https://transhumanist.ru/index.php?action=history&feed=atom&title=CYP2W1 2026-06-10T09:19:12Z История изменений этой страницы в вики MediaWiki 1.43.6 https://transhumanist.ru/index.php?title=CYP2W1&diff=5510&oldid=prev 2021-05-12T13:47:31Z

<p>Новая страница: «Cytochrome P450 2W1 precursor (EC 1.14.14.-) (CYPIIW1) ==Publications== {{medline-entry |title=Expression patterns of mouse and human CYP orthologs (families 1-...»</p> <p><b>Новая страница</b></p><div>Cytochrome P450 2W1 precursor (EC 1.14.14.-) (CYPIIW1)<br /> <br /> ==Publications==<br /> <br /> {{medline-entry<br /> |title=Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.<br /> |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/15752708<br /> |abstract=The present study compared the relative expression pattern of 10 orthologous CYP forms from families 1-4 in cDNA panels of human and mouse fetal and adult tissues. Except for [[CYP1A2]], all of these CYPs exhibited specific patterns of expression during mouse ontogeny, suggesting possible involvement in development. Cyp1a1 and Cyp2r1 were the only two of the orthologs to be expressed only in the E7 mouse; Cyp2s1 was expressed in all stages, including E7, while Cyp2e1 appeared only at E17. Highest expression of the individual CYPs in the different late term human fetal tissues was: thymus, [[CYP1B1]] and [[CYP2U1]]; liver, CYP2E1; brain, [[CYP2R1]], [[CYP1A1]] and CYP4X1; and lung, [[CYP4B1]] and [[CYP2W1]]. In general, the level of individual human CYP transcripts was lower in the fetal than the corresponding adult tissues. The pattern of expression in adult mouse and human tissues was fairly similar for [[CYP1A1]], [[CYP1A2]], [[CYP1B1]], [[CYP2S1]], and [[CYP2U1]] orthologs.<br /> |mesh-terms=* Adult<br /> * Aging<br /> * Animals<br /> * Base Sequence<br /> * Cytochrome P-450 Enzyme System<br /> * DNA, Complementary<br /> * Embryo, Mammalian<br /> * Gene Expression Profiling<br /> * Gene Expression Regulation, Developmental<br /> * Humans<br /> * Mice<br /> * Organ Specificity<br /> <br /> |full-text-url=https://sci-hub.do/10.1016/j.abb.2005.02.001<br /> }}</div>

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