https://transhumanist.ru/index.php?action=history&feed=atom&title=DEFB1DEFB1 - История изменений2026-04-12T14:23:44ZИстория изменений этой страницы в викиMediaWiki 1.43.6https://transhumanist.ru/index.php?title=DEFB1&diff=6363&oldid=prevOdysseusBot: Новая страница: «Beta-defensin 1 precursor (BD-1) (hBD-1) (Defensin, beta 1) [BD1] [HBD1] ==Publications== {{medline-entry |title=Association of Polymorphisms in Innate Immunity...»2021-05-12T15:26:40Z<p>Новая страница: «Beta-defensin 1 precursor (BD-1) (hBD-1) (Defensin, beta 1) [BD1] [HBD1] ==Publications== {{medline-entry |title=Association of Polymorphisms in Innate Immunity...»</p>
<p><b>Новая страница</b></p><div>Beta-defensin 1 precursor (BD-1) (hBD-1) (Defensin, beta 1) [BD1] [HBD1]<br />
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==Publications==<br />
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{{medline-entry<br />
|title=Association of Polymorphisms in Innate Immunity Genes [[TLR9]] and [[DEFB1]] with Human Longevity.<br />
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/26028230<br />
|abstract=The distribution of polymorphic variants of innate immunity genes [[TLR9]] ( 2848G>A) and [[DEFB1]](-20G>A; -44C>G; -52G>A) was evaluated in long-living individuals. No significant differences were found in the distribution of genotypes and alleles of the [[TLR9]] gene. The following features were revealed: increase in the frequency of AA and GG genotypes and decrease in the frequency of the AG genotype of the [[DEFB1]](-20G>A) gene; increase in the frequency of the CC genotype and C allele and decrease in the frequency of CG and GG genotypes and G allele of the [[DEFB1]](44C>G) gene; and increase in the frequency of AA and AG genotypes and A allele and decrease in the frequency of the GG genotypes and G allele of the [[DEFB1]](-52G>A) gene. Genotypes and alleles of the [[DEFB1]] gene found in long-living individuals can be considered as the factors that increase the probability of longevity and favorable course of age-related diseases. <br />
|mesh-terms=* Adult<br />
* Aged, 80 and over<br />
* Aging<br />
* Alleles<br />
* DNA<br />
* Gene Frequency<br />
* Humans<br />
* Immunity, Innate<br />
* Longevity<br />
* Middle Aged<br />
* Polymorphism, Single Nucleotide<br />
* Signal Transduction<br />
* Toll-Like Receptor 9<br />
* Young Adult<br />
* beta-Defensins<br />
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|full-text-url=https://sci-hub.do/10.1007/s10517-015-2894-9<br />
}}</div>OdysseusBot