https://transhumanist.ru/index.php?action=history&feed=atom&title=TRA2BTRA2B - История изменений2026-06-24T01:55:26ZИстория изменений этой страницы в викиMediaWiki 1.43.6https://transhumanist.ru/index.php?title=TRA2B&diff=5210&oldid=prevOdysseusBot: Новая страница: «Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B) [SFRS10] ==...»2021-05-12T13:34:19Z<p>Новая страница: «Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B) [SFRS10] ==...»</p>
<p><b>Новая страница</b></p><div>Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B) [SFRS10]<br />
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==Publications==<br />
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{{medline-entry<br />
|title=Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.<br />
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/21102462<br />
|abstract=To identify loci for age at menarche, we performed a meta-analysis of 32 genome-wide association studies in 87,802 women of European descent, with replication in up to 14,731 women. In addition to the known loci at [[LIN28B]] (P = 5.4 × 10⁻⁶⁰) and 9q31.2 (P = 2.2 × 10⁻³³), we identified 30 new menarche loci (all P < 5 × 10⁻⁸) and found suggestive evidence for a further 10 loci (P < 1.9 × 10⁻⁶). The new loci included four previously associated with body mass index (in or near [[FTO]], [[SEC16B]], [[TRA2B]] and TMEM18), three in or near other genes implicated in energy homeostasis (BSX, [[CRTC1]] and MCHR2) and three in or near genes implicated in hormonal regulation (INHBA, [[PCSK2]] and RXRG). Ingenuity and gene-set enrichment pathway analyses identified coenzyme A and fatty acid biosynthesis as biological processes related to menarche timing.<br />
|mesh-terms=* Adolescent<br />
* Aging<br />
* Body Height<br />
* Body Size<br />
* Child<br />
* DNA Copy Number Variations<br />
* Female<br />
* Genetic Loci<br />
* Genetic Predisposition to Disease<br />
* Genome-Wide Association Study<br />
* Humans<br />
* Inheritance Patterns<br />
* Menarche<br />
* Obesity<br />
* Polymorphism, Single Nucleotide<br />
* Quantitative Trait Loci<br />
* Reproducibility of Results<br />
* Time Factors<br />
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|full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140055<br />
}}</div>OdysseusBot