomic stress, and pollutants. / 09.09.2020 / PubMed / Full text
  • Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age. / 03.06.2020 / PubMed / Full text

TNNT3

  • Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. / 06.02.2019 / PubMed / Full text
  • Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs. / 15.07.2018 / PubMed / Full text

TPO

  • Megakaryocytes promote osteoclastogenesis in aging. / 07.07.2020 / PubMed / Full text
  • To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex-independent) NOD.H2 mice. / 04.2019 / PubMed / Full text

TREX1

  • Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. / 2019 / PubMed / Full text
  • Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

TRH

  • Neonatal exposure to bisphenol A alters the hypothalamic-pituitary-thyroid axis in female rats. / 15.03.2018 / PubMed / Full text
  • Effect of dietary carbohydrates and time of year on ACTH and cortisol concentrations in adult and aged horses. / 04.2018 / PubMed / Full text

TRPC6

  • Redox and mTOR-dependent regulation of plasma lamellar calcium influx controls the senescence-associated secretory phenotype. / 11.2020 / PubMed / Full text
  • TRPC6 in simulated microgravity of intervertebral disc cells. / 10.2018 / PubMed / Full text

TRPM7

  • mRNA expression of transient receptor potential melastatin (TRPM) channels 2 and 7 in perinatal brain development. / 10.2018 / PubMed / Full text
  • Role of kinase-coupled TRP channels in mineral homeostasis. / 04.2018 / PubMed / Full text

TRPM8

  • Morphological and functional changes in TRPM8-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice. / 01.08.2018 / PubMed / Full text
  • A comparative study on the therapeutic effect of TRPV1, TRPA1, and TRPM8 agonists on swallowing dysfunction associated with aging and neurological diseases. / 02.2018 / PubMed / Full text

TTN

  • LncRNA TTN-AS1 regulates osteosarcoma cell apoptosis and drug resistance via the miR-134-5p/MBTD1 axis. / 10.10.2019 / PubMed / Full text
  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

TXNRD2

  • Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression. / 10.2020 / PubMed / Full text
  • Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice. / 22.03.2018 / PubMed / Full text

VCAM1

  • Sunitinib facilitates metastatic breast cancer spreading by inducing endothelial cell senescence. / 29.09.2020 / PubMed / Full text
  • Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1. / 06.2019 / PubMed / Full text

VCAN

  • Deletion of miR-126a Promotes Hepatic Aging and Inflammation in a Mouse Model of Cholestasis. / 07.06.2019 / PubMed / Full text
  • Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells. / 2019 / PubMed / Full text

WFS1

  • Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila. / 01.2018 / PubMed / Full text
  • A nonsynonymous mutation in the WFS1 gene in a Finnish family with age-related hearing impairment. / 11.2017 / PubMed / Full text

WIPI2

  • Neuronal autophagy declines substantially with age and is rescued by overexpression of WIPI2. / 02.2020 / PubMed / Full text
  • The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. / 04.2019 / PubMed / Full text

XRCC1

  • [Protective effect of Wuzi Yanzong recipe on testicular DNA oxidative damage in natural ageing rats]. / 07.2018 / PubMed / Full text
  • The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity. / 2018 / PubMed / Full text

YAP1

  • [Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. / 25.06.2019 / PubMed
  • YAP1-LATS2 feedback loop dictates senescent or malignant cell fate to maintain tissue homeostasis. / 03.2019 / PubMed / Full text

ZC3H12A

  • Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation. / 12.2019 / PubMed / Full text
  • Prediction and characterization of human ageing-related proteins by using machine learning. / 06.03.2018 / PubMed / Full text

ZEB1

  • MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1. / 12.2018 / PubMed / Full text
  • Ultraviolet A irradiation induces senescence in human dermal fibroblasts by down-regulating DNMT1 via ZEB1. / 16.02.2018 / PubMed / Full text

ZEB2

  • miR-200b regulates cellular senescence and inflammatory responses by targeting ZEB2 in pulmonary emphysema. / 12.2020 / PubMed / Full text
  • MicroRNA-145 induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by ZEB2. / 05.2019 / PubMed / Full text

ZSCAN10

  • RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells. / 10.10.2017 / PubMed / Full text
  • ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors. / 09.2017 / PubMed / Full text

AACS

  • Sex differences in subjective age-associated changes in sleep: a prospective elderly cohort study. / 07.11.2020 / PubMed / Full text

AANAT

  • Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis. / 01.06.2019 / PubMed / Full text

ABCC9

  • TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels. / 05.2019 / PubMed / Full text

ABCE1

  • Widespread Accumulation of Ribosome-Associated Isolated 3' UTRs in Neuronal Cell Populations of the Aging Brain. / 27.11.2018 / PubMed / Full text

ABCG1

  • Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. / 08.2018 / PubMed / Full text

ABCG5

  • 2, 3, 4', 5-tetrahydroxystilbene-2-0-β-d Glycoside Attenuates Age- and Diet-Associated Non-Alcoholic Steatohepatitis and Atherosclerosis in LDL Receptor Knockout Mice and Its Possible Mechanisms. / 01.04.2019 / PubMed / Full text

ABHD12

  • Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype. / 2019 / PubMed / Full text

ABI3BP

  • Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing ABI3BP in gallbladder cancer cells. / 07.06.2019 / PubMed / Full text

ABL1

  • European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia. / 04.2020 / PubMed / Full text

ABLIM3

  • Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization. / 05.2018 / PubMed / Full text

ACAD10

  • Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

ACAD9

  • Identification of a novel mitochondrial complex I assembly factor ACDH-12 in Caenorhabditis elegans. / 05.2019 / PubMed / Full text

ACADM

  • High fat diet aggravates atrial and ventricular remodeling of hypertensive heart disease in aging rats. / 07.2018 / PubMed / Full text

ACAN

  • MicroRNA-143-5p targeting eEF2 gene mediates intervertebral disc degeneration through the AMPK signaling pathway. / 15.04.2019 / PubMed / Full text

ACAT2

  • Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. / 15.12.2017 / PubMed / Full text

ACD

  • Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging. / 02.12.2019 / PubMed / Full text

ACMSD

  • De novo NAD synthesis enhances mitochondrial function and improves health. / 11.2018 / PubMed / Full text

ACO1

  • Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine. / 24.04.2019 / PubMed / Full text

ACSL5

  • Ageing sensitized by iPLA β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids. / 12.2017 / PubMed / Full text

ACTA2

  • Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. / 2018 / PubMed / Full text

ACTR3B

  • Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text

ACVR1

  • Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome. / 2019 / PubMed / Full text

ADAMTS3

  • Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text

ADAMTS9

  • Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

ADAR

  • Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. / 09.2018 / PubMed / Full text

ADCK1

  • Functional analysis of Aarf domain-containing kinase 1 in Drosophila melanogaster. / 09.2019 / PubMed / Full text

ADD2

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

ADH1B

  • Telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde. / 02.2019 / PubMed / Full text

ADIPOR1

  • A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. / 2018 / PubMed / Full text

ADK

  • Deletion of pancreatic β-cell adenosine kinase improves glucose homeostasis in young mice and ameliorates streptozotocin-induced hyperglycaemia. / 07.2019 / PubMed / Full text

ADNP

  • ADNP differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. / 06.2019 / PubMed / Full text

ADNP2

  • ADNP differentially interact with genes/proteins in correlation with aging: a novel marker for muscle aging. / 06.2019 / PubMed / Full text

ADORA2B

  • Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss. / 12.2020 / PubMed / Full text

ADRA2A

  • α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway. / 2020 / PubMed / Full text

ADRA2B

  • Aging and the Combined effects of ADRA2B and CB1 deletions on Affective Working Memory. / 11.03.2019 / PubMed / Full text

ADRM1

  • Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. / 01.08.2018 / PubMed / Full text

AGAP2

  • Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2. / 05.08.2019 / PubMed / Full text

AHCY

  • Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text

AIDA

  • Identification of Postharvest Senescence Regulators Through Map-Based Cloning Using Detached Arabidopsis Inflorescences as a Model Tissue. / 2018 / PubMed / Full text

AIF1

  • Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text

AKAP12

  • A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter. / 05.2018 / PubMed / Full text

AKAP17A

  • The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. / 10.2019 / PubMed / Full text

AKT2

  • Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

AKT3

  • Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma. / 10.2018 / PubMed / Full text

AKTIP

  • Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits. / 08.2018 / PubMed / Full text

ALAS1

  • Heterozygous disruption of ALAS1 in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver. / 08.12.2020 / PubMed / Full text

ALDH3A1

  • Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs). / 13.02.2019 / PubMed / Full text

ALDOA

  • An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. / 06.2019 / PubMed / Full text

ALK

  • Catalog of Lung Cancer Gene Mutations Among Chinese Patients. / 2020 / PubMed / Full text

ALKBH1

  • ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed

ALKBH2

  • ALKB-8, a 2-Oxoglutarate-Dependent Dioxygenase and S-Adenosine Methionine-Dependent Methyltransferase Modulates Metabolic Events Linked to Lysosome-Related Organelles and Aging in C. elegans. / 2018 / PubMed

ALOX12

  • Arachidonate 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid contribute to stromal aging-induced progression of pancreatic cancer. / 15.05.2020 / PubMed / Full text

ALOX5

  • Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme. / 01.01.2020 / PubMed / Full text

AMFR

  • Mice heterozygous for the Cdh23/Ahl1 mutation show age-related deficits in auditory temporal processing. / 09.2019 / PubMed / Full text

AMHR2

  • Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. / 03.2018 / PubMed / Full text

AMPH

  • Effects of amphetamine exposure during adolescence on behavior and prelimbic cortex neuron activity in adulthood. / 01.09.2018 / PubMed / Full text

ANG

  • Age-related differences in the cutaneous vascular response to exogenous angiotensin II. / 01.03.2019 / PubMed / Full text

ANGPT2

  • Systemic analysis of gene expression profiles in porcine granulosa cells during aging. / 14.11.2017 / PubMed / Full text

ANGPTL4

  • Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. / 05.2019 / PubMed / Full text

ANK2

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

ANK3

  • Age-related atrophy of cortical thickness and genetic effect of ANK3 gene in first episode MDD patients. / 26.08.2020 / PubMed / Full text

ANKS1B

  • Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text

ANPEP

  • Aminopeptidase N expression in the endometrium could affect endometrial receptivity. / 25.06.2019 / PubMed / Full text

ANXA1

  • Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging. / 26.10.2018 / PubMed / Full text

AOX1

  • N1-Methylnicotinamide: An Anti-Ovarian Aging Hormetin? / 09.2020 / PubMed / Full text

AP2B1

  • Circular RNA NF1-419 enhances autophagy to ameliorate senile dementia by binding Dynamin-1 and Adaptor protein 2 B1 in AD-like mice. / 20.12.2019 / PubMed / Full text

APLNR

  • Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects. / 13.09.2017 / PubMed / Full text

APLP2

  • Analysis of Motor Function in Amyloid Precursor-Like Protein 2 Knockout Mice: The Effects of Ageing and Sex. / 06.2019 / PubMed / Full text

APOA1

  • Effects of iron on the aggregation propensity of the N-terminal fibrillogenic polypeptide of human apolipoprotein A-I. / 08.2018 / PubMed / Full text

APOBEC1

  • Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology. / 12.12.2017 / PubMed / Full text

APOC1

  • Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text

APOC3

  • Positional Obstructive Sleep Apnea Syndrome in Elderly Patients. / 10.02.2020 / PubMed / Full text

APPL1

  • Insulin and adipokine signaling and their cross-regulation in postmortem human brain. / 12.2019 / PubMed / Full text

AQP2

  • A bell-shaped pattern of urinary aquaporin-2-bearing extracellular vesicle release in an experimental model of nephronophthisis. / 05.2019 / PubMed / Full text

AQP4

  • Overexpression of Slit2 improves function of the paravascular pathway in the aging mouse brain. / 10.2018 / PubMed / Full text

AQP5

  • Submandibular gland-specific inflammaging-induced hyposalivation in the male senescence-accelerated mouse prone -1 line (SAM-P1). / 08.2019 / PubMed / Full text

ARHGAP18

  • Stress-Induced Premature Senescence Promotes Proliferation by Activating the [i]SENEX[/i] and p16 /Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell Lymphoma / 18.11.2019 / PubMed / Full text

ARID1B

  • A 69-year-old woman with Coffin-Siris syndrome. / 08.2018 / PubMed / Full text

ARID5A

  • Differentially regulated gene expression in quiescence versus senescence and identification of ARID5A as a quiescence associated marker. / 05.2018 / PubMed / Full text

ARL13B

  • ARL13B, a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments. / 20.02.2019 / PubMed / Full text

ARNTL

  • Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text

ARNTL2

  • Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text

ARRB2

  • Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity. / 12.2019 / PubMed / Full text

ARSA

  • Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

ASB3

  • Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype. / 02.2019 / PubMed / Full text

ASB7

  • ASB7 Is a Novel Regulator of Cytoskeletal Organization During Oocyte Maturation. / 2020 / PubMed / Full text

ASIP

  • Efficacy of an agonist of α-MSH, the palmitoyl tetrapeptide-20, in hair pigmentation. / 10.2018 / PubMed / Full text

ASMT

  • The influence of ageing on the extrapineal melatonin synthetic pathway. / 09.2018 / PubMed / Full text

ASPA

  • Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. / 04.2018 / PubMed / Full text

ATF2

  • Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium. / 01.04.2018 / PubMed / Full text

ATF3

  • ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. / 04.2018 / PubMed / Full text

ATF7

  • Stress-induced and ATF7-dependent epigenetic change influences cellular senescence. / 09.2019 / PubMed / Full text

ATG10

  • Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

ATG16L1

  • The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. / 04.2019 / PubMed / Full text

ATG4B

  • Impaired autophagic activity and ATG4B deficiency are associated with increased endoplasmic reticulum stress-induced lung injury. / 27.08.2018 / PubMed / Full text

ATG4D

  • Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats. / 17.07.2019 / PubMed / Full text

ATP1A2

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

ATP2B1

  • Reduced expression of PMCA1 is associated with increased blood pressure with age which is preceded by remodelling of resistance arteries. / 10.2017 / PubMed / Full text

ATP6V0C

  • A pH probe inhibits senescence in mesenchymal stem cells. / 07.12.2018 / PubMed / Full text

ATP6V1E1

  • Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text

ATXN1

  • Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text

ATXN3

  • Rescue of ATXN3 neuronal toxicity in [i]Caenorhabditis[/i][i]elegans[/i] by chemical modification of endoplasmic reticulum stress. / 19.12.2017 / PubMed / Full text

AXL

  • Extracellular acidosis triggers a senescence-like phenotype in human melanoma cells. / 01.2020 / PubMed / Full text

BACH2

  • Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients. / 17.01.2019 / PubMed / Full text

BAG3

  • Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner. / 03.2018 / PubMed / Full text

BANF1

  • An additional case of Néstor-Guillermo progeria syndrome diagnosed in early childhood. / 10.2020 / PubMed / Full text

BARD1

  • BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in [i]Caenorhabditis elegans[/i]. / 12.2018 / PubMed / Full text

BAZ1A

  • Chromatin remodeling factor BAZ1A regulates cellular senescence in both cancer and normal cells. / 15.07.2019 / PubMed / Full text

BAZ2B

  • Two conserved epigenetic regulators prevent healthy ageing. / 03.2020 / PubMed / Full text

BBS5

  • Progressive Characterization of Visual Phenotype in Bardet-Biedl Syndrome Mutant Mice. / 01.03.2019 / PubMed / Full text

BCAS1

  • Hallmarks of the cancer cell of origin: Comparisons with "energetic" cancer stem cells (e-CSCs). / 13.02.2019 / PubMed / Full text

BCL11B

  • Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells. / 05.2018 / PubMed / Full text

BCL2L1

  • SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

BCL2L11

  • miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence. / 01.2020 / PubMed / Full text

BHLHE40

  • Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1. / 07.2020 / PubMed / Full text

BMP6

  • Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology. / 06.11.2018 / PubMed / Full text

BMP7

  • Downregulation of miR-542-3p promotes osteogenic transition of vascular smooth muscle cells in the aging rat by targeting BMP7. / 11.12.2019 / PubMed / Full text

BMPR1B

  • Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes. / 12.2018 / PubMed / Full text

BMPR2

  • Centenarians Overexpress Pluripotency-Related Genes. / 16.08.2019 / PubMed / Full text

BNC1

  • Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. / 22.01.2020 / PubMed / Full text

BOC

  • Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations. / 01.05.2020 / PubMed / Full text

BRD2

  • Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice. / 2020 / PubMed / Full text

BRD3

  • Neuroprotective effects of targeting BET proteins for degradation with dBET1 in aged mice subjected to ischemic stroke. / 07.2019 / PubMed / Full text

BTC

  • Behavioral tagging and capture: long-term memory decline in middle-aged rats. / 07.2018 / PubMed / Full text

BTG1

  • Tumor cell escape from therapy-induced senescence. / 04.2019 / PubMed / Full text

C2CD2

  • Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort. / 20.11.2017 / PubMed / Full text

CA12

  • Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text

CABLES1

  • CABLES1 Deficiency Impairs Quiescence and Stress Responses of Hematopoietic Stem Cells in Intrinsic and Extrinsic Manners. / 13.08.2019 / PubMed / Full text

CACNA1B

  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

CACNA1S

  • Increased calcium channel in the lamina propria of aging rat. / 31.10.2019 / PubMed / Full text

CALR

  • Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender. / 10.2017 / PubMed / Full text

CAMSAP1

  • Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text

CAP2

  • Targeting MRTF/SRF in CAP2-dependent dilated cardiomyopathy delays disease onset. / 21.03.2019 / PubMed / Full text

CAPRIN1

  • Reduced Levels of the Synaptic Functional Regulator FMRP in Dentate Gyrus of the Aging Sprague-Dawley Rat. / 2017 / PubMed / Full text

CARF

  • Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential. / 22.05.2020 / PubMed / Full text

CARM1

  • CARM1 regulates senescence during airway epithelial cell injury in COPD pathogenesis. / 01.11.2019 / PubMed / Full text

CASK

  • Integrated study on comparative transcriptome and skeletal muscle function in aged rats. / 01.2018 / PubMed / Full text

CASP3

  • Does cartilage ERα overexpression correlate with osteoarthritic chondrosenescence? Indications from [i]Labisia pumila[/i] OA mitigation. / 09.2019 / PubMed

CASS4

  • Genetic Biomarkers on Age-Related Cognitive Decline. / 2017 / PubMed / Full text

CAV1

  • Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine. / 24.04.2019 / PubMed / Full text

CBX3

  • Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development. / 24.09.2020 / PubMed / Full text

CBX4

  • Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis. / 26.03.2019 / PubMed / Full text

CBX8

  • PIM1-catalyzed CBX8 phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast. / 27.06.2018 / PubMed / Full text

CCAR2

  • CCAR-1 is a negative regulator of the heat-shock response in Caenorhabditis elegans. / 10.2018 / PubMed / Full text

CCDC88A

  • Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

CCL13

  • Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text

CCL18

  • Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text

CCL19

  • Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention. / 16.09.2019 / PubMed / Full text

CCL28

  • Age-related chemokine alterations affect IgA secretion and gut immunity in female mice. / 10.2020 / PubMed / Full text

CCN4

  • CCN proteins as potential actionable targets in scleroderma. / 01.2019 / PubMed / Full text

CCNA1

  • Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. / 02.10.2017 / PubMed / Full text

CCNA2

  • Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan. / 31.03.2018 / PubMed / Full text

CCND1

  • Effects of hydrogen peroxide, doxorubicin and ultraviolet irradiation on senescence of human dental pulp stem cells. / 09.2020 / PubMed / Full text

CCND2

  • Oxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma. / 10.2018 / PubMed / Full text

CCND3

  • The effect of aging on the biological and immunological characteristics of periodontal ligament stem cells. / 29.07.2020 / PubMed / Full text

CCR3

  • Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro. / 04.02.2020 / PubMed / Full text

CD2

  • Adaptive NKG2C CD57 Natural Killer Cell and Tim-3 Expression During Viral Infections. / 2018 / PubMed / Full text

CD209

  • Comparative analysis of microbial sensing molecules in mucosal tissues with aging. / 03.2018 / PubMed / Full text

CD226

  • T-cell Immunoglobulin and ITIM Domain Contributes to CD8 T-cell Immunosenescence. / 04.2018 / PubMed / Full text

CD2AP

  • Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text

CD48

  • Genetic overexpression of COMP-Ang1 impairs BM microenvironment and induces senescence of BM HSCs. / 15.05.2018 / PubMed / Full text

CD55

  • Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia. / 15.11.2018 / PubMed / Full text

CD59

  • Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria. / 2019 / PubMed / Full text

CD72

  • Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation. / 2019 / PubMed / Full text

CD82

  • Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis. / 01.11.2018 / PubMed / Full text

CDC20

  • Premature aging syndrome showing random chromosome number instabilities with CDC20 mutation. / 11.2020 / PubMed / Full text

CDC25A

  • Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage. / 10.10.2020 / PubMed / Full text

CDC6

  • A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence. / 10.01.2018 / PubMed / Full text

CDC73

  • Down-regulation of cancer-associated gene CDC73 contributes to cellular senescence. / 23.05.2018 / PubMed / Full text

CDH1

  • Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation. / 15.09.2020 / PubMed / Full text

CDH2

  • CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type. / 30.11.2018 / PubMed / Full text

CDKN1B

  • A Novel [i]Dnmt3a1[/i] Transcript Inhibits Adipogenesis. / 2018 / PubMed / Full text

CDKN1C

  • Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text

CDO1

  • The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway. / 19.09.2018 / PubMed / Full text

CDR1

  • Two Distinct Pathways in Mice Generate Antinuclear Antigen-Reactive B Cell Repertoires. / 2018 / PubMed / Full text

CDX2

  • Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. / 08.07.2019 / PubMed / Full text

CEBPB

  • Integrative Analysis of Hippocampus Gene Expression Profiles Identifies Network Alterations in Aging and Alzheimer's Disease. / 2018 / PubMed / Full text

CEBPD

  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

CEL

  • Nanocarrier-Mediated Chemo-Immunotherapy Arrested Cancer Progression and Induced Tumor Dormancy in Desmoplastic Melanoma. / 28.08.2018 / PubMed / Full text

CES1

  • [Comparative Study of Hydrolase Activity in Skin with Liver and Intestine, and Its Aging Relation of Carboxylesterase Expression in Cynomolgus Monkey and Beagle Dog]. / 2019 / PubMed / Full text

CETP

  • Biomarkers and Gene Polymorphisms in Members of Long- and Short-lived Families: A Longevity Study. / 2018 / PubMed / Full text

CFB

  • The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. / 13.06.2018 / PubMed / Full text

CFH

  • The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye. / 13.06.2018 / PubMed / Full text

CHAT

  • Satisfaction and Technology Evaluation of a Telehealth Robotic Program to Optimize Healthy Independent Living for Older Adults. / 11.2018 / PubMed / Full text

CHEK2

  • A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text

CHIA

  • Lipoprotein Profile in Aged Rats Fed Chia Oil- or Hydroxytyrosol-Enriched Pork in High Cholesterol/High Saturated Fat Diets. / 26.11.2018 / PubMed / Full text

CHL1

  • Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B. / 07.08.2019 / PubMed / Full text

CHRM4

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

CHRNA7

  • Associations between genetic variations and global motion perception. / 10.2019 / PubMed / Full text

CHRNE

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

CHSY1

  • Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in [i]skt[/i] Mice. / 01.2020 / PubMed / Full text

CINP

  • Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging. / 01-03.2019 / PubMed / Full text

CIP2A

  • Inhibition of CIP2A attenuates tumor progression by inducing cell cycle arrest and promoting cellular senescence in hepatocellular carcinoma. / 08.01.2018 / PubMed / Full text

CIZ1

  • DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice. / 02.2018 / PubMed / Full text

CLEC3B

  • CLEC3B p.S106G Mutant in a Caucasian Population of Successful Neurological Aging. / 16.09.2020 / PubMed / Full text

CLEC4E

  • Comparative analysis of microbial sensing molecules in mucosal tissues with aging. / 03.2018 / PubMed / Full text

CLN3

  • SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

CNP

  • Environmental Enrichment Elicits a Transient Rise of Bioactive C-Type Natriuretic Peptide in Young but Not Aged Rats. / 2018 / PubMed / Full text

CNTF

  • Absence of axonal sprouting following unilateral lesion in 125-day-old rat supraoptic nucleus may be due to age-dependent decrease in protein levels of ciliary neurotrophic factor receptor alpha. / 01.10.2019 / PubMed / Full text

CNTNAP2

  • Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text

COL12A1

  • Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

COL13A1

  • [Alu insertion-deletion polymorphism of COL13A1 and LAMA2 genes: The analysis of association with longevity]. / 10.2016 / PubMed

COL1A1

  • Remodeling process in bone of aged rats in response to resistance training. / 01.09.2020 / PubMed / Full text

COL2A1

  • Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis. / 08.02.2018 / PubMed / Full text

COL6A1

  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

COQ5

  • Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text

COQ6

  • Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text

COQ7

  • Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text

COQ9

  • Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis. / 18.09.2018 / PubMed / Full text

CPNE1

  • Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence. / 04.12.2020 / PubMed / Full text

CPT1A

  • Alteration of fatty acid oxidation by increased CPT1A on replicative senescence of placenta-derived mesenchymal stem cells. / 03.01.2020 / PubMed / Full text

CPT1B

  • Effects of carnitine palmitoyltransferases on cancer cellular senescence. / 02.2019 / PubMed / Full text

CPT2

  • The phytochemical epigallocatechin gallate prolongs the lifespan by improving lipid metabolism, reducing inflammation and oxidative stress in high-fat diet-fed obese rats. / 09.2020 / PubMed / Full text

CR2

  • Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text

CRBN

  • Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity. / 24.04.2020 / PubMed / Full text

CREB1

  • Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons. / 29.08.2018 / PubMed / Full text

CREB5

  • Cellular senescence induces replication stress with almost no affect on DNA replication timing. / 2018 / PubMed / Full text

CREBBP

  • Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. / 22.07.2019 / PubMed / Full text

CREM

  • Ageing in men with normal spermatogenesis alters spermatogonial dynamics and nuclear morphology in Sertoli cells. / 11.2019 / PubMed / Full text

CRISPLD2

  • A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text

CRY2

  • Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text

CRYAB

  • Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells. / 28.12.2018 / PubMed / Full text

CSAD

  • The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway. / 19.09.2018 / PubMed / Full text

CSF3R

  • Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text

CTC1

CTNS

  • Reducing INS-IGF1 signaling protects against non-cell autonomous vesicle rupture caused by SNCA spreading. / 05.2020 / PubMed / Full text

CTSA

  • A CTSA-based consultation service to advance research on special and underserved populations. / 16.01.2020 / PubMed / Full text

CTSL

  • Cathepsin L deficiency results in reactive oxygen species (ROS) accumulation and vascular cells activation. / 12.2017 / PubMed / Full text

CTSS

  • SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

CUL3

  • KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text

CUX1

  • Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text

CXCL13

  • RNA-seq data from C-X-C chemokine receptor type 5 (CXCR5) gene knockout aged mice with retinal degeneration phenotype. / 08.2020 / PubMed / Full text

CXCL14

  • Identification of genes associated with endometrial cell aging. / 01.12.2020 / PubMed / Full text

CXCL16

  • CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4 T-Cell-Dependent Control of Senescence. / 05.2019 / PubMed / Full text

CXCL17

  • [Age-related aspects of the involvement of heat shock proteins in the pathogenesis of osteoarthritis]. / 2017 / PubMed

CXCR1

  • Harmful neutrophil subsets in patients with ischemic stroke: Association with disease severity. / 07.2019 / PubMed / Full text

CXCR5

  • Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses. / 17.08.2017 / PubMed / Full text

CXCR6

  • CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4 T-Cell-Dependent Control of Senescence. / 05.2019 / PubMed / Full text

CYB5A

  • 11-Oxygenated C19 Steroids Do Not Decline With Age in Women. / 01.07.2019 / PubMed / Full text

CYB5R3

  • Overexpression of CYB5R3 and NQO1, two NAD -producing enzymes, mimics aspects of caloric restriction. / 08.2018 / PubMed / Full text

CYP11B1

  • Intratumoral heterogeneity of the tumor cells based on in situ cortisol excess in cortisol-producing adenomas; ∼An association among morphometry, genotype and cellular senescence∼. / 11.2020 / PubMed / Full text

CYP11B2

  • Expression of aldosterone synthase CYP11B2 was inversely correlated with longevity. / 07.2019 / PubMed / Full text

CYP17A1

  • Combined toxicity of endosulfan and phenanthrene mixtures and induced molecular changes in adult Zebrafish (Danio rerio). / 03.2018 / PubMed / Full text

CYP19A1

  • Vitamin D3 mediated regulation of steroidogenesis mitigates testicular activity in an aged rat model. / 06.2019 / PubMed / Full text

CYP1B1

  • Bisphenol A induces DSB-ATM-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts. / 04.2018 / PubMed / Full text

CYP24A1

  • Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism. / 22.02.2018 / PubMed / Full text

CYP26A1

  • Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text

CYP26B1

  • Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia. / 20.05.2020 / PubMed / Full text

CYP2C9

  • Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis. / 12.2017 / PubMed / Full text

CYP2R1

  • Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated With Reduced Hepatic Cyp2r1 Abundance. / 01.08.2018 / PubMed / Full text

CYP3A5

  • Effect of Age and Allele Variants of CYP3A5, CYP3A4, and POR Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. / 12.2017 / PubMed / Full text

DAP

  • Examining changes in the equity of physician distribution in Japan: a specialty-specific longitudinal study. / 08.01.2018 / PubMed / Full text

DAPK2

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

DAXX

  • ATRX-DAXX Complex Expression Levels and Telomere Length in Normal Young and Elder Autopsy Human Brains. / 09.2019 / PubMed / Full text

DAZL

  • DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions. / 30.10.2018 / PubMed / Full text

DBH

  • ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children. / 04.2019 / PubMed / Full text

DBT

  • Diurnal rhythms of heart and respiratory rates in donkeys of different age groups during the cold-dry and hot-dry seasons in a tropical savannah. / 09.2018 / PubMed / Full text

DCAF17

  • Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. / 15.06.2018 / PubMed / Full text

DCLRE1C

  • Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population. / 06.2019 / PubMed / Full text

DCTN2

  • Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text

DCTN3

  • Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text

DCTN6

  • Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text

DDI2

  • Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. / 01.08.2018 / PubMed / Full text

DDIT3

  • Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text

DDR1

  • Age-related modifications of type I collagen impair DDR1-induced apoptosis in non-invasive breast carcinoma cells. / 2018 / PubMed / Full text

DDR2

  • Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging. / 03.2018 / PubMed / Full text

DEPDC5

  • KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text

DEPTOR

DES

  • Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis. / 20.03.2018 / PubMed / Full text

DGAT1

  • Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPα-p300/DGAT1 pathway. / 02.2018 / PubMed / Full text

DGAT2

  • Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text

DGCR8

  • HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif. / 29.04.2019 / PubMed / Full text

DHRS2

  • Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts. / 08.05.2018 / PubMed / Full text

DIAPH1

  • Diaphanous 1 (DIAPH1) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer's Disease. / 2018 / PubMed / Full text

DIP2A

DKK2

  • Low Serum Levels of DKK2 Predict Incident Low-Impact Fracture in Older Women. / 07.2019 / PubMed / Full text

DLAT

  • Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

DLC1

  • Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells. / 15.09.2018 / PubMed / Full text

DLGAP2

  • Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. / 01.09.2020 / PubMed / Full text

DLL1

  • MiR-34a Enhances Chondrocyte Apoptosis, Senescence and Facilitates Development of Osteoarthritis by Targeting DLL1 and Regulating PI3K/AKT Pathway. / 2018 / PubMed / Full text

DLL4

  • Dynamic regulation of NOTCH1 activation and Notch ligand expression in human thymus development. / 13.08.2018 / PubMed / Full text

DMP1

  • Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice. / 07.2018 / PubMed / Full text

DMPK

  • Expanded CUG Repeats Trigger Disease Phenotype and Expression Changes through the RNAi Machinery in C. elegans. / 19.04.2019 / PubMed / Full text

DNAJB9

  • DNAJB9 Inhibits p53-Dependent Oncogene-Induced Senescence and Induces Cell Transformation. / 30.04.2020 / PubMed / Full text

DNM1

  • Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice. / 2018 / PubMed / Full text

DNM2

  • Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy. / 19.11.2018 / PubMed / Full text

DNMT3L

  • Transient DNMT3L Expression Reinforces Chromatin Surveillance to Halt Senescence Progression in Mouse Embryonic Fibroblast. / 2020 / PubMed / Full text

DOCK11

  • [Immunosenescence: The Forefront of Infection and Trophic Control]. / 2020 / PubMed / Full text

DOT1L

  • Metformin regulates mitochondrial biogenesis and senescence through AMPK mediated H3K79 methylation: Relevance in age-associated vascular dysfunction. / 04.2018 / PubMed / Full text

DPP6

  • A novel structure associated with aging is augmented in the DPP6-KO mouse brain. / 23.11.2020 / PubMed / Full text

DPT

  • Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography. / 12.2017 / PubMed / Full text

DPYSL2

  • Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. / 2019 / PubMed / Full text

DRAM1

  • Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. / 12.2019 / PubMed / Full text

DRAM2

  • SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

DRD1

  • Impact of dopamine-related genetic variants on physical activity in old age - a cohort study. / 24.05.2020 / PubMed / Full text

DRD4

  • ADHD risk genes involved in dopamine signaling and metabolism are associated with reduced estimated life expectancy at young adult follow-up in hyperactive and control children. / 04.2019 / PubMed / Full text

DROSHA

  • Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. / 06.2018 / PubMed / Full text

DSC1

  • HDLs and the pathogenesis of atherosclerosis. / 05.2018 / PubMed / Full text

DSCAM

  • Age- and speed-dependent modulation of gaits in DSCAM mutant mice. / 01.02.2018 / PubMed / Full text

DSE

  • Impact of Intensive Lifestyle Intervention on Disability-Free Life Expectancy: The Look AHEAD Study. / 05.2018 / PubMed / Full text

DSPP

  • Effects of [i]p[/i]-Cresol on Senescence, Survival, Inflammation, and Odontoblast Differentiation in Canine Dental Pulp Stem Cells. / 21.09.2020 / PubMed / Full text

DTL

  • Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells. / 2018 / PubMed / Full text

DTNBP1

  • Genetic Biomarkers on Age-Related Cognitive Decline. / 2017 / PubMed / Full text

DUSP1

  • miR-1468-3p Promotes Aging-Related Cardiac Fibrosis. / 05.06.2020 / PubMed / Full text

DUSP2

  • Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism. / 2019 / PubMed / Full text

DUSP8

  • MiR-21-5p/dual-specificity phosphatase 8 signalling mediates the anti-inflammatory effect of haem oxygenase-1 in aged intracerebral haemorrhage rats. / 12.2019 / PubMed / Full text

DUT

  • Simultaneous liquefaction, saccharification, and fermentation of L-lactic acid using aging paddy rice with hull by an isolated thermotolerant Enterococcus faecalis DUT1805. / 09.2020 / PubMed / Full text

DYNC2H1

  • Role for intraflagellar transport in building a functional transition zone. / 12.2018 / PubMed / Full text

DYRK1A

  • Altered age-linked regulation of plasma DYRK1A in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load. / 2020 / PubMed / Full text

E2F3

  • Time-course transcriptome analysis of medullary thymic epithelial cells in the early phase of thymic involution. / 07.2018 / PubMed / Full text

ECM1

  • Novel role of extracellular matrix protein 1 (ECM1) in cardiac aging and myocardial infarction. / 2019 / PubMed / Full text

ECRG4

ECSIT

  • Longevity-related molecular pathways are subject to midlife "switch" in humans. / 08.2019 / PubMed / Full text

EDEM1

  • Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text

EDF1

  • Silencing of FOREVER YOUNG FLOWER Like Genes from Phalaenopsis Orchids Promotes Flower Senescence and Abscission. / 25.11.2020 / PubMed / Full text

EDN1

  • Dexamethasone downregulates SIRT1 and IL6 and upregulates EDN1 genes in stem cells derived from gingivae via the AGE/RAGE pathway. / 03.2018 / PubMed / Full text

EED

  • Economic evaluations of eHealth technologies: A systematic review. / 2018 / PubMed / Full text

EFEMP1

  • A novel age-related venous amyloidosis derived from EGF-containing fibulin-like extracellular matrix protein 1. / 04.2019 / PubMed / Full text

EHF

  • Extended high frequency hearing and speech perception implications in adults and children. / 11.2020 / PubMed / Full text

EID3

  • Upregulation of EID3 sensitizes breast cancer cells to ionizing radiation-induced cellular senescence. / 11.2018 / PubMed / Full text

EIF2B1

  • Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

EIF2B2

  • Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

EIF2B3

  • Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

EIF2B4

  • Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

EIF2B5

  • Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

EIF4E

  • Transcriptomic evidence that insulin signalling pathway regulates the ageing of subterranean termite castes. / 18.05.2020 / PubMed / Full text

ELANE

  • Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text

ELF3

  • High Ambient Temperature Accelerates Leaf Senescence via PHYTOCHROME-INTERACTING FACTOR 4 and 5 in [i]Arabidopsis[/i]. / 31.07.2020 / PubMed / Full text

ELL

  • Exceptional Longevity and Polygenic Risk for Cardiovascular Health. / 18.03.2019 / PubMed / Full text

ELOVL6

  • An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. / 06.2019 / PubMed / Full text

EML6

  • Cell fate regulation by reticulon-4 in human prostate cancers. / 07.2019 / PubMed / Full text

ENC1

  • Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text

ENO1

  • Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells. / 2020 / PubMed / Full text

ENTPD7

  • Inhibition of lung cancer cells and Ras/Raf/MEK/ERK signal transduction by ectonucleoside triphosphate phosphohydrolase-7 (ENTPD7). / 23.08.2019 / PubMed / Full text

EPG5

  • Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom. / 05.2018 / PubMed / Full text

EPHA1

  • Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text

EPHA2

ERAP1

  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

ERBB4

  • Overexpression of ERBB4 rejuvenates aged mesenchymal stem cells and enhances angiogenesis via PI3K/AKT and MAPK/ERK pathways. / 03.2019 / PubMed / Full text

ERCC2

  • The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text

ERCC5

  • Identification of a ERCC5 c.2333T>C (L778P) Variant in Two Tunisian Siblings With Mild Xeroderma Pigmentosum Phenotype. / 2019 / PubMed / Full text

ERCC6

  • Two Cockayne Syndrome patients with a novel splice site mutation - clinical and metabolic analyses. / 10.2018 / PubMed / Full text

ERCC8

  • Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts. / 12.2019 / PubMed / Full text

ESPL1

  • Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants. / 09.2020 / PubMed / Full text

ESR1

  • Menopause and adipose tissue: miR-19a-3p is sensitive to hormonal replacement. / 05.01.2018 / PubMed / Full text

ESRG

  • MYC Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition. / 10.04.2018 / PubMed / Full text

ETV5

  • miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. / 06.2018 / PubMed / Full text

ETV6

  • FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence. / 01.2019 / PubMed / Full text

EVL

  • Health Years in Total: A New Health Objective Function for Cost-Effectiveness Analysis. / 01.2020 / PubMed / Full text

EWSR1

  • EWSR1, a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways. / 01.07.2019 / PubMed / Full text

EXD2

  • EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. / 02.2018 / PubMed / Full text

EXO1

  • Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population. / 06.2019 / PubMed / Full text

EXOC7

  • PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. / 09.07.2018 / PubMed / Full text

EZR

  • Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model. / 03.2018 / PubMed / Full text

F10

  • Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-F10 cells by inducing senescence. / 15.07.2018 / PubMed / Full text

F12

  • Multigenerational effects of carbendazim in Daphnia magna: From a subcellular to a population level. / 02.2019 / PubMed / Full text

FA2H

  • C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production. / 2018 / PubMed / Full text

FABP1

  • Expression of digestive enzyme and intestinal transporter genes during chronic heat stress in the thermally manipulated broiler chicken. / 01.09.2019 / PubMed / Full text

FADD

  • Improved age-related deficits in cognitive performance and affective-like behavior following acute, but not repeated, 8-OH-DPAT treatments in rats: regulation of hippocampal FADD. / 11.2018 / PubMed / Full text

FADS1

  • Aging and FADS1 polymorphisms decrease the biosynthetic capacity of long-chain PUFAs: A human trial using [U- C]linoleic acid. / 09.2019 / PubMed / Full text

FAH

  • Oxaloacetate decarboxylase FAHD1 - a new regulator of mitochondrial function and senescence. / 01.2019 / PubMed / Full text

FAHD1

  • Oxaloacetate decarboxylase FAHD1 - a new regulator of mitochondrial function and senescence. / 01.2019 / PubMed / Full text

FAM13A

  • Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive pulmonary disease. / 05.2018 / PubMed / Full text

FANCC

  • Fanconi Anemia complementation group C protein in metabolic disorders. / 21.06.2018 / PubMed / Full text

FAR2

FASN

  • Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text

FBN2

  • Assessment of Human Skin Gene Expression by Different Blends of Plant Extracts with Implications to Periorbital Skin Aging. / 26.10.2018 / PubMed / Full text

FBXO31

  • The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence. / 19.10.2018 / PubMed / Full text

FBXO46

  • The SCF ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence. / 19.10.2018 / PubMed / Full text

FCER1G

  • A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. / 2019 / PubMed / Full text

FCGR2A

  • Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells. / 03.08.2019 / PubMed / Full text

FDPS

  • Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes. / 12.2018 / PubMed / Full text

FER

  • Tracking the recognition of static and dynamic facial expressions of emotion across the life span. / 04.09.2018 / PubMed / Full text

FER1L6

  • Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

FEZ1

  • Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice. / 19.09.2017 / PubMed / Full text

FGF6

  • Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. / 06.02.2019 / PubMed / Full text

FGFR2

  • Oncogenic mutations in histologically normal endometrium: the new normal? / 10.2019 / PubMed / Full text

FKBP5

  • Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk. / 04.06.2019 / PubMed / Full text

FLT3

  • Sequential acquisition of mutations in myelodysplastic syndromes. / 2017 / PubMed / Full text

FMO3

  • Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver. / 11.2017 / PubMed / Full text

FMR1

  • Static and dynamic postural control deficits in aging fragile X mental retardation 1 (FMR1) gene premutation carriers. / 21.01.2019 / PubMed / Full text

FNTA

  • The Hip Morphology Changes with Ageing in Asian Population. / 2018 / PubMed / Full text

FOSL2

  • LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis. / 03.04.2020 / PubMed / Full text

FOXC1

  • Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text

FOXD1

  • MicroRNA-338-5p plays a tumor suppressor role in glioma through inhibition of the MAPK-signaling pathway by binding to FOXD1. / 12.2018 / PubMed / Full text

FOXL2

  • Human amniotic mesenchymal stem cells improve ovarian function in natural aging through secreting hepatocyte growth factor and epidermal growth factor. / 09.03.2018 / PubMed / Full text

FOXN1

  • Thymic rejuvenation via FOXN1-reprogrammed embryonic fibroblasts (FREFs) to counteract age-related inflammation. / 17.09.2020 / PubMed / Full text

FOXP2

  • Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization. / 06.11.2018 / PubMed / Full text

FOXP4

  • Identification of the neurotransmitter profile of AmFoxP expressing neurons in the honeybee brain using double-label in situ hybridization. / 06.11.2018 / PubMed / Full text

FRG1

  • Intergenerational response of steroidogenesis-related genes to maternal malnutrition. / 10.2019 / PubMed / Full text

FRG2

  • Intergenerational response of steroidogenesis-related genes to maternal malnutrition. / 10.2019 / PubMed / Full text

FSTL1

FZD4

  • MiR-1292 Targets FZD4 to Regulate Senescence and Osteogenic Differentiation of Stem Cells in TE/SJ/Mesenchymal Tissue System via the Wnt/β-catenin Pathway. / 12.2018 / PubMed / Full text

G6PC

  • Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of TP53. / 11.2018 / PubMed / Full text

G6PC3

  • Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text

GAB2

  • Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936. / 01.12.2017 / PubMed / Full text

GABARAP

  • Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. / 18.08.2020 / PubMed / Full text

GADD45B

  • Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging? / 2019 / PubMed / Full text

GALC

  • Analysis of age-related changes in psychosine metabolism in the human brain. / 2018 / PubMed / Full text

GATA1

  • Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass. / 10.2019 / PubMed / Full text

GATA6

  • GATA Regulation and Function During the Ovarian Life Cycle. / 2018 / PubMed / Full text

GCAT

  • Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis. / 03.04.2018 / PubMed / Full text

GCK

  • The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing. / 12.2019 / PubMed / Full text

GCNT2

  • Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text

GDA

  • Comparison of the Shear Bond Strength of Metal Orthodontic Brackets Bonded to Long-term Water-aged and Fresh Porcelain and Composite Surfaces. / 03.2019 / PubMed / Full text

GDF5

  • An embryonic CaVβ1 isoform promotes muscle mass maintenance via GDF5 signaling in adult mouse. / 06.11.2019 / PubMed / Full text

GDF9

  • Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. / 18.10.2017 / PubMed / Full text

GEN1

  • US acculturation and poor sleep among an intergenerational cohort of adult Latinos in Sacramento, California. / 01.03.2019 / PubMed / Full text

GFRAL

  • Growth differentiation factor 15 (GDF15): A survival protein with therapeutic potential in metabolic diseases. / 06.2019 / PubMed / Full text

GGCX

  • Multiple Modes of Vitamin K Actions in Aging-Related Musculoskeletal Disorders. / 11.06.2019 / PubMed / Full text

GHSR

  • The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text

GIT1

GJA8

  • The impact of GJA8 SNPs on susceptibility to age-related cataract. / 12.2018 / PubMed / Full text

GJC2

  • Zebrafish brain RNA sequencing reveals that cell adhesion molecules are critical in brain aging. / 10.2020 / PubMed / Full text

GLA

  • TLR-adjuvanted nanoparticle vaccines differentially influence the quality and longevity of responses to malaria antigen Pfs25. / 17.05.2018 / PubMed / Full text

GLI1

  • Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text

GLO1

  • The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases. / 2017 / PubMed / Full text

GNAQ

  • GNAQ expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system. / 01.2020 / PubMed / Full text

GNE

  • Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2 mice. / 10.12.2020 / PubMed / Full text

GNG4

  • Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes. / 05.2018 / PubMed / Full text

GNPAT

  • Plasmalogens Inhibit Endocytosis of Toll-like Receptor 4 to Attenuate the Inflammatory Signal in Microglial Cells. / 05.2019 / PubMed / Full text

GORAB

  • Examining tissue composition, whole-bone morphology and mechanical behavior of Gorab mice tibiae: A mouse model of premature aging. / 08.12.2017 / PubMed / Full text

GOT1

  • Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text

GP1BA

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

GP6

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

GPBAR1

  • Activation of the bile acid receptor GPBAR1 (TGR5) ameliorates interleukin-1β (IL-1β)- induced chondrocytes senescence. / 10.2018 / PubMed / Full text

GPC1

  • Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing. / 15.10.2019 / PubMed / Full text

GPD2

  • Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. / 06.2018 / PubMed / Full text

GPR101

  • Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent. / 2017 / PubMed / Full text

GPR158

  • RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss. / 23.10.2018 / PubMed / Full text

GPR173

  • Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent. / 2017 / PubMed / Full text

GPR19

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

GPR37

  • Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. / 08.2018 / PubMed / Full text

GPR37L1

  • Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. / 08.2018 / PubMed / Full text

GPR6

  • Accelerated Epigenetic Aging and Methylation Disruptions Occur in Human Immunodeficiency Virus Infection Prior to Antiretroviral Therapy. / 22.09.2020 / PubMed / Full text

GPX2

  • RNA Exosome Complex-Mediated Control of Redox Status in Pluripotent Stem Cells. / 10.10.2017 / PubMed / Full text

GPX3

  • Long noncoding RNA glutathione peroxidase 3-antisense inhibits lens epithelial cell apoptosis by upregulating glutathione peroxidase 3 expression in age-related cataract. / 2019 / PubMed / Full text

GPX7

  • Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7. / 08.2018 / PubMed / Full text

GRB10

  • De-silencing [i]Grb10[/i] contributes to acute ER stress-induced steatosis in mouse liver. / 05.2018 / PubMed / Full text

GRB2

  • Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via IRS1/GRB2/ SOS1, GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice. / 21.01.2019 / PubMed / Full text

GREM1

  • GREM1 inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells. / 09.03.2020 / PubMed / Full text

GREM2

  • Increase of gremlin 2 with age in human adipose-derived stromal/stem cells and its inhibitory effect on adipogenesis. / 12.2019 / PubMed / Full text

GRID1

  • Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. / 03.2020 / PubMed / Full text

GRIN2B

  • Medial temporal lobe atrophy relates more strongly to sleep-wake rhythm fragmentation than to age or any other known risk. / 04.2019 / PubMed / Full text

GRK4

  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text

GRK6

  • Age-dependent effects of dopamine receptor inactivation on cocaine-induced behaviors in male rats: Evidence of dorsal striatal D2 receptor supersensitivity. / 12.2019 / PubMed / Full text

GRM2

  • Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

GRM3

  • Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk. / 04.2020 / PubMed / Full text

GSN

  • Oral administration of alcalase potato protein hydrolysate-APPH attenuates high fat diet-induced cardiac complications via TGF-β/GSN axis in aging rats. / 01.2019 / PubMed / Full text

GSTA1

  • Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GSTK1

  • Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GSTM2

  • Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage. / 07.07.2020 / PubMed / Full text

GSTM3

  • Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GSTO1

  • Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GSTP1

  • Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GSTT1

  • Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GSTT2

  • Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GSTZ1

  • Age-associated changes in GSH S-transferase gene/proteins in livers of rats. / 12.2018 / PubMed / Full text

GUK1

  • Characterization of the impact of GMP/GDP synthesis inhibition on replicative lifespan extension in yeast. / 08.2020 / PubMed / Full text

GYS2

  • In ovo feeding of creatine pyruvate modulates growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of embryos and neonatal broilers. / 04.2018 / PubMed / Full text

GZMK

  • Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK CD8 T Cells as Conserved Hallmark of Inflammaging. / 21.11.2020 / PubMed / Full text

HADHA

  • Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells. / 2019 / PubMed / Full text

HAMP

  • A potent tilapia secreted granulin peptide enhances the survival of transgenic zebrafish infected by Vibrio vulnificus via modulation of innate immunity. / 04.2018 / PubMed / Full text

HAP1

  • The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer. / 20.06.2018 / PubMed / Full text

HAS2

  • Age-related changes in cyclic phosphatidic acid-induced hyaluronic acid synthesis in human fibroblasts. / 01.2018 / PubMed / Full text

HAX1

  • Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text

HBD

  • Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection. / 2019 / PubMed / Full text

HBM

  • The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis. / 25.09.2019 / PubMed / Full text

HCN4

  • Structural and functional remodeling of the atrioventricular node with aging in rats: The role of hyperpolarization-activated cyclic nucleotide-gated and ryanodine 2 channels. / 05.2018 / PubMed / Full text

HCRT

  • Age-related central regulation of orexin and NPY in the short-lived African killifish Nothobranchius furzeri. / 15.05.2019 / PubMed / Full text

HDAC10

  • Middle-aged female rats lack changes in histone H3 acetylation in the anterior hypothalamus observed in young females on the day of a luteinizing hormone surge. / 17.09.2019 / PubMed / Full text

HDAC11

  • Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice. / 19.09.2017 / PubMed / Full text

HDAC8

  • Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri. / 09.2018 / PubMed / Full text

HDC

  • Induced pluripotency and spontaneous reversal of cellular aging in supercentenarian donor cells. / 07.05.2020 / PubMed / Full text

HES1

  • A Single-Cell Transcriptomic Atlas of Human Skin Aging. / 23.11.2020 / PubMed / Full text

HHLA2

  • Impaired Cytolytic Activity and Loss of Clonal Neoantigens in Elderly Patients With Lung Adenocarcinoma. / 05.2019 / PubMed / Full text

HIF1A

  • Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text

HIF3A

  • Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text

HIRA

  • Pak2 kinase promotes cellular senescence and organismal aging. / 02.07.2019 / PubMed / Full text

HJV

  • Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting. / 06.2019 / PubMed / Full text

HK2

  • Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury. / 11.01.2018 / PubMed / Full text

HLA-DMA

  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

HLA-DPA1

  • 17th IHIW component "Immunogenetics of Ageing" - New NGS data. / 09.2019 / PubMed / Full text

HLA-DQA1

  • 17th IHIW component "Immunogenetics of Ageing" - New NGS data. / 09.2019 / PubMed / Full text

HLA-DQB1

  • Identification of new genetic variants of HLA-DQB1 associated with human longevity and lipid homeostasis-a cross-sectional study in a Chinese population. / 10.11.2017 / PubMed / Full text

HLA-DRB1

  • The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle. / 11.2020 / PubMed / Full text

HLA-E

  • Senescent cells evade immune clearance via HLA-E-mediated NK and CD8 T cell inhibition. / 03.06.2019 / PubMed / Full text

HMGA1

  • Characterization of [i]HMGA1P6[/i] transgenic mouse embryonic fibroblasts. / 09.2020 / PubMed / Full text

HMGCS1

  • The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain. / 15.10.2018 / PubMed / Full text

HNF4A

  • Hepatocyte Nuclear Factor-4α P2 Promoter Variants Are Associated With the Risk of Metabolic Syndrome and Testosterone Deficiency in Aging Taiwanese Men. / 11.2018 / PubMed / Full text

HNRNPA0

  • The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. / 10.2019 / PubMed / Full text

HNRNPA1

  • HNRNPA1-mediated 3' UTR length changes of [i]HN1[/i] contributes to cancer- and senescence-associated phenotypes. / 30.06.2019 / PubMed / Full text

HNRNPM

  • The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. / 10.2019 / PubMed / Full text

HOXA3

  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

HOXA4

  • Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes. / 10.2019 / PubMed / Full text

HOXB7

  • Impact of HOXB7 overexpression on human adipose-derived mesenchymal progenitors. / 19.03.2019 / PubMed / Full text

HOXC4

  • Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

HOXD8

  • Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts. / 2020 / PubMed / Full text

HPD

  • Protein-Amino Acid Metabolism Disarrangements: The Hidden Enemy of Chronic Age-Related Conditions. / 22.03.2018 / PubMed / Full text

HPSE

  • Distribution of heparan sulfate correlated with the expression of heparanase-1 and matrix metalloproteinase-9 in an ovariectomized rats skin. / 07.2020 / PubMed / Full text

HRG

  • Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice. / 10.2017 / PubMed / Full text

HRH4

  • Histamime Receptor H4 as a New Therapeutic Target for Age-related Macular Degeneration. / 11.2016 / PubMed

HS2ST1

  • Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity. / 31.01.2020 / PubMed / Full text

HSD17B14

  • Bisphenol A induces DSB-ATM-p53 signaling leading to cell cycle arrest, senescence, autophagy, stress response, and estrogen release in human fetal lung fibroblasts. / 04.2018 / PubMed / Full text

HSD17B4

  • Autonomous Purkinje cell axonal dystrophy causes ataxia in peroxisomal multifunctional protein-2 deficiency. / 09.2018 / PubMed / Full text

HSD3B2

  • 11-Oxygenated C19 Steroids Do Not Decline With Age in Women. / 01.07.2019 / PubMed / Full text

HSP90AA1

  • SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

HSPA13

  • Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

HSPA1L

  • Melatonin suppresses senescence-derived mitochondrial dysfunction in mesenchymal stem cells via the HSPA1L-mitophagy pathway. / 03.2020 / PubMed / Full text

HSPA5

  • Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text

HSPB1

  • The beneficial effects of 15 units of high-intensity circuit training in women is modified by age, baseline insulin resistance and physical capacity. / 06.2019 / PubMed / Full text

HSPB6

  • Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

HSPG2

  • Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

HTRA1

  • Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3. / 06.2018 / PubMed / Full text

HYOU1

  • Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression. / 08.2019 / PubMed / Full text

IAPP

  • Protein aggregates and proteostasis in aging: Amylin and β-cell function. / 01.2019 / PubMed / Full text

ICAM1

  • An Inhibitor of Activated Blood Coagulation Factor X Shows Anti-Endothelial Senescence and Anti-Atherosclerotic Effects. / 2019 / PubMed / Full text

ICE1

  • ATBS1-INTERACTING FACTOR 2 negatively regulates dark- and brassinosteroid-induced leaf senescence through interactions with INDUCER OF CBF EXPRESSION 1. / 19.02.2020 / PubMed / Full text

ID2

  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

IFI27

  • Ultraviolet B irradiation-induced keratinocyte senescence and impaired development of 3D epidermal reconstruct. / 01.06.2021 / PubMed / Full text

IFIH1

  • Comparative analysis of microbial sensing molecules in mucosal tissues with aging. / 03.2018 / PubMed / Full text

IFIT1

  • Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text

IFITM1

  • Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection. / 10.11.2018 / PubMed / Full text

IFITM3

  • Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3. / 25.06.2019 / PubMed / Full text

IFNG

  • Glutathione Peroxidase 3 Delivered by hiPSC-MSCs Ameliorated Hepatic IR Injury via Inhibition of Hepatic Senescence. / 2018 / PubMed / Full text

IFT140

IGF2BP3

  • Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth. / 01.05.2019 / PubMed / Full text

IGF2R

  • Insulin-like factor-2 receptor rs9456497 G genotype overrepresents in males of average population and its correlation with cardiovascular risks. / 05-06.2018 / PubMed / Full text

IGFBP4

  • Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey. / 11.10.2019 / PubMed / Full text

IGFBP6

  • Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

IGFBP7

  • Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7. / 03.2020 / PubMed / Full text

IGHD

  • Growth Hormone Deficiency: Health and Longevity. / 01.04.2019 / PubMed / Full text

IGSF1

  • Age-related gene and miRNA expression changes in airways of healthy individuals. / 06.03.2019 / PubMed / Full text

IHH

  • Indian Hedgehog regulates senescence in bone marrow-derived mesenchymal stem cell through modulation of ROS/mTOR/4EBP1, p70S6K1/2 pathway. / 01.04.2020 / PubMed / Full text

IKBKB

  • Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

IL13

  • Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text

IL15

  • Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of IL15. / 27.04.2020 / PubMed / Full text

IL17RA

  • Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon. / 2017 / PubMed / Full text

IL18

IL1R2

  • Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin. / 01.2018 / PubMed / Full text

IL22

  • Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. / 07.2019 / PubMed / Full text

IL2RA

  • Dynamic demethylation of the IL2RA promoter during in vitro CD4+ T cell activation in association with IL2RA expression. / 2018 / PubMed / Full text

IL4

  • Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia. / 01.01.2018 / PubMed / Full text

IL6ST

  • The senescent status of endothelial cells affects proliferation, inflammatory profile and SOX2 expression in bone marrow-derived mesenchymal stem cells. / 06.2019 / PubMed / Full text

IL9

  • Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation. / 08.2019 / PubMed / Full text

ILDR1

  • Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment. / 23.10.2019 / PubMed / Full text

IMMP2L

  • Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. / 06.2018 / PubMed / Full text

ING1

  • Impaired DNA demethylation of C/EBP sites causes premature aging. / 01.06.2018 / PubMed / Full text

INHBA

  • Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

INHBE

  • Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature. / 18.03.2019 / PubMed / Full text

INPP4B

  • [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text

INPP5A

  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

IP6K1

  • The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle. / 2019 / PubMed / Full text

IPMK

  • Inositol Polyphosphate Multikinase ([i]IPMK[/i]), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity. / 08.02.2019 / PubMed / Full text

IRF1

  • Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain. / 06.2018 / PubMed / Full text

IRF5

  • Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice. / 11.2017 / PubMed / Full text

IRGM

  • SIRT6 histone deacetylase functions as a potential oncogene in human melanoma. / 09.2017 / PubMed / Full text

ISG15

  • Transcriptome analysis reveals immune-related gene expression changes with age in giant panda ([i]Ailuropoda melanoleuca[/i]) blood. / 14.01.2019 / PubMed / Full text

ITGA2B

  • Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. / 04.2018 / PubMed / Full text

ITGA3

  • A transcriptomic analysis of serial-cultured, tonsil-derived mesenchymal stem cells reveals decreased integrin α3 protein as a potential biomarker of senescent cells. / 17.08.2020 / PubMed / Full text

ITGA5

  • Kaempferol alleviates the reduction of developmental competence during aging of porcine oocytes. / 11.2019 / PubMed / Full text

ITGA6

  • Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text

ITGAM

  • Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging. / 2019 / PubMed / Full text

ITGB1

  • Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report. / 05.2018 / PubMed / Full text

ITGB2

  • A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. / 2019 / PubMed / Full text

ITGB4

  • ITGB4 deficiency induces senescence of airway epithelial cells through p53 activation. / 03.2019 / PubMed / Full text

ITK

  • Does Tetralogy of Fallot affect brain aging? A proof-of-concept study. / 2018 / PubMed / Full text

ITPR2

  • The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling. / 12.2018 / PubMed / Full text

JAGN1

  • Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death / 13.11.2018 / PubMed / Full text

JAK3

  • Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. / 04.2018 / PubMed / Full text

JAM3

  • Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text

JARID2

  • Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

JDP2

  • Jun dimerization protein 2 controls hypoxia-induced replicative senescence via both the p16 -pRb and Arf-p53 pathways. / 11.2017 / PubMed / Full text

JUNB

  • Promotion of cellular senescence by THG-1/TSC22D4 knockout through activation of JUNB. / 19.02.2020 / PubMed / Full text

KAT6B

  • Aging-associated decrease in the histone acetyltransferase KAT6B is linked to altered hematopoietic stem cell differentiation. / 02.2020 / PubMed / Full text

KCNAB3

  • Tracking age-correlated DNA methylation markers in the young. / 09.2018 / PubMed / Full text

KCNB1

  • Oxidation of KCNB1 potassium channels in the murine brain during aging is associated with cognitive impairment. / 14.05.2019 / PubMed / Full text

KCNC3

  • DNA methylation levels in candidate genes associated with chronological age in mammals are not conserved in a long-lived seabird. / 2017 / PubMed / Full text

KCNE4

  • Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice. / 29.05.2018 / PubMed / Full text

KCNK2

  • Brain age prediction using deep learning uncovers associated sequence variants. / 27.11.2019 / PubMed / Full text

KCNQ2

  • Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes. / 05.2018 / PubMed / Full text

KCNQ4

  • Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss. / 2020 / PubMed / Full text

KCTD12

  • The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort. / 2020 / PubMed / Full text

KDM2A

  • SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair. / 25.06.2020 / PubMed / Full text

KDM2B

  • Identification of Structural Elements of the Lysine Specific Demethylase 2B CxxC Domain Associated with Replicative Senescence Bypass in Primary Mouse Cells. / 06.2020 / PubMed / Full text

KDM3A

  • KDM3A and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization. / 22.11.2019 / PubMed / Full text

KDM4A

  • Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines. / 15.01.2019 / PubMed / Full text

KDM5A

  • Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines. / 15.01.2019 / PubMed / Full text

KDM6B

  • Histone demethylase KDM6B regulates 1,25-dihydroxyvitamin D3-induced senescence in glioma cells. / 08.2019 / PubMed / Full text

KIF1A

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

KIF1B

  • BDNF trafficking and signaling impairment during early neurodegeneration is prevented by moderate physical activity. / 12.2016 / PubMed / Full text

KIFC3

  • Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging. / 08.2018 / PubMed / Full text

KLB

  • Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. / 2018 / PubMed / Full text

KLF1

  • Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis. / 24.08.2018 / PubMed / Full text

KLF2

  • KLF2 induces the senescence of pancreatic cancer cells by cooperating with FOXO4 to upregulate p21. / 01.03.2020 / PubMed / Full text

KLF5

  • EGR1 promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling. / 01.09.2019 / PubMed / Full text

KLF6

  • Krüppel-Like Factor 6 Is Required for Oxidative and Oncogene-Induced Cellular Senescence. / 2019 / PubMed / Full text

KLHL22

  • KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text

KPNA2

  • Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice. / 2019 / PubMed / Full text

KRT15

  • Extracellular proteoglycan decorin maintains human hair follicle stem cells. / 12.2018 / PubMed / Full text

KRT18

  • Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text

KRT19

  • Characterization of Krt19 allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc. / 01.2020 / PubMed / Full text

KY

  • Combination of acupuncture and Chinese herbal formula for elderly adults with mild cognitive impairment: protocol for a randomized controlled trial. / 11.02.2019 / PubMed / Full text

LAG3

  • T Cell Transcriptional Profiling and Immunophenotyping Uncover LAG3 as a Potential Significant Target of Immune Modulation in Multiple Myeloma. / 01.2020 / PubMed / Full text

LAGE3

  • Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text

LAMA2

  • [Alu insertion-deletion polymorphism of COL13A1 and LAMA2 genes: The analysis of association with longevity]. / 10.2016 / PubMed

LAMA5

  • The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. / 05.06.2018 / PubMed / Full text

LAT

  • Is the combined auriculotherapy approach superior to magneto-auriculotherapy alone in aging males with lower urinary tract symptoms? A randomized controlled trial. / 16.01.2019 / PubMed / Full text

LCN2

  • Anthropometric and glucometabolic changes in an aged mouse model of lipocalin-2 overexpression. / 01.2019 / PubMed / Full text

LDB2

  • Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

LDLR

  • Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice. / 08.2018 / PubMed / Full text

LEF1

  • LncRNA H19 targets miR-22 to modulate H O -induced deregulation in nucleus pulposus cell senescence, proliferation, and ECM synthesis through Wnt signaling. / 06.2018 / PubMed / Full text

LGALS3

  • Tissue Taurine Depletion Induces Profibrotic Pattern of Gene Expression and Causes Aging-Related Cardiac Fibrosis in Heart in Mice. / 2018 / PubMed / Full text

LGI1

  • Antibody-associated CNS syndromes without signs of inflammation in the elderly. / 03.10.2017 / PubMed / Full text

LGR6

  • Effect of defensins-containing eye cream on periocular rhytids and skin quality. / 08.2020 / PubMed / Full text

LHCGR

  • Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats. / 11.10.2020 / PubMed / Full text

LIFR

  • Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. / 15.03.2019 / PubMed / Full text

LIN28B

  • Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. / 2017 / PubMed / Full text

LIPA

  • Influence of Habitual Physical Behavior - Sleeping, Sedentarism, Physical Activity - On Bone Health in Community-Dwelling Older People. / 2019 / PubMed / Full text

LMX1A

  • Phenotypic Reprogramming of Striatal Neurons into Dopaminergic Neuron-like Cells in the Adult Mouse Brain. / 13.11.2018 / PubMed / Full text

LOXL1

  • A blackberry-dill extract combination synergistically increases skin elasticity. / 10.2020 / PubMed / Full text

LPAR3

  • Upregulated microRNA-15b alleviates ovarian cancer through inhitbition of the PI3K/Akt pathway by targeting LPAR3. / 12.2019 / PubMed / Full text

LRP1

  • Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome. / 06.2020 / PubMed / Full text

LRP2

  • Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis. / 27.11.2018 / PubMed / Full text

LRP6

  • Low-density lipoprotein receptor-related protein 6-mediated signaling pathways and associated cardiovascular diseases: diagnostic and therapeutic opportunities. / 04.2020 / PubMed / Full text

LRP8

  • SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE. / 02.07.2019 / PubMed / Full text

LRRC34

  • The polygenic nature of telomere length and the anti-ageing properties of lithium. / 03.2019 / PubMed / Full text

LRRC8B

  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

LRRK1

  • Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice. / 15.11.2017 / PubMed / Full text

LTF

  • Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text

LY6D

  • LY6D-induced macropinocytosis as a survival mechanism of senescent cells. / 09.11.2020 / PubMed / Full text

LY86

  • Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. / 09.2019 / PubMed / Full text

LYG1

  • Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text

LYST

  • Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text

MAF

  • Biocatalytic Degradation Efficiency of Postconsumer Polyethylene Terephthalate Packaging Determined by Their Polymer Microstructures. / 17.07.2019 / PubMed / Full text

MAF1

  • Beyond regulation of pol III: Role of MAF1 in growth, metabolism, aging and cancer. / 04.2018 / PubMed / Full text

MAFB

  • Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy. / 01.04.2019 / PubMed / Full text

MAL

  • Daylight photodynamic therapy versus cryosurgery for the treatment and prophylaxis of actinic keratoses of the face - protocol of a multicenter, prospective, randomized, controlled, two-armed study. / 25.10.2017 / PubMed / Full text

MAOA

  • Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. / 05.10.2017 / PubMed / Full text

MAP1A

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

MAP1B

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

MAP2K3

  • Associations of [i]MAP2K3[/i] Gene Variants With Superior Memory in SuperAgers. / 2018 / PubMed / Full text

MAP3K5

  • Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. / 08.10.2018 / PubMed / Full text

MAP4K3

MAPK10

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

MAPK11

  • lncRNA ENSMUST00000134285 Increases MAPK11 Activity, Regulating Aging-Related Myocardial Apoptosis. / 09.07.2018 / PubMed / Full text

MAPK13

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

MAPK8

  • Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

MARCKS

  • Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology. / 07-08.2018 / PubMed / Full text

MARCKSL1

  • MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors. / 04.2018 / PubMed / Full text

MARK1

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

MAS1

  • AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation. / 17.04.2018 / PubMed / Full text

MATN3

  • Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis. / 19.01.2020 / PubMed / Full text

MAVS

  • Spontaneous activation of a MAVS-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes. / 10.2017 / PubMed / Full text

MAX

  • Validation of the MedUseQ: A Self-Administered Screener for Older Adults to Assess Medication Use Problems. / 10.2019 / PubMed / Full text

MBD2

  • Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords. / 02.2019 / PubMed / Full text

MC1R

  • In vitro behavior and UV response of melanocytes derived from carriers of [[CDKN2A]] mutations and MC1R variants. / 03.2019 / PubMed / Full text

MCAT

  • Small molecules as therapeutic drugs for Alzheimer's disease. / 04.2019 / PubMed / Full text

MCF2L

  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

MCM3

MCM4

MCM5

MCM6

MCM8

  • Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. / 2017 / PubMed / Full text

MCM9

  • MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors. / 10.09.2019 / PubMed / Full text

MCUR1

  • Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. / 09.2019 / PubMed / Full text

MDK

  • A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text

MDN1

  • Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text

ME1

  • NADP-MALIC ENZYME 1 Affects Germination after Seed Storage in Arabidopsis thaliana. / 01.02.2019 / PubMed / Full text

MECOM

  • Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease. / 11.2018 / PubMed / Full text

MED25

  • The [i]HAC1[/i] histone acetyltransferase promotes leaf senescence and regulates the expression of [i]ERF022[/i]. / 08.2019 / PubMed / Full text

MEFV

MEOX2

  • Reduced expression of microRNA-130a promotes endothelial cell senescence and age-dependent impairment of neovascularization. / 26.05.2020 / PubMed / Full text

MERTK

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

MEST

  • Improving specific autobiographical memory in older adults: impacts on mood, social problem solving, and functional limitations. / 09.2018 / PubMed / Full text

MFN1

  • Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice. / 2018 / PubMed / Full text

MFSD2A

  • Decreased Blood Level of MFSD2a as a Potential Biomarker of Alzheimer's Disease. / 20.12.2019 / PubMed / Full text

MGRN1

  • Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis. / 06.2019 / PubMed / Full text

MIB1

  • Immunohistochemical detection of senescence markers in human sarcomas. / 02.2020 / PubMed / Full text

MICA

  • Derivation and Validation of a Geriatric-Sensitive Perioperative Cardiac Risk Index. / 16.11.2017 / PubMed / Full text

MICB

  • Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

MICU1

  • Cytosolic and mitochondrial Ca concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation. / 09.2019 / PubMed / Full text

MLH3

  • Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes. / 19.10.2017 / PubMed / Full text

MMP12

  • Macrophage-Restricted Shp2 Tyrosine Phosphatase Acts as a Rheostat for MMP12 through TGF-β Activation in the Prevention of Age-Related Emphysema in Mice. / 01.10.2017 / PubMed / Full text

MMP14

  • Overexpression of microRNA-1470 promotes proliferation and migration, and inhibits senescence of esophageal squamous carcinoma cells. / 12.2017 / PubMed / Full text

MMP7

  • Retinoic acid promotes in vitro follicle activation in the cat ovary by regulating expression of matrix metalloproteinase 9. / 2018 / PubMed / Full text

MORF4L1

  • A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. / 20.06.2019 / PubMed / Full text

MPHOSPH6

  • Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. / 05.03.2020 / PubMed / Full text

MPL

  • Molecular Pathogenesis of Myeloproliferative Neoplasms: Influence of Age and Gender. / 10.2017 / PubMed / Full text

MPST

  • Methionine restriction leads to hyperhomocysteinemia and alters hepatic H S production capacity in Fischer-344 rats. / 12.2018 / PubMed / Full text

MR1

MRO

  • [Effects of different intensities exercise combined with resveratrol on RBP4 in aged obese rats]. / 08.05.2017 / PubMed / Full text

MRPS5

  • Mutant MRPS5 affects mitoribosomal accuracy and confers stress-related behavioral alterations. / 11.2018 / PubMed / Full text

MRTFA

  • Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse. / 01.02.2019 / PubMed / Full text

MS4A1

  • Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text

MS4A4E

  • Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text

MS4A6A

  • Recent studies on cellular and molecular mechanisms in Alzheimer's disease: focus on epigenetic factors and histone deacetylase. / 28.03.2018 / PubMed / Full text

MSH2

  • RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text

MSH3

  • RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text

MSH6

  • RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text

MSRA

  • Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasis. / 02.2019 / PubMed / Full text

MST1

  • [Expression relationship of Hippo signaling molecules and ovarian germline stem cell markers in the ovarian aging process of women and mice]. / 25.06.2019 / PubMed

MTRR

  • One-carbon metabolism gene polymorphisms are associated with cognitive trajectory among African-American adults. / 12.2019 / PubMed / Full text

MUC5AC

  • InflammAging at Ocular Surface: Clinical and Biomolecular Analyses in Healthy Volunteers. / 01.04.2019 / PubMed / Full text

MUC7

  • Reduced Salivary Mucin Binding and Glycosylation in Older Adults Influences Taste in an In Vitro Cell Model. / 24.09.2019 / PubMed / Full text

MUL1

  • Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models. / 28.05.2019 / PubMed / Full text

MUS81

  • Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling. / 2019 / PubMed / Full text

MX1

  • Age-Associated Changes in the Respiratory Epithelial Response to Influenza Infection. / 10.11.2018 / PubMed / Full text

MYCN

  • Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells. / 2020 / PubMed / Full text

MYCNOS

  • Insights into the Function of Long Noncoding RNAs in Sepsis Revealed by Gene Co-Expression Network Analysis. / 26.01.2017 / PubMed / Full text

MYH10

  • Epigenome-wide exploratory study of monozygotic twins suggests differentially methylated regions to associate with hand grip strength. / 10.2019 / PubMed / Full text

MYLPF

  • Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. / 15.05.2019 / PubMed / Full text

MYO1F

  • A Microglial Signature Directing Human Aging and Neurodegeneration-Related Gene Networks. / 2019 / PubMed / Full text

MYOC

  • Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells. / 28.12.2018 / PubMed / Full text

MYOF

  • Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study. / 08.10.2018 / PubMed / Full text

MYSM1

  • MYSM1 Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan. / 11.2020 / PubMed / Full text

MYT1

  • ESC-sEVs Rejuvenate Aging Hippocampal NSCs by Transferring SMADs to Regulate the MYT1-Egln3-Sirt1 Axis. / 01.10.2020 / PubMed / Full text

NACA

  • Age and Sex Are Strongly Correlated to the Rate and Type of Mountain Injuries Requiring Search and Rescue Missions. / 12.2019 / PubMed / Full text

NAIP

  • Protective effect of xanthohumol against age-related brain damage. / 11.2017 / PubMed / Full text

NBN

  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text

NBR1

  • Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner. / 03.2018 / PubMed / Full text

NCK2

  • Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

NCOR2

  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

NDN

  • The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging. / 2018 / PubMed / Full text

NDRG1

  • Cx43 phosphorylation-mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein NDRG1. / 02.08.2019 / PubMed / Full text

NDRG2

  • NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain. / 04.01.2020 / PubMed / Full text

NDUFAB1

  • Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

NDUFS1

  • Mapping the protein phosphorylation sites in human mitochondrial complex I (NADH: Ubiquinone oxidoreductase): A bioinformatics study with implications for brain aging and neurodegeneration. / 01.2019 / PubMed / Full text

NDUFS3

  • Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10). / 06.2018 / PubMed / Full text

NDUFS8

  • Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity. / 01.10.2020 / PubMed / Full text

NDUFV2

  • Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text

NEFM

  • Changes in mechanoreceptors in rabbits' anterior cruciate ligaments with age. / 06.2019 / PubMed / Full text

NEIL1

  • NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress. / 09.2019 / PubMed / Full text

NEIL3

  • Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin. / 2019 / PubMed / Full text

NEK2

  • Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma. / 21.11.2018 / PubMed / Full text

NEO1

  • Neogenin-1 distinguishes between myeloid-biased and balanced [i]Hoxb5[/i] mouse long-term hematopoietic stem cells. / 10.12.2019 / PubMed / Full text

NFATC1

  • Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. / 02.10.2017 / PubMed / Full text

NFKB1

  • NFKB1 gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation. / 03.2020 / PubMed / Full text

NGFR

  • Evidence for changing nerve growth factor signalling mechanisms during development, maturation and ageing in the rat molar pulp. / 02.2019 / PubMed / Full text

NKAP

  • NKAP Regulates Senescence and Cell Death Pathways in Hematopoietic Progenitors. / 2019 / PubMed / Full text

NKIRAS2

  • Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

NKX2-5

  • Isolation, Characterization, and Differentiation of Cardiac Stem Cells from the Adult Mouse Heart. / 07.01.2019 / PubMed / Full text

NKX6-1

  • The dynamic methylome of islets in health and disease. / 09.2019 / PubMed / Full text

NLRC5

  • Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians. / 02.02.2018 / PubMed / Full text

NLRP1

  • NADPH oxidase 2-mediated NLRP1 inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro. / 04.2019 / PubMed / Full text

NLRP12

  • Persistent DNA damage-induced NLRP12 improves hematopoietic stem cell function. / 21.05.2020 / PubMed / Full text

NLRP6

  • LRP6 targeting suppresses gastric tumorigenesis via P14 -Mdm2-P53-dependent cellular senescence. / 19.12.2017 / PubMed / Full text

NLRX1

  • NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells. / 26.02.2018 / PubMed / Full text

NMI

  • Age-Dependent Control of Shoulder Muscles During a Reach-and-Lift Task. / 10.12.2019 / PubMed / Full text

NMRK2

  • Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training. / 2018 / PubMed / Full text

NMS

  • Uncontrolled Diabetes as an Associated Factor with Dynapenia in Adults Aged 50 Years or Older: Sex Differences. / 22.05.2020 / PubMed / Full text

NMUR1

  • [Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules]. / 2019 / PubMed / Full text

NOA1

  • The dependence of leaf senescence on the balance between 1-aminocyclopropane-1-carboxylate acid synthase 1 (ACS1)-catalysed ACC generation and nitric oxide-associated 1 (NOS1)-dependent NO accumulation in Arabidopsis. / 07.2019 / PubMed / Full text

NOBOX

  • Observation of the influences of diosgenin on aging ovarian reserve and function in a mouse model. / 18.10.2017 / PubMed / Full text

NOL12

  • NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging. / 15.06.2019 / PubMed / Full text

NOTCH4

  • Age-dependent autophagy induction after injury promotes axon regeneration by limiting NOTCH. / 11.2020 / PubMed / Full text

NPAS2

  • Is the aging human ovary still ticking?: Expression of clock-genes in luteinized granulosa cells of young and older women. / 21.11.2018 / PubMed / Full text

NPBWR1

  • Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

NPC2

  • Attenuation of the Niemann-Pick type C2 disease phenotype by intracisternal administration of an AAVrh.10 vector expressing Npc2. / 08.2018 / PubMed / Full text

NPM1

  • Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats. / 29.11.2019 / PubMed / Full text

NPRL2

  • KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text

NPRL3

  • KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing. / 05.2018 / PubMed / Full text

NPW

  • Novel information processing at work across time is associated with cognitive change in later life: A 14-year longitudinal study. / 09.2020 / PubMed / Full text

NR3C1

  • Glucocorticoid receptor (NR3C1) gene polymorphisms are associated with age and blood parameters in Polish Caucasian nonagenarians and centenarians. / 02.2019 / PubMed / Full text

NRARP

  • Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing NRARP. / 10.11.2018 / PubMed / Full text

NRL

  • Development of a cyclophosphamide stress test to predict resilience to aging in mice. / 12.2020 / PubMed / Full text

NRM

  • Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation. / 12.2019 / PubMed / Full text

NRXN3

  • Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text

NSF

  • Effects of air pollution on children from a socioecological perspective. / 15.11.2019 / PubMed / Full text

NT5E

  • The NT5E gene variant strongly affects the degradation rate of inosine 5'-monophosphate under postmortem conditions in Japanese Black beef. / 12.2019 / PubMed / Full text

NTHL1

  • Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals. / 04.2020 / PubMed / Full text

NTN4

  • EGF/EGFR upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence. / 04.12.2018 / PubMed / Full text

NUCB2

  • Ontogenetic Pattern Changes of Nucleobindin-2/Nesfatin-1 in the Brain and Intestinal Bulb of the Short Lived African Turquoise Killifish. / 31.12.2019 / PubMed / Full text

NUPR1

OCLN

  • Reduction of Aging-Induced Oxidative Stress and Activation of Autophagy by Bilberry Anthocyanin Supplementation via the AMPK-mTOR Signaling Pathway in Aged Female Rats. / 17.07.2019 / PubMed / Full text

OGA

  • NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase. / 19.11.2019 / PubMed / Full text

OLFML3

  • Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text

OMD

  • Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages. / 06.02.2019 / PubMed / Full text

OOEP

  • Maternal gene [i]Ooep[/i] may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes. / 18.11.2018 / PubMed / Full text

OSGEP

  • Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text

OSM

  • Age Differences in Sexual Minority Stress and the Importance of Friendship in Later Life. / 04.11.2020 / PubMed / Full text

OTX2

  • Tau Deficiency Down-Regulated Transcription Factor Orthodenticle Homeobox 2 Expression in the Dopaminergic Neurons in Ventral Tegmental Area and Caused No Obvious Motor Deficits in Mice. / 01.03.2018 / PubMed / Full text

OXR1

  • Oxidation resistance 1 is a novel senolytic target. / 08.2018 / PubMed / Full text

P2RY10

  • Divergent age-dependent peripheral immune transcriptomic profile following traumatic brain injury. / 12.06.2019 / PubMed / Full text

P4HA2

  • Expanding the Phenotypic and Genotypic Landscape of Nonsyndromic High Myopia: A Cross-Sectional Study in 731 Chinese Patients. / 03.09.2019 / PubMed / Full text

P4HA3

  • Age-associated genes in human mammary gland drive human breast cancer progression. / 15.06.2020 / PubMed / Full text

PABPN1

  • Dysfunctional transcripts are formed by alternative polyadenylation in OPMD. / 26.09.2017 / PubMed / Full text

PAFAH2

  • Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs. / 03.2019 / PubMed / Full text

PARK7

  • The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text

PAX1

  • Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence. / 26.06.2018 / PubMed / Full text

PAX5

  • Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low PAX5. / 08.2018 / PubMed / Full text

PAX7

  • Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits. / 10.2018 / PubMed / Full text

PAX8

  • Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging. / 13.09.2019 / PubMed / Full text

PBX1

  • Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence. / 10.2020 / PubMed / Full text

PCCA

  • Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism. / 03.2018 / PubMed / Full text

PCCB

  • Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism. / 03.2018 / PubMed / Full text

PCDHGA3

  • DNA methylation associated with healthy aging of elderly twins. / 12.2018 / PubMed / Full text

PCMTD1

  • Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

PDE10A

  • Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain. / 01.2018 / PubMed / Full text

PDE2A

  • TAK-915, a phosphodiesterase 2A inhibitor, ameliorates the cognitive impairment associated with aging in rodent models. / 30.12.2019 / PubMed / Full text

PDE4B

  • Phosphodiesterase-4B as a Therapeutic Target for Cognitive Impairment and Obesity-Related Metabolic Diseases. / 2017 / PubMed / Full text

PDE4C

  • Effect of adding B-vitamins to vitamin D and calcium supplementation on CpG methylation of epigenetic aging markers. / 04.2018 / PubMed / Full text

PDE5A

  • Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass. / 23.06.2020 / PubMed / Full text

PDE9A

  • Identification of new PDE9A isoforms and how their expression and subcellular compartmentalization in the brain change across the life span. / 05.2018 / PubMed / Full text

PDF

  • Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models. / 28.05.2019 / PubMed / Full text

PDGFRB

  • A tyrosine kinase-activating variant Asn666Ser in PDGFRB causes a progeria-like condition in the severe end of Penttinen syndrome. / 04.2019 / PubMed / Full text

PDHB

  • Neuron-specific knockdown of Drosophila PDHB induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting. / 15.05.2018 / PubMed / Full text

PDK4

  • Putrescine delays postovulatory aging of mouse oocytes by upregulating PDK4 expression and improving mitochondrial activity. / 16.12.2018 / PubMed / Full text

PEBP1

  • [i]Drosophila[/i] PEBP1 inhibits intestinal stem cell aging via suppression of ERK pathway. / 06.04.2018 / PubMed / Full text

PER3

  • Effects of PER3 clock gene polymorphisms on aging-related changes of the cerebral cortex. / 03.2018 / PubMed / Full text

PES1

  • Transcription factor RD26 is a key regulator of metabolic reprogramming during dark-induced senescence. / 06.2018 / PubMed / Full text

PEX19

  • A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells. / 02.2020 / PubMed / Full text

PEX5

  • Aging lowers PEX5 levels in cortical neurons in male and female mouse brains. / 09.2020 / PubMed / Full text

PF4V1

  • Involvement of ERK1/2 activation in the gene expression of senescence-associated secretory factors in human hepatic stellate cells. / 05.2019 / PubMed / Full text

PFKFB3

  • DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system. / 05.2018 / PubMed / Full text

PGAP1

  • Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues. / 07.2018 / PubMed / Full text

PGK2

  • Arsenic influences spermatogenesis by disorganizing the elongation of spermatids in adult male mice. / 01.2020 / PubMed / Full text

PGLS

  • 547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates. / 28.11.2019 / PubMed / Full text

PGM1

  • Explaining meat quality of bulls and steers by differential proteome and phosphoproteome analysis of skeletal muscle. / 15.05.2019 / PubMed / Full text

PHB

  • Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation. / 02.2019 / PubMed / Full text

PHB2

  • Prohibitin-2 is a novel regulator of p21 induced by depletion of γ-glutamylcyclotransferase. / 29.01.2018 / PubMed / Full text

PHGDH

  • Tanshinone prevents alveolar bone loss in ovariectomized osteoporosis rats by up-regulating phosphoglycerate dehydrogenase. / 01.08.2019 / PubMed / Full text

PIGR

  • Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

PIK3C2A

  • Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text

PIK3R1

  • Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity. / 08.10.2018 / PubMed / Full text

PIK3R2

  • The senescent status of endothelial cells affects proliferation, inflammatory profile and SOX2 expression in bone marrow-derived mesenchymal stem cells. / 06.2019 / PubMed / Full text

PIM1

  • PIM1-catalyzed CBX8 phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast. / 27.06.2018 / PubMed / Full text

PIP5K1C

  • [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text

PKD1

  • The protein kinase D1-mediated classical protein secretory pathway regulates the Ras oncogene-induced senescence response. / 16.03.2018 / PubMed / Full text

PLA2G6

  • Mutations in the Drosophila homolog of human PLA2G6 give rise to age-dependent loss of psychomotor activity and neurodegeneration. / 13.02.2018 / PubMed / Full text

PLA2R1

  • Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes. / 12.2018 / PubMed / Full text

PLCG2

  • A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity. / 08.2019 / PubMed / Full text

PLD3

  • Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text

PLK1

  • Dynactin pathway-related gene expression is altered by aging, but not by vitrification. / 09.2019 / PubMed / Full text

PLN

  • An analysis of the costs of treating aged patients in a large clinical hospital in Poland under the pressure of recent demographic trends. / 2020 / PubMed / Full text

PLXNA4

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

PMP22

  • Role of microRNAs in senescence and its contribution to peripheral neuropathy in the arsenic exposed population of West Bengal, India. / 02.2018 / PubMed / Full text

PMS1

  • RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text

PMS2

  • RNA-Seq analysis of differentially expressed genes relevant to mismatch repair in aging hematopoietic stem-progenitor cells. / 25.02.2019 / PubMed / Full text

POLG2

  • An N-Ethyl-N-Nitrosourea (ENU)-Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice. / 03.2019 / PubMed / Full text

POLL

  • Temporal trends in loss of life expectancy after a cancer diagnosis among the Australian population. / 04.2020 / PubMed / Full text

POLR3A

  • Nucleolar disruption, activation of P53 and premature senescence in POLR3A-mutated Wiedemann-Rautenstrauch syndrome fibroblasts. / 12.2020 / PubMed / Full text

PON1

  • Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview. / 02.05.2019 / PubMed / Full text

POU3F2

  • POU3F2 participates in cognitive function and adult hippocampal neurogenesis via mammalian-characteristic amino acid repeats. / 02.2018 / PubMed / Full text

POU5F1

  • Cell quality evaluation with gene expression analysis of spheroids (3D) and adherent (2D) adipose stem cells. / 24.10.2020 / PubMed / Full text

PPA2

  • Characterization of long living yeast deletion mutants that lack mitochondrial metabolism genes DSS1, PPA2 and AFG3. / 20.07.2019 / PubMed / Full text

PPARG

  • The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity. / 04-06.2018 / PubMed / Full text

PPARGC1A

  • Maternal ageing impairs mitochondrial DNA kinetics during early embryogenesis in mice. / 08.07.2019 / PubMed / Full text

PPFIA1

  • Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text

PPM1A

  • The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1. / 03.08.2019 / PubMed / Full text

PPP1R3C

  • Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text

PPP2R1A

  • Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text

PPP2R3C

  • The mir-465 family is upregulated with age and attenuates growth hormone signaling in mouse liver. / 04.2019 / PubMed / Full text

PPP3CB

  • Gene Expression Analysis Reveals Novel Gene Signatures Between Young and Old Adults in Human Prefrontal Cortex. / 2018 / PubMed / Full text

PRDM1

  • Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients. / 17.01.2019 / PubMed / Full text

PRDM16

  • Assessment of the Aging of the Brown Adipose Tissue by F-FDG PET/CT Imaging in the Progeria Mouse Model Lmna . / 2018 / PubMed / Full text

PRDM8

  • PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation. / 20.08.2020 / PubMed / Full text

PRDX6

  • Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task. / 2019 / PubMed / Full text

PREP

  • Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

PRG4

  • Inhibition of Wnt/β-catenin signaling ameliorates osteoarthritis in a murine model of experimental osteoarthritis. / 08.02.2018 / PubMed / Full text

PRKAA1

  • Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

PRKCB

  • MEF2A alters the proliferation, inflammation-related gene expression profiles and its silencing induces cellular senescence in human coronary endothelial cells. / 18.03.2019 / PubMed / Full text

PRKCH

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

PRKDC

  • DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis. / 29.08.2019 / PubMed / Full text

PRKG1

  • Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis. / 15.07.2018 / PubMed / Full text

PRKN

  • PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. / 03.2019 / PubMed / Full text

PRLR

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

PRM1

  • Cytological and molecular aspects of the ageing sperm. / 01.02.2019 / PubMed / Full text

PRM2

  • Cytological and molecular aspects of the ageing sperm. / 01.02.2019 / PubMed / Full text

PRMT1

  • Reactive oxygen species extend insect life span using components of the insulin-signaling pathway. / 12.09.2017 / PubMed / Full text

PRMT8

  • Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons. / 29.08.2018 / PubMed / Full text

PRNP

  • Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS. / 06.2020 / PubMed / Full text

PRR9

  • Circadian control of [i]ORE1[/i] by PRR9 positively regulates leaf senescence in [i]Arabidopsis[/i]. / 14.08.2018 / PubMed / Full text

PRRX1

  • A SIRT1-centered circuitry regulates breast cancer stemness and metastasis. / 12.2018 / PubMed / Full text

PSAP

  • Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. / 08.2018 / PubMed / Full text

PSMB8

  • [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text

PSMD11

  • The effect and mechanism of 19S proteasome PSMD11/Rpn6 subunit in D-Galactose induced mimetic aging models. / 01.09.2020 / PubMed / Full text

PSMD13

  • Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

PSMD14

  • Upregulation of deubiquitinase PSMD14 in lung adenocarcinoma (LUAD) and its prognostic significance. / 2020 / PubMed / Full text

PSMG1

  • Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. / 03.2018 / PubMed / Full text

PTCH1

  • Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text

PTGS2

  • Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism. / 21.05.2019 / PubMed / Full text

PTK2B

  • Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. / 11.2018 / PubMed / Full text

PTK7

  • Innate and adaptive immune dysregulation in critically ill ICU patients. / 05.07.2018 / PubMed / Full text

PTN

  • Connecting Metainflammation and Neuroinflammation Through the PTN-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development. / 2019 / PubMed / Full text

PTP4A3

  • Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease. / 05.2020 / PubMed / Full text

PTPN1

  • The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text

PTPRC

  • Selective molecular biomarkers to predict biologic behavior in pituitary tumors. / 05.2017 / PubMed / Full text

PTPRD

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

PTPRR

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

PTTG1

  • [Down-regulated PTTG1 expression promotes the senescence of human prostate cancer LNCaP-AI]. / 03.2019 / PubMed

PUM1

  • Identification of reference genes for RT-qPCR data normalisation in aging studies. / 27.09.2019 / PubMed / Full text

PYCR1

  • A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals POSTN As a New Element in Proline Metabolic Disorder. / 12.2018 / PubMed / Full text

QRFPR

  • Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text

RAB1B

  • Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

RACK1

  • Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging. / 05.11.2019 / PubMed / Full text

RAD23A

  • Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

RAD50

  • Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells. / 01.09.2018 / PubMed / Full text

RAD51B

  • Increased age-adjusted hazard of death associated with a common single nucleotide polymorphism of the human RAD52 gene in a cardiovascular cohort. / 10.2017 / PubMed / Full text

RAD51C

  • Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population. / 06.2019 / PubMed / Full text

RAD9A

  • Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

RAF1

  • Circular [i]ANRIL[/i] isoforms switch from repressors to activators of [i]p15/CDKN2B[/i] expression during RAF1 oncogene-induced senescence. / 29.09.2020 / PubMed / Full text

RAG2

  • Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation. / 2020 / PubMed / Full text

RAI1

  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

RARB

  • Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. / 12.2019 / PubMed / Full text

RB1

  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text

RBM25

  • HPV shapes tumor transcriptome by globally modifying the pool of RNA binding protein-binding motif. / 29.04.2019 / PubMed / Full text

RBM3

  • Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain. / 2018 / PubMed / Full text

RBM38

  • Genetic Ablation of [i]Rbm38[/i] Promotes Lymphomagenesis in the Context of Mutant p53 by Downregulating PTEN. / 15.03.2018 / PubMed / Full text

RBMXL1

  • Whole-Exome Sequencing of an Exceptional Longevity Cohort. / 16.08.2019 / PubMed / Full text

RBP1

  • The SR proteins SF2 and RBP1 regulate triglyceride storage in the fat body of Drosophila. / 27.08.2019 / PubMed / Full text

RBP4

  • [Effects of different intensities exercise combined with resveratrol on RBP4 in aged obese rats]. / 08.05.2017 / PubMed / Full text

RCAN1

  • Mitochondrial dysfunction and endoplasmic reticulum stress involved in oocyte aging: an analysis using single-cell RNA-sequencing of mouse oocytes. / 08.06.2019 / PubMed / Full text

REC8

  • Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice. / 10.2018 / PubMed / Full text

RELA

  • Genome-wide association study and annotating candidate gene networks affecting age at first calving in Nellore cattle. / 12.2017 / PubMed / Full text

RELB

  • New control of the senescence barrier in breast cancer. / 2020 / PubMed / Full text

REV1

  • REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks. / 17.11.2020 / PubMed / Full text

RGS14

  • Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. / 08.2018 / PubMed / Full text

RGS2

  • Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone. / 01.05.2019 / PubMed / Full text

RHCG

  • Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma. / 06.06.2019 / PubMed / Full text

RHEBL1

  • Long-lived rodents reveal signatures of positive selection in genes associated with lifespan. / 03.2018 / PubMed / Full text

RHOB

  • Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes. / 13.06.2019 / PubMed / Full text

RICTOR

  • Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. / 11.2019 / PubMed / Full text

RIF1

  • 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. / 02.01.2020 / PubMed / Full text

RIMS2

  • Age-related gene and miRNA expression changes in airways of healthy individuals. / 06.03.2019 / PubMed / Full text

RIPK2

  • RIP kinases as modulators of inflammation and immunity. / 09.2018 / PubMed / Full text

RNF10

  • Reduced RING finger protein 10 expression in macrophages is associated with aging-related inflammation. / 28.11.2020 / PubMed / Full text

RNF13

  • The effects of environmental stressors on candidate aging associated genes. / 08.2020 / PubMed / Full text

RNF144A

  • Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. / 09.2019 / PubMed / Full text

RNF168

  • PML nuclear bodies are recruited to persistent DNA damage lesions in an RNF168-53BP1 dependent manner and contribute to DNA repair. / 06.2019 / PubMed / Full text

RORA

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

ROS1

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

RPA2

  • Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

RPE65

  • Effects of Ranibizumab, Bevacizumab, and Aflibercept on Senescent Retinal Pigment Epithelial Cells. / 08.2018 / PubMed / Full text

RPIA

  • Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming. / 20.08.2019 / PubMed / Full text

RPL11

  • NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging. / 15.06.2019 / PubMed / Full text

RPL13

  • Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text

RPL30

  • Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text

RPL31

  • Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text

RPL36

  • Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

RPL37

  • Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text

RPL4

  • Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

RPS19BP1

  • Material basis, effect, and mechanism of ethanol extract of Pinellia ternata tubers on oxidative stress-induced cell senescence. / 10.2020 / PubMed / Full text

RPS6KB1

  • Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text

RPTOR

  • Endothelial replicative senescence delayed by the inhibition of MTORC1 signaling involves MicroRNA-107. / 08.2018 / PubMed / Full text

RRAD

  • Pan-senescence transcriptome analysis identified RRAD as a marker and negative regulator of cellular senescence. / 01.2019 / PubMed / Full text

RRM1

  • α-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1. / 08.2019 / PubMed / Full text

RRM2B

  • Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs. / 15.07.2018 / PubMed / Full text

RSF1

  • The SR proteins SF2 and RBP1 regulate triglyceride storage in the fat body of Drosophila. / 27.08.2019 / PubMed / Full text

RTN4

  • Cell fate regulation by reticulon-4 in human prostate cancers. / 07.2019 / PubMed / Full text

RUNX3

  • circLARP4 induces cellular senescence through regulating miR-761/RUNX3/p53/p21 signaling in hepatocellular carcinoma. / 02.2019 / PubMed / Full text

RXFP3

  • The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage. / 03.12.2019 / PubMed / Full text

RXRA

  • The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling. / 12.2018 / PubMed / Full text

RXRG

  • Genetic variations, reproductive aging, and breast cancer risk in African American and European American women: The Women's Circle of Health Study. / 2017 / PubMed / Full text

S100A12

  • Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model. / 06.07.2018 / PubMed / Full text

S100A13

  • S100A13 promotes senescence-associated secretory phenotype and cellular senescence via modulation of non-classical secretion of IL-1α. / 23.01.2019 / PubMed / Full text

S100A6

  • Sex differences in distribution of cannabinoid receptors (CB1 and CB2), S100A6 and CacyBP/SIP in human ageing hearts. / 27.11.2018 / PubMed / Full text

S1PR3

  • Sexual dimorphism of metabolic and vascular dysfunction in aged mice and those lacking the sphingosine 1-phosphate receptor 3. / 01.12.2017 / PubMed / Full text

SAA2

  • Naturally occurring antibodies against serum amyloid A reduce IL-6 release from peripheral blood mononuclear cells. / 2018 / PubMed / Full text

SALL1

  • SALL1 functions as a tumor suppressor in breast cancer by regulating cancer cell senescence and metastasis through the NuRD complex. / 06.04.2018 / PubMed / Full text

SAMD10

  • Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression. / 11.2017 / PubMed / Full text

SAMD12

  • Genome-wide scan of depressive symptomatology in two representative cohorts in the United States and the United Kingdom. / 05.2018 / PubMed / Full text

SARM1

  • Sarm1 Deletion, but Not Wld , Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy. / 03.10.2017 / PubMed / Full text

SAT1

  • Triethylenetetramine (trientine): a caloric restriction mimetic with a new mode of action. / 08.2020 / PubMed / Full text

SATB2

  • microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia. / 06.2019 / PubMed / Full text

SCAMP4

SCGN

  • Detection and evaluation of DNA methylation markers found at SCGN and KLF14 loci to estimate human age. / 11.2017 / PubMed / Full text

SCN2A

  • Na 1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age. / 09.09.2019 / PubMed / Full text

SCN2B

  • MicroRNA‑449a regulates the progression of brain aging by targeting SCN2B in SAMP8 mice. / 04.2020 / PubMed / Full text

SCN5A

  • [Use of Pharmacogenetic Information for Therapeutic Drug Monitoring of an Antiarrhythmic Drug]. / 2018 / PubMed / Full text

SCN9A

  • The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway. / 06.2018 / PubMed / Full text

SCNN1B

  • Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. / 18.10.2018 / PubMed / Full text

SCO1

  • Real-Time PCR Analysis of Metabolism-Related Genes in a Long-Lived Model of C. elegans. / 2020 / PubMed / Full text

SCX

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

SDC2

  • Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. / 01.10.2017 / PubMed / Full text

SDC3

  • Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. / 01.10.2017 / PubMed / Full text

SDC4

  • Alterations in Corneal Sensory Nerves During Homeostasis, Aging, and After Injury in Mice Lacking the Heparan Sulfate Proteoglycan Syndecan-1. / 01.10.2017 / PubMed / Full text

SDHB

  • Mitochondrial Signatures in Circulating Extracellular Vesicles of Older Adults with Parkinson's Disease: Results from the EXosomes in PArkiNson's Disease (EXPAND) Study. / 12.02.2020 / PubMed / Full text

SELENBP1

  • A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity. / 01.2020 / PubMed / Full text

SELENOH

  • The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text

SELENOK

  • Dietary selenium deficiency and supplementation differentially modulate the expression of two ER-resident selenoproteins (selenoprotein K and selenoprotein M) in the ovaries of aged mice: Preliminary data. / 09.2020 / PubMed / Full text

SELENOP

  • Analyses of Selenotranscriptomes and Selenium Concentrations in Response to Dietary Selenium Deficiency and Age Reveal Common and Distinct Patterns by Tissue and Sex in Telomere-Dysfunctional Mice. / 10.2017 / PubMed / Full text

SELENOT

  • The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text

SELENOV

  • The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text

SELENOW

  • The Thioredoxin-Like Family of Selenoproteins: Implications in Aging and Age-Related Degeneration. / 03.2019 / PubMed / Full text

SEMA3A

  • Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging. / 05.03.2019 / PubMed / Full text

SEMA6C

  • Suppression of SEMA6C promotes preantral follicles atresia with decreased cell junctions in mice ovaries. / 04.2019 / PubMed / Full text

SENP1

  • Aging-related SUMOylation pattern in the cortex and blood plasma of wild type mice. / 06.03.2018 / PubMed / Full text

SENP6

  • Molecular signature for senile and complicated cataracts derived from analysis of sumoylation enzymes and their substrates in human cataract lenses. / 10.2020 / PubMed / Full text

SERPINA1

  • Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

SERPINB2

  • An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through SERPINB2. / 03.07.2019 / PubMed / Full text

SESN1

  • Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis. / 09.2018 / PubMed / Full text

SESN3

SF1

  • Prepubertal exposure to perfluorononanoic acid interferes with spermatogenesis and steroidogenesis in male mice. / 15.04.2019 / PubMed / Full text

SFPQ

  • Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis. / 08.04.2020 / PubMed / Full text

SFRP1

  • [Role and alterations of DNA methylation during the aging and cancer]. / 01.2018 / PubMed / Full text

SFRP2

  • [Role and alterations of DNA methylation during the aging and cancer]. / 01.2018 / PubMed / Full text

SFRP5

  • SFRP5 serves a beneficial role in arterial aging by inhibiting the proliferation, migration and inflammation of smooth muscle cells. / 11.2018 / PubMed / Full text

SGK1

  • Epigenetic Regulation of KL (Klotho) via H3K27me3 (Histone 3 Lysine [K] 27 Trimethylation) in Renal Tubule Cells. / 05.2020 / PubMed / Full text

SGSH

  • MPS-IIIA mice acquire autistic behaviours with age. / 07.2018 / PubMed / Full text

SH2B3

  • Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. / 13.10.2017 / PubMed / Full text

SHANK3

  • Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background. / 10.10.2018 / PubMed / Full text

SHD

  • Does self-reported hearing difficulty decrease older adults' cognitive and physical functioning? The mediating role of social isolation. / 11.2020 / PubMed / Full text

SIK3

  • Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids. / 25.09.2020 / PubMed / Full text

SIL1

  • SIL1, the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology. / 10.05.2018 / PubMed / Full text

SIX3

  • CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type. / 30.11.2018 / PubMed / Full text

SKAP2

  • Longevity-related molecular pathways are subject to midlife "switch" in humans. / 08.2019 / PubMed / Full text

SKI

  • Preventive effect of Shenkang injection against high glucose-induced senescence of renal tubular cells. / 04.2019 / PubMed / Full text

SLC15A1

  • Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing. / 02.2019 / PubMed / Full text

SLC15A2

  • Molecular changes to the rat renal cotransporters PEPT1 and PEPT2 due to ageing. / 02.2019 / PubMed / Full text

SLC16A7

  • Genetics of facial telangiectasia in the Rotterdam Study: a genome-wide association study and candidate gene approach. / 23.10.2020 / PubMed / Full text

SLC19A1

  • Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer. / 30.03.2018 / PubMed / Full text

SLC1A5

  • SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice. / 06.2019 / PubMed / Full text

SLC22A14

  • Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort. / 01.2018 / PubMed / Full text

SLC22A23

  • Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease. / 11.2018 / PubMed / Full text

SLC24A5

SLC26A2

  • Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis. / 01.2020 / PubMed / Full text

SLC2A4

  • Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

SLC30A1

  • Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text

SLC30A10

  • Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text

SLC30A5

  • Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text

SLC39A6

  • Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence. / 01.12.2017 / PubMed / Full text

SLC41A1

  • Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis. / 08.05.2019 / PubMed / Full text

SLC52A2

  • Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. / 01.11.2017 / PubMed / Full text

SLC52A3

  • Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. / 01.11.2017 / PubMed / Full text

SLC7A11

  • SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes. / 28.10.2017 / PubMed / Full text

SMAD1

  • TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands. / 26.11.2019 / PubMed / Full text

SMARCA5

  • The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability. / 13.07.2018 / PubMed / Full text

SMARCB1

  • High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer. / 17.10.2017 / PubMed / Full text

SMARCD1

  • Delphinidin-3-glucoside suppresses lipid accumulation in HepG2 cells. / 12.2018 / PubMed / Full text

SMC2

  • The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence. / 10.11.2018 / PubMed / Full text

SMC3

  • Effects of Heyan Kuntai Capsule () on Follicular Development and Oocyte Cohesin Levels in Aged Mice. / 10.2018 / PubMed / Full text

SMC4

  • The proteomic study of serially passaged human skin fibroblast cells uncovers down-regulation of the chromosome condensin complex proteins involved in replicative senescence. / 10.11.2018 / PubMed / Full text

SMN1

  • Changing respiratory expectations with the new disease trajectory of nusinersen treated spinal muscular atrophy [SMA] type 1. / 09.2018 / PubMed / Full text

SMN2

  • Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment. / 01.11.2019 / PubMed / Full text

SMO

  • Sonic hedgehog regulation of cavernous nerve regeneration and neurite formation in aged pelvic plexus. / 02.2019 / PubMed / Full text

SMOX

  • Skeletal Muscle Pathophysiology: The Emerging Role of Spermine Oxidase and Spermidine. / 14.02.2018 / PubMed / Full text

SMPD1

  • Alterations in Lipid Profile of the Aging Kidney Identified by MALDI Imaging Mass Spectrometry. / 05.07.2019 / PubMed / Full text

SMYD2

  • Collaboration of MYC and RUNX2 in lymphoma simulates T-cell receptor signaling and attenuates p53 pathway activity. / 10.2019 / PubMed / Full text

SNAI2

  • Reawakening of dormant estrogen-dependent human breast cancer cells by bone marrow stroma secretory senescence. / 17.08.2018 / PubMed / Full text

SND1

  • [Downregulation of SND1 Expression Accelerates Cell Senescence of Human Diploid Fibroblasts 2BS via Modulating the SASP]. / 05.2020 / PubMed / Full text

SOS1

  • Fucoidan⁻Fucoxanthin Ameliorated Cardiac Function via IRS1/GRB2/ SOS1, GSK3β/CREB Pathways and Metabolic Pathways in Senescent Mice. / 21.01.2019 / PubMed / Full text

SOX11

  • A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress. / 10.08.2017 / PubMed / Full text

SOX13

  • In silico analysis of human renin gene-gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases. / 12.2019 / PubMed / Full text

SOX4

  • Age-induced accumulation of methylmalonic acid promotes tumour progression. / 09.2020 / PubMed / Full text

SP1

  • Identification of key genes and transcription factors in aging mesenchymal stem cells by DNA microarray data. / 15.04.2019 / PubMed / Full text

SP2

  • Influence of season, age and management on scrotal thermal profile in Murrah bulls using scrotal infrared digital thermography. / 12.2017 / PubMed / Full text

SP7

  • microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia. / 06.2019 / PubMed / Full text

SPATS2L

  • Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype. / 02.2019 / PubMed / Full text

SPG7

  • Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration. / 21.02.2018 / PubMed / Full text

SPHK1

  • Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina. / 10.2019 / PubMed / Full text

SPHK2

  • Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. / 04.2019 / PubMed / Full text

SPON1

  • APOE influences working memory in non-demented elderly through an interaction with SPON1 rs2618516. / 07.2018 / PubMed / Full text

SPP1

  • Dehydroepiandrosterone enhances decidualization in women of advanced reproductive age. / 04.2018 / PubMed / Full text

SPRTN

  • Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging. / 03.09.2020 / PubMed / Full text

SRD5A2

  • Extract of Plumbago zeylanica enhances the growth of hair follicle dermal papilla cells with down-regulation of 5α-reductase type II. / 11.2020 / PubMed / Full text

SRI

  • The Role of Aging, Drug Dependence, and Hepatitis C Comorbidity in Alcoholism Cortical Compromise. / 01.05.2018 / PubMed / Full text

SRL

  • Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment. / 04-06.2020 / PubMed / Full text

SRM

  • [Geriatric specificities of localized renal cell carcinoma]. / 11.2019 / PubMed / Full text

SRPK1

  • [Age-related changes in the content of serine-arginine protein kinase 1 (SRPK1) in human dermis.] / 2017 / PubMed

SRSF1

  • Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome. / 09.2018 / PubMed / Full text

SRSF3

  • Alternative polyadenylation dependent function of splicing factor SRSF3 contributes to cellular senescence. / 04.03.2019 / PubMed / Full text

SRY

  • Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics. / 26.12.2017 / PubMed / Full text

SSBP2

  • Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

ST18

  • [Target protein candidates of hypothalamus in aging rats with intervention by Qiongyugao]. / 04.2016 / PubMed / Full text

ST6GAL1

STC1

  • Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

STC2

  • Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2. / 05.12.2019 / PubMed / Full text

STK3

  • Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence. / 11.12.2018 / PubMed / Full text

STK32C

  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

STN1

STOML2

  • Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease. / 2017 / PubMed / Full text

STX17

  • Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and XIAP. / 01.10.2019 / PubMed / Full text

SUCNR1

  • [The effect of Mexidol on cerebral mitochondriogenesis at a young age and during aging]. / 2020 / PubMed / Full text

SUGCT

  • Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype. / 09.2020 / PubMed / Full text

SUMO1

  • SUMO1-conjugation is altered during normal aging but not by increased amyloid burden. / 08.2018 / PubMed / Full text

SUN1

  • Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging. / 26.02.2019 / PubMed / Full text

SUN2

  • Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging. / 26.02.2019 / PubMed / Full text

SURF1

  • Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice. / 08.2018 / PubMed / Full text

SUZ12

  • Epigallocatechin-3-gallate and BIX-01294 have different impact on epigenetics and senescence modulation in acute and chronic myeloid leukemia cells. / 05.11.2018 / PubMed / Full text

SV2B

  • Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. / 10.2018 / PubMed / Full text

SV2C

  • Mutant Huntingtin Causes a Selective Decrease in the Expression of Synaptic Vesicle Protein 2C. / 10.2018 / PubMed / Full text

SYNE1

  • Nesprin-1 impact on tumorigenic cell phenotypes. / 02.2020 / PubMed / Full text

SYNJ1

  • Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer's Disease. / 05.06.2018 / PubMed / Full text

SYNJ2

  • DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex. / 25.07.2018 / PubMed / Full text

SYP

  • The neuropeptide-12 improves recognition memory and neuronal plasticity of the limbic system in old rats. / 08.2018 / PubMed / Full text

SYT1

  • Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins. / 2018 / PubMed / Full text

SYT7

  • Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells. / 28.02.2019 / PubMed / Full text

TAAR1

  • Minimal Age-Related Alterations in Behavioral and Hematological Parameters in Trace Amine-Associated Receptor 1 (TAAR1) Knockout Mice. / 03.2020 / PubMed / Full text

TAF7

  • Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. / 22.01.2020 / PubMed / Full text

TAF7L

  • Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. / 22.01.2020 / PubMed / Full text

TARDBP

  • Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice. / 06.2018 / PubMed / Full text

TAS1R2

  • Bitter, Sweet, Salty, Sour and Umami Taste Perception Decreases with Age: Sex-Specific Analysis, Modulation by Genetic Variants and Taste-Preference Associations in 18 to 80 Year-Old Subjects. / 18.10.2018 / PubMed / Full text

TBC1D1

  • Therapeutic and preventive effects of exercise on cardiometabolic parameters in aging and obese rats. / 02.2019 / PubMed / Full text

TCERG1

  • The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity. / 17.07.2019 / PubMed / Full text

TCF15

TCF21

  • Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3. / 22.06.2018 / PubMed / Full text

TCF7

  • Osteoprotection Through the Deletion of the Transcription Factor Rorβ in Mice. / 04.2018 / PubMed / Full text

TCTA

  • Exciplex-Forming Cohost for High Efficiency and High Stability Phosphorescent Organic Light-Emitting Diodes. / 17.01.2018 / PubMed / Full text

TDG

  • lncRNA H19 contributes to oxidative damage repair in the early age-related cataract by regulating miR-29a/TDG axis. / 09.2019 / PubMed / Full text

TDP1

  • UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis. / 12.06.2018 / PubMed / Full text

TECPR2

  • Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging. / 01-03.2019 / PubMed / Full text

TEF

  • Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response. / 10.2020 / PubMed / Full text

TEP1

  • [Influence of Age on the Susceptibility of Anopheles stephensi to Plasmodium berghei Infection]. / 12.2016 / PubMed

TES

  • The Effects of Electrical Stimulation Pulse Duration on Lingual Palatal Pressure Measures During Swallowing in Healthy Older Adults. / 08.2019 / PubMed / Full text

TET3

  • Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords. / 02.2019 / PubMed / Full text

TFPI

  • Identification of cardiovascular health gene variants related to longevity in a Chinese population. / 07.09.2020 / PubMed / Full text

TGDS

  • The evaluation and design of a short depression screening tool in Turkish older adults. / 10.2018 / PubMed / Full text

TGFB1

  • Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease. / 11.2017 / PubMed / Full text

TGFBR1

  • Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text

TGFBR2

  • TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis. / 08.05.2019 / PubMed / Full text

TGM2

  • Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases. / 11.2018 / PubMed / Full text

THBS1

  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text

THBS4

  • Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment. / 18.06.2019 / PubMed / Full text

THEMIS

  • Lifetime benefits of early detection and treatment of diabetic kidney disease. / 2019 / PubMed / Full text

THRB

  • Age-associated increase of thyroid hormone receptor β gene promoter methylation coexists with decreased gene expression. / 11.2018 / PubMed / Full text

TIMP2

  • The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma. / 2019 / PubMed / Full text

TINF2

  • Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening. / 04.2018 / PubMed / Full text

TJP1

  • Morphological and immunohistochemical characteristics of the equine corneal epithelium. / 11.2019 / PubMed / Full text

TLR3

  • Repetitive TLR3 activation in the lung induces skeletal muscle adaptations and cachexia. / 06.2018 / PubMed / Full text

TLR5

  • Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition. / 08.2018 / PubMed / Full text

TLR6

  • Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection. / 05.2018 / PubMed / Full text

TLR8

  • TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy. / 08.01.2019 / PubMed / Full text

TMEM119

  • Dexamethasone Induces a Specific Form of Ramified Dysfunctional Microglia. / 02.2019 / PubMed / Full text

TNFSF15

  • Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens. / 11.2018 / PubMed / Full text

TNNI1

  • Regular aerobic exercise-ameliorated troponin I carbonylation to mitigate aged rat soleus muscle functional recession. / 05.2019 / PubMed / Full text

TNP1

  • Cytological and molecular aspects of the ageing sperm. / 01.02.2019 / PubMed / Full text

TNP2

  • Cytological and molecular aspects of the ageing sperm. / 01.02.2019 / PubMed / Full text

TNPO3

  • Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

TOMM20

  • Effect of aging on mitochondria and metabolism of bovine granulosa cells. / 13.09.2020 / PubMed / Full text

TOP1

  • UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis. / 12.06.2018 / PubMed / Full text

TOR2A

  • The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. / 05.06.2018 / PubMed / Full text

TP53INP1

  • TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signaling. / 02.01.2019 / PubMed / Full text

TP53RK

  • Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text

TP73

  • G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. / 15.11.2017 / PubMed / Full text

TPH1

  • [i]Lactobacillus plantarum[/i] DR7 improved brain health in aging rats via the serotonin, inflammatory and apoptosis pathways. / 02.12.2020 / PubMed / Full text

TPP1

  • FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping. / 03.11.2020 / PubMed / Full text

TPRKB

  • Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text

TPX2

  • Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells. / 2018 / PubMed / Full text

TRAF2

  • The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium. / 12.2019 / PubMed / Full text

TRAP1

  • Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion. / 2019 / PubMed / Full text

TRAV1-2

TRAV27

  • Perturbed CD8 T cell immunity across universal influenza epitopes in the elderly. / 02.2018 / PubMed / Full text

TRBV19

  • Perturbed CD8 T cell immunity across universal influenza epitopes in the elderly. / 02.2018 / PubMed / Full text

TRIB2

  • TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling. / 12.12.2018 / PubMed / Full text

TRIB3

  • Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. / 2018 / PubMed / Full text

TRIM21

  • TRIM21 overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma. / 2020 / PubMed / Full text

TRIM27

  • TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination. / 04.12.2020 / PubMed / Full text

TRIM28

  • Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau. / 04.06.2018 / PubMed / Full text

TRIP13

  • BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome. / 02.01.2020 / PubMed / Full text

TRPC1

  • Ca entry via TRPC1 is essential for cellular differentiation and modulates secretion via the SNARE complex. / 01.07.2019 / PubMed / Full text

TRPC7

  • Nociceptive transient receptor potential canonical 7 (TRPC7) mediates aging-associated tumorigenesis induced by ultraviolet B. / 01.2020 / PubMed / Full text

TRPM6

  • Role of kinase-coupled TRP channels in mineral homeostasis. / 04.2018 / PubMed / Full text

TRPS1

  • miRNA expression profiling uncovers a role of miR-302b-3p in regulating skin fibroblasts senescence. / 01.2020 / PubMed / Full text

TRPV5

  • Changes in expression of klotho affect physiological processes, diseases, and cancer. / 01.2018 / PubMed / Full text

TRPV6

  • Changes in expression of klotho affect physiological processes, diseases, and cancer. / 01.2018 / PubMed / Full text

TSG101

  • Exosomal Notch3 from high glucose-stimulated endothelial cells regulates vascular smooth muscle cells calcification/aging. / 01.09.2019 / PubMed / Full text

TSHB

  • Adipose TSHB in Humans and Serum TSH in Hypothyroid Rats Inform About Cellular Senescence. / 2018 / PubMed / Full text

TSHR

  • TSH-independent release of thyroid hormones through cold exposure in aging rats. / 27.10.2017 / PubMed / Full text

TSPYL5

  • Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics. / 03.2019 / PubMed / Full text

TTL

  • Longitudinal Associations of Body Mass Index, Waist Circumference, and Waist-to-Hip Ratio with Biomarkers of Oxidative Stress in Older Adults: Results of a Large Cohort Study. / 2020 / PubMed / Full text

TXN

  • Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice. / 15.11.2017 / PubMed / Full text

TXNDC5

  • Genetic associations with age of menopause in familial longevity. / 10.2019 / PubMed / Full text

TXNRD1

  • The genetic component of human longevity: New insights from the analysis of pathway-based SNP-SNP interactions. / 06.2018 / PubMed / Full text

TYK2

  • Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses. / 04.2018 / PubMed / Full text

TYROBP

U2AF1

  • Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomic analysis of mRNA splicing relevant proteins in aging HSPCs. / 05.03.2020 / PubMed / Full text

UACA

  • Knockdown of [i]UACA[/i] inhibitsproliferation and invasion and promotes senescence of hepatocellular carcinoma cells. / 2018 / PubMed / Full text

UBB

  • Different Expression Levels of Human Mutant Ubiquitin B (UBB ) Can Modify Chronological Lifespan or Stress Resistance of [i]Saccharomyces cerevisiae[/i]. / 2018 / PubMed / Full text

UBC

  • Selection of a Real-Time PCR Housekeeping Gene Panel in Human Endothelial Colony Forming Cells for Cellular Senescence Studies. / 2019 / PubMed / Full text

UBE2E3

  • Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence. / 07.2018 / PubMed / Full text

UBE3A

  • Delayed loss of UBE3A reduces the expression of Angelman syndrome-associated phenotypes. / 2019 / PubMed / Full text

UBE4B

  • CircRNAs in the tree shrew ([i]Tupaia belangeri[/i]) brain during postnatal development and aging. / 30.04.2018 / PubMed / Full text

UBTF

  • Age-associated dysregulation of protein metabolism in the mammalian oocyte. / 12.2017 / PubMed / Full text

UCHL1

  • Abolishing UCHL1's hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice. / 04.11.2020 / PubMed / Full text

UCHL3

  • UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis. / 12.06.2018 / PubMed / Full text

UCN

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

UCN3

  • Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise-induced threshold shift. / 08.2019 / PubMed / Full text

UCP3

  • Integrated study on comparative transcriptome and skeletal muscle function in aged rats. / 01.2018 / PubMed / Full text

UGT2B28

  • Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a UGT2B28 genomic variation. / 05.12.2019 / PubMed / Full text

UGT2B7

  • Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. / 05.2019 / PubMed / Full text

UHRF1

  • MLL3 promotes the senescence of esophageal squamous cell carcinoma. / 2019 / PubMed / Full text

ULK2

  • miR-26a suppresses autophagy in swine Sertoli cells by targeting ULK2. / 08.2018 / PubMed / Full text

UMOD

  • The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes. / 03.2019 / PubMed / Full text

UNG

  • UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans. / 01.05.2018 / PubMed / Full text

UPF1

  • Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity. / 21.08.2017 / PubMed / Full text

UQCRC2

  • Elucidation of the mechanism of changes in the antioxidant function with the aging in the liver of the senescence-accelerated mouse P10 (SAMP10). / 06.2018 / PubMed / Full text

USF1

  • The rs2516839 variation of USF1 gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+ study. / 01.2019 / PubMed / Full text

USF2

  • Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice. / 15.10.2018 / PubMed / Full text

USP14

  • Low expression of aging-related [[NRXN3]] is associated with Alzheimer disease: A systematic review and meta-analysis. / 07.2018 / PubMed / Full text

USP15

  • Deficiency of parkin and PINK1 impairs age-dependent mitophagy in [i]Drosophila[/i]. / 29.05.2018 / PubMed / Full text

USP28

  • Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program. / 01.10.2017 / PubMed / Full text

USP30

  • Deficiency of parkin and PINK1 impairs age-dependent mitophagy in [i]Drosophila[/i]. / 29.05.2018 / PubMed / Full text

USP7

  • Deubiquitinase USP7 regulates [i]Drosophila[/i] aging through ubiquitination and autophagy. / 20.11.2020 / PubMed / Full text

USP8

  • Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction. / 04.2019 / PubMed / Full text

VAMP2

  • Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission. / 01.08.2018 / PubMed / Full text

VAMP8

VASH1

  • Double-Face of Vasohibin-1 for the Maintenance of Vascular Homeostasis and Healthy Longevity. / 01.06.2018 / PubMed / Full text

VASP

  • Reversal of Aging-Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein-Protein Interfaces. / 18.07.2018 / PubMed / Full text

VCL

  • The effects of different preservation methods on ide (Leuciscus idus) sperm and the longevity of sperm movement. / 04.2018 / PubMed / Full text

VCP

  • The role of air pollution and lung function in cognitive impairment. / 02.2018 / PubMed / Full text

VEGFA

  • APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease. / 03.2020 / PubMed / Full text

VEGFC

  • Proteomic profiling of follicle fluids after superstimulation in one-month-old lambs. / 02.2018 / PubMed / Full text

VEGFD

  • Single-Arm Resistance Training Study to Determine the Relationship between Training Outcomes and Muscle Growth Factor mRNAs in Older Adults Consuming Numerous Medications and Supplements. / 2018 / PubMed / Full text

VGLL4

  • The lncRNA MEG3/miR-16-5p/VGLL4 regulatory axis is involved in etoposide-induced senescence of tumor cells. / 03.11.2020 / PubMed / Full text

VHLL

  • The Monetary Valuation of Lifetime Health Improvement and Life Expectancy Gains in Turkey. / 29.09.2017 / PubMed / Full text

VIPR2

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

VPREB3

  • Age-related but not longevity-related genes are found by weighted gene co-expression network analysis in the peripheral blood cells of humans. / 19.01.2019 / PubMed / Full text

VPS13C

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

VPS13D

  • SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. / 04.07.2019 / PubMed / Full text

VPS29

  • Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development. / 16.01.2019 / PubMed / Full text

VPS35

  • Combined Proteomic and Metabolomic Profiling of the [i]Arabidopsis thaliana vps29[/i] Mutant Reveals Pleiotropic Functions of the Retromer in Seed Development. / 16.01.2019 / PubMed / Full text

VSIG4

  • Immune checkpoint protein VSIG4 as a biomarker of aging in murine adipose tissue. / 10.2020 / PubMed / Full text

WAS

  • Psychological stress exposure to aged mice causes abnormal feeding patterns with changes in the bout number. / 09.11.2017 / PubMed / Full text

WASL

  • Loss of Wasl improves pancreatic cancer outcome. / 21.05.2020 / PubMed / Full text

WDR5

  • Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16 . / 11.2019 / PubMed / Full text

WDR73

  • Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature. / 11.04.2019 / PubMed / Full text

WFDC2

  • Differences in biomarkers and molecular pathways according to age for patients with HFrEF. / 01.10.2020 / PubMed / Full text

WFIKKN1

  • Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults. / 01.01.2019 / PubMed / Full text

WFIKKN2

  • Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography-Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults. / 01.01.2019 / PubMed / Full text

WLS

  • Evaluation of three statistical prediction models for forensic age prediction based on DNA methylation. / 05.2018 / PubMed / Full text

WNK1

  • Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2. / 10.2018 / PubMed / Full text

WNK4

  • Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2. / 10.2018 / PubMed / Full text

WNT10A

  • Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development. / 01.04.2020 / PubMed / Full text

WNT16

  • Inducible [i]Wnt16[/i] inactivation: WNT16 regulates cortical bone thickness in adult mice. / 05.2018 / PubMed / Full text

WNT3

  • Role of CD133 Molecule in Wnt Response and Renal Repair. / 03.2018 / PubMed / Full text

WNT5A

WNT7A

  • Exogenous Expression of WNT7A in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents. / 2020 / PubMed / Full text

WT1

  • Age and weight at first mating affects plasma leptin concentration but no effects on reproductive performance of gilts. / 09.2019 / PubMed / Full text

WWP1

  • The ubiquitin ligase WWP1 contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart. / 01.10.2020 / PubMed / Full text

XDH

  • Enhancing xanthine dehydrogenase activity is an effective way to delay leaf senescence and increase rice yield. / 11.03.2020 / PubMed / Full text

XG

  • The effect of administration media on palatability and ease of swallowing of multiparticulate formulations. / 15.11.2018 / PubMed / Full text

XPC

  • MicroRNA binding mediated Functional sequence variant in 3'-UTR of DNA repair Gene XPC in Age-related Cataract. / 12.10.2018 / PubMed / Full text

XPO1

  • Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan. / 15.05.2018 / PubMed / Full text

XRCC4

  • The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity. / 2018 / PubMed / Full text

YES1

  • Re-exploring the core genes and modules in the human frontal cortex during chronological aging: insights from network-based analysis of transcriptomic studies. / 20.10.2018 / PubMed / Full text

ZBTB16

  • miR-19b-3p induces cell proliferation and reduces heterochromatin-mediated senescence through PLZF in goat male germline stem cells. / 06.2018 / PubMed / Full text

ZFHX3

  • Shift work, DNA methylation and epigenetic age. / 01.10.2019 / PubMed / Full text

ZFPM2

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

ZNF207

  • Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. / 02.2018 / PubMed / Full text

ZNF396

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

ZNF467

  • Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology. / 15.11.2018 / PubMed / Full text

ZNF521

  • Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells. / 21.06.2019 / PubMed / Full text
Источник — https://transhumanist.ru/index.php?title=Aging_genes_1-2&oldid=2694