https://transhumanist.ru/index.php?action=history&feed=atom&title=FMC1 2026-08-30T08:23:34Z История изменений этой страницы в вики MediaWiki 1.43.6 https://transhumanist.ru/index.php?title=FMC1&diff=5488&oldid=prev 2021-05-12T13:46:19Z

<p>Новая страница: «FMC1 homolog (ATP synthase assembly factor FMC1, mitochondrial) (Formation of mitochondrial complex V assembly factor 1 homolog) [C7orf55] [HSPC268] ==Publicatio...»</p> <p><b>Новая страница</b></p><div>FMC1 homolog (ATP synthase assembly factor FMC1, mitochondrial) (Formation of mitochondrial complex V assembly factor 1 homolog) [C7orf55] [HSPC268]<br /> <br /> ==Publications==<br /> <br /> {{medline-entry<br /> |title=Monoclonal antibody-defined B cell subsets in aging humans and Down&#039;s syndrome.<br /> |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/6240431<br /> |abstract=Peripheral blood from aging and young humans and patients with Down&#039;s syndrome, and from age- and sex-matched controls, was studied for the proportions of surface immunoglobulin (SIg ) bearing and monoclonal antibodies [[FMC1]], and FMC7 defined B lymphocytes and B lymphocyte subsets using fluorescent-activated cell sorter. In aging humans, the proportion of SIg and [[FMC1]] (that detect all B lymphocytes) were comparable to simultaneously studied healthy young controls. However, FMC7 (that detects a subset of B cells) B cells were significantly (p less than 0.05) increased when compared to young subjects. In aging subjects, the proportions of FMC7 B cells were comparable to their [[FMC1]] B cells, whereas in young subjects FMC7 B cells were a subset of [[FMC1]] B cells. In Down&#039;s syndrome, a phenomenon similar to aging humans was observed, that is the proportions of FMC7 were increased when compared to age- and sex-matched controls and were comparable to their own [[FMC1]] B cells. This study demonstrates the abnormality of B lymphocytes in human aging and Down&#039;s syndrome. The significance of these findings is discussed.<br /> |mesh-terms=* Adult<br /> * Aged<br /> * Aging<br /> * Antibodies, Monoclonal<br /> * B-Lymphocytes<br /> * Child<br /> * Child, Preschool<br /> * Down Syndrome<br /> * Female<br /> * Humans<br /> * Male<br /> * Receptors, Antigen, B-Cell<br /> * Reference Values<br /> <br /> |full-text-url=https://sci-hub.do/10.1159/000212661<br /> }}</div>

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