https://transhumanist.ru/index.php?action=history&feed=atom&title=RGS5 2026-06-22T00:37:49Z История изменений этой страницы в вики MediaWiki 1.43.6 https://transhumanist.ru/index.php?title=RGS5&diff=5589&oldid=prev 2021-05-12T13:51:09Z

<p>Новая страница: «Regulator of G-protein signaling 5 (RGS5) ==Publications== {{medline-entry |title=Cardiac myocytes express mRNA for ten RGS proteins: changes in RGS mRNA expres...»</p> <p><b>Новая страница</b></p><div>Regulator of G-protein signaling 5 (RGS5)<br /> <br /> ==Publications==<br /> <br /> {{medline-entry<br /> |title=Cardiac myocytes express mRNA for ten RGS proteins: changes in RGS mRNA expression in ventricular myocytes and cultured atria.<br /> |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/9827562<br /> |abstract=Regulators of G-protein signalling (RGS) are recently identified proteins that shorten the lifetime of the activated G protein. We now show that rat cardiac myocytes express mRNA for at least 10 RGS. The mRNA for RGS-r is barely detectable in rat ventricles, but increases more than 20-fold during the 60- to 90-min process of isolating ventricular myocytes, and after 90 min of culture of atrial pieces in medium with Ca2 . Both in myocytes and in atria, the rise in RGS-r is transient. The mRNA for cardiac [[RGS5]], but not RGS-r, is developmentally regulated. These studies suggest that rapid regulation of RGS levels may be a new mechanism that governs how signals are transmitted across the cardiac cell membrane.<br /> |mesh-terms=* Aging<br /> * Animals<br /> * Animals, Newborn<br /> * Cell Membrane<br /> * Cells, Cultured<br /> * Eye Proteins<br /> * GTP-Binding Proteins<br /> * GTPase-Activating Proteins<br /> * Gene Expression Regulation<br /> * Heart<br /> * Heart Atria<br /> * Heart Ventricles<br /> * Kinetics<br /> * Myocardium<br /> * Organ Specificity<br /> * Protein Biosynthesis<br /> * Proteins<br /> * RGS Proteins<br /> * RNA, Messenger<br /> * Rats<br /> * Reverse Transcriptase Polymerase Chain Reaction<br /> * Signal Transduction<br /> * Transcription, Genetic<br /> <br /> |full-text-url=https://sci-hub.do/10.1016/s0014-5793(98)01319-2<br /> }}</div>

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