https://transhumanist.ru/index.php?action=history&feed=atom&title=CYP21A2 2026-10-23T15:07:03Z История изменений этой страницы в вики MediaWiki 1.43.6 https://transhumanist.ru/index.php?title=CYP21A2&diff=5507&oldid=prev 2021-05-12T13:47:08Z

<p>Новая страница: «Steroid 21-hydroxylase (EC 1.14.14.16) (21-OHase) (Cytochrome P-450c21) (Cytochrome P450 21) (Cytochrome P450 XXI) (Cytochrome P450-C21) (Cytochrome P450-C21B) [C...»</p> <p><b>Новая страница</b></p><div>Steroid 21-hydroxylase (EC 1.14.14.16) (21-OHase) (Cytochrome P-450c21) (Cytochrome P450 21) (Cytochrome P450 XXI) (Cytochrome P450-C21) (Cytochrome P450-C21B) [CYP21] [CYP21B]<br /> <br /> ==Publications==<br /> <br /> {{medline-entry<br /> |title=Transient hyper-17-OHPnemia unrelated to cross-reactions with residual fetal adrenal cortex products.<br /> |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/14988602<br /> |abstract=To clarify the pathogenesis of transient hyper-17alpha-hydroxyprogesteronemia, we initiated a laboratory investigation in a pre-term infant with persistently high serum 17alpha-hydroxyprogesterone (17-OHP) until 2 months of age. Serum 17-OHP level was measured by high-performance liquid chromatography and radioimmunoassay, and gene analysis of [[CYP21A2]] (21-hydroxylase) was performed. Serum 17-OHP level on the 29th day of life was 25.4 ng/ml, and the urinary steroid profile showed low pregnanetriolone. Gene analysis of 21-hydroxylase disclosed no mutation, and 17-OHP normalized by 3 months of age without specific treatment. Transient elevations in 17-OHP, which do not appear related to cross-reactions with products of a residual fetal adrenal cortex, may occur in the first few months of life.<br /> |mesh-terms=* 17-alpha-Hydroxyprogesterone<br /> * Adrenal Cortex<br /> * Adrenocorticotropic Hormone<br /> * Aging<br /> * Chromatography, High Pressure Liquid<br /> * Cross Reactions<br /> * Fetus<br /> * Humans<br /> * Infant, Newborn<br /> * Male<br /> * Polymerase Chain Reaction<br /> * Pregnanetriol<br /> * Radioimmunoassay<br /> * Steroid 21-Hydroxylase<br /> * Time Factors<br /> <br /> |full-text-url=https://sci-hub.do/10.1159/000076961<br /> }}</div>

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