https://transhumanist.ru/index.php?action=history&feed=atom&title=MT4MT4 - История изменений2026-06-09T06:08:20ZИстория изменений этой страницы в викиMediaWiki 1.43.6https://transhumanist.ru/index.php?title=MT4&diff=5574&oldid=prevOdysseusBot: Новая страница: «Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV) ==Publications== {{medline-entry |title=Expression pattern of four membrane-type matrix metalloproteinases...»2021-05-12T13:50:23Z<p>Новая страница: «Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV) ==Publications== {{medline-entry |title=Expression pattern of four membrane-type matrix metalloproteinases...»</p>
<p><b>Новая страница</b></p><div>Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV)<br />
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==Publications==<br />
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{{medline-entry<br />
|title=Expression pattern of four membrane-type matrix metalloproteinases in the normal and diseased mouse mammary gland.<br />
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/15895410<br />
|abstract=Both mammary gland development and mammary carcinogenesis involve extensive remodeling of the mammary gland extracellular matrix. The expression of four membrane-type matrix metalloproteinases (MT-MMPs) with matrix remodeling potential in development and tumorigenesis was evaluated by in-situ hybridization on mouse mammary gland sections. MT1-MMP and [[MT3]]-MMP were found in the mammary stroma mainly around epithelial structures in both developing and mature mammary gland. In contrast, MT2-MMP was found exclusively in the mammary epithelium. Lactating gland expressed none of the examined MT-MMPs. Mammary gland tumors expressed MT1-MMP, MT2-MMP, and [[MT3]]-MMP while [[MT4]]-MMP was not expressed in any developmental or cancerous stage analyzed here. Our results suggest that MT1-MMP, MT2-MMP, and [[MT3]]-MMP may be involved in remodeling of both the normal and diseased mammary gland either directly or indirectly by activation of other MMPs.<br />
|mesh-terms=* Aging<br />
* Animals<br />
* Female<br />
* Gene Expression Profiling<br />
* Gene Expression Regulation, Enzymologic<br />
* Health<br />
* Lactation<br />
* Mammary Glands, Animal<br />
* Mammary Neoplasms, Animal<br />
* Matrix Metalloproteinase 14<br />
* Matrix Metalloproteinase 15<br />
* Matrix Metalloproteinase 16<br />
* Matrix Metalloproteinases, Membrane-Associated<br />
* Metalloendopeptidases<br />
* Mice<br />
* Pregnancy<br />
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|full-text-url=https://sci-hub.do/10.1002/jcp.20385<br />
}}</div>OdysseusBot