https://transhumanist.ru/index.php?action=history&feed=atom&title=CRK 2026-08-17T18:11:19Z История изменений этой страницы в вики MediaWiki 1.43.6 https://transhumanist.ru/index.php?title=CRK&diff=6265&oldid=prev 2021-05-12T15:20:12Z

<p>Новая страница: «Adapter molecule crk (Proto-oncogene c-Crk) (p38) ==Publications== {{medline-entry |title=Crack-cocaine dependence and aging: effects on working memory. |pubmed...»</p> <p><b>Новая страница</b></p><div>Adapter molecule crk (Proto-oncogene c-Crk) (p38)<br /> <br /> ==Publications==<br /> <br /> {{medline-entry<br /> |title=Crack-cocaine dependence and aging: effects on working memory.<br /> |pubmed-url=https://pubmed.ncbi.nlm.nih.gov/27111700<br /> |abstract=To compare the working memory (WM) performance of young adult crack-cocaine dependent users, healthy older adults, and a control group of healthy young adults. A total of 77 female participants took part in this study: 26 young adult crack-cocaine dependent users ([[CRK]]), 19 healthy older adults (HO), and 32 healthy younger adults (HC). All participants completed the N-back verbal task. A multivariate analysis of covariance was performed. The model included education, income, and medication use as covariates. A group effect (F6,140 = 7.192, p &lt; 0.001) was found. Post-hoc analyses showed that the performance of the [[CRK]] and HO groups was reduced compared to the HC group in two N-back conditions. No differences between the HO and [[CRK]] groups on WM performance were found. [[CRK]] participants perform similar to HO participants on a WM task, despite the well-known effects of age on WM and the young age of [[CRK]]. These data point to a possible parallel between cognitive declines associated with crack use and developmental aging.<br /> |mesh-terms=* Adolescent<br /> * Adult<br /> * Aged<br /> * Aging<br /> * Case-Control Studies<br /> * Cocaine-Related Disorders<br /> * Crack Cocaine<br /> * Female<br /> * Humans<br /> * Memory, Short-Term<br /> * Neuropsychological Tests<br /> * Young Adult<br /> <br /> |full-text-url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115470<br /> }}</div>

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