https://transhumanist.ru/index.php?action=history&feed=atom&title=CRISP2CRISP2 - История изменений2026-09-29T00:10:01ZИстория изменений этой страницы в викиMediaWiki 1.43.6https://transhumanist.ru/index.php?title=CRISP2&diff=5389&oldid=prevOdysseusBot: Новая страница: «Cysteine-rich secretory protein 2 precursor (CRISP-2) (Cancer/testis antigen 36) (CT36) (Testis-specific protein TPX-1) [GAPDL5] [TPX1] ==Publications== {{medli...»2021-05-12T13:41:52Z<p>Новая страница: «Cysteine-rich secretory protein 2 precursor (CRISP-2) (Cancer/testis antigen 36) (CT36) (Testis-specific protein TPX-1) [GAPDL5] [TPX1] ==Publications== {{medli...»</p>
<p><b>Новая страница</b></p><div>Cysteine-rich secretory protein 2 precursor (CRISP-2) (Cancer/testis antigen 36) (CT36) (Testis-specific protein TPX-1) [GAPDL5] [TPX1]<br />
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==Publications==<br />
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{{medline-entry<br />
|title=Novel development-related alternative splices in human testis identified by cDNA microarrays.<br />
|pubmed-url=https://pubmed.ncbi.nlm.nih.gov/15713825<br />
|abstract=Alternative splicing of premessenger RNA is an important regulatory mechanism that increases the diversity of proteins transcribed from a single gene. This is particularly important in the testis because germ cell expansion and differentiation require many cellular changes and regulatory steps. To investigate novel development-related alternative splicings in the human testis, complementary DNA microarray studies were conducted with the use of probes from human fetal testes, adult testes, and human spermatozoa. Of a total of 386 Unigene clusters found to be related to the development of the testis, 67 clusters showed a total of 74 novel alternative spliceoforms. Developmental stage-dependent expression was also performed for a novel Unigene, NYD-SP20 (Hs.351068), which had 4 possible novel spliceoforms and another Unigene, [[CRISP2]] (cysteine-rich secretory protein 2, Hs.2042), which had 3 possible novel spliceoforms. These results indicate that alternative splicing plays an important role in the complicated processes of testis development and spermatogenesis.<br />
|mesh-terms=* Adult<br />
* Aged<br />
* Aging<br />
* Alternative Splicing<br />
* Base Sequence<br />
* DNA Primers<br />
* DNA, Complementary<br />
* Gene Expression Regulation, Developmental<br />
* Humans<br />
* Male<br />
* Oligonucleotide Array Sequence Analysis<br />
* Proteins<br />
* RNA, Messenger<br />
* Spermatozoa<br />
* Testis<br />
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|full-text-url=https://sci-hub.do/10.1002/j.1939-4640.2005.tb01085.x<br />
}}</div>OdysseusBot