https://transhumanist.ru/index.php?action=history&feed=atom&title=DEGS1 2026-10-13T01:05:31Z История изменений этой страницы в вики MediaWiki 1.43.6 https://transhumanist.ru/index.php?title=DEGS1&diff=6364&oldid=prev 2021-05-12T15:26:44Z

<p>Новая страница: «Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Cell migration-inducing gene 15 protein) (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-...»</p> <p><b>Новая страница</b></p><div>Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Cell migration-inducing gene 15 protein) (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-1) (Membrane lipid desaturase) [DES1] [MLD] [MIG15]<br /> <br /> ==Publications==<br /> <br /> {{medline-entry<br /> |title=[Frailty: Prevalence in the Resident Population of Germany 70 - 79 Years of Age - a Population-Based Approach].<br /> |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/29156480<br /> |abstract=In all countries life expectancy is rising, and many older persons spend a longer period in good health. Nevertheless, frailty is present in older people and can be considered as a risk factor for limitations. The &quot;German Health Interview and Examination Survey for Adults&quot; ([[DEGS1]]) 2008 - 2011 comprised interviews, examinations and tests. Data on 1110 community-dwelling people aged 70 to 79 years participating in [[DEGS1]] with full records on frailty were analysed. Physical frailty was defined as exhaustion (SF-36 item), low grip strength, slowness (Timed Up-and-Go test &gt; 15 seconds or unable to perform) and low physical activity (no sports or exertion). In men 36,6% (CI 32,2 - 41,2) were classified as pre-frail, 2,5% (CI 1,4 - 4,4) as frail; in women 41,8% (CI 37,3 - 46,5) were classified as pre-frail, and 2,9% (CI 1,9 - 4,5) as frail. Frail persons significantly show more polypharmacy, recurrent falls, receive more frequently nursing care financial benefits, are officially recognized disabled and have poor social support. This population-based information may help to identify frail people with high risk of adverse health outcomes. Prediction models in operative anaesthesiology for specific health care settings should be developed.<br /> |mesh-terms=* Aged<br /> * Female<br /> * Frail Elderly<br /> * Frailty<br /> * Geriatrics<br /> * Germany<br /> * Humans<br /> * Male<br /> * Prevalence<br /> <br /> |full-text-url=https://sci-hub.do/10.1055/s-0043-105841<br /> }}<br /> {{medline-entry<br /> |title=Physical exercise and cognitive function across the life span: Results of a nationwide population-based study.<br /> |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/28919495<br /> |abstract=To examine cross-sectional and longitudinal associations between physical exercise and cognitive function across different age groups in a nationwide population-based sample of adults aged 18-79 years in Germany. Cross-sectional/prospective. Cognitive function was assessed in the mental health module of the German Health Interview and Examination Survey for Adults ([[DEGS1]]-MH, 2009-2012, n=3535), using a comprehensive neuropsychological test battery. Cognitive domain scores for executive function and memory were derived from confirmatory factor analysis. Regular physical exercise in the last three months was assessed by self-report and defined as no exercise, &lt;2 and ≥2h (hours) of exercise per week. A subgroup of [[DEGS1]]-MH participants who previously participated in the German National Health Interview and Examination Survey 1998 (GNHIES98, 1997-1999, n=1624) enabled longitudinal analyses with a mean follow-up of 12.4 years. Compared to no exercise, more weekly physical exercise was associated with better executive function in cross-sectional (&lt;2h: β=0.12; ≥2h: β=0.17; all p&lt;0.001) and longitudinal analyses (&lt;2h: β=0.14, p&lt;0.001; ≥2h: β=0.15, p=0.001) using linear regression models adjusted for age, sex, education, smoking, alcohol consumption, fruit and vegetable consumption and obesity. Slightly weaker associations were found for memory in cross-sectional (&lt;2h: β=0.08, p=0.009; ≥2h: β=0.08, p=0.026) and longitudinal analysis (&lt;2h: β=0.09, p=0.036; ≥2h: β=0.08, p=0.114). There was no evidence of interaction between physical exercise and age. Higher levels of physical exercise were associated with better executive function and memory in cross-sectional and longitudinal analyses with no evidence for differential effects by age.<br /> |mesh-terms=* Adolescent<br /> * Adult<br /> * Age Factors<br /> * Aged<br /> * Cognition<br /> * Cognitive Aging<br /> * Cross-Sectional Studies<br /> * Executive Function<br /> * Exercise<br /> * Female<br /> * Humans<br /> * Linear Models<br /> * Longevity<br /> * Longitudinal Studies<br /> * Male<br /> * Memory<br /> * Middle Aged<br /> * Neuropsychological Tests<br /> * Population Surveillance<br /> * Prospective Studies<br /> * Self Report<br /> * Young Adult<br /> |keywords=* Executive function<br /> * Health examination survey<br /> * Longitudinal studies<br /> * Memory<br /> * Neuropsychological assessment<br /> * Risk factors<br /> |full-text-url=https://sci-hub.do/10.1016/j.jsams.2017.08.022<br /> }}</div>

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