https://transhumanist.ru/index.php?action=history&feed=atom&title=MED28 2026-06-15T01:44:09Z История изменений этой страницы в вики MediaWiki 1.43.6 https://transhumanist.ru/index.php?title=MED28&diff=4706&oldid=prev 2021-04-29T19:30:48Z

<p>Новая страница: «Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal pro...»</p> <p><b>Новая страница</b></p><div>Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1) [EG1] [FKSG20]<br /> <br /> ==Publications==<br /> <br /> {{medline-entry<br /> |title=Redox regulation of the [[MED28]] and MED32 mediator subunits is important for development and senescence.<br /> |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26195288<br /> |abstract=Mediator is a conserved multi-protein complex that acts as a bridge between promoter-bound transcriptional regulators and RNA polymerase II. While redox signaling is important in adjusting plant metabolism and development, the involvement of Mediator in redox homeostasis and regulation only recently started to emerge. Our previous results show that the MED10a, [[MED28]], and MED32 Mediator subunits form various types of covalent oligomers linked by intermolecular disulfide bonds in vitro. To link that with biological significance we have characterized Arabidopsis med32 and med28 mutants and found that they are affected in root development and senescence, phenotypes possibly associated to redox changes. <br /> |mesh-terms=* Arabidopsis<br /> * Arabidopsis Proteins<br /> * Gene Expression Regulation, Plant<br /> * Hydrogen Peroxide<br /> * Mediator Complex<br /> * Mutation<br /> * Oxidation-Reduction<br /> * Plant Roots<br /> |keywords=* Mediator<br /> * Oligomerization<br /> * Redox<br /> * Root development<br /> * Senescence<br /> |full-text-url=https://sci-hub.do/10.1007/s00709-015-0853-y<br /> }}</div>

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