https://transhumanist.ru/index.php?action=history&feed=atom&title=ZNF804AZNF804A - История изменений2026-06-11T22:41:17ZИстория изменений этой страницы в викиMediaWiki 1.43.6https://transhumanist.ru/index.php?title=ZNF804A&diff=5618&oldid=prevOdysseusBot: Новая страница: «Zinc finger protein 804A [C2orf10] ==Publications== {{medline-entry |title=ZNF804A may be associated with executive control of attention. |pubmed-url=https:...»2021-05-12T13:52:25Z<p>Новая страница: «Zinc finger protein 804A [C2orf10] ==Publications== {{medline-entry |title=<a href="/ZNF804A" title="ZNF804A">ZNF804A</a> may be associated with executive control of attention. |pubmed-url=https:...»</p>
<p><b>Новая страница</b></p><div>Zinc finger protein 804A [C2orf10]<br />
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==Publications==<br />
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{{medline-entry<br />
|title=[[ZNF804A]] may be associated with executive control of attention.<br />
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/21040459<br />
|abstract=[[ZNF804A]], encoding the transcription factor zinc-finger protein 804A, is a genome-wide supported psychosis gene associated with schizophrenia and bipolar disorder. However, only little information is available on the role of [[ZNF804A]] regarding the cognitive phenotype of psychosis. In this study, we investigated the relationship between the single-nucleotide polymorphism rs1344706 (A/C, A = risk allele) in [[ZNF804A]] and attention in 200 healthy volunteers. We used the attention network test, which was designed to separate the three main components of attention (alerting, orienting and executive control). Results showed a significant association with the executive control network: the A/A genotype and the A-allele were associated with increased reaction time when conflicting information was present. In contrast, rs1344706 was not related to alerting and orienting. These results suggest that the genome-wide supported psychosis risk variant of [[ZNF804A]] is associated with altered executive control (larger conflict effect), which is a potential endophenotype of psychotic disorders.<br />
|mesh-terms=* Adult<br />
* Aging<br />
* Alleles<br />
* Attention<br />
* DNA<br />
* Data Interpretation, Statistical<br />
* Executive Function<br />
* Female<br />
* Genotype<br />
* Humans<br />
* Kruppel-Like Transcription Factors<br />
* Male<br />
* Nerve Net<br />
* Neuropsychological Tests<br />
* Orientation<br />
* Polymorphism, Genetic<br />
* Psychotic Disorders<br />
* Reaction Time<br />
* Regression Analysis<br />
* Reverse Transcriptase Polymerase Chain Reaction<br />
* Schizophrenia<br />
* Sex Characteristics<br />
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|full-text-url=https://sci-hub.do/10.1111/j.1601-183X.2010.00657.x<br />
}}</div>OdysseusBot