https://transhumanist.ru/index.php?action=history&feed=atom&title=TECTATECTA - История изменений2026-11-08T23:43:00ZИстория изменений этой страницы в викиMediaWiki 1.43.6https://transhumanist.ru/index.php?title=TECTA&diff=5567&oldid=prevOdysseusBot: Новая страница: «Alpha-tectorin precursor ==Publications== {{medline-entry |title=Quantification of TECTA and DFNA5 expression in the developing mouse cochlea. |pubmed-url=h...»2021-05-12T13:50:05Z<p>Новая страница: «Alpha-tectorin precursor ==Publications== {{medline-entry |title=Quantification of <a href="/TECTA" title="TECTA">TECTA</a> and DFNA5 expression in the developing mouse cochlea. |pubmed-url=h...»</p>
<p><b>Новая страница</b></p><div>Alpha-tectorin precursor<br />
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==Publications==<br />
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{{medline-entry<br />
|title=Quantification of [[TECTA]] and DFNA5 expression in the developing mouse cochlea.<br />
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/11711860<br />
|abstract=[[TECTA]] and DFNA5 are the mouse orthologues of the human deafness-associated genes [[TECTA]] and DFNA5. To determine how expression of these genes is regulated during development, relative mRNA abundance was examined in mice by non-radioactive RT-PCR. [[TECTA]] mRNA was detected on embryonic day 15 (E15), increased to its highest level on postnatal day 3 (P3) and then dramatically decreased by P15. Low levels persisted (adulthood, P45 to 67) with mean mRNA abundance after P15 less than 25% of P3 levels. DFNA5 mRNA expression was constant throughout these time points. These results imply that [[TECTA]] is transcribed at a particularly high level during tectorial membrane morphogenesis. In contrast, DFNA5 is present in both the developing and mature cochlea.<br />
|mesh-terms=* Aging<br />
* Animals<br />
* Animals, Newborn<br />
* Carrier Proteins<br />
* Cochlea<br />
* Deafness<br />
* Extracellular Matrix Proteins<br />
* Female<br />
* Fetus<br />
* GPI-Linked Proteins<br />
* Gene Expression Regulation, Developmental<br />
* Glyceraldehyde-3-Phosphate Dehydrogenases<br />
* Membrane Glycoproteins<br />
* Mice<br />
* Mice, Inbred BALB C<br />
* RNA, Messenger<br />
* Receptors, Estrogen<br />
* Reverse Transcriptase Polymerase Chain Reaction<br />
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|full-text-url=https://sci-hub.do/10.1097/00001756-200110290-00016<br />
}}</div>OdysseusBot