https://transhumanist.ru/index.php?action=history&feed=atom&title=FGL2 2026-04-08T08:35:50Z История изменений этой страницы в вики MediaWiki 1.43.6 https://transhumanist.ru/index.php?title=FGL2&diff=6561&oldid=prev 2021-05-12T15:37:14Z

<p>Новая страница: «Fibroleukin precursor (Fibrinogen-like protein 2) (pT49) ==Publications== {{medline-entry |title=Developmental expression of B cell molecules in equine lymphoid...»</p> <p><b>Новая страница</b></p><div>Fibroleukin precursor (Fibrinogen-like protein 2) (pT49)<br /> <br /> ==Publications==<br /> <br /> {{medline-entry<br /> |title=Developmental expression of B cell molecules in equine lymphoid tissues.<br /> |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28063478<br /> |abstract=Identification and classification of B cell subpopulations has been shown to be challenging and inconsistent among different species. Our study tested aspects of ontogeny, phenotype, tissue distribution, and function of equine [[CD5]] B cells, which represented a greater proportion of B cells early in development and in the peritoneal cavity. [[CD5]] and [[CD5]] B cells differentially expressed B cell markers (CD2, CD21, IgM) measured using flow cytometry, but similar mRNA expression of signature genes (DGKA, [[FGL2]], [[PAX5]], [[IGHM]], IL10) measured using quantitative RT-PCR. Sequencing lambda light chain segments revealed that [[CD5]] B cells generated diverse immunoglobulin repertoires, and more frequently bound to fluorescence-labeled phosphorylcholine. This study shows developmental characteristics and tissue distribution of a newly described subpopulation of B cells in the horse.<br /> |mesh-terms=* Aging<br /> * Animals<br /> * B-Lymphocyte Subsets<br /> * B-Lymphocytes<br /> * CD5 Antigens<br /> * Flow Cytometry<br /> * Horses<br /> * Immunoglobulin Light Chains<br /> * Immunophenotyping<br /> * Lymphoid Tissue<br /> * Phosphorylcholine<br /> |keywords=* B cell<br /> * CD5<br /> * Development<br /> * Equine<br /> * Immunoglobulin repertoire<br /> |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267323<br /> }}</div>

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