https://transhumanist.ru/index.php?action=history&feed=atom&title=GCG 2026-06-15T01:28:28Z История изменений этой страницы в вики MediaWiki 1.43.6 https://transhumanist.ru/index.php?title=GCG&diff=5078&oldid=prev 2021-05-12T13:28:15Z

<p>Новая страница: «Pro-glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXM) (OXY); Glucagon; Glucagon-like peptide 1 (GLP-1) (Incretin...»</p> <p><b>Новая страница</b></p><div>Pro-glucagon precursor [Contains: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXM) (OXY); Glucagon; Glucagon-like peptide 1 (GLP-1) (Incretin hormone); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)]<br /> <br /> ==Publications==<br /> <br /> {{medline-entry<br /> |title=Apolipoprotein E and longevity among Han Chinese population.<br /> |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/9792194<br /> |abstract=The apolipoprotein E gene ([[APOE]]), which locates on chromosome 19, has three common [[APOE]] alleles encoding [[APOE]]*2, [[APOE]]*3, [[APOE]]*4. It has been considered to be closely associated with human longevity among Western population. However, the allele frequency varies among racial and ethnic groups. We studied the relationship between [[APOE]] and longevity among 1562 Han Chinese (246 female and 1316 male) whose ages ranged from 20-108 years old in Shanghai metropolitan area and Lian Yungang, Jiangsu province. [[APOE]] was amplified by one-stage PCR using the forward primer: 5&#039;-GGC ACG GCT GTC CAA GGA GCT-3&#039; and reverse primer: 5&#039;-GAT GGC GCT GAG GCC [[GCG]] CT-3&#039;. The PCR product was digested directly with 5 U of CfoI and separated by a 20% polyacrylamide (acrylamide:bisacrylamide = 29:1) nondenaturing gel. The allele frequency of [[APOE]]*4 in thevery old age group (&gt; or = 85 years) was significantly different from that in the youth (20-39 years), middle (40-59 years) and old (60-84 years) age group (2.5% vs 8.4, 7.9 or 7.6%; P &lt; 0.05), respectively.<br /> |mesh-terms=* Adult<br /> * Age Distribution<br /> * Aged<br /> * Aged, 80 and over<br /> * Alleles<br /> * Apolipoproteins E<br /> * Asian Continental Ancestry Group<br /> * Female<br /> * Gene Frequency<br /> * Genotype<br /> * Humans<br /> * Longevity<br /> * Male<br /> * Middle Aged<br /> * Sex Distribution<br /> <br /> |full-text-url=https://sci-hub.do/10.1016/s0047-6374(98)00067-0<br /> }}</div>

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